Search of human proteins with 14165422

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo
sapiens]
         (814 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo sapi...  1610   0.0  
gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens]  1574   0.0  
gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo sapi...  1387   0.0  
gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens]  1382   0.0  
gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo sapi...  1239   0.0  
gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens]  1234   0.0  
gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens]  1227   0.0  
gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapi...  1227   0.0  
gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo sap...  1222   0.0  
gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo sapi...  1222   0.0  
gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo sapi...  1219   0.0  
gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens]  1215   0.0  
gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo sap...  1209   0.0  
gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo sapi...  1207   0.0  
gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo sapi...  1206   0.0  
gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens]  1206   0.0  
gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo sap...  1203   0.0  
gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo sapi...  1200   0.0  
gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo sapi...  1192   0.0  
gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens]  1192   0.0  
gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo sap...  1191   0.0  
gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo sapi...  1191   0.0  
gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens]  1185   0.0  
gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo sapi...  1184   0.0  
gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo sapi...  1179   0.0  
gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens]  1179   0.0  
gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo sapi...   942   0.0  
gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo sap...   804   0.0  
gi|14165402 protocadherin alpha 1 isoform 3 precursor [Homo sapi...   796   0.0  
gi|14277677 protocadherin gamma subfamily C, 3 isoform 2 precurs...   610   e-174

>gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo
           sapiens]
          Length = 814

 Score = 1610 bits (4168), Expect = 0.0
 Identities = 814/814 (100%), Positives = 814/814 (100%)

Query: 1   MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
           MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV
Sbjct: 1   MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD
Sbjct: 61  PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120

Query: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180
           VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML
Sbjct: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180

Query: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240
           DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP
Sbjct: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240

Query: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300
           TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG
Sbjct: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300

Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360
           EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR
Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360

Query: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420
           EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA
Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420

Query: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480
           YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR
Sbjct: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA
Sbjct: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660

Query: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL 780
           LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL
Sbjct: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL 780

Query: 781 GSVDVGEEQDLNVDHGLKVSPFKFRTHKFYLWKL 814
           GSVDVGEEQDLNVDHGLKVSPFKFRTHKFYLWKL
Sbjct: 781 GSVDVGEEQDLNVDHGLKVSPFKFRTHKFYLWKL 814


>gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score = 1574 bits (4076), Expect = 0.0
 Identities = 798/798 (100%), Positives = 798/798 (100%)

Query: 1   MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
           MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV
Sbjct: 1   MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD
Sbjct: 61  PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120

Query: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180
           VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML
Sbjct: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180

Query: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240
           DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP
Sbjct: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240

Query: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300
           TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG
Sbjct: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300

Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360
           EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR
Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360

Query: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420
           EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA
Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420

Query: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480
           YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR
Sbjct: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA
Sbjct: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660

Query: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL 780
           LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL
Sbjct: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL 780

Query: 781 GSVDVGEEQDLNVDHGLK 798
           GSVDVGEEQDLNVDHGLK
Sbjct: 781 GSVDVGEEQDLNVDHGLK 798


>gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo
           sapiens]
          Length = 803

 Score = 1387 bits (3591), Expect = 0.0
 Identities = 710/794 (89%), Positives = 739/794 (93%)

Query: 9   LGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68
           LG   LLL LLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFR+AS
Sbjct: 9   LGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMAS 68

Query: 69  KRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVND 128
           K   DLLEV+LQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEV+D+ND
Sbjct: 69  KDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDIND 128

Query: 129 NPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDE 188
           NPP+F V++Q++ + ESR+PDS FPLEGASDADVG+NS+LTY+LSS +YF LDV   +D+
Sbjct: 129 NPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDD 188

Query: 189 NKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248
           NK + L+L+KSLDRE+APAH+LFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE
Sbjct: 189 NKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248

Query: 249 VRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNL 308
           VRIFENADNGTTVI+LNASD DEGANGAISYSFNSLV  MVIDHFSIDRNTGEIVIRGNL
Sbjct: 249 VRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNL 308

Query: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368
           DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV
Sbjct: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368

Query: 369 IALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTAR 428
           IALISVNDLDSGANGQV CSL PHVPFKLVSTFKNYYSLVLDSALDRE VSAYELVVTAR
Sbjct: 369 IALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTAR 428

Query: 429 DGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488
           DGGSPSLWATASLSVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA
Sbjct: 429 DGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488

Query: 489 LVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548
           LVSYSLVERRVGER+LSSYISVH ESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN
Sbjct: 489 LVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548

Query: 549 VTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLS 608
           VTLQVFVLDENDNAPALL PRVGGTGGA S+LVPRS+GAG VVAKVRAVDADSGYNAWLS
Sbjct: 549 VTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLS 608

Query: 609 YELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS 668
           YELQP ASS R PFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS
Sbjct: 609 YELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS 668

Query: 669 LVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPT 728
           LVESGQAPKASSR S G  GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA PT
Sbjct: 669 LVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728

Query: 729 EGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVDVGEE 788
           EG C A KPTLVCSSAVGSWSYSQQ+ QRVCSGEGPPK DLMAFSP L P    +   E 
Sbjct: 729 EGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAEN 788

Query: 789 QDLNVDHGLKVSPF 802
           QDLN DH  KVS F
Sbjct: 789 QDLNEDHDAKVSEF 802


>gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score = 1382 bits (3578), Expect = 0.0
 Identities = 707/790 (89%), Positives = 736/790 (93%)

Query: 9   LGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68
           LG   LLL LLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFR+AS
Sbjct: 9   LGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMAS 68

Query: 69  KRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVND 128
           K   DLLEV+LQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEV+D+ND
Sbjct: 69  KDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDIND 128

Query: 129 NPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDE 188
           NPP+F V++Q++ + ESR+PDS FPLEGASDADVG+NS+LTY+LSS +YF LDV   +D+
Sbjct: 129 NPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDD 188

Query: 189 NKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248
           NK + L+L+KSLDRE+APAH+LFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE
Sbjct: 189 NKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248

Query: 249 VRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNL 308
           VRIFENADNGTTVI+LNASD DEGANGAISYSFNSLV  MVIDHFSIDRNTGEIVIRGNL
Sbjct: 249 VRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNL 308

Query: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368
           DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV
Sbjct: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368

Query: 369 IALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTAR 428
           IALISVNDLDSGANGQV CSL PHVPFKLVSTFKNYYSLVLDSALDRE VSAYELVVTAR
Sbjct: 369 IALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTAR 428

Query: 429 DGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488
           DGGSPSLWATASLSVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA
Sbjct: 429 DGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488

Query: 489 LVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548
           LVSYSLVERRVGER+LSSYISVH ESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN
Sbjct: 489 LVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548

Query: 549 VTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLS 608
           VTLQVFVLDENDNAPALL PRVGGTGGA S+LVPRS+GAG VVAKVRAVDADSGYNAWLS
Sbjct: 549 VTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLS 608

Query: 609 YELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS 668
           YELQP ASS R PFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS
Sbjct: 609 YELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS 668

Query: 669 LVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPT 728
           LVESGQAPKASSR S G  GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA PT
Sbjct: 669 LVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728

Query: 729 EGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVDVGEE 788
           EG C A KPTLVCSSAVGSWSYSQQ+ QRVCSGEGPPK DLMAFSP L P    +   E 
Sbjct: 729 EGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAEN 788

Query: 789 QDLNVDHGLK 798
           QDLN DH  K
Sbjct: 789 QDLNEDHDAK 798


>gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo
           sapiens]
          Length = 824

 Score = 1239 bits (3205), Expect = 0.0
 Identities = 632/802 (78%), Positives = 696/802 (86%)

Query: 1   MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
           M + WR + G+  LLL LLLLAA +VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV
Sbjct: 1   MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLFRVASKRH DLLEV+LQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+
Sbjct: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120

Query: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180
           VEVKD+NDN PVF +  + LF+SESR P SRF LEGASDAD+G NS+LTY L S +YF L
Sbjct: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180

Query: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240
           DV   ++E K + LVL+K+L+RED P H+L +TA DGGKPELTGT QL +TVLDVNDNAP
Sbjct: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240

Query: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300
            FE++ Y+VR+ ENA NGT V+ +NA+D DEG N  I+YSFN+ +   ++  F +D   G
Sbjct: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300

Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360
           +I ++GN+DFE+   Y+I ++ATDKG+PPM+ HCTVL+ I+D NDNVPE+ + SLSLPV 
Sbjct: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360

Query: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420
           ED+   TVIALISV+D DSG NGQVTCSL PHVPFKLVSTFKNYYSLVLDS LDRE VSA
Sbjct: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480
           YELVVTARDGGSPSLWATAS+SVEVADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSAR
Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQENALVSYSLVERRVGER+LSSY+SVH ESGKVYALQPLDHEELELLQFQVSARDA
Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL PRVGG GGA S+LVPRSVGAGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQP     RIPFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEP+LT
Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660

Query: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVLVSLVESGQAPKASS+ SAG  GPEAALVDVNVYLI+AICAVSSLLVLTLLLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL 780
           LRCSA PTEG C  GKPTLVCSSAVGSWSYSQQ+ QRVCSGEG PKTDLMAFSP LPP  
Sbjct: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780

Query: 781 GSVDVGEEQDLNVDHGLKVSPF 802
            S D  E+QD++VD   KVS F
Sbjct: 781 ISRDREEKQDVDVDLSAKVSNF 802


>gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score = 1234 bits (3193), Expect = 0.0
 Identities = 629/798 (78%), Positives = 693/798 (86%)

Query: 1   MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
           M + WR + G+  LLL LLLLAA +VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV
Sbjct: 1   MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLFRVASKRH DLLEV+LQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+
Sbjct: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120

Query: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180
           VEVKD+NDN PVF +  + LF+SESR P SRF LEGASDAD+G NS+LTY L S +YF L
Sbjct: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180

Query: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240
           DV   ++E K + LVL+K+L+RED P H+L +TA DGGKPELTGT QL +TVLDVNDNAP
Sbjct: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240

Query: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300
            FE++ Y+VR+ ENA NGT V+ +NA+D DEG N  I+YSFN+ +   ++  F +D   G
Sbjct: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300

Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360
           +I ++GN+DFE+   Y+I ++ATDKG+PPM+ HCTVL+ I+D NDNVPE+ + SLSLPV 
Sbjct: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360

Query: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420
           ED+   TVIALISV+D DSG NGQVTCSL PHVPFKLVSTFKNYYSLVLDS LDRE VSA
Sbjct: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480
           YELVVTARDGGSPSLWATAS+SVEVADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSAR
Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQENALVSYSLVERRVGER+LSSY+SVH ESGKVYALQPLDHEELELLQFQVSARDA
Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL PRVGG GGA S+LVPRSVGAGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQP     RIPFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEP+LT
Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660

Query: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVLVSLVESGQAPKASS+ SAG  GPEAALVDVNVYLI+AICAVSSLLVLTLLLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL 780
           LRCSA PTEG C  GKPTLVCSSAVGSWSYSQQ+ QRVCSGEG PKTDLMAFSP LPP  
Sbjct: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780

Query: 781 GSVDVGEEQDLNVDHGLK 798
            S D  E+QD++VD   K
Sbjct: 781 ISRDREEKQDVDVDLSAK 798


>gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens]
          Length = 936

 Score = 1227 bits (3175), Expect = 0.0
 Identities = 631/784 (80%), Positives = 680/784 (86%), Gaps = 1/784 (0%)

Query: 1   MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
           M Y  RG LGS RLLLL LLLA WK GSGQLHYS+PEEAKHGTFVGRIAQDLGLELAELV
Sbjct: 1   MVYSRRGSLGS-RLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59

Query: 61  PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLFRVASK   DLLEV+LQNGILFVNSRIDREELC R AECSIHLEVIVDRPLQVFHV+
Sbjct: 60  PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119

Query: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180
           V VKD+NDNPP F  ++Q+LF+ ESRMPDSRFPLEGASD D+GAN+ L YRL+ ++YF L
Sbjct: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179

Query: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240
           DV +  +E   +ELVLRKSLDRE+   H L + ATDGGKPELTGTVQLL+ VLD NDNAP
Sbjct: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239

Query: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300
            F++S Y VR+ ENA +GT VIKLNASD DEG N  I Y F++LV   V   F I+ NTG
Sbjct: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299

Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360
           EI + G LD+E  N Y+I IDA DK   P++GHC V+V++LD NDN PE+A+T+L LPV+
Sbjct: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359

Query: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420
           EDA   TVIALISV+D DSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRE VS 
Sbjct: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419

Query: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480
           YELVVTARDGGSPSLWATAS+SVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSAR
Sbjct: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479

Query: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQENALVSYSLVERRVGER LSSY+SVH ESGKVYALQPLDHEE+ELLQFQVSARDA
Sbjct: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL PRVGGTGGA S+LVPRSVGAGHVVAKVRAVD D
Sbjct: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599

Query: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQPA  S RIPFRVGLYTGEISTTR LDE ++PRHRLLVLVKDHGEP LT
Sbjct: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659

Query: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVLVSLVESGQAPKASSR SAG +GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719

Query: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL 780
           LRCSA PTE  C  GKPTL+CSSAVGSWSYSQQ+ QRVCSGE PPKTDLMAFSP LP   
Sbjct: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGP 779

Query: 781 GSVD 784
            S D
Sbjct: 780 TSTD 783


>gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo
           sapiens]
          Length = 816

 Score = 1227 bits (3175), Expect = 0.0
 Identities = 631/784 (80%), Positives = 680/784 (86%), Gaps = 1/784 (0%)

Query: 1   MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
           M Y  RG LGS RLLLL LLLA WK GSGQLHYS+PEEAKHGTFVGRIAQDLGLELAELV
Sbjct: 1   MVYSRRGSLGS-RLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59

Query: 61  PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLFRVASK   DLLEV+LQNGILFVNSRIDREELC R AECSIHLEVIVDRPLQVFHV+
Sbjct: 60  PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119

Query: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180
           V VKD+NDNPP F  ++Q+LF+ ESRMPDSRFPLEGASD D+GAN+ L YRL+ ++YF L
Sbjct: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179

Query: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240
           DV +  +E   +ELVLRKSLDRE+   H L + ATDGGKPELTGTVQLL+ VLD NDNAP
Sbjct: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239

Query: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300
            F++S Y VR+ ENA +GT VIKLNASD DEG N  I Y F++LV   V   F I+ NTG
Sbjct: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299

Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360
           EI + G LD+E  N Y+I IDA DK   P++GHC V+V++LD NDN PE+A+T+L LPV+
Sbjct: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359

Query: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420
           EDA   TVIALISV+D DSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRE VS 
Sbjct: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419

Query: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480
           YELVVTARDGGSPSLWATAS+SVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSAR
Sbjct: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479

Query: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQENALVSYSLVERRVGER LSSY+SVH ESGKVYALQPLDHEE+ELLQFQVSARDA
Sbjct: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL PRVGGTGGA S+LVPRSVGAGHVVAKVRAVD D
Sbjct: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599

Query: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQPA  S RIPFRVGLYTGEISTTR LDE ++PRHRLLVLVKDHGEP LT
Sbjct: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659

Query: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVLVSLVESGQAPKASSR SAG +GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719

Query: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL 780
           LRCSA PTE  C  GKPTL+CSSAVGSWSYSQQ+ QRVCSGE PPKTDLMAFSP LP   
Sbjct: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGP 779

Query: 781 GSVD 784
            S D
Sbjct: 780 TSTD 783


>gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo
           sapiens]
          Length = 807

 Score = 1222 bits (3162), Expect = 0.0
 Identities = 615/780 (78%), Positives = 681/780 (87%)

Query: 5   WRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLF 64
           W+G     +LLL LL+LAAW+ GSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLF
Sbjct: 5   WQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLF 64

Query: 65  RVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVK 124
           RVASKRH DLLEV+LQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+V+V+
Sbjct: 65  RVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVR 124

Query: 125 DVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNS 184
           D+NDNPP+F    +++ ++ESR P++RFPL+GASDAD+G NS LTYRL  +DYF LD  +
Sbjct: 125 DINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQN 184

Query: 185 KNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQ 244
             ++   + LVLRK+LDRE+   H L LTA+DGGKPELTGTVQLL+T+LDVNDNAP F Q
Sbjct: 185 SLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQ 244

Query: 245 SEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVI 304
           S Y+V + ENA NGT VIKLNA+DPD+G NG I YSF   V   V+  F+I+ N GEI  
Sbjct: 245 SVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRT 304

Query: 305 RGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQ 364
           +G LDFE++ LY+I ++A DKG+ PMAGHCT+LV +LD NDN PE+ +TSLSLP+RED Q
Sbjct: 305 KGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQ 364

Query: 365 FGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELV 424
              +IALISV+D DSG+NGQVTC+L PHVPFKLVST+KNYYSLVLDSALDRE VSAYELV
Sbjct: 365 PSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELV 424

Query: 425 VTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADA 484
           VTARDGGSPSLWATAS+SV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA+DADA
Sbjct: 425 VTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADA 484

Query: 485 QENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPP 544
           QENALVSYSLVERRVGER+LSSY+SVH ESGKVYALQPLDHEELELLQFQVSARD+GVPP
Sbjct: 485 QENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPP 544

Query: 545 LGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYN 604
           LGSNVTLQVFVLDENDNAPALL P  G  GG  S+L+PRSVGAGHVVAKVRAVDADSGYN
Sbjct: 545 LGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYN 604

Query: 605 AWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATAT 664
           AWLSYELQ AA   RIPFRVGLYTGEISTTR LDE D+P HRLLVLVKDHGEPALTATAT
Sbjct: 605 AWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATAT 664

Query: 665 VLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCS 724
           VL+SLVESGQAP+ASSR SAG +GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCS
Sbjct: 665 VLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCS 724

Query: 725 ALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVD 784
           A PTEG C  GKPTLVCSSA GSWSYSQQ+  RVCSGEGP KTDLMAFSP LPP LGS +
Sbjct: 725 APPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCLGSAE 784


>gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo
           sapiens]
          Length = 950

 Score = 1222 bits (3162), Expect = 0.0
 Identities = 615/780 (78%), Positives = 681/780 (87%)

Query: 5   WRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLF 64
           W+G     +LLL LL+LAAW+ GSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLF
Sbjct: 5   WQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLF 64

Query: 65  RVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVK 124
           RVASKRH DLLEV+LQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+V+V+
Sbjct: 65  RVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVR 124

Query: 125 DVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNS 184
           D+NDNPP+F    +++ ++ESR P++RFPL+GASDAD+G NS LTYRL  +DYF LD  +
Sbjct: 125 DINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQN 184

Query: 185 KNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQ 244
             ++   + LVLRK+LDRE+   H L LTA+DGGKPELTGTVQLL+T+LDVNDNAP F Q
Sbjct: 185 SLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQ 244

Query: 245 SEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVI 304
           S Y+V + ENA NGT VIKLNA+DPD+G NG I YSF   V   V+  F+I+ N GEI  
Sbjct: 245 SVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRT 304

Query: 305 RGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQ 364
           +G LDFE++ LY+I ++A DKG+ PMAGHCT+LV +LD NDN PE+ +TSLSLP+RED Q
Sbjct: 305 KGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQ 364

Query: 365 FGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELV 424
              +IALISV+D DSG+NGQVTC+L PHVPFKLVST+KNYYSLVLDSALDRE VSAYELV
Sbjct: 365 PSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELV 424

Query: 425 VTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADA 484
           VTARDGGSPSLWATAS+SV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA+DADA
Sbjct: 425 VTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADA 484

Query: 485 QENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPP 544
           QENALVSYSLVERRVGER+LSSY+SVH ESGKVYALQPLDHEELELLQFQVSARD+GVPP
Sbjct: 485 QENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPP 544

Query: 545 LGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYN 604
           LGSNVTLQVFVLDENDNAPALL P  G  GG  S+L+PRSVGAGHVVAKVRAVDADSGYN
Sbjct: 545 LGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYN 604

