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Search of human proteins with 14195597
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14195597 protein phosphatase 1, regulatory (inhibitor)
subunit 12B isoform c [Homo sapiens]
(208 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14195597 protein phosphatase 1, regulatory (inhibitor) subuni... 401 e-112
gi|4505319 protein phosphatase 1, regulatory (inhibitor) subunit... 401 e-112
gi|14195601 protein phosphatase 1, regulatory (inhibitor) subuni... 366 e-102
gi|14195599 protein phosphatase 1, regulatory (inhibitor) subuni... 366 e-102
gi|219842214 protein phosphatase 1, regulatory (inhibitor) subun... 194 6e-50
gi|219842212 protein phosphatase 1, regulatory (inhibitor) subun... 194 6e-50
gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit... 194 6e-50
gi|14149716 protein phosphatase 1, regulatory subunit 12C [Homo ... 112 2e-25
gi|15149465 caldesmon 1 isoform 5 [Homo sapiens] 54 1e-07
gi|4826657 caldesmon 1 isoform 2 [Homo sapiens] 54 1e-07
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 53 2e-07
gi|148839339 nexilin (F actin binding protein) [Homo sapiens] 53 2e-07
gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens] 53 2e-07
gi|15149463 caldesmon 1 isoform 4 [Homo sapiens] 52 3e-07
gi|15149467 caldesmon 1 isoform 3 [Homo sapiens] 52 3e-07
gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens] 51 6e-07
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 50 1e-06
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 50 2e-06
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 50 2e-06
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 48 5e-06
gi|17865632 mitochondrial tumor suppressor 1 isoform 5 [Homo sap... 48 7e-06
gi|50348611 mitochondrial tumor suppressor 1 isoform 1 [Homo sap... 48 7e-06
gi|50348617 mitochondrial tumor suppressor 1 isoform 2 [Homo sap... 48 7e-06
gi|50348626 mitochondrial tumor suppressor 1 isoform 4 [Homo sap... 48 7e-06
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 47 9e-06
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 47 9e-06
gi|31982906 cingulin-like 1 [Homo sapiens] 47 9e-06
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 47 1e-05
gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens] 47 1e-05
gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens] 47 1e-05
>gi|14195597 protein phosphatase 1, regulatory (inhibitor) subunit
12B isoform c [Homo sapiens]
Length = 208
Score = 401 bits (1030), Expect = e-112
Identities = 208/208 (100%), Positives = 208/208 (100%)
Query: 1 MDKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERL 60
MDKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERL
Sbjct: 1 MDKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERL 60
Query: 61 SRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQ 120
SRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQ
Sbjct: 61 SRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQ 120
Query: 121 KLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMK 180
KLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMK
Sbjct: 121 KLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMK 180
Query: 181 VLTELKSDNQRLKDENGALIRVISKLSK 208
VLTELKSDNQRLKDENGALIRVISKLSK
Sbjct: 181 VLTELKSDNQRLKDENGALIRVISKLSK 208
>gi|4505319 protein phosphatase 1, regulatory (inhibitor) subunit
12B isoform a [Homo sapiens]
Length = 982
Score = 401 bits (1030), Expect = e-112
Identities = 208/208 (100%), Positives = 208/208 (100%)
Query: 1 MDKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERL 60
MDKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERL
Sbjct: 775 MDKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERL 834
Query: 61 SRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQ 120
SRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQ
Sbjct: 835 SRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQ 894
Query: 121 KLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMK 180
KLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMK
Sbjct: 895 KLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMK 954
Query: 181 VLTELKSDNQRLKDENGALIRVISKLSK 208
VLTELKSDNQRLKDENGALIRVISKLSK
Sbjct: 955 VLTELKSDNQRLKDENGALIRVISKLSK 982
>gi|14195601 protein phosphatase 1, regulatory (inhibitor) subunit
12B isoform b [Homo sapiens]
Length = 998
Score = 366 bits (940), Expect = e-102
Identities = 193/214 (90%), Positives = 201/214 (93%), Gaps = 6/214 (2%)
Query: 1 MDKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERL 60
MDKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERL
Sbjct: 775 MDKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERL 834
Query: 61 SRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQ 120
SRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQ
Sbjct: 835 SRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQ 894
Query: 121 KLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMK 180
KLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMK
Sbjct: 895 KLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMK 954
Query: 181 VLTE------LKSDNQRLKDENGALIRVISKLSK 208
L + LK N++L+ EN AL RV+++LS+
Sbjct: 955 NLHQLKQIQTLKQMNEQLQAENRALTRVVARLSE 988
>gi|14195599 protein phosphatase 1, regulatory (inhibitor) subunit
12B isoform d [Homo sapiens]
Length = 224
Score = 366 bits (940), Expect = e-102
Identities = 193/214 (90%), Positives = 201/214 (93%), Gaps = 6/214 (2%)
Query: 1 MDKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERL 60
MDKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERL
Sbjct: 1 MDKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERL 60
Query: 61 SRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQ 120
SRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQ
Sbjct: 61 SRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQ 120
Query: 121 KLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMK 180
KLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMK
Sbjct: 121 KLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMK 180
Query: 181 VLTE------LKSDNQRLKDENGALIRVISKLSK 208
L + LK N++L+ EN AL RV+++LS+
Sbjct: 181 NLHQLKQIQTLKQMNEQLQAENRALTRVVARLSE 214
>gi|219842214 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform b [Homo sapiens]
Length = 943
Score = 194 bits (492), Expect = 6e-50
Identities = 113/215 (52%), Positives = 147/215 (68%), Gaps = 19/215 (8%)
Query: 5 ENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDE--------TDGSEEVKETW 56
+ EE E S+ SIRERRRP+E+RR TG++FWT+D DE T+ KET
Sbjct: 737 KREEEKEGEDKSQPKSIRERRRPREKRRSTGVSFWTQDSDENEQEQQSDTEEGSNKKETQ 796
Query: 57 HERLSRLESGGSNPTTSDSYGDRASARARREAREARL---ATLTSRVEEDSNRDYKKLYE 113
+ +SR E T+S S GDR + R + L +SR+E+D + D+KKLYE
Sbjct: 797 TDSISRYE------TSSTSAGDRYDSLLGRSGSYSYLEERKPYSSRLEKDDSTDFKKLYE 850
Query: 114 SALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMS 173
L EN+KLK +L + +EL D+K +LEK A Q+QE+ +DR S+LEMEKRERRALER++S
Sbjct: 851 QILAENEKLKAQLHDTNMELTDLKLQLEK-ATQRQERFADR-SLLEMEKRERRALERRIS 908
Query: 174 EMEEEMKVLTELKSDNQRLKDENGALIRVISKLSK 208
EMEEE+K+L +LK+DNQRLKDENGALIRVISKLSK
Sbjct: 909 EMEEELKMLPDLKADNQRLKDENGALIRVISKLSK 943
>gi|219842212 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform a [Homo sapiens]
Length = 1030
Score = 194 bits (492), Expect = 6e-50
Identities = 113/215 (52%), Positives = 147/215 (68%), Gaps = 19/215 (8%)
Query: 5 ENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDE--------TDGSEEVKETW 56
+ EE E S+ SIRERRRP+E+RR TG++FWT+D DE T+ KET
Sbjct: 824 KREEEKEGEDKSQPKSIRERRRPREKRRSTGVSFWTQDSDENEQEQQSDTEEGSNKKETQ 883
Query: 57 HERLSRLESGGSNPTTSDSYGDRASARARREAREARL---ATLTSRVEEDSNRDYKKLYE 113
+ +SR E T+S S GDR + R + L +SR+E+D + D+KKLYE
Sbjct: 884 TDSISRYE------TSSTSAGDRYDSLLGRSGSYSYLEERKPYSSRLEKDDSTDFKKLYE 937
Query: 114 SALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMS 173
L EN+KLK +L + +EL D+K +LEK A Q+QE+ +DR S+LEMEKRERRALER++S
Sbjct: 938 QILAENEKLKAQLHDTNMELTDLKLQLEK-ATQRQERFADR-SLLEMEKRERRALERRIS 995
Query: 174 EMEEEMKVLTELKSDNQRLKDENGALIRVISKLSK 208
EMEEE+K+L +LK+DNQRLKDENGALIRVISKLSK
Sbjct: 996 EMEEELKMLPDLKADNQRLKDENGALIRVISKLSK 1030
>gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit 12A
isoform a [Homo sapiens]
Length = 1030
Score = 194 bits (492), Expect = 6e-50
Identities = 113/215 (52%), Positives = 147/215 (68%), Gaps = 19/215 (8%)
Query: 5 ENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDE--------TDGSEEVKETW 56
+ EE E S+ SIRERRRP+E+RR TG++FWT+D DE T+ KET
Sbjct: 824 KREEEKEGEDKSQPKSIRERRRPREKRRSTGVSFWTQDSDENEQEQQSDTEEGSNKKETQ 883
Query: 57 HERLSRLESGGSNPTTSDSYGDRASARARREAREARL---ATLTSRVEEDSNRDYKKLYE 113
+ +SR E T+S S GDR + R + L +SR+E+D + D+KKLYE
Sbjct: 884 TDSISRYE------TSSTSAGDRYDSLLGRSGSYSYLEERKPYSSRLEKDDSTDFKKLYE 937
Query: 114 SALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMS 173
L EN+KLK +L + +EL D+K +LEK A Q+QE+ +DR S+LEMEKRERRALER++S
Sbjct: 938 QILAENEKLKAQLHDTNMELTDLKLQLEK-ATQRQERFADR-SLLEMEKRERRALERRIS 995
Query: 174 EMEEEMKVLTELKSDNQRLKDENGALIRVISKLSK 208
EMEEE+K+L +LK+DNQRLKDENGALIRVISKLSK
Sbjct: 996 EMEEELKMLPDLKADNQRLKDENGALIRVISKLSK 1030
>gi|14149716 protein phosphatase 1, regulatory subunit 12C [Homo
sapiens]
Length = 782
Score = 112 bits (281), Expect = 2e-25
Identities = 61/125 (48%), Positives = 88/125 (70%), Gaps = 1/125 (0%)
Query: 84 ARREAREARLATLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQLELADIKSKLEKV 143
ARR+ + L E+ + ++ LY EN++L+ L E L LA +K +LE+
Sbjct: 659 ARRQRWQRDLNPEPEPESEEPDGGFRTLYAELRRENERLREALTETTLRLAQLKVELER- 717
Query: 144 AQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKVLTELKSDNQRLKDENGALIRVI 203
A Q+QE+ ++R ++LE+E+ ERRALERK +E+EEE+K L++L++DNQRLKDEN ALIRVI
Sbjct: 718 ATQRQERFAERPALLELERFERRALERKAAELEEELKALSDLRADNQRLKDENAALIRVI 777
Query: 204 SKLSK 208
SKLSK
Sbjct: 778 SKLSK 782
>gi|15149465 caldesmon 1 isoform 5 [Homo sapiens]
Length = 532
Score = 53.5 bits (127), Expect = 1e-07
Identities = 60/211 (28%), Positives = 95/211 (45%), Gaps = 35/211 (16%)
Query: 3 KNENEEADLDEQSSKRLSIRER----------RRPKERRRGTGINFWTKDEDETDGSEEV 52
K + E+ + +E+ KR SI E + PKE + +F + + T+ +
Sbjct: 179 KEDKEKEEEEEEKPKRGSIGENQIKDEKIKKDKEPKEEVK----SFMDRKKGFTEVKSQN 234
Query: 53 KETWHERLSRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLY 112
E +L E+ S P G RAS + EA A R+EE R
Sbjct: 235 GEFMTHKLKHTENTFSRP------GGRASVDTK-EAEGAPQVEAGKRLEELRRRRG---- 283
Query: 113 ESALTENQKLKTKLQEAQLELADIKSK-------LEKVAQQKQEKTSDRSSVLEMEKRE- 164
E+ E +KLK K QEA LEL ++K K LE+ Q+++++ +DR E EKR
Sbjct: 284 ETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRL 343
Query: 165 RRALERKMSEMEEEMKVLTE--LKSDNQRLK 193
+ +ER+ +E E+ + + E L D + K
Sbjct: 344 KEEIERRRAEAAEKRQKMPEDGLSDDKKPFK 374
Score = 30.0 bits (66), Expect = 1.5
Identities = 20/90 (22%), Positives = 39/90 (43%)
Query: 73 SDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQLE 132
+D + A+ RR AR+ RL D ++ +++ KT Q+E
Sbjct: 24 NDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVE 83
Query: 133 LADIKSKLEKVAQQKQEKTSDRSSVLEMEK 162
D + LE++A++++ + LE +K
Sbjct: 84 GDDEAAFLERLARREERRQKRLQEALERQK 113
>gi|4826657 caldesmon 1 isoform 2 [Homo sapiens]
Length = 538
Score = 53.5 bits (127), Expect = 1e-07
Identities = 60/211 (28%), Positives = 95/211 (45%), Gaps = 35/211 (16%)
Query: 3 KNENEEADLDEQSSKRLSIRER----------RRPKERRRGTGINFWTKDEDETDGSEEV 52
K + E+ + +E+ KR SI E + PKE + +F + + T+ +
Sbjct: 185 KEDKEKEEEEEEKPKRGSIGENQIKDEKIKKDKEPKEEVK----SFMDRKKGFTEVKSQN 240
Query: 53 KETWHERLSRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLY 112
E +L E+ S P G RAS + EA A R+EE R
Sbjct: 241 GEFMTHKLKHTENTFSRP------GGRASVDTK-EAEGAPQVEAGKRLEELRRRRG---- 289
Query: 113 ESALTENQKLKTKLQEAQLELADIKSK-------LEKVAQQKQEKTSDRSSVLEMEKRE- 164
E+ E +KLK K QEA LEL ++K K LE+ Q+++++ +DR E EKR
Sbjct: 290 ETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRL 349
Query: 165 RRALERKMSEMEEEMKVLTE--LKSDNQRLK 193
+ +ER+ +E E+ + + E L D + K
Sbjct: 350 KEEIERRRAEAAEKRQKMPEDGLSDDKKPFK 380
Score = 32.3 bits (72), Expect = 0.29
Identities = 26/119 (21%), Positives = 51/119 (42%), Gaps = 1/119 (0%)
Query: 44 DETDGSEEVKETWHERLSRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEED 103
D+ + E++ E + RLE+ +D + A+ RR AR+ RL
Sbjct: 2 DDFERRRELRRQKREEM-RLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLG 60
Query: 104 SNRDYKKLYESALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEK 162
D ++ +++ KT Q+E D + LE++A++++ + LE +K
Sbjct: 61 QVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQK 119
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 53.1 bits (126), Expect = 2e-07
Identities = 50/194 (25%), Positives = 89/194 (45%), Gaps = 16/194 (8%)
Query: 7 EEADLDEQSSKRLSIRERRRPKERRRGTG-INFWTKDEDETDGSEEVKETWHERLSRLES 65
EE + + ++S E ++ +ER +G+ I+ K E EE KE +RLE+
Sbjct: 221 EETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKME------EEDKERAEAERARLEA 274
Query: 66 GGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQKLKTK 125
++ A RAR EA E A R E + ++ + A E Q++K +
Sbjct: 275 EERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEE 334
Query: 126 LQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKVLTEL 185
+ A E IK + ++ A+++Q E+ +R A ER+ + EEE K E
Sbjct: 335 EKRAAEERQRIKEEEKRAAEERQR---------IKEEEKRAAEERQRARAEEEEKAKVEE 385
Query: 186 KSDNQRLKDENGAL 199
+ N++L+++ A+
Sbjct: 386 QKRNKQLEEKKHAM 399
Score = 52.4 bits (124), Expect = 3e-07
Identities = 55/202 (27%), Positives = 93/202 (46%), Gaps = 25/202 (12%)
Query: 2 DKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLS 61
+K + ++ ++ K I++ + PKE + +F + + T+ + E +L
Sbjct: 449 EKLQEDKPTFKKEEIKDEKIKKDKEPKEEVK----SFMDRKKGFTEVKSQNGEFMTHKLK 504
Query: 62 RLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQK 121
E+ S P G RAS + EA A R+EE R E+ E +K
Sbjct: 505 HTENTFSRP------GGRASVDTK-EAEGAPQVEAGKRLEELRRRRG----ETESEEFEK 553
Query: 122 LKTKLQEAQLELADIKSK-------LEKVAQQKQEKTSDRSSVLEMEKRE-RRALERKMS 173
LK K QEA LEL ++K K LE+ Q+++++ +DR E EKR + +ER+ +
Sbjct: 554 LKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRA 613
Query: 174 EMEEEMKVLTE--LKSDNQRLK 193
E E+ + + E L D + K
Sbjct: 614 EAAEKRQKMPEDGLSDDKKPFK 635
Score = 43.9 bits (102), Expect = 1e-04
Identities = 44/199 (22%), Positives = 91/199 (45%), Gaps = 9/199 (4%)
Query: 2 DKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLS 61
D ENE + +E+S R E + + N W +D +E ++ KE E
Sbjct: 140 DTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDW-RDAEENKKEDKEKEEEEEEKP 198
Query: 62 RLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQK 121
+ S G N + + + ++ E L EE + ++ ++ ++K
Sbjct: 199 KRGSIGENQV--EVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEK 256
Query: 122 LKTKLQE-AQLELADIKS-KLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEM 179
++ + +E A+ E A +++ + E++ ++ +K +D + +E E++ A ER+ E EE
Sbjct: 257 MEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEK-AAAQERERREAEERE 315
Query: 180 KVLTELK---SDNQRLKDE 195
++ E K + QR+K+E
Sbjct: 316 RMREEEKRAAEERQRIKEE 334
Score = 41.6 bits (96), Expect = 5e-04
Identities = 45/194 (23%), Positives = 79/194 (40%), Gaps = 20/194 (10%)
Query: 3 KNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLSR 62
K +E A ++ + RERR +ER R E+E +EE +R+
Sbjct: 287 KIADERARIEAEEKAAAQERERREAEERER--------MREEEKRAAEE-----RQRIKE 333
Query: 63 LESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQKL 122
E + ++ +A R+ +E R E+ R + E A E QK
Sbjct: 334 EEKRAAEERQRIKEEEKRAAEERQRIKEEE-----KRAAEERQRARAEEEEKAKVEEQKR 388
Query: 123 KTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKVL 182
+L+E + + + K K EKV Q+ + K + E +K + L+++ E +++
Sbjct: 389 NKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQE-DKLQTAVLKKQGEEKGTKVQAK 447
Query: 183 TE-LKSDNQRLKDE 195
E L+ D K E
Sbjct: 448 REKLQEDKPTFKKE 461
Score = 32.3 bits (72), Expect = 0.29
Identities = 26/119 (21%), Positives = 51/119 (42%), Gaps = 1/119 (0%)
Query: 44 DETDGSEEVKETWHERLSRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEED 103
D+ + E++ E + RLE+ +D + A+ RR AR+ RL
Sbjct: 2 DDFERRRELRRQKREEM-RLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLG 60
Query: 104 SNRDYKKLYESALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEK 162
D ++ +++ KT Q+E D + LE++A++++ + LE +K
Sbjct: 61 QVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQK 119
Score = 28.5 bits (62), Expect = 4.2
