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Search of human proteins with 142976638
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|142976638 sine oculis homeobox homolog 4 [Homo sapiens]
(781 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|142976638 sine oculis homeobox homolog 4 [Homo sapiens] 1520 0.0
gi|40354216 sine oculis homeobox homolog 5 [Homo sapiens] 313 5e-85
gi|5174681 SIX homeobox 1 [Homo sapiens] 273 6e-73
gi|219275578 SIX homeobox 2 [Homo sapiens] 261 1e-69
gi|186910311 SIX homeobox 6 [Homo sapiens] 229 1e-59
gi|4885597 sine oculis homeobox homolog 3 [Homo sapiens] 224 3e-58
gi|91982772 mucin 17 [Homo sapiens] 57 7e-08
gi|239749213 PREDICTED: mucin 3B, cell surface associated, parti... 54 7e-07
gi|197100900 iroquois homeobox 2 [Homo sapiens] 53 1e-06
gi|39930475 iroquois homeobox 2 [Homo sapiens] 53 1e-06
gi|11386181 H2.0-like homeobox [Homo sapiens] 52 2e-06
gi|57863281 Meis1, myeloid ecotropic viral integration site 1 ho... 51 4e-06
gi|7705555 iroquois homeobox 4 [Homo sapiens] 50 8e-06
gi|57863279 Meis1, myeloid ecotropic viral integration site 1 ho... 50 1e-05
gi|42476164 POU class 2 homeobox 1 [Homo sapiens] 48 3e-05
gi|51479177 iroquois homeobox protein 1 [Homo sapiens] 48 3e-05
gi|27436887 pre-B-cell leukemia homeobox 2 [Homo sapiens] 48 3e-05
gi|139394646 iroquois homeobox protein 5 [Homo sapiens] 48 4e-05
gi|4505151 Meis homeobox 1 [Homo sapiens] 47 7e-05
gi|116174748 developing brain homeobox 2 [Homo sapiens] 47 9e-05
gi|226371735 iroquois homeobox 3 [Homo sapiens] 46 1e-04
gi|210147470 NK2 transcription factor related, locus 6 [Homo sap... 46 1e-04
gi|28827782 zinc fingers and homeoboxes 3 [Homo sapiens] 46 1e-04
gi|152963644 paired-like homeodomain transcription factor 1 [Hom... 46 2e-04
gi|42544241 iroquois homeobox protein 6 [Homo sapiens] 46 2e-04
gi|21361183 paired-like homeodomain transcription factor 2 isofo... 45 2e-04
gi|24234711 paired-like homeodomain transcription factor 2 isofo... 45 2e-04
gi|24234708 paired-like homeodomain transcription factor 2 isofo... 45 2e-04
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens] 45 2e-04
gi|169168665 PREDICTED: hypothetical protein [Homo sapiens] 45 2e-04
>gi|142976638 sine oculis homeobox homolog 4 [Homo sapiens]
Length = 781
Score = 1520 bits (3936), Expect = 0.0
Identities = 781/781 (100%), Positives = 781/781 (100%)
Query: 1 MSSSSPTGQIASAADIKQENGMESASEGQEAHREVAGGAAVGLSPPAPAPFPLEPGDAAT 60
MSSSSPTGQIASAADIKQENGMESASEGQEAHREVAGGAAVGLSPPAPAPFPLEPGDAAT
Sbjct: 1 MSSSSPTGQIASAADIKQENGMESASEGQEAHREVAGGAAVGLSPPAPAPFPLEPGDAAT 60
Query: 61 AAARVSGEEGAVAAAAAGAAADQVQLHSELLGRHHHAAAAAAQTPLAFSPDHVACVCEAL 120
AAARVSGEEGAVAAAAAGAAADQVQLHSELLGRHHHAAAAAAQTPLAFSPDHVACVCEAL
Sbjct: 61 AAARVSGEEGAVAAAAAGAAADQVQLHSELLGRHHHAAAAAAQTPLAFSPDHVACVCEAL 120
Query: 121 QQGGNLDRLARFLWSLPQSDLLRGNESLLKARALVAFHQGIYPELYSILESHSFESANHP 180
QQGGNLDRLARFLWSLPQSDLLRGNESLLKARALVAFHQGIYPELYSILESHSFESANHP
Sbjct: 121 QQGGNLDRLARFLWSLPQSDLLRGNESLLKARALVAFHQGIYPELYSILESHSFESANHP 180
Query: 181 LLQQLWYKARYTEAERARGRPLGAVDKYRLRRKFPLPRTIWDGEETVYCFKEKSRNALKE 240
LLQQLWYKARYTEAERARGRPLGAVDKYRLRRKFPLPRTIWDGEETVYCFKEKSRNALKE
Sbjct: 181 LLQQLWYKARYTEAERARGRPLGAVDKYRLRRKFPLPRTIWDGEETVYCFKEKSRNALKE 240
Query: 241 LYKQNRYPSPAEKRHLAKITGLSLTQVSNWFKNRRQRDRNPSETQSKSESDGNPSTEDES 300
LYKQNRYPSPAEKRHLAKITGLSLTQVSNWFKNRRQRDRNPSETQSKSESDGNPSTEDES
Sbjct: 241 LYKQNRYPSPAEKRHLAKITGLSLTQVSNWFKNRRQRDRNPSETQSKSESDGNPSTEDES 300
Query: 301 SKGHEDLSPHPLSSSSDGITNLSLSSHMEPVYMQQIGNAKISLSSSGVLLNGSLVPASTS 360
SKGHEDLSPHPLSSSSDGITNLSLSSHMEPVYMQQIGNAKISLSSSGVLLNGSLVPASTS
Sbjct: 301 SKGHEDLSPHPLSSSSDGITNLSLSSHMEPVYMQQIGNAKISLSSSGVLLNGSLVPASTS 360
Query: 361 PVFLNGNSFIQGPSGVILNGLNVGNTQAVALNPPKMSSNIVSNGISMTDILGSTSQDVKE 420
PVFLNGNSFIQGPSGVILNGLNVGNTQAVALNPPKMSSNIVSNGISMTDILGSTSQDVKE
Sbjct: 361 PVFLNGNSFIQGPSGVILNGLNVGNTQAVALNPPKMSSNIVSNGISMTDILGSTSQDVKE 420
Query: 421 FKVLQSSANSATTTSYSPSVPVSFPGLIPSTEVKREGIQTVASQDGGSVVTFTTPVQINQ 480
FKVLQSSANSATTTSYSPSVPVSFPGLIPSTEVKREGIQTVASQDGGSVVTFTTPVQINQ
Sbjct: 421 FKVLQSSANSATTTSYSPSVPVSFPGLIPSTEVKREGIQTVASQDGGSVVTFTTPVQINQ 480
Query: 481 YGIVQIPNSGANSQFLNGSIGFSPLQLPPVSVAASQGNISVSSSTSDGSTFTSESTTVQQ 540
YGIVQIPNSGANSQFLNGSIGFSPLQLPPVSVAASQGNISVSSSTSDGSTFTSESTTVQQ
Sbjct: 481 YGIVQIPNSGANSQFLNGSIGFSPLQLPPVSVAASQGNISVSSSTSDGSTFTSESTTVQQ 540
Query: 541 GKVFLSSLAPSAVVYTVPNTGQTIGSVKQEGLERSLVFSQLMPVNQNAQVNANLSSENIS 600
GKVFLSSLAPSAVVYTVPNTGQTIGSVKQEGLERSLVFSQLMPVNQNAQVNANLSSENIS
Sbjct: 541 GKVFLSSLAPSAVVYTVPNTGQTIGSVKQEGLERSLVFSQLMPVNQNAQVNANLSSENIS 600
Query: 601 GSGLHPLASSLVNVSPTHNFSLSPSTLLNPTELNRDIADSQPMSAPVASKSTVTSVSNTN 660
GSGLHPLASSLVNVSPTHNFSLSPSTLLNPTELNRDIADSQPMSAPVASKSTVTSVSNTN
Sbjct: 601 GSGLHPLASSLVNVSPTHNFSLSPSTLLNPTELNRDIADSQPMSAPVASKSTVTSVSNTN 660
Query: 661 YATLQNCSLITGQDLLSVPMTQAALGEIVPTAEDQVGHPSPAVHQDFVQEHRLVLQSVAN 720
YATLQNCSLITGQDLLSVPMTQAALGEIVPTAEDQVGHPSPAVHQDFVQEHRLVLQSVAN
Sbjct: 661 YATLQNCSLITGQDLLSVPMTQAALGEIVPTAEDQVGHPSPAVHQDFVQEHRLVLQSVAN 720
Query: 721 MKENFLSNSESKATSSLMMLDSKSKYVLDGMVDTVCEDLETDKKELAKLQTVQLDEDMQD 780
MKENFLSNSESKATSSLMMLDSKSKYVLDGMVDTVCEDLETDKKELAKLQTVQLDEDMQD
Sbjct: 721 MKENFLSNSESKATSSLMMLDSKSKYVLDGMVDTVCEDLETDKKELAKLQTVQLDEDMQD 780
Query: 781 L 781
L
Sbjct: 781 L 781
>gi|40354216 sine oculis homeobox homolog 5 [Homo sapiens]
Length = 739
Score = 313 bits (801), Expect = 5e-85
Identities = 190/370 (51%), Positives = 232/370 (62%), Gaps = 37/370 (10%)
Query: 45 PPAPAPFPLEPGDAATAAARVSGEEGAV-------------AAAAAGAAADQVQLHSELL 91
P P+ P G+A AAA EE AAAAAGA A +E
Sbjct: 5 PAEPSAGPAAGGEAVAAAAATEEEEEEARQLLQTLQAAEGEAAAAAGAGAGAAAAGAEGP 64
Query: 92 GR-----HHHAAAAAAQTPLAFSPDHVACVCEALQQGGNLDRLARFLWSLPQSDLLRGNE 146
G AA+ T L FSP+ VACVCEAL Q G+ RL+RFL +LP ++ LRG++
Sbjct: 65 GSPGVPGSPPEAASEPPTGLRFSPEQVACVCEALLQAGHAGRLSRFLGALPPAERLRGSD 124
Query: 147 SLLKARALVAFHQGIYPELYSILESHSFESANHPLLQQLWYKARYTEAERARGRPLGAVD 206
+L+ARALVAF +G Y ELY +LES F +A+H LQ L+ +ARY EAERARGR LGAVD
Sbjct: 125 PVLRARALVAFQRGEYAELYRLLESRPFPAAHHAFLQDLYLRARYHEAERARGRALGAVD 184
Query: 207 KYRLRRKFPLPRTIWDGEETVYCFKEKSRNALKELYKQNRYPSPAEKRHLAKITGLSLTQ 266
KYRLR+KFPLP+TIWDGEETVYCFKE+SR ALK Y+ NRYP+P EKR LA +TGLSLTQ
Sbjct: 185 KYRLRKKFPLPKTIWDGEETVYCFKERSRAALKACYRGNRYPTPDEKRRLATLTGLSLTQ 244
Query: 267 VSNWFKNRRQRDRNPS--ETQSKSESDGNPSTEDESSKGHEDLSPHPLSSSSDGITNLSL 324
VSNWFKNRRQRDR + KSESDGNP+TEDESS+ EDL S++ S
Sbjct: 245 VSNWFKNRRQRDRTGAGGGAPCKSESDGNPTTEDESSRSPEDLERGAAPVSAEAAAQGS- 303
Query: 325 SSHMEPVYMQQIGNAKISLSSSGVLLNGSLVPASTSP-VFLNGNSFIQGPSGVILNGLNV 383
+++ G +SS +L+NGS + AS SP V LNG GP VI+NGL +
Sbjct: 304 ------IFLAGTGPPAPCPASSSILVNGSFLAASGSPAVLLNG-----GP--VIINGLAL 350
Query: 384 GNTQAVALNP 393
G +A +L P
Sbjct: 351 G--EASSLGP 358
>gi|5174681 SIX homeobox 1 [Homo sapiens]
Length = 284
Score = 273 bits (697), Expect = 6e-73
Identities = 139/214 (64%), Positives = 158/214 (73%), Gaps = 9/214 (4%)
Query: 108 FSPDHVACVCEALQQGGNLDRLARFLWSLPQSDLLRGNESLLKARALVAFHQGIYPELYS 167
F+ + VACVCE LQQGGNL+RL RFLWSLP D L NES+LKA+A+VAFH+G + ELY
Sbjct: 9 FTQEQVACVCEVLQQGGNLERLGRFLWSLPACDHLHKNESVLKAKAVVAFHRGNFRELYK 68
Query: 168 ILESHSFESANHPLLQQLWYKARYTEAERARGRPLGAVDKYRLRRKFPLPRTIWDGEETV 227
ILESH F NHP LQQLW KA Y EAE+ RGRPLGAV KYR+RRKFPLPRTIWDGEET
Sbjct: 69 ILESHQFSPHNHPKLQQLWLKAHYVEAEKLRGRPLGAVGKYRVRRKFPLPRTIWDGEETS 128
Query: 228 YCFKEKSRNALKELYKQNRYPSPAEKRHLAKITGLSLTQVSNWFKNRRQRDRNPSETQSK 287
YCFKEKSR L+E Y N YPSP EKR LA+ TGL+ TQVSNWFKNRRQRDR +E + +
Sbjct: 129 YCFKEKSRGVLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDR-AAEAKER 187
Query: 288 SESDGNPSTEDESSKGHEDLSP----HPLSSSSD 317
++ N S SS LSP PL SSS+
Sbjct: 188 ENTENNNS----SSNKQNQLSPLEGGKPLMSSSE 217
>gi|219275578 SIX homeobox 2 [Homo sapiens]
Length = 291
Score = 261 bits (668), Expect = 1e-69
Identities = 133/223 (59%), Positives = 156/223 (69%), Gaps = 10/223 (4%)