Query: 605 AWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATAT 664
           AWLSYELQ AA   RIPFRVGLYTGEISTTR LDE D+P HRLLVLVKDHGEPALTATAT
Sbjct: 605 AWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATAT 664

Query: 665 VLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCS 724
           VL+SLVESGQAP+ASSR SAG +GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCS
Sbjct: 665 VLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCS 724

Query: 725 ALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVD 784
           A PTEG C  GKPTLVCSSA GSWSYSQQ+  RVCSGEGP KTDLMAFSP LPP LGS +
Sbjct: 725 APPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCLGSAE 784


>gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 807

 Score = 1219 bits (3153), Expect = 0.0
 Identities = 624/811 (76%), Positives = 694/811 (85%), Gaps = 4/811 (0%)

Query: 1   MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
           M +  RG LG+  LLL LLLLAAW+VGSGQLHYS+PEEAKHGTFVGR+AQDLGLELAELV
Sbjct: 1   MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60

Query: 61  PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLFRVASK HRDLLEV+LQNGILFVNSRIDREELC  SAECSIHLE+I DRPLQVFHV+
Sbjct: 61  PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120

Query: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180
           V+VKD+NDNPPVFR ++Q +F+ ESR+ +SRFP+EGA+DAD+GAN++LTY LS  DYF L
Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180

Query: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240
           DV + ++ +K + L LRK LDRE+ P  HL LTATDGGKPEL GTV+LL+TVLDVNDNAP
Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240

Query: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300
            F+Q+ Y V + E   NGT V  LNASD DEG NG + +SF+S +   + + F +D ++G
Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300

Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360
           EI +   LD+E+   Y+I + A DKG PPM+ HC VLV++LD NDN PE+A+TSL LP+R
Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360

Query: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420
           EDA   TVIALI+V+D DSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRE +S 
Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420

Query: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480
           YELVVTARDGGSPSLWATA +SVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR
Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQENALVSYSLVERRVGER+LS+Y+SVH ESGKVYALQPLDHEELELLQFQVSARDA
Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL PRVGGT GA S+LVPR VGAGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQPAA   RIPFRVGLYTGEISTTRVLDEAD  R+RLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT 660

Query: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVLVSLVESGQAPKASSR S GV GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL 780
           LRCS  PTEG    GKPTLVCSSA+GSWS SQQ+ QRVCS EGPPKTDLMAFSP L P L
Sbjct: 721 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL 780

Query: 781 GSVDVGEEQDLNVDHGLKVSPFKFRTHKFYL 811
            + +  E+ + N+D    VSP    T +F+L
Sbjct: 781 NTSERNEQPEANLDLSGNVSP----TFEFWL 807


>gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score = 1215 bits (3143), Expect = 0.0
 Identities = 618/794 (77%), Positives = 686/794 (86%)

Query: 1   MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
           M +  RG LG+  LLL LLLLAAW+VGSGQLHYS+PEEAKHGTFVGR+AQDLGLELAELV
Sbjct: 1   MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60

Query: 61  PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLFRVASK HRDLLEV+LQNGILFVNSRIDREELC  SAECSIHLE+I DRPLQVFHV+
Sbjct: 61  PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120

Query: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180
           V+VKD+NDNPPVFR ++Q +F+ ESR+ +SRFP+EGA+DAD+GAN++LTY LS  DYF L
Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180

Query: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240
           DV + ++ +K + L LRK LDRE+ P  HL LTATDGGKPEL GTV+LL+TVLDVNDNAP
Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240

Query: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300
            F+Q+ Y V + E   NGT V  LNASD DEG NG + +SF+S +   + + F +D ++G
Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300

Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360
           EI +   LD+E+   Y+I + A DKG PPM+ HC VLV++LD NDN PE+A+TSL LP+R
Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360

Query: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420
           EDA   TVIALI+V+D DSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRE +S 
Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420

Query: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480
           YELVVTARDGGSPSLWATA +SVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR
Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQENALVSYSLVERRVGER+LS+Y+SVH ESGKVYALQPLDHEELELLQFQVSARDA
Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL PRVGGT GA S+LVPR VGAGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQPAA   RIPFRVGLYTGEISTTRVLDEAD  R+RLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT 660

Query: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVLVSLVESGQAPKASSR S GV GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL 780
           LRCS  PTEG    GKPTLVCSSA+GSWS SQQ+ QRVCS EGPPKTDLMAFSP L P L
Sbjct: 721 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL 780

Query: 781 GSVDVGEEQDLNVD 794
            + +  E+ + N+D
Sbjct: 781 NTSERNEQPEANLD 794


>gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo
           sapiens]
          Length = 810

 Score = 1209 bits (3127), Expect = 0.0
 Identities = 623/795 (78%), Positives = 680/795 (85%), Gaps = 1/795 (0%)

Query: 6   RGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFR 65
           R  LG+ RL L LLLL  W+VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV RLFR
Sbjct: 6   RRGLGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFR 65

Query: 66  VASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKD 125
           VASK H DLLEV+LQNGILFVNSRIDREELCG+SAECSIHLEVIVDRPLQVFHV+VEVKD
Sbjct: 66  VASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKD 125

Query: 126 VNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSK 185
           +NDNPPVF +++QKL ++ES+  DSRFPLEGASDAD+  N++LTYRLS ++YF LD  + 
Sbjct: 126 INDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTN 185

Query: 186 NDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQS 245
             + K + L+L+KSLDRE  P  +L LTATDGGKPELTGTV+LLV VLDVNDN P F++S
Sbjct: 186 GKQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKS 245

Query: 246 EYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIR 305
           EY+V + ENA   T V+KLNA+D DEG NG ++YS  S ++      F++D+N GE+ + 
Sbjct: 246 EYKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVN 304

Query: 306 GNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQF 365
           G LD+E+   YKI + ATDKG PPMAGHCTV V ILD NDN PE+A+TSLSLPVREDAQ 
Sbjct: 305 GTLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQP 364

Query: 366 GTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVV 425
            TVIALISV+D DSG NGQVTCSL PHVPFKLVSTFKNYYSLVLDSALDRE V AYELVV
Sbjct: 365 STVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVV 424

Query: 426 TARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQ 485
           TARDGGSPSLWATA +SVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQ
Sbjct: 425 TARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQ 484

Query: 486 ENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPL 545
           ENALVSYSLVERR+G+R+LSSY+SVH ESGKVYALQPLDHEELELLQFQVSARDAGVPPL
Sbjct: 485 ENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL 544

Query: 546 GSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNA 605
            SNVTLQVFVLDENDNAPALL  + G  GGA +KLVPRSVGAGHVVAKVRAVDADSGYNA
Sbjct: 545 SSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNA 604

Query: 606 WLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATV 665
           WLSYELQPAA   RIPFRVGLYTGEISTTR LDEADSPRHRLLVLVKDHGEPALTATATV
Sbjct: 605 WLSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATV 664

Query: 666 LVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA 725
           LVSLVESGQAPKASSR  AG   PEAALVDVNVYLIIAIC VSSLLVLTLLLYTAL  SA
Sbjct: 665 LVSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSA 724

Query: 726 LPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVDV 785
            PTEG C  GKPTLVCS AVGSWSYSQQ+ QRVCS EGPPKTDLMAFSP LP  L   + 
Sbjct: 725 TPTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNKEEE 784

Query: 786 GEEQDLNVDHGLKVS 800
           GE Q+   +H  +VS
Sbjct: 785 GERQEPGSNHPGQVS 799


>gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo
           sapiens]
          Length = 949

 Score = 1207 bits (3124), Expect = 0.0
 Identities = 621/790 (78%), Positives = 677/790 (85%), Gaps = 1/790 (0%)

Query: 6   RGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFR 65
           R  LG+ RL L LLLL  W+VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV RLFR
Sbjct: 6   RRGLGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFR 65

Query: 66  VASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKD 125
           VASK H DLLEV+LQNGILFVNSRIDREELCG+SAECSIHLEVIVDRPLQVFHV+VEVKD
Sbjct: 66  VASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKD 125

Query: 126 VNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSK 185
           +NDNPPVF +++QKL ++ES+  DSRFPLEGASDAD+  N++LTYRLS ++YF LD  + 
Sbjct: 126 INDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTN 185

Query: 186 NDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQS 245
             + K + L+L+KSLDRE  P  +L LTATDGGKPELTGTV+LLV VLDVNDN P F++S
Sbjct: 186 GKQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKS 245

Query: 246 EYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIR 305
           EY+V + ENA   T V+KLNA+D DEG NG ++YS  S ++      F++D+N GE+ + 
Sbjct: 246 EYKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVN 304

Query: 306 GNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQF 365
           G LD+E+   YKI + ATDKG PPMAGHCTV V ILD NDN PE+A+TSLSLPVREDAQ 
Sbjct: 305 GTLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQP 364

Query: 366 GTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVV 425
            TVIALISV+D DSG NGQVTCSL PHVPFKLVSTFKNYYSLVLDSALDRE V AYELVV
Sbjct: 365 STVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVV 424

Query: 426 TARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQ 485
           TARDGGSPSLWATA +SVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQ
Sbjct: 425 TARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQ 484

Query: 486 ENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPL 545
           ENALVSYSLVERR+G+R+LSSY+SVH ESGKVYALQPLDHEELELLQFQVSARDAGVPPL
Sbjct: 485 ENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL 544

Query: 546 GSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNA 605
            SNVTLQVFVLDENDNAPALL  + G  GGA +KLVPRSVGAGHVVAKVRAVDADSGYNA
Sbjct: 545 SSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNA 604

Query: 606 WLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATV 665
           WLSYELQPAA   RIPFRVGLYTGEISTTR LDEADSPRHRLLVLVKDHGEPALTATATV
Sbjct: 605 WLSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATV 664

Query: 666 LVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA 725
           LVSLVESGQAPKASSR  AG   PEAALVDVNVYLIIAIC VSSLLVLTLLLYTAL  SA
Sbjct: 665 LVSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSA 724

Query: 726 LPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVDV 785
            PTEG C  GKPTLVCS AVGSWSYSQQ+ QRVCS EGPPKTDLMAFSP LP  L   + 
Sbjct: 725 TPTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNKEEE 784