Identities = 33/160 (20%), Positives = 63/160 (39%), Gaps = 6/160 (3%)
Query: 2 DKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVK-ETWHERL 60
+K EE ++ KR + +R +E +R K+E++ E + E
Sbjct: 321 EKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEK 380
Query: 61 SRLESGGSNPTTSDSYGDRASARARREAREARLA---TLTSRVEEDSNRD--YKKLYESA 115
+++E N + + + E E ++ + +ED + KK E
Sbjct: 381 AKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEK 440
Query: 116 LTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRS 155
T+ Q + KLQE + + K EK+ + K+ K +S
Sbjct: 441 GTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKS 480
>gi|148839339 nexilin (F actin binding protein) [Homo sapiens]
Length = 675
Score = 53.1 bits (126), Expect = 2e-07
Identities = 51/210 (24%), Positives = 93/210 (44%), Gaps = 20/210 (9%)
Query: 3 KNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLSR 62
+ EN + +E++ KRL E +R E R +N +++E + ++ + + +
Sbjct: 258 RQENRKKQAEEEARKRLE--EEKRAFEEARRQMVN----EDEENQDTAKIFKGYRPGKLK 311
Query: 63 LESGGSNPTTSDSYGDRASARARREAREARLATLTSR----VEEDSNRDYKKLYESALTE 118
L + +A ARR E + A +R V++DS YK + + LT
Sbjct: 312 LSFEEMERQRREDEKRKAEEEARRRIEEEKKAFAEARRNMVVDDDSPEMYKTISQEFLTP 371
Query: 119 NQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEE 178
KL+ +E +K K+E ++K+ +R LEMEK+E L ++M E EEE
Sbjct: 372 G-KLEINFEEL------LKQKME---EEKRRTEEERKHKLEMEKQEFEQLRQEMGEEEEE 421
Query: 179 MKVLTELKSDNQRLKDENGALIRVISKLSK 208
+ + + +K + I+ + SK
Sbjct: 422 NETFGLSREYEELIKLKRSGSIQAKNLKSK 451
Score = 34.7 bits (78), Expect = 0.059
Identities = 28/168 (16%), Positives = 74/168 (44%), Gaps = 5/168 (2%)
Query: 41 KDEDETDGSEEVKETWHERLSRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRV 100
K E S+ V +T+ +L + + + +R R+R E + + + R
Sbjct: 7 KAEILLSSSKPVPKTYVPKLGKGDVKDKFEAMQRAREERNQRRSRDEKQRRKEQYIRERE 66
Query: 101 EEDSNRDYKKLYESALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEK-----TSDRS 155
++ K++ S E+ K + +K + ++ +Q+QE+ +R
Sbjct: 67 WNRRKQEIKEMLASDDEEDVSSKVEKAYVPKLTGTVKGRFAEMEKQRQEEQRKRTEEERK 126
Query: 156 SVLEMEKRERRALERKMSEMEEEMKVLTELKSDNQRLKDENGALIRVI 203
+E + E+R ++R++++ E+++ + +++ + ++ LI V+
Sbjct: 127 RRIEQDMLEKRKIQRELAKRAEQIEDINNTGTESASEEGDDSLLITVV 174
Score = 30.8 bits (68), Expect = 0.85
Identities = 34/191 (17%), Positives = 79/191 (41%), Gaps = 12/191 (6%)
Query: 18 RLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLSRLESGGSNPTTSDSY- 76
R + E++R +E+R+ T + E + +++ +R ++E + T S S
Sbjct: 105 RFAEMEKQRQEEQRKRTEEERKRRIEQDMLEKRKIQRELAKRAEQIEDINNTGTESASEE 164
Query: 77 GDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQLELA-- 134
GD + + + + + ED ++ ++ E+++++ + Q L+ A
Sbjct: 165 GDDSLLITVVPVKSYKTSGKMKKNFEDLEKEREEKERIKYEEDKRIRYEEQRPSLKEAKC 224
Query: 135 ---------DIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKVLTEL 185
+ ++K E ++ K + T + E R+++A E +EEE + E
Sbjct: 225 LSLVMDDEIESEAKKESLSPGKLKLTFEELERQRQENRKKQAEEEARKRLEEEKRAFEEA 284
Query: 186 KSDNQRLKDEN 196
+ +EN
Sbjct: 285 RRQMVNEDEEN 295
Score = 28.5 bits (62), Expect = 4.2
Identities = 39/187 (20%), Positives = 74/187 (39%), Gaps = 43/187 (22%)
Query: 3 KNENEEADLDEQSSKRLSIRERRRPKERRRGTGIN-------------FWTKDEDETDGS 49
+ E+E+ +E++ +R+ E++ E RR ++ F T + E +
Sbjct: 321 RREDEKRKAEEEARRRIE-EEKKAFAEARRNMVVDDDSPEMYKTISQEFLTPGKLEINFE 379
Query: 50 EEVKETWHERLSRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDY- 108
E +K+ E R E + + E +E EE+ N +
Sbjct: 380 ELLKQKMEEEKRRTE-------------EERKHKLEMEKQEFEQLRQEMGEEEEENETFG 426
Query: 109 -KKLYESALTENQKLKTKLQEAQLELADIKSKLEKVAQ-------QKQEKTSDRSSVLEM 160
+ YE + KLK + ++ ++KSK EK+ Q +K E+ R +++
Sbjct: 427 LSREYEELI----KLK---RSGSIQAKNLKSKFEKIGQLSEKEIQKKIEEERARRRAIDL 479
Query: 161 EKRERRA 167
E +ER A
Sbjct: 480 EIKEREA 486
>gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens]
Length = 284
Score = 52.8 bits (125), Expect = 2e-07
Identities = 60/207 (28%), Positives = 102/207 (49%), Gaps = 39/207 (18%)
Query: 1 MDKNENEEADLDEQSSKRLSIRERRRPKERR-RGTGINFWTKDEDETDG-SEEVKETWHE 58
+D+ E EAD + + + E ++ +++ +GT EDE + SE VKE E
Sbjct: 19 IDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGT--------EDEVEKYSESVKEA-QE 69
Query: 59 RLSRLESGGSNPTTSDSYGDRASARARREAREA-------RLATLTSRVEE------DSN 105
+L + E +D+ D AS R + E RLAT ++EE +S
Sbjct: 70 KLEQAEK-----KATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESE 124
Query: 106 RDYKKLYESALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLE--MEKR 163
R K + A+ + +K++ LQE QL+ A + + + +K E+ + + +LE +E+
Sbjct: 125 RGMKVIENRAMKDEEKME--LQEMQLKEA---KHIAEDSDRKYEEVARKLVILEGELERS 179
Query: 164 ERRA--LERKMSEMEEEMKVLT-ELKS 187
E RA E K ++EEE+K++T LKS
Sbjct: 180 EERAEVAESKCGDLEEELKIVTNNLKS 206
Score = 30.8 bits (68), Expect = 0.85
Identities = 20/95 (21%), Positives = 44/95 (46%), Gaps = 1/95 (1%)
Query: 109 KKLYESALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRAL 168
K+L E +KLK E + +K EK+ Q +++ T + V + +R + +
Sbjct: 37 KQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRR-IQLV 95
Query: 169 ERKMSEMEEEMKVLTELKSDNQRLKDENGALIRVI 203
E ++ +E + + + ++ DE+ ++VI
Sbjct: 96 EEELDRAQERLATALQKLEEAEKAADESERGMKVI 130
Score = 28.5 bits (62), Expect = 4.2
Identities = 18/69 (26%), Positives = 39/69 (56%), Gaps = 4/69 (5%)
Query: 122 LKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKV 181
+K K+Q +L+ + + E+ A+ +++ DR LE E++AL++K+ E+E++
Sbjct: 4 IKKKMQMLKLDKENAIDRAEQ-AEADKKQAEDRCKQLE---EEQQALQKKLKGTEDEVEK 59
Query: 182 LTELKSDNQ 190
+E + Q
Sbjct: 60 YSESVKEAQ 68
>gi|15149463 caldesmon 1 isoform 4 [Homo sapiens]
Length = 558
Score = 52.4 bits (124), Expect = 3e-07
Identities = 55/202 (27%), Positives = 93/202 (46%), Gaps = 25/202 (12%)
Query: 2 DKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLS 61
+K + ++ ++ K I++ + PKE + +F + + T+ + E +L
Sbjct: 214 EKLQEDKPTFKKEEIKDEKIKKDKEPKEEVK----SFMDRKKGFTEVKSQNGEFMTHKLK 269
Query: 62 RLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQK 121
E+ S P G RAS + EA A R+EE R E+ E +K
Sbjct: 270 HTENTFSRP------GGRASVDTK-EAEGAPQVEAGKRLEELRRRRG----ETESEEFEK 318
Query: 122 LKTKLQEAQLELADIKSK-------LEKVAQQKQEKTSDRSSVLEMEKRE-RRALERKMS 173
LK K QEA LEL ++K K LE+ Q+++++ +DR E EKR + +ER+ +
Sbjct: 319 LKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRA 378
Query: 174 EMEEEMKVLTE--LKSDNQRLK 193
E E+ + + E L D + K
Sbjct: 379 EAAEKRQKMPEDGLSDDKKPFK 400
Score = 33.1 bits (74), Expect = 0.17
Identities = 44/217 (20%), Positives = 79/217 (36%), Gaps = 22/217 (10%)
Query: 3 KNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLSR 62
+ + EE L + + + + P E + T N + +DE E + R R
Sbjct: 45 RQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKR 104
Query: 63 LESGGS-----NPTTSDSYGDRASARARREAREARLATLTSRVE-----------EDSNR 106
L+ +PT +D+ S R + + E + E E +
Sbjct: 105 LQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTK 164
Query: 107 DYKKLYESALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERR 166
Y+K EN+K + +E + E S E ++K K + L+ +K +
Sbjct: 165 SYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFK 224
Query: 167 ALE------RKMSEMEEEMKVLTELKSDNQRLKDENG 197
E +K E +EE+K + K +K +NG
Sbjct: 225 KEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNG 261
Score = 31.6 bits (70), Expect = 0.50
Identities = 47/227 (20%), Positives = 85/227 (37%), Gaps = 39/227 (17%)
Query: 2 DKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLS 61
D ENE + +E+S R E + + N W D + +E KE E
Sbjct: 134 DTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDW---RDAEENKKEDKEKEEEEEE 190
Query: 62 RLESGGSNPTTSDSYGDRASAR-----------ARREAREARLATLTSRVEE-DSNRDYK 109
+ + G + G + A+ + E ++ ++ EE S D K
Sbjct: 191 KPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRK 250
Query: 110 KLYESALTENQKLKT-KLQEAQLELA-------------------DIKSKLEKVAQQKQE 149
K + ++N + T KL+ + + + +LE++ +++ E
Sbjct: 251 KGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGE 310
Query: 150 KTSDRSSVLEMEKRERR-ALERKMSEMEEEMKVLTELKSDNQRLKDE 195
S+ L+ +++E LE + EE KVL E + QR K E
Sbjct: 311 TESEEFEKLKQKQQEAALELEELKKKREERRKVLEE---EEQRRKQE 354
Score = 30.4 bits (67), Expect = 1.1
Identities = 43/209 (20%), Positives = 92/209 (44%), Gaps = 31/209 (14%)
Query: 3 KNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLSR 62
