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Search of human proteins with 14195599
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14195599 protein phosphatase 1, regulatory (inhibitor)
subunit 12B isoform d [Homo sapiens]
(224 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14195601 protein phosphatase 1, regulatory (inhibitor) subuni... 431 e-121
gi|14195599 protein phosphatase 1, regulatory (inhibitor) subuni... 431 e-121
gi|14195597 protein phosphatase 1, regulatory (inhibitor) subuni... 366 e-102
gi|4505319 protein phosphatase 1, regulatory (inhibitor) subunit... 366 e-102
gi|219842214 protein phosphatase 1, regulatory (inhibitor) subun... 165 3e-41
gi|219842212 protein phosphatase 1, regulatory (inhibitor) subun... 165 3e-41
gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit... 165 3e-41
gi|14149716 protein phosphatase 1, regulatory subunit 12C [Homo ... 86 2e-17
gi|148839339 nexilin (F actin binding protein) [Homo sapiens] 56 3e-08
gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens] 55 4e-08
gi|31982906 cingulin-like 1 [Homo sapiens] 53 2e-07
gi|15149465 caldesmon 1 isoform 5 [Homo sapiens] 52 3e-07
gi|4826657 caldesmon 1 isoform 2 [Homo sapiens] 52 3e-07
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 52 4e-07
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 52 4e-07
gi|22208850 Golgi coiled-coil protein 1 [Homo sapiens] 52 5e-07
gi|221219020 NYD-SP11 protein [Homo sapiens] 51 7e-07
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 51 7e-07
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 51 7e-07
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 51 7e-07
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 51 7e-07
gi|15149463 caldesmon 1 isoform 4 [Homo sapiens] 51 7e-07
gi|15149467 caldesmon 1 isoform 3 [Homo sapiens] 51 7e-07
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 50 1e-06
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 50 2e-06
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 50 2e-06
gi|157042792 coiled-coil domain containing 64B [Homo sapiens] 50 2e-06
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 49 3e-06
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 49 3e-06
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 49 3e-06
>gi|14195601 protein phosphatase 1, regulatory (inhibitor) subunit
12B isoform b [Homo sapiens]
Length = 998
Score = 431 bits (1107), Expect = e-121
Identities = 224/224 (100%), Positives = 224/224 (100%)
Query: 1 MDKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERL 60
MDKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERL
Sbjct: 775 MDKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERL 834
Query: 61 SRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQ 120
SRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQ
Sbjct: 835 SRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQ 894
Query: 121 KLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMK 180
KLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMK
Sbjct: 895 KLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMK 954
Query: 181 NLHQLKQIQTLKQMNEQLQAENRALTRVVARLSESIESSDTQEL 224
NLHQLKQIQTLKQMNEQLQAENRALTRVVARLSESIESSDTQEL
Sbjct: 955 NLHQLKQIQTLKQMNEQLQAENRALTRVVARLSESIESSDTQEL 998
>gi|14195599 protein phosphatase 1, regulatory (inhibitor) subunit
12B isoform d [Homo sapiens]
Length = 224
Score = 431 bits (1107), Expect = e-121
Identities = 224/224 (100%), Positives = 224/224 (100%)
Query: 1 MDKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERL 60
MDKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERL
Sbjct: 1 MDKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERL 60
Query: 61 SRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQ 120
SRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQ
Sbjct: 61 SRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQ 120
Query: 121 KLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMK 180
KLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMK
Sbjct: 121 KLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMK 180
Query: 181 NLHQLKQIQTLKQMNEQLQAENRALTRVVARLSESIESSDTQEL 224
NLHQLKQIQTLKQMNEQLQAENRALTRVVARLSESIESSDTQEL
Sbjct: 181 NLHQLKQIQTLKQMNEQLQAENRALTRVVARLSESIESSDTQEL 224
>gi|14195597 protein phosphatase 1, regulatory (inhibitor) subunit
12B isoform c [Homo sapiens]
Length = 208
Score = 366 bits (940), Expect = e-102
Identities = 193/214 (90%), Positives = 201/214 (93%), Gaps = 6/214 (2%)
Query: 1 MDKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERL 60
MDKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERL
Sbjct: 1 MDKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERL 60
Query: 61 SRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQ 120
SRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQ
Sbjct: 61 SRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQ 120
Query: 121 KLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMK 180
KLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMK
Sbjct: 121 KLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMK 180
Query: 181 NLHQLKQIQTLKQMNEQLQAENRALTRVVARLSE 214
L + LK N++L+ EN AL RV+++LS+
Sbjct: 181 VLTE------LKSDNQRLKDENGALIRVISKLSK 208
>gi|4505319 protein phosphatase 1, regulatory (inhibitor) subunit
12B isoform a [Homo sapiens]
Length = 982
Score = 366 bits (940), Expect = e-102
Identities = 193/214 (90%), Positives = 201/214 (93%), Gaps = 6/214 (2%)
Query: 1 MDKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERL 60
MDKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERL
Sbjct: 775 MDKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERL 834
Query: 61 SRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQ 120
SRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQ
Sbjct: 835 SRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQ 894
Query: 121 KLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMK 180
KLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMK
Sbjct: 895 KLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMK 954
Query: 181 NLHQLKQIQTLKQMNEQLQAENRALTRVVARLSE 214
L + LK N++L+ EN AL RV+++LS+
Sbjct: 955 VLTE------LKSDNQRLKDENGALIRVISKLSK 982
>gi|219842214 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform b [Homo sapiens]
Length = 943
Score = 165 bits (417), Expect = 3e-41
Identities = 102/221 (46%), Positives = 140/221 (63%), Gaps = 25/221 (11%)
Query: 5 ENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDE--------TDGSEEVKETW 56
+ EE E S+ SIRERRRP+E+RR TG++FWT+D DE T+ KET
Sbjct: 737 KREEEKEGEDKSQPKSIRERRRPREKRRSTGVSFWTQDSDENEQEQQSDTEEGSNKKETQ 796
Query: 57 HERLSRLESGGSNPTTSDSYGDRASARARREAREARL---ATLTSRVEEDSNRDYKKLYE 113
+ +SR E T+S S GDR + R + L +SR+E+D + D+KKLYE
Sbjct: 797 TDSISRYE------TSSTSAGDRYDSLLGRSGSYSYLEERKPYSSRLEKDDSTDFKKLYE 850
Query: 114 SALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMS 173
L EN+KLK +L + +EL D+K +LEK A Q+QE+ +DR S+LEMEKRERRALER++S
Sbjct: 851 QILAENEKLKAQLHDTNMELTDLKLQLEK-ATQRQERFADR-SLLEMEKRERRALERRIS 908
Query: 174 EMEEEMKNLHQLKQIQTLKQMNEQLQAENRALTRVVARLSE 214
EMEEE LK + LK N++L+ EN AL RV+++LS+
Sbjct: 909 EMEEE------LKMLPDLKADNQRLKDENGALIRVISKLSK 943
>gi|219842212 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform a [Homo sapiens]
Length = 1030
Score = 165 bits (417), Expect = 3e-41
Identities = 102/221 (46%), Positives = 140/221 (63%), Gaps = 25/221 (11%)
Query: 5 ENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDE--------TDGSEEVKETW 56
+ EE E S+ SIRERRRP+E+RR TG++FWT+D DE T+ KET
Sbjct: 824 KREEEKEGEDKSQPKSIRERRRPREKRRSTGVSFWTQDSDENEQEQQSDTEEGSNKKETQ 883
Query: 57 HERLSRLESGGSNPTTSDSYGDRASARARREAREARL---ATLTSRVEEDSNRDYKKLYE 113
+ +SR E T+S S GDR + R + L +SR+E+D + D+KKLYE
Sbjct: 884 TDSISRYE------TSSTSAGDRYDSLLGRSGSYSYLEERKPYSSRLEKDDSTDFKKLYE 937
Query: 114 SALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMS 173
L EN+KLK +L + +EL D+K +LEK A Q+QE+ +DR S+LEMEKRERRALER++S
Sbjct: 938 QILAENEKLKAQLHDTNMELTDLKLQLEK-ATQRQERFADR-SLLEMEKRERRALERRIS 995
Query: 174 EMEEEMKNLHQLKQIQTLKQMNEQLQAENRALTRVVARLSE 214
EMEEE LK + LK N++L+ EN AL RV+++LS+
Sbjct: 996 EMEEE------LKMLPDLKADNQRLKDENGALIRVISKLSK 1030
>gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit 12A
isoform a [Homo sapiens]
Length = 1030
Score = 165 bits (417), Expect = 3e-41
Identities = 102/221 (46%), Positives = 140/221 (63%), Gaps = 25/221 (11%)
Query: 5 ENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDE--------TDGSEEVKETW 56
+ EE E S+ SIRERRRP+E+RR TG++FWT+D DE T+ KET
Sbjct: 824 KREEEKEGEDKSQPKSIRERRRPREKRRSTGVSFWTQDSDENEQEQQSDTEEGSNKKETQ 883
Query: 57 HERLSRLESGGSNPTTSDSYGDRASARARREAREARL---ATLTSRVEEDSNRDYKKLYE 113
+ +SR E T+S S GDR + R + L +SR+E+D + D+KKLYE
Sbjct: 884 TDSISRYE------TSSTSAGDRYDSLLGRSGSYSYLEERKPYSSRLEKDDSTDFKKLYE 937
Query: 114 SALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMS 173
L EN+KLK +L + +EL D+K +LEK A Q+QE+ +DR S+LEMEKRERRALER++S
Sbjct: 938 QILAENEKLKAQLHDTNMELTDLKLQLEK-ATQRQERFADR-SLLEMEKRERRALERRIS 995
Query: 174 EMEEEMKNLHQLKQIQTLKQMNEQLQAENRALTRVVARLSE 214
EMEEE LK + LK N++L+ EN AL RV+++LS+
Sbjct: 996 EMEEE------LKMLPDLKADNQRLKDENGALIRVISKLSK 1030
>gi|14149716 protein phosphatase 1, regulatory subunit 12C [Homo
sapiens]
Length = 782
Score = 86.3 bits (212), Expect = 2e-17