Query: 786 GEEQDLNVDH 795
           GE Q+   +H
Sbjct: 785 GERQEPGSNH 794


>gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo
           sapiens]
          Length = 798

 Score = 1206 bits (3121), Expect = 0.0
 Identities = 614/777 (79%), Positives = 671/777 (86%)

Query: 1   MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
           M++ W     S RLLLLLLLLAAW+ G+GQLHYSV EEAKHGTFVGRIAQDLGLELAELV
Sbjct: 1   MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLFRVASK    LLEV+LQNGILFVNSRIDREELC RSAECSIHLEVIVDRPLQVFHVD
Sbjct: 61  PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD 120

Query: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180
           VEV+D+NDNPPVF    + L ++ESR  DSRFPLEGASDAD+G N++LTYRLS ++YF L
Sbjct: 121 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL 180

Query: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240
           +    ++  K + L+LRKSLDRE+AP   L LTATDGGKPELTGTVQLL+TVLD NDNAP
Sbjct: 181 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP 240

Query: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300
            F+++ Y+VR+ EN  NGT VIKLNASD DEG NG I YSF++ +   V   F ID  TG
Sbjct: 241 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG 300

Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360
           +I+++G +DFE+   Y+I+++  DKG  P++GHC V+V + D NDNVP++   SLSLP+R
Sbjct: 301 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR 360

Query: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420
           EDA  GTVIALISV+D D G NG VTCSL  HVPFKLVSTFKNYYSLVLDSALDRE VSA
Sbjct: 361 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480
           YELVVTARDGGSPSLWATAS+SVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA 
Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480

Query: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQENALVSYSLVERRVGER+LSSY+SVH ESGKVYALQPLDHEELELLQFQV+ARDA
Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL PR GGTGGA S+LVP SVG GHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQP     RIPFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT 660

Query: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVLVSLVESGQAPKASSR   G +GP+AALVDVNVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLP 777
           LRCSALPTEG C  GKPTLVCSSAVGSWSYSQQ+  RVCSGEGPPKTDLMAFSP LP
Sbjct: 721 LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLP 777


>gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens]
          Length = 947

 Score = 1206 bits (3121), Expect = 0.0
 Identities = 614/777 (79%), Positives = 671/777 (86%)

Query: 1   MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
           M++ W     S RLLLLLLLLAAW+ G+GQLHYSV EEAKHGTFVGRIAQDLGLELAELV
Sbjct: 1   MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLFRVASK    LLEV+LQNGILFVNSRIDREELC RSAECSIHLEVIVDRPLQVFHVD
Sbjct: 61  PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD 120

Query: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180
           VEV+D+NDNPPVF    + L ++ESR  DSRFPLEGASDAD+G N++LTYRLS ++YF L
Sbjct: 121 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL 180

Query: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240
           +    ++  K + L+LRKSLDRE+AP   L LTATDGGKPELTGTVQLL+TVLD NDNAP
Sbjct: 181 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP 240

Query: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300
            F+++ Y+VR+ EN  NGT VIKLNASD DEG NG I YSF++ +   V   F ID  TG
Sbjct: 241 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG 300

Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360
           +I+++G +DFE+   Y+I+++  DKG  P++GHC V+V + D NDNVP++   SLSLP+R
Sbjct: 301 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR 360

Query: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420
           EDA  GTVIALISV+D D G NG VTCSL  HVPFKLVSTFKNYYSLVLDSALDRE VSA
Sbjct: 361 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480
           YELVVTARDGGSPSLWATAS+SVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA 
Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480

Query: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQENALVSYSLVERRVGER+LSSY+SVH ESGKVYALQPLDHEELELLQFQV+ARDA
Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL PR GGTGGA S+LVP SVG GHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQP     RIPFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT 660

Query: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVLVSLVESGQAPKASSR   G +GP+AALVDVNVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLP 777
           LRCSALPTEG C  GKPTLVCSSAVGSWSYSQQ+  RVCSGEGPPKTDLMAFSP LP
Sbjct: 721 LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLP 777


>gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo
           sapiens]
          Length = 844

 Score = 1203 bits (3112), Expect = 0.0
 Identities = 627/797 (78%), Positives = 679/797 (85%), Gaps = 3/797 (0%)

Query: 9   LGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68
           LG   LLL LLLLAAW+VGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLFRVAS
Sbjct: 8   LGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVAS 67

Query: 69  KRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVND 128
           KRH DLLEV+LQNGILFVNSRIDREELCGRS ECSIHLEVIVDRPLQVFHVDVEVKD+ND
Sbjct: 68  KRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDIND 127

Query: 129 NPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDE 188
           NPP F V +QKL + ESR+ DSRFPLEGASDADVG N++LTY+LS ++YF+LD+ +K D+
Sbjct: 128 NPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDK 187

Query: 189 NKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248
           +K   LVLRK LDRE+ P   L LTATDGGKPE TG+V LL+ VLD NDNAP F++  YE
Sbjct: 188 DKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYE 247

Query: 249 VRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNL 308
           V+++EN  N T VI+LNASD DEG N  + YSF+SLV   +   F I+  TGEI +   +
Sbjct: 248 VKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAI 307

Query: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368
           DFE  N Y+I +D TDKG+PPM GHCTVLV +LD+NDN PE+ +TSLSLPV+EDAQ GTV
Sbjct: 308 DFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTV 367

Query: 369 IALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTAR 428
           IALISV+D DSGANGQVTCSL PHVPFKLVST+KNYYSLVLDSALDRERVSAYELVVTAR
Sbjct: 368 IALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTAR 427

Query: 429 DGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488
           DGGSP LWATAS+SVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQENA
Sbjct: 428 DGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENA 487

Query: 489 LVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548
           LVSYSLVERR+GERSLSSY+SVH ESGKVYALQPLDHEELELLQFQVSARD GVPPLGSN
Sbjct: 488 LVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSN 547

Query: 549 VTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLS 608
           +TLQVFVLDENDNAPALL    G  GGA S+LV RSV AGHVVAKVRAVDADSGYNAWLS
Sbjct: 548 LTLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLS 607

Query: 609 YELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS 668
           YELQ AA   RIPFRVGLYTGEISTTR LDE DSPR RLLVLVKDHGEP+LTATATVLVS
Sbjct: 608 YELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVS 667

Query: 669 LVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPT 728
           LVE  QAPKASSR S GV  PE ALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA PT
Sbjct: 668 LVEGSQAPKASSRASVGV-APEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPT 726

Query: 729 EGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVDV-GE 787
           EG C   KPTLVCSSAVGSWSYSQQ+ QRVCSGEG PK DLMAFSP LPP    VDV GE
Sbjct: 727 EGACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPP-CPMVDVDGE 785

Query: 788 EQDLNVDHGLKVSPFKF 804
           +Q +  DH  KV  + F
Sbjct: 786 DQSIGGDHSRKVGYYVF 802


>gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo
           sapiens]
          Length = 948

 Score = 1200 bits (3104), Expect = 0.0
 Identities = 625/791 (79%), Positives = 676/791 (85%), Gaps = 3/791 (0%)

Query: 9   LGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68
           LG   LLL LLLLAAW+VGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLFRVAS
Sbjct: 8   LGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVAS 67

Query: 69  KRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVND 128
           KRH DLLEV+LQNGILFVNSRIDREELCGRS ECSIHLEVIVDRPLQVFHVDVEVKD+ND
Sbjct: 68  KRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDIND 127

Query: 129 NPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDE 188
           NPP F V +QKL + ESR+ DSRFPLEGASDADVG N++LTY+LS ++YF+LD+ +K D+
Sbjct: 128 NPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDK 187

Query: 189 NKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248
           +K   LVLRK LDRE+ P   L LTATDGGKPE TG+V LL+ VLD NDNAP F++  YE
Sbjct: 188 DKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYE 247

Query: 249 VRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNL 308
           V+++EN  N T VI+LNASD DEG N  + YSF+SLV   +   F I+  TGEI +   +
Sbjct: 248 VKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAI 307

Query: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368
           DFE  N Y+I +D TDKG+PPM GHCTVLV +LD+NDN PE+ +TSLSLPV+EDAQ GTV
Sbjct: 308 DFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTV 367

Query: 369 IALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTAR 428
           IALISV+D DSGANGQVTCSL PHVPFKLVST+KNYYSLVLDSALDRERVSAYELVVTAR
Sbjct: 368 IALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTAR 427

Query: 429 DGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488
           DGGSP LWATAS+SVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQENA
Sbjct: 428 DGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENA 487

Query: 489 LVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548
           LVSYSLVERR+GERSLSSY+SVH ESGKVYALQPLDHEELELLQFQVSARD GVPPLGSN
Sbjct: 488 LVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSN 547

Query: 549 VTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLS 608
           +TLQVFVLDENDNAPALL    G  GGA S+LV RSV AGHVVAKVRAVDADSGYNAWLS
Sbjct: 548 LTLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLS 607

Query: 609 YELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS 668
           YELQ AA   RIPFRVGLYTGEISTTR LDE DSPR RLLVLVKDHGEP+LTATATVLVS
Sbjct: 608 YELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVS 667

Query: 669 LVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPT 728
           LVE  QAPKASSR S GV  PE ALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA PT
Sbjct: 668 LVEGSQAPKASSRASVGV-APEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPT 726

Query: 729 EGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVDV-GE 787
           EG C   KPTLVCSSAVGSWSYSQQ+ QRVCSGEG PK DLMAFSP LPP    VDV GE
Sbjct: 727 EGACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPP-CPMVDVDGE 785

Query: 788 EQDLNVDHGLK 798
           +Q +  DH  K
Sbjct: 786 DQSIGGDHSRK 796


>gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo
           sapiens]
          Length = 789

 Score = 1192 bits (3084), Expect = 0.0
 Identities = 609/775 (78%), Positives = 663/775 (85%)

Query: 10  GSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69
           G   LLL +++LAAW+ G GQLHYSVPEEAKHG FVGRIAQDLGLELAELVPRLFR   K
Sbjct: 10  GGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCK 69

Query: 70  RHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDN 129
              DLLEV+LQNGILFVNSRIDREELCGRSAECSIHLEVIV+RPLQVFHVDVEVKD+NDN
Sbjct: 70  FRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDN 129

