BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo sapiens] (824 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo sapi... 1617 0.0 gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens] 1561 0.0 gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo sapi... 1275 0.0 gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens] 1272 0.0 gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo sapi... 1253 0.0 gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens] 1247 0.0 gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo sap... 1240 0.0 gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo sapi... 1239 0.0 gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens] 1238 0.0 gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo sapi... 1237 0.0 gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo sapi... 1236 0.0 gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens] 1234 0.0 gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens] 1233 0.0 gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo sapi... 1230 0.0 gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo sapi... 1228 0.0 gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens] 1226 0.0 gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo sapi... 1224 0.0 gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens] 1220 0.0 gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens] 1214 0.0 gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapi... 1211 0.0 gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo sap... 1194 0.0 gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo sapi... 1188 0.0 gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo sap... 1184 0.0 gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo sapi... 1184 0.0 gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo sap... 1169 0.0 gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo sapi... 1169 0.0 gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo sapi... 804 0.0 gi|14165402 protocadherin alpha 1 isoform 3 precursor [Homo sapi... 795 0.0 gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo sap... 774 0.0 gi|14277677 protocadherin gamma subfamily C, 3 isoform 2 precurs... 614 e-176 >gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo sapiens] Length = 824 Score = 1617 bits (4187), Expect = 0.0 Identities = 824/824 (100%), Positives = 824/824 (100%) Query: 1 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE Sbjct: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 Query: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL Sbjct: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180 Query: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP Sbjct: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240 Query: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG Sbjct: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300 Query: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL Sbjct: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360 Query: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA Sbjct: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660 Query: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP Sbjct: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780 Query: 781 ISRDREEKQDVDVDLSAKVSNFYLFFPKCLCFSFLNVSTPLEIH 824 ISRDREEKQDVDVDLSAKVSNFYLFFPKCLCFSFLNVSTPLEIH Sbjct: 781 ISRDREEKQDVDVDLSAKVSNFYLFFPKCLCFSFLNVSTPLEIH 824 >gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1561 bits (4043), Expect = 0.0 Identities = 798/798 (100%), Positives = 798/798 (100%) Query: 1 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE Sbjct: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 Query: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL Sbjct: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180 Query: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP Sbjct: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240 Query: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG Sbjct: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300 Query: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL Sbjct: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360 Query: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA Sbjct: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660 Query: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP Sbjct: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780 Query: 781 ISRDREEKQDVDVDLSAK 798 ISRDREEKQDVDVDLSAK Sbjct: 781 ISRDREEKQDVDVDLSAK 798 >gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo sapiens] Length = 798 Score = 1275 bits (3299), Expect = 0.0 Identities = 657/800 (82%), Positives = 707/800 (88%), Gaps = 3/800 (0%) Query: 1 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 M FSW ++ LLL LLLLAA E G+GQLHYSVSEEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 PRLFRVASK G LLEVNLQNGILFVNSRIDREELC RSAECSIHLEVIVDRPLQVFHV+ Sbjct: 61 PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD 120 Query: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180 VEV+DINDN PVFP KNL I+ESR SRF LEGASDADIG N+LLTY L EYF+L Sbjct: 121 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL 180 Query: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240 + +DE +K LGL+L+K+L+RE+ P+ +L++TA DGGKPELTGT QL ITVLD NDNAP Sbjct: 181 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP 240 Query: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300 AF+RTIYKVRLLEN PNGTLV+ +NA+DLDEG+N DI YSF+ D+S ++ SKFH+DP+ G Sbjct: 241 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG 300 Query: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360 QI VKG IDFEESKSYEI VE DKG P+S HC V++E+ D NDNVP+L +SLSLP+ Sbjct: 301 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR 360 Query: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420 ED+PL TVIALISVSD+D GVNG VTCSLT HVPFKLVSTFKNYYSLVLDS LDRESVSA Sbjct: 361 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSA Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PR GG GGAVSELVP SVG GHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDE DAPRHRLLVLVKDHGEP+LT Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASS+A GA GP+AALVDVNVYLI+AICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780 LRCSA PTEG C PGKPTLVCSSAVGSWSYSQQR+ RVCSGEG PKTDLMAFSPSLP Sbjct: 721 LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPD-- 778 Query: 781 ISRDREEKQDVDVDLSAKVS 800 SRDRE++ + AKVS Sbjct: 779 -SRDREDQLQTTEESFAKVS 797 >gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens] Length = 947 Score = 1272 bits (3291), Expect = 0.0 Identities = 655/798 (82%), Positives = 705/798 (88%), Gaps = 3/798 (0%) Query: 1 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 M FSW ++ LLL LLLLAA E G+GQLHYSVSEEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 PRLFRVASK G LLEVNLQNGILFVNSRIDREELC RSAECSIHLEVIVDRPLQVFHV+ Sbjct: 61 PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD 120 Query: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180 VEV+DINDN PVFP KNL I+ESR SRF LEGASDADIG N+LLTY L EYF+L Sbjct: 121 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL 180 Query: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240 + +DE +K LGL+L+K+L+RE+ P+ +L++TA DGGKPELTGT QL ITVLD NDNAP Sbjct: 181 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP 240 Query: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300 AF+RTIYKVRLLEN PNGTLV+ +NA+DLDEG+N DI YSF+ D+S ++ SKFH+DP+ G Sbjct: 241 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG 300 Query: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360 QI VKG IDFEESKSYEI VE DKG P+S HC V++E+ D NDNVP+L +SLSLP+ Sbjct: 301 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR 360 Query: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420 ED+PL TVIALISVSD+D GVNG VTCSLT HVPFKLVSTFKNYYSLVLDS LDRESVSA Sbjct: 361 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSA Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PR GG GGAVSELVP SVG GHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDE DAPRHRLLVLVKDHGEP+LT Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASS+A GA GP+AALVDVNVYLI+AICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780 LRCSA PTEG C PGKPTLVCSSAVGSWSYSQQR+ RVCSGEG PKTDLMAFSPSLP Sbjct: 721 LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPD-- 778 Query: 781 ISRDREEKQDVDVDLSAK 798 SRDRE++ + AK Sbjct: 779 -SRDREDQLQTTEESFAK 795 >gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo sapiens] Length = 803 Score = 1253 bits (3241), Expect = 0.0 Identities = 635/802 (79%), Positives = 702/802 (87%) Query: 1 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 M+F+ + G QCLLL LLLLAA +VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 PRLFR+ASK DLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+ Sbjct: 61 PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 Query: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180 VEV+DINDN P+FP+ + + I ESR P S F LEGASDAD+G+NS+LTY L S+EYF L Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180 Query: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240 DVK N ++ K +GL+LKK+L+RE+ P H L +TA DGGKPELTGT QL +TVLDVNDNAP Sbjct: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 Query: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300 FE++ Y+VR+ ENA NGT V+ +NA+D DEG N I+YSFN+ ++A ++ F +D G Sbjct: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300 Query: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360 +I ++GN+DFE+ Y+I ++ATDKG+PPM+ HCTVL+ I+D NDNVPE+ + SLSLPV Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 Query: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420 ED+ TVIALISV+D DSG NGQV CSLTPHVPFKLVSTFKNYYSLVLDS LDRESVSA Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATAS+SVEVAD+NDNAPAF+Q EYTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERRVGERALSSY+SVHAESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PRVGG GGAVSELVPRS+GAG VVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660 SGYNAWLSYELQP AR PFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEP+LT Sbjct: 601 SGYNAWLSYELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASS+AS GA GPEAALVDVNVYLI+AICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780 LRCSAPPTEG C KPTLVCSSAVGSWSYSQQR+QRVCSGEG PK DLMAFSPSL PCP Sbjct: 721 LRCSAPPTEGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCP 780 Query: 781 ISRDREEKQDVDVDLSAKVSNF 802 I + E QD++ D AKVS F Sbjct: 781 IMMGKAENQDLNEDHDAKVSEF 802 >gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1247 bits (3227), Expect = 0.0 Identities = 632/798 (79%), Positives = 699/798 (87%) Query: 1 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 M+F+ + G QCLLL LLLLAA +VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 PRLFR+ASK DLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+ Sbjct: 61 PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 Query: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180 VEV+DINDN P+FP+ + + I ESR P S F LEGASDAD+G+NS+LTY L S+EYF L Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180 Query: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240 DVK N ++ K +GL+LKK+L+RE+ P H L +TA DGGKPELTGT QL +TVLDVNDNAP Sbjct: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 Query: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300 FE++ Y+VR+ ENA NGT V+ +NA+D DEG N I+YSFN+ ++A ++ F +D G Sbjct: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300 Query: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360 +I ++GN+DFE+ Y+I ++ATDKG+PPM+ HCTVL+ I+D NDNVPE+ + SLSLPV Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 Query: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420 ED+ TVIALISV+D DSG NGQV CSLTPHVPFKLVSTFKNYYSLVLDS LDRESVSA Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATAS+SVEVAD+NDNAPAF+Q EYTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERRVGERALSSY+SVHAESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PRVGG GGAVSELVPRS+GAG VVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660 SGYNAWLSYELQP AR PFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEP+LT Sbjct: 601 SGYNAWLSYELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASS+AS GA GPEAALVDVNVYLI+AICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780 LRCSAPPTEG C KPTLVCSSAVGSWSYSQQR+QRVCSGEG PK DLMAFSPSL PCP Sbjct: 721 LRCSAPPTEGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCP 780 Query: 781 ISRDREEKQDVDVDLSAK 798 I + E QD++ D AK Sbjct: 781 IMMGKAENQDLNEDHDAK 798 >gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo sapiens] Length = 807 Score = 1240 bits (3209), Expect = 0.0 Identities = 632/803 (78%), Positives = 698/803 (86%) Query: 1 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 ML SW+ P + LLL LL+LAA E GSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE Sbjct: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 Query: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180 V+V+DINDN P+FP + K + I+ESR P +RF L+GASDADIG NS LTY LD +YFTL Sbjct: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180 Query: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240 D + + E++ SL LVL+K L+RE+ +H LL+TA DGGKPELTGT QL IT+LDVNDNAP Sbjct: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240 Query: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300 F +++YKV +LENA NGTLV+ +NATD D+G N DI YSF + ++ F ++P NG Sbjct: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300 Query: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360 +I KG +DFEE K YEI VEA DKGN PM+ HCT+L+E++D+NDN PE+ I SLSLP+ Sbjct: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360 Query: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420 ED+ S +IALISVSDRDSG NGQVTC+LTPHVPFKLVST+KNYYSLVLDS LDRESVSA Sbjct: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATASVSV VADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSA+ Sbjct: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD+ Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL P G GG VSEL+PRSVGAGHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660 SGYNAWLSYELQ GARIPFRVGLYTGEISTTR LDEVDAP HRLLVLVKDHGEP+LT Sbjct: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720 ATATVL+SLVESGQAP+ASS+ASAGA GPEAALVDVNVYLI+AICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780 LRCSAPPTEG C PGKPTLVCSSA GSWSYSQQR+ RVCSGEG KTDLMAFSPSLPPC Sbjct: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL 780 Query: 781 ISRDREEKQDVDVDLSAKVSNFY 803 S + +++ D + +VS ++ Sbjct: 781 GSAEGTGQREEDSECLKEVSLYF 803 >gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo sapiens] Length = 814 Score = 1239 bits (3205), Expect = 0.0 Identities = 632/802 (78%), Positives = 696/802 (86%) Query: 1 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 M + WR + G+ LLL LLLLAA +VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 PRLFRVASKRH DLLEV+LQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+ Sbjct: 61 PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 Query: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180 VEVKD+NDN PVF + + LF+SESR P SRF LEGASDAD+G NS+LTY L S +YF L Sbjct: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180 Query: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240 DV ++E K + LVL+K+L+RED P H+L +TA DGGKPELTGT QL +TVLDVNDNAP Sbjct: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 Query: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300 FE++ Y+VR+ ENA NGT V+ +NA+D DEG N I+YSFN+ + ++ F +D G Sbjct: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300 Query: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360 +I ++GN+DFE+ Y+I ++ATDKG+PPM+ HCTVL+ I+D NDNVPE+ + SLSLPV Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 Query: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420 ED+ TVIALISV+D DSG NGQVTCSL PHVPFKLVSTFKNYYSLVLDS LDRE VSA Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420 Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATAS+SVEVADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERRVGER+LSSY+SVH ESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PRVGG GGA S+LVPRSVGAGHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660 SGYNAWLSYELQP RIPFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEP+LT Sbjct: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASS+ SAG GPEAALVDVNVYLI+AICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780 LRCSA PTEG C GKPTLVCSSAVGSWSYSQQ+ QRVCSGEG PKTDLMAFSP LPP Sbjct: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL 780 Query: 781 ISRDREEKQDVDVDLSAKVSNF 802 S D E+QD++VD KVS F Sbjct: 781 GSVDVGEEQDLNVDHGLKVSPF 802 >gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens] Length = 842 Score = 1238 bits (3202), Expect = 0.0 Identities = 635/806 (78%), Positives = 701/806 (86%) Query: 1 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 ML+S R DP Q LLLSLL+LA VGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV Sbjct: 1 MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 PRLF++ SK GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+ Sbjct: 61 PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 Query: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180 VEVKDINDN PVFP KNLFI+ESR SRF LEGASDADIG N+LLTY L EYF L Sbjct: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180 Query: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240 DV +++++K LGLVL+K L+RE+TP+ +LL+TA DGGKPELTGT QL ITVLD NDNAP Sbjct: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240 Query: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300 F+RT+Y V+L EN GTLV+ NA+DLDEG+N DI YSF++D+S DI SKFH+DP++G Sbjct: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300 Query: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360 I+V G++DFEES++++I VEA DKG PP++ HCT+L+E+VD+NDN P+L I++LS+PV Sbjct: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360 Query: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420 ED+ L TVIALISV D D+ NGQVTCSLTPHVPFKLVST+KNYYSLVLD LDRESVSA Sbjct: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATA VSVEVADVNDNAPAF+QSEYTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PR+ G GAVSE+V RSVGAG VV KVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600 Query: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660 SGYNAWLSYELQP T A IPFRVGLYTGEISTTRALDE DAPR RLLVLVKDHGEP+LT Sbjct: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPK+SS+AS GATGPE LVDVNVYLI+AICAVSSLLVLTLLLYT Sbjct: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720 Query: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780 LRCSA PTEG+C PGKPTLVCSSAVGSWSYSQQR+QRVCSGEG KTDLMAFSP L PC Sbjct: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780 Query: 781 ISRDREEKQDVDVDLSAKVSNFYLFF 806 S +R + D + KV + F Sbjct: 781 GSTERTGEPSASSDSTGKVGFSSILF 806 >gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1237 bits (3201), Expect = 0.0 Identities = 630/792 (79%), Positives = 692/792 (87%) Query: 1 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 ML SW+ P + LLL LL+LAA E GSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE Sbjct: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 Query: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180 V+V+DINDN P+FP + K + I+ESR P +RF L+GASDADIG NS LTY LD +YFTL Sbjct: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180 Query: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240 D + + E++ SL LVL+K L+RE+ +H LL+TA DGGKPELTGT QL IT+LDVNDNAP Sbjct: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240 Query: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300 F +++YKV +LENA NGTLV+ +NATD D+G N DI YSF + ++ F ++P NG Sbjct: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300 Query: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360 +I KG +DFEE K YEI VEA DKGN PM+ HCT+L+E++D+NDN PE+ I SLSLP+ Sbjct: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360 Query: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420 ED+ S +IALISVSDRDSG