Search of human proteins with 14165392

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo
sapiens]
         (792 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo sap...  1550   0.0  
gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo sapi...  1544   0.0  
gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo sap...  1203   0.0  
gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo sapi...  1203   0.0  
gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo sap...  1195   0.0  
gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo sapi...  1193   0.0  
gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo sapi...  1191   0.0  
gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens]  1191   0.0  
gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo sap...  1189   0.0  
gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo sapi...  1189   0.0  
gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo sapi...  1182   0.0  
gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens]  1182   0.0  
gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo sapi...  1180   0.0  
gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens]  1180   0.0  
gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo sapi...  1176   0.0  
gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens]  1176   0.0  
gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens]  1169   0.0  
gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo sapi...  1169   0.0  
gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens]  1169   0.0  
gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo sapi...  1167   0.0  
gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo sapi...  1161   0.0  
gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens]  1161   0.0  
gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens]  1157   0.0  
gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapi...  1156   0.0  
gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens]  1150   0.0  
gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo sapi...  1150   0.0  
gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo sap...   806   0.0  
gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo sapi...   771   0.0  
gi|14165402 protocadherin alpha 1 isoform 3 precursor [Homo sapi...   758   0.0  
gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precurs...   579   e-165

>gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo
           sapiens]
          Length = 792

 Score = 1550 bits (4013), Expect = 0.0
 Identities = 792/792 (100%), Positives = 792/792 (100%)

Query: 1   MVIIGPRGPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELV 60
           MVIIGPRGPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELV
Sbjct: 1   MVIIGPRGPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVD
Sbjct: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVD 120

Query: 121 VEVKDINDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFEL 180
           VEVKDINDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFEL
Sbjct: 121 VEVKDINDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFEL 180

Query: 181 KIKTKKDKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGP 240
           KIKTKKDKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGP
Sbjct: 181 KIKTKKDKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGP 240

Query: 241 AFDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTG 300
           AFDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTG
Sbjct: 241 AFDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTG 300

Query: 301 EIRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQ 360
           EIRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQ
Sbjct: 301 EIRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQ 360

Query: 361 EDAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420
           EDAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA
Sbjct: 361 EDAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480
           YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW
Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480

Query: 481 DADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA
Sbjct: 481 DADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALT 660

Query: 661 STATVLVSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTA 720
           STATVLVSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 661 STATVLVSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSAPPTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQLSR 780
           LRCSAPPTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQLSR
Sbjct: 721 LRCSAPPTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQLSR 780

Query: 781 EDCLNPPSEVSY 792
           EDCLNPPSEVSY
Sbjct: 781 EDCLNPPSEVSY 792


>gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo
           sapiens]
          Length = 941

 Score = 1544 bits (3998), Expect = 0.0
 Identities = 789/789 (100%), Positives = 789/789 (100%)

Query: 1   MVIIGPRGPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELV 60
           MVIIGPRGPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELV
Sbjct: 1   MVIIGPRGPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVD
Sbjct: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVD 120

Query: 121 VEVKDINDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFEL 180
           VEVKDINDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFEL
Sbjct: 121 VEVKDINDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFEL 180

Query: 181 KIKTKKDKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGP 240
           KIKTKKDKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGP
Sbjct: 181 KIKTKKDKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGP 240

Query: 241 AFDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTG 300
           AFDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTG
Sbjct: 241 AFDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTG 300

Query: 301 EIRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQ 360
           EIRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQ
Sbjct: 301 EIRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQ 360

Query: 361 EDAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420
           EDAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA
Sbjct: 361 EDAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480
           YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW
Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480

Query: 481 DADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA
Sbjct: 481 DADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALT 660

Query: 661 STATVLVSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTA 720
           STATVLVSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 661 STATVLVSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSAPPTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQLSR 780
           LRCSAPPTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQLSR
Sbjct: 721 LRCSAPPTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQLSR 780

Query: 781 EDCLNPPSE 789
           EDCLNPPSE
Sbjct: 781 EDCLNPPSE 789


>gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo
           sapiens]
          Length = 844

 Score = 1203 bits (3113), Expect = 0.0
 Identities = 626/767 (81%), Positives = 663/767 (86%), Gaps = 1/767 (0%)

Query: 10  GSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69
           G Q LLLSLLLLAAWEVGSGQLHYSVYEEA+HGTFVGRIAQDLGLELAELV RLFRVASK
Sbjct: 9   GVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASK 68

Query: 70  RHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDN 129
           RHGDLLEVNLQNGILFVNSRIDRE+LCGRS ECSIHLEVIVDRPLQVFHVDVEVKDINDN
Sbjct: 69  RHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDN 128

Query: 130 PPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDKS 189
           PP F   EQK+ + ES  LDS FPLEGASDAD+G N+LLTY LS NE F L I  KKDK 
Sbjct: 129 PPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKD 188

Query: 190 ILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYKV 249
             P LVLRKLLDRE+ P+L LLL   DGGKPE TGSV + I VLD NDN P FD+P Y+V
Sbjct: 189 KFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEV 248

Query: 250 VLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGELD 309
            + EN  N T VI+LNASD DEG+N E+ Y    ++P + +  F IN  TGEI++   +D
Sbjct: 249 KMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAID 308

Query: 310 FEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTVI 369
           FE++N YEI V+  DKG P M GH  VLVE+LD NDN PEV+VTSLSLPV+EDAQVGTVI
Sbjct: 309 FEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVI 368

Query: 370 ALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARD 429
           ALISVSD DSGANGQV CSLTPHVPFKLVSTYKNYYSLVLDSALDRE VSAYELVVTARD
Sbjct: 369 ALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARD 428

Query: 430 GGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNAL 489
           GGSP LWATA VSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSAWDADAQ+NAL
Sbjct: 429 GGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENAL 488

Query: 490 VSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549
           VSYSLVERR+GE +LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD GVPPLGSN+
Sbjct: 489 VSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNL 548

Query: 550 TLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609
           TLQVFVLDENDNAPALLA+PAGSAGGAVSELV RSV AGHVVAKVRAVDADSGYNAWLSY
Sbjct: 549 TLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSY 608

Query: 610 ELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLVSL 669
           ELQ AAVGA IPF VGLYTGEISTTR LDE D+PR RLLVLVKDHGEP+LT+TATVLVSL
Sbjct: 609 ELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSL 668

Query: 670 VENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPPTV 729
           VE  QAPK SSRASVG V PE ALVD+NVYLIIAICAVSSLLVLTLLLYTALRCSA PT 
Sbjct: 669 VEGSQAPKASSRASVG-VAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPTE 727

Query: 730 SRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776
             C P KPTLVCSSAVGSWSYSQQRRQRVCS E  PK DLMAFSPSL
Sbjct: 728 GACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSL 774


>gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo
           sapiens]
          Length = 948

 Score = 1203 bits (3113), Expect = 0.0
 Identities = 626/767 (81%), Positives = 663/767 (86%), Gaps = 1/767 (0%)

Query: 10  GSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69
           G Q LLLSLLLLAAWEVGSGQLHYSVYEEA+HGTFVGRIAQDLGLELAELV RLFRVASK
Sbjct: 9   GVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASK 68

Query: 70  RHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDN 129
           RHGDLLEVNLQNGILFVNSRIDRE+LCGRS ECSIHLEVIVDRPLQVFHVDVEVKDINDN
Sbjct: 69  RHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDN 128

Query: 130 PPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDKS 189
           PP F   EQK+ + ES  LDS FPLEGASDAD+G N+LLTY LS NE F L I  KKDK 
Sbjct: 129 PPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKD 188

Query: 190 ILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYKV 249
             P LVLRKLLDRE+ P+L LLL   DGGKPE TGSV + I VLD NDN P FD+P Y+V
Sbjct: 189 KFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEV 248

Query: 250 VLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGELD 309
            + EN  N T VI+LNASD DEG+N E+ Y    ++P + +  F IN  TGEI++   +D
Sbjct: 249 KMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAID 308

Query: 310 FEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTVI 369
           FE++N YEI V+  DKG P M GH  VLVE+LD NDN PEV+VTSLSLPV+EDAQVGTVI
Sbjct: 309 FEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVI 368

Query: 370 ALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARD 429
           ALISVSD DSGANGQV CSLTPHVPFKLVSTYKNYYSLVLDSALDRE VSAYELVVTARD
Sbjct: 369 ALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARD 428

Query: 430 GGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNAL 489
           GGSP LWATA VSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSAWDADAQ+NAL
Sbjct: 429 GGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENAL 488

Query: 490 VSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549
           VSYSLVERR+GE +LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD GVPPLGSN+
Sbjct: 489 VSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNL 548

Query: 550 TLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609
           TLQVFVLDENDNAPALLA+PAGSAGGAVSELV RSV AGHVVAKVRAVDADSGYNAWLSY
Sbjct: 549 TLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSY 608

Query: 610 ELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLVSL 669
           ELQ AAVGA IPF VGLYTGEISTTR LDE D+PR RLLVLVKDHGEP+LT+TATVLVSL
Sbjct: 609 ELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSL 668

Query: 670 VENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPPTV 729
           VE  QAPK SSRASVG V PE ALVD+NVYLIIAICAVSSLLVLTLLLYTALRCSA PT 
Sbjct: 669 VEGSQAPKASSRASVG-VAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPTE 727

Query: 730 SRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776
             C P KPTLVCSSAVGSWSYSQQRRQRVCS E  PK DLMAFSPSL
Sbjct: 728 GACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSL 774


>gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo
           sapiens]
          Length = 810

 Score = 1195 bits (3091), Expect = 0.0
 Identities = 623/795 (78%), Positives = 677/795 (85%), Gaps = 10/795 (1%)

Query: 7   RGPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRV 66
           RG G+ RL L LLLL  WEVGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV RLFRV
Sbjct: 7   RGLGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRV 66

Query: 67  ASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDI 126
           ASK HGDLLEVNLQNGILFVNSRIDRE+LCG+SAECSIHLEVIVDRPLQVFHV+VEVKDI
Sbjct: 67  ASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDI 126

Query: 127 NDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKK 186
           NDNPPVF  REQK+ ++ES   DS FPLEGASDADI  N+LLTY LS NE F L   T  
Sbjct: 127 NDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNG 186

Query: 187 DKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPS 246
            +     L+L+K LDRE+TP+LNLLL   DGGKPELTG+V++ + VLDVNDN P FDK  
Sbjct: 187 KQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSE 246

Query: 247 YKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYG 306
           YKV L EN   +T V++LNA+D DEG+NGE++Y +  I P + + +F+++ + GE+R+ G
Sbjct: 247 YKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMSIKP-NGRHLFTLDQNNGEVRVNG 305

Query: 307 ELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVG 366
            LD+EEN  Y+I+V A DKG P MAGH  V VE+LD NDN PEV VTSLSLPV+EDAQ  
Sbjct: 306 TLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPS 365

