Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 9966885
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|9966885 tumor endothelial marker 1 precursor [Homo sapiens]
(757 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|9966885 tumor endothelial marker 1 precursor [Homo sapiens] 1610 0.0
gi|4507483 thrombomodulin precursor [Homo sapiens] 213 7e-55
gi|88758613 CD93 antigen precursor [Homo sapiens] 201 3e-51
gi|28269707 C-type lectin domain family 14, member A [Homo sapiens] 127 3e-29
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 97 7e-20
gi|34734064 fibulin 1 isoform B precursor [Homo sapiens] 92 1e-18
gi|34734068 fibulin 1 isoform A precursor [Homo sapiens] 92 1e-18
gi|34734066 fibulin 1 isoform D [Homo sapiens] 92 1e-18
gi|34734062 fibulin 1 isoform C precursor [Homo sapiens] 92 1e-18
gi|51873055 fibulin 2 isoform b precursor [Homo sapiens] 89 2e-17
gi|51873053 fibulin 2 isoform a precursor [Homo sapiens] 89 2e-17
gi|114431244 von Willebrand factor C and EGF domains [Homo sapiens] 86 1e-16
gi|10190748 CEGP1 protein [Homo sapiens] 82 1e-15
gi|62548862 matrilin 2 isoform b precursor [Homo sapiens] 82 2e-15
gi|62548860 matrilin 2 isoform a precursor [Homo sapiens] 82 2e-15
gi|31377568 signal peptide, CUB domain, EGF-like 3 [Homo sapiens] 82 2e-15
gi|19743803 fibulin 5 precursor [Homo sapiens] 81 3e-15
gi|239751395 PREDICTED: hypothetical protein, partial [Homo sapi... 81 3e-15
gi|239745904 PREDICTED: hypothetical protein, partial [Homo sapi... 81 3e-15
gi|120587029 signal peptide, CUB domain, EGF-like 1 [Homo sapiens] 80 5e-15
gi|4557617 growth arrest-specific 6 isoform 1 precursor [Homo sa... 79 1e-14
gi|13699830 matrilin 4 isoform 1 precursor [Homo sapiens] 79 2e-14
gi|126012573 low density lipoprotein-related protein 2 [Homo sap... 79 2e-14
gi|190343004 EGF-containing fibulin-like extracellular matrix pr... 77 8e-14
gi|66346695 fibrillin 2 precursor [Homo sapiens] 76 1e-13
gi|56237021 fibrillin 3 precursor [Homo sapiens] 76 1e-13
gi|169211436 PREDICTED: hypothetical protein [Homo sapiens] 75 2e-13
gi|86788132 EGF-containing fibulin-like extracellular matrix pro... 74 4e-13
gi|86788015 EGF-containing fibulin-like extracellular matrix pro... 74 4e-13
gi|9665262 EGF-containing fibulin-like extracellular matrix prot... 74 4e-13
>gi|9966885 tumor endothelial marker 1 precursor [Homo sapiens]
Length = 757
Score = 1610 bits (4169), Expect = 0.0
Identities = 757/757 (100%), Positives = 757/757 (100%)
Query: 1 MLLRLLLAWAAAGPTLGQDPWAAEPRAACGPSSCYALFPRRRTFLEAWRACRELGGDLAT 60
MLLRLLLAWAAAGPTLGQDPWAAEPRAACGPSSCYALFPRRRTFLEAWRACRELGGDLAT
Sbjct: 1 MLLRLLLAWAAAGPTLGQDPWAAEPRAACGPSSCYALFPRRRTFLEAWRACRELGGDLAT 60
Query: 61 PRTPEEAQRVDSLVGAGPASRLLWIGLQRQARQCQLQRPLRGFTWTTGDQDTAFTNWAQP 120
PRTPEEAQRVDSLVGAGPASRLLWIGLQRQARQCQLQRPLRGFTWTTGDQDTAFTNWAQP
Sbjct: 61 PRTPEEAQRVDSLVGAGPASRLLWIGLQRQARQCQLQRPLRGFTWTTGDQDTAFTNWAQP 120
Query: 121 ASGGPCPAQRCVALEASGEHRWLEGSCTLAVDGYLCQFGFEGACPALQDEAGQAGPAVYT 180
ASGGPCPAQRCVALEASGEHRWLEGSCTLAVDGYLCQFGFEGACPALQDEAGQAGPAVYT
Sbjct: 121 ASGGPCPAQRCVALEASGEHRWLEGSCTLAVDGYLCQFGFEGACPALQDEAGQAGPAVYT 180
Query: 181 TPFHLVSTEFEWLPFGSVAAVQCQAGRGASLLCVKQPEGGVGWSRAGPLCLGTGCSPDNG 240
TPFHLVSTEFEWLPFGSVAAVQCQAGRGASLLCVKQPEGGVGWSRAGPLCLGTGCSPDNG
Sbjct: 181 TPFHLVSTEFEWLPFGSVAAVQCQAGRGASLLCVKQPEGGVGWSRAGPLCLGTGCSPDNG 240
Query: 241 GCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGYSCHCRLGF 300
GCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGYSCHCRLGF
Sbjct: 241 GCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGYSCHCRLGF 300
Query: 301 RPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISCSPAGAMGAQA 360
RPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISCSPAGAMGAQA
Sbjct: 301 RPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISCSPAGAMGAQA 360
Query: 361 SQDLGDELLDDGEDEEDEDEAWKAFNGGWTEMPGILWMEPTQPPDFALAYRPSFPEDREP 420
SQDLGDELLDDGEDEEDEDEAWKAFNGGWTEMPGILWMEPTQPPDFALAYRPSFPEDREP
Sbjct: 361 SQDLGDELLDDGEDEEDEDEAWKAFNGGWTEMPGILWMEPTQPPDFALAYRPSFPEDREP 420
Query: 421 QIPYPEPTWPPPLSAPRVPYHSSVLSVTRPVVVSATHPTLPSAHQPPVIPATHPALSRDH 480
QIPYPEPTWPPPLSAPRVPYHSSVLSVTRPVVVSATHPTLPSAHQPPVIPATHPALSRDH
Sbjct: 421 QIPYPEPTWPPPLSAPRVPYHSSVLSVTRPVVVSATHPTLPSAHQPPVIPATHPALSRDH 480
Query: 481 QIPVIAANYPDLPSAYQPGILSVSHSAQPPAHQPPMISTKYPELFPAHQSPMFPDTRVAG 540
QIPVIAANYPDLPSAYQPGILSVSHSAQPPAHQPPMISTKYPELFPAHQSPMFPDTRVAG
Sbjct: 481 QIPVIAANYPDLPSAYQPGILSVSHSAQPPAHQPPMISTKYPELFPAHQSPMFPDTRVAG 540
Query: 541 TQTTTHLPGIPPNHAPLVTTLGAQLPPQAPDALVLRTQATQLPIIPTAQPSLTTTSRSPV 600
TQTTTHLPGIPPNHAPLVTTLGAQLPPQAPDALVLRTQATQLPIIPTAQPSLTTTSRSPV
Sbjct: 541 TQTTTHLPGIPPNHAPLVTTLGAQLPPQAPDALVLRTQATQLPIIPTAQPSLTTTSRSPV 600
Query: 601 SPAHQISVPAATQPAALPTLLPSQSPTNQTSPISPTHPHSKAPQIPREDGPSPKLALWLP 660
SPAHQISVPAATQPAALPTLLPSQSPTNQTSPISPTHPHSKAPQIPREDGPSPKLALWLP
Sbjct: 601 SPAHQISVPAATQPAALPTLLPSQSPTNQTSPISPTHPHSKAPQIPREDGPSPKLALWLP 660
Query: 661 SPAPTAAPTALGEAGLAEHSQRDDRWLLVALLVPTCVFLVVLLALGIVYCTRCGPHAPNK 720
SPAPTAAPTALGEAGLAEHSQRDDRWLLVALLVPTCVFLVVLLALGIVYCTRCGPHAPNK
Sbjct: 661 SPAPTAAPTALGEAGLAEHSQRDDRWLLVALLVPTCVFLVVLLALGIVYCTRCGPHAPNK 720
Query: 721 RITDCYRWVIHAGSKSPTEPMPPRGSLTGVQTCRTSV 757
RITDCYRWVIHAGSKSPTEPMPPRGSLTGVQTCRTSV
Sbjct: 721 RITDCYRWVIHAGSKSPTEPMPPRGSLTGVQTCRTSV 757
>gi|4507483 thrombomodulin precursor [Homo sapiens]
Length = 575
Score = 213 bits (541), Expect = 7e-55
Identities = 147/375 (39%), Positives = 184/375 (49%), Gaps = 34/375 (9%)
Query: 2 LLRLLLAWAAAGPTLGQDPWAAEPR---AACGPSSCYALFPRRRTFLEAWRACRELGGDL 58
+L +L+ A A LG P AEP+ + C C+AL+P TFL A + C L G L
Sbjct: 1 MLGVLVLGALALAGLGF-PAPAEPQPGGSQCVEHDCFALYPGPATFLNASQICDGLRGHL 59
Query: 59 ATPRTPEEAQRVDSLVGA--GPASRLLWIGLQRQARQCQLQR--PLRGFTWTTGDQDTAF 114
T R+ A + L+ G R LWIGLQ +R PLRGF W TGD +T++
Sbjct: 60 MTVRSSVAADVISLLLNGDGGVGRRRLWIGLQLPPGCGDPKRLGPLRGFQWVTGDNNTSY 119
Query: 115 TNWAQ-PASGGPCPAQRCVALEAS-----GEHRWLEGSCTLAVDGYLCQFGFEGACPALQ 168
+ WA+ +G P CVA+ A+ E W E C + DG+LC+F F C L
Sbjct: 120 SRWARLDLNGAPLCGPLCVAVSAAEATVPSEPIWEEQQCEVKADGFLCEFHFPATCRPLA 179
Query: 169 DEAGQAGPAV---YTTPFHLVSTEFEWLPFGSVAAVQCQAGRGASLLCVKQPEGGVG-WS 224
E G A AV Y TPF +F+ LP GS AAV A G L+C P G W+
Sbjct: 180 VEPGAAAAAVSITYGTPFAARGADFQALPVGSSAAV---APLGLQLMCTAPPGAVQGHWA 236
Query: 225 RAGPLCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQC 284
R P CS +NGGCEH C + G C+C G L ADGRSC Q+ C C
Sbjct: 237 REAP--GAWDCSVENGGCEHAC-NAIPGAPRCQCPAGAALQADGRSCTASATQS-CNDLC 292
Query: 285 E------PGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQI-AGVCQQMCVNYVGGFECYC 337
E P P YSC C G+R A D HRC D D+C + C Q CVN GGFEC+C
Sbjct: 293 EHFCVPNPDQPGSYSCMCETGYRLAADQ-HRCEDVDDCILEPSPCPQRCVNTQGGFECHC 351
Query: 338 SEGHELEADGISCSP 352
++L DG P
Sbjct: 352 YPNYDL-VDGECVEP 365
>gi|88758613 CD93 antigen precursor [Homo sapiens]
Length = 652
Score = 201 bits (510), Expect = 3e-51
Identities = 137/401 (34%), Positives = 189/401 (47%), Gaps = 54/401 (13%)
Query: 1 MLLRLLLAWAAAGPTLGQDPWAAEPRAACGPSSCYALFPRRRTFLEAWRACRELGGDLAT 60
+LL LLL G G D A C ++CY + + EA C + GG+LAT
Sbjct: 7 LLLLLLLLLTQPGAGTGADTEAV----VCVGTACYTAHSGKLSAAEAQNHCNQNGGNLAT 62
Query: 61 PRTPEEAQRVDSLVG------AGPASRL--LWIGLQRQARQC-QLQRPLRGFTWTTGDQD 111
++ EEAQ V ++ A +R+ WIGLQR+ +C PL+GF+W G +D
Sbjct: 63 VKSKEEAQHVQRVLAQLLRREAALTARMSKFWIGLQREKGKCLDPSLPLKGFSWVGGGED 122
Query: 112 TAFTNWAQPASGGPCPAQRCVALEA--------SGEHRWLEGSCTLA------VDGYLCQ 157
T ++NW + C ++RCV+L S +W EG C ++G++C+
Sbjct: 123 TPYSNWHKELRNS-CISKRCVSLLLDLSQPLLPSRLPKWSEGPCGSPGSPGSNIEGFVCK 181
Query: 158 FGFEGACPALQDEAGQAGPAVYTTPFHLVSTEFEWLPFGSVAAVQCQAG-----RGASLL 212
F F+G C L G G YTTPF S+ E +PF S A V C G + L
Sbjct: 182 FSFKGMCRPLA--LGGPGQVTYTTPFQTTSSSLEAVPFASAANVACGEGDKDETQSHYFL 239
Query: 213 CVKQPEGGVGWSRAGPLCLGT--GCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRS 270
C ++ W +GPLC+ GC+ +NGGC +C E DG C C GFRL D +
Sbjct: 240 CKEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVT 299
Query: 271 C--EDPCAQAPCEQQCE-PGGPQG--YSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQM 325
C +PC+ +PC GP G Y+C C G++ + CVD DECQ C Q
Sbjct: 300 CASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQ-LDSSQLDCVDVDECQ-DSPCAQE 357
Query: 326 CVNYVGGFECYCSEGHELEADGISCSPAGAMGAQASQDLGD 366
CVN GGF C C G+E G G A QD+ +
Sbjct: 358 CVNTPGGFRCECWVGYE----------PGGPGEGACQDVDE 388
>gi|28269707 C-type lectin domain family 14, member A [Homo sapiens]
Length = 490
Score = 127 bits (320), Expect = 3e-29
Identities = 93/285 (32%), Positives = 127/285 (44%), Gaps = 23/285 (8%)
Query: 5 LLLAWAAAGPTLGQDPWAAEPRAACGPS-SCYALFPRRRTFLEAWRACRELGGDLATPRT 63
L L W A P G RA C S +CY+L A AC GG L+T R
Sbjct: 7 LCLLWQALWPGPGGGEHPTADRAGCSASGACYSLHHATMKRQAAEEACILRGGALSTVRA 66
Query: 64 PEEAQRVDSLVGAGPA------SRLLWIGLQRQARQCQLQR-PLRGFTWTTGDQ---DTA 113
E + V +L+ AGP L W+ L+R+ C L+ PLRGF+W + D ++
Sbjct: 67 GAELRAVLALLRAGPGPGGGSKDLLFWVALERRRSHCTLENEPLRGFSWLSSDPGGLESD 126
Query: 114 FTNWAQPASGGPCPAQRCVALEASGEHR---WLEGSCTLAVDGYLCQFGFEGACPALQDE 170
W + C A+RC L+A+G W E C L +GYLC++ FE CPA
Sbjct: 127 TLQWVEEPQRS-CTARRCAVLQATGGVEPAGWKEMRCHLRANGYLCKYQFEVLCPA--PR 183
Query: 171 AGQAGPAVYTTPFHLVSTEFEWLPFGSVAAVQCQAGRGASLLCVKQPEGGVGWSR--AGP 228
G A Y PF L S ++ P G+ + C+ S+ C+ E G W +
Sbjct: 184 PGAASNLSYRAPFQLHSAALDFSPPGTEVSALCRGQLPISVTCIAD-EIGARWDKLSGDV 242
Query: 229 LCLGTGCSPDNGGCEH--ECVEEVDGHVSCRCTEGFRLAADGRSC 271
LC G G C C++++ G +C C GF L DGRSC
Sbjct: 243 LCPCPGRYLRAGKCAELPNCLDDLGG-FACECATGFELGKDGRSC 286
Score = 37.7 bits (86), Expect = 0.040
Identities = 17/38 (44%), Positives = 24/38 (63%), Gaps = 2/38 (5%)
Query: 319 AGVCQQM--CVNYVGGFECYCSEGHELEADGISCSPAG 354
AG C ++ C++ +GGF C C+ G EL DG SC +G
Sbjct: 253 AGKCAELPNCLDDLGGFACECATGFELGKDGRSCVTSG 290
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 96.7 bits (239), Expect = 7e-20
Identities = 49/121 (40%), Positives = 60/121 (49%), Gaps = 5/121 (4%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSC--EDPCAQAPCEQQCEPGGPQGY 292
C +NGGC H C G + C C G+ L D R+C D CA +PC QQ P GY
Sbjct: 335 CEANNGGCSHGCSHTSAGPL-CTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGY 393
Query: 293 SCHCRLGFRPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGGFECYCSEGHELEADGISCS 351
C C G+R + D C D DEC + G C+ C N G F+C C G+ L D CS
Sbjct: 394 ECGCYAGYRLSADGCG-CEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCS 452
Query: 352 P 352
P
Sbjct: 453 P 453
Score = 87.0 bits (214), Expect = 6e-17
Identities = 51/129 (39%), Positives = 67/129 (51%), Gaps = 12/129 (9%)
Query: 230 CLG-TGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSC--EDPCA--QAPCEQQC 284
CL C+ NGGC+H CV+ C+C GF+L DGR C PCA C +C
Sbjct: 200 CLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRC 259
Query: 285 EPGGPQGYS-CHCRLGFRPAEDDPHRCVDTDECQIAGV--CQQMCVNYVGGFECYCSEGH 341
+ +G + C C +G++ A D C D DEC AG+ C C+N G F+C C G+
Sbjct: 260 QV--VRGLARCECHVGYQLAADG-KACEDVDEC-AAGLAQCAHGCLNTQGSFKCVCHAGY 315
Query: 342 ELEADGISC 350
EL ADG C
Sbjct: 316 ELGADGRQC 324
Score = 80.9 bits (198), Expect = 4e-15
Identities = 50/164 (30%), Positives = 64/164 (39%), Gaps = 49/164 (29%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPG--GPQG- 291
C+ NG C H C + V G C C G++LAADG++CED A QC G QG
Sbjct: 248 CANRNGSCMHRC-QVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGS 306
Query: 292 YSCHCRLGFRPAED---------------------------------------------D 306
+ C C G+ D D
Sbjct: 307 FKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTD 366
Query: 307 PHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
C+D D+C + CQQ+C N GG+EC C G+ L ADG C
Sbjct: 367 QRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGC 410
Score = 76.6 bits (187), Expect = 8e-14
Identities = 47/133 (35%), Positives = 57/133 (42%), Gaps = 7/133 (5%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCA--QAPCEQQCEPGGPQ 290
C NGGC+H CV G C C GFRL D R+C + CA C+ C
Sbjct: 165 CRTHNGGCQHRCVN-TPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTIT 223
Query: 291 GYSCHCRLGFRPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGGFECYCSEGHELEADGIS 349
+ C CR GF+ ED H CV C G C C G C C G++L ADG +
Sbjct: 224 RHRCQCRPGFQLQEDGRH-CVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKA 282
Query: 350 CSPAGAMGAQASQ 362
C A +Q
Sbjct: 283 CEDVDECAAGLAQ 295
Score = 53.9 bits (128), Expect = 5e-07
Identities = 34/98 (34%), Positives = 42/98 (42%), Gaps = 10/98 (10%)
Query: 257 RCTEGFRLAADGRSC-EDPCAQAPCEQ--QCEPGGPQGYSCHCRLGFRPAEDDPHRCVDT 313
RC G+ D C C+ + C +C PG Q CHC GF+ P D
Sbjct: 109 RCCRGWMQQPDEEGCLSAECSASLCFHGGRCVPGSAQ--PCHCPPGFQ----GPRCQYDV 162
Query: 314 DECQIA-GVCQQMCVNYVGGFECYCSEGHELEADGISC 350
DEC+ G CQ CVN G + C C G L D +C
Sbjct: 163 DECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTC 200
Score = 35.8 bits (81), Expect = 0.15
Identities = 68/264 (25%), Positives = 80/264 (30%), Gaps = 74/264 (28%)
Query: 120 PASGGPCPAQRCVALEASGEHRWLEGSCTLAVDGYLCQFGFEGACPALQDEAGQAGPAVY 179
P GP Q C L GSC A C GF G L G+ GP
Sbjct: 1208 PGRYGPGCEQLCGCLNG--------GSCDAATGACRCPTGFLGTDCNLTCPQGRFGPN-- 1257
Query: 180 TTPFHLVSTEFEWLPFGSVAAVQCQAGRGASL-----LCVKQPEGGVGWSRAGPLCLGTG 234
C G+GA+ C+ P RAG C G
Sbjct: 1258 -------------------CTHVCGCGQGAACDPVTGTCLCPP------GRAGVRC-ERG 1291
Query: 235 CSPDNG---GCEHECVEEVDG-----HVSCRCTEGFRLAADGRSCEDPCAQ----APCEQ 282
C P N GCEH C G + SC C G+ GR CE C A C
Sbjct: 1292 C-PQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGW----TGRHCELACPPGRYGAACHL 1346
Query: 283 QCEPGG-----PQGYSCHCRLGF------RPAEDDPH--RCVDTDECQIAGVCQQM---C 326
+C P +C C GF P H C CQ C + C
Sbjct: 1347 ECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRC 1406
Query: 327 VNYVGGFECYCSEGHELEADGISC 350
+ G +C G E + G C
Sbjct: 1407 LCPAGFHGHFCERGCEPGSFGEGC 1430
Score = 35.4 bits (80), Expect = 0.20
Identities = 41/155 (26%), Positives = 49/155 (31%), Gaps = 45/155 (29%)
Query: 222 GWSRAGPLCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQA--- 278
GW G C P C H V G +CRC GF G CE C
Sbjct: 1122 GWF--GEACAQRCSCPPGAACHH-----VTG--ACRCPPGF----TGSGCEQACPPGSFG 1168
Query: 279 -PCEQQCEPGG------PQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCV--NY 329
C Q C+ G P +C C G+ CQQ C Y
Sbjct: 1169 EDCAQMCQCPGENPACHPATGTCSCAAGYHGPS-----------------CQQRCPPGRY 1211
Query: 330 VGGFE--CYCSEGHELEADGISC-SPAGAMGAQAS 361
G E C C G +A +C P G +G +
Sbjct: 1212 GPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCN 1246
Score = 31.2 bits (69), Expect = 3.7
Identities = 48/203 (23%), Positives = 71/203 (34%), Gaps = 50/203 (24%)
Query: 195 FGSVAAVQCQAGRGASLLCVKQPEGGVGWSRAGPLCLGTGCSPD------NGGCEHEC-- 246
+G+ ++C ++ E G R GP G C GC+ C
Sbjct: 1340 YGAACHLECSCHNNSTC------EPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWC 1393