Identities = 51/131 (38%), Positives = 82/131 (62%), Gaps = 7/131 (5%)
Query: 84 ARREAREARLATLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQLELADIKSKLEKV 143
ARR+ + L E+ + ++ LY EN++L+ L E L LA +K +LE+
Sbjct: 659 ARRQRWQRDLNPEPEPESEEPDGGFRTLYAELRRENERLREALTETTLRLAQLKVELER- 717
Query: 144 AQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKNLHQLKQIQTLKQMNEQLQAENR 203
A Q+QE+ ++R ++LE+E+ ERRALERK +E+EEE LK + L+ N++L+ EN
Sbjct: 718 ATQRQERFAERPALLELERFERRALERKAAELEEE------LKALSDLRADNQRLKDENA 771
Query: 204 ALTRVVARLSE 214
AL RV+++LS+
Sbjct: 772 ALIRVISKLSK 782
>gi|148839339 nexilin (F actin binding protein) [Homo sapiens]
Length = 675
Score = 55.8 bits (133), Expect = 3e-08
Identities = 54/219 (24%), Positives = 101/219 (46%), Gaps = 23/219 (10%)
Query: 3 KNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLSR 62
+ EN + +E++ KRL E +R E R +N +++E + ++ + + +
Sbjct: 258 RQENRKKQAEEEARKRLE--EEKRAFEEARRQMVN----EDEENQDTAKIFKGYRPGKLK 311
Query: 63 LESGGSNPTTSDSYGDRASARARREAREARLATLTSR----VEEDSNRDYKKLYESALTE 118
L + +A ARR E + A +R V++DS YK + + LT
Sbjct: 312 LSFEEMERQRREDEKRKAEEEARRRIEEEKKAFAEARRNMVVDDDSPEMYKTISQEFLTP 371
Query: 119 NQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEE 178
KL+ +E +K K+E ++K+ +R LEMEK+E L ++M E EEE
Sbjct: 372 G-KLEINFEEL------LKQKME---EEKRRTEEERKHKLEMEKQEFEQLRQEMGEEEEE 421
Query: 179 MKNLHQLKQIQTLKQMNE--QLQAEN-RALTRVVARLSE 214
+ ++ + L ++ +QA+N ++ + +LSE
Sbjct: 422 NETFGLSREYEELIKLKRSGSIQAKNLKSKFEKIGQLSE 460
Score = 32.0 bits (71), Expect = 0.44
Identities = 25/148 (16%), Positives = 66/148 (44%), Gaps = 5/148 (3%)
Query: 41 KDEDETDGSEEVKETWHERLSRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRV 100
K E S+ V +T+ +L + + + +R R+R E + + + R
Sbjct: 7 KAEILLSSSKPVPKTYVPKLGKGDVKDKFEAMQRAREERNQRRSRDEKQRRKEQYIRERE 66
Query: 101 EEDSNRDYKKLYESALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEK-----TSDRS 155
++ K++ S E+ K + +K + ++ +Q+QE+ +R
Sbjct: 67 WNRRKQEIKEMLASDDEEDVSSKVEKAYVPKLTGTVKGRFAEMEKQRQEEQRKRTEEERK 126
Query: 156 SVLEMEKRERRALERKMSEMEEEMKNLH 183
+E + E+R ++R++++ E++++++
Sbjct: 127 RRIEQDMLEKRKIQRELAKRAEQIEDIN 154
Score = 28.9 bits (63), Expect = 3.7
Identities = 42/233 (18%), Positives = 98/233 (42%), Gaps = 42/233 (18%)
Query: 18 RLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLSRLESGGSNPTTSDSY- 76
R + E++R +E+R+ T + E + +++ +R ++E + T S S
Sbjct: 105 RFAEMEKQRQEEQRKRTEEERKRRIEQDMLEKRKIQRELAKRAEQIEDINNTGTESASEE 164
Query: 77 GD-------------RASARARR---EAREARLATLTSRVEEDSNRDYKKLYES------ 114
GD + S + ++ + + R + EED Y++ S
Sbjct: 165 GDDSLLITVVPVKSYKTSGKMKKNFEDLEKEREEKERIKYEEDKRIRYEEQRPSLKEAKC 224
Query: 115 -ALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSV-----LEMEKRERRAL 168
+L + +++++ ++ L +K E++ +Q+QE ++ LE EKR
Sbjct: 225 LSLVMDDEIESEAKKESLSPGKLKLTFEELERQRQENRKKQAEEEARKRLEEEKRAFEEA 284
Query: 169 ERKMSEMEEEMKNLHQL-------------KQIQTLKQMNEQLQAENRALTRV 208
R+M +EE ++ ++ ++++ ++ +E+ +AE A R+
Sbjct: 285 RRQMVNEDEENQDTAKIFKGYRPGKLKLSFEEMERQRREDEKRKAEEEARRRI 337
Score = 28.5 bits (62), Expect = 4.9
Identities = 39/187 (20%), Positives = 74/187 (39%), Gaps = 43/187 (22%)
Query: 3 KNENEEADLDEQSSKRLSIRERRRPKERRRGTGIN-------------FWTKDEDETDGS 49
+ E+E+ +E++ +R+ E++ E RR ++ F T + E +
Sbjct: 321 RREDEKRKAEEEARRRIE-EEKKAFAEARRNMVVDDDSPEMYKTISQEFLTPGKLEINFE 379
Query: 50 EEVKETWHERLSRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDY- 108
E +K+ E R E + + E +E EE+ N +
Sbjct: 380 ELLKQKMEEEKRRTE-------------EERKHKLEMEKQEFEQLRQEMGEEEEENETFG 426
Query: 109 -KKLYESALTENQKLKTKLQEAQLELADIKSKLEKVAQ-------QKQEKTSDRSSVLEM 160
+ YE + KLK + ++ ++KSK EK+ Q +K E+ R +++
Sbjct: 427 LSREYEELI----KLK---RSGSIQAKNLKSKFEKIGQLSEKEIQKKIEEERARRRAIDL 479
Query: 161 EKRERRA 167
E +ER A
Sbjct: 480 EIKEREA 486
>gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens]
Length = 285
Score = 55.5 bits (132), Expect = 4e-08
Identities = 61/236 (25%), Positives = 112/236 (47%), Gaps = 30/236 (12%)
Query: 1 MDKNENEEADLD--EQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHE 58
+D+ E EA+ E+ SK+L E +++ +GT EDE D E + E
Sbjct: 20 LDRAEQAEAEQKQAEERSKQLE-DELAAMQKKLKGT--------EDELDKYSEALKDAQE 70
Query: 59 RLSRLESGGSNPTTSDSYGDRASARARREAREA--RLATLTSRVEE------DSNRDYKK 110
+L E ++ + +R E A RLAT ++EE +S R K
Sbjct: 71 KLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKV 130
Query: 111 LYESALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLE--MEKRERRA- 167
+ AL + +K++ LQE QL+ A + + A +K E+ + + ++E +E+ E RA
Sbjct: 131 IENRALKDEEKME--LQEIQLKEA---KHIAEEADRKYEEVARKLVIIEGDLERTEERAE 185
Query: 168 -LERKMSEMEEEMKNLHQLKQIQTLKQMNEQLQAENRALTRVVARLSESIESSDTQ 222
E K SE+EEE+KN+ +++L+ E+ + + L++ ++ ++T+
Sbjct: 186 LAESKCSELEEELKNV--TNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETR 239
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 53.1 bits (126), Expect = 2e-07
Identities = 40/145 (27%), Positives = 73/145 (50%), Gaps = 12/145 (8%)
Query: 87 EAREARLATLTS----RVEEDSNRDYKKLYESALTENQKLKTKLQEAQLEL---ADIKSK 139
EA ++RL + R+ E+ RDY++ + ALT+ Q L+ L++ + EL + +K
Sbjct: 999 EAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDD 1058
Query: 140 LEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKNL-HQLKQIQTLKQMNE-- 196
++ +Q ++K S LE E+ L ++S E+M+ L ++L Q + +Q E
Sbjct: 1059 RSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQERAARQDLECD 1118
Query: 197 --QLQAENRALTRVVARLSESIESS 219
L+ +N+ L + L S SS
Sbjct: 1119 KISLERQNKDLKSRIIHLEGSYRSS 1143
Score = 36.2 bits (82), Expect = 0.023
Identities = 34/136 (25%), Positives = 62/136 (45%), Gaps = 31/136 (22%)
Query: 107 DYKKLYESALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERR 166
+ + + + EN L+ +L+E++ EL + LE++ Q K E+ E + E R
Sbjct: 653 ELRSQHNEKVEENSTLQQRLEESEGEL---RKNLEELFQVKMER--------EQHQTEIR 701
Query: 167 ALERKMSEMEEEM---------------KNLHQLKQ-IQTL----KQMNEQLQAENRALT 206
L+ ++SEM +E+ + L Q KQ +Q L ++ + L+ R LT
Sbjct: 702 DLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELT 761
Query: 207 RVVARLSESIESSDTQ 222
+ L E + S D +
Sbjct: 762 ALKGALKEEVSSHDQE 777
>gi|15149465 caldesmon 1 isoform 5 [Homo sapiens]
Length = 532
Score = 52.4 bits (124), Expect = 3e-07
Identities = 56/198 (28%), Positives = 90/198 (45%), Gaps = 33/198 (16%)
Query: 3 KNENEEADLDEQSSKRLSIRER----------RRPKERRRGTGINFWTKDEDETDGSEEV 52
K + E+ + +E+ KR SI E + PKE + +F + + T+ +
Sbjct: 179 KEDKEKEEEEEEKPKRGSIGENQIKDEKIKKDKEPKEEVK----SFMDRKKGFTEVKSQN 234
Query: 53 KETWHERLSRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLY 112
E +L E+ S P G RAS + EA A R+EE R
Sbjct: 235 GEFMTHKLKHTENTFSRP------GGRASVDTK-EAEGAPQVEAGKRLEELRRRRG---- 283
Query: 113 ESALTENQKLKTKLQEAQLELADIKSK-------LEKVAQQKQEKTSDRSSVLEMEKRE- 164
E+ E +KLK K QEA LEL ++K K LE+ Q+++++ +DR E EKR
Sbjct: 284 ETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRL 343
Query: 165 RRALERKMSEMEEEMKNL 182
+ +ER+ +E E+ + +
Sbjct: 344 KEEIERRRAEAAEKRQKM 361
Score = 30.4 bits (67), Expect = 1.3
Identities = 26/144 (18%), Positives = 57/144 (39%), Gaps = 17/144 (11%)
Query: 73 SDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQLE 132
+D + A+ RR AR+ RL D ++ +++ KT Q+E
Sbjct: 24 NDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVE 83
Query: 133 LADIKSKLEKVAQQKQEKTSDRSSVLEMEKR-----------------ERRALERKMSEM 175
D + LE++A++++ + LE +K + E + +E
Sbjct: 84 GDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEK 143
Query: 176 EEEMKNLHQLKQIQTLKQMNEQLQ 199
EE+ ++ + +I+ + + + Q
Sbjct: 144 EEKSESRQERYEIEETETVTKSYQ 167
>gi|4826657 caldesmon 1 isoform 2 [Homo sapiens]
Length = 538
Score = 52.4 bits (124), Expect = 3e-07
Identities = 56/198 (28%), Positives = 90/198 (45%), Gaps = 33/198 (16%)
Query: 3 KNENEEADLDEQSSKRLSIRER----------RRPKERRRGTGINFWTKDEDETDGSEEV 52
K + E+ + +E+ KR SI E + PKE + +F + + T+ +
Sbjct: 185 KEDKEKEEEEEEKPKRGSIGENQIKDEKIKKDKEPKEEVK----SFMDRKKGFTEVKSQN 240
Query: 53 KETWHERLSRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLY 112
E +L E+ S P G RAS + EA A R+EE R
Sbjct: 241 GEFMTHKLKHTENTFSRP------GGRASVDTK-EAEGAPQVEAGKRLEELRRRRG---- 289
Query: 113 ESALTENQKLKTKLQEAQLELADIKSK-------LEKVAQQKQEKTSDRSSVLEMEKRE- 164
E+ E +KLK K QEA LEL ++K K LE+ Q+++++ +DR E EKR
Sbjct: 290 ETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRL 349
Query: 165 RRALERKMSEMEEEMKNL 182
+ +ER+ +E E+ + +
Sbjct: 350 KEEIERRRAEAAEKRQKM 367
Score = 32.7 bits (73), Expect = 0.26
Identities = 32/173 (18%), Positives = 69/173 (39%), Gaps = 18/173 (10%)
Query: 44 DETDGSEEVKETWHERLSRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEED 103
D+ + E++ E + RLE+ +D + A+ RR AR+ RL
Sbjct: 2 DDFERRRELRRQKREEM-RLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLG 60
Query: 104 SNRDYKKLYESALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKR 163
D ++ +++ KT Q+E D + LE++A++++ + LE +K
Sbjct: 61 QVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKE 120
Query: 164 -----------------ERRALERKMSEMEEEMKNLHQLKQIQTLKQMNEQLQ 199
+ E + +E EE+ ++ + +I+ + + + Q
Sbjct: 121 FDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQ 173
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 52.0 bits (123), Expect = 4e-07
Identities = 57/224 (25%), Positives = 100/224 (44%), Gaps = 22/224 (9%)
Query: 3 KNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLSR 62
K E E +++++ +R RER R +ERR ++ + E KE ER
Sbjct: 297 KKEKERQEIEKERRERE--RERERERERRE--------REREREREREREKEKERERERE 346
