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Search of human proteins with 9910364
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|9910364 aspartate beta-hydroxylase isoform e [Homo sapiens]
(225 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|9910364 aspartate beta-hydroxylase isoform e [Homo sapiens] 448 e-126
gi|14589862 aspartate beta-hydroxylase isoform d [Homo sapiens] 410 e-115
gi|14589864 aspartate beta-hydroxylase isoform b [Homo sapiens] 203 1e-52
gi|14589860 aspartate beta-hydroxylase isoform c [Homo sapiens] 155 2e-38
gi|14589866 aspartate beta-hydroxylase isoform a [Homo sapiens] 155 2e-38
gi|104526627 triadin [Homo sapiens] 77 1e-14
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 61 7e-10
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 61 9e-10
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 61 9e-10
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 59 4e-09
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 57 1e-08
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 57 1e-08
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 54 1e-07
gi|4557509 cylicin 2 [Homo sapiens] 51 9e-07
gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens] 51 9e-07
gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens] 51 9e-07
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 50 1e-06
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 50 1e-06
gi|41055989 M-phase phosphoprotein 8 [Homo sapiens] 50 1e-06
gi|27734775 hypothetical protein LOC286499 [Homo sapiens] 50 2e-06
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 50 2e-06
gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo ... 50 2e-06
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 49 3e-06
gi|168229156 NFKB activating protein [Homo sapiens] 49 3e-06
gi|155030242 WD repeat domain 60 [Homo sapiens] 49 3e-06
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ... 49 3e-06
gi|125656165 THO complex 2 [Homo sapiens] 49 5e-06
gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo... 49 5e-06
gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo... 49 5e-06
gi|52426743 cisplatin resistance-associated overexpressed protei... 48 6e-06
>gi|9910364 aspartate beta-hydroxylase isoform e [Homo sapiens]
Length = 225
Score = 448 bits (1153), Expect = e-126
Identities = 225/225 (100%), Positives = 225/225 (100%)
Query: 1 MAEDKETKHGGHKNGRKGGLSGTSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVLAKAKD 60
MAEDKETKHGGHKNGRKGGLSGTSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVLAKAKD
Sbjct: 1 MAEDKETKHGGHKNGRKGGLSGTSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVLAKAKD 60
Query: 61 FRYNLSEVLQGKLGIYDADGDGDFDVDDAKVLLEGPSGVAKRKTKAKVKELTKEELKKEK 120
FRYNLSEVLQGKLGIYDADGDGDFDVDDAKVLLEGPSGVAKRKTKAKVKELTKEELKKEK
Sbjct: 61 FRYNLSEVLQGKLGIYDADGDGDFDVDDAKVLLEGPSGVAKRKTKAKVKELTKEELKKEK 120
Query: 121 EKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPKGKKDREKEKVDLEKSAKTKE 180
EKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPKGKKDREKEKVDLEKSAKTKE
Sbjct: 121 EKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPKGKKDREKEKVDLEKSAKTKE 180
Query: 181 NRKKSTNMKDVSSKMASRDKDDRKESRSSTRYAHLTKGNTQKRNG 225
NRKKSTNMKDVSSKMASRDKDDRKESRSSTRYAHLTKGNTQKRNG
Sbjct: 181 NRKKSTNMKDVSSKMASRDKDDRKESRSSTRYAHLTKGNTQKRNG 225
>gi|14589862 aspartate beta-hydroxylase isoform d [Homo sapiens]
Length = 210
Score = 410 bits (1053), Expect = e-115
Identities = 210/225 (93%), Positives = 210/225 (93%), Gaps = 15/225 (6%)
Query: 1 MAEDKETKHGGHKNGRKGGLSGTSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVLAKAKD 60
MAEDKETKHGGHKNGRKGGLSGTSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVL
Sbjct: 1 MAEDKETKHGGHKNGRKGGLSGTSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVL----- 55
Query: 61 FRYNLSEVLQGKLGIYDADGDGDFDVDDAKVLLEGPSGVAKRKTKAKVKELTKEELKKEK 120
GKLGIYDADGDGDFDVDDAKVLLEGPSGVAKRKTKAKVKELTKEELKKEK
Sbjct: 56 ----------GKLGIYDADGDGDFDVDDAKVLLEGPSGVAKRKTKAKVKELTKEELKKEK 105
Query: 121 EKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPKGKKDREKEKVDLEKSAKTKE 180
EKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPKGKKDREKEKVDLEKSAKTKE
Sbjct: 106 EKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPKGKKDREKEKVDLEKSAKTKE 165
Query: 181 NRKKSTNMKDVSSKMASRDKDDRKESRSSTRYAHLTKGNTQKRNG 225
NRKKSTNMKDVSSKMASRDKDDRKESRSSTRYAHLTKGNTQKRNG
Sbjct: 166 NRKKSTNMKDVSSKMASRDKDDRKESRSSTRYAHLTKGNTQKRNG 210
>gi|14589864 aspartate beta-hydroxylase isoform b [Homo sapiens]
Length = 299
Score = 203 bits (516), Expect = 1e-52
Identities = 107/175 (61%), Positives = 128/175 (73%), Gaps = 10/175 (5%)
Query: 1 MAEDKETKHGGHKNGRKGGLSGTSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVLAKAKD 60
MAEDKETKHGGHKNGRKGGLSGTSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVLAKAKD
Sbjct: 1 MAEDKETKHGGHKNGRKGGLSGTSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVLAKAKD 60
Query: 61 FRYNLSEVLQGKLGIYDADGDGDFDVDDAKVLLEGPSGVAKRKTK--AKVKELTKEELKK 118
FRYNLSEVLQGKLGIYDADGDGDFDVDDAKVLL G+ +R T A E + +
Sbjct: 61 FRYNLSEVLQGKLGIYDADGDGDFDVDDAKVLL----GLKERSTSEPAVPPEEAEPHTEP 116
Query: 119 EKEKPESRKESKNEERKKGKKEDVRKD----KKIADADLSRKESPKGKKDREKEK 169
E++ P + E+ K + + + + + + DL +++ P G+ +E ++
Sbjct: 117 EEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDE 171
>gi|14589860 aspartate beta-hydroxylase isoform c [Homo sapiens]
Length = 313
Score = 155 bits (393), Expect = 2e-38
Identities = 87/171 (50%), Positives = 109/171 (63%), Gaps = 25/171 (14%)
Query: 5 KETKHGGHKNGRKGGLSGTSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVLAKAKDFRYN 64
+ETKHGGHKNGRKGGLSGTSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVL
Sbjct: 34 RETKHGGHKNGRKGGLSGTSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVL--------- 84
Query: 65 LSEVLQGKLGIYDADGDGDFDVDDAKVLLEGPSGVAKRKTK--AKVKELTKEELKKEKEK 122
GKLGIYDADGDGDFDVDDAKVLL G+ +R T A E + + E++
Sbjct: 85 ------GKLGIYDADGDGDFDVDDAKVLL----GLKERSTSEPAVPPEEAEPHTEPEEQV 134
Query: 123 PESRKESKNEERKKGKKEDVRKD----KKIADADLSRKESPKGKKDREKEK 169
P + E+ K + + + + + + DL +++ P G+ +E ++
Sbjct: 135 PVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDE 185
>gi|14589866 aspartate beta-hydroxylase isoform a [Homo sapiens]
Length = 758
Score = 155 bits (393), Expect = 2e-38
Identities = 87/171 (50%), Positives = 109/171 (63%), Gaps = 25/171 (14%)
Query: 5 KETKHGGHKNGRKGGLSGTSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVLAKAKDFRYN 64
+ETKHGGHKNGRKGGLSGTSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVL
Sbjct: 34 RETKHGGHKNGRKGGLSGTSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVL--------- 84
Query: 65 LSEVLQGKLGIYDADGDGDFDVDDAKVLLEGPSGVAKRKTK--AKVKELTKEELKKEKEK 122
GKLGIYDADGDGDFDVDDAKVLL G+ +R T A E + + E++
Sbjct: 85 ------GKLGIYDADGDGDFDVDDAKVLL----GLKERSTSEPAVPPEEAEPHTEPEEQV 134
Query: 123 PESRKESKNEERKKGKKEDVRKD----KKIADADLSRKESPKGKKDREKEK 169
P + E+ K + + + + + + DL +++ P G+ +E ++
Sbjct: 135 PVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDE 185
Score = 28.9 bits (63), Expect = 3.7
Identities = 38/180 (21%), Positives = 82/180 (45%), Gaps = 23/180 (12%)
Query: 49 VDYEEVLAKAKDFRYNLSEVLQGKLGIYDADGDGDFDVDDAKVLLEGPSGVAKRKTKAKV 108
++ EV A +D S+V+ ++ I+ + + +V E + KAKV
Sbjct: 274 IEITEVTAPPEDNPVEDSQVIVEEVSIFPVE-------EQQEVPPETNRKTDDPEQKAKV 326
Query: 109 KELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRK--ESPKGKKDRE 166
K+ + L K + ++ ++ + RK+GK E+ A +L RK +SP+ + +
Sbjct: 327 KKKKPKLLNKFDKTIKAELDAAEKLRKRGKIEEAVN----AFKELVRKYPQSPRARYGKA 382
Query: 167 KEKVDLEKSAKTK-------ENRKKSTNMKDVSS---KMASRDKDDRKESRSSTRYAHLT 216
+ + DL + ++ E ++ ++ DV + K++ + + DR++ R + LT
Sbjct: 383 QCEDDLAEKRRSNEVLRGAIETYQEVASLPDVPADLLKLSLKRRSDRQQFLGHMRGSLLT 442
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 77.0 bits (188), Expect = 1e-14
Identities = 65/225 (28%), Positives = 103/225 (45%), Gaps = 42/225 (18%)
Query: 28 WFMVIALLGVWTSVAVVWFDLVDYE-------------------EVLAKAKDFRYNLSEV 68
W +VIAL+ W++VA+V FDLVDY+ + + + D+ Y +
Sbjct: 50 WLLVIALIITWSAVAIVMFDLVDYKNFSASSIAKIGSDPLKLVRDAMEETTDWIYGFFSL 109
Query: 69 LQGKLGIYD-ADGDGDFDVDDAKV----------------LLEGPSGVAKRKTKAKVKEL 111
L + D D DGD D D ++ E P + K K KE
Sbjct: 110 LSDIISSEDEEDDDGDEDTDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEK 169
Query: 112 TKEELKKEKEKPESRKESKNEERKKGKKED---VRKDKKIADADLSRKESPKGKKDREKE 168
KE++ +EKEKPE + K + KK K E ++ KK A+ S +++ K K ++E
Sbjct: 170 GKEKV-REKEKPEKKATHKEKIEKKEKPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQE 228
Query: 169 KVDLEKSAKTKENRKKSTNMKDVSSK-MASRDKDDRKESRSSTRY 212
KV + +AK KE +K + K+ K A+ K ++K+ + RY
Sbjct: 229 KVK-QTAAKVKEVQKTPSKPKEKEDKEKAAVSKHEQKDQYAFCRY 272
Score = 44.7 bits (104), Expect = 7e-05
Identities = 41/145 (28%), Positives = 63/145 (43%), Gaps = 34/145 (23%)
Query: 94 EGPSGVAKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKED------------ 141
EG A++K ++ K+ KE++KK+ EK + K E GK +
Sbjct: 313 EGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEP---GKASETKQGTVKIAAQA 369
Query: 142 -VRKDKKIADADLSRK----ESPKGKKDREKEK-------------VDLEKSAKTKENRK 183
+KD+K D+ ++K E PKGKK +KEK V +K K K R
Sbjct: 370 AAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERA 429
Query: 184 KSTNMKDVSSKMASRDKDDRKESRS 208
K + VS K A K + K +++
Sbjct: 430 KE-EIGAVSIKKAVPGKKEEKTTKT 453
Score = 40.8 bits (94), Expect = 0.001
Identities = 33/122 (27%), Positives = 55/122 (45%), Gaps = 17/122 (13%)
Query: 98 GVAKRKTKAKVKELTKEELKKEKEKPESRKESK--NEERKKGKKEDVRKDKKIADADLSR 155
G A + VK + KK+++K +S+K K E+ KGKK++ +K+K + A +
Sbjct: 353 GKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQE-KKEKHVEPAKSPK 411
Query: 156 KE-------SPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRS 208
KE K K +R KE++ K +K+ K V +++ RKE
Sbjct: 412 KEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTV-------EQEIRKEKSG 464
Query: 209 ST 210
T
Sbjct: 465 KT 466
Score = 40.8 bits (94), Expect = 0.001
Identities = 32/117 (27%), Positives = 56/117 (47%), Gaps = 16/117 (13%)
Query: 103 KTKAKVKELTKEELKKEK----------EKPESRKESKNEERKKGKKEDVRKDKKIADAD 152
K + K + ++E++KEK ++P KE K K K+ + +KD+K++ A
Sbjct: 445 KKEEKTTKTVEQEIRKEKSGKTSSILKDKEPIKGKEEKVPASLKEKEPETKKDEKMSKAG 504
Query: 153 LSRKESP---KGKKDREKEKVDLEKSAKTKENRKKSTNMKDV--SSKMASRDKDDRK 204
K P +GKK+ EK + ++K AK + K + +D+ K S K + K
Sbjct: 505 KEVKPKPPQLQGKKE-EKPEPQIKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEEK 560
Score = 39.7 bits (91), Expect = 0.002
Identities = 23/91 (25%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
Query: 117 KKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPKGKKDREKEKVDLEKSA 176
+KE EK ++ K+ +E +KK K++ +K +K D+ +KE K + ++ V + A
Sbjct: 311 EKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPGKASETKQ-GTVKIAAQA 369
Query: 177 KTKENRKKSTNMKDVSSKMASRDKDDRKESR 207
K++ KK + K + K ++E +
Sbjct: 370 AAKKDEKKEDSKKTKKPAEVEQPKGKKQEKK 400
Score = 37.0 bits (84), Expect = 0.014
Identities = 34/135 (25%), Positives = 62/135 (45%), Gaps = 17/135 (12%)
Query: 100 AKRKTKAKVKELTKE--ELKKEKEKPESRKESKNEERKKGKKE-DVRKDKKIAD------ 150
AK+ K + + TK+ E+++ K K + +KE E K KKE V DK++
Sbjct: 371 AKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAK 430
Query: 151 ---ADLSRKESPKGKKDRE-----KEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDD 202
+S K++ GKK+ + ++++ EKS KT K +K K+ + K+
Sbjct: 431 EEIGAVSIKKAVPGKKEEKTTKTVEQEIRKEKSGKTSSILKDKEPIKGKEEKVPASLKEK 490
Query: 203 RKESRSSTRYAHLTK 217
E++ + + K
Sbjct: 491 EPETKKDEKMSKAGK 505
Score = 35.4 bits (80), Expect = 0.040
Identities = 41/156 (26%), Positives = 63/156 (40%), Gaps = 48/156 (30%)
Query: 102 RKTKAKVKELTKEELK-KEKEKPESRKESKNEER------------------KKGKK--- 139
++T AKVKE+ K K KEKE E SK+E++ K G+
Sbjct: 231 KQTAAKVKEVQKTPSKPKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAI 290
Query: 140 -------------------EDVRKDKKIAD----ADLSRKESPKGKKDREKE-KVDLEKS 175
E+ +KK A+ ++ +KE KK EKE +D+EK
Sbjct: 291 PPPLPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKK 350
Query: 176 AKTKENRKKSTNMKDVSSKMASRDKDDRKESRSSTR 211
K + K +K + A+ KD++KE T+
Sbjct: 351 EPGKASETKQGTVK--IAAQAAAKKDEKKEDSKKTK 384
Score = 35.4 bits (80), Expect = 0.040
Identities = 31/110 (28%), Positives = 57/110 (51%), Gaps = 4/110 (3%)
Query: 86 VDDAKVLLEGPSGVAKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKD 145
V+ AK + S + ++ KAK E KEE+ K ++ K E+ K ++++RK+
Sbjct: 404 VEPAKSPKKEHSVPSDKQVKAKT-ERAKEEIGAVSIK-KAVPGKKEEKTTKTVEQEIRKE 461
Query: 146 KKIADADLSRKESP-KGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSK 194
K + + + + P KGK+++ + EK +TK++ K S K+V K
Sbjct: 462 KSGKTSSILKDKEPIKGKEEKVPASLK-EKEPETKKDEKMSKAGKEVKPK 510
Score = 35.0 bits (79), Expect = 0.052
Identities = 28/114 (24%), Positives = 53/114 (46%), Gaps = 7/114 (6%)
Query: 99 VAKRKTKAKVKELTKEELKKEKEKPESRKESKN--EERKKGKKEDVRKDKKIADADLSRK 156
++K + K K + K+EK +P+ +KE+K E+ + K+D+ K +K
