Search of human proteins with 14165390

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo
sapiens]
         (803 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo sapi...  1575   0.0  
gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens]  1566   0.0  
gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo sapi...  1387   0.0  
gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens]  1382   0.0  
gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo sapi...  1253   0.0  
gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens]  1247   0.0  
gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo sap...  1217   0.0  
gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo sapi...  1216   0.0  
gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens]  1214   0.0  
gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapi...  1214   0.0  
gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo sapi...  1212   0.0  
gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens]  1209   0.0  
gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo sap...  1208   0.0  
gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo sapi...  1206   0.0  
gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo sapi...  1206   0.0  
gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens]  1204   0.0  
gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo sapi...  1200   0.0  
gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens]  1200   0.0  
gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo sap...  1199   0.0  
gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo sapi...  1198   0.0  
gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens]  1197   0.0  
gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo sapi...  1197   0.0  
gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens]  1193   0.0  
gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo sapi...  1192   0.0  
gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo sap...  1182   0.0  
gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo sapi...  1182   0.0  
gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo sapi...  1050   0.0  
gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo sap...   795   0.0  
gi|14165402 protocadherin alpha 1 isoform 3 precursor [Homo sapi...   780   0.0  
gi|14277677 protocadherin gamma subfamily C, 3 isoform 2 precurs...   601   e-171

>gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo
           sapiens]
          Length = 803

 Score = 1575 bits (4077), Expect = 0.0
 Identities = 803/803 (100%), Positives = 803/803 (100%)

Query: 1   MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
           MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV
Sbjct: 1   MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD
Sbjct: 61  PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120

Query: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180
           VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL
Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180

Query: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240
           DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP
Sbjct: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240

Query: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300
           TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG
Sbjct: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300

Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360
           EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR
Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360

Query: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420
           EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA
Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480
           YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR
Sbjct: 421 YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDA
Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660

Query: 661 ATATVLVSLVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVLVSLVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSAPPTEGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCP 780
           LRCSAPPTEGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCP
Sbjct: 721 LRCSAPPTEGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCP 780

Query: 781 IMMGKAENQDLNEDHDAKVSEFS 803
           IMMGKAENQDLNEDHDAKVSEFS
Sbjct: 781 IMMGKAENQDLNEDHDAKVSEFS 803


>gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score = 1566 bits (4054), Expect = 0.0
 Identities = 798/798 (100%), Positives = 798/798 (100%)

Query: 1   MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
           MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV
Sbjct: 1   MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD
Sbjct: 61  PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120

Query: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180
           VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL
Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180

Query: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240
           DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP
Sbjct: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240

Query: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300
           TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG
Sbjct: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300

Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360
           EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR
Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360

Query: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420
           EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA
Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480
           YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR
Sbjct: 421 YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDA
Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660

Query: 661 ATATVLVSLVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVLVSLVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSAPPTEGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCP 780
           LRCSAPPTEGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCP
Sbjct: 721 LRCSAPPTEGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCP 780

Query: 781 IMMGKAENQDLNEDHDAK 798
           IMMGKAENQDLNEDHDAK
Sbjct: 781 IMMGKAENQDLNEDHDAK 798


>gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo
           sapiens]
          Length = 814

 Score = 1387 bits (3591), Expect = 0.0
 Identities = 710/794 (89%), Positives = 739/794 (93%)

Query: 9   LGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMAS 68
           LG   LLL LLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFR+AS
Sbjct: 9   LGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68

Query: 69  KDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDIND 128
           K   DLLEV+LQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEV+D+ND
Sbjct: 69  KRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVND 128

Query: 129 NPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDD 188
           NPP+F V++Q++ + ESR+PDS FPLEGASDADVG+NS+LTY+LSS +YF LDV   +D+
Sbjct: 129 NPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDE 188

Query: 189 NKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248
           NK + L+L+KSLDRE+APAH+LFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE
Sbjct: 189 NKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248

Query: 249 VRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNL 308
           VRIFENADNGTTVI+LNASD DEGANGAISYSFNSLV  MVIDHFSIDRNTGEIVIRGNL
Sbjct: 249 VRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNL 308

Query: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368
           DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV
Sbjct: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368

Query: 369 IALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTAR 428
           IALISVNDLDSGANGQV CSL PHVPFKLVSTFKNYYSLVLDSALDRE VSAYELVVTAR
Sbjct: 369 IALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTAR 428

Query: 429 DGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488
           DGGSPSLWATASLSVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA
Sbjct: 429 DGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488

Query: 489 LVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548
           LVSYSLVERRVGER+LSSYISVH ESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN
Sbjct: 489 LVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548

Query: 549 VTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLS 608
           VTLQVFVLDENDNAPALL PRVGGTGGA S+LVPRS+GAG VVAKVRAVDADSGYNAWLS
Sbjct: 549 VTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLS 608

Query: 609 YELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS 668
           YELQP ASS R PFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS
Sbjct: 609 YELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS 668

Query: 669 LVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728
           LVESGQAPKASSR S G  GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA PT
Sbjct: 669 LVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPT 728

Query: 729 EGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAEN 788
           EG C A KPTLVCSSAVGSWSYSQQ+ QRVCSGEGPPK DLMAFSP L P    +   E 
Sbjct: 729 EGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVDVGEE 788

Query: 789 QDLNEDHDAKVSEF 802
           QDLN DH  KVS F
Sbjct: 789 QDLNVDHGLKVSPF 802


>gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score = 1382 bits (3578), Expect = 0.0
 Identities = 707/790 (89%), Positives = 736/790 (93%)

Query: 9   LGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMAS 68
           LG   LLL LLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFR+AS
Sbjct: 9   LGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68

Query: 69  KDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDIND 128
           K   DLLEV+LQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEV+D+ND
Sbjct: 69  KRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVND 128

Query: 129 NPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDD 188
           NPP+F V++Q++ + ESR+PDS FPLEGASDADVG+NS+LTY+LSS +YF LDV   +D+
Sbjct: 129 NPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDE 188

Query: 189 NKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248
           NK + L+L+KSLDRE+APAH+LFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE
Sbjct: 189 NKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248

Query: 249 VRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNL 308
           VRIFENADNGTTVI+LNASD DEGANGAISYSFNSLV  MVIDHFSIDRNTGEIVIRGNL
Sbjct: 249 VRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNL 308

Query: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368
           DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV
Sbjct: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368

Query: 369 IALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTAR 428
           IALISVNDLDSGANGQV CSL PHVPFKLVSTFKNYYSLVLDSALDRE VSAYELVVTAR
Sbjct: 369 IALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTAR 428

Query: 429 DGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488
           DGGSPSLWATASLSVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA
Sbjct: 429 DGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488

Query: 489 LVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548
           LVSYSLVERRVGER+LSSYISVH ESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN
Sbjct: 489 LVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548

Query: 549 VTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLS 608
           VTLQVFVLDENDNAPALL PRVGGTGGA S+LVPRS+GAG VVAKVRAVDADSGYNAWLS
Sbjct: 549 VTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLS 608

Query: 609 YELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS 668
           YELQP ASS R PFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS
Sbjct: 609 YELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS 668

Query: 669 LVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728
           LVESGQAPKASSR S G  GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA PT
Sbjct: 669 LVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPT 728

Query: 729 EGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAEN 788
           EG C A KPTLVCSSAVGSWSYSQQ+ QRVCSGEGPPK DLMAFSP L P    +   E 
Sbjct: 729 EGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVDVGEE 788

Query: 789 QDLNEDHDAK 798
           QDLN DH  K
Sbjct: 789 QDLNVDHGLK 798


>gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo
           sapiens]
          Length = 824

 Score = 1253 bits (3241), Expect = 0.0
 Identities = 635/802 (79%), Positives = 702/802 (87%)

Query: 1   MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
           M+F+  +  G QCLLL LLLLAA +VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV
Sbjct: 1   MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLFR+ASK   DLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+
Sbjct: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120

Query: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180
           VEV+DINDN P+FP+  + + I ESR P S F LEGASDAD+G+NS+LTY L S+EYF L
Sbjct: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180

Query: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240
           DVK N ++ K +GL+LKK+L+RE+ P H L +TA DGGKPELTGT QL +TVLDVNDNAP
Sbjct: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240

Query: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300
            FE++ Y+VR+ ENA NGT V+ +NA+D DEG N  I+YSFN+ ++A ++  F +D   G
Sbjct: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300

Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360
           +I ++GN+DFE+   Y+I ++ATDKG+PPM+ HCTVL+ I+D NDNVPE+ + SLSLPV 
Sbjct: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360

Query: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420
           ED+   TVIALISV+D DSG NGQV CSLTPHVPFKLVSTFKNYYSLVLDS LDRESVSA
Sbjct: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480
           YELVVTARDGGSPSLWATAS+SVEVAD+NDNAPAF+Q EYTVFVKENNPPGCHIFTVSAR
Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQENALVSYSLVERRVGERALSSY+SVHAESGKVYALQPLDHEELELLQFQVSARDA
Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL PRVGG GGAVSELVPRS+GAG VVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQP    AR PFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEP+LT
Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660

Query: 661 ATATVLVSLVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVLVSLVESGQAPKASS+AS GA GPEAALVDVNVYLI+AICAVSSLLVLTLLLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSAPPTEGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCP 780
           LRCSAPPTEG C   KPTLVCSSAVGSWSYSQQR+QRVCSGEG PK DLMAFSPSL PCP
Sbjct: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780

Query: 781 IMMGKAENQDLNEDHDAKVSEF 802
           I   + E QD++ D  AKVS F
Sbjct: 781 ISRDREEKQDVDVDLSAKVSNF 802


>gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score = 1247 bits (3227), Expect = 0.0
 Identities = 632/798 (79%), Positives = 699/798 (87%)

Query: 1   MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
           M+F+  +  G QCLLL LLLLAA +VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV
Sbjct: 1   MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLFR+ASK   DLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+
Sbjct: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120

Query: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180
           VEV+DINDN P+FP+  + + I ESR P S F LEGASDAD+G+NS+LTY L S+EYF L
Sbjct: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180