Query: 367 TVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVT 426
           TVIALISVSDRDSG NGQV CSLTPHVPFKLVST+KNYYSLVLDSALDRE+V AYELVVT
Sbjct: 366 TVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVT 425

Query: 427 ARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQK 486
           ARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+
Sbjct: 426 ARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQE 485

Query: 487 NALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLG 546
           NALVSYSLVERR+G+ ALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL 
Sbjct: 486 NALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLS 545

Query: 547 SNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAW 606
           SNVTLQVFVLDENDNAPALLAT AGSAGGAV++LVPRSVGAGHVVAKVRAVDADSGYNAW
Sbjct: 546 SNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNAW 605

Query: 607 LSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVL 666
           LSYELQPAA G+ IPF VGLYTGEISTTR LDEAD+PRHRLLVLVKDHGEPALT+TATVL
Sbjct: 606 LSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVL 665

Query: 667 VSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAP 726
           VSLVE+GQAPK SSR   GA  PEAALVD+NVYLIIAIC VSSLLVLTLLLYTAL  SA 
Sbjct: 666 VSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSAT 725

Query: 727 PTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQLS------- 779
           PT   CAPGKPTLVCS AVGSWSYSQQRRQRVCS E PPKTDLMAFSPSL L        
Sbjct: 726 PTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNKEEEG 785

Query: 780 --REDCLNPPSEVSY 792
             +E   N P +VS+
Sbjct: 786 ERQEPGSNHPGQVSF 800


>gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo
           sapiens]
          Length = 949

 Score = 1193 bits (3087), Expect = 0.0
 Identities = 618/772 (80%), Positives = 669/772 (86%), Gaps = 1/772 (0%)

Query: 7   RGPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRV 66
           RG G+ RL L LLLL  WEVGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV RLFRV
Sbjct: 7   RGLGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRV 66

Query: 67  ASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDI 126
           ASK HGDLLEVNLQNGILFVNSRIDRE+LCG+SAECSIHLEVIVDRPLQVFHV+VEVKDI
Sbjct: 67  ASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDI 126

Query: 127 NDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKK 186
           NDNPPVF  REQK+ ++ES   DS FPLEGASDADI  N+LLTY LS NE F L   T  
Sbjct: 127 NDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNG 186

Query: 187 DKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPS 246
            +     L+L+K LDRE+TP+LNLLL   DGGKPELTG+V++ + VLDVNDN P FDK  
Sbjct: 187 KQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSE 246

Query: 247 YKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYG 306
           YKV L EN   +T V++LNA+D DEG+NGE++Y +  I P + + +F+++ + GE+R+ G
Sbjct: 247 YKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMSIKP-NGRHLFTLDQNNGEVRVNG 305

Query: 307 ELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVG 366
            LD+EEN  Y+I+V A DKG P MAGH  V VE+LD NDN PEV VTSLSLPV+EDAQ  
Sbjct: 306 TLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPS 365

Query: 367 TVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVT 426
           TVIALISVSDRDSG NGQV CSLTPHVPFKLVST+KNYYSLVLDSALDRE+V AYELVVT
Sbjct: 366 TVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVT 425

Query: 427 ARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQK 486
           ARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+
Sbjct: 426 ARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQE 485

Query: 487 NALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLG 546
           NALVSYSLVERR+G+ ALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL 
Sbjct: 486 NALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLS 545

Query: 547 SNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAW 606
           SNVTLQVFVLDENDNAPALLAT AGSAGGAV++LVPRSVGAGHVVAKVRAVDADSGYNAW
Sbjct: 546 SNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNAW 605

Query: 607 LSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVL 666
           LSYELQPAA G+ IPF VGLYTGEISTTR LDEAD+PRHRLLVLVKDHGEPALT+TATVL
Sbjct: 606 LSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVL 665

Query: 667 VSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAP 726
           VSLVE+GQAPK SSR   GA  PEAALVD+NVYLIIAIC VSSLLVLTLLLYTAL  SA 
Sbjct: 666 VSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSAT 725

Query: 727 PTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQL 778
           PT   CAPGKPTLVCS AVGSWSYSQQRRQRVCS E PPKTDLMAFSPSL L
Sbjct: 726 PTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPL 777


>gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo
           sapiens]
          Length = 814

 Score = 1191 bits (3081), Expect = 0.0
 Identities = 613/767 (79%), Positives = 663/767 (86%)

Query: 10  GSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69
           GS RLLL LLLLAAW+VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFRVASK
Sbjct: 10  GSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69

Query: 70  RHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDN 129
           RH DLLEV+LQNGILFVNSRIDRE+LCGRSAECSIHLEVIVDRPLQVFHVDVEVKD+NDN
Sbjct: 70  RHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDN 129

Query: 130 PPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDKS 189
           PPVFR ++QK+ VSES   DS FPLEGASDAD+G NS+LTY LS ++ F L + +K D++
Sbjct: 130 PPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDEN 189

Query: 190 ILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYKV 249
            L ELVLRK LDRE  P  +L L   DGGKPELTG+VQ+ +TVLDVNDN P F++  Y+V
Sbjct: 190 KLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249

Query: 250 VLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGELD 309
            + EN  N T VI+LNASDPDEG NG ISY    ++       FSI+ +TGEI I G LD
Sbjct: 250 RIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLD 309

Query: 310 FEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTVI 369
           FE+ N Y+I ++A DKG P MAGH  VLV +LD NDNVPE+ +TSLSLPV+EDAQ GTVI
Sbjct: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369

Query: 370 ALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARD 429
           ALISV+D DSGANGQV CSL PHVPFKLVST+KNYYSLVLDSALDRE VSAYELVVTARD
Sbjct: 370 ALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARD 429

Query: 430 GGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNAL 489
           GGSPSLWATA +SVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL
Sbjct: 430 GGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489

Query: 490 VSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549
           VSYSLVERRVGE +LSSY+SVH ESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV
Sbjct: 490 VSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549

Query: 550 TLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609
           TLQVFVLDENDNAPALL    G  GGA S+LVPRSVGAGHVVAKVRAVDADSGYNAWLSY
Sbjct: 550 TLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609

Query: 610 ELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLVSL 669
           ELQPAA    IPF VGLYTGEISTTR+LDEAD+PRHRLLVLVKDHGEPALT+TATVLVSL
Sbjct: 610 ELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669

Query: 670 VENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPPTV 729
           VE+GQAPK SSR S G + PEAALVD+NVYLIIAICAVSSLLVLTLLLYTALRCSA PT 
Sbjct: 670 VESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTE 729

Query: 730 SRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776
             C  GKPTLVCSSAVGSWSYSQQ+ QRVCS E PPKTDLMAFSP L
Sbjct: 730 GGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCL 776


>gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score = 1191 bits (3081), Expect = 0.0
 Identities = 613/767 (79%), Positives = 663/767 (86%)

Query: 10  GSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69
           GS RLLL LLLLAAW+VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFRVASK
Sbjct: 10  GSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69

Query: 70  RHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDN 129
           RH DLLEV+LQNGILFVNSRIDRE+LCGRSAECSIHLEVIVDRPLQVFHVDVEVKD+NDN
Sbjct: 70  RHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDN 129

Query: 130 PPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDKS 189
           PPVFR ++QK+ VSES   DS FPLEGASDAD+G NS+LTY LS ++ F L + +K D++
Sbjct: 130 PPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDEN 189

Query: 190 ILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYKV 249
            L ELVLRK LDRE  P  +L L   DGGKPELTG+VQ+ +TVLDVNDN P F++  Y+V
Sbjct: 190 KLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249

Query: 250 VLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGELD 309
            + EN  N T VI+LNASDPDEG NG ISY    ++       FSI+ +TGEI I G LD
Sbjct: 250 RIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLD 309

Query: 310 FEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTVI 369
           FE+ N Y+I ++A DKG P MAGH  VLV +LD NDNVPE+ +TSLSLPV+EDAQ GTVI
Sbjct: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369

Query: 370 ALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARD 429
           ALISV+D DSGANGQV CSL PHVPFKLVST+KNYYSLVLDSALDRE VSAYELVVTARD
Sbjct: 370 ALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARD 429

Query: 430 GGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNAL 489
           GGSPSLWATA +SVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL
Sbjct: 430 GGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489

Query: 490 VSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549
           VSYSLVERRVGE +LSSY+SVH ESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV
Sbjct: 490 VSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549

Query: 550 TLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609
           TLQVFVLDENDNAPALL    G  GGA S+LVPRSVGAGHVVAKVRAVDADSGYNAWLSY
Sbjct: 550 TLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609

Query: 610 ELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLVSL 669
           ELQPAA    IPF VGLYTGEISTTR+LDEAD+PRHRLLVLVKDHGEPALT+TATVLVSL
Sbjct: 610 ELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669

Query: 670 VENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPPTV 729
           VE+GQAPK SSR S G + PEAALVD+NVYLIIAICAVSSLLVLTLLLYTALRCSA PT 
Sbjct: 670 VESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTE 729

Query: 730 SRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776
             C  GKPTLVCSSAVGSWSYSQQ+ QRVCS E PPKTDLMAFSP L
Sbjct: 730 GGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCL 776


>gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo
           sapiens]
          Length = 807

 Score = 1189 bits (3076), Expect = 0.0
 Identities = 611/769 (79%), Positives = 666/769 (86%)

Query: 8   GPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67
           GP  ++LLL LL+LAAWE GSGQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFRVA
Sbjct: 8   GPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67

Query: 68  SKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIN 127
           SKRHGDLLEVNLQNGILFVNSRIDRE+LCGRSAECSIHLEVIVDRPLQVFHV+V+V+DIN
Sbjct: 68  SKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDIN 127

Query: 128 DNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKD 187
           DNPP+F E ++++ ++ES P ++ FPL+GASDADIGVNS LTY L  N+ F L  +   +
Sbjct: 128 DNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLE 187

Query: 188 KSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSY 247
           +     LVLRK LDRE+  + +LLL   DGGKPELTG+VQ+ IT+LDVNDN P F +  Y
Sbjct: 188 QMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVY 247

Query: 248 KVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGE 307
           KV + EN  N T VI+LNA+DPD+G NG+I Y  +  +  +    F+INP+ GEIR  G+
Sbjct: 248 KVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGK 307

Query: 308 LDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGT 367
           LDFEE   YEI V A+DKG   MAGH  +LVEVLDVNDN PEV +TSLSLP++ED Q   
Sbjct: 308 LDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPSA 367

Query: 368 VIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTA 427
           +IALISVSDRDSG+NGQV C+LTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTA
Sbjct: 368 IIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTA 427

Query: 428 RDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKN 487
           RDGGSPSLWATA VSV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+N
Sbjct: 428 RDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQEN 487