Query: 63 LESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQKL 122
+ D DR R R R + SR E S RD ++ E E ++
Sbjct: 347 RDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKS-RDRERERE---RERERE 402
Query: 123 KTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEME----EE 178
+ + +E + E + + + E+ +++++K DR E + ERR LERK+ E E E
Sbjct: 403 RERERERERE-REREREREREREREKDKKRDREED-EEDAYERRKLERKLREKEAAYQER 460
Query: 179 MKN--LHQLKQIQTLKQMNEQLQAENRALTRVVARLSESIESSD 220
+KN + + K+ + ++ E+ + R + + RL E +E D
Sbjct: 461 LKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYD 504
Score = 49.3 bits (116), Expect = 3e-06
Identities = 46/195 (23%), Positives = 78/195 (40%), Gaps = 6/195 (3%)
Query: 2 DKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLS 61
++ E + E+ +R RER + KER R +D D E ++ ER
Sbjct: 313 ERERERERERREREREREREREREKEKERERER-----ERDRDRDRTKERDRDRDRERDR 367
Query: 62 RLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQK 121
+ S+ D R +R R RE R E ++ E +K
Sbjct: 368 DRDRERSSDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREK 427
Query: 122 LKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKN 181
K + +E E A + KLE+ ++K+ +R E+ +R++ K +E EEE +
Sbjct: 428 DKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRR 487
Query: 182 LHQLKQIQTLKQMNE 196
K+ + LK+ E
Sbjct: 488 -EMAKEAKRLKEFLE 501
Score = 43.1 bits (100), Expect = 2e-04
Identities = 53/214 (24%), Positives = 86/214 (40%), Gaps = 48/214 (22%)
Query: 3 KNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSE---------EVK 53
+ E E E+ +R RER R K+++R ++EDE D E E +
Sbjct: 402 EREREREREREREREREREREREREKDKKRD-------REEDEEDAYERRKLERKLREKE 454
Query: 54 ETWHERLSRLESGGSNPTTS-DSYGDRASARARREAREA-RLATLTSRVEEDSN------ 105
+ ERL E T + +R R R A+EA RL ++D +
Sbjct: 455 AAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYR 514
Query: 106 --------RDYKKLYESALTENQKLKTKLQE--------------AQLELADIKSKLEKV 143
RD +K E+ + ++ K +L+E A+L+ + +++ +
Sbjct: 515 GSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQ 574
Query: 144 AQQKQEKTSDRSSVLEMEKRERRALERKMSEMEE 177
Q KQE S+ + EK E+R E M E EE
Sbjct: 575 PQIKQEPESEEEEEEKQEKEEKR--EEPMEEEEE 606
Score = 38.9 bits (89), Expect = 0.004
Identities = 47/225 (20%), Positives = 90/225 (40%), Gaps = 15/225 (6%)
Query: 2 DKNENEEADLD---EQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHE 58
D++ + E D E+ +R RER R +ER R + E E D + +E +
Sbjct: 380 DRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEED 439
Query: 59 RLSRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTE 118
R + +Y +R RE ++ R + EE+ R+ K E
Sbjct: 440 AYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAK-------E 492
Query: 119 NQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEE 178
++LK L++ + D K Q++ DR +E ++R+R+ + ++ E+ +
Sbjct: 493 AKRLKEFLEDYDDDRDDPKYYRGSALQKRLR---DREKEMEADERDRKREKEELEEIRQR 549
Query: 179 MKNLHQLKQIQTLKQMNEQLQAENRALTRVVARLSESIESSDTQE 223
+ L++M + +AE R ++ E + QE
Sbjct: 550 LLAEGHPDPDAELQRMEQ--EAERRRQPQIKQEPESEEEEEEKQE 592
Score = 32.3 bits (72), Expect = 0.34
Identities = 44/223 (19%), Positives = 75/223 (33%), Gaps = 47/223 (21%)
Query: 2 DKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLS 61
D ++ E + ++ +R I + RR +ER R E E + E +E ER
Sbjct: 286 DTHKKLEEEKGKKEKERQEIEKERRERERER----------ERERERRERERERERERER 335
Query: 62 RLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQK 121
E D DR R R RE D +RD ++
Sbjct: 336 EKEKERERERERDRDRDRTKERDRDRDRE-----------RDRDRDRER----------- 373
Query: 122 LKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKN 181
S K + +EK+ DR E E+ R ER+ E +
Sbjct: 374 ---------------SSDRNKDRSRSREKSRDRERERERERERERERERERERERERERE 418
Query: 182 LHQLKQIQTLKQMNEQLQAENRALTRVVARLSESIESSDTQEL 224
+ ++ + K+ + + E+ R + R E++ + L
Sbjct: 419 REREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERL 461
Score = 30.0 bits (66), Expect = 1.7
Identities = 23/99 (23%), Positives = 45/99 (45%), Gaps = 2/99 (2%)
Query: 124 TKLQEAQLELADIKSKLEKVAQQ--KQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKN 181
+K ++ +L + K K EK Q+ K+ + +R E E+RER + E E+E +
Sbjct: 282 SKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKER 341
Query: 182 LHQLKQIQTLKQMNEQLQAENRALTRVVARLSESIESSD 220
+ ++ + + E+ + +R R R S + D
Sbjct: 342 ERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKD 380
Score = 27.7 bits (60), Expect = 8.3
Identities = 42/184 (22%), Positives = 78/184 (42%), Gaps = 22/184 (11%)
Query: 8 EADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLSRLESGG 67
+A LDE +K+ + RP+ T + DE ET +++ + E L R S
Sbjct: 166 KAQLDEWKAKKKASNGNARPETV---TNDDEEALDE-ETKRRDQMIKGAIEVLIREYSSE 221
Query: 68 SNPTTSDSYGDRASARARREARE--------ARLATLTSRVEEDSN-----RDYKKLYES 114
N + +S D + ++E +E A L +ED N D + L
Sbjct: 222 LNAPSQES--DSHPRKKKKEKKEDIFRRFPVAPLIPYPLITKEDINAIEMEEDKRDLISR 279
Query: 115 ALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSE 174
+++ + KL+E + + + ++EK +++E+ +R E +RER + E
Sbjct: 280 EISKFRDTHKKLEEEKGKKEKERQEIEK---ERRERERERERERERRERERERERERERE 336
Query: 175 MEEE 178
E+E
Sbjct: 337 KEKE 340
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 52.0 bits (123), Expect = 4e-07
Identities = 48/204 (23%), Positives = 94/204 (46%), Gaps = 12/204 (5%)
Query: 7 EEADLDEQSSKRLSIRERRRPKERRRGTG-INFWTKDEDETDGSEEVKETWHERLSRLES 65
EE + + ++S E ++ +ER +G+ I+ K E EE KE +RLE+
Sbjct: 221 EETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKME------EEDKERAEAERARLEA 274
Query: 66 GGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQKLKTK 125
++ A RAR EA E A R E + ++ + A E Q++K +
Sbjct: 275 EERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEE 334
Query: 126 LQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKNLHQL 185
+ A E IK + ++ A+++Q + E E++ RA E + +++EE+ +N
Sbjct: 335 EKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAE-ERQRARAEEEEKAKVEEQKRN---- 389
Query: 186 KQIQTLKQMNEQLQAENRALTRVV 209
KQ++ K ++ + + + + +
Sbjct: 390 KQLEEKKHAMQETKIKGEKVEQKI 413
Score = 51.2 bits (121), Expect = 7e-07
Identities = 49/216 (22%), Positives = 98/216 (45%), Gaps = 12/216 (5%)
Query: 1 MDKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDED-ETDGSEEVKETWHER 59
+ E ++ + EQ S +S E+ +++ R + E+ E +E+ K+ ER
Sbjct: 233 ISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADER 292
Query: 60 LSRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTEN 119
+R+E+ + A R R E R A R++E+ R A E
Sbjct: 293 -ARIEAE-EKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKR--------AAEER 342
Query: 120 QKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRER-RALERKMSEMEEE 178
Q++K + + A E IK + ++ A+++Q ++ ++E+++R + LE K M+E
Sbjct: 343 QRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQET 402
Query: 179 MKNLHQLKQIQTLKQMNEQLQAENRALTRVVARLSE 214
+++Q K +NE+ E++ T V+ + E
Sbjct: 403 KIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGE 438
Score = 51.2 bits (121), Expect = 7e-07
Identities = 51/189 (26%), Positives = 88/189 (46%), Gaps = 23/189 (12%)
Query: 2 DKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLS 61
+K + ++ ++ K I++ + PKE + +F + + T+ + E +L
Sbjct: 449 EKLQEDKPTFKKEEIKDEKIKKDKEPKEEVK----SFMDRKKGFTEVKSQNGEFMTHKLK 504
Query: 62 RLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQK 121
E+ S P G RAS + EA A R+EE R E+ E +K
Sbjct: 505 HTENTFSRP------GGRASVDTK-EAEGAPQVEAGKRLEELRRRRG----ETESEEFEK 553
Query: 122 LKTKLQEAQLELADIKSK-------LEKVAQQKQEKTSDRSSVLEMEKRE-RRALERKMS 173
LK K QEA LEL ++K K LE+ Q+++++ +DR E EKR + +ER+ +
Sbjct: 554 LKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRA 613
Query: 174 EMEEEMKNL 182
E E+ + +
Sbjct: 614 EAAEKRQKM 622
Score = 40.4 bits (93), Expect = 0.001
Identities = 50/256 (19%), Positives = 103/256 (40%), Gaps = 35/256 (13%)
Query: 2 DKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLS 61
D ENE + +E+S R E + + N W +D +E ++ KE E
Sbjct: 140 DTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDW-RDAEENKKEDKEKEEEEEEKP 198
Query: 62 RLESGGSNPT---TSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKL-YESALT 117
+ S G N + + + ++++ + EE+ + ++ + +
Sbjct: 199 KRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKME 258
Query: 118 ENQKLKTKLQEAQLE--------------LADIKSKLE---KVAQQKQEK--TSDRSSVL 158
E K + + + A+LE +AD ++++E K A Q++E+ +R +
Sbjct: 259 EEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMR 318
Query: 159 EMEKR-----------ERRALERKMSEMEEEMKNLHQLKQIQTLKQMNEQLQAENRALTR 207
E EKR E+RA E + EEE + + ++I+ ++ + + RA
Sbjct: 319 EEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEE 378
Query: 208 VVARLSESIESSDTQE 223
A++ E + +E
Sbjct: 379 EKAKVEEQKRNKQLEE 394
Score = 39.3 bits (90), Expect = 0.003
Identities = 44/199 (22%), Positives = 81/199 (40%), Gaps = 27/199 (13%)
Query: 3 KNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLSR 62
K +E A ++ + RERR +ER R E+E +EE +R+
Sbjct: 287 KIADERARIEAEEKAAAQERERREAEERER--------MREEEKRAAEE-----RQRIKE 333
Query: 63 LESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQKL 122
E + ++ +A R+ +E R E+ R + E A E QK
Sbjct: 334 EEKRAAEERQRIKEEEKRAAEERQRIKEEE-----KRAAEERQRARAEEEEKAKVEEQKR 388
Query: 123 KTKLQEAQLELADIKSKLEKVAQ---------QKQEKTSDRSSVLEMEKRERRALERKMS 173
+L+E + + + K K EKV Q +K ++ +++VL+ + E+ +
Sbjct: 389 NKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKR 448
Query: 174 EMEEEMKNLHQLKQIQTLK 192
E +E K + ++I+ K
Sbjct: 449 EKLQEDKPTFKKEEIKDEK 467
