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Search of human proteins with 14165381
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo
sapiens]
(844 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo sap... 1659 0.0
gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo sapi... 1561 0.0
gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo sapi... 1208 0.0
gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens] 1206 0.0
gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo sap... 1203 0.0
gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo sapi... 1203 0.0
gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo sapi... 1203 0.0
gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens] 1200 0.0
gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo sapi... 1194 0.0
gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens] 1191 0.0
gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo sap... 1189 0.0
gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens] 1188 0.0
gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo sapi... 1187 0.0
gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo sapi... 1184 0.0
gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens] 1184 0.0
gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo sapi... 1180 0.0
gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo sapi... 1178 0.0
gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens] 1178 0.0
gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo sap... 1175 0.0
gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo sapi... 1175 0.0
gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens] 1174 0.0
gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapi... 1174 0.0
gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo sapi... 1169 0.0
gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens] 1167 0.0
gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo sapi... 1158 0.0
gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens] 1158 0.0
gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo sap... 1053 0.0
gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo sapi... 795 0.0
gi|14165402 protocadherin alpha 1 isoform 3 precursor [Homo sapi... 775 0.0
gi|14277677 protocadherin gamma subfamily C, 3 isoform 2 precurs... 595 e-170
>gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo
sapiens]
Length = 844
Score = 1659 bits (4296), Expect = 0.0
Identities = 844/844 (100%), Positives = 844/844 (100%)
Query: 1 MVSRCSCLGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQ 60
MVSRCSCLGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQ
Sbjct: 1 MVSRCSCLGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQ 60
Query: 61 RLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDV 120
RLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDV
Sbjct: 61 RLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDV 120
Query: 121 EVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLD 180
EVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLD
Sbjct: 121 EVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLD 180
Query: 181 IINKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPI 240
IINKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPI
Sbjct: 181 IINKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPI 240
Query: 241 FDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGE 300
FDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGE
Sbjct: 241 FDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGE 300
Query: 301 IKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKE 360
IKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKE
Sbjct: 301 IKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKE 360
Query: 361 DAQVGTVIALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAY 420
DAQVGTVIALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAY
Sbjct: 361 DAQVGTVIALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAY 420
Query: 421 ELVVTARDGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWD 480
ELVVTARDGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWD
Sbjct: 421 ELVVTARDGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWD 480
Query: 481 ADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGG 540
ADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGG
Sbjct: 481 ADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGG 540
Query: 541 VPPLGSNLTLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADS 600
VPPLGSNLTLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADS
Sbjct: 541 VPPLGSNLTLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADS 600
Query: 601 GYNAWLSYELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTA 660
GYNAWLSYELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTA
Sbjct: 601 GYNAWLSYELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTA 660
Query: 661 TATVLVSLVEGSQAPKASSRASVGVAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALR 720
TATVLVSLVEGSQAPKASSRASVGVAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALR
Sbjct: 661 TATVLVSLVEGSQAPKASSRASVGVAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALR 720
Query: 721 CSAAPTEGACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCPMV 780
CSAAPTEGACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCPMV
Sbjct: 721 CSAAPTEGACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCPMV 780
Query: 781 DVDGEDQSIGGDHSRKVGYYVFIFLLCFMNNIFSYRIFSNMYQNISFLSTFHLCLNISSD 840
DVDGEDQSIGGDHSRKVGYYVFIFLLCFMNNIFSYRIFSNMYQNISFLSTFHLCLNISSD
Sbjct: 781 DVDGEDQSIGGDHSRKVGYYVFIFLLCFMNNIFSYRIFSNMYQNISFLSTFHLCLNISSD 840
Query: 841 TFVI 844
TFVI
Sbjct: 841 TFVI 844
>gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo
sapiens]
Length = 948
Score = 1561 bits (4042), Expect = 0.0
Identities = 796/796 (100%), Positives = 796/796 (100%)
Query: 1 MVSRCSCLGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQ 60
MVSRCSCLGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQ
Sbjct: 1 MVSRCSCLGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQ 60
Query: 61 RLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDV 120
RLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDV
Sbjct: 61 RLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDV 120
Query: 121 EVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLD 180
EVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLD
Sbjct: 121 EVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLD 180
Query: 181 IINKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPI 240
IINKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPI
Sbjct: 181 IINKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPI 240
Query: 241 FDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGE 300
FDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGE
Sbjct: 241 FDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGE 300
Query: 301 IKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKE 360
IKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKE
Sbjct: 301 IKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKE 360
Query: 361 DAQVGTVIALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAY 420
DAQVGTVIALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAY
Sbjct: 361 DAQVGTVIALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAY 420
Query: 421 ELVVTARDGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWD 480
ELVVTARDGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWD
Sbjct: 421 ELVVTARDGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWD 480
Query: 481 ADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGG 540
ADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGG
Sbjct: 481 ADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGG 540
Query: 541 VPPLGSNLTLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADS 600
VPPLGSNLTLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADS
Sbjct: 541 VPPLGSNLTLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADS 600
Query: 601 GYNAWLSYELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTA 660
GYNAWLSYELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTA
Sbjct: 601 GYNAWLSYELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTA 660
Query: 661 TATVLVSLVEGSQAPKASSRASVGVAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALR 720
TATVLVSLVEGSQAPKASSRASVGVAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALR
Sbjct: 661 TATVLVSLVEGSQAPKASSRASVGVAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALR 720
Query: 721 CSAAPTEGACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCPMV 780
CSAAPTEGACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCPMV
Sbjct: 721 CSAAPTEGACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCPMV 780
Query: 781 DVDGEDQSIGGDHSRK 796
DVDGEDQSIGGDHSRK
Sbjct: 781 DVDGEDQSIGGDHSRK 796
>gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo
sapiens]
Length = 803
Score = 1208 bits (3125), Expect = 0.0
Identities = 628/794 (79%), Positives = 677/794 (85%), Gaps = 1/794 (0%)
Query: 8 LGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVAS 67
LG QCLLL LLLLAAW+VGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLFR+AS
Sbjct: 9 LGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMAS 68
Query: 68 KRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDIND 127
K DLLEVNLQNGILFVNSRIDREELCGRS ECSIHLEVIVDRPLQVFHVDVEV+DIND
Sbjct: 69 KDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDIND 128
Query: 128 NPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDK 187
NPP F V EQ++ I ESRL DS FPLEGASDADVG N++LTYKLS +EYF LD+ D
Sbjct: 129 NPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDD 188
Query: 188 DKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYE 247
+K L+L+K LDREE P L LTATDGGKPE TG+V LL+ VLD NDNAP F++ YE
Sbjct: 189 NKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248
Query: 248 VKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAI 307
V+++EN N T VIRLNASD DEG N + YSF+SLV + F I+ TGEI + +
Sbjct: 249 VRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNL 308
Query: 308 DFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTV 367
DFE N Y+I +D TDKG+PPM GHCTVLV +LD+NDN PE+ +TSLSLPV+EDAQ GTV
Sbjct: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368
Query: 368 IALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTAR 427
IALISV+D DSGANGQV CSLTPHVPFKLVST+KNYYSLVLDSALDRE VSAYELVVTAR
Sbjct: 369 IALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTAR 428
Query: 428 DGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENA 487
DGGSP LWATAS+SVEVAD+NDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQENA
Sbjct: 429 DGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488
Query: 488 LVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSN 547
LVSYSLVERR+GER+LSSY+SVHAESGKVYALQPLDHEELELLQFQVSARD GVPPLGSN
Sbjct: 489 LVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548
Query: 548 LTLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLS 607
+TLQVFVLDENDNAPALLA G GGAVSELV RS+ AG VVAKVRAVDADSGYNAWLS
Sbjct: 549 VTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLS 608
Query: 608 YELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVS 667
YELQ A AR PFRVGLYTGEISTTR LDE DSPR RLLVLVKDHGEP+LTATATVLVS
Sbjct: 609 YELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS 668
Query: 668 LVEGSQAPKASSRASVGVA-PEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPT 726
LVE QAPKASSRASVG A PE ALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA PT
Sbjct: 669 LVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728
Query: 727 EGACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCPMVDVDGED 786
EGAC KPTLVCSSAVGSWSYSQQRRQRVCSGEG PK DLMAFSPSL PCP++ E+
Sbjct: 729 EGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAEN 788
Query: 787 QSIGGDHSRKVGYY 800
Q + DH KV +
Sbjct: 789 QDLNEDHDAKVSEF 802
>gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens]
Length = 950
Score = 1206 bits (3120), Expect = 0.0
Identities = 627/790 (79%), Positives = 675/790 (85%), Gaps = 1/790 (0%)
Query: 8 LGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVAS 67
LG QCLLL LLLLAAW+VGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLFR+AS
Sbjct: 9 LGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMAS 68
Query: 68 KRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDIND 127
K DLLEVNLQNGILFVNSRIDREELCGRS ECSIHLEVIVDRPLQVFHVDVEV+DIND
Sbjct: 69 KDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDIND 128
Query: 128 NPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDK 187