Query: 488 ALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS 547
           ALVSYSLVERRVGE ALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD+GVPPLGS
Sbjct: 488 ALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLGS 547

Query: 548 NVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWL 607
           NVTLQVFVLDENDNAPALL   AGSAGG VSEL+PRSVGAGHVVAKVRAVDADSGYNAWL
Sbjct: 548 NVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWL 607

Query: 608 SYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLV 667
           SYELQ AAVGA IPF VGLYTGEISTTR LDE DAP HRLLVLVKDHGEPALT+TATVL+
Sbjct: 608 SYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVLL 667

Query: 668 SLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPP 727
           SLVE+GQAP+ SSRAS GAV PEAALVD+NVYLIIAICAVSSLLVLTLLLYTALRCSAPP
Sbjct: 668 SLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPP 727

Query: 728 TVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776
           T   CAPGKPTLVCSSA GSWSYSQQRR RVCS E P KTDLMAFSPSL
Sbjct: 728 TEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSL 776


>gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo
           sapiens]
          Length = 950

 Score = 1189 bits (3076), Expect = 0.0
 Identities = 611/769 (79%), Positives = 666/769 (86%)

Query: 8   GPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67
           GP  ++LLL LL+LAAWE GSGQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFRVA
Sbjct: 8   GPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67

Query: 68  SKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIN 127
           SKRHGDLLEVNLQNGILFVNSRIDRE+LCGRSAECSIHLEVIVDRPLQVFHV+V+V+DIN
Sbjct: 68  SKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDIN 127

Query: 128 DNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKD 187
           DNPP+F E ++++ ++ES P ++ FPL+GASDADIGVNS LTY L  N+ F L  +   +
Sbjct: 128 DNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLE 187

Query: 188 KSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSY 247
           +     LVLRK LDRE+  + +LLL   DGGKPELTG+VQ+ IT+LDVNDN P F +  Y
Sbjct: 188 QMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVY 247

Query: 248 KVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGE 307
           KV + EN  N T VI+LNA+DPD+G NG+I Y  +  +  +    F+INP+ GEIR  G+
Sbjct: 248 KVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGK 307

Query: 308 LDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGT 367
           LDFEE   YEI V A+DKG   MAGH  +LVEVLDVNDN PEV +TSLSLP++ED Q   
Sbjct: 308 LDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPSA 367

Query: 368 VIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTA 427
           +IALISVSDRDSG+NGQV C+LTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTA
Sbjct: 368 IIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTA 427

Query: 428 RDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKN 487
           RDGGSPSLWATA VSV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+N
Sbjct: 428 RDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQEN 487

Query: 488 ALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS 547
           ALVSYSLVERRVGE ALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD+GVPPLGS
Sbjct: 488 ALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLGS 547

Query: 548 NVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWL 607
           NVTLQVFVLDENDNAPALL   AGSAGG VSEL+PRSVGAGHVVAKVRAVDADSGYNAWL
Sbjct: 548 NVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWL 607

Query: 608 SYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLV 667
           SYELQ AAVGA IPF VGLYTGEISTTR LDE DAP HRLLVLVKDHGEPALT+TATVL+
Sbjct: 608 SYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVLL 667

Query: 668 SLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPP 727
           SLVE+GQAP+ SSRAS GAV PEAALVD+NVYLIIAICAVSSLLVLTLLLYTALRCSAPP
Sbjct: 668 SLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPP 727

Query: 728 TVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776
           T   CAPGKPTLVCSSA GSWSYSQQRR RVCS E P KTDLMAFSPSL
Sbjct: 728 TEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSL 776


>gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo
           sapiens]
          Length = 803

 Score = 1182 bits (3057), Expect = 0.0
 Identities = 612/767 (79%), Positives = 659/767 (85%)

Query: 10  GSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69
           G Q LLL LLLLAAW+VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFR+ASK
Sbjct: 10  GKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASK 69

Query: 70  RHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDN 129
              DLLEVNLQNGILFVNSRIDRE+LCGRSAECSIHLEVIVDRPLQVFHVDVEV+DINDN
Sbjct: 70  DREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDN 129

Query: 130 PPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDKS 189
           PP+F   EQ+V + ES   DS FPLEGASDAD+G NS+LTY LS +E F L +K   D +
Sbjct: 130 PPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDN 189

Query: 190 ILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYKV 249
               L+L+K LDRE+ P  NL L   DGGKPELTG+VQ+ +TVLDVNDN P F++  Y+V
Sbjct: 190 KQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249

Query: 250 VLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGELD 309
            + EN  N T VI+LNASD DEG NG ISY    ++       FSI+ +TGEI I G LD
Sbjct: 250 RIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLD 309

Query: 310 FEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTVI 369
           FE+ N Y+I ++A DKG P MAGH  VLV +LD NDNVPE+ +TSLSLPV+EDAQ GTVI
Sbjct: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369

Query: 370 ALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARD 429
           ALISV+D DSGANGQV CSLTPHVPFKLVST+KNYYSLVLDSALDRESVSAYELVVTARD
Sbjct: 370 ALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429

Query: 430 GGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNAL 489
           GGSPSLWATA +SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL
Sbjct: 430 GGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489

Query: 490 VSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549
           VSYSLVERRVGE ALSSY+SVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV
Sbjct: 490 VSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549

Query: 550 TLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609
           TLQVFVLDENDNAPALLA   G  GGAVSELVPRS+GAG VVAKVRAVDADSGYNAWLSY
Sbjct: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSY 609

Query: 610 ELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLVSL 669
           ELQP A  A  PF VGLYTGEISTTR+LDEAD+PRHRLLVLVKDHGEPALT+TATVLVSL
Sbjct: 610 ELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669

Query: 670 VENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPPTV 729
           VE+GQAPK SSRASVGA  PEAALVD+NVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 
Sbjct: 670 VESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTE 729

Query: 730 SRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776
             C   KPTLVCSSAVGSWSYSQQRRQRVCS E PPK DLMAFSPSL
Sbjct: 730 GACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSL 776


>gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score = 1182 bits (3057), Expect = 0.0
 Identities = 612/767 (79%), Positives = 659/767 (85%)

Query: 10  GSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69
           G Q LLL LLLLAAW+VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFR+ASK
Sbjct: 10  GKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASK 69

Query: 70  RHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDN 129
              DLLEVNLQNGILFVNSRIDRE+LCGRSAECSIHLEVIVDRPLQVFHVDVEV+DINDN
Sbjct: 70  DREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDN 129

Query: 130 PPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDKS 189
           PP+F   EQ+V + ES   DS FPLEGASDAD+G NS+LTY LS +E F L +K   D +
Sbjct: 130 PPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDN 189

Query: 190 ILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYKV 249
               L+L+K LDRE+ P  NL L   DGGKPELTG+VQ+ +TVLDVNDN P F++  Y+V
Sbjct: 190 KQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249

Query: 250 VLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGELD 309
            + EN  N T VI+LNASD DEG NG ISY    ++       FSI+ +TGEI I G LD
Sbjct: 250 RIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLD 309

Query: 310 FEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTVI 369
           FE+ N Y+I ++A DKG P MAGH  VLV +LD NDNVPE+ +TSLSLPV+EDAQ GTVI
Sbjct: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369

Query: 370 ALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARD 429
           ALISV+D DSGANGQV CSLTPHVPFKLVST+KNYYSLVLDSALDRESVSAYELVVTARD
Sbjct: 370 ALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429

Query: 430 GGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNAL 489
           GGSPSLWATA +SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL
Sbjct: 430 GGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489

Query: 490 VSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549
           VSYSLVERRVGE ALSSY+SVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV
Sbjct: 490 VSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549

Query: 550 TLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609
           TLQVFVLDENDNAPALLA   G  GGAVSELVPRS+GAG VVAKVRAVDADSGYNAWLSY
Sbjct: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSY 609

Query: 610 ELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLVSL 669
           ELQP A  A  PF VGLYTGEISTTR+LDEAD+PRHRLLVLVKDHGEPALT+TATVLVSL
Sbjct: 610 ELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669

Query: 670 VENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPPTV 729
           VE+GQAPK SSRASVGA  PEAALVD+NVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 
Sbjct: 670 VESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTE 729

Query: 730 SRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776
             C   KPTLVCSSAVGSWSYSQQRRQRVCS E PPK DLMAFSPSL
Sbjct: 730 GACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSL 776


>gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo
           sapiens]
          Length = 798

 Score = 1180 bits (3053), Expect = 0.0
 Identities = 617/775 (79%), Positives = 665/775 (85%), Gaps = 2/775 (0%)

Query: 8   GPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67
           G  S+RLLL LLLLAAWE G+GQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFRVA
Sbjct: 8   GQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67

Query: 68  SKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIN 127
           SK  G LLEVNLQNGILFVNSRIDRE+LC RSAECSIHLEVIVDRPLQVFHVDVEV+DIN
Sbjct: 68  SKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDIN 127

Query: 128 DNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKD 187
           DNPPVF   ++ + ++ES PLDS FPLEGASDADIG N+LLTY LS NE F L+ K   D
Sbjct: 128 DNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLE-KPPDD 186

Query: 188 KSILP-ELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPS 246
           + +    L+LRK LDRE+ P++ L+L   DGGKPELTG+VQ+ ITVLD NDN PAFD+  
Sbjct: 187 ELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTI 246

Query: 247 YKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYG 306
           YKV L ENV N T VI+LNASD DEGLNG+I Y     +  + K  F I+P TG+I + G
Sbjct: 247 YKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKG 306

Query: 307 ELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVG 366
            +DFEE+ +YEI V  IDKG   ++GH  V+VEV D NDNVP++   SLSLP++EDA +G
Sbjct: 307 YIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLG 366

Query: 367 TVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVT 426
           TVIALISVSD+D G NG V CSLT HVPFKLVST+KNYYSLVLDSALDRESVSAYELVVT
Sbjct: 367 TVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVT 426

Query: 427 ARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQK 486
           ARDGGSPSLWATA VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQ+
Sbjct: 427 ARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQE 486

Query: 487 NALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLG 546
           NALVSYSLVERRVGE ALSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARDAGVPPLG
Sbjct: 487 NALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLG 546

Query: 547 SNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAW 606
           SNVTLQVFVLDENDNAPALLA  AG  GGAVSELVP SVG GHVVAKVRAVDADSGYNAW
Sbjct: 547 SNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAW 606

Query: 607 LSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVL 666
           LSYELQP   GA IPF VGLYTGEISTTR LDE DAPRHRLLVLVKDHGEPALT+TATVL
Sbjct: 607 LSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVL 666

Query: 667 VSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAP 726
           VSLVE+GQAPK SSRA VGAV P+AALVD+NVYLIIAICAVSSLLVLTLLLYTALRCSA 
Sbjct: 667 VSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAL 726

