BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|9910526 opsin 1 (cone pigments), long-wave-sensitive [Homo sapiens] (364 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|9910526 opsin 1 (cone pigments), long-wave-sensitive [Homo sa... 752 0.0 gi|114687592 opsin 1 (cone pigments), medium-wave-sensitive 2 [H... 729 0.0 gi|4503965 opsin 1 (cone pigments), medium-wave-sensitive [Homo ... 729 0.0 gi|4502387 opsin 1 (cone pigments), short-wave-sensitive [Homo s... 298 7e-81 gi|4506527 rhodopsin [Homo sapiens] 289 2e-78 gi|71999131 opsin 3 [Homo sapiens] 146 3e-35 gi|5730019 peropsin [Homo sapiens] 142 5e-34 gi|15150803 opsin 4 isoform 1 [Homo sapiens] 139 3e-33 gi|71999143 opsin 4 isoform 2 [Homo sapiens] 137 1e-32 gi|38678524 opsin 5 isoform 1 [Homo sapiens] 122 5e-28 gi|5174593 melatonin receptor 1A [Homo sapiens] 96 5e-20 gi|157426873 tachykinin receptor 2 [Homo sapiens] 93 4e-19 gi|39725940 opioid receptor, kappa 1 [Homo sapiens] 87 2e-17 gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens] 87 2e-17 gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens] 87 2e-17 gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens] 87 2e-17 gi|4507343 tachykinin receptor 1 isoform long [Homo sapiens] 86 4e-17 gi|7669548 tachykinin receptor 3 [Homo sapiens] 86 7e-17 gi|150170722 G protein-coupled receptor 50 [Homo sapiens] 85 1e-16 gi|21264324 trace amine associated receptor 1 [Homo sapiens] 84 2e-16 gi|7669546 tachykinin receptor 1 isoform short [Homo sapiens] 82 6e-16 gi|5174595 melatonin receptor 1B [Homo sapiens] 82 8e-16 gi|223633971 G protein-coupled receptor 83 [Homo sapiens] 81 1e-15 gi|4557859 somatostatin receptor 2 [Homo sapiens] 80 3e-15 gi|223633986 trace amine associated receptor 5 [Homo sapiens] 80 3e-15 gi|4557865 somatostatin receptor 5 [Homo sapiens] 79 6e-15 gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens] 79 6e-15 gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens] 79 6e-15 gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens] 79 6e-15 gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens] 79 6e-15 >gi|9910526 opsin 1 (cone pigments), long-wave-sensitive [Homo sapiens] Length = 364 Score = 752 bits (1941), Expect = 0.0 Identities = 364/364 (100%), Positives = 364/364 (100%) Query: 1 MAQQWSLQRLAGRHPQDSYEDSTQSSIFTYTNSNSTRGPFEGPNYHIAPRWVYHLTSVWM 60 MAQQWSLQRLAGRHPQDSYEDSTQSSIFTYTNSNSTRGPFEGPNYHIAPRWVYHLTSVWM Sbjct: 1 MAQQWSLQRLAGRHPQDSYEDSTQSSIFTYTNSNSTRGPFEGPNYHIAPRWVYHLTSVWM 60 Query: 61 IFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISIVNQVSGYFV 120 IFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISIVNQVSGYFV Sbjct: 61 IFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISIVNQVSGYFV 120 Query: 121 LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNVRFDAKLAIVGIAFSWIWS 180 LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNVRFDAKLAIVGIAFSWIWS Sbjct: 121 LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNVRFDAKLAIVGIAFSWIWS 180 Query: 181 AVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIMLCYL 240 AVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIMLCYL Sbjct: 181 AVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIMLCYL 240 Query: 241 QVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAANPGYAFH 300 QVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAANPGYAFH Sbjct: 241 QVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAANPGYAFH 300 Query: 301 PLMAALPAYFAKSATIYNPVIYVFMNRQFRNCILQLFGKKVDDGSELSSASKTEVSSVSS 360 PLMAALPAYFAKSATIYNPVIYVFMNRQFRNCILQLFGKKVDDGSELSSASKTEVSSVSS Sbjct: 301 PLMAALPAYFAKSATIYNPVIYVFMNRQFRNCILQLFGKKVDDGSELSSASKTEVSSVSS 360 Query: 361 VSPA 364 VSPA Sbjct: 361 VSPA 364 >gi|114687592 opsin 1 (cone pigments), medium-wave-sensitive 2 [Homo sapiens] Length = 364 Score = 729 bits (1881), Expect = 0.0 Identities = 349/364 (95%), Positives = 357/364 (98%) Query: 1 MAQQWSLQRLAGRHPQDSYEDSTQSSIFTYTNSNSTRGPFEGPNYHIAPRWVYHLTSVWM 60 MAQQWSLQRLAGRHPQDSYEDSTQSSIFTYTNSNSTRGPFEGPNYHIAPRWVYHLTSVWM Sbjct: 1 MAQQWSLQRLAGRHPQDSYEDSTQSSIFTYTNSNSTRGPFEGPNYHIAPRWVYHLTSVWM 60 Query: 61 IFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISIVNQVSGYFV 120 IFVV ASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTIS+VNQV GYFV Sbjct: 61 IFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISVVNQVYGYFV 120 Query: 121 LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNVRFDAKLAIVGIAFSWIWS 180 LGHPMCVLEGYTVSLCGITGLWSLAIISWERW+VVCKPFGNVRFDAKLAIVGIAFSWIW+ Sbjct: 121 LGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNVRFDAKLAIVGIAFSWIWA 180 Query: 181 AVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIMLCYL 240 AVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCI PL+II+LCYL Sbjct: 181 AVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSIIVLCYL 240 Query: 241 QVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAANPGYAFH 300 QVWLAIRAVAKQQKESESTQKAEKEVTRMVVVM+ A+C CWGPY FFACFAAANPGY FH Sbjct: 241 QVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMVLAFCFCWGPYAFFACFAAANPGYPFH 300 Query: 301 PLMAALPAYFAKSATIYNPVIYVFMNRQFRNCILQLFGKKVDDGSELSSASKTEVSSVSS 360 