NPP F V EQ++ I ESRL DS FPLEGASDADVG N++LTYKLS +EYF LD+ D
Sbjct: 129 NPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDD 188
Query: 188 DKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYE 247
+K L+L+K LDREE P L LTATDGGKPE TG+V LL+ VLD NDNAP F++ YE
Sbjct: 189 NKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248
Query: 248 VKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAI 307
V+++EN N T VIRLNASD DEG N + YSF+SLV + F I+ TGEI + +
Sbjct: 249 VRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNL 308
Query: 308 DFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTV 367
DFE N Y+I +D TDKG+PPM GHCTVLV +LD+NDN PE+ +TSLSLPV+EDAQ GTV
Sbjct: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368
Query: 368 IALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTAR 427
IALISV+D DSGANGQV CSLTPHVPFKLVST+KNYYSLVLDSALDRE VSAYELVVTAR
Sbjct: 369 IALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTAR 428
Query: 428 DGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENA 487
DGGSP LWATAS+SVEVAD+NDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQENA
Sbjct: 429 DGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488
Query: 488 LVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSN 547
LVSYSLVERR+GER+LSSY+SVHAESGKVYALQPLDHEELELLQFQVSARD GVPPLGSN
Sbjct: 489 LVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548
Query: 548 LTLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLS 607
+TLQVFVLDENDNAPALLA G GGAVSELV RS+ AG VVAKVRAVDADSGYNAWLS
Sbjct: 549 VTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLS 608
Query: 608 YELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVS 667
YELQ A AR PFRVGLYTGEISTTR LDE DSPR RLLVLVKDHGEP+LTATATVLVS
Sbjct: 609 YELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS 668
Query: 668 LVEGSQAPKASSRASVGVA-PEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPT 726
LVE QAPKASSRASVG A PE ALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA PT
Sbjct: 669 LVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728
Query: 727 EGACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCPMVDVDGED 786
EGAC KPTLVCSSAVGSWSYSQQRRQRVCSGEG PK DLMAFSPSL PCP++ E+
Sbjct: 729 EGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAEN 788
Query: 787 QSIGGDHSRK 796
Q + DH K
Sbjct: 789 QDLNEDHDAK 798
>gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo
sapiens]
Length = 792
Score = 1203 bits (3113), Expect = 0.0
Identities = 626/767 (81%), Positives = 663/767 (86%), Gaps = 1/767 (0%)
Query: 9 GVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASK 68
G Q LLLSLLLLAAWEVGSGQLHYSVYEEA+HGTFVGRIAQDLGLELAELV RLFRVASK
Sbjct: 10 GSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69
Query: 69 RHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDN 128
RHGDLLEVNLQNGILFVNSRIDRE+LCGRS ECSIHLEVIVDRPLQVFHVDVEVKDINDN
Sbjct: 70 RHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDN 129
Query: 129 PPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKD 188
PP F EQK+ + ES LDS FPLEGASDAD+G N+LLTY LS NE F L I KKDK
Sbjct: 130 PPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDKS 189
Query: 189 KFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEV 248
P LVLRKLLDRE+ P+L LLL DGGKPE TGSV + I VLD NDN P FD+P Y+V
Sbjct: 190 ILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYKV 249
Query: 249 KMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAID 308
+ EN N T VI+LNASD DEG+N E+ Y ++P + + F IN TGEI++ +D
Sbjct: 250 VLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGELD 309
Query: 309 FEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVI 368
FE++N YEI V+ DKG P M GH VLVE+LD NDN PEV+VTSLSLPV+EDAQVGTVI
Sbjct: 310 FEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTVI 369
Query: 369 ALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARD 428
ALISVSD DSGANGQV CSLTPHVPFKLVSTYKNYYSLVLDSALDRE VSAYELVVTARD
Sbjct: 370 ALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARD 429
Query: 429 GGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENAL 488
GGSP LWATA VSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSAWDADAQ+NAL
Sbjct: 430 GGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNAL 489
Query: 489 VSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNL 548
VSYSLVERR+GE +LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD GVPPLGSN+
Sbjct: 490 VSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549
Query: 549 TLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSY 608
TLQVFVLDENDNAPALLA+PAGSAGGAVSELV RSV AGHVVAKVRAVDADSGYNAWLSY
Sbjct: 550 TLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609
Query: 609 ELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSL 668
ELQ AAVGA IPF VGLYTGEISTTR LDE D+PR RLLVLVKDHGEP+LT+TATVLVSL
Sbjct: 610 ELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLVSL 669
Query: 669 VEGSQAPKASSRASVG-VAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPTE 727
VE QAPK SSRASVG V PE ALVD+NVYLIIAICAVSSLLVLTLLLYTALRCSA PT
Sbjct: 670 VENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPPTV 729
Query: 728 GACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSL 774
C P KPTLVCSSAVGSWSYSQQRRQRVCS E PK DLMAFSPSL
Sbjct: 730 SRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776
>gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo
sapiens]
Length = 941
Score = 1203 bits (3113), Expect = 0.0
Identities = 626/767 (81%), Positives = 663/767 (86%), Gaps = 1/767 (0%)
Query: 9 GVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASK 68
G Q LLLSLLLLAAWEVGSGQLHYSVYEEA+HGTFVGRIAQDLGLELAELV RLFRVASK
Sbjct: 10 GSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69
Query: 69 RHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDN 128
RHGDLLEVNLQNGILFVNSRIDRE+LCGRS ECSIHLEVIVDRPLQVFHVDVEVKDINDN
Sbjct: 70 RHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDN 129
Query: 129 PPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKD 188
PP F EQK+ + ES LDS FPLEGASDAD+G N+LLTY LS NE F L I KKDK
Sbjct: 130 PPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDKS 189
Query: 189 KFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEV 248
P LVLRKLLDRE+ P+L LLL DGGKPE TGSV + I VLD NDN P FD+P Y+V
Sbjct: 190 ILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYKV 249
Query: 249 KMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAID 308
+ EN N T VI+LNASD DEG+N E+ Y ++P + + F IN TGEI++ +D
Sbjct: 250 VLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGELD 309
Query: 309 FEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVI 368
FE++N YEI V+ DKG P M GH VLVE+LD NDN PEV+VTSLSLPV+EDAQVGTVI
Sbjct: 310 FEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTVI 369
Query: 369 ALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARD 428
ALISVSD DSGANGQV CSLTPHVPFKLVSTYKNYYSLVLDSALDRE VSAYELVVTARD
Sbjct: 370 ALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARD 429
Query: 429 GGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENAL 488
GGSP LWATA VSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSAWDADAQ+NAL
Sbjct: 430 GGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNAL 489
Query: 489 VSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNL 548
VSYSLVERR+GE +LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD GVPPLGSN+
Sbjct: 490 VSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549
Query: 549 TLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSY 608
TLQVFVLDENDNAPALLA+PAGSAGGAVSELV RSV AGHVVAKVRAVDADSGYNAWLSY
Sbjct: 550 TLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609
Query: 609 ELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSL 668
ELQ AAVGA IPF VGLYTGEISTTR LDE D+PR RLLVLVKDHGEP+LT+TATVLVSL
Sbjct: 610 ELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLVSL 669
Query: 669 VEGSQAPKASSRASVG-VAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPTE 727
VE QAPK SSRASVG V PE ALVD+NVYLIIAICAVSSLLVLTLLLYTALRCSA PT
Sbjct: 670 VENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPPTV 729
Query: 728 GACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSL 774
C P KPTLVCSSAVGSWSYSQQRRQRVCS E PK DLMAFSPSL
Sbjct: 730 SRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776
>gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo
sapiens]
Length = 814
Score = 1203 bits (3112), Expect = 0.0
Identities = 627/797 (78%), Positives = 679/797 (85%), Gaps = 3/797 (0%)
Query: 8 LGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVAS 67
LG LLL LLLLAAW+VGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLFRVAS
Sbjct: 9 LGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68
Query: 68 KRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDIND 127
KRH DLLEV+LQNGILFVNSRIDREELCGRS ECSIHLEVIVDRPLQVFHVDVEVKD+ND
Sbjct: 69 KRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVND 128
Query: 128 NPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDK 187
NPP F V +QKL + ESR+ DSRFPLEGASDADVG N++LTY+LS ++YF+LD+ +K D+
Sbjct: 129 NPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDE 188
Query: 188 DKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYE 247
+K LVLRK LDRE+ P L LTATDGGKPE TG+V LL+ VLD NDNAP F++ YE
Sbjct: 189 NKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248
Query: 248 VKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAI 307
V+++EN N T VI+LNASD DEG N + YSF+SLV + F I+ TGEI + +
Sbjct: 249 VRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNL 308
Query: 308 DFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTV 367
DFE N Y+I +D TDKG+PPM GHCTVLV +LD+NDN PE+ +TSLSLPV+EDAQ GTV
Sbjct: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368
Query: 368 IALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTAR 427
IALISV+D DSGANGQVTCSL PHVPFKLVST+KNYYSLVLDSALDRERVSAYELVVTAR
Sbjct: 369 IALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTAR 428
Query: 428 DGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENA 487
DGGSP LWATAS+SVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQENA
Sbjct: 429 DGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488
Query: 488 LVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSN 547
LVSYSLVERR+GERSLSSY+SVH ESGKVYALQPLDHEELELLQFQVSARD GVPPLGSN
Sbjct: 489 LVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548
Query: 548 LTLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLS 607
+TLQVFVLDENDNAPALL G GGA S+LV RSV AGHVVAKVRAVDADSGYNAWLS
Sbjct: 549 VTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLS 608
Query: 608 YELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVS 667
YELQ AA RIPFRVGLYTGEISTTR LDE DSPR RLLVLVKDHGEP+LTATATVLVS
Sbjct: 609 YELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS 668
Query: 668 LVEGSQAPKASSRASVGV-APEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPT 726
LVE QAPKASSR S GV PE ALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA PT
Sbjct: 669 LVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPT 728
Query: 727 EGACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPP-CPMVDVDGE 785
EG C KPTLVCSSAVGSWSYSQQ+ QRVCSGEG PK DLMAFSP LPP VDV GE
Sbjct: 729 EGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVDV-GE 787
Query: 786 DQSIGGDHSRKVGYYVF 802
+Q + DH KV + F
Sbjct: 788 EQDLNVDHGLKVSPFKF 804
>gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens]
Length = 950
Score = 1200 bits (3104), Expect = 0.0
Identities = 625/791 (79%), Positives = 676/791 (85%), Gaps = 3/791 (0%)
Query: 8 LGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVAS 67
LG LLL LLLLAAW+VGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLFRVAS
Sbjct: 9 LGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68
Query: 68 KRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDIND 127
KRH DLLEV+LQNGILFVNSRIDREELCGRS ECSIHLEVIVDRPLQVFHVDVEVKD+ND
Sbjct: 69 KRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVND 128
Query: 128 NPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDK 187
NPP F V +QKL + ESR+ DSRFPLEGASDADVG N++LTY+LS ++YF+LD+ +K D+
Sbjct: 129 NPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDE 188
Query: 188 DKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYE 247
+K LVLRK LDRE+ P L LTATDGGKPE TG+V LL+ VLD NDNAP F++ YE
Sbjct: 189 NKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248
Query: 248 VKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAI 307
V+++EN N T VI+LNASD DEG N + YSF+SLV + F I+ TGEI + +
Sbjct: 249 VRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNL 308
Query: 308 DFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTV 367
DFE N Y+I +D TDKG+PPM GHCTVLV +LD+NDN PE+ +TSLSLPV+EDAQ GTV