Query: 727 PTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQLSRE 781
           PT   CAPGKPTLVCSSAVGSWSYSQQRR RVCS E PPKTDLMAFSPSL  SR+
Sbjct: 727 PTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSRD 781


>gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens]
          Length = 947

 Score = 1180 bits (3053), Expect = 0.0
 Identities = 617/775 (79%), Positives = 665/775 (85%), Gaps = 2/775 (0%)

Query: 8   GPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67
           G  S+RLLL LLLLAAWE G+GQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFRVA
Sbjct: 8   GQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67

Query: 68  SKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIN 127
           SK  G LLEVNLQNGILFVNSRIDRE+LC RSAECSIHLEVIVDRPLQVFHVDVEV+DIN
Sbjct: 68  SKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDIN 127

Query: 128 DNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKD 187
           DNPPVF   ++ + ++ES PLDS FPLEGASDADIG N+LLTY LS NE F L+ K   D
Sbjct: 128 DNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLE-KPPDD 186

Query: 188 KSILP-ELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPS 246
           + +    L+LRK LDRE+ P++ L+L   DGGKPELTG+VQ+ ITVLD NDN PAFD+  
Sbjct: 187 ELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTI 246

Query: 247 YKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYG 306
           YKV L ENV N T VI+LNASD DEGLNG+I Y     +  + K  F I+P TG+I + G
Sbjct: 247 YKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKG 306

Query: 307 ELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVG 366
            +DFEE+ +YEI V  IDKG   ++GH  V+VEV D NDNVP++   SLSLP++EDA +G
Sbjct: 307 YIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLG 366

Query: 367 TVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVT 426
           TVIALISVSD+D G NG V CSLT HVPFKLVST+KNYYSLVLDSALDRESVSAYELVVT
Sbjct: 367 TVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVT 426

Query: 427 ARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQK 486
           ARDGGSPSLWATA VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQ+
Sbjct: 427 ARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQE 486

Query: 487 NALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLG 546
           NALVSYSLVERRVGE ALSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARDAGVPPLG
Sbjct: 487 NALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLG 546

Query: 547 SNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAW 606
           SNVTLQVFVLDENDNAPALLA  AG  GGAVSELVP SVG GHVVAKVRAVDADSGYNAW
Sbjct: 547 SNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAW 606

Query: 607 LSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVL 666
           LSYELQP   GA IPF VGLYTGEISTTR LDE DAPRHRLLVLVKDHGEPALT+TATVL
Sbjct: 607 LSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVL 666

Query: 667 VSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAP 726
           VSLVE+GQAPK SSRA VGAV P+AALVD+NVYLIIAICAVSSLLVLTLLLYTALRCSA 
Sbjct: 667 VSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAL 726

Query: 727 PTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQLSRE 781
           PT   CAPGKPTLVCSSAVGSWSYSQQRR RVCS E PPKTDLMAFSPSL  SR+
Sbjct: 727 PTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSRD 781


>gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo
           sapiens]
          Length = 824

 Score = 1176 bits (3043), Expect = 0.0
 Identities = 610/770 (79%), Positives = 662/770 (85%)

Query: 7   RGPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRV 66
           RG G+   LLSLLLLAAWEVGSGQL YSV EEAKHGTFVGRIAQDLGLEL ELVPRLFRV
Sbjct: 7   RGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRV 66

Query: 67  ASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDI 126
           ASKRHGDLLEVNLQNGILFVNSRIDRE+LCGRSAECSIH+EVIVDRPLQVFHV+VEVKDI
Sbjct: 67  ASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDI 126

Query: 127 NDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKK 186
           NDNPP+F    + +   ES  LDS FPLEGASDADIGVN+LL+Y LS +E F L I+   
Sbjct: 127 NDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQAND 186

Query: 187 DKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPS 246
           + S    LVL K LDRE+T ++NLLL+  DGGKPELTG+VQI I VLDVNDN P F +  
Sbjct: 187 ELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSV 246

Query: 247 YKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYG 306
           YKV L EN  N T V++LNASD DEG N EI Y +   +  + +  F+I+P +GEIR  G
Sbjct: 247 YKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKG 306

Query: 307 ELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVG 366
           +LD+EE  +YEIQV A DKG PSM+GH  + ++++D+NDN PEV +TSLSLP+ E+A +G
Sbjct: 307 KLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLG 366

Query: 367 TVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVT 426
           TVIALI+VSDRDSG NG V CSLTPHVPFKLVST+KNYYSLVLDSALDRESVSAYELVVT
Sbjct: 367 TVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVT 426

Query: 427 ARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQK 486
           ARDGGSPSLWAT  VS+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQ+
Sbjct: 427 ARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQE 486

Query: 487 NALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLG 546
           NALVSYSLVERRVGE ALSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLG
Sbjct: 487 NALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLG 546

Query: 547 SNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAW 606
           SNVTLQVFVLDENDNAPALLA  AG+A GAVSELVP SVGAGHVVAKVRAVDADSGYNAW
Sbjct: 547 SNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAW 606

Query: 607 LSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVL 666
           LSYELQ     A IPF VGLYTGEISTTR LDEAD+PRHRLLVLVKDHGEPALT+TATVL
Sbjct: 607 LSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVL 666

Query: 667 VSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAP 726
           VSLVE+GQAPK SSRA VGA   EA LVD+NVYLIIAICAVSSLLVLT+LLYTALRCS P
Sbjct: 667 VSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVP 726

Query: 727 PTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776
           PT    APGKPTLVCSSAVGSWSYSQQRRQRVCS E PPKTDLMAFSPSL
Sbjct: 727 PTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSL 776


>gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens]
          Length = 948

 Score = 1176 bits (3043), Expect = 0.0
 Identities = 610/770 (79%), Positives = 662/770 (85%)

Query: 7   RGPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRV 66
           RG G+   LLSLLLLAAWEVGSGQL YSV EEAKHGTFVGRIAQDLGLEL ELVPRLFRV
Sbjct: 7   RGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRV 66

Query: 67  ASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDI 126
           ASKRHGDLLEVNLQNGILFVNSRIDRE+LCGRSAECSIH+EVIVDRPLQVFHV+VEVKDI
Sbjct: 67  ASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDI 126

Query: 127 NDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKK 186
           NDNPP+F    + +   ES  LDS FPLEGASDADIGVN+LL+Y LS +E F L I+   
Sbjct: 127 NDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQAND 186

Query: 187 DKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPS 246
           + S    LVL K LDRE+T ++NLLL+  DGGKPELTG+VQI I VLDVNDN P F +  
Sbjct: 187 ELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSV 246

Query: 247 YKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYG 306
           YKV L EN  N T V++LNASD DEG N EI Y +   +  + +  F+I+P +GEIR  G
Sbjct: 247 YKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKG 306

Query: 307 ELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVG 366
           +LD+EE  +YEIQV A DKG PSM+GH  + ++++D+NDN PEV +TSLSLP+ E+A +G
Sbjct: 307 KLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLG 366

Query: 367 TVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVT 426
           TVIALI+VSDRDSG NG V CSLTPHVPFKLVST+KNYYSLVLDSALDRESVSAYELVVT
Sbjct: 367 TVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVT 426

Query: 427 ARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQK 486
           ARDGGSPSLWAT  VS+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQ+
Sbjct: 427 ARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQE 486

Query: 487 NALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLG 546
           NALVSYSLVERRVGE ALSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLG
Sbjct: 487 NALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLG 546

Query: 547 SNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAW 606
           SNVTLQVFVLDENDNAPALLA  AG+A GAVSELVP SVGAGHVVAKVRAVDADSGYNAW
Sbjct: 547 SNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAW 606

Query: 607 LSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVL 666
           LSYELQ     A IPF VGLYTGEISTTR LDEAD+PRHRLLVLVKDHGEPALT+TATVL
Sbjct: 607 LSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVL 666

Query: 667 VSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAP 726
           VSLVE+GQAPK SSRA VGA   EA LVD+NVYLIIAICAVSSLLVLT+LLYTALRCS P
Sbjct: 667 VSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVP 726

Query: 727 PTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776
           PT    APGKPTLVCSSAVGSWSYSQQRRQRVCS E PPKTDLMAFSPSL
Sbjct: 727 PTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSL 776


>gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score = 1169 bits (3025), Expect = 0.0
 Identities = 605/768 (78%), Positives = 657/768 (85%)

Query: 9   PGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68
           PG+Q LLLSLLLLAA EVGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFRVAS
Sbjct: 9   PGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68

Query: 69  KRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIND 128
           KRHGDLLEVNLQNGILFVNSRIDRE+LCGRSAECSIHLEVIVDRPLQVFHV+VEVKDIND
Sbjct: 69  KRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKDIND 128

Query: 129 NPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDK 188
           N PVF    + + +SES    S F LEGASDADIG NSLLTY+L   E F L +K   ++
Sbjct: 129 NAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRNDEE 188

Query: 189 SILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYK 248
                LVL+K L+RE TPK  LL+  IDGGKPELTG+ Q++ITVLDVNDN PAF++  YK
Sbjct: 189 IKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIYK 248

Query: 249 VVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGEL 308
           V L EN  N T V+ +NA+D DEG+N +I+Y     +       F ++P  G+I + G +
Sbjct: 249 VRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGNI 308

Query: 309 DFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTV 368
           DFEE+ +YEIQV A DKG P M+ H  VL+E++D+NDNVPE+++ SLSLPV ED+ + TV
Sbjct: 309 DFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSPLSTV 368

Query: 369 IALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTAR 428
           IALISVSDRDSG NGQV CSLTPHVPFKLVST+KNYYSLVLDS LDRESVSAYELVVTAR
Sbjct: 369 IALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVVTAR 428

Query: 429 DGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNA 488
           DGGSPSLWATA VSVEVADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSA DADAQ+NA
Sbjct: 429 DGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADAQENA 488

Query: 489 LVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548
           LVSYSLVERRVGE ALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN
Sbjct: 489 LVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548

Query: 549 VTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLS 608
           VTLQVFVLDENDNAPALL    G  GGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLS
Sbjct: 549 VTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLS 608

Query: 609 YELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLVS 668
           YELQP   GA IPF VGLYTGEISTTR LDE DAPRHRLLVLVKDHGEP+LT+TATVLVS
Sbjct: 609 YELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLTATATVLVS 668

Query: 669 LVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728
           LVE+GQAPK SS+AS GA  PEAALVD+NVYLI+AICAVSSLLVLTLLLYTALRCSAPPT
Sbjct: 669 LVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTALRCSAPPT 728

Query: 729 VSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776
              C PGKPTLVCSSAVGSWSYSQQR+QRVCS E  PKTDLMAFSPSL
Sbjct: 729 EGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSL 776


>gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo
           sapiens]
          Length = 824

 Score = 1169 bits (3025), Expect = 0.0
 Identities = 605/768 (78%), Positives = 657/768 (85%)

