Guide to the Human Genome
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Search of human proteins with 10938016

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|10938016 claudin 11 [Homo sapiens]
         (207 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|10938016 claudin 11 [Homo sapiens]                                 427   e-120
gi|10863887 claudin 1 [Homo sapiens]                                  110   6e-25
gi|183979973 claudin 19 isoform a [Homo sapiens]                      105   4e-23
gi|183979975 claudin 19 isoform b [Homo sapiens]                      105   4e-23
gi|153792186 claudin 7 [Homo sapiens]                                 103   1e-22
gi|50345279 claudin 18 isoform 2 [Homo sapiens]                        95   4e-20
gi|7705961 claudin 18 isoform 1 [Homo sapiens]                         95   4e-20
gi|5921465 claudin 10 isoform b [Homo sapiens]                         94   1e-19
gi|195947374 claudin 5 [Homo sapiens]                                  94   1e-19
gi|195947372 claudin 5 [Homo sapiens]                                  94   1e-19
gi|7656981 claudin 15 [Homo sapiens]                                   90   1e-18
gi|11141861 claudin 9 [Homo sapiens]                                   90   2e-18
gi|33598916 claudin 10 isoform a [Homo sapiens]                        88   4e-18
gi|4502875 claudin 3 [Homo sapiens]                                    86   2e-17
gi|225703142 claudin 14 [Homo sapiens]                                 84   1e-16
gi|21536294 claudin 14 [Homo sapiens]                                  84   1e-16
gi|225703138 claudin 14 [Homo sapiens]                                 84   1e-16
gi|6912314 claudin 14 [Homo sapiens]                                   84   1e-16
gi|225703140 claudin 14 [Homo sapiens]                                 84   1e-16
gi|153792768 claudin 6 [Homo sapiens]                                  80   1e-15
gi|4502877 claudin 4 [Homo sapiens]                                    78   5e-15
gi|169167239 PREDICTED: claudin-24-like [Homo sapiens]                 77   1e-14
gi|169166931 PREDICTED: claudin-24-like [Homo sapiens]                 77   1e-14
gi|40788011 claudin 8 [Homo sapiens]                                   75   3e-14
gi|169166402 PREDICTED: claudin-24-like [Homo sapiens]                 75   5e-14
gi|9966781 claudin 2 [Homo sapiens]                                    72   3e-13
gi|231569235 claudin 10 isoform a_i1 [Homo sapiens]                    70   1e-12
gi|47716519 claudin 20 [Homo sapiens]                                  70   2e-12
gi|5729970 claudin 16 [Homo sapiens]                                   69   3e-12
gi|6912316 claudin 17 [Homo sapiens]                                   69   4e-12

>gi|10938016 claudin 11 [Homo sapiens]
          Length = 207

 Score =  427 bits (1098), Expect = e-120
 Identities = 207/207 (100%), Positives = 207/207 (100%)

Query: 1   MVATCLQVVGFVTSFVGWIGVIVTTSTNDWVVTCGYTIPTCRKLDELGSKGLWADCVMAT 60
           MVATCLQVVGFVTSFVGWIGVIVTTSTNDWVVTCGYTIPTCRKLDELGSKGLWADCVMAT
Sbjct: 1   MVATCLQVVGFVTSFVGWIGVIVTTSTNDWVVTCGYTIPTCRKLDELGSKGLWADCVMAT 60

Query: 61  GLYHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKYRRA 120
           GLYHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKYRRA
Sbjct: 61  GLYHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKYRRA 120

Query: 121 QLAGVLLILLALCALVATIWFPVCAHRETTIVSFGYSLYAGWIGAVLCLVGGCVILCCAG 180
           QLAGVLLILLALCALVATIWFPVCAHRETTIVSFGYSLYAGWIGAVLCLVGGCVILCCAG
Sbjct: 121 QLAGVLLILLALCALVATIWFPVCAHRETTIVSFGYSLYAGWIGAVLCLVGGCVILCCAG 180

Query: 181 DAQAFGENRFYYTAGSSSPTHAKSAHV 207
           DAQAFGENRFYYTAGSSSPTHAKSAHV
Sbjct: 181 DAQAFGENRFYYTAGSSSPTHAKSAHV 207


>gi|10863887 claudin 1 [Homo sapiens]
          Length = 211

 Score =  110 bits (276), Expect = 6e-25
 Identities = 69/190 (36%), Positives = 100/190 (52%), Gaps = 26/190 (13%)

Query: 6   LQVVGFVTSFVGWIGVIVTTSTNDWVVT--CGYTIPTCRKLDELGSKGLWADCV-MATGL 62
           LQ++GF+ +F+GWIG IV+T+   W +    G  I T + + E    GLW  CV  +TG 
Sbjct: 6   LQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYE----GLWMSCVSQSTGQ 61

Query: 63  YHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKYRRAQL 122
             CK    +L L   +QA RALM+   +LG+ AI +    + C++  ++  V K R A +
Sbjct: 62  IQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAVI 121

Query: 123 AGVLLILLALCALVATIWF-------------PVCAHRETTIVSFGYSLYAGWIGAVLCL 169
            G + +L  L  LVAT W+             PV A  E     FG +L+ GW  A LCL
Sbjct: 122 GGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYE-----FGQALFTGWAAASLCL 176

