Search of human proteins with 14165405

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo
sapiens]
         (824 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo sapi...  1599   0.0  
gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens]  1548   0.0  
gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo sapi...  1237   0.0  
gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens]  1236   0.0  
gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo sapi...  1232   0.0  
gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens]  1232   0.0  
gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo sapi...  1228   0.0  
gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens]  1226   0.0  
gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo sap...  1209   0.0  
gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo sapi...  1207   0.0  
gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo sapi...  1198   0.0  
gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens]  1197   0.0  
gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens]  1196   0.0  
gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapi...  1195   0.0  
gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo sap...  1193   0.0  
gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo sapi...  1189   0.0  
gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens]  1187   0.0  
gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo sapi...  1187   0.0  
gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo sapi...  1179   0.0  
gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens]  1179   0.0  
gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo sap...  1176   0.0  
gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo sapi...  1176   0.0  
gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens]  1174   0.0  
gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo sapi...  1170   0.0  
gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo sap...  1169   0.0  
gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo sapi...  1167   0.0  
gi|14165402 protocadherin alpha 1 isoform 3 precursor [Homo sapi...   817   0.0  
gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo sap...   783   0.0  
gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo sapi...   780   0.0  
gi|14277677 protocadherin gamma subfamily C, 3 isoform 2 precurs...   595   e-170

>gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo
           sapiens]
          Length = 824

 Score = 1599 bits (4141), Expect = 0.0
 Identities = 824/824 (100%), Positives = 824/824 (100%)

Query: 1   MASSIRRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELV 60
           MASSIRRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELV
Sbjct: 1   MASSIRRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELV 60

Query: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVE 120
           PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVE
Sbjct: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVE 120

Query: 121 VEVKDINDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFL 180
           VEVKDINDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFL
Sbjct: 121 VEVKDINDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFL 180

Query: 181 DIQANDELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEP 240
           DIQANDELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEP
Sbjct: 181 DIQANDELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEP 240

Query: 241 TFAQSVYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISG 300
           TFAQSVYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISG
Sbjct: 241 TFAQSVYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISG 300

Query: 301 EIRTKGKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPIS 360
           EIRTKGKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPIS
Sbjct: 301 EIRTKGKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPIS 360

Query: 361 ENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420
           ENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA
Sbjct: 361 ENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480
           YELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW
Sbjct: 421 YELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480

Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 540
           DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA
Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALT 660

Query: 661 ATATVLVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTA 720
           ATATVLVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTA 720

Query: 721 LRCSVPPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP 780
           LRCSVPPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP
Sbjct: 721 LRCSVPPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP 780

Query: 781 DSAEEKQLSESEYVGKVSLLLFLANSKIVLFKKFYMISTSYLDS 824
           DSAEEKQLSESEYVGKVSLLLFLANSKIVLFKKFYMISTSYLDS
Sbjct: 781 DSAEEKQLSESEYVGKVSLLLFLANSKIVLFKKFYMISTSYLDS 824


>gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens]
          Length = 948

 Score = 1548 bits (4008), Expect = 0.0
 Identities = 796/796 (100%), Positives = 796/796 (100%)

Query: 1   MASSIRRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELV 60
           MASSIRRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELV
Sbjct: 1   MASSIRRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELV 60

Query: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVE 120
           PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVE
Sbjct: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVE 120

Query: 121 VEVKDINDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFL 180
           VEVKDINDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFL
Sbjct: 121 VEVKDINDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFL 180

Query: 181 DIQANDELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEP 240
           DIQANDELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEP
Sbjct: 181 DIQANDELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEP 240

Query: 241 TFAQSVYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISG 300
           TFAQSVYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISG
Sbjct: 241 TFAQSVYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISG 300

Query: 301 EIRTKGKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPIS 360
           EIRTKGKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPIS
Sbjct: 301 EIRTKGKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPIS 360

Query: 361 ENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420
           ENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA
Sbjct: 361 ENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480
           YELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW
Sbjct: 421 YELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480

Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 540
           DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA
Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALT 660

Query: 661 ATATVLVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTA 720
           ATATVLVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTA 720

Query: 721 LRCSVPPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP 780
           LRCSVPPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP
Sbjct: 721 LRCSVPPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP 780

Query: 781 DSAEEKQLSESEYVGK 796
           DSAEEKQLSESEYVGK
Sbjct: 781 DSAEEKQLSESEYVGK 796


>gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo
           sapiens]
          Length = 798

 Score = 1237 bits (3201), Expect = 0.0
 Identities = 633/785 (80%), Positives = 688/785 (87%), Gaps = 1/785 (0%)

Query: 15  LLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDL 74
           LL LLLLAAWE G+GQL YSV EEAKHGTFVGRIAQDLGLEL ELVPRLFRVASK  G L
Sbjct: 15  LLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGGL 74

Query: 75  LEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDNPPIFP 134
           LEVNLQNGILFVNSRIDREELC RSAECSIH+EVIVDRPLQVFHV+VEV+DINDNPP+FP
Sbjct: 75  LEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPVFP 134

Query: 135 MTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELSESLSL 194
            T K +   ESR LDSRFPLEGASDADIG NALL+Y+LS +E+F L+   +DEL + L L
Sbjct: 135 ATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKGLGL 194

Query: 195 VLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLEN 254
           +L KSLDREE  E+ L+L ATDGGKPELTGTVQ+LI VLD NDN P F +++YKV+LLEN
Sbjct: 195 ILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRLLEN 254

Query: 255 TANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAK 314
             NGTLV+KLNASD DEG N +IVYS  +D+S  +++KF IDPI+G+I  KG +D+EE+K
Sbjct: 255 VPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFEESK 314

Query: 315 SYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITV 374
           SYEI V   DKG   +SGHC++ +++ D NDN P++   SLSLPI E+A LGTVIALI+V
Sbjct: 315 SYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTVIALISV 374

Query: 375 SDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434
           SD+D G NG VTCSLT HVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS
Sbjct: 375 SDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434

Query: 435 LWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494
           LWAT SVS+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL
Sbjct: 435 LWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494

Query: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVF 554
           VERRVGERALSSYVSVHAESGKVYALQPLDHEE+ELLQFQV+ARDAGVPPLGSNVTLQVF
Sbjct: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGSNVTLQVF 554

Query: 555 VLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLG 614
           VLDENDNAPALLAPRAG   GAVSELVPWSVG GHVVAKVRAVDADSGYNAWLSYELQ G
Sbjct: 555 VLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWLSYELQPG 614

Query: 615 TGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674
           TG ARIPFRVGLYTGEISTTRALDE D+PRHRLLVLVKDHGEPALTATATVLVSLVESGQ
Sbjct: 615 TGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674

Query: 675 APKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTEGARAP 734
           APKASSRA VGA G +A LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS  PTEGA AP
Sbjct: 675 APKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTEGACAP 734

Query: 735 GKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAEEKQLSESEYV 794
           GKPTLVCSSAVGSWSYSQQRR RVCSGE PPKTDLMAFSPSL    D  ++ Q +E  + 
Sbjct: 735 GKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSRDREDQLQTTEESF- 793

Query: 795 GKVSL 799
            KVS+
Sbjct: 794 AKVSV 798


>gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens]
          Length = 947

 Score = 1236 bits (3199), Expect = 0.0
 Identities = 630/779 (80%), Positives = 684/779 (87%)

Query: 15  LLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDL 74
           LL LLLLAAWE G+GQL YSV EEAKHGTFVGRIAQDLGLEL ELVPRLFRVASK  G L
Sbjct: 15  LLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGGL 74

Query: 75  LEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDNPPIFP 134
           LEVNLQNGILFVNSRIDREELC RSAECSIH+EVIVDRPLQVFHV+VEV+DINDNPP+FP
Sbjct: 75  LEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPVFP 134

Query: 135 MTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELSESLSL 194
            T K +   ESR LDSRFPLEGASDADIG NALL+Y+LS +E+F L+   +DEL + L L
Sbjct: 135 ATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKGLGL 194

Query: 195 VLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLEN 254
           +L KSLDREE  E+ L+L ATDGGKPELTGTVQ+LI VLD NDN P F +++YKV+LLEN
Sbjct: 195 ILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRLLEN 254

Query: 255 TANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAK 314
             NGTLV+KLNASD DEG N +IVYS  +D+S  +++KF IDPI+G+I  KG +D+EE+K
Sbjct: 255 VPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFEESK 314

Query: 315 SYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITV 374
           SYEI V   DKG   +SGHC++ +++ D NDN P++   SLSLPI E+A LGTVIALI+V
Sbjct: 315 SYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTVIALISV 374

Query: 375 SDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434
           SD+D G NG VTCSLT HVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS
Sbjct: 375 SDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434

Query: 435 LWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494
           LWAT SVS+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL
Sbjct: 435 LWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494

Query: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVF 554
           VERRVGERALSSYVSVHAESGKVYALQPLDHEE+ELLQFQV+ARDAGVPPLGSNVTLQVF
Sbjct: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGSNVTLQVF 554

Query: 555 VLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLG 614
           VLDENDNAPALLAPRAG   GAVSELVPWSVG GHVVAKVRAVDADSGYNAWLSYELQ G
Sbjct: 555 VLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWLSYELQPG 614

Query: 615 TGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674
           TG ARIPFRVGLYTGEISTTRALDE D+PRHRLLVLVKDHGEPALTATATVLVSLVESGQ
Sbjct: 615 TGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674

Query: 675 APKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTEGARAP 734
           APKASSRA VGA G +A LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS  PTEGA AP
Sbjct: 675 APKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTEGACAP 734

Query: 735 GKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAEEKQLSESEY 793
           GKPTLVCSSAVGSWSYSQQRR RVCSGE PPKTDLMAFSPSL    D  ++ Q +E  +
Sbjct: 735 GKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSRDREDQLQTTEESF 793


>gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 807

 Score = 1232 bits (3187), Expect = 0.0
 Identities = 638/791 (80%), Positives = 687/791 (86%)

Query: 1   MASSIRRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELV 60
           M  S R G GA   LL LLLLAAWEVGSGQL YS+PEEAKHGTFVGR+AQDLGLEL ELV
Sbjct: 1   MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60

Query: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVE 120
           PRLFRVASK H DLLEVNLQNGILFVNSRIDREELC  SAECSIH+E+I DRPLQVFHVE
Sbjct: 61  PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120

Query: 121 VEVKDINDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFL 180
           V+VKDINDNPP+F    + I  PESRLL+SRFP+EGA+DADIG NALL+Y LS S++F L
Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180

Query: 181 DIQANDELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEP 240
           D++A+DELS+SL L L K LDREET E++LLL ATDGGKPEL GTV++LI VLDVNDN P
Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240

Query: 241 TFAQSVYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISG 300
            F Q+VY+V LLE TANGTLV  LNASDADEG N E+V+S  S +S  IQ KF +D  SG
Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300

Query: 301 EIRTKGKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPIS 360
           EIR   KLDYEE KSYEIQV A DKG+P MS HCK+ +K++D+NDN PE+++TSL LPI 
Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360