NGQVTC+LTPHVPFKLVST+KNYYSLVLDS LDRESVSA Sbjct: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATASVSV VADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSA+ Sbjct: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD+ Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL P G GG VSEL+PRSVGAGHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660 SGYNAWLSYELQ GARIPFRVGLYTGEISTTR LDEVDAP HRLLVLVKDHGEP+LT Sbjct: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720 ATATVL+SLVESGQAP+ASS+ASAGA GPEAALVDVNVYLI+AICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780 LRCSAPPTEG C PGKPTLVCSSA GSWSYSQQR+ RVCSGEG KTDLMAFSPSLPPC Sbjct: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL 780 Query: 781 ISRDREEKQDVD 792 S + +++ D Sbjct: 781 GSAEGTGQREED 792 >gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1236 bits (3197), Expect = 0.0 Identities = 633/798 (79%), Positives = 698/798 (87%) Query: 1 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 ML+S R DP Q LLLSLL+LA VGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV Sbjct: 1 MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 PRLF++ SK GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+ Sbjct: 61 PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 Query: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180 VEVKDINDN PVFP KNLFI+ESR SRF LEGASDADIG N+LLTY L EYF L Sbjct: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180 Query: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240 DV +++++K LGLVL+K L+RE+TP+ +LL+TA DGGKPELTGT QL ITVLD NDNAP Sbjct: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240 Query: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300 F+RT+Y V+L EN GTLV+ NA+DLDEG+N DI YSF++D+S DI SKFH+DP++G Sbjct: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300 Query: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360 I+V G++DFEES++++I VEA DKG PP++ HCT+L+E+VD+NDN P+L I++LS+PV Sbjct: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360 Query: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420 ED+ L TVIALISV D D+ NGQVTCSLTPHVPFKLVST+KNYYSLVLD LDRESVSA Sbjct: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATA VSVEVADVNDNAPAF+QSEYTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PR+ G GAVSE+V RSVGAG VV KVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600 Query: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660 SGYNAWLSYELQP T A IPFRVGLYTGEISTTRALDE DAPR RLLVLVKDHGEP+LT Sbjct: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPK+SS+AS GATGPE LVDVNVYLI+AICAVSSLLVLTLLLYT Sbjct: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720 Query: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780 LRCSA PTEG+C PGKPTLVCSSAVGSWSYSQQR+QRVCSGEG KTDLMAFSP L PC Sbjct: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780 Query: 781 ISRDREEKQDVDVDLSAK 798 S +R + D + K Sbjct: 781 GSTERTGEPSASSDSTGK 798 >gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1234 bits (3193), Expect = 0.0 Identities = 629/798 (78%), Positives = 693/798 (86%) Query: 1 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 M + WR + G+ LLL LLLLAA +VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 PRLFRVASKRH DLLEV+LQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+ Sbjct: 61 PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 Query: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180 VEVKD+NDN PVF + + LF+SESR P SRF LEGASDAD+G NS+LTY L S +YF L Sbjct: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180 Query: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240 DV ++E K + LVL+K+L+RED P H+L +TA DGGKPELTGT QL +TVLDVNDNAP Sbjct: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 Query: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300 FE++ Y+VR+ ENA NGT V+ +NA+D DEG N I+YSFN+ + ++ F +D G Sbjct: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300 Query: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360 +I ++GN+DFE+ Y+I ++ATDKG+PPM+ HCTVL+ I+D NDNVPE+ + SLSLPV Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 Query: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420 ED+ TVIALISV+D DSG NGQVTCSL PHVPFKLVSTFKNYYSLVLDS LDRE VSA Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420 Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATAS+SVEVADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERRVGER+LSSY+SVH ESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PRVGG GGA S+LVPRSVGAGHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660 SGYNAWLSYELQP RIPFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEP+LT Sbjct: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASS+ SAG GPEAALVDVNVYLI+AICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780 LRCSA PTEG C GKPTLVCSSAVGSWSYSQQ+ QRVCSGEG PKTDLMAFSP LPP Sbjct: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL 780 Query: 781 ISRDREEKQDVDVDLSAK 798 S D E+QD++VD K Sbjct: 781 GSVDVGEEQDLNVDHGLK 798 >gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens] Length = 937 Score = 1233 bits (3190), Expect = 0.0 Identities = 633/792 (79%), Positives = 691/792 (87%) Query: 8 DPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67 DPG + LLL +++LAA E G GQLHYSV EEAKHG FVGRIAQDLGLELAELVPRLFR Sbjct: 8 DPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAV 67 Query: 68 SKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKDIN 127 K GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIV+RPLQVFHV+VEVKDIN Sbjct: 68 CKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDIN 127 Query: 128 DNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRNDE 187 DN PVFP +NLFI+ESR SRF LEGASDADIG N+LLTY L EYF LDV +++ Sbjct: 128 DNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQ 187 Query: 188 EIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIY 247 ++K LGLVL+K L+RE+TP+ +LL+TA DGGKPELTGT QL ITVLD NDNAP F+RT+Y Sbjct: 188 QVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLY 247 Query: 248 KVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGN 307 V+L EN GTLV+ NA+DLDEG+N DI YSF++D+S DI SKFH+DP++G I+V G+ Sbjct: 248 TVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGH 307 Query: 308 IDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSPLST 367 +DFEES++++I VEA DKG PP++ HCTVL+E+VD+NDN P+L + SLSLP+ ED+ T Sbjct: 308 MDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGT 367 Query: 368 VIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVVTA 427 VI LISV DRD GVNGQVTCSLTP VPFKLVSTFKNYYSLVLDS LDRESVSAYELVVTA Sbjct: 368 VITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTA 427 Query: 428 RDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADAQEN 487 RDGGSPSLWATASVSVEVADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSA DADAQ+N Sbjct: 428 RDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKN 487 Query: 488 ALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS 547 ALVSYSLVE RVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS Sbjct: 488 ALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS 547 Query: 548 NVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWL 607 NVTLQVFVLDENDNAPALL PRVGG GGAV ELVPRSVGAGHVVAKVRAVDADSGYNAWL Sbjct: 548 NVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWL 607 Query: 608 SYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLTATATVLV 667 SYELQP GA IPFRVGLYTGEISTTRALDE DAPRHRLLVLVKDHGEPSLTATATVLV Sbjct: 608 SYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLV 667 Query: 668 SLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTALRCSAPP 727 SLVESGQAPKASS+AS G GPE LVDVNVYLI+AICAVSSLLVLTLLLYTALRCSAP Sbjct: 668 SLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPS 727 Query: 728 TEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCPISRDREE 787 +EG C KPTLVCSSAVGSWS+SQQR+QRVCSGEG PKTDLMAFSPSLP P S D Sbjct: 728 SEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTDNPR 787 Query: 788 KQDVDVDLSAKV 799 + + D SA + Sbjct: 788 QPNPDWRYSASL 799 >gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo sapiens] Length = 789 Score = 1230 bits (3183), Expect = 0.0 Identities = 630/777 (81%), Positives = 685/777 (88%) Query: 8 DPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67 DPG + LLL +++LAA E G GQLHYSV EEAKHG FVGRIAQDLGLELAELVPRLFR Sbjct: 8 DPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAV 67 Query: 68 SKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKDIN 127 K GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIV+RPLQVFHV+VEVKDIN Sbjct: 68 CKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDIN 127 Query: 128 DNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRNDE 187 DN PVFP +NLFI+ESR SRF LEGASDADIG N+LLTY L EYF LDV +++ Sbjct: 128 DNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQ 187 Query: 188 EIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIY 247 ++K LGLVL+K L+RE+TP+ +LL+TA DGGKPELTGT QL ITVLD NDNAP F+RT+Y Sbjct: 188 QVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLY 247 Query: 248 KVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGN 307 V+L EN GTLV+ NA+DLDEG+N DI YSF++D+S DI SKFH+DP++G I+V G+ Sbjct: 248 TVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGH 307 Query: 308 IDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSPLST 367 +DFEES++++I VEA DKG PP++ HCTVL+E+VD+NDN P+L + SLSLP+ ED+ T Sbjct: 308 MDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGT 367 Query: 368 VIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVVTA 427 VI LISV DRD GVNGQVTCSLTP VPFKLVSTFKNYYSLVLDS LDRESVSAYELVVTA Sbjct: 368 VITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTA 427 Query: 428 RDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADAQEN 487 RDGGSPSLWATASVSVEVADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSA DADAQ+N Sbjct: 428 RDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKN 487 Query: 488 ALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS 547 ALVSYSLVE RVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS Sbjct: 488 ALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS 547 Query: 548 NVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWL 607 NVTLQVFVLDENDNAPALL PRVGG GGAV ELVPRSVGAGHVVAKVRAVDADSGYNAWL Sbjct: 548 NVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWL 607 Query: 608 SYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLTATATVLV 667 SYELQP GA IPFRVGLYTGEISTTRALDE DAPRHRLLVLVKDHGEPSLTATATVLV Sbjct: 608 SYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLV 667 Query: 668 SLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTALRCSAPP 727 SLVESGQAPKASS+AS G GPE LVDVNVYLI+AICAVSSLLVLTLLLYTALRCSAP Sbjct: 668 SLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPS 727 Query: 728 TEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCPISRD 784 +EG C KPTLVCSSAVGSWS+SQQR+QRVCSGEG PKTDLMAFSPSLP P S D Sbjct: 728 SEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTD 784 >gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo sapiens] Length = 824 Score = 1228 bits (3178), Expect = 0.0 Identities = 638/800 (79%), Positives = 691/800 (86%), Gaps = 2/800 (0%) Query: 1 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 M S R GA LLSLLLLAA EVGSGQL YSV EEAKHGTFVGRIAQDLGLEL ELV Sbjct: 1 MASSIRRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELV 60 Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIH+EVIVDRPLQVFHVE Sbjct: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVE 120 Query: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180 VEVKDINDN P+FPM VK + ESR SRF LEGASDADIG N+LL+Y L S+E+F L Sbjct: 121 VEVKDINDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFL 180 Query: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240 D++ NDE +SL LVL K+L+RE+T + LL+ A DGGKPELTGT Q+ I VLDVNDN P Sbjct: 181 DIQANDELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEP 240 Query: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300 F +++YKV+LLEN NGTLVV +NA+D DEG N +I YS +D+S+ I +KF +DP++G Sbjct: 241 TFAQSVYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISG 300 Query: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360 +I KG +D+EE+KSYEIQV ATDKG P MS HC + L++VDINDN PE+ I SLSLP+ Sbjct: 301 EIRTKGKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPIS 360 Query: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420 E++ L TVIALI+VSDRDSG NG VTCSLTPHVPFKLVSTFKNYYSLVLDS LDRESVSA Sbjct: 361 ENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWAT SVS+EVADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSA Sbjct: 421 YELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PR G GAVSELVP SVGAGHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660 SGYNAWLSYELQ GTG ARIPFRVGLYTGEISTTRALDE D+PRHRLLVLVKDHGEP+LT Sbjct: 601 SGYNAWLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASS+A GA G EA LVDVNVYLI+AICAVSSLLVLT+LLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTA 720 Query: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780 LRCS PPTEG PGKPTLVCSSAVGSWSYSQQR+QRVCSGE PKTDLMAFSPSL P Sbjct: 721 LRCSVPPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP 780 Query: 781 ISRDREEKQDVDVDLSAKVS 800 S EEKQ + + KVS Sbjct: 781 DS--AEEKQLSESEYVGKVS 798 >gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens] Length = 948 Score = 1226 bits (3172), Expect = 0.0 Identities = 635/789 (80%), Positives = 686/789 (86%), Gaps = 2/789 (0%) Query: 1 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 M S R GA LLSLLLLAA EVGSGQL YSV EEAKHGTFVGRIAQDLGLEL ELV Sbjct: 1 MASSIRRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELV 60 Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIH+EVIVDRPLQVFHVE Sbjct: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVE 120 Query: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180 VEVKDINDN P+FPM VK + ESR SRF LEGASDADIG N+LL+Y L S+E+F L Sbjct: 121 VEVKDINDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFL 180 Query: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240 D++ NDE +SL LVL K+L+RE+T + LL+ A DGGKPELTGT Q+ I VLDVNDN P Sbjct: 181 DIQANDELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEP 240 Query: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300 F +++YKV+LLEN NGTLVV +NA+D DEG N +I YS +D+S+ I +KF +DP++G Sbjct: 241 TFAQSVYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISG 300 Query: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360 +I KG +D+EE+KSYEIQV ATDKG P MS HC + L++VDINDN PE+ I SLSLP+ Sbjct: 301 EIRTKGKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPIS 360 Query: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420 E++ L TVIALI+VSDRDSG NG VTCSLTPHVPFKLVSTFKNYYSLVLDS LDRESVSA Sbjct: 361 ENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWAT SVS+EVADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSA Sbjct: 421 YELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PR G GAVSELVP SVGAGHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660 SGYNAWLSYELQ GTG ARIPFRVGLYTGEISTTRALDE D+PRHRLLVLVKDHGEP+LT Sbjct: 601 SGYNAWLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASS+A GA G EA LVDVNVYLI+AICAVSSLLVLT+LLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTA 720 Query: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780 LRCS PPTEG PGKPTLVCSSAVGSWSYSQQR+QRVCSGE PKTDLMAFSPSL P Sbjct: 721 LRCSVPPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP 780 Query: 781 ISRDREEKQ 789 S EEKQ Sbjct: 781 DS--AEEKQ 787 >gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo sapiens] Length = 807 Score = 1224 bits (3168), Expect = 0.0 Identities = 628/806 (77%), Positives = 700/806 (86%) Query: 1 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 M+FS R GA+ LLL LLLLAA EVGSGQLHYS+ EEAKHGTFVGR+AQDLGLELAELV Sbjct: 1 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60 Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 PRLFRVASK H DLLEVNLQNGILFVNSRIDREELC SAECSIHLE+I DRPLQVFHVE Sbjct: 61 PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120 Query: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180 V+VKDINDN PVF + +FI ESR SRF +EGA+DADIG N+LLTY+L ++YF+L Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180 Query: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240 DV+ +DE KSL L L+K L+RE+TP+ +LL+TA DGGKPEL GT +L ITVLDVNDNAP Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240 Query: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300 F++ +Y+V LLE NGTLV T+NA+D DEGVN ++ +SF++ +S DI KF +D +G Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300 Query: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360 +I + +D+EE+KSYEIQV+A DKG+PPMS+HC VL++++D+NDN PEL + SL LP+ Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360 Query: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420 ED+PLSTVIALI+VSDRDSG NGQVTCSL PHVPFKLVSTFKNYYSLVLDS LDRES+S Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420 Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATA VSVEVADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERRVGERALS+YVSVHAESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PRVGG GAVSELVPR VGAGHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660 SGYNAWLSYELQP GGARIPFRVGLYTGEISTTR LDE D R+RLLVLVKDHGEP+LT Sbjct: 601 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASS+AS G GPEAALVDVNVYLI+AICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780 LRCS PPTEG PGKPTLVCSSA+GSWS SQQR+QRVCS EG PKTDLMAFSP L P Sbjct: 721 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL 780 Query: 781 ISRDREEKQDVDVDLSAKVSNFYLFF 806 + +R E+ + ++DLS VS + F+ Sbjct: 781 NTSERNEQPEANLDLSGNVSPTFEFW 806 >gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1220 bits (3157), Expect = 0.0 Identities = 625/796 (78%), Positives = 695/796 (87%) Query: 1 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 M+FS R GA+ LLL LLLLAA EVGSGQLHYS+ EEAKHGTFVGR+AQDLGLELAELV Sbjct: 1 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60 Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 PRLFRVASK H DLLEVNLQNGILFVNSRIDREELC SAECSIHLE+I DRPLQVFHVE Sbjct: 61 PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120 Query: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180 V+VKDINDN PVF + +FI ESR SRF +EGA+DADIG N+LLTY+L ++YF+L Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180 Query: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240 DV+ +DE KSL L L+K L+RE+TP+ +LL+TA DGGKPEL GT +L ITVLDVNDNAP Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240 Query: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300 F++ +Y+V LLE NGTLV T+NA+D DEGVN ++ +SF++ +S DI KF +D +G Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300 Query: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360 +I + +D+EE+KSYEIQV+A DKG+PPMS+HC VL++++D+NDN PEL + SL LP+ Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360 Query: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420 ED+PLSTVIALI+VSDRDSG NGQVTCSL PHVPFKLVSTFKNYYSLVLDS LDRES+S Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420 Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATA VSVEVADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERRVGERALS+YVSVHAESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PRVGG GAVSELVPR VGAGHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660 SGYNAWLSYELQP GGARIPFRVGLYTGEISTTR LDE D R+RLLVLVKDHGEP+LT Sbjct: 601 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASS+AS G GPEAALVDVNVYLI+AICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780 LRCS PPTEG PGKPTLVCSSA+GSWS SQQR+QRVCS EG PKTDLMAFSP L P Sbjct: 721 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL 780 Query: 781 ISRDREEKQDVDVDLS 796 + +R E+ + ++DLS Sbjct: 781 NTSERNEQPEANLDLS 796 >gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens] Length = 936 Score = 1214 bits (3141), Expect = 0.0 Identities = 626/799 (78%), Positives = 685/799 (85%), Gaps = 1/799 (0%) Query: 1 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 M++S R G++ LLL LLLA + GSGQLHYS+ EEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MVYSRRGSLGSRLLLL-WLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59 Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 PRLFRVASK GDLLEVNLQNGILFVNSRIDREELC R AECSIHLEVIVDRPLQVFHVE Sbjct: 60 PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119 Query: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180 V VKDINDN P F + LFI ESR P SRF LEGASD DIG N+ L Y L+ EYF L Sbjct: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179 Query: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240 DVK N+EE L LVL+K+L+RE+T +H LL+ A DGGKPELTGT QL I VLD NDNAP Sbjct: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239 Query: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300 F+++IY VRLLENAP+GTLV+ +NA+D DEG+NK+I Y F+ + D+ SKF ++ G Sbjct: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299 Query: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360 +I V G +D+E+ SYEI ++A DK P+S HC V+++++D+NDN PE+ I +L LPV Sbjct: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359 Query: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420 ED+PLSTVIALISVSDRDSG NGQVTCSL PHVPFKLVSTFKNYYSLVLDS LDRESVS Sbjct: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419 Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAF+Q +YTVFVKENNPPGCHIFTVSAR Sbjct: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479 Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERRVGER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDA Sbjct: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL+PRVGG GGAVSELVPRSVGAGHVVAKVRAVD D Sbjct: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599 Query: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660 SGYNAWLSYELQP G ARIPFRVGLYTGEISTTR+LDE +APRHRLLVLVKDHGEP LT Sbjct: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659 Query: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASS+ASAGA GPEAALVDVNVYLI+AICAVSSLLVLTLLLYTA Sbjct: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719 Query: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780 LRCSA PTE C GKPTL+CSSAVGSWSYSQQR+QRVCSGE PKTDLMAFSPSLP P Sbjct: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGP 779 Query: 781 ISRDREEKQDVDVDLSAKV 799 S D + + D SA + Sbjct: 780 TSTDNPRQPNPDWRYSASL 798 >gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapiens] Length = 816 Score = 1211 bits (3134), Expect = 0.0 Identities = 623/784 (79%), Positives = 679/784 (86%), Gaps = 1/784 (0%) Query: 1 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 M++S R G++ LLL LLLA + GSGQLHYS+ EEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MVYSRRGSLGSRLLLL-WLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59 Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 PRLFRVASK GDLLEVNLQNGILFVNSRIDREELC R AECSIHLEVIVDRPLQVFHVE Sbjct: 60 PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119 Query: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180 V VKDINDN P F + LFI ESR P SRF LEGASD DIG N+ L Y L+ EYF L Sbjct: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179 Query: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240 DVK N+EE L LVL+K+L+RE+T +H LL+ A DGGKPELTGT QL I VLD NDNAP Sbjct: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239 Query: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300 F+++IY VRLLENAP+GTLV+ +NA+D DEG+NK+I Y F+ + D+ SKF ++ G Sbjct: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299 Query: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360 +I V G +D+E+ SYEI ++A DK P+S HC V+++++D+NDN PE+ I +L LPV Sbjct: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359 Query: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420 ED+PLSTVIALISVSDRDSG NGQVTCSL PHVPFKLVSTFKNYYSLVLDS LDRESVS Sbjct: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419 Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAF+Q +YTVFVKENNPPGCHIFTVSAR Sbjct: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479 Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERRVGER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDA Sbjct: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL+PRVGG GGAVSELVPRSVGAGHVVAKVRAVD D Sbjct: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599 Query: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660 SGYNAWLSYELQP G ARIPFRVGLYTGEISTTR+LDE +APRHRLLVLVKDHGEP LT Sbjct: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659 Query: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASS+ASAGA GPEAALVDVNVYLI+AICAVSSLLVLTLLLYTA Sbjct: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719 Query: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780 LRCSA PTE C GKPTL+CSSAVGSWSYSQQR+QRVCSGE PKTDLMAFSPSLP P Sbjct: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGP 779 Query: 781 ISRD 784 S D Sbjct: 780 TSTD 783 >gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo sapiens] Length = 844 Score = 1194 bits (3088), Expect = 0.0 Identities = 621/803 (77%), Positives = 676/803 (84%), Gaps = 3/803 (0%) Query: 10 GAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69 G QCLLLSLLLLAA EVGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLFRVASK Sbjct: 9 GVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASK 68 Query: 70 RHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKDINDN 129 RHGDLLEVNLQNGILFVNSRIDREELCGRS ECSIHLEVIVDRPLQVFHV+VEVKDINDN Sbjct: 69 RHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDN 128 Query: 130 APVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRNDEEI 189 P F + + L I ESR SRF LEGASDAD+G N+LLTY L EYF LD+ ++ Sbjct: 129 PPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKD 188 Query: 190 KSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIYKV 249 K LVL+K L+RE+ P+ LL+TA DGGKPE TG+ L I VLD NDNAP F+R +Y+V Sbjct: 189 KFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEV 248 Query: 250 RLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGNID 309 ++ EN N TLV+ +NA+D DEG+NK++ YSF++ + I KF ++ G+I V ID Sbjct: 249 KMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAID 308 Query: 310 FEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSPLSTVI 369 FE+S +YEI V+ TDKGNPPM HCTVL+E++D NDN PE+++ SLSLPV ED+ + TVI Sbjct: 309 FEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVI 368 Query: 370 ALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVVTARD 429 ALISVSD DSG NGQVTCSLTPHVPFKLVST+KNYYSLVLDS LDRE VSAYELVVTARD Sbjct: 369 ALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARD 428 Query: 430 GGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADAQENAL 489 GGSP LWATASVSVEVADVNDNAPAF+QSEYTVFVKENNPPGCHIFTVSA DADAQENAL Sbjct: 429 GGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENAL 488 Query: 490 VSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 VSYSLVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD GVPPLGSN+ Sbjct: 489 VSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNL 548 Query: 550 TLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609 TLQVFVLDENDNAPALL G GGAVSELV RSV AGHVVAKVRAVDADSGYNAWLSY Sbjct: 549 TLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSY 608 Query: 610 ELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLTATATVLVSL 669 ELQ GARIPFRVGLYTGEISTTRALDE D+PR RLLVLVKDHGEPSLTATATVLVSL Sbjct: 609 ELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSL 668 Query: 670 VESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTALRCSAPPTE 729 VE QAPKASS+AS G PE ALVDVNVYLI+AICAVSSLLVLTLLLYTALRCSA PTE Sbjct: 669 VEGSQAPKASSRASVG-VAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPTE 727 Query: 730 GDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCPISRDREEKQ 789 G CGP KPTLVCSSAVGSWSYSQQR+QRVCSGEGLPK DLMAFSPSLPPCP+ E Q Sbjct: 728 GACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCPMVDVDGEDQ 787 Query: 790 DVDVDLSAKVSNFYLFFPKCLCF 812 + D S KV + F LCF Sbjct: 788 SIGGDHSRKVGYYVFIF--LLCF 808 >gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo sapiens] Length = 948 Score = 1188 bits (3073), Expect = 0.0 Identities = 616/789 (78%), Positives = 670/789 (84%), Gaps = 1/789 (0%) Query: 10 GAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69 G QCLLLSLLLLAA EVGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLFRVASK Sbjct: 9 GVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASK 68 Query: 70 RHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKDINDN 129 RHGDLLEVNLQNGILFVNSRIDREELCGRS ECSIHLEVIVDRPLQVFHV+VEVKDINDN Sbjct: 69 RHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDN 128 Query: 130 APVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRNDEEI 189 P F + + L I ESR SRF LEGASDAD+G N+LLTY L EYF LD+ ++ Sbjct: 129 PPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKD 188 Query: 190 KSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIYKV 249 K LVL+K L+RE+ P+ LL+TA DGGKPE TG+ L I VLD NDNAP F+R +Y+V Sbjct: 189 KFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEV 248 Query: 250 RLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGNID 309 ++ EN N TLV+ +NA+D DEG+NK++ YSF++ + I KF ++ G+I V ID Sbjct: 249 KMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAID 308 Query: 310 FEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSPLSTVI 369 FE+S +YEI V+ TDKGNPPM HCTVL+E++D NDN PE+++ SLSLPV ED+ + TVI Sbjct: 309 FEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVI 368 Query: 370 ALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVVTARD 429 ALISVSD DSG NGQVTCSLTPHVPFKLVST+KNYYSLVLDS LDRE VSAYELVVTARD Sbjct: 369 ALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARD 428 Query: 430 GGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADAQENAL 489 GGSP LWATASVSVEVADVNDNAPAF+QSEYTVFVKENNPPGCHIFTVSA DADAQENAL Sbjct: 429 GGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENAL 488 Query: 490 VSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 VSYSLVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD GVPPLGSN+ Sbjct: 489 VSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNL 548 Query: 550 TLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609 TLQVFVLDENDNAPALL G GGAVSELV RSV