Query: 130 PPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDEN 189
           PPVF    + LF++ESR  DSRFPLEGASDAD+G N++LTYRLS ++YF LDV + N + 
Sbjct: 130 PPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQV 189

Query: 190 KLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249
           K + LVLRK LDRE+ P  HL LTATDGGKPELTGTVQLL+TVLD NDNAP F+++ Y V
Sbjct: 190 KPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTV 249

Query: 250 RIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLD 309
           ++ EN   GT VI  NASD DEG NG I YSF+S V   +   F +D  +G I + G++D
Sbjct: 250 KLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMD 309

Query: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369
           FE+   +KI ++A DKG PP+AGHCTVLV ++D NDN P++ LTSLSLP+ EDAQ GTVI
Sbjct: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369

Query: 370 ALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARD 429
            LISV D D G NGQVTCSL P VPFKLVSTFKNYYSLVLDSALDRE VSAYELVVTARD
Sbjct: 370 TLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429

Query: 430 GGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489
           GGSPSLWATAS+SVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL
Sbjct: 430 GGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNAL 489

Query: 490 VSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549
           VSYSLVE RVGER+LSSY+SVH ESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV
Sbjct: 490 VSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549

Query: 550 TLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609
           TLQVFVLDENDNAPALL PRVGGTGGA  +LVPRSVGAGHVVAKVRAVDADSGYNAWLSY
Sbjct: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609

Query: 610 ELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669
           ELQP A+   IPFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEP+LTATATVLVSL
Sbjct: 610 ELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSL 669

Query: 670 VESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTE 729
           VESGQAPKASSR S G+ GPE  LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA  +E
Sbjct: 670 VESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSE 729

Query: 730 GGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVD 784
           G C   KPTLVCSSAVGSWS+SQQ+ QRVCSGEGPPKTDLMAFSP LP    S D
Sbjct: 730 GACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTD 784


>gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens]
          Length = 937

 Score = 1192 bits (3084), Expect = 0.0
 Identities = 609/775 (78%), Positives = 663/775 (85%)

Query: 10  GSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69
           G   LLL +++LAAW+ G GQLHYSVPEEAKHG FVGRIAQDLGLELAELVPRLFR   K
Sbjct: 10  GGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCK 69

Query: 70  RHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDN 129
              DLLEV+LQNGILFVNSRIDREELCGRSAECSIHLEVIV+RPLQVFHVDVEVKD+NDN
Sbjct: 70  FRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDN 129

Query: 130 PPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDEN 189
           PPVF    + LF++ESR  DSRFPLEGASDAD+G N++LTYRLS ++YF LDV + N + 
Sbjct: 130 PPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQV 189

Query: 190 KLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249
           K + LVLRK LDRE+ P  HL LTATDGGKPELTGTVQLL+TVLD NDNAP F+++ Y V
Sbjct: 190 KPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTV 249

Query: 250 RIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLD 309
           ++ EN   GT VI  NASD DEG NG I YSF+S V   +   F +D  +G I + G++D
Sbjct: 250 KLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMD 309

Query: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369
           FE+   +KI ++A DKG PP+AGHCTVLV ++D NDN P++ LTSLSLP+ EDAQ GTVI
Sbjct: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369

Query: 370 ALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARD 429
            LISV D D G NGQVTCSL P VPFKLVSTFKNYYSLVLDSALDRE VSAYELVVTARD
Sbjct: 370 TLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429

Query: 430 GGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489
           GGSPSLWATAS+SVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL
Sbjct: 430 GGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNAL 489

Query: 490 VSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549
           VSYSLVE RVGER+LSSY+SVH ESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV
Sbjct: 490 VSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549

Query: 550 TLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609
           TLQVFVLDENDNAPALL PRVGGTGGA  +LVPRSVGAGHVVAKVRAVDADSGYNAWLSY
Sbjct: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609

Query: 610 ELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669
           ELQP A+   IPFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEP+LTATATVLVSL
Sbjct: 610 ELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSL 669

Query: 670 VESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTE 729
           VESGQAPKASSR S G+ GPE  LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA  +E
Sbjct: 670 VESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSE 729

Query: 730 GGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVD 784
           G C   KPTLVCSSAVGSWS+SQQ+ QRVCSGEGPPKTDLMAFSP LP    S D
Sbjct: 730 GACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTD 784


>gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo
           sapiens]
          Length = 792

 Score = 1191 bits (3081), Expect = 0.0
 Identities = 613/767 (79%), Positives = 663/767 (86%)

Query: 10  GSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69
           GS RLLL LLLLAAW+VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFRVASK
Sbjct: 10  GSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69

Query: 70  RHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDN 129
           RH DLLEV+LQNGILFVNSRIDRE+LCGRSAECSIHLEVIVDRPLQVFHVDVEVKD+NDN
Sbjct: 70  RHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDN 129

Query: 130 PPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDEN 189
           PPVFR ++QK+ VSES   DS FPLEGASDAD+G NS+LTY LS ++ F L + +K D++
Sbjct: 130 PPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDKS 189

Query: 190 KLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249
            L ELVLRK LDRE  P  +L L   DGGKPELTG+VQ+ +TVLDVNDN P F++  Y+V
Sbjct: 190 ILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYKV 249

Query: 250 RIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLD 309
            + EN  N T VI+LNASDPDEG NG ISY    ++       FSI+ +TGEI I G LD
Sbjct: 250 VLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGELD 309

Query: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369
           FE+ N Y+I ++A DKG P MAGH  VLV +LD NDNVPE+ +TSLSLPV+EDAQ GTVI
Sbjct: 310 FEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTVI 369

Query: 370 ALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARD 429
           ALISV+D DSGANGQV CSL PHVPFKLVST+KNYYSLVLDSALDRE VSAYELVVTARD
Sbjct: 370 ALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARD 429

Query: 430 GGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489
           GGSPSLWATA +SVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL
Sbjct: 430 GGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNAL 489

Query: 490 VSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549
           VSYSLVERRVGE +LSSY+SVH ESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV
Sbjct: 490 VSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549

Query: 550 TLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609
           TLQVFVLDENDNAPALL    G  GGA S+LVPRSVGAGHVVAKVRAVDADSGYNAWLSY
Sbjct: 550 TLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609

Query: 610 ELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669
           ELQPAA    IPF VGLYTGEISTTR+LDEAD+PRHRLLVLVKDHGEPALT+TATVLVSL
Sbjct: 610 ELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLVSL 669

Query: 670 VESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTE 729
           VE+GQAPK SSR S G + PEAALVD+NVYLIIAICAVSSLLVLTLLLYTALRCSA PT 
Sbjct: 670 VENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPPTV 729

Query: 730 GGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCL 776
             C  GKPTLVCSSAVGSWSYSQQ+ QRVCS E PPKTDLMAFSP L
Sbjct: 730 SRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776


>gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo
           sapiens]
          Length = 941

 Score = 1191 bits (3081), Expect = 0.0
 Identities = 613/767 (79%), Positives = 663/767 (86%)

Query: 10  GSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69
           GS RLLL LLLLAAW+VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFRVASK
Sbjct: 10  GSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69

Query: 70  RHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDN 129
           RH DLLEV+LQNGILFVNSRIDRE+LCGRSAECSIHLEVIVDRPLQVFHVDVEVKD+NDN
Sbjct: 70  RHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDN 129

Query: 130 PPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDEN 189
           PPVFR ++QK+ VSES   DS FPLEGASDAD+G NS+LTY LS ++ F L + +K D++
Sbjct: 130 PPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDKS 189

Query: 190 KLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249
            L ELVLRK LDRE  P  +L L   DGGKPELTG+VQ+ +TVLDVNDN P F++  Y+V
Sbjct: 190 ILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYKV 249

Query: 250 RIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLD 309
            + EN  N T VI+LNASDPDEG NG ISY    ++       FSI+ +TGEI I G LD
Sbjct: 250 VLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGELD 309

Query: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369
           FE+ N Y+I ++A DKG P MAGH  VLV +LD NDNVPE+ +TSLSLPV+EDAQ GTVI
Sbjct: 310 FEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTVI 369

Query: 370 ALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARD 429
           ALISV+D DSGANGQV CSL PHVPFKLVST+KNYYSLVLDSALDRE VSAYELVVTARD
Sbjct: 370 ALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARD 429

Query: 430 GGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489
           GGSPSLWATA +SVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL
Sbjct: 430 GGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNAL 489

Query: 490 VSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549
           VSYSLVERRVGE +LSSY+SVH ESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV
Sbjct: 490 VSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549

Query: 550 TLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609
           TLQVFVLDENDNAPALL    G  GGA S+LVPRSVGAGHVVAKVRAVDADSGYNAWLSY
Sbjct: 550 TLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609

Query: 610 ELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669
           ELQPAA    IPF VGLYTGEISTTR+LDEAD+PRHRLLVLVKDHGEPALT+TATVLVSL
Sbjct: 610 ELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLVSL 669

Query: 670 VESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTE 729
           VE+GQAPK SSR S G + PEAALVD+NVYLIIAICAVSSLLVLTLLLYTALRCSA PT 
Sbjct: 670 VENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPPTV 729

Query: 730 GGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCL 776
             C  GKPTLVCSSAVGSWSYSQQ+ QRVCS E PPKTDLMAFSP L
Sbjct: 730 SRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776


>gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens]
          Length = 842

 Score = 1185 bits (3066), Expect = 0.0
 Identities = 612/799 (76%), Positives = 673/799 (84%)

Query: 1   MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
           M Y  RG+     LLL LL+LA W VGSGQLHYSVPEEA+HGTFVGRIAQDLGLELAELV
Sbjct: 1   MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLF++ SK   DLLEV+LQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD
Sbjct: 61  PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120

Query: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180
           VEVKD+NDNPPVF    + LF++ESR  DSRFPLEGASDAD+G N++LTYRLS ++YF L
Sbjct: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180

Query: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240
           DV + N + K + LVLRK LDRE+ P  HL LTATDGGKPELTGTVQLL+TVLD NDNAP
Sbjct: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240