Query: 247 -----VEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCE---------------- 285
+ + G C C GF R CE C Q+C+
Sbjct: 1394 QHGAPCDPISGR--CLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLC 1451
Query: 286 PGGPQGYSCH--CRLG-FRPAEDDPHRCVDTDECQ-IAGVCQQMCVN-YVGGFECYCSEG 340
P G G +C+ CR G F P+ C +C ++G C CV+ Y+G C EG
Sbjct: 1452 PPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCH--CVDGYMGP---TCREG 1506
Query: 341 HEL---EADGISCSPAGAMGAQA 360
L E ++ AG + A +
Sbjct: 1507 GPLRLPENPSLAQGSAGTLPASS 1529
Score = 30.4 bits (67), Expect = 6.4
Identities = 46/189 (24%), Positives = 61/189 (32%), Gaps = 31/189 (16%)
Query: 156 CQFGFEGACPALQDEAGQAGPAVYTTPFHLVSTEFEWLPFGSVAAVQCQAGRGASLLCVK 215
C G C L A P +Y HL + FG + +CQ + + C K
Sbjct: 611 CNCANRGRCHRLYG-ACLCDPGLYGRFCHLTCPPWA---FGPGCSEECQCVQPHTQSCDK 666
Query: 216 QP-----EGGVGWSRAGPLC----LGTGC-----SPDNGGCEHECVEEVDGHVSCRCTEG 261
+ + G R C G GC P C+ V G RC G
Sbjct: 667 RDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACD-----SVSGECGKRCPAG 721
Query: 262 FRLAADGRSCEDPCAQAPCEQQCEPGGPQGY----SCHCRLGFRPAEDDPHRCVDTDECQ 317
F+ G+ C C C GG + C C G R ED D E +
Sbjct: 722 FQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPG-RTGEDCE---ADCPEGR 777
Query: 318 IAGVCQQMC 326
CQ++C
Sbjct: 778 WGLGCQEIC 786
>gi|34734064 fibulin 1 isoform B precursor [Homo sapiens]
Length = 601
Score = 92.4 bits (228), Expect = 1e-18
Identities = 46/115 (40%), Positives = 64/115 (55%), Gaps = 8/115 (6%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 299
C H+C E G C C+ GFRL+ DGRSCED C+ +PC Q+C Y C+CR G
Sbjct: 411 CGHKC-ENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQEC-ANVYGSYQCYCRRG 468
Query: 300 FRPAEDDPHRCVDTDECQI---AGVCQQMCVNYVGGFECYC-SEGHELEADGISC 350
++ ++ D C D DEC + +C C+N G F+C C S G+ L +G +C
Sbjct: 469 YQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNC 523
Score = 62.0 bits (149), Expect = 2e-09
Identities = 37/119 (31%), Positives = 52/119 (43%), Gaps = 14/119 (11%)
Query: 244 HECVEEVDGHVSCR-----CTEGFRLAADGRSCEDPCAQAPCEQQCEPG-----GPQGYS 293
H C+ +G +C+ C G+ L +G C D AP + C G P +
Sbjct: 323 HTCIN-TEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFR 381
Query: 294 CHCRLGFRPAEDDPHRCVDTDECQI--AGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
C C+ G+ + CVD +ECQ +C C N +G + C CS G L DG SC
Sbjct: 382 CECKTGYY-FDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 439
Score = 45.4 bits (106), Expect = 2e-04
Identities = 38/125 (30%), Positives = 53/125 (42%), Gaps = 21/125 (16%)
Query: 240 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGP-----QGYSC 294
G C+ +C + D V C C G++L +DG SCED C G + C
Sbjct: 184 GPCKQQCRDTGD-EVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRC 242
Query: 295 H----CRLGFRPAEDDPHRCVDTDECQIAGV--C--QQMCVNYVGGFEC----YCSEGHE 342
C G+ ED + C D DEC+ +G+ C +C N +G F C C G
Sbjct: 243 QRDSSCGTGYELTED--NSCKDIDECE-SGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 299
Query: 343 LEADG 347
+A G
Sbjct: 300 QDALG 304
Score = 36.2 bits (82), Expect = 0.12
Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 304 EDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
++DP+ D C+ G C+Q C + C C G++L +DG+SC
Sbjct: 171 QEDPYL---NDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSC 214
Score = 35.0 bits (79), Expect = 0.26
Identities = 16/42 (38%), Positives = 25/42 (59%), Gaps = 4/42 (9%)
Query: 235 CSPDNGG--CEHECVEEVDGHVSCRC-TEGFRLAADGRSCED 273
C+ GG C + C+ + G C C + G+RLA +GR+C+D
Sbjct: 485 CALPTGGHICSYRCIN-IPGSFQCSCPSSGYRLAPNGRNCQD 525
>gi|34734068 fibulin 1 isoform A precursor [Homo sapiens]
Length = 566
Score = 92.4 bits (228), Expect = 1e-18
Identities = 46/115 (40%), Positives = 64/115 (55%), Gaps = 8/115 (6%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 299
C H+C E G C C+ GFRL+ DGRSCED C+ +PC Q+C Y C+CR G
Sbjct: 411 CGHKC-ENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQEC-ANVYGSYQCYCRRG 468
Query: 300 FRPAEDDPHRCVDTDECQI---AGVCQQMCVNYVGGFECYC-SEGHELEADGISC 350
++ ++ D C D DEC + +C C+N G F+C C S G+ L +G +C
Sbjct: 469 YQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNC 523
Score = 62.0 bits (149), Expect = 2e-09
Identities = 37/119 (31%), Positives = 52/119 (43%), Gaps = 14/119 (11%)
Query: 244 HECVEEVDGHVSCR-----CTEGFRLAADGRSCEDPCAQAPCEQQCEPG-----GPQGYS 293
H C+ +G +C+ C G+ L +G C D AP + C G P +
Sbjct: 323 HTCIN-TEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFR 381
Query: 294 CHCRLGFRPAEDDPHRCVDTDECQI--AGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
C C+ G+ + CVD +ECQ +C C N +G + C CS G L DG SC
Sbjct: 382 CECKTGYY-FDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 439
Score = 45.4 bits (106), Expect = 2e-04
Identities = 38/125 (30%), Positives = 53/125 (42%), Gaps = 21/125 (16%)
Query: 240 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGP-----QGYSC 294
G C+ +C + D V C C G++L +DG SCED C G + C
Sbjct: 184 GPCKQQCRDTGD-EVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRC 242
Query: 295 H----CRLGFRPAEDDPHRCVDTDECQIAGV--C--QQMCVNYVGGFEC----YCSEGHE 342
C G+ ED + C D DEC+ +G+ C +C N +G F C C G
Sbjct: 243 QRDSSCGTGYELTED--NSCKDIDECE-SGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 299
Query: 343 LEADG 347
+A G
Sbjct: 300 QDALG 304
Score = 36.2 bits (82), Expect = 0.12
Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 304 EDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
++DP+ D C+ G C+Q C + C C G++L +DG+SC
Sbjct: 171 QEDPYL---NDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSC 214
Score = 35.0 bits (79), Expect = 0.26
Identities = 16/42 (38%), Positives = 25/42 (59%), Gaps = 4/42 (9%)
Query: 235 CSPDNGG--CEHECVEEVDGHVSCRC-TEGFRLAADGRSCED 273
C+ GG C + C+ + G C C + G+RLA +GR+C+D
Sbjct: 485 CALPTGGHICSYRCIN-IPGSFQCSCPSSGYRLAPNGRNCQD 525
>gi|34734066 fibulin 1 isoform D [Homo sapiens]
Length = 703
Score = 92.4 bits (228), Expect = 1e-18
Identities = 46/115 (40%), Positives = 64/115 (55%), Gaps = 8/115 (6%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 299
C H+C E G C C+ GFRL+ DGRSCED C+ +PC Q+C Y C+CR G
Sbjct: 411 CGHKC-ENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQEC-ANVYGSYQCYCRRG 468
Query: 300 FRPAEDDPHRCVDTDECQI---AGVCQQMCVNYVGGFECYC-SEGHELEADGISC 350
++ ++ D C D DEC + +C C+N G F+C C S G+ L +G +C
Sbjct: 469 YQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNC 523
Score = 62.0 bits (149), Expect = 2e-09
Identities = 37/119 (31%), Positives = 52/119 (43%), Gaps = 14/119 (11%)
Query: 244 HECVEEVDGHVSCR-----CTEGFRLAADGRSCEDPCAQAPCEQQCEPG-----GPQGYS 293
H C+ +G +C+ C G+ L +G C D AP + C G P +
Sbjct: 323 HTCIN-TEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFR 381
Query: 294 CHCRLGFRPAEDDPHRCVDTDECQI--AGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
C C+ G+ + CVD +ECQ +C C N +G + C CS G L DG SC
Sbjct: 382 CECKTGYY-FDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 439
Score = 45.4 bits (106), Expect = 2e-04
Identities = 38/125 (30%), Positives = 53/125 (42%), Gaps = 21/125 (16%)
Query: 240 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGP-----QGYSC 294
G C+ +C + D V C C G++L +DG SCED C G + C
Sbjct: 184 GPCKQQCRDTGD-EVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRC 242
Query: 295 H----CRLGFRPAEDDPHRCVDTDECQIAGV--C--QQMCVNYVGGFEC----YCSEGHE 342
C G+ ED + C D DEC+ +G+ C +C N +G F C C G
Sbjct: 243 QRDSSCGTGYELTED--NSCKDIDECE-SGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 299
Query: 343 LEADG 347
+A G
Sbjct: 300 QDALG 304
Score = 36.2 bits (82), Expect = 0.12
Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 304 EDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
++DP+ D C+ G C+Q C + C C G++L +DG+SC
Sbjct: 171 QEDPYL---NDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSC 214
Score = 35.0 bits (79), Expect = 0.26
Identities = 16/42 (38%), Positives = 25/42 (59%), Gaps = 4/42 (9%)
Query: 235 CSPDNGG--CEHECVEEVDGHVSCRC-TEGFRLAADGRSCED 273
C+ GG C + C+ + G C C + G+RLA +GR+C+D
Sbjct: 485 CALPTGGHICSYRCIN-IPGSFQCSCPSSGYRLAPNGRNCQD 525
>gi|34734062 fibulin 1 isoform C precursor [Homo sapiens]
Length = 683
Score = 92.4 bits (228), Expect = 1e-18
Identities = 46/115 (40%), Positives = 64/115 (55%), Gaps = 8/115 (6%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 299
C H+C E G C C+ GFRL+ DGRSCED C+ +PC Q+C Y C+CR G
Sbjct: 411 CGHKC-ENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQEC-ANVYGSYQCYCRRG 468
Query: 300 FRPAEDDPHRCVDTDECQI---AGVCQQMCVNYVGGFECYC-SEGHELEADGISC 350
++ ++ D C D DEC + +C C+N G F+C C S G+ L +G +C
Sbjct: 469 YQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNC 523
Score = 62.0 bits (149), Expect = 2e-09
Identities = 37/119 (31%), Positives = 52/119 (43%), Gaps = 14/119 (11%)
Query: 244 HECVEEVDGHVSCR-----CTEGFRLAADGRSCEDPCAQAPCEQQCEPG-----GPQGYS 293
H C+ +G +C+ C G+ L +G C D AP + C G P +
Sbjct: 323 HTCIN-TEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFR 381
Query: 294 CHCRLGFRPAEDDPHRCVDTDECQI--AGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
C C+ G+ + CVD +ECQ +C C N +G + C CS G L DG SC
Sbjct: 382 CECKTGYY-FDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 439
Score = 45.4 bits (106), Expect = 2e-04
Identities = 38/125 (30%), Positives = 53/125 (42%), Gaps = 21/125 (16%)
Query: 240 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGP-----QGYSC 294
G C+ +C + D V C C G++L +DG SCED C G + C
Sbjct: 184 GPCKQQCRDTGD-EVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRC 242
Query: 295 H----CRLGFRPAEDDPHRCVDTDECQIAGV--C--QQMCVNYVGGFEC----YCSEGHE 342
C G+ ED + C D DEC+ +G+ C +C N +G F C C G
Sbjct: 243 QRDSSCGTGYELTED--NSCKDIDECE-SGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 299
Query: 343 LEADG 347
+A G
Sbjct: 300 QDALG 304
Score = 36.2 bits (82), Expect = 0.12
Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 304 EDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
++DP+ D C+ G C+Q C + C C G++L +DG+SC
Sbjct: 171 QEDPYL---NDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSC 214
Score = 35.0 bits (79), Expect = 0.26
Identities = 16/42 (38%), Positives = 25/42 (59%), Gaps = 4/42 (9%)
Query: 235 CSPDNGG--CEHECVEEVDGHVSCRC-TEGFRLAADGRSCED 273
C+ GG C + C+ + G C C + G+RLA +GR+C+D
Sbjct: 485 CALPTGGHICSYRCIN-IPGSFQCSCPSSGYRLAPNGRNCQD 525
>gi|51873055 fibulin 2 isoform b precursor [Homo sapiens]
Length = 1184
Score = 89.0 bits (219), Expect = 2e-17
Identities = 50/114 (43%), Positives = 63/114 (55%), Gaps = 8/114 (7%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 299
C+H C E G C C GF LAADG+ CED C C Q+C Y C+CR G
Sbjct: 913 CQHTC-ENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECA-NIYGSYQCYCRQG 970
Query: 300 FRPAEDDPHRCVDTDEC-QIAGV-CQQMCVNYVGGFECYCSE-GHELEADGISC 350
++ AED H C D DEC Q AG+ C C+N G ++C C E G+ + A+G SC
Sbjct: 971 YQLAEDG-HTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSC 1023
Score = 76.3 bits (186), Expect = 1e-13
Identities = 50/133 (37%), Positives = 63/133 (47%), Gaps = 17/133 (12%)
Query: 232 GTGCSPDNGGCE---HECVE-----EVDGHVSCRCTEGFRLAADGRSCED--PCAQAP-- 279
GT C D CE H C E + G C C GF+ A GR C D C +P
Sbjct: 853 GTKCV-DVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGR 911
Query: 280 -CEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCS 338
C+ CE Y C C GF A D RC D +EC+ A C Q C N G ++CYC
Sbjct: 912 LCQHTCE-NTLGSYRCSCASGFLLAADGK-RCEDVNECE-AQRCSQECANIYGSYQCYCR 968
Query: 339 EGHELEADGISCS 351
+G++L DG +C+
Sbjct: 969 QGYQLAEDGHTCT 981
Score = 60.5 bits (145), Expect = 6e-09
Identities = 45/160 (28%), Positives = 63/160 (39%), Gaps = 26/160 (16%)
Query: 246 CVEEVDGHVSCR----CTEGFRLAADGRSCEDPCAQAPCEQQCEPGG-----PQGYSCHC 296
C+ V + R C G+ + DG C D +C G P Y C C
Sbjct: 827 CINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDC 886
Query: 297 RLGFRPAEDDPHRCVDTDECQIAG--VCQQMCVNYVGGFECYCSEGHELEADGISCSPAG 354
+ GF+ + C+D +EC + +CQ C N +G + C C+ G L ADG C
Sbjct: 887 KAGFQ-RDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVN 945
Query: 355 AMGAQ-ASQDL-------------GDELLDDGEDEEDEDE 380
AQ SQ+ G +L +DG D DE
Sbjct: 946 ECEAQRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDE 985
Score = 57.4 bits (137), Expect = 5e-08
Identities = 34/109 (31%), Positives = 47/109 (43%), Gaps = 7/109 (6%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGYSCHCRLGFR 301
C+H C+ V G C C GF L DGR+C P P +P PQ +
Sbjct: 616 CQHLCINTV-GSYHCACFPGFSLQDDGRTCR-PEGHPP-----QPEAPQEPALKSEFSQV 668
Query: 302 PAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
+ P + C+ G C+Q+C G C C G+ + ADG+SC
Sbjct: 669 ASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSC 717
Score = 48.5 bits (114), Expect = 2e-05
Identities = 32/106 (30%), Positives = 45/106 (42%), Gaps = 8/106 (7%)
Query: 253 HVSCRCTEGFR--LAADGRSCEDPCAQAPCEQQCEPGGPQGYSCHCRLGFRPAEDDPHRC 310
HV C EG + + R +P A + E G + S LG +
Sbjct: 547 HVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALS----LGTEAELPNSLPG 602
Query: 311 VDTDECQI--AGVCQQMCVNYVGGFECYCSEGHELEADGISCSPAG 354
D DEC + +CQ +C+N VG + C C G L+ DG +C P G
Sbjct: 603 DDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEG 648
Score = 46.2 bits (108), Expect = 1e-04
Identities = 37/126 (29%), Positives = 50/126 (39%), Gaps = 20/126 (15%)
Query: 238 DNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGP-----QGY 292
DNG C+ C V G C C G+ + ADG SCED C G +
Sbjct: 685 DNGPCKQVC-STVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSF 743
Query: 293 SCH----CRLGFRPAEDDPHRCVDTDECQI-AGVCQQ--MCVNYVGGFECY----CSEGH 341
C+ C G+ + + C D DEC + CQ +C N G F C C +G
Sbjct: 744 HCYKALTCEPGYALKDGE---CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF 800
Query: 342 ELEADG 347
+ +G
Sbjct: 801 LQDPEG 806
Score = 30.4 bits (67), Expect = 6.4
Identities = 14/33 (42%), Positives = 19/33 (57%), Gaps = 2/33 (6%)
Query: 242 CEHECVEEVDGHVSCRCTE-GFRLAADGRSCED 273
C C+ V G C C E G+ + A+GRSC+D
Sbjct: 994 CTFRCLN-VPGSYQCACPEQGYTMTANGRSCKD 1025
>gi|51873053 fibulin 2 isoform a precursor [Homo sapiens]
Length = 1231
Score = 89.0 bits (219), Expect = 2e-17
Identities = 50/114 (43%), Positives = 63/114 (55%), Gaps = 8/114 (7%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 299
C+H C E G C C GF LAADG+ CED C C Q+C Y C+CR G
Sbjct: 960 CQHTC-ENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECA-NIYGSYQCYCRQG 1017
Query: 300 FRPAEDDPHRCVDTDEC-QIAGV-CQQMCVNYVGGFECYCSE-GHELEADGISC 350
++ AED H C D DEC Q AG+ C C+N G ++C C E G+ + A+G SC
Sbjct: 1018 YQLAEDG-HTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSC 1070
Score = 76.3 bits (186), Expect = 1e-13
Identities = 50/133 (37%), Positives = 63/133 (47%), Gaps = 17/133 (12%)
Query: 232 GTGCSPDNGGCE---HECVE-----EVDGHVSCRCTEGFRLAADGRSCED--PCAQAP-- 279
GT C D CE H C E + G C C GF+ A GR C D C +P