Query: 170 VGGCVILCCA 179
           +GG  +LCC+
Sbjct: 177 LGG-ALLCCS 185


>gi|183979973 claudin 19 isoform a [Homo sapiens]
          Length = 224

 Score =  105 bits (261), Expect = 4e-23
 Identities = 68/209 (32%), Positives = 104/209 (49%), Gaps = 15/209 (7%)

Query: 1   MVATCLQVVGFVTSFVGWIGVIVTTSTNDWVVT--CGYTIPTCRKLDELGSKGLWADCV- 57
           M  + LQ++G+  +  GW+G+I +T+   W  +   G  I T   L E    GLW  C  
Sbjct: 1   MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYE----GLWMSCAS 56

Query: 58  MATGLYHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKY 117
            +TG   CK    +L L G++Q+ RALM+ A +LG  A++L +  + C R+G    +AK 
Sbjct: 57  QSTGQVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKG 116

Query: 118 RRAQLAGVLLILLALCALVATIWFPVCAHRE----TTIVS----FGYSLYAGWIGAVLCL 169
           R A   G L IL  LC L A  W+     +E    +T V+    FG +L+ GW  A L +
Sbjct: 117 RVAIAGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAV 176

Query: 170 VGGCVILCCAGDAQAFGENRFYYTAGSSS 198
           +GG  + C   + +    +   Y  G S+
Sbjct: 177 LGGSFLCCTCPEPERPNSSPQPYRPGPSA 205


>gi|183979975 claudin 19 isoform b [Homo sapiens]
          Length = 211

 Score =  105 bits (261), Expect = 4e-23
 Identities = 68/209 (32%), Positives = 104/209 (49%), Gaps = 15/209 (7%)

Query: 1   MVATCLQVVGFVTSFVGWIGVIVTTSTNDWVVT--CGYTIPTCRKLDELGSKGLWADCV- 57
           M  + LQ++G+  +  GW+G+I +T+   W  +   G  I T   L E    GLW  C  
Sbjct: 1   MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYE----GLWMSCAS 56

Query: 58  MATGLYHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKY 117
            +TG   CK    +L L G++Q+ RALM+ A +LG  A++L +  + C R+G    +AK 
Sbjct: 57  QSTGQVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKG 116

Query: 118 RRAQLAGVLLILLALCALVATIWFPVCAHRE----TTIVS----FGYSLYAGWIGAVLCL 169
           R A   G L IL  LC L A  W+     +E    +T V+    FG +L+ GW  A L +
Sbjct: 117 RVAIAGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAV 176

Query: 170 VGGCVILCCAGDAQAFGENRFYYTAGSSS 198
           +GG  + C   + +    +   Y  G S+
Sbjct: 177 LGGSFLCCTCPEPERPNSSPQPYRPGPSA 205


>gi|153792186 claudin 7 [Homo sapiens]
          Length = 211

 Score =  103 bits (257), Expect = 1e-22
 Identities = 65/201 (32%), Positives = 102/201 (50%), Gaps = 22/201 (10%)

Query: 1   MVATCLQVVGFVTSFVGWIGVIVTTSTNDWVVT--CGYTIPTCRKLDELGSKGLWADCV- 57
           M  + LQ++GF  + +GW+G++  T+   W ++   G  I T + +     KGLW DCV 
Sbjct: 1   MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAM----YKGLWMDCVT 56

Query: 58  MATGLYHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKY 117
            +TG+  CK    +L L   +QA RALM+ + VLG  A+ +    + C R G +  V K 
Sbjct: 57  QSTGMMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKA 116

Query: 118 RRAQLAGVLLILLALCALVATIWFPVCAHRETT-----------IVSFGYSLYAGWIGAV 166
           R A   G++ I+  L ALVA  W+    H+  T              FG +++ GW G+ 
Sbjct: 117 RIAMGGGIIFIVAGLAALVACSWY---GHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSA 173

Query: 167 LCLVGGCVILC-CAGDAQAFG 186
           L ++GG ++ C C G+    G
Sbjct: 174 LVILGGALLSCSCPGNESKAG 194


>gi|50345279 claudin 18 isoform 2 [Homo sapiens]
          Length = 261

 Score = 95.1 bits (235), Expect = 4e-20
 Identities = 68/221 (30%), Positives = 97/221 (43%), Gaps = 28/221 (12%)

Query: 1   MVATCLQVVGFVTSFVGWIGVIVTTSTNDWVVTCGYTIPTCRKLDELGSKGLWADCVM-A 59
           M  T  Q +GFV S +G  G+I  T  + W     Y  P     +    +GLW  CV  +
Sbjct: 1   MAVTACQGLGFVVSLIGIAGIIAATCMDQWSTQDLYNNPVTAVFNY---QGLWRSCVRES 57

Query: 60  TGLYHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKYRR 119
           +G   C+    +L LP  +QA RALMI   VLG   +L+ +  L CIR+G     AK   
Sbjct: 58  SGFTECRGYFTLLGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANM 117

Query: 120 AQLAGVLLILLALCA----------LVATIWFPVC---------AHRETTIVSFGYSLYA 160
              +G++ I+  LCA          LV   W                  T  +FG +L+ 
Sbjct: 118 TLTSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFV 177

Query: 161 GWIGAVLCLVGGCVILCCAGDAQAFGENRF----YYTAGSS 197
           GW+   L L+GG V++C A    A  E  +    Y+ +G S
Sbjct: 178 GWVAGGLTLIGG-VMMCIACRGLAPEETNYKAVSYHASGHS 217