K + E+ + +E+ KR SI E + ++ + +++ T EE+K+ +
Sbjct: 179 KEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKD------EK 232
Query: 63 LESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDS--------NRDYKKLYES 114
++ S+ DR +++ T + E++ + D K+ +
Sbjct: 233 IKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGA 292
Query: 115 ALTENQKLKTKLQEAQLELADIKSK-LEKVAQQKQEKTSDRSSVLEMEK-RERRALERKM 172
E K +L+E + + +S+ EK+ Q++QE + LE+E+ +++R RK+
Sbjct: 293 PQVEAGK---RLEELRRRRGETESEEFEKLKQKQQE------AALELEELKKKREERRKV 343
Query: 173 SEMEEEMKVLTEL------KSDNQRLKDE 195
E EE+ + E + + +RLK+E
Sbjct: 344 LEEEEQRRKQEEADRKLREEEEKRRLKEE 372
>gi|15149467 caldesmon 1 isoform 3 [Homo sapiens]
Length = 564
Score = 52.4 bits (124), Expect = 3e-07
Identities = 55/202 (27%), Positives = 93/202 (46%), Gaps = 25/202 (12%)
Query: 2 DKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLS 61
+K + ++ ++ K I++ + PKE + +F + + T+ + E +L
Sbjct: 220 EKLQEDKPTFKKEEIKDEKIKKDKEPKEEVK----SFMDRKKGFTEVKSQNGEFMTHKLK 275
Query: 62 RLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQK 121
E+ S P G RAS + EA A R+EE R E+ E +K
Sbjct: 276 HTENTFSRP------GGRASVDTK-EAEGAPQVEAGKRLEELRRRRG----ETESEEFEK 324
Query: 122 LKTKLQEAQLELADIKSK-------LEKVAQQKQEKTSDRSSVLEMEKRE-RRALERKMS 173
LK K QEA LEL ++K K LE+ Q+++++ +DR E EKR + +ER+ +
Sbjct: 325 LKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRA 384
Query: 174 EMEEEMKVLTE--LKSDNQRLK 193
E E+ + + E L D + K
Sbjct: 385 EAAEKRQKMPEDGLSDDKKPFK 406
Score = 33.1 bits (74), Expect = 0.17
Identities = 44/217 (20%), Positives = 79/217 (36%), Gaps = 22/217 (10%)
Query: 3 KNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLSR 62
+ + EE L + + + + P E + T N + +DE E + R R
Sbjct: 51 RQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKR 110
Query: 63 LESGGS-----NPTTSDSYGDRASARARREAREARLATLTSRVE-----------EDSNR 106
L+ +PT +D+ S R + + E + E E +
Sbjct: 111 LQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTK 170
Query: 107 DYKKLYESALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERR 166
Y+K EN+K + +E + E S E ++K K + L+ +K +
Sbjct: 171 SYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFK 230
Query: 167 ALE------RKMSEMEEEMKVLTELKSDNQRLKDENG 197
E +K E +EE+K + K +K +NG
Sbjct: 231 KEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNG 267
Score = 31.6 bits (70), Expect = 0.50
Identities = 47/227 (20%), Positives = 85/227 (37%), Gaps = 39/227 (17%)
Query: 2 DKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLS 61
D ENE + +E+S R E + + N W D + +E KE E
Sbjct: 140 DTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDW---RDAEENKKEDKEKEEEEEE 196
Query: 62 RLESGGSNPTTSDSYGDRASAR-----------ARREAREARLATLTSRVEE-DSNRDYK 109
+ + G + G + A+ + E ++ ++ EE S D K
Sbjct: 197 KPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRK 256
Query: 110 KLYESALTENQKLKT-KLQEAQLELA-------------------DIKSKLEKVAQQKQE 149
K + ++N + T KL+ + + + +LE++ +++ E
Sbjct: 257 KGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGE 316
Query: 150 KTSDRSSVLEMEKRERR-ALERKMSEMEEEMKVLTELKSDNQRLKDE 195
S+ L+ +++E LE + EE KVL E + QR K E
Sbjct: 317 TESEEFEKLKQKQQEAALELEELKKKREERRKVLEE---EEQRRKQE 360
Score = 30.4 bits (67), Expect = 1.1
Identities = 43/209 (20%), Positives = 92/209 (44%), Gaps = 31/209 (14%)
Query: 3 KNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLSR 62
K + E+ + +E+ KR SI E + ++ + +++ T EE+K+ +
Sbjct: 185 KEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKD------EK 238
Query: 63 LESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDS--------NRDYKKLYES 114
++ S+ DR +++ T + E++ + D K+ +
Sbjct: 239 IKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGA 298
Query: 115 ALTENQKLKTKLQEAQLELADIKSK-LEKVAQQKQEKTSDRSSVLEMEK-RERRALERKM 172
E K +L+E + + +S+ EK+ Q++QE + LE+E+ +++R RK+
Sbjct: 299 PQVEAGK---RLEELRRRRGETESEEFEKLKQKQQE------AALELEELKKKREERRKV 349
Query: 173 SEMEEEMKVLTEL------KSDNQRLKDE 195
E EE+ + E + + +RLK+E
Sbjct: 350 LEEEEQRRKQEEADRKLREEEEKRRLKEE 378
>gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens]
Length = 285
Score = 51.2 bits (121), Expect = 6e-07
Identities = 60/202 (29%), Positives = 96/202 (47%), Gaps = 29/202 (14%)
Query: 1 MDKNENEEADLD--EQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHE 58
+D+ E EA+ E+ SK+L E +++ +GT EDE D E + E
Sbjct: 20 LDRAEQAEAEQKQAEERSKQLE-DELAAMQKKLKGT--------EDELDKYSEALKDAQE 70
Query: 59 RLSRLESGGSNPTTSDSYGDRASARARREAREA--RLATLTSRVEE------DSNRDYKK 110
+L E ++ + +R E A RLAT ++EE +S R K
Sbjct: 71 KLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKV 130
Query: 111 LYESALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLE--MEKRERRA- 167
+ AL + +K++ LQE QL+ A + + A +K E+ + + ++E +E+ E RA
Sbjct: 131 IENRALKDEEKME--LQEIQLKEA---KHIAEEADRKYEEVARKLVIIEGDLERTEERAE 185
Query: 168 -LERKMSEMEEEMK-VLTELKS 187
E K SE+EEE+K V LKS
Sbjct: 186 LAESKCSELEEELKNVTNNLKS 207
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 50.4 bits (119), Expect = 1e-06
Identities = 46/193 (23%), Positives = 79/193 (40%), Gaps = 7/193 (3%)
Query: 2 DKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLS 61
++ E + E+ +R RER + KER R +D D E ++ ER
Sbjct: 313 ERERERERERREREREREREREREKEKERERER-----ERDRDRDRTKERDRDRDRERDR 367
Query: 62 RLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQK 121
+ S+ D R +R R RE R E ++ E +K
Sbjct: 368 DRDRERSSDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREK 427
Query: 122 LKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKV 181
K + +E E A + KLE+ ++K+ +R E+ +R++ K +E EEE +
Sbjct: 428 DKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERR- 486
Query: 182 LTELKSDNQRLKD 194
E+ + +RLK+
Sbjct: 487 -REMAKEAKRLKE 498
Score = 43.1 bits (100), Expect = 2e-04
Identities = 53/214 (24%), Positives = 86/214 (40%), Gaps = 48/214 (22%)
Query: 3 KNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSE---------EVK 53
+ E E E+ +R RER R K+++R ++EDE D E E +
Sbjct: 402 EREREREREREREREREREREREREKDKKRD-------REEDEEDAYERRKLERKLREKE 454
Query: 54 ETWHERLSRLESGGSNPTTS-DSYGDRASARARREAREA-RLATLTSRVEEDSN------ 105
+ ERL E T + +R R R A+EA RL ++D +
Sbjct: 455 AAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYR 514
Query: 106 --------RDYKKLYESALTENQKLKTKLQE--------------AQLELADIKSKLEKV 143
RD +K E+ + ++ K +L+E A+L+ + +++ +
Sbjct: 515 GSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQ 574
Query: 144 AQQKQEKTSDRSSVLEMEKRERRALERKMSEMEE 177
Q KQE S+ + EK E+R E M E EE
Sbjct: 575 PQIKQEPESEEEEEEKQEKEEKR--EEPMEEEEE 606
Score = 37.4 bits (85), Expect = 0.009
Identities = 39/181 (21%), Positives = 75/181 (41%), Gaps = 13/181 (7%)
Query: 2 DKNENEEADLD---EQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHE 58
D++ + E D E+ +R RER R +ER R + E E D + +E +
Sbjct: 380 DRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEED 439
Query: 59 RLSRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTE 118
R + +Y +R RE ++ R + EE+ R+ K E
Sbjct: 440 AYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAK-------E 492
Query: 119 NQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEE 178
++LK L++ + D K Q++ DR +E ++R+R+ + ++ E+ +
Sbjct: 493 AKRLKEFLEDYDDDRDDPKYYRGSALQKRLR---DREKEMEADERDRKREKEELEEIRQR 549
Query: 179 M 179
+
Sbjct: 550 L 550
Score = 32.3 bits (72), Expect = 0.29
Identities = 46/202 (22%), Positives = 85/202 (42%), Gaps = 22/202 (10%)
Query: 8 EADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLSRLESGG 67
+A LDE +K+ + RP+ T + DE ET +++ + E L R S
Sbjct: 166 KAQLDEWKAKKKASNGNARPETV---TNDDEEALDE-ETKRRDQMIKGAIEVLIREYSSE 221
Query: 68 SNPTTSDSYGDRASARARREARE--------ARLATLTSRVEEDSN-----RDYKKLYES 114
N + +S D + ++E +E A L +ED N D + L
Sbjct: 222 LNAPSQES--DSHPRKKKKEKKEDIFRRFPVAPLIPYPLITKEDINAIEMEEDKRDLISR 279
Query: 115 ALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSE 174
+++ + KL+E + + + ++EK +++E+ +R E +RER + E
Sbjct: 280 EISKFRDTHKKLEEEKGKKEKERQEIEK---ERRERERERERERERRERERERERERERE 336
Query: 175 MEEEMKVLTELKSDNQRLKDEN 196
E+E + E D R K+ +
Sbjct: 337 KEKERERERERDRDRDRTKERD 358
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 49.7 bits (117), Expect = 2e-06
Identities = 47/201 (23%), Positives = 90/201 (44%), Gaps = 25/201 (12%)