Query: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240
           DVK N ++ K +GL+LKK+L+RE+ P H L +TA DGGKPELTGT QL +TVLDVNDNAP
Sbjct: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240

Query: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300
            FE++ Y+VR+ ENA NGT V+ +NA+D DEG N  I+YSFN+ ++A ++  F +D   G
Sbjct: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300

Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360
           +I ++GN+DFE+   Y+I ++ATDKG+PPM+ HCTVL+ I+D NDNVPE+ + SLSLPV 
Sbjct: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360

Query: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420
           ED+   TVIALISV+D DSG NGQV CSLTPHVPFKLVSTFKNYYSLVLDS LDRESVSA
Sbjct: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480
           YELVVTARDGGSPSLWATAS+SVEVAD+NDNAPAF+Q EYTVFVKENNPPGCHIFTVSAR
Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQENALVSYSLVERRVGERALSSY+SVHAESGKVYALQPLDHEELELLQFQVSARDA
Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL PRVGG GGAVSELVPRS+GAG VVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQP    AR PFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEP+LT
Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660

Query: 661 ATATVLVSLVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVLVSLVESGQAPKASS+AS GA GPEAALVDVNVYLI+AICAVSSLLVLTLLLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSAPPTEGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCP 780
           LRCSAPPTEG C   KPTLVCSSAVGSWSYSQQR+QRVCSGEG PK DLMAFSPSL PCP
Sbjct: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780

Query: 781 IMMGKAENQDLNEDHDAK 798
           I   + E QD++ D  AK
Sbjct: 781 ISRDREEKQDVDVDLSAK 798


>gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo
           sapiens]
          Length = 807

 Score = 1217 bits (3148), Expect = 0.0
 Identities = 618/790 (78%), Positives = 684/790 (86%), Gaps = 3/790 (0%)

Query: 14  LLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDRED 73
           LLL LL+LAAW+ GSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFR+ASK   D
Sbjct: 14  LLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGD 73

Query: 74  LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPLF 133
           LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+V+VRDINDNPP+F
Sbjct: 74  LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDINDNPPIF 133

Query: 134 PVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIG 193
           P  ++R++I ESR P++ FPL+GASDAD+G NS LTY+L  ++YF LD + + +    + 
Sbjct: 134 PESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLEQMSSLS 193

Query: 194 LLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFE 253
           L+L+K+LDREE   H+L LTA+DGGKPELTGTVQLL+T+LDVNDNAP F QS Y+V + E
Sbjct: 194 LVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVYKVTVLE 253

Query: 254 NADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQE 313
           NA NGT VI+LNA+D D+G NG I YSF   V   V+  F+I+ N GEI  +G LDFE++
Sbjct: 254 NAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGKLDFEEK 313

Query: 314 NLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALIS 373
            LY+I ++A DKG+ PMAGHCT+LV +LD NDN PE+ +TSLSLP+RED Q   +IALIS
Sbjct: 314 KLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPSAIIALIS 373

Query: 374 VNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433
           V+D DSG+NGQV C+LTPHVPFKLVST+KNYYSLVLDSALDRESVSAYELVVTARDGGSP
Sbjct: 374 VSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433

Query: 434 SLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYS 493
           SLWATAS+SV VAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA+DADAQENALVSYS
Sbjct: 434 SLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQENALVSYS 493

Query: 494 LVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQV 553
           LVERRVGERALSSY+SVHAESGKVYALQPLDHEELELLQFQVSARD+GVPPLGSNVTLQV
Sbjct: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLGSNVTLQV 553

Query: 554 FVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSYELQP 613
           FVLDENDNAPALL P  G  GG VSEL+PRS+GAG VVAKVRAVDADSGYNAWLSYELQ 
Sbjct: 554 FVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWLSYELQL 613

Query: 614 PASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESG 673
            A  AR PFRVGLYTGEISTTR LDE D+P HRLLVLVKDHGEPALTATATVL+SLVESG
Sbjct: 614 AAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVLLSLVESG 673

Query: 674 QAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACT 733
           QAP+ASSRAS GA GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGAC 
Sbjct: 674 QAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACA 733

Query: 734 ADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAENQDLNE 793
             KPTLVCSSA GSWSYSQQRR RVCSGEGP K DLMAFSPSL PC   +G AE     E
Sbjct: 734 PGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPC---LGSAEGTGQRE 790

Query: 794 DHDAKVSEFS 803
           +    + E S
Sbjct: 791 EDSECLKEVS 800


>gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo
           sapiens]
          Length = 950

 Score = 1216 bits (3145), Expect = 0.0
 Identities = 617/788 (78%), Positives = 683/788 (86%), Gaps = 3/788 (0%)

Query: 14  LLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDRED 73
           LLL LL+LAAW+ GSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFR+ASK   D
Sbjct: 14  LLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGD 73

Query: 74  LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPLF 133
           LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+V+VRDINDNPP+F
Sbjct: 74  LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDINDNPPIF 133

Query: 134 PVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIG 193
           P  ++R++I ESR P++ FPL+GASDAD+G NS LTY+L  ++YF LD + + +    + 
Sbjct: 134 PESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLEQMSSLS 193

Query: 194 LLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFE 253
           L+L+K+LDREE   H+L LTA+DGGKPELTGTVQLL+T+LDVNDNAP F QS Y+V + E
Sbjct: 194 LVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVYKVTVLE 253

Query: 254 NADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQE 313
           NA NGT VI+LNA+D D+G NG I YSF   V   V+  F+I+ N GEI  +G LDFE++
Sbjct: 254 NAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGKLDFEEK 313

Query: 314 NLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALIS 373
            LY+I ++A DKG+ PMAGHCT+LV +LD NDN PE+ +TSLSLP+RED Q   +IALIS
Sbjct: 314 KLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPSAIIALIS 373

Query: 374 VNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433
           V+D DSG+NGQV C+LTPHVPFKLVST+KNYYSLVLDSALDRESVSAYELVVTARDGGSP
Sbjct: 374 VSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433

Query: 434 SLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYS 493
           SLWATAS+SV VAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA+DADAQENALVSYS
Sbjct: 434 SLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQENALVSYS 493

Query: 494 LVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQV 553
           LVERRVGERALSSY+SVHAESGKVYALQPLDHEELELLQFQVSARD+GVPPLGSNVTLQV
Sbjct: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLGSNVTLQV 553

Query: 554 FVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSYELQP 613
           FVLDENDNAPALL P  G  GG VSEL+PRS+GAG VVAKVRAVDADSGYNAWLSYELQ 
Sbjct: 554 FVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWLSYELQL 613

Query: 614 PASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESG 673
            A  AR PFRVGLYTGEISTTR LDE D+P HRLLVLVKDHGEPALTATATVL+SLVESG
Sbjct: 614 AAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVLLSLVESG 673

Query: 674 QAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACT 733
           QAP+ASSRAS GA GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGAC 
Sbjct: 674 QAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACA 733

Query: 734 ADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAENQDLNE 793
             KPTLVCSSA GSWSYSQQRR RVCSGEGP K DLMAFSPSL PC   +G AE     E
Sbjct: 734 PGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPC---LGSAEGTGQRE 790

Query: 794 DHDAKVSE 801
           +    + E
Sbjct: 791 EDSECLKE 798


>gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens]
          Length = 936

 Score = 1214 bits (3140), Expect = 0.0
 Identities = 622/780 (79%), Positives = 675/780 (86%), Gaps = 1/780 (0%)

Query: 1   MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
           MV++    LG + LLL  LLLA WK GSGQLHYS+PEEAKHGTFVGRIAQDLGLELAELV
Sbjct: 1   MVYSRRGSLGSRLLLL-WLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59

Query: 61  PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLFR+ASK R DLLEVNLQNGILFVNSRIDREELC R AECSIHLEVIVDRPLQVFHV+
Sbjct: 60  PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119

Query: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180
           V V+DINDNPP F  +EQR+ I ESR+PDS FPLEGASD D+G+N+ L Y+L+ +EYF L
Sbjct: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179

Query: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240
           DVK N ++   + L+L+KSLDREE   H L + ATDGGKPELTGTVQLL+ VLD NDNAP
Sbjct: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239

Query: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300
            F++S Y VR+ ENA +GT VI+LNASD DEG N  I Y F++LV   V   F I+ NTG
Sbjct: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299

Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360
           EI + G LD+E  N Y+I IDA DK   P++GHC V+V++LD NDN PE+A+T+L LPV+
Sbjct: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359

Query: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420
           EDA   TVIALISV+D DSGANGQV CSL PHVPFKLVSTFKNYYSLVLDSALDRESVS 
Sbjct: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419

Query: 421 YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480
           YELVVTARDGGSPSLWATAS+SVEVAD+NDNAPAFAQP+YTVFVKENNPPGCHIFTVSAR
Sbjct: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479

Query: 481 DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQENALVSYSLVERRVGER LSSY+SVHAESGKVYALQPLDHEE+ELLQFQVSARDA
Sbjct: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL PRVGGTGGAVSELVPRS+GAG VVAKVRAVD D
Sbjct: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599

Query: 601 SGYNAWLSYELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQP   SAR PFRVGLYTGEISTTR LDE ++PRHRLLVLVKDHGEP LT
Sbjct: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659

Query: 661 ATATVLVSLVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVLVSLVESGQAPKASSRAS GA GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719

Query: 721 LRCSAPPTEGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCP 780
           LRCSA PTE  CT  KPTL+CSSAVGSWSYSQQRRQRVCSGE PPK DLMAFSPSL   P
Sbjct: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGP 779


>gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo
           sapiens]
          Length = 816

 Score = 1214 bits (3140), Expect = 0.0
 Identities = 622/780 (79%), Positives = 675/780 (86%), Gaps = 1/780 (0%)

Query: 1   MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
           MV++    LG + LLL  LLLA WK GSGQLHYS+PEEAKHGTFVGRIAQDLGLELAELV
Sbjct: 1   MVYSRRGSLGSRLLLL-WLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59

Query: 61  PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLFR+ASK R DLLEVNLQNGILFVNSRIDREELC R AECSIHLEVIVDRPLQVFHV+
Sbjct: 60  PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119