Query: 361 ENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420
           E+A L TVIALITVSDRDSG NG VTCSL PHVPFKLVSTFKNYYSLVLDSALDRES+S 
Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420

Query: 421 YELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480
           YELVVTARDGGSPSLWAT  VS+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA 
Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 540
           DADAQENALVSYSLVERRVGERALS+YVSVHAESGKVYALQPLDHEE+ELLQFQVSARDA
Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALLAPR G   GAVSELVP  VGAGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQ   G ARIPFRVGLYTGEISTTR LDEAD  R+RLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT 660

Query: 661 ATATVLVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTA 720
           ATATVLVSLVESGQAPKASSRA VG AG EA LVDVNVYLIIAICAVSSLLVLT+LLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSVPPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP 780
           LRCSVPPTEGA  PGKPTLVCSSA+GSWS SQQRRQRVCS E PPKTDLMAFSP LS   
Sbjct: 721 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL 780

Query: 781 DSAEEKQLSES 791
           +++E  +  E+
Sbjct: 781 NTSERNEQPEA 791


>gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score = 1232 bits (3187), Expect = 0.0
 Identities = 638/791 (80%), Positives = 687/791 (86%)

Query: 1   MASSIRRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELV 60
           M  S R G GA   LL LLLLAAWEVGSGQL YS+PEEAKHGTFVGR+AQDLGLEL ELV
Sbjct: 1   MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60

Query: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVE 120
           PRLFRVASK H DLLEVNLQNGILFVNSRIDREELC  SAECSIH+E+I DRPLQVFHVE
Sbjct: 61  PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120

Query: 121 VEVKDINDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFL 180
           V+VKDINDNPP+F    + I  PESRLL+SRFP+EGA+DADIG NALL+Y LS S++F L
Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180

Query: 181 DIQANDELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEP 240
           D++A+DELS+SL L L K LDREET E++LLL ATDGGKPEL GTV++LI VLDVNDN P
Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240

Query: 241 TFAQSVYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISG 300
            F Q+VY+V LLE TANGTLV  LNASDADEG N E+V+S  S +S  IQ KF +D  SG
Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300

Query: 301 EIRTKGKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPIS 360
           EIR   KLDYEE KSYEIQV A DKG+P MS HCK+ +K++D+NDN PE+++TSL LPI 
Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360

Query: 361 ENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420
           E+A L TVIALITVSDRDSG NG VTCSL PHVPFKLVSTFKNYYSLVLDSALDRES+S 
Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420

Query: 421 YELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480
           YELVVTARDGGSPSLWAT  VS+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA 
Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 540
           DADAQENALVSYSLVERRVGERALS+YVSVHAESGKVYALQPLDHEE+ELLQFQVSARDA
Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALLAPR G   GAVSELVP  VGAGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQ   G ARIPFRVGLYTGEISTTR LDEAD  R+RLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT 660

Query: 661 ATATVLVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTA 720
           ATATVLVSLVESGQAPKASSRA VG AG EA LVDVNVYLIIAICAVSSLLVLT+LLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSVPPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP 780
           LRCSVPPTEGA  PGKPTLVCSSA+GSWS SQQRRQRVCS E PPKTDLMAFSP LS   
Sbjct: 721 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL 780

Query: 781 DSAEEKQLSES 791
           +++E  +  E+
Sbjct: 781 NTSERNEQPEA 791


>gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo
           sapiens]
          Length = 824

 Score = 1228 bits (3178), Expect = 0.0
 Identities = 638/800 (79%), Positives = 691/800 (86%), Gaps = 2/800 (0%)

Query: 1   MASSIRRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELV 60
           M  S R   GA   LLSLLLLAA EVGSGQL YSV EEAKHGTFVGRIAQDLGLEL ELV
Sbjct: 1   MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVE 120
           PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIH+EVIVDRPLQVFHVE
Sbjct: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120

Query: 121 VEVKDINDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFL 180
           VEVKDINDN P+FPM VK +   ESR   SRF LEGASDADIG N+LL+Y L S+E+F L
Sbjct: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180

Query: 181 DIQANDELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEP 240
           D++ NDE  +SL LVL K+L+RE+T +  LL+ A DGGKPELTGT Q+ I VLDVNDN P
Sbjct: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240

Query: 241 TFAQSVYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISG 300
            F +++YKV+LLEN  NGTLVV +NA+D DEG N +I YS  +D+S+ I +KF +DP++G
Sbjct: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300

Query: 301 EIRTKGKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPIS 360
           +I  KG +D+EE+KSYEIQV ATDKG P MS HC + L++VDINDN PE+ I SLSLP+ 
Sbjct: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360

Query: 361 ENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420
           E++ L TVIALI+VSDRDSG NG VTCSLTPHVPFKLVSTFKNYYSLVLDS LDRESVSA
Sbjct: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480
           YELVVTARDGGSPSLWAT SVS+EVADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSA 
Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 540
           DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDA
Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL PR G   GAVSELVP SVGAGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQ GTG ARIPFRVGLYTGEISTTRALDE D+PRHRLLVLVKDHGEP+LT
Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660

Query: 661 ATATVLVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTA 720
           ATATVLVSLVESGQAPKASS+A  GA G EA LVDVNVYLI+AICAVSSLLVLT+LLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSVPPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP 780
           LRCS PPTEG   PGKPTLVCSSAVGSWSYSQQR+QRVCSGE  PKTDLMAFSPSL   P
Sbjct: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780

Query: 781 DS--AEEKQLSESEYVGKVS 798
            S   EEKQ  + +   KVS
Sbjct: 781 ISRDREEKQDVDVDLSAKVS 800


>gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score = 1226 bits (3172), Expect = 0.0
 Identities = 635/789 (80%), Positives = 686/789 (86%), Gaps = 2/789 (0%)

Query: 1   MASSIRRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELV 60
           M  S R   GA   LLSLLLLAA EVGSGQL YSV EEAKHGTFVGRIAQDLGLEL ELV
Sbjct: 1   MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVE 120
           PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIH+EVIVDRPLQVFHVE
Sbjct: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120

Query: 121 VEVKDINDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFL 180
           VEVKDINDN P+FPM VK +   ESR   SRF LEGASDADIG N+LL+Y L S+E+F L
Sbjct: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180

Query: 181 DIQANDELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEP 240
           D++ NDE  +SL LVL K+L+RE+T +  LL+ A DGGKPELTGT Q+ I VLDVNDN P
Sbjct: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240

Query: 241 TFAQSVYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISG 300
            F +++YKV+LLEN  NGTLVV +NA+D DEG N +I YS  +D+S+ I +KF +DP++G
Sbjct: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300

Query: 301 EIRTKGKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPIS 360
           +I  KG +D+EE+KSYEIQV ATDKG P MS HC + L++VDINDN PE+ I SLSLP+ 
Sbjct: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360

Query: 361 ENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420
           E++ L TVIALI+VSDRDSG NG VTCSLTPHVPFKLVSTFKNYYSLVLDS LDRESVSA
Sbjct: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480
           YELVVTARDGGSPSLWAT SVS+EVADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSA 
Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 540
           DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDA
Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL PR G   GAVSELVP SVGAGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQ GTG ARIPFRVGLYTGEISTTRALDE D+PRHRLLVLVKDHGEP+LT
Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660

Query: 661 ATATVLVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTA 720
           ATATVLVSLVESGQAPKASS+A  GA G EA LVDVNVYLI+AICAVSSLLVLT+LLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSVPPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP 780
           LRCS PPTEG   PGKPTLVCSSAVGSWSYSQQR+QRVCSGE  PKTDLMAFSPSL   P
Sbjct: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780

Query: 781 DS--AEEKQ 787
            S   EEKQ
Sbjct: 781 ISRDREEKQ 789


>gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo
           sapiens]
          Length = 807

 Score = 1209 bits (3127), Expect = 0.0
 Identities = 630/801 (78%), Positives = 688/801 (85%), Gaps = 2/801 (0%)

Query: 1   MASSIRRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELV 60
           M SS + G      LL LL+LAAWE GSGQL YSVPEEAKHGTFVGRIAQDLGLEL ELV
Sbjct: 1   MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVE 120
           PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIH+EVIVDRPLQVFHVE
Sbjct: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120

Query: 121 VEVKDINDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFL 180
           V+V+DINDNPPIFP + K I   ESR  ++RFPL+GASDADIGVN+ L+Y+L  +++F L
Sbjct: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180

Query: 181 DIQANDELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEP 240
           D Q + E   SLSLVL K+LDREE  E +LLL A+DGGKPELTGTVQ+LI +LDVNDN P
Sbjct: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240

Query: 241 TFAQSVYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISG 300
            F QSVYKV +LEN  NGTLV+KLNA+D D+G N +IVYS    V   +   FTI+P +G
Sbjct: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300

Query: 301 EIRTKGKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPIS 360
           EIRTKGKLD+EE K YEI V A DKG   M+GHC + ++++D+NDN PEV+ITSLSLPI 
Sbjct: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360

Query: 361 ENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420
           E+     +IALI+VSDRDSG+NG VTC+LTPHVPFKLVST+KNYYSLVLDSALDRESVSA
Sbjct: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480
           YELVVTARDGGSPSLWAT SVS+ VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA 
Sbjct: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480

Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 540
           DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARD+
Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL P AG+A G VSEL+P SVGAGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQL    ARIPFRVGLYTGEISTTR LDE D+P HRLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660

Query: 661 ATATVLVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTA 720
           ATATVL+SLVESGQAP+ASSRA  GA G EA LVDVNVYLIIAICAVSSLLVLT+LLYTA
Sbjct: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSVPPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP 780
           LRCS PPTEGA APGKPTLVCSSA GSWSYSQQRR RVCSGE P KTDLMAFSPSL    
Sbjct: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL 780

Query: 781 DSAE--EKQLSESEYVGKVSL 799
            SAE   ++  +SE + +VSL
Sbjct: 781 GSAEGTGQREEDSECLKEVSL 801


>gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo
           sapiens]
          Length = 950

 Score = 1207 bits (3122), Expect = 0.0
 Identities = 625/784 (79%), Positives = 678/784 (86%)

Query: 1   MASSIRRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELV 60
           M SS + G      LL LL+LAAWE GSGQL YSVPEEAKHGTFVGRIAQDLGLEL ELV
Sbjct: 1   MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVE 120
           PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIH+EVIVDRPLQVFHVE
Sbjct: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120

Query: 121 VEVKDINDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFL 180
           V+V+DINDNPPIFP + K I   ESR  ++RFPL+GASDADIGVN+ L+Y+L  +++F L
Sbjct: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180

Query: 181 DIQANDELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEP 240
           D Q + E   SLSLVL K+LDREE  E +LLL A+DGGKPELTGTVQ+LI +LDVNDN P
Sbjct: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240

Query: 241 TFAQSVYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISG 300
            F QSVYKV +LEN  NGTLV+KLNA+D D+G N +IVYS    V   +   FTI+P +G
Sbjct: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300

Query: 301 EIRTKGKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPIS 360
           EIRTKGKLD+EE K YEI V A DKG   M+GHC + ++++D+NDN PEV+ITSLSLPI 
Sbjct: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360