Sbjct: 500 MSKAGKEVKPKPPQLQGKKEEKPEPQIKKEAKPAISEKVQIHKQDIVKPEKTVS-----H 554
Query: 157 ESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSST 210
P+ K ++ + V +EK+AK K +K ++ S + K K + T
Sbjct: 555 GKPEEKVLKQVKAVTIEKTAKPKPTKKAEHREREPPSIKTDKPKPTPKGTSEVT 608
Score = 33.9 bits (76), Expect = 0.12
Identities = 28/107 (26%), Positives = 50/107 (46%), Gaps = 8/107 (7%)
Query: 100 AKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKE---DVRKDKKIADADLSRK 156
AK K K + +E + +KP+ + +E + GKK+ ++ K+ AD R+
Sbjct: 574 AKPKPTKKAEHREREPPSIKTDKPKPTPKGTSEVTESGKKKTEISEKESKEKADMKHLRE 633
Query: 157 ESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDV-SSKMASRDKDD 202
E K KE + L K ++ + S +++DV +SK A +D
Sbjct: 634 E----KVSTRKESLQLHNVTKAEKPARVSKDVEDVPASKKAKEGTED 676
Score = 27.7 bits (60), Expect = 8.3
Identities = 20/72 (27%), Positives = 32/72 (44%), Gaps = 1/72 (1%)
Query: 96 PSGVAKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKG-KKEDVRKDKKIADADLS 154
P G ++ K K E+ KEK + +E K RK+ + +V K +K A
Sbjct: 601 PKGTSEVTESGKKKTEISEKESKEKADMKHLREEKVSTRKESLQLHNVTKAEKPARVSKD 660
Query: 155 RKESPKGKKDRE 166
++ P KK +E
Sbjct: 661 VEDVPASKKAKE 672
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 61.2 bits (147), Expect = 7e-10
Identities = 33/112 (29%), Positives = 61/112 (54%), Gaps = 1/112 (0%)
Query: 101 KRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPK 160
K K K K +E KE +K KE+ + RKE + +ER+K KKE ++++K +K+ +
Sbjct: 61 KEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKER 120
Query: 161 GKKDRE-KEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSSTR 211
+++RE K++ + ++ + K+ R+K + K + K +KE R R
Sbjct: 121 KERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKR 172
Score = 56.2 bits (134), Expect = 2e-08
Identities = 31/107 (28%), Positives = 56/107 (52%), Gaps = 5/107 (4%)
Query: 101 KRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPK 160
K K K + K+ + E KK+KE+ E +E+K +K KK +K +K ++E +
Sbjct: 99 KEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRK-----ERKREKER 153
Query: 161 GKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESR 207
GK++R+++K E+ K +E +K + + R K+ +KE R
Sbjct: 154 GKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERR 200
Score = 55.5 bits (132), Expect = 4e-08
Identities = 32/113 (28%), Positives = 62/113 (54%), Gaps = 2/113 (1%)
Query: 101 KRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVR-KDKKIADADLSRKES- 158
+R+++ K + +E+ K+E+EK R+ K E++K+ K+E + +++K + + RKE
Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
Query: 159 PKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSSTR 211
K ++ R+KEK E+ + + RKK K+ + R + RK+ R R
Sbjct: 91 EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKR 143
Score = 55.5 bits (132), Expect = 4e-08
Identities = 29/124 (23%), Positives = 61/124 (49%)
Query: 101 KRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPK 160
K + + + K+ K+ K+E+ K RK + E+++K ++E R+ +K RK+ +
Sbjct: 52 KERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGR 111
Query: 161 GKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSSTRYAHLTKGNT 220
++ ++KE+ + E+ K + RK+ K K R+K+ K R + +
Sbjct: 112 RERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKK 171
Query: 221 QKRN 224
++RN
Sbjct: 172 RERN 175
Score = 55.1 bits (131), Expect = 5e-08
Identities = 30/126 (23%), Positives = 65/126 (51%), Gaps = 2/126 (1%)
Query: 100 AKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESP 159
++RK + + +E K E +KE+++ +KE K ++++ KE RK K+ R+E
Sbjct: 34 SERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKE 93
Query: 160 KGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKM--ASRDKDDRKESRSSTRYAHLTK 217
+ K+ +EK+K + ++ + + +KK ++ +K + K RK+ R R +
Sbjct: 94 RRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKER 153
Query: 218 GNTQKR 223
G +++
Sbjct: 154 GKRERK 159
Score = 53.5 bits (127), Expect = 1e-07
Identities = 36/127 (28%), Positives = 67/127 (52%), Gaps = 5/127 (3%)
Query: 101 KRKTKAKVKELTKEELKKEKEKPESRKESKNEERK-KGKKE-DVRKDKKIADADLSRKES 158
+R+ K K +E ++E ++EKE+ + +KE K ERK +G++E +K++K + + ++
Sbjct: 74 ERERKRKEREKQRKE-RREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRE 132
Query: 159 PKGKKDREKEKVDLEKSAKT--KENRKKSTNMKDVSSKMASRDKDDRKESRSSTRYAHLT 216
K KK R+K++ K K K RK+ K+ K R++ +RK+ R
Sbjct: 133 RKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERK 192
Query: 217 KGNTQKR 223
K ++R
Sbjct: 193 KERKKER 199
Score = 51.2 bits (121), Expect = 7e-07
Identities = 25/111 (22%), Positives = 54/111 (48%)
Query: 113 KEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPKGKKDREKEKVDL 172
+ E KKE+ + E RK + +ERK+ + + +K +K + R+ K ++ + KE+ +
Sbjct: 33 ESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREK 92
Query: 173 EKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSSTRYAHLTKGNTQKR 223
E+ + KE +K+ + + +++ +R+ R K +KR
Sbjct: 93 ERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKR 143
Score = 50.4 bits (119), Expect = 1e-06
Identities = 31/99 (31%), Positives = 53/99 (53%), Gaps = 6/99 (6%)
Query: 98 GVAKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKK-----GKKEDVRKDKKIADAD 152
G +RK K + KE +E ++ + K + R++ K + +K GK+E RK +K + +
Sbjct: 110 GRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEERE 169
Query: 153 LSRKESPK-GKKDREKEKVDLEKSAKTKENRKKSTNMKD 190
R+ + K KK+RE+++ K + KE RKK KD
Sbjct: 170 KKRERNRKERKKERERKERRERKKERKKERRKKKERKKD 208
Score = 49.7 bits (117), Expect = 2e-06
Identities = 27/110 (24%), Positives = 56/110 (50%), Gaps = 7/110 (6%)
Query: 102 RKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPKG 161
R+ + K KE + E + ++ + RK+ + ++R+K +K + + K+ RK +
Sbjct: 111 RRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKR------ERKRKKRK 164
Query: 162 KKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSSTR 211
K++REK++ + + + KE +K + K R K +RK+ R + R
Sbjct: 165 KEEREKKR-ERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDR 213
Score = 48.5 bits (114), Expect = 5e-06
Identities = 33/86 (38%), Positives = 54/86 (62%), Gaps = 10/86 (11%)
Query: 101 KRKTKAKVKELTKEELKKEKEKPE---SRKESKNEERKKGKKEDVRKDKKIADADLSRKE 157
+RK K + K+ ++E K+EKE+ + RK+ K EER+K K+E RK++K + RKE
Sbjct: 132 ERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREK-KRERNRKERK---KERERKE 187
Query: 158 SPKGKKDREKEKVDLEKSAKTKENRK 183
+ KK+R+KE+ K + K++RK
Sbjct: 188 RRERKKERKKER---RKKKERKKDRK 210
Score = 47.0 bits (110), Expect = 1e-05