Score = 32.7 bits (73), Expect = 0.26
Identities = 32/173 (18%), Positives = 69/173 (39%), Gaps = 18/173 (10%)
Query: 44 DETDGSEEVKETWHERLSRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEED 103
D+ + E++ E + RLE+ +D + A+ RR AR+ RL
Sbjct: 2 DDFERRRELRRQKREEM-RLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLG 60
Query: 104 SNRDYKKLYESALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKR 163
D ++ +++ KT Q+E D + LE++A++++ + LE +K
Sbjct: 61 QVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKE 120
Query: 164 -----------------ERRALERKMSEMEEEMKNLHQLKQIQTLKQMNEQLQ 199
+ E + +E EE+ ++ + +I+ + + + Q
Sbjct: 121 FDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQ 173
Score = 28.5 bits (62), Expect = 4.9
Identities = 33/160 (20%), Positives = 63/160 (39%), Gaps = 6/160 (3%)
Query: 2 DKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVK-ETWHERL 60
+K EE ++ KR + +R +E +R K+E++ E + E
Sbjct: 321 EKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEK 380
Query: 61 SRLESGGSNPTTSDSYGDRASARARREAREARLA---TLTSRVEEDSNRD--YKKLYESA 115
+++E N + + + E E ++ + +ED + KK E
Sbjct: 381 AKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEK 440
Query: 116 LTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRS 155
T+ Q + KLQE + + K EK+ + K+ K +S
Sbjct: 441 GTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKS 480
>gi|22208850 Golgi coiled-coil protein 1 [Homo sapiens]
Length = 775
Score = 51.6 bits (122), Expect = 5e-07
Identities = 44/143 (30%), Positives = 67/143 (46%), Gaps = 14/143 (9%)
Query: 72 TSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQL 131
T ++ RA A + E E + LT VEE K ++ E + +LQE Q
Sbjct: 271 TREALAGRAYAAEQMEGFELQTKQLTREVEE-----LKSELQAIRDEKNQPDPRLQELQE 325
Query: 132 ELADIKSKLEKVAQQKQEKTSDRSSVL----EMEKRERRALERKMSEMEEEMKNLHQLKQ 187
E A +KS + QQ+ KT+ L ++E++ ALE ++SE+ E + + KQ
Sbjct: 326 EAARLKSHFQAQLQQEMRKTALAEDQLRQQSQVEEQRVAALENQISEVSELLGTYEKAKQ 385
Query: 188 -----IQTLKQMNEQLQAENRAL 205
IQ LK+ QL EN+ L
Sbjct: 386 KDQLAIQKLKERILQLDLENKTL 408
Score = 39.3 bits (90), Expect = 0.003
Identities = 39/163 (23%), Positives = 78/163 (47%), Gaps = 7/163 (4%)
Query: 64 ESGGSNPTTSDSYGDRASARARREAR----EARLATLTSRVEEDSNRDYKKLYESALTEN 119
E+ S S S GD A + R + +LATLTS + + ++ ++ S L +
Sbjct: 132 EASWSESGVSSSSGDGPFAGGEVDKRLHQLKTQLATLTSSLATVT-QEKSRMEASYLADK 190
Query: 120 QKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEM 179
+K+K L++A + + +++LE + QE+ ++ + L ++ +R + + M E+
Sbjct: 191 KKMKQDLEDASNKAEEERARLEGELKGLQEQIAETKARLITQQHDRAQEQSDHALMLREL 250
Query: 180 KNLHQLKQIQTLKQMNEQLQAENRALTRVVARLSESIESSDTQ 222
+ L L++ +T +Q E E R A +E +E + Q
Sbjct: 251 QKL--LQEERTQRQDLELRLEETREALAGRAYAAEQMEGFELQ 291
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 51.2 bits (121), Expect = 7e-07
Identities = 48/204 (23%), Positives = 86/204 (42%), Gaps = 13/204 (6%)
Query: 4 NENEEADLDEQSSKRLSIRERRRPKERRRGTGINF-WTKDEDETDGSEEVKETWHERLSR 62
++ EE ++E+ R R+ KE +RG ++ DE + E E L
Sbjct: 2177 DDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDE 2236
Query: 63 LESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQKL 122
LE S + + + R E RE R EE+ + + E + +K
Sbjct: 2237 LEKQESLSSEEEEEREEEEEREEEEVREEE----EERKEEEEGEEKQVEKEEEEKKKKKK 2292
Query: 123 KTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKNL 182
+ K +E Q + + K E +++++ E SD E E+ E +LE E++ E + L
Sbjct: 2293 EKKKEEVQEKEEVFEEKEEIMSEEETESLSD-----EEEEEESCSLE---EEVDREKEIL 2344
Query: 183 HQLKQIQTLKQMNEQLQAENRALT 206
+ KQ + +Q + L+ R L+
Sbjct: 2345 KKEKQFKLQEQRRKSLRGRERVLS 2368
Score = 37.0 bits (84), Expect = 0.014
Identities = 35/124 (28%), Positives = 58/124 (46%), Gaps = 17/124 (13%)
Query: 101 EEDSNRDYKKLYESA--LTENQKL----KTKLQEAQLELADIKSKL----EKVAQQKQEK 150
EE+ N++ KL E L E ++ + KL E + +LA + L EK+AQ K++
Sbjct: 1732 EEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKM 1791
Query: 151 TSD-------RSSVLEMEKRERRALERKMSEMEEEMKNLHQLKQIQTLKQMNEQLQAENR 203
+ R ++E + + + ER ++ MEE KN L Q + L Q + L E
Sbjct: 1792 PEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKE 1851
Query: 204 ALTR 207
L +
Sbjct: 1852 KLAQ 1855
Score = 36.6 bits (83), Expect = 0.018
Identities = 49/254 (19%), Positives = 103/254 (40%), Gaps = 37/254 (14%)
Query: 7 EEADLDEQSSKRLSIRER------------RRPKERRRGTGINFWTKDEDETDGSEEV-K 53
EE D+ E+ + ++ E+ R P + + W + ET S + K
Sbjct: 1423 EERDMSEEVEEMATLEEKVVKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWK 1482
Query: 54 ETWHERL----SRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYK 109
E W +RL +L G + + E ++ L+S+ +E +D +
Sbjct: 1483 EEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEE 1542
Query: 110 K--LYESALTENQKLKTKLQEAQLELADI---------KSKLEKVAQQKQEKTSDRSSVL 158
+ L E E ++ + ++ E Q + + +++ EK Q++ K + L
Sbjct: 1543 EVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKL 1602
Query: 159 EMEKRERRALERKMSE----MEEEMKNLHQ-----LKQIQTLKQMNEQLQAENRALTRVV 209
E+R+ ERK+++ + ++ + + Q ++ +TL Q E+L E L +
Sbjct: 1603 AQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKR 1662
Query: 210 ARLSESIESSDTQE 223
+L++ E +E
Sbjct: 1663 KKLAKKWEKVAREE 1676
Score = 33.5 bits (75), Expect = 0.15
Identities = 46/250 (18%), Positives = 100/250 (40%), Gaps = 38/250 (15%)
Query: 1 MDKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERL 60
M++ +E +L+++ K + E+++ E E+ET ++E + E+
Sbjct: 1725 MEELSWKEEELNQEEGKL--VEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKE 1782
Query: 61 SRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYE------- 113
+ P + G + ++ + A+ E+ ++ LY+
Sbjct: 1783 KLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQE 1842
Query: 114 --SALTENQKL----------KTKLQEAQLELADIKSKL---EKVAQQKQEKTSDRSSVL 158
+ E +KL K +L ++ +L +K+KL K+ Q +EK + +
Sbjct: 1843 KKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETV 1902
Query: 159 EMEKRERRALERKMSEME------------EEMKNLHQLKQIQTLKQMNEQLQ--AENRA 204
+K + E+K+ ++E E+MK + +Q K++ +L E +A
Sbjct: 1903 IKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKA 1962
Query: 205 LTRVVARLSE 214
L + RL+E
Sbjct: 1963 LNLEMKRLAE 1972
Score = 31.2 bits (69), Expect = 0.75
Identities = 32/122 (26%), Positives = 51/122 (41%), Gaps = 26/122 (21%)
Query: 113 ESALTENQ----KLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEK------ 162
E LT+ + K K KL E + +L ++ L +KQEK + L +EK
Sbjct: 1892 EEKLTQEKETVIKKKEKLAETEKKLVQVEDSLA----KKQEKLAQEKMKLALEKAMVQGK 1947
Query: 163 ----------RERRALERKMSEMEEEMKNLHQLKQIQTLKQMNEQLQAENRALTRVVARL 212
+E +AL +M + EE L + K +TL + + R +T+V L
Sbjct: 1948 KRLRGELDIAKEEKALNLEMKRLAEEKMRLVEGK--ETLSKGETPETSRQRKMTQVEQEL 2005
Query: 213 SE 214
E
Sbjct: 2006 FE 2007
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 51.2 bits (121), Expect = 7e-07
Identities = 47/193 (24%), Positives = 84/193 (43%), Gaps = 4/193 (2%)
Query: 5 ENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLSRL- 63
E +A EQ + +R +R +ER+R + ++ EE K E L+R
Sbjct: 724 EKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRK 783
Query: 64 -ESGGSNPTTSDSYGDRASARARREAREARLATLTSRV-EEDSNRDYKKLYESALTENQK 121
E + R R+ +E L L R EE+ R ++L E K
Sbjct: 784 QEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAK 843
Query: 122 LKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKN 181
+ +EAQ L + + ++E+ A + + + +R E+E + ++ L R+ + +E ++
Sbjct: 844 WAREEEEAQRRLEENRLRMEEEAARLRHEEEERKR-KELEVQRQKELMRQRQQQQEALRR 902
Query: 182 LHQLKQIQTLKQM 194
L Q +Q Q L QM
Sbjct: 903 LQQQQQQQQLAQM 915
Score = 39.3 bits (90), Expect = 0.003
Identities = 55/248 (22%), Positives = 93/248 (37%), Gaps = 41/248 (16%)
Query: 3 KNENEEADLDEQSSKRLSIR-----ERRRPKE--RRRGTGINFWTKDEDETDGS-EEVKE 54
+ E EE E++ +RL R ERR+ +E R++ W ++E+E EE +
Sbjct: 801 QREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRL 860
Query: 55 TWHERLSRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYES 114
E +RL + R R+ ++ + ++ KL S
Sbjct: 861 RMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSS 920
Query: 115 ALTENQKLKTKLQ-EAQLELADIKS----------------------KLEKVAQQKQEKT 151
+ Q T Q +A L LA+I+ L++ QQ+Q+K
Sbjct: 921 STWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKL 980
Query: 152 SDRSSVLEMEKRERRALERKMSEMEEEMKNLHQLKQIQTLKQMNEQLQAENRALTRVVAR 211
S +V + + LE + E +Q+Q +Q +Q Q NRA +
Sbjct: 981 SGWGNVSKPSGTTKSLLEIQQEE----------ARQMQKQQQQQQQHQQPNRARNNTHSN 1030
Query: 212 LSESIESS 219
L SI +S
Sbjct: 1031 LHTSIGNS 1038
Score = 34.3 bits (77), Expect = 0.089
Identities = 33/155 (21%), Positives = 63/155 (40%), Gaps = 12/155 (7%)
Query: 81 SARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQLELADIKS-- 138
+A+ +E REA + E + ++ E L Q+ + K +E + ELA K
Sbjct: 728 AAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE-ELARRKQEE 786
Query: 139 -----KLEKVAQQKQEKTSDRSSVLE----MEKRERRALERKMSEMEEEMKNLHQLKQIQ 189
+ +++A ++Q + +R E +E+R R ER+ E + K +
Sbjct: 787 ALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAR 846
Query: 190 TLKQMNEQLQAENRALTRVVARLSESIESSDTQEL 224
++ +L+ + ARL E +EL
Sbjct: 847 EEEEAQRRLEENRLRMEEEAARLRHEEEERKRKEL 881
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 51.2 bits (121), Expect = 7e-07
Identities = 47/193 (24%), Positives = 84/193 (43%), Gaps = 4/193 (2%)
Query: 5 ENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLSRL- 63
E +A EQ + +R +R +ER+R + ++ EE K E L+R
Sbjct: 751 EKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRK 810