Query: 361 ENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420
           E+     +IALI+VSDRDSG+NG VTC+LTPHVPFKLVST+KNYYSLVLDSALDRESVSA
Sbjct: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480
           YELVVTARDGGSPSLWAT SVS+ VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA 
Sbjct: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480

Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 540
           DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARD+
Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL P AG+A G VSEL+P SVGAGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQL    ARIPFRVGLYTGEISTTR LDE D+P HRLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660

Query: 661 ATATVLVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTA 720
           ATATVL+SLVESGQAP+ASSRA  GA G EA LVDVNVYLIIAICAVSSLLVLT+LLYTA
Sbjct: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSVPPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP 780
           LRCS PPTEGA APGKPTLVCSSA GSWSYSQQRR RVCSGE P KTDLMAFSPSL    
Sbjct: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL 780

Query: 781 DSAE 784
            SAE
Sbjct: 781 GSAE 784


>gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo
           sapiens]
          Length = 803

 Score = 1198 bits (3100), Expect = 0.0
 Identities = 618/787 (78%), Positives = 680/787 (86%), Gaps = 4/787 (0%)

Query: 15  LLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDL 74
           LL LLLLAAW+VGSGQL YSVPEEAKHGTFVGRIAQDLGLEL ELVPRLFR+ASK   DL
Sbjct: 15  LLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDREDL 74

Query: 75  LEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDNPPIFP 134
           LEVNLQNGILFVNSRIDREELCGRSAECSIH+EVIVDRPLQVFHV+VEV+DINDNPP+FP
Sbjct: 75  LEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPLFP 134

Query: 135 MTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELSESLSL 194
           +  + +   ESRL DS FPLEGASDAD+G N++L+YKLSSSE+F LD++ N + ++ + L
Sbjct: 135 VEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIGL 194

Query: 195 VLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLEN 254
           +L KSLDREE    NL L ATDGGKPELTGTVQ+L+ VLDVNDN PTF QS Y+V++ EN
Sbjct: 195 LLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFEN 254

Query: 255 TANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAK 314
             NGT V++LNASD DEG N  I YS  S V++ +   F+ID  +GEI  +G LD+E+  
Sbjct: 255 ADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQEN 314

Query: 315 SYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITV 374
            Y+I + ATDKG P M+GHC + ++++D NDN PE+++TSLSLP+ E+A  GTVIALI+V
Sbjct: 315 LYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALISV 374

Query: 375 SDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434
           +D DSG NG V CSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS
Sbjct: 375 NDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434

Query: 435 LWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494
           LWAT S+S+EVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQENALVSYSL
Sbjct: 435 LWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSL 494

Query: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVF 554
           VERRVGERALSSY+SVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLGSNVTLQVF
Sbjct: 495 VERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVF 554

Query: 555 VLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLG 614
           VLDENDNAPALLAPR G   GAVSELVP S+GAG VVAKVRAVDADSGYNAWLSYELQ  
Sbjct: 555 VLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSYELQPP 614

Query: 615 TGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674
             SAR PFRVGLYTGEISTTR LDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ
Sbjct: 615 ASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674

Query: 675 APKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTEGARAP 734
           APKASSRA VGAAG EA LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS PPTEGA   
Sbjct: 675 APKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACTA 734

Query: 735 GKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP---DSAEEKQLSES 791
            KPTLVCSSAVGSWSYSQQRRQRVCSGE PPK DLMAFSPSLS  P     AE + L+E 
Sbjct: 735 DKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAENQDLNE- 793

Query: 792 EYVGKVS 798
           ++  KVS
Sbjct: 794 DHDAKVS 800


>gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score = 1197 bits (3098), Expect = 0.0
 Identities = 615/779 (78%), Positives = 675/779 (86%), Gaps = 3/779 (0%)

Query: 15  LLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDL 74
           LL LLLLAAW+VGSGQL YSVPEEAKHGTFVGRIAQDLGLEL ELVPRLFR+ASK   DL
Sbjct: 15  LLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDREDL 74

Query: 75  LEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDNPPIFP 134
           LEVNLQNGILFVNSRIDREELCGRSAECSIH+EVIVDRPLQVFHV+VEV+DINDNPP+FP
Sbjct: 75  LEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPLFP 134

Query: 135 MTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELSESLSL 194
           +  + +   ESRL DS FPLEGASDAD+G N++L+YKLSSSE+F LD++ N + ++ + L
Sbjct: 135 VEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIGL 194

Query: 195 VLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLEN 254
           +L KSLDREE    NL L ATDGGKPELTGTVQ+L+ VLDVNDN PTF QS Y+V++ EN
Sbjct: 195 LLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFEN 254

Query: 255 TANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAK 314
             NGT V++LNASD DEG N  I YS  S V++ +   F+ID  +GEI  +G LD+E+  
Sbjct: 255 ADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQEN 314

Query: 315 SYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITV 374
            Y+I + ATDKG P M+GHC + ++++D NDN PE+++TSLSLP+ E+A  GTVIALI+V
Sbjct: 315 LYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALISV 374

Query: 375 SDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434
           +D DSG NG V CSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS
Sbjct: 375 NDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434

Query: 435 LWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494
           LWAT S+S+EVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQENALVSYSL
Sbjct: 435 LWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSL 494

Query: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVF 554
           VERRVGERALSSY+SVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLGSNVTLQVF
Sbjct: 495 VERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVF 554

Query: 555 VLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLG 614
           VLDENDNAPALLAPR G   GAVSELVP S+GAG VVAKVRAVDADSGYNAWLSYELQ  
Sbjct: 555 VLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSYELQPP 614

Query: 615 TGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674
             SAR PFRVGLYTGEISTTR LDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ
Sbjct: 615 ASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674

Query: 675 APKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTEGARAP 734
           APKASSRA VGAAG EA LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS PPTEGA   
Sbjct: 675 APKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACTA 734

Query: 735 GKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP---DSAEEKQLSE 790
            KPTLVCSSAVGSWSYSQQRRQRVCSGE PPK DLMAFSPSLS  P     AE + L+E
Sbjct: 735 DKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAENQDLNE 793


>gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens]
          Length = 936

 Score = 1196 bits (3094), Expect = 0.0
 Identities = 618/794 (77%), Positives = 672/794 (84%)

Query: 6   RRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFR 65
           RRG      LL  LLLA W+ GSGQL YS+PEEAKHGTFVGRIAQDLGLEL ELVPRLFR
Sbjct: 5   RRGSLGSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRLFR 64

Query: 66  VASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKD 125
           VASK  GDLLEVNLQNGILFVNSRIDREELC R AECSIH+EVIVDRPLQVFHVEV VKD
Sbjct: 65  VASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKD 124

Query: 126 INDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQAN 185
           INDNPP F    + +   ESR+ DSRFPLEGASD DIG NA L Y+L+ +E+F LD++ N
Sbjct: 125 INDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTN 184

Query: 186 DELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQS 245
           +E +  L LVL KSLDREET E  LL++ATDGGKPELTGTVQ+LI VLD NDN P F +S
Sbjct: 185 EEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKS 244

Query: 246 VYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTK 305
           +Y V+LLEN  +GTLV+KLNASDADEG N EIVY   + V   +++KF I+  +GEI+  
Sbjct: 245 IYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVN 304

Query: 306 GKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASL 365
           G+LDYE+  SYEI + A DK T  +SGHCK+ +KL+D+NDNTPE++IT+L LP+ E+A L
Sbjct: 305 GELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPL 364

Query: 366 GTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVV 425
            TVIALI+VSDRDSG NG VTCSL PHVPFKLVSTFKNYYSLVLDSALDRESVS YELVV
Sbjct: 365 STVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVV 424

Query: 426 TARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQ 485
           TARDGGSPSLWAT SVS+EVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSA DADAQ
Sbjct: 425 TARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQ 484

Query: 486 ENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPL 545
           ENALVSYSLVERRVGER LSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPL
Sbjct: 485 ENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPL 544

Query: 546 GSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNA 605
           GSNVTLQVFVLDENDNAPALL PR G   GAVSELVP SVGAGHVVAKVRAVD DSGYNA
Sbjct: 545 GSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNA 604

Query: 606 WLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATV 665
           WLSYELQ   GSARIPFRVGLYTGEISTTR+LDE ++PRHRLLVLVKDHGEP LTATATV
Sbjct: 605 WLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATATV 664

Query: 666 LVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSV 725
           LVSLVESGQAPKASSRA  GA G EA LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS 
Sbjct: 665 LVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA 724

Query: 726 PPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAEE 785
            PTE     GKPTL+CSSAVGSWSYSQQRRQRVCSGE PPKTDLMAFSPSL QGP S + 
Sbjct: 725 QPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPTSTDN 784

Query: 786 KQLSESEYVGKVSL 799
            +    ++    SL
Sbjct: 785 PRQPNPDWRYSASL 798


>gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo
           sapiens]
          Length = 816

 Score = 1195 bits (3092), Expect = 0.0
 Identities = 616/779 (79%), Positives = 667/779 (85%)

Query: 6   RRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFR 65
           RRG      LL  LLLA W+ GSGQL YS+PEEAKHGTFVGRIAQDLGLEL ELVPRLFR
Sbjct: 5   RRGSLGSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRLFR 64

Query: 66  VASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKD 125
           VASK  GDLLEVNLQNGILFVNSRIDREELC R AECSIH+EVIVDRPLQVFHVEV VKD
Sbjct: 65  VASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKD 124

Query: 126 INDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQAN 185
           INDNPP F    + +   ESR+ DSRFPLEGASD DIG NA L Y+L+ +E+F LD++ N
Sbjct: 125 INDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTN 184

Query: 186 DELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQS 245
           +E +  L LVL KSLDREET E  LL++ATDGGKPELTGTVQ+LI VLD NDN P F +S
Sbjct: 185 EEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKS 244

Query: 246 VYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTK 305
           +Y V+LLEN  +GTLV+KLNASDADEG N EIVY   + V   +++KF I+  +GEI+  
Sbjct: 245 IYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVN 304

Query: 306 GKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASL 365
           G+LDYE+  SYEI + A DK T  +SGHCK+ +KL+D+NDNTPE++IT+L LP+ E+A L
Sbjct: 305 GELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPL 364

Query: 366 GTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVV 425
            TVIALI+VSDRDSG NG VTCSL PHVPFKLVSTFKNYYSLVLDSALDRESVS YELVV
Sbjct: 365 STVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVV 424

Query: 426 TARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQ 485
           TARDGGSPSLWAT SVS+EVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSA DADAQ
Sbjct: 425 TARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQ 484

Query: 486 ENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPL 545
           ENALVSYSLVERRVGER LSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPL
Sbjct: 485 ENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPL 544

Query: 546 GSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNA 605
           GSNVTLQVFVLDENDNAPALL PR G   GAVSELVP SVGAGHVVAKVRAVD DSGYNA
Sbjct: 545 GSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNA 604

Query: 606 WLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATV 665
           WLSYELQ   GSARIPFRVGLYTGEISTTR+LDE ++PRHRLLVLVKDHGEP LTATATV
Sbjct: 605 WLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATATV 664