Query: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180
           V V+DINDNPP F  +EQR+ I ESR+PDS FPLEGASD D+G+N+ L Y+L+ +EYF L
Sbjct: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179

Query: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240
           DVK N ++   + L+L+KSLDREE   H L + ATDGGKPELTGTVQLL+ VLD NDNAP
Sbjct: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239

Query: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300
            F++S Y VR+ ENA +GT VI+LNASD DEG N  I Y F++LV   V   F I+ NTG
Sbjct: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299

Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360
           EI + G LD+E  N Y+I IDA DK   P++GHC V+V++LD NDN PE+A+T+L LPV+
Sbjct: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359

Query: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420
           EDA   TVIALISV+D DSGANGQV CSL PHVPFKLVSTFKNYYSLVLDSALDRESVS 
Sbjct: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419

Query: 421 YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480
           YELVVTARDGGSPSLWATAS+SVEVAD+NDNAPAFAQP+YTVFVKENNPPGCHIFTVSAR
Sbjct: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479

Query: 481 DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQENALVSYSLVERRVGER LSSY+SVHAESGKVYALQPLDHEE+ELLQFQVSARDA
Sbjct: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL PRVGGTGGAVSELVPRS+GAG VVAKVRAVD D
Sbjct: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599

Query: 601 SGYNAWLSYELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQP   SAR PFRVGLYTGEISTTR LDE ++PRHRLLVLVKDHGEP LT
Sbjct: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659

Query: 661 ATATVLVSLVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVLVSLVESGQAPKASSRAS GA GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719

Query: 721 LRCSAPPTEGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCP 780
           LRCSA PTE  CT  KPTL+CSSAVGSWSYSQQRRQRVCSGE PPK DLMAFSPSL   P
Sbjct: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGP 779


>gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo
           sapiens]
          Length = 798

 Score = 1212 bits (3135), Expect = 0.0
 Identities = 623/787 (79%), Positives = 680/787 (86%), Gaps = 3/787 (0%)

Query: 14  LLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDRED 73
           LLL LLLLAAW+ G+GQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFR+ASK R  
Sbjct: 14  LLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGG 73

Query: 74  LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPLF 133
           LLEVNLQNGILFVNSRIDREELC RSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPP+F
Sbjct: 74  LLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPVF 133

Query: 134 PVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIG 193
           P  ++ + I ESR  DS FPLEGASDAD+G N++LTY+LS +EYF L+   + +  K +G
Sbjct: 134 PATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKGLG 193

Query: 194 LLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFE 253
           L+L+KSLDREEAP   L LTATDGGKPELTGTVQLL+TVLD NDNAP F+++ Y+VR+ E
Sbjct: 194 LILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRLLE 253

Query: 254 NADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQE 313
           N  NGT VI+LNASD DEG NG I YSF++ ++  V   F ID  TG+I+++G +DFE+ 
Sbjct: 254 NVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFEES 313

Query: 314 NLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALIS 373
             Y+I+++  DKG  P++GHC V+V + D NDNVP++   SLSLP+REDA  GTVIALIS
Sbjct: 314 KSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTVIALIS 373

Query: 374 VNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433
           V+D D G NG V CSLT HVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP
Sbjct: 374 VSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433

Query: 434 SLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYS 493
           SLWATAS+SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQENALVSYS
Sbjct: 434 SLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS 493

Query: 494 LVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQV 553
           LVERRVGERALSSY+SVHAESGKVYALQPLDHEELELLQFQV+ARDAGVPPLGSNVTLQV
Sbjct: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGSNVTLQV 553

Query: 554 FVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSYELQP 613
           FVLDENDNAPALLAPR GGTGGAVSELVP S+G G VVAKVRAVDADSGYNAWLSYELQP
Sbjct: 554 FVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWLSYELQP 613

Query: 614 PASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESG 673
               AR PFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEPALTATATVLVSLVESG
Sbjct: 614 GTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLVSLVESG 673

Query: 674 QAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACT 733
           QAPKASSRA VGA GP+AALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA PTEGAC 
Sbjct: 674 QAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTEGACA 733

Query: 734 ADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAENQDLNE 793
             KPTLVCSSAVGSWSYSQQRR RVCSGEGPPK DLMAFSPSL   P    + +     E
Sbjct: 734 PGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSL---PDSRDREDQLQTTE 790

Query: 794 DHDAKVS 800
           +  AKVS
Sbjct: 791 ESFAKVS 797


>gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens]
          Length = 947

 Score = 1209 bits (3128), Expect = 0.0
 Identities = 617/763 (80%), Positives = 671/763 (87%)

Query: 14  LLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDRED 73
           LLL LLLLAAW+ G+GQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFR+ASK R  
Sbjct: 14  LLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGG 73

Query: 74  LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPLF 133
           LLEVNLQNGILFVNSRIDREELC RSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPP+F
Sbjct: 74  LLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPVF 133

Query: 134 PVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIG 193
           P  ++ + I ESR  DS FPLEGASDAD+G N++LTY+LS +EYF L+   + +  K +G
Sbjct: 134 PATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKGLG 193

Query: 194 LLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFE 253
           L+L+KSLDREEAP   L LTATDGGKPELTGTVQLL+TVLD NDNAP F+++ Y+VR+ E
Sbjct: 194 LILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRLLE 253

Query: 254 NADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQE 313
           N  NGT VI+LNASD DEG NG I YSF++ ++  V   F ID  TG+I+++G +DFE+ 
Sbjct: 254 NVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFEES 313

Query: 314 NLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALIS 373
             Y+I+++  DKG  P++GHC V+V + D NDNVP++   SLSLP+REDA  GTVIALIS
Sbjct: 314 KSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTVIALIS 373

Query: 374 VNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433
           V+D D G NG V CSLT HVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP
Sbjct: 374 VSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433

Query: 434 SLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYS 493
           SLWATAS+SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQENALVSYS
Sbjct: 434 SLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS 493

Query: 494 LVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQV 553
           LVERRVGERALSSY+SVHAESGKVYALQPLDHEELELLQFQV+ARDAGVPPLGSNVTLQV
Sbjct: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGSNVTLQV 553

Query: 554 FVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSYELQP 613
           FVLDENDNAPALLAPR GGTGGAVSELVP S+G G VVAKVRAVDADSGYNAWLSYELQP
Sbjct: 554 FVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWLSYELQP 613

Query: 614 PASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESG 673
               AR PFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEPALTATATVLVSLVESG
Sbjct: 614 GTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLVSLVESG 673

Query: 674 QAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACT 733
           QAPKASSRA VGA GP+AALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA PTEGAC 
Sbjct: 674 QAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTEGACA 733

Query: 734 ADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSL 776
             KPTLVCSSAVGSWSYSQQRR RVCSGEGPPK DLMAFSPSL
Sbjct: 734 PGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSL 776


>gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo
           sapiens]
          Length = 844

 Score = 1208 bits (3125), Expect = 0.0
 Identities = 628/794 (79%), Positives = 677/794 (85%), Gaps = 1/794 (0%)

Query: 9   LGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMAS 68
           LG QCLLL LLLLAAW+VGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLFR+AS
Sbjct: 8   LGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVAS 67

Query: 69  KDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDIND 128
           K   DLLEVNLQNGILFVNSRIDREELCGRS ECSIHLEVIVDRPLQVFHVDVEV+DIND
Sbjct: 68  KRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDIND 127

Query: 129 NPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDD 188
           NPP F V EQ++ I ESRL DS FPLEGASDADVG N++LTYKLS +EYF LD+    D 
Sbjct: 128 NPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDK 187

Query: 189 NKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248
           +K   L+L+K LDREE P   L LTATDGGKPE TG+V LL+ VLD NDNAP F++  YE
Sbjct: 188 DKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYE 247

Query: 249 VRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNL 308
           V+++EN  N T VIRLNASD DEG N  + YSF+SLV   +   F I+  TGEI +   +
Sbjct: 248 VKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAI 307

Query: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368
           DFE  N Y+I +D TDKG+PPM GHCTVLV +LD+NDN PE+ +TSLSLPV+EDAQ GTV
Sbjct: 308 DFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTV 367

Query: 369 IALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTAR 428
           IALISV+D DSGANGQV CSLTPHVPFKLVST+KNYYSLVLDSALDRE VSAYELVVTAR
Sbjct: 368 IALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTAR 427

Query: 429 DGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488
           DGGSP LWATAS+SVEVAD+NDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQENA
Sbjct: 428 DGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENA 487

Query: 489 LVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548
           LVSYSLVERR+GER+LSSY+SVHAESGKVYALQPLDHEELELLQFQVSARD GVPPLGSN
Sbjct: 488 LVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSN 547

Query: 549 VTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLS 608
           +TLQVFVLDENDNAPALLA   G  GGAVSELV RS+ AG VVAKVRAVDADSGYNAWLS
Sbjct: 548 LTLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLS 607

Query: 609 YELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS 668
           YELQ  A  AR PFRVGLYTGEISTTR LDE DSPR RLLVLVKDHGEP+LTATATVLVS
Sbjct: 608 YELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVS 667

Query: 669 LVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728
           LVE  QAPKASSRASVG A PE ALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA PT
Sbjct: 668 LVEGSQAPKASSRASVGVA-PEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPT 726

Query: 729 EGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAEN 788
           EGAC   KPTLVCSSAVGSWSYSQQRRQRVCSGEG PK DLMAFSPSL PCP++    E+
Sbjct: 727 EGACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCPMVDVDGED 786

Query: 789 QDLNEDHDAKVSEF 802
           Q +  DH  KV  +
Sbjct: 787 QSIGGDHSRKVGYY 800


>gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo
           sapiens]
          Length = 948

 Score = 1206 bits (3120), Expect = 0.0
 Identities = 627/790 (79%), Positives = 675/790 (85%), Gaps = 1/790 (0%)

Query: 9   LGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMAS 68
           LG QCLLL LLLLAAW+VGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLFR+AS
Sbjct: 8   LGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVAS 67