Query: 3 KNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLSR 62
+ E + DLD +K + I+E+ + + + G + T+ E+ ++V ET
Sbjct: 1409 EKETIQKDLD---AKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMET------S 1459
Query: 63 LESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQKL 122
+S G + S + + E + +L S+VE + L+E +
Sbjct: 1460 AQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVEN---------LQKTLSEKETE 1510
Query: 123 KTKLQEAQLELADIKSKLEKVAQQKQEKTSD----RSSVLEMEKRERRALERKMSEMEEE 178
LQE ++L +S+L ++ Q Q++T+ R + E E++ R+A+ S++
Sbjct: 1511 ARNLQEQTVQL---QSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHL 1567
Query: 179 MKVLTELKSDNQRLKDENGAL 199
V +L +N+ LK NGAL
Sbjct: 1568 AGVKDQLTKENEELKQRNGAL 1588
Score = 36.2 bits (82), Expect = 0.020
Identities = 40/185 (21%), Positives = 78/185 (42%), Gaps = 36/185 (19%)
Query: 29 ERRRGTGINFWTKDEDETDGSEEVKETWHERLSRLE----------SGGSNPTTSDSYGD 78
+R+ T N ++ +++ T + LS +E +G P+ + D
Sbjct: 877 KRQLDTETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQPSNKEDVDD 936
Query: 79 RASARARREAR----EARLATLTSRVE---------EDSNRDYKKLYESALTENQKLKTK 125
S + E + + RL T TS VE E+S K++ E + ++ +
Sbjct: 937 LVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEV---RKNIEVR 993
Query: 126 LQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKVLTEL 185
L+E+ ++ KL +V ++KQE D+ RRA+E ++ E K L+ +
Sbjct: 994 LKESAEFQTQLEKKLMEVEKEKQELQDDK----------RRAIESMEQQLSELKKTLSSV 1043
Query: 186 KSDNQ 190
+++ Q
Sbjct: 1044 QNEVQ 1048
Score = 33.5 bits (75), Expect = 0.13
Identities = 26/111 (23%), Positives = 50/111 (45%), Gaps = 1/111 (0%)
Query: 89 REARLATLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQ 148
RE +A V + + Y++ E E Q+L+ L A+ E + +K ++
Sbjct: 1205 REKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLN-AEREKVQVTAKTMAQHEELM 1263
Query: 149 EKTSDRSSVLEMEKRERRALERKMSEMEEEMKVLTELKSDNQRLKDENGAL 199
+KT + V+E K R ER ++++ + +L+ D L++ N L
Sbjct: 1264 KKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAEL 1314
Score = 32.0 bits (71), Expect = 0.38
Identities = 21/86 (24%), Positives = 42/86 (48%), Gaps = 7/86 (8%)
Query: 121 KLKTKLQEAQLELADIKSKLEKVAQQKQE-------KTSDRSSVLEMEKRERRALERKMS 173
KL+ L + Q E+ +K + EK + ++ + S L E RE ++L ++
Sbjct: 24 KLEKFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKRLSHSQERLVNETRECQSLRLELE 83
Query: 174 EMEEEMKVLTELKSDNQRLKDENGAL 199
++ ++K LTE + + +D N A+
Sbjct: 84 KLNNQLKALTEKNKELEIAQDRNIAI 109
Score = 32.0 bits (71), Expect = 0.38
Identities = 24/87 (27%), Positives = 44/87 (50%), Gaps = 14/87 (16%)
Query: 112 YESALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERK 171
YE A L KL++A E+ + Q+ +K + +SSVLE R+ R +E +
Sbjct: 444 YERAQKAVASLSVKLEQAMKEIQRL--------QEDTDKANKQSSVLE---RDNRRMEIQ 492
Query: 172 MSEMEEEMKVL---TELKSDNQRLKDE 195
+ ++ ++++VL E N ++DE
Sbjct: 493 VKDLSQQIRVLLMELEEARGNHVIRDE 519
Score = 27.7 bits (60), Expect = 7.2
Identities = 44/197 (22%), Positives = 77/197 (39%), Gaps = 36/197 (18%)
Query: 2 DKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKD----EDETDGSEEVKETWH 57
+K ENE+ +EQ K R + + T ++F +K +D +G + H
Sbjct: 685 EKAENEKIQ-NEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLH 743
Query: 58 ERLSRLESGGS------NPTTSDSYGDR-----ASARARREAREARLATLTSRVEEDSNR 106
ER +L + N T D G A RA +E + L S V R
Sbjct: 744 ERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKKEKEMLKL-SEVRLSQQR 802
Query: 107 D------------------YKKLYESALTEN-QKLKTKLQEAQLELADIKSKLEKVAQQK 147
+ + + E + TE Q+L +++++ + E++ +K KLE +Q+
Sbjct: 803 ESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEISHLKKKLENEVEQR 862
Query: 148 QEKTSDRSSVLEMEKRE 164
T + L KR+
Sbjct: 863 HTLTRNLDVQLLDTKRQ 879
Score = 27.7 bits (60), Expect = 7.2
Identities = 20/75 (26%), Positives = 38/75 (50%), Gaps = 6/75 (8%)
Query: 120 QKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSV---LEMEKRERRALERKMSEME 176
++LKT + A + S E + ++KQ R ++ L+ + LE+K+ E+E
Sbjct: 953 ERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVE 1012
Query: 177 EEMKVLTELKSDNQR 191
+E + EL+ D +R
Sbjct: 1013 KEKQ---ELQDDKRR 1024
>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
sapiens]
Length = 820
Score = 49.7 bits (117), Expect = 2e-06
Identities = 49/194 (25%), Positives = 78/194 (40%), Gaps = 23/194 (11%)
Query: 4 NENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLSRL 63
+ + D D +SS R+R R ++RRRG ++ + +E H+ R
Sbjct: 27 DRERDRDRDRKSSPSKD-RKRHRSRDRRRGG-----SRSRSRSRSKSAERERRHKERERD 80
Query: 64 ESGGSNPTTSDSYGD---RASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQ 120
+ N D D R R R R SR + DS +D + E+
Sbjct: 81 KERDRNKKDRDRDKDGHRRDKDRKRSSLSPGRGKDFKSRKDRDSKKDEED-------EHG 133
Query: 121 KLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMK 180
K K Q LE K K E+ A+ K + L +RE AL+R+ E+EE +
Sbjct: 134 DKKPKAQPLSLEELLAKKKAEEEAEAKPK-------FLSKAEREAEALKRRQQEVEERQR 186
Query: 181 VLTELKSDNQRLKD 194
+L E + ++ +D
Sbjct: 187 MLEEERKKRKQFQD 200
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 48.1 bits (113), Expect = 5e-06
Identities = 38/222 (17%), Positives = 101/222 (45%), Gaps = 15/222 (6%)
Query: 1 MDKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERL 60
+++ +E+ + EQ KR E+ R +E+R+ W ++E + E+++E
Sbjct: 349 LEEKMHEQEKIREQEEKRQE-EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQ 407
Query: 61 SRLESGGSNPTT---SDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALT 117
+ E G + + RR+ + R R +E+ R+ +++ +
Sbjct: 408 EQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEE 467
Query: 118 ENQKLKTKLQEAQLELADIKSKL----------EKVAQQKQEKTSDRSSVLEMEKRERRA 167
+ + + K+ E + ++ + + K+ EK ++++EK ++ +++ ++ +
Sbjct: 468 KMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE 527
Query: 168 LERKMSEMEEEMKVLTE-LKSDNQRLKDENGALIRVISKLSK 208
E KM E EE+M+ E ++ ++++++ L + K+ +
Sbjct: 528 QEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 38.1 bits (87), Expect = 0.005
Identities = 44/217 (20%), Positives = 94/217 (43%), Gaps = 36/217 (16%)
Query: 2 DKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLS 61
+K + E + EQ K E+ R +E W K+E + EE+ E++
Sbjct: 295 EKIQEREEKIQEQEEKIREQEEKMRRQEEM------MWEKEE-KMRRQEEMMWEKEEKIR 347
Query: 62 RLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYES-ALTENQ 120
LE + ++ R + E R+ EE+ R+ +K E A Q
Sbjct: 348 ELE---------EKMHEQEKIREQEEKRQ----------EEEKIREQEKRQEQEAKMWRQ 388
Query: 121 KLKTKLQEAQLELAD--IKSKLEKVAQQKQEKTSDRSSVLEMEKRERRA------LERKM 172
+ K + QE ++ + ++ + EK+ +Q+++ + E E++ RR E+K+
Sbjct: 389 EEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKI 448
Query: 173 SEMEEEMKVLTE-LKSDNQRLKDENGALIRVISKLSK 208
E EE+++ E ++ +++ ++ G + +K+ +
Sbjct: 449 REQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQE 485
Score = 34.3 bits (77), Expect = 0.077
Identities = 25/103 (24%), Positives = 55/103 (53%), Gaps = 8/103 (7%)
Query: 94 ATLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSD 153
A L ++VEE N + +L + + + + K+QE + ++ + + K+ ++QE+
Sbjct: 267 AKLQAQVEE--NELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKI-----REQEEKMR 319
Query: 154 RSSVLEMEKRER-RALERKMSEMEEEMKVLTELKSDNQRLKDE 195
R + EK E+ R E M E EE+++ L E + ++++++
Sbjct: 320 RQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ 362
Score = 29.6 bits (65), Expect = 1.9
Identities = 23/106 (21%), Positives = 50/106 (47%), Gaps = 8/106 (7%)
Query: 85 RREAREARLATLTSRVEEDSNRDYKKLYE-----SALTENQKLKTKLQEAQLELADIKSK 139
+R+ A+L +++ +++ K+L A E +L +L + Q E +
Sbjct: 236 KRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKM---WR 292
Query: 140 LEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKVLTEL 185
E+ Q+++EK ++ + ++ + R E M E EE+M+ E+
Sbjct: 293 QEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEM 338
>gi|17865632 mitochondrial tumor suppressor 1 isoform 5 [Homo
sapiens]
Length = 436
Score = 47.8 bits (112), Expect = 7e-06
Identities = 36/119 (30%), Positives = 66/119 (55%), Gaps = 10/119 (8%)
Query: 87 EAREARLATLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEA--QLELADIKSKLEKVA 144
+ +A +R++E R+Y+KL ++ + E +K K +LQE L A SKLE A
Sbjct: 160 QQHQAEKTERENRLKEFYTREYEKLRDTYIEEAEKYKMQLQEQFDNLNAAHETSKLEIEA 219
Query: 145 QQKQE----KTSDRSSVLEMEKR---ERRALERKMSEMEEEM-KVLTELKSDNQRLKDE 195