Query: 666 LVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSV 725
           LVSLVESGQAPKASSRA  GA G EA LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS 
Sbjct: 665 LVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA 724

Query: 726 PPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAE 784
            PTE     GKPTL+CSSAVGSWSYSQQRRQRVCSGE PPKTDLMAFSPSL QGP S +
Sbjct: 725 QPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPTSTD 783


>gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo
           sapiens]
          Length = 810

 Score = 1193 bits (3087), Expect = 0.0
 Identities = 622/797 (78%), Positives = 682/797 (85%), Gaps = 3/797 (0%)

Query: 6   RRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFR 65
           RRG G     L LLLL  WEVGSGQL YSV EEAKHGTFVGRIAQDLGLEL ELV RLFR
Sbjct: 6   RRGLGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFR 65

Query: 66  VASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKD 125
           VASK HGDLLEVNLQNGILFVNSRIDREELCG+SAECSIH+EVIVDRPLQVFHV VEVKD
Sbjct: 66  VASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKD 125

Query: 126 INDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQAN 185
           INDNPP+F +  + +   ES+  DSRFPLEGASDADI  NALL+Y+LS +E+F LD   N
Sbjct: 126 INDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTN 185

Query: 186 DELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQS 245
            +  + LSL+L KSLDRE+T E+NLLL ATDGGKPELTGTV++L++VLDVNDN+P F +S
Sbjct: 186 GKQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKS 245

Query: 246 VYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTK 305
            YKV L+EN A  TLV+KLNA+D DEG N E+ YSL S +    +  FT+D  +GE+R  
Sbjct: 246 EYKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVN 304

Query: 306 GKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASL 365
           G LDYEE K Y+I+V ATDKGTP M+GHC + ++++D NDN+PEV++TSLSLP+ E+A  
Sbjct: 305 GTLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQP 364

Query: 366 GTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVV 425
            TVIALI+VSDRDSG NG VTCSLTPHVPFKLVSTFKNYYSLVLDSALDRE+V AYELVV
Sbjct: 365 STVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVV 424

Query: 426 TARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQ 485
           TARDGGSPSLWAT  VS+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ
Sbjct: 425 TARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQ 484

Query: 486 ENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPL 545
           ENALVSYSLVERR+G+RALSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPL
Sbjct: 485 ENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL 544

Query: 546 GSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNA 605
            SNVTLQVFVLDENDNAPALLA +AG+A GAV++LVP SVGAGHVVAKVRAVDADSGYNA
Sbjct: 545 SSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNA 604

Query: 606 WLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATV 665
           WLSYELQ   G +RIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATV
Sbjct: 605 WLSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATV 664

Query: 666 LVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSV 725
           LVSLVESGQAPKASSR   GAA  EA LVDVNVYLIIAIC VSSLLVLT+LLYTAL  S 
Sbjct: 665 LVSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSA 724

Query: 726 PPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAEE 785
            PTEGA APGKPTLVCS AVGSWSYSQQRRQRVCS E PPKTDLMAFSPSL  G +  EE
Sbjct: 725 TPTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNKEEE 784

Query: 786 KQLSE--SEYVGKVSLL 800
            +  E  S + G+VS L
Sbjct: 785 GERQEPGSNHPGQVSFL 801


>gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo
           sapiens]
          Length = 949

 Score = 1189 bits (3077), Expect = 0.0
 Identities = 617/785 (78%), Positives = 675/785 (85%), Gaps = 1/785 (0%)

Query: 6   RRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFR 65
           RRG G     L LLLL  WEVGSGQL YSV EEAKHGTFVGRIAQDLGLEL ELV RLFR
Sbjct: 6   RRGLGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFR 65

Query: 66  VASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKD 125
           VASK HGDLLEVNLQNGILFVNSRIDREELCG+SAECSIH+EVIVDRPLQVFHV VEVKD
Sbjct: 66  VASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKD 125

Query: 126 INDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQAN 185
           INDNPP+F +  + +   ES+  DSRFPLEGASDADI  NALL+Y+LS +E+F LD   N
Sbjct: 126 INDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTN 185

Query: 186 DELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQS 245
            +  + LSL+L KSLDRE+T E+NLLL ATDGGKPELTGTV++L++VLDVNDN+P F +S
Sbjct: 186 GKQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKS 245

Query: 246 VYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTK 305
            YKV L+EN A  TLV+KLNA+D DEG N E+ YSL S +    +  FT+D  +GE+R  
Sbjct: 246 EYKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVN 304

Query: 306 GKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASL 365
           G LDYEE K Y+I+V ATDKGTP M+GHC + ++++D NDN+PEV++TSLSLP+ E+A  
Sbjct: 305 GTLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQP 364

Query: 366 GTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVV 425
            TVIALI+VSDRDSG NG VTCSLTPHVPFKLVSTFKNYYSLVLDSALDRE+V AYELVV
Sbjct: 365 STVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVV 424

Query: 426 TARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQ 485
           TARDGGSPSLWAT  VS+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ
Sbjct: 425 TARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQ 484

Query: 486 ENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPL 545
           ENALVSYSLVERR+G+RALSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPL
Sbjct: 485 ENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL 544

Query: 546 GSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNA 605
            SNVTLQVFVLDENDNAPALLA +AG+A GAV++LVP SVGAGHVVAKVRAVDADSGYNA
Sbjct: 545 SSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNA 604

Query: 606 WLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATV 665
           WLSYELQ   G +RIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATV
Sbjct: 605 WLSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATV 664

Query: 666 LVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSV 725
           LVSLVESGQAPKASSR   GAA  EA LVDVNVYLIIAIC VSSLLVLT+LLYTAL  S 
Sbjct: 665 LVSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSA 724

Query: 726 PPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAEE 785
            PTEGA APGKPTLVCS AVGSWSYSQQRRQRVCS E PPKTDLMAFSPSL  G +  EE
Sbjct: 725 TPTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNKEEE 784

Query: 786 KQLSE 790
            +  E
Sbjct: 785 GERQE 789


>gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens]
          Length = 937

 Score = 1187 bits (3072), Expect = 0.0
 Identities = 608/785 (77%), Positives = 674/785 (85%)

Query: 15  LLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDL 74
           LL +++LAAWE G GQL YSVPEEAKHG FVGRIAQDLGLEL ELVPRLFR   K  GDL
Sbjct: 15  LLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCKFRGDL 74

Query: 75  LEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDNPPIFP 134
           LEVNLQNGILFVNSRIDREELCGRSAECSIH+EVIV+RPLQVFHV+VEVKDINDNPP+FP
Sbjct: 75  LEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDNPPVFP 134

Query: 135 MTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELSESLSL 194
            T + +   ESR LDSRFPLEGASDADIG NALL+Y+LS +E+FFLD+  +++  + L L
Sbjct: 135 ATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLGL 194

Query: 195 VLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLEN 254
           VL K LDREET E++LLL ATDGGKPELTGTVQ+LI VLD NDN P F +++Y VKL EN
Sbjct: 195 VLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPEN 254

Query: 255 TANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAK 314
            + GTLV+  NASD DEG N +I+YS  SDVS  I++KF +DP+SG I   G +D+EE++
Sbjct: 255 VSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEESR 314

Query: 315 SYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITV 374
           +++I V A DKG P ++GHC + +++VD+NDN P++++TSLSLPI E+A  GTVI LI+V
Sbjct: 315 AHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVITLISV 374

Query: 375 SDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434
            DRD G NG VTCSLTP VPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS
Sbjct: 375 FDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434

Query: 435 LWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494
           LWAT SVS+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NALVSYSL
Sbjct: 435 LWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNALVSYSL 494

Query: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVF 554
           VE RVGERALSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLGSNVTLQVF
Sbjct: 495 VELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVF 554

Query: 555 VLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLG 614
           VLDENDNAPALLAPR G   GAV ELVP SVGAGHVVAKVRAVDADSGYNAWLSYELQ  
Sbjct: 555 VLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPV 614

Query: 615 TGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674
              A IPFRVGLYTGEISTTRALDE D+PRHRLLVLVKDHGEP+LTATATVLVSLVESGQ
Sbjct: 615 AAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSLVESGQ 674

Query: 675 APKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTEGARAP 734
           APKASSRA +G AG E  LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS P +EGA + 
Sbjct: 675 APKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSEGACSL 734

Query: 735 GKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAEEKQLSESEYV 794
            KPTLVCSSAVGSWS+SQQRRQRVCSGE PPKTDLMAFSPSL QGP S +  +    ++ 
Sbjct: 735 VKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTDNPRQPNPDWR 794

Query: 795 GKVSL 799
              SL
Sbjct: 795 YSASL 799


>gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo
           sapiens]
          Length = 789

 Score = 1187 bits (3070), Expect = 0.0
 Identities = 606/770 (78%), Positives = 669/770 (86%)

Query: 15  LLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDL 74
           LL +++LAAWE G GQL YSVPEEAKHG FVGRIAQDLGLEL ELVPRLFR   K  GDL
Sbjct: 15  LLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCKFRGDL 74

Query: 75  LEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDNPPIFP 134
           LEVNLQNGILFVNSRIDREELCGRSAECSIH+EVIV+RPLQVFHV+VEVKDINDNPP+FP
Sbjct: 75  LEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDNPPVFP 134

Query: 135 MTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELSESLSL 194
            T + +   ESR LDSRFPLEGASDADIG NALL+Y+LS +E+FFLD+  +++  + L L
Sbjct: 135 ATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLGL 194

Query: 195 VLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLEN 254
           VL K LDREET E++LLL ATDGGKPELTGTVQ+LI VLD NDN P F +++Y VKL EN
Sbjct: 195 VLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPEN 254

Query: 255 TANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAK 314
            + GTLV+  NASD DEG N +I+YS  SDVS  I++KF +DP+SG I   G +D+EE++
Sbjct: 255 VSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEESR 314

Query: 315 SYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITV 374
           +++I V A DKG P ++GHC + +++VD+NDN P++++TSLSLPI E+A  GTVI LI+V
Sbjct: 315 AHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVITLISV 374

Query: 375 SDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434
            DRD G NG VTCSLTP VPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS
Sbjct: 375 FDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434

Query: 435 LWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494
           LWAT SVS+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NALVSYSL
Sbjct: 435 LWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNALVSYSL 494

Query: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVF 554
           VE RVGERALSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLGSNVTLQVF
Sbjct: 495 VELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVF 554

Query: 555 VLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLG 614
           VLDENDNAPALLAPR G   GAV ELVP SVGAGHVVAKVRAVDADSGYNAWLSYELQ  
Sbjct: 555 VLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPV 614

Query: 615 TGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674
              A IPFRVGLYTGEISTTRALDE D+PRHRLLVLVKDHGEP+LTATATVLVSLVESGQ
Sbjct: 615 AAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSLVESGQ 674

Query: 675 APKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTEGARAP 734
           APKASSRA +G AG E  LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS P +EGA + 
Sbjct: 675 APKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSEGACSL 734