Query: 69  KDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDIND 128
           K   DLLEVNLQNGILFVNSRIDREELCGRS ECSIHLEVIVDRPLQVFHVDVEV+DIND
Sbjct: 68  KRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDIND 127

Query: 129 NPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDD 188
           NPP F V EQ++ I ESRL DS FPLEGASDADVG N++LTYKLS +EYF LD+    D 
Sbjct: 128 NPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDK 187

Query: 189 NKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248
           +K   L+L+K LDREE P   L LTATDGGKPE TG+V LL+ VLD NDNAP F++  YE
Sbjct: 188 DKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYE 247

Query: 249 VRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNL 308
           V+++EN  N T VIRLNASD DEG N  + YSF+SLV   +   F I+  TGEI +   +
Sbjct: 248 VKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAI 307

Query: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368
           DFE  N Y+I +D TDKG+PPM GHCTVLV +LD+NDN PE+ +TSLSLPV+EDAQ GTV
Sbjct: 308 DFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTV 367

Query: 369 IALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTAR 428
           IALISV+D DSGANGQV CSLTPHVPFKLVST+KNYYSLVLDSALDRE VSAYELVVTAR
Sbjct: 368 IALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTAR 427

Query: 429 DGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488
           DGGSP LWATAS+SVEVAD+NDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQENA
Sbjct: 428 DGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENA 487

Query: 489 LVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548
           LVSYSLVERR+GER+LSSY+SVHAESGKVYALQPLDHEELELLQFQVSARD GVPPLGSN
Sbjct: 488 LVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSN 547

Query: 549 VTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLS 608
           +TLQVFVLDENDNAPALLA   G  GGAVSELV RS+ AG VVAKVRAVDADSGYNAWLS
Sbjct: 548 LTLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLS 607

Query: 609 YELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS 668
           YELQ  A  AR PFRVGLYTGEISTTR LDE DSPR RLLVLVKDHGEP+LTATATVLVS
Sbjct: 608 YELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVS 667

Query: 669 LVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728
           LVE  QAPKASSRASVG A PE ALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA PT
Sbjct: 668 LVEGSQAPKASSRASVGVA-PEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPT 726

Query: 729 EGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAEN 788
           EGAC   KPTLVCSSAVGSWSYSQQRRQRVCSGEG PK DLMAFSPSL PCP++    E+
Sbjct: 727 EGACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCPMVDVDGED 786

Query: 789 QDLNEDHDAK 798
           Q +  DH  K
Sbjct: 787 QSIGGDHSRK 796


>gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 807

 Score = 1206 bits (3119), Expect = 0.0
 Identities = 619/800 (77%), Positives = 684/800 (85%)

Query: 1   MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
           MVF+    LG + LLL LLLLAAW+VGSGQLHYS+PEEAKHGTFVGR+AQDLGLELAELV
Sbjct: 1   MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60

Query: 61  PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLFR+ASK   DLLEVNLQNGILFVNSRIDREELC  SAECSIHLE+I DRPLQVFHV+
Sbjct: 61  PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120

Query: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180
           V+V+DINDNPP+F   EQ + I ESRL +S FP+EGA+DAD+G+N++LTY LS S+YF L
Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180

Query: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240
           DV+ + + +K + L L+K LDREE P  +L LTATDGGKPEL GTV+LL+TVLDVNDNAP
Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240

Query: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300
            F+Q+ Y V + E   NGT V  LNASD DEG NG + +SF+S ++  + + F +D ++G
Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300

Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360
           EI +   LD+E+   Y+I + A DKG PPM+ HC VLV++LD NDN PE+A+TSL LP+R
Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360

Query: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420
           EDA   TVIALI+V+D DSGANGQV CSL PHVPFKLVSTFKNYYSLVLDSALDRES+S 
Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420

Query: 421 YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480
           YELVVTARDGGSPSLWATA +SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR
Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQENALVSYSLVERRVGERALS+Y+SVHAESGKVYALQPLDHEELELLQFQVSARDA
Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGT GAVSELVPR +GAG VVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQP A  AR PFRVGLYTGEISTTRVLDEAD  R+RLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT 660

Query: 661 ATATVLVSLVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVLVSLVESGQAPKASSRASVG AGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSAPPTEGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCP 780
           LRCS PPTEGA    KPTLVCSSA+GSWS SQQRRQRVCS EGPPK DLMAFSP LSP  
Sbjct: 721 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL 780

Query: 781 IMMGKAENQDLNEDHDAKVS 800
               + E  + N D    VS
Sbjct: 781 NTSERNEQPEANLDLSGNVS 800


>gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score = 1204 bits (3114), Expect = 0.0
 Identities = 617/794 (77%), Positives = 682/794 (85%)

Query: 1   MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
           MVF+    LG + LLL LLLLAAW+VGSGQLHYS+PEEAKHGTFVGR+AQDLGLELAELV
Sbjct: 1   MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60

Query: 61  PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLFR+ASK   DLLEVNLQNGILFVNSRIDREELC  SAECSIHLE+I DRPLQVFHV+
Sbjct: 61  PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120

Query: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180
           V+V+DINDNPP+F   EQ + I ESRL +S FP+EGA+DAD+G+N++LTY LS S+YF L
Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180

Query: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240
           DV+ + + +K + L L+K LDREE P  +L LTATDGGKPEL GTV+LL+TVLDVNDNAP
Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240

Query: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300
            F+Q+ Y V + E   NGT V  LNASD DEG NG + +SF+S ++  + + F +D ++G
Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300

Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360
           EI +   LD+E+   Y+I + A DKG PPM+ HC VLV++LD NDN PE+A+TSL LP+R
Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360

Query: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420
           EDA   TVIALI+V+D DSGANGQV CSL PHVPFKLVSTFKNYYSLVLDSALDRES+S 
Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420

Query: 421 YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480
           YELVVTARDGGSPSLWATA +SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR
Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQENALVSYSLVERRVGERALS+Y+SVHAESGKVYALQPLDHEELELLQFQVSARDA
Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGT GAVSELVPR +GAG VVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQP A  AR PFRVGLYTGEISTTRVLDEAD  R+RLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT 660

Query: 661 ATATVLVSLVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVLVSLVESGQAPKASSRASVG AGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSAPPTEGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCP 780
           LRCS PPTEGA    KPTLVCSSA+GSWS SQQRRQRVCS EGPPK DLMAFSP LSP  
Sbjct: 721 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL 780

Query: 781 IMMGKAENQDLNED 794
               + E  + N D
Sbjct: 781 NTSERNEQPEANLD 794


>gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo
           sapiens]
          Length = 789

 Score = 1200 bits (3105), Expect = 0.0
 Identities = 614/771 (79%), Positives = 672/771 (87%)

Query: 10  GKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASK 69
           G + LLL +++LAAW+ G GQLHYSVPEEAKHG FVGRIAQDLGLELAELVPRLFR   K
Sbjct: 10  GGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCK 69

Query: 70  DREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDN 129
            R DLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIV+RPLQVFHVDVEV+DINDN
Sbjct: 70  FRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDN 129

Query: 130 PPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDN 189
           PP+FP  ++ + I ESR  DS FPLEGASDAD+G N++LTY+LS +EYF LDV  ++   
Sbjct: 130 PPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQV 189

Query: 190 KQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249
           K +GL+L+K LDREE P  +L LTATDGGKPELTGTVQLL+TVLD NDNAP F+++ Y V
Sbjct: 190 KPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTV 249

Query: 250 RIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLD 309
           ++ EN   GT VI  NASD DEG NG I YSF+S V+  +   F +D  +G I + G++D
Sbjct: 250 KLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMD 309

Query: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369
           FE+   +KI ++A DKG PP+AGHCTVLV ++D NDN P++ LTSLSLP+ EDAQ GTVI
Sbjct: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369

Query: 370 ALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429
            LISV D D G NGQV CSLTP VPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD
Sbjct: 370 TLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429

Query: 430 GGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489
           GGSPSLWATAS+SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL
Sbjct: 430 GGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNAL 489

Query: 490 VSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549
           VSYSLVE RVGERALSSY+SVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV
Sbjct: 490 VSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549

Query: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSY 609
           TLQVFVLDENDNAPALLAPRVGGTGGAV ELVPRS+GAG VVAKVRAVDADSGYNAWLSY
Sbjct: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609

Query: 610 ELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669
           ELQP A+ A  PFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEP+LTATATVLVSL
Sbjct: 610 ELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSL 669

Query: 670 VESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTE 729
           VESGQAPKASSRAS+G AGPE  LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAP +E
Sbjct: 670 VESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSE 729

Query: 730 GACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCP 780
           GAC+  KPTLVCSSAVGSWS+SQQRRQRVCSGEGPPK DLMAFSPSL   P
Sbjct: 730 GACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP 780


>gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens]
          Length = 937

 Score = 1200 bits (3105), Expect = 0.0
 Identities = 614/771 (79%), Positives = 672/771 (87%)

Query: 10  GKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASK 69
           G + LLL +++LAAW+ G GQLHYSVPEEAKHG FVGRIAQDLGLELAELVPRLFR   K
Sbjct: 10  GGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCK 69

Query: 70  DREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDN 129
            R DLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIV+RPLQVFHVDVEV+DINDN
Sbjct: 70  FRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDN 129

Query: 130 PPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDN 189
           PP+FP  ++ + I ESR  DS FPLEGASDAD+G N++LTY+LS +EYF LDV  ++   
Sbjct: 130 PPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQV 189

Query: 190 KQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249
           K +GL+L+K LDREE P  +L LTATDGGKPELTGTVQLL+TVLD NDNAP F+++ Y V
Sbjct: 190 KPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTV 249

Query: 250 RIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLD 309
           ++ EN   GT VI  NASD DEG NG I YSF+S V+  +   F +D  +G I + G++D
Sbjct: 250 KLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMD 309

Query: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369
           FE+   +KI ++A DKG PP+AGHCTVLV ++D NDN P++ LTSLSLP+ EDAQ GTVI
Sbjct: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369

Query: 370 ALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429
            LISV D D G NGQV CSLTP VPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD
Sbjct: 370 TLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429