AGHVVAKVRAVDADSGYNAWLSY Sbjct: 549 TLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSY 608 Query: 610 ELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLTATATVLVSL 669 ELQ GARIPFRVGLYTGEISTTRALDE D+PR RLLVLVKDHGEPSLTATATVLVSL Sbjct: 609 ELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSL 668 Query: 670 VESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTALRCSAPPTE 729 VE QAPKASS+AS G PE ALVDVNVYLI+AICAVSSLLVLTLLLYTALRCSA PTE Sbjct: 669 VEGSQAPKASSRASVG-VAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPTE 727 Query: 730 GDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCPISRDREEKQ 789 G CGP KPTLVCSSAVGSWSYSQQR+QRVCSGEGLPK DLMAFSPSLPPCP+ E Q Sbjct: 728 GACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCPMVDVDGEDQ 787 Query: 790 DVDVDLSAK 798 + D S K Sbjct: 788 SIGGDHSRK 796 >gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo sapiens] Length = 810 Score = 1184 bits (3063), Expect = 0.0 Identities = 617/795 (77%), Positives = 676/795 (85%), Gaps = 1/795 (0%) Query: 6 REDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFR 65 R G L L LLLL EVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV RLFR Sbjct: 6 RRGLGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFR 65 Query: 66 VASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKD 125 VASK HGDLLEVNLQNGILFVNSRIDREELCG+SAECSIHLEVIVDRPLQVFHV VEVKD Sbjct: 66 VASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKD 125 Query: 126 INDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRN 185 INDN PVF + + L I+ES+Q SRF LEGASDADI N+LLTY L EYF+LD N Sbjct: 126 INDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTN 185 Query: 186 DEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERT 245 ++IK L L+LKK+L+RE TP+ LL+TA DGGKPELTGT +L + VLDVNDN P F+++ Sbjct: 186 GKQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKS 245 Query: 246 IYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVK 305 YKV L+ENA TLV+ +NATD DEGVN ++ YS + + + F LD NG++ V Sbjct: 246 EYKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVN 304 Query: 306 GNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSPL 365 G +D+EE+K Y+I+V+ATDKG PPM+ HCTV +EI+D NDN PE+ + SLSLPV ED+ Sbjct: 305 GTLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQP 364 Query: 366 STVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVV 425 STVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDS LDRE+V AYELVV Sbjct: 365 STVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVV 424 Query: 426 TARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADAQ 485 TARDGGSPSLWATA VSVEVADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSARDADAQ Sbjct: 425 TARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQ 484 Query: 486 ENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL 545 ENALVSYSLVERR+G+RALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL Sbjct: 485 ENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL 544 Query: 546 GSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYNA 605 SNVTLQVFVLDENDNAPALL + G GGAV++LVPRSVGAGHVVAKVRAVDADSGYNA Sbjct: 545 SSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNA 604 Query: 606 WLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLTATATV 665 WLSYELQP GG+RIPFRVGLYTGEISTTRALDE D+PRHRLLVLVKDHGEP+LTATATV Sbjct: 605 WLSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATV 664 Query: 666 LVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTALRCSA 725 LVSLVESGQAPKASS+ AGA PEAALVDVNVYLI+AIC VSSLLVLTLLLYTAL SA Sbjct: 665 LVSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSA 724 Query: 726 PPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCPISRDR 785 PTEG C PGKPTLVCS AVGSWSYSQQR+QRVCS EG PKTDLMAFSPSLP + Sbjct: 725 TPTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNKEEE 784 Query: 786 EEKQDVDVDLSAKVS 800 E+Q+ + +VS Sbjct: 785 GERQEPGSNHPGQVS 799 >gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo sapiens] Length = 949 Score = 1184 bits (3062), Expect = 0.0 Identities = 615/785 (78%), Positives = 672/785 (85%), Gaps = 1/785 (0%) Query: 6 REDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFR 65 R G L L LLLL EVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV RLFR Sbjct: 6 RRGLGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFR 65 Query: 66 VASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKD 125 VASK HGDLLEVNLQNGILFVNSRIDREELCG+SAECSIHLEVIVDRPLQVFHV VEVKD Sbjct: 66 VASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKD 125 Query: 126 INDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRN 185 INDN PVF + + L I+ES+Q SRF LEGASDADI N+LLTY L EYF+LD N Sbjct: 126 INDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTN 185 Query: 186 DEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERT 245 ++IK L L+LKK+L+RE TP+ LL+TA DGGKPELTGT +L + VLDVNDN P F+++ Sbjct: 186 GKQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKS 245 Query: 246 IYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVK 305 YKV L+ENA TLV+ +NATD DEGVN ++ YS + + + F LD NG++ V Sbjct: 246 EYKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVN 304 Query: 306 GNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSPL 365 G +D+EE+K Y+I+V+ATDKG PPM+ HCTV +EI+D NDN PE+ + SLSLPV ED+ Sbjct: 305 GTLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQP 364 Query: 366 STVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVV 425 STVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDS LDRE+V AYELVV Sbjct: 365 STVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVV 424 Query: 426 TARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADAQ 485 TARDGGSPSLWATA VSVEVADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSARDADAQ Sbjct: 425 TARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQ 484 Query: 486 ENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL 545 ENALVSYSLVERR+G+RALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL Sbjct: 485 ENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL 544 Query: 546 GSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYNA 605 SNVTLQVFVLDENDNAPALL + G GGAV++LVPRSVGAGHVVAKVRAVDADSGYNA Sbjct: 545 SSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNA 604 Query: 606 WLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLTATATV 665 WLSYELQP GG+RIPFRVGLYTGEISTTRALDE D+PRHRLLVLVKDHGEP+LTATATV Sbjct: 605 WLSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATV 664 Query: 666 LVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTALRCSA 725 LVSLVESGQAPKASS+ AGA PEAALVDVNVYLI+AIC VSSLLVLTLLLYTAL SA Sbjct: 665 LVSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSA 724 Query: 726 PPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCPISRDR 785 PTEG C PGKPTLVCS AVGSWSYSQQR+QRVCS EG PKTDLMAFSPSLP + Sbjct: 725 TPTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNKEEE 784 Query: 786 EEKQD 790 E+Q+ Sbjct: 785 GERQE 789 >gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo sapiens] Length = 792 Score = 1169 bits (3025), Expect = 0.0 Identities = 605/768 (78%), Positives = 657/768 (85%) Query: 9 PGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68 PG+Q LLLSLLLLAA EVGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFRVAS Sbjct: 9 PGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68 Query: 69 KRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKDIND 128 KRHGDLLEVNLQNGILFVNSRIDRE+LCGRSAECSIHLEVIVDRPLQVFHV+VEVKDIND Sbjct: 69 KRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIND 128 Query: 129 NAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRNDEE 188 N PVF + + +SES S F LEGASDADIG NSLLTY+L E F L +K ++ Sbjct: 129 NPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDK 188 Query: 189 IKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIYK 248 LVL+K L+RE TPK LL+ IDGGKPELTG+ Q++ITVLDVNDN PAF++ YK Sbjct: 189 SILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYK 248 Query: 249 VRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGNI 308 V L EN N T V+ +NA+D DEG+N +I+Y + F ++P G+I + G + Sbjct: 249 VVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGEL 308 Query: 309 DFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSPLSTV 368 DFEE+ +YEIQV A DKG P M+ H VL+E++D+NDNVPE+++ SLSLPV ED+ + TV Sbjct: 309 DFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTV 368 Query: 369 IALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVVTAR 428 IALISVSDRDSG NGQV CSLTPHVPFKLVST+KNYYSLVLDS LDRESVSAYELVVTAR Sbjct: 369 IALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTAR 428 Query: 429 DGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADAQENA 488 DGGSPSLWATA VSVEVADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSA DADAQ+NA Sbjct: 429 DGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNA 488 Query: 489 LVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548 LVSYSLVERRVGE ALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN Sbjct: 489 LVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548 Query: 549 VTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLS 608 VTLQVFVLDENDNAPALL G GGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLS Sbjct: 549 VTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLS 608 Query: 609 YELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLTATATVLVS 668 YELQP GA IPF VGLYTGEISTTR LDE DAPRHRLLVLVKDHGEP+LT+TATVLVS Sbjct: 609 YELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLVS 668 Query: 669 LVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTALRCSAPPT 728 LVE+GQAPK SS+AS GA PEAALVD+NVYLI+AICAVSSLLVLTLLLYTALRCSAPPT Sbjct: 669 LVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728 Query: 729 EGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSL 776 C PGKPTLVCSSAVGSWSYSQQR+QRVCS E PKTDLMAFSPSL Sbjct: 729 VSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776 >gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo sapiens] Length = 941 Score = 1169 bits (3025), Expect = 0.0 Identities = 605/768 (78%), Positives = 657/768 (85%) Query: 9 PGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68 PG+Q LLLSLLLLAA EVGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFRVAS Sbjct: 9 PGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68 Query: 69 KRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKDIND 128 KRHGDLLEVNLQNGILFVNSRIDRE+LCGRSAECSIHLEVIVDRPLQVFHV+VEVKDIND Sbjct: 69 KRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIND 128 Query: 129 NAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRNDEE 188 N PVF + + +SES S F LEGASDADIG NSLLTY+L E F L +K ++ Sbjct: 129 NPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDK 188 Query: 189 IKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIYK 248 LVL+K L+RE TPK LL+ IDGGKPELTG+ Q++ITVLDVNDN PAF++ YK Sbjct: 189 SILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYK 248 Query: 249 VRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGNI 308 V L EN N T V+ +NA+D DEG+N +I+Y + F ++P G+I + G + Sbjct: 249 VVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGEL 308 Query: 309 DFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSPLSTV 368 DFEE+ +YEIQV A DKG P M+ H VL+E++D+NDNVPE+++ SLSLPV ED+ + TV Sbjct: 309 DFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTV 368 Query: 369 IALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVVTAR 428 IALISVSDRDSG NGQV CSLTPHVPFKLVST+KNYYSLVLDS LDRESVSAYELVVTAR Sbjct: 369 IALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTAR 428 Query: 429 DGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADAQENA 488 DGGSPSLWATA VSVEVADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSA DADAQ+NA Sbjct: 429 DGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNA 488 Query: 489 LVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548 LVSYSLVERRVGE ALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN Sbjct: 489 LVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548 Query: 549 VTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLS 608 VTLQVFVLDENDNAPALL G GGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLS Sbjct: 549 VTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLS 608 Query: 609 YELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLTATATVLVS 668 YELQP GA IPF VGLYTGEISTTR LDE DAPRHRLLVLVKDHGEP+LT+TATVLVS Sbjct: 609 YELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLVS 668 Query: 669 LVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTALRCSAPPT 728 LVE+GQAPK SS+AS GA PEAALVD+NVYLI+AICAVSSLLVLTLLLYTALRCSAPPT Sbjct: 669 LVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728 Query: 729 EGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSL 776 C PGKPTLVCSSAVGSWSYSQQR+QRVCS E PKTDLMAFSPSL Sbjct: 729 VSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776 >gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo sapiens] Length = 686 Score = 804 bits (2077), Expect = 0.0 Identities = 404/534 (75%), Positives = 462/534 (86%) Query: 1 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 M+F+ + G QCLLL LLLLAA +VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 PRLFR+ASK DLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+ Sbjct: 61 PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 Query: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180 VEV+DINDN P+FP+ + + I ESR P S F LEGASDAD+G+NS+LTY L S+EYF L Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180 Query: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240 DVK N ++ K +GL+LKK+L+RE+ P H L +TA DGGKPELTGT QL +TVLDVNDNAP Sbjct: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 Query: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300 FE++ Y+VR+ ENA NGT V+ +NA+D DEG N I+YSFN+ ++A ++ F +D G Sbjct: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300 Query: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360 +I ++GN+DFE+ Y+I ++ATDKG+PPM+ HCTVL+ I+D NDNVPE+ + SLSLPV Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 Query: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420 ED+ TVIALISV+D DSG NGQV CSLTPHVPFKLVSTFKNYYSLVLDS LDRESVSA Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATAS+SVEVAD+NDNAPAF+Q EYTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQ 534 DADAQENALVSYSLVERRVGERALSSY+SVHAESGKVYALQPLDHEELELLQFQ Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQ 534 Score = 162 bits (409), Expect = 2e-39 Identities = 134/438 (30%), Positives = 199/438 (45%), Gaps = 26/438 (5%) Query: 253 ENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGNIDFEE 312 E A +GT V + A DL + + + F S D ++ NG + V ID EE Sbjct: 37 EEAKHGTFVGRI-AQDLGLELAELVPRLFRM-ASKDREDLLEVNLQNGILFVNSRIDREE 94 Query: 313 --SKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSPLSTVIA 370 +S E + + P+ V +E+ DINDN P ++ + + E +V Sbjct: 95 LCGRSAECSIHLEVIVDRPLQVF-HVDVEVRDINDNPPLFPVEEQRVLIYESRLPDSVFP 153 Query: 371 LISVSDRDSGVNGQVTCSLTPHVPF----KLVSTFKNYYSLVLDSPLDRESVSAYELVVT 426 L SD D G N +T L+ F K+ S L+L LDRE A+ L +T Sbjct: 154 LEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIGLLLKKSLDREEAPAHNLFLT 213 Query: 427 ARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADAQE 486 A DGG P L T + V V DVNDNAP F QSEY V + EN G + ++A D D Sbjct: 214 ATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFENADNGTTVIRLNASDRDEGA 273 Query: 487 NALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLG 546 N +SYS + + + S+ +G++ LD E+ L + + A D G PP+ Sbjct: 274 NGAISYSF--NSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQENLYKILIDATDKGHPPMA 331 Query: 547 SNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAW 606 + T+ V +LD+NDN P + + ++S V G V+A + D DSG N Sbjct: 332 GHCTVLVRILDKNDNVPEIALT-------SLSLPVREDAQFGTVIALISVNDLDSGANGQ 384 Query: 607 LSYELQPGTGGARIPFR-VGLYTGEISTT--RALDEVDAPRHRLLVLVKDHGEPSLTATA 663 ++ L P +PF+ V + S ALD + L+V +D G PSL ATA Sbjct: 385 VNCSLTP-----HVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWATA 439 Query: 664 TVLVSLVESGQAPKASSQ 681 ++ V + + A +Q Sbjct: 440 SLSVEVADMNDNAPAFAQ 457 Score = 157 bits (398), Expect = 3e-38 Identities = 126/466 (27%), Positives = 210/466 (45%), Gaps = 19/466 (4%) Query: 230 ITVLDVNDNAPAFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADI 289 + V D+NDN P F +V + E+ ++ A+D D G N + Y ++ + Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180 Query: 290 LSKFHLDPVNGQISV--KGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNV 347 K + D N QI + K ++D EE+ ++ + + ATD G P ++ +L+ ++D+NDN Sbjct: 181 DVKINSDD-NKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNA 239 Query: 348 PELVIQSLSLPVLEDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTF---KNY 404 P + + E++ T + ++ SDRD G NG ++ S V ++ F +N Sbjct: 240 PTFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNT 299 Query: 405 YSLVLDSPLDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFV 464 +V+ LD E + Y++++ A D G P + +V V + D NDN P + + ++ V Sbjct: 300 GEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPV 359 Query: 465 KENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLD 524 +E+ G I +S D D+ N V+ SL V + +S++ + ++ + LD Sbjct: 360 REDAQFGTVIALISVNDLDSGANGQVNCSLTPH-VPFKLVSTFKNYYS----LVLDSALD 414 Query: 525 HEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRS 584 E + + V+ARD G P L + +L V V D NDNAPA P + V + Sbjct: 415 RESVSAYELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPE-------YTVFVKEN 467 Query: 585 VGAGHVVAKVRAVDADSGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPR 644 G + V A DAD+ NA +SY L G R E AL +D Sbjct: 468 NPPGCHIFTVSARDADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEE 527 Query: 645 HRLLVLVKDHGEPSLTATATVLVSLVESGQAPKASSQASAGATGPE 690 LL P +A++ + S +A AG GP+ Sbjct: 528 LELLQFQPRQPNPDWRYSASLRAGMHSSVHLEEAGI-LRAGPGGPD 572 >gi|14165402 protocadherin alpha 1 isoform 3 precursor [Homo sapiens] Length = 686 Score = 795 bits (2054), Expect = 0.0 Identities = 404/534 (75%), Positives = 462/534 (86%) Query: 1 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 M+FS R GA+ LLL LLLLAA EVGSGQLHYS+ EEAKHGTFVGR+AQDLGLELAELV Sbjct: 1 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60 Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 PRLFRVASK H DLLEVNLQNGILFVNSRIDREELC SAECSIHLE+I DRPLQVFHVE Sbjct: 61 PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120 Query: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180 V+VKDINDN PVF + +FI ESR SRF +EGA+DADIG N+LLTY+L ++YF+L Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180 Query: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240 DV+ +DE KSL L L+K L+RE+TP+ +LL+TA DGGKPEL GT +L ITVLDVNDNAP Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240 Query: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300 F++ +Y+V LLE NGTLV T+NA+D DEGVN ++ +SF++ +S DI KF +D +G Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300 Query: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360 +I + +D+EE+KSYEIQV+A DKG+PPMS+HC VL++++D+NDN PEL + SL LP+ Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360 Query: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420 ED+PLSTVIALI+VSDRDSG NGQVTCSL PHVPFKLVSTFKNYYSLVLDS LDRES+S Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420 Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATA VSVEVADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQ 534 DADAQENALVSYSLVERRVGERALS+YVSVHAESGKVYALQPLDHEELELLQFQ Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQ 534 Score = 151 bits (381), Expect = 3e-36 Identities = 142/448 (31%), Positives = 202/448 (45%), Gaps = 46/448 (10%) Query: 253 ENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPV-----NGQISVKGN 307 E A +GT V V A DL + + + F + SK H D + NG + V Sbjct: 37 EEAKHGTFVGRV-AQDLGLELAELVPRLFR------VASKTHRDLLEVNLQNGILFVNSR 89 Query: 308 IDFEE----SKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDS 363 ID EE S I +E P H V ++ DINDN P + + + E Sbjct: 90 IDREELCQWSAECSIHLELI-ADRPLQVFHVEV--KVKDINDNPPVFRGREQIIFIPESR 146 Query: 364 PLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYS----LVLDSPLDRESVS 419 L++ + +D D G N +T +L+P F L + S L L LDRE Sbjct: 147 