>gi|7705961 claudin 18 isoform 1 [Homo sapiens]
          Length = 261

 Score = 95.1 bits (235), Expect = 4e-20
 Identities = 70/221 (31%), Positives = 96/221 (43%), Gaps = 28/221 (12%)

Query: 1   MVATCLQVVGFVTSFVGWIGVIVTTSTNDWVVTCGYTIPTCRKLDELGSKGLWADCV-MA 59
           M  T  QVV F+ S +G  G I  T  + W     Y  P          +GLW  CV  +
Sbjct: 1   MSTTTCQVVAFLLSILGLAGCIAATGMDMWSTQDLYDNPVTSVFQY---EGLWRSCVRQS 57

Query: 60  TGLYHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKYRR 119
           +G   C+P   IL LP  +QA RALMI   VLG   +L+ +  L CIR+G     AK   
Sbjct: 58  SGFTECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANM 117

Query: 120 AQLAGVLLILLALCA----------LVATIWFPVC---------AHRETTIVSFGYSLYA 160
              +G++ I+  LCA          LV   W                  T  +FG +L+ 
Sbjct: 118 TLTSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFV 177

Query: 161 GWIGAVLCLVGGCVILCCAGDAQAFGENRF----YYTAGSS 197
           GW+   L L+GG V++C A    A  E  +    Y+ +G S
Sbjct: 178 GWVAGGLTLIGG-VMMCIACRGLAPEETNYKAVSYHASGHS 217


>gi|5921465 claudin 10 isoform b [Homo sapiens]
          Length = 228

 Score = 93.6 bits (231), Expect = 1e-19
 Identities = 66/190 (34%), Positives = 95/190 (50%), Gaps = 23/190 (12%)

Query: 1   MVATCLQVVGFVTSFVGWIGVIVTTSTNDWVVTC--GYTIPTCRKLDELGSKGLWADCVM 58
           M +T  +++ F+ S  GW+ V  T  T+ W V+   G  I T           LW  CV 
Sbjct: 1   MASTASEIIAFMVSISGWVLVSSTLPTDYWKVSTIDGTVITTATYW-----ANLWKACVT 55

Query: 59  -ATGLYHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKY 117
            +TG+ +CK    +L L GY+QACR LMIAA  LG    +  L  + C ++G     AK 
Sbjct: 56  DSTGVSNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDK-AKA 114

Query: 118 RRAQLAGVLLILLALCALVATIWFPVCAHRETTIV----------SFGYSLYAGWIGAVL 167
           + A LAG++ IL  LC++     +   A++ TT              G +L+ GW GA L
Sbjct: 115 KIACLAGIVFILSGLCSMTGCSLY---ANKITTEFFDPLFVEQKYELGAALFIGWAGASL 171

Query: 168 CLVGGCVILC 177
           C++GG VI C
Sbjct: 172 CIIGG-VIFC 180


>gi|195947374 claudin 5 [Homo sapiens]
          Length = 303

 Score = 93.6 bits (231), Expect = 1e-19
 Identities = 67/189 (35%), Positives = 88/189 (46%), Gaps = 17/189 (8%)

Query: 1   MVATCLQVVGFVTSFVGWIGVIVTTSTNDWVVTC--GYTIPTCRKLDELGSKGLWADCVM 58
           M +  L+++G V   VGW G+I+      W VT    + I T +       KGLW  CV+
Sbjct: 86  MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTT----WKGLWMSCVV 141

Query: 59  -ATGLYHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKY 117
            +TG   CK    +L L   VQA RAL ++A +L   A+ + L    C      PG AK 
Sbjct: 142 QSTGHMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTC-VAPGPAKA 200

Query: 118 RRAQLAGVLLILLALCALVATIWFPVCAHRE--------TTIVSFGYSLYAGWIGAVLCL 169
           R A   GVL +   L ALV   WF     RE        +     G +LY GW    L +
Sbjct: 201 RVALTGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLM 260

Query: 170 VGGCVILCC 178
           VGGC +LCC
Sbjct: 261 VGGC-LLCC 268


>gi|195947372 claudin 5 [Homo sapiens]
          Length = 303

 Score = 93.6 bits (231), Expect = 1e-19
 Identities = 67/189 (35%), Positives = 88/189 (46%), Gaps = 17/189 (8%)

Query: 1   MVATCLQVVGFVTSFVGWIGVIVTTSTNDWVVTC--GYTIPTCRKLDELGSKGLWADCVM 58
           M +  L+++G V   VGW G+I+      W VT    + I T +       KGLW  CV+
Sbjct: 86  MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTT----WKGLWMSCVV 141

Query: 59  -ATGLYHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKY 117
            +TG   CK    +L L   VQA RAL ++A +L   A+ + L    C      PG AK 
Sbjct: 142 QSTGHMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTC-VAPGPAKA 200

Query: 118 RRAQLAGVLLILLALCALVATIWFPVCAHRE--------TTIVSFGYSLYAGWIGAVLCL 169
           R A   GVL +   L ALV   WF     RE        +     G +LY GW    L +
Sbjct: 201 RVALTGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLM 260