Query: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300
            F+++ Y V++ EN   GT VI  NASD DEG NG I YSF+S V   +   F +D  +G
Sbjct: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300

Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360
            I + G++DFE+   +KI ++A DKG PP+AGHCT+LV ++D NDN P++ + +LS+PV+
Sbjct: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360

Query: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420
           EDAQ GTVIALISV DLD+ ANGQVTCSL PHVPFKLVST+KNYYSLVLD ALDRE VSA
Sbjct: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480
           YELVVTARDGGSPSLWATA +SVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSAR
Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQENALVSYSLVERR+GERSLSSY+SVH ESGKVYALQPLDHEELELLQFQVSARDA
Sbjct: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL PR+ GT GA S++V RSVGAG VV KVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600

Query: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQP  +S  IPFRVGLYTGEISTTR LDE D+PR RLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660

Query: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVLVSLVESGQAPK+SSR S G  GPE  LVDVNVYLIIAICAVSSLLVLTLLLYT 
Sbjct: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720

Query: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL 780
           LRCSA+PTEG C  GKPTLVCSSAVGSWSYSQQ+ QRVCSGEG  KTDLMAFSP L P  
Sbjct: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780

Query: 781 GSVDVGEEQDLNVDHGLKV 799
           GS +   E   + D   KV
Sbjct: 781 GSTERTGEPSASSDSTGKV 799


>gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo
           sapiens]
          Length = 950

 Score = 1184 bits (3064), Expect = 0.0
 Identities = 610/794 (76%), Positives = 671/794 (84%)

Query: 1   MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
           M Y  RG+     LLL LL+LA W VGSGQLHYSVPEEA+HGTFVGRIAQDLGLELAELV
Sbjct: 1   MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLF++ SK   DLLEV+LQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD
Sbjct: 61  PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120

Query: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180
           VEVKD+NDNPPVF    + LF++ESR  DSRFPLEGASDAD+G N++LTYRLS ++YF L
Sbjct: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180

Query: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240
           DV + N + K + LVLRK LDRE+ P  HL LTATDGGKPELTGTVQLL+TVLD NDNAP
Sbjct: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240

Query: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300
            F+++ Y V++ EN   GT VI  NASD DEG NG I YSF+S V   +   F +D  +G
Sbjct: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300

Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360
            I + G++DFE+   +KI ++A DKG PP+AGHCT+LV ++D NDN P++ + +LS+PV+
Sbjct: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360

Query: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420
           EDAQ GTVIALISV DLD+ ANGQVTCSL PHVPFKLVST+KNYYSLVLD ALDRE VSA
Sbjct: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480
           YELVVTARDGGSPSLWATA +SVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSAR
Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQENALVSYSLVERR+GERSLSSY+SVH ESGKVYALQPLDHEELELLQFQVSARDA
Sbjct: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL PR+ GT GA S++V RSVGAG VV KVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600

Query: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQP  +S  IPFRVGLYTGEISTTR LDE D+PR RLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660

Query: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVLVSLVESGQAPK+SSR S G  GPE  LVDVNVYLIIAICAVSSLLVLTLLLYT 
Sbjct: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720

Query: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL 780
           LRCSA+PTEG C  GKPTLVCSSAVGSWSYSQQ+ QRVCSGEG  KTDLMAFSP L P  
Sbjct: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780

Query: 781 GSVDVGEEQDLNVD 794
           GS +   E   + D
Sbjct: 781 GSTERTGEPSASSD 794


>gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo
           sapiens]
          Length = 824

 Score = 1179 bits (3050), Expect = 0.0
 Identities = 602/783 (76%), Positives = 667/783 (85%), Gaps = 3/783 (0%)

Query: 10  GSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69
           G+W  LL LLLLAAW+VGSGQL YSVPEEAKHGTFVGRIAQDLGLEL ELVPRLFRVASK
Sbjct: 10  GAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASK 69

Query: 70  RHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDN 129
           RH DLLEV+LQNGILFVNSRIDREELCGRSAECSIH+EVIVDRPLQVFHV+VEVKD+NDN
Sbjct: 70  RHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDN 129

Query: 130 PPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDEN 189
           PP+F +  + +   ESR+ DSRFPLEGASDAD+G N++L+Y+LSS ++F LD+ + ++ +
Sbjct: 130 PPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELS 189

Query: 190 KLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249
           + + LVL KSLDRE+    +L L ATDGGKPELTGTVQ+L+ VLDVNDN PTF QS Y+V
Sbjct: 190 ESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKV 249

Query: 250 RIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLD 309
           ++ EN  NGT V+KLNASD DEG N  I YS  S V + +   F+ID  +GEI  +G LD
Sbjct: 250 KLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLD 309

Query: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369
           +E+   Y+I + ATDKG P M+GHC + ++++D NDN PE+++TSLSLP+ E+A  GTVI
Sbjct: 310 YEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVI 369

Query: 370 ALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARD 429
           ALI+V+D DSG NG VTCSL PHVPFKLVSTFKNYYSLVLDSALDRE VSAYELVVTARD
Sbjct: 370 ALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429

Query: 430 GGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489
           GGSPSLWAT S+S+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQENAL
Sbjct: 430 GGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENAL 489

Query: 490 VSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549
           VSYSLVERRVGER+LSSY+SVH ESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLGSNV
Sbjct: 490 VSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNV 549

Query: 550 TLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609
           TLQVFVLDENDNAPALL PR G   GA S+LVP SVGAGHVVAKVRAVDADSGYNAWLSY
Sbjct: 550 TLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSY 609

Query: 610 ELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669
           ELQ    S RIPFRVGLYTGEISTTR LDEADSPRHRLLVLVKDHGEPALTATATVLVSL
Sbjct: 610 ELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669

Query: 670 VESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTE 729
           VESGQAPKASSR   G  G EA LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS  PTE
Sbjct: 670 VESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTE 729

Query: 730 GGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVDVGEEQ 789
           G    GKPTLVCSSAVGSWSYSQQ+ QRVCSGE PPKTDLMAFSP L       D  EE+
Sbjct: 730 GARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQ---GPDSAEEK 786

Query: 790 DLN 792
            L+
Sbjct: 787 QLS 789


>gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens]
          Length = 948

 Score = 1179 bits (3050), Expect = 0.0
 Identities = 602/783 (76%), Positives = 667/783 (85%), Gaps = 3/783 (0%)

Query: 10  GSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69
           G+W  LL LLLLAAW+VGSGQL YSVPEEAKHGTFVGRIAQDLGLEL ELVPRLFRVASK
Sbjct: 10  GAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASK 69

Query: 70  RHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDN 129
           RH DLLEV+LQNGILFVNSRIDREELCGRSAECSIH+EVIVDRPLQVFHV+VEVKD+NDN
Sbjct: 70  RHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDN 129

Query: 130 PPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDEN 189
           PP+F +  + +   ESR+ DSRFPLEGASDAD+G N++L+Y+LSS ++F LD+ + ++ +
Sbjct: 130 PPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELS 189

Query: 190 KLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249
           + + LVL KSLDRE+    +L L ATDGGKPELTGTVQ+L+ VLDVNDN PTF QS Y+V
Sbjct: 190 ESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKV 249

Query: 250 RIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLD 309
           ++ EN  NGT V+KLNASD DEG N  I YS  S V + +   F+ID  +GEI  +G LD
Sbjct: 250 KLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLD 309

Query: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369
           +E+   Y+I + ATDKG P M+GHC + ++++D NDN PE+++TSLSLP+ E+A  GTVI
Sbjct: 310 YEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVI 369

Query: 370 ALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARD 429
           ALI+V+D DSG NG VTCSL PHVPFKLVSTFKNYYSLVLDSALDRE VSAYELVVTARD
Sbjct: 370 ALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429

Query: 430 GGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489
           GGSPSLWAT S+S+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQENAL
Sbjct: 430 GGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENAL 489

Query: 490 VSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549
           VSYSLVERRVGER+LSSY+SVH ESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLGSNV
Sbjct: 490 VSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNV 549

Query: 550 TLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609
           TLQVFVLDENDNAPALL PR G   GA S+LVP SVGAGHVVAKVRAVDADSGYNAWLSY
Sbjct: 550 TLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSY 609

Query: 610 ELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669
           ELQ    S RIPFRVGLYTGEISTTR LDEADSPRHRLLVLVKDHGEPALTATATVLVSL
Sbjct: 610 ELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669

Query: 670 VESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTE 729
           VESGQAPKASSR   G  G EA LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS  PTE
Sbjct: 670 VESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTE 729

Query: 730 GGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVDVGEEQ 789
           G    GKPTLVCSSAVGSWSYSQQ+ QRVCSGE PPKTDLMAFSP L       D  EE+
Sbjct: 730 GARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQ---GPDSAEEK 786

Query: 790 DLN 792
            L+
Sbjct: 787 QLS 789


>gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo
           sapiens]
          Length = 686

 Score =  942 bits (2435), Expect = 0.0
 Identities = 476/526 (90%), Positives = 501/526 (95%)

Query: 9   LGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68
           LG   LLL LLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFR+AS
Sbjct: 9   LGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMAS 68

Query: 69  KRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVND 128
           K   DLLEV+LQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEV+D+ND
Sbjct: 69  KDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDIND 128

Query: 129 NPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDE 188
           NPP+F V++Q++ + ESR+PDS FPLEGASDADVG+NS+LTY+LSS +YF LDV   +D+
Sbjct: 129 NPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDD 188

Query: 189 NKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248
           NK + L+L+KSLDRE+APAH+LFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE
Sbjct: 189 NKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248

Query: 249 VRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNL 308
           VRIFENADNGTTVI+LNASD DEGANGAISYSFNSLV  MVIDHFSIDRNTGEIVIRGNL
Sbjct: 249 VRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNL 308

Query: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368
           DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV
Sbjct: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368

Query: 369 IALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTAR 428
           IALISVNDLDSGANGQV CSL PHVPFKLVSTFKNYYSLVLDSALDRE VSAYELVVTAR
Sbjct: 369 IALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTAR 428

Query: 429 DGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488
           DGGSPSLWATASLSVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA
Sbjct: 429 DGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488