Query: 108 FSPDHVACVCEALQQGGNLDRLARFLWSLPQSDLLRGNESLLKARALVAFHQGIYPELYS 167
F+ + VACVCE LQQGGN++RL RFLWSLP + L NES+LKA+A+VAFH+G + ELY
Sbjct: 9 FTQEQVACVCEVLQQGGNIERLGRFLWSLPACEHLHKNESVLKAKAVVAFHRGNFRELYK 68
Query: 168 ILESHSFESANHPLLQQLWYKARYTEAERARGRPLGAVDKYRLRRKFPLPRTIWDGEETV 227
ILESH F NH LQQLW KA Y EAE+ RGRPLGAV KYR+RRKFPLPR+IWDGEET
Sbjct: 69 ILESHQFSPHNHAKLQQLWLKAHYIEAEKLRGRPLGAVGKYRVRRKFPLPRSIWDGEETS 128
Query: 228 YCFKEKSRNALKELYKQNRYPSPAEKRHLAKITGLSLTQVSNWFKNRRQRDRNPSETQSK 287
YCFKEKSR+ L+E Y N YPSP EKR LA+ TGL+ TQVSNWFKNRRQRDR
Sbjct: 129 YCFKEKSRSVLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDR-------A 181
Query: 288 SESDGNPSTEDESSKGHEDLS---PHPLSSSSDGITNLSLSSH 327
+E+ + E+ +S H L+ L SS D T H
Sbjct: 182 AEAKERENNENSNSNSHNPLNGSGKSVLGSSEDEKTPSGTPDH 224
>gi|186910311 SIX homeobox 6 [Homo sapiens]
Length = 246
Score = 229 bits (583), Expect = 1e-59
Identities = 109/178 (61%), Positives = 137/178 (76%), Gaps = 4/178 (2%)
Query: 106 LAFSPDHVACVCEALQQGGNLDRLARFLWSLPQS----DLLRGNESLLKARALVAFHQGI 161
L FSP VA VCE L++ G+++RL RFLWSLP + + L NES+L+ARA+VAFH G
Sbjct: 7 LNFSPQQVAGVCETLEESGDVERLGRFLWSLPVAPAACEALNKNESVLRARAIVAFHGGN 66
Query: 162 YPELYSILESHSFESANHPLLQQLWYKARYTEAERARGRPLGAVDKYRLRRKFPLPRTIW 221
Y ELY ILE+H F +H LQ LW +A Y EAE+ RGRPLG VDKYR+R+KFPLPRTIW
Sbjct: 67 YRELYHILENHKFTKESHAKLQALWLEAHYQEAEKLRGRPLGPVDKYRVRKKFPLPRTIW 126
Query: 222 DGEETVYCFKEKSRNALKELYKQNRYPSPAEKRHLAKITGLSLTQVSNWFKNRRQRDR 279
DGE+ +CFKE++R+ L+E Y Q+ YP+P++KR LA+ TGL+ TQV NWFKNRRQRDR
Sbjct: 127 DGEQKTHCFKERTRHLLREWYLQDPYPNPSKKRELAQATGLTPTQVGNWFKNRRQRDR 184
>gi|4885597 sine oculis homeobox homolog 3 [Homo sapiens]
Length = 332
Score = 224 bits (570), Expect = 3e-58
Identities = 104/178 (58%), Positives = 138/178 (77%), Gaps = 4/178 (2%)
Query: 106 LAFSPDHVACVCEALQQGGNLDRLARFLWSLPQS----DLLRGNESLLKARALVAFHQGI 161
L FSP+ VA VCE L++ G+++RL RFLWSLP + + + +ES+L+ARA+VAFH G
Sbjct: 85 LNFSPEQVASVCETLEETGDIERLGRFLWSLPVAPGACEAINKHESILRARAVVAFHTGN 144
Query: 162 YPELYSILESHSFESANHPLLQQLWYKARYTEAERARGRPLGAVDKYRLRRKFPLPRTIW 221
+ +LY ILE+H F +H LQ +W +A Y EAE+ RGRPLG VDKYR+R+KFPLPRTIW
Sbjct: 145 FRDLYHILENHKFTKESHGKLQAMWLEAHYQEAEKLRGRPLGPVDKYRVRKKFPLPRTIW 204
Query: 222 DGEETVYCFKEKSRNALKELYKQNRYPSPAEKRHLAKITGLSLTQVSNWFKNRRQRDR 279
DGE+ +CFKE++R+ L+E Y Q+ YP+P++KR LA+ TGL+ TQV NWFKNRRQRDR
Sbjct: 205 DGEQKTHCFKERTRSLLREWYLQDPYPNPSKKRELAQATGLTPTQVGNWFKNRRQRDR 262
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 57.0 bits (136), Expect = 7e-08
Identities = 99/463 (21%), Positives = 176/463 (38%), Gaps = 59/463 (12%)
Query: 280 NPSETQSKSESDGNPSTEDESSKGHEDLSPHPLSSSSDGITNL-SLSSHMEPVYMQQIGN 338
N S T S++ STE SS +++ P S+ S+G T L S+S PV +
Sbjct: 471 NLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEAS- 529
Query: 339 AKISLSSSGVLLNGSLVPASTSPVFLNGNSFIQGPSGVILNGLNVGNTQAVALNPPKMSS 398
+LS++ V + P +TS +S P G + N P +
Sbjct: 530 ---TLSTTPV---DTSTPVTTSS---EASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTR 580
Query: 399 NIVSNGISMTDILGSTSQDVKEFKVLQSSANSATTTSYSPSVPVSFPG---------LIP 449
+VS+ S T +T D F S A+S++TT+ S+P S +
Sbjct: 581 LVVSSEASTT---STTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVS 637
Query: 450 STEVKREGIQTVASQDGGSVVTFTTPVQINQYGIVQIPNSGANSQFLNGSIGFSPLQLPP 509
+T V T+++ S TT + S S + GS + + +
Sbjct: 638 TTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNT 697
Query: 510 VSVAASQGN------------------ISVSSSTSDGSTFTSES--------TTVQQGKV 543
VA+S+ + S S +T+DG++ + + T++ K
Sbjct: 698 TLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKT 757
Query: 544 FLSSLAPSAVVYTVPNTGQTIGSVKQEGLERSLVFSQLMPVNQNAQVNANLSSENISGSG 603
L+S S + T +T I + + + MP++ ++ + L+S +S +
Sbjct: 758 LLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITP 817
Query: 604 LHPLASSLVNVSPTHNFSLSPSTLLNPTELNRDIADSQPMSAPVASKS------TVTSVS 657
+ +S ++ +P S S + TE++ ++ S P ++ S T VS
Sbjct: 818 VTSPEASTLSTTPVD----SNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVS 873
Query: 658 NTNYATLQNCSLITGQDLLSVPMTQAALGEIVPTAEDQVGHPS 700
T AT +L T S P+T + PT + P+
Sbjct: 874 TTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPT 916
Score = 52.4 bits (124), Expect = 2e-06
Identities = 102/445 (22%), Positives = 171/445 (38%), Gaps = 40/445 (8%)
Query: 280 NPSETQSKSESDGNPSTEDESSKGHEDLSPHPLSSSSDGITNLSLSSHMEPVYMQQIGNA 339
N +E S + ++G+ T S+G L+ PLS++ S S PV
Sbjct: 2077 NSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLS-TTPVDSNSPVIT 2135
Query: 340 KISLSSSGVLLNGSLVPAST-----SPVFLNGNSFIQGPSGVI--LNGLNVGNTQAVALN 392
+SSS + G+ + ST +P+ S S I L+ V + V +
Sbjct: 2136 STEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNS 2195
Query: 393 PPKMSSNIVSNGISM---TDILGS---TSQDVKEFKVLQSSANSATTTSYSPSVPVSFPG 446
SS S G SM T GS TS V V+ S A++ + T S PV+
Sbjct: 2196 TEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTST 2255
Query: 447 LIPSTEVKREG--IQTVASQDGGSVVTFT----TPVQINQYGIVQIPNSGANSQFLNGSI 500
S+ EG I T +G + +T T V ++ + +N+ F +
Sbjct: 2256 EATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTE 2315
Query: 501 GFSPLQLPPVSVAASQGNISVSSSTSDGSTFTSESTTVQQGKVFLSSLAPSAVVYTVPNT 560
SP PP ++G +S++S+G+T T + ++S S + T +T
Sbjct: 2316 ASSP---PP----TAEGTSMPTSTSSEGNT---PLTRMPVSTTMVASFETSTLSTTPADT 2365
Query: 561 GQTIGSVKQEGLERSLVFSQLMPVNQNAQVNANLSSENISGSGLHPLASSLVNVSPTHNF 620
+ + Q G + MP + ++ + L+S +S P+ SS + T
Sbjct: 2366 STPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVS---TMPVVSSEASTHSTTPV 2422
Query: 621 SLSPSTLLNPTELNRDIADSQPMSAPVASKSTVTS------VSNTNYATLQNCSLITGQD 674
S + + TE + ++ S P + S T+ VS T + + +L T
Sbjct: 2423 DTS-TPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPV 2481
Query: 675 LLSVPMTQAALGEIVPTAEDQVGHP 699
S PMT + PT + + P
Sbjct: 2482 DTSTPMTTSTEASSSPTTAEDIVVP 2506
Score = 47.8 bits (112), Expect = 4e-05
Identities = 92/451 (20%), Positives = 165/451 (36%), Gaps = 55/451 (12%)
Query: 284 TQSKSESDGNPSTEDESSKGHEDLSPHPLSSSS--------------DGITNLSLSSHME 329
+ S + +DG S+G L+ P+S+ D T ++ S+
Sbjct: 1552 SSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEAS 1611
Query: 330 PVYMQQIGNAKISLSSSGVLLNGSLVPASTSPVFLNGNSFIQGPSGVILNGLNVGNTQAV 389
+ + IS S G L S +P ST+PV P L+ V + V
Sbjct: 1612 SSTTAEGSSMTISTPSEGSPLLTS-IPVSTTPV--------ASPEASTLSTTPVDSNSPV 1662
Query: 390 ALNPPKMSSNIVSNGISMTDILGS------TSQDVKEFKVLQSSANSATTTSYSPSVPVS 443
+ SS + G SM + TS V+ V S+ ++ +TT S PV+
Sbjct: 1663 ITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVT 1722
Query: 444 FPGLIPSTEVKREGIQTVASQDGGSVVTFTTPVQINQYGIVQIPNSGANSQFLNGSIGFS 503
S+ EG S + TTP+ + +S A++ S
Sbjct: 1723 TSTEARSSPTTSEG----TSMPNSTPSEGTTPLTSIPVSTTPVLSSEAST--------LS 1770
Query: 504 PLQLPPVSVAASQGNISVSSSTSDGSTFTSESTTVQQGKVFLSS--LAPSAVVYTVPNTG 561
+ + + + S +T++G++ + +T+ +G L+S ++ + V + +T
Sbjct: 1771 ATPIDTSTPVTTSTEATSSPTTAEGTSIPT--STLSEGMTPLTSTPVSHTLVANSEASTL 1828
Query: 562 QTIGSVKQEGLERSLVFSQLMPVNQNAQVNANLSSENISGSGLHPLASSLVNVSPTHNFS 621
T + S S + + + SE + P++++ V S T+ S
Sbjct: 1829 STTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLS 1888
Query: 622 LSPSTLLNPTELNRDIADS--------QPMSAPVASKSTVTS--VSNTNYATLQNCSLIT 671
+P+ P ++ S P S P + +TS VS T A+ + +L T
Sbjct: 1889 TTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLST 1948
Query: 672 GQDLLSVPMTQAALGEIVPTAEDQVGHPSPA 702
P+T + PT D P+PA
Sbjct: 1949 TLADTRTPVTTYSQASSSPTTADGTSMPTPA 1979
Score = 47.4 bits (111), Expect = 5e-05
Identities = 88/426 (20%), Positives = 157/426 (36%), Gaps = 50/426 (11%)
Query: 282 SETQSKSESDGNPSTEDESSKGHEDLSPHPLSSSSDGITNLSLSSHMEPVYMQQIGNAKI 341
S T S S STE SS + + P S+ S+G T P+ + +
Sbjct: 2536 STTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGST---------PLRSMPVSTKPL 2586
Query: 342 SLSSSGVLLNGSLVPASTSPVFLNGNSFIQGPSGVILNGLNVGNTQAVALNPPKMSSNIV 401
+ S + L S P TS P+ + + V+ + + + +
Sbjct: 2587 ASSEASTL---STTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTM 2643