Query: 170 VGGCVILCC 178
           VGGC +LCC
Sbjct: 261 VGGC-LLCC 268


>gi|7656981 claudin 15 [Homo sapiens]
          Length = 228

 Score = 90.1 bits (222), Expect = 1e-18
 Identities = 64/205 (31%), Positives = 94/205 (45%), Gaps = 16/205 (7%)

Query: 2   VATCLQVVGFVTSFVGWIGVIVTTSTNDW-VVTCGYTIPTCRKLDELGSKGLWADCVM-A 59
           ++  ++  GF  + VG + + VT   + W V T    + T   + E     LW  C   +
Sbjct: 1   MSMAVETFGFFMATVGLLMLGVTLPNSYWRVSTVHGNVITTNTIFE----NLWFSCATDS 56

Query: 60  TGLYHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKYRR 119
            G+Y+C     +L L GY+QACRALMI A +LG   +LL +  L C  +G      K + 
Sbjct: 57  LGVYNCWEFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKL 116

Query: 120 AQLAGVLLILLALCALVATIWFPVCAHRE-------TTIVSFGYSLYAGWIGAVLCLVGG 172
           A  AG L IL  +C +VA  W+     R+        T    G +LY GW  +++ ++GG
Sbjct: 117 AATAGALHILAGICGMVAISWYAFNITRDFFDPLYPGTKYELGPALYLGWSASLISILGG 176

Query: 173 ---CVILCCAGDAQAFGENRFYYTA 194
              C   CC  D       R  Y A
Sbjct: 177 LCLCSACCCGSDEDPAASARRPYQA 201


>gi|11141861 claudin 9 [Homo sapiens]
          Length = 217

 Score = 89.7 bits (221), Expect = 2e-18
 Identities = 64/191 (33%), Positives = 96/191 (50%), Gaps = 21/191 (10%)

Query: 1   MVATCLQVVGFVTSFVGWIGVIVTTSTNDWVVTC--GYTIPTCRKLDELGSKGLWADCVM 58
           M +T L+++G   + +GW+G +V+ +   W VT   G +I   + + E    GLW  CV+
Sbjct: 1   MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWE----GLWMSCVV 56

Query: 59  -ATGLYHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKY 117
            +TG   CK    +L LP  +QA RAL + A +L L  +L+ +T   C    ++ G AK 
Sbjct: 57  QSTGQMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEG-AKA 115

Query: 118 RRAQLAGVLLILLALCALVATIWF----------PVCAHRETTIVSFGYSLYAGWIGAVL 167
           R    AGV+L+L  +  L+   W           P+ A  E      G SLY GW  A L
Sbjct: 116 RIVLTAGVILLLAGILVLIPVCWTAHAIIQDFYNPLVA--EALKRELGASLYLGWAAAAL 173

Query: 168 CLVGGCVILCC 178
            ++GG  +LCC
Sbjct: 174 LMLGG-GLLCC 183


>gi|33598916 claudin 10 isoform a [Homo sapiens]
          Length = 226

 Score = 88.2 bits (217), Expect = 4e-18
 Identities = 61/183 (33%), Positives = 94/183 (51%), Gaps = 21/183 (11%)

Query: 7   QVVGFVTSFVGWIGVIVTTSTNDWVVTC-GYTIPTCRKLDELGSKGLWADCV-MATGLYH 64
           Q+   V+   G+  ++  T++N+W VT    ++ T   + +    GLW +C   A G +H
Sbjct: 5   QIWALVSGVGGFGALVAATTSNEWKVTTRASSVITATWVYQ----GLWMNCAGNALGSFH 60

Query: 65  CKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKYRRAQLAG 124
           C+P   I  + GY+QACR LMIAA  LG    +  L  + C ++G     AK + A LAG
Sbjct: 61  CRPHFTIFKVAGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGS-DKAKAKIACLAG 119

Query: 125 VLLILLALCALVATIWFPVCAHRETT----------IVSFGYSLYAGWIGAVLCLVGGCV 174
           ++ IL  LC++     +   A++ TT              G +L+ GW GA LC++GG V
Sbjct: 120 IVFILSGLCSMTGCSLY---ANKITTEFFDPLFVEQKYELGAALFIGWAGASLCIIGG-V 175

Query: 175 ILC 177
           I C
Sbjct: 176 IFC 178


>gi|4502875 claudin 3 [Homo sapiens]
          Length = 220

 Score = 86.3 bits (212), Expect = 2e-17
 Identities = 65/205 (31%), Positives = 96/205 (46%), Gaps = 17/205 (8%)

Query: 6   LQVVGFVTSFVGWIGVIVTTSTNDWVVTC--GYTIPTCRKLDELGSKGLWADCVM-ATGL 62
           L++ G   + +GW+G IV  +   W V+   G  I T + + E    GLW +CV+ +TG 
Sbjct: 5   LEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWE----GLWMNCVVQSTGQ 60

Query: 63  YHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKYRRAQL 122
             CK    +L LP  +QA RAL++ A +L    +L+ L    C    Q+   AK +   +
Sbjct: 61  MQCKVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQD-DTAKAKITIV 119

Query: 123 AGVLLILLALCALVATIWFPVCAHR--------ETTIVSFGYSLYAGWIGAVLCLVGGCV 174
           AGVL +L AL  LV   W      R        E      G  LY GW  A L L+GG +
Sbjct: 120 AGVLFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGAL 179