Query: 735 GKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAE 784
            KPTLVCSSAVGSWS+SQQRRQRVCSGE PPKTDLMAFSPSL QGP S +
Sbjct: 735 VKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTD 784


>gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo
           sapiens]
          Length = 814

 Score = 1179 bits (3050), Expect = 0.0
 Identities = 602/783 (76%), Positives = 667/783 (85%), Gaps = 3/783 (0%)

Query: 10  GAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASK 69
           G+W  LL LLLLAAW+VGSGQL YSVPEEAKHGTFVGRIAQDLGLEL ELVPRLFRVASK
Sbjct: 10  GSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69

Query: 70  RHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDN 129
           RH DLLEV+LQNGILFVNSRIDREELCGRSAECSIH+EVIVDRPLQVFHV+VEVKD+NDN
Sbjct: 70  RHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDN 129

Query: 130 PPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELS 189
           PP+F +  + +   ESR+ DSRFPLEGASDAD+G N++L+Y+LSS ++F LD+ + ++ +
Sbjct: 130 PPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDEN 189

Query: 190 ESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKV 249
           + + LVL KSLDRE+    +L L ATDGGKPELTGTVQ+L+ VLDVNDN PTF QS Y+V
Sbjct: 190 KLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249

Query: 250 KLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLD 309
           ++ EN  NGT V+KLNASD DEG N  I YS  S V + +   F+ID  +GEI  +G LD
Sbjct: 250 RIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLD 309

Query: 310 YEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVI 369
           +E+   Y+I + ATDKG P M+GHC + ++++D NDN PE+++TSLSLP+ E+A  GTVI
Sbjct: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369

Query: 370 ALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429
           ALI+V+D DSG NG VTCSL PHVPFKLVSTFKNYYSLVLDSALDRE VSAYELVVTARD
Sbjct: 370 ALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARD 429

Query: 430 GGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENAL 489
           GGSPSLWAT S+S+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQENAL
Sbjct: 430 GGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489

Query: 490 VSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNV 549
           VSYSLVERRVGER+LSSY+SVH ESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLGSNV
Sbjct: 490 VSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549

Query: 550 TLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSY 609
           TLQVFVLDENDNAPALL PR G   GA S+LVP SVGAGHVVAKVRAVDADSGYNAWLSY
Sbjct: 550 TLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609

Query: 610 ELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669
           ELQ    S RIPFRVGLYTGEISTTR LDEADSPRHRLLVLVKDHGEPALTATATVLVSL
Sbjct: 610 ELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669

Query: 670 VESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTE 729
           VESGQAPKASSR   G  G EA LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS  PTE
Sbjct: 670 VESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTE 729

Query: 730 GARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQ---GPDSAEEK 786
           G    GKPTLVCSSAVGSWSYSQQ+ QRVCSGE PPKTDLMAFSP L       D  EE+
Sbjct: 730 GGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVDVGEEQ 789

Query: 787 QLS 789
            L+
Sbjct: 790 DLN 792


>gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score = 1179 bits (3050), Expect = 0.0
 Identities = 602/783 (76%), Positives = 667/783 (85%), Gaps = 3/783 (0%)

Query: 10  GAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASK 69
           G+W  LL LLLLAAW+VGSGQL YSVPEEAKHGTFVGRIAQDLGLEL ELVPRLFRVASK
Sbjct: 10  GSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69

Query: 70  RHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDN 129
           RH DLLEV+LQNGILFVNSRIDREELCGRSAECSIH+EVIVDRPLQVFHV+VEVKD+NDN
Sbjct: 70  RHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDN 129

Query: 130 PPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELS 189
           PP+F +  + +   ESR+ DSRFPLEGASDAD+G N++L+Y+LSS ++F LD+ + ++ +
Sbjct: 130 PPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDEN 189

Query: 190 ESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKV 249
           + + LVL KSLDRE+    +L L ATDGGKPELTGTVQ+L+ VLDVNDN PTF QS Y+V
Sbjct: 190 KLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249

Query: 250 KLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLD 309
           ++ EN  NGT V+KLNASD DEG N  I YS  S V + +   F+ID  +GEI  +G LD
Sbjct: 250 RIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLD 309

Query: 310 YEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVI 369
           +E+   Y+I + ATDKG P M+GHC + ++++D NDN PE+++TSLSLP+ E+A  GTVI
Sbjct: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369

Query: 370 ALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429
           ALI+V+D DSG NG VTCSL PHVPFKLVSTFKNYYSLVLDSALDRE VSAYELVVTARD
Sbjct: 370 ALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARD 429

Query: 430 GGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENAL 489
           GGSPSLWAT S+S+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQENAL
Sbjct: 430 GGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489

Query: 490 VSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNV 549
           VSYSLVERRVGER+LSSY+SVH ESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLGSNV
Sbjct: 490 VSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549

Query: 550 TLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSY 609
           TLQVFVLDENDNAPALL PR G   GA S+LVP SVGAGHVVAKVRAVDADSGYNAWLSY
Sbjct: 550 TLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609

Query: 610 ELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669
           ELQ    S RIPFRVGLYTGEISTTR LDEADSPRHRLLVLVKDHGEPALTATATVLVSL
Sbjct: 610 ELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669

Query: 670 VESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTE 729
           VESGQAPKASSR   G  G EA LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS  PTE
Sbjct: 670 VESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTE 729

Query: 730 GARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQ---GPDSAEEK 786
           G    GKPTLVCSSAVGSWSYSQQ+ QRVCSGE PPKTDLMAFSP L       D  EE+
Sbjct: 730 GGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVDVGEEQ 789

Query: 787 QLS 789
            L+
Sbjct: 790 DLN 792


>gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo
           sapiens]
          Length = 792

 Score = 1176 bits (3043), Expect = 0.0
 Identities = 610/770 (79%), Positives = 662/770 (85%)

Query: 7   RGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRV 66
           RG G+   LLSLLLLAAWEVGSGQL YSV EEAKHGTFVGRIAQDLGLEL ELVPRLFRV
Sbjct: 7   RGPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRV 66

Query: 67  ASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDI 126
           ASKRHGDLLEVNLQNGILFVNSRIDRE+LCGRSAECSIH+EVIVDRPLQVFHV+VEVKDI
Sbjct: 67  ASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDI 126

Query: 127 NDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQAND 186
           NDNPP+F    + +   ES  LDS FPLEGASDADIGVN+LL+Y LS +E F L I+   
Sbjct: 127 NDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKK 186

Query: 187 ELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSV 246
           + S    LVL K LDRE+T ++NLLL+  DGGKPELTG+VQI I VLDVNDN P F +  
Sbjct: 187 DKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPS 246

Query: 247 YKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKG 306
           YKV L EN  N T V++LNASD DEG N EI Y +   +  + +  F+I+P +GEIR  G
Sbjct: 247 YKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYG 306

Query: 307 KLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLG 366
           +LD+EE  +YEIQV A DKG PSM+GH  + ++++D+NDN PEV +TSLSLP+ E+A +G
Sbjct: 307 ELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVG 366

Query: 367 TVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVT 426
           TVIALI+VSDRDSG NG V CSLTPHVPFKLVST+KNYYSLVLDSALDRESVSAYELVVT
Sbjct: 367 TVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVT 426

Query: 427 ARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQE 486
           ARDGGSPSLWAT  VS+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQ+
Sbjct: 427 ARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQK 486

Query: 487 NALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLG 546
           NALVSYSLVERRVGE ALSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLG
Sbjct: 487 NALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLG 546

Query: 547 SNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAW 606
           SNVTLQVFVLDENDNAPALLA  AG+A GAVSELVP SVGAGHVVAKVRAVDADSGYNAW
Sbjct: 547 SNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAW 606

Query: 607 LSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVL 666
           LSYELQ     A IPF VGLYTGEISTTR LDEAD+PRHRLLVLVKDHGEPALT+TATVL
Sbjct: 607 LSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVL 666

Query: 667 VSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVP 726
           VSLVE+GQAPK SSRA VGA   EA LVD+NVYLIIAICAVSSLLVLT+LLYTALRCS P
Sbjct: 667 VSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAP 726

Query: 727 PTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSL 776
           PT    APGKPTLVCSSAVGSWSYSQQRRQRVCS E PPKTDLMAFSPSL
Sbjct: 727 PTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776


>gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo
           sapiens]
          Length = 941

 Score = 1176 bits (3043), Expect = 0.0
 Identities = 610/770 (79%), Positives = 662/770 (85%)

Query: 7   RGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRV 66
           RG G+   LLSLLLLAAWEVGSGQL YSV EEAKHGTFVGRIAQDLGLEL ELVPRLFRV
Sbjct: 7   RGPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRV 66

Query: 67  ASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDI 126
           ASKRHGDLLEVNLQNGILFVNSRIDRE+LCGRSAECSIH+EVIVDRPLQVFHV+VEVKDI
Sbjct: 67  ASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDI 126

Query: 127 NDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQAND 186
           NDNPP+F    + +   ES  LDS FPLEGASDADIGVN+LL+Y LS +E F L I+   
Sbjct: 127 NDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKK 186

Query: 187 ELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSV 246
           + S    LVL K LDRE+T ++NLLL+  DGGKPELTG+VQI I VLDVNDN P F +  
Sbjct: 187 DKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPS 246

Query: 247 YKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKG 306
           YKV L EN  N T V++LNASD DEG N EI Y +   +  + +  F+I+P +GEIR  G
Sbjct: 247 YKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYG 306

Query: 307 KLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLG 366
           +LD+EE  +YEIQV A DKG PSM+GH  + ++++D+NDN PEV +TSLSLP+ E+A +G
Sbjct: 307 ELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVG 366

Query: 367 TVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVT 426
           TVIALI+VSDRDSG NG V CSLTPHVPFKLVST+KNYYSLVLDSALDRESVSAYELVVT
Sbjct: 367 TVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVT 426

Query: 427 ARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQE 486
           ARDGGSPSLWAT  VS+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQ+
Sbjct: 427 ARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQK 486

Query: 487 NALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLG 546
           NALVSYSLVERRVGE ALSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLG
Sbjct: 487 NALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLG 546

Query: 547 SNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAW 606
           SNVTLQVFVLDENDNAPALLA  AG+A GAVSELVP SVGAGHVVAKVRAVDADSGYNAW
Sbjct: 547 SNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAW 606

Query: 607 LSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVL 666
           LSYELQ     A IPF VGLYTGEISTTR LDEAD+PRHRLLVLVKDHGEPALT+TATVL
Sbjct: 607 LSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVL 666

Query: 667 VSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVP 726
           VSLVE+GQAPK SSRA VGA   EA LVD+NVYLIIAICAVSSLLVLT+LLYTALRCS P
Sbjct: 667 VSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAP 726

Query: 727 PTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSL 776
           PT    APGKPTLVCSSAVGSWSYSQQRRQRVCS E PPKTDLMAFSPSL
Sbjct: 727 PTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776


>gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens]
          Length = 842

 Score = 1174 bits (3037), Expect = 0.0
 Identities = 609/805 (75%), Positives = 679/805 (84%), Gaps = 2/805 (0%)