Sbjct: 900 GTKCV-DVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGR 958
Query: 280 -CEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCS 338
C+ CE Y C C GF A D RC D +EC+ A C Q C N G ++CYC
Sbjct: 959 LCQHTCE-NTLGSYRCSCASGFLLAADGK-RCEDVNECE-AQRCSQECANIYGSYQCYCR 1015
Query: 339 EGHELEADGISCS 351
+G++L DG +C+
Sbjct: 1016 QGYQLAEDGHTCT 1028
Score = 60.5 bits (145), Expect = 6e-09
Identities = 45/160 (28%), Positives = 63/160 (39%), Gaps = 26/160 (16%)
Query: 246 CVEEVDGHVSCR----CTEGFRLAADGRSCEDPCAQAPCEQQCEPGG-----PQGYSCHC 296
C+ V + R C G+ + DG C D +C G P Y C C
Sbjct: 874 CINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDC 933
Query: 297 RLGFRPAEDDPHRCVDTDECQIAG--VCQQMCVNYVGGFECYCSEGHELEADGISCSPAG 354
+ GF+ + C+D +EC + +CQ C N +G + C C+ G L ADG C
Sbjct: 934 KAGFQ-RDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVN 992
Query: 355 AMGAQ-ASQDL-------------GDELLDDGEDEEDEDE 380
AQ SQ+ G +L +DG D DE
Sbjct: 993 ECEAQRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDE 1032
Score = 57.4 bits (137), Expect = 5e-08
Identities = 34/109 (31%), Positives = 47/109 (43%), Gaps = 7/109 (6%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGYSCHCRLGFR 301
C+H C+ V G C C GF L DGR+C P P +P PQ +
Sbjct: 616 CQHLCINTV-GSYHCACFPGFSLQDDGRTCR-PEGHPP-----QPEAPQEPALKSEFSQV 668
Query: 302 PAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
+ P + C+ G C+Q+C G C C G+ + ADG+SC
Sbjct: 669 ASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSC 717
Score = 48.5 bits (114), Expect = 2e-05
Identities = 32/106 (30%), Positives = 45/106 (42%), Gaps = 8/106 (7%)
Query: 253 HVSCRCTEGFR--LAADGRSCEDPCAQAPCEQQCEPGGPQGYSCHCRLGFRPAEDDPHRC 310
HV C EG + + R +P A + E G + S LG +
Sbjct: 547 HVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALS----LGTEAELPNSLPG 602
Query: 311 VDTDECQI--AGVCQQMCVNYVGGFECYCSEGHELEADGISCSPAG 354
D DEC + +CQ +C+N VG + C C G L+ DG +C P G
Sbjct: 603 DDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEG 648
Score = 47.8 bits (112), Expect = 4e-05
Identities = 41/142 (28%), Positives = 56/142 (39%), Gaps = 20/142 (14%)
Query: 238 DNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDP---------CAQAP-CEQQCEPG 287
DNG C+ C V G C C G+ + ADG SCED C++ C
Sbjct: 685 DNGPCKQVC-STVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSF 743
Query: 288 GPQGYSCHCRLGFRPAEDDPHRCVDTDECQI-AGVCQ--QMCVNYVGGFECY----CSEG 340
++ C G+ + +CVD +EC C + CVN +G F CY C G
Sbjct: 744 YCVNHTVLCADGY--ILNAHRKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPG 801
Query: 341 HELEADGISCSPAGAMGAQASQ 362
+ L+ AMG Q
Sbjct: 802 YALKDGECEDVDECAMGTHTCQ 823
Score = 30.4 bits (67), Expect = 6.4
Identities = 14/33 (42%), Positives = 19/33 (57%), Gaps = 2/33 (6%)
Query: 242 CEHECVEEVDGHVSCRCTE-GFRLAADGRSCED 273
C C+ V G C C E G+ + A+GRSC+D
Sbjct: 1041 CTFRCLN-VPGSYQCACPEQGYTMTANGRSCKD 1072
>gi|114431244 von Willebrand factor C and EGF domains [Homo sapiens]
Length = 955
Score = 86.3 bits (212), Expect = 1e-16
Identities = 47/114 (41%), Positives = 57/114 (50%), Gaps = 8/114 (7%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCEDP--CAQAPCEQQCEPGGPQGYSCHCRLG 299
CE CV G V C C G +L+AD SC+D C PC+Q+C+ Y C CR G
Sbjct: 151 CEGHCVNTEGGFV-CECGPGMQLSADRHSCQDTDECLGTPCQQRCK-NSIGSYKCSCRTG 208
Query: 300 FRPAEDDPHRCVDTDECQIA---GVCQQMCVNYVGGFECYCSEGHELEADGISC 350
F + H CVD +EC+ VC C N VG F C C G L AD +SC
Sbjct: 209 FH-LHGNRHSCVDVNECRRPLERRVCHHSCHNTVGSFLCTCRPGFRLRADRVSC 261
Score = 66.6 bits (161), Expect = 8e-11
Identities = 52/152 (34%), Positives = 65/152 (42%), Gaps = 37/152 (24%)
Query: 225 RAGP-LCL---GTGC----SPDNGGCEHECVEEVDGHV-----SCRCTEGFRLAADGRSC 271
R GP +CL G+GC +P GG GH S C G +A + SC
Sbjct: 39 RLGPHVCLSGFGSGCCPGWAPSMGG----------GHCTLPLCSFGCGSGICIAPNVCSC 88
Query: 272 ED------------PCAQAPCEQQCEPGGPQGYSCHCRLGFRPAEDDPH-RCVDTDECQI 318
+D PC + C+ C GG Q + C +GF E RC D DEC +
Sbjct: 89 QDGEQGATCPETHGPCGEYGCDLTCNHGGCQEVARVCPVGFSMTETAVGIRCTDIDEC-V 147
Query: 319 AGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
C+ CVN GGF C C G +L AD SC
Sbjct: 148 TSSCEGHCVNTEGGFVCECGPGMQLSADRHSC 179
Score = 33.1 bits (74), Expect = 0.98
Identities = 16/31 (51%), Positives = 16/31 (51%), Gaps = 1/31 (3%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCE 272
C H C V G C C GFRL AD SCE
Sbjct: 233 CHHSCHNTV-GSFLCTCRPGFRLRADRVSCE 262
>gi|10190748 CEGP1 protein [Homo sapiens]
Length = 999
Score = 82.4 bits (202), Expect = 1e-15
Identities = 45/120 (37%), Positives = 63/120 (52%), Gaps = 8/120 (6%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCA-QAPCEQQCEPGGPQG 291
C NGGC+H C + + G C C +GF+L D +SC+D C+ C+ C P
Sbjct: 327 CQTRNGGCDHFC-KNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDHSCI-NHPGT 384
Query: 292 YSCHCRLGFRPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGGFECYCSEGHELEADGISC 350
++C C G+ C DT+EC I G CQQ+CVN VG +EC C G++L + C
Sbjct: 385 FACACNRGYTLYGFT--HCGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNKKDC 442
Score = 78.2 bits (191), Expect = 3e-14
Identities = 38/113 (33%), Positives = 56/113 (49%), Gaps = 7/113 (6%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED----PCAQAPCEQQCEPGGPQ 290
C+ +NGGC+ C + G V C C GF L DG++C+D C+ C+
Sbjct: 286 CAVNNGGCDRTCKDTSTG-VHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCK-NIVG 343
Query: 291 GYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHEL 343
+ C C+ GF+ D+ C D DEC + C C+N+ G F C C+ G+ L
Sbjct: 344 SFDCGCKKGFKLLTDEKS-CQDVDECSLDRTCDHSCINHPGTFACACNRGYTL 395
Score = 64.3 bits (155), Expect = 4e-10
Identities = 39/101 (38%), Positives = 48/101 (47%), Gaps = 10/101 (9%)
Query: 256 CRCTEGFRLAADGRSCED--PCAQ---APCEQQCEPGGPQGYSCHCRLGFRPAEDDPHRC 310
C C G++ +GR CED C C C P Y C C GF A D H C
Sbjct: 71 CSCKPGYQ--GEGRQCEDIDECGNELNGGCVHDCL-NIPGNYRCTCFDGFMLAHDG-HNC 126
Query: 311 VDTDEC-QIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
+D DEC + G CQ CVN +G +EC C EG L + +C
Sbjct: 127 LDVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTC 167
Score = 63.2 bits (152), Expect = 9e-10
Identities = 40/125 (32%), Positives = 55/125 (44%), Gaps = 13/125 (10%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQA--------PCEQQCEP 286
C +NGGC+H CV V G C C EGF L+ + +C + C C+
Sbjct: 132 CLENNGGCQHTCVN-VMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKE 190
Query: 287 GGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGGFECYCSEGHELEA 345
+C CR GF A++ C+ T C G CQ C + G EC C +++
Sbjct: 191 APRGSVACECRPGFELAKNQ-RDCILT--CNHGNGGCQHSCDDTADGPECSCHPQYKMHT 247
Query: 346 DGISC 350
DG SC
Sbjct: 248 DGRSC 252
Score = 58.9 bits (141), Expect = 2e-08
Identities = 43/145 (29%), Positives = 60/145 (41%), Gaps = 13/145 (8%)
Query: 239 NGGCEHECVEEVDGHVSCRCTEGFRLAADGRSC--EDPCAQ--APCEQQCEPGGPQGYSC 294
NGGC H+C+ + G+ C C +GF LA DG +C D C + C+ C Y C
Sbjct: 95 NGGCVHDCLN-IPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTC-VNVMGSYEC 152
Query: 295 HCRLGFRPAEDDPHRCVDTDECQIAGV-----CQQMCVNYV-GGFECYCSEGHELEADGI 348
C+ GF D+ H C+ E ++ + C +C G C C G EL +
Sbjct: 153 CCKEGFF-LSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQR 211
Query: 349 SCSPAGAMGAQASQDLGDELLDDGE 373
C G Q D+ D E
Sbjct: 212 DCILTCNHGNGGCQHSCDDTADGPE 236
Score = 54.3 bits (129), Expect = 4e-07
Identities = 37/150 (24%), Positives = 53/150 (35%), Gaps = 33/150 (22%)
Query: 232 GTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPC--AQAPCEQQCEPGGP 289
G C + GC H C E G V+C C GF LA + R C C C+ C+
Sbjct: 174 GLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDCILTCNHGNGGCQHSCDDTA- 232
Query: 290 QGYSCHCRLGFRPAEDDPHRCVDTDE----------------------------CQI-AG 320
G C C ++ D C++ ++ C + G
Sbjct: 233 DGPECSCHPQYK-MHTDGRSCLEREDTVLEVTESNTTSVVDGDKRVKRRLLMETCAVNNG 291
Query: 321 VCQQMCVNYVGGFECYCSEGHELEADGISC 350
C + C + G C C G L+ DG +C
Sbjct: 292 GCDRTCKDTSTGVHCSCPVGFTLQLDGKTC 321
>gi|62548862 matrilin 2 isoform b precursor [Homo sapiens]
Length = 937
Score = 81.6 bits (200), Expect = 2e-15
Identities = 53/139 (38%), Positives = 65/139 (46%), Gaps = 8/139 (5%)
Query: 217 PEGGVGWSRAGPLCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSC--EDP 274
PEG V S C+ + GCEH CV D V C+C EG+ L DG++C +D
Sbjct: 511 PEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFV-CQCFEGYILREDGKTCRRKDV 569
Query: 275 CAQAP--CEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGV-CQQMCVNYVG 331
C CE C Y+C C GFR AED RC D C+ C+ +CVN
Sbjct: 570 CQAIDHGCEHICV-NSDDSYTCECLEGFRLAEDGK-RCRRKDVCKSTHHGCEHICVNNGN 627
Query: 332 GFECYCSEGHELEADGISC 350
+ C CSEG L DG C
Sbjct: 628 SYICKCSEGFVLAEDGRRC 646
Score = 79.0 bits (193), Expect = 2e-14
Identities = 45/122 (36%), Positives = 61/122 (50%), Gaps = 8/122 (6%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCAQAP--CEQQCEPGGPQ 290
C+ + GCEHECV + + CRC G+ L +G++C D CAQ CEQ C
Sbjct: 406 CALNKPGCEHECVNMEESYY-CRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCL-NTED 463
Query: 291 GYSCHCRLGFRPAEDDPHRCVDTDECQIAGV-CQQMCVNYVGGFECYCSEGHELEADGIS 349
+ C C GF +D C D C ++ C+ CVN F C C EGH L +DG +
Sbjct: 464 SFVCQCSEGFL-INEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKT 522
Query: 350 CS 351
C+
Sbjct: 523 CA 524
Score = 73.9 bits (180), Expect = 5e-13
Identities = 46/128 (35%), Positives = 59/128 (46%), Gaps = 8/128 (6%)
Query: 229 LCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSC--EDPCAQAP--CEQQC 284
LC CS C H C+ + G CRC +G+ L +D +C +D CA CEQ C
Sbjct: 236 LCTAHMCSTLEHNCAHFCIN-IPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLC 294
Query: 285 EPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGV-CQQMCVNYVGGFECYCSEGHEL 343
P + C C G+ AED RCV D C C+ CVN G + C C EG L
Sbjct: 295 V-NVPGSFVCQCYSGYALAEDGK-RCVAVDYCASENHGCEHECVNADGSYLCQCHEGFAL 352
Query: 344 EADGISCS 351
D +C+
Sbjct: 353 NPDKKTCT 360
Score = 68.6 bits (166), Expect = 2e-11
Identities = 43/121 (35%), Positives = 56/121 (46%), Gaps = 8/121 (6%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCAQAP--CEQQCEPGGPQ 290
C + GCE+ CV +D +C+C EG L +DG++C D CA CE C
Sbjct: 488 CLLSDHGCEYSCVN-MDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSC-VSSED 545
Query: 291 GYSCHCRLGFRPAEDDPHRCVDTDECQ-IAGVCQQMCVNYVGGFECYCSEGHELEADGIS 349
+ C C G+ ED C D CQ I C+ +CVN + C C EG L DG
Sbjct: 546 SFVCQCFEGYILREDG-KTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKR 604
Query: 350 C 350
C
Sbjct: 605 C 605
Score = 66.6 bits (161), Expect = 8e-11
Identities = 41/121 (33%), Positives = 53/121 (43%), Gaps = 8/121 (6%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCAQAP--CEQQCEPGGPQ 290
C+ ++ CE CV V G C+C G+ LA DG+ C D CA CE +C
Sbjct: 283 CAMEDHNCEQLCVN-VPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECV-NADG 340
Query: 291 GYSCHCRLGFRPAEDDPHRCVDTDECQIAGV-CQQMCVNYVGGFECYCSEGHELEADGIS 349
Y C C GF D C D C + CQ CVN + C+C +G L D +
Sbjct: 341 SYLCQCHEGFA-LNPDKKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKT 399
Query: 350 C 350
C
Sbjct: 400 C 400
Score = 46.6 bits (109), Expect = 9e-05
Identities = 20/47 (42%), Positives = 29/47 (61%), Gaps = 2/47 (4%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCE 281
C + GCEH CV + ++ C+C+EGF LA DGR C+ C + P +
Sbjct: 611 CKSTHHGCEHICVNNGNSYI-CKCSEGFVLAEDGRRCK-KCTEGPID 655
>gi|62548860 matrilin 2 isoform a precursor [Homo sapiens]
Length = 956
Score = 81.6 bits (200), Expect = 2e-15
Identities = 53/139 (38%), Positives = 65/139 (46%), Gaps = 8/139 (5%)
Query: 217 PEGGVGWSRAGPLCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSC--EDP 274
PEG V S C+ + GCEH CV D V C+C EG+ L DG++C +D
Sbjct: 511 PEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFV-CQCFEGYILREDGKTCRRKDV 569
Query: 275 CAQAP--CEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGV-CQQMCVNYVG 331
C CE C Y+C C GFR AED RC D C+ C+ +CVN
Sbjct: 570 CQAIDHGCEHICV-NSDDSYTCECLEGFRLAEDGK-RCRRKDVCKSTHHGCEHICVNNGN 627
Query: 332 GFECYCSEGHELEADGISC 350
+ C CSEG L DG C
Sbjct: 628 SYICKCSEGFVLAEDGRRC 646
Score = 79.0 bits (193), Expect = 2e-14
Identities = 45/122 (36%), Positives = 61/122 (50%), Gaps = 8/122 (6%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCAQAP--CEQQCEPGGPQ 290
C+ + GCEHECV + + CRC G+ L +G++C D CAQ CEQ C
Sbjct: 406 CALNKPGCEHECVNMEESYY-CRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCL-NTED 463
Query: 291 GYSCHCRLGFRPAEDDPHRCVDTDECQIAGV-CQQMCVNYVGGFECYCSEGHELEADGIS 349
+ C C GF +D C D C ++ C+ CVN F C C EGH L +DG +
Sbjct: 464 SFVCQCSEGFL-INEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKT 522
Query: 350 CS 351
C+
Sbjct: 523 CA 524
Score = 73.9 bits (180), Expect = 5e-13
Identities = 46/128 (35%), Positives = 59/128 (46%), Gaps = 8/128 (6%)
Query: 229 LCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSC--EDPCAQAP--CEQQC 284
LC CS C H C+ + G CRC +G+ L +D +C +D CA CEQ C
Sbjct: 236 LCTAHMCSTLEHNCAHFCIN-IPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLC 294
Query: 285 EPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGV-CQQMCVNYVGGFECYCSEGHEL 343
P + C C G+ AED RCV D C C+ CVN G + C C EG L
Sbjct: 295 V-NVPGSFVCQCYSGYALAEDGK-RCVAVDYCASENHGCEHECVNADGSYLCQCHEGFAL 352
Query: 344 EADGISCS 351
D +C+
Sbjct: 353 NPDKKTCT 360
Score = 68.6 bits (166), Expect = 2e-11
Identities = 43/121 (35%), Positives = 56/121 (46%), Gaps = 8/121 (6%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCAQAP--CEQQCEPGGPQ 290
C + GCE+ CV +D +C+C EG L +DG++C D CA CE C
Sbjct: 488 CLLSDHGCEYSCVN-MDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSC-VSSED 545
Query: 291 GYSCHCRLGFRPAEDDPHRCVDTDECQ-IAGVCQQMCVNYVGGFECYCSEGHELEADGIS 349
+ C C G+ ED C D CQ I C+ +CVN + C C EG L DG
Sbjct: 546 SFVCQCFEGYILREDG-KTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKR 604
Query: 350 C 350
C
Sbjct: 605 C 605
Score = 66.6 bits (161), Expect = 8e-11
Identities = 41/121 (33%), Positives = 53/121 (43%), Gaps = 8/121 (6%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCAQAP--CEQQCEPGGPQ 290
C+ ++ CE CV V G C+C G+ LA DG+ C D CA CE +C
Sbjct: 283 CAMEDHNCEQLCVN-VPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECV-NADG 340
Query: 291 GYSCHCRLGFRPAEDDPHRCVDTDECQIAGV-CQQMCVNYVGGFECYCSEGHELEADGIS 349
Y C C GF D C D C + CQ CVN + C+C +G L D +
Sbjct: 341 SYLCQCHEGFA-LNPDKKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKT 399
Query: 350 C 350
C
Sbjct: 400 C 400
Score = 46.6 bits (109), Expect = 9e-05
Identities = 20/47 (42%), Positives = 29/47 (61%), Gaps = 2/47 (4%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCE 281
C + GCEH CV + ++ C+C+EGF LA DGR C+ C + P +
Sbjct: 611 CKSTHHGCEHICVNNGNSYI-CKCSEGFVLAEDGRRCK-KCTEGPID 655
>gi|31377568 signal peptide, CUB domain, EGF-like 3 [Homo sapiens]
Length = 993
Score = 81.6 bits (200), Expect = 2e-15
Identities = 49/153 (32%), Positives = 72/153 (47%), Gaps = 13/153 (8%)