Sbjct: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368
Query: 368 IALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTAR 427
IALISV+D DSGANGQVTCSL PHVPFKLVST+KNYYSLVLDSALDRERVSAYELVVTAR
Sbjct: 369 IALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTAR 428
Query: 428 DGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENA 487
DGGSP LWATAS+SVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQENA
Sbjct: 429 DGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488
Query: 488 LVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSN 547
LVSYSLVERR+GERSLSSY+SVH ESGKVYALQPLDHEELELLQFQVSARD GVPPLGSN
Sbjct: 489 LVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548
Query: 548 LTLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLS 607
+TLQVFVLDENDNAPALL G GGA S+LV RSV AGHVVAKVRAVDADSGYNAWLS
Sbjct: 549 VTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLS 608
Query: 608 YELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVS 667
YELQ AA RIPFRVGLYTGEISTTR LDE DSPR RLLVLVKDHGEP+LTATATVLVS
Sbjct: 609 YELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS 668
Query: 668 LVEGSQAPKASSRASVGV-APEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPT 726
LVE QAPKASSR S GV PE ALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA PT
Sbjct: 669 LVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPT 728
Query: 727 EGACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPP-CPMVDVDGE 785
EG C KPTLVCSSAVGSWSYSQQ+ QRVCSGEG PK DLMAFSP LPP VDV GE
Sbjct: 729 EGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVDV-GE 787
Query: 786 DQSIGGDHSRK 796
+Q + DH K
Sbjct: 788 EQDLNVDHGLK 798
>gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo
sapiens]
Length = 824
Score = 1194 bits (3088), Expect = 0.0
Identities = 621/803 (77%), Positives = 676/803 (84%), Gaps = 3/803 (0%)
Query: 9 GVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASK 68
G QCLLLSLLLLAA EVGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLFRVASK
Sbjct: 10 GAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69
Query: 69 RHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDN 128
RHGDLLEVNLQNGILFVNSRIDREELCGRS ECSIHLEVIVDRPLQVFHV+VEVKDINDN
Sbjct: 70 RHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKDINDN 129
Query: 129 PPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKD 188
P F + + L I ESR SRF LEGASDAD+G N+LLTY L EYF LD+ ++
Sbjct: 130 APVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRNDEEI 189
Query: 189 KFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEV 248
K LVL+K L+RE+ P+ LL+TA DGGKPE TG+ L I VLD NDNAP F+R +Y+V
Sbjct: 190 KSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIYKV 249
Query: 249 KMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAID 308
++ EN N TLV+ +NA+D DEG+NK++ YSF++ + I KF ++ G+I V ID
Sbjct: 250 RLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGNID 309
Query: 309 FEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVI 368
FE+S +YEI V+ TDKGNPPM HCTVL+E++D NDN PE+++ SLSLPV ED+ + TVI
Sbjct: 310 FEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSPLSTVI 369
Query: 369 ALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARD 428
ALISVSD DSG NGQVTCSLTPHVPFKLVST+KNYYSLVLDS LDRE VSAYELVVTARD
Sbjct: 370 ALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVVTARD 429
Query: 429 GGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENAL 488
GGSP LWATASVSVEVADVNDNAPAF+QSEYTVFVKENNPPGCHIFTVSA DADAQENAL
Sbjct: 430 GGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADAQENAL 489
Query: 489 VSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNL 548
VSYSLVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD GVPPLGSN+
Sbjct: 490 VSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549
Query: 549 TLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSY 608
TLQVFVLDENDNAPALL G GGAVSELV RSV AGHVVAKVRAVDADSGYNAWLSY
Sbjct: 550 TLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609
Query: 609 ELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSL 668
ELQ GARIPFRVGLYTGEISTTRALDE D+PR RLLVLVKDHGEPSLTATATVLVSL
Sbjct: 610 ELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLTATATVLVSL 669
Query: 669 VEGSQAPKASSRASVG-VAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPTE 727
VE QAPKASS+AS G PE ALVDVNVYLI+AICAVSSLLVLTLLLYTALRCSA PTE
Sbjct: 670 VESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTALRCSAPPTE 729
Query: 728 GACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCPMVDVDGEDQ 787
G CGP KPTLVCSSAVGSWSYSQQR+QRVCSGEGLPK DLMAFSPSLPPCP+ E Q
Sbjct: 730 GDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCPISRDREEKQ 789
Query: 788 SIGGDHSRKVGYYVFIF--LLCF 808
+ D S KV + F LCF
Sbjct: 790 DVDVDLSAKVSNFYLFFPKCLCF 812
>gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens]
Length = 842
Score = 1191 bits (3081), Expect = 0.0
Identities = 628/821 (76%), Positives = 683/821 (83%), Gaps = 5/821 (0%)
Query: 11 QCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASKRH 70
Q LLLSLL+LA W VGSGQLHYSV EEA HGTFVGRIAQDLGLELAELV RLF++ SK
Sbjct: 12 QPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGR 71
Query: 71 GDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDNPP 130
GDLLEVNLQNGILFVNSRIDREELCGRS ECSIHLEVIVDRPLQVFHVDVEVKDINDNPP
Sbjct: 72 GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPP 131
Query: 131 RFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKDKF 190
F T++ L I ESR LDSRFPLEGASDAD+GENALLTY+LSPNEYF LD+ + K
Sbjct: 132 VFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKP 191
Query: 191 PVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEVKM 250
LVLRKLLDREE P+L LLLTATDGGKPE TG+V LLI VLD NDNAP+FDR +Y VK+
Sbjct: 192 LGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKL 251
Query: 251 YENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAIDFE 310
EN TLVI NASD DEG+N +++YSFSS V P I+ KF ++ +G I V +DFE
Sbjct: 252 PENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFE 311
Query: 311 DSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVIAL 370
+S ++I V+ DKG PP+ GHCT+LVE++D NDN+P++ + +LS+PVKEDAQ+GTVIAL
Sbjct: 312 ESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIAL 371
Query: 371 ISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARDGG 430
ISV D D+ ANGQVTCSLTPHVPFKLVSTYKNYYSLVLD ALDRE VSAYELVVTARDGG
Sbjct: 372 ISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGG 431
Query: 431 SPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENALVS 490
SP LWATA VSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSA DADAQENALVS
Sbjct: 432 SPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVS 491
Query: 491 YSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNLTL 550
YSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD GVPPLGSN+TL
Sbjct: 492 YSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL 551
Query: 551 QVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSYEL 610
QVFVLDENDNAPALL GAVSE+VLRSV AG VV KVRAVDADSGYNAWLSYEL
Sbjct: 552 QVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLSYEL 611
Query: 611 QSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSLVE 670
Q A IPFRVGLYTGEISTTRALDETD+PRQRLLVLVKDHGEP+LTATATVLVSLVE
Sbjct: 612 QPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVSLVE 671
Query: 671 GSQAPKASSRASVG-VAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPTEGA 729
QAPK+SSRASVG PEV LVDVNVYLIIAICAVSSLLVLTLLLYT LRCSA PTEG
Sbjct: 672 SGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMPTEGE 731
Query: 730 CGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCPMVDVDGEDQSI 789
C P KPTLVCSSAVGSWSYSQQRRQRVCSGEG K DLMAFSP L PC + S
Sbjct: 732 CAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCAGSTERTGEPSA 791
Query: 790 GGDHSRKVGY--YVFIFLLCFMNNIFSYRIFSNMYQNISFL 828
D + KVG+ +FI+++ F+ YR+ Q + F+
Sbjct: 792 SSDSTGKVGFSSILFIYIIFFLERY--YRLLPGAVQIVLFI 830
>gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo
sapiens]
Length = 810
Score = 1189 bits (3077), Expect = 0.0
Identities = 622/793 (78%), Positives = 672/793 (84%), Gaps = 2/793 (0%)
Query: 8 LGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVAS 67
LG L L LLLL WEVGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELVQRLFRVAS
Sbjct: 9 LGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRVAS 68
Query: 68 KRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDIND 127
K HGDLLEVNLQNGILFVNSRIDREELCG+S ECSIHLEVIVDRPLQVFHV+VEVKDIND
Sbjct: 69 KTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDIND 128
Query: 128 NPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDK 187
NPP FS+ EQKL I ES+ DSRFPLEGASDAD+ ENALLTY+LS NEYF LD +
Sbjct: 129 NPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNGKQ 188
Query: 188 DKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYE 247
K L+L+K LDRE+ P+L LLLTATDGGKPE TG+V LL+ VLD NDN P FD+ Y+
Sbjct: 189 IKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSEYK 248
Query: 248 VKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAI 307
V + EN +TLV++LNA+D DEG+N E+ YS S + P R F +++ GE++VN +
Sbjct: 249 VSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVNGTL 307
Query: 308 DFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTV 367
D+E++ Y+I V TDKG PPM GHCTV VE+LD NDNSPEV VTSLSLPV+EDAQ TV
Sbjct: 308 DYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPSTV 367
Query: 368 IALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTAR 427
IALISVSD DSG NGQVTCSLTPHVPFKLVST+KNYYSLVLDSALDRE V AYELVVTAR
Sbjct: 368 IALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVTAR 427
Query: 428 DGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENA 487
DGGSP LWATA VSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQENA
Sbjct: 428 DGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 487
Query: 488 LVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSN 547
LVSYSLVERRLG+R+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD GVPPL SN
Sbjct: 488 LVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLSSN 547
Query: 548 LTLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLS 607
+TLQVFVLDENDNAPALLA+ AGSAGGAV++LV RSV AGHVVAKVRAVDADSGYNAWLS
Sbjct: 548 VTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNAWLS 607
Query: 608 YELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVS 667
YELQ AA G+RIPFRVGLYTGEISTTRALDE DSPR RLLVLVKDHGEP+LTATATVLVS
Sbjct: 608 YELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVS 667
Query: 668 LVEGSQAPKASSRASVGVA-PEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPT 726
LVE QAPKASSR G A PE ALVDVNVYLIIAIC VSSLLVLTLLLYTAL SA PT
Sbjct: 668 LVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSATPT 727
Query: 727 EGACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCPMVDVDGED 786
EGAC P KPTLVCS AVGSWSYSQQRRQRVCS EG PK DLMAFSPSLP + +GE
Sbjct: 728 EGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNKEEEGER 787
Query: 787 QSIGGDHSRKVGY 799
Q G +H +V +
Sbjct: 788 QEPGSNHPGQVSF 800
>gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens]
Length = 950
Score = 1188 bits (3073), Expect = 0.0
Identities = 616/789 (78%), Positives = 670/789 (84%), Gaps = 1/789 (0%)
Query: 9 GVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASK 68
G QCLLLSLLLLAA EVGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLFRVASK
Sbjct: 10 GAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69
Query: 69 RHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDN 128
RHGDLLEVNLQNGILFVNSRIDREELCGRS ECSIHLEVIVDRPLQVFHV+VEVKDINDN
Sbjct: 70 RHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKDINDN 129
Query: 129 PPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKD 188
P F + + L I ESR SRF LEGASDAD+G N+LLTY L EYF LD+ ++
Sbjct: 130 APVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRNDEEI 189
Query: 189 KFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEV 248
K LVL+K L+RE+ P+ LL+TA DGGKPE TG+ L I VLD NDNAP F+R +Y+V
Sbjct: 190 KSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIYKV 249
Query: 249 KMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAID 308
++ EN N TLV+ +NA+D DEG+NK++ YSF++ + I KF ++ G+I V ID
Sbjct: 250 RLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGNID 309
Query: 309 FEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVI 368
FE+S +YEI V+ TDKGNPPM HCTVL+E++D NDN PE+++ SLSLPV ED+ + TVI
Sbjct: 310 FEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSPLSTVI 369
Query: 369 ALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARD 428
ALISVSD DSG NGQVTCSLTPHVPFKLVST+KNYYSLVLDS LDRE VSAYELVVTARD
Sbjct: 370 ALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVVTARD 429