Query: 402 SNGISMTDILGSTSQDVKEFKVLQSSANSATTTSYSPSVPVSFPGLIPSTEVKREGIQTV 461
S L +T D + + +S+ TT+ S+P S PG ST + + T
Sbjct: 2644 PVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPG-ERSTPLTNILVSTT 2702
Query: 462 ASQDGGSVVTFTTPVQINQYGIVQIPNSGANSQFLNGSIGFSPLQLPPVSVAASQGNISV 521
+ + TTPV + + S S S ++G
Sbjct: 2703 LLANSEASTLSTTPVDTS----TPVTTSAEASS----------------SPTTAEGTSMR 2742
Query: 522 SSSTSDGSTFTSE--STTVQQGKVFLSSLAPSAVVYTVPNTGQTIGSVKQEGLERSLVFS 579
S+ SDGST + +T+ S+++ +AV ++P T T S E +
Sbjct: 2743 ISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVT---- 2798
Query: 580 QLMPVNQNAQVNANLSSENISGSGLHPLASSLVNVSPTHNFSLSPSTLLNPTELNRDIAD 639
MP + ++ + L+S ++ + P+ASS T S + + T+ +
Sbjct: 2799 -SMPTSTPSETSTPLTSMPVNHT---PVASSEAGTLSTTPVDTS-TPVTTSTKASSSPTT 2853
Query: 640 SQPMSAPVASKS------TVTSVSNTNYATLQNCSLITGQDLLSVPMTQAALGEIVPTAE 693
++ + P+++ S T VS T A+ + +L T S+P+T + G PT
Sbjct: 2854 AEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTA 2913
Query: 694 DQVGHP 699
+ P
Sbjct: 2914 EGTSMP 2919
Score = 47.0 bits (110), Expect = 7e-05
Identities = 91/417 (21%), Positives = 159/417 (38%), Gaps = 52/417 (12%)
Query: 288 SESDGNPSTEDESSKGHEDLSPHPLSSSSDGITNLSLSSHMEPVYMQQIGNAKISLSSSG 347
SE+ +P+T +++S ++ S S +T++ +S+ PV + N + S
Sbjct: 428 SEASSSPTTAEDTS-----IATSTPSEGSTPLTSMPVST--TPVASSEASNLSTTPVDSK 480
Query: 348 VLLNGSLVPASTSPVFLNGNSFIQGPSGVILNGLNVGNTQAVALNPPKMSSNIVSNGISM 407
+ S AS+SP NS P+ G + +V+ P S
Sbjct: 481 TQVTTS-TEASSSPPTAEVNSM---PTSTPSEGSTPLTSMSVSTMPVASSE--------- 527
Query: 408 TDILGSTSQDVKEFKVLQSSANSATTTSYSPSVPVSFP--GLIPSTEVKREGIQTVASQD 465
L +T D S A+S++TT S+P S P G P T + V+S+
Sbjct: 528 ASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSE- 586
Query: 466 GGSVVTFTTPVQINQYGIVQIPNSGANSQFLNGSIGFSPLQLPPVSVAASQGNISVSSST 525
+ T TTP N + S +++ S+ P S + +G S S
Sbjct: 587 --ASTTSTTPADSNTFVTTSSEASSSSTTAEGTSM--------PTSTYSERGTTITSMSV 636
Query: 526 SDGSTFTSESTTVQQGKVFLSSLAPSAVVYTVPNTGQTIGSVKQEGLERSLVFSQLMPVN 585
S +SE++T LS+ + +T T S EG MP +
Sbjct: 637 STTLVASSEAST-------LSTTPVDSNTPVTTSTEATSSSTTAEGTS--------MPTS 681
Query: 586 QNAQVNANLSSENISGSGLHPLASSLVNVSPTHNFS-LSPSTLLNPTELNRDIADSQPMS 644
+ + L+S ++ + + +S ++ +P + ++ ST + + D A S P S
Sbjct: 682 TYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGA-SMPTS 740
Query: 645 APVASKSTVTS--VSNTNYATLQNCSLITGQDLLSVPMTQAALGEIVPTAEDQVGHP 699
P + +TS VS T + + +L T S +T + PT + P
Sbjct: 741 TPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMP 797
Score = 45.8 bits (107), Expect = 2e-04
Identities = 106/468 (22%), Positives = 172/468 (36%), Gaps = 60/468 (12%)
Query: 281 PSETQSKSESDGNPSTEDESSKGHEDLSPHPLSSSSDGITNLSLSSHMEPVYMQQIGNAK 340
PSET + S T SS+ LS P+ +S+ T+ SS P + I
Sbjct: 2805 PSETSTPLTSMPVNHTPVASSEAGT-LSTTPVDTSTPVTTSTKASS--SPTTAEGIV-VP 2860
Query: 341 ISLSSSGVLLNGSLVPASTSPVFLNGNSFIQG-------PSGVILNGLN----VGNTQAV 389
IS +S G L S +P ST+PV + S + P G + T
Sbjct: 2861 ISTASEGSTLLTS-IPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMP 2919
Query: 390 ALNPPKMSSNIVSNGISMTDILGS-------TSQDVKEFKVLQSSANSATTTSYSPSVPV 442
P ++S+ + S +S + GS T D + + A+S+ TT+ S+P+
Sbjct: 2920 ISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPI 2979
Query: 443 SFPG--LIPSTEVKREGIQTVASQ---------DGGSVVTFTT-----PVQINQYGIVQI 486
S PG P T + + +S+ D + VT +T P GI
Sbjct: 2980 STPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPIS 3039
Query: 487 PNSGANSQFLNGSIGFSPLQLPPVSVAAS---QGNISVSSSTSDGSTFTSESTTVQQGKV 543
S ++ + + +P+ +P S ++ N V +ST S+ T T
Sbjct: 3040 TPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPIST 3099
Query: 544 FLSSLAP--SAVVYTVPNTGQTIGSVKQEGLERSLVFSQLMPVNQNAQVNANLS------ 595
+ P V T P T I ++ ++ S + + + + S
Sbjct: 3100 YSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTP 3159
Query: 596 SENISGSGLHPLASSLVNVSPTHNFSLSPSTLLNPTELNRDIADSQ-------PMSAPVA 648
SE + P+++ LV S S +P P + + S P S P
Sbjct: 3160 SEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSE 3219
Query: 649 SKSTVTS--VSNTNYATLQNCSLITGQDLLSVPMTQAA-LGEIVPTAE 693
+ +TS VSNT A+ + L T + P+T + PTAE
Sbjct: 3220 GMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAE 3267
Score = 45.4 bits (106), Expect = 2e-04
Identities = 90/428 (21%), Positives = 163/428 (38%), Gaps = 42/428 (9%)
Query: 281 PSETQSKSESDGNPSTEDESSKGHEDLSPHPLSSSSDGITNLSLSSHMEPVYMQQIGNAK 340
PSE ++ +S +T +S+ LS P+ S+S +T+ ++SS P I +
Sbjct: 1450 PSEGKTPLKSIPVSNTPVANSEA-STLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAIST 1508
Query: 341 ISLSSSGVLLNGSLVPASTSPVF---LNGNSFIQGPSGVILNGLNVGNTQAVALNPPKMS 397
S S+ + + +P ST+ V +N S + + + ++ + M
Sbjct: 1509 PSEGSTAL----TSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQ 1564
Query: 398 SNIVSNGISMTDILGSTSQDVKEFKVLQSSANSATTTSYSPSVPVSFPGLIPSTEVKREG 457
++ S G + TS V V+ S AN+ +TT V+ S+
Sbjct: 1565 TSTYSEGSTPL-----TSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGS 1619
Query: 458 IQTVASQDGGSVVTFTTPVQINQYGIVQIPNSGANSQFLNGSIGFSPLQLPPV-SVAASQ 516
T+++ GS + + PV V P + S L PV S +
Sbjct: 1620 SMTISTPSEGSPLLTSIPVSTTP---VASPEA-------------STLSTTPVDSNSPVI 1663
Query: 517 GNISVSSSTSDGSTFTSESTTVQQGKVFLSSLAPSAVVYTVPNTGQTIGSVKQEGLERSL 576
+ VSSS + + ++T +G+ L+S+ V T P I ++ ++ S
Sbjct: 1664 TSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSI----TVRTTPVASSAISTLSTTPVDNST 1719
Query: 577 VFSQLMPVNQNAQVNANLSSENISGS-GLHPLASSLVNVSPTHNFSLSPSTLLNPTELNR 635
+ + + S N + S G PL S V+ +P + S ++ L+ T ++
Sbjct: 1720 PVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLS---SEASTLSATPID- 1775
Query: 636 DIADSQPMSAPVASKSTVTSVSNTNYATLQNCSLITGQDLLSVPMTQAALGEIVPTAEDQ 695
S P++ + S+ T+ T+ T +T V T A E +
Sbjct: 1776 ---TSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTP 1832
Query: 696 VGHPSPAV 703
V SP V
Sbjct: 1833 VDSNSPVV 1840
Score = 44.7 bits (104), Expect = 3e-04
Identities = 106/488 (21%), Positives = 189/488 (38%), Gaps = 65/488 (13%)
Query: 282 SETQSKSESDGNPST------EDESSKGHEDLSPHPLSSSSDGITNLSLSSHMEPVYMQQ 335
SET + S + + ST + SS D + P S+ S+G T L+ PV +
Sbjct: 1057 SETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLT----SVPVSTRL 1112
Query: 336 IGNAKISLSSSGVLLNGSLVPAST----SPVFLNGNSFIQGPSGVILNGLNVGNTQAVAL 391
+ +++ S S+ + V ST SP G S P + G T ++
Sbjct: 1113 VVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPP-------SEGTTPLASM 1165
Query: 392 NPPKMSSNIVSNGISMTDILGSTSQDVKEFKVLQSSANSATTTSYSPSVPVSFPGLIPST 451
P ++ +VS S + L +T D K + A+S T+ S+P S PG ST
Sbjct: 1166 --PVSTTLVVS---SEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPG-ERST 1219
Query: 452 EVKREGIQTVASQDGGSVVTFTTPVQINQYGIVQIPNSGANSQFLNGSIGFSPLQLPPVS 511
+ ++ + T+PV + + S S S
Sbjct: 1220 PLTSMPVRHTPVASSEASTLSTSPVDTS----TPVTTSAETSS----------------S 1259
Query: 512 VAASQGNISVSSSTSDGSTFTSESTTVQQGKVFLSSLAPSAVVYTVPNTGQTIGSVKQEG 571
++G +S+TS+GST T++ ++S S ++ T +T + + +
Sbjct: 1260 PTTAEGTSLPTSTTSEGSTLL---TSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVS 1316
Query: 572 LERSLVFSQLMPVNQNAQVNANLSSENISGSGLHPLASSLVNVSPTHN---FSLSPSTLL 628
+ MP + ++ L+S ++ + + A S+++ +P N + S
Sbjct: 1317 SSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACS 1376
Query: 629 NPTELNRDIADSQPMSAPVASKSTVTS--VSNTNYATLQNCSLITGQDLLSVPMTQAALG 686
+PT S P S P + +TS VS T + + +L S P T +A
Sbjct: 1377 SPTTSE---GTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEA 1433
Query: 687 EIVPTAEDQVGHPSPAVHQDFVQEHRLVLQSVANMKENFLSNSESKATSSLMMLDSKSKY 746
PT + + P+ E + L+S+ + ++NSE+ +T S +DS S
Sbjct: 1434 TSSPTTAEGISIPTST-----PSEGKTPLKSIP-VSNTPVANSEA-STLSTTPVDSNSPV 1486
Query: 747 VLDGMVDT 754
V V +
Sbjct: 1487 VTSTAVSS 1494
Score = 44.7 bits (104), Expect = 3e-04
Identities = 102/463 (22%), Positives = 167/463 (36%), Gaps = 68/463 (14%)
Query: 279 RNPSETQSKSES-----DGNPSTEDESSKGHEDLSPHPLSSSSDGITNLSLSSHMEPVYM 333
R P T S++ S DG S+G L+ PLS T L +SS +
Sbjct: 1954 RTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLS------TTLVVSSEASTLST 2007