Query: 489 LVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQ 534
           LVSYSLVERRVGER+LSSYISVH ESGKVYALQPLDHEELELLQFQ
Sbjct: 489 LVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQ 534



 Score =  162 bits (411), Expect = 9e-40
 Identities = 116/394 (29%), Positives = 187/394 (47%), Gaps = 32/394 (8%)

Query: 230 VTVLDVNDNAPTFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMV 289
           V V D+NDN P F   E  V I+E+    +      ASD D G+N  ++Y  +S      
Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSS----- 175

Query: 290 IDHFSIDRNTGE-------IVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILD 342
            ++F +D            ++++ +LD E+   + + + ATD G P + G   +LV +LD
Sbjct: 176 -EYFGLDVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLD 234

Query: 343 KNDNVPEIALTSLSLPVREDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTF- 401
            NDN P    +   + + E+A  GT +  ++ +D D GANG ++ S    V   ++  F 
Sbjct: 235 VNDNAPTFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFS 294

Query: 402 --KNYYSLVLDSALDRERVSAYELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPE 459
             +N   +V+   LD E+ + Y++++ A D G P +    ++ V + D NDN P  A   
Sbjct: 295 IDRNTGEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTS 354

Query: 460 YTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGE--RSLSSYISVHTESGKV 517
            ++ V+E+   G  I  +S  D D+  N  V+ SL      +   +  +Y S+  +S   
Sbjct: 355 LSLPVREDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSA-- 412

Query: 518 YALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAA 577
                LD E +   +  V+ARD G P L +  +L V V D NDNAPA  +P         
Sbjct: 413 -----LDRESVSAYELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEY------- 460

Query: 578 SKLVPRSVGAGHVVAKVRAVDADSGYNAWLSYEL 611
           +  V  +   G  +  V A DAD+  NA +SY L
Sbjct: 461 TVFVKENNPPGCHIFTVSARDADAQENALVSYSL 494



 Score =  146 bits (369), Expect = 7e-35
 Identities = 106/341 (31%), Positives = 157/341 (46%), Gaps = 21/341 (6%)

Query: 338 VRILDKNDNVPEIALTSLSLPVREDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPF-- 395
           V + D NDN P   +    + + E     +V  L   +D D G+N  +T  L     F  
Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180

Query: 396 --KLVSTFKNYYSLVLDSALDRERVSAYELVVTARDGGSPSLWATASLSVEVADVNDNAP 453
             K+ S       L+L  +LDRE   A+ L +TA DGG P L  T  L V V DVNDNAP
Sbjct: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240

Query: 454 AFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERSLSSYISVHTE 513
            F Q EY V + EN   G  +  ++A D D   N  +SYS     +    +  + S+   
Sbjct: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSF--NSLVAAMVIDHFSIDRN 298

Query: 514 SGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLEPRVGGT 573
           +G++     LD E+  L +  + A D G PP+  + T+ V +LD+NDN P +    +   
Sbjct: 299 TGEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSL--- 355

Query: 574 GGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPAASSPRIPFR-VGLYTGEIS 632
               S  V      G V+A +   D DSG N  ++  L     +P +PF+ V  +    S
Sbjct: 356 ----SLPVREDAQFGTVIALISVNDLDSGANGQVNCSL-----TPHVPFKLVSTFKNYYS 406

Query: 633 TT--RVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVE 671
                 LD      + L+V  +D G P+L ATA++ V + +
Sbjct: 407 LVLDSALDRESVSAYELVVTARDGGSPSLWATASLSVEVAD 447



 Score = 88.6 bits (218), Expect = 2e-17
 Identities = 70/239 (29%), Positives = 103/239 (43%), Gaps = 23/239 (9%)

Query: 441 LSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVG 500
           + VEV D+NDN P F   E  V + E+  P        A DAD   N++++Y L      
Sbjct: 119 VDVEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKL------ 172

Query: 501 ERSLSSY----ISVHTESGKVYAL---QPLDHEELELLQFQVSARDAGVPPLGSNVTLQV 553
             S S Y    + ++++  K   L   + LD EE       ++A D G P L   V L V
Sbjct: 173 --SSSEYFGLDVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLV 230

Query: 554 FVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQP 613
            VLD NDNAP   +             +  +   G  V ++ A D D G N  +SY    
Sbjct: 231 TVLDVNDNAPTFEQSEY-------EVRIFENADNGTTVIRLNASDRDEGANGAISYSFNS 283

Query: 614 AASSPRIP-FRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVE 671
             ++  I  F +   TGEI     LD      +++L+   D G P +    TVLV +++
Sbjct: 284 LVAAMVIDHFSIDRNTGEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILD 342



 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 53/198 (26%), Positives = 86/198 (43%), Gaps = 22/198 (11%)

Query: 484 AQENALVSYSLVER--RVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAG 541
           AQ+  L    LV R  R+  +     + V+ ++G ++    +D EEL     + S     
Sbjct: 49  AQDLGLELAELVPRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEV 108

Query: 542 VPPLGSNVT-LQVFVLDENDNAPA--LLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVD 598
           +      V  + V V D NDN P   + E RV         L+  S     V     A D
Sbjct: 109 IVDRPLQVFHVDVEVRDINDNPPLFPVEEQRV---------LIYESRLPDSVFPLEGASD 159

Query: 599 ADSGYNAWLSYELQPAASSPRIPFRVGLYTGE-----ISTTRVLDEADSPRHRLLVLVKD 653
           AD G N+ L+Y+L   +SS      V + + +     +   + LD  ++P H L +   D
Sbjct: 160 ADVGSNSILTYKL---SSSEYFGLDVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATD 216

Query: 654 HGEPALTATATVLVSLVE 671
            G+P LT T  +LV++++
Sbjct: 217 GGKPELTGTVQLLVTVLD 234


>gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo
           sapiens]
          Length = 685

 Score =  804 bits (2076), Expect = 0.0
 Identities = 409/526 (77%), Positives = 454/526 (86%)

Query: 9   LGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68
           LG   LLL LLLLAAW+VGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLFRVAS
Sbjct: 8   LGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVAS 67

Query: 69  KRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVND 128
           KRH DLLEV+LQNGILFVNSRIDREELCGRS ECSIHLEVIVDRPLQVFHVDVEVKD+ND
Sbjct: 68  KRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDIND 127

Query: 129 NPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDE 188
           NPP F V +QKL + ESR+ DSRFPLEGASDADVG N++LTY+LS ++YF+LD+ +K D+
Sbjct: 128 NPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDK 187

Query: 189 NKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248
           +K   LVLRK LDRE+ P   L LTATDGGKPE TG+V LL+ VLD NDNAP F++  YE
Sbjct: 188 DKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYE 247

Query: 249 VRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNL 308
           V+++EN  N T VI+LNASD DEG N  + YSF+SLV   +   F I+  TGEI +   +
Sbjct: 248 VKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAI 307

Query: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368
           DFE  N Y+I +D TDKG+PPM GHCTVLV +LD+NDN PE+ +TSLSLPV+EDAQ GTV
Sbjct: 308 DFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTV 367

Query: 369 IALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTAR 428
           IALISV+D DSGANGQVTCSL PHVPFKLVST+KNYYSLVLDSALDRERVSAYELVVTAR
Sbjct: 368 IALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTAR 427

Query: 429 DGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488
           DGGSP LWATAS+SVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQENA
Sbjct: 428 DGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENA 487

Query: 489 LVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQ 534
           LVSYSLVERR+GERSLSSY+SVH ESGKVYALQPLDHEELELLQFQ
Sbjct: 488 LVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQ 533



 Score =  144 bits (362), Expect = 4e-34
 Identities = 116/387 (29%), Positives = 186/387 (48%), Gaps = 18/387 (4%)

Query: 230 VTVLDVNDNAPTFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMV 289
           V V D+NDN P F  +E ++ I E+    +      ASD D G N  ++Y   S  E  V
Sbjct: 120 VEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKL-SPNEYFV 178

Query: 290 IDHFSI-DRNTGEI-VIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNV 347
           +D  +  D++   + V+R  LD E+    K+L+ ATD G P   G  ++L+ +LD NDN 
Sbjct: 179 LDIINKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNA 238

Query: 348 PEIALTSLSLPVREDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTF---KNY 404
           P        + + E+    T++  ++ +D D G N ++  S    VP  +   F   +  
Sbjct: 239 PIFDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERT 298

Query: 405 YSLVLDSALDRERVSAYELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFV 464
             + ++ A+D E  + YE+ V   D G+P +    ++ VE+ D NDN+P       ++ V
Sbjct: 299 GEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPV 358

Query: 465 KENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLD 524
           KE+   G  I  +S  D D+  N  V+ SL    V  + +S+Y + ++    +     LD
Sbjct: 359 KEDAQVGTVIALISVSDHDSGANGQVTCSLTPH-VPFKLVSTYKNYYS----LVLDSALD 413

Query: 525 HEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRS 584
            E +   +  V+ARD G PPL +  ++ V V D NDNAPA  +          +  V  +
Sbjct: 414 RERVSAYELVVTARDGGSPPLWATASVSVEVADVNDNAPAFAQSEY-------TVFVKEN 466

Query: 585 VGAGHVVAKVRAVDADSGYNAWLSYEL 611
              G  +  V A DAD+  NA +SY L
Sbjct: 467 NPPGCHIFTVSAWDADAQENALVSYSL 493



 Score =  135 bits (340), Expect = 2e-31
 Identities = 102/341 (29%), Positives = 155/341 (45%), Gaps = 21/341 (6%)

Query: 338 VRILDKNDNVPEIALTSLSLPVREDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKL 397
           V + D NDN P  ++T   L + E     +   L   +D D G N  +T  L P+  F L
Sbjct: 120 VEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVL 179

Query: 398 VSTFKN----YYSLVLDSALDRERVSAYELVVTARDGGSPSLWATASLSVEVADVNDNAP 453
               K     +  LVL   LDRE     +L++TA DGG P    + SL + V D NDNAP
Sbjct: 180 DIINKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAP 239

Query: 454 AFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERSLSSYISVHTE 513
            F +P Y V + EN      +  ++A D+D   N  + YS     +   ++     ++  
Sbjct: 240 IFDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSS--LVPPTIRRKFWINER 297