Identities = 29/132 (21%), Positives = 62/132 (46%), Gaps = 1/132 (0%)
Query: 92 LLEGPSGVAKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADA 151
+++ S A K +++ ++ + K + ES ++ + ER+K K+E K++K
Sbjct: 1 MVKAISSRAAVKLNTELQMVSCSHISKPCTQRESERKKERREREKRKRER-EKERKRERG 59
Query: 152 DLSRKESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSSTR 211
+K+ K ++ +E+E+ E+ + KE R+K + K R + R+E +
Sbjct: 60 KKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKE 119
Query: 212 YAHLTKGNTQKR 223
+ N Q+R
Sbjct: 120 RKERERENKQRR 131
Score = 39.3 bits (90), Expect = 0.003
Identities = 21/58 (36%), Positives = 35/58 (60%), Gaps = 3/58 (5%)
Query: 101 KRKTKAKVKELTKEELKKEKEKPESR---KESKNEERKKGKKEDVRKDKKIADADLSR 155
K++ + K +E ++E KKE+E+ E R KE K E RKK +++ RK + D+ + R
Sbjct: 164 KKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFR 221
Score = 34.7 bits (78), Expect = 0.068
Identities = 18/56 (32%), Positives = 33/56 (58%), Gaps = 1/56 (1%)
Query: 101 KRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRK 156
++K K + +E +E +KE++K RKE + E +K+ KKE +K ++ D R+
Sbjct: 160 RKKRKKEEREKKRERNRKERKKERERKE-RRERKKERKKERRKKKERKKDRKTDRQ 214
Score = 28.9 bits (63), Expect = 3.7
Identities = 14/55 (25%), Positives = 32/55 (58%), Gaps = 1/55 (1%)
Query: 102 RKTKAKVKELT-KEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSR 155
RK + K +E + E KKE++K +K+ + ++RK ++ D + + + ++ +R
Sbjct: 176 RKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFNR 230
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 60.8 bits (146), Expect = 9e-10
Identities = 41/111 (36%), Positives = 63/111 (56%), Gaps = 4/111 (3%)
Query: 101 KRKTKAKVKELTKEELKKE-KEKPESRKESKNEERKK-GKKEDVRKDKKIADADLSRKES 158
+RK + K +E + E KKE +EK RKE K ERK+ G+KE+ RK+K+ + +
Sbjct: 134 ERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNR 193
Query: 159 PKGKKDRE-KEKVDLEKSAKTKENRKKSTNM-KDVSSKMASRDKDDRKESR 207
+ KK+RE KE+ + +K K KE RKK + + + R K +RKE +
Sbjct: 194 KERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERK 244
Score = 59.7 bits (143), Expect = 2e-09
Identities = 33/111 (29%), Positives = 58/111 (52%), Gaps = 2/111 (1%)
Query: 101 KRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPK 160
K++ K + K+ +E K+ +EK E K + +KK KKE R K+ + + + +
Sbjct: 83 KKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKRE 142
Query: 161 GKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSSTR 211
+K+RE++K + EK + KE +K+ K V K R + +RKE + R
Sbjct: 143 ERKERERKKEEREKERERKERKKR--ERKQVGEKEEERKEKERKERKKRER 191
Score = 59.3 bits (142), Expect = 3e-09
Identities = 34/114 (29%), Positives = 64/114 (56%), Gaps = 7/114 (6%)
Query: 101 KRKTKAKVKELTKEELKKEKEKPE---SRKESKNEERKKGKKEDVRKDKKIADADLSRKE 157
KR+ + + KE ++E +K+KEK E + KE K ERK+ +K + RK+++ + ++
Sbjct: 99 KRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKER 158
Query: 158 SPKGKKDREK----EKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESR 207
K +K RE+ EK + K + KE +K+ N K+ + +++ +RK+ R
Sbjct: 159 ERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKER 212
Score = 55.1 bits (131), Expect = 5e-08
Identities = 29/110 (26%), Positives = 61/110 (55%), Gaps = 2/110 (1%)
Query: 98 GVAKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKE 157
G +R+++ K + +E+ K+E+EK R+ K E KKG+++ +++K + KE
Sbjct: 51 GKKERESERKKERREREKRKREREKERKRERGKKE--KKGERKKEERERKKRRREKENKE 108
Query: 158 SPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESR 207
+ +K ++KEK + +++K + R++ K K R K++R++ R
Sbjct: 109 GEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKER 158
Score = 55.1 bits (131), Expect = 5e-08
Identities = 26/107 (24%), Positives = 61/107 (57%), Gaps = 2/107 (1%)
Query: 101 KRKTKAKVKELTKEELKKEKEKPESRKESKNE--ERKKGKKEDVRKDKKIADADLSRKES 158
+++ + K +E KEE +KE+E+ E +K + + E+++ +KE RK++K + + ++
Sbjct: 139 RKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKK 198
Query: 159 PKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKE 205
+ +K+R + K + +K + K+ R+K + R++ +RK+
Sbjct: 199 ERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 54.7 bits (130), Expect = 6e-08
Identities = 35/126 (27%), Positives = 63/126 (50%), Gaps = 3/126 (2%)
Query: 101 KRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPK 160
K K + E KE ++EK K E KE K E KK KK + +K+++ KE+ +
Sbjct: 49 KEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKE 108
Query: 161 GK-KDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSSTRYAHLTKGN 219
G+ K++ K+K E+ +KE +++ K+ + ++++ +KE R R K
Sbjct: 109 GEEKEKRKKKEKKERGRTSKEGKERER--KEERKREERKERERKKEEREKERERKERKKR 166
Query: 220 TQKRNG 225
+K+ G
Sbjct: 167 ERKQVG 172
Score = 54.7 bits (130), Expect = 6e-08
Identities = 34/130 (26%), Positives = 67/130 (51%), Gaps = 9/130 (6%)
Query: 101 KRKTKAKVKELTKEELKKEKEKPESR-------KESKNEERKKGKKEDVRKDKKIADADL 153
+RK + + KE KE +KEK K + + KE K ERK+ +K + RK+++ +
Sbjct: 96 ERKKRRREKE-NKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEER 154
Query: 154 SRKESPKGKKDREKEKV-DLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSSTRY 212
++ K +K RE+++V + E+ K KE +++ ++ + R++ +R+E + +
Sbjct: 155 EKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKK 214
Query: 213 AHLTKGNTQK 222
K QK
Sbjct: 215 KEERKKERQK 224
Score = 54.7 bits (130), Expect = 6e-08
Identities = 35/117 (29%), Positives = 59/117 (50%), Gaps = 6/117 (5%)
Query: 101 KRKTKAKVKELTKEELKKEKEKPESRK--ESKNEERKKGKKEDVRKD---KKIADADLSR 155
++K + + + KE +KE+ K E RK E K EER+K ++ RK K++ + + R
Sbjct: 119 EKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEER 178
Query: 156 KESP-KGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSSTR 211
KE K +K RE+ + + +K + KE R++ K + R KD + R R
Sbjct: 179 KEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKER 235
Score = 53.5 bits (127), Expect = 1e-07
Identities = 30/131 (22%), Positives = 65/131 (49%), Gaps = 1/131 (0%)
Query: 94 EGPSGVAKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADL 153
EG ++K + K + T +E K+ + K E ++E + E +K ++ + +++K
Sbjct: 108 EGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRE 167
Query: 154 SRKESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASR-DKDDRKESRSSTRY 212
++ K ++ +EKE+ + +K + ++ RKK K+ + R K++RK+ R R
Sbjct: 168 RKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQ 227
Query: 213 AHLTKGNTQKR 223
+ + KR
Sbjct: 228 TNWREKERGKR 238
Score = 49.3 bits (116), Expect = 3e-06
Identities = 27/111 (24%), Positives = 57/111 (51%), Gaps = 2/111 (1%)