Query: 208 GASLLCVKQPEGGVGWSRAGPLCLGTG-------CSPDNGGCEHECVEEVDGHVSCRCTE 260
G + +C + P+GG+ L C+ NGGC+H C + G C C
Sbjct: 167 GCAHICRETPKGGIACECRPGFELTKNQRDCKLTCNYGNGGCQHTCDDTEQGP-RCGCHI 225
Query: 261 GFRLAADGRSCEDPCA--QAPCEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQI 318
F L DG++C + CA C+ +C G C C +GF + D C D DEC++
Sbjct: 226 KFVLHTDGKTCIETCAVNNGGCDSKCHDAAT-GVHCTCPVGFM-LQPDRKTCKDIDECRL 283
Query: 319 A-GVCQQMCVNYVGGFECYCSEGHELEADGISC 350
G C +C N VG FEC C +G++L + +C
Sbjct: 284 NNGGCDHICRNTVGSFECSCKKGYKLLINERNC 316
Score = 74.7 bits (182), Expect = 3e-13
Identities = 40/121 (33%), Positives = 59/121 (48%), Gaps = 8/121 (6%)
Query: 227 GPLCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCA--QAPCEQ 282
G C+ T C+ +NGGC+ +C + G V C C GF L D ++C+D C C+
Sbjct: 233 GKTCIET-CAVNNGGCDSKCHDAATG-VHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDH 290
Query: 283 QCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHE 342
C + C C+ G++ ++ C D DEC C +CVN G F+C C G+
Sbjct: 291 ICR-NTVGSFECSCKKGYKLLINE-RNCQDIDECSFDRTCDHICVNTPGSFQCLCHRGYL 348
Query: 343 L 343
L
Sbjct: 349 L 349
Score = 70.1 bits (170), Expect = 7e-12
Identities = 45/126 (35%), Positives = 58/126 (46%), Gaps = 19/126 (15%)
Query: 238 DNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSC--EDPCAQ--APCEQQCEPGGPQGYS 293
DN GC H+CV + G+ C C +GF LA DG +C D CA+ C+Q C Y
Sbjct: 78 DNAGCVHDCV-NIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSC-VNMMGSYE 135
Query: 294 CHCRLGFRPAEDDPHRCVDTDE----CQ-----IAGVCQQMCVNYVGGFECYCSEGHELE 344
CHCR GF D+ H C+ E C A +C++ GG C C G EL
Sbjct: 136 CHCREGFF-LSDNQHTCIQRPEEGMNCMNKNHGCAHICRE---TPKGGIACECRPGFELT 191
Query: 345 ADGISC 350
+ C
Sbjct: 192 KNQRDC 197
Score = 68.9 bits (167), Expect = 2e-11
Identities = 46/124 (37%), Positives = 57/124 (45%), Gaps = 22/124 (17%)
Query: 245 ECVEEVDG-HVS-----------CRCTEGFRLAADGRSCED--PCAQ---APCEQQCEPG 287
ECVE D H+ C C G+ DG+ C+D C + A C C
Sbjct: 32 ECVEGTDNCHIDAICQNTPRSYKCICKSGY--TGDGKHCKDVDECEREDNAGCVHDCV-N 88
Query: 288 GPQGYSCHCRLGFRPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGGFECYCSEGHELEAD 346
P Y C C GF A D H C+D DEC G CQQ CVN +G +EC+C EG L +
Sbjct: 89 IPGNYRCTCYDGFHLAHDG-HNCLDVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSDN 147
Query: 347 GISC 350
+C
Sbjct: 148 QHTC 151
Score = 65.5 bits (158), Expect = 2e-10
Identities = 40/122 (32%), Positives = 58/122 (47%), Gaps = 9/122 (7%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCA-QAPCEQQCEPGGPQG 291
C +NGGC+H C V G C C +G++L + R+C+D C+ C+ C P
Sbjct: 281 CRLNNGGCDHICRNTV-GSFECSCKKGYKLLINERNCQDIDECSFDRTCDHICV-NTPGS 338
Query: 292 YSCHCRLGFRPAEDDPHRCVDTDECQI-AGVCQQMCVNYVGGFECYCSEGH-ELEADGIS 349
+ C C G+ C D DEC I G C+ C+N G ++C C G L +G
Sbjct: 339 FQCLCHRGYLLYGIT--HCGDVDECSINRGGCRFGCINTPGSYQCTCPAGQGRLHWNGKD 396
Query: 350 CS 351
C+
Sbjct: 397 CT 398
Score = 53.1 bits (126), Expect = 9e-07
Identities = 37/133 (27%), Positives = 51/133 (38%), Gaps = 29/133 (21%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAP------------CEQ 282
C+ NGGC+ CV + G C C EGF L+ + + C Q P C
Sbjct: 116 CAEGNGGCQQSCVNMM-GSYECHCREGFFLSDN----QHTCIQRPEEGMNCMNKNHGCAH 170
Query: 283 QCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIA-----GVCQQMCVNYVGGFECYC 337
C G +C CR GF ++ +C++ G CQ C + G C C
Sbjct: 171 ICRETPKGGIACECRPGFELTKNQ-------RDCKLTCNYGNGGCQHTCDDTEQGPRCGC 223
Query: 338 SEGHELEADGISC 350
L DG +C
Sbjct: 224 HIKFVLHTDGKTC 236
Score = 30.4 bits (67), Expect = 6.4
Identities = 21/88 (23%), Positives = 27/88 (30%), Gaps = 37/88 (42%)
Query: 300 FRPAEDDPHRCVD-TDECQIAGVCQQM--------------------------------- 325
+ A D CV+ TD C I +CQ
Sbjct: 23 YSKAAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDGKHCKDVDECEREDNAGC 82
Query: 326 ---CVNYVGGFECYCSEGHELEADGISC 350
CVN G + C C +G L DG +C
Sbjct: 83 VHDCVNIPGNYRCTCYDGFHLAHDGHNC 110
>gi|19743803 fibulin 5 precursor [Homo sapiens]
Length = 448
Score = 81.3 bits (199), Expect = 3e-15
Identities = 45/119 (37%), Positives = 56/119 (47%), Gaps = 5/119 (4%)
Query: 235 CSPDNGGCEHE--CVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGY 292
C+ D+ C C+ +G +C CT+G+ L D C C+Q C P Y
Sbjct: 131 CATDSHQCNPTQICIN-TEGGYTCSCTDGYWLLEGQCLDIDECRYGYCQQLCA-NVPGSY 188
Query: 293 SCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISCS 351
SC C GF ED C D +EC C Q CVN G F C C G+ELE DG+ CS
Sbjct: 189 SCTCNPGFTLNEDG-RSCQDVNECATENPCVQTCVNTYGSFICRCDPGYELEEDGVHCS 246
Score = 76.6 bits (187), Expect = 8e-14
Identities = 47/115 (40%), Positives = 56/115 (48%), Gaps = 7/115 (6%)
Query: 240 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCA-QAPCEQQCEPGGPQGYSCHC 296
G C+ C V G SC C GF L DGRSC+D CA + PC Q C + C C
Sbjct: 175 GYCQQLCAN-VPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQTCV-NTYGSFICRC 232
Query: 297 RLGFRPAEDDPHRCVDTDECQIAG-VCQQMCVNYVGGFECYCSEGHELEADGISC 350
G+ ED H C D DEC + +CQ CVN G + C C G+ L D SC
Sbjct: 233 DPGYELEEDGVH-CSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRSC 286
Score = 42.7 bits (99), Expect = 0.001
Identities = 36/140 (25%), Positives = 46/140 (32%), Gaps = 57/140 (40%)
Query: 296 CRLGFRPAEDDPHRCVDTDEC----------QIA-------------------------- 319
CR G++ D+ ++CVD DEC QI
Sbjct: 113 CRFGYQM--DESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQCLDID 170
Query: 320 ----GVCQQMCVNYVGGFECYCSEGHELEADGISCSPAGAMGAQ---------------A 360
G CQQ+C N G + C C+ G L DG SC +
Sbjct: 171 ECRYGYCQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQTCVNTYGSFIC 230
Query: 361 SQDLGDELLDDGEDEEDEDE 380
D G EL +DG D DE
Sbjct: 231 RCDPGYELEEDGVHCSDMDE 250
Score = 38.9 bits (89), Expect = 0.018
Identities = 34/129 (26%), Positives = 47/129 (36%), Gaps = 41/129 (31%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGYSC 294
CS C+HECV + G C C G+ L D RSC+D +CE + ++C
Sbjct: 251 CSFSEFLCQHECVNQ-PGTYFCSCPPGYILLDDNRSCQD-------INECE---HRNHTC 299
Query: 295 HCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECY----CSEGHELEADGISC 350
+ QQ C N GGF+C C E + +D
Sbjct: 300 N--------------------------LQQTCYNLQGGFKCIDPIRCEEPYLRISDNRCM 333
Query: 351 SPAGAMGAQ 359
PA G +
Sbjct: 334 CPAENPGCR 342
Score = 30.8 bits (68), Expect = 4.9
Identities = 20/55 (36%), Positives = 26/55 (47%), Gaps = 5/55 (9%)
Query: 284 CEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQ-IAGVCQ--QMCVNYVGGFEC 335
C P P C GF + +C+D DEC+ I C+ MCVN GG+ C
Sbjct: 16 CLPS-PGNAQAQCTNGF-DLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLC 68
>gi|239751395 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 306
Score = 81.3 bits (199), Expect = 3e-15
Identities = 65/279 (23%), Positives = 121/279 (43%), Gaps = 24/279 (8%)
Query: 398 MEPTQPPDFALAYRPSFPEDREPQIPYPEPTWPPPLSAPRVPYHSSVLSVTRPVVVSATH 457
+ P+ PP + P+ P + P S P + S+ +P++ ++
Sbjct: 42 LTPSSPPTLTPSNTPTLTPSNTPTLT--------PSSTPTLTPSSTPTLTPQPILTRSST 93
Query: 458 PTLPSAHQPPVIPATHPALSRDHQIPVIAANYPDLPSAYQPGILSVSHSAQPPAHQPPMI 517
PTL + P + P+ P L+ + + +N P L + P + S P+ +P +
Sbjct: 94 PTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILT 153
Query: 518 STKYPELFPAHQSPMFPDTRVAGTQTTTHLPGIPPNHAPLVTTLGAQLPPQAPDALVLRT 577
+ P L P+ + + + T T + P + P+ P +T + P P + + T
Sbjct: 154 RSSTPTLTPSSRPILTRSS--TPTLTPSSTPTLTPSSTPTLTP--SSTPTLTPSSRPILT 209
Query: 578 QATQLPIIPTAQPSLTTTSRSPVSPAH-----QISVPAATQPAALPTLLPSQSPTNQTSP 632
+++ + P+++P LT +S ++P+ + S P T P++ PTL PS +PT T
Sbjct: 210 RSSTPTLTPSSRPILTPSSTPTLTPSSRPILTRSSTPTLT-PSSTPTLTPSNTPT-LTPS 267
Query: 633 ISPTHPHSKAPQIPREDGPSPKLALWLPSPAPTAAPTAL 671
+PT S P + P+ PS PT P++L
Sbjct: 268 NTPTLTPSNTPTLTPSSTPT-----LTPSSTPTLTPSSL 301
Score = 73.6 bits (179), Expect = 7e-13
Identities = 60/253 (23%), Positives = 110/253 (43%), Gaps = 18/253 (7%)
Query: 400 PTQPPDFALAYRPSFPEDREPQ-------IPYPEPTWPPPLSAPRVPYHSSVLSVTRPVV 452
PT P PS PQ P P+ PP L+ P ++ P +
Sbjct: 64 PTLTPSSTPTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTP---TLTPSNTPTL 120
Query: 453 VSATHPTLPSAHQPPVIPATHPALSRDHQIPVIAANYPDLPSAYQPGILSVSHSAQPPAH 512
+ PTL + P + P++ P L+ + + ++ P L + +P + S P+
Sbjct: 121 TPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPSS 180
Query: 513 QPPMISTKYPELFPAHQSPMFPDTRVAGTQTTTHLPGIPPNHAPLVTTLGAQLPPQAPDA 572
P + + P L P+ + P +R T+++T P + P+ P++T + P P +
Sbjct: 181 TPTLTPSSTPTLTPSSTPTLTPSSRPILTRSST--PTLTPSSRPILTP--SSTPTLTPSS 236
Query: 573 LVLRTQATQLPIIPTAQPSLTTTSRSPVSPAHQISVPAATQPAALPTLLPSQSPTNQTSP 632
+ T+++ + P++ P+LT ++ ++P++ P T P+ PTL PS +PT S
Sbjct: 237 RPILTRSSTPTLTPSSTPTLTPSNTPTLTPSN---TPTLT-PSNTPTLTPSSTPTLTPSS 292
Query: 633 ISPTHPHSKAPQI 645
P S Q+
Sbjct: 293 TPTLTPSSLWHQV 305
Score = 69.7 bits (169), Expect = 9e-12
Identities = 56/231 (24%), Positives = 97/231 (41%), Gaps = 20/231 (8%)
Query: 458 PTLPSAHQPPVIPATHPALSRDHQIPVIAANYPDLPSAYQPGILSVSHSAQPPAHQPPMI 517
PTL + P + P++ P L+ Q + ++ P L + P + + P++ P +
Sbjct: 8 PTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLT 67
Query: 518 STKYPELFPAHQSPMFPDTRVAGTQTTTHLPGIPPNHAP----------LVTTLGAQLPP 567
+ P L P+ + P + + T T P PP P T + P
Sbjct: 68 PSSTPTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTPT 127
Query: 568 QAPDALVLRTQATQLPIIPTAQPSLTTTSRSPVSPAH-----QISVPAATQPAALPTLLP 622
P + T ++ + P+++P LT +S ++P+ + S P T P++ PTL P
Sbjct: 128 LTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLT-PSSTPTLTP 186
Query: 623 SQSPTNQTSPISPTHPHSKAPQIPREDGPS---PKLALWLPSPAPTAAPTA 670
S +PT T +PT S P + R P+ + PS PT P++
Sbjct: 187 SSTPT-LTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSS 236
Score = 57.4 bits (137), Expect = 5e-08
Identities = 51/195 (26%), Positives = 88/195 (45%), Gaps = 22/195 (11%)
Query: 487 ANYPDLPSAYQPGILSVSHSAQPPAHQPPMISTKYPELFPAHQSPMFPDTRVAGTQTTTH 546
+N P L + P + S P+ QP + + P L P+ + P T T ++
Sbjct: 5 SNTPTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSN--TPTLTPSN 62
Query: 547 LPGIPPNHAPLVTTLGAQLPPQAPDALVLRTQATQLPIIPTAQPSLTTTSRSPVSPAHQI 606
P + P+ P +T + P P ++ R+ L P++ P+LT ++ ++P++
Sbjct: 63 TPTLTPSSTPTLTP--SSTPTLTPQPILTRSSTPTL--TPSSPPTLTPSNTPTLTPSNTP 118
Query: 607 SV-PAAT---QPAALPTLLPSQSPTNQTS--PI-----SPTHPHSKAPQIPREDGPSPKL 655
++ P+ T P++ PTL PS +PT S PI +PT S P + R P+
Sbjct: 119 TLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPT--- 175
Query: 656 ALWLPSPAPTAAPTA 670
PS PT P++
Sbjct: 176 --LTPSSTPTLTPSS 188
Score = 36.2 bits (82), Expect = 0.12
Identities = 26/89 (29%), Positives = 42/89 (47%), Gaps = 10/89 (11%)
Query: 584 IIPTAQPSLTTTSRSPVSPAHQISVPAATQP----AALPTLLPSQSPTNQTSPISPTHPH 639
+ P+ P+LT +S ++P+ ++ ++QP ++ PTL PS PT T +PT
Sbjct: 2 LTPSNTPTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPT-LTPSNTPTLTP 60
Query: 640 SKAPQIPREDGPSPKLALWLPSPAPTAAP 668
S P + P+ PS PT P
Sbjct: 61 SNTPTLTPSSTPT-----LTPSSTPTLTP 84
>gi|239745904 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 306
Score = 81.3 bits (199), Expect = 3e-15
Identities = 65/279 (23%), Positives = 121/279 (43%), Gaps = 24/279 (8%)
Query: 398 MEPTQPPDFALAYRPSFPEDREPQIPYPEPTWPPPLSAPRVPYHSSVLSVTRPVVVSATH 457
+ P+ PP + P+ P + P S P + S+ +P++ ++
Sbjct: 42 LTPSSPPTLTPSNTPTLTPSNTPTLT--------PSSTPTLTPSSTPTLTPQPILTRSST 93
Query: 458 PTLPSAHQPPVIPATHPALSRDHQIPVIAANYPDLPSAYQPGILSVSHSAQPPAHQPPMI 517
PTL + P + P+ P L+ + + +N P L + P + S P+ +P +
Sbjct: 94 PTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILT 153
Query: 518 STKYPELFPAHQSPMFPDTRVAGTQTTTHLPGIPPNHAPLVTTLGAQLPPQAPDALVLRT 577
+ P L P+ + + + T T + P + P+ P +T + P P + + T
Sbjct: 154 RSSTPTLTPSSRPILTRSS--TPTLTPSSTPTLTPSSTPTLTP--SSTPTLTPSSRPILT 209
Query: 578 QATQLPIIPTAQPSLTTTSRSPVSPAH-----QISVPAATQPAALPTLLPSQSPTNQTSP 632
+++ + P+++P LT +S ++P+ + S P T P++ PTL PS +PT T
Sbjct: 210 RSSTPTLTPSSRPILTPSSTPTLTPSSRPILTRSSTPTLT-PSSTPTLTPSNTPT-LTPS 267
Query: 633 ISPTHPHSKAPQIPREDGPSPKLALWLPSPAPTAAPTAL 671
+PT S P + P+ PS PT P++L
Sbjct: 268 NTPTLTPSNTPTLTPSSTPT-----LTPSSTPTLTPSSL 301
Score = 73.6 bits (179), Expect = 7e-13
Identities = 60/253 (23%), Positives = 110/253 (43%), Gaps = 18/253 (7%)
Query: 400 PTQPPDFALAYRPSFPEDREPQ-------IPYPEPTWPPPLSAPRVPYHSSVLSVTRPVV 452
PT P PS PQ P P+ PP L+ P ++ P +
Sbjct: 64 PTLTPSSTPTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTP---TLTPSNTPTL 120
Query: 453 VSATHPTLPSAHQPPVIPATHPALSRDHQIPVIAANYPDLPSAYQPGILSVSHSAQPPAH 512
+ PTL + P + P++ P L+ + + ++ P L + +P + S P+
Sbjct: 121 TPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPSS 180
Query: 513 QPPMISTKYPELFPAHQSPMFPDTRVAGTQTTTHLPGIPPNHAPLVTTLGAQLPPQAPDA 572
P + + P L P+ + P +R T+++T P + P+ P++T + P P +
Sbjct: 181 TPTLTPSSTPTLTPSSTPTLTPSSRPILTRSST--PTLTPSSRPILTP--SSTPTLTPSS 236
Query: 573 LVLRTQATQLPIIPTAQPSLTTTSRSPVSPAHQISVPAATQPAALPTLLPSQSPTNQTSP 632
+ T+++ + P++ P+LT ++ ++P++ P T P+ PTL PS +PT S
Sbjct: 237 RPILTRSSTPTLTPSSTPTLTPSNTPTLTPSN---TPTLT-PSNTPTLTPSSTPTLTPSS 292
Query: 633 ISPTHPHSKAPQI 645
P S Q+
Sbjct: 293 TPTLTPSSLWHQV 305
Score = 69.7 bits (169), Expect = 9e-12
Identities = 56/231 (24%), Positives = 97/231 (41%), Gaps = 20/231 (8%)
Query: 458 PTLPSAHQPPVIPATHPALSRDHQIPVIAANYPDLPSAYQPGILSVSHSAQPPAHQPPMI 517
PTL + P + P++ P L+ Q + ++ P L + P + + P++ P +
Sbjct: 8 PTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLT 67
Query: 518 STKYPELFPAHQSPMFPDTRVAGTQTTTHLPGIPPNHAP----------LVTTLGAQLPP 567
+ P L P+ + P + + T T P PP P T + P
Sbjct: 68 PSSTPTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTPT 127
Query: 568 QAPDALVLRTQATQLPIIPTAQPSLTTTSRSPVSPAH-----QISVPAATQPAALPTLLP 622
P + T ++ + P+++P LT +S ++P+ + S P T P++ PTL P
Sbjct: 128 LTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLT-PSSTPTLTP 186
Query: 623 SQSPTNQTSPISPTHPHSKAPQIPREDGPS---PKLALWLPSPAPTAAPTA 670
S +PT T +PT S P + R P+ + PS PT P++
Sbjct: 187 SSTPT-LTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSS 236
Score = 57.4 bits (137), Expect = 5e-08
Identities = 51/195 (26%), Positives = 88/195 (45%), Gaps = 22/195 (11%)
Query: 487 ANYPDLPSAYQPGILSVSHSAQPPAHQPPMISTKYPELFPAHQSPMFPDTRVAGTQTTTH 546
+N P L + P + S P+ QP + + P L P+ + P T T ++
Sbjct: 5 SNTPTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSN--TPTLTPSN 62
Query: 547 LPGIPPNHAPLVTTLGAQLPPQAPDALVLRTQATQLPIIPTAQPSLTTTSRSPVSPAHQI 606
P + P+ P +T + P P ++ R+ L P++ P+LT ++ ++P++
Sbjct: 63 TPTLTPSSTPTLTP--SSTPTLTPQPILTRSSTPTL--TPSSPPTLTPSNTPTLTPSNTP 118
Query: 607 SV-PAAT---QPAALPTLLPSQSPTNQTS--PI-----SPTHPHSKAPQIPREDGPSPKL 655
++ P+ T P++ PTL PS +PT S PI +PT S P + R P+
Sbjct: 119 TLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPT--- 175
Query: 656 ALWLPSPAPTAAPTA 670
PS PT P++
Sbjct: 176 --LTPSSTPTLTPSS 188
Score = 36.2 bits (82), Expect = 0.12
Identities = 26/89 (29%), Positives = 42/89 (47%), Gaps = 10/89 (11%)
Query: 584 IIPTAQPSLTTTSRSPVSPAHQISVPAATQP----AALPTLLPSQSPTNQTSPISPTHPH 639
+ P+ P+LT +S ++P+ ++ ++QP ++ PTL PS PT T +PT