Query: 64 -ESGGSNPTTSDSYGDRASARARREAREARLATLTSRV-EEDSNRDYKKLYESALTENQK 121
E + R R+ +E L L R EE+ R ++L E K
Sbjct: 811 QEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAK 870
Query: 122 LKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKN 181
+ +EAQ L + + ++E+ A + + + +R E+E + ++ L R+ + +E ++
Sbjct: 871 WAREEEEAQRRLEENRLRMEEEAARLRHEEEERKR-KELEVQRQKELMRQRQQQQEALRR 929
Query: 182 LHQLKQIQTLKQM 194
L Q +Q Q L QM
Sbjct: 930 LQQQQQQQQLAQM 942
Score = 39.3 bits (90), Expect = 0.003
Identities = 55/248 (22%), Positives = 93/248 (37%), Gaps = 41/248 (16%)
Query: 3 KNENEEADLDEQSSKRLSIR-----ERRRPKE--RRRGTGINFWTKDEDETDGS-EEVKE 54
+ E EE E++ +RL R ERR+ +E R++ W ++E+E EE +
Sbjct: 828 QREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRL 887
Query: 55 TWHERLSRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYES 114
E +RL + R R+ ++ + ++ KL S
Sbjct: 888 RMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSS 947
Query: 115 ALTENQKLKTKLQ-EAQLELADIKS----------------------KLEKVAQQKQEKT 151
+ Q T Q +A L LA+I+ L++ QQ+Q+K
Sbjct: 948 STWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKL 1007
Query: 152 SDRSSVLEMEKRERRALERKMSEMEEEMKNLHQLKQIQTLKQMNEQLQAENRALTRVVAR 211
S +V + + LE + E +Q+Q +Q +Q Q NRA +
Sbjct: 1008 SGWGNVSKPSGTTKSLLEIQQEE----------ARQMQKQQQQQQQHQQPNRARNNTHSN 1057
Query: 212 LSESIESS 219
L SI +S
Sbjct: 1058 LHTSIGNS 1065
Score = 34.3 bits (77), Expect = 0.089
Identities = 33/155 (21%), Positives = 63/155 (40%), Gaps = 12/155 (7%)
Query: 81 SARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQLELADIKS-- 138
+A+ +E REA + E + ++ E L Q+ + K +E + ELA K
Sbjct: 755 AAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE-ELARRKQEE 813
Query: 139 -----KLEKVAQQKQEKTSDRSSVLE----MEKRERRALERKMSEMEEEMKNLHQLKQIQ 189
+ +++A ++Q + +R E +E+R R ER+ E + K +
Sbjct: 814 ALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAR 873
Query: 190 TLKQMNEQLQAENRALTRVVARLSESIESSDTQEL 224
++ +L+ + ARL E +EL
Sbjct: 874 EEEEAQRRLEENRLRMEEEAARLRHEEEERKRKEL 908
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 51.2 bits (121), Expect = 7e-07
Identities = 47/193 (24%), Positives = 84/193 (43%), Gaps = 4/193 (2%)
Query: 5 ENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLSRL- 63
E +A EQ + +R +R +ER+R + ++ EE K E L+R
Sbjct: 730 EKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRK 789
Query: 64 -ESGGSNPTTSDSYGDRASARARREAREARLATLTSRV-EEDSNRDYKKLYESALTENQK 121
E + R R+ +E L L R EE+ R ++L E K
Sbjct: 790 QEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAK 849
Query: 122 LKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKN 181
+ +EAQ L + + ++E+ A + + + +R E+E + ++ L R+ + +E ++
Sbjct: 850 WAREEEEAQRRLEENRLRMEEEAARLRHEEEERKR-KELEVQRQKELMRQRQQQQEALRR 908
Query: 182 LHQLKQIQTLKQM 194
L Q +Q Q L QM
Sbjct: 909 LQQQQQQQQLAQM 921
Score = 39.3 bits (90), Expect = 0.003
Identities = 55/248 (22%), Positives = 93/248 (37%), Gaps = 41/248 (16%)
Query: 3 KNENEEADLDEQSSKRLSIR-----ERRRPKE--RRRGTGINFWTKDEDETDGS-EEVKE 54
+ E EE E++ +RL R ERR+ +E R++ W ++E+E EE +
Sbjct: 807 QREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRL 866
Query: 55 TWHERLSRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYES 114
E +RL + R R+ ++ + ++ KL S
Sbjct: 867 RMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSS 926
Query: 115 ALTENQKLKTKLQ-EAQLELADIKS----------------------KLEKVAQQKQEKT 151
+ Q T Q +A L LA+I+ L++ QQ+Q+K
Sbjct: 927 STWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKL 986
Query: 152 SDRSSVLEMEKRERRALERKMSEMEEEMKNLHQLKQIQTLKQMNEQLQAENRALTRVVAR 211
S +V + + LE + E +Q+Q +Q +Q Q NRA +
Sbjct: 987 SGWGNVSKPSGTTKSLLEIQQEE----------ARQMQKQQQQQQQHQQPNRARNNTHSN 1036
Query: 212 LSESIESS 219
L SI +S
Sbjct: 1037 LHTSIGNS 1044
Score = 34.3 bits (77), Expect = 0.089
Identities = 33/155 (21%), Positives = 63/155 (40%), Gaps = 12/155 (7%)
Query: 81 SARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQLELADIKS-- 138
+A+ +E REA + E + ++ E L Q+ + K +E + ELA K
Sbjct: 734 AAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE-ELARRKQEE 792
Query: 139 -----KLEKVAQQKQEKTSDRSSVLE----MEKRERRALERKMSEMEEEMKNLHQLKQIQ 189
+ +++A ++Q + +R E +E+R R ER+ E + K +
Sbjct: 793 ALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAR 852
Query: 190 TLKQMNEQLQAENRALTRVVARLSESIESSDTQEL 224
++ +L+ + ARL E +EL
Sbjct: 853 EEEEAQRRLEENRLRMEEEAARLRHEEEERKRKEL 887
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 51.2 bits (121), Expect = 7e-07
Identities = 47/193 (24%), Positives = 84/193 (43%), Gaps = 4/193 (2%)
Query: 5 ENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLSRL- 63
E +A EQ + +R +R +ER+R + ++ EE K E L+R
Sbjct: 730 EKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRK 789
Query: 64 -ESGGSNPTTSDSYGDRASARARREAREARLATLTSRV-EEDSNRDYKKLYESALTENQK 121
E + R R+ +E L L R EE+ R ++L E K
Sbjct: 790 QEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAK 849
Query: 122 LKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKN 181
+ +EAQ L + + ++E+ A + + + +R E+E + ++ L R+ + +E ++
Sbjct: 850 WAREEEEAQRRLEENRLRMEEEAARLRHEEEERKR-KELEVQRQKELMRQRQQQQEALRR 908
Query: 182 LHQLKQIQTLKQM 194
L Q +Q Q L QM
Sbjct: 909 LQQQQQQQQLAQM 921
Score = 39.3 bits (90), Expect = 0.003
Identities = 55/248 (22%), Positives = 93/248 (37%), Gaps = 41/248 (16%)
Query: 3 KNENEEADLDEQSSKRLSIR-----ERRRPKE--RRRGTGINFWTKDEDETDGS-EEVKE 54
+ E EE E++ +RL R ERR+ +E R++ W ++E+E EE +
Sbjct: 807 QREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRL 866
Query: 55 TWHERLSRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYES 114
E +RL + R R+ ++ + ++ KL S
Sbjct: 867 RMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSS 926
Query: 115 ALTENQKLKTKLQ-EAQLELADIKS----------------------KLEKVAQQKQEKT 151
+ Q T Q +A L LA+I+ L++ QQ+Q+K
Sbjct: 927 STWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKL 986
Query: 152 SDRSSVLEMEKRERRALERKMSEMEEEMKNLHQLKQIQTLKQMNEQLQAENRALTRVVAR 211
S +V + + LE + E +Q+Q +Q +Q Q NRA +
Sbjct: 987 SGWGNVSKPSGTTKSLLEIQQEE----------ARQMQKQQQQQQQHQQPNRARNNTHSN 1036
Query: 212 LSESIESS 219
L SI +S
Sbjct: 1037 LHTSIGNS 1044
Score = 34.3 bits (77), Expect = 0.089
Identities = 33/155 (21%), Positives = 63/155 (40%), Gaps = 12/155 (7%)
Query: 81 SARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQLELADIKS-- 138
+A+ +E REA + E + ++ E L Q+ + K +E + ELA K
Sbjct: 734 AAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE-ELARRKQEE 792
Query: 139 -----KLEKVAQQKQEKTSDRSSVLE----MEKRERRALERKMSEMEEEMKNLHQLKQIQ 189
+ +++A ++Q + +R E +E+R R ER+ E + K +
Sbjct: 793 ALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAR 852
Query: 190 TLKQMNEQLQAENRALTRVVARLSESIESSDTQEL 224
++ +L+ + ARL E +EL
Sbjct: 853 EEEEAQRRLEENRLRMEEEAARLRHEEEERKRKEL 887
>gi|15149463 caldesmon 1 isoform 4 [Homo sapiens]
Length = 558
Score = 51.2 bits (121), Expect = 7e-07
Identities = 51/189 (26%), Positives = 88/189 (46%), Gaps = 23/189 (12%)
Query: 2 DKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLS 61
+K + ++ ++ K I++ + PKE + +F + + T+ + E +L
Sbjct: 214 EKLQEDKPTFKKEEIKDEKIKKDKEPKEEVK----SFMDRKKGFTEVKSQNGEFMTHKLK 269
Query: 62 RLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQK 121
E+ S P G RAS + EA A R+EE R E+ E +K
Sbjct: 270 HTENTFSRP------GGRASVDTK-EAEGAPQVEAGKRLEELRRRRG----ETESEEFEK 318
Query: 122 LKTKLQEAQLELADIKSK-------LEKVAQQKQEKTSDRSSVLEMEKRE-RRALERKMS 173
LK K QEA LEL ++K K LE+ Q+++++ +DR E EKR + +ER+ +
Sbjct: 319 LKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRA 378
Query: 174 EMEEEMKNL 182
E E+ + +
Sbjct: 379 EAAEKRQKM 387
Score = 32.0 bits (71), Expect = 0.44
Identities = 49/249 (19%), Positives = 94/249 (37%), Gaps = 41/249 (16%)
Query: 2 DKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLS 61
D ENE + +E+S R E + + N W D + +E KE E
Sbjct: 134 DTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDW---RDAEENKKEDKEKEEEEEE 190
Query: 62 RLESGGSNPTTSDSYGDRASAR-----------ARREAREARLATLTSRVEE-DSNRDYK 109
+ + G + G + A+ + E ++ ++ EE S D K
Sbjct: 191 KPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRK 250
Query: 110 KLYESALTENQKLKT-KLQEAQLELA-------------------DIKSKLEKVAQQKQE 149
K + ++N + T KL+ + + + +LE++ +++ E
Sbjct: 251 KGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGE 310
Query: 150 KTSDRSSVLEMEKRERR-ALERKMSEMEEEMKNLHQLKQIQTLKQMNEQLQAENRALTRV 208
S+ L+ +++E LE + EE K L + +Q + ++ + +L+ E
Sbjct: 311 TESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEK---- 366
Query: 209 VARLSESIE 217
RL E IE
Sbjct: 367 -RRLKEEIE 374
Score = 30.8 bits (68), Expect = 0.98
Identities = 39/216 (18%), Positives = 82/216 (37%), Gaps = 16/216 (7%)
Query: 3 KNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLSR 62
+ + EE L + + + + P E + T N + +DE E + R R
Sbjct: 45 RQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKR 104
Query: 63 LESGGS-----NPTTSDSYGDRASARARREAREARLATLTSRVE-----------EDSNR 106
L+ +PT +D+ S R + + E + E E +
Sbjct: 105 LQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTK 164
Query: 107 DYKKLYESALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERR 166
Y+K EN+K + +E + E S E ++K K + L+ +K +
Sbjct: 165 SYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFK 224
Query: 167 ALERKMSEMEEEMKNLHQLKQIQTLKQMNEQLQAEN 202
E K +++++ + ++K K+ +++++N
Sbjct: 225 KEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQN 260
>gi|15149467 caldesmon 1 isoform 3 [Homo sapiens]
Length = 564