Query: 334 QQIGNAKISLSSSGVLLNGSLVPASTSPVFLNGNSF-IQGPSG--VILNGLNVGNTQAVA 390
+ + + +S+ S+SP G S PS L G+ V T V+
Sbjct: 2008 TPVDTSTPATTST---------EGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVS 2058
Query: 391 LNPPKMSSNIVSNGISMTDILGSTSQDVKEFKVLQSSANSATTTSYSPSVPVSFPGLIPS 450
+S+ V + +T+ ++S E + SA S + + S+P+S P
Sbjct: 2059 SEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLT-SIPLS---TTPV 2114
Query: 451 TEVKREGIQTVASQDGGSVVTFTTPVQINQYGIVQIPNSGANSQFLNGSIGFSPLQLPPV 510
+ + T V+T T + IP G + Q S +PL PV
Sbjct: 2115 ASPEASTLSTTPVDSNSPVITST------EVSSSPIPTEGTSMQTSTYSDRRTPLTSMPV 2168
Query: 511 S--VAASQGNISVSSSTSDGSTFTSEST-----------------TVQQGKVFLSSLAPS 551
S V AS ++S++ D ST + ST T +G +S+ P
Sbjct: 2169 STTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSM-PV 2227
Query: 552 AVVYTVPNTGQTIGSVKQEG---LERSLVFSQLMPVNQNAQVNANLSSENISGSGLHPLA 608
+ + V + T+ + + + S + + + + SE + P++
Sbjct: 2228 STMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVS 2287
Query: 609 SSLVNVSPTHNFSLSPSTLLNPTELNRDIADSQPMSAPVASKSTVTS-----------VS 657
+LV S S +P P + + A S P +A S T TS VS
Sbjct: 2288 HTLVANSEVSTLSTTPVDSNTPFTTSTE-ASSPPPTAEGTSMPTSTSSEGNTPLTRMPVS 2346
Query: 658 NTNYATLQNCSLITGQDLLSVPMTQAALGEIVPTAEDQVGHPS 700
T A+ + +L T S P+T + PT D P+
Sbjct: 2347 TTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPT 2389
Score = 42.0 bits (97), Expect = 0.002
Identities = 109/504 (21%), Positives = 183/504 (36%), Gaps = 98/504 (19%)
Query: 282 SETQSKSESDGNPSTEDESSKGHEDLSPHPLSSSSDGITNLSLSSHMEPVYMQQIGNAKI 341
S T + + STE SS + + P S+ S+G T L+ PV + N+++
Sbjct: 2241 SATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSI----PVSHTLVANSEV 2296
Query: 342 S-LSSSGVLLNGSLVP---ASTSPVFLNGNSFIQGPSG---VILNGLNVGNTQAVALNPP 394
S LS++ V N AS+ P G S S L + V T +
Sbjct: 2297 STLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETS 2356
Query: 395 KMSSNIVSNGISMTDI--LGS----------------------TSQDVKEFKVLQSSANS 430
+S+ +T GS TS V V+ S A++
Sbjct: 2357 TLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEAST 2416
Query: 431 ATTTSYSPSVPVSFPGLIPSTEVKREG--IQTVASQDG----GSVVTFTTPVQINQYG-- 482
+TT S PV+ S+ EG I T +G S+ TTPV ++ G
Sbjct: 2417 HSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTL 2476
Query: 483 ---------------------------IVQIPNSGANSQFLNG-SIGFSPLQLPPVSV-- 512
+V I + S L + +P+ P S
Sbjct: 2477 STTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLS 2536
Query: 513 ---------AASQGNISVSSSTSDG-----STFTSESTTVQQGKVFLSSLAPS--AVVYT 556
+ IS S+++++G ST++ ST ++ V LA S + + T
Sbjct: 2537 TTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLST 2596
Query: 557 VP-NTGQTIGSVKQEGLERSLVFSQLMPVNQNAQVNANLSSENISGSGLHPLASSLVNVS 615
P +T + + + + MP++ ++V+ +L+S +S + +S ++ +
Sbjct: 2597 TPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTT 2656
Query: 616 PTHNFSL---SPSTLLNPTELNRDIADSQPMSAPVASKSTVTS--VSNTNYATLQNCSLI 670
P +L S T +PT S P S P + +T+ VS T A + +L
Sbjct: 2657 PVDTRTLVTTSTGTSSSPTTAE---GSSMPTSTPGERSTPLTNILVSTTLLANSEASTLS 2713
Query: 671 TGQDLLSVPMTQAALGEIVPTAED 694
T S P+T +A PT +
Sbjct: 2714 TTPVDTSTPVTTSAEASSSPTTAE 2737
Score = 40.8 bits (94), Expect = 0.005
Identities = 77/344 (22%), Positives = 126/344 (36%), Gaps = 40/344 (11%)
Query: 354 LVPASTSPVFLNGNSFIQGPSGVILNGLNVGNTQAVALNPPKMSSNIVSNGISMTDILGS 413
L P + + L+ N + G I G +V N Q L S V G + G+
Sbjct: 19 LPPQAAAEQDLSVNRAVWDGGGCISQG-DVLNRQCQQL------SQHVRTGSAANTATGT 71
Query: 414 TSQDVKEFKVLQSSANSATTTSYSPSVPVSFPGLIPSTEVKREGIQTVASQDGGSVVTFT 473
TS +V E ++ S + + TS SV PG + ST + +T + S F
Sbjct: 72 TSTNVVEPRMYLSCSTNPEMTSIESSVTSDTPG-VSSTRMTPTESRTTSESTSDSTTLFP 130
Query: 474 TPVQINQYGI----VQIPNSGANSQFLNGSIGF-SPLQLPPVSVAASQGNISVSSSTSDG 528
+ + +P S + + ++ ++ F S LP S S+
Sbjct: 131 SSTEDTSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTT 190
Query: 529 STFTSESTTVQQGKVFLSSLAPSAVVYTVPNTGQTIGSVKQEGLERSLVFSQLMPVNQNA 588
ST S S T + S + P T ++K E + + + ++
Sbjct: 191 STQASSSPTTPESTTIPKSTNSEG---STPLTSMPASTMKVASSEAITLLTTPVEISTPV 247
Query: 589 QVNANLSSENISGSGLHPLASSLVNVSPTHNFSLSPSTLLNPTELNRDIADSQPMSAPVA 648
++A SS + G SL N +P+ T L R P+S +
Sbjct: 248 TISAQASSSPTTAEG-----PSLSNSAPSG----------GSTPLTR-----MPLSVMLV 287
Query: 649 SKSTVTSVSNTNYATLQNCSLITGQDLLSVPMTQAALGEIVPTA 692
S +++S T AT N +IT + S P T A G +PT+
Sbjct: 288 VSSEASTLSTTPAAT--NIPVITSTEASSSPTT--AEGTSIPTS 327
Score = 40.0 bits (92), Expect = 0.008
Identities = 100/418 (23%), Positives = 161/418 (38%), Gaps = 55/418 (13%)
Query: 295 STEDESSKGHEDLSPHPLSSSSDGITNLSLSSHMEPVYMQQIGNAKISLSSSGVLLNGSL 354
STE S + + P+S+ S+G L+ PV + + + + S S+ + + S
Sbjct: 781 STEASCSPTTTEGTSMPISTPSEGSPLLTSI----PVSITPVTSPEASTLSTTPVDSNSP 836
Query: 355 VPAST----SPVFLNGNSFIQGPSGVILNGLNVGNTQAVALNPPKMSSNIVSNGISMTDI 410
V ST SP G S P+ G L +S+ +V+ T
Sbjct: 837 VTTSTEVSSSPTPAEGTSM---PTSTYSEG-------RTPLTSMPVSTTLVATSAIST-- 884
Query: 411 LGSTSQDVKEFKVLQSSANSATTTSYSPSVPVSFP--GLIPSTEVKREGIQTVASQD--- 465
L +T D + A S+ TTS S+P S P G P T + V+S+
Sbjct: 885 LSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTL 944
Query: 466 GGSVVTFTTPVQINQYGIVQIPNS-GANSQFLNGSIGFSPLQLPPVSVAASQGNISVSSS 524
+ V +TPV + + G + S G +PL PVS + +S
Sbjct: 945 SATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVS-----HTLVANSE 999
Query: 525 TSDGSTFTSESTTVQQGKVFLSSLAPSAVVYTVPNTGQTIGSVKQEGLERSLVFSQLMPV 584
S ST +S T SS P+A ++P + + GS L R MPV
Sbjct: 1000 ASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTP---LTR-------MPV 1049
Query: 585 NQNAQVNANLSSENISGSGLHPLASSLVNVSPTHNFSLSPSTLLNPTELNRDI--ADSQP 642
+ ++ S+ L + T++ + S ST + T + S P
Sbjct: 1050 STTMVASSETST-------LSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTP 1102
Query: 643 M-SAPVASKSTVTSVSNTNYATLQNCSL--ITGQDLLSVPMTQAALGEIVPTAEDQVG 697
+ S PV+++ V+S ++T T + S+ T + S P T A G +PT+ G
Sbjct: 1103 LTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTT--AEGTSIPTSPPSEG 1158
Score = 39.7 bits (91), Expect = 0.011
Identities = 103/470 (21%), Positives = 170/470 (36%), Gaps = 107/470 (22%)
Query: 282 SETQSKSESDGNPSTEDESSKGHEDLSPHPLSSSSDGITNL-SLSSHMEPVYMQQIGNAK 340
S T + + STE SS + + P S+ S+G T L S+ PV +
Sbjct: 1711 STTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLS 1770
Query: 341 ISLSSSGVLLNGSLVPASTSPVFLNGNSFIQGPSGVILNGLN-----------VGNTQAV 389
+ + + S A++SP G S P+ + G+ V N++A
Sbjct: 1771 ATPIDTSTPVTTS-TEATSSPTTAEGTSI---PTSTLSEGMTPLTSTPVSHTLVANSEAS 1826
Query: 390 ALNPPKMSSN---IVSNGISM-------TDILGSTSQD---------VKEFKVLQSSANS 430
L+ + SN + S +S T I ST + V V S N+
Sbjct: 1827 TLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNT 1886
Query: 431 ATTTSYSPSVPVSFPGLIPS-----------TEVKREG----------IQTVASQDGGSV 469
+TT S PV+ + S T REG TVAS + +
Sbjct: 1887 LSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSE---I 1943
Query: 470 VTFTTPVQINQYGIVQIPNSGANSQFLNG--------SIGFSPLQLPPVSV-------AA 514
T +T + + + + ++ +G S G +PL P+S A+
Sbjct: 1944 NTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEAS 2003
Query: 515 SQGNISVSSSTSDGSTFTSESTTVQQGKVFLSSLAPSAVVYTVPNTGQTIGS---VKQEG 571
+ V +ST ++ S+ G + + PS T P G + + V EG
Sbjct: 2004 TLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSE--RTTPLAGMPVSTTLVVSSEG 2061
Query: 572 LERSLVFSQLMPVNQNAQV-NANLSSENISGSGLHPLASSLVNVSPTHNFSLSPSTLLNP 630
S PV+ QV N+ +S + + G SS+ +P+ L S L+
Sbjct: 2062 NTLSTT-----PVDSKTQVTNSTEASSSATAEG-----SSMTISAPSEGSPLLTSIPLST 2111
Query: 631 TELNRDIADSQPMSAPVASKSTVTSVSNTNYATLQNCSLITGQDLLSVPM 680
T P+++P AS + T V + N +IT ++ S P+
Sbjct: 2112 T----------PVASPEASTLSTTPVDS-------NSPVITSTEVSSSPI 2144
Score = 38.9 bits (89), Expect = 0.019
Identities = 104/508 (20%), Positives = 191/508 (37%), Gaps = 71/508 (13%)
Query: 282 SETQSKSESDGNP----STEDESSKGHEDLSPHPLSSSSDGITNLSL------------- 324
S T S+S SD STED SS + + P+S+ S+ + ++
Sbjct: 115 SRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPLPSFEA 174
Query: 325 -SSHMEPVYMQQIGNAKISLSSSGVLLNGSLVPAST-----SPVFLNGNSFIQGPSGVIL 378