Sbjct: 2 LTPSNTPTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPT-LTPSNTPTLTP 60
Query: 640 SKAPQIPREDGPSPKLALWLPSPAPTAAP 668
S P + P+ PS PT P
Sbjct: 61 SNTPTLTPSSTPT-----LTPSSTPTLTP 84
>gi|120587029 signal peptide, CUB domain, EGF-like 1 [Homo sapiens]
Length = 988
Score = 80.5 bits (197), Expect = 5e-15
Identities = 42/121 (34%), Positives = 59/121 (48%), Gaps = 8/121 (6%)
Query: 227 GPLCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCA--QAPCEQ 282
G C+ T C+ +NGGC+ C + G V C C GF L DG++C+D C C+
Sbjct: 238 GRTCIET-CAVNNGGCDRTCKDTATG-VRCSCPVGFTLQPDGKTCKDINECLVNNGGCDH 295
Query: 283 QCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHE 342
C + C CR G++ D+ C D DEC C +C+N G F+C C G+
Sbjct: 296 FCR-NTVGSFECGCRKGYKLLTDE-RTCQDIDECSFERTCDHICINSPGSFQCLCHRGYI 353
Query: 343 L 343
L
Sbjct: 354 L 354
Score = 79.3 bits (194), Expect = 1e-14
Identities = 44/124 (35%), Positives = 60/124 (48%), Gaps = 8/124 (6%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCA-QAPCEQQCEPGGPQG 291
C +NGGC+H C V G C C +G++L D R+C+D C+ + C+ C P
Sbjct: 286 CLVNNGGCDHFCRNTV-GSFECGCRKGYKLLTDERTCQDIDECSFERTCDHICI-NSPGS 343
Query: 292 YSCHCRLGFRPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGGFECYCSEGHELEADGISC 350
+ C C G+ C D DEC ++ G C Q CVN G +EC C G L +G C
Sbjct: 344 FQCLCHRGY--ILYGTTHCGDVDECSMSNGSCDQGCVNTKGSYECVCPPGRRLHWNGKDC 401
Query: 351 SPAG 354
G
Sbjct: 402 VETG 405
Score = 69.7 bits (169), Expect = 9e-12
Identities = 47/161 (29%), Positives = 63/161 (39%), Gaps = 44/161 (27%)
Query: 232 GTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLA-------------------------- 265
G C + GC H C E G V+C C GF LA
Sbjct: 163 GMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDT 222
Query: 266 -------------ADGRSCEDPCA--QAPCEQQCEPGGPQGYSCHCRLGFRPAEDDPHRC 310
+DGR+C + CA C++ C+ G C C +GF + D C
Sbjct: 223 GPTCGCHQKYALHSDGRTCIETCAVNNGGCDRTCKDTA-TGVRCSCPVGF-TLQPDGKTC 280
Query: 311 VDTDECQI-AGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
D +EC + G C C N VG FEC C +G++L D +C
Sbjct: 281 KDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTC 321
Score = 68.6 bits (166), Expect = 2e-11
Identities = 43/126 (34%), Positives = 56/126 (44%), Gaps = 16/126 (12%)
Query: 235 CSPDNGGCEHECV-EEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGG----- 288
CS C + + + C C G++ +G+ CED CE GG
Sbjct: 37 CSEGTDDCHIDAICQNTPKSYKCLCKPGYK--GEGKQCEDI---DECENDYYNGGCVHEC 91
Query: 289 ---PQGYSCHCRLGFRPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGGFECYCSEGHELE 344
P Y C C GF A D H C+D DECQ G CQQ+CVN +G +EC C G L
Sbjct: 92 INIPGNYRCTCFDGFMLAHDG-HNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLS 150
Query: 345 ADGISC 350
+ +C
Sbjct: 151 DNQHTC 156
Score = 56.6 bits (135), Expect = 8e-08
Identities = 49/177 (27%), Positives = 71/177 (40%), Gaps = 28/177 (15%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQA--------PCEQQCEP 286
C +NGGC+ CV + G C+C GF L+ + +C + C C
Sbjct: 121 CQDNNGGCQQICVNAM-GSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRE 179
Query: 287 GGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGGFECYCSEGHELEA 345
G +C CR GF A++ C T C G CQ C + G C C + + L +
Sbjct: 180 TPKGGVACDCRPGFDLAQNQKD-CTLT--CNYGNGGCQHSCEDTDTGPTCGCHQKYALHS 236
Query: 346 DGISCSPAGAM--------------GAQASQDLGDELLDDGEDEEDEDEAWKAFNGG 388
DG +C A+ G + S +G L DG+ +D +E NGG
Sbjct: 237 DGRTCIETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINEC-LVNNGG 292
>gi|4557617 growth arrest-specific 6 isoform 1 precursor [Homo
sapiens]
Length = 678
Score = 79.3 bits (194), Expect = 1e-14
Identities = 48/122 (39%), Positives = 66/122 (54%), Gaps = 10/122 (8%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCA--QAPCEQQCEPGGPQ 290
CS +NGGC C + G C C GF L++DGR+C+ D CA +A E +C+ P
Sbjct: 160 CSQENGGCLQICHNK-PGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCK-NLPG 217
Query: 291 GYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCS--EGHELEADGI 348
YSC C GF + + C D DEC + G C+Q+CVN G + C+C G +L D
Sbjct: 218 SYSCLCDEGFAYSSQE-KACRDVDEC-LQGRCEQVCVNSPGSYTCHCDGRGGLKLSQDMD 275
Query: 349 SC 350
+C
Sbjct: 276 TC 277
Score = 52.8 bits (125), Expect = 1e-06
Identities = 40/142 (28%), Positives = 57/142 (40%), Gaps = 14/142 (9%)
Query: 202 QCQAGRGASL-LCVKQP-------EGGVGWSRAGPLCLGTGCSPDNGGCEHECVEEVDGH 253
+C G L +C +P G S G C D+ C + + G
Sbjct: 159 ECSQENGGCLQICHNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNLPGS 218
Query: 254 VSCRCTEGFRLAADGRSCE--DPCAQAPCEQQCEPGGPQGYSCHC--RLGFRPAEDDPHR 309
SC C EGF ++ ++C D C Q CEQ C P Y+CHC R G + ++ D
Sbjct: 219 YSCLCDEGFAYSSQEKACRDVDECLQGRCEQVC-VNSPGSYTCHCDGRGGLKLSQ-DMDT 276
Query: 310 CVDTDECQIAGVCQQMCVNYVG 331
C D C V + + Y+G
Sbjct: 277 CEDILPCVPFSVAKSVKSLYLG 298
Score = 45.1 bits (105), Expect = 2e-04
Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 8/82 (9%)
Query: 273 DPCAQAPCEQQCEPGGPQ---GYSCHCRLGFRPAEDDPHRCVDTDEC-QIAGVCQQMCVN 328
D C PC+++ + C C+ G+ D D +EC Q G C Q+C N
Sbjct: 118 DQCTPNPCDRKGTQACQDLMGNFFCLCKAGWGGRLCDK----DVNECSQENGGCLQICHN 173
Query: 329 YVGGFECYCSEGHELEADGISC 350
G F C C G EL +DG +C
Sbjct: 174 KPGSFHCSCHSGFELSSDGRTC 195
>gi|13699830 matrilin 4 isoform 1 precursor [Homo sapiens]
Length = 581
Score = 79.0 bits (193), Expect = 2e-14
Identities = 49/130 (37%), Positives = 62/130 (47%), Gaps = 12/130 (9%)
Query: 229 LCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCA--QAPCEQQC 284
LC C+ GCEH CV G C C GF L D RSC D C+ C+ +C
Sbjct: 213 LCAIDLCAEGTHGCEHHCVNS-PGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHSCQHEC 271
Query: 285 --EPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQ-IAGVCQQMCVNYVGGFECYCSEGH 341
PGGP+ CHCR G + D C D C + C+ CV+ + C C EG
Sbjct: 272 VSTPGGPR---CHCREG-HDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGR 327
Query: 342 ELEADGISCS 351
+L+ADG SC+
Sbjct: 328 QLQADGKSCN 337
Score = 65.1 bits (157), Expect = 2e-10
Identities = 37/93 (39%), Positives = 45/93 (48%), Gaps = 6/93 (6%)
Query: 262 FRLAADGRSCE-DPCAQAP--CEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQI 318
F L R C D CA+ CE C P Y CHC++GF + D C D C
Sbjct: 205 FGLQFQSRLCAIDLCAEGTHGCEHHCV-NSPGSYFCHCQVGF-VLQQDQRSCRAIDYCSF 262
Query: 319 AG-VCQQMCVNYVGGFECYCSEGHELEADGISC 350
CQ CV+ GG C+C EGH+L+ DG SC
Sbjct: 263 GNHSCQHECVSTPGGPRCHCREGHDLQPDGRSC 295
>gi|126012573 low density lipoprotein-related protein 2 [Homo sapiens]
Length = 4655
Score = 78.6 bits (192), Expect = 2e-14
Identities = 45/123 (36%), Positives = 49/123 (39%), Gaps = 40/123 (32%)
Query: 228 PLCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPG 287
PLC G CS NGGC HECV+E
Sbjct: 1346 PLCNGNSCSDFNGGCTHECVQE-------------------------------------- 1367
Query: 288 GPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADG 347
P G C C LGF A D C D DEC I G C Q C N G F C C G+ LE+DG
Sbjct: 1368 -PFGAKCLCPLGFLLANDSK-TCEDIDECDILGSCSQHCYNMRGSFRCSCDTGYMLESDG 1425
Query: 348 ISC 350
+C
Sbjct: 1426 RTC 1428
Score = 66.6 bits (161), Expect = 8e-11
Identities = 38/116 (32%), Positives = 54/116 (46%), Gaps = 7/116 (6%)
Query: 235 CSPDNGGCEHE--CV---EEVDGHVSCRCTEGFRLAADGRSCEDP-CAQAPCEQQCEPGG 288
CSP C C+ + DG + C E + G+ C C+ C+ QC
Sbjct: 266 CSPREWSCPESGRCISIYKVCDGILDCPGREDENNTSTGKYCSMTLCSALNCQYQCHET- 324
Query: 289 PQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELE 344
P G +C C G+ +D CV+ D+CQI G+C Q C + G C+C EG+ LE
Sbjct: 325 PYGGACFCPPGYIINHNDSRTCVEFDDCQIWGICDQKCESRPGRHLCHCEEGYILE 380
Score = 64.3 bits (155), Expect = 4e-10
Identities = 31/86 (36%), Positives = 42/86 (48%), Gaps = 2/86 (2%)
Query: 272 EDPCAQAPCEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVG 331
E CA+ CEQ C G+ C C GF D C+D +EC+ G C Q C N G
Sbjct: 3967 ERTCAENICEQNCTQLNEGGFICSCTAGFETNVFDRTSCLDINECEQFGTCPQHCRNTKG 4026
Query: 332 GFECYCSEGHELEAD--GISCSPAGA 355
+EC C++G +D G C+ G+
Sbjct: 4027 SYECVCADGFTSMSDRPGKRCAAEGS 4052
Score = 60.5 bits (145), Expect = 6e-09
Identities = 46/156 (29%), Positives = 65/156 (41%), Gaps = 11/156 (7%)
Query: 203 CQAGRGAS--LLCVKQPEGGVGWSRAGPLCLGTG--CSPDNGGCEH-ECVE--EVDGHVS 255
CQ GR S +C + + G G LC C P C++ C+E ++ H+
Sbjct: 3039 CQNGRCISKTFVCDEDNDCGDGSDELMHLCHTPEPTCPPHEFKCDNGRCIEMMKLCNHLD 3098
Query: 256 CRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDE 315
C DP C+ C Y C CR G++ D CVD DE
Sbjct: 3099 DCLDNSDEKGCGINECHDPSISG-CDHNCTDTLTSFY-CSCRPGYK-LMSDKRTCVDIDE 3155
Query: 316 C-QIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
C ++ VC Q C N +G + C C+ G+ E DG +C
Sbjct: 3156 CTEMPFVCSQKCENVIGSYICKCAPGYLREPDGKTC 3191
Score = 38.9 bits (89), Expect = 0.018
Identities = 29/97 (29%), Positives = 37/97 (38%), Gaps = 19/97 (19%)
Query: 239 NGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCE-DPCAQAPCEQ------QCEPGG--P 289
NG C H C + C C G RLA++ +CE DP + P EQ C+ G P
Sbjct: 981 NGDCSHFCFPVPNFQRVCGCPYGMRLASNHLTCEGDPTNEPPTEQCGLFSFPCKNGRCVP 1040
Query: 290 QGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMC 326
Y C D C D + Q+ G C
Sbjct: 1041 NYYLC----------DGVDDCHDNSDEQLCGTLNNTC 1067
Score = 38.9 bits (89), Expect = 0.018
Identities = 16/38 (42%), Positives = 20/38 (52%)
Query: 234 GCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSC 271
GCS + C+ C+ G SC C GF+L D RSC
Sbjct: 2021 GCSNNMNACQQICLPVPGGLFSCACATGFKLNPDNRSC 2058
Score = 38.5 bits (88), Expect = 0.023
Identities = 27/74 (36%), Positives = 29/74 (39%), Gaps = 6/74 (8%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRL-AADGRSCED--PCAQ-APCEQQCEPGGPQGYSCHCR 297
CE C + +G C CT GF D SC D C Q C Q C Y C C
Sbjct: 3975 CEQNCTQLNEGGFICSCTAGFETNVFDRTSCLDINECEQFGTCPQHCR-NTKGSYECVCA 4033
Query: 298 LGFRPAEDDP-HRC 310
GF D P RC
Sbjct: 4034 DGFTSMSDRPGKRC 4047
Score = 37.4 bits (85), Expect = 0.052
Identities = 19/42 (45%), Positives = 23/42 (54%), Gaps = 5/42 (11%)
Query: 235 CSPDNGGCEHECV----EEVDG-HVSCRCTEGFRLAADGRSC 271
C +NGGCE CV + DG C+CT GF+L D R C
Sbjct: 663 CKDNNGGCEQVCVLSHRTDNDGLGFRCKCTFGFQLDTDERHC 704
Score = 36.6 bits (83), Expect = 0.089
Identities = 16/32 (50%), Positives = 20/32 (62%), Gaps = 1/32 (3%)
Query: 322 CQQMCVNYVGG-FECYCSEGHELEADGISCSP 352
CQQ+C+ GG F C C+ G +L D SCSP
Sbjct: 2029 CQQICLPVPGGLFSCACATGFKLNPDNRSCSP 2060
Score = 33.1 bits (74), Expect = 0.98
Identities = 38/172 (22%), Positives = 59/172 (34%), Gaps = 37/172 (21%)
Query: 235 CSPDNGGCEHECVEEVDGH-VSCRCTEGFR-------------------LAADGRSCEDP 274
C +NGGC H C+ + G +C C + FR L A+ C
Sbjct: 3469 CGTNNGGCSHLCLIKPGGKGFTCECPDDFRTLQLSGSTYCMPMCSSTQFLCANNEKCIPI 3528
Query: 275 CAQAPCEQQCEPGGPQGYSC---HCRLGFRPAEDDPHRCVDTDECQIAGVC--QQMCVNY 329
+ ++ C G + C CRLG +C D + +C Q C +
Sbjct: 3529 WWKCDGQKDCSDGSDELALCPQRFCRLG-------QFQCSDGNCTSPQTLCNAHQNCPDG 3581
Query: 330 VGGFECYCSEGHELEADGISCSPAGAMGAQASQDLGDELLDDGEDEEDEDEA 381
C E H +++ C+ + D +D ED DED +
Sbjct: 3582 SDEDRLLC-ENHHCDSNEWQCANKRCIPESWQCD----TFNDCEDNSDEDSS 3628
Score = 30.0 bits (66), Expect = 8.3
Identities = 15/38 (39%), Positives = 19/38 (50%), Gaps = 2/38 (5%)
Query: 235 CSPDNGGCEHECVEEVDGHV-SCRCTEGFRLAADGRSC 271
C +NGGC H C H C C G L +DG++C
Sbjct: 2346 CLENNGGCSHLCFALPGLHTPKCDCAFG-TLQSDGKNC 2382
>gi|190343004 EGF-containing fibulin-like extracellular matrix
protein 2 [Homo sapiens]
Length = 443
Score = 76.6 bits (187), Expect = 8e-14
Identities = 52/172 (30%), Positives = 78/172 (45%), Gaps = 22/172 (12%)
Query: 222 GWSRAGPLCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQ-A 278
G+ + GP C+ C+H CV + G C+C GF+L + RSC D C A
Sbjct: 154 GYRKIGPECVDID-ECRYRYCQHRCVN-LPGSFRCQCEPGFQLGPNNRSCVDVNECDMGA 211
Query: 279 PCEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAG-VCQQMCVNYVGGFECYC 337
PCEQ+C + C C G+ D C D DEC + +CQ CVN G F C+C
Sbjct: 212 PCEQRCF-NSYGTFLCRCHQGYE-LHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHC 269
Query: 338 SEGHELEADGISCSPAGAMGAQASQDLGDELLDDGEDEEDEDEAWKAFNGGW 389
+G++L + + QD+ + + G + E + F+GG+
Sbjct: 270 PQGYQL------------LATRLCQDIDE--CESGAHQCSEAQTCVNFHGGY 307
Score = 74.3 bits (181), Expect = 4e-13
Identities = 38/113 (33%), Positives = 52/113 (46%), Gaps = 7/113 (6%)
Query: 244 HECVEEVDGH-----VSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGYSCHCRL 298
H+C D H C C +G+R D C C+ +C P + C C
Sbjct: 132 HDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRYRYCQHRCV-NLPGSFRCQCEP 190
Query: 299 GFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISCS 351
GF+ ++ CVD +EC + C+Q C N G F C C +G+EL DG SCS
Sbjct: 191 GFQLGPNN-RSCVDVNECDMGAPCEQRCFNSYGTFLCRCHQGYELHRDGFSCS 242
Score = 59.7 bits (143), Expect = 1e-08
Identities = 39/103 (37%), Positives = 51/103 (49%), Gaps = 15/103 (14%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAP--CEQQC--EPGGPQGYSCH 295
CE C G CRC +G+ L DG SC D C+ + C+ +C EPG +SCH
Sbjct: 213 CEQRCFNSY-GTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGR---FSCH 268
Query: 296 CRLGFRPAEDDPHRCVDTDECQI-AGVCQ--QMCVNYVGGFEC 335
C G++ C D DEC+ A C Q CVN+ GG+ C
Sbjct: 269 CPQGYQLLAT--RLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 39.7 bits (91), Expect = 0.010
Identities = 37/137 (27%), Positives = 50/137 (36%), Gaps = 39/137 (28%)
Query: 240 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAP--C--EQQC--------- 284
G + EE D + C T+G+ D + C D C P C E +C
Sbjct: 23 GSASPQDSEEPDSYTEC--TDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLC 80
Query: 285 -----------------EPGGPQGYSCHCRLGFRPAEDDPHRCVDTDEC-QIAGVCQ--Q 324
P P + C G+ P DD CVD DEC Q C+ Q
Sbjct: 81 LPRSAAVINDLHGEGPPPPVPPAQHPNPCPPGYEP--DDQDSCVDVDECAQALHDCRPSQ 138
Query: 325 MCVNYVGGFECYCSEGH 341
C N G ++C C +G+
Sbjct: 139 DCHNLPGSYQCTCPDGY 155
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 76.3 bits (186), Expect = 1e-13
Identities = 49/138 (35%), Positives = 60/138 (43%), Gaps = 12/138 (8%)
Query: 222 GWSRAGPLCLGTG-CSPDNGGCE--HECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQA 278
GW G C+ CS C +CV G C C+EGF DG +C D A
Sbjct: 1398 GWIGNGIKCIDLDECSNGTHQCSINAQCVN-TPGSYRCACSEGF--TGDGFTCSDVDECA 1454
Query: 279 PCEQQCEPGG----PQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQ-QMCVNYVGGF 333
CE G P Y C C +GF PA D C D DEC +C C N G F
Sbjct: 1455 ENINLCENGQCLNVPGAYRCECEMGFTPASDS-RSCQDIDECSFQNICVFGTCNNLPGMF 1513
Query: 334 ECYCSEGHELEADGISCS 351
C C +G+EL+ G +C+
Sbjct: 1514 HCICDDGYELDRTGGNCT 1531
Score = 71.2 bits (173), Expect = 3e-12
Identities = 42/123 (34%), Positives = 58/123 (47%), Gaps = 8/123 (6%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCAQAP--CEQQCEPGGPQ 290
C NGGC+ +C +G C C+EG+ L DGRSC D C P C+ P
Sbjct: 1246 CMIMNGGCDTQCTNS-EGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPG 1304
Query: 291 GYSCHCRLGFRPAEDDPHRCVDTDECQI-AGVCQ-QMCVNYVGGFECYCSEGHELEADGI 348
Y C C GF A D C+D +EC + + +C C N G F C+C G+ ++
Sbjct: 1305 EYRCLCYDGFM-ASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTT 1363