Score = 51.2 bits (121), Expect = 7e-07
Identities = 51/189 (26%), Positives = 88/189 (46%), Gaps = 23/189 (12%)
Query: 2 DKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLS 61
+K + ++ ++ K I++ + PKE + +F + + T+ + E +L
Sbjct: 220 EKLQEDKPTFKKEEIKDEKIKKDKEPKEEVK----SFMDRKKGFTEVKSQNGEFMTHKLK 275
Query: 62 RLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQK 121
E+ S P G RAS + EA A R+EE R E+ E +K
Sbjct: 276 HTENTFSRP------GGRASVDTK-EAEGAPQVEAGKRLEELRRRRG----ETESEEFEK 324
Query: 122 LKTKLQEAQLELADIKSK-------LEKVAQQKQEKTSDRSSVLEMEKRE-RRALERKMS 173
LK K QEA LEL ++K K LE+ Q+++++ +DR E EKR + +ER+ +
Sbjct: 325 LKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRA 384
Query: 174 EMEEEMKNL 182
E E+ + +
Sbjct: 385 EAAEKRQKM 393
Score = 32.0 bits (71), Expect = 0.44
Identities = 49/249 (19%), Positives = 94/249 (37%), Gaps = 41/249 (16%)
Query: 2 DKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLS 61
D ENE + +E+S R E + + N W D + +E KE E
Sbjct: 140 DTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDW---RDAEENKKEDKEKEEEEEE 196
Query: 62 RLESGGSNPTTSDSYGDRASAR-----------ARREAREARLATLTSRVEE-DSNRDYK 109
+ + G + G + A+ + E ++ ++ EE S D K
Sbjct: 197 KPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRK 256
Query: 110 KLYESALTENQKLKT-KLQEAQLELA-------------------DIKSKLEKVAQQKQE 149
K + ++N + T KL+ + + + +LE++ +++ E
Sbjct: 257 KGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGE 316
Query: 150 KTSDRSSVLEMEKRERR-ALERKMSEMEEEMKNLHQLKQIQTLKQMNEQLQAENRALTRV 208
S+ L+ +++E LE + EE K L + +Q + ++ + +L+ E
Sbjct: 317 TESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEK---- 372
Query: 209 VARLSESIE 217
RL E IE
Sbjct: 373 -RRLKEEIE 380
Score = 30.8 bits (68), Expect = 0.98
Identities = 39/216 (18%), Positives = 82/216 (37%), Gaps = 16/216 (7%)
Query: 3 KNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLSR 62
+ + EE L + + + + P E + T N + +DE E + R R
Sbjct: 51 RQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKR 110
Query: 63 LESGGS-----NPTTSDSYGDRASARARREAREARLATLTSRVE-----------EDSNR 106
L+ +PT +D+ S R + + E + E E +
Sbjct: 111 LQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTK 170
Query: 107 DYKKLYESALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERR 166
Y+K EN+K + +E + E S E ++K K + L+ +K +
Sbjct: 171 SYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFK 230
Query: 167 ALERKMSEMEEEMKNLHQLKQIQTLKQMNEQLQAEN 202
E K +++++ + ++K K+ +++++N
Sbjct: 231 KEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQN 266
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 50.4 bits (119), Expect = 1e-06
Identities = 50/224 (22%), Positives = 101/224 (45%), Gaps = 27/224 (12%)
Query: 7 EEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDET----DGSEEVKETWHERLSR 62
E D K S R K+ + G + W + +E+ D S++ + L +
Sbjct: 1436 ELGDALSDLGKVRSAAARLDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELLK 1495
Query: 63 LESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQKL 122
L++ T +S + + R + + ++ LT++V E + LTE +K+
Sbjct: 1496 LKN-----TYEESIVGQETLRRENKNLQEEISNLTNQVREGTKN---------LTEMEKV 1541
Query: 123 KTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRA-LERKMSEMEEEMKN 181
K ++E + E+ + E ++ + K ++E E +A LERK+SE +EE++N
Sbjct: 1542 KKLIEEEKTEVQVTLEETEGALERNESKILH----FQLELLEAKAELERKLSEKDEEIEN 1597
Query: 182 LHQLKQIQTLKQMNEQLQAENRA---LTRVVARLSESIESSDTQ 222
+ KQ T+ + L +E ++ +TR+ ++ E + + Q
Sbjct: 1598 FRR-KQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQ 1640
Score = 36.2 bits (82), Expect = 0.023
Identities = 24/110 (21%), Positives = 54/110 (49%), Gaps = 19/110 (17%)
Query: 113 ESALTENQKLKTKLQEAQLELADIKSKLE----------KVAQQKQEKTSDRSSVLEMEK 162
E+ + + L +L++ +LEL+ + SK+E K ++ Q + D LE E+
Sbjct: 1079 ENLESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAER 1138
Query: 163 RERRALERKMSEMEEEMKNLHQ---------LKQIQTLKQMNEQLQAENR 203
R +ER+ +++ +++ +L++ L Q++ K+ + Q +R
Sbjct: 1139 TTRAKMERERADLTQDLADLNERLEEVGGSSLAQLEITKKQETKFQKLHR 1188
Score = 34.3 bits (77), Expect = 0.089
Identities = 33/154 (21%), Positives = 69/154 (44%), Gaps = 35/154 (22%)
Query: 89 REARLATLTSRVEEDSN----------------RDYKKLYESALTENQKLKTKLQEAQLE 132
+E L+ + S+VE + +D K+ E+ T K++ + + +
Sbjct: 1095 KELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQD 1154
Query: 133 LADIKSKLEKVAQQ--------KQEKTSDRSSVLEMEKRE----------RRALERKMSE 174
LAD+ +LE+V K+++T + +ME+ ++ ++E
Sbjct: 1155 LADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSLAE 1214
Query: 175 MEEEMKNLHQLKQIQTLKQMNEQLQAENRALTRV 208
+E +++NL Q+KQ + + QL+ ++ LTRV
Sbjct: 1215 LEGQVENLQQVKQKLEKDKSDLQLEVDD-LLTRV 1247
Score = 31.2 bits (69), Expect = 0.75
Identities = 23/95 (24%), Positives = 42/95 (44%), Gaps = 23/95 (24%)
Query: 90 EARLATLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQE 149
EAR+ L+ RVEE+ +E EL KLE + ++
Sbjct: 928 EARVKELSERVEEE-----------------------EEINSELTARGRKLEDECFELKK 964
Query: 150 KTSDRSSVLEMEKRERRALERKMSEMEEEMKNLHQ 184
+ D ++L ++E+R E K+ + EE++ L++
Sbjct: 965 EIDDLETMLVKSEKEKRTTEHKVKNLTEEVEFLNE 999
Score = 31.2 bits (69), Expect = 0.75
Identities = 37/186 (19%), Positives = 77/186 (41%), Gaps = 17/186 (9%)
Query: 43 EDETDGSEEVKETWHERLSRLESGGSNPTTSDS-YGDRASARARREAREARLATLTSRVE 101
+D D +E ++E L++LE T + D A E A L +
Sbjct: 1153 QDLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSASL----KKRH 1208
Query: 102 EDSNRDYKKLYESALTENQKLKTKLQEAQLELADIKSKLEKVAQQK----------QEKT 151
DS + + E+ QKL+ + QLE+ D+ +++E++ + K +E+
Sbjct: 1209 ADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERL 1268
Query: 152 SDRSSVLEMEKRERRALERKMSEMEEEMKNLHQLKQIQTLKQMNEQLQAENRALTRVVAR 211
+ ++ L+ + L + +++ E L++++ + + QL E TR +
Sbjct: 1269 HEATAKLDKVTQLANDLAAQKTKLWSESGEF--LRRLEEKEALINQLSREKSNFTRQIED 1326
Query: 212 LSESIE 217
L +E
Sbjct: 1327 LRGQLE 1332
Score = 30.0 bits (66), Expect = 1.7
Identities = 33/140 (23%), Positives = 59/140 (42%), Gaps = 7/140 (5%)
Query: 84 ARREAREARLATLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQLELADIKSKLEKV 143
AR E L +++ K E TE+ K+K +E + DI SKL +
Sbjct: 950 ARGRKLEDECFELKKEIDDLETMLVKSEKEKRTTEH-KVKNLTEEVEFLNEDI-SKLNRA 1007
Query: 144 AQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKNLHQLKQIQTLKQMNEQLQAENR 203
A+ QE L ME+ + +L + ++E+++ L + + +MN + R
Sbjct: 1008 AKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQVDELEGALEQERKARMNCE-----R 1062
Query: 204 ALTRVVARLSESIESSDTQE 223
L ++ L + ES + E
Sbjct: 1063 ELHKLEGNLKLNRESMENLE 1082
Score = 29.3 bits (64), Expect = 2.8
Identities = 34/179 (18%), Positives = 78/179 (43%), Gaps = 14/179 (7%)
Query: 43 EDETDGSEEVKETWHERLSRLESGGSNPTTSDSYGDRASARARREAR--EARLATLTSRV 100
E + + ++VK+ + S L+ + T RA A A + E RL T+++
Sbjct: 1216 EGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKL 1275
Query: 101 EE------DSNRDYKKLYESALTENQKLKTK---LQEAQLELADIKSKLEKVAQQKQEKT 151
++ D KL+ + ++L+ K + + E ++ ++E + Q +++T
Sbjct: 1276 DKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKET 1335
Query: 152 SDRSSV---LEMEKRERRALERKMSEMEEEMKNLHQLKQIQTLKQMNEQLQAENRALTR 207
+S++ L+ +R+ L + E +E LH+ + + +++ EN + R
Sbjct: 1336 KSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQR 1394
Score = 28.9 bits (63), Expect = 3.7
Identities = 26/115 (22%), Positives = 54/115 (46%), Gaps = 12/115 (10%)
Query: 111 LYESALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRER----R 166
LYE L E K+ + +LA K+KL + + + ++ +++ RE+ R
Sbjct: 1263 LYEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTR 1322
Query: 167 ALERKMSEMEEEMKN----LHQLKQIQ----TLKQMNEQLQAENRALTRVVARLS 213
+E ++E+E K+ H L++ Q L++ E+ Q L R +++++
Sbjct: 1323 QIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVN 1377
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 50.1 bits (118), Expect = 2e-06
Identities = 46/232 (19%), Positives = 102/232 (43%), Gaps = 17/232 (7%)
Query: 1 MDKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERL 60
+++ +E+ + EQ KR E+ R +E+R+ W ++E + E+++E +
Sbjct: 382 LEEKMHEQEKIREQEEKRQE-EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMW 440
Query: 61 SRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQ 120
+ E + R+E E R +E+ R +K++E Q
Sbjct: 441 RQEEKIHEQEKIREE-------EKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQ 493
Query: 121 KLKTKLQEAQLELAD--IKSKLEKVAQQKQEKTSDRSSVLEMEKRER------RALERKM 172
+ K QE ++ + I+ + EK+ +Q+++ + E E++ R + E KM
Sbjct: 494 EEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKM 553
Query: 173 SEMEEEMKNLHQL-KQIQTLKQMNEQLQAENRALTRVVARLSESIESSDTQE 223
E EE+M+ ++ +Q + +++ E+++ + + ++ E E QE
Sbjct: 554 GEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQE 605
Score = 43.1 bits (100), Expect = 2e-04
Identities = 45/227 (19%), Positives = 92/227 (40%), Gaps = 16/227 (7%)
Query: 2 DKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLS 61
+K + E + EQ K E+ R +E + + E++ EE+ E++
Sbjct: 307 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 366
Query: 62 RLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQK 121
RLE RE E R +E+ ++ +K+ E + Q+
Sbjct: 367 RLEEMMWE-----------KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 415
Query: 122 LKTKLQEAQLELADIK-SKLEKVAQQKQEKTSDRSSVLEMEKRERR----ALERKMSEME 176
K QE ++ + K + EK +++EK ++ + E EKR+ + E K+ E E
Sbjct: 416 AKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQE 475
Query: 177 EEMKNLHQLKQIQTLKQMNEQLQAENRALTRVVARLSESIESSDTQE 223