+S V M SSS + +P ST +P+ S ++ S +
Sbjct: 175 YTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAI 234
Query: 379 NGLN--VGNTQAVALNPPKMSSNIVSNGISMTDILGS------TSQDVKEFKVLQSSANS 430
L V + V ++ SS + G S+++ S T + V+ S A++
Sbjct: 235 TLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEAST 294
Query: 431 ATTTSYSPSVPVSFPGLIPSTEVKREG--IQTVASQDGGSVVT----FTTPVQINQYGIV 484
+TT + ++PV S+ EG I T +G + +T T PV ++ +
Sbjct: 295 LSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTL 354
Query: 485 QIPNSGANSQFLNGSIGFSPLQLPPVSVAASQGNISVSSSTSDGSTFTSESTTVQQGKVF 544
I ++ + P LP + A S ++S+ S+GST T
Sbjct: 355 SITPVDTSTLVTTST---EPSSLPTTAEATSM----LTSTLSEGST----PLTNMPVSTI 403
Query: 545 LSSLAPSAVVYTVPNTGQTIGSVKQEGLERSLVFSQLMPVNQNAQVNANLSSENISGSGL 604
L + + ++ T+P +T + E S ++ + + SE +
Sbjct: 404 LVASSEASTTSTIPVDSKTFVTTASEA-------SSSPTTAEDTSIATSTPSEGSTPLTS 456
Query: 605 HPLASSLVNVSPTHNFSLSP----STLLNPTELNRDIADSQPMSAPVASKS------TVT 654
P++++ V S N S +P + + TE + ++ S P ++ S T
Sbjct: 457 MPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSM 516
Query: 655 SVSNTNYATLQNCSLITGQDLLSVPMTQAALGEIVPTAEDQVGHPSPAVHQ------DFV 708
SVS A+ + +L T S P+T ++ T + P+ + +
Sbjct: 517 SVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMP 576
Query: 709 QEHRLVLQSVANMKENFLSNSESKATSS 736
RLV+ S A+ ++S + T+S
Sbjct: 577 VSTRLVVSSEASTTSTTPADSNTFVTTS 604
Score = 38.9 bits (89), Expect = 0.019
Identities = 86/391 (21%), Positives = 142/391 (36%), Gaps = 36/391 (9%)
Query: 282 SETQSKSESDGNPSTEDESSKGHEDLSPHPLSSSSDGITNLSLSSHMEPVYMQQIGNAKI 341
S T S + STE SS + + P S++S+G T LS+ + +
Sbjct: 3420 STTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSI---------MPLSTTPV 3470
Query: 342 SLSSSGVLLNGSLVPASTSPVFLNGNSFIQGPSGVILNGL---NVGNTQAVALNPPKMSS 398
+ S + L S P TS + P+ + + G N P ++
Sbjct: 3471 ASSEASTL---STTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTT 3527
Query: 399 NIVSNGISMTDILGSTSQDVKEFKVLQSSANSATTTSYSPSVPVSFPG---------LIP 449
+ S S L +T D F S A+S+ T ++ +S P L+
Sbjct: 3528 PVAS---SEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLS 3584
Query: 450 STEVKREGIQTVASQDGGSVVTFTTPVQINQYGIVQIPNSGANSQFLNGSIGFSPLQLPP 509
ST V T ++ TT Q N P S +PL + P
Sbjct: 3585 STYVTSSEASTPSTPSVDRSTPVTTSTQSNS---TPTPPEVITLPMSTPSEVSTPLTIMP 3641
Query: 510 VSVAASQGNISVSSSTSDGSTFTSESTTVQQGKVFLSSLAPSAVVYTVPNTGQTIGSVKQ 569
VS + + + ++ST T T T+ Q ++ + ++T P+ G T +
Sbjct: 3642 VSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWT-PSEGSTPLTTMP 3700
Query: 570 EGLER--SLVFSQLMPVNQNAQVNANLSSENISGSGLHPLASSLVNVS-PTHNFSLSPST 626
R S S L + S+E IS S L S+ ++VS P +L +
Sbjct: 3701 VSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSA--TLDSTTMSVSMPMEISTLGTTI 3758
Query: 627 LLNPTELNRDIADSQPMSAPVASKSTVTSVS 657
L++ T + R S P V + ++T+ S
Sbjct: 3759 LVSTTPVTRFPESSTPSIPSVYTSMSMTTAS 3789
Score = 37.4 bits (85), Expect = 0.054
Identities = 73/384 (19%), Positives = 142/384 (36%), Gaps = 65/384 (16%)
Query: 281 PSETQSKSESDGNPSTEDESSKGHEDLSPHPLSSSSDGITNLSLSSHMEPVYMQQIGNAK 340
PS + ST+ S+ ++ P+S+ S+ T P+ + +
Sbjct: 3596 PSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVST---------PLTIMPVSTTS 3646
Query: 341 ISLSSSGVLLNGSLVPASTSPVFLNGNSFIQGPSGVILNGLNVGNTQAVALNPPKMSSNI 400
+++S +G S +P TS + P + T P + S+ +
Sbjct: 3647 VTISEAGT---ASTLPVDTSTPVITSTQVSSSP-------VTPEGTTMPIWTPSEGSTPL 3696
Query: 401 VSNGISMTDILGSTSQDVKEFKVLQSSANSATTTSYSPSVPVSFPGLIPSTEVKREGIQT 460
+ +S T +V S ++ +T S S PV+ E I +
Sbjct: 3697 TTMPVSTT-------------RVTSSEGSTLSTPSVVTSTPVT---------TSTEAISS 3734
Query: 461 VASQDGGSVVTFTTPVQINQYGIVQIPNSGANSQFLNGSIGFSPLQLPPVSVA-ASQGNI 519
A+ D + ++ + P++I+ G + ++ ++F S P +S+ AS+G
Sbjct: 3735 SATLDS-TTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEG-- 3791
Query: 520 SVSSSTSDGSTFTSESTTVQQGKVFLSSLAPSAVVYTVPNTGQTIGSVKQEGLERSLVFS 579
S S +T +G+T STT ++ + L+++ S + P+ T+ + +
Sbjct: 3792 SSSPTTLEGTTTMPMSTTSERSTL-LTTVLISPISVMSPSEASTLSTPPGD--------- 3841
Query: 580 QLMPVNQNAQVNANLSSENISGSGLHPLASSLVNVSPTHNFSLSPSTLLNPTELNRDIAD 639
+ L + +GS P + + +S T S +TLL T L
Sbjct: 3842 ----------TSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPG 3891
Query: 640 SQPMSAPVASKSTVTSVSNTNYAT 663
+ S P ST + S +T
Sbjct: 3892 ASIASTPPLDTSTTFTPSTDTAST 3915
Score = 32.0 bits (71), Expect = 2.3
Identities = 45/253 (17%), Positives = 92/253 (36%), Gaps = 36/253 (14%)
Query: 432 TTTSYSPSVPVSFPGLIPSTEVKREGIQTVASQDGGSVVTFTTPVQINQYGIVQIPNSGA 491
T+T+++PS + IP + T S G ++ +TPV + +
Sbjct: 3902 TSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAV 3961
Query: 492 NSQFLNGSIGFSPLQLPPVSVAASQGNISVSSSTSDGSTFTSESTTVQQGKVFLSSLAPS 551
++ + + +P STS ST TS STT + +++ AP
Sbjct: 3962 STPVITSTELNTP-------------------STSSSSTTTSFSTTKEFTTPAMTTAAP- 4001
Query: 552 AVVYTVPNTGQTIGSVKQEGLERSLVFSQLMPVNQNAQVNANLSSENISGSGLHPLASSL 611
+ Y +T + G S + + + ++++ ++ S S++
Sbjct: 4002 -LTYVTMSTAPSTPRTTSRGCTTS---ASTLSATSTPHTSTSVTTRPVTPSSESSRPSTI 4057
Query: 612 VN-----VSPTHNFSLSPSTLLNPTELNRDIADSQPMSAPVASKSTVTSVSNTNYATLQN 666
+ P + S P+T + T +N P + + T S T++ T+
Sbjct: 4058 TSHTIPPTFPPAHSSTPPTTSASSTTVN-------PEAVTTMTTRTKPSTRTTSFPTVTT 4110
Query: 667 CSLITGQDLLSVP 679
++ T + S P
Sbjct: 4111 TAVPTNTTIKSNP 4123
>gi|239749213 PREDICTED: mucin 3B, cell surface associated, partial
[Homo sapiens]
Length = 1063
Score = 53.5 bits (127), Expect = 7e-07
Identities = 97/430 (22%), Positives = 167/430 (38%), Gaps = 50/430 (11%)
Query: 282 SETQSKSESDGNPSTEDESSKGHEDLSPHPLSSSSDGITNLSLSSHMEPVYMQQIGNAKI 341
S T++K+ S PS SS D H + +T ++SH P +M I +
Sbjct: 117 SITKTKTTSHSTPSFT--SSNSITDSRSHSTPPFTSSVTTPEMTSHNTPSFMSSIITTET 174
Query: 342 SLSSSGVLLNGSLVPASTSPVFLNGNSFIQGPSGVILNGLNVGNTQAVALNPPKMSSNIV 401
+ S+ + ++ +S + F +GV + +P +S++I
Sbjct: 175 TSHSTPSFTSSTIHSTVSSSTTAITSPFTTAETGVT----------STPSSPSSLSTDIP 224
Query: 402 SNGI-SMTDILGSTSQDVKEFKVLQSSANSATTTSYSPSVPVSFPGLIPSTEVKREGIQT 460
+ + ++T + STS S TTT+ PS+P L P+ +
Sbjct: 225 TTSLRTLTPLSLSTS-------------TSLTTTTDLPSIPTDISSL-PTPIHIISSSPS 270
Query: 461 VASQDGGSVVTFTTPVQINQYGIVQIPNSGANSQFLNGSIGFSP----LQLPPVSVAASQ 516
+ S + S+V T+P ++ + S F + SI +P Q PPV ++A+
Sbjct: 271 IQSTETSSLVGTTSPTMSTVRATLRSTENTPISSF-STSIVVTPETPTTQAPPVLMSATG 329
Query: 517 GNIS-----VSSSTSDGSTFTSESTTVQQGKVFLSSLAPSAVVYTVPNTGQTIGSVK--Q 569
S V+ + D ST T + T + S + + T +T QT S+ Q
Sbjct: 330 TQTSPVPTTVTFGSMDSSTSTLHTLTPSTALSKIMSTSQFPIPSTHSSTLQTTPSIPSLQ 389
Query: 570 EGLERSLVFSQLMPVNQNAQVNANLSS-ENISGSGL-------HPLASSLVNVSPTHNFS 621
L + F+ + NA L+S I S P ++S+ V T S
Sbjct: 390 TSLTSTSEFTTESFTRGSTSTNAILTSFSTIIWSSTPTIIMSSSPSSASITPVFATTIHS 449
Query: 622 LSPSTLLNPTELNRDIADSQPMSAPVASKSTVTSVSNTNYATLQNCSLITGQDLLSVPMT 681
+ S + TE ++ + + P S S+ TS S T+ + + IT +S+P T
Sbjct: 450 VPSSPYIFSTE---NVGSASITAFPSLSSSSTTSTSPTSSSLTTALTEITPFSYISLPST 506
Query: 682 QAALGEIVPT 691
G I T
Sbjct: 507 TPCPGTITIT 516
>gi|197100900 iroquois homeobox 2 [Homo sapiens]
Length = 471
Score = 52.8 bits (125), Expect = 1e-06
Identities = 34/103 (33%), Positives = 47/103 (45%), Gaps = 26/103 (25%)
Query: 242 YKQNRYPSPAEKRHLAKITGLSLTQVSNWFKNRRQR----------DRNPSETQSKSESD 291
+++N YP+ EK LA IT ++LTQVS WF N R+R RN SE + + E D
Sbjct: 136 HRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRNKSEDEDEDEGD 195
Query: 292 GNPSTEDESSKGHE----------------DLSPHPLSSSSDG 318
S ++ K E L+ H S+ SDG
Sbjct: 196 ATRSKDESPDKAQEGTETSAEDEGISLHVDSLTDHSCSAESDG 238
>gi|39930475 iroquois homeobox 2 [Homo sapiens]
Length = 471
Score = 52.8 bits (125), Expect = 1e-06
Identities = 34/103 (33%), Positives = 47/103 (45%), Gaps = 26/103 (25%)
Query: 242 YKQNRYPSPAEKRHLAKITGLSLTQVSNWFKNRRQR----------DRNPSETQSKSESD 291
+++N YP+ EK LA IT ++LTQVS WF N R+R RN SE + + E D
Sbjct: 136 HRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRNKSEDEDEDEGD 195
Query: 292 GNPSTEDESSKGHE----------------DLSPHPLSSSSDG 318
S ++ K E L+ H S+ SDG
Sbjct: 196 ATRSKDESPDKAQEGTETSAEDEGISLHVDSLTDHSCSAESDG 238