Query: 15  LLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDL 74
           LLSLL+LA W VGSGQL YSVPEEA+HGTFVGRIAQDLGLEL ELVPRLF++ SK  GDL
Sbjct: 15  LLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGRGDL 74

Query: 75  LEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDNPPIFP 134
           LEVNLQNGILFVNSRIDREELCGRSAECSIH+EVIVDRPLQVFHV+VEVKDINDNPP+FP
Sbjct: 75  LEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPPVFP 134

Query: 135 MTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELSESLSL 194
            T K +   ESR LDSRFPLEGASDADIG NALL+Y+LS +E+FFLD+  +++  + L L
Sbjct: 135 ATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLGL 194

Query: 195 VLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLEN 254
           VL K LDREET E++LLL ATDGGKPELTGTVQ+LI VLD NDN P F +++Y VKL EN
Sbjct: 195 VLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPEN 254

Query: 255 TANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAK 314
            + GTLV+  NASD DEG N +I+YS  SDVS  I++KF +DP+SG I   G +D+EE++
Sbjct: 255 VSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEESR 314

Query: 315 SYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITV 374
           +++I V A DKG P ++GHC + +++VD+NDN P+++I +LS+P+ E+A LGTVIALI+V
Sbjct: 315 AHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIALISV 374

Query: 375 SDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434
            D D+  NG VTCSLTPHVPFKLVST+KNYYSLVLD ALDRESVSAYELVVTARDGGSPS
Sbjct: 375 IDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGGSPS 434

Query: 435 LWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494
           LWAT  VS+EVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQENALVSYSL
Sbjct: 435 LWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSL 494

Query: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVF 554
           VERR+GER+LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLGSNVTLQVF
Sbjct: 495 VERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVF 554

Query: 555 VLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLG 614
           VLDENDNAPALL PR     GAVSE+V  SVGAG VV KVRAVDADSGYNAWLSYELQ  
Sbjct: 555 VLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLSYELQPE 614

Query: 615 TGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674
           T SA IPFRVGLYTGEISTTRALDE D+PR RLLVLVKDHGEPALTATATVLVSLVESGQ
Sbjct: 615 TASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVSLVESGQ 674

Query: 675 APKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTEGARAP 734
           APK+SSRA VGA G E TLVDVNVYLIIAICAVSSLLVLT+LLYT LRCS  PTEG  AP
Sbjct: 675 APKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMPTEGECAP 734

Query: 735 GKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAEE--KQLSESE 792
           GKPTLVCSSAVGSWSYSQQRRQRVCSGE   KTDLMAFSP LS    S E   +  + S+
Sbjct: 735 GKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCAGSTERTGEPSASSD 794

Query: 793 YVGKVSLLLFLANSKIVLFKKFYMI 817
             GKV     L    I   +++Y +
Sbjct: 795 STGKVGFSSILFIYIIFFLERYYRL 819


>gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo
           sapiens]
          Length = 950

 Score = 1170 bits (3026), Expect = 0.0
 Identities = 605/784 (77%), Positives = 671/784 (85%), Gaps = 2/784 (0%)

Query: 15  LLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDL 74
           LLSLL+LA W VGSGQL YSVPEEA+HGTFVGRIAQDLGLEL ELVPRLF++ SK  GDL
Sbjct: 15  LLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGRGDL 74

Query: 75  LEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDNPPIFP 134
           LEVNLQNGILFVNSRIDREELCGRSAECSIH+EVIVDRPLQVFHV+VEVKDINDNPP+FP
Sbjct: 75  LEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPPVFP 134

Query: 135 MTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELSESLSL 194
            T K +   ESR LDSRFPLEGASDADIG NALL+Y+LS +E+FFLD+  +++  + L L
Sbjct: 135 ATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLGL 194

Query: 195 VLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLEN 254
           VL K LDREET E++LLL ATDGGKPELTGTVQ+LI VLD NDN P F +++Y VKL EN
Sbjct: 195 VLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPEN 254

Query: 255 TANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAK 314
            + GTLV+  NASD DEG N +I+YS  SDVS  I++KF +DP+SG I   G +D+EE++
Sbjct: 255 VSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEESR 314

Query: 315 SYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITV 374
           +++I V A DKG P ++GHC + +++VD+NDN P+++I +LS+P+ E+A LGTVIALI+V
Sbjct: 315 AHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIALISV 374

Query: 375 SDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434
            D D+  NG VTCSLTPHVPFKLVST+KNYYSLVLD ALDRESVSAYELVVTARDGGSPS
Sbjct: 375 IDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGGSPS 434

Query: 435 LWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494
           LWAT  VS+EVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQENALVSYSL
Sbjct: 435 LWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSL 494

Query: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVF 554
           VERR+GER+LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLGSNVTLQVF
Sbjct: 495 VERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVF 554

Query: 555 VLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLG 614
           VLDENDNAPALL PR     GAVSE+V  SVGAG VV KVRAVDADSGYNAWLSYELQ  
Sbjct: 555 VLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLSYELQPE 614

Query: 615 TGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674
           T SA IPFRVGLYTGEISTTRALDE D+PR RLLVLVKDHGEPALTATATVLVSLVESGQ
Sbjct: 615 TASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVSLVESGQ 674

Query: 675 APKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTEGARAP 734
           APK+SSRA VGA G E TLVDVNVYLIIAICAVSSLLVLT+LLYT LRCS  PTEG  AP
Sbjct: 675 APKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMPTEGECAP 734

Query: 735 GKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAEE--KQLSESE 792
           GKPTLVCSSAVGSWSYSQQRRQRVCSGE   KTDLMAFSP LS    S E   +  + S+
Sbjct: 735 GKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCAGSTERTGEPSASSD 794

Query: 793 YVGK 796
             GK
Sbjct: 795 STGK 798


>gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo
           sapiens]
          Length = 844

 Score = 1169 bits (3024), Expect = 0.0
 Identities = 612/796 (76%), Positives = 668/796 (83%), Gaps = 3/796 (0%)

Query: 10  GAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASK 69
           G    LLSLLLLAAWEVGSGQL YSV EEA+HGTFVGRIAQDLGLEL ELV RLFRVASK
Sbjct: 9   GVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASK 68

Query: 70  RHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDN 129
           RHGDLLEVNLQNGILFVNSRIDREELCGRS ECSIH+EVIVDRPLQVFHV+VEVKDINDN
Sbjct: 69  RHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDN 128

Query: 130 PPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELS 189
           PP F +T + +  PESRLLDSRFPLEGASDAD+G NALL+YKLS +E+F LDI    +  
Sbjct: 129 PPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKD 188

Query: 190 ESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKV 249
           +   LVL K LDREE  ++ LLL ATDGGKPE TG+V +LI VLD NDN P F + VY+V
Sbjct: 189 KFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEV 248

Query: 250 KLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLD 309
           K+ EN  N TLV++LNASD+DEG N E++YS  S V  TI+ KF I+  +GEI+    +D
Sbjct: 249 KMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAID 308

Query: 310 YEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVI 369
           +E++ +YEI V  TDKG P M GHC + ++L+D NDN+PEV +TSLSLP+ E+A +GTVI
Sbjct: 309 FEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVI 368

Query: 370 ALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429
           ALI+VSD DSG NG VTCSLTPHVPFKLVST+KNYYSLVLDSALDRE VSAYELVVTARD
Sbjct: 369 ALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARD 428

Query: 430 GGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENAL 489
           GGSP LWAT SVS+EVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSAWDADAQENAL
Sbjct: 429 GGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENAL 488

Query: 490 VSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNV 549
           VSYSLVERR+GER+LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARD GVPPLGSN+
Sbjct: 489 VSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNL 548

Query: 550 TLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSY 609
           TLQVFVLDENDNAPALLA  AG+A GAVSELV  SV AGHVVAKVRAVDADSGYNAWLSY
Sbjct: 549 TLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSY 608

Query: 610 ELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669
           ELQ     ARIPFRVGLYTGEISTTRALDE DSPR RLLVLVKDHGEP+LTATATVLVSL
Sbjct: 609 ELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSL 668

Query: 670 VESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTE 729
           VE  QAPKASSRA VG A  E  LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS  PTE
Sbjct: 669 VEGSQAPKASSRASVGVA-PEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPTE 727

Query: 730 GARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP--DSAEEKQ 787
           GA  P KPTLVCSSAVGSWSYSQQRRQRVCSGE  PK DLMAFSPSL   P  D   E Q
Sbjct: 728 GACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCPMVDVDGEDQ 787

Query: 788 LSESEYVGKVSLLLFL 803
               ++  KV   +F+
Sbjct: 788 SIGGDHSRKVGYYVFI 803


>gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo
           sapiens]
          Length = 948

 Score = 1167 bits (3018), Expect = 0.0
 Identities = 606/771 (78%), Positives = 658/771 (85%), Gaps = 1/771 (0%)

Query: 10  GAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASK 69
           G    LLSLLLLAAWEVGSGQL YSV EEA+HGTFVGRIAQDLGLEL ELV RLFRVASK
Sbjct: 9   GVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASK 68

Query: 70  RHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDN 129
           RHGDLLEVNLQNGILFVNSRIDREELCGRS ECSIH+EVIVDRPLQVFHV+VEVKDINDN
Sbjct: 69  RHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDN 128

Query: 130 PPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELS 189
           PP F +T + +  PESRLLDSRFPLEGASDAD+G NALL+YKLS +E+F LDI    +  
Sbjct: 129 PPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKD 188

Query: 190 ESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKV 249
           +   LVL K LDREE  ++ LLL ATDGGKPE TG+V +LI VLD NDN P F + VY+V
Sbjct: 189 KFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEV 248

Query: 250 KLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLD 309
           K+ EN  N TLV++LNASD+DEG N E++YS  S V  TI+ KF I+  +GEI+    +D
Sbjct: 249 KMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAID 308

Query: 310 YEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVI 369
           +E++ +YEI V  TDKG P M GHC + ++L+D NDN+PEV +TSLSLP+ E+A +GTVI
Sbjct: 309 FEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVI 368

Query: 370 ALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429
           ALI+VSD DSG NG VTCSLTPHVPFKLVST+KNYYSLVLDSALDRE VSAYELVVTARD
Sbjct: 369 ALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARD 428

Query: 430 GGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENAL 489
           GGSP LWAT SVS+EVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSAWDADAQENAL
Sbjct: 429 GGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENAL 488

Query: 490 VSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNV 549
           VSYSLVERR+GER+LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARD GVPPLGSN+
Sbjct: 489 VSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNL 548

Query: 550 TLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSY 609
           TLQVFVLDENDNAPALLA  AG+A GAVSELV  SV AGHVVAKVRAVDADSGYNAWLSY
Sbjct: 549 TLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSY 608

Query: 610 ELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669
           ELQ     ARIPFRVGLYTGEISTTRALDE DSPR RLLVLVKDHGEP+LTATATVLVSL
Sbjct: 609 ELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSL 668

Query: 670 VESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTE 729
           VE  QAPKASSRA VG A  E  LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS  PTE
Sbjct: 669 VEGSQAPKASSRASVGVA-PEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPTE 727