Query: 97 SGVAKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRK 156
S + +R+ + + ++ K+E +E E+ + R+E + +R++ K+ + KK + ++
Sbjct: 36 SEIREREREIETRKEGKKE--RESERKKERREREKRKREREKERKRERGKKEKKGERKKE 93
Query: 157 ESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESR 207
E + K+ REKE + E+ K K+ KK K R ++ ++E R
Sbjct: 94 ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREER 144
Score = 46.6 bits (109), Expect = 2e-05
Identities = 30/118 (25%), Positives = 58/118 (49%), Gaps = 8/118 (6%)
Query: 113 KEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPKGKKD----REKE 168
+ E+++ + + E+RKE K E + KKE ++K+ + + RK +GKK+ R+KE
Sbjct: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRE-RGKKEKKGERKKE 93
Query: 169 KVDLEKSAKTKENRK---KSTNMKDVSSKMASRDKDDRKESRSSTRYAHLTKGNTQKR 223
+ + +K + KEN++ K K + K+ ++ R R K +K+
Sbjct: 94 ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKK 151
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 60.8 bits (146), Expect = 9e-10
Identities = 42/135 (31%), Positives = 68/135 (50%), Gaps = 5/135 (3%)
Query: 80 GDGDFDVDDAKVLLEGPSGVAKRKTKAKVKELTKEELKKEKEKPESRKESKNEER--KKG 137
GD +D++ L + K+K K+ T E E E ES+K+ K +++ K
Sbjct: 375 GDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSE--SELESKESQKDEKKDKKDSKTD 432
Query: 138 KKEDVRKDKKIADADLSRK-ESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMA 196
K+ V+ D++ DAD K +S KGKKD +K K D +K K K+ +K + + + S
Sbjct: 433 NKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLEL 492
Query: 197 SRDKDDRKESRSSTR 211
+DK KE + S +
Sbjct: 493 KKDKKHSKEKKGSKK 507
Score = 55.1 bits (131), Expect = 5e-08
Identities = 36/122 (29%), Positives = 64/122 (52%), Gaps = 14/122 (11%)
Query: 101 KRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPK 160
K+ TK K+ + E + K+ + K+ K +K KK+DV+KD + DA+ +S
Sbjct: 285 KKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESG--DSKD 342
Query: 161 GKKDREKEKVDLEKSAKTKENRK-------KSTNMKDVSS-----KMASRDKDDRKESRS 208
+KD +K+K L+K K K+ +K +S + KD + K AS++ D +K+++
Sbjct: 343 ERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKK 402
Query: 209 ST 210
T
Sbjct: 403 IT 404
Score = 50.8 bits (120), Expect = 9e-07
Identities = 44/137 (32%), Positives = 70/137 (51%), Gaps = 21/137 (15%)
Query: 95 GPSGVAKRKTKAKVKELTKEELKKEKEK-PES-----------RKESKNEERKKGKKEDV 142
G S ++ TK K+L K++ KK+ +K PES R +S+N +K K +D
Sbjct: 338 GDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRN-LKKASKNDDK 396
Query: 143 RKD-KKI-----ADADLSRKESPKG-KKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKM 195
+KD KKI ++++L KES K KKD++ K D +KS K E + + SK
Sbjct: 397 KKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKK 456
Query: 196 ASRD-KDDRKESRSSTR 211
+D K +K+S+ +
Sbjct: 457 GKKDEKKGKKDSKKDDK 473
Score = 50.4 bits (119), Expect = 1e-06
Identities = 38/126 (30%), Positives = 61/126 (48%), Gaps = 10/126 (7%)
Query: 84 FDVDDAKVLLEGPSGVAKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVR 143
F D L S ++K K K K+ +K ++E ++ E K + KKGKK D +
Sbjct: 405 FSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDS-KKGKK-DEK 462
Query: 144 KDKKIADADLSRKESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDR 203
K KK + D +K++ K + E E DLE K +++K + KD+ KD R
Sbjct: 463 KGKKDSKKDDKKKDAKKNAESTEMES-DLELKKDKKHSKEKKGSKKDIK-------KDAR 514
Query: 204 KESRSS 209
K++ S+
Sbjct: 515 KDTEST 520
Score = 48.5 bits (114), Expect = 5e-06
Identities = 34/114 (29%), Positives = 54/114 (47%), Gaps = 3/114 (2%)
Query: 111 LTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRK-ESPKGKKDREKEK 169
L K E KK K++ K+ ++K G + K+I + R+ E+ K E
Sbjct: 110 LKKAEYKKSKDEKGGTPLKKDSKKKGGSYATNPESKQIVEEKTKRQNEADKTPLKSSHEN 169
Query: 170 VDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKES-RSSTRYAHLTKGNTQK 222
+KS + E +S N K VS + +DK D K S +++T + H TK N +K
Sbjct: 170 EQSKKSKSSSETNPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLH-TKNNPKK 222
Score = 43.1 bits (100), Expect = 2e-04
Identities = 40/189 (21%), Positives = 84/189 (44%), Gaps = 32/189 (16%)
Query: 49 VDYEEVLAKAKDFRYNLSEVLQGKLGIYDADGDGDFDVDDAKVLLEGPSGVAKRKTKAKV 108
VD+ ++ ++ D N L+ Y + ++ + K + AK+ + A+
Sbjct: 245 VDFLMLVGQSDDESINFDAWLRN----YSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAES 300
Query: 109 KELTKEELKKEKEKPESRKESKNEERK-------------KGKKEDVRKDKKIADADLSR 155
++ + +K K +K+ K ++ K K +++D +KDKK D +
Sbjct: 301 EDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKK 360
Query: 156 KESPK----------GKKDREKEKVDLEKSAKT---KENRKKSTNMKDVSSKMASRD--K 200
K++ K KD + +L+K++K K++ KK T D S++ S++ K
Sbjct: 361 KDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQK 420
Query: 201 DDRKESRSS 209
D++K+ + S
Sbjct: 421 DEKKDKKDS 429
Score = 41.2 bits (95), Expect = 7e-04
Identities = 24/95 (25%), Positives = 50/95 (52%), Gaps = 13/95 (13%)
Query: 117 KKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPKGKKDREKEKVDLEKSA 176
K +K++ + +K+SK +++KK K++ + ++DL K+ K K+++ K D++K A
Sbjct: 456 KGKKDEKKGKKDSKKDDKKKDAKKNAESTE--MESDLELKKDKKHSKEKKGSKKDIKKDA 513
Query: 177 KTKENRKKSTNMKDVSSKMASRDKDDRKESRSSTR 211
+ KD S A D+ + ++ST+
Sbjct: 514 R-----------KDTESTDAEFDESSKTGFKTSTK 537
Score = 39.7 bits (91), Expect = 0.002
Identities = 29/89 (32%), Positives = 47/89 (52%), Gaps = 7/89 (7%)
Query: 125 SRKESKNEERKKGK--KEDVRKDKKIADADLSRKESPKGKKDREKEKVDLEKSAKTKENR 182
S+ SKN K K K+D +K+ K +D ++S KKD +K K +++K K K++
Sbjct: 269 SQNNSKNYSLKYTKYTKKDTKKNAK-KSSDAESEDSKDAKKDSKKVKKNVKKDDK-KKDV 326
Query: 183 KKSTNMKDVSSKMASRDKDDRKESRSSTR 211
KK T D S KD+RK+++ +
Sbjct: 327 KKDTESTDAES---GDSKDERKDTKKDKK 352
Score = 38.9 bits (89), Expect = 0.004
Identities = 40/149 (26%), Positives = 64/149 (42%), Gaps = 22/149 (14%)
Query: 83 DFDVDDAKVLLEGPSGVAKRKTKAKVKELTKEELKKEKEKP----------ESRKESKNE 132
D + DA +G S K+ K K+ K++ KK+ +K E +K+ K+
Sbjct: 440 DEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKHS 499
Query: 133 ERKKGKKE----DVRKDKKIADADLSR------KESPKGK-KDREKEKVDLEKSAKTKEN 181
+ KKG K+ D RKD + DA+ K S K K D E E+ + AK K +
Sbjct: 500 KEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTKIKGSDTESEESLYKPGAKKKID 559
Query: 182 RKKSTNMKDVSSKMASRDKDDRKESRSST 210
T+ + S+ + R S+ +T
Sbjct: 560 ESDGTSANSKMEGLESK-RGFRMSSKKTT 587
Score = 38.1 bits (87), Expect = 0.006
Identities = 27/100 (27%), Positives = 42/100 (42%), Gaps = 2/100 (2%)
Query: 94 EGPSGVAKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADL 153
+G S ++K V+E TK + E +K + +NE+ KK K + +