E + ++ + + +++ E++ + + ++ E E QE
Sbjct: 476 EIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQE 522
Score = 42.0 bits (97), Expect = 4e-04
Identities = 35/180 (19%), Positives = 80/180 (44%), Gaps = 13/180 (7%)
Query: 22 RERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLSRLESGGSNPTTSDSYGDRAS 81
+E+ +E+ R W ++E D E+++E E++ R E + ++
Sbjct: 481 KEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQ-EEKMWRQE---------EKIREQEE 530
Query: 82 ARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQL--ELADIKSK 139
+E + + EE +K+ E Q+ K + QE ++ + I+ +
Sbjct: 531 KIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQ 590
Query: 140 LEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKNLHQLKQIQTLKQMNEQLQ 199
EK+ +Q +EK ++ +++ ++ + E KM E EE+M+ + + Q K ++++
Sbjct: 591 EEKIWEQ-EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVR 649
Score = 37.4 bits (85), Expect = 0.010
Identities = 31/127 (24%), Positives = 63/127 (49%), Gaps = 4/127 (3%)
Query: 81 SARARREAREARLAT-LTSRVEEDSNRDYKKLYE-SALTENQKLKTKLQEAQLELADIKS 138
SA+ + + E L L + EE R +K+ E + Q+ K + QE ++ + K
Sbjct: 278 SAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKM 337
Query: 139 KLEKVAQQKQEKTSDRSSVLEMEKRER-RALERKMSEMEEEMKNLHQ-LKQIQTLKQMNE 196
+ ++ ++E+ R + EK E+ R LE M E EE+++ L + + + + +++ E
Sbjct: 338 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEE 397
Query: 197 QLQAENR 203
+ Q E +
Sbjct: 398 KRQEEEK 404
Score = 36.6 bits (83), Expect = 0.018
Identities = 37/219 (16%), Positives = 90/219 (41%), Gaps = 31/219 (14%)
Query: 2 DKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDED--------ETDGSEEVK 53
+K + +EA + Q K E+ R +E++ W ++E E + +E +
Sbjct: 409 EKRQEQEAKMWRQEEKIREQEEKIREQEKK------MWRQEEKIHEQEKIREEEKRQEQE 462
Query: 54 ETWHERLSRLESGGSNPTTSDSYGDRASARARREA---REARLATLTSRVEEDSNRDYK- 109
E W + ++ + ++ R + E +E ++ ++ E + ++
Sbjct: 463 EMWRQE-EKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQ 521
Query: 110 -----------KLYESALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVL 158
+ E + E +++ + +E E + + EK+ +Q +EK ++ +
Sbjct: 522 EEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQ-EEKIREQEEKI 580
Query: 159 EMEKRERRALERKMSEMEEEMKNLHQLKQIQTLKQMNEQ 197
+K + R E K+ E EE+++ ++ Q Q K ++
Sbjct: 581 REQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQE 619
Score = 30.4 bits (67), Expect = 1.3
Identities = 28/125 (22%), Positives = 59/125 (47%), Gaps = 18/125 (14%)
Query: 114 SALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSD------RSSVLEMEKRERRA 167
S L ++ K +L++A +A K K ++ ++ ++ R+++ + E +E+ A
Sbjct: 165 SRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNA 224
Query: 168 --------LERKMSEMEEEMKNLHQLKQIQTLKQMNEQLQAE----NRALTRVVARLSES 215
+E + SE++ +K L + + L +QLQAE + L V A+L
Sbjct: 225 KLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQ 284
Query: 216 IESSD 220
+E ++
Sbjct: 285 VEENE 289
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 50.1 bits (118), Expect = 2e-06
Identities = 46/183 (25%), Positives = 76/183 (41%), Gaps = 24/183 (13%)
Query: 24 RRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLSRLESGGSNPTTSDSYGDRASAR 83
R PKE+ R N K+E E ++V+E RL + +
Sbjct: 527 RMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEV-------------------K 567
Query: 84 ARREAREARLATLTSRVEEDSNRDYKKLYESAL-----TENQKLKTKLQEAQLELADIKS 138
+RE R ++ RVE+ K++ + TE K + +E + A K
Sbjct: 568 LKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKK 627
Query: 139 KLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKNLHQLKQIQTLKQMNEQL 198
E A++KQE+ + R L+ E+ ERR E + EEE + L + + + L + EQ
Sbjct: 628 MEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQE 687
Query: 199 QAE 201
+ E
Sbjct: 688 RRE 690
Score = 45.1 bits (105), Expect = 5e-05
Identities = 50/203 (24%), Positives = 86/203 (42%), Gaps = 24/203 (11%)
Query: 7 EEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLSRLESG 66
EE L + R ++ R R ++ + K + +E+ KE RL
Sbjct: 564 EEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKE------ERLAEE 617
Query: 67 GSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQKLKTKL 126
+ + + AR ++E RL L +E+ R +++L QK K +
Sbjct: 618 KAKKKAAAKKMEEVEARRKQEEEARRLRWLQ---QEEEERRHQELL-------QKKKEEE 667
Query: 127 QEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRE--RRALERKMSEMEE--EMKNL 182
QE + A+ K E+ Q+++E+ E E+RE RR ER+++E E E + L
Sbjct: 668 QERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERL 727
Query: 183 HQLKQIQ----TLKQMNEQLQAE 201
+++Q L+ EQLQ E
Sbjct: 728 QAERELQEREKALRLQKEQLQRE 750
Score = 38.5 bits (88), Expect = 0.005
Identities = 46/225 (20%), Positives = 98/225 (43%), Gaps = 30/225 (13%)
Query: 3 KNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLSR 62
+N D E+ +RL R+ E+ R + +ED+ EEVK ERL +
Sbjct: 522 RNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKV-----EEDKRRRLEEVKLKREERLRK 576
Query: 63 LESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQKL 122
+ + + + E + A++ T + +E+ + K ++A + +++
Sbjct: 577 VLQARERVEQM-----KEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEV 631
Query: 123 KTKLQEAQ-------LELADIKSKLEKVAQQKQEKTSDR-------SSVLEMEKRERRAL 168
+ + ++ + L+ + + + +++ Q+K+E+ +R + E ++ERR
Sbjct: 632 EARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQ 691
Query: 169 ERKMSEMEE----EMKNLHQLKQI--QTLKQMNEQLQAENRALTR 207
ER+ E E E + Q +Q+ Q ++ E+LQAE R
Sbjct: 692 ERREQERREQERREQERREQERQLAEQERRREQERLQAERELQER 736
Score = 37.7 bits (86), Expect = 0.008
Identities = 41/222 (18%), Positives = 93/222 (41%), Gaps = 31/222 (13%)
Query: 5 ENEEADLDEQSSK----RLSIRERRRPKERRRGTGINFWTKDEDETDG----SEEVKETW 56
E + A +DE++ K RL+ + ++ ++ + K E+E +E +E
Sbjct: 596 EQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERR 655
Query: 57 HERLSRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESAL 116
H+ L + + + R R+ A RLA + + R ++ E
Sbjct: 656 HQELLQKKK------------EEEQERLRKAAEAKRLAE-----QREQERREQERREQER 698
Query: 117 TENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEME 176
E ++ + + +E + +LA+ + + E+ Q + + +R L ++K E+ E+E
Sbjct: 699 REQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQK------EQLQRELE 752
Query: 177 EEMKNLHQLKQIQTLKQMNEQLQAENRALTRVVARLSESIES 218
E+ K Q + + Q ++ +A+ A ++ ++S
Sbjct: 753 EKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQS 794
Score = 34.3 bits (77), Expect = 0.089
Identities = 32/126 (25%), Positives = 61/126 (48%), Gaps = 11/126 (8%)
Query: 109 KKLYESALTENQKLKTKLQEAQ---LELADIKSKLEKVAQQKQEKTSDR---SSVLEMEK 162
+ + +S + N L+ +E + LE K + E++ +QK E+ R L+ E+
Sbjct: 513 RSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREE 572
Query: 163 RERRALE--RKMSEMEEEMKNLHQLKQIQ---TLKQMNEQLQAENRALTRVVARLSESIE 217
R R+ L+ ++ +M+EE K + K Q ++ E+ AE +A + A+ E +E
Sbjct: 573 RLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVE 632
Query: 218 SSDTQE 223
+ QE
Sbjct: 633 ARRKQE 638
>gi|157042792 coiled-coil domain containing 64B [Homo sapiens]
Length = 508
Score = 49.7 bits (117), Expect = 2e-06
Identities = 55/245 (22%), Positives = 104/245 (42%), Gaps = 34/245 (13%)
Query: 1 MDKNENEEADLDEQSSKRLSIRERRRPK--ERRRGTGINF--WTKDEDETDGSEEVKETW 56
+++NE L+ S++ L ER + + E RRG W E +G E
Sbjct: 72 LERNEELRRQLETLSAQHLEREERLQQENHELRRGLAARGAEWEARAVELEGDVEAL--- 128
Query: 57 HERLSRLESGGSNPTTSDSYGDRASARARREAREARLA---TLTSRVEEDSNRDYKKL-- 111
R + G DS +RA A + + RL+ S+ E++ R+ L
Sbjct: 129 -----RAQLGEQRSEQQDSGRERARALSELSEQNLRLSQQLAQASQTEQELQRELDALRG 183
Query: 112 ---------------YESALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSS 156
ES ENQ L+++ Q+ + ++ ++ ++EK + + + T +
Sbjct: 184 QCQAQALAGAELRTRLESLQGENQMLQSRRQDLEAQIRGLREEVEK-GEGRLQTTHEELL 242
Query: 157 VLEMEKRERR-ALERKMSEMEEEMKNLHQLKQIQTLKQMNEQLQAENRALTRVVARLSES 215
+L E+RE LER SE E + L +L++ + + +LQ + + + + L+ S
Sbjct: 243 LLRRERREHSLELERARSEAGEALSALRRLQRRVSELEEESRLQDADVSAASLQSELAHS 302
Query: 216 IESSD 220
++ D
Sbjct: 303 LDDGD 307
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 49.3 bits (116), Expect = 3e-06
Identities = 45/227 (19%), Positives = 101/227 (44%), Gaps = 10/227 (4%)
Query: 2 DKNENEEADLDEQSSKRLSIRERRRPKERR-RGTGINFWTKDEDETDGSEEVKETWHERL 60
+K +E + EQ K E+ R +E + R W ++E + E+++E E
Sbjct: 332 EKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMW 391
Query: 61 SRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQ 120
+ E R + R + + R +E+ R+ +++ + + +
Sbjct: 392 RQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLR 451
Query: 121 KLKTKLQEAQLELADIKSKL---EKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEE 177
+++ K+QE + ++ + + K+ E+ Q+++EKT + +L+ E++ E KM EE
Sbjct: 452 EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQ-EEKMWRQEE 510
Query: 178 EMKNLHQLKQIQTLKQMNEQLQAENRALTRVVARLSESIESSDTQEL 224
+M +Q + +++ E++Q + + RL + E QE+
Sbjct: 511 KM-----WEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEV 552
Score = 35.8 bits (81), Expect = 0.030
Identities = 38/188 (20%), Positives = 77/188 (40%), Gaps = 16/188 (8%)
Query: 7 EEADLDEQSSKRLSIRERRRPKERRRGTGIN-----FWTKDEDETDGSEEVKETWHERLS 61
+E + EQ KR R+ K R + I W + E++ EE+ + E+L
Sbjct: 393 QEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMW-RQEEKIRELEEMMQDQEEKLR 451
Query: 62 RLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKL-YESALTENQ 120
+E + + +E + R EE + R K L E + E +
Sbjct: 452 EVE---------EKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQE 502