>gi|11386181 H2.0-like homeobox [Homo sapiens]
Length = 488
Score = 52.0 bits (123), Expect = 2e-06
Identities = 36/139 (25%), Positives = 71/139 (51%), Gaps = 8/139 (5%)
Query: 230 FKEKSRNALKELYKQNRYPSPAEKRHLAKITGLSLTQVSNWFKNRRQRDRNPSETQSKSE 289
F R L++ ++ +Y + +++ LA + GL+ QV WF+NRR + R+ E Q++ +
Sbjct: 283 FSNLQRKGLEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWRHSKEAQAQKD 342
Query: 290 SD----GNPSTEDESSKGHED-LSPHPLSSSSDGITNLSLSSHMEPVYMQQIGNAKISLS 344
D PS ++ G +D SP ++ ++ S S M P ++ ++ SL
Sbjct: 343 KDKEAGEKPSGGAPAADGEQDERSPSRSEGEAESESSDSESLDMAPSDTERTEGSERSLH 402
Query: 345 SSGVL---LNGSLVPASTS 360
+ V+ + G+L+ AS++
Sbjct: 403 QTTVIKAPVTGALITASSA 421
>gi|57863281 Meis1, myeloid ecotropic viral integration site 1
homolog 3 isoform 1 [Homo sapiens]
Length = 421
Score = 51.2 bits (121), Expect = 4e-06
Identities = 32/91 (35%), Positives = 48/91 (52%), Gaps = 2/91 (2%)
Query: 244 QNRYPSPAEKRHLAKITGLSLTQVSNWFKNRRQRDRNPSETQSKSESDGNP-STEDESSK 302
Q+ YPS +K+ LA+ TGL++ QV+NWF N R+R P QS G S E +
Sbjct: 332 QHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRTGQGAAFSPEGQPIG 391
Query: 303 GHEDLSPHPLSSSSDGITNLSLSSHMEPVYM 333
G+ + PH ++ G +SL+ E Y+
Sbjct: 392 GYTETQPH-VAVRPPGSVGMSLNLEGEWHYL 421
>gi|7705555 iroquois homeobox 4 [Homo sapiens]
Length = 519
Score = 50.1 bits (118), Expect = 8e-06
Identities = 29/81 (35%), Positives = 45/81 (55%), Gaps = 5/81 (6%)
Query: 242 YKQNRYPSPAEKRHLAKITGLSLTQVSNWFKNRRQRDRNPSE----TQSKSESDGNPSTE 297
+++N YP+ EK LA IT ++LTQVS WF N R+R + ++ ++K + P E
Sbjct: 164 HRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWPPRNKCADEKRPYAE 223
Query: 298 -DESSKGHEDLSPHPLSSSSD 317
+E G E+ PL SS +
Sbjct: 224 GEEEEGGEEEAREEPLKSSKN 244
Score = 30.4 bits (67), Expect = 6.6
Identities = 36/111 (32%), Positives = 44/111 (39%), Gaps = 15/111 (13%)
Query: 22 MESASEGQEAHREVAGGAAVGLSP----PAPAPFPLEPGDAATAAARVSGEEGAVAAAAA 77
+ SA+ G E GG V + PA A LE + A A AAAAA
Sbjct: 327 LRSAAAGPEPLPGAEGGPQVCEAKLGFVPAGASAGLEAKPRIWSLAHT-----ATAAAAA 381
Query: 78 GAAADQVQLHSELLGRHHHAAAAAAQTPLAFSPDHVACVCEALQQGGNLDR 128
+ Q + S +L R AA AA + A SP AL G LDR
Sbjct: 382 ATSLSQTEFPSCMLKRQGPAAPAAVSSAPATSPS------VALPHSGALDR 426
>gi|57863279 Meis1, myeloid ecotropic viral integration site 1
homolog 3 isoform 2 [Homo sapiens]
Length = 358
Score = 49.7 bits (117), Expect = 1e-05
Identities = 31/88 (35%), Positives = 46/88 (52%), Gaps = 2/88 (2%)
Query: 247 YPSPAEKRHLAKITGLSLTQVSNWFKNRRQRDRNPSETQSKSESDGNP-STEDESSKGHE 305
YPS +K+ LA+ TGL++ QV+NWF N R+R P QS G S E + G+
Sbjct: 272 YPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRTGQGAAFSPEGQPIGGYT 331
Query: 306 DLSPHPLSSSSDGITNLSLSSHMEPVYM 333
+ PH ++ G +SL+ E Y+
Sbjct: 332 ETQPH-VAVRPPGSVGMSLNLEGEWHYL 358
>gi|42476164 POU class 2 homeobox 1 [Homo sapiens]
Length = 743
Score = 48.1 bits (113), Expect = 3e-05
Identities = 99/439 (22%), Positives = 167/439 (38%), Gaps = 106/439 (24%)
Query: 235 RNALKELYKQNRYPSPAEKRHLAKITGLSLTQVSNWFKNRRQRDR--NPSETQSKSESDG 292
R AL++ + +N+ P+ E +A + + WF NRRQ+++ NP
Sbjct: 391 RVALEKSFLENQKPTSEEITMIADQLNMEKEVIRVWFCNRRQKEKRINP----------- 439
Query: 293 NPSTEDESSKGHEDLSPHPLSSSSDGITNLSLSSHMEPVYMQQIGNAKISLSSSGVLLNG 352
PS+ SS + + P P S + T SL ++ S++ L
Sbjct: 440 -PSSGGTSSSPIKAIFPSPTSLVA---TTPSL----------------VTSSAATTLTVS 479
Query: 353 SLVPASTSPVFLNGNSFIQGPSGVILNGLNVGNTQAVALNPPKMSSNIVSNGISMTDILG 412
++P +++ V N + G S N NT V P SS + S +S +
Sbjct: 480 PVLPLTSAAV---TNLSVTGTSDTTSN-----NTATVISTAPPASSAVTSPSLSPSPSAS 531
Query: 413 STSQDVKEFKVLQSSANSATTTSYSPSVPVSFPGLIPSTEVKREGIQTVASQDGGSVVTF 472
+++ ++S+ S T+T+ + S P+S P V G+QT A+
Sbjct: 532 ASTS--------EASSASETSTTQTTSTPLSSPLGTSQVMVTASGLQTAAA--------- 574
Query: 473 TTPVQINQYGIVQIPNSGANSQFLNGSIGFSPLQLPPVSVAASQGNISVSSSTSDGSTFT 532
G Q+P + A+ + + G +P + P AA +S++ T G
Sbjct: 575 -----AALQGAAQLP-ANASLAAMAAAAGLNPSLMAPSQFAAGGALLSLNPGTLSG---- 624
Query: 533 SESTTVQQGKVFLSSLAPSAVVYTVPNTGQTIGSVKQEGLERSLVFSQLMPVNQNAQVNA 592
+L+P+ + + T+ +++ SL + L
Sbjct: 625 --------------ALSPALM------SNSTLATIQALASGGSLPITSL-------DATG 657
Query: 593 NLSSENISGSGLHPLASSLVNVSPTHNFSLSPSTLLNPTELNRDIADSQPMSAPVASKST 652
NL N G+ A +N N SL S NP L A S SAPVAS
Sbjct: 658 NLVFANAGGAPNIVTAPLFLN---PQNLSLLTS---NPVSLVSAAAASAGNSAPVAS--- 708
Query: 653 VTSVSNTNYATLQNCSLIT 671
++T+ ++QN SL T
Sbjct: 709 -LHATSTSAESIQN-SLFT 725
>gi|51479177 iroquois homeobox protein 1 [Homo sapiens]
Length = 480
Score = 48.1 bits (113), Expect = 3e-05
Identities = 27/72 (37%), Positives = 41/72 (56%), Gaps = 7/72 (9%)
Query: 242 YKQNRYPSPAEKRHLAKITGLSLTQVSNWFKNRRQRDRNPSE----TQSKSESDG---NP 294
+++N YP+ EK LA IT ++LTQVS WF N R+R + ++ +SK + DG
Sbjct: 149 HRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKVTWGARSKDQEDGALFGS 208
Query: 295 STEDESSKGHED 306
TE + K +D
Sbjct: 209 DTEGDPEKAEDD 220
>gi|27436887 pre-B-cell leukemia homeobox 2 [Homo sapiens]
Length = 430
Score = 48.1 bits (113), Expect = 3e-05
Identities = 35/105 (33%), Positives = 51/105 (48%), Gaps = 6/105 (5%)
Query: 230 FKEKSRNALKELYKQ---NRYPSPAEKRHLAKITGLSLTQVSNWFKNRRQR-DRNPSETQ 285
F +++ L E + N YPS K LAK G++++QVSNWF N+R R +N + Q
Sbjct: 251 FSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQ 310
Query: 286 SKSESDGNPSTEDESSKGHEDLS--PHPLSSSSDGITNLSLSSHM 328
++ + + GH S P S+ S G NLS S M
Sbjct: 311 EEANIYAVKTAVSVTQGGHSRTSSPTPPSSAGSGGSFNLSGSGDM 355
>gi|139394646 iroquois homeobox protein 5 [Homo sapiens]
Length = 483
Score = 47.8 bits (112), Expect = 4e-05
Identities = 30/79 (37%), Positives = 42/79 (53%), Gaps = 11/79 (13%)
Query: 242 YKQNRYPSPAEKRHLAKITGLSLTQVSNWFKNRRQR----------DRNPSETQSKSES- 290
+++N YP+ EK LA IT ++LTQVS WF N R+R RN SE + + E+
Sbjct: 135 HRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWTPRNRSEDEEEEENI 194
Query: 291 DGNPSTEDESSKGHEDLSP 309
D + EDE K + P
Sbjct: 195 DLEKNDEDEPQKPEDKGDP 213
>gi|4505151 Meis homeobox 1 [Homo sapiens]
Length = 390
Score = 47.0 bits (110), Expect = 7e-05
Identities = 25/58 (43%), Positives = 34/58 (58%), Gaps = 1/58 (1%)
Query: 247 YPSPAEKRHLAKITGLSLTQVSNWFKNRRQRDRNPSETQS-KSESDGNPSTEDESSKG 303
YPS +K+ LA+ TGL++ QV+NWF N R+R P QS ++ S G P D G
Sbjct: 299 YPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGTPYNPDGQPMG 356
>gi|116174748 developing brain homeobox 2 [Homo sapiens]
Length = 339
Score = 46.6 bits (109), Expect = 9e-05
Identities = 21/56 (37%), Positives = 35/56 (62%)
Query: 230 FKEKSRNALKELYKQNRYPSPAEKRHLAKITGLSLTQVSNWFKNRRQRDRNPSETQ 285
F E R AL++++++ +Y S +++ LA GL +QV WF+NRR + RN E +
Sbjct: 193 FSEDQRKALEKMFQKQKYISKTDRKKLAINLGLKESQVKIWFQNRRMKWRNSKEKE 248
>gi|226371735 iroquois homeobox 3 [Homo sapiens]
Length = 501
Score = 46.2 bits (108), Expect = 1e-04
Identities = 23/69 (33%), Positives = 41/69 (59%), Gaps = 4/69 (5%)
Query: 242 YKQNRYPSPAEKRHLAKITGLSLTQVSNWFKNRRQRDRNPSE----TQSKSESDGNPSTE 297
+++N YP+ EK LA IT ++LTQVS WF N R+R + ++ +S+++ +GN
Sbjct: 149 HRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRSRTDEEGNAYGS 208
Query: 298 DESSKGHED 306
+ + E+
Sbjct: 209 EREEEDEEE 217
>gi|210147470 NK2 transcription factor related, locus 6 [Homo
sapiens]
Length = 219
Score = 46.2 bits (108), Expect = 1e-04
Identities = 32/90 (35%), Positives = 46/90 (51%), Gaps = 13/90 (14%)
Query: 207 KYRLRRKFPLPRTIWDGEETVYCFKEKSRNALKELYKQNRYPSPAEKRHLAKITGLSLTQ 266
K R RRK PR ++ + + AL+ +KQ RY S E+ HLA L+ TQ
Sbjct: 46 KARQRRK---PRVLFSQAQVL---------ALERRFKQQRYLSAPEREHLASALQLTSTQ 93
Query: 267 VSNWFKNRRQRDRNPSETQSKSESDGNPST 296
V WF+NRR + + + +S E G+P T
Sbjct: 94 VKIWFQNRRYKCKRQRQDKS-LELAGHPLT 122
>gi|28827782 zinc fingers and homeoboxes 3 [Homo sapiens]
Length = 956
Score = 46.2 bits (108), Expect = 1e-04
Identities = 20/45 (44%), Positives = 29/45 (64%)
Query: 236 NALKELYKQNRYPSPAEKRHLAKITGLSLTQVSNWFKNRRQRDRN 280
+ALK + +N++P +E HL K+TGLS +V WF +RR RN