Query: 175 ILC-CAGDAQAFGENRFYYTAGSSS 198
           + C C    + +   +  Y+A  S+
Sbjct: 180 LCCSCPPREKKYTATKVVYSAPRST 204


>gi|225703142 claudin 14 [Homo sapiens]
          Length = 239

 Score = 83.6 bits (205), Expect = 1e-16
 Identities = 62/192 (32%), Positives = 95/192 (49%), Gaps = 13/192 (6%)

Query: 1   MVATCLQVVGFVTSFVGWIGVIVTTSTNDWVVTCGYTIPTCRKLDELGSKGLWADCVM-A 59
           M +T +Q++GF+ SF+G +G ++TT    W  T          +  L  KGLW +CV  +
Sbjct: 1   MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYL--KGLWMECVWHS 58

Query: 60  TGLYHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKYRR 119
           TG+Y C+    +L LP  +QA RALM+ + +L   A    +  + C R  +    AK   
Sbjct: 59  TGIYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGT-PAKTTF 117

Query: 120 AQLAGVLLILLALCALVATIWF--PVCAHRETTIV------SFGYSLYAGWIGAVLCLVG 171
           A L G L IL  L  +VA  W    V  +    ++        G +LY G+I + L L+G
Sbjct: 118 AILGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIG 177

Query: 172 GCVI-LCCAGDA 182
           G ++ L C  +A
Sbjct: 178 GTLLCLSCQDEA 189


>gi|21536294 claudin 14 [Homo sapiens]
          Length = 239

 Score = 83.6 bits (205), Expect = 1e-16
 Identities = 62/192 (32%), Positives = 95/192 (49%), Gaps = 13/192 (6%)

Query: 1   MVATCLQVVGFVTSFVGWIGVIVTTSTNDWVVTCGYTIPTCRKLDELGSKGLWADCVM-A 59
           M +T +Q++GF+ SF+G +G ++TT    W  T          +  L  KGLW +CV  +
Sbjct: 1   MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYL--KGLWMECVWHS 58

Query: 60  TGLYHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKYRR 119
           TG+Y C+    +L LP  +QA RALM+ + +L   A    +  + C R  +    AK   
Sbjct: 59  TGIYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGT-PAKTTF 117

Query: 120 AQLAGVLLILLALCALVATIWF--PVCAHRETTIV------SFGYSLYAGWIGAVLCLVG 171
           A L G L IL  L  +VA  W    V  +    ++        G +LY G+I + L L+G
Sbjct: 118 AILGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIG 177

Query: 172 GCVI-LCCAGDA 182
           G ++ L C  +A
Sbjct: 178 GTLLCLSCQDEA 189


>gi|225703138 claudin 14 [Homo sapiens]
          Length = 239

 Score = 83.6 bits (205), Expect = 1e-16
 Identities = 62/192 (32%), Positives = 95/192 (49%), Gaps = 13/192 (6%)

Query: 1   MVATCLQVVGFVTSFVGWIGVIVTTSTNDWVVTCGYTIPTCRKLDELGSKGLWADCVM-A 59
           M +T +Q++GF+ SF+G +G ++TT    W  T          +  L  KGLW +CV  +
Sbjct: 1   MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYL--KGLWMECVWHS 58

Query: 60  TGLYHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKYRR 119
           TG+Y C+    +L LP  +QA RALM+ + +L   A    +  + C R  +    AK   
Sbjct: 59  TGIYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGT-PAKTTF 117

Query: 120 AQLAGVLLILLALCALVATIWF--PVCAHRETTIV------SFGYSLYAGWIGAVLCLVG 171
           A L G L IL  L  +VA  W    V  +    ++        G +LY G+I + L L+G
Sbjct: 118 AILGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIG 177

Query: 172 GCVI-LCCAGDA 182
           G ++ L C  +A
Sbjct: 178 GTLLCLSCQDEA 189


>gi|6912314 claudin 14 [Homo sapiens]
          Length = 239

 Score = 83.6 bits (205), Expect = 1e-16
 Identities = 62/192 (32%), Positives = 95/192 (49%), Gaps = 13/192 (6%)

Query: 1   MVATCLQVVGFVTSFVGWIGVIVTTSTNDWVVTCGYTIPTCRKLDELGSKGLWADCVM-A 59
           M +T +Q++GF+ SF+G +G ++TT    W  T          +  L  KGLW +CV  +
Sbjct: 1   MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYL--KGLWMECVWHS 58

Query: 60  TGLYHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKYRR 119
           TG+Y C+    +L LP  +QA RALM+ + +L   A    +  + C R  +    AK   
Sbjct: 59  TGIYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGT-PAKTTF 117

Query: 120 AQLAGVLLILLALCALVATIWF--PVCAHRETTIV------SFGYSLYAGWIGAVLCLVG 171
           A L G L IL  L  +VA  W    V  +    ++        G +LY G+I + L L+G
Sbjct: 118 AILGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIG 177

Query: 172 GCVI-LCCAGDA 182
           G ++ L C  +A
Sbjct: 178 GTLLCLSCQDEA 189


>gi|225703140 claudin 14 [Homo sapiens]
          Length = 239

 Score = 83.6 bits (205), Expect = 1e-16
 Identities = 62/192 (32%), Positives = 95/192 (49%), Gaps = 13/192 (6%)

Query: 1   MVATCLQVVGFVTSFVGWIGVIVTTSTNDWVVTCGYTIPTCRKLDELGSKGLWADCVM-A 59
           M +T +Q++GF+ SF+G +G ++TT    W  T          +  L  KGLW +CV  +
Sbjct: 1   MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYL--KGLWMECVWHS 58