Query: 430 GGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489
           GGSPSLWATAS+SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL
Sbjct: 430 GGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNAL 489

Query: 490 VSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549
           VSYSLVE RVGERALSSY+SVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV
Sbjct: 490 VSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549

Query: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSY 609
           TLQVFVLDENDNAPALLAPRVGGTGGAV ELVPRS+GAG VVAKVRAVDADSGYNAWLSY
Sbjct: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609

Query: 610 ELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669
           ELQP A+ A  PFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEP+LTATATVLVSL
Sbjct: 610 ELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSL 669

Query: 670 VESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTE 729
           VESGQAPKASSRAS+G AGPE  LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAP +E
Sbjct: 670 VESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSE 729

Query: 730 GACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCP 780
           GAC+  KPTLVCSSAVGSWS+SQQRRQRVCSGEGPPK DLMAFSPSL   P
Sbjct: 730 GACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP 780


>gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo
           sapiens]
          Length = 810

 Score = 1199 bits (3102), Expect = 0.0
 Identities = 622/795 (78%), Positives = 679/795 (85%), Gaps = 7/795 (0%)

Query: 9   LGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMAS 68
           LG   L L LLLL  W+VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV RLFR+AS
Sbjct: 9   LGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRVAS 68

Query: 69  KDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDIND 128
           K   DLLEVNLQNGILFVNSRIDREELCG+SAECSIHLEVIVDRPLQVFHV+VEV+DIND
Sbjct: 69  KTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDIND 128

Query: 129 NPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDD 188
           NPP+F + EQ++LI ES+  DS FPLEGASDAD+  N++LTY+LS +EYF LD   N   
Sbjct: 129 NPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNGKQ 188

Query: 189 NKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248
            K++ L+LKKSLDRE+ P  NL LTATDGGKPELTGTV+LLV VLDVNDN P F++SEY+
Sbjct: 189 IKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSEYK 248

Query: 249 VRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNL 308
           V + ENA   T V++LNA+DRDEG NG ++YS  S +       F++D+N GE+ + G L
Sbjct: 249 VSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVNGTL 307

Query: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368
           D+E+   YKI + ATDKG PPMAGHCTV V ILD NDN PE+A+TSLSLPVREDAQ  TV
Sbjct: 308 DYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPSTV 367

Query: 369 IALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTAR 428
           IALISV+D DSG NGQV CSLTPHVPFKLVSTFKNYYSLVLDSALDRE+V AYELVVTAR
Sbjct: 368 IALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVTAR 427

Query: 429 DGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488
           DGGSPSLWATA +SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA
Sbjct: 428 DGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 487

Query: 489 LVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548
           LVSYSLVERR+G+RALSSY+SVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL SN
Sbjct: 488 LVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLSSN 547

Query: 549 VTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLS 608
           VTLQVFVLDENDNAPALLA + G  GGAV++LVPRS+GAG VVAKVRAVDADSGYNAWLS
Sbjct: 548 VTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNAWLS 607

Query: 609 YELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS 668
           YELQP A  +R PFRVGLYTGEISTTR LDEADSPRHRLLVLVKDHGEPALTATATVLVS
Sbjct: 608 YELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVS 667

Query: 669 LVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728
           LVESGQAPKASSR   GAA PEAALVDVNVYLIIAIC VSSLLVLTLLLYTAL  SA PT
Sbjct: 668 LVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSATPT 727

Query: 729 EGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGK--- 785
           EGAC   KPTLVCS AVGSWSYSQQRRQRVCS EGPPK DLMAFSPSL   P+ + K   
Sbjct: 728 EGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSL---PLGLNKEEE 784

Query: 786 AENQDLNEDHDAKVS 800
            E Q+   +H  +VS
Sbjct: 785 GERQEPGSNHPGQVS 799


>gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo
           sapiens]
          Length = 824

 Score = 1198 bits (3100), Expect = 0.0
 Identities = 618/787 (78%), Positives = 680/787 (86%), Gaps = 4/787 (0%)

Query: 15  LLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDREDL 74
           LL LLLLAAW+VGSGQL YSVPEEAKHGTFVGRIAQDLGLEL ELVPRLFR+ASK   DL
Sbjct: 15  LLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDL 74

Query: 75  LEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPLFP 134
           LEVNLQNGILFVNSRIDREELCGRSAECSIH+EVIVDRPLQVFHV+VEV+DINDNPP+FP
Sbjct: 75  LEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDNPPIFP 134

Query: 135 VEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIGL 194
           +  + +   ESRL DS FPLEGASDAD+G N++L+YKLSSSE+F LD++ N + ++ + L
Sbjct: 135 MTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELSESLSL 194

Query: 195 LLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFEN 254
           +L KSLDREE    NL L ATDGGKPELTGTVQ+L+ VLDVNDN PTF QS Y+V++ EN
Sbjct: 195 VLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLEN 254

Query: 255 ADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQEN 314
             NGT V++LNASD DEG N  I YS  S V++ +   F+ID  +GEI  +G LD+E+  
Sbjct: 255 TANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAK 314

Query: 315 LYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALISV 374
            Y+I + ATDKG P M+GHC + ++++D NDN PE+++TSLSLP+ E+A  GTVIALI+V
Sbjct: 315 SYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITV 374

Query: 375 NDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434
           +D DSG NG V CSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS
Sbjct: 375 SDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434

Query: 435 LWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSL 494
           LWAT S+S+EVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQENALVSYSL
Sbjct: 435 LWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494

Query: 495 VERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVF 554
           VERRVGERALSSY+SVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLGSNVTLQVF
Sbjct: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVF 554

Query: 555 VLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSYELQPP 614
           VLDENDNAPALLAPR G   GAVSELVP S+GAG VVAKVRAVDADSGYNAWLSYELQ  
Sbjct: 555 VLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLG 614

Query: 615 ASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674
             SAR PFRVGLYTGEISTTR LDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ
Sbjct: 615 TGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674

Query: 675 APKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACTA 734
           APKASSRA VGAAG EA LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS PPTEGA   
Sbjct: 675 APKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTEGARAP 734

Query: 735 DKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAENQDLNE- 793
            KPTLVCSSAVGSWSYSQQRRQRVCSGE PPK DLMAFSPSLS  P     AE + L+E 
Sbjct: 735 GKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP---DSAEEKQLSES 791

Query: 794 DHDAKVS 800
           ++  KVS
Sbjct: 792 EYVGKVS 798


>gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens]
          Length = 948

 Score = 1197 bits (3098), Expect = 0.0
 Identities = 615/779 (78%), Positives = 675/779 (86%), Gaps = 3/779 (0%)

Query: 15  LLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDREDL 74
           LL LLLLAAW+VGSGQL YSVPEEAKHGTFVGRIAQDLGLEL ELVPRLFR+ASK   DL
Sbjct: 15  LLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDL 74

Query: 75  LEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPLFP 134
           LEVNLQNGILFVNSRIDREELCGRSAECSIH+EVIVDRPLQVFHV+VEV+DINDNPP+FP
Sbjct: 75  LEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDNPPIFP 134

Query: 135 VEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIGL 194
           +  + +   ESRL DS FPLEGASDAD+G N++L+YKLSSSE+F LD++ N + ++ + L
Sbjct: 135 MTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELSESLSL 194

Query: 195 LLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFEN 254
           +L KSLDREE    NL L ATDGGKPELTGTVQ+L+ VLDVNDN PTF QS Y+V++ EN
Sbjct: 195 VLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLEN 254

Query: 255 ADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQEN 314
             NGT V++LNASD DEG N  I YS  S V++ +   F+ID  +GEI  +G LD+E+  
Sbjct: 255 TANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAK 314

Query: 315 LYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALISV 374
            Y+I + ATDKG P M+GHC + ++++D NDN PE+++TSLSLP+ E+A  GTVIALI+V
Sbjct: 315 SYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITV 374

Query: 375 NDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434
           +D DSG NG V CSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS
Sbjct: 375 SDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434

Query: 435 LWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSL 494
           LWAT S+S+EVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQENALVSYSL
Sbjct: 435 LWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494

Query: 495 VERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVF 554
           VERRVGERALSSY+SVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLGSNVTLQVF
Sbjct: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVF 554

Query: 555 VLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSYELQPP 614
           VLDENDNAPALLAPR G   GAVSELVP S+GAG VVAKVRAVDADSGYNAWLSYELQ  
Sbjct: 555 VLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLG 614

Query: 615 ASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674
             SAR PFRVGLYTGEISTTR LDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ
Sbjct: 615 TGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674

Query: 675 APKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACTA 734
           APKASSRA VGAAG EA LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS PPTEGA   
Sbjct: 675 APKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTEGARAP 734

Query: 735 DKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAENQDLNE 793
            KPTLVCSSAVGSWSYSQQRRQRVCSGE PPK DLMAFSPSLS  P     AE + L+E
Sbjct: 735 GKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP---DSAEEKQLSE 790


>gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo
           sapiens]
          Length = 949

 Score = 1197 bits (3097), Expect = 0.0
 Identities = 619/785 (78%), Positives = 674/785 (85%), Gaps = 4/785 (0%)

Query: 9   LGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMAS 68
           LG   L L LLLL  W+VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV RLFR+AS
Sbjct: 9   LGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRVAS 68

Query: 69  KDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDIND 128
           K   DLLEVNLQNGILFVNSRIDREELCG+SAECSIHLEVIVDRPLQVFHV+VEV+DIND
Sbjct: 69  KTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDIND 128

Query: 129 NPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDD 188
           NPP+F + EQ++LI ES+  DS FPLEGASDAD+  N++LTY+LS +EYF LD   N   
Sbjct: 129 NPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNGKQ 188

Query: 189 NKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248
            K++ L+LKKSLDRE+ P  NL LTATDGGKPELTGTV+LLV VLDVNDN P F++SEY+
Sbjct: 189 IKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSEYK 248

Query: 249 VRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNL 308
           V + ENA   T V++LNA+DRDEG NG ++YS  S +       F++D+N GE+ + G L
Sbjct: 249 VSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVNGTL 307