++ K + +S+ E++K E+++LE +SE +E + K + +LKS+N L ++
Sbjct: 220 SHSEKLELLKKAYEASLSEIKKGHEIEKKSLEDLLSEKQESLEKQINDLKSENDALNEK 278
Score = 33.9 bits (76), Expect = 0.10
Identities = 32/119 (26%), Positives = 63/119 (52%), Gaps = 8/119 (6%)
Query: 97 TSRVEEDSNRD-----YKKLYESALTENQKLKTKLQEAQLE--LADIKSKLEKVAQQKQE 149
TS++E +++ KK YE++L+E +K ++++ LE L++ + LEK +
Sbjct: 212 TSKLEIEASHSEKLELLKKAYEASLSEIKK-GHEIEKKSLEDLLSEKQESLEKQINDLKS 270
Query: 150 KTSDRSSVLEMEKRERRALERKMSEMEEEMKVLTELKSDNQRLKDENGALIRVISKLSK 208
+ + L+ E+++RRA E+ + + M + EL+S L+ +N L + KL K
Sbjct: 271 ENDALNEKLKSEEQKRRAREKANLKNPQIMYLEQELESLKAVLEIKNEKLHQQDIKLMK 329
Score = 30.0 bits (66), Expect = 1.5
Identities = 28/114 (24%), Positives = 52/114 (45%), Gaps = 4/114 (3%)
Query: 87 EAREARLATLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQL-ELADIKSKLEKVAQ 145
E + L L S +E + L N+KLK++ Q+ + E A++K+ +
Sbjct: 244 EIEKKSLEDLLSEKQESLEKQINDLKSENDALNEKLKSEEQKRRAREKANLKNPQIMYLE 303
Query: 146 QKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKVLTELKSDNQRLKDENGAL 199
Q+ E +VLE++ + + K+ +ME+ + T L +R + EN L
Sbjct: 304 QELESLK---AVLEIKNEKLHQQDIKLMKMEKLVDNNTALVDKLKRFQQENEEL 354
>gi|50348611 mitochondrial tumor suppressor 1 isoform 1 [Homo sapiens]
Length = 1270
Score = 47.8 bits (112), Expect = 7e-06
Identities = 36/119 (30%), Positives = 66/119 (55%), Gaps = 10/119 (8%)
Query: 87 EAREARLATLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEA--QLELADIKSKLEKVA 144
+ +A +R++E R+Y+KL ++ + E +K K +LQE L A SKLE A
Sbjct: 994 QQHQAEKTERENRLKEFYTREYEKLRDTYIEEAEKYKMQLQEQFDNLNAAHETSKLEIEA 1053
Query: 145 QQKQE----KTSDRSSVLEMEKR---ERRALERKMSEMEEEM-KVLTELKSDNQRLKDE 195
++ K + +S+ E++K E+++LE +SE +E + K + +LKS+N L ++
Sbjct: 1054 SHSEKLELLKKAYEASLSEIKKGHEIEKKSLEDLLSEKQESLEKQINDLKSENDALNEK 1112
Score = 33.9 bits (76), Expect = 0.10
Identities = 32/119 (26%), Positives = 63/119 (52%), Gaps = 8/119 (6%)
Query: 97 TSRVEEDSNRD-----YKKLYESALTENQKLKTKLQEAQLE--LADIKSKLEKVAQQKQE 149
TS++E +++ KK YE++L+E +K ++++ LE L++ + LEK +
Sbjct: 1046 TSKLEIEASHSEKLELLKKAYEASLSEIKK-GHEIEKKSLEDLLSEKQESLEKQINDLKS 1104
Query: 150 KTSDRSSVLEMEKRERRALERKMSEMEEEMKVLTELKSDNQRLKDENGALIRVISKLSK 208
+ + L+ E+++RRA E+ + + M + EL+S L+ +N L + KL K
Sbjct: 1105 ENDALNEKLKSEEQKRRAREKANLKNPQIMYLEQELESLKAVLEIKNEKLHQQDIKLMK 1163
Score = 30.0 bits (66), Expect = 1.5
Identities = 28/114 (24%), Positives = 52/114 (45%), Gaps = 4/114 (3%)
Query: 87 EAREARLATLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQL-ELADIKSKLEKVAQ 145
E + L L S +E + L N+KLK++ Q+ + E A++K+ +
Sbjct: 1078 EIEKKSLEDLLSEKQESLEKQINDLKSENDALNEKLKSEEQKRRAREKANLKNPQIMYLE 1137
Query: 146 QKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKVLTELKSDNQRLKDENGAL 199
Q+ E +VLE++ + + K+ +ME+ + T L +R + EN L
Sbjct: 1138 QELESLK---AVLEIKNEKLHQQDIKLMKMEKLVDNNTALVDKLKRFQQENEEL 1188
>gi|50348617 mitochondrial tumor suppressor 1 isoform 2 [Homo sapiens]
Length = 1216
Score = 47.8 bits (112), Expect = 7e-06
Identities = 36/119 (30%), Positives = 66/119 (55%), Gaps = 10/119 (8%)
Query: 87 EAREARLATLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEA--QLELADIKSKLEKVA 144
+ +A +R++E R+Y+KL ++ + E +K K +LQE L A SKLE A
Sbjct: 940 QQHQAEKTERENRLKEFYTREYEKLRDTYIEEAEKYKMQLQEQFDNLNAAHETSKLEIEA 999
Query: 145 QQKQE----KTSDRSSVLEMEKR---ERRALERKMSEMEEEM-KVLTELKSDNQRLKDE 195
++ K + +S+ E++K E+++LE +SE +E + K + +LKS+N L ++
Sbjct: 1000 SHSEKLELLKKAYEASLSEIKKGHEIEKKSLEDLLSEKQESLEKQINDLKSENDALNEK 1058
Score = 33.9 bits (76), Expect = 0.10
Identities = 32/119 (26%), Positives = 63/119 (52%), Gaps = 8/119 (6%)
Query: 97 TSRVEEDSNRD-----YKKLYESALTENQKLKTKLQEAQLE--LADIKSKLEKVAQQKQE 149
TS++E +++ KK YE++L+E +K ++++ LE L++ + LEK +
Sbjct: 992 TSKLEIEASHSEKLELLKKAYEASLSEIKK-GHEIEKKSLEDLLSEKQESLEKQINDLKS 1050
Query: 150 KTSDRSSVLEMEKRERRALERKMSEMEEEMKVLTELKSDNQRLKDENGALIRVISKLSK 208
+ + L+ E+++RRA E+ + + M + EL+S L+ +N L + KL K
Sbjct: 1051 ENDALNEKLKSEEQKRRAREKANLKNPQIMYLEQELESLKAVLEIKNEKLHQQDIKLMK 1109
Score = 30.0 bits (66), Expect = 1.5
Identities = 28/114 (24%), Positives = 52/114 (45%), Gaps = 4/114 (3%)
Query: 87 EAREARLATLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQL-ELADIKSKLEKVAQ 145
E + L L S +E + L N+KLK++ Q+ + E A++K+ +
Sbjct: 1024 EIEKKSLEDLLSEKQESLEKQINDLKSENDALNEKLKSEEQKRRAREKANLKNPQIMYLE 1083
Query: 146 QKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKVLTELKSDNQRLKDENGAL 199
Q+ E +VLE++ + + K+ +ME+ + T L +R + EN L
Sbjct: 1084 QELESLK---AVLEIKNEKLHQQDIKLMKMEKLVDNNTALVDKLKRFQQENEEL 1134
>gi|50348626 mitochondrial tumor suppressor 1 isoform 4 [Homo
sapiens]
Length = 517
Score = 47.8 bits (112), Expect = 7e-06
Identities = 36/119 (30%), Positives = 66/119 (55%), Gaps = 10/119 (8%)
Query: 87 EAREARLATLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEA--QLELADIKSKLEKVA 144
+ +A +R++E R+Y+KL ++ + E +K K +LQE L A SKLE A
Sbjct: 241 QQHQAEKTERENRLKEFYTREYEKLRDTYIEEAEKYKMQLQEQFDNLNAAHETSKLEIEA 300
Query: 145 QQKQE----KTSDRSSVLEMEKR---ERRALERKMSEMEEEM-KVLTELKSDNQRLKDE 195
++ K + +S+ E++K E+++LE +SE +E + K + +LKS+N L ++
Sbjct: 301 SHSEKLELLKKAYEASLSEIKKGHEIEKKSLEDLLSEKQESLEKQINDLKSENDALNEK 359
Score = 33.9 bits (76), Expect = 0.10
Identities = 32/119 (26%), Positives = 63/119 (52%), Gaps = 8/119 (6%)
Query: 97 TSRVEEDSNRD-----YKKLYESALTENQKLKTKLQEAQLE--LADIKSKLEKVAQQKQE 149
TS++E +++ KK YE++L+E +K ++++ LE L++ + LEK +
Sbjct: 293 TSKLEIEASHSEKLELLKKAYEASLSEIKK-GHEIEKKSLEDLLSEKQESLEKQINDLKS 351
Query: 150 KTSDRSSVLEMEKRERRALERKMSEMEEEMKVLTELKSDNQRLKDENGALIRVISKLSK 208
+ + L+ E+++RRA E+ + + M + EL+S L+ +N L + KL K
Sbjct: 352 ENDALNEKLKSEEQKRRAREKANLKNPQIMYLEQELESLKAVLEIKNEKLHQQDIKLMK 410
Score = 30.0 bits (66), Expect = 1.5
Identities = 28/114 (24%), Positives = 52/114 (45%), Gaps = 4/114 (3%)
Query: 87 EAREARLATLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQL-ELADIKSKLEKVAQ 145
E + L L S +E + L N+KLK++ Q+ + E A++K+ +
Sbjct: 325 EIEKKSLEDLLSEKQESLEKQINDLKSENDALNEKLKSEEQKRRAREKANLKNPQIMYLE 384
Query: 146 QKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKVLTELKSDNQRLKDENGAL 199
Q+ E +VLE++ + + K+ +ME+ + T L +R + EN L
Sbjct: 385 QELESLK---AVLEIKNEKLHQQDIKLMKMEKLVDNNTALVDKLKRFQQENEEL 435
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 47.4 bits (111), Expect = 9e-06
Identities = 40/203 (19%), Positives = 91/203 (44%), Gaps = 16/203 (7%)
Query: 1 MDKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERL 60
+++ +E+ + EQ KR E+ R +E+R+ W ++E + E+++E +
Sbjct: 382 LEEKMHEQEKIREQEEKRQE-EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMW 440
Query: 61 SRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQ 120
+ E + R+E E R +E+ R +K++E Q
Sbjct: 441 RQEEKIHEQEKIREE-------EKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQ 493
Query: 121 KLKTKLQEAQLELAD--IKSKLEKVAQQKQEKTSDRSSVLEMEKRER------RALERKM 172
+ K QE ++ + I+ + EK+ +Q+++ + E E++ R + E KM
Sbjct: 494 EEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKM 553
Query: 173 SEMEEEMKVLTELKSDNQRLKDE 195
E EE+M+ +++ ++++++
Sbjct: 554 GEQEEKMQEQEKMRRQEEKIREQ 576
Score = 39.7 bits (91), Expect = 0.002
Identities = 33/161 (20%), Positives = 72/161 (44%), Gaps = 13/161 (8%)
Query: 22 RERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLSRLESGGSNPTTSDSYGDRAS 81
+E+ +E+ R W ++E D E+++E E++ R E + ++
Sbjct: 481 KEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQ-EEKMWRQE---------EKIREQEE 530
Query: 82 ARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQL--ELADIKSK 139
+E + + EE +K+ E Q+ K + QE ++ + I+ +
Sbjct: 531 KIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQ 590
Query: 140 LEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMK 180
EK+ +Q +EK ++ +++ ++ + E KM E EE+M+
Sbjct: 591 EEKIWEQ-EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ 630
Score = 38.9 bits (89), Expect = 0.003
Identities = 39/197 (19%), Positives = 80/197 (40%), Gaps = 19/197 (9%)
Query: 2 DKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLS 61
+K + E + EQ K E+ R +E + + E++ EE+ E++
Sbjct: 307 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 366
Query: 62 RLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQK 121
RLE RE E R +E+ ++ +K+ E + Q+
Sbjct: 367 RLEEMMWE-----------KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 415