Sbjct: 507 SALKGSFCRNQFPGQSEVEHLTKVTGLSTREVRKWFSDRRYHCRN 551
Score = 38.1 bits (87), Expect = 0.032
Identities = 33/121 (27%), Positives = 60/121 (49%), Gaps = 10/121 (8%)
Query: 230 FKEKSRNALKEL---YKQNRYPSPAEKRHLAKITGLSLTQVSNWFKNRRQRDRNPSETQS 286
+KE++ L+ L + QN P E L T ++ ++ +WF RR++ N ET+
Sbjct: 616 YKERAPEQLRALESSFAQNPLPLDEELDRLRSETKMTRREIDSWFSERRKK-VNAEETK- 673
Query: 287 KSESDGNPSTED--ESSKGHEDLSPHPLSSSSDGITNLSLSSHMEPVYMQQIGNAKISLS 344
K+E + + E+ E G EDL+ S +G + SSH+ + +++ KI+L
Sbjct: 674 KAEENASQEEEEAAEDEGGEEDLASELRVSGENGSLEMP-SSHI--LAERKVSPIKINLK 730
Query: 345 S 345
+
Sbjct: 731 N 731
Score = 30.8 bits (68), Expect = 5.0
Identities = 37/159 (23%), Positives = 67/159 (42%), Gaps = 6/159 (3%)
Query: 234 SRNALKELYKQNRYPSPAEKRHLAKITGLSLTQVSNWFKNRRQRDR---NPSETQSKSES 290
S + LK + + YP+ AE +L +T Q+ WF +R + +P E + +
Sbjct: 315 SNSFLKNSFHKFPYPTKAELCYLTVVTKYPEEQLKIWFTAQRLKQGISWSPEEIEDARKK 374
Query: 291 DGNPSTEDESSKGHEDLSPHPLSSSSDGITNLSLSSHMEPVYMQQIGNAKISLSSSGVLL 350
N + L+ PL +S+ + +L ++ V Q G L + ++
Sbjct: 375 MFNTVIQSVPQPTITVLNT-PLVASAGNVQHLIQAALPGHVVGQPEGTGGGLLVTQPLMA 433
Query: 351 NGSLVPASTSPVFLNGNSFIQGPSGVILNGLNVGNTQAV 389
NG + A++SP+ L S + P +N + T AV
Sbjct: 434 NG--LQATSSPLPLTVTSVPKQPGVAPINTVCSNTTSAV 470
Score = 30.0 bits (66), Expect = 8.6
Identities = 14/48 (29%), Positives = 26/48 (54%)
Query: 233 KSRNALKELYKQNRYPSPAEKRHLAKITGLSLTQVSNWFKNRRQRDRN 280
+ R+ L++L+ Q ++PS + + TGL +V WF + R +N
Sbjct: 774 QQRHLLRQLFVQTQWPSNQDYDSIMAQTGLPRPEVVRWFGDSRYALKN 821
>gi|152963644 paired-like homeodomain transcription factor 1 [Homo
sapiens]
Length = 314
Score = 45.8 bits (107), Expect = 2e-04
Identities = 58/241 (24%), Positives = 99/241 (41%), Gaps = 33/241 (13%)
Query: 156 AFHQGIYPELYSILESHSFESANHPLLQ-QLWYKARYTEAERARGRPLGAVDKYRLRRKF 214
AFH + LE+ + ES++ L + + + + E A G G D ++K
Sbjct: 30 AFHLARPADPREPLENSASESSDTELPEKERGGEPKGPEDSGAGGTGCGGADDPAKKKKQ 89
Query: 215 PLPRTIWDGEETVYCFKEKSRNALKELYKQNRYPSPAEKRHLAKITGLSLTQVSNWFKNR 274
RT F + L+ +++NRYP + + +A T L+ +V WFKNR
Sbjct: 90 RRQRTH---------FTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNR 140
Query: 275 RQRDRNPSETQSKSESDGN---------PSTEDESSKGH-------EDLSPHPLSSSSDG 318
R + R Q G ED + G+ + L+P PLS+ S
Sbjct: 141 RAKWRKRERNQQLDLCKGGYVPQFSGLVQPYEDVYAAGYSYNNWAAKSLAPAPLSTKS-- 198
Query: 319 ITNLSLSSHMEPVYMQQIGNAKISLSSSGVLLNGSLVPASTSPVFLNGNSFIQGPSGVIL 378
+ + M P+ Q + +A S+SS + + S+ P + + +G + I +G L
Sbjct: 199 ---FTFFNSMSPLSSQSMFSAPSSISS--MTMPSSMGPGAVPGMPNSGLNNINNLTGSSL 253
Query: 379 N 379
N
Sbjct: 254 N 254
>gi|42544241 iroquois homeobox protein 6 [Homo sapiens]
Length = 446
Score = 45.8 bits (107), Expect = 2e-04
Identities = 46/163 (28%), Positives = 71/163 (43%), Gaps = 19/163 (11%)
Query: 163 PELYSILE-SHSFESANHPLLQQLWYKARYTEAERARGR----PLGAVDKYRLRRKFPLP 217
P LY L + F+ A L Y ER G+ GAV+ R+
Sbjct: 95 PSLYGALNPQYEFKEAAGSFTSSLAQPGAYYPYERTLGQYQYERYGAVELSGAGRRKNAT 154
Query: 218 RTIWDGEETVYCFKEKSRNALKELYKQNRYPSPAEKRHLAKITGLSLTQVSNWFKNRRQR 277
R ET K A +++N YP+ EK LA IT ++LTQVS WF N R+R
Sbjct: 155 R------ETTSTLK-----AWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRR 203
Query: 278 DRNPSETQSKSESDGNPSTEDESSKGHEDLSPHPLSSSSDGIT 320
+ ++ ++ G E+ ++G E+ S L++ + +T
Sbjct: 204 LKKENKMTWAPKNKGG---EERKAEGGEEDSLGCLTADTKEVT 243
>gi|21361183 paired-like homeodomain transcription factor 2 isoform
c [Homo sapiens]
Length = 324
Score = 45.4 bits (106), Expect = 2e-04
Identities = 46/177 (25%), Positives = 81/177 (45%), Gaps = 28/177 (15%)
Query: 230 FKEKSRNALKELYKQNRYPSPAEKRHLAKITGLSLTQVSNWFKNRR----QRDRNPSETQ 285
F + L+ +++NRYP + + +A T L+ +V WFKNRR +R+RN Q
Sbjct: 99 FTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERN---QQ 155
Query: 286 SKSESDGNPSTEDESSKGHEDLSPHPLSS--SSDGITNLSLSSHMEPVYMQQIGNAKISL 343
++ +G + + ++D+ P + ++ G+T+ SLS+ P + N S
Sbjct: 156 AELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQ 215
Query: 344 SS-------SGVLLNGSLVPASTSPVFLNGNSFIQGPSGVILNGL-NVGNTQAVALN 392
S S + ++ S+VP S + G G LN L N+ N + +LN
Sbjct: 216 SMFSPPNSISSMSMSSSMVP-----------SAVTGVPGSSLNSLNNLNNLSSPSLN 261
>gi|24234711 paired-like homeodomain transcription factor 2 isoform
a [Homo sapiens]
Length = 271
Score = 45.4 bits (106), Expect = 2e-04
Identities = 46/177 (25%), Positives = 81/177 (45%), Gaps = 28/177 (15%)
Query: 230 FKEKSRNALKELYKQNRYPSPAEKRHLAKITGLSLTQVSNWFKNRR----QRDRNPSETQ 285
F + L+ +++NRYP + + +A T L+ +V WFKNRR +R+RN Q
Sbjct: 46 FTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERN---QQ 102
Query: 286 SKSESDGNPSTEDESSKGHEDLSPHPLSS--SSDGITNLSLSSHMEPVYMQQIGNAKISL 343
++ +G + + ++D+ P + ++ G+T+ SLS+ P + N S
Sbjct: 103 AELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQ 162
Query: 344 SS-------SGVLLNGSLVPASTSPVFLNGNSFIQGPSGVILNGL-NVGNTQAVALN 392
S S + ++ S+VP S + G G LN L N+ N + +LN
Sbjct: 163 SMFSPPNSISSMSMSSSMVP-----------SAVTGVPGSSLNSLNNLNNLSSPSLN 208
>gi|24234708 paired-like homeodomain transcription factor 2 isoform
b [Homo sapiens]
Length = 317
Score = 45.4 bits (106), Expect = 2e-04
Identities = 46/177 (25%), Positives = 81/177 (45%), Gaps = 28/177 (15%)
Query: 230 FKEKSRNALKELYKQNRYPSPAEKRHLAKITGLSLTQVSNWFKNRR----QRDRNPSETQ 285
F + L+ +++NRYP + + +A T L+ +V WFKNRR +R+RN Q
Sbjct: 92 FTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERN---QQ 148
Query: 286 SKSESDGNPSTEDESSKGHEDLSPHPLSS--SSDGITNLSLSSHMEPVYMQQIGNAKISL 343
++ +G + + ++D+ P + ++ G+T+ SLS+ P + N S
Sbjct: 149 AELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQ 208
Query: 344 SS-------SGVLLNGSLVPASTSPVFLNGNSFIQGPSGVILNGL-NVGNTQAVALN 392
S S + ++ S+VP S + G G LN L N+ N + +LN
Sbjct: 209 SMFSPPNSISSMSMSSSMVP-----------SAVTGVPGSSLNSLNNLNNLSSPSLN 254
>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1531
Score = 45.4 bits (106), Expect = 2e-04
Identities = 88/432 (20%), Positives = 156/432 (36%), Gaps = 59/432 (13%)
Query: 257 AKITGLSLTQVSNWFKNRRQRDRNPSETQSKSESDGNPS----TEDE----SSKGHEDL- 307
A TG T S SET + S +D + T E S++G E
Sbjct: 616 ASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTT 675
Query: 308 -----SPHPLSSSSDGITNLSLSSHMEPVYMQQIGNAKISLSSSGV-LLNGSLVPASTSP 361
S +S+ G T +S++ E + G+ + S+ G + S+ + T+
Sbjct: 676 VSATGSETTVSTEGSGTTTVSITGS-ETTKVSTTGSETTTTSTEGSEITTASITGSETTT 734
Query: 362 VFLNGN----SFIQGPSGVILNGLNVGNTQAVALNPPKMSSNIVSNGISMTDILGSTSQD 417
G+ + +G + T A + ++I+ + +M +GS +
Sbjct: 735 ASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTK 794
Query: 418 VKEFKVLQSSANSATTTSYSPSVPVSFPGLIPS--TEVKREGIQTVASQDGGSVVTFTTP 475
V S+A+S TT ++ + + S T V G +T+ + GS T TT
Sbjct: 795 V-------STASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTS 847
Query: 476 VQINQYGIVQIPNSGANSQFLNGSIGFSPLQLPPVSVAASQGNISVSSSTSDGSTFTSES 535
+ S+ S S + + ++ S T+ ST SE+
Sbjct: 848 TE--------------GSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSET 893
Query: 536 TTVQ-QGKVFLSSLAPSAVVYTVPNTGQTIGSVKQEGLE---RSLVFSQLMPVNQNAQVN 591
TT +G ++ + + TV TG + EG E S S+L V+
Sbjct: 894 TTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSET 953
Query: 592 ANLSSENISGSGLHPLASSLVNVSPTHNFSLSPSTLLNPTELNRDIADSQPMSAPVASKS 651
+S+E + + + S S + + + ST A S+ +A +
Sbjct: 954 ITVSAEGSETTTVTTMGSETTTASTAGSETTTVST-----------AGSETTTASIEGSE 1002
Query: 652 TVTSVSNTNYAT 663
T T+VS+T T
Sbjct: 1003 T-TTVSSTGSET 1013
Score = 35.0 bits (79), Expect = 0.27
Identities = 56/279 (20%), Positives = 107/279 (38%), Gaps = 30/279 (10%)
Query: 424 LQSSANSATTTSYSPSVPVSFPGLIPSTEVKREGIQ-TVASQDGGSVVTFTTPVQINQYG 482
+ S + T T S VS + +T EG + T+AS T +T + ++
Sbjct: 408 ITDSETTTTCTEGSEMTAVSTT-VFETTTASTEGSEITIASTSDSETTTAST--EGSETT 464
Query: 483 IVQIPNSGANSQFLNGSIGFSPLQLPPVSVAASQGN-----ISVSSSTSDGSTFTSESTT 537
V S + + GS + A++ G ++ S T+ ST SE+T
Sbjct: 465 TVTTAGSETKTAYTTGS---------ETTTASNTGLETTTVFTIGSDTTTASTEGSETTA 515
Query: 538 VQQ-GKVFLSSLAPSAVVYTVPNTGQTIGSVKQEGLERSLVFSQLMPVNQNAQVNANLSS 596
V G + + TV TG +V GLE + ++ + + A ++