Query: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368
           D+E+   YKI + ATDKG PPMAGHCTV V ILD NDN PE+A+TSLSLPVREDAQ  TV
Sbjct: 308 DYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPSTV 367

Query: 369 IALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTAR 428
           IALISV+D DSG NGQV CSLTPHVPFKLVSTFKNYYSLVLDSALDRE+V AYELVVTAR
Sbjct: 368 IALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVTAR 427

Query: 429 DGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488
           DGGSPSLWATA +SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA
Sbjct: 428 DGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 487

Query: 489 LVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548
           LVSYSLVERR+G+RALSSY+SVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL SN
Sbjct: 488 LVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLSSN 547

Query: 549 VTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLS 608
           VTLQVFVLDENDNAPALLA + G  GGAV++LVPRS+GAG VVAKVRAVDADSGYNAWLS
Sbjct: 548 VTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNAWLS 607

Query: 609 YELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS 668
           YELQP A  +R PFRVGLYTGEISTTR LDEADSPRHRLLVLVKDHGEPALTATATVLVS
Sbjct: 608 YELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVS 667

Query: 669 LVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728
           LVESGQAPKASSR   GAA PEAALVDVNVYLIIAIC VSSLLVLTLLLYTAL  SA PT
Sbjct: 668 LVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSATPT 727

Query: 729 EGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAEN 788
           EGAC   KPTLVCS AVGSWSYSQQRRQRVCS EGPPK DLMAFSPSL   P+ + K E 
Sbjct: 728 EGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSL---PLGLNKEEE 784

Query: 789 QDLNE 793
            +  E
Sbjct: 785 GERQE 789


>gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens]
          Length = 842

 Score = 1193 bits (3086), Expect = 0.0
 Identities = 610/788 (77%), Positives = 673/788 (85%)

Query: 12  QCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDR 71
           Q LLL LL+LA W VGSGQLHYSVPEEA+HGTFVGRIAQDLGLELAELVPRLF++ SK R
Sbjct: 12  QPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGR 71

Query: 72  EDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPP 131
            DLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEV+DINDNPP
Sbjct: 72  GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPP 131

Query: 132 LFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQ 191
           +FP  ++ + I ESR  DS FPLEGASDAD+G N++LTY+LS +EYF LDV  ++   K 
Sbjct: 132 VFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKP 191

Query: 192 IGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRI 251
           +GL+L+K LDREE P  +L LTATDGGKPELTGTVQLL+TVLD NDNAP F+++ Y V++
Sbjct: 192 LGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKL 251

Query: 252 FENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFE 311
            EN   GT VI  NASD DEG NG I YSF+S V+  +   F +D  +G I + G++DFE
Sbjct: 252 PENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFE 311

Query: 312 QENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIAL 371
           +   +KI ++A DKG PP+AGHCT+LV ++D NDN P++ + +LS+PV+EDAQ GTVIAL
Sbjct: 312 ESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIAL 371

Query: 372 ISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG 431
           ISV DLD+ ANGQV CSLTPHVPFKLVST+KNYYSLVLD ALDRESVSAYELVVTARDGG
Sbjct: 372 ISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGG 431

Query: 432 SPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVS 491
           SPSLWATA +SVEVAD+NDNAPAFAQ EYTVFVKENNPPGCHIFTVSARDADAQENALVS
Sbjct: 432 SPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVS 491

Query: 492 YSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL 551
           YSLVERR+GER+LSSY+SVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL
Sbjct: 492 YSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL 551

Query: 552 QVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSYEL 611
           QVFVLDENDNAPALL PR+ GT GAVSE+V RS+GAG VV KVRAVDADSGYNAWLSYEL
Sbjct: 552 QVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLSYEL 611

Query: 612 QPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVE 671
           QP  +SA  PFRVGLYTGEISTTR LDE D+PR RLLVLVKDHGEPALTATATVLVSLVE
Sbjct: 612 QPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVSLVE 671

Query: 672 SGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGA 731
           SGQAPK+SSRASVGA GPE  LVDVNVYLIIAICAVSSLLVLTLLLYT LRCSA PTEG 
Sbjct: 672 SGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMPTEGE 731

Query: 732 CTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAENQDL 791
           C   KPTLVCSSAVGSWSYSQQRRQRVCSGEG  K DLMAFSP LSPC     +      
Sbjct: 732 CAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCAGSTERTGEPSA 791

Query: 792 NEDHDAKV 799
           + D   KV
Sbjct: 792 SSDSTGKV 799


>gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo
           sapiens]
          Length = 950

 Score = 1192 bits (3083), Expect = 0.0
 Identities = 607/768 (79%), Positives = 668/768 (86%)

Query: 12  QCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDR 71
           Q LLL LL+LA W VGSGQLHYSVPEEA+HGTFVGRIAQDLGLELAELVPRLF++ SK R
Sbjct: 12  QPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGR 71

Query: 72  EDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPP 131
            DLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEV+DINDNPP
Sbjct: 72  GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPP 131

Query: 132 LFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQ 191
           +FP  ++ + I ESR  DS FPLEGASDAD+G N++LTY+LS +EYF LDV  ++   K 
Sbjct: 132 VFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKP 191

Query: 192 IGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRI 251
           +GL+L+K LDREE P  +L LTATDGGKPELTGTVQLL+TVLD NDNAP F+++ Y V++
Sbjct: 192 LGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKL 251

Query: 252 FENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFE 311
            EN   GT VI  NASD DEG NG I YSF+S V+  +   F +D  +G I + G++DFE
Sbjct: 252 PENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFE 311

Query: 312 QENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIAL 371
           +   +KI ++A DKG PP+AGHCT+LV ++D NDN P++ + +LS+PV+EDAQ GTVIAL
Sbjct: 312 ESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIAL 371

Query: 372 ISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG 431
           ISV DLD+ ANGQV CSLTPHVPFKLVST+KNYYSLVLD ALDRESVSAYELVVTARDGG
Sbjct: 372 ISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGG 431

Query: 432 SPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVS 491
           SPSLWATA +SVEVAD+NDNAPAFAQ EYTVFVKENNPPGCHIFTVSARDADAQENALVS
Sbjct: 432 SPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVS 491

Query: 492 YSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL 551
           YSLVERR+GER+LSSY+SVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL
Sbjct: 492 YSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL 551

Query: 552 QVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSYEL 611
           QVFVLDENDNAPALL PR+ GT GAVSE+V RS+GAG VV KVRAVDADSGYNAWLSYEL
Sbjct: 552 QVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLSYEL 611

Query: 612 QPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVE 671
           QP  +SA  PFRVGLYTGEISTTR LDE D+PR RLLVLVKDHGEPALTATATVLVSLVE
Sbjct: 612 QPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVSLVE 671

Query: 672 SGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGA 731
           SGQAPK+SSRASVGA GPE  LVDVNVYLIIAICAVSSLLVLTLLLYT LRCSA PTEG 
Sbjct: 672 SGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMPTEGE 731

Query: 732 CTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPC 779
           C   KPTLVCSSAVGSWSYSQQRRQRVCSGEG  K DLMAFSP LSPC
Sbjct: 732 CAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPC 779


>gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo
           sapiens]
          Length = 792

 Score = 1182 bits (3057), Expect = 0.0
 Identities = 612/767 (79%), Positives = 659/767 (85%)

Query: 10  GKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASK 69
           G Q LLL LLLLAAW+VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFR+ASK
Sbjct: 10  GSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69

Query: 70  DREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDN 129
              DLLEVNLQNGILFVNSRIDRE+LCGRSAECSIHLEVIVDRPLQVFHVDVEV+DINDN
Sbjct: 70  RHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDN 129

Query: 130 PPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDN 189
           PP+F   EQ+V + ES   DS FPLEGASDAD+G NS+LTY LS +E F L +K   D +
Sbjct: 130 PPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDKS 189

Query: 190 KQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249
               L+L+K LDRE+ P  NL L   DGGKPELTG+VQ+ +TVLDVNDN P F++  Y+V
Sbjct: 190 ILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYKV 249

Query: 250 RIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLD 309
            + EN  N T VI+LNASD DEG NG ISY    ++       FSI+ +TGEI I G LD
Sbjct: 250 VLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGELD 309

Query: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369
           FE+ N Y+I ++A DKG P MAGH  VLV +LD NDNVPE+ +TSLSLPV+EDAQ GTVI
Sbjct: 310 FEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTVI 369

Query: 370 ALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429
           ALISV+D DSGANGQV CSLTPHVPFKLVST+KNYYSLVLDSALDRESVSAYELVVTARD
Sbjct: 370 ALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARD 429

Query: 430 GGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489
           GGSPSLWATA +SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL
Sbjct: 430 GGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNAL 489

Query: 490 VSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549
           VSYSLVERRVGE ALSSY+SVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV
Sbjct: 490 VSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549

Query: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSY 609
           TLQVFVLDENDNAPALLA   G  GGAVSELVPRS+GAG VVAKVRAVDADSGYNAWLSY
Sbjct: 550 TLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609

Query: 610 ELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669
           ELQP A  A  PF VGLYTGEISTTR+LDEAD+PRHRLLVLVKDHGEPALT+TATVLVSL
Sbjct: 610 ELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLVSL 669

Query: 670 VESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTE 729
           VE+GQAPK SSRASVGA  PEAALVD+NVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 
Sbjct: 670 VENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPPTV 729

Query: 730 GACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSL 776
             C   KPTLVCSSAVGSWSYSQQRRQRVCS E PPK DLMAFSPSL
Sbjct: 730 SRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776


>gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo
           sapiens]
          Length = 941

 Score = 1182 bits (3057), Expect = 0.0
 Identities = 612/767 (79%), Positives = 659/767 (85%)

Query: 10  GKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASK 69
           G Q LLL LLLLAAW+VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFR+ASK
Sbjct: 10  GSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69

Query: 70  DREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDN 129
              DLLEVNLQNGILFVNSRIDRE+LCGRSAECSIHLEVIVDRPLQVFHVDVEV+DINDN
Sbjct: 70  RHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDN 129