Query: 349 SCS 351
C+
Sbjct: 1364 GCT 1366
Score = 71.2 bits (173), Expect = 3e-12
Identities = 38/114 (33%), Positives = 53/114 (46%), Gaps = 7/114 (6%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 299
C H ++ G C C GF+ + D C D C + PC Y+C C G
Sbjct: 1903 CSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPG 1962
Query: 300 FRPAEDDPHRCVDTDECQ--IAGVCQQ-MCVNYVGGFECYCSEGHELEADGISC 350
F ++ C+D DEC VC+ C N +G F+C C+EG+EL DG +C
Sbjct: 1963 FELTHNND--CLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNC 2014
Score = 68.6 bits (166), Expect = 2e-11
Identities = 47/143 (32%), Positives = 62/143 (43%), Gaps = 14/143 (9%)
Query: 220 GVGWSRAGPLCLG-TGCSPDNGGCEHE--------CVEEVDGHVSCRCTEGFRLAADGRS 270
GVG GP+ G T + C+H C+ V + C C G++ A+G
Sbjct: 475 GVGAGGQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSY-RCECNMGYKQDANGDC 533
Query: 271 CE-DPCAQAPCEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGV-CQQ-MCV 327
+ D C PC P Y C C GF+ C+D DEC GV C+ CV
Sbjct: 534 IDVDECTSNPCTNGDCVNTPGSYYCKCHAGFQRTPTK-QACIDIDECIQNGVLCKNGRCV 592
Query: 328 NYVGGFECYCSEGHELEADGISC 350
N G F+C C+ G EL DG +C
Sbjct: 593 NTDGSFQCICNAGFELTTDGKNC 615
Score = 67.4 bits (163), Expect = 5e-11
Identities = 41/130 (31%), Positives = 53/130 (40%), Gaps = 20/130 (15%)
Query: 230 CLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--------PCAQAPCE 281
C+ G NG C + DG C C GF L DG++C D C C
Sbjct: 579 CIQNGVLCKNGRCVN-----TDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCI 633
Query: 282 QQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQ-MCVNYVGGFECYCSEG 340
+ + C C+ GF A + + C D DECQ G+C C+N G F C C G
Sbjct: 634 NE-----DGSFKCICKPGFVLAPNGRY-CTDVDECQTPGICMNGHCINSEGSFRCDCPPG 687
Query: 341 HELEADGISC 350
+ DG C
Sbjct: 688 LAVGMDGRVC 697
Score = 65.1 bits (157), Expect = 2e-10
Identities = 39/111 (35%), Positives = 48/111 (43%), Gaps = 7/111 (6%)
Query: 246 CVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQG----YSCHCRLGFR 301
CV +G C C G L+ C D + + C G Y C C G++
Sbjct: 1174 CVN-TEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQ 1232
Query: 302 PAEDDPHRCVDTDECQIA-GVCQQMCVNYVGGFECYCSEGHELEADGISCS 351
A D C D DEC I G C C N G +EC CSEG+ L DG SC+
Sbjct: 1233 -ATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCA 1282
Score = 62.4 bits (150), Expect = 2e-09
Identities = 36/120 (30%), Positives = 50/120 (41%), Gaps = 5/120 (4%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPG----GPQ 290
C+ D C + E + G C C G+ A GR+C D C+ G P
Sbjct: 772 CALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPG 831
Query: 291 GYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
YSC C G+ + C D +EC+ C N +G F C CS G +L + G+ C
Sbjct: 832 SYSCTCPPGY-VFRTETETCEDINECESNPCVNGACRNNLGSFNCECSPGSKLSSTGLIC 890
Score = 61.2 bits (147), Expect = 3e-09
Identities = 42/144 (29%), Positives = 56/144 (38%), Gaps = 13/144 (9%)
Query: 220 GVGWSRAGPLCLG-------TGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCE 272
G G++ G + G C G C + G CRC GF L + R+C
Sbjct: 1055 GAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCT 1114
Query: 273 --DPCAQAP--CEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAG-VCQ-QMC 326
D C +P C P + C C G+ C+D DEC+ +C+ C
Sbjct: 1115 DIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTC 1174
Query: 327 VNYVGGFECYCSEGHELEADGISC 350
VN G F+C C GHEL C
Sbjct: 1175 VNTEGSFQCDCPLGHELSPSREDC 1198
Score = 61.2 bits (147), Expect = 3e-09
Identities = 37/124 (29%), Positives = 55/124 (44%), Gaps = 14/124 (11%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED----PCAQAPCEQQCEPGGPQ 290
CS C + C + +G C C G+ L DG++C+D Q C+ C
Sbjct: 2495 CSQSPKPCNYIC-KNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCV-NTLG 2552
Query: 291 GYSCHCRLGFRPAEDDPHRCVDTDEC----QIAGVCQQMCVNYVGGFECYCSEGHELEAD 346
G++C C GF C+D +EC + G + +C N G F C C G L+A
Sbjct: 2553 GFTCKCPPGFTQHHT---ACIDNNECGSQPSLCGA-KGICQNTPGSFSCECQRGFSLDAT 2608
Query: 347 GISC 350
G++C
Sbjct: 2609 GLNC 2612
Score = 60.8 bits (146), Expect = 4e-09
Identities = 38/118 (32%), Positives = 50/118 (42%), Gaps = 14/118 (11%)
Query: 239 NGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQ----GYSC 294
NG C +E G C C EG+ L DG++C D C PG Q + C
Sbjct: 1987 NGRCFNEI-----GSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRC 2041
Query: 295 HCRLGFRPAEDDPHRCVDTDEC-QIAGVCQ-QMCVNYVGGFECYCSEGHELEADGISC 350
C G+ E C+D +EC + +C C N GGF+C C G L +G C
Sbjct: 2042 ICPPGY---EVKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRC 2096
Score = 58.5 bits (140), Expect = 2e-08
Identities = 67/249 (26%), Positives = 82/249 (32%), Gaps = 65/249 (26%)
Query: 143 LEGSCTLAVDGYLCQFGFEGACP---ALQDEAGQAGPAVYTTPFHLVSTEFEWLPFGSVA 199
L GSCT G+ C CP L D G + T T FE G +
Sbjct: 2068 LFGSCTNTPGGFQC------LCPPGFVLSDN----GRRCFDTRQSFCFTNFE---NGKCS 2114
Query: 200 AVQCQAGRGASLLCVKQPEGGVGWSRAGPLC-------------LGTGCSP---DNGGCE 243
+ A C K P G GW LC G G P D
Sbjct: 2115 VPKAFNTTKAKCCCSKMP--GEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDV 2172
Query: 244 HECVEE-----------VDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQG- 291
+EC+E DG C C G+ L G C D +C G P G
Sbjct: 2173 NECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDT-------DECSIGNPCGN 2225
Query: 292 ---------YSCHCRLGFRPAEDDPHRCVDTDEC-QIAGVCQQMCVNYVGGFECYCSEGH 341
+ C+C GF P C D +EC Q +C C+N G +EC C G+
Sbjct: 2226 GTCTNVIGSFECNCNEGFEPGP--MMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGY 2283
Query: 342 ELEADGISC 350
L D C
Sbjct: 2284 ALREDQKMC 2292
Score = 57.8 bits (138), Expect = 4e-08
Identities = 35/117 (29%), Positives = 49/117 (41%), Gaps = 10/117 (8%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQ------GYSCH 295
C C+ G C C G+ L D + C+D A CE G + C
Sbjct: 2264 CAFRCMNTF-GSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCI 2322
Query: 296 CRLGFRPAEDDPHRCVDTDECQIA-GVCQQ-MCVNYVGGFECYCSEGHELEADGISC 350
C G D CVD +EC+ G+C+ CVN +G + C C+EG + + G C
Sbjct: 2323 CPPGMA-RRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTEC 2378
Score = 57.8 bits (138), Expect = 4e-08
Identities = 36/121 (29%), Positives = 51/121 (42%), Gaps = 7/121 (5%)
Query: 234 GCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQ--- 290
G P G + C + G SC C GF L A G +CED + +C+ G
Sbjct: 2576 GSQPSLCGAKGIC-QNTPGSFSCECQRGFSLDATGLNCED-VDECDGNHRCQHGCQNILG 2633
Query: 291 GYSCHCRLGFRPAEDDPHRCVDTDECQIAGVC-QQMCVNYVGGFECYCSEGHELEADGIS 349
GY C C G+ ++CVD +EC C C N +G ++C C G + +
Sbjct: 2634 GYRCGCPQGYIQ-HYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSA 2692
Query: 350 C 350
C
Sbjct: 2693 C 2693
Score = 57.4 bits (137), Expect = 5e-08
Identities = 37/115 (32%), Positives = 50/115 (43%), Gaps = 9/115 (7%)
Query: 235 CSPDNGGCEH--ECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAP--CEQQCEPGG 288
CS + C+ +C+ G C C GF+L+ +G +C D C + P C
Sbjct: 1854 CSNGDNLCQRNADCINS-PGSYRCECAAGFKLSPNG-ACVDRNECLEIPNVCSHGLCVDL 1911
Query: 289 PQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHEL 343
Y C C GF+ A D C+D DEC+ C N VG + C C G EL
Sbjct: 1912 QGSYQCICHNGFK-ASQDQTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPGFEL 1965
Score = 56.6 bits (135), Expect = 8e-08
Identities = 38/127 (29%), Positives = 52/127 (40%), Gaps = 13/127 (10%)
Query: 230 CLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQ--APCEQQCE 285
C C+ NG C + G C+C GF+ ++C D C Q C+
Sbjct: 539 CTSNPCT--NGDCVN-----TPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRC 591
Query: 286 PGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQ-MCVNYVGGFECYCSEGHELE 344
+ C C GF D + CVD DEC +C MC+N G F+C C G L
Sbjct: 592 VNTDGSFQCICNAGFELTTDGKN-CVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLA 650
Query: 345 ADGISCS 351
+G C+
Sbjct: 651 PNGRYCT 657
Score = 56.6 bits (135), Expect = 8e-08
Identities = 32/111 (28%), Positives = 46/111 (41%), Gaps = 7/111 (6%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFR----LAADGRSCEDPCAQAPCEQQCEPGGPQ 290
C C+ CV + G +C+C GF D C + + C+ P
Sbjct: 2536 CQTKQHNCQFLCVNTLGGF-TCKCPPGFTQHHTACIDNNECGSQPSLCGAKGICQ-NTPG 2593
Query: 291 GYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGH 341
+SC C+ GF + C D DEC CQ C N +GG+ C C +G+
Sbjct: 2594 SFSCECQRGFS-LDATGLNCEDVDECDGNHRCQHGCQNILGGYRCGCPQGY 2643
Score = 55.8 bits (133), Expect = 1e-07
Identities = 38/120 (31%), Positives = 51/120 (42%), Gaps = 5/120 (4%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCA-QAPCEQQCEPGGPQG 291
C+ + CE+ V G C C GF A+D RSC+ D C+ Q C P
Sbjct: 1453 CAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGTCNNLPGM 1512
Query: 292 YSCHCRLGFRPAEDDPHRCVDTDECQIAGVC-QQMCVNYVGGFECYCSEGHELEADGISC 350
+ C C G+ + C D DEC C +CVN G +EC C +L G+ C
Sbjct: 1513 FHCICDDGYE-LDRTGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGC 1571
Score = 54.7 bits (130), Expect = 3e-07
Identities = 34/87 (39%), Positives = 40/87 (45%), Gaps = 14/87 (16%)
Query: 258 CTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQ 317
CT+ A GR+ PC P + Q CR GF P C D DECQ
Sbjct: 234 CTKTLCCATIGRAWGHPCEMCPAQPQ-----------PCRRGFIP-NIRTGACQDVDECQ 281
Query: 318 -IAGVCQQ-MCVNYVGGFECYCSEGHE 342
I G+CQ C+N VG FEC C GH+
Sbjct: 282 AIPGICQGGNCINTVGSFECRCPAGHK 308
Score = 54.7 bits (130), Expect = 3e-07
Identities = 44/164 (26%), Positives = 62/164 (37%), Gaps = 24/164 (14%)
Query: 193 LPFGSVAAVQCQAGRGASLLCVKQP---EGGVGWSRAGPLCLGTGCSPDNGGCEHECVEE 249
L F V CQ + L K +GG GW LC P G +++ +
Sbjct: 2385 LCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELC------PLPGTAQYKKI-- 2436
Query: 250 VDGHVSCRCTEGFRLAADGRSCEDPCAQAP--CEQQCEPGGPQGYSCHCRLGFRPAEDDP 307
C G DGR D C P C + C C++G+ +
Sbjct: 2437 --------CPHGPGYTTDGRDI-DECKVMPNLCTNGQCINTMGSFRCFCKVGYT-TDISG 2486
Query: 308 HRCVDTDEC-QIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
C+D DEC Q C +C N G ++C C G+ L+ DG +C
Sbjct: 2487 TSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTC 2530
Score = 52.0 bits (123), Expect = 2e-06
Identities = 41/157 (26%), Positives = 59/157 (37%), Gaps = 38/157 (24%)
Query: 232 GTGCSPDN------GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--------PCAQ 277
G GC +N G CE+ + G C C EGF+ ++ G C D Q
Sbjct: 2333 GEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQ 2392
Query: 278 APCE-----------QQCEPGGPQGYSCHCRLGFRPAEDD-----PH------RCVDTDE 315
C+ +C G +G+ C L P PH D DE
Sbjct: 2393 TICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDE 2452
Query: 316 CQI-AGVCQQ-MCVNYVGGFECYCSEGHELEADGISC 350
C++ +C C+N +G F C+C G+ + G SC
Sbjct: 2453 CKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSC 2489
Score = 50.8 bits (120), Expect = 5e-06
Identities = 34/123 (27%), Positives = 48/123 (39%), Gaps = 10/123 (8%)
Query: 235 CSPDNGGCEH-ECVEEVDGHVSCRCTEGFRLAADGRSCED----PCAQAPCEQQCEPGGP 289
CS + C + +CV + G C C G++ D + C D C+ QC
Sbjct: 1204 CSLSDNLCRNGKCVNMI-GTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQC-TNSE 1261
Query: 290 QGYSCHCRLGFRPAEDDPHRCVDTDECQ-IAGVCQ-QMCVNYVGGFECYCSEGHELEADG 347
Y C C G+ D C D DEC+ +C C N G + C C +G D
Sbjct: 1262 GSYECSCSEGY-ALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDM 1320
Query: 348 ISC 350
+C
Sbjct: 1321 KTC 1323
Score = 49.7 bits (117), Expect = 1e-05
Identities = 42/127 (33%), Positives = 55/127 (43%), Gaps = 12/127 (9%)
Query: 232 GTGCSPDN-GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQA-PCEQQCEPGGP 289
G GC + G C + DG +SC G ++ C A PCE C P
Sbjct: 1568 GVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCET-CPPVNS 1626
Query: 290 QGYSCHCR--LGFRPAEDDPHRCV--DTDECQ-IAGVCQQ-MCVNYVGGFECYCSEGHEL 343
Y C GFRP +P + D DECQ + G+CQ C+N G F+C C +G+ L
Sbjct: 1627 TEYYTLCPGGEGFRP---NPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYL 1683
Query: 344 EADGISC 350
D C
Sbjct: 1684 SEDTRIC 1690
Score = 48.1 bits (113), Expect = 3e-05
Identities = 49/186 (26%), Positives = 63/186 (33%), Gaps = 29/186 (15%)
Query: 208 GASLLCVKQP-------EGGVGWSRAGPLCLGTGCSPDNGGCEHECVEEVDGHVSCRCTE 260
GA +C P + G G C N C+H C + + G C C +
Sbjct: 2583 GAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHRCQHGC-QNILGGYRCGCPQ 2641
Query: 261 GF------RLAADGRSCEDP--CAQAPCEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVD 312
G+ D C +P C A C Y C C GF + C D
Sbjct: 2642 GYIQHYQWNQCVDENECSNPNACGSASCYNTLG-----SYKCACPSGFS-FDQFSSACHD 2695
Query: 313 TDECQIA-GVCQQMCVNYVGGFECYCSEGHELEADGISCSPAGAMGAQASQDLGDELLDD 371
+EC + C C N GG+ C C G+ G S MG Q L LD
Sbjct: 2696 VNECSSSKNPCNYGCSNTEGGYLCGCPPGYYRVGQGHCVS---GMGFNKGQYLS---LDT 2749
Query: 372 GEDEED 377
DEE+
Sbjct: 2750 EVDEEN 2755
Score = 43.1 bits (100), Expect = 0.001
Identities = 39/140 (27%), Positives = 51/140 (36%), Gaps = 35/140 (25%)
Query: 239 NGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED----PCAQAPCEQQCEP-------- 286
NG C + G +C C+ G +L++ G C D C + +CE
Sbjct: 863 NGACRNNL-----GSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLK 917
Query: 287 -------GGPQGYSCH-------CRLGFRPAEDDPHRCVDTDECQI-AGVCQQ-MCVNYV 330
G G C C G A C D +EC++ GVC CVN
Sbjct: 918 SECCATLGAAWGSPCERCELDTACPRGL--ARIKGVTCEDVNECEVFPGVCPNGRCVNSK 975
Query: 331 GGFECYCSEGHELEADGISC 350
G F C C EG L+ G C
Sbjct: 976 GSFHCECPEGLTLDGTGRVC 995
Score = 43.1 bits (100), Expect = 0.001
Identities = 44/192 (22%), Positives = 61/192 (31%), Gaps = 42/192 (21%)
Query: 196 GSVAAVQCQAGRGASLLCVKQPEGGVGWSRAGPLCLGTG-CSPDNGGCEHECVEEVDGHV 254
GS + CQ G S C+ P G+ C+ C D C G
Sbjct: 2025 GSCSPGTCQNLEG-SFRCICPP----GYEVKSENCIDINECDEDPNICLFGSCTNTPGGF 2079
Query: 255 SCRCTEGFRLAADGRSCEDP----------------------------CAQAPCE----- 281
C C GF L+ +GR C D C++ P E
Sbjct: 2080 QCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDP 2139
Query: 282 -QQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDEC-QIAGVCQQ-MCVNYVGGFECYCS 338
+ C + C G D +EC + G+C C+N G F C C
Sbjct: 2140 CELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECP 2199
Query: 339 EGHELEADGISC 350
G+ L+ G+ C
Sbjct: 2200 MGYNLDYTGVRC 2211
Score = 38.9 bits (89), Expect = 0.018
Identities = 41/173 (23%), Positives = 61/173 (35%), Gaps = 34/173 (19%)
Query: 210 SLLCVKQPEGGVGWSRAGPLCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGR 269
S C+ +P G + G C G C + +G C C G + DGR
Sbjct: 638 SFKCICKP--GFVLAPNGRYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGR 695
Query: 270 SCEDPCAQAPCEQQCE--------PGGPQGYSCHCR---LGF-RPAEDDPHR-------- 309
C D ++ C + PG C C GF P + P +
Sbjct: 696 VCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGL 755
Query: 310 CV----------DTDECQI-AGVCQQ-MCVNYVGGFECYCSEGHELEADGISC 350
C D +EC + +C +C N G + C C+ G+E +A G +C
Sbjct: 756 CSSGVGITVDGRDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNC 808
Score = 37.7 bits (86), Expect = 0.040
Identities = 34/116 (29%), Positives = 49/116 (42%), Gaps = 17/116 (14%)