Query: 122 LKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEK---RERRALERKMSEMEEE 178
K QE + I+ + EK+ +Q+++ + E EK E+R + +M EE+
Sbjct: 416 AKMWRQEEK-----IREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEK 470
Query: 179 MKVLTELKSDNQRLKDE 195
++ E+ +++ ++
Sbjct: 471 IREQEEIWRQKEKMHEQ 487
Score = 37.4 bits (85), Expect = 0.009
Identities = 29/118 (24%), Positives = 59/118 (50%), Gaps = 3/118 (2%)
Query: 81 SARARREAREARLAT-LTSRVEEDSNRDYKKLYE-SALTENQKLKTKLQEAQLELADIKS 138
SA+ + + E L L + EE R +K+ E + Q+ K + QE ++ + K
Sbjct: 278 SAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKM 337
Query: 139 KLEKVAQQKQEKTSDRSSVLEMEKRER-RALERKMSEMEEEMKVLTELKSDNQRLKDE 195
+ ++ ++E+ R + EK E+ R LE M E EE+++ L E + ++++++
Sbjct: 338 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQ 395
Score = 33.9 bits (76), Expect = 0.10
Identities = 35/212 (16%), Positives = 87/212 (41%), Gaps = 31/212 (14%)
Query: 2 DKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDED--------ETDGSEEVK 53
+K + +EA + Q K E+ R +E++ W ++E E + +E +
Sbjct: 409 EKRQEQEAKMWRQEEKIREQEEKIREQEKK------MWRQEEKIHEQEKIREEEKRQEQE 462
Query: 54 ETWHERLSRLESGGSNPTTSDSYGDRASARARREA---REARLATLTSRVEEDSNRDYK- 109
E W + ++ + ++ R + E +E ++ ++ E + ++
Sbjct: 463 EMWRQE-EKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQ 521
Query: 110 -----------KLYESALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVL 158
+ E + E +++ + +E E + + EK+ +Q +EK ++ +
Sbjct: 522 EEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQ-EEKIREQEEKI 580
Query: 159 EMEKRERRALERKMSEMEEEMKVLTELKSDNQ 190
+K + R E K+ E EE+++ E+ + +
Sbjct: 581 REQKEKIREQEEKIWEQEEKIREQEEMMQEQE 612
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 47.4 bits (111), Expect = 9e-06
Identities = 41/196 (20%), Positives = 80/196 (40%), Gaps = 4/196 (2%)
Query: 2 DKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGS---EEVKETWHE 58
D+ + E D + ++ +ER R KER R T + +TDG E ++ E
Sbjct: 100 DREKERERQTDRERDRQRE-KERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKE 158
Query: 59 RLSRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTE 118
R + + T + +R + R+E RE ED + + + E
Sbjct: 159 RERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERET 218
Query: 119 NQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEE 178
+ + K Q + K++ E+ Q ++E+ S+R + + E+ R +R ++E
Sbjct: 219 ETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKE 278
Query: 179 MKVLTELKSDNQRLKD 194
+ T+ K + +D
Sbjct: 279 RERQTDRKRQRRTERD 294
Score = 47.0 bits (110), Expect = 1e-05
Identities = 47/192 (24%), Positives = 80/192 (41%), Gaps = 14/192 (7%)
Query: 2 DKNENEEADLDEQSSK-RLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERL 60
D+ E + ++Q+ + R S RE R KER R + +D D E ++T +R
Sbjct: 233 DRQRKTEREREKQAERERASERETERDKERERERDRD---RDRDRRQKERE-RQTDRKRQ 288
Query: 61 SRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEE-DSNRDYKKLYESALTEN 119
R E + +R R R RE R + ++ RD +K E
Sbjct: 289 RRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERE----RK 344
Query: 120 QKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEM 179
+K +T++ + + + + ++++E+ DR S E E+RER + E E +
Sbjct: 345 RKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQ- 403
Query: 180 KVLTELKSDNQR 191
TE D QR
Sbjct: 404 ---TEKDRDGQR 412
Score = 43.1 bits (100), Expect = 2e-04
Identities = 48/193 (24%), Positives = 80/193 (41%), Gaps = 17/193 (8%)
Query: 3 KNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLSR 62
+ E E + +R R+R KER R T + E E ++ ER R
Sbjct: 132 EREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRER 191
Query: 63 LESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEE-DSNRDYKKLYESALTENQK 121
T DR S R R RE T T R + D RD ++ TE ++
Sbjct: 192 ERQREKENKTE----DRHSERGRERERERETETETERKRQTDRERDRQR-----KTERER 242
Query: 122 LKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKV 181
K +A+ E A + + E+ ++++E+ DR ++RER+ ++ E + +
Sbjct: 243 EK----QAERERAS-ERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRE- 296
Query: 182 LTELKSDNQRLKD 194
TE K + QR ++
Sbjct: 297 -TERKRERQRERE 308
Score = 42.7 bits (99), Expect = 2e-04
Identities = 45/211 (21%), Positives = 88/211 (41%), Gaps = 26/211 (12%)
Query: 2 DKNENEEADLDEQSSK-RLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERL 60
D+ + + + Q + R R+ RR +ER+R +++ E SE +E ER
Sbjct: 164 DRERQRQTERNRQKEREREKNRQERRERERQREK------ENKTEDRHSERGRERERERE 217
Query: 61 SRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQ 120
+ E+ T + R + R R + E A+ E ++ RD ++ E ++
Sbjct: 218 TETETERKRQTDRERDRQRKTEREREKQAERERAS-----ERETERDKERERERDRDRDR 272
Query: 121 KLKTKLQEAQLELA-------DIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMS 173
+ K +E Q + D +++ ++ Q+++E+ +R+ E E+ R ER+
Sbjct: 273 DRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRE 332
Query: 174 -------EMEEEMKVLTELKSDNQRLKDENG 197
E E + K TE+ + R G
Sbjct: 333 TERDREKERERKRKRQTEMDRERNRQTGREG 363
Score = 42.0 bits (97), Expect = 4e-04
Identities = 46/200 (23%), Positives = 81/200 (40%), Gaps = 23/200 (11%)
Query: 6 NEEADLDEQSSKRLSIRERRRPK-----------ERRRGTGINFWTKDEDETDGSEEVKE 54
+++AD D++ R RERRR K ERRR KD ++
Sbjct: 46 HKDADGDDRERNRQKERERRREKRQTERETDRKRERRR-------EKDRHRKRDRHRERQ 98
Query: 55 TWHERLSRLESGGSNPTTSDSYGDRASARAR---REAREARLATLTSRVEEDSNRDYKKL 111
E+ ++ + +R R R RE R + E + RD +K
Sbjct: 99 RDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKE 158
Query: 112 YESALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERK 171
E T+ ++ + + Q E K++ E+ +++Q + +++ E+ R ER+
Sbjct: 159 RERQ-TDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERE 217
Query: 172 MSEMEEEMKVLTELKSDNQR 191
+E E E K T+ + D QR
Sbjct: 218 -TETETERKRQTDRERDRQR 236
Score = 40.4 bits (93), Expect = 0.001
Identities = 36/163 (22%), Positives = 73/163 (44%), Gaps = 11/163 (6%)
Query: 13 EQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLSRLESGGSNPTT 72
E++ KR RER R +ER+R T +D ++ + ++T +R ++G
Sbjct: 312 ERNRKRERERERERERERQRET-----ERDREKERERKRKRQTEMDRERNRQTGREGRRQ 366
Query: 73 SDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQLE 132
++ +R R R+ ARE E D +RD +K E +++ + + ++ +
Sbjct: 367 AERERERERERDRQSARERE------ERERDRDRDRQKERERQTEKDRDGQRETEKQRER 420
Query: 133 LADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEM 175
D +S+ + +++EK R E + + +RK S +
Sbjct: 421 EKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTL 463
Score = 37.4 bits (85), Expect = 0.009
Identities = 45/215 (20%), Positives = 80/215 (37%), Gaps = 21/215 (9%)
Query: 2 DKNENEEADLDEQSSK------RLSIRERRRPKERRRGTGINFWTKDEDETDGS-----E 50
+KN E + + Q K R S R R R +ER T + + E D E
Sbjct: 182 EKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTERE 241
Query: 51 EVKETWHERLSRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKK 110
K+ ER S E+ + DR R ++E R E D + K+
Sbjct: 242 REKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKR 301
Query: 111 LYE---------SALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEME 161
+ + E ++ + + +E Q E + K E+ ++K++ DR +
Sbjct: 302 ERQRERERERERNRKRERERERERERERQRETERDREK-ERERKRKRQTEMDRERNRQTG 360
Query: 162 KRERRALERKMSEMEEEMKVLTELKSDNQRLKDEN 196
+ RR ER+ E + + + +R +D +
Sbjct: 361 REGRRQAERERERERERDRQSAREREERERDRDRD 395
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 47.4 bits (111), Expect = 9e-06
Identities = 29/103 (28%), Positives = 54/103 (52%), Gaps = 7/103 (6%)
Query: 87 EAREARLATLTS----RVEEDSNRDYKKLYESALTENQKLKTKLQEAQLEL---ADIKSK 139
EA ++RL + R+ E+ RDY++ + ALT+ Q L+ L++ + EL + +K
Sbjct: 999 EAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDD 1058
Query: 140 LEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKVL 182
++ +Q ++K S LE E+ L ++S E+M+ L
Sbjct: 1059 RSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQL 1101
Score = 39.3 bits (90), Expect = 0.002
Identities = 31/129 (24%), Positives = 60/129 (46%), Gaps = 11/129 (8%)
Query: 78 DRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQLELADI- 136
+ A + +E + + + E + ++L E L +++ Q E+ADI
Sbjct: 902 EAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIV 961
Query: 137 ----KSKLEKVAQQKQEKTSDRSSVLEMEKR-ERRALERKMS-----EMEEEMKVLTELK 186