Query: 130 PPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDN 189
           PP+F   EQ+V + ES   DS FPLEGASDAD+G NS+LTY LS +E F L +K   D +
Sbjct: 130 PPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDKS 189

Query: 190 KQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249
               L+L+K LDRE+ P  NL L   DGGKPELTG+VQ+ +TVLDVNDN P F++  Y+V
Sbjct: 190 ILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYKV 249

Query: 250 RIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLD 309
            + EN  N T VI+LNASD DEG NG ISY    ++       FSI+ +TGEI I G LD
Sbjct: 250 VLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGELD 309

Query: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369
           FE+ N Y+I ++A DKG P MAGH  VLV +LD NDNVPE+ +TSLSLPV+EDAQ GTVI
Sbjct: 310 FEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTVI 369

Query: 370 ALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429
           ALISV+D DSGANGQV CSLTPHVPFKLVST+KNYYSLVLDSALDRESVSAYELVVTARD
Sbjct: 370 ALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARD 429

Query: 430 GGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489
           GGSPSLWATA +SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL
Sbjct: 430 GGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNAL 489

Query: 490 VSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549
           VSYSLVERRVGE ALSSY+SVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV
Sbjct: 490 VSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549

Query: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSY 609
           TLQVFVLDENDNAPALLA   G  GGAVSELVPRS+GAG VVAKVRAVDADSGYNAWLSY
Sbjct: 550 TLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609

Query: 610 ELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669
           ELQP A  A  PF VGLYTGEISTTR+LDEAD+PRHRLLVLVKDHGEPALT+TATVLVSL
Sbjct: 610 ELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLVSL 669

Query: 670 VESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTE 729
           VE+GQAPK SSRASVGA  PEAALVD+NVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 
Sbjct: 670 VENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPPTV 729

Query: 730 GACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSL 776
             C   KPTLVCSSAVGSWSYSQQRRQRVCS E PPK DLMAFSPSL
Sbjct: 730 SRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776


>gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo
           sapiens]
          Length = 686

 Score = 1050 bits (2716), Expect = 0.0
 Identities = 534/534 (100%), Positives = 534/534 (100%)

Query: 1   MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
           MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV
Sbjct: 1   MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD
Sbjct: 61  PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120

Query: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180
           VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL
Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180

Query: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240
           DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP
Sbjct: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240

Query: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300
           TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG
Sbjct: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300

Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360
           EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR
Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360

Query: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420
           EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA
Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480
           YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR
Sbjct: 421 YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQ 534
           DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQ
Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQ 534



 Score =  162 bits (411), Expect = 9e-40
 Identities = 115/386 (29%), Positives = 186/386 (48%), Gaps = 16/386 (4%)

Query: 230 VTVLDVNDNAPTFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSL-VAAM 288
           V V D+NDN P F   E  V I+E+    +      ASD D G+N  ++Y  +S     +
Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180

Query: 289 VIDHFSIDRNTGEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVP 348
            +   S D     ++++ +LD E+   + + + ATD G P + G   +LV +LD NDN P
Sbjct: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240

Query: 349 EIALTSLSLPVREDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTF---KNYY 405
               +   + + E+A  GT +  ++ +D D GANG ++ S    V   ++  F   +N  
Sbjct: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300

Query: 406 SLVLDSALDRESVSAYELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVK 465
            +V+   LD E  + Y++++ A D G P +    ++ V + D NDN P  A    ++ V+
Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360

Query: 466 ENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDH 525
           E+   G  I  +S  D D+  N  V+ SL    V  + +S++ + ++    +     LD 
Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPH-VPFKLVSTFKNYYS----LVLDSALDR 415

Query: 526 EELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSL 585
           E +   +  V+ARD G P L +  +L V V D NDNAPA   P         +  V  + 
Sbjct: 416 ESVSAYELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPE-------YTVFVKENN 468

Query: 586 GAGQVVAKVRAVDADSGYNAWLSYEL 611
             G  +  V A DAD+  NA +SY L
Sbjct: 469 PPGCHIFTVSARDADAQENALVSYSL 494



 Score =  143 bits (360), Expect = 7e-34
 Identities = 104/341 (30%), Positives = 156/341 (45%), Gaps = 21/341 (6%)

Query: 338 VRILDKNDNVPEIALTSLSLPVREDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPF-- 395
           V + D NDN P   +    + + E     +V  L   +D D G+N  +   L+    F  
Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180

Query: 396 --KLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWATASLSVEVADMNDNAP 453
             K+ S       L+L  +LDRE   A+ L +TA DGG P L  T  L V V D+NDNAP
Sbjct: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240

Query: 454 AFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERALSSYISVHAE 513
            F Q EY V + EN   G  +  ++A D D   N  +SYS     +    +  + S+   
Sbjct: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSF--NSLVAAMVIDHFSIDRN 298

Query: 514 SGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRVGGT 573
           +G++     LD E+  L +  + A D G PP+  + T+ V +LD+NDN P +        
Sbjct: 299 TGEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALT----- 353

Query: 574 GGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSYELQPPASSARFPFR-VGLYTGEIS 632
             ++S  V      G V+A +   D DSG N  ++  L P       PF+ V  +    S
Sbjct: 354 --SLSLPVREDAQFGTVIALISVNDLDSGANGQVNCSLTP-----HVPFKLVSTFKNYYS 406

Query: 633 TT--RVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVE 671
                 LD      + L+V  +D G P+L ATA++ V + +
Sbjct: 407 LVLDSALDRESVSAYELVVTARDGGSPSLWATASLSVEVAD 447


>gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo
           sapiens]
          Length = 685

 Score =  795 bits (2054), Expect = 0.0
 Identities = 408/526 (77%), Positives = 449/526 (85%)

Query: 9   LGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMAS 68
           LG QCLLL LLLLAAW+VGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLFR+AS
Sbjct: 8   LGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVAS 67

Query: 69  KDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDIND 128
           K   DLLEVNLQNGILFVNSRIDREELCGRS ECSIHLEVIVDRPLQVFHVDVEV+DIND
Sbjct: 68  KRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDIND 127

Query: 129 NPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDD 188
           NPP F V EQ++ I ESRL DS FPLEGASDADVG N++LTYKLS +EYF LD+    D 
Sbjct: 128 NPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDK 187

Query: 189 NKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248
           +K   L+L+K LDREE P   L LTATDGGKPE TG+V LL+ VLD NDNAP F++  YE
Sbjct: 188 DKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYE 247

Query: 249 VRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNL 308
           V+++EN  N T VIRLNASD DEG N  + YSF+SLV   +   F I+  TGEI +   +
Sbjct: 248 VKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAI 307

Query: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368
           DFE  N Y+I +D TDKG+PPM GHCTVLV +LD+NDN PE+ +TSLSLPV+EDAQ GTV
Sbjct: 308 DFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTV 367

Query: 369 IALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTAR 428
           IALISV+D DSGANGQV CSLTPHVPFKLVST+KNYYSLVLDSALDRE VSAYELVVTAR
Sbjct: 368 IALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTAR 427

Query: 429 DGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488
           DGGSP LWATAS+SVEVAD+NDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQENA
Sbjct: 428 DGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENA 487

Query: 489 LVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQ 534
           LVSYSLVERR+GER+LSSY+SVHAESGKVYALQPLDHEELELLQFQ
Sbjct: 488 LVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQ 533



 Score =  144 bits (364), Expect = 2e-34
 Identities = 114/387 (29%), Positives = 183/387 (47%), Gaps = 18/387 (4%)

Query: 230 VTVLDVNDNAPTFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSF--NSLVAA 287
           V V D+NDN P F  +E ++ I E+    +      ASD D G N  ++Y    N     
Sbjct: 120 VEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVL 179

Query: 288 MVIDHFSIDRNTGEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNV 347
            +I+    D+    +V+R  LD E+    K+L+ ATD G P   G  ++L+ +LD NDN 
Sbjct: 180 DIINKKDKDKFP-VLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNA 238

Query: 348 PEIALTSLSLPVREDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTF---KNY 404
           P        + + E+    T++  ++ +D D G N ++  S +  VP  +   F   +  
Sbjct: 239 PIFDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERT 298

Query: 405 YSLVLDSALDRESVSAYELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFV 464
             + ++ A+D E  + YE+ V   D G+P +    ++ VE+ D NDN+P       ++ V
Sbjct: 299 GEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPV 358

Query: 465 KENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLD 524
           KE+   G  I  +S  D D+  N  V+ SL    V  + +S+Y + ++    +     LD
Sbjct: 359 KEDAQVGTVIALISVSDHDSGANGQVTCSLTPH-VPFKLVSTYKNYYS----LVLDSALD 413

Query: 525 HEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRS 584
            E +   +  V+ARD G PPL +  ++ V V D NDNAPA             +  V  +
Sbjct: 414 RERVSAYELVVTARDGGSPPLWATASVSVEVADVNDNAPAF-------AQSEYTVFVKEN 466

Query: 585 LGAGQVVAKVRAVDADSGYNAWLSYEL 611
              G  +  V A DAD+  NA +SY L
Sbjct: 467 NPPGCHIFTVSAWDADAQENALVSYSL 493



 Score =  132 bits (332), Expect = 1e-30
 Identities = 101/341 (29%), Positives = 153/341 (44%), Gaps = 21/341 (6%)

Query: 338 VRILDKNDNVPEIALTSLSLPVREDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKL 397
           V + D NDN P  ++T   L + E     +   L   +D D G N  +   L+P+  F L
Sbjct: 120 VEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVL 179

Query: 398 VSTFKN----YYSLVLDSALDRESVSAYELVVTARDGGSPSLWATASLSVEVADMNDNAP 453
               K     +  LVL   LDRE     +L++TA DGG P    + SL + V D NDNAP
Sbjct: 180 DIINKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAP 239

Query: 454 AFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERALSSYISVHAE 513
            F +P Y V + EN      +  ++A D+D   N  + YS     +    +     ++  
Sbjct: 240 IFDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSS--LVPPTIRRKFWINER 297