Query: 243 EHECVEEVDGHV---SCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGYSCHCR-- 297
E EC+ V G +C C G AA G CE+ P ++ E P+G R
Sbjct: 1009 EDECIHPVPGKFRMDACCCAVG---AAWGTECEE--CPKPGTKEYETLCPRGAGFANRGD 1063
Query: 298 -LGFRPAEDDPHRCVDTDECQIAGVCQQ-MCVNYVGGFECYCSEGHELEADGISCS 351
L RP D + C G+C C N +G F+C C+ G L+ + +C+
Sbjct: 1064 VLTGRPFYKDINECK-----AFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCT 1114
Score = 37.0 bits (84), Expect = 0.068
Identities = 39/143 (27%), Positives = 53/143 (37%), Gaps = 16/143 (11%)
Query: 212 LCVKQPE----GGVGWSRAGPLCLGTGCSPDNGGCEH-ECVEEVDGHVSCRCTEGFRLAA 266
+C QP+ G + R G C G C+ C+ V G CRC G + +
Sbjct: 253 MCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTV-GSFECRCPAGHKQSE 311
Query: 267 DGRSCE--DPCAQAP--CEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVD--TDEC---Q 317
+ CE D C+ P CE Y C C G+ D RC+D T C
Sbjct: 312 TTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGY-VTSTDGSRCIDQRTGMCFSGL 370
Query: 318 IAGVCQQMCVNYVGGFECYCSEG 340
+ G C Q + +C C G
Sbjct: 371 VNGRCAQELPGRMTKMQCCCEPG 393
Score = 36.6 bits (83), Expect = 0.089
Identities = 24/76 (31%), Positives = 32/76 (42%), Gaps = 9/76 (11%)
Query: 275 CAQAPCEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIA-GVCQQM--CVNYVG 331
CA C Q + C C GF D C D DEC +CQ+ C+N G
Sbjct: 1819 CANGVCINQIG-----SFRCECPTGFS-YNDLLLVCEDIDECSNGDNLCQRNADCINSPG 1872
Query: 332 GFECYCSEGHELEADG 347
+ C C+ G +L +G
Sbjct: 1873 SYRCECAAGFKLSPNG 1888
Score = 30.8 bits (68), Expect = 4.9
Identities = 24/84 (28%), Positives = 32/84 (38%), Gaps = 9/84 (10%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCAQAPCEQQCEPGGPQ-- 290
C G C+ G C C +G+ L+ D R CE D C P C PG
Sbjct: 1654 CQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHP--GVCGPGTCYNT 1711
Query: 291 --GYSCHCRLGFRPAEDDPHRCVD 312
Y+C C + + H C+D
Sbjct: 1712 LGNYTCICPPEYMQV-NGGHNCMD 1734
>gi|56237021 fibrillin 3 precursor [Homo sapiens]
Length = 2809
Score = 76.3 bits (186), Expect = 1e-13
Identities = 44/123 (35%), Positives = 58/123 (47%), Gaps = 8/123 (6%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCAQAP--CEQQCEPGGPQ 290
C NGGC+ C+ +G C C +G+ L DGR+C D C + P C+Q P
Sbjct: 1159 CRVQNGGCDVHCIN-TEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPG 1217
Query: 291 GYSCHCRLGFRPAEDDPHRCVDTDECQI-AGVC-QQMCVNYVGGFECYCSEGHELEADGI 348
G+ C C GF A D CVD DEC + +C C N G F C+C G+ +
Sbjct: 1218 GHRCLCYDGFM-ATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGAT 1276
Query: 349 SCS 351
CS
Sbjct: 1277 GCS 1279
Score = 76.3 bits (186), Expect = 1e-13
Identities = 49/123 (39%), Positives = 59/123 (47%), Gaps = 16/123 (13%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPG----GPQ 290
CSP G C + V G C C +GF A DG CED A C+ G P
Sbjct: 1332 CSP-RGDCLN-----VPGSYRCTCRQGF--AGDGFFCEDRDECAENVDLCDNGQCLNAPG 1383
Query: 291 GYSCHCRLGFRPAEDDPHR-CVDTDECQIAGVCQ-QMCVNYVGGFECYCSEGHELEADGI 348
GY C C +GF P ED HR C D DEC +C C N G F C C+ G+EL+ G
Sbjct: 1384 GYRCECEMGFDPTED--HRACQDVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGG 1441
Query: 349 SCS 351
+C+
Sbjct: 1442 NCT 1444
Score = 69.7 bits (169), Expect = 9e-12
Identities = 38/122 (31%), Positives = 55/122 (45%), Gaps = 6/122 (4%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQG--- 291
C+ D C DG C+C G L A G +CED + + C G
Sbjct: 1075 CARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIG 1134
Query: 292 -YSCHCRLGFRPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGGFECYCSEGHELEADGIS 349
+ C C GF+ + D CVD +EC++ G C C+N G + C C +G+ L DG +
Sbjct: 1135 AFQCSCHAGFQ-STPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRA 1193
Query: 350 CS 351
C+
Sbjct: 1194 CA 1195
Score = 69.7 bits (169), Expect = 9e-12
Identities = 44/130 (33%), Positives = 57/130 (43%), Gaps = 8/130 (6%)
Query: 227 GPLCLGTG-CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQ 283
G C+G C C H + +G C C GF+ +AD C D C + PC
Sbjct: 1800 GGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNG 1859
Query: 284 CEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQ--IAGVCQ-QMCVNYVGGFECYCSEG 340
Y+C C GF + CVD DEC + VC+ C+N G F C C +G
Sbjct: 1860 TCKNIIGSYNCLCFPGFVVTHNGD--CVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDG 1917
Query: 341 HELEADGISC 350
EL ADG +C
Sbjct: 1918 FELTADGKNC 1927
Score = 67.4 bits (163), Expect = 5e-11
Identities = 41/120 (34%), Positives = 51/120 (42%), Gaps = 5/120 (4%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAP-CEQQCEPGGPQG 291
C G C +G C C GF L+ DG++C D CA + C
Sbjct: 493 CIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGS 552
Query: 292 YSCHCRLGFRPAEDDPHRCVDTDECQIAGVC-QQMCVNYVGGFECYCSEGHELEADGISC 350
+SC C+ GF A H C+D DECQ G+C C N G F C C G + DG C
Sbjct: 553 FSCLCKPGFLLAPGG-HYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVC 611
Score = 66.6 bits (161), Expect = 8e-11
Identities = 64/189 (33%), Positives = 70/189 (37%), Gaps = 52/189 (27%)
Query: 196 GSVAAVQCQAG---RGASLLCVKQPEGGVGWSRAGPLCLGTGCSPDNGGCEHECVEEVDG 252
GS +V C G RGAS LC K G G P+C GC NGG C+ G
Sbjct: 117 GSGCSVSCMNGGTCRGASCLCQK---GYTGTVCGQPIC-DRGCH--NGG---RCI----G 163
Query: 253 HVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQ---------------------G 291
C C GF G CE PC Q P G Q G
Sbjct: 164 PNRCACVYGFM----GPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWG 219
Query: 292 YSCH--------CRLGFRPAEDDPHRCVDTDECQ-IAGVCQQ-MCVNYVGGFECYCSEGH 341
C CR GF P C D DECQ + G+CQ CVN VG F C C GH
Sbjct: 220 LPCELCPAQPHPCRRGFIP-NIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGH 278
Query: 342 ELEADGISC 350
L +C
Sbjct: 279 RLSDSSAAC 287
Score = 66.6 bits (161), Expect = 8e-11
Identities = 71/247 (28%), Positives = 92/247 (37%), Gaps = 33/247 (13%)
Query: 124 GPCPAQRCVALEAS-----GEHRWLEGSCTLAVDGYL--CQFGFEGACPALQDEAGQAGP 176
G CP RCV S E L+ S L VD L C ++ +DE G P
Sbjct: 878 GVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWD------EDECGVTLP 931
Query: 177 AVYTTPFHLVSTEFEWLPFGSVAAVQCQAGRGA-SLLCVKQPEGGVGWSRAGPLCLG--- 232
Y S G+V V+C+A SL G+G++ L
Sbjct: 932 GKYRMDVCCCS-------IGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFY 984
Query: 233 ---TGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCAQAP--CEQQCE 285
C G C H G C C GF L A R+C D C +P C Q
Sbjct: 985 KDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTC 1044
Query: 286 PGGPQGYSCHCRLGFRPAEDDPHRCVDTDEC-QIAGVCQ-QMCVNYVGGFECYCSEGHEL 343
P + C C G+ C+D DEC + +C+ C N G ++C C GHEL
Sbjct: 1045 VNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHEL 1104
Query: 344 EADGISC 350
A G +C
Sbjct: 1105 TAKGTAC 1111
Score = 64.7 bits (156), Expect = 3e-10
Identities = 36/98 (36%), Positives = 46/98 (46%), Gaps = 4/98 (4%)
Query: 256 CRCTEGFRLAADGRSCE-DPCAQAPCEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTD 314
C C G+ G + D C +PC P Y C C GF+ A CVD D
Sbjct: 433 CECNVGYTQDVRGECIDVDECTSSPCHHGDCVNIPGTYHCRCYPGFQ-ATPTRQACVDVD 491
Query: 315 ECQIAG-VCQQ-MCVNYVGGFECYCSEGHELEADGISC 350
EC ++G +C CVN G F+C C+ G EL DG +C
Sbjct: 492 ECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNC 529
Score = 64.3 bits (155), Expect = 4e-10
Identities = 37/120 (30%), Positives = 48/120 (40%), Gaps = 5/120 (4%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPG----GPQ 290
C+ D C + E + G C C G+ A G+ C D A C+ G P
Sbjct: 686 CALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPG 745
Query: 291 GYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
YSC C GF +D C D DEC + +C N G + C C G L+ G C
Sbjct: 746 SYSCSCPPGFHFWQDT-EICKDVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFC 804
Score = 61.2 bits (147), Expect = 3e-09
Identities = 38/125 (30%), Positives = 48/125 (38%), Gaps = 16/125 (12%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--------PCAQAPCEQQCEP 286
C+ + G C + DG C C G+ L G +C D PC Q C
Sbjct: 2088 CAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIG- 2146
Query: 287 GGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGV-CQQMCVNYVGGFECYCSEGHELEA 345
G+ C C GF P C D DEC + + C C N G + C C G+ L
Sbjct: 2147 ----GFECACADGFEPGL--MMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLRE 2200
Query: 346 DGISC 350
DG C
Sbjct: 2201 DGAMC 2205
Score = 60.1 bits (144), Expect = 7e-09
Identities = 36/105 (34%), Positives = 46/105 (43%), Gaps = 9/105 (8%)
Query: 252 GHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQ----GYSCHCRLGFRPAEDDP 307
G C C +GF L ADG++C D C PG Q + C C GF+ D
Sbjct: 1908 GSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSD-- 1965
Query: 308 HRCVDTDEC-QIAGVCQ-QMCVNYVGGFECYCSEGHELEADGISC 350
C+D DEC + +C C N G F+C C G L +G C
Sbjct: 1966 -HCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRC 2009
Score = 59.7 bits (143), Expect = 1e-08
Identities = 36/121 (29%), Positives = 46/121 (38%), Gaps = 9/121 (7%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGG-----P 289
C+ C+ CV V G +CRC GF D C+ P C G P
Sbjct: 2450 CTSRQHNCQFLCVNTV-GAFTCRCPPGFTQHHQACFDNDECSAQP--GPCGAHGHCHNTP 2506
Query: 290 QGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGIS 349
+ C C GF H C D +EC CQ C N +GG+ C C +G +
Sbjct: 2507 GSFRCECHQGFTLVSSG-HGCEDVNECDGPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQ 2565
Query: 350 C 350
C
Sbjct: 2566 C 2566
Score = 58.5 bits (140), Expect = 2e-08
Identities = 36/116 (31%), Positives = 46/116 (39%), Gaps = 9/116 (7%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQ---- 290
CS + C C +G C C G+ L DG C D A +Q C G +
Sbjct: 2170 CSLNPLLCAFRC-HNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNL 2228
Query: 291 --GYSCHCRLGFRPAEDDPHRCVDTDECQI-AGVC-QQMCVNYVGGFECYCSEGHE 342
++C C G RP C D +EC +C CVN G F C C EG +
Sbjct: 2229 IGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQ 2284
Score = 58.2 bits (139), Expect = 3e-08
Identities = 40/133 (30%), Positives = 50/133 (37%), Gaps = 17/133 (12%)
Query: 219 GGVGWSRAGPLCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQA 278
GG GW LC G S C H +G C R CA
Sbjct: 2328 GGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDEC----------RMLAHLCAHG 2377
Query: 279 PCEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDEC-QIAGVCQQMCVNYVGGFECYC 337
C + CHC+ G+ P + C+D DEC Q+ C +C N G F C C
Sbjct: 2378 ECINSLG-----SFRCHCQAGYTP-DATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSC 2431
Query: 338 SEGHELEADGISC 350
G+ LE DG +C
Sbjct: 2432 PRGYLLEEDGRTC 2444
Score = 54.7 bits (130), Expect = 3e-07
Identities = 46/149 (30%), Positives = 62/149 (41%), Gaps = 14/149 (9%)
Query: 232 GTGCSPDNG-----GCEHECVEEVDGHVSCRCTEGFRLAADGRSC--EDPCAQAP--CEQ 282
G GC N C+H C ++ G+ C C +GF + C E+ CA +P C
Sbjct: 2523 GHGCEDVNECDGPHRCQHGCQNQLGGY-RCSCPQGFTQHSQWAQCVDENECALSPPTCGS 2581
Query: 283 QCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQ-IAGVCQQMCVNYVGGFECYCSEGH 341
G+ C C GF + C + DEC G C C N GGF C C +G+
Sbjct: 2582 ASCRNTLGGFRCVCPSGF-DFDQALGGCQEVDECAGRRGPCSYSCANTPGGFLCGCPQGY 2640
Query: 342 ELEADGISCSPAG-AMGAQASQDLGDELL 369
G S G + G Q + D +ELL
Sbjct: 2641 FRAGQGHCVSGLGFSPGPQDTPD-KEELL 2668
Score = 53.9 bits (128), Expect = 5e-07
Identities = 41/135 (30%), Positives = 52/135 (38%), Gaps = 23/135 (17%)
Query: 213 CVKQPEGGVGWSRAGPLCLGTGCSPDNGGCE--HECVEEVDGHVSCRCTEGFRLAADGRS 270
C K+P G GW LC G + C H V D D R
Sbjct: 2041 CSKRP--GEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPD---------------DSRE 2083
Query: 271 CEDPCAQAP--CEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQ-MCV 327
+ CA+ P C + C C G+ + CVDTDEC + C Q C
Sbjct: 2084 DVNECAENPGVCTNGVCVNTDGSFRCECPFGYS-LDFTGINCVDTDECSVGHPCGQGTCT 2142
Query: 328 NYVGGFECYCSEGHE 342
N +GGFEC C++G E
Sbjct: 2143 NVIGGFECACADGFE 2157
Score = 53.5 bits (127), Expect = 7e-07
Identities = 34/114 (29%), Positives = 47/114 (41%), Gaps = 6/114 (5%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPG---GPQG-YSCHCR 297
C H + G CRC GF+ ++C D C G +G + C C
Sbjct: 458 CHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCN 517
Query: 298 LGFRPAEDDPHRCVDTDECQIAGVC-QQMCVNYVGGFECYCSEGHELEADGISC 350
GF + D + CVD +EC + +C +C+N G F C C G L G C
Sbjct: 518 AGFELSPDGKN-CVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYC 570
Score = 52.8 bits (125), Expect = 1e-06
Identities = 33/119 (27%), Positives = 50/119 (42%), Gaps = 9/119 (7%)
Query: 235 CSPDNGGCEH--ECVEEVDGHVSCRCTEGFRLAADGRSC--EDPCAQAP--CEQQCEPGG 288
C C+ +C+ + G C+CT G++L+ G +C + C + P C
Sbjct: 1767 CGSRESPCQQNADCIN-IPGSYRCKCTRGYKLSPGG-ACVGRNECREIPNVCSHGDCMDT 1824
Query: 289 PQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADG 347
Y C C GF+ A D C+D DEC C N +G + C C G + +G
Sbjct: 1825 EGSYMCLCHRGFQ-ASADQTLCMDIDECDRQPCGNGTCKNIIGSYNCLCFPGFVVTHNG 1882
Score = 52.8 bits (125), Expect = 1e-06
Identities = 38/123 (30%), Positives = 47/123 (38%), Gaps = 12/123 (9%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED----PCAQAPCEQQCEPGGPQ 290
CS C C + G C C G+ L DGR+C+D Q C+ C
Sbjct: 2409 CSQVPKPCTFLC-KNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLC-VNTVG 2466
Query: 291 GYSCHCRLGFRPAEDDPHRCVDTDECQI-AGVC--QQMCVNYVGGFECYCSEGHELEADG 347
++C C GF C D DEC G C C N G F C C +G L + G
Sbjct: 2467 AFTCRCPPGF---TQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSG 2523
Query: 348 ISC 350
C
Sbjct: 2524 HGC 2526
Score = 51.2 bits (121), Expect = 3e-06
Identities = 33/112 (29%), Positives = 51/112 (45%), Gaps = 10/112 (8%)
Query: 246 CVEEVDGHVSCRCTEGFRLAADGRSCE--DPCA--QAPCEQQCE-PGGPQGYSCHCRLGF 300
C+ ++ G C C GF + +CE D C ++PC+Q + P Y C C G+
Sbjct: 1737 CINQI-GSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGY 1795
Query: 301 RPAEDDPHRCVDTDEC-QIAGVCQQ-MCVNYVGGFECYCSEGHELEADGISC 350
+ + CV +EC +I VC C++ G + C C G + AD C
Sbjct: 1796 KLSPGG--ACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLC 1845
Score = 48.5 bits (114), Expect = 2e-05
Identities = 43/162 (26%), Positives = 61/162 (37%), Gaps = 48/162 (29%)
Query: 232 GTGCSPDNGGCEHECVEEVD-----------GHVSCRCTEGFRLAADGRSCED----PC- 275
G GC+ DN EC + D G C C EGF+ + C D PC
Sbjct: 2247 GEGCTDDN-----ECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCF 2301
Query: 276 --------------AQAPCEQQCEPGGPQGYSCHCRLGFRPAEDD-----PH------RC 310
++A +C GG +G+ C L P PH
Sbjct: 2302 AEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEG 2361
Query: 311 VDTDECQ-IAGVCQQ-MCVNYVGGFECYCSEGHELEADGISC 350
D DEC+ +A +C C+N +G F C+C G+ +A +C
Sbjct: 2362 RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTC 2403
Score = 47.4 bits (111), Expect = 5e-05
Identities = 53/186 (28%), Positives = 63/186 (33%), Gaps = 53/186 (28%)
Query: 210 SLLCVKQPEGGVGWSRAGPLCLGTGCSP------DNGGCEH--ECVEE---------VDG 252
SLLC GW + P C P D C+ EC+ + G
Sbjct: 732 SLLCDN------GWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCVSGVCRNLAG 785