Query: 429 GGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENAL 488
GGSP LWATASVSVEVADVNDNAPAF+QSEYTVFVKENNPPGCHIFTVSA DADAQENAL
Sbjct: 430 GGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADAQENAL 489
Query: 489 VSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNL 548
VSYSLVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD GVPPLGSN+
Sbjct: 490 VSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549
Query: 549 TLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSY 608
TLQVFVLDENDNAPALL G GGAVSELV RSV AGHVVAKVRAVDADSGYNAWLSY
Sbjct: 550 TLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609
Query: 609 ELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSL 668
ELQ GARIPFRVGLYTGEISTTRALDE D+PR RLLVLVKDHGEPSLTATATVLVSL
Sbjct: 610 ELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLTATATVLVSL 669
Query: 669 VEGSQAPKASSRASVG-VAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPTE 727
VE QAPKASS+AS G PE ALVDVNVYLI+AICAVSSLLVLTLLLYTALRCSA PTE
Sbjct: 670 VESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTALRCSAPPTE 729
Query: 728 GACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCPMVDVDGEDQ 787
G CGP KPTLVCSSAVGSWSYSQQR+QRVCSGEGLPK DLMAFSPSLPPCP+ E Q
Sbjct: 730 GDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCPISRDREEKQ 789
Query: 788 SIGGDHSRK 796
+ D S K
Sbjct: 790 DVDVDLSAK 798
>gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo
sapiens]
Length = 949
Score = 1187 bits (3072), Expect = 0.0
Identities = 621/787 (78%), Positives = 669/787 (85%), Gaps = 2/787 (0%)
Query: 8 LGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVAS 67
LG L L LLLL WEVGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELVQRLFRVAS
Sbjct: 9 LGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRVAS 68
Query: 68 KRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDIND 127
K HGDLLEVNLQNGILFVNSRIDREELCG+S ECSIHLEVIVDRPLQVFHV+VEVKDIND
Sbjct: 69 KTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDIND 128
Query: 128 NPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDK 187
NPP FS+ EQKL I ES+ DSRFPLEGASDAD+ ENALLTY+LS NEYF LD +
Sbjct: 129 NPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNGKQ 188
Query: 188 DKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYE 247
K L+L+K LDRE+ P+L LLLTATDGGKPE TG+V LL+ VLD NDN P FD+ Y+
Sbjct: 189 IKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSEYK 248
Query: 248 VKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAI 307
V + EN +TLV++LNA+D DEG+N E+ YS S + P R F +++ GE++VN +
Sbjct: 249 VSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVNGTL 307
Query: 308 DFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTV 367
D+E++ Y+I V TDKG PPM GHCTV VE+LD NDNSPEV VTSLSLPV+EDAQ TV
Sbjct: 308 DYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPSTV 367
Query: 368 IALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTAR 427
IALISVSD DSG NGQVTCSLTPHVPFKLVST+KNYYSLVLDSALDRE V AYELVVTAR
Sbjct: 368 IALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVTAR 427
Query: 428 DGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENA 487
DGGSP LWATA VSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQENA
Sbjct: 428 DGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 487
Query: 488 LVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSN 547
LVSYSLVERRLG+R+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD GVPPL SN
Sbjct: 488 LVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLSSN 547
Query: 548 LTLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLS 607
+TLQVFVLDENDNAPALLA+ AGSAGGAV++LV RSV AGHVVAKVRAVDADSGYNAWLS
Sbjct: 548 VTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNAWLS 607
Query: 608 YELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVS 667
YELQ AA G+RIPFRVGLYTGEISTTRALDE DSPR RLLVLVKDHGEP+LTATATVLVS
Sbjct: 608 YELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVS 667
Query: 668 LVEGSQAPKASSRASVGVA-PEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPT 726
LVE QAPKASSR G A PE ALVDVNVYLIIAIC VSSLLVLTLLLYTAL SA PT
Sbjct: 668 LVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSATPT 727
Query: 727 EGACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCPMVDVDGED 786
EGAC P KPTLVCS AVGSWSYSQQRRQRVCS EG PK DLMAFSPSLP + +GE
Sbjct: 728 EGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNKEEEGER 787
Query: 787 QSIGGDH 793
Q G +H
Sbjct: 788 QEPGSNH 794
>gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo
sapiens]
Length = 798
Score = 1184 bits (3064), Expect = 0.0
Identities = 620/776 (79%), Positives = 668/776 (86%), Gaps = 5/776 (0%)
Query: 13 LLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASKRHGD 72
LLL LLLLAAWE G+GQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLFRVASK G
Sbjct: 14 LLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGG 73
Query: 73 LLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDNPPRF 132
LLEVNLQNGILFVNSRIDREELC RS ECSIHLEVIVDRPLQVFHVDVEV+DINDNPP F
Sbjct: 74 LLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPVF 133
Query: 133 SVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKDKFPV 192
T++ LSI ESR LDSRFPLEGASDAD+GENALLTY+LSPNEYF L+ + K
Sbjct: 134 PATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKGLG 193
Query: 193 LVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEVKMYE 252
L+LRK LDREE P++ L+LTATDGGKPE TG+V LLI VLDANDNAP FDR +Y+V++ E
Sbjct: 194 LILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRLLE 253
Query: 253 NQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAIDFEDS 312
N N TLVI+LNASD DEG+N +++YSFS+ + P ++ KF I+ TG+I V IDFE+S
Sbjct: 254 NVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFEES 313
Query: 313 NTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVIALIS 372
+YEI V+ DKG P+ GHC V+VE+ D NDN P++ SLSLP++EDA +GTVIALIS
Sbjct: 314 KSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTVIALIS 373
Query: 373 VSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARDGGSP 432
VSD D G NG VTCSLT HVPFKLVST+KNYYSLVLDSALDRE VSAYELVVTARDGGSP
Sbjct: 374 VSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433
Query: 433 PLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS 492
LWATASVSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS
Sbjct: 434 SLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS 493
Query: 493 LVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNLTLQV 552
LVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARD GVPPLGSN+TLQV
Sbjct: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGSNVTLQV 553
Query: 553 FVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSYELQS 612
FVLDENDNAPALLA AG GGAVSELV SV GHVVAKVRAVDADSGYNAWLSYELQ
Sbjct: 554 FVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWLSYELQP 613
Query: 613 AAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSLVEGS 672
GARIPFRVGLYTGEISTTRALDETD+PR RLLVLVKDHGEP+LTATATVLVSLVE
Sbjct: 614 GTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLVSLVESG 673
Query: 673 QAPKASSRASVG-VAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPTEGACG 731
QAPKASSRA VG V P+ ALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA PTEGAC
Sbjct: 674 QAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTEGACA 733
Query: 732 PVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCPMVDVDGEDQ 787
P KPTLVCSSAVGSWSYSQQRR RVCSGEG PK DLMAFSPSLP D EDQ
Sbjct: 734 PGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPD----SRDREDQ 785
>gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens]
Length = 947
Score = 1184 bits (3064), Expect = 0.0
Identities = 620/776 (79%), Positives = 668/776 (86%), Gaps = 5/776 (0%)
Query: 13 LLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASKRHGD 72
LLL LLLLAAWE G+GQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLFRVASK G
Sbjct: 14 LLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGG 73
Query: 73 LLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDNPPRF 132
LLEVNLQNGILFVNSRIDREELC RS ECSIHLEVIVDRPLQVFHVDVEV+DINDNPP F
Sbjct: 74 LLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPVF 133
Query: 133 SVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKDKFPV 192
T++ LSI ESR LDSRFPLEGASDAD+GENALLTY+LSPNEYF L+ + K
Sbjct: 134 PATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKGLG 193
Query: 193 LVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEVKMYE 252
L+LRK LDREE P++ L+LTATDGGKPE TG+V LLI VLDANDNAP FDR +Y+V++ E
Sbjct: 194 LILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRLLE 253
Query: 253 NQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAIDFEDS 312
N N TLVI+LNASD DEG+N +++YSFS+ + P ++ KF I+ TG+I V IDFE+S
Sbjct: 254 NVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFEES 313
Query: 313 NTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVIALIS 372
+YEI V+ DKG P+ GHC V+VE+ D NDN P++ SLSLP++EDA +GTVIALIS
Sbjct: 314 KSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTVIALIS 373
Query: 373 VSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARDGGSP 432
VSD D G NG VTCSLT HVPFKLVST+KNYYSLVLDSALDRE VSAYELVVTARDGGSP
Sbjct: 374 VSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433
Query: 433 PLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS 492
LWATASVSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS
Sbjct: 434 SLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS 493
Query: 493 LVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNLTLQV 552
LVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARD GVPPLGSN+TLQV
Sbjct: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGSNVTLQV 553
Query: 553 FVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSYELQS 612
FVLDENDNAPALLA AG GGAVSELV SV GHVVAKVRAVDADSGYNAWLSYELQ
Sbjct: 554 FVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWLSYELQP 613
Query: 613 AAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSLVEGS 672
GARIPFRVGLYTGEISTTRALDETD+PR RLLVLVKDHGEP+LTATATVLVSLVE
Sbjct: 614 GTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLVSLVESG 673
Query: 673 QAPKASSRASVG-VAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPTEGACG 731
QAPKASSRA VG V P+ ALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA PTEGAC
Sbjct: 674 QAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTEGACA 733
Query: 732 PVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCPMVDVDGEDQ 787
P KPTLVCSSAVGSWSYSQQRR RVCSGEG PK DLMAFSPSLP D EDQ
Sbjct: 734 PGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPD----SRDREDQ 785
>gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo
sapiens]
Length = 950
Score = 1180 bits (3052), Expect = 0.0
Identities = 616/768 (80%), Positives = 660/768 (85%), Gaps = 1/768 (0%)
Query: 11 QCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASKRH 70
Q LLLSLL+LA W VGSGQLHYSV EEA HGTFVGRIAQDLGLELAELV RLF++ SK
Sbjct: 12 QPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGR 71
Query: 71 GDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDNPP 130
GDLLEVNLQNGILFVNSRIDREELCGRS ECSIHLEVIVDRPLQVFHVDVEVKDINDNPP
Sbjct: 72 GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPP 131
Query: 131 RFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKDKF 190
F T++ L I ESR LDSRFPLEGASDAD+GENALLTY+LSPNEYF LD+ + K
Sbjct: 132 VFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKP 191
Query: 191 PVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEVKM 250
LVLRKLLDREE P+L LLLTATDGGKPE TG+V LLI VLD NDNAP+FDR +Y VK+
Sbjct: 192 LGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKL 251
Query: 251 YENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAIDFE 310
EN TLVI NASD DEG+N +++YSFSS V P I+ KF ++ +G I V +DFE
Sbjct: 252 PENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFE 311
Query: 311 DSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVIAL 370
+S ++I V+ DKG PP+ GHCT+LVE++D NDN+P++ + +LS+PVKEDAQ+GTVIAL
Sbjct: 312 ESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIAL 371
Query: 371 ISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARDGG 430
ISV D D+ ANGQVTCSLTPHVPFKLVSTYKNYYSLVLD ALDRE VSAYELVVTARDGG
Sbjct: 372 ISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGG 431
Query: 431 SPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENALVS 490
SP LWATA VSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSA DADAQENALVS
Sbjct: 432 SPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVS 491
Query: 491 YSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNLTL 550
YSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD GVPPLGSN+TL
Sbjct: 492 YSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL 551