Query: 121 KLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMK 180
+ + +E E + + E+ Q+++EK ++ L ++ + + E ++ E+EE +
Sbjct: 503 EKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLG 562
Query: 181 NLHQLKQI 188
L Q ++
Sbjct: 563 KLGQKAEL 570
Score = 31.2 bits (69), Expect = 0.75
Identities = 38/179 (21%), Positives = 71/179 (39%), Gaps = 51/179 (28%)
Query: 95 TLTSRVEEDSNRDYK---KLYESALTENQ----KLKTKLQEAQL---------------- 131
T+T ++ N + + +L ES +E Q LK KL+ AQL
Sbjct: 210 TITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGK 269
Query: 132 ELADIKSKL-------------------------EKVAQQKQEKTSDRSSVLEMEKRERR 166
EL + +KL EK+ +Q+++ + E E++ R
Sbjct: 270 ELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWR 329
Query: 167 ALERKMSEMEEEMKNLH--QLKQIQTLKQMNEQLQAENRALTRVVARLSESIESSDTQE 223
E KM E EE+++ +Q + +++ E+++ + + R ++ E E QE
Sbjct: 330 Q-EEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE 387
Score = 30.8 bits (68), Expect = 0.98
Identities = 27/147 (18%), Positives = 67/147 (45%), Gaps = 22/147 (14%)
Query: 99 RVEEDSNRDYKKLYESALT---ENQKL---KTKLQEAQLELADIKSKL---EKVAQQKQE 149
R EE +K+ E L + +K+ + K+ E + ++ + + K+ E+ ++++E
Sbjct: 301 RQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEE 360
Query: 150 KTSDRSSVLEMEKRERRALERKMSEMEEEM-------------KNLHQLKQIQTLKQMNE 196
K ++ + ++ + R + K+ E EEEM + +Q + +++ +E
Sbjct: 361 KIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDE 420
Query: 197 QLQAENRALTRVVARLSESIESSDTQE 223
+++ + + R ++ E E QE
Sbjct: 421 KIREQEEEMWRQEEKIRELEEMMQDQE 447
Score = 30.0 bits (66), Expect = 1.7
Identities = 48/229 (20%), Positives = 91/229 (39%), Gaps = 37/229 (16%)
Query: 8 EADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDED--ETDGSEEVKETWHERLSRL-- 63
E + ++ +LS E +RRGT W +D+D E++ S++ KE+ L
Sbjct: 55 EKSIADEKFFQLSEMEAYLENRKRRGT--KRWDEDDDLEESEDSKQCKESLKRVTFTLPD 112
Query: 64 ----ESGGSNPTTSDSYGDRASARARREAREARLATLTSRVE-----------EDSNRDY 108
E G + +S ++S + R+E + T RV R
Sbjct: 113 DEAIEDAGVSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPE 172
Query: 109 KKLYESAL---------TENQKLKTKLQEAQLEL-------ADIKSKLEKVAQQKQEKTS 152
L E L T +KL + LEL ++K K ++ ++ + S
Sbjct: 173 NSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVES 232
Query: 153 DRSSVLEMEKRERRALERKMSEMEEEMKNLHQLKQIQTLKQMNEQLQAE 201
++S + K +R LER + ++ + + + L+ ++ +LQA+
Sbjct: 233 EKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQ 281
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 49.3 bits (116), Expect = 3e-06
Identities = 45/227 (19%), Positives = 101/227 (44%), Gaps = 10/227 (4%)
Query: 2 DKNENEEADLDEQSSKRLSIRERRRPKERR-RGTGINFWTKDEDETDGSEEVKETWHERL 60
+K +E + EQ K E+ R +E + R W ++E + E+++E E
Sbjct: 332 EKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMW 391
Query: 61 SRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQ 120
+ E R + R + + R +E+ R+ +++ + + +
Sbjct: 392 RQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLR 451
Query: 121 KLKTKLQEAQLELADIKSKL---EKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEE 177
+++ K+QE + ++ + + K+ E+ Q+++EKT + +L+ E++ E KM EE
Sbjct: 452 EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQ-EEKMWRQEE 510
Query: 178 EMKNLHQLKQIQTLKQMNEQLQAENRALTRVVARLSESIESSDTQEL 224
+M +Q + +++ E++Q + + RL + E QE+
Sbjct: 511 KM-----WEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEV 552
Score = 35.8 bits (81), Expect = 0.030
Identities = 38/188 (20%), Positives = 77/188 (40%), Gaps = 16/188 (8%)
Query: 7 EEADLDEQSSKRLSIRERRRPKERRRGTGIN-----FWTKDEDETDGSEEVKETWHERLS 61
+E + EQ KR R+ K R + I W + E++ EE+ + E+L
Sbjct: 393 QEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMW-RQEEKIRELEEMMQDQEEKLR 451
Query: 62 RLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKL-YESALTENQ 120
+E + + +E + R EE + R K L E + E +
Sbjct: 452 EVE---------EKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQE 502
Query: 121 KLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMK 180
+ + +E E + + E+ Q+++EK ++ L ++ + + E ++ E+EE +
Sbjct: 503 EKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLG 562
Query: 181 NLHQLKQI 188
L Q ++
Sbjct: 563 KLGQKAEL 570
Score = 31.2 bits (69), Expect = 0.75
Identities = 38/179 (21%), Positives = 71/179 (39%), Gaps = 51/179 (28%)
Query: 95 TLTSRVEEDSNRDYK---KLYESALTENQ----KLKTKLQEAQL---------------- 131
T+T ++ N + + +L ES +E Q LK KL+ AQL
Sbjct: 210 TITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGK 269
Query: 132 ELADIKSKL-------------------------EKVAQQKQEKTSDRSSVLEMEKRERR 166
EL + +KL EK+ +Q+++ + E E++ R
Sbjct: 270 ELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWR 329
Query: 167 ALERKMSEMEEEMKNLH--QLKQIQTLKQMNEQLQAENRALTRVVARLSESIESSDTQE 223
E KM E EE+++ +Q + +++ E+++ + + R ++ E E QE
Sbjct: 330 Q-EEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE 387
Score = 30.8 bits (68), Expect = 0.98
Identities = 27/147 (18%), Positives = 67/147 (45%), Gaps = 22/147 (14%)
Query: 99 RVEEDSNRDYKKLYESALT---ENQKL---KTKLQEAQLELADIKSKL---EKVAQQKQE 149
R EE +K+ E L + +K+ + K+ E + ++ + + K+ E+ ++++E
Sbjct: 301 RQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEE 360
Query: 150 KTSDRSSVLEMEKRERRALERKMSEMEEEM-------------KNLHQLKQIQTLKQMNE 196
K ++ + ++ + R + K+ E EEEM + +Q + +++ +E
Sbjct: 361 KIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDE 420
Query: 197 QLQAENRALTRVVARLSESIESSDTQE 223
+++ + + R ++ E E QE
Sbjct: 421 KIREQEEEMWRQEEKIRELEEMMQDQE 447
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 49.3 bits (116), Expect = 3e-06
Identities = 39/227 (17%), Positives = 103/227 (45%), Gaps = 19/227 (8%)
Query: 1 MDKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERL 60
+++ +E+ + EQ KR E+ R +E+R+ W ++E + E+++E
Sbjct: 349 LEEKMHEQEKIREQEEKRQE-EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQ 407
Query: 61 SRLESGGSNPTT---SDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALT 117
+ E G + + RR+ + R R +E+ R+ +++ +
Sbjct: 408 EQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEE 467
Query: 118 ENQKLKTKLQEAQLELADIKSKL----------EKVAQQKQEKTSDRSSVLEMEKRERRA 167
+ + + K+ E + ++ + + K+ EK ++++EK ++ +++ ++ +
Sbjct: 468 KMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE 527
Query: 168 LERKMSEMEEEMKNLHQLKQIQTLKQMNEQLQAENRALTRVVARLSE 214
E KM E EE+M+ +Q + +++ E+++ + L + ++ E
Sbjct: 528 QEEKMCEQEEKMQ-----EQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 41.2 bits (95), Expect = 7e-04
Identities = 28/141 (19%), Positives = 65/141 (46%), Gaps = 3/141 (2%)
Query: 86 REAREARLATLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQLELADIK-SKLEKVA 144
RE E R +E+ ++ +K+ E + Q+ K QE ++ + K + E++
Sbjct: 347 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMM 406
Query: 145 QQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKNLHQ--LKQIQTLKQMNEQLQAEN 202
Q+++EK ++ + ++ E + E KM EE+++ + +Q + +++ E +Q +
Sbjct: 407 QEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQE 466
Query: 203 RALTRVVARLSESIESSDTQE 223
+ ++ E QE
Sbjct: 467 EKMGEQEGKMCEQEAKMQEQE 487
Score = 37.0 bits (84), Expect = 0.014
Identities = 26/116 (22%), Positives = 61/116 (52%), Gaps = 11/116 (9%)
Query: 94 ATLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSD 153
A L ++VEE N + +L + + + + K+QE + + I+ + EK+ +Q+++
Sbjct: 267 AKLQAQVEE--NELWNRLNQQQEEKMWRQEEKIQEREEK---IQEQEEKIREQEEKMRRQ 321
Query: 154 RSSVLEMEKRERRA------LERKMSEMEEEMKNLHQLKQIQTLKQMNEQLQAENR 203
+ E E++ RR E K+ E+EE+M ++++ + +Q E+++ + +
Sbjct: 322 EEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEK 377
Score = 32.3 bits (72), Expect = 0.34
Identities = 23/126 (18%), Positives = 62/126 (49%), Gaps = 10/126 (7%)
Query: 85 RREAREARLATLTSRVEEDSNRDYKKLYE-----SALTENQKLKTKLQEAQLELADIKSK 139
+R+ A+L +++ +++ K+L A E +L +L + Q E +
Sbjct: 236 KRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKM---WR 292
Query: 140 LEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKNLHQL--KQIQTLKQMNEQ 197
E+ Q+++EK ++ + ++ + R E M E EE+M+ ++ ++ + ++++ E+
Sbjct: 293 QEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEK 352
Query: 198 LQAENR 203
+ + +
Sbjct: 353 MHEQEK 358
Score = 30.4 bits (67), Expect = 1.3
Identities = 28/125 (22%), Positives = 59/125 (47%), Gaps = 18/125 (14%)
Query: 114 SALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSD------RSSVLEMEKRERRA 167
S L ++ K +L++A +A K K ++ ++ ++ R+++ + E +E+ A
Sbjct: 153 SRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNA 212
Query: 168 --------LERKMSEMEEEMKNLHQLKQIQTLKQMNEQLQAE----NRALTRVVARLSES 215
+E + SE++ +K L + + L +QLQAE + L V A+L
Sbjct: 213 KLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQ 272
Query: 216 IESSD 220
+E ++
Sbjct: 273 VEENE 277
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.303 0.119 0.302
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,096,198
Number of Sequences: 37866
Number of extensions: 313021
Number of successful extensions: 6579
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 456
Number of HSP's successfully gapped in prelim test: 864
Number of HSP's that attempted gapping in prelim test: 2599
Number of HSP's gapped (non-prelim): 3458
length of query: 224
length of database: 18,247,518
effective HSP length: 98
effective length of query: 126
effective length of database: 14,536,650
effective search space: 1831617900
effective search space used: 1831617900
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.