Guide to the Human Genome
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Name: NOD2 Sequence: fasta or formatted (1040aa) NCBI GI: 11545912
Description:

nucleotide-binding oligomerization domain containing 2

Referenced in:

BCL2 Pathways, Caspases, and Programmed Cell Death
Pyrin and Associated Functions

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             9.5         99           3
 C cysteine            3.4         35           2
 D aspartate           4.1         43           2
 E glutamate           6.4         67           3
 F phenylalanine       4.2         44           2
 G glycine             6.9         72           2
 H histidine           3.6         37           2
 I isoleucine          2.5         26           1
 K lysine              3.6         37           2
 L leucine            16.9        176           3
 M methionine          1.5         16           1
 N asparagine          3.1         32           2
 P proline             4.3         45           2
 Q glutamine           5.3         55           2
 R arginine            5.8         60           2
 S serine              6.5         68           2
 T threonine           4.0         42           3
 V valine              5.1         53           2
 W tryptophan          1.7         18           1
 Y tyrosine            1.4         15           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   nucleotide-binding oligomerization domain containing... 
NOD1                  0.204   nucleotide-binding oligomerization domain containing ...
NLRC3                 0.090   NOD3 protein 
NLRP12                0.063   NLR family, pyrin domain containing 12 isoform 2 [Ho...
NLRP3                 0.058   NLR family, pyrin domain containing 3 isoform d [Ho...
NLRP3                 0.055   NLR family, pyrin domain containing 3 isoform a [Ho...
NLRP3                 0.055   NLR family, pyrin domain containing 3 isoform a [Hom...
NLRP3                 0.055   NLR family, pyrin domain containing 3 isoform c [Ho...
NLRP3                 0.055   NLR family, pyrin domain containing 3 isoform b [Hom...
NLRC5                 0.055   nucleotide-binding oligomerization domains 27 [Homo...
NLRP14                0.050   NLR family, pyrin domain containing 14 
CIITA                 0.048   class II transactivator 
NLRP1                 0.046   NLR family, pyrin domain containing 1 isoform 2 [Homo...
NLRP1                 0.046   NLR family, pyrin domain containing 1 isoform 4 [Hom...
NLRP1                 0.046   NLR family, pyrin domain containing 1 isoform 5 [Hom...
NLRP1                 0.046   NLR family, pyrin domain containing 1 isoform 3 [Hom...
NLRP1                 0.046   NLR family, pyrin domain containing 1 isoform 1 [Hom...
NLRP7                 0.044   NACHT, leucine rich repeat and PYD containing 7 isof...
NLRP4                 0.043   NLR family, pyrin domain containing 4 
NLRP13                0.041   NACHT, leucine rich repeat and PYD containing 13 [H...
NLRP6                 0.040   NLR family, pyrin domain containing 6 
NLRP9                 0.038   NLR family, pyrin domain containing 9 
NLRP10                0.038   NLR family, pyrin domain containing 10 
NLRP2                 0.036   NLR family, pyrin domain containing 2 
NLRP7                 0.033   NACHT, leucine rich repeat and PYD containing 7 iso...
NLRP7                 0.033   NACHT, leucine rich repeat and PYD containing 7 isof...
NLRP5                 0.032   NACHT, LRR and PYD containing protein 5 
NLRX1                 0.028   NLR family member X1 isoform 1 
NLRX1                 0.028   NLR family member X1 isoform 2 
RNH1                  0.027   ribonuclease/angiogenin inhibitor 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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