Query: 551 QVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSYEL 610
QVFVLDENDNAPALL GAVSE+VLRSV AG VV KVRAVDADSGYNAWLSYEL
Sbjct: 552 QVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLSYEL 611
Query: 611 QSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSLVE 670
Q A IPFRVGLYTGEISTTRALDETD+PRQRLLVLVKDHGEP+LTATATVLVSLVE
Sbjct: 612 QPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVSLVE 671
Query: 671 GSQAPKASSRASVG-VAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPTEGA 729
QAPK+SSRASVG PEV LVDVNVYLIIAICAVSSLLVLTLLLYT LRCSA PTEG
Sbjct: 672 SGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMPTEGE 731
Query: 730 CGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPC 777
C P KPTLVCSSAVGSWSYSQQRRQRVCSGEG K DLMAFSP L PC
Sbjct: 732 CAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPC 779
>gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo
sapiens]
Length = 789
Score = 1178 bits (3047), Expect = 0.0
Identities = 614/771 (79%), Positives = 662/771 (85%), Gaps = 1/771 (0%)
Query: 9 GVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASK 68
G + LLL +++LAAWE G GQLHYSV EEA+HG FVGRIAQDLGLELAELV RLFR K
Sbjct: 10 GGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCK 69
Query: 69 RHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDN 128
GDLLEVNLQNGILFVNSRIDREELCGRS ECSIHLEVIV+RPLQVFHVDVEVKDINDN
Sbjct: 70 FRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDN 129
Query: 129 PPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKD 188
PP F T++ L I ESR LDSRFPLEGASDAD+GENALLTY+LSPNEYF LD+ +
Sbjct: 130 PPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQV 189
Query: 189 KFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEV 248
K LVLRKLLDREE P+L LLLTATDGGKPE TG+V LLI VLD NDNAP+FDR +Y V
Sbjct: 190 KPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTV 249
Query: 249 KMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAID 308
K+ EN TLVI NASD DEG+N +++YSFSS V P I+ KF ++ +G I V +D
Sbjct: 250 KLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMD 309
Query: 309 FEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVI 368
FE+S ++I V+ DKG PP+ GHCTVLVE++D NDN+P++ +TSLSLP+ EDAQ GTVI
Sbjct: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369
Query: 369 ALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARD 428
LISV D D G NGQVTCSLTP VPFKLVST+KNYYSLVLDSALDRE VSAYELVVTARD
Sbjct: 370 TLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429
Query: 429 GGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENAL 488
GGSP LWATASVSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQ+NAL
Sbjct: 430 GGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNAL 489
Query: 489 VSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNL 548
VSYSLVE R+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD GVPPLGSN+
Sbjct: 490 VSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549
Query: 549 TLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSY 608
TLQVFVLDENDNAPALLA G GGAV ELV RSV AGHVVAKVRAVDADSGYNAWLSY
Sbjct: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609
Query: 609 ELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSL 668
ELQ A GA IPFRVGLYTGEISTTRALDETD+PR RLLVLVKDHGEPSLTATATVLVSL
Sbjct: 610 ELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSL 669
Query: 669 VEGSQAPKASSRASVGVA-PEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPTE 727
VE QAPKASSRAS+G+A PE LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA +E
Sbjct: 670 VESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSE 729
Query: 728 GACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCP 778
GAC VKPTLVCSSAVGSWS+SQQRRQRVCSGEG PK DLMAFSPSLP P
Sbjct: 730 GACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP 780
>gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens]
Length = 937
Score = 1178 bits (3047), Expect = 0.0
Identities = 614/771 (79%), Positives = 662/771 (85%), Gaps = 1/771 (0%)
Query: 9 GVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASK 68
G + LLL +++LAAWE G GQLHYSV EEA+HG FVGRIAQDLGLELAELV RLFR K
Sbjct: 10 GGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCK 69
Query: 69 RHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDN 128
GDLLEVNLQNGILFVNSRIDREELCGRS ECSIHLEVIV+RPLQVFHVDVEVKDINDN
Sbjct: 70 FRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDN 129
Query: 129 PPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKD 188
PP F T++ L I ESR LDSRFPLEGASDAD+GENALLTY+LSPNEYF LD+ +
Sbjct: 130 PPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQV 189
Query: 189 KFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEV 248
K LVLRKLLDREE P+L LLLTATDGGKPE TG+V LLI VLD NDNAP+FDR +Y V
Sbjct: 190 KPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTV 249
Query: 249 KMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAID 308
K+ EN TLVI NASD DEG+N +++YSFSS V P I+ KF ++ +G I V +D
Sbjct: 250 KLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMD 309
Query: 309 FEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVI 368
FE+S ++I V+ DKG PP+ GHCTVLVE++D NDN+P++ +TSLSLP+ EDAQ GTVI
Sbjct: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369
Query: 369 ALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARD 428
LISV D D G NGQVTCSLTP VPFKLVST+KNYYSLVLDSALDRE VSAYELVVTARD
Sbjct: 370 TLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429
Query: 429 GGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENAL 488
GGSP LWATASVSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQ+NAL
Sbjct: 430 GGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNAL 489
Query: 489 VSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNL 548
VSYSLVE R+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD GVPPLGSN+
Sbjct: 490 VSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549
Query: 549 TLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSY 608
TLQVFVLDENDNAPALLA G GGAV ELV RSV AGHVVAKVRAVDADSGYNAWLSY
Sbjct: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609
Query: 609 ELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSL 668
ELQ A GA IPFRVGLYTGEISTTRALDETD+PR RLLVLVKDHGEPSLTATATVLVSL
Sbjct: 610 ELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSL 669
Query: 669 VEGSQAPKASSRASVGVA-PEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPTE 727
VE QAPKASSRAS+G+A PE LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA +E
Sbjct: 670 VESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSE 729
Query: 728 GACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCP 778
GAC VKPTLVCSSAVGSWS+SQQRRQRVCSGEG PK DLMAFSPSLP P
Sbjct: 730 GACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP 780
>gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo
sapiens]
Length = 807
Score = 1175 bits (3039), Expect = 0.0
Identities = 605/766 (78%), Positives = 659/766 (86%), Gaps = 1/766 (0%)
Query: 13 LLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASKRHGD 72
LLL LL+LAAWE GSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLFRVASKRHGD
Sbjct: 14 LLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGD 73
Query: 73 LLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDNPPRF 132
LLEVNLQNGILFVNSRIDREELCGRS ECSIHLEVIVDRPLQVFHV+V+V+DINDNPP F
Sbjct: 74 LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDINDNPPIF 133
Query: 133 SVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKDKFPV 192
+++++ I ESR ++RFPL+GASDAD+G N+ LTY+L PN+YF LD N ++
Sbjct: 134 PESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLEQMSSLS 193
Query: 193 LVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEVKMYE 252
LVLRK LDREE + LLLTA+DGGKPE TG+V LLI +LD NDNAP F + VY+V + E
Sbjct: 194 LVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVYKVTVLE 253
Query: 253 NQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAIDFEDS 312
N N TLVI+LNA+D D+G N +++YSF V P + F IN GEI+ +DFE+
Sbjct: 254 NAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGKLDFEEK 313
Query: 313 NTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVIALIS 372
YEI V+ DKGN PM GHCT+LVE+LD NDN+PEV +TSLSLP++ED Q +IALIS
Sbjct: 314 KLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPSAIIALIS 373
Query: 373 VSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARDGGSP 432
VSD DSG+NGQVTC+LTPHVPFKLVSTYKNYYSLVLDSALDRE VSAYELVVTARDGGSP
Sbjct: 374 VSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433
Query: 433 PLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS 492
LWATASVSV VADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQENALVSYS
Sbjct: 434 SLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQENALVSYS 493
Query: 493 LVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNLTLQV 552
LVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD GVPPLGSN+TLQV
Sbjct: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLGSNVTLQV 553
Query: 553 FVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSYELQS 612
FVLDENDNAPALL AGSAGG VSEL+ RSV AGHVVAKVRAVDADSGYNAWLSYELQ
Sbjct: 554 FVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWLSYELQL 613
Query: 613 AAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSLVEGS 672
AAVGARIPFRVGLYTGEISTTR LDE D+P RLLVLVKDHGEP+LTATATVL+SLVE
Sbjct: 614 AAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVLLSLVESG 673
Query: 673 QAPKASSRASVG-VAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPTEGACG 731
QAP+ASSRAS G V PE ALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA PTEGAC
Sbjct: 674 QAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACA 733
Query: 732 PVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPC 777
P KPTLVCSSA GSWSYSQQRR RVCSGEG K DLMAFSPSLPPC
Sbjct: 734 PGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPC 779
>gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo
sapiens]
Length = 950
Score = 1175 bits (3039), Expect = 0.0
Identities = 605/766 (78%), Positives = 659/766 (86%), Gaps = 1/766 (0%)
Query: 13 LLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASKRHGD 72
LLL LL+LAAWE GSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLFRVASKRHGD
Sbjct: 14 LLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGD 73
Query: 73 LLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDNPPRF 132
LLEVNLQNGILFVNSRIDREELCGRS ECSIHLEVIVDRPLQVFHV+V+V+DINDNPP F
Sbjct: 74 LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDINDNPPIF 133
Query: 133 SVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKDKFPV 192
+++++ I ESR ++RFPL+GASDAD+G N+ LTY+L PN+YF LD N ++
Sbjct: 134 PESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLEQMSSLS 193
Query: 193 LVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEVKMYE 252
LVLRK LDREE + LLLTA+DGGKPE TG+V LLI +LD NDNAP F + VY+V + E
Sbjct: 194 LVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVYKVTVLE 253
Query: 253 NQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAIDFEDS 312
N N TLVI+LNA+D D+G N +++YSF V P + F IN GEI+ +DFE+
Sbjct: 254 NAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGKLDFEEK 313
Query: 313 NTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVIALIS 372
YEI V+ DKGN PM GHCT+LVE+LD NDN+PEV +TSLSLP++ED Q +IALIS
Sbjct: 314 KLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPSAIIALIS 373
Query: 373 VSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARDGGSP 432
VSD DSG+NGQVTC+LTPHVPFKLVSTYKNYYSLVLDSALDRE VSAYELVVTARDGGSP
Sbjct: 374 VSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433
Query: 433 PLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS 492
LWATASVSV VADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQENALVSYS
Sbjct: 434 SLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQENALVSYS 493
Query: 493 LVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNLTLQV 552
LVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD GVPPLGSN+TLQV
Sbjct: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLGSNVTLQV 553
Query: 553 FVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSYELQS 612
FVLDENDNAPALL AGSAGG VSEL+ RSV AGHVVAKVRAVDADSGYNAWLSYELQ
Sbjct: 554 FVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWLSYELQL 613
Query: 613 AAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSLVEGS 672
AAVGARIPFRVGLYTGEISTTR LDE D+P RLLVLVKDHGEP+LTATATVL+SLVE
Sbjct: 614 AAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVLLSLVESG 673
Query: 673 QAPKASSRASVG-VAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPTEGACG 731
QAP+ASSRAS G V PE ALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA PTEGAC
Sbjct: 674 QAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACA 733