Query: 60  TGLYHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKYRR 119
           TG+Y C+    +L LP  +QA RALM+ + +L   A    +  + C R  +    AK   
Sbjct: 59  TGIYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGT-PAKTTF 117

Query: 120 AQLAGVLLILLALCALVATIWF--PVCAHRETTIV------SFGYSLYAGWIGAVLCLVG 171
           A L G L IL  L  +VA  W    V  +    ++        G +LY G+I + L L+G
Sbjct: 118 AILGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIG 177

Query: 172 GCVI-LCCAGDA 182
           G ++ L C  +A
Sbjct: 178 GTLLCLSCQDEA 189


>gi|153792768 claudin 6 [Homo sapiens]
          Length = 220

 Score = 80.1 bits (196), Expect = 1e-15
 Identities = 57/210 (27%), Positives = 97/210 (46%), Gaps = 16/210 (7%)

Query: 1   MVATCLQVVGFVTSFVGWIGVIVTTSTNDWVVTC--GYTIPTCRKLDELGSKGLWADCVM 58
           M +  +Q++G V + +GW+  +V+ +   W VT   G +I   + + E    GLW  CV+
Sbjct: 1   MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWE----GLWMSCVV 56

Query: 59  -ATGLYHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKY 117
            +TG   CK    +L LP  +QA RAL + A ++ L  +L+ L    C    +E   +K 
Sbjct: 57  QSTGQMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKD-SKA 115

Query: 118 RRAQLAGVLLILLALCALVATIWFPVCAHR--------ETTIVSFGYSLYAGWIGAVLCL 169
           R    +G++ ++  +  L+   W      R        E      G SLY GW  + L L
Sbjct: 116 RLVLTSGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLL 175

Query: 170 VGGCVILCCAGDAQAFGENRFYYTAGSSSP 199
           +GG ++ C      + G + +     +S+P
Sbjct: 176 LGGGLLCCTCPSGGSQGPSHYMARYSTSAP 205


>gi|4502877 claudin 4 [Homo sapiens]
          Length = 209

 Score = 78.2 bits (191), Expect = 5e-15
 Identities = 60/191 (31%), Positives = 93/191 (48%), Gaps = 21/191 (10%)

Query: 1   MVATCLQVVGFVTSFVGWIGVIVTTSTNDWVVTC--GYTIPTCRKLDELGSKGLWADCVM 58
           M +  LQV+G   + +GW+ V++  +   W VT   G  I T + + E    GLW +CV+
Sbjct: 1   MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWE----GLWMNCVV 56

Query: 59  -ATGLYHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKY 117
            +TG   CK    +L LP  +QA RAL+I + ++    +LL +    C    ++   AK 
Sbjct: 57  QSTGQMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDES-AKA 115

Query: 118 RRAQLAGVLLILLALCALVATIWF----------PVCAHRETTIVSFGYSLYAGWIGAVL 167
           +   +AGV+ +L  L  +V   W           P+ A  +      G SLY GW  + L
Sbjct: 116 KTMIVAGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKR--EMGASLYVGWAASGL 173

Query: 168 CLVGGCVILCC 178
            L+GG  +LCC
Sbjct: 174 LLLGG-GLLCC 183


>gi|169167239 PREDICTED: claudin-24-like [Homo sapiens]
          Length = 220

 Score = 77.0 bits (188), Expect = 1e-14
 Identities = 57/194 (29%), Positives = 84/194 (43%), Gaps = 21/194 (10%)

Query: 4   TCLQVVGFVTSFVGWIGVIVTTSTNDWVVTCGYTIPTCRKLDELGSKGLWADCVMATGL- 62
           T +Q VG + SF+GWI  I+TT    W       +       E  + GLW  CV+   + 
Sbjct: 7   TAMQSVGLLLSFLGWILSIITTYLPHWK-----NLNLDLNEMENWTMGLWQTCVIQEEVG 61

Query: 63  YHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKYRRAQL 122
             CK     L LP  ++  R LM  ++ LG   +L+    L C+R+G+     K R   L
Sbjct: 62  MQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLIL 121

Query: 123 AGVLLILLALCALVATIWFPVCAHRETTIV------------SFGYSLYAGWIGAVLCLV 170
            G+L     + ALV   W    AH+                  FG +L+ GW   +  L+
Sbjct: 122 GGILSWASGITALVPVSW---VAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLL 178

Query: 171 GGCVILCCAGDAQA 184
           GGC++ C A  + A
Sbjct: 179 GGCLLNCAACSSHA 192


>gi|169166931 PREDICTED: claudin-24-like [Homo sapiens]
          Length = 220

 Score = 77.0 bits (188), Expect = 1e-14
 Identities = 57/194 (29%), Positives = 84/194 (43%), Gaps = 21/194 (10%)

Query: 4   TCLQVVGFVTSFVGWIGVIVTTSTNDWVVTCGYTIPTCRKLDELGSKGLWADCVMATGL- 62
           T +Q VG + SF+GWI  I+TT    W       +       E  + GLW  CV+   + 
Sbjct: 7   TAMQSVGLLLSFLGWILSIITTYLPHWK-----NLNLDLNEMENWTMGLWQTCVIQEEVG 61