Query: 730 GARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP 780
           GA  P KPTLVCSSAVGSWSYSQQRRQRVCSGE  PK DLMAFSPSL   P
Sbjct: 728 GACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCP 778


>gi|14165402 protocadherin alpha 1 isoform 3 precursor [Homo
           sapiens]
          Length = 686

 Score =  817 bits (2110), Expect = 0.0
 Identities = 419/534 (78%), Positives = 460/534 (86%)

Query: 1   MASSIRRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELV 60
           M  S R G GA   LL LLLLAAWEVGSGQL YS+PEEAKHGTFVGR+AQDLGLEL ELV
Sbjct: 1   MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60

Query: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVE 120
           PRLFRVASK H DLLEVNLQNGILFVNSRIDREELC  SAECSIH+E+I DRPLQVFHVE
Sbjct: 61  PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120

Query: 121 VEVKDINDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFL 180
           V+VKDINDNPP+F    + I  PESRLL+SRFP+EGA+DADIG NALL+Y LS S++F L
Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180

Query: 181 DIQANDELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEP 240
           D++A+DELS+SL L L K LDREET E++LLL ATDGGKPEL GTV++LI VLDVNDN P
Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240

Query: 241 TFAQSVYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISG 300
            F Q+VY+V LLE TANGTLV  LNASDADEG N E+V+S  S +S  IQ KF +D  SG
Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300

Query: 301 EIRTKGKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPIS 360
           EIR   KLDYEE KSYEIQV A DKG+P MS HCK+ +K++D+NDN PE+++TSL LPI 
Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360

Query: 361 ENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420
           E+A L TVIALITVSDRDSG NG VTCSL PHVPFKLVSTFKNYYSLVLDSALDRES+S 
Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420

Query: 421 YELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480
           YELVVTARDGGSPSLWAT  VS+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA 
Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQ 534
           DADAQENALVSYSLVERRVGERALS+YVSVHAESGKVYALQPLDHEE+ELLQFQ
Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQ 534



 Score =  151 bits (381), Expect = 3e-36
 Identities = 124/429 (28%), Positives = 200/429 (46%), Gaps = 29/429 (6%)

Query: 194 LVLGKSLDREETAE------VNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVY 247
           L +   +DREE  +      ++L L+A    +P     V++  KV D+NDN P F     
Sbjct: 84  LFVNSRIDREELCQWSAECSIHLELIAD---RPLQVFHVEV--KVKDINDNPPVFRGREQ 138

Query: 248 KVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEI--RTK 305
            + + E+    +      A+DAD G N+ + Y+L      ++  + + D +S  +    +
Sbjct: 139 IIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSLDVEAS-DELSKSLWLELR 197

Query: 306 GKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASL 365
             LD EE     + +TATD G P + G  ++ + ++D+NDN P        + + E  + 
Sbjct: 198 KYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAPLFDQAVYRVHLLETTAN 257

Query: 366 GTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYS---LVLDSALDRESVSAYE 422
           GT++  +  SD D G NG V  S    +   +   FK   S   + L   LD E   +YE
Sbjct: 258 GTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSGEIRLIDKLDYEETKSYE 317

Query: 423 LVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDA 482
           + V A D GSP +     V ++V DVNDNAP  A     + ++E+ P    I  ++  D 
Sbjct: 318 IQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIREDAPLSTVIALITVSDR 377

Query: 483 DAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGV 542
           D+  N  V+ SL+   V  + +S++ + ++    +     LD E + + +  V+ARD G 
Sbjct: 378 DSGANGQVTCSLMPH-VPFKLVSTFKNYYS----LVLDSALDRESLSVYELVVTARDGGS 432

Query: 543 PPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSG 602
           P L +   + V V D NDNAPA   P         +  V  +   G  +  V A DAD+ 
Sbjct: 433 PSLWATARVSVEVADVNDNAPAFAQPE-------YTVFVKENNPPGCHIFTVSARDADAQ 485

Query: 603 YNAWLSYEL 611
            NA +SY L
Sbjct: 486 ENALVSYSL 494



 Score =  142 bits (357), Expect = 2e-33
 Identities = 113/346 (32%), Positives = 162/346 (46%), Gaps = 27/346 (7%)

Query: 336 ISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPF 395
           + +K+ DINDN P        + I E+  L +   +   +D D G N  +T +L+P   F
Sbjct: 119 VEVKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYF 178

Query: 396 KLVSTFKNYYS----LVLDSALDRESVSAYELVVTARDGGSPSLWATTSVSIEVADVNDN 451
            L     +  S    L L   LDRE      L++TA DGG P L  T  + I V DVNDN
Sbjct: 179 SLDVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDN 238

Query: 452 APAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL---VERRVGERALSSYV 508
           AP F Q  Y V + E    G  + T++A DAD   N  V +S    + R + E+      
Sbjct: 239 APLFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEK-----F 293

Query: 509 SVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAP 568
            V + SG++  +  LD+EE +  + QV A D G PP+ ++  + V VLD NDNAP L   
Sbjct: 294 KVDSSSGEIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVT 353

Query: 569 RAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLGTGSARIPFR-VGLY 627
              +    + E  P S     V+A +   D DSG N  ++  L        +PF+ V  +
Sbjct: 354 ---SLYLPIREDAPLST----VIALITVSDRDSGANGQVTCSLM-----PHVPFKLVSTF 401

Query: 628 TGEISTT--RALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVE 671
               S     ALD      + L+V  +D G P+L ATA V V + +
Sbjct: 402 KNYYSLVLDSALDRESLSVYELVVTARDGGSPSLWATARVSVEVAD 447


>gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo
           sapiens]
          Length = 685

 Score =  783 bits (2021), Expect = 0.0
 Identities = 397/525 (75%), Positives = 445/525 (84%)

Query: 10  GAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASK 69
           G    LLSLLLLAAWEVGSGQL YSV EEA+HGTFVGRIAQDLGLEL ELV RLFRVASK
Sbjct: 9   GVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASK 68

Query: 70  RHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDN 129
           RHGDLLEVNLQNGILFVNSRIDREELCGRS ECSIH+EVIVDRPLQVFHV+VEVKDINDN
Sbjct: 69  RHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDN 128

Query: 130 PPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELS 189
           PP F +T + +  PESRLLDSRFPLEGASDAD+G NALL+YKLS +E+F LDI    +  
Sbjct: 129 PPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKD 188

Query: 190 ESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKV 249
           +   LVL K LDREE  ++ LLL ATDGGKPE TG+V +LI VLD NDN P F + VY+V
Sbjct: 189 KFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEV 248

Query: 250 KLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLD 309
           K+ EN  N TLV++LNASD+DEG N E++YS  S V  TI+ KF I+  +GEI+    +D
Sbjct: 249 KMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAID 308

Query: 310 YEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVI 369
           +E++ +YEI V  TDKG P M GHC + ++L+D NDN+PEV +TSLSLP+ E+A +GTVI
Sbjct: 309 FEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVI 368

Query: 370 ALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429
           ALI+VSD DSG NG VTCSLTPHVPFKLVST+KNYYSLVLDSALDRE VSAYELVVTARD
Sbjct: 369 ALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARD 428

Query: 430 GGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENAL 489
           GGSP LWAT SVS+EVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSAWDADAQENAL
Sbjct: 429 GGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENAL 488

Query: 490 VSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQ 534
           VSYSLVERR+GER+LSSYVSVHAESGKVYALQPLDHEE+ELLQFQ
Sbjct: 489 VSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQ 533



 Score =  147 bits (372), Expect = 3e-35
 Identities = 122/425 (28%), Positives = 196/425 (46%), Gaps = 31/425 (7%)

Query: 230 IKVLDVNDNEPTFAQSVYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTI 289
           ++V D+NDN P F+ +  K+ + E+    +      ASDAD G N+ + Y L  +     
Sbjct: 120 VEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPN----- 174

Query: 290 QTKFTIDPISGEIRTKGK-------LDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVD 342
              F +D I+ + + K         LD EE    ++ +TATD G P  +G   + + ++D
Sbjct: 175 -EYFVLDIINKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLD 233

Query: 343 INDNTPEVSITSLSLPISENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTF- 401
            NDN P        + + EN    T++  +  SD D G N  +  S +  VP  +   F 
Sbjct: 234 ANDNAPIFDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFW 293

Query: 402 --KNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPE 459
             +    + ++ A+D E  + YE+ V   D G+P +    +V +E+ D NDN+P      
Sbjct: 294 INERTGEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTS 353

Query: 460 YTVFVKENNPPGCHIFTVSAWDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYA 519
            ++ VKE+   G  I  +S  D D+  N  V+ SL    V  + +S+Y + ++    +  
Sbjct: 354 LSLPVKEDAQVGTVIALISVSDHDSGANGQVTCSLTPH-VPFKLVSTYKNYYS----LVL 408

Query: 520 LQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSE 579
              LD E V   +  V+ARD G PPL +  ++ V V D NDNAPA        A    + 
Sbjct: 409 DSALDRERVSAYELVVTARDGGSPPLWATASVSVEVADVNDNAPAF-------AQSEYTV 461

Query: 580 LVPWSVGAGHVVAKVRAVDADSGYNAWLSYEL---QLGTGSARIPFRVGLYTGEISTTRA 636
            V  +   G  +  V A DAD+  NA +SY L   +LG  S      V   +G++   + 
Sbjct: 462 FVKENNPPGCHIFTVSAWDADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQP 521

Query: 637 LDEAD 641
           LD  +
Sbjct: 522 LDHEE 526



 Score =  139 bits (350), Expect = 1e-32
 Identities = 106/343 (30%), Positives = 161/343 (46%), Gaps = 21/343 (6%)

Query: 336 ISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPF 395
           + +++ DINDN P  S+T   L I E+  L +   L   SD D G N  +T  L+P+  F
Sbjct: 118 VDVEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYF 177

Query: 396 KLVSTFKN----YYSLVLDSALDRESVSAYELVVTARDGGSPSLWATTSVSIEVADVNDN 451
            L    K     +  LVL   LDRE     +L++TA DGG P    + S+ I V D NDN
Sbjct: 178 VLDIINKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDN 237

Query: 452 APAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSLVERRVGERALSSYVSVH 511
           AP F +P Y V + EN      +  ++A D+D   N  + YS     +    +     ++
Sbjct: 238 APIFDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSS--LVPPTIRRKFWIN 295

Query: 512 AESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRAG 571
             +G++     +D E+    +  V   D G PP+  + T+ V +LDENDN+P ++     
Sbjct: 296 ERTGEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVT--- 352

Query: 572 TAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLGTGSARIPFR-VGLYTGE 630
               ++S  V      G V+A +   D DSG N  ++  L     +  +PF+ V  Y   
Sbjct: 353 ----SLSLPVKEDAQVGTVIALISVSDHDSGANGQVTCSL-----TPHVPFKLVSTYKNY 403

Query: 631 ISTT--RALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVE 671
            S     ALD      + L+V  +D G P L ATA+V V + +
Sbjct: 404 YSLVLDSALDRERVSAYELVVTARDGGSPPLWATASVSVEVAD 446