Query: 732 PVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPC 777
P KPTLVCSSA GSWSYSQQRR RVCSGEG K DLMAFSPSLPPC
Sbjct: 734 PGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPC 779
>gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens]
Length = 936
Score = 1174 bits (3036), Expect = 0.0
Identities = 612/777 (78%), Positives = 664/777 (85%), Gaps = 2/777 (0%)
Query: 3 SRCSCLGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRL 62
SR LG + LLL LLLA W+ GSGQLHYS+ EEA+HGTFVGRIAQDLGLELAELV RL
Sbjct: 4 SRRGSLGSRLLLL-WLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRL 62
Query: 63 FRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEV 122
FRVASK GDLLEVNLQNGILFVNSRIDREELC R ECSIHLEVIVDRPLQVFHV+V V
Sbjct: 63 FRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAV 122
Query: 123 KDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDII 182
KDINDNPPRFS EQ+L I ESR+ DSRFPLEGASD D+G NA L Y+L+PNEYF LD+
Sbjct: 123 KDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVK 182
Query: 183 NKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFD 242
+++ F LVLRK LDREE + +LL+ ATDGGKPE TG+V LLI VLDANDNAP FD
Sbjct: 183 TNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFD 242
Query: 243 RPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIK 302
+ +Y V++ EN + TLVI+LNASD+DEGINKE++Y FS+LV ++ KF IN TGEIK
Sbjct: 243 KSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIK 302
Query: 303 VNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDA 362
VN +D+ED N+YEI++D DK P+ GHC V+V+LLD NDN+PE+ +T+L LPVKEDA
Sbjct: 303 VNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDA 362
Query: 363 QVGTVIALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYEL 422
+ TVIALISVSD DSGANGQVTCSL PHVPFKLVST+KNYYSLVLDSALDRE VS YEL
Sbjct: 363 PLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYEL 422
Query: 423 VVTARDGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDAD 482
VVTARDGGSP LWATASVSVEVADVNDNAPAFAQ +YTVFVKENNPPGCHIFTVSA DAD
Sbjct: 423 VVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDAD 482
Query: 483 AQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVP 542
AQENALVSYSLVERR+GER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARD GVP
Sbjct: 483 AQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVP 542
Query: 543 PLGSNLTLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGY 602
PLGSN+TLQVFVLDENDNAPALL G GGAVSELV RSV AGHVVAKVRAVD DSGY
Sbjct: 543 PLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGY 602
Query: 603 NAWLSYELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATA 662
NAWLSYELQ A ARIPFRVGLYTGEISTTR+LDET++PR RLLVLVKDHGEP LTATA
Sbjct: 603 NAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATA 662
Query: 663 TVLVSLVEGSQAPKASSRASVG-VAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRC 721
TVLVSLVE QAPKASSRAS G V PE ALVDVNVYLIIAICAVSSLLVLTLLLYTALRC
Sbjct: 663 TVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRC 722
Query: 722 SAAPTEGACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCP 778
SA PTE C KPTL+CSSAVGSWSYSQQRRQRVCSGE PK DLMAFSPSLP P
Sbjct: 723 SAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGP 779
>gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo
sapiens]
Length = 816
Score = 1174 bits (3036), Expect = 0.0
Identities = 612/777 (78%), Positives = 664/777 (85%), Gaps = 2/777 (0%)
Query: 3 SRCSCLGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRL 62
SR LG + LLL LLLA W+ GSGQLHYS+ EEA+HGTFVGRIAQDLGLELAELV RL
Sbjct: 4 SRRGSLGSRLLLL-WLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRL 62
Query: 63 FRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEV 122
FRVASK GDLLEVNLQNGILFVNSRIDREELC R ECSIHLEVIVDRPLQVFHV+V V
Sbjct: 63 FRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAV 122
Query: 123 KDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDII 182
KDINDNPPRFS EQ+L I ESR+ DSRFPLEGASD D+G NA L Y+L+PNEYF LD+
Sbjct: 123 KDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVK 182
Query: 183 NKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFD 242
+++ F LVLRK LDREE + +LL+ ATDGGKPE TG+V LLI VLDANDNAP FD
Sbjct: 183 TNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFD 242
Query: 243 RPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIK 302
+ +Y V++ EN + TLVI+LNASD+DEGINKE++Y FS+LV ++ KF IN TGEIK
Sbjct: 243 KSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIK 302
Query: 303 VNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDA 362
VN +D+ED N+YEI++D DK P+ GHC V+V+LLD NDN+PE+ +T+L LPVKEDA
Sbjct: 303 VNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDA 362
Query: 363 QVGTVIALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYEL 422
+ TVIALISVSD DSGANGQVTCSL PHVPFKLVST+KNYYSLVLDSALDRE VS YEL
Sbjct: 363 PLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYEL 422
Query: 423 VVTARDGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDAD 482
VVTARDGGSP LWATASVSVEVADVNDNAPAFAQ +YTVFVKENNPPGCHIFTVSA DAD
Sbjct: 423 VVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDAD 482
Query: 483 AQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVP 542
AQENALVSYSLVERR+GER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARD GVP
Sbjct: 483 AQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVP 542
Query: 543 PLGSNLTLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGY 602
PLGSN+TLQVFVLDENDNAPALL G GGAVSELV RSV AGHVVAKVRAVD DSGY
Sbjct: 543 PLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGY 602
Query: 603 NAWLSYELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATA 662
NAWLSYELQ A ARIPFRVGLYTGEISTTR+LDET++PR RLLVLVKDHGEP LTATA
Sbjct: 603 NAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATA 662
Query: 663 TVLVSLVEGSQAPKASSRASVG-VAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRC 721
TVLVSLVE QAPKASSRAS G V PE ALVDVNVYLIIAICAVSSLLVLTLLLYTALRC
Sbjct: 663 TVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRC 722
Query: 722 SAAPTEGACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCP 778
SA PTE C KPTL+CSSAVGSWSYSQQRRQRVCSGE PK DLMAFSPSLP P
Sbjct: 723 SAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGP 779
>gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo
sapiens]
Length = 824
Score = 1169 bits (3024), Expect = 0.0
Identities = 612/796 (76%), Positives = 668/796 (83%), Gaps = 3/796 (0%)
Query: 9 GVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASK 68
G LLSLLLLAAWEVGSGQL YSV EEA+HGTFVGRIAQDLGLEL ELV RLFRVASK
Sbjct: 10 GAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASK 69
Query: 69 RHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDN 128
RHGDLLEVNLQNGILFVNSRIDREELCGRS ECSIH+EVIVDRPLQVFHV+VEVKDINDN
Sbjct: 70 RHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDN 129
Query: 129 PPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKD 188
PP F +T + + PESRLLDSRFPLEGASDAD+G NALL+YKLS +E+F LDI +
Sbjct: 130 PPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELS 189
Query: 189 KFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEV 248
+ LVL K LDREE ++ LLL ATDGGKPE TG+V +LI VLD NDN P F + VY+V
Sbjct: 190 ESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKV 249
Query: 249 KMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAID 308
K+ EN N TLV++LNASD+DEG N E++YS S V TI+ KF I+ +GEI+ +D
Sbjct: 250 KLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLD 309
Query: 309 FEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVI 368
+E++ +YEI V TDKG P M GHC + ++L+D NDN+PEV +TSLSLP+ E+A +GTVI
Sbjct: 310 YEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVI 369
Query: 369 ALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARD 428
ALI+VSD DSG NG VTCSLTPHVPFKLVST+KNYYSLVLDSALDRE VSAYELVVTARD
Sbjct: 370 ALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429
Query: 429 GGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENAL 488
GGSP LWAT SVS+EVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSAWDADAQENAL
Sbjct: 430 GGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENAL 489
Query: 489 VSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNL 548
VSYSLVERR+GER+LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARD GVPPLGSN+
Sbjct: 490 VSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNV 549
Query: 549 TLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSY 608
TLQVFVLDENDNAPALLA AG+A GAVSELV SV AGHVVAKVRAVDADSGYNAWLSY
Sbjct: 550 TLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSY 609
Query: 609 ELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSL 668
ELQ ARIPFRVGLYTGEISTTRALDE DSPR RLLVLVKDHGEP+LTATATVLVSL
Sbjct: 610 ELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669
Query: 669 VEGSQAPKASSRASVGVA-PEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPTE 727
VE QAPKASSRA VG A E LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS PTE
Sbjct: 670 VESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTE 729
Query: 728 GACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCPMVDVDGEDQ 787
GA P KPTLVCSSAVGSWSYSQQRRQRVCSGE PK DLMAFSPSL P D E Q
Sbjct: 730 GARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP--DSAEEKQ 787
Query: 788 SIGGDHSRKVGYYVFI 803
++ KV +F+
Sbjct: 788 LSESEYVGKVSLLLFL 803
>gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens]
Length = 948
Score = 1167 bits (3018), Expect = 0.0
Identities = 606/771 (78%), Positives = 658/771 (85%), Gaps = 1/771 (0%)
Query: 9 GVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASK 68
G LLSLLLLAAWEVGSGQL YSV EEA+HGTFVGRIAQDLGLEL ELV RLFRVASK
Sbjct: 10 GAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASK 69
Query: 69 RHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDN 128
RHGDLLEVNLQNGILFVNSRIDREELCGRS ECSIH+EVIVDRPLQVFHV+VEVKDINDN
Sbjct: 70 RHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDN 129
Query: 129 PPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKD 188
PP F +T + + PESRLLDSRFPLEGASDAD+G NALL+YKLS +E+F LDI +
Sbjct: 130 PPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELS 189
Query: 189 KFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEV 248
+ LVL K LDREE ++ LLL ATDGGKPE TG+V +LI VLD NDN P F + VY+V
Sbjct: 190 ESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKV 249
Query: 249 KMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAID 308
K+ EN N TLV++LNASD+DEG N E++YS S V TI+ KF I+ +GEI+ +D
Sbjct: 250 KLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLD 309
Query: 309 FEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVI 368
+E++ +YEI V TDKG P M GHC + ++L+D NDN+PEV +TSLSLP+ E+A +GTVI
Sbjct: 310 YEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVI 369
Query: 369 ALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARD 428
ALI+VSD DSG NG VTCSLTPHVPFKLVST+KNYYSLVLDSALDRE VSAYELVVTARD
Sbjct: 370 ALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429
Query: 429 GGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENAL 488
GGSP LWAT SVS+EVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSAWDADAQENAL
Sbjct: 430 GGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENAL 489
Query: 489 VSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNL 548
VSYSLVERR+GER+LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARD GVPPLGSN+
Sbjct: 490 VSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNV 549
Query: 549 TLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSY 608
TLQVFVLDENDNAPALLA AG+A GAVSELV SV AGHVVAKVRAVDADSGYNAWLSY
Sbjct: 550 TLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSY 609
Query: 609 ELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSL 668
ELQ ARIPFRVGLYTGEISTTRALDE DSPR RLLVLVKDHGEP+LTATATVLVSL
Sbjct: 610 ELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669
Query: 669 VEGSQAPKASSRASVGVA-PEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPTE 727
VE QAPKASSRA VG A E LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS PTE
Sbjct: 670 VESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTE 729
Query: 728 GACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCP 778
GA P KPTLVCSSAVGSWSYSQQRRQRVCSGE PK DLMAFSPSL P
Sbjct: 730 GARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP 780
>gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 807
Score = 1158 bits (2996), Expect = 0.0
Identities = 604/775 (77%), Positives = 659/775 (85%), Gaps = 1/775 (0%)
Query: 3 SRCSCLGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRL 62
SR LG + LLL LLLLAAWEVGSGQLHYS+ EEA+HGTFVGR+AQDLGLELAELV RL
Sbjct: 4 SRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELVPRL 63
Query: 63 FRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEV 122
