Guide to the Human Genome
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Name: CASP1 Sequence: fasta or formatted (404aa) NCBI GI: 15431328
Description:

caspase 1 isoform alpha precursor

Referenced in:

BCL2 Pathways, Caspases, and Programmed Cell Death
Pyrin and Associated Functions

Other entries for this name:
alt prot [311aa] caspase 1 isoform gamma precursor
alt prot [263aa] caspase 1 isoform delta
alt prot [88aa] caspase 1 isoform epsilon
alt prot [383aa] caspase 1 isoform beta precursor
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.9         24           1
 C cysteine            3.0         12           1
 D aspartate           5.9         24           2
 E glutamate           7.7         31           2
 F phenylalanine       4.2         17           1
 G glycine             5.9         24           1
 H histidine           2.0          8           1
 I isoleucine          6.7         27           3
 K lysine              6.7         27           2
 L leucine             7.9         32           2
 M methionine          3.7         15           1
 N asparagine          4.0         16           1
 P proline             4.5         18           1
 Q glutamine           4.2         17           1
 R arginine            5.0         20           2
 S serine              8.2         33           2
 T threonine           6.4         26           2
 V valine              5.7         23           2
 W tryptophan          0.7          3           1
 Y tyrosine            1.7          7           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   caspase 1 isoform alpha precursor 
CASP1                 0.930   caspase 1 isoform beta precursor 
CASP1                 0.725   caspase 1 isoform gamma precursor 
CASP1                 0.572   caspase 1 isoform delta 
CASP4                 0.426   caspase 4 isoform alpha precursor 
CASP4                 0.395   caspase 4 isoform gamma precursor 
CASP5                 0.393   caspase 5 isoform b precursor 
CASP5                 0.390   caspase 5 isoform f precursor 
CASP5                 0.390   caspase 5 isoform a precursor 
CASP5                 0.378   caspase 5 isoform c 
CASP5                 0.299   caspase 5 isoform d 
CARD16                0.242   caspase-1 dominant-negative inhibitor pseudo-ICE iso...
CARD16                0.191   caspase-1 dominant-negative inhibitor pseudo-ICE iso...
CARD17                0.183   caspase recruitment domain family, member 17 
CASP1                 0.161   caspase 1 isoform epsilon 
CASP2                 0.108   caspase 2 isoform 1 preproprotein 
CARD18                0.091   ICEBERG caspase-1 inhibitor 
CASP9                 0.081   caspase 9 isoform alpha preproprotein 
CASP3                 0.070   caspase 3 preproprotein 
CASP3                 0.070   caspase 3 preproprotein 
CASP14                0.070   caspase 14 precursor 
CASP10                0.066   caspase 10 isoform d preproprotein 
CASP10                0.066   caspase 10 isoform b preproprotein 
CASP10                0.065   caspase 10 isoform a preproprotein 
CASP7                 0.056   caspase 7 isoform delta 
CASP7                 0.056   caspase 7 isoform alpha 
CASP7                 0.056   caspase 7 isoform alpha precursor 
CASP8                 0.051   caspase 8 isoform G precursor 
CASP8                 0.051   caspase 8 isoform B precursor 
CASP8                 0.051   caspase 8 isoform C precursor 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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