 Score = 92.0 bits (227), Expect = 2e-18
 Identities = 82/271 (30%), Positives = 119/271 (43%), Gaps = 17/271 (6%)

Query: 441 VSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSLVERRVG 500
           V +EV D+NDN P F+  E  + + E+           A DAD  ENAL++Y L      
Sbjct: 118 VDVEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYF 177

Query: 501 ERALSSYVSVHAESGKVYALQPL-DHEEVELLQFQVSARDAGVPPLGSNVTLQVFVLDEN 559
              L        +   V  L+ L D EE   L+  ++A D G P    +V+L + VLD N
Sbjct: 178 --VLDIINKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDAN 235

Query: 560 DNAPALLAPRAGTAAGAVSELVPWSVGAGH-VVAKVRAVDADSGYNAWLSYELQ-LGTGS 617
           DNAP    P        V E+  +       +V ++ A D+D G N  + Y    L   +
Sbjct: 236 DNAPIFDRP--------VYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPT 287

Query: 618 ARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQAPK 677
            R  F +   TGEI    A+D  DS  + + V V D G P +    TVLV L++      
Sbjct: 288 IRRKFWINERTGEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDEND--- 344

Query: 678 ASSRAWVGAAGSEATLVDVNVYLIIAICAVS 708
            +S   +  + S     D  V  +IA+ +VS
Sbjct: 345 -NSPEVIVTSLSLPVKEDAQVGTVIALISVS 374


>gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo
           sapiens]
          Length = 686

 Score =  780 bits (2014), Expect = 0.0
 Identities = 391/520 (75%), Positives = 447/520 (85%)

Query: 15  LLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDL 74
           LL LLLLAAW+VGSGQL YSVPEEAKHGTFVGRIAQDLGLEL ELVPRLFR+ASK   DL
Sbjct: 15  LLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDREDL 74

Query: 75  LEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDNPPIFP 134
           LEVNLQNGILFVNSRIDREELCGRSAECSIH+EVIVDRPLQVFHV+VEV+DINDNPP+FP
Sbjct: 75  LEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPLFP 134

Query: 135 MTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELSESLSL 194
           +  + +   ESRL DS FPLEGASDAD+G N++L+YKLSSSE+F LD++ N + ++ + L
Sbjct: 135 VEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIGL 194

Query: 195 VLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLEN 254
           +L KSLDREE    NL L ATDGGKPELTGTVQ+L+ VLDVNDN PTF QS Y+V++ EN
Sbjct: 195 LLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFEN 254

Query: 255 TANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAK 314
             NGT V++LNASD DEG N  I YS  S V++ +   F+ID  +GEI  +G LD+E+  
Sbjct: 255 ADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQEN 314

Query: 315 SYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITV 374
            Y+I + ATDKG P M+GHC + ++++D NDN PE+++TSLSLP+ E+A  GTVIALI+V
Sbjct: 315 LYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALISV 374

Query: 375 SDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434
           +D DSG NG V CSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS
Sbjct: 375 NDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434

Query: 435 LWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494
           LWAT S+S+EVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQENALVSYSL
Sbjct: 435 LWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSL 494

Query: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQ 534
           VERRVGERALSSY+SVHAESGKVYALQPLDHEE+ELLQFQ
Sbjct: 495 VERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQ 534



 Score =  173 bits (439), Expect = 5e-43
 Identities = 138/472 (29%), Positives = 217/472 (45%), Gaps = 41/472 (8%)

Query: 199 SLDREETAEVNL----LLVATDGGKPELTG------------------TVQILIKVLDVN 236
           S DRE+  EVNL    L V +   + EL G                     + ++V D+N
Sbjct: 68  SKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDIN 127

Query: 237 DNEPTFAQSVYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTID 296
           DN P F     +V + E+    ++     ASDAD G NS + Y L S     +  K   D
Sbjct: 128 DNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSD 187

Query: 297 PISG-EIRTKGKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSL 355
                 +  K  LD EEA ++ + +TATD G P ++G  ++ + ++D+NDN P    +  
Sbjct: 188 DNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEY 247

Query: 356 SLPISENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTF---KNYYSLVLDSA 412
            + I ENA  GT +  +  SDRD G NG ++ S    V   ++  F   +N   +V+   
Sbjct: 248 EVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGN 307

Query: 413 LDRESVSAYELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGC 472
           LD E  + Y++++ A D G P +    +V + + D NDN P  A    ++ V+E+   G 
Sbjct: 308 LDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGT 367

Query: 473 HIFTVSAWDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQ 532
            I  +S  D D+  N  V+ SL    V  + +S++ + ++    +     LD E V   +
Sbjct: 368 VIALISVNDLDSGANGQVNCSLTPH-VPFKLVSTFKNYYS----LVLDSALDRESVSAYE 422

Query: 533 FQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVA 592
             V+ARD G P L +  +L V V D NDNAPA   P         +  V  +   G  + 
Sbjct: 423 LVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPE-------YTVFVKENNPPGCHIF 475

Query: 593 KVRAVDADSGYNAWLSYEL---QLGTGSARIPFRVGLYTGEISTTRALDEAD 641
            V A DAD+  NA +SY L   ++G  +      V   +G++   + LD  +
Sbjct: 476 TVSARDADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEE 527



 Score =  149 bits (376), Expect = 1e-35
 Identities = 107/343 (31%), Positives = 164/343 (47%), Gaps = 21/343 (6%)

Query: 336 ISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPF 395
           + +++ DINDN P   +    + I E+    +V  L   SD D G+N  +T  L+    F
Sbjct: 119 VDVEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYF 178

Query: 396 ----KLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWATTSVSIEVADVNDN 451
               K+ S       L+L  +LDRE   A+ L +TA DGG P L  T  + + V DVNDN
Sbjct: 179 GLDVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDN 238

Query: 452 APAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSLVERRVGERALSSYVSVH 511
           AP F Q EY V + EN   G  +  ++A D D   N  +SYS     +    +  + S+ 
Sbjct: 239 APTFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSF--NSLVAAMVIDHFSID 296

Query: 512 AESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRAG 571
             +G++     LD E+  L +  + A D G PP+  + T+ V +LD+NDN P +      
Sbjct: 297 RNTGEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEI------ 350

Query: 572 TAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLGTGSARIPFR-VGLYTGE 630
            A  ++S  V      G V+A +   D DSG N  ++  L     +  +PF+ V  +   
Sbjct: 351 -ALTSLSLPVREDAQFGTVIALISVNDLDSGANGQVNCSL-----TPHVPFKLVSTFKNY 404

Query: 631 ISTT--RALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVE 671
            S     ALD      + L+V  +D G P+L ATA++ V + +
Sbjct: 405 YSLVLDSALDRESVSAYELVVTARDGGSPSLWATASLSVEVAD 447



 Score = 39.7 bits (91), Expect = 0.012
 Identities = 50/196 (25%), Positives = 84/196 (42%), Gaps = 18/196 (9%)

Query: 484 AQENALVSYSLVER--RVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAG 541
           AQ+  L    LV R  R+  +     + V+ ++G ++    +D EE+     + S     
Sbjct: 49  AQDLGLELAELVPRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEV 108

Query: 542 VPPLGSNVT-LQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDAD 600
           +      V  + V V D NDN P  L P            +P SV          A DAD
Sbjct: 109 IVDRPLQVFHVDVEVRDINDNPP--LFPVEEQRVLIYESRLPDSV-----FPLEGASDAD 161

Query: 601 SGYNAWLSYELQLGTGSARIPFRVGLYTGE-----ISTTRALDEADSPRHRLLVLVKDHG 655
            G N+ L+Y+L   + S      V + + +     +   ++LD  ++P H L +   D G
Sbjct: 162 VGSNSILTYKL---SSSEYFGLDVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGG 218

Query: 656 EPALTATATVLVSLVE 671
           +P LT T  +LV++++
Sbjct: 219 KPELTGTVQLLVTVLD 234


>gi|14277677 protocadherin gamma subfamily C, 3 isoform 2 precursor
           [Homo sapiens]
          Length = 863

 Score =  595 bits (1534), Expect = e-170
 Identities = 306/698 (43%), Positives = 455/698 (65%), Gaps = 8/698 (1%)

Query: 18  LLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDLLEV 77
           LLLL A    S  + Y +PEE + G  VG +  +LGL+L  L  R FRV S       EV
Sbjct: 20  LLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFEV 79

Query: 78  NLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDNPPIFPMTV 137
           N + G +FVN R+DREELCG    C++ +E++V+ PL++F VEV ++DINDN P FP   
Sbjct: 80  NRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQE 139

Query: 138 KTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELSESLSLVLG 197
             +   E+    +RFPLE A D D+G N+L +Y+LS +E+F L +Q  ++ ++   LVL 
Sbjct: 140 MKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVLE 199

Query: 198 KSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLENTAN 257
           ++LDRE    + L+L A DGG P L+ ++ I IKVLD NDN P F QS+Y+ ++LE+  +
Sbjct: 200 RALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAPS 259

Query: 258 GTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAKSYE 317
           GT VV++ A+D DEGPN EI+YS GS   + ++  F +D ++G +  KG+LD+E+ K +E
Sbjct: 260 GTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLHE 319

Query: 318 IQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITVSDR 377
           I + A DKG      HCK+ +++VD+NDN PE+++TS+  P+ E+A LGTVIAL++V+D 
Sbjct: 320 IYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTDL 379

Query: 378 DSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWA 437
           D+G NG VTC + P +PF L S+ KNY++L   + LDRE+V  Y L +TARD G+PSL A
Sbjct: 380 DAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLSA 439

Query: 438 TTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSLVER 497
            T V ++V+D+NDN P  +Q  Y V+++ENN PG  I  +S WD DA +NA +S+ L+E+
Sbjct: 440 LTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLEQ 499

Query: 498 RVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVFVLD 557
                 +  Y +++ ++G V +L PLD+E+    +      D G P L +N+++ +FV D
Sbjct: 500 GAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVTD 559

Query: 558 ENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLGTGS 617
            NDNAP +L PR G   G+  E++P    AGH+V++V   DAD+G+NAWLSY L LG+ +
Sbjct: 560 RNDNAPQVLYPRPG---GSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSL-LGSPN 615

Query: 618 ARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQAPK 677
             + F +GL+TG+IST R + + DSPR  L VL+KD+GEP+L+ TAT+ VS+ E   +P+
Sbjct: 616 QSL-FAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTE--DSPE 672

Query: 678 ASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTV 715
           A +    G+A  E    ++  YL++++  VS   V+TV
Sbjct: 673 ARAEFPSGSAPREQK-KNLTFYLLLSLILVSVGFVVTV 709


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.131    0.370 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,905,826
Number of Sequences: 37866
Number of extensions: 1315951
Number of successful extensions: 9198
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 192
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 2248
Number of HSP's gapped (non-prelim): 750
length of query: 824
length of database: 18,247,518
effective HSP length: 111
effective length of query: 713
effective length of database: 14,044,392
effective search space: 10013651496
effective search space used: 10013651496
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.