FRVASK H DLLEVNLQNGILFVNSRIDREELC S ECSIHLE+I DRPLQVFHV+V+V
Sbjct: 64 FRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVEVKV 123
Query: 123 KDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDII 182
KDINDNPP F EQ + IPESRLL+SRFP+EGA+DAD+G NALLTY LSP++YF LD+
Sbjct: 124 KDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSLDVE 183
Query: 183 NKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFD 242
+ K L LRK LDREE P+L LLLTATDGGKPE G+V LLI VLD NDNAP+FD
Sbjct: 184 ASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAPLFD 243
Query: 243 RPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIK 302
+ VY V + E N TLV LNASD+DEG+N E+++SF S + I+ KF ++ +GEI+
Sbjct: 244 QAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSGEIR 303
Query: 303 VNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDA 362
+ D +D+E++ +YEI V DKG+PPM HC VLV++LD NDN+PE+ VTSL LP++EDA
Sbjct: 304 LIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIREDA 363
Query: 363 QVGTVIALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYEL 422
+ TVIALI+VSD DSGANGQVTCSL PHVPFKLVST+KNYYSLVLDSALDRE +S YEL
Sbjct: 364 PLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSVYEL 423
Query: 423 VVTARDGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDAD 482
VVTARDGGSP LWATA VSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DAD
Sbjct: 424 VVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDAD 483
Query: 483 AQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVP 542
AQENALVSYSLVERR+GER+LS+YVSVHAESGKVYALQPLDHEELELLQFQVSARD GVP
Sbjct: 484 AQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVP 543
Query: 543 PLGSNLTLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGY 602
PLGSN+TLQVFVLDENDNAPALLA G GAVSELV R V AGHVVAKVRAVDADSGY
Sbjct: 544 PLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDADSGY 603
Query: 603 NAWLSYELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATA 662
NAWLSYELQ AA GARIPFRVGLYTGEISTTR LDE D R RLLVLVKDHGEP+LTATA
Sbjct: 604 NAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALTATA 663
Query: 663 TVLVSLVEGSQAPKASSRASVGVA-PEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRC 721
TVLVSLVE QAPKASSRASVGVA PE ALVDVNVYLIIAICAVSSLLVLTLLLYTALRC
Sbjct: 664 TVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRC 723
Query: 722 SAAPTEGACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPP 776
S PTEGA P KPTLVCSSA+GSWS SQQRRQRVCS EG PK DLMAFSP L P
Sbjct: 724 SVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSP 778
>gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens]
Length = 950
Score = 1158 bits (2996), Expect = 0.0
Identities = 604/775 (77%), Positives = 659/775 (85%), Gaps = 1/775 (0%)
Query: 3 SRCSCLGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRL 62
SR LG + LLL LLLLAAWEVGSGQLHYS+ EEA+HGTFVGR+AQDLGLELAELV RL
Sbjct: 4 SRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELVPRL 63
Query: 63 FRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEV 122
FRVASK H DLLEVNLQNGILFVNSRIDREELC S ECSIHLE+I DRPLQVFHV+V+V
Sbjct: 64 FRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVEVKV 123
Query: 123 KDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDII 182
KDINDNPP F EQ + IPESRLL+SRFP+EGA+DAD+G NALLTY LSP++YF LD+
Sbjct: 124 KDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSLDVE 183
Query: 183 NKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFD 242
+ K L LRK LDREE P+L LLLTATDGGKPE G+V LLI VLD NDNAP+FD
Sbjct: 184 ASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAPLFD 243
Query: 243 RPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIK 302
+ VY V + E N TLV LNASD+DEG+N E+++SF S + I+ KF ++ +GEI+
Sbjct: 244 QAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSGEIR 303
Query: 303 VNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDA 362
+ D +D+E++ +YEI V DKG+PPM HC VLV++LD NDN+PE+ VTSL LP++EDA
Sbjct: 304 LIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIREDA 363
Query: 363 QVGTVIALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYEL 422
+ TVIALI+VSD DSGANGQVTCSL PHVPFKLVST+KNYYSLVLDSALDRE +S YEL
Sbjct: 364 PLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSVYEL 423
Query: 423 VVTARDGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDAD 482
VVTARDGGSP LWATA VSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DAD
Sbjct: 424 VVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDAD 483
Query: 483 AQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVP 542
AQENALVSYSLVERR+GER+LS+YVSVHAESGKVYALQPLDHEELELLQFQVSARD GVP
Sbjct: 484 AQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVP 543
Query: 543 PLGSNLTLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGY 602
PLGSN+TLQVFVLDENDNAPALLA G GAVSELV R V AGHVVAKVRAVDADSGY
Sbjct: 544 PLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDADSGY 603
Query: 603 NAWLSYELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATA 662
NAWLSYELQ AA GARIPFRVGLYTGEISTTR LDE D R RLLVLVKDHGEP+LTATA
Sbjct: 604 NAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALTATA 663
Query: 663 TVLVSLVEGSQAPKASSRASVGVA-PEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRC 721
TVLVSLVE QAPKASSRASVGVA PE ALVDVNVYLIIAICAVSSLLVLTLLLYTALRC
Sbjct: 664 TVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRC 723
Query: 722 SAAPTEGACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPP 776
S PTEGA P KPTLVCSSA+GSWS SQQRRQRVCS EG PK DLMAFSP L P
Sbjct: 724 SVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSP 778
>gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo
sapiens]
Length = 685
Score = 1053 bits (2724), Expect = 0.0
Identities = 533/533 (100%), Positives = 533/533 (100%)
Query: 1 MVSRCSCLGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQ 60
MVSRCSCLGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQ
Sbjct: 1 MVSRCSCLGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQ 60
Query: 61 RLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDV 120
RLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDV
Sbjct: 61 RLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDV 120
Query: 121 EVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLD 180
EVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLD
Sbjct: 121 EVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLD 180
Query: 181 IINKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPI 240
IINKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPI
Sbjct: 181 IINKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPI 240
Query: 241 FDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGE 300
FDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGE
Sbjct: 241 FDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGE 300
Query: 301 IKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKE 360
IKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKE
Sbjct: 301 IKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKE 360
Query: 361 DAQVGTVIALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAY 420
DAQVGTVIALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAY
Sbjct: 361 DAQVGTVIALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAY 420
Query: 421 ELVVTARDGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWD 480
ELVVTARDGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWD
Sbjct: 421 ELVVTARDGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWD 480
Query: 481 ADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQ 533
ADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQ
Sbjct: 481 ADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQ 533
Score = 139 bits (350), Expect = 1e-32
Identities = 119/388 (30%), Positives = 177/388 (45%), Gaps = 28/388 (7%)
Query: 294 INERTGEIKVNDAIDFED----SNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEV 349
+N + G + VN ID E+ S IH++V P V H V VE+ D NDN P
Sbjct: 76 VNLQNGILFVNSRIDREELCGRSVECSIHLEVI-VDRPLQVFH--VDVEVKDINDNPPRF 132
Query: 350 IVTSLSLPVKEDAQVGTVIALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKN----YYS 405
VT L + E + + L SD D G N +T L+P+ F L K +
Sbjct: 133 SVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKDKFPV 192
Query: 406 LVLDSALDRERVSAYELVVTARDGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKE 465
LVL LDRE +L++TA DGG P + S+ + V D NDNAP F + Y V + E
Sbjct: 193 LVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEVKMYE 252
Query: 466 NNPPGCHIFTVSAWDADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHE 525
N + ++A D+D N + YS L ++ ++ +G++ +D E
Sbjct: 253 NQVNQTLVIRLNASDSDEGINKEMMYSFSS--LVPPTIRRKFWINERTGEIKVNDAIDFE 310
Query: 526 ELELLQFQVSARDGGVPPLGSNLTLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVV 585
+ + V D G PP+ + T+ V +LDENDN+P ++ + ++S V
Sbjct: 311 DSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVT-------SLSLPVKEDAQ 363
Query: 586 AGHVVAKVRAVDADSGYNAWLSYELQSAAVGARIPFR-VGLYTGEISTT--RALDETDSP 642
G V+A + D DSG N ++ L +PF+ V Y S ALD
Sbjct: 364 VGTVIALISVSDHDSGANGQVTCSLTP-----HVPFKLVSTYKNYYSLVLDSALDRERVS 418
Query: 643 RQRLLVLVKDHGEPSLTATATVLVSLVE 670
L+V +D G P L ATA+V V + +
Sbjct: 419 AYELVVTARDGGSPPLWATASVSVEVAD 446
Score = 136 bits (343), Expect = 7e-32
Identities = 111/394 (28%), Positives = 187/394 (47%), Gaps = 20/394 (5%)
Query: 231 VLDANDNAPIFDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSS---LVPPT 287
V D NDN P F ++ + E+++ + ASD+D G N + Y S V
Sbjct: 122 VKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDI 181
Query: 288 IRRKFWINERTGEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSP 347
I +K ++ + + +D E++ ++ + TD G P G ++L+ +LD NDN+P
Sbjct: 182 INKKD--KDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAP 239
Query: 348 EVIVTSLSLPVKEDAQVGTVIALISVSDHDSGANGQVTCSLTPHVPFKLVSTY---KNYY 404
+ + E+ T++ ++ SD D G N ++ S + VP + + +
Sbjct: 240 IFDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTG 299
Query: 405 SLVLDSALDRERVSAYELVVTARDGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVK 464
+ ++ A+D E + YE+ V D G+PP+ +V VE+ D NDN+P + ++ VK
Sbjct: 300 EIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVK 359
Query: 465 ENNPPGCHIFTVSAWDADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDH 524
E+ G I +S D D+ N V+ SL + + +S+Y + ++ + LD
Sbjct: 360 EDAQVGTVIALISVSDHDSGANGQVTCSLTPH-VPFKLVSTYKNYYS----LVLDSALDR 414
Query: 525 EELELLQFQVSARDGGVPPLGSNLTLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSV 584
E + + V+ARDGG PPL + ++ V V D NDNAPA A + V +
Sbjct: 415 ERVSAYELVVTARDGGSPPLWATASVSVEVADVNDNAPAF-------AQSEYTVFVKENN 467
Query: 585 VAGHVVAKVRAVDADSGYNAWLSYELQSAAVGAR 618
G + V A DAD+ NA +SY L +G R
Sbjct: 468 PPGCHIFTVSAWDADAQENALVSYSLVERRLGER 501
Score = 91.7 bits (226), Expect = 3e-18
Identities = 81/270 (30%), Positives = 121/270 (44%), Gaps = 16/270 (5%)
Query: 440 VSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSLVERRLG 499
V VEV D+NDN P F+ +E + + E+ A DAD ENAL++Y L
Sbjct: 118 VDVEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYF 177
Query: 500 ERSLSSYVSVHAESGKVYALQPL-DHEELELLQFQVSARDGGVPPLGSNLTLQVFVLDEN 558
+ + + V L+ L D EE L+ ++A DGG P +++L + VLD N
Sbjct: 178 VLDIIN--KKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDAN 235
Query: 559 DNAPALLASPAGSAGGAVSELVL-RSVVAGHVVAKVRAVDADSGYNAWLSYELQSAAVGA 617
DNAP V E+ + + V +V ++ A D+D G N + Y S
Sbjct: 236 DNAPIF--------DRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPT 287
Query: 618 -RIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSLVEGSQAPK 676
R F + TGEI A+D DS + V V D G P + TVLV L++ +
Sbjct: 288 IRRKFWINERTGEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSP 347
Query: 677 ASSRASVGVAPEVALVDVNVYLIIAICAVS 706
S+ + + D V +IA+ +VS
Sbjct: 348 EVIVTSLSLPVK---EDAQVGTVIALISVS 374
>gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo
sapiens]
Length = 686
Score = 795 bits (2054), Expect = 0.0
Identities = 408/526 (77%), Positives = 449/526 (85%)
Query: 8 LGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVAS 67
LG QCLLL LLLLAAW+VGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLFR+AS
Sbjct: 9 LGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMAS 68
Query: 68 KRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDIND 127
K DLLEVNLQNGILFVNSRIDREELCGRS ECSIHLEVIVDRPLQVFHVDVEV+DIND
Sbjct: 69 KDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDIND 128
Query: 128 NPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDK 187
NPP F V EQ++ I ESRL DS FPLEGASDADVG N++LTYKLS +EYF LD+ D
Sbjct: 129 NPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDD 188
Query: 188 DKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYE 247
+K L+L+K LDREE P L LTATDGGKPE TG+V LL+ VLD NDNAP F++ YE
