Guide to the Human Genome
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Name: CARD8 Sequence: fasta or formatted (431aa) NCBI GI: 7662404
Description:

caspase recruitment domain family, member 8

Referenced in:

BCL2 Pathways, Caspases, and Programmed Cell Death

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.6         24           2
 C cysteine            0.7          3           1
 D aspartate           5.1         22           2
 E glutamate           8.8         38           2
 F phenylalanine       4.9         21           1
 G glycine             5.6         24           2
 H histidine           3.5         15           2
 I isoleucine          4.4         19           1
 K lysine              4.6         20           2
 L leucine            11.6         50           2
 M methionine          2.1          9           2
 N asparagine          3.5         15           1
 P proline             5.6         24           3
 Q glutamine           4.6         20           2
 R arginine            4.2         18           1
 S serine              8.4         36           2
 T threonine           3.9         17           1
 V valine              7.9         34           1
 W tryptophan          1.6          7           1
 Y tyrosine            3.5         15           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   caspase recruitment domain family, member 8 
NLRP1                 0.329   NLR family, pyrin domain containing 1 isoform 3 [Hom...
NLRP1                 0.329   NLR family, pyrin domain containing 1 isoform 1 [Hom...
NLRP1                 0.291   NLR family, pyrin domain containing 1 isoform 5 [Hom...
NLRP1                 0.264   NLR family, pyrin domain containing 1 isoform 2 [Homo...
NLRP1                 0.264   NLR family, pyrin domain containing 1 isoform 4 [Hom...
NLRC4                 0.021   caspase recruitment domain protein 12 
CASP1                 0.019   caspase 1 isoform alpha precursor 
CASP1                 0.019   caspase 1 isoform beta precursor 
CARD16                0.019   caspase-1 dominant-negative inhibitor pseudo-ICE iso...
CARD16                0.019   caspase-1 dominant-negative inhibitor pseudo-ICE iso...
PYCARD                0.019   PYD and CARD domain containing isoform a 
CARD17                0.017   caspase recruitment domain family, member 17 
PYCARD                0.017   PYD and CARD domain containing isoform b 
CEP250                0.012   centrosomal protein 2 
CARD6                 0.009   caspase recruitment domain family, member 6 
CARD18                0.009   ICEBERG caspase-1 inhibitor 
KIF4A                 0.009   kinesin family member 4 
CASP2                 0.009   caspase 2 isoform 1 preproprotein 
BIRC3                 0.008   baculoviral IAP repeat-containing protein 3 
BIRC3                 0.008   baculoviral IAP repeat-containing protein 3 
FKBP15                0.008   FK506 binding protein 15, 133kDa 
CASP2                 0.007   caspase 2 isoform 3 
AFF1                  0.006   myeloid/lymphoid or mixed-lineage leukemia trithorax ...
RPGRIP1L              0.006   RPGRIP1-like isoform b 
RPGRIP1L              0.006   RPGRIP1-like isoform a 
FAM21A                0.006   hypothetical protein LOC387680 
FAM21C                0.006   hypothetical protein LOC253725 
GOLGA3                0.006   Golgi autoantigen, golgin subfamily a, 3 
FAM21B                0.006   hypothetical protein LOC55747 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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