Sbjct: 134 KGGSYATNPESKQIVEEKTKRQ--NEADKTPLKSSHENEQSKKSKSSSETNPESQNSKTV 191
Query: 154 SRKESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSS 193
S+ S K KKD + K + TK N KK S+
Sbjct: 192 SKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSN 231
Score = 32.0 bits (71), Expect = 0.44
Identities = 33/125 (26%), Positives = 51/125 (40%), Gaps = 20/125 (16%)
Query: 114 EELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPKGKKDREKEKVDLE 173
E+ KK K E+ ES+N K K +KDKK D+ S+K + + + K DL+
Sbjct: 170 EQSKKSKSSSETNPESQNS--KTVSKNCSQKDKK--DSKNSKKTNTEFLHTKNNPKKDLK 225
Query: 174 KSAKTKENRKK--STNMKDVSSKMASRDKDD--------------RKESRSSTRYAHLTK 217
+S + + + S N +V M DD S +Y TK
Sbjct: 226 RSKTSNDPISEICSENSLNVDFLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKYTKYTK 285
Query: 218 GNTQK 222
+T+K
Sbjct: 286 KDTKK 290
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 58.5 bits (140), Expect = 4e-09
Identities = 32/116 (27%), Positives = 60/116 (51%), Gaps = 5/116 (4%)
Query: 101 KRKTKAKVKEL-----TKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSR 155
K+K K + +E T+EE +KE ++ E RKE + E+ KK K ++ K K+ + + R
Sbjct: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR 62
Query: 156 KESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSSTR 211
K K KK+ E+ + + E+ + KE +K + K R +++ ++ + R
Sbjct: 63 KRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRR 118
Score = 54.3 bits (129), Expect = 8e-08
Identities = 32/104 (30%), Positives = 56/104 (53%), Gaps = 8/104 (7%)
Query: 101 KRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPK 160
KRK K K K KE+ KK KE E RKE + EE+K+ +K +K+++ +E +
Sbjct: 28 KRKEKRKEKRKEKEKKKKTKE-TEKRKEKEEEEKKRKRKRKKKKEEE-------EREEEE 79
Query: 161 GKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRK 204
+++ EKE+ + E+ + K+ +K+ ++ K R K +K
Sbjct: 80 EEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123
Score = 51.2 bits (121), Expect = 7e-07
Identities = 31/113 (27%), Positives = 58/113 (51%), Gaps = 4/113 (3%)
Query: 103 KTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRK---ESP 159
K K K K+ T+E + E+ + E KE K +E++K K+++ K KK + + ++ E
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 160 KGKKDREKEKVDLEK-SAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSSTR 211
K K+ R+K+K + E+ + +E +K K+ + + K RKE +
Sbjct: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKK 113
Score = 48.1 bits (113), Expect = 6e-06
Identities = 28/104 (26%), Positives = 56/104 (53%), Gaps = 8/104 (7%)
Query: 109 KELTKEELKKEKEKP-ESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPKGKKDREK 167
KE ++E +KEK K E +K++K E++K K+E+ +K K+ +E + +++ E+
Sbjct: 25 KEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEE 84
Query: 168 EKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSSTR 211
EK + EK + +KK K+ +++ +K+ R T+
Sbjct: 85 EKEEEEKEEGRRRKKKKKRRRKE-------EEEEKKKKRRRKTK 121
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 57.4 bits (137), Expect = 1e-08
Identities = 38/134 (28%), Positives = 74/134 (55%), Gaps = 12/134 (8%)
Query: 101 KRKTKAKVKELTKEELK-KEKEKPESRKESKNEERKKGKKEDVRKDK-----KIADADLS 154
++ T+ K+KE KE +K K++EK R++ + +E+++GK +D K++ K + D
Sbjct: 377 RKDTREKIKE--KERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRE 434
Query: 155 RKESPKGKKDREKEK-VDLEKSAKTKENRKKSTN---MKDVSSKMASRDKDDRKESRSST 210
R+ + +KDR+KEK + +K + +++R K + KD S+ R + + SRSS+
Sbjct: 435 REREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSS 494
Query: 211 RYAHLTKGNTQKRN 224
R + + R+
Sbjct: 495 RERRRRRSRSSSRS 508
Score = 54.7 bits (130), Expect = 6e-08
Identities = 39/132 (29%), Positives = 69/132 (52%), Gaps = 16/132 (12%)
Query: 101 KRKTKAKVKELTKE-ELKKEKEKPESRKESKNEERKKGKKEDVRKDKKI----------- 148
K K K +VKE +E E ++EKE+ + ++ KN++R K +++D KDK+
Sbjct: 383 KIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHE 442
Query: 149 ADADLSRKESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKD---DRKE 205
D D +++ +K+REK++ E K K+++K T + ++ SR R+
Sbjct: 443 KDRDKEKEKEQDKEKEREKDR-SKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRR 501
Query: 206 SRSSTRYAHLTK 217
SRSS+R +K
Sbjct: 502 SRSSSRSPRTSK 513
Score = 44.7 bits (104), Expect = 7e-05
Identities = 26/115 (22%), Positives = 57/115 (49%), Gaps = 4/115 (3%)
Query: 100 AKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESP 159
+K ++++ + ++++ ++ + P +K SK+ ER+K + +DK+ + +++
Sbjct: 331 SKHRSRSHNRSRSRQKDRRRSKSPH-KKRSKSRERRKSRSRSHSRDKRKDTREKIKEKER 389
Query: 160 KGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSSTRYAH 214
+KDREKE+ ++ K KE K K+ + R+KD K+ H
Sbjct: 390 VKEKDREKEREREKEREKEKERGKNKDRDKE---REKDREKDKEKDREREREKEH 441
Score = 44.3 bits (103), Expect = 9e-05
Identities = 26/111 (23%), Positives = 59/111 (53%), Gaps = 8/111 (7%)
Query: 100 AKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESP 159
+++K + + K K+ K +E+ +SR S + +++K +E +++ +++ + D R++
Sbjct: 343 SRQKDRRRSKSPHKKR-SKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKD--REKER 399
Query: 160 KGKKDREKEK-----VDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKE 205
+ +K+REKEK D +K + + K + + K +D+D KE
Sbjct: 400 EREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKE 450
Score = 40.4 bits (93), Expect = 0.001
Identities = 25/105 (23%), Positives = 46/105 (43%), Gaps = 9/105 (8%)
Query: 119 EKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPKGKKDREKEKVDLEKSAKT 178
E++ SR ++++ R K RK + S S +KDR + K +K +K+
Sbjct: 302 ERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKS 361
Query: 179 KENRKKSTNMKDVSSKMASRDKDDRKESRSSTRYAHLTKGNTQKR 223
+E RK S+ S +D RK++R + K +++
Sbjct: 362 RERRK---------SRSRSHSRDKRKDTREKIKEKERVKEKDREK 397
Score = 40.4 bits (93), Expect = 0.001
Identities = 31/134 (23%), Positives = 60/134 (44%), Gaps = 10/134 (7%)
Query: 100 AKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDK-KIADADLSRKES 158
+K ++ +K K K + + +R S+ ++R++ K ++ K + SR S
Sbjct: 314 SKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHS 373
Query: 159 PKGKKD-----REKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKD---DRKESRSST 210
+KD +EKE+V EK + + R+K + K RDK+ DR++ +
Sbjct: 374 RDKRKDTREKIKEKERVK-EKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKD 432
Query: 211 RYAHLTKGNTQKRN 224
R K + + R+
Sbjct: 433 REREREKEHEKDRD 446
Score = 40.0 bits (92), Expect = 0.002
Identities = 28/135 (20%), Positives = 59/135 (43%), Gaps = 13/135 (9%)