Sbjct: 516 VSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTT 575
Query: 597 ENISGSGLHPLASSLVNVSPTHNFSLSPSTLLNPTELNRDIADSQPMSAPVASKSTVTSV 656
++ GSG ++ + + + ++S + N T ADS+ SA T T+
Sbjct: 576 DSTEGSG-----TTAASTAGSETTTVSTADSENTT---ASTADSETTSASTTGSETTTAS 627
Query: 657 SNTNYATLQNCSLITGQDLLSVPMTQAALGEIVPTAEDQ 695
+ ++ T + G + +V T + + T ++
Sbjct: 628 TTSSETTTASTE---GSETTTVSTTDSETTMVSTTGSER 663
Score = 32.0 bits (71), Expect = 2.3
Identities = 52/260 (20%), Positives = 97/260 (37%), Gaps = 22/260 (8%)
Query: 426 SSANSATTTSY---SPSVPVSFPGLIPSTEVKREGIQTVASQDGGSVVTFTTPVQINQYG 482
++A S T T+Y S + S GL +T T AS +G TT V
Sbjct: 467 TTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSE----TTAVSATGSE 522
Query: 483 IVQIPNSGANSQFLNGSIGFSPLQLPPVSVAASQGNISVSSSTSDGSTFTSESTTVQQGK 542
+ + G+ N ++ + + VS + ++++++GS T+ STT +
Sbjct: 523 MTTVSTEGSE----NTTVSTTGSETTTVSTTG----LETTTTSTEGSEMTTVSTTGAETT 574
Query: 543 VFLSSLAPSAVVYTVPNTGQTIGSVKQEGLERSLVFSQLMPVNQNAQVNANLSSENISGS 602
+ + + T + T+ + E S S+ + S+ + +
Sbjct: 575 TDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETT 634
Query: 603 GLHPLASSLVNVSPTHNFSLSPSTLLNPTELNRDIADSQ-PMSAPVASKSTVTSVSNTNY 661
S VS T S +T+++ T R I ++ + V++ + T+VS
Sbjct: 635 TASTEGSETTTVSTTD----SETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGS 690
Query: 662 ATLQNCSLITGQDLLSVPMT 681
T ITG + V T
Sbjct: 691 GT--TTVSITGSETTKVSTT 708
Score = 32.0 bits (71), Expect = 2.3
Identities = 54/293 (18%), Positives = 107/293 (36%), Gaps = 24/293 (8%)
Query: 397 SSNIVSNGISMTDILGSTSQDVKEFKVLQSSANSATTTSYSPSVPVSFPGLIPSTEVKRE 456
++ + S G T + ST+ + S + TT+ S + V G +T E
Sbjct: 1003 TTTVSSTGSETTTV--STTGTETTITSTEGSETTTVTTAGSETTAVYTTGS-ETTTTSTE 1059
Query: 457 GIQTVASQDGGSVVTFTTPVQINQYGIVQIPNSGANSQFLNGSIGFSPLQLPPVSVAASQ 516
G +T GS T + + + V SG + GS + V + S+
Sbjct: 1060 GSETTTVSTTGSETTTASTADL-ETTTVSTSGSGTTTASTAGS------ETTTVYITGSK 1112
Query: 517 GNISVSSSTSDGSTFTSESTTVQQGKVFLSSLAPSAVVYTVPNTGQTIGSVKQEGLERSL 576
++++++GS T+ STT + ++ + V+T + T+ ++ E S
Sbjct: 1113 ----TTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSA 1168
Query: 577 VFSQLMPVNQNAQVNANLSSENISGSGLHPLASSLVNVSPTHNFSLSPSTLLNPTELNRD 636
S+ + S+ + S S + + + ST + +E N
Sbjct: 1169 AGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTAST--SGSETNTA 1226
Query: 637 IADSQPMSAPVASKSTVTSV----SNTNYATLQN----CSLITGQDLLSVPMT 681
S P ++ S + S T A+ + + +TG + +V +T
Sbjct: 1227 CTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSIT 1279
>gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1521
Score = 45.4 bits (106), Expect = 2e-04
Identities = 88/432 (20%), Positives = 156/432 (36%), Gaps = 59/432 (13%)
Query: 257 AKITGLSLTQVSNWFKNRRQRDRNPSETQSKSESDGNPS----TEDE----SSKGHEDL- 307
A TG T S SET + S +D + T E S++G E
Sbjct: 616 ASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTT 675
Query: 308 -----SPHPLSSSSDGITNLSLSSHMEPVYMQQIGNAKISLSSSGV-LLNGSLVPASTSP 361
S +S+ G T +S++ E + G+ + S+ G + S+ + T+
Sbjct: 676 VSATGSETTVSTEGSGTTTVSITGS-ETTKVSTTGSETTTTSTEGSEITTASITGSETTT 734
Query: 362 VFLNGN----SFIQGPSGVILNGLNVGNTQAVALNPPKMSSNIVSNGISMTDILGSTSQD 417
G+ + +G + T A + ++I+ + +M +GS +
Sbjct: 735 ASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTK 794
Query: 418 VKEFKVLQSSANSATTTSYSPSVPVSFPGLIPS--TEVKREGIQTVASQDGGSVVTFTTP 475
V S+A+S TT ++ + + S T V G +T+ + GS T TT
Sbjct: 795 V-------STASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTS 847
Query: 476 VQINQYGIVQIPNSGANSQFLNGSIGFSPLQLPPVSVAASQGNISVSSSTSDGSTFTSES 535
+ S+ S S + + ++ S T+ ST SE+
Sbjct: 848 TE--------------GSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSET 893
Query: 536 TTVQ-QGKVFLSSLAPSAVVYTVPNTGQTIGSVKQEGLE---RSLVFSQLMPVNQNAQVN 591
TT +G ++ + + TV TG + EG E S S+L V+
Sbjct: 894 TTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSET 953
Query: 592 ANLSSENISGSGLHPLASSLVNVSPTHNFSLSPSTLLNPTELNRDIADSQPMSAPVASKS 651
+S+E + + + S S + + + ST A S+ +A +
Sbjct: 954 ITVSAEGSETTTVTTMGSETTTASTAGSETTTVST-----------AGSETTTASIEGSE 1002
Query: 652 TVTSVSNTNYAT 663
T T+VS+T T
Sbjct: 1003 T-TTVSSTGSET 1013
Score = 35.0 bits (79), Expect = 0.27
Identities = 56/279 (20%), Positives = 107/279 (38%), Gaps = 30/279 (10%)
Query: 424 LQSSANSATTTSYSPSVPVSFPGLIPSTEVKREGIQ-TVASQDGGSVVTFTTPVQINQYG 482
+ S + T T S VS + +T EG + T+AS T +T + ++
Sbjct: 408 ITDSETTTTCTEGSEMTAVSTT-VFETTTASTEGSEITIASTSDSETTTAST--EGSETT 464
Query: 483 IVQIPNSGANSQFLNGSIGFSPLQLPPVSVAASQGN-----ISVSSSTSDGSTFTSESTT 537
V S + + GS + A++ G ++ S T+ ST SE+T
Sbjct: 465 TVTTAGSETKTAYTTGS---------ETTTASNTGLETTTVFTIGSDTTTASTEGSETTA 515
Query: 538 VQQ-GKVFLSSLAPSAVVYTVPNTGQTIGSVKQEGLERSLVFSQLMPVNQNAQVNANLSS 596
V G + + TV TG +V GLE + ++ + + A ++
Sbjct: 516 VSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTT 575
Query: 597 ENISGSGLHPLASSLVNVSPTHNFSLSPSTLLNPTELNRDIADSQPMSAPVASKSTVTSV 656
++ GSG ++ + + + ++S + N T ADS+ SA T T+
Sbjct: 576 DSTEGSG-----TTAASTAGSETTTVSTADSENTT---ASTADSETTSASTTGSETTTAS 627
Query: 657 SNTNYATLQNCSLITGQDLLSVPMTQAALGEIVPTAEDQ 695
+ ++ T + G + +V T + + T ++
Sbjct: 628 TTSSETTTASTE---GSETTTVSTTDSETTMVSTTGSER 663
Score = 32.7 bits (73), Expect = 1.3
Identities = 49/285 (17%), Positives = 104/285 (36%), Gaps = 18/285 (6%)
Query: 397 SSNIVSNGISMTDILGSTSQDVKEFKVLQSSANSATTTSYSPSVPVSFPGLIPSTEVKRE 456
++ + S G T + ST+ + S + TT+ S + V G +T E
Sbjct: 1003 TTTVSSTGSETTTV--STTGTETTITSTEGSETTTVTTAGSETTAVYTTGS-ETTTTSTE 1059
Query: 457 GIQTVASQDGGSVVTFTTPVQINQYGIVQIPNSGANSQFLNGSIGFSPLQLPPVSVAASQ 516
G +T GS T + + + V SG + GS + V + S+
Sbjct: 1060 GSETTTVSTTGSETTTASTADL-ETTTVSTSGSGTTTASTAGS------ETTTVYITGSK 1112
Query: 517 GNISVSSSTSDGSTFTSESTTVQQGKVFLSSLAPSAVVYTVPNTGQTIGSVKQEGLERSL 576
++++++GS T+ STT + ++ + V+T + T+ ++ E S
Sbjct: 1113 ----TTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSA 1168
Query: 577 VFSQLMPVNQNAQVNANLSSENISGSGLHPLASSLVNVSPTHNFSLSPSTLLNPTELNRD 636
S+ + S+ + S S + + + + T + T
Sbjct: 1169 AGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSS 1228
Query: 637 IADSQPMSAPVASKSTVTSVSNTNYATLQNCSLITGQDLLSVPMT 681
+ + S++T+ S ++ + +TG + +V +T
Sbjct: 1229 AGSETNTAFIIGSETTIASTASLE----PTATSLTGSETTTVSIT 1269
Score = 32.0 bits (71), Expect = 2.3
Identities = 52/260 (20%), Positives = 97/260 (37%), Gaps = 22/260 (8%)
Query: 426 SSANSATTTSY---SPSVPVSFPGLIPSTEVKREGIQTVASQDGGSVVTFTTPVQINQYG 482
++A S T T+Y S + S GL +T T AS +G TT V
Sbjct: 467 TTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSE----TTAVSATGSE 522
Query: 483 IVQIPNSGANSQFLNGSIGFSPLQLPPVSVAASQGNISVSSSTSDGSTFTSESTTVQQGK 542
+ + G+ N ++ + + VS + ++++++GS T+ STT +
Sbjct: 523 MTTVSTEGSE----NTTVSTTGSETTTVSTTG----LETTTTSTEGSEMTTVSTTGAETT 574
Query: 543 VFLSSLAPSAVVYTVPNTGQTIGSVKQEGLERSLVFSQLMPVNQNAQVNANLSSENISGS 602
+ + + T + T+ + E S S+ + S+ + +
Sbjct: 575 TDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETT 634
Query: 603 GLHPLASSLVNVSPTHNFSLSPSTLLNPTELNRDIADSQ-PMSAPVASKSTVTSVSNTNY 661
S VS T S +T+++ T R I ++ + V++ + T+VS
Sbjct: 635 TASTEGSETTTVSTTD----SETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGS 690
Query: 662 ATLQNCSLITGQDLLSVPMT 681
T ITG + V T
Sbjct: 691 GT--TTVSITGSETTKVSTT 708
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.125 0.345
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,069,929
Number of Sequences: 37866
Number of extensions: 1349546
Number of successful extensions: 7180
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 264
Number of HSP's successfully gapped in prelim test: 185
Number of HSP's that attempted gapping in prelim test: 6304
Number of HSP's gapped (non-prelim): 933
length of query: 781
length of database: 18,247,518
effective HSP length: 110
effective length of query: 671
effective length of database: 14,082,258
effective search space: 9449195118
effective search space used: 9449195118
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.