Query: 9   PGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68
           PG+Q LLLSLLLLAA EVGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFRVAS
Sbjct: 9   PGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68

Query: 69  KRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIND 128
           KRHGDLLEVNLQNGILFVNSRIDRE+LCGRSAECSIHLEVIVDRPLQVFHV+VEVKDIND
Sbjct: 69  KRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKDIND 128

Query: 129 NPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDK 188
           N PVF    + + +SES    S F LEGASDADIG NSLLTY+L   E F L +K   ++
Sbjct: 129 NAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRNDEE 188

Query: 189 SILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYK 248
                LVL+K L+RE TPK  LL+  IDGGKPELTG+ Q++ITVLDVNDN PAF++  YK
Sbjct: 189 IKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIYK 248

Query: 249 VVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGEL 308
           V L EN  N T V+ +NA+D DEG+N +I+Y     +       F ++P  G+I + G +
Sbjct: 249 VRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGNI 308

Query: 309 DFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTV 368
           DFEE+ +YEIQV A DKG P M+ H  VL+E++D+NDNVPE+++ SLSLPV ED+ + TV
Sbjct: 309 DFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSPLSTV 368

Query: 369 IALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTAR 428
           IALISVSDRDSG NGQV CSLTPHVPFKLVST+KNYYSLVLDS LDRESVSAYELVVTAR
Sbjct: 369 IALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVVTAR 428

Query: 429 DGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNA 488
           DGGSPSLWATA VSVEVADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSA DADAQ+NA
Sbjct: 429 DGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADAQENA 488

Query: 489 LVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548
           LVSYSLVERRVGE ALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN
Sbjct: 489 LVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548

Query: 549 VTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLS 608
           VTLQVFVLDENDNAPALL    G  GGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLS
Sbjct: 549 VTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLS 608

Query: 609 YELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLVS 668
           YELQP   GA IPF VGLYTGEISTTR LDE DAPRHRLLVLVKDHGEP+LT+TATVLVS
Sbjct: 609 YELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLTATATVLVS 668

Query: 669 LVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728
           LVE+GQAPK SS+AS GA  PEAALVD+NVYLI+AICAVSSLLVLTLLLYTALRCSAPPT
Sbjct: 669 LVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTALRCSAPPT 728

Query: 729 VSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776
              C PGKPTLVCSSAVGSWSYSQQR+QRVCS E  PKTDLMAFSPSL
Sbjct: 729 EGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSL 776


>gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens]
          Length = 937

 Score = 1169 bits (3023), Expect = 0.0
 Identities = 608/786 (77%), Positives = 656/786 (83%), Gaps = 2/786 (0%)

Query: 3   IIGPRG--PGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELV 60
           ++ P G  PG + LLL +++LAAWE G GQLHYSV EEAKHG FVGRIAQDLGLELAELV
Sbjct: 1   MVCPNGYDPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELV 60

Query: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLFR   K  GDLLEVNLQNGILFVNSRIDRE+LCGRSAECSIHLEVIV+RPLQVFHVD
Sbjct: 61  PRLFRAVCKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVD 120

Query: 121 VEVKDINDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFEL 180
           VEVKDINDNPPVF   ++ + ++ES PLDS FPLEGASDADIG N+LLTY LS NE F L
Sbjct: 121 VEVKDINDNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180

Query: 181 KIKTKKDKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGP 240
            + T   +     LVLRKLLDRE+TP+L+LLL   DGGKPELTG+VQ+ ITVLD NDN P
Sbjct: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240

Query: 241 AFDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTG 300
            FD+  Y V L ENV   T VI  NASD DEGLNG+I Y     +    K  F ++P +G
Sbjct: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300

Query: 301 EIRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQ 360
            I + G +DFEE+ A++I V A+DKG P +AGH  VLVEV+DVNDN P++ +TSLSLP+ 
Sbjct: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIP 360

Query: 361 EDAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420
           EDAQ GTVI LISV DRD G NGQV CSLTP VPFKLVST+KNYYSLVLDSALDRESVSA
Sbjct: 361 EDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480
           YELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA 
Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAG 480

Query: 481 DADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQKNALVSYSLVE RVGE ALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA
Sbjct: 481 DADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALLA   G  GGAV ELVPRSVGAGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQP A GA IPF VGLYTGEISTTR LDE DAPRHRLLVLVKDHGEP+LT
Sbjct: 601 SGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLT 660

Query: 661 STATVLVSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTA 720
           +TATVLVSLVE+GQAPK SSRAS+G   PE  LVD+NVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSAPPTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQLSR 780
           LRCSAP +   C+  KPTLVCSSAVGSWS+SQQRRQRVCS E PPKTDLMAFSPSL    
Sbjct: 721 LRCSAPSSEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP 780

Query: 781 EDCLNP 786
               NP
Sbjct: 781 SSTDNP 786


>gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo
           sapiens]
          Length = 789

 Score = 1167 bits (3020), Expect = 0.0
 Identities = 606/776 (78%), Positives = 654/776 (84%), Gaps = 2/776 (0%)

Query: 3   IIGPRG--PGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELV 60
           ++ P G  PG + LLL +++LAAWE G GQLHYSV EEAKHG FVGRIAQDLGLELAELV
Sbjct: 1   MVCPNGYDPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELV 60

Query: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLFR   K  GDLLEVNLQNGILFVNSRIDRE+LCGRSAECSIHLEVIV+RPLQVFHVD
Sbjct: 61  PRLFRAVCKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVD 120

Query: 121 VEVKDINDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFEL 180
           VEVKDINDNPPVF   ++ + ++ES PLDS FPLEGASDADIG N+LLTY LS NE F L
Sbjct: 121 VEVKDINDNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180

Query: 181 KIKTKKDKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGP 240
            + T   +     LVLRKLLDRE+TP+L+LLL   DGGKPELTG+VQ+ ITVLD NDN P
Sbjct: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240

Query: 241 AFDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTG 300
            FD+  Y V L ENV   T VI  NASD DEGLNG+I Y     +    K  F ++P +G
Sbjct: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300

Query: 301 EIRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQ 360
            I + G +DFEE+ A++I V A+DKG P +AGH  VLVEV+DVNDN P++ +TSLSLP+ 
Sbjct: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIP 360

Query: 361 EDAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420
           EDAQ GTVI LISV DRD G NGQV CSLTP VPFKLVST+KNYYSLVLDSALDRESVSA
Sbjct: 361 EDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480
           YELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA 
Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAG 480

Query: 481 DADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQKNALVSYSLVE RVGE ALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA
Sbjct: 481 DADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALLA   G  GGAV ELVPRSVGAGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQP A GA IPF VGLYTGEISTTR LDE DAPRHRLLVLVKDHGEP+LT
Sbjct: 601 SGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLT 660

Query: 661 STATVLVSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTA 720
           +TATVLVSLVE+GQAPK SSRAS+G   PE  LVD+NVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSAPPTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776
           LRCSAP +   C+  KPTLVCSSAVGSWS+SQQRRQRVCS E PPKTDLMAFSPSL
Sbjct: 721 LRCSAPSSEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSL 776


>gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 807

 Score = 1161 bits (3004), Expect = 0.0
 Identities = 603/779 (77%), Positives = 661/779 (84%)

Query: 1   MVIIGPRGPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELV 60
           MV     G G++ LLL LLLLAAWEVGSGQLHYS+ EEAKHGTFVGR+AQDLGLELAELV
Sbjct: 1   MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60

Query: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLFRVASK H DLLEVNLQNGILFVNSRIDRE+LC  SAECSIHLE+I DRPLQVFHV+
Sbjct: 61  PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120

Query: 121 VEVKDINDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFEL 180
           V+VKDINDNPPVFR REQ + + ES  L+S FP+EGA+DADIG N+LLTY LS ++ F L
Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180

Query: 181 KIKTKKDKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGP 240
            ++   + S    L LRK LDRE+TP+L+LLL   DGGKPEL G+V++ ITVLDVNDN P
Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240

Query: 241 AFDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTG 300
            FD+  Y+V L E   N T V  LNASD DEG+NGE+ +     +    +  F ++  +G
Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300

Query: 301 EIRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQ 360
           EIR+  +LD+EE  +YEIQV A+DKG P M+ H  VLV+VLDVNDN PE+ VTSL LP++
Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360

Query: 361 EDAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420
           EDA + TVIALI+VSDRDSGANGQV CSL PHVPFKLVST+KNYYSLVLDSALDRES+S 
Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420

Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480
           YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA 
Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQ+NALVSYSLVERRVGE ALS+YVSVHAESGKVYALQPLDHEELELLQFQVSARDA
Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALLA   G   GAVSELVPR VGAGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQPAA GA IPF VGLYTGEISTTR+LDEAD  R+RLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT 660

Query: 661 STATVLVSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTA 720
           +TATVLVSLVE+GQAPK SSRASVG   PEAALVD+NVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSAPPTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQLS 779
           LRCS PPT     PGKPTLVCSSA+GSWS SQQRRQRVCS+E PPKTDLMAFSP L  S
Sbjct: 721 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPS 779


>gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score = 1161 bits (3004), Expect = 0.0
 Identities = 603/779 (77%), Positives = 661/779 (84%)

Query: 1   MVIIGPRGPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELV 60
           MV     G G++ LLL LLLLAAWEVGSGQLHYS+ EEAKHGTFVGR+AQDLGLELAELV
Sbjct: 1   MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60

Query: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLFRVASK H DLLEVNLQNGILFVNSRIDRE+LC  SAECSIHLE+I DRPLQVFHV+
Sbjct: 61  PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120

Query: 121 VEVKDINDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFEL 180
           V+VKDINDNPPVFR REQ + + ES  L+S FP+EGA+DADIG N+LLTY LS ++ F L
Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180

Query: 181 KIKTKKDKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGP 240
            ++   + S    L LRK LDRE+TP+L+LLL   DGGKPEL G+V++ ITVLDVNDN P
Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240

Query: 241 AFDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTG 300
            FD+  Y+V L E   N T V  LNASD DEG+NGE+ +     +    +  F ++  +G
Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300

Query: 301 EIRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQ 360
           EIR+  +LD+EE  +YEIQV A+DKG P M+ H  VLV+VLDVNDN PE+ VTSL LP++
Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360

Query: 361 EDAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420
           EDA + TVIALI+VSDRDSGANGQV CSL PHVPFKLVST+KNYYSLVLDSALDRES+S 
Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420

Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480
           YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA 
Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQ+NALVSYSLVERRVGE ALS+YVSVHAESGKVYALQPLDHEELELLQFQVSARDA
Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALLA   G   GAVSELVPR VGAGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQPAA GA IPF VGLYTGEISTTR+LDEAD  R+RLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT 660