Query: 101 KRKTKAKVKELTKE-------ELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADL 153
K K K + +E KE E +KE++K + R++ +++E + +K+D + +
Sbjct: 427 KDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNA 486
Query: 154 SRKESPKGKKDREKEKVDLEKSAKT------KENRKKSTNMKDVSSKMASRDKDDRKESR 207
SR+ ++ R + +S +T K +R S ++ K +++D E R
Sbjct: 487 SRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERR 546
Query: 208 SSTRYAHLTKGNTQK 222
R + K + +
Sbjct: 547 ERERSTSMRKSSNDR 561
Score = 37.0 bits (84), Expect = 0.014
Identities = 27/132 (20%), Positives = 59/132 (44%), Gaps = 16/132 (12%)
Query: 94 EGPSGVAKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADL 153
E G ++ T++K + +K +++ R +SK+ R + +KD++
Sbjct: 302 ERKGGRSRSHTRSKSRSSSKSHSRRK------RSQSKHRSRSHNRSRSRQKDRR------ 349
Query: 154 SRKESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKE-SRSSTRY 212
R +SP K+ + +E+ + +++ RK + + + K ++KD KE R R
Sbjct: 350 -RSKSPHKKRSKSRERRKSRSRSHSRDKRKDT--REKIKEKERVKEKDREKEREREKERE 406
Query: 213 AHLTKGNTQKRN 224
+G + R+
Sbjct: 407 KEKERGKNKDRD 418
Score = 37.0 bits (84), Expect = 0.014
Identities = 26/120 (21%), Positives = 54/120 (45%), Gaps = 13/120 (10%)
Query: 101 KRKTKAKVKELTKEELKKEKEKPESR--------KESKNEERKKGKKEDVRKDK--KIAD 150
K + K + KE+ ++ K +K + R + S E R++ + R + K
Sbjct: 457 KEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIK 516
Query: 151 ADLSRKESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSST 210
SR SP+ + ++K++ + R++ST+M+ S+ RD ++ E S++
Sbjct: 517 RKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSN---DRDGKEKLEKNSTS 573
Score = 31.6 bits (70), Expect = 0.57
Identities = 29/137 (21%), Positives = 60/137 (43%), Gaps = 25/137 (18%)
Query: 100 AKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESP 159
A R++++ +E + + P + SK +RK + R SR +
Sbjct: 486 ASRRSRSSSRERRRRRSRSSSRSPRT---SKTIKRKSSRSPSPR----------SRNKKD 532
Query: 160 KGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKM-----ASRDKDDRKESRSST---- 210
K K+++E++ + + + + +KS+N +D K+ + ++K+ KE SS
Sbjct: 533 K-KREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEV 591
Query: 211 --RYAHLTKGNTQKRNG 225
+ A T+ N + NG
Sbjct: 592 DDKDAPRTEENKIQHNG 608
Score = 30.0 bits (66), Expect = 1.7
Identities = 25/107 (23%), Positives = 47/107 (43%), Gaps = 15/107 (14%)
Query: 97 SGVAKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRK 156
S KRK+ ++ + K++EK ++ +E R++ + +RK D
Sbjct: 512 SKTIKRKSSRSPSPRSRNKKDKKREK---ERDHISERRERERSTSMRKSSNDRD------ 562
Query: 157 ESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDR 203
GK+ EK L++ KE S+ K+V K A R ++++
Sbjct: 563 ----GKEKLEKNSTSLKEKEHNKE--PDSSVSKEVDDKDAPRTEENK 603
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 57.4 bits (137), Expect = 1e-08
Identities = 38/134 (28%), Positives = 74/134 (55%), Gaps = 12/134 (8%)
Query: 101 KRKTKAKVKELTKEELK-KEKEKPESRKESKNEERKKGKKEDVRKDK-----KIADADLS 154
++ T+ K+KE KE +K K++EK R++ + +E+++GK +D K++ K + D
Sbjct: 261 RKDTREKIKE--KERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRE 318
Query: 155 RKESPKGKKDREKEK-VDLEKSAKTKENRKKSTN---MKDVSSKMASRDKDDRKESRSST 210
R+ + +KDR+KEK + +K + +++R K + KD S+ R + + SRSS+
Sbjct: 319 REREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSS 378
Query: 211 RYAHLTKGNTQKRN 224
R + + R+
Sbjct: 379 RERRRRRSRSSSRS 392
Score = 54.7 bits (130), Expect = 6e-08
Identities = 39/132 (29%), Positives = 69/132 (52%), Gaps = 16/132 (12%)
Query: 101 KRKTKAKVKELTKE-ELKKEKEKPESRKESKNEERKKGKKEDVRKDKKI----------- 148
K K K +VKE +E E ++EKE+ + ++ KN++R K +++D KDK+
Sbjct: 267 KIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHE 326
Query: 149 ADADLSRKESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKD---DRKE 205
D D +++ +K+REK++ E K K+++K T + ++ SR R+
Sbjct: 327 KDRDKEKEKEQDKEKEREKDR-SKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRR 385
Query: 206 SRSSTRYAHLTK 217
SRSS+R +K
Sbjct: 386 SRSSSRSPRTSK 397
Score = 44.7 bits (104), Expect = 7e-05
Identities = 26/115 (22%), Positives = 57/115 (49%), Gaps = 4/115 (3%)
Query: 100 AKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESP 159
+K ++++ + ++++ ++ + P +K SK+ ER+K + +DK+ + +++
Sbjct: 215 SKHRSRSHNRSRSRQKDRRRSKSPH-KKRSKSRERRKSRSRSHSRDKRKDTREKIKEKER 273
Query: 160 KGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSSTRYAH 214
+KDREKE+ ++ K KE K K+ + R+KD K+ H
Sbjct: 274 VKEKDREKEREREKEREKEKERGKNKDRDKE---REKDREKDKEKDREREREKEH 325
Score = 44.3 bits (103), Expect = 9e-05
Identities = 26/111 (23%), Positives = 59/111 (53%), Gaps = 8/111 (7%)
Query: 100 AKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESP 159
+++K + + K K+ K +E+ +SR S + +++K +E +++ +++ + D R++
Sbjct: 227 SRQKDRRRSKSPHKKR-SKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKD--REKER 283
Query: 160 KGKKDREKEK-----VDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKE 205
+ +K+REKEK D +K + + K + + K +D+D KE
Sbjct: 284 EREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKE 334
Score = 40.4 bits (93), Expect = 0.001
Identities = 25/105 (23%), Positives = 46/105 (43%), Gaps = 9/105 (8%)
Query: 119 EKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPKGKKDREKEKVDLEKSAKT 178
E++ SR ++++ R K RK + S S +KDR + K +K +K+
Sbjct: 186 ERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKS 245
Query: 179 KENRKKSTNMKDVSSKMASRDKDDRKESRSSTRYAHLTKGNTQKR 223
+E RK S+ S +D RK++R + K +++
Sbjct: 246 RERRK---------SRSRSHSRDKRKDTREKIKEKERVKEKDREK 281
Score = 40.4 bits (93), Expect = 0.001
Identities = 31/134 (23%), Positives = 60/134 (44%), Gaps = 10/134 (7%)
Query: 100 AKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDK-KIADADLSRKES 158
+K ++ +K K K + + +R S+ ++R++ K ++ K + SR S
Sbjct: 198 SKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHS 257
Query: 159 PKGKKD-----REKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKD---DRKESRSST 210
+KD +EKE+V EK + + R+K + K RDK+ DR++ +
Sbjct: 258 RDKRKDTREKIKEKERVK-EKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKD 316
Query: 211 RYAHLTKGNTQKRN 224
R K + + R+
Sbjct: 317 REREREKEHEKDRD 330
Score = 40.0 bits (92), Expect = 0.002
Identities = 28/135 (20%), Positives = 59/135 (43%), Gaps = 13/135 (9%)
Query: 101 KRKTKAKVKELTKE-------ELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADL 153
K K K + +E KE E +KE++K + R++ +++E + +K+D + +
Sbjct: 311 KDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNA 370
Query: 154 SRKESPKGKKDREKEKVDLEKSAKT------KENRKKSTNMKDVSSKMASRDKDDRKESR 207