Query: 514 SGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLEPRVGGT 573
           +G++     +D E+    +  V   D G PP+  + T+ V +LDENDN+P ++   +   
Sbjct: 298 TGEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSL--- 354

Query: 574 GGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPAASSPRIPFR-VGLYTGEIS 632
               S  V      G V+A +   D DSG N  ++  L     +P +PF+ V  Y    S
Sbjct: 355 ----SLPVKEDAQVGTVIALISVSDHDSGANGQVTCSL-----TPHVPFKLVSTYKNYYS 405

Query: 633 TT--RVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVE 671
                 LD      + L+V  +D G P L ATA+V V + +
Sbjct: 406 LVLDSALDRERVSAYELVVTARDGGSPPLWATASVSVEVAD 446



 Score = 88.2 bits (217), Expect = 3e-17
 Identities = 79/270 (29%), Positives = 114/270 (42%), Gaps = 15/270 (5%)

Query: 441 LSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVG 500
           + VEV D+NDN P F+  E  + + E+           A DAD  ENAL++Y L      
Sbjct: 118 VDVEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYF 177

Query: 501 ERSLSSYISVHTESGKVYALQPL-DHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDEN 559
              + +      +   V  L+ L D EE   L+  ++A D G P    +V+L + VLD N
Sbjct: 178 VLDIIN--KKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDAN 235

Query: 560 DNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPAASSP- 618
           DNAP    P          K+    V    V+ ++ A D+D G N  + Y          
Sbjct: 236 DNAPIFDRPVY------EVKMYENQVNQTLVI-RLNASDSDEGINKEMMYSFSSLVPPTI 288

Query: 619 RIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQAPKA 678
           R  F +   TGEI     +D  DS  + + V V D G P +    TVLV L++       
Sbjct: 289 RRKFWINERTGEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPE 348

Query: 679 SSRQSAGVLGPEAALVDVNVYLIIAICAVS 708
               S  +   E    D  V  +IA+ +VS
Sbjct: 349 VIVTSLSLPVKE----DAQVGTVIALISVS 374


>gi|14165402 protocadherin alpha 1 isoform 3 precursor [Homo
           sapiens]
          Length = 686

 Score =  796 bits (2055), Expect = 0.0
 Identities = 397/534 (74%), Positives = 456/534 (85%)

Query: 1   MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
           M +  RG LG+  LLL LLLLAAW+VGSGQLHYS+PEEAKHGTFVGR+AQDLGLELAELV
Sbjct: 1   MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60

Query: 61  PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLFRVASK HRDLLEV+LQNGILFVNSRIDREELC  SAECSIHLE+I DRPLQVFHV+
Sbjct: 61  PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120

Query: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180
           V+VKD+NDNPPVFR ++Q +F+ ESR+ +SRFP+EGA+DAD+GAN++LTY LS  DYF L
Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180

Query: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240
           DV + ++ +K + L LRK LDRE+ P  HL LTATDGGKPEL GTV+LL+TVLDVNDNAP
Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240

Query: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300
            F+Q+ Y V + E   NGT V  LNASD DEG NG + +SF+S +   + + F +D ++G
Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300

Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360
           EI +   LD+E+   Y+I + A DKG PPM+ HC VLV++LD NDN PE+A+TSL LP+R
Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360

Query: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420
           EDA   TVIALI+V+D DSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRE +S 
Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420

Query: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480
           YELVVTARDGGSPSLWATA +SVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR
Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQ 534
           DADAQENALVSYSLVERRVGER+LS+Y+SVH ESGKVYALQPLDHEELELLQFQ
Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQ 534



 Score =  153 bits (386), Expect = 7e-37
 Identities = 120/394 (30%), Positives = 182/394 (46%), Gaps = 32/394 (8%)

Query: 230 VTVLDVNDNAPTFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMV 289
           V V D+NDN P F   E  + I E+    +      A+D D GAN  ++Y+ +       
Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPS----- 175

Query: 290 IDHFSIDRNTGE-------IVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILD 342
            D+FS+D    +       + +R  LD E+     +L+ ATD G P + G   +L+ +LD
Sbjct: 176 -DYFSLDVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLD 234

Query: 343 KNDNVPEIALTSLSLPVREDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFK 402
            NDN P        + + E    GT++  ++ +D D G NG+V  S    +   +   FK
Sbjct: 235 VNDNAPLFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFK 294

Query: 403 NYYS---LVLDSALDRERVSAYELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPE 459
              S   + L   LD E   +YE+ V A D GSP +     + V+V DVNDNAP  A   
Sbjct: 295 VDSSSGEIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTS 354

Query: 460 YTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGE--RSLSSYISVHTESGKV 517
             + ++E+ P    I  ++  D D+  N  V+ SL+     +   +  +Y S+  +S   
Sbjct: 355 LYLPIREDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSA-- 412

Query: 518 YALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAA 577
                LD E L + +  V+ARD G P L +   + V V D NDNAPA  +P         
Sbjct: 413 -----LDRESLSVYELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEY------- 460

Query: 578 SKLVPRSVGAGHVVAKVRAVDADSGYNAWLSYEL 611
           +  V  +   G  +  V A DAD+  NA +SY L
Sbjct: 461 TVFVKENNPPGCHIFTVSARDADAQENALVSYSL 494



 Score =  139 bits (350), Expect = 1e-32
 Identities = 110/345 (31%), Positives = 153/345 (44%), Gaps = 25/345 (7%)

Query: 336 VLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPF 395
           V V++ D NDN P        + + E     +   +    D D GAN  +T +L P   F
Sbjct: 119 VEVKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYF 178

Query: 396 KLVSTFKNYYS----LVLDSALDRERVSAYELVVTARDGGSPSLWATASLSVEVADVNDN 451
            L     +  S    L L   LDRE      L++TA DGG P L  T  L + V DVNDN
Sbjct: 179 SLDVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDN 238

Query: 452 APAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERSLSSYISVH 511
           AP F Q  Y V + E    G  + T++A DAD   N  V +S        R +     V 
Sbjct: 239 APLFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGI--SRDIQEKFKVD 296

Query: 512 TESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLEPRVG 571
           + SG++  +  LD+EE +  + QV A D G PP+ ++  + V VLD NDNAP L      
Sbjct: 297 SSSGEIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPEL------ 350

Query: 572 GTGGAASKLVP--RSVGAGHVVAKVRAVDADSGYNAWLSYELQPAASSPRIPFR-VGLYT 628
                 S  +P         V+A +   D DSG N  ++  L      P +PF+ V  + 
Sbjct: 351 ---AVTSLYLPIREDAPLSTVIALITVSDRDSGANGQVTCSLM-----PHVPFKLVSTFK 402

Query: 629 GEISTT--RVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVE 671
              S      LD      + L+V  +D G P+L ATA V V + +
Sbjct: 403 NYYSLVLDSALDRESLSVYELVVTARDGGSPSLWATARVSVEVAD 447


>gi|14277677 protocadherin gamma subfamily C, 3 isoform 2 precursor
           [Homo sapiens]
          Length = 863

 Score =  610 bits (1574), Expect = e-174
 Identities = 321/712 (45%), Positives = 457/712 (64%), Gaps = 9/712 (1%)

Query: 5   WR-GELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRL 63
           WR G + + R++ +LLLL A    S  +HY +PEE + G  VG +  +LGL+L  L  R 
Sbjct: 6   WRSGLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARR 65

Query: 64  FRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEV 123
           FRV S   R   EV+ + G +FVN R+DREELCG    C++ LE++V+ PL++F V+V +
Sbjct: 66  FRVVSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVI 125

Query: 124 KDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVN 183
           +D+NDN P F  ++ KL +SE+  P +RFPLE A D DVG+NS+ TY LS ++YF L V 
Sbjct: 126 QDINDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQ 185

Query: 184 SKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFE 243
           ++ D  K  ELVL ++LDRE  P+  L LTA DGG P L+ ++ + + VLD NDNAP F 
Sbjct: 186 TREDSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFN 245

Query: 244 QSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIV 303
           QS Y  R+ E+A +GT V+++ A+D DEG NG I YSF S     V   F++D  TG + 
Sbjct: 246 QSLYRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLT 305

Query: 304 IRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDA 363
           I+G LDFE   L++I I A DKG  P   HC VLV ++D NDN PEI +TS+  PV EDA
Sbjct: 306 IKGRLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDA 365

Query: 364 QFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYEL 423
             GTVIAL+SV DLD+G NG VTC + P +PF L S+ KNY++L   + LDRE V  Y L
Sbjct: 366 PLGTVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNL 425

Query: 424 VVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDAD 483
            +TARD G+PSL A   + V+V+D+NDN P  +Q  Y V+++ENN PG  I  +S  D D
Sbjct: 426 SITARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPD 485

Query: 484 AQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVP 543
           A +NA +S+ L+E+      +  Y +++ ++G V +L PLD+E+    +      D G P
Sbjct: 486 APQNARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTP 545

Query: 544 PLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGY 603
            L +N+++ +FV D NDNAP +L PR    GG++ +++PR   AGH+V++V   DAD+G+
Sbjct: 546 VLATNISVNIFVTDRNDNAPQVLYPR---PGGSSVEMLPRGTSAGHLVSRVVGWDADAGH 602

Query: 604 NAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATA 663
           NAWLSY L    S  +  F +GL+TG+IST R + + DSPR  L VL+KD+GEP+L+ TA
Sbjct: 603 NAWLSYSL--LGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTA 660

Query: 664 TVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTL 715
           T+ VS+ E   +P+A +   +G   P     ++  YL++++  VS   V+T+
Sbjct: 661 TLTVSVTE--DSPEARAEFPSG-SAPREQKKNLTFYLLLSLILVSVGFVVTV 709


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.134    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,607,199
Number of Sequences: 37866
Number of extensions: 1446536
Number of successful extensions: 10146
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 191
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 2988
Number of HSP's gapped (non-prelim): 730
length of query: 814
length of database: 18,247,518
effective HSP length: 111
effective length of query: 703
effective length of database: 14,044,392
effective search space: 9873207576
effective search space used: 9873207576
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.