Query: 514 SGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRVGGT 573
           +G++     +D E+    +  V   D G PP+  + T+ V +LDENDN+P ++       
Sbjct: 298 TGEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVT----- 352

Query: 574 GGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSYELQPPASSARFPFR-VGLYTGEIS 632
             ++S  V      G V+A +   D DSG N  ++  L P       PF+ V  Y    S
Sbjct: 353 --SLSLPVKEDAQVGTVIALISVSDHDSGANGQVTCSLTP-----HVPFKLVSTYKNYYS 405

Query: 633 TT--RVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVE 671
                 LD      + L+V  +D G P L ATA+V V + +
Sbjct: 406 LVLDSALDRERVSAYELVVTARDGGSPPLWATASVSVEVAD 446



 Score = 91.3 bits (225), Expect = 3e-18
 Identities = 84/273 (30%), Positives = 118/273 (43%), Gaps = 21/273 (7%)

Query: 441 LSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVG 500
           + VEV D+NDN P F+  E  + + E+           A DAD  ENAL++Y L      
Sbjct: 118 VDVEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYF 177

Query: 501 ERALSSYISVHAESGKVYALQPL-DHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDEN 559
              L        +   V  L+ L D EE   L+  ++A D G P    +V+L + VLD N
Sbjct: 178 --VLDIINKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDAN 235

Query: 560 DNAPALLAPRVGGTGGAVSELVPRSLGAGQ-VVAKVRAVDADSGYNAWLSYE---LQPPA 615
           DNAP    P        V E+        Q +V ++ A D+D G N  + Y    L PP 
Sbjct: 236 DNAPIFDRP--------VYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPP- 286

Query: 616 SSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQA 675
            + R  F +   TGEI     +D  DS  + + V V D G P +    TVLV L++    
Sbjct: 287 -TIRRKFWINERTGEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDN 345

Query: 676 PKASSRASVGAAGPEAALVDVNVYLIIAICAVS 708
                  S+     E    D  V  +IA+ +VS
Sbjct: 346 SPEVIVTSLSLPVKE----DAQVGTVIALISVS 374


>gi|14165402 protocadherin alpha 1 isoform 3 precursor [Homo
           sapiens]
          Length = 686

 Score =  780 bits (2014), Expect = 0.0
 Identities = 392/534 (73%), Positives = 452/534 (84%)

Query: 1   MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
           MVF+    LG + LLL LLLLAAW+VGSGQLHYS+PEEAKHGTFVGR+AQDLGLELAELV
Sbjct: 1   MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60

Query: 61  PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLFR+ASK   DLLEVNLQNGILFVNSRIDREELC  SAECSIHLE+I DRPLQVFHV+
Sbjct: 61  PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120

Query: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180
           V+V+DINDNPP+F   EQ + I ESRL +S FP+EGA+DAD+G+N++LTY LS S+YF L
Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180

Query: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240
           DV+ + + +K + L L+K LDREE P  +L LTATDGGKPEL GTV+LL+TVLDVNDNAP
Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240

Query: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300
            F+Q+ Y V + E   NGT V  LNASD DEG NG + +SF+S ++  + + F +D ++G
Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300

Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360
           EI +   LD+E+   Y+I + A DKG PPM+ HC VLV++LD NDN PE+A+TSL LP+R
Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360

Query: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420
           EDA   TVIALI+V+D DSGANGQV CSL PHVPFKLVSTFKNYYSLVLDSALDRES+S 
Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420

Query: 421 YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480
           YELVVTARDGGSPSLWATA +SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR
Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQ 534
           DADAQENALVSYSLVERRVGERALS+Y+SVHAESGKVYALQPLDHEELELLQFQ
Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQ 534



 Score =  150 bits (379), Expect = 5e-36
 Identities = 118/392 (30%), Positives = 183/392 (46%), Gaps = 28/392 (7%)

Query: 230 VTVLDVNDNAPTFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMV 289
           V V D+NDN P F   E  + I E+    +      A+D D GAN  ++Y+ +       
Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPS----- 175

Query: 290 IDHFSIDRNTGE-------IVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILD 342
            D+FS+D    +       + +R  LD E+     +L+ ATD G P + G   +L+ +LD
Sbjct: 176 -DYFSLDVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLD 234

Query: 343 KNDNVPEIALTSLSLPVREDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFK 402
            NDN P        + + E    GT++  ++ +D D G NG+V  S    +   +   FK
Sbjct: 235 VNDNAPLFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFK 294

Query: 403 NYYS---LVLDSALDRESVSAYELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPE 459
              S   + L   LD E   +YE+ V A D GSP +     + V+V D+NDNAP  A   
Sbjct: 295 VDSSSGEIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTS 354

Query: 460 YTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERALSSYISVHAESGKVYA 519
             + ++E+ P    I  ++  D D+  N  V+ SL+   V  + +S++ + ++    +  
Sbjct: 355 LYLPIREDAPLSTVIALITVSDRDSGANGQVTCSLMPH-VPFKLVSTFKNYYS----LVL 409

Query: 520 LQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSE 579
              LD E L + +  V+ARD G P L +   + V V D NDNAPA   P         + 
Sbjct: 410 DSALDRESLSVYELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPE-------YTV 462

Query: 580 LVPRSLGAGQVVAKVRAVDADSGYNAWLSYEL 611
            V  +   G  +  V A DAD+  NA +SY L
Sbjct: 463 FVKENNPPGCHIFTVSARDADAQENALVSYSL 494



 Score =  136 bits (343), Expect = 7e-32
 Identities = 110/349 (31%), Positives = 157/349 (44%), Gaps = 33/349 (9%)

Query: 336 VLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPF 395
           V V++ D NDN P        + + E     +   +    D D GAN  +  +L+P   F
Sbjct: 119 VEVKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYF 178

Query: 396 KLVSTFKNYYS----LVLDSALDRESVSAYELVVTARDGGSPSLWATASLSVEVADMNDN 451
            L     +  S    L L   LDRE      L++TA DGG P L  T  L + V D+NDN
Sbjct: 179 SLDVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDN 238

Query: 452 APAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSL---VERRVGERALSSYI 508
           AP F Q  Y V + E    G  + T++A DAD   N  V +S    + R + E+      
Sbjct: 239 APLFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEK-----F 293

Query: 509 SVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAP 568
            V + SG++  +  LD+EE +  + QV A D G PP+ ++  + V VLD NDNAP L   
Sbjct: 294 KVDSSSGEIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPEL--- 350

Query: 569 RVGGTGGAVSEL---VPRSLGAGQVVAKVRAVDADSGYNAWLSYELQPPASSARFPFR-V 624
                  AV+ L   +        V+A +   D DSG N  ++  L P       PF+ V
Sbjct: 351 -------AVTSLYLPIREDAPLSTVIALITVSDRDSGANGQVTCSLMP-----HVPFKLV 398

Query: 625 GLYTGEISTT--RVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVE 671
             +    S      LD      + L+V  +D G P+L ATA V V + +
Sbjct: 399 STFKNYYSLVLDSALDRESLSVYELVVTARDGGSPSLWATARVSVEVAD 447


>gi|14277677 protocadherin gamma subfamily C, 3 isoform 2 precursor
           [Homo sapiens]
          Length = 863

 Score =  601 bits (1549), Expect = e-171
 Identities = 317/698 (45%), Positives = 446/698 (63%), Gaps = 8/698 (1%)

Query: 18  LLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDREDLLEV 77
           LLLL A    S  +HY +PEE + G  VG +  +LGL+L  L  R FR+ S       EV
Sbjct: 20  LLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFEV 79

Query: 78  NLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPLFPVEE 137
           N + G +FVN R+DREELCG    C++ LE++V+ PL++F V+V ++DINDN P FP +E
Sbjct: 80  NRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQE 139

Query: 138 QRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIGLLLK 197
            ++ I E+  P + FPLE A D DVGSNS+ TY+LS +EYF L V+   D  K   L+L+
Sbjct: 140 MKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVLE 199

Query: 198 KSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFENADN 257
           ++LDRE  P+  L LTA DGG P L+ ++ + + VLD NDNAP F QS Y  R+ E+A +
Sbjct: 200 RALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAPS 259

Query: 258 GTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQENLYK 317
           GT V+++ A+D DEG NG I YSF S   A V   F++D  TG + I+G LDFE   L++
Sbjct: 260 GTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLHE 319

Query: 318 ILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALISVNDL 377
           I I A DKG  P   HC VLV ++D NDN PEI +TS+  PV EDA  GTVIAL+SV DL
Sbjct: 320 IYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTDL 379

Query: 378 DSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWA 437
           D+G NG V C + P +PF L S+ KNY++L   + LDRE+V  Y L +TARD G+PSL A
Sbjct: 380 DAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLSA 439

Query: 438 TASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVER 497
              + V+V+D+NDN P  +Q  Y V+++ENN PG  I  +S  D DA +NA +S+ L+E+
Sbjct: 440 LTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLEQ 499

Query: 498 RVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLD 557
                 +  Y +++ ++G V +L PLD+E+    +      D G P L +N+++ +FV D
Sbjct: 500 GAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVTD 559

Query: 558 ENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSYELQPPASS 617
            NDNAP +L PR GG+     E++PR   AG +V++V   DAD+G+NAWLSY L    S 
Sbjct: 560 RNDNAPQVLYPRPGGSS---VEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLL--GSP 614

Query: 618 ARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQAPK 677
            +  F +GL+TG+IST R + + DSPR  L VL+KD+GEP+L+ TAT+ VS+ E   +P+
Sbjct: 615 NQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTE--DSPE 672

Query: 678 ASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTL 715
           A +    G+A P     ++  YL++++  VS   V+T+
Sbjct: 673 ARAEFPSGSA-PREQKKNLTFYLLLSLILVSVGFVVTV 709


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.133    0.381 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,777,437
Number of Sequences: 37866
Number of extensions: 1395680
Number of successful extensions: 10143
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 189
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 2933
Number of HSP's gapped (non-prelim): 706
length of query: 803
length of database: 18,247,518
effective HSP length: 110
effective length of query: 693
effective length of database: 14,082,258
effective search space: 9759004794
effective search space used: 9759004794
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.