Query: 661 STATVLVSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTA 720
           +TATVLVSLVE+GQAPK SSRASVG   PEAALVD+NVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSAPPTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQLS 779
           LRCS PPT     PGKPTLVCSSA+GSWS SQQRRQRVCS+E PPKTDLMAFSP L  S
Sbjct: 721 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPS 779


>gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens]
          Length = 936

 Score = 1157 bits (2993), Expect = 0.0
 Identities = 600/785 (76%), Positives = 659/785 (83%)

Query: 2   VIIGPRGPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVP 61
           ++   RG    RLLL  LLLA W+ GSGQLHYS+ EEAKHGTFVGRIAQDLGLELAELVP
Sbjct: 1   MVYSRRGSLGSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVP 60

Query: 62  RLFRVASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDV 121
           RLFRVASK  GDLLEVNLQNGILFVNSRIDRE+LC R AECSIHLEVIVDRPLQVFHV+V
Sbjct: 61  RLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEV 120

Query: 122 EVKDINDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELK 181
            VKDINDNPP F  +EQ++ + ES   DS FPLEGASD DIG N+ L Y L+ NE F+L 
Sbjct: 121 AVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLD 180

Query: 182 IKTKKDKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPA 241
           +KT ++++   ELVLRK LDRE+T +  LL++  DGGKPELTG+VQ+ I VLD NDN P 
Sbjct: 181 VKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPE 240

Query: 242 FDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGE 301
           FDK  Y V L EN  + T VI+LNASD DEG+N EI Y    ++    K  F IN +TGE
Sbjct: 241 FDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGE 300

Query: 302 IRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQE 361
           I++ GELD+E+ N+YEI ++A+DK    ++GH  V+V++LDVNDN PE+ +T+L LPV+E
Sbjct: 301 IKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKE 360

Query: 362 DAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAY 421
           DA + TVIALISVSDRDSGANGQV CSL PHVPFKLVST+KNYYSLVLDSALDRESVS Y
Sbjct: 361 DAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVY 420

Query: 422 ELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWD 481
           ELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSA D
Sbjct: 421 ELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARD 480

Query: 482 ADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAG 541
           ADAQ+NALVSYSLVERRVGE  LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAG
Sbjct: 481 ADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAG 540

Query: 542 VPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADS 601
           VPPLGSNVTLQVFVLDENDNAPALL    G  GGAVSELVPRSVGAGHVVAKVRAVD DS
Sbjct: 541 VPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDS 600

Query: 602 GYNAWLSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTS 661
           GYNAWLSYELQPA   A IPF VGLYTGEISTTR LDE +APRHRLLVLVKDHGEP LT+
Sbjct: 601 GYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTA 660

Query: 662 TATVLVSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTAL 721
           TATVLVSLVE+GQAPK SSRAS GAV PEAALVD+NVYLIIAICAVSSLLVLTLLLYTAL
Sbjct: 661 TATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTAL 720

Query: 722 RCSAPPTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQLSRE 781
           RCSA PT + C  GKPTL+CSSAVGSWSYSQQRRQRVCS E+PPKTDLMAFSPSL     
Sbjct: 721 RCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPT 780

Query: 782 DCLNP 786
              NP
Sbjct: 781 STDNP 785


>gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo
           sapiens]
          Length = 816

 Score = 1156 bits (2991), Expect = 0.0
 Identities = 598/775 (77%), Positives = 657/775 (84%)

Query: 2   VIIGPRGPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVP 61
           ++   RG    RLLL  LLLA W+ GSGQLHYS+ EEAKHGTFVGRIAQDLGLELAELVP
Sbjct: 1   MVYSRRGSLGSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVP 60

Query: 62  RLFRVASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDV 121
           RLFRVASK  GDLLEVNLQNGILFVNSRIDRE+LC R AECSIHLEVIVDRPLQVFHV+V
Sbjct: 61  RLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEV 120

Query: 122 EVKDINDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELK 181
            VKDINDNPP F  +EQ++ + ES   DS FPLEGASD DIG N+ L Y L+ NE F+L 
Sbjct: 121 AVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLD 180

Query: 182 IKTKKDKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPA 241
           +KT ++++   ELVLRK LDRE+T +  LL++  DGGKPELTG+VQ+ I VLD NDN P 
Sbjct: 181 VKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPE 240

Query: 242 FDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGE 301
           FDK  Y V L EN  + T VI+LNASD DEG+N EI Y    ++    K  F IN +TGE
Sbjct: 241 FDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGE 300

Query: 302 IRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQE 361
           I++ GELD+E+ N+YEI ++A+DK    ++GH  V+V++LDVNDN PE+ +T+L LPV+E
Sbjct: 301 IKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKE 360

Query: 362 DAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAY 421
           DA + TVIALISVSDRDSGANGQV CSL PHVPFKLVST+KNYYSLVLDSALDRESVS Y
Sbjct: 361 DAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVY 420

Query: 422 ELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWD 481
           ELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSA D
Sbjct: 421 ELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARD 480

Query: 482 ADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAG 541
           ADAQ+NALVSYSLVERRVGE  LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAG
Sbjct: 481 ADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAG 540

Query: 542 VPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADS 601
           VPPLGSNVTLQVFVLDENDNAPALL    G  GGAVSELVPRSVGAGHVVAKVRAVD DS
Sbjct: 541 VPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDS 600

Query: 602 GYNAWLSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTS 661
           GYNAWLSYELQPA   A IPF VGLYTGEISTTR LDE +APRHRLLVLVKDHGEP LT+
Sbjct: 601 GYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTA 660

Query: 662 TATVLVSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTAL 721
           TATVLVSLVE+GQAPK SSRAS GAV PEAALVD+NVYLIIAICAVSSLLVLTLLLYTAL
Sbjct: 661 TATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTAL 720

Query: 722 RCSAPPTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776
           RCSA PT + C  GKPTL+CSSAVGSWSYSQQRRQRVCS E+PPKTDLMAFSPSL
Sbjct: 721 RCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSL 775


>gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens]
          Length = 842

 Score = 1150 bits (2975), Expect = 0.0
 Identities = 599/768 (77%), Positives = 648/768 (84%)

Query: 9   PGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68
           P  Q LLLSLL+LA W VGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELVPRLF++ S
Sbjct: 9   PEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDS 68

Query: 69  KRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIND 128
           K  GDLLEVNLQNGILFVNSRIDRE+LCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIND
Sbjct: 69  KGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIND 128

Query: 129 NPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDK 188
           NPPVF   ++ + ++ES PLDS FPLEGASDADIG N+LLTY LS NE F L + T   +
Sbjct: 129 NPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQ 188

Query: 189 SILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYK 248
                LVLRKLLDRE+TP+L+LLL   DGGKPELTG+VQ+ ITVLD NDN P FD+  Y 
Sbjct: 189 VKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYT 248

Query: 249 VVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGEL 308
           V L ENV   T VI  NASD DEGLNG+I Y     +    K  F ++P +G I + G +
Sbjct: 249 VKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHM 308

Query: 309 DFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTV 368
           DFEE+ A++I V A+DKG P +AGH  +LVEV+DVNDN P++ + +LS+PV+EDAQ+GTV
Sbjct: 309 DFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTV 368

Query: 369 IALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTAR 428
           IALISV D D+ ANGQV CSLTPHVPFKLVSTYKNYYSLVLD ALDRESVSAYELVVTAR
Sbjct: 369 IALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTAR 428

Query: 429 DGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNA 488
           DGGSPSLWATARVSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQ+NA
Sbjct: 429 DGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENA 488

Query: 489 LVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548
           LVSYSLVERR+GE +LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN
Sbjct: 489 LVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548

Query: 549 VTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLS 608
           VTLQVFVLDENDNAPALL        GAVSE+V RSVGAG VV KVRAVDADSGYNAWLS
Sbjct: 549 VTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLS 608

Query: 609 YELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLVS 668
           YELQP    A IPF VGLYTGEISTTR LDE DAPR RLLVLVKDHGEPALT+TATVLVS
Sbjct: 609 YELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVS 668

Query: 669 LVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728
           LVE+GQAPK+SSRASVGA  PE  LVD+NVYLIIAICAVSSLLVLTLLLYT LRCSA PT
Sbjct: 669 LVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMPT 728

Query: 729 VSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776
              CAPGKPTLVCSSAVGSWSYSQQRRQRVCS E   KTDLMAFSP L
Sbjct: 729 EGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGL 776


>gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo
           sapiens]
          Length = 950

 Score = 1150 bits (2975), Expect = 0.0
 Identities = 599/768 (77%), Positives = 648/768 (84%)

Query: 9   PGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68
           P  Q LLLSLL+LA W VGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELVPRLF++ S
Sbjct: 9   PEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDS 68

Query: 69  KRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIND 128
           K  GDLLEVNLQNGILFVNSRIDRE+LCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIND
Sbjct: 69  KGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIND 128

Query: 129 NPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDK 188
           NPPVF   ++ + ++ES PLDS FPLEGASDADIG N+LLTY LS NE F L + T   +
Sbjct: 129 NPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQ 188

Query: 189 SILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYK 248
                LVLRKLLDRE+TP+L+LLL   DGGKPELTG+VQ+ ITVLD NDN P FD+  Y 
Sbjct: 189 VKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYT 248

Query: 249 VVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGEL 308
           V L ENV   T VI  NASD DEGLNG+I Y     +    K  F ++P +G I + G +
Sbjct: 249 VKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHM 308

Query: 309 DFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTV 368
           DFEE+ A++I V A+DKG P +AGH  +LVEV+DVNDN P++ + +LS+PV+EDAQ+GTV
Sbjct: 309 DFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTV 368

Query: 369 IALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTAR 428
           IALISV D D+ ANGQV CSLTPHVPFKLVSTYKNYYSLVLD ALDRESVSAYELVVTAR
Sbjct: 369 IALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTAR 428

Query: 429 DGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNA 488
           DGGSPSLWATARVSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQ+NA
Sbjct: 429 DGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENA 488

Query: 489 LVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548
           LVSYSLVERR+GE +LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN
Sbjct: 489 LVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548

Query: 549 VTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLS 608
           VTLQVFVLDENDNAPALL        GAVSE+V RSVGAG VV KVRAVDADSGYNAWLS
Sbjct: 549 VTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLS 608

Query: 609 YELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLVS 668
           YELQP    A IPF VGLYTGEISTTR LDE DAPR RLLVLVKDHGEPALT+TATVLVS
Sbjct: 609 YELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVS 668

Query: 669 LVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728
           LVE+GQAPK+SSRASVGA  PE  LVD+NVYLIIAICAVSSLLVLTLLLYT LRCSA PT
Sbjct: 669 LVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMPT 728

Query: 729 VSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776
              CAPGKPTLVCSSAVGSWSYSQQRRQRVCS E   KTDLMAFSP L
Sbjct: 729 EGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGL 776


>gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo
           sapiens]
          Length = 685

 Score =  806 bits (2081), Expect = 0.0
 Identities = 415/525 (79%), Positives = 446/525 (84%)

Query: 10  GSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69
           G Q LLLSLLLLAAWEVGSGQLHYSVYEEA+HGTFVGRIAQDLGLELAELV RLFRVASK
Sbjct: 9   GVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASK 68

Query: 70  RHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDN 129
           RHGDLLEVNLQNGILFVNSRIDRE+LCGRS ECSIHLEVIVDRPLQVFHVDVEVKDINDN
Sbjct: 69  RHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDN 128

Query: 130 PPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDKS 189
           PP F   EQK+ + ES  LDS FPLEGASDAD+G N+LLTY LS NE F L I  KKDK 
Sbjct: 129 PPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKD 188

Query: 190 ILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYKV 249
             P LVLRKLLDRE+ P+L LLL   DGGKPE TGSV + I VLD NDN P FD+P Y+V
Sbjct: 189 KFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEV 248

Query: 250 VLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGELD 309
            + EN  N T VI+LNASD DEG+N E+ Y    ++P + +  F IN  TGEI++   +D
Sbjct: 249 KMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAID 308

Query: 310 FEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTVI 369
           FE++N YEI V+  DKG P M GH  VLVE+LD NDN PEV+VTSLSLPV+EDAQVGTVI
Sbjct: 309 FEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVI 368

Query: 370 ALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARD 429
           ALISVSD DSGANGQV CSLTPHVPFKLVSTYKNYYSLVLDSALDRE VSAYELVVTARD
Sbjct: 369 ALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARD 428

Query: 430 GGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNAL 489
           GGSP LWATA VSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSAWDADAQ+NAL
Sbjct: 429 GGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENAL 488

Query: 490 VSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQ 534
           VSYSLVERR+GE +LSSYVSVHAESGKVYALQPLDHEELELLQFQ
Sbjct: 489 VSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQ 533



 Score =  142 bits (357), Expect = 2e-33
 Identities = 116/398 (29%), Positives = 178/398 (44%), Gaps = 31/398 (7%)

Query: 292 MFSINPDTGEIRIYGELDFEENNAYEIQVNA-----IDKGIPSMAGHSMVLVEVLDVNDN 346
           +  +N   G + +   +D EE     ++ +      +D+  P    H  V VEV D+NDN
Sbjct: 73  LLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDR--PLQVFH--VDVEVKDINDN 128

Query: 347 VPEVMVTSLSLPVQEDAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKN--- 403
            P   VT   L + E   + +   L   SD D G N  +   L+P+  F L    K    
Sbjct: 129 PPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKD 188

Query: 404 -YYSLVLDSALDRESVSAYELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTV 462
            +  LVL   LDRE     +L++TA DGG P    +  + + V D NDNAP F +P Y V
Sbjct: 189 KFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEV 248

Query: 463 FVKENNPPGCHIFTVSAWDADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQP 522
            + EN      +  ++A D+D   N  + YS     +    +     ++  +G++     
Sbjct: 249 KMYENQVNQTLVIRLNASDSDEGINKEMMYSFSS--LVPPTIRRKFWINERTGEIKVNDA 306

Query: 523 LDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVP 582
           +D E+    +  V   D G PP+  + T+ V +LDENDN+P ++ T       ++S  V 
Sbjct: 307 IDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVT-------SLSLPVK 359

Query: 583 RSVGAGHVVAKVRAVDADSGYNAWLSYELQPAAVGAHIPFH-VGLYTGEISTT--RILDE 639
                G V+A +   D DSG N  ++  L P     H+PF  V  Y    S      LD 
Sbjct: 360 EDAQVGTVIALISVSDHDSGANGQVTCSLTP-----HVPFKLVSTYKNYYSLVLDSALDR 414

Query: 640 ADAPRHRLLVLVKDHGEPALTSTATVLVSLVE-NGQAP 676
                + L+V  +D G P L +TA+V V + + N  AP
Sbjct: 415 ERVSAYELVVTARDGGSPPLWATASVSVEVADVNDNAP 452



 Score =  142 bits (357), Expect = 2e-33
 Identities = 115/400 (28%), Positives = 179/400 (44%), Gaps = 28/400 (7%)

Query: 228 IQITVLDVNDNGPAFDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKM---- 283
           + + V D+NDN P F     K+ + E+   D+R     ASD D G N  ++Y +      
Sbjct: 118 VDVEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYF 177

Query: 284 ---ILPVSEKCMFSINPDTGEIRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEV 340
              I+   +K  F +      + +   LD EEN   ++ + A D G P   G   +L+ V
Sbjct: 178 VLDIINKKDKDKFPV------LVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILV 231

Query: 341 LDVNDNVPEVMVTSLSLPVQEDAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVST 400
           LD NDN P        + + E+    T++  ++ SD D G N +++ S +  VP  +   
Sbjct: 232 LDANDNAPIFDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRK 291

Query: 401 Y---KNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQ 457
           +   +    + ++ A+D E  + YE+ V   D G+P +     V VE+ D NDN+P    
Sbjct: 292 FWINERTGEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIV 351

Query: 458 PEYTVFVKENNPPGCHIFTVSAWDADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKV 517
              ++ VKE+   G  I  +S  D D+  N  V+ SL       H     VS +     +
Sbjct: 352 TSLSLPVKEDAQVGTVIALISVSDHDSGANGQVTCSLTP-----HVPFKLVSTYKNYYSL 406

Query: 518 YALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAV 577
                LD E +   +  V+ARD G PPL +  ++ V V D NDNAPA        A    
Sbjct: 407 VLDSALDRERVSAYELVVTARDGGSPPLWATASVSVEVADVNDNAPAF-------AQSEY 459

Query: 578 SELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPAAVG 617
           +  V  +   G  +  V A DAD+  NA +SY L    +G
Sbjct: 460 TVFVKENNPPGCHIFTVSAWDADAQENALVSYSLVERRLG 499


>gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo
           sapiens]
          Length = 686

 Score =  771 bits (1992), Expect = 0.0
 Identities = 400/525 (76%), Positives = 441/525 (84%)

Query: 10  GSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69
           G Q LLL LLLLAAW+VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFR+ASK
Sbjct: 10  GKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASK 69

Query: 70  RHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDN 129
              DLLEVNLQNGILFVNSRIDRE+LCGRSAECSIHLEVIVDRPLQVFHVDVEV+DINDN
Sbjct: 70  DREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDN 129

Query: 130 PPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDKS 189
           PP+F   EQ+V + ES   DS FPLEGASDAD+G NS+LTY LS +E F L +K   D +
Sbjct: 130 PPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDN 189

Query: 190 ILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYKV 249
               L+L+K LDRE+ P  NL L   DGGKPELTG+VQ+ +TVLDVNDN P F++  Y+V
Sbjct: 190 KQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249

Query: 250 VLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGELD 309
            + EN  N T VI+LNASD DEG NG ISY    ++       FSI+ +TGEI I G LD
Sbjct: 250 RIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLD 309

Query: 310 FEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTVI 369
           FE+ N Y+I ++A DKG P MAGH  VLV +LD NDNVPE+ +TSLSLPV+EDAQ GTVI
Sbjct: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369

Query: 370 ALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARD 429
           ALISV+D DSGANGQV CSLTPHVPFKLVST+KNYYSLVLDSALDRESVSAYELVVTARD
Sbjct: 370 ALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429

Query: 430 GGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNAL 489
           GGSPSLWATA +SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL
Sbjct: 430 GGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489

Query: 490 VSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQ 534
           VSYSLVERRVGE ALSSY+SVHAESGKVYALQPLDHEELELLQFQ
Sbjct: 490 VSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQ 534



 Score =  157 bits (396), Expect = 5e-38
 Identities = 116/350 (33%), Positives = 166/350 (47%), Gaps = 28/350 (8%)

Query: 338 VEVLDVNDNVPEVMVTSLSLPVQEDAQVGTVIALISVSDRDSGANGQVICSLTPHVPF-- 395
           VEV D+NDN P   V    + + E     +V  L   SD D G+N  +   L+    F  
Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180

Query: 396 --KLVSTYKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWATARVSVEVADVNDNAP 453
             K+ S       L+L  +LDRE   A+ L +TA DGG P L  T ++ V V DVNDNAP
Sbjct: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240

Query: 454 AFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNALVSYS---LVERRVGEHALSSYVSV 510
            F Q EY V + EN   G  +  ++A D D   N  +SYS   LV   V +H      S+
Sbjct: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDH-----FSI 295

Query: 511 HAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLATPA 570
              +G++     LD E+  L +  + A D G PP+  + T+ V +LD+NDN P +  T  
Sbjct: 296 DRNTGEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALT-- 353

Query: 571 GSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPAAVGAHIPFH-VGLYTG 629
                ++S  V      G V+A +   D DSG N  ++  L P     H+PF  V  +  
Sbjct: 354 -----SLSLPVREDAQFGTVIALISVNDLDSGANGQVNCSLTP-----HVPFKLVSTFKN 403

Query: 630 EISTT--RILDEADAPRHRLLVLVKDHGEPALTSTATVLVSLVE-NGQAP 676
             S      LD      + L+V  +D G P+L +TA++ V + + N  AP
Sbjct: 404 YYSLVLDSALDRESVSAYELVVTARDGGSPSLWATASLSVEVADMNDNAP 453



 Score =  156 bits (395), Expect = 6e-38
 Identities = 121/395 (30%), Positives = 179/395 (45%), Gaps = 18/395 (4%)

Query: 228 IQITVLDVNDNGPAFDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKM--IL 285
           + + V D+NDN P F     +V++ E+   D+      ASD D G N  ++Y +      
Sbjct: 119 VDVEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYF 178

Query: 286 PVSEKCMFSINPDTGEIRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVND 345
            +  K     N   G + +   LD EE  A+ + + A D G P + G   +LV VLDVND
Sbjct: 179 GLDVKINSDDNKQIG-LLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVND 237

Query: 346 NVPEVMVTSLSLPVQEDAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTY---K 402
           N P    +   + + E+A  GT +  ++ SDRD GANG +  S    V   ++  +   +
Sbjct: 238 NAPTFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDR 297

Query: 403 NYYSLVLDSALDRESVSAYELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTV 462
           N   +V+   LD E  + Y++++ A D G P +     V V + D NDN P  A    ++
Sbjct: 298 NTGEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSL 357

Query: 463 FVKENNPPGCHIFTVSAWDADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQP 522
            V+E+   G  I  +S  D D+  N  V+ SL       H     VS       +     
Sbjct: 358 PVREDAQFGTVIALISVNDLDSGANGQVNCSLTP-----HVPFKLVSTFKNYYSLVLDSA 412