Query: 63  YHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKYRRAQL 122
             CK     L LP  ++  R LM  ++ LG   +L+    L C+R+G+     K R   L
Sbjct: 62  MQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLIL 121

Query: 123 AGVLLILLALCALVATIWFPVCAHRETTIV------------SFGYSLYAGWIGAVLCLV 170
            G+L     + ALV   W    AH+                  FG +L+ GW   +  L+
Sbjct: 122 GGILSWASGITALVPVSW---VAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLL 178

Query: 171 GGCVILCCAGDAQA 184
           GGC++ C A  + A
Sbjct: 179 GGCLLNCAACSSHA 192


>gi|40788011 claudin 8 [Homo sapiens]
          Length = 225

 Score = 75.5 bits (184), Expect = 3e-14
 Identities = 58/227 (25%), Positives = 97/227 (42%), Gaps = 22/227 (9%)

Query: 1   MVATCLQVVGFVTSFVGWIGVIVTTSTNDWVVTCGYTIPTCRKLDELGSKGLWADCVMAT 60
           M    L++ G     VG +G +  T    W V+    I     + E   +GLW +CV   
Sbjct: 1   MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSA--FIENNIVVFENFWEGLWMNCVRQA 58

Query: 61  GL-YHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKYRR 119
            +   CK    +L L   +QA R LM AASV+   A ++ +  + C R   +    K   
Sbjct: 59  NIRMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHI 118

Query: 120 AQLAGVLLILLALCALVATIWFPVCAHRE--TTIVS------FGYSLYAGWIGAVLCLVG 171
              AG++ I+  +  L+   W      R+   +IV+       G +LY GW  A++ +VG
Sbjct: 119 LLTAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVG 178

Query: 172 G---CVILCCAGDAQAF--------GENRFYYTAGSSSPTHAKSAHV 207
           G   C + CC   + ++           + Y+T   S   +++S +V
Sbjct: 179 GALFCCVFCCNEKSSSYRYSIPSHRTTQKSYHTGKKSPSVYSRSQYV 225


>gi|169166402 PREDICTED: claudin-24-like [Homo sapiens]
          Length = 220

 Score = 74.7 bits (182), Expect = 5e-14
 Identities = 56/194 (28%), Positives = 83/194 (42%), Gaps = 21/194 (10%)

Query: 4   TCLQVVGFVTSFVGWIGVIVTTSTNDWVVTCGYTIPTCRKLDELGSKGLWADCVMATGL- 62
           T +Q VG + S +GWI  I+TT    W       +       E  + GLW  CV+   + 
Sbjct: 7   TAMQSVGLLLSLLGWILSIITTYLPHWK-----NLNLDLNEMENWTMGLWQTCVIQEEVG 61

Query: 63  YHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKYRRAQL 122
             CK     L LP  ++  R LM  ++ LG   +L+    L C+R+G+     K R   L
Sbjct: 62  MQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLIL 121

Query: 123 AGVLLILLALCALVATIWFPVCAHRETTIV------------SFGYSLYAGWIGAVLCLV 170
            G+L     + ALV   W    AH+                  FG +L+ GW   +  L+
Sbjct: 122 GGILSWASGITALVPVSW---VAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLL 178

Query: 171 GGCVILCCAGDAQA 184
           GGC++ C A  + A
Sbjct: 179 GGCLLNCAACSSHA 192


>gi|9966781 claudin 2 [Homo sapiens]
          Length = 230

 Score = 72.0 bits (175), Expect = 3e-13
 Identities = 61/216 (28%), Positives = 97/216 (44%), Gaps = 19/216 (8%)

Query: 1   MVATCLQVVGFVTSFVGWIGVIVTTSTNDWVVTC--GYTIPTCRKLDELGSKGLWADCVM 58
           M +  LQ+VG++   +G +G +V      W  +   G +I T        SKGLW +C  
Sbjct: 1   MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGF----SKGLWMECAT 56

Query: 59  -ATGLYHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKY 117
            +TG+  C     +L LP  +QA +A+M+ +S +   A ++ +  + C    QE   AK 
Sbjct: 57  HSTGITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQE-SRAKD 115

Query: 118 RRAQLAGVLLILLALCALVATIW--------FPVCAHRETTIVSFGYSLYAGWIGAVLCL 169
           R A   GV  IL  L   +   W        F      ++     G +LY G I ++  L
Sbjct: 116 RVAVAGGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSL 175

Query: 170 VGGCVILCCAGDAQAFGENRFYYTAGSSSPTHAKSA 205
           + G +ILC +  +Q    N  YY A  + P   +S+
Sbjct: 176 IAG-IILCFSCSSQRNRSN--YYDAYQAQPLATRSS 208


>gi|231569235 claudin 10 isoform a_i1 [Homo sapiens]
          Length = 207

 Score = 70.1 bits (170), Expect = 1e-12
 Identities = 55/182 (30%), Positives = 85/182 (46%), Gaps = 38/182 (20%)

Query: 7   QVVGFVTSFVGWIGVIVTTSTNDWVVTC-GYTIPTCRKLDELGSKGLWADCVMATGLYHC 65
           Q+   V+   G+  ++  T++N+W VT    ++ T   + +    GLW +C         
Sbjct: 5   QIWALVSGVGGFGALVAATTSNEWKVTTRASSVITATWVYQ----GLWMNCA-------- 52