PLMAALPA+FAKSATIYNPVIYVFMNRQFRNCILQLFGKKVDDGSELSSASKTEVSSVSS Sbjct: 301 PLMAALPAFFAKSATIYNPVIYVFMNRQFRNCILQLFGKKVDDGSELSSASKTEVSSVSS 360 Query: 361 VSPA 364 VSPA Sbjct: 361 VSPA 364 >gi|4503965 opsin 1 (cone pigments), medium-wave-sensitive [Homo sapiens] Length = 364 Score = 729 bits (1881), Expect = 0.0 Identities = 349/364 (95%), Positives = 357/364 (98%) Query: 1 MAQQWSLQRLAGRHPQDSYEDSTQSSIFTYTNSNSTRGPFEGPNYHIAPRWVYHLTSVWM 60 MAQQWSLQRLAGRHPQDSYEDSTQSSIFTYTNSNSTRGPFEGPNYHIAPRWVYHLTSVWM Sbjct: 1 MAQQWSLQRLAGRHPQDSYEDSTQSSIFTYTNSNSTRGPFEGPNYHIAPRWVYHLTSVWM 60 Query: 61 IFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISIVNQVSGYFV 120 IFVV ASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTIS+VNQV GYFV Sbjct: 61 IFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISVVNQVYGYFV 120 Query: 121 LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNVRFDAKLAIVGIAFSWIWS 180 LGHPMCVLEGYTVSLCGITGLWSLAIISWERW+VVCKPFGNVRFDAKLAIVGIAFSWIW+ Sbjct: 121 LGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNVRFDAKLAIVGIAFSWIWA 180 Query: 181 AVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIMLCYL 240 AVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCI PL+II+LCYL Sbjct: 181 AVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSIIVLCYL 240 Query: 241 QVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAANPGYAFH 300 QVWLAIRAVAKQQKESESTQKAEKEVTRMVVVM+ A+C CWGPY FFACFAAANPGY FH Sbjct: 241 QVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMVLAFCFCWGPYAFFACFAAANPGYPFH 300 Query: 301 PLMAALPAYFAKSATIYNPVIYVFMNRQFRNCILQLFGKKVDDGSELSSASKTEVSSVSS 360 PLMAALPA+FAKSATIYNPVIYVFMNRQFRNCILQLFGKKVDDGSELSSASKTEVSSVSS Sbjct: 301 PLMAALPAFFAKSATIYNPVIYVFMNRQFRNCILQLFGKKVDDGSELSSASKTEVSSVSS 360 Query: 361 VSPA 364 VSPA Sbjct: 361 VSPA 364 >gi|4502387 opsin 1 (cone pigments), short-wave-sensitive [Homo sapiens] Length = 348 Score = 298 bits (762), Expect = 7e-81 Identities = 145/339 (42%), Positives = 220/339 (64%), Gaps = 2/339 (0%) Query: 23 TQSSIFTYTNSNSTRGPFEGPNYHIAPRWVYHLTSVWMIFVVTASVFTNGLVLAATMKFK 82 ++ + + N +S GP++GP YHIAP W ++L + +M V N +VL AT+++K Sbjct: 5 SEEEFYLFKNISSV-GPWDGPQYHIAPVWAFYLQAAFMGTVFLIGFPLNAMVLVATLRYK 63 Query: 83 KLRHPLNWILVNLAVADLAETVIASTISIVNQVSGYFVLGHPMCVLEGYTVSLCGITGLW 142 KLR PLN+ILVN++ + + V +GYFV G +C LEG+ ++ G+ W Sbjct: 64 KLRQPLNYILVNVSFGGFLLCIFSVFPVFVASCNGYFVFGRHVCALEGFLGTVAGLVTGW 123 Query: 143 SLAIISWERWLVVCKPFGNVRFDAKLAIVGIAFSWIWSAVWTAPPIFGWSRYWPHGLKTS 202 SLA +++ER++V+CKPFGN RF +K A+ + +W + PP FGWSR+ P GL+ S Sbjct: 124 SLAFLAFERYIVICKPFGNFRFSSKHALTVVLATWTIGIGVSIPPFFGWSRFIPEGLQCS 183 Query: 203 CGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIMLCYLQVWLAIRAVAKQQKESESTQKA 262 CGPD ++ + +SY L + C I+PL++I Y Q+ A++AVA QQ+ES +TQKA Sbjct: 184 CGPDWYTVGTKYRSESYTWFLFIFCFIVPLSLICFSYTQLLRALKAVAAQQQESATTQKA 243 Query: 263 EKEVTRMVVVMIFAYCVCWGPYTFFACFAAANPGYAFHPLMAALPAYFAKSATIYNPVIY 322 E+EV+RMVVVM+ ++CVC+ PY FA + N + + +P++F+KSA IYNP+IY Sbjct: 244 EREVSRMVVVMVGSFCVCYVPYAAFAMYMVNNRNHGLDLRLVTIPSFFSKSACIYNPIIY 303 Query: 323 VFMNRQFRNCILQLF-GKKVDDGSELSSASKTEVSSVSS 360 FMN+QF+ CI+++ GK + D S+ S+ KTEVS+VSS Sbjct: 304 CFMNKQFQACIMKMVCGKAMTDESDTCSSQKTEVSTVSS 342 >gi|4506527 rhodopsin [Homo sapiens] Length = 348 Score = 289 bits (740), Expect = 2e-78 Identities = 149/345 (43%), Positives = 211/345 (61%), Gaps = 6/345 (1%) Query: 21 DSTQSSIFTYTNSNST---RGPFEGPNYHIAPRWVYHLTSVWMIFVVTASVFTNGLVLAA 77 + T+ F SN+T R PFE P Y++A W + + + +M ++ N L L Sbjct: 2 NGTEGPNFYVPFSNATGVVRSPFEYPQYYLAEPWQFSMLAAYMFLLIVLGFPINFLTLYV 61 Query: 78 TMKFKKLRHPLNWILVNLAVADLAETVIASTISIVNQVSGYFVLGHPMCVLEGYTVSLCG 137 T++ KKLR PLN+IL+NLAVADL + T ++ + GYFV G C LEG+ +L G Sbjct: 62 TVQHKKLRTPLNYILLNLAVADLFMVLGGFTSTLYTSLHGYFVFGPTGCNLEGFFATLGG 121 Query: 138 ITGLWSLAIISWERWLVVCKPFGNVRFDAKLAIVGIAFSWIWSAVWTAPPIFGWSRYWPH 197 LWSL +++ ER++VVCKP N RF AI+G+AF+W+ + APP+ GWSRY P Sbjct: 122 EIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLAGWSRYIPE 181 Query: 198 GLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIMLCYLQVWLAIRAVAKQQKESE 257 GL+ SCG D ++ +S++I + V IP+ II CY Q+ ++ A QQ+ES Sbjct: 182 GLQCSCGIDYYTLKPEVNNESFVIYMFVVHFTIPMIIIFFCYGQLVFTVKEAAAQQQESA 241 Query: 258 STQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAANPGYAFHPLMAALPAYFAKSATIY 317 +TQKAEKEVTRMV++M+ A+ +CW PY A + + G F P+ +PA+FAKSA IY Sbjct: 242 TTQKAEKEVTRMVIIMVIAFLICWVPYASVAFYIFTHQGSNFGPIFMTIPAFFAKSAAIY 301 Query: 318 NPVIYVFMNRQFRNCILQLF--GKK-VDDGSELSSASKTEVSSVS 359 NPVIY+ MN+QFRNC+L GK + D ++ SKTE S V+ Sbjct: 302 NPVIYIMMNKQFRNCMLTTICCGKNPLGDDEASATVSKTETSQVA 346 >gi|71999131 opsin 3 [Homo sapiens] Length = 402 Score = 146 bits (368), Expect = 3e-35 Identities = 91/276 (32%), Positives = 146/276 (52%), Gaps = 15/276 (5%) Query: 68 VFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISIVNQVSGYFVLGHPMCV 127 V N LVL KF++LR P + +LVN++++DL ++ T + V+ + +V CV Sbjct: 56 VGNNLLVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFVSCLRNGWVWDTVGCV 115 Query: 128 LEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNVR-FDAKLAIVGIAFSWIWSAVWTAP 186 +G++ SL GI + +L ++++ER++ V + R + A I + W++S W Sbjct: 116 WDGFSGSLFGIVSIATLTVLAYERYIRVV----HARVINFSWAWRAITYIWLYSLAWAGA 