LLNSRFPIEGAADADIGANALLTYTLSPSDYFSLDVEASDELSKSLWLELRKYLDREETP 206 Query: 420 AYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSA 479 L++TA DGG P L T + + V DVNDNAP F Q+ Y V + E G + T++A Sbjct: 207 ELHLLLTATDGGKPELQGTVELLITVLDVNDNAPLFDQAVYRVHLLETTANGTLVTTLNA 266 Query: 480 RDADAQENALVSYSL---VERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVS 536 DAD N V +S + R + E+ V + SG++ + LD+EE + + QV Sbjct: 267 SDADEGVNGEVVFSFDSGISRDIQEK-----FKVDSSSGEIRLIDKLDYEETKSYEIQVK 321 Query: 537 ARDAGVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRA 596 A D G PP+ ++ + V VLD NDNAP L V + + E P S V+A + Sbjct: 322 AVDKGSPPMSNHCKVLVKVLDVNDNAPEL---AVTSLYLPIREDAPLST----VIALITV 374 Query: 597 VDADSGYNAWLSYELQPGTGGARIPFR-VGLYTGEISTT--RALDEVDAPRHRLLVLVKD 653 D DSG N ++ L P +PF+ V + S ALD + L+V +D Sbjct: 375 SDRDSGANGQVTCSLMP-----HVPFKLVSTFKNYYSLVLDSALDRESLSVYELVVTARD 429 Query: 654 HGEPSLTATATVLVSLVESGQAPKASSQ 681 G PSL ATA V V + + A +Q Sbjct: 430 GGSPSLWATARVSVEVADVNDNAPAFAQ 457 Score = 150 bits (378), Expect = 6e-36 Identities = 132/473 (27%), Positives = 209/473 (44%), Gaps = 29/473 (6%) Query: 228 LKITVLDVNDNAPAFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYS------F 281 +++ V D+NDN P F + + E+ + A D D G N + Y+ F Sbjct: 119 VEVKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYF 178 Query: 282 NTDMSA-DILSKFHLDPVNGQISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEI 340 + D+ A D LSK + + ++ +D EE+ + + ATD G P + +L+ + Sbjct: 179 SLDVEASDELSK------SLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITV 232 Query: 341 VDINDNVPELVIQSLSLPVLEDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVST 400 +D+NDN P + +LE + T++ ++ SD D GVNG+V S + + Sbjct: 233 LDVNDNAPLFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEK 292 Query: 401 FKNYYS---LVLDSPLDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQ 457 FK S + L LD E +YE+ V A D GSP + V V+V DVNDNAP + Sbjct: 293 FKVDSSSGEIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAV 352 Query: 458 SEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERALSSYVSVHAESGKV 517 + + ++E+ P I ++ D D+ N V+ SL+ V + +S++ + ++ + Sbjct: 353 TSLYLPIREDAPLSTVIALITVSDRDSGANGQVTCSLMPH-VPFKLVSTFKNYYS----L 407 Query: 518 YALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAV 577 LD E L + + V+ARD G P L + + V V D NDNAPA P Sbjct: 408 VLDSALDRESLSVYELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPE-------Y 460 Query: 578 SELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRAL 637 + V + G + V A DAD+ NA +SY L G R E AL Sbjct: 461 TVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYAL 520 Query: 638 DEVDAPRHRLLVLVKDHGEPSLTATATVLVSLVESGQAPKASSQASAGATGPE 690 +D LL P +A++ + S +A AG GP+ Sbjct: 521 QPLDHEELELLQFQPRQPNPDWRYSASLRAGMHSSVHLEEAGI-LRAGPGGPD 572 >gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo sapiens] Length = 685 Score = 774 bits (1998), Expect = 0.0 Identities = 396/525 (75%), Positives = 443/525 (84%) Query: 10 GAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69 G QCLLLSLLLLAA EVGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLFRVASK Sbjct: 9 GVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASK 68 Query: 70 RHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKDINDN 129 RHGDLLEVNLQNGILFVNSRIDREELCGRS ECSIHLEVIVDRPLQVFHV+VEVKDINDN Sbjct: 69 RHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDN 128 Query: 130 APVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRNDEEI 189 P F + + L I ESR SRF LEGASDAD+G N+LLTY L EYF LD+ ++ Sbjct: 129 PPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKD 188 Query: 190 KSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIYKV 249 K LVL+K L+RE+ P+ LL+TA DGGKPE TG+ L I VLD NDNAP F+R +Y+V Sbjct: 189 KFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEV 248 Query: 250 RLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGNID 309 ++ EN N TLV+ +NA+D DEG+NK++ YSF++ + I KF ++ G+I V ID Sbjct: 249 KMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAID 308 Query: 310 FEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSPLSTVI 369 FE+S +YEI V+ TDKGNPPM HCTVL+E++D NDN PE+++ SLSLPV ED+ + TVI Sbjct: 309 FEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVI 368 Query: 370 ALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVVTARD 429 ALISVSD DSG NGQVTCSLTPHVPFKLVST+KNYYSLVLDS LDRE VSAYELVVTARD Sbjct: 369 ALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARD 428 Query: 430 GGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADAQENAL 489 GGSP LWATASVSVEVADVNDNAPAF+QSEYTVFVKENNPPGCHIFTVSA DADAQENAL Sbjct: 429 GGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENAL 488 Query: 490 VSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQ 534 VSYSLVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQ Sbjct: 489 VSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQ 533 Score = 142 bits (357), Expect = 2e-33 Identities = 127/468 (27%), Positives = 207/468 (44%), Gaps = 23/468 (4%) Query: 230 ITVLDVNDNAPAFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSF--NTDMSA 287 + V D+NDN P F T K+ + E+ + A+D D G N + Y N Sbjct: 120 VEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVL 179 Query: 288 DILSKFHLD--PVNGQISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDIND 345 DI++K D PV + ++ +D EE+ ++ + ATD G P + ++L+ ++D ND Sbjct: 180 DIINKKDKDKFPV---LVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDAND 236 Query: 346 NVPELVIQSLSLPVLEDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTF---K 402 N P + + E+ T++ ++ SD D G+N ++ S + VP + F + Sbjct: 237 NAPIFDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINE 296 Query: 403 NYYSLVLDSPLDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTV 462 + ++ +D E + YE+ V D G+P + +V VE+ D NDN+P + ++ Sbjct: 297 RTGEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSL 356 Query: 463 FVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQP 522 VKE+ G I +S D D+ N V+ SL V + +S+Y + ++ + Sbjct: 357 PVKEDAQVGTVIALISVSDHDSGANGQVTCSLTPH-VPFKLVSTYKNYYS----LVLDSA 411 Query: 523 LDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVP 582 LD E + + V+ARD G PPL + ++ V V D NDNAPA + V Sbjct: 412 LDRERVSAYELVVTARDGGSPPLWATASVSVEVADVNDNAPAFAQ-------SEYTVFVK 464 Query: 583 RSVGAGHVVAKVRAVDADSGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDA 642 + G + V A DAD+ NA +SY L G R E AL +D Sbjct: 465 ENNPPGCHIFTVSAWDADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDH 524 Query: 643 PRHRLLVLVKDHGEPSLTATATVLVSLVESGQAPKASSQASAGATGPE 690 LL P +A++ + S +A AG GP+ Sbjct: 525 EELELLQFQPRQPNPDWRYSASLRAGMHSSVHLEEAGI-LRAGPGGPD 571 >gi|14277677 protocadherin gamma subfamily C, 3 isoform 2 precursor [Homo sapiens] Length = 863 Score = 614 bits (1584), Expect = e-176 Identities = 319/698 (45%), Positives = 453/698 (64%), Gaps = 8/698 (1%) Query: 18 LLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGDLLEV 77 LLLL A S +HY + EE + G VG + +LGL+L L R FRV S EV Sbjct: 20 LLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFEV 79 Query: 78 NLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKDINDNAPVFPMAV 137 N + G +FVN R+DREELCG C++ LE++V+ PL++F VEV ++DINDN P FP Sbjct: 80 NRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQE 139 Query: 138 KNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRNDEEIKSLGLVLK 197 L ISE+ PG+RF LE A D D+G+NSL TY L EYF L V+ ++ K LVL+ Sbjct: 140 MKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVLE 199 Query: 198 KNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIYKVRLLENAPN 257 + L+RE P L++TA+DGG P L+ + + I VLD NDNAP F +++Y+ R+LE+AP+ Sbjct: 200 RALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAPS 259 Query: 258 GTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGNIDFEESKSYE 317 GT VV V ATDLDEG N +I YSF + A + F LD V G +++KG +DFE++K +E Sbjct: 260 GTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLHE 319 Query: 318 IQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSPLSTVIALISVSDR 377 I ++A DKG P HC VL+E+VD+NDN PE+ + S+ PV ED+PL TVIAL+SV+D Sbjct: 320 IYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTDL 379 Query: 378 DSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVVTARDGGSPSLWA 437 D+G NG VTC + P +PF L S+ KNY++L + LDRE+V Y L +TARD G+PSL A Sbjct: 380 DAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLSA 439 Query: 438 TASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVER 497 V V+V+D+NDN P SQS Y V+++ENN PG I +S D DA +NA +S+ L+E+ Sbjct: 440 LTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLEQ 499 Query: 498 RVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLD 557 + Y +++ ++G V +L PLD+E+ + D G P L +N+++ +FV D Sbjct: 500 GAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVTD 559 Query: 558 ENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPGTGG 617 NDNAP +L PR GG+ E++PR AGH+V++V DAD+G+NAWLSY L Sbjct: 560 RNDNAPQVLYPRP---GGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSPNQ 616 Query: 618 ARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLTATATVLVSLVESGQAPK 677 + F +GL+TG+IST R + + D+PR L VL+KD+GEPSL+ TAT+ VS+ E +P+ Sbjct: 617 SL--FAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTE--DSPE 672 Query: 678 ASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTL 715 A ++ +G + P ++ YL++++ VS V+T+ Sbjct: 673 ARAEFPSG-SAPREQKKNLTFYLLLSLILVSVGFVVTV 709 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.133 0.381 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 31,653,232 Number of Sequences: 37866 Number of extensions: 1438147 Number of successful extensions: 10358 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 188 Number of HSP's successfully gapped in prelim test: 20 Number of HSP's that attempted gapping in prelim test: 3218 Number of HSP's gapped (non-prelim): 733 length of query: 824 length of database: 18,247,518 effective HSP length: 111 effective length of query: 713 effective length of database: 14,044,392 effective search space: 10013651496 effective search space used: 10013651496 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.