Sbjct: 189 NKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248
Query: 248 VKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAI 307
V+++EN N T VIRLNASD DEG N + YSF+SLV + F I+ TGEI + +
Sbjct: 249 VRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNL 308
Query: 308 DFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTV 367
DFE N Y+I +D TDKG+PPM GHCTVLV +LD+NDN PE+ +TSLSLPV+EDAQ GTV
Sbjct: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368
Query: 368 IALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTAR 427
IALISV+D DSGANGQV CSLTPHVPFKLVST+KNYYSLVLDSALDRE VSAYELVVTAR
Sbjct: 369 IALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTAR 428
Query: 428 DGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENA 487
DGGSP LWATAS+SVEVAD+NDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQENA
Sbjct: 429 DGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488
Query: 488 LVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQ 533
LVSYSLVERR+GER+LSSY+SVHAESGKVYALQPLDHEELELLQFQ
Sbjct: 489 LVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQ 534
Score = 160 bits (406), Expect = 4e-39
Identities = 119/395 (30%), Positives = 192/395 (48%), Gaps = 22/395 (5%)
Query: 231 VLDANDNAPIFDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSS--LVPPTI 288
V D NDN P+F V +YE+++ ++ ASD+D G N + Y SS +
Sbjct: 123 VRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDV 182
Query: 289 RRKFWINERTGEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPE 348
+ N++ G + + ++D E++ + + + TD G P + G +LV +LD NDN+P
Sbjct: 183 KINSDDNKQIG-LLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPT 241
Query: 349 VIVTSLSLPVKEDAQVGTVIALISVSDHDSGANGQVTCSLTPHVPFKLVSTY---KNYYS 405
+ + + E+A GT + ++ SD D GANG ++ S V ++ + +N
Sbjct: 242 FEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGE 301
Query: 406 LVLDSALDRERVSAYELVVTARDGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKE 465
+V+ LD E+ + Y++++ A D G PP+ +V V + D NDN P A + ++ V+E
Sbjct: 302 IVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVRE 361
Query: 466 NNPPGCHIFTVSAWDADAQENALVSYSLVERRLGE--RSLSSYVSVHAESGKVYALQPLD 523
+ G I +S D D+ N V+ SL + + +Y S+ +S LD
Sbjct: 362 DAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSA-------LD 414
Query: 524 HEELELLQFQVSARDGGVPPLGSNLTLQVFVLDENDNAPALLASPAGSAGGAVSELVLRS 583
E + + V+ARDGG P L + +L V V D NDNAPA A + V +
Sbjct: 415 RESVSAYELVVTARDGGSPSLWATASLSVEVADMNDNAPAF-------AQPEYTVFVKEN 467
Query: 584 VVAGHVVAKVRAVDADSGYNAWLSYELQSAAVGAR 618
G + V A DAD+ NA +SY L VG R
Sbjct: 468 NPPGCHIFTVSARDADAQENALVSYSLVERRVGER 502
Score = 157 bits (397), Expect = 4e-38
Identities = 126/388 (32%), Positives = 181/388 (46%), Gaps = 28/388 (7%)
Query: 294 INERTGEIKVNDAIDFED----SNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEV 349
+N + G + VN ID E+ S IH++V P V H V VE+ D NDN P
Sbjct: 77 VNLQNGILFVNSRIDREELCGRSAECSIHLEVI-VDRPLQVFH--VDVEVRDINDNPPLF 133
Query: 350 IVTSLSLPVKEDAQVGTVIALISVSDHDSGANGQVTCSLTPHVPF----KLVSTYKNYYS 405
V + + E +V L SD D G+N +T L+ F K+ S
Sbjct: 134 PVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIG 193
Query: 406 LVLDSALDRERVSAYELVVTARDGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKE 465
L+L +LDRE A+ L +TA DGG P L T + V V DVNDNAP F QSEY V + E
Sbjct: 194 LLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFE 253
Query: 466 NNPPGCHIFTVSAWDADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHE 525
N G + ++A D D N +SYS L + + S+ +G++ LD E
Sbjct: 254 NADNGTTVIRLNASDRDEGANGAISYSF--NSLVAAMVIDHFSIDRNTGEIVIRGNLDFE 311
Query: 526 ELELLQFQVSARDGGVPPLGSNLTLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVV 585
+ L + + A D G PP+ + T+ V +LD+NDN P + + ++S V
Sbjct: 312 QENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALT-------SLSLPVREDAQ 364
Query: 586 AGHVVAKVRAVDADSGYNAWLSYELQSAAVGARIPFR-VGLYTGEISTT--RALDETDSP 642
G V+A + D DSG N ++ L +PF+ V + S ALD
Sbjct: 365 FGTVIALISVNDLDSGANGQVNCSLT-----PHVPFKLVSTFKNYYSLVLDSALDRESVS 419
Query: 643 RQRLLVLVKDHGEPSLTATATVLVSLVE 670
L+V +D G PSL ATA++ V + +
Sbjct: 420 AYELVVTARDGGSPSLWATASLSVEVAD 447
>gi|14165402 protocadherin alpha 1 isoform 3 precursor [Homo
sapiens]
Length = 686
Score = 775 bits (2001), Expect = 0.0
Identities = 395/531 (74%), Positives = 447/531 (84%)
Query: 3 SRCSCLGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRL 62
SR LG + LLL LLLLAAWEVGSGQLHYS+ EEA+HGTFVGR+AQDLGLELAELV RL
Sbjct: 4 SRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELVPRL 63
Query: 63 FRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEV 122
FRVASK H DLLEVNLQNGILFVNSRIDREELC S ECSIHLE+I DRPLQVFHV+V+V
Sbjct: 64 FRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVEVKV 123
Query: 123 KDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDII 182
KDINDNPP F EQ + IPESRLL+SRFP+EGA+DAD+G NALLTY LSP++YF LD+
Sbjct: 124 KDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSLDVE 183
Query: 183 NKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFD 242
+ K L LRK LDREE P+L LLLTATDGGKPE G+V LLI VLD NDNAP+FD
Sbjct: 184 ASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAPLFD 243
Query: 243 RPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIK 302
+ VY V + E N TLV LNASD+DEG+N E+++SF S + I+ KF ++ +GEI+
Sbjct: 244 QAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSGEIR 303
Query: 303 VNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDA 362
+ D +D+E++ +YEI V DKG+PPM HC VLV++LD NDN+PE+ VTSL LP++EDA
Sbjct: 304 LIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIREDA 363
Query: 363 QVGTVIALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYEL 422
+ TVIALI+VSD DSGANGQVTCSL PHVPFKLVST+KNYYSLVLDSALDRE +S YEL
Sbjct: 364 PLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSVYEL 423
Query: 423 VVTARDGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDAD 482
VVTARDGGSP LWATA VSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DAD
Sbjct: 424 VVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDAD 483
Query: 483 AQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQ 533
AQENALVSYSLVERR+GER+LS+YVSVHAESGKVYALQPLDHEELELLQFQ
Sbjct: 484 AQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQ 534
Score = 144 bits (364), Expect = 3e-34
Identities = 125/391 (31%), Positives = 177/391 (45%), Gaps = 34/391 (8%)
Query: 294 INERTGEIKVNDAIDFED----SNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEV 349
+N + G + VN ID E+ S IH+++ P V H V V+ D NDN P
Sbjct: 77 VNLQNGILFVNSRIDREELCQWSAECSIHLELI-ADRPLQVFHVEVKVK--DINDNPPVF 133
Query: 350 IVTSLSLPVKEDAQVGTVIALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYS---- 405
+ + E + + + +D D GAN +T +L+P F L + S
Sbjct: 134 RGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSLDVEASDELSKSLW 193
Query: 406 LVLDSALDRERVSAYELVVTARDGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKE 465
L L LDRE L++TA DGG P L T + + V DVNDNAP F Q+ Y V + E
Sbjct: 194 LELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAPLFDQAVYRVHLLE 253
Query: 466 NNPPGCHIFTVSAWDADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHE 525
G + T++A DAD N V +S R + V + SG++ + LD+E
Sbjct: 254 TTANGTLVTTLNASDADEGVNGEVVFSFDSGI--SRDIQEKFKVDSSSGEIRLIDKLDYE 311
Query: 526 ELELLQFQVSARDGGVPPLGSNLTLQVFVLDENDNAPALLASPAGSAGGAVSELVL---R 582
E + + QV A D G PP+ ++ + V VLD NDNAP L AV+ L L
Sbjct: 312 ETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPEL----------AVTSLYLPIRE 361
Query: 583 SVVAGHVVAKVRAVDADSGYNAWLSYELQSAAVGARIPFR-VGLYTGEISTT--RALDET 639
V+A + D DSG N ++ L +PF+ V + S ALD
Sbjct: 362 DAPLSTVIALITVSDRDSGANGQVTCSLM-----PHVPFKLVSTFKNYYSLVLDSALDRE 416
Query: 640 DSPRQRLLVLVKDHGEPSLTATATVLVSLVE 670
L+V +D G PSL ATA V V + +
Sbjct: 417 SLSVYELVVTARDGGSPSLWATARVSVEVAD 447
Score = 142 bits (359), Expect = 1e-33
Identities = 123/432 (28%), Positives = 188/432 (43%), Gaps = 34/432 (7%)
Query: 229 ILVLDANDNAPIFDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSL----- 283
+ V D NDN P+F + + E+++ + A+D+D G N + Y+ S
Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180
Query: 284 ---VPPTIRRKFWINERTGEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELL 340
+ + W+ R +D E++ + + TD G P + G +L+ +L
Sbjct: 181 DVEASDELSKSLWLELRK-------YLDREETPELHLLLTATDGGKPELQGTVELLITVL 233
Query: 341 DENDNSPEVIVTSLSLPVKEDAQVGTVIALISVSDHDSGANGQVTCSLTPHVPFKLVSTY 400
D NDN+P + + E GT++ ++ SD D G NG+V S + + +
Sbjct: 234 DVNDNAPLFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKF 293
Query: 401 KNYYS---LVLDSALDRERVSAYELVVTARDGGSPPLWATASVSVEVADVNDNAPAFAQS 457
K S + L LD E +YE+ V A D GSPP+ V V+V DVNDNAP A +
Sbjct: 294 KVDSSSGEIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVT 353
Query: 458 EYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSLVERRLGE--RSLSSYVSVHAESGK 515
+ ++E+ P I ++ D D+ N V+ SL+ + + +Y S+ +S
Sbjct: 354 SLYLPIREDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSA- 412
Query: 516 VYALQPLDHEELELLQFQVSARDGGVPPLGSNLTLQVFVLDENDNAPALLASPAGSAGGA 575
LD E L + + V+ARDGG P L + + V V D NDNAPA A
Sbjct: 413 ------LDRESLSVYELVVTARDGGSPSLWATARVSVEVADVNDNAPAF-------AQPE 459
Query: 576 VSELVLRSVVAGHVVAKVRAVDADSGYNAWLSYELQSAAVGARIPFRVGLYTGEISTTRA 635
+ V + G + V A DAD+ NA +SY L VG R E A
Sbjct: 460 YTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYA 519
Query: 636 LDETDSPRQRLL 647
L D LL
Sbjct: 520 LQPLDHEELELL 531
>gi|14277677 protocadherin gamma subfamily C, 3 isoform 2 precursor
[Homo sapiens]
Length = 863
Score = 595 bits (1533), Expect = e-170
Identities = 314/697 (45%), Positives = 447/697 (64%), Gaps = 7/697 (1%)
Query: 17 LLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASKRHGDLLEV 76
LLLL A S +HY + EE G VG + +LGL+L L R FRV S EV
Sbjct: 20 LLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFEV 79
Query: 77 NLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDNPPRFSVTE 136
N + G +FVN R+DREELCG C++ LE++V+ PL++F V+V ++DINDN P F E
Sbjct: 80 NRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQE 139
Query: 137 QKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKDKFPVLVLR 196
KL I E+ +RFPLE A D DVG N+L TY+LS NEYF L + ++D K+ LVL
Sbjct: 140 MKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVLE 199
Query: 197 KLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEVKMYENQVN 256
+ LDRE P L+L+LTA DGG P + S+ + I VLDANDNAP+F++ +Y ++ E+ +
Sbjct: 200 RALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAPS 259
Query: 257 QTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAIDFEDSNTYE 316
T V+++ A+D DEG N E++YSF S +R+ F ++ TG + + +DFED+ +E
Sbjct: 260 GTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLHE 319
Query: 317 IHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVIALISVSDH 376
I++ DKG P HC VLVE++D NDN+PE+ VTS+ PV EDA +GTVIAL+SV+D
Sbjct: 320 IYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTDL 379
Query: 377 DSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARDGGSPPLWA 436
D+G NG VTC + P +PF L S+ KNY++L + LDRE V Y L +TARD G+P L A
Sbjct: 380 DAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLSA 439
Query: 437 TASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSLVER 496
V V+V+D+NDN P +QS Y V+++ENN PG I +S WD DA +NA +S+ L+E+
Sbjct: 440 LTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLEQ 499
Query: 497 RLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNLTLQVFVLD 556
+ Y +++ ++G V +L PLD+E+ + DGG P L +N+++ +FV D
Sbjct: 500 GAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVTD 559
Query: 557 ENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSYELQSAAVG 616
NDNAP +L GG+ E++ R AGH+V++V DAD+G+NAWLSY L +
Sbjct: 560 RNDNAPQVLYP---RPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSP-- 614
Query: 617 ARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSLVEGSQAPK 676
+ F +GL+TG+IST R + +TDSPRQ L VL+KD+GEPSL+ TAT+ VS+ E S P+
Sbjct: 615 NQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDS--PE 672
Query: 677 ASSRASVGVAPEVALVDVNVYLIIAICAVSSLLVLTL 713
A + G AP ++ YL++++ VS V+T+
Sbjct: 673 ARAEFPSGSAPREQKKNLTFYLLLSLILVSVGFVVTV 709
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,644,753
Number of Sequences: 37866
Number of extensions: 1412685
Number of successful extensions: 10110
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 188
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 3198
Number of HSP's gapped (non-prelim): 693
length of query: 844
length of database: 18,247,518
effective HSP length: 111
effective length of query: 733
effective length of database: 14,044,392
effective search space: 10294539336
effective search space used: 10294539336
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.