171 Query: 187 PIFGWSRYW--PHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIMLCYLQVWL 244 P+ GW+RY HGL G V S S+++ L + C ++PL +I CY + Sbjct: 172 PLLGWNRYILDVHGL----GCTVDWKSKDANDSSFVLFLFLGCLVVPLGVIAHCYGHILY 227 Query: 245 AIRAVA----KQQKESESTQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAANPGYAFH 300 +IR + Q + K EK++ +M +MIF + VCW PY G+ Sbjct: 228 SIRMLRCVEDLQTIQVIKILKYEKKLAKMCFLMIFTFLVCWMPYIVICFLVVNGHGHLVT 287 Query: 301 PLMAALPAYFAKSATIYNPVIYVFMNRQFRNCILQL 336 P ++ + FAKS T+YNPVIYVFM R+FR +LQL Sbjct: 288 PTISIVSYLFAKSNTVYNPVIYVFMIRKFRRSLLQL 323 >gi|5730019 peropsin [Homo sapiens] Length = 337 Score = 142 bits (358), Expect = 5e-34 Identities = 87/310 (28%), Positives = 149/310 (48%), Gaps = 12/310 (3%) Query: 53 YHLTSVWMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISIV 112 +++ + ++I S+ +N +VL +K+K+LR P N I++NLAV D+ + I +S Sbjct: 25 HNIVATYLIMAGMISIISNIIVLGIFIKYKELRTPTNAIIINLAVTDIGVSSIGYPMSAA 84 Query: 113 NQVSGYFVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNVRFDAKLAIVG 172 + + G + G+ C + G+ + L +++ +R+L +C P R I Sbjct: 85 SDLYGSWKFGYAGCQVYAGLNIFFGMASIGLLTVVAVDRYLTICLPDVGRRMTTNTYIGL 144 Query: 173 IAFSWIWSAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPL 232 I +WI W PI GW+ Y P +C + + SY + ++ I+PL Sbjct: 145 ILGAWINGLFWALMPIIGWASYAPDPTGATC--TINWRKNDRSFVSYTMTVIAINFIVPL 202 Query: 233 AIIMLCYLQVWLAIRAVAKQQKESESTQKAEK------EVTRMVVVMIFAYCVCWGPYTF 286 ++ CY V L+I K S+ T+ + +VT+M V+MI + V W PY+ Sbjct: 203 TVMFYCYYHVTLSI----KHHTTSDCTESLNRDWSDQIDVTKMSVIMICMFLVAWSPYSI 258 Query: 287 FACFAAANPGYAFHPLMAALPAYFAKSATIYNPVIYVFMNRQFRNCILQLFGKKVDDGSE 346 +A+ P MA + FAKS+T YNP IYV N++FR +L +F + Sbjct: 259 VCLWASFGDPKKIPPPMAIIAPLFAKSSTFYNPCIYVVANKKFRRAMLAMFKCQTHQTMP 318 Query: 347 LSSASKTEVS 356 ++S +VS Sbjct: 319 VTSILPMDVS 328 >gi|15150803 opsin 4 isoform 1 [Homo sapiens] Length = 478 Score = 139 bits (351), Expect = 3e-33 Identities = 92/340 (27%), Positives = 164/340 (48%), Gaps = 25/340 (7%) Query: 18 SYEDSTQSSIFTYTNSNSTRGPFEG---------PNYHIAPRWVYHLTSVWMIFVVTASV 68 S+ DS+QSSI + S G P + Y L +V ++ +T + Sbjct: 27 SWWDSSQSSISSLGRLPSISPTAPGTWAAAWVPLPTVDVPDHAHYTLGTVILLVGLTG-M 85 Query: 69 FTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISIVNQVSGYFVLGHPMCVL 128 N V+ + + LR P N ++NLAV+D + + + + + ++ G C Sbjct: 86 LGNLTVIYTFCRSRSLRTPANMFIINLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEF 145 Query: 129 EGYTVSLCGITGLWSLAIISWERWLVVCKPFGNVRFDAKLAIVGIAFS-WIWSAVWTAPP 187 + +L GI+ + +L I+ +R+LV+ +P +K + W+++ W+ PP Sbjct: 146 YAFCGALFGISSMITLTAIALDRYLVITRPLATFGVASKRRAAFVLLGVWLYALAWSLPP 205 Query: 188 IFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIMLCYLQVWLAIR 247 FGWS Y P GL TSC D S + P V++Y ++L +PL II+ CY+ ++ AIR Sbjct: 206 FFGWSAYVPEGLLTSCSWDYMSFT--PAVRAYTMLLCCFVFFLPLLIIIYCYIFIFRAIR 263 Query: 248 ---------AVAKQQKES---ESTQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAANP 295 K ES ++E ++ ++++++I + + W PY+ A A A Sbjct: 264 ETGRALQTFGACKGNGESLWQRQRLQSECKMAKIMLLVILLFVLSWAPYSAVALVAFAGY 323 Query: 296 GYAFHPLMAALPAYFAKSATIYNPVIYVFMNRQFRNCILQ 335 + P M+++PA AK++ I+NP+IY + ++R I Q Sbjct: 324 AHVLTPYMSSVPAVIAKASAIHNPIIYAITHPKYRVAIAQ 363 >gi|71999143 opsin 4 isoform 2 [Homo sapiens] Length = 489 Score = 137 bits (346), Expect = 1e-32 Identities = 77/270 (28%), Positives = 139/270 (51%), Gaps = 15/270 (5%) Query: 79 MKFKKLRHPLNWILVNLAVADLAETVIASTISIVNQVSGYFVLGHPMCVLEGYTVSLCGI 138 M+ + LR P N ++NLAV+D + + + + + ++ G C + +L GI Sbjct: 107 MQSRSLRTPANMFIINLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGI 166 Query: 139 TGLWSLAIISWERWLVVCKPFGNVRFDAKLAIVGIAFS-WIWSAVWTAPPIFGWSRYWPH 197 + + +L I+ +R+LV+ +P +K + W+++ W+ PP FGWS Y P Sbjct: 167 SSMITLTAIALDRYLVITRPLATFGVASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPE 226 Query: 198 GLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIMLCYLQVWLAIR---------A 248 GL TSC D S + P V++Y ++L +PL II+ CY+ ++ AIR Sbjct: 227 GLLTSCSWDYMSFT--PAVRAYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFG 284 Query: 249 VAKQQKES---ESTQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAANPGYAFHPLMAA 305 K ES ++E ++ ++++++I + + W PY+ A A A + P M++ Sbjct: 285 ACKGNGESLWQRQRLQSECKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSS 344 Query: 306 LPAYFAKSATIYNPVIYVFMNRQFRNCILQ 335 +PA AK++ I+NP+IY + ++R I Q Sbjct: 345 VPAVIAKASAIHNPIIYAITHPKYRVAIAQ 374 >gi|38678524 opsin 5 isoform 1 [Homo sapiens] Length = 354 Score = 122 bits (306), Expect = 5e-28 Identities = 76/306 (24%), Positives = 147/306 (48%), Gaps = 7/306 (2%) Query: 59 WMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISIVNQVSGY 118 ++ + S F NG VL + + KK P + +NLAV DL +V+ +I++ Sbjct: 39 YLTIIGILSTFGNGYVLYMSSRRKKKLRPAEIMTINLAVCDLGISVVGKPFTIISCFCHR 98 Query: 119 FVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNVRFDAKLAIVGIAFSWI 178 +V G C G+ G L ++ +S +R+L +C V K A + +A W Sbjct: 99 WVFGWIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKICYLSYGVWLKRKHAYICLAAIWA 158 Query: 179 WSAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIMLC 238 +++ WT P+ G Y P TSC D + + G Q +++ ++ C ++P A+I+ Sbjct: 159 YASFWTTMPLVGLGDYVPEPFGTSCTLDWWLAQASVGGQVFILNILFFCLLLPTAVIVFS 