Query: 523 LDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVP 582
           LD E +   +  V+ARD G P L +  +L V V D NDNAPA        A    +  V 
Sbjct: 413 LDRESVSAYELVVTARDGGSPSLWATASLSVEVADMNDNAPAF-------AQPEYTVFVK 465

Query: 583 RSVGAGHVVAKVRAVDADSGYNAWLSYELQPAAVG 617
            +   G  +  V A DAD+  NA +SY L    VG
Sbjct: 466 ENNPPGCHIFTVSARDADAQENALVSYSLVERRVG 500


>gi|14165402 protocadherin alpha 1 isoform 3 precursor [Homo
           sapiens]
          Length = 686

 Score =  758 bits (1958), Expect = 0.0
 Identities = 392/534 (73%), Positives = 443/534 (82%)

Query: 1   MVIIGPRGPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELV 60
           MV     G G++ LLL LLLLAAWEVGSGQLHYS+ EEAKHGTFVGR+AQDLGLELAELV
Sbjct: 1   MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60

Query: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLFRVASK H DLLEVNLQNGILFVNSRIDRE+LC  SAECSIHLE+I DRPLQVFHV+
Sbjct: 61  PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120

Query: 121 VEVKDINDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFEL 180
           V+VKDINDNPPVFR REQ + + ES  L+S FP+EGA+DADIG N+LLTY LS ++ F L
Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180

Query: 181 KIKTKKDKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGP 240
            ++   + S    L LRK LDRE+TP+L+LLL   DGGKPEL G+V++ ITVLDVNDN P
Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240

Query: 241 AFDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTG 300
            FD+  Y+V L E   N T V  LNASD DEG+NGE+ +     +    +  F ++  +G
Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300

Query: 301 EIRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQ 360
           EIR+  +LD+EE  +YEIQV A+DKG P M+ H  VLV+VLDVNDN PE+ VTSL LP++
Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360

Query: 361 EDAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420
           EDA + TVIALI+VSDRDSGANGQV CSL PHVPFKLVST+KNYYSLVLDSALDRES+S 
Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420

Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480
           YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA 
Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQ 534
           DADAQ+NALVSYSLVERRVGE ALS+YVSVHAESGKVYALQPLDHEELELLQFQ
Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQ 534



 Score =  149 bits (376), Expect = 1e-35
 Identities = 122/402 (30%), Positives = 181/402 (45%), Gaps = 32/402 (7%)

Query: 228 IQITVLDVNDNGPAFDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPV 287
           +++ V D+NDN P F      + + E+   ++R     A+D D G N  ++Y +      
Sbjct: 119 VEVKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTL------ 172

Query: 288 SEKCMFSINPDTG---------EIRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLV 338
           S    FS++ +           E+R Y  LD EE     + + A D G P + G   +L+
Sbjct: 173 SPSDYFSLDVEASDELSKSLWLELRKY--LDREETPELHLLLTATDGGKPELQGTVELLI 230

Query: 339 EVLDVNDNVPEVMVTSLSLPVQEDAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLV 398
            VLDVNDN P        + + E    GT++  ++ SD D G NG+V+ S    +   + 
Sbjct: 231 TVLDVNDNAPLFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQ 290

Query: 399 STYKNYYS---LVLDSALDRESVSAYELVVTARDGGSPSLWATARVSVEVADVNDNAPAF 455
             +K   S   + L   LD E   +YE+ V A D GSP +    +V V+V DVNDNAP  
Sbjct: 291 EKFKVDSSSGEIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPEL 350

Query: 456 AQPEYTVFVKENNPPGCHIFTVSAWDADAQKNALVSYSLVERRVGEHALSSYVSVHAESG 515
           A     + ++E+ P    I  ++  D D+  N  V+ SL+      H     VS      
Sbjct: 351 AVTSLYLPIREDAPLSTVIALITVSDRDSGANGQVTCSLMP-----HVPFKLVSTFKNYY 405

Query: 516 KVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLATPAGSAGG 575
            +     LD E L + +  V+ARD G P L +   + V V D NDNAPA        A  
Sbjct: 406 SLVLDSALDRESLSVYELVVTARDGGSPSLWATARVSVEVADVNDNAPAF-------AQP 458

Query: 576 AVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPAAVG 617
             +  V  +   G  +  V A DAD+  NA +SY L    VG
Sbjct: 459 EYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVG 500



 Score =  145 bits (366), Expect = 1e-34
 Identities = 133/443 (30%), Positives = 198/443 (44%), Gaps = 48/443 (10%)

Query: 263 QLNASDPDEGLNG------------EISYGIKMILPVSEKC---MFSINPDTGEIRIYGE 307
           QL+ S P+E  +G            E++  +  +  V+ K    +  +N   G + +   
Sbjct: 30  QLHYSIPEEAKHGTFVGRVAQDLGLELAELVPRLFRVASKTHRDLLEVNLQNGILFVNSR 89

Query: 308 LDFEENNAYEIQVNAIDKGI---PSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQ 364
           +D EE   +  + +   + I   P    H  V V+V D+NDN P        + + E   
Sbjct: 90  IDREELCQWSAECSIHLELIADRPLQVFH--VEVKVKDINDNPPVFRGREQIIFIPESRL 147

Query: 365 VGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYS----LVLDSALDRESVSA 420
           + +   +   +D D GAN  +  +L+P   F L     +  S    L L   LDRE    
Sbjct: 148 LNSRFPIEGAADADIGANALLTYTLSPSDYFSLDVEASDELSKSLWLELRKYLDREETPE 207

Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480
             L++TA DGG P L  T  + + V DVNDNAP F Q  Y V + E    G  + T++A 
Sbjct: 208 LHLLLTATDGGKPELQGTVELLITVLDVNDNAPLFDQAVYRVHLLETTANGTLVTTLNAS 267

Query: 481 DADAQKNALVSYSL---VERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSA 537
           DAD   N  V +S    + R + E        V + SG++  +  LD+EE +  + QV A
Sbjct: 268 DADEGVNGEVVFSFDSGISRDIQEK-----FKVDSSSGEIRLIDKLDYEETKSYEIQVKA 322

Query: 538 RDAGVPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAV 597
            D G PP+ ++  + V VLD NDNAP L  T   S    + E  P S     V+A +   
Sbjct: 323 VDKGSPPMSNHCKVLVKVLDVNDNAPELAVT---SLYLPIREDAPLST----VIALITVS 375

Query: 598 DADSGYNAWLSYELQPAAVGAHIPFH-VGLYTGEISTT--RILDEADAPRHRLLVLVKDH 654
           D DSG N  ++  L P     H+PF  V  +    S      LD      + L+V  +D 
Sbjct: 376 DRDSGANGQVTCSLMP-----HVPFKLVSTFKNYYSLVLDSALDRESLSVYELVVTARDG 430

Query: 655 GEPALTSTATVLVSLVE-NGQAP 676
           G P+L +TA V V + + N  AP
Sbjct: 431 GSPSLWATARVSVEVADVNDNAP 453


>gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precursor
           [Homo sapiens]
          Length = 932

 Score =  579 bits (1493), Expect = e-165
 Identities = 311/711 (43%), Positives = 461/711 (64%), Gaps = 11/711 (1%)

Query: 14  LLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGD 73
           +LL +LL   WE G  Q+ YSV EE + G+ VG I++DLGLE  EL  R  R+  +    
Sbjct: 14  VLLGILLGTLWETGCTQIRYSVPEELEKGSRVGDISRDLGLEPRELAERGVRIIPRGRTQ 73

Query: 74  LLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPPVF 133
           L  +N ++G L    RIDRE+LC  + +C ++L+++++  ++++ V+VEV+DINDN P F
Sbjct: 74  LFALNPRSGSLVTAGRIDREELCMGAIKCQLNLDILMEDKVKIYGVEVEVRDINDNAPYF 133

Query: 134 REREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDKSILPE 193
           RE E ++ +SE+A  +  FPL  A D DIG NSL +Y LS N +F L ++   D S  PE
Sbjct: 134 RESELEIKISENAATEMRFPLPHAWDPDIGKNSLQSYELSPNTHFSLIVQNGADGSKYPE 193

Query: 194 LVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYKVVLSE 253
           LVL++ LDRE+    +L+L   DGG P  TG+ +I++ VLD NDN PAF +P Y+  + E
Sbjct: 194 LVLKRALDREEKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDNAPAFAQPEYRASVPE 253

Query: 254 NVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGELDFEEN 313
           N+   T+++ +NA+DPDEG+N E+ Y  + +   + + +F ++ ++G I   GELD EE+
Sbjct: 254 NLALGTQLLVVNATDPDEGVNAEVRYSFRYVDDKAAQ-VFKLDCNSGTISTIGELDHEES 312

Query: 314 NAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTVIALIS 373
             Y+++V A+D      +  + VL+ VLDVNDN PEV++TSL+  V E++  GT+IAL++
Sbjct: 313 GFYQMEVQAMDNA--GYSARAKVLITVLDVNDNAPEVVLTSLASSVPENSPRGTLIALLN 370

Query: 374 VSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433
           V+D+DS  NGQVIC +  ++PFKL  +Y NYYSLV D  LDRE V +Y + VTA D G+P
Sbjct: 371 VNDQDSEENGQVICFIQGNLPFKLEKSYGNYYSLVTDIVLDREQVPSYNITVTATDRGTP 430

Query: 434 SLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNALVSYS 493
            L     +S+ VAD NDN P F Q  Y+ ++ ENNP G  + +V+A D D ++NA ++YS
Sbjct: 431 PLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLVSVTAHDPDCEENAQITYS 490

Query: 494 LVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQV 553
           L E  +   +LSSYVS+++++G +YAL   D+E+   LQ +V ARD G PPL SNV+L +
Sbjct: 491 LAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVKVMARDNGHPPLSSNVSLSL 550

Query: 554 FVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQP 613
           FVLD+NDNAP +L     + G    EL PRS   G++V KV AVD DSG NAWLSY L  
Sbjct: 551 FVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLK 610

Query: 614 AAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLVSLVENG 673
           A+      F VGL+TGE+ T R L + DA +  L+V V+DHG+P L++T T+ V++ ++ 
Sbjct: 611 ASEPG--LFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADS- 667

Query: 674 QAPKTSSRASVGAVDPEA--ALVDINVYLIIAICAVSSLLVLTLLLYTALR 722
             P+    A +G+++  A     D+ +YL++A+ AVS + +  ++L  ALR
Sbjct: 668 -IPQV--LADLGSLESPANSETSDLTLYLVVAVAAVSCVFLAFVILLLALR 715


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.133    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,501,497
Number of Sequences: 37866
Number of extensions: 1363599
Number of successful extensions: 10200
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 192
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 3186
Number of HSP's gapped (non-prelim): 751
length of query: 792
length of database: 18,247,518
effective HSP length: 110
effective length of query: 682
effective length of database: 14,082,258
effective search space: 9604099956
effective search space used: 9604099956
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.