Query: 253 HVSCRCTEGFRLAADGRSCEDP----CAQAPCEQQCEP---------------GGPQGYS 293
+C+C G RL G C D C E +CE G G
Sbjct: 786 SYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGSP 845
Query: 294 CH-------CRLGFRPAEDDPHRCVDTDECQ-IAGVCQQ-MCVNYVGGFECYCSEGHELE 344
C C GF A C D +EC+ GVC CVN G F C C EG L+
Sbjct: 846 CERCEIDPACARGF--ARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLD 903
Query: 345 ADGISC 350
A G C
Sbjct: 904 ASGRLC 909
Score = 45.1 bits (105), Expect = 2e-04
Identities = 35/128 (27%), Positives = 44/128 (34%), Gaps = 35/128 (27%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGG------------P 289
C H E G C C G+ + C D +CE GG P
Sbjct: 1249 CLHGDCENTKGSFVCHCQLGYMVRKGATGCSD-------VDECEVGGHNCDSHASCLNIP 1301
Query: 290 QGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQM-------CVNYVGGFECYCSEGHE 342
+SC C G+ D C D DEC V Q+ C+N G + C C +G
Sbjct: 1302 GSFSCRCLPGW---VGDGFECHDLDEC----VSQEHRCSPRGDCLNVPGSYRCTCRQG-- 1352
Query: 343 LEADGISC 350
DG C
Sbjct: 1353 FAGDGFFC 1360
Score = 44.7 bits (104), Expect = 3e-04
Identities = 40/154 (25%), Positives = 53/154 (34%), Gaps = 40/154 (25%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDP-------------------- 274
CS + C G C C GF L+ +G C D
Sbjct: 1973 CSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAF 2032
Query: 275 --------CAQAPCE------QQCEPGGPQGYSCHCRLGFR--PAEDDPHRCVDTDEC-Q 317
C++ P E + C G + C G P DD D +EC +
Sbjct: 2033 NTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSRE--DVNECAE 2090
Query: 318 IAGVCQQ-MCVNYVGGFECYCSEGHELEADGISC 350
GVC +CVN G F C C G+ L+ GI+C
Sbjct: 2091 NPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINC 2124
Score = 44.3 bits (103), Expect = 4e-04
Identities = 71/274 (25%), Positives = 91/274 (33%), Gaps = 60/274 (21%)
Query: 138 GEHRWLEGSCTLAVDGYLCQFGFEGACPALQDE-AGQAGPAVYTTP---FHLVSTEFE-W 192
G H W + VD L G C L + GP P F L ST+ W
Sbjct: 754 GFHFWQDTEICKDVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCW 813
Query: 193 LPF----------GSVAAVQCQAGRGASL-----LCVKQPEGGVGWSR-AGPLCLGTG-C 235
L G+ +C A GA+ C P G++R G C C
Sbjct: 814 LKIQESRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNEC 873
Query: 236 SPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED----PCAQAPCEQQCE---PGG 288
G C + G C C EG L A GR C D PC E +C PG
Sbjct: 874 ESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGK 933
Query: 289 PQGYSCHCRLGF-----RPAEDDPHRC------------------------VDTDECQI- 318
+ C C +G A DP D +EC++
Sbjct: 934 YRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVF 993
Query: 319 AGVCQQ-MCVNYVGGFECYCSEGHELEADGISCS 351
G+C C N VG F C C+ G L+A +C+
Sbjct: 994 PGLCTHGTCRNTVGSFHCACAGGFALDAQERNCT 1027
Score = 43.1 bits (100), Expect = 0.001
Identities = 43/166 (25%), Positives = 52/166 (31%), Gaps = 42/166 (25%)
Query: 219 GGVGWSRAGPLCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQA 278
GG R G C D C + G C C + F L G C D A
Sbjct: 1432 GGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVDTRA-G 1490
Query: 279 PCEQQCEPGGPQGYSCHCRLGF----------------RPAE------------------ 304
C + G G SC +G P E
Sbjct: 1491 NCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPGGE 1550
Query: 305 -DDPHRCV----DTDECQ-IAGVCQQM-CVNYVGGFECYCSEGHEL 343
P+R D DECQ + G+CQ CVN G F+C C G+ L
Sbjct: 1551 GFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHL 1596
Score = 42.4 bits (98), Expect = 0.002
Identities = 19/62 (30%), Positives = 27/62 (43%), Gaps = 2/62 (3%)
Query: 289 PQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGI 348
P Y C C +G+ +D C+D DEC + CVN G + C C G +
Sbjct: 428 PSSYRCECNVGY--TQDVRGECIDVDECTSSPCHHGDCVNIPGTYHCRCYPGFQATPTRQ 485
Query: 349 SC 350
+C
Sbjct: 486 AC 487
Score = 42.4 bits (98), Expect = 0.002
Identities = 40/146 (27%), Positives = 55/146 (37%), Gaps = 10/146 (6%)
Query: 227 GPLCLGTG-CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAP--CEQQ 283
G C+ T C G C + ++G C C GF++ +D D C++ P C
Sbjct: 1924 GKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDHCIDIDECSEEPNLCLFG 1983
Query: 284 CEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQI-----AGVCQQMCVNYVGGFECYCS 338
P + C C GF D+ HRC DT + AG C C CS
Sbjct: 1984 TCTNSPGSFQCLCPPGF-VLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCS 2042
Query: 339 EGHELEADGISCSPAGAMGAQASQDL 364
+ E G C G+ A Q+L
Sbjct: 2043 K-RPGEGWGDPCELCPQEGSAAFQEL 2067
Score = 41.6 bits (96), Expect = 0.003
Identities = 41/176 (23%), Positives = 61/176 (34%), Gaps = 38/176 (21%)
Query: 210 SLLCVKQPEGGVGWSRAGPLCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGR 269
S C+ +P G + G C+ G C + +G C+C G + DGR
Sbjct: 552 SFSCLCKP--GFLLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGR 609
Query: 270 SCEDPCAQAPCEQQCEPGG-------------------PQGYSCHCRLGFRPAEDDPHRC 310
C D ++ C E G G+ C+L PA+D
Sbjct: 610 VCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQL--CPAKDSAEFQ 667
Query: 311 V-------------DTDECQI-AGVCQQ-MCVNYVGGFECYCSEGHELEADGISCS 351
D +EC + VC +C N G + C C+ G+E A G C+
Sbjct: 668 ALCSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCT 723
Score = 39.3 bits (90), Expect = 0.014
Identities = 33/127 (25%), Positives = 51/127 (40%), Gaps = 16/127 (12%)
Query: 239 NGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGYSCHCRL 298
NG C++E V + C C+ G++ PC P P P Y C
Sbjct: 1658 NGTCQNELAFNVTRKMCC-CSYNI-----GQAWNRPCEACPT-----PISPD-YQILCGN 1705
Query: 299 GFRPAEDDPH--RCVDTDEC-QIAGVCQQ-MCVNYVGGFECYCSEGHELEADGISCSPAG 354
D H + +D DEC +I +C +C+N +G F C C G + ++C
Sbjct: 1706 QAPGFLTDIHTGKPLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVD 1765
Query: 355 AMGAQAS 361
G++ S
Sbjct: 1766 ECGSRES 1772
Score = 37.0 bits (84), Expect = 0.068
Identities = 24/76 (31%), Positives = 30/76 (39%), Gaps = 9/76 (11%)
Query: 275 CAQAPCEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDEC-QIAGVCQQM--CVNYVG 331
CA C Q + C C GF C D DEC CQQ C+N G
Sbjct: 1732 CANGICINQIG-----SFRCECPAGFN-YNSILLACEDVDECGSRESPCQQNADCINIPG 1785
Query: 332 GFECYCSEGHELEADG 347
+ C C+ G++L G
Sbjct: 1786 SYRCKCTRGYKLSPGG 1801
>gi|169211436 PREDICTED: hypothetical protein [Homo sapiens]
Length = 280
Score = 75.1 bits (183), Expect = 2e-13
Identities = 57/229 (24%), Positives = 105/229 (45%), Gaps = 12/229 (5%)
Query: 450 PVVVSATHPTLPSAHQPPVIPATHPALSRDHQIPVIAANYPDLPSAYQPGILSVSHSAQP 509
P + ++ PTL ++ P + P + P L+ + +N P L + P + S
Sbjct: 52 PTLTPSSPPTLTPSNTPTLTPCSTPTLTPCSTPTLTPSNTPTLTPSSTPTLTPSSTPTLT 111
Query: 510 PAHQPPMISTKYPELFPAHQSPMFPDTRVAGTQTTTHLPGIPPNHAPLVTTLGAQLPPQA 569
P+ P + + P L P+ + P + T+++T P + P+ P +T + P
Sbjct: 112 PSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTRSST--PTLTPSSTPTLTP--SSTPTLT 167
Query: 570 PDALVLRTQATQLPIIPTAQPSLTTTSRSPVSPAHQISV-PAAT---QPAALPTLLPSQS 625
P + T ++ + P+++P LT +S ++P+ ++ P++T P+ PTL+PS +
Sbjct: 168 PSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSNTPTLIPSST 227
Query: 626 PTNQTSPISPTHPHSKAPQIPREDGPS---PKLALWLPSPAPTAAPTAL 671
PT T +PT S P + R P+ PS PT P++L
Sbjct: 228 PT-LTPSSTPTLTPSSRPTLTRSSTPTLTPSSTPTLTPSSTPTLTPSSL 275
Score = 68.6 bits (166), Expect = 2e-11
Identities = 55/236 (23%), Positives = 103/236 (43%), Gaps = 26/236 (11%)
Query: 398 MEPTQPPDFALAYRPSFPEDREPQIPYPEPTWPPPLSAPRVPYHSSVLSVTR-PVVVSAT 456
+ P+ PP + P+ P PT P + P ++ L+ + P + ++
Sbjct: 54 LTPSSPPTLTPSNTPTLT-------PCSTPTLTPCSTPTLTPSNTPTLTPSSTPTLTPSS 106
Query: 457 HPTLPSAHQPPVIPATHPALSRDHQIPVIAANYPDLPSAYQPGILSVSHSAQPPAHQPPM 516
PTL + P + P++ P L+ + ++ P L + P + S P+ P +
Sbjct: 107 TPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTRSSTPTLTPSSTPTLTPSSTPTL 166
Query: 517 ISTKYPELFPAHQSPMFPDTRVAGTQTTTHLPGIPPNHAPLVTTLGAQLPPQAPDALVLR 576
+ P L P+ + P +R T+++T P + P+ P +T P +
Sbjct: 167 TPSSTPTLTPSSTPTLTPSSRPILTRSST--PTLTPSSTPTLT----------PSSTPTL 214
Query: 577 TQATQLPIIPTAQPSLTTTSRSPVSPAH-----QISVPAATQPAALPTLLPSQSPT 627
T + +IP++ P+LT +S ++P+ + S P T P++ PTL PS +PT
Sbjct: 215 TPSNTPTLIPSSTPTLTPSSTPTLTPSSRPTLTRSSTPTLT-PSSTPTLTPSSTPT 269
Score = 50.1 bits (118), Expect = 8e-06
Identities = 40/179 (22%), Positives = 78/179 (43%), Gaps = 8/179 (4%)
Query: 398 MEPTQPPDFALAYRPSFPEDREPQI-PYPEPTWPPPLSAPRVPYHSS--VLSVTRPVVVS 454
+ P+ P + P+ P + P PT P S P + S+ + + P +
Sbjct: 102 LTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPS-STPTLTRSSTPTLTPSSTPTLTP 160
Query: 455 ATHPTLPSAHQPPVIPATHPALSRDHQIPVIAANYPDLPSAYQPGILSVSHSAQPPAHQP 514
++ PTL + P + P++ P L+ + + ++ P L + P + S P++ P
Sbjct: 161 SSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSNTP 220
Query: 515 PMISTKYPELFPAHQSPMFPDTRVAGTQTTTHLPGIPPNHAPLVTTLGAQLPPQAPDAL 573
+I + P L P+ + P +R T+++T P + P+ P +T + P P +L
Sbjct: 221 TLIPSSTPTLTPSSTPTLTPSSRPTLTRSST--PTLTPSSTPTLTP--SSTPTLTPSSL 275
>gi|86788132 EGF-containing fibulin-like extracellular matrix
protein 1 precursor [Homo sapiens]
Length = 493
Score = 74.3 bits (181), Expect = 4e-13
Identities = 58/223 (26%), Positives = 96/223 (43%), Gaps = 34/223 (15%)
Query: 137 SGEHRWLEGSCTLAVDGYLCQFGFEGACPALQDEAGQAGPAVYTTPFHLV----STEFEW 192
SG + + ++A G L GF + A+ AGP + T + V + +
Sbjct: 95 SGATTGVVAASSMATSGVLPGGGFVASAAAV------AGPEMQTGRNNFVIRRNPADPQR 148
Query: 193 LPFGSVAAVQCQAGRGASL--LC--VKQPEGGVGWSRAGPLCLGTGCSPDNGGCEHECVE 248
+P +QC AG S +C + + G RA +C+
Sbjct: 149 IPSNPSHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCIN---------------- 192
Query: 249 EVDGHVSCRCTEGFRLAADGRSCEDPCAQAP-CEQQCEPGGPQGYSCHCRLGFRPAEDDP 307
+ G +C+C G++ + D C P C Q+C P + C C GF+ A ++
Sbjct: 193 -LRGSFACQCPPGYQKRGEQCVDIDECTIPPYCHQRCV-NTPGSFYCQCSPGFQLAANN- 249
Query: 308 HRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
+ CVD +EC + C Q C N +G F C C++G+EL +D ++C
Sbjct: 250 YTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNC 292
Score = 67.4 bits (163), Expect = 5e-11
Identities = 53/187 (28%), Positives = 82/187 (43%), Gaps = 26/187 (13%)
Query: 222 GWSRAGPLCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PC-AQA 278
G+ + G C+ C CV G C+C+ GF+LAA+ +C D C A
Sbjct: 204 GYQKRGEQCVDIDECTIPPYCHQRCVN-TPGSFYCQCSPGFQLAANNYTCVDINECDASN 262
Query: 279 PCEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAG-VCQQMCVNYVGGFECYC 337
C QQC + C C G+ + D + C D DEC+ + +CQ CVN G F C C
Sbjct: 263 QCAQQCY-NILGSFICQCNQGYELSSDRLN-CEDIDECRTSSYLCQYQCVNEPGKFSCMC 320
Query: 338 SEGHELEADGISCSPAGAMGAQASQDLGDELLDDGEDEEDEDEAWKAFNGGWTEMPGILW 397
+G+++ + ++ QD+ + + +E EDE ++GG+ P
Sbjct: 321 PQGYQV------------VRSRTCQDINE---CETTNECREDEMCWNYHGGFRCYP---- 361
Query: 398 MEPTQPP 404
P Q P
Sbjct: 362 RNPCQDP 368
>gi|86788015 EGF-containing fibulin-like extracellular matrix
protein 1 precursor [Homo sapiens]
Length = 493
Score = 74.3 bits (181), Expect = 4e-13
Identities = 58/223 (26%), Positives = 96/223 (43%), Gaps = 34/223 (15%)
Query: 137 SGEHRWLEGSCTLAVDGYLCQFGFEGACPALQDEAGQAGPAVYTTPFHLV----STEFEW 192
SG + + ++A G L GF + A+ AGP + T + V + +
Sbjct: 95 SGATTGVVAASSMATSGVLPGGGFVASAAAV------AGPEMQTGRNNFVIRRNPADPQR 148
Query: 193 LPFGSVAAVQCQAGRGASL--LC--VKQPEGGVGWSRAGPLCLGTGCSPDNGGCEHECVE 248
+P +QC AG S +C + + G RA +C+
Sbjct: 149 IPSNPSHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCIN---------------- 192
Query: 249 EVDGHVSCRCTEGFRLAADGRSCEDPCAQAP-CEQQCEPGGPQGYSCHCRLGFRPAEDDP 307
+ G +C+C G++ + D C P C Q+C P + C C GF+ A ++
Sbjct: 193 -LRGSFACQCPPGYQKRGEQCVDIDECTIPPYCHQRCV-NTPGSFYCQCSPGFQLAANN- 249
Query: 308 HRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
+ CVD +EC + C Q C N +G F C C++G+EL +D ++C
Sbjct: 250 YTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNC 292
Score = 67.4 bits (163), Expect = 5e-11
Identities = 53/187 (28%), Positives = 82/187 (43%), Gaps = 26/187 (13%)
Query: 222 GWSRAGPLCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PC-AQA 278
G+ + G C+ C CV G C+C+ GF+LAA+ +C D C A
Sbjct: 204 GYQKRGEQCVDIDECTIPPYCHQRCVN-TPGSFYCQCSPGFQLAANNYTCVDINECDASN 262
Query: 279 PCEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAG-VCQQMCVNYVGGFECYC 337
C QQC + C C G+ + D + C D DEC+ + +CQ CVN G F C C
Sbjct: 263 QCAQQCY-NILGSFICQCNQGYELSSDRLN-CEDIDECRTSSYLCQYQCVNEPGKFSCMC 320
Query: 338 SEGHELEADGISCSPAGAMGAQASQDLGDELLDDGEDEEDEDEAWKAFNGGWTEMPGILW 397
+G+++ + ++ QD+ + + +E EDE ++GG+ P
Sbjct: 321 PQGYQV------------VRSRTCQDINE---CETTNECREDEMCWNYHGGFRCYP---- 361
Query: 398 MEPTQPP 404
P Q P
Sbjct: 362 RNPCQDP 368
>gi|9665262 EGF-containing fibulin-like extracellular matrix protein
1 precursor [Homo sapiens]
Length = 493
Score = 74.3 bits (181), Expect = 4e-13
Identities = 58/223 (26%), Positives = 96/223 (43%), Gaps = 34/223 (15%)
Query: 137 SGEHRWLEGSCTLAVDGYLCQFGFEGACPALQDEAGQAGPAVYTTPFHLV----STEFEW 192
SG + + ++A G L GF + A+ AGP + T + V + +
Sbjct: 95 SGATTGVVAASSMATSGVLPGGGFVASAAAV------AGPEMQTGRNNFVIRRNPADPQR 148
Query: 193 LPFGSVAAVQCQAGRGASL--LC--VKQPEGGVGWSRAGPLCLGTGCSPDNGGCEHECVE 248
+P +QC AG S +C + + G RA +C+
Sbjct: 149 IPSNPSHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCIN---------------- 192
Query: 249 EVDGHVSCRCTEGFRLAADGRSCEDPCAQAP-CEQQCEPGGPQGYSCHCRLGFRPAEDDP 307
+ G +C+C G++ + D C P C Q+C P + C C GF+ A ++
Sbjct: 193 -LRGSFACQCPPGYQKRGEQCVDIDECTIPPYCHQRCV-NTPGSFYCQCSPGFQLAANN- 249
Query: 308 HRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
+ CVD +EC + C Q C N +G F C C++G+EL +D ++C
Sbjct: 250 YTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNC 292
Score = 67.4 bits (163), Expect = 5e-11
Identities = 53/187 (28%), Positives = 82/187 (43%), Gaps = 26/187 (13%)
Query: 222 GWSRAGPLCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PC-AQA 278
G+ + G C+ C CV G C+C+ GF+LAA+ +C D C A
Sbjct: 204 GYQKRGEQCVDIDECTIPPYCHQRCVN-TPGSFYCQCSPGFQLAANNYTCVDINECDASN 262
Query: 279 PCEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAG-VCQQMCVNYVGGFECYC 337
C QQC + C C G+ + D + C D DEC+ + +CQ CVN G F C C
Sbjct: 263 QCAQQCY-NILGSFICQCNQGYELSSDRLN-CEDIDECRTSSYLCQYQCVNEPGKFSCMC 320
Query: 338 SEGHELEADGISCSPAGAMGAQASQDLGDELLDDGEDEEDEDEAWKAFNGGWTEMPGILW 397
+G+++ + ++ QD+ + + +E EDE ++GG+ P
Sbjct: 321 PQGYQV------------VRSRTCQDINE---CETTNECREDEMCWNYHGGFRCYP---- 361
Query: 398 MEPTQPP 404
P Q P
Sbjct: 362 RNPCQDP 368
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.445
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,210,992
Number of Sequences: 37866
Number of extensions: 2458692
Number of successful extensions: 19108
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 210
Number of HSP's successfully gapped in prelim test: 1002
Number of HSP's that attempted gapping in prelim test: 11626
Number of HSP's gapped (non-prelim): 5051
length of query: 757
length of database: 18,247,518
effective HSP length: 110
effective length of query: 647
effective length of database: 14,082,258
effective search space: 9111220926
effective search space used: 9111220926
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.