S LE Q + K +R + EM+++ + + LE + S +M++EM+++ E
Sbjct: 962 EASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEEL 1021
Query: 187 SDNQRLKDE 195
D QR +DE
Sbjct: 1022 RDYQRAQDE 1030
Score = 33.1 bits (74), Expect = 0.17
Identities = 28/94 (29%), Positives = 46/94 (48%), Gaps = 17/94 (18%)
Query: 107 DYKKLYESALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERR 166
+ + + + EN L+ +L+E++ EL + LE++ Q K E+ E + E R
Sbjct: 653 ELRSQHNEKVEENSTLQQRLEESEGEL---RKNLEELFQVKMER--------EQHQTEIR 701
Query: 167 ALERKMSEMEEEMKVLTELKSDNQRLKDENGALI 200
L+ ++SEM +E L K R E GALI
Sbjct: 702 DLQDQLSEMHDE---LDSAKRSEDR---EKGALI 729
Score = 33.1 bits (74), Expect = 0.17
Identities = 48/200 (24%), Positives = 90/200 (45%), Gaps = 21/200 (10%)
Query: 7 EEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLSRLESG 66
EE D Q ++ ++ +R+ ++ + K + D S VK+ +++S+LE
Sbjct: 1018 EEELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQM-EDKVSQLEME 1076
Query: 67 -GSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQKLKTK 125
SD +R S R+R + + R L R + +D + S +N+ LK++
Sbjct: 1077 LEEERNNSDLLSERIS-RSREQMEQLRNELLQERA---ARQDLECDKISLERQNKDLKSR 1132
Query: 126 LQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRER-------RALERKMSEM--- 175
+ + +S E + Q + + ++ LE E+R+R R LERK+ E+
Sbjct: 1133 IIHLE---GSYRSSKEGLVVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQ 1189
Query: 176 -EEEMKVLTELKSD-NQRLK 193
++E LT+ K + RLK
Sbjct: 1190 VDDEHLSLTDQKDQLSLRLK 1209
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 47.0 bits (110), Expect = 1e-05
Identities = 41/194 (21%), Positives = 79/194 (40%), Gaps = 16/194 (8%)
Query: 3 KNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLSR 62
K E E E+ + RER + ++R RG K E + + +E +E R +
Sbjct: 52 KKERESERKKERREREKRKREREKERKRERG-------KKEKKGERKKEERERKKRRREK 104
Query: 63 LESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQKL 122
G + R +E +E +E+ R+ +K E E +K
Sbjct: 105 ENKEGEEKEKRKKKEKKERGRTSKEGKERER-------KEERKREERKERERKKEEREKE 157
Query: 123 KTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKVL 182
+ + + + E + K E+ ++++++ R + K+ER ER+ E ++E K
Sbjct: 158 RERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERR--ERKKERKKK 215
Query: 183 TELKSDNQRLKDEN 196
E K + Q+ + N
Sbjct: 216 EERKKERQKDRQTN 229
Score = 39.7 bits (91), Expect = 0.002
Identities = 38/162 (23%), Positives = 71/162 (43%), Gaps = 9/162 (5%)
Query: 13 EQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDG--SEEVKETWHERLSRLESGGSNP 70
E+ + ++RRR KE + G K E + G S+E KE + + E
Sbjct: 89 ERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERE 148
Query: 71 TTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQ 130
+ +R R R+E ++ + + EE ++ K E E + + K + +
Sbjct: 149 RKKE---EREKERERKERKKRERKQVGEKEEERKEKERK---ERKKRERNRKERKKERER 202
Query: 131 LELADIKSKLEKVAQQKQEKTSDR-SSVLEMEKRERRALERK 171
E + K + +K ++K+E+ DR ++ E E+ +R ERK
Sbjct: 203 KERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERK 244
Score = 35.0 bits (79), Expect = 0.045
Identities = 29/129 (22%), Positives = 59/129 (45%), Gaps = 5/129 (3%)
Query: 71 TTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQ 130
T + +R S R ++E RE E R K+ E ++ K + +E +
Sbjct: 47 TRKEGKKERESER-KKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKE 105
Query: 131 LELADIKSKLEKVAQQKQEKTS----DRSSVLEMEKRERRALERKMSEMEEEMKVLTELK 186
+ + K K +K ++++ +TS +R E ++ ER+ ERK E E+E + K
Sbjct: 106 NKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKK 165
Query: 187 SDNQRLKDE 195
+ +++ ++
Sbjct: 166 RERKQVGEK 174
Score = 28.9 bits (63), Expect = 3.2
Identities = 38/160 (23%), Positives = 67/160 (41%), Gaps = 33/160 (20%)
Query: 21 IRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLSRLESGGSNPTTSDSYGDRA 80
IRER R E R+ K E E++ +E +E + R + + G+R
Sbjct: 38 IREREREIETRKEG------KKERESERKKERREREKRKREREKERKRERGKKEKKGER- 90
Query: 81 SARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQLELADIKSKL 140
++E RE + R E N++ ++ E +K K K + + SK
Sbjct: 91 ----KKEERERK-----KRRREKENKEGEE------KEKRKKKEKKERGRT------SKE 129
Query: 141 EKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMK 180
K ++K+E+ + E ++RER+ ER+ +E K
Sbjct: 130 GKERERKEERKRE-----ERKERERKKEEREKERERKERK 164
Score = 28.1 bits (61), Expect = 5.5
Identities = 16/51 (31%), Positives = 29/51 (56%), Gaps = 7/51 (13%)
Query: 130 QLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMK 180
Q E+ + + ++E + K+E+ S+R K+ERR E++ E E+E K
Sbjct: 35 QSEIREREREIETRKEGKKERESER-------KKERREREKRKREREKERK 78
>gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens]
Length = 284
Score = 47.0 bits (110), Expect = 1e-05
Identities = 61/207 (29%), Positives = 97/207 (46%), Gaps = 39/207 (18%)
Query: 1 MDKNENEEADLD--EQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHE 58
+D+ E EAD E SK+L E +++ +GT EDE D E + E
Sbjct: 19 LDRAEQAEADKKAAEDRSKQLE-DELVSLQKKLKGT--------EDELDKYSEALKDAQE 69
Query: 59 RLSRLESGGSNPTTSDSYGDRASARARREAREA-------RLATLTSRVEE------DSN 105
+L E +D+ D AS R + E RLAT ++EE +S
Sbjct: 70 KLELAEK-----KATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESE 124
Query: 106 RDYKKLYESALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLE--MEKR 163
R K + A + +K++ +QE QL+ A + + A +K E+ + + ++E +E+
Sbjct: 125 RGMKVIESRAQKDEEKME--IQEIQLKEA---KHIAEDADRKYEEVARKLVIIESDLERA 179
Query: 164 ERRA--LERKMSEMEEEMKVLT-ELKS 187
E RA E K +E+EEE+K +T LKS
Sbjct: 180 EERAELSEGKCAELEEELKTVTNNLKS 206
Score = 28.1 bits (61), Expect = 5.5
Identities = 26/126 (20%), Positives = 56/126 (44%), Gaps = 9/126 (7%)
Query: 78 DRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQLELADIK 137
D+ +A R E EA + ED + K+L + ++ +KLK E +K
Sbjct: 14 DKENALDRAEQAEA-----DKKAAEDRS---KQLEDELVSLQKKLKGTEDELDKYSEALK 65
Query: 138 SKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKVLTELKSDNQRLKDENG 197
EK+ +++ T + V + +R + +E ++ +E + + + ++ DE+
Sbjct: 66 DAQEKLELAEKKATDAEADVASLNRR-IQLVEEELDRAQERLATALQKLEEAEKAADESE 124
Query: 198 ALIRVI 203
++VI
Sbjct: 125 RGMKVI 130
>gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens]
Length = 284
Score = 47.0 bits (110), Expect = 1e-05
Identities = 61/207 (29%), Positives = 97/207 (46%), Gaps = 39/207 (18%)
Query: 1 MDKNENEEADLD--EQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHE 58
+D+ E EAD E SK+L E +++ +GT EDE D E + E
Sbjct: 19 LDRAEQAEADKKAAEDRSKQLE-DELVSLQKKLKGT--------EDELDKYSEALKDAQE 69
Query: 59 RLSRLESGGSNPTTSDSYGDRASARARREAREA-------RLATLTSRVEE------DSN 105
+L E +D+ D AS R + E RLAT ++EE +S
Sbjct: 70 KLELAEK-----KATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESE 124
Query: 106 RDYKKLYESALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLE--MEKR 163
R K + A + +K++ +QE QL+ A + + A +K E+ + + ++E +E+
Sbjct: 125 RGMKVIESRAQKDEEKME--IQEIQLKEA---KHIAEDADRKYEEVARKLVIIESDLERA 179
Query: 164 ERRA--LERKMSEMEEEMKVLT-ELKS 187
E RA E K +E+EEE+K +T LKS
Sbjct: 180 EERAELSEGKCAELEEELKTVTNNLKS 206
Score = 28.1 bits (61), Expect = 5.5
Identities = 26/126 (20%), Positives = 56/126 (44%), Gaps = 9/126 (7%)
Query: 78 DRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQLELADIK 137
D+ +A R E EA + ED + K+L + ++ +KLK E +K
Sbjct: 14 DKENALDRAEQAEA-----DKKAAEDRS---KQLEDELVSLQKKLKGTEDELDKYSEALK 65
Query: 138 SKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKVLTELKSDNQRLKDENG 197
EK+ +++ T + V + +R + +E ++ +E + + + ++ DE+
Sbjct: 66 DAQEKLELAEKKATDAEADVASLNRR-IQLVEEELDRAQERLATALQKLEEAEKAADESE 124
Query: 198 ALIRVI 203
++VI
Sbjct: 125 RGMKVI 130
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.304 0.121 0.308
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,892,530
Number of Sequences: 37866
Number of extensions: 306942
Number of successful extensions: 6063
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 451
Number of HSP's successfully gapped in prelim test: 738
Number of HSP's that attempted gapping in prelim test: 2500
Number of HSP's gapped (non-prelim): 3255
length of query: 208
length of database: 18,247,518
effective HSP length: 98
effective length of query: 110
effective length of database: 14,536,650
effective search space: 1599031500
effective search space used: 1599031500
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.