Query: 66  KPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKYRRAQLAGV 125
                     GY+QACR LMIAA  LG    +  L  + C ++G     AK + A LAG+
Sbjct: 53  ----------GYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGS-DKAKAKIACLAGI 101

Query: 126 LLILLALCALVATIWFPVCAHRETT----------IVSFGYSLYAGWIGAVLCLVGGCVI 175
           + IL  LC++     +   A++ TT              G +L+ GW GA LC++GG VI
Sbjct: 102 VFILSGLCSMTGCSLY---ANKITTEFFDPLFVEQKYELGAALFIGWAGASLCIIGG-VI 157

Query: 176 LC 177
            C
Sbjct: 158 FC 159


>gi|47716519 claudin 20 [Homo sapiens]
          Length = 219

 Score = 69.7 bits (169), Expect = 2e-12
 Identities = 50/183 (27%), Positives = 84/183 (45%), Gaps = 12/183 (6%)

Query: 1   MVATCLQVVGFVTSFVGWIGVIVTTSTNDWVVTCGYTIPTCRKLDELGSKGLWADCVM-A 59
           M +  LQ++ F+ +  G  GV+  T   +W V           + +L   GLW DC   +
Sbjct: 1   MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQL--HGLWMDCTWYS 58

Query: 60  TGLYHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKYRR 119
           TG++ C     IL LP +VQA RA M+ A VL    I      + C R+G +    K   
Sbjct: 59  TGMFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGGD-RETKSHA 117

Query: 120 AQLAGVLLILLALCALVATIWFP---VCAHRETTIVSF-----GYSLYAGWIGAVLCLVG 171
           +   GV  +   + +L++T+W+    +    + T+        G ++Y G+I A+L  + 
Sbjct: 118 SFAGGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFIS 177

Query: 172 GCV 174
           G +
Sbjct: 178 GMI 180


>gi|5729970 claudin 16 [Homo sapiens]
          Length = 305

 Score = 68.9 bits (167), Expect = 3e-12
 Identities = 55/208 (26%), Positives = 93/208 (44%), Gaps = 22/208 (10%)

Query: 1   MVATCLQVVGFVTSFVGWIG---VIVTTSTNDWVVTCGYTIPTCRKLDELGSKGLWADCV 57
           ++AT   ++ ++  F  +     +IV T T+ W+V    ++    K      +GLW +CV
Sbjct: 67  LLATMRDLLQYIACFFAFFSAGFLIVATWTDCWMVNADDSLEVSTKC-----RGLWWECV 121

Query: 58  MAT--GLYHCKPLVDILIL-PGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGV 114
                G+  C     IL   P  +   RALMI A +L     L LL  L C++   +   
Sbjct: 122 TNAFDGIRTCDEYDSILAEHPLKLVVTRALMITADILAGFGFLTLLLGLDCVKFLPDEPY 181

Query: 115 AKYRRAQLAGVLLILLALCALVATIWFPVCAHRE-TTIV----------SFGYSLYAGWI 163
            K R   +AG  L++     ++ ++W+ V  + E +T+V           FG+S + G  
Sbjct: 182 IKVRICFVAGATLLIAGTPGIIGSVWYAVDVYVERSTLVLHNIFLGIQYKFGWSCWLGMA 241

Query: 164 GAVLCLVGGCVILCCAGDAQAFGENRFY 191
           G++ C + G V+ CC    +  G  R Y
Sbjct: 242 GSLGCFLAGAVLTCCLYLFKDVGPERNY 269


>gi|6912316 claudin 17 [Homo sapiens]
          Length = 224

 Score = 68.6 bits (166), Expect = 4e-12
 Identities = 55/194 (28%), Positives = 82/194 (42%), Gaps = 18/194 (9%)

Query: 6   LQVVGFVTSFVGWIGVIVTTSTNDWVVTC--GYTIPTCRKLDELGSKGLWADCV-MATGL 62
           LQ+ G V  F+G +G + TT    W V+   G  I    +L E    GLW +C+  A   
Sbjct: 6   LQIAGLVLGFLGMVGTLATTLLPQWRVSAFVGSNIIVFERLWE----GLWMNCIRQARVR 61

Query: 63  YHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKYRRAQL 122
             CK    +L LP  ++  RALM  A  L L A+L+ +  +  ++       AK      
Sbjct: 62  LQCKFYSSLLALPPALETARALMCVAVALSLIALLIGICGMKQVQCTGSNERAKAYLLGT 121

Query: 123 AGVLLILLALCALVATIWFPVCAHRETTIVS--------FGYSLYAGWIGAVLCLVGG-- 172
           +GVL IL  +  L+   W      R+    +         G +L+ GW  A +  +GG  
Sbjct: 122 SGVLFILTGIFVLIPVSWTANIIIRDFYNPAIHIGQKRELGAALFLGWASAAVLFIGGGL 181

Query: 173 -CVILCCAGDAQAF 185
            C   CC    Q +
Sbjct: 182 LCGFCCCNRKKQGY 195


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.329    0.141    0.468 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,806,994
Number of Sequences: 37866
Number of extensions: 311781
Number of successful extensions: 936
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 44
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 826
Number of HSP's gapped (non-prelim): 65
length of query: 207
length of database: 18,247,518
effective HSP length: 98
effective length of query: 109
effective length of database: 14,536,650
effective search space: 1584494850
effective search space used: 1584494850
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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