218 Query: 239 YLQVWLAIRAVAKQ----QKESESTQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAAN 294 Y+++ +++ +K+ S+ E ++T++ +++ + + W PY + ++A Sbjct: 219 YVKIIAKVKSSSKEVAHFDSRIHSSHVLEMKLTKVAMLICAGFLIAWIPYAVVSVWSAFG 278 Query: 295 PGYAFHPLMAALPAYFAKSATIYNPVIYVFMNRQFRNCI---LQLFGKKVDDGSELSSAS 351 + ++ +P AKSA +YNP+IY ++ +F C L+ KK +G L + + Sbjct: 279 RPDSIPIQLSVVPTLLAKSAAMYNPIIYQVIDYKFACCQTGGLKATKKKSLEGFRLHTVT 338 Query: 352 KTEVSS 357 SS Sbjct: 339 TVRKSS 344 >gi|5174593 melatonin receptor 1A [Homo sapiens] Length = 350 Score = 95.9 bits (237), Expect = 5e-20 Identities = 67/291 (23%), Positives = 135/291 (46%), Gaps = 19/291 (6%) Query: 49 PRWVYHLTSVWMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIAST 108 P W+ + +IF + + N LV+ + + KKLR+ N +V+LAVADL + Sbjct: 23 PSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYP 82 Query: 109 ISIVNQVSGYFVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFG-NVRFDAK 167 + +++ + + LG+ C + G+ + L I ++++ I+ R+ +C + + +K Sbjct: 83 LVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSK 142 Query: 168 LAIVGIAFSWIWSAVWTAPPI-FGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVT 226 ++ + W+ + P + G +Y P + V S +Y I ++V Sbjct: 143 NSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSS--------AYTIAVVVF 194 Query: 227 CCIIPLAIIMLCYLQVWLAIRAVAKQQKESESTQKAEKE----VTRMVVVMIFAYCVCWG 282 ++P+ I++ CYL++W+ + V ++ K + ++ VT VV ++FA +CW Sbjct: 195 HFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFA--ICWA 252 Query: 283 PYTFFACFAAANPGYAFHPL---MAALPAYFAKSATIYNPVIYVFMNRQFR 330 P F A++P + + Y A + N +IY +N+ FR Sbjct: 253 PLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFR 303 >gi|157426873 tachykinin receptor 2 [Homo sapiens] Length = 398 Score = 92.8 bits (229), Expect = 4e-19 Identities = 71/316 (22%), Positives = 137/316 (43%), Gaps = 14/316 (4%) Query: 23 TQSSIFTYTNSNSTRGPFEGPNYHIAPRWVYHLTSVWMIFVVTASVFTNGLVLAATMKFK 82 T+++I + SN+T G P W L + + +V +V N +V+ + + Sbjct: 8 TEANISSGPESNTT-----GITAFSMPSWQLALWATAYLALVLVAVTGNAIVIWIILAHR 62 Query: 83 KLRHPLNWILVNLAVADLAETVIASTISIVNQVSGYFVLGHPMCVLEGYTVSLCGITGLW 142 ++R N+ +VNLA+ADL + + V + G C + ++ Sbjct: 63 RMRTVTNYFIVNLALADLCMAAFNAAFNFVYASHNIWYFGRAFCYFQNLFPITAMFVSIY 122 Query: 143 SLAIISWERWLVVCKPFGNVRFDAKLAIVGIAFSWIWSAVWTAPPIFGWSRYWPHGLKTS 202 S+ I+ +R++ + PF R A IA W+ + +P F + G T Sbjct: 123 SMTAIAADRYMAIVHPF-QPRLSAPSTKAVIAGIWLVALALASPQCFYSTVTMDQG-ATK 180 Query: 203 CGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIMLCYLQVWLAI--RAVAKQQKESESTQ 260 C S + Y +V++ +PLA++ + Y + L + RAV Q + + Sbjct: 181 CVVAWPEDSGGKTLLLYHLVVIALIYFLPLAVMFVAYSVIGLTLWRRAVPGHQAHGANLR 240 Query: 261 --KAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAANPGYAFHPLMAALPA---YFAKSAT 315 +A K+ + +V+++ + +CW PY + + H + + + A S+T Sbjct: 241 HLQAMKKFVKTMVLVVLTFAICWLPYHLYFILGSFQEDIYCHKFIQQVYLALFWLAMSST 300 Query: 316 IYNPVIYVFMNRQFRN 331 +YNP+IY +N +FR+ Sbjct: 301 MYNPIIYCCLNHRFRS 316 >gi|39725940 opioid receptor, kappa 1 [Homo sapiens] Length = 380 Score = 87.4 bits (215), Expect = 2e-17 Identities = 76/298 (25%), Positives = 138/298 (46%), Gaps = 21/298 (7%) Query: 46 HIAPRWVYHLTSVWMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETV- 104 HI+P +T+V+ + V V N LV+ +++ K++ N + NLA+AD T Sbjct: 53 HISPAIPVIITAVYSVVFVVGLV-GNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTT 111 Query: 105 --IASTISIVNQVSGYFVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNV 162 ST+ ++N VL + ++ Y + T +++L ++S +R++ VC P + Sbjct: 112 MPFQSTVYLMNSWPFGDVLCKIVISIDYYNM----FTSIFTLTMMSVDRYIAVCHPVKAL 167 Query: 163 RFDA--KLAIVGIAFSWIWSAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYM 220 F K I+ I + S+V + + G ++ C F Y +M Sbjct: 168 DFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQ-FPDDDYSWWDLFM 226 Query: 221 -IVLMVTCCIIPLAIIMLCYLQVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMIFAYCV 279 I + + +IP+ II++CY + L +++V E + + +TR+V+V++ + V Sbjct: 227 KICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRR-ITRLVLVVVAVFVV 285 Query: 280 CWGPYTFFACFAAANPGYAFHPLMAALPAYFAKSATIY-----NPVIYVFMNRQFRNC 332 CW P F A G H AAL +Y+ A Y NP++Y F++ F+ C Sbjct: 286 CWTPIHIFILVEAL--GSTSHS-TAALSSYYFCIALGYTNSSLNPILYAFLDENFKRC 340 >gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens] Length = 432 Score = 87.0 bits (214), Expect = 2e-17 Identities = 74/319 (23%), Positives = 133/319 (41%), Gaps = 62/319 (19%) Query: 60 MIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETV-IASTISIVNQVSGY 118 + + ++ N LV+ + KKLR P N+++V+LA+ADL+ V + +S+ + + G Sbjct: 88 LTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGK 147 Query: 119 FVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGN-VRFDAKLAIVGIAFSW 177 ++ GH C + +C + +L +IS +R+L + +P VR + K I W Sbjct: 148 WIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVW 207 Query: 178 IWSAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIML 237 + SA T PP+FGW++ D Y I IP+++++ Sbjct: 208 LLSASITLPPLFGWAQNVNDDKVCLISQDF----------GYTIYSTAVAFYIPMSVMLF 257 Query: 238 CYLQVW-----------------------LAIRAVAKQQKESE----------------S 258 Y Q++ +A+ + K QKE E S Sbjct: 258 MYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLKHERKNIS 317 Query: 259 TQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAANPGYAFHPLMAALPAYFAK------ 312 K E++ + +++ A+ VCW P F + A P + + +P + + Sbjct: 318 IFKREQKAATTLGIIVGAFTVCWLP---FFLLSTARP-FICGTSCSCIPLWVERTFLWLG 373 Query: 313 -SATIYNPVIYVFMNRQFR 330 + ++ NP IY F NR R Sbjct: 374 YANSLINPFIYAFFNRDLR 392 >gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens] Length = 479 Score = 87.0 bits (214), Expect = 2e-17 Identities = 74/319 (23%), Positives = 133/319 (41%), Gaps = 62/319 (19%) Query: 60 MIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETV-IASTISIVNQVSGY 118 + + ++ N LV+ + KKLR P N+++V+LA+ADL+ V + +S+ + + G Sbjct: 88 LTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGK 147 Query: 119 FVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGN-VRFDAKLAIVGIAFSW 177 ++ GH C + +C + +L +IS +R+L + +P VR + K I W Sbjct: 148 WIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVW 207 Query: 178 IWSAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIML 237 + SA T PP+FGW++ D Y I IP+++++ Sbjct: 208 LLSASITLPPLFGWAQNVNDDKVCLISQDF----------GYTIYSTAVAFYIPMSVMLF 257 Query: 238 CYLQVW-----------------------LAIRAVAKQQKESE----------------S 258 Y Q++ +A+ + K QKE E S Sbjct: 258 MYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLKHERKNIS 317 Query: 259 TQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAANPGYAFHPLMAALPAYFAK------ 312 K E++ + +++ A+ VCW P F + A P + + +P + + Sbjct: 318 IFKREQKAATTLGIIVGAFTVCWLP---FFLLSTARP-FICGTSCSCIPLWVERTFLWLG 373 Query: 313 -SATIYNPVIYVFMNRQFR 330 + ++ NP IY F NR R Sbjct: 374 YANSLINPFIYAFFNRDLR 392 >gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens] Length = 445 Score = 87.0 bits (214), Expect = 2e-17 Identities = 74/319 (23%), Positives = 133/319 (41%), Gaps = 62/319 (19%) Query: 60 MIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETV-IASTISIVNQVSGY 118 + + ++ N LV+ + KKLR P N+++V+LA+ADL+ V + +S+ + + G Sbjct: 88 LTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGK 147 Query: 119 FVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGN-VRFDAKLAIVGIAFSW 177 ++ GH C + +C + +L +IS +R+L + +P VR + K I W Sbjct: 148 WIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVW 207 Query: 178 IWSAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIML 237 + SA T PP+FGW++ D Y I IP+++++ Sbjct: 208 LLSASITLPPLFGWAQNVNDDKVCLISQDF----------GYTIYSTAVAFYIPMSVMLF 257 Query: 238 CYLQVW-----------------------LAIRAVAKQQKESE----------------S 258 Y Q++ +A+ + K QKE E S Sbjct: 258 MYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLKHERKNIS 317 Query: 259 TQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAANPGYAFHPLMAALPAYFAK------ 312 K E++ + +++ A+ VCW P F + A P + + +P + + Sbjct: 318 IFKREQKAATTLGIIVGAFTVCWLP---FFLLSTARP-FICGTSCSCIPLWVERTFLWLG 373 Query: 313 -SATIYNPVIYVFMNRQFR 330 + ++ NP IY F NR R Sbjct: 374 YANSLINPFIYAFFNRDLR 392 >gi|4507343 tachykinin receptor 1 isoform long [Homo sapiens] Length = 407 Score = 86.3 bits (212), Expect = 4e-17 Identities = 66/295 (22%), Positives = 123/295 (41%), Gaps = 10/295 (3%) Query: 43 PNYHIAPRWVYHLTSVWMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAE 102 PN + P W L + +V SV N +V+ + K++R N+ LVNLA A+ + Sbjct: 22 PNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASM 81 Query: 103 TVIASTISIVNQVSGYFVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNV 162 + ++ V + G C + ++S+ ++++R++ + P Sbjct: 82 AAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPL-QP 140 Query: 163 RFDAKLAIVGIAFSWIWSAVWTAPP-IFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMI 221 R A V I W+ + + P + + P + Y V Y I Sbjct: 141 RLSATATKVVICVIWVLALLLAFPQGYYSTTETMPSRVVCMIEWPEHPNKIYEKV--YHI 198 Query: 222 VLMVTCCIIPLAIIMLCYLQVWLAIRAVAKQQKESESTQK---AEKEVTRMVVVMIFAYC 278 + V +PL +I Y V + + A S+ + A+++V +M++V++ + Sbjct: 199 CVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFA 258 Query: 279 VCWGPYTFFACFAAANPGY---AFHPLMAALPAYFAKSATIYNPVIYVFMNRQFR 330 +CW P+ F NP F + + A S+T+YNP+IY +N +FR Sbjct: 259 ICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLNDRFR 313 >gi|7669548 tachykinin receptor 3 [Homo sapiens] Length = 465 Score = 85.5 bits (210), Expect = 7e-17 Identities = 62/294 (21%), Positives = 129/294 (43%), Gaps = 12/294 (4%) Query: 44 NYHIAPRWVYHLTSVWMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAET 103 N + P W L S+ VV +V N +V+ + K++R N+ LVNLA +D + Sbjct: 76 NQFVQPSWRIALWSLAYGVVVAVAVLGNLIVIWIILAHKRMRTVTNYFLVNLAFSDASMA 135 Query: 104 VIASTISIVNQVSGYFVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNVR 163 + ++ + + + G C + + ++S+ I+ +R++ + P R Sbjct: 136 AFNTLVNFIYALHSEWYFGANYCRFQNFFPITAVFASIYSMTAIAVDRYMAIIDPL-KPR 194 Query: 164 FDAKLAIVGIAFSWIWSAVWTAPP-IFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIV 222 A + I WI + + P ++ ++ P +T C G +++ Sbjct: 195 LSATATKIVIGSIWILAFLLAFPQCLYSKTKVMPG--RTLCFVQWPEGPKQHFTYHIIVI 252 Query: 223 LMVTCCIIPLAIIMLCYLQVWLAI---RAVAKQQKESESTQKAEKEVTRMVVVMIFAYCV 279 ++V C PL I+ + Y V + + + KA+++V +M+++++ + + Sbjct: 253 ILVYC--FPLLIMGITYTIVGITLWGGEIPGDTCDKYHEQLKAKRKVVKMMIIVVMTFAI 310 Query: 280 CWGPYTFFACFAAANP---GYAFHPLMAALPAYFAKSATIYNPVIYVFMNRQFR 330 CW PY + A + + + + A S+T+YNP+IY +N++FR Sbjct: 311 CWLPYHIYFILTAIYQQLNRWKYIQQVYLASFWLAMSSTMYNPIIYCCLNKRFR 364 >gi|150170722 G protein-coupled receptor 50 [Homo sapiens] Length = 617 Score = 84.7 bits (208), Expect = 1e-16 Identities = 64/276 (23%), Positives = 119/276 (43%), Gaps = 13/276 (4%) Query: 60 MIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISIVNQVSGYF 119 M+ + + N +V+ A K KKLR+ N +V+L+VAD+ + + + G + Sbjct: 35 MVITIVVDLIGNSMVILAVTKNKKLRNSGNIFVVSLSVADMLVAIYPYPLMLHAMSIGGW 94 Query: 120 VLGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNVR-FDAKLAIVGIAFSWI 178 L C + G+ L + ++++ I+ R+ +C R F + + + +WI Sbjct: 95 DLSQLQCQMVGFITGLSVVGSIFNIVAIAINRYCYICHSLQYERIFSVRNTCIYLVITWI 154 Query: 179 WSAVWTAPPIF-GWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIML 237 + + P ++ G Y P +C +F+ + P + + ++ ++PL I+ Sbjct: 155 MTVLAVLPNMYIGTIEYDPR--TYTC---IFNYLNNP---VFTVTIVCIHFVLPLLIVGF 206 Query: 238 CYLQVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAANPGY 297 CY+++W + A ++ Q AE + V+ + VCW P A +P Sbjct: 207 CYVRIWTKVLAARDPAGQNPDNQLAEVRNFLTMFVIFLLFAVCWCPINVLTVLVAVSPKE 266 Query: 298 AFH--PLMAALPAYF-AKSATIYNPVIYVFMNRQFR 330 P L AYF A + N VIY +N FR Sbjct: 267 MAGKIPNWLYLAAYFIAYFNSCLNAVIYGLLNENFR 302 >gi|21264324 trace amine associated receptor 1 [Homo sapiens] Length = 339 Score = 84.3 bits (207), Expect = 2e-16 Identities = 70/308 (22%), Positives = 134/308 (43%), Gaps = 43/308 (13%) Query: 60 MIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISIVNQVSGYF 119 M+ ++ ++ N +V+ + FK+L P NW++ ++A D + S+V + Sbjct: 30 MVLIILTTLVGNLIVIVSISHFKQLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHCW 89 Query: 120 VLGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNVRFDAKLAIVGIAFSWIW 179 G C + T + ++ L+ IS +R+ VC P +R+ AK+ I+ I Sbjct: 90 YFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVCDP---LRYKAKMNILVICVMIFI 146 Query: 180 SAVWTAPPIFGWSR-------------YWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVT 226 S W+ P +F + Y+ H + G VF S GV ++M T Sbjct: 147 S--WSVPAVFAFGMIFLELNFKGAEEIYYKH-VHCRGGCSVFF-SKISGVLTFM-----T 197 Query: 227 CCIIPLAIIMLCYLQVWLAIRAVAKQQKESES------------TQKAEKEVTRMVVVMI 274 IP +I++ Y +++L + A+ ++ +Q E++ + + +++ Sbjct: 198 SFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNGISQSKERKAVKTLGIVM 257 Query: 275 FAYCVCWGPYTFFACFAAANP--GYAFHPLMAALPAYFAKSATIYNPVIYVFMNRQFRNC 332 + +CW P FF C +P Y P + + +F + +NP++Y F FR Sbjct: 258 GVFLICWCP--FFIC-TVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFRKA 314 Query: 333 I-LQLFGK 339 + + LFGK Sbjct: 315 LKMMLFGK 322 >gi|7669546 tachykinin receptor 1 isoform short [Homo sapiens] Length = 311 Score = 82.4 bits (202), Expect = 6e-16 Identities = 64/291 (21%), Positives = 120/291 (41%), Gaps = 10/291 (3%) Query: 43 PNYHIAPRWVYHLTSVWMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAE 102 PN + P W L + +V SV N +V+ + K++R N+ LVNLA A+ + Sbjct: 22 PNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASM 81 Query: 103 TVIASTISIVNQVSGYFVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNV 162 + ++ V + G C + ++S+ ++++R++ + P Sbjct: 82 AAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPL-QP 140 Query: 163 RFDAKLAIVGIAFSWIWSAVWTAPP-IFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMI 221 R A V I W+ + + P + + P + Y V Y I Sbjct: 141 RLSATATKVVICVIWVLALLLAFPQGYYSTTETMPSRVVCMIEWPEHPNKIYEKV--YHI 198 Query: 222 VLMVTCCIIPLAIIMLCYLQVWLAIRAVAKQQKESESTQK---AEKEVTRMVVVMIFAYC 278 + V +PL +I Y V + + A S+ + A+++V +M++V++ + Sbjct: 199 CVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFA 258 Query: 279 VCWGPYTFFACFAAANPGY---AFHPLMAALPAYFAKSATIYNPVIYVFMN 326 +CW P+ F NP F + + A S+T+YNP+IY +N Sbjct: 259 ICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLN 309 >gi|5174595 melatonin receptor 1B [Homo sapiens] Length = 362 Score = 82.0 bits (201), Expect = 8e-16 Identities = 73/294 (24%), Positives = 125/294 (42%), Gaps = 25/294 (8%) Query: 49 PRWVYHLTSVWMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIAST 108 P WV S +I V N LV+ + ++ +KLR+ N LV+LA+ADL Sbjct: 36 PPWVAPALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYP 95 Query: 109 ISIVNQVSGYFVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNVRFDAKL 168 + +V + LG C + + L I ++++ I+ R+ +C R + Sbjct: 96 LILVAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRW 155 Query: 169 -AIVGIAFSWIWSAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQS-YMIVLMVT 226 + I W+ + V P F S + P ++S + + Y ++V Sbjct: 156 HTPLHICLIWLLTVVALLPNFFVGSLEY--------DPRIYSCTFIQTASTQYTAAVVVI 207 Query: 227 CCIIPLAIIMLCYLQVW-LAIRAVAKQQKESESTQK---AEKEVTRMVVVMIFAYCVCWG 282 ++P+A++ CYL++W L ++A K + ES K +T VV +IFA +CW Sbjct: 208 HFLLPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTMFVVFVIFA--ICWA 265 Query: 283 PYTFFACFAAANPGYAFHPL------MAALPAYFAKSATIYNPVIYVFMNRQFR 330 P A NP + + L AYF + N ++Y +N+ FR Sbjct: 266 PLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYF---NSCLNAIVYGLLNQNFR 316 >gi|223633971 G protein-coupled receptor 83 [Homo sapiens] Length = 423 Score = 81.3 bits (199), Expect = 1e-15 Identities = 64/278 (23%), Positives = 128/278 (46%), Gaps = 13/278 (4%) Query: 62 FVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISIVNQVSGYFVL 121 F++ S+F N LV K +++ + +VNLAVAD+ T++ + ++V V+ ++ Sbjct: 80 FIIVFSLFGNVLVCHVIFKNQRMHSATSLFIVNLAVADIMITLLNTPFTLVRFVNSTWIF 139 Query: 122 GHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNVRFDAKLAIVGIAFSWIWSA 181 G MC + + +L I+ +R V+ P R ++ IA W + Sbjct: 140 GKGMCHVSRFAQYCSLHVSALTLTAIAVDRHQVIMHPL-KPRISITKGVIYIAVIWTMAT 198 Query: 182 VWTAP-----PIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIM 236 ++ P +F + +Y +++ C PD F + + + + I+PL II Sbjct: 199 FFSLPHAICQKLFTF-KYSEDIVRSLCLPD-FPEPADLFWKYLDLATFILLYILPLLIIS 256 Query: 237 LCYLQV----WLAIRAVAKQQKESESTQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAA 292 + Y +V WL ++ + ++ +K+ +M+++++ + +CW P + + Sbjct: 257 VAYARVAKKLWLCNMIGDVTTEQYFALRRKKKKTIKMLMLVVVLFALCWFPLNCYVLLLS 316 Query: 293 ANPGYAFHPLMAALPAYFAKSATIYNPVIYVFMNRQFR 330 + + L A +FA S+T YNP IY ++N FR Sbjct: 317 SKVIRTNNALYFAF-HWFAMSSTCYNPFIYCWLNENFR 353 >gi|4557859 somatostatin receptor 2 [Homo sapiens] Length = 369 Score = 80.1 bits (196), Expect = 3e-15 Identities = 90/374 (24%), Positives = 163/374 (43%), Gaps = 48/374 (12%) Query: 10 LAGRHPQDSYEDSTQSSIFTYTNSNSTRGPFEGPNYHIAPRWVYHLTSVWMIFVVTASVF 69 L G H S S+ + SN T P Y + V LT ++ + V + Sbjct: 8 LNGSHTWLSIPFDLNGSVVSTNTSNQTE-----PYYDLTSNAV--LTFIYFV-VCIIGLC 59 Query: 70 TNGLVLAATMKFKKLRHPLNWILVNLAVAD----LAETVIASTISIVNQVSGYFVLGHPM 125 N LV+ +++ K++ N ++NLA+AD L +A +++V ++ G + Sbjct: 60 GNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALV-----HWPFGKAI 114 Query: 126 CVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNVRFDAKLAIVGIAFSWIWSAVWTA 185 C + + T ++ L ++S +R+L V P + ++ I + ++ Sbjct: 115 CRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSLLVI 174 Query: 186 PPIFGW----SRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIMLCYLQ 241 PI + S W T P SG+ Y G Y +L ++PL II LCYL Sbjct: 175 LPIMIYAGLRSNQWGRSSCTINWPGE-SGAWYTGFIIYTFILGF---LVPLTIICLCYLF 230 Query: 242 VWLAIRAVAKQQKESESTQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAANPGYAFHP 301 + + +++ + S+ +K+EK+VTRMV +++ + CW P F F ++ A P Sbjct: 231 IIIKVKSSGIRVGSSKR-KKSEKKVTRMVSIVVAVFIFCWLP---FYIFNVSSVSMAISP 286 Query: 302 LMAALPAY-------FAKSATIYNPVIYVFMNRQFRN------CILQLFGKKVDDGSELS 348 A + +A S NP++Y F++ F+ C++++ G DDG Sbjct: 287 TPALKGMFDFVVVLTYANSCA--NPILYAFLSDNFKKSFQNVLCLVKVSG--TDDGER-- 340 Query: 349 SASKTEVSSVSSVS 362 S SK + S ++ + Sbjct: 341 SDSKQDKSRLNETT 354 >gi|223633986 trace amine associated receptor 5 [Homo sapiens] Length = 337 Score = 80.1 bits (196), Expect = 3e-15 Identities = 69/295 (23%), Positives = 130/295 (44%), Gaps = 12/295 (4%) Query: 52 VYHLTSVWMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISI 111 +Y + M+ +V +VF V A FK L P N++L++LA+AD+ ++ +S Sbjct: 37 IYLACAAGMLIIVLGNVF----VAFAVSYFKALHTPTNFLLLSLALADMFLGLLVLPLST 92 Query: 112 VNQVSGYFVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKP-FGNVRFDAKLAI 170 + V + G +C L Y +L +T ++ L IS +R +C P +F ++A+ Sbjct: 93 IRSVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCAICDPLLYPSKFTVRVAL 152 Query: 171 VGIAFSWIWSAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCII 230 I W A +T+ +F ++ L GS + + L + Sbjct: 153 RYILAGWGVPAAYTS--LFLYTDVVETRLSQWLEEMPCVGSCQLLLNKFWGWLNFPLFFV 210 Query: 231 PLAIIMLCYLQVWLAIRAVAKQ----QKESESTQKAEKEVTRMVVVMIFAYCVCWGPYTF 286 P I++ Y+++++ A+Q K K E++ + + + + Y +CW P+T Sbjct: 211 PCLIMISLYVKIFVVATRQAQQITTLSKSLAGAAKHERKAAKTLGIAVGIYLLCWLPFT- 269 Query: 287 FACFAAANPGYAFHPLMAALPAYFAKSATIYNPVIYVFMNRQFRNCILQLFGKKV 341 + + PL+ + +FA + NP+IYVF + FR + +KV Sbjct: 270 IDTMVDSLLHFITPPLVFDIFIWFAYFNSACNPIIYVFSYQWFRKALKLTLSQKV 324 >gi|4557865 somatostatin receptor 5 [Homo sapiens] Length = 364 Score = 79.0 bits (193), Expect = 6e-15 Identities = 77/304 (25%), Positives = 137/304 (45%), Gaps = 23/304 (7%) Query: 55 LTSVWMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISIVNQ 114 L V + V A + N LV+ ++F K++ N ++NLAVAD+ + ++ N Sbjct: 42 LVPVLYLLVCAAGLGGNTLVIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNA 101 Query: 115 VSGYFVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNVRFDA-KLAIVGI 173 S ++ G +C L + T ++ L ++S +R+L V P + R+ ++A + Sbjct: 102 AS-FWPFGPVLCRLVMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLAS 160 Query: 174 AFSWIWSAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLA 233 A +W+ S + P + ++ G + P+ + V ++I V PL Sbjct: 161 AAAWVLSLCMSLP-LLVFADVQEGGTCNASWPEPVG--LWGAV--FIIYTAVLGFFAPLL 215 Query: 234 IIMLCYLQVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAA 293 +I LCYL + + +RA + +++E++VTRMV+V++ + CW P F Sbjct: 216 VICLCYLLIVVKVRAAGV--RVGCVRRRSERKVTRMVLVVVLVFAGCWLP---FFTVNIV 270 Query: 294 NPGYAFHPLMAALPAYFAKSATIY-----NPVIYVFMNRQFRN------CILQLFGKKVD 342 N A A+ YF Y NPV+Y F++ FR C+ + G K Sbjct: 271 NLAVALPQEPASAGLYFFVVILSYANSCANPVLYGFLSDNFRQSFQKVLCLRKGSGAKDA 330 Query: 343 DGSE 346 D +E Sbjct: 331 DATE 334 >gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens] Length = 493 Score = 79.0 bits (193), Expect = 6e-15 Identities = 67/276 (24%), Positives = 124/276 (44%), Gaps = 13/276 (4%) Query: 63 VVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISI--VNQVSGYFV 120 V +F N LV+ +++ K++ N + NLA+AD T ST+ VN + G + Sbjct: 173 VCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT---STLPFQSVNYLMGTWP 229 Query: 121 LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNVRFDA--KLAIVGIAFSWI 178 G +C + T +++L +S +R++ VC P + F I+ + +WI Sbjct: 230 FGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVC-NWI 288 Query: 179 WSAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIMLC 238 S+ P +F + + G C FS ++ I + + I+P+ II +C Sbjct: 289 LSSAIGLPVMFMATTKYRQG-SIDCTL-TFSHPTWYWENLLKICVFIFAFIMPVLIITVC 346 Query: 239 YLQVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAA--ANPG 296 Y + L +++V + S+ + + +TRMV+V++ + VCW P + A P Sbjct: 347 YGLMILRLKSV-RMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPE 405 Query: 297 YAFHPLMAALPAYFAKSATIYNPVIYVFMNRQFRNC 332 F + + + NPV+Y F++ F+ C Sbjct: 406 TTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRC 441 >gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens] Length = 400 Score = 79.0 bits (193), Expect = 6e-15 Identities = 67/276 (24%), Positives = 124/276 (44%), Gaps = 13/276 (4%) Query: 63 VVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISI--VNQVSGYFV 120 V +F N LV+ +++ K++ N + NLA+AD T ST+ VN + G + Sbjct: 80 VCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT---STLPFQSVNYLMGTWP 136 Query: 121 LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNVRFDA--KLAIVGIAFSWI 178 G +C + T +++L +S +R++ VC P + F I+ + +WI Sbjct: 137 FGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVC-NWI 195 Query: 179 WSAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIMLC 238 S+ P +F + + G C FS ++ I + + I+P+ II +C Sbjct: 196 LSSAIGLPVMFMATTKYRQG-SIDCTL-TFSHPTWYWENLLKICVFIFAFIMPVLIITVC 253 Query: 239 YLQVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAA--ANPG 296 Y + L +++V + S+ + + +TRMV+V++ + VCW P + A P Sbjct: 254 YGLMILRLKSV-RMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPE 312 Query: 297 YAFHPLMAALPAYFAKSATIYNPVIYVFMNRQFRNC 332 F + + + NPV+Y F++ F+ C Sbjct: 313 TTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRC 348 >gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens] Length = 420 Score = 79.0 bits (193), Expect = 6e-15 Identities = 67/276 (24%), Positives = 124/276 (44%), Gaps = 13/276 (4%) Query: 63 VVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISI--VNQVSGYFV 120 V +F N LV+ +++ K++ N + NLA+AD T ST+ VN + G + Sbjct: 80 VCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT---STLPFQSVNYLMGTWP 136 Query: 121 LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNVRFDA--KLAIVGIAFSWI 178 G +C + T +++L +S +R++ VC P + F I+ + +WI Sbjct: 137 FGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVC-NWI 195 Query: 179 WSAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIMLC 238 S+ P +F + + G C FS ++ I + + I+P+ II +C Sbjct: 196 LSSAIGLPVMFMATTKYRQG-SIDCTL-TFSHPTWYWENLLKICVFIFAFIMPVLIITVC 253 Query: 239 YLQVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAA--ANPG 296 Y + L +++V + S+ + + +TRMV+V++ + VCW P + A P Sbjct: 254 YGLMILRLKSV-RMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPE 312 Query: 297 YAFHPLMAALPAYFAKSATIYNPVIYVFMNRQFRNC 332 F + + + NPV+Y F++ F+ C Sbjct: 313 TTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRC 348 >gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens] Length = 397 Score = 79.0 bits (193), Expect = 6e-15 Identities = 67/276 (24%), Positives = 124/276 (44%), Gaps = 13/276 (4%) Query: 63 VVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISI--VNQVSGYFV 120 V +F N LV+ +++ K++ N + NLA+AD T ST+ VN + G + Sbjct: 80 VCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT---STLPFQSVNYLMGTWP 136 Query: 121 LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNVRFDA--KLAIVGIAFSWI 178 G +C + T +++L +S +R++ VC P + F I+ + +WI Sbjct: 137 FGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVC-NWI 195 Query: 179 WSAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIMLC 238 S+ P +F + + G C FS ++ I + + I+P+ II +C Sbjct: 196 LSSAIGLPVMFMATTKYRQG-SIDCTL-TFSHPTWYWENLLKICVFIFAFIMPVLIITVC 253 Query: 239 YLQVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAA--ANPG 296 Y + L +++V + S+ + + +TRMV+V++ + VCW P + A P Sbjct: 254 YGLMILRLKSV-RMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPE 312 Query: 297 YAFHPLMAALPAYFAKSATIYNPVIYVFMNRQFRNC 332 F + + + NPV+Y F++ F+ C Sbjct: 313 TTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRC 348 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.325 0.135 0.443 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,641,257 Number of Sequences: 37866 Number of extensions: 557962 Number of successful extensions: 2965 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 311 Number of HSP's successfully gapped in prelim test: 303 Number of HSP's that attempted gapping in prelim test: 1977 Number of HSP's gapped (non-prelim): 749 length of query: 364 length of database: 18,247,518 effective HSP length: 104 effective length of query: 260 effective length of database: 14,309,454 effective search space: 3720458040 effective search space used: 3720458040 T: 11 A: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.