SR+ ++ R + +S +T K +R S ++ K +++D E R
Sbjct: 371 SRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERR 430
Query: 208 SSTRYAHLTKGNTQK 222
R + K + +
Sbjct: 431 ERERSTSMRKSSNDR 445
Score = 37.0 bits (84), Expect = 0.014
Identities = 27/132 (20%), Positives = 59/132 (44%), Gaps = 16/132 (12%)
Query: 94 EGPSGVAKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADL 153
E G ++ T++K + +K +++ R +SK+ R + +KD++
Sbjct: 186 ERKGGRSRSHTRSKSRSSSKSHSRRK------RSQSKHRSRSHNRSRSRQKDRR------ 233
Query: 154 SRKESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKE-SRSSTRY 212
R +SP K+ + +E+ + +++ RK + + + K ++KD KE R R
Sbjct: 234 -RSKSPHKKRSKSRERRKSRSRSHSRDKRKDT--REKIKEKERVKEKDREKEREREKERE 290
Query: 213 AHLTKGNTQKRN 224
+G + R+
Sbjct: 291 KEKERGKNKDRD 302
Score = 37.0 bits (84), Expect = 0.014
Identities = 26/120 (21%), Positives = 54/120 (45%), Gaps = 13/120 (10%)
Query: 101 KRKTKAKVKELTKEELKKEKEKPESR--------KESKNEERKKGKKEDVRKDK--KIAD 150
K + K + KE+ ++ K +K + R + S E R++ + R + K
Sbjct: 341 KEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIK 400
Query: 151 ADLSRKESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSST 210
SR SP+ + ++K++ + R++ST+M+ S+ RD ++ E S++
Sbjct: 401 RKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSN---DRDGKEKLEKNSTS 457
Score = 31.6 bits (70), Expect = 0.57
Identities = 29/137 (21%), Positives = 60/137 (43%), Gaps = 25/137 (18%)
Query: 100 AKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESP 159
A R++++ +E + + P + SK +RK + R SR +
Sbjct: 370 ASRRSRSSSRERRRRRSRSSSRSPRT---SKTIKRKSSRSPSPR----------SRNKKD 416
Query: 160 KGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKM-----ASRDKDDRKESRSST---- 210
K K+++E++ + + + + +KS+N +D K+ + ++K+ KE SS
Sbjct: 417 K-KREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEV 475
Query: 211 --RYAHLTKGNTQKRNG 225
+ A T+ N + NG
Sbjct: 476 DDKDAPRTEENKIQHNG 492
Score = 30.0 bits (66), Expect = 1.7
Identities = 25/107 (23%), Positives = 47/107 (43%), Gaps = 15/107 (14%)
Query: 97 SGVAKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRK 156
S KRK+ ++ + K++EK ++ +E R++ + +RK D
Sbjct: 396 SKTIKRKSSRSPSPRSRNKKDKKREK---ERDHISERRERERSTSMRKSSNDRD------ 446
Query: 157 ESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDR 203
GK+ EK L++ KE S+ K+V K A R ++++
Sbjct: 447 ----GKEKLEKNSTSLKEKEHNKE--PDSSVSKEVDDKDAPRTEENK 487
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 53.9 bits (128), Expect = 1e-07
Identities = 34/112 (30%), Positives = 61/112 (54%), Gaps = 6/112 (5%)
Query: 100 AKRKTKAKVKELTKEELKKEKEKPE---SRKESKN--EERKKGKKEDVRKDKKIADADLS 154
AK KT K ++ E+ K+EKEKP+ ++KE K ++ +K KKE+V+K+ K +
Sbjct: 633 AKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVK-KEIKKE 691
Query: 155 RKESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKES 206
K+ PK + +E +++K K +E ++ K+ ++ KD +K S
Sbjct: 692 EKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSS 743
Score = 52.8 bits (125), Expect = 2e-07
Identities = 44/123 (35%), Positives = 63/123 (51%), Gaps = 10/123 (8%)
Query: 87 DDAKVLLEGPSG-VAKRKTKAKVKELTK---EELKKEKEKPESRKESKNEERKKGKKEDV 142
+D K E P VAK++ K +K+ K EE+KKE +K E +KE K E +K+ KKE
Sbjct: 647 EDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKK-EIKKEEKKEPKKEVKKETP 705
Query: 143 RKDKKIADADLSRKESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDD 202
K+ K +KE K +K+ +KE L K AK K ST + + A + K
Sbjct: 706 PKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAK-----KSSTPLSEAKKPAALKPKVP 760
Query: 203 RKE 205
+KE
Sbjct: 761 KKE 763
Score = 50.4 bits (119), Expect = 1e-06
Identities = 34/114 (29%), Positives = 62/114 (54%), Gaps = 10/114 (8%)
Query: 101 KRKTKAKVKELTKEELKKE-KEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESP 159
K+ T K K ++ +KKE K KPE +K EE++K KKE +K+ K + ++E P
Sbjct: 623 KQATDVKPKAAKEKTVKKETKVKPEDKK----EEKEKPKKEVAKKEDK---TPIKKEEKP 675
Query: 160 KGKKDREKEKVDLEKSAK--TKENRKKSTNMKDVSSKMASRDKDDRKESRSSTR 211
K ++ +++ K +++K K K+ KK T K+V ++ +K + K+ +
Sbjct: 676 KKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPK 729
Score = 45.8 bits (107), Expect = 3e-05
Identities = 28/86 (32%), Positives = 45/86 (52%)
Query: 101 KRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPK 160
K++ K + K+ K+E+KKE E +KE K EE+K+ KKE+ K+I K+S
Sbjct: 685 KKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSST 744
Query: 161 GKKDREKEKVDLEKSAKTKENRKKST 186
+ +K K K +E+ KK +
Sbjct: 745 PLSEAKKPAALKPKVPKKEESVKKDS 770
Score = 36.6 bits (83), Expect = 0.018
Identities = 29/116 (25%), Positives = 57/116 (49%), Gaps = 14/116 (12%)
Query: 103 KTKAKVKELTKEELKKEKEKPE----SRKESKNEERKKGKKEDVRKDKKIADADLSRKES 158
KT+ K KE KE+ P + K++ + + K K++ V+K+ K+ + E
Sbjct: 595 KTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKV------KPED 648
Query: 159 PKGKKDREKEKVDLEKS---AKTKENRKKSTNMKDVSSKMASRD-KDDRKESRSST 210
K +K++ K++V ++ K +E KK K+V ++ + K+ +KE + T
Sbjct: 649 KKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKET 704
Score = 35.4 bits (80), Expect = 0.040
Identities = 28/112 (25%), Positives = 47/112 (41%), Gaps = 12/112 (10%)
Query: 96 PSGVAKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSR 155
PS ++++K + E+TK EKP + + KK K + + ++
Sbjct: 553 PSKSVRKESKEETPEVTK---VNHVEKPPKVESKEKVMVKKDKPIKTETKPSVTEKEVPS 609
Query: 156 KESPKGKKDR--EKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKE 205
KE P K EK+ D++ A ++ KK T +K DK + KE
Sbjct: 610 KEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVK-------PEDKKEEKE 654
Score = 32.0 bits (71), Expect = 0.44
Identities = 25/78 (32%), Positives = 37/78 (47%), Gaps = 2/78 (2%)
Query: 118 KEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSR-KESPKGKKDREKEKVDLEKSA 176
K K++ +SR ES K + VRK+ K ++++ K K KEKV ++K
Sbjct: 534 KLKQRADSR-ESLKPAAKPLPSKSVRKESKEETPEVTKVNHVEKPPKVESKEKVMVKKDK 592
Query: 177 KTKENRKKSTNMKDVSSK 194
K K S K+V SK
Sbjct: 593 PIKTETKPSVTEKEVPSK 610
Score = 27.7 bits (60), Expect = 8.3
Identities = 31/130 (23%), Positives = 54/130 (41%), Gaps = 6/130 (4%)
Query: 91 VLLEGPSGVAKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIAD 150
V + P +A + K + +E K K+ K S ++ GK + + K A
Sbjct: 2217 VSMVDPEALAIEQNLGKALKKDLKEKTKTKKPGTKTKSSSPVKKSDGKSKPLAASPKPAG 2276
Query: 151 ADLSRKESPKGKKDREKEKVDLEKSAK---TKENRKKSTNMKDVSSKMASRDKDDRKESR 207
S + + ++KE V EK+AK T E + KD +K A+ + K ++
Sbjct: 2277 LKESSDKVSRVASPKKKESV--EKAAKPTTTPEVKAARGEEKDKETKNAA-NASASKSAK 2333
Query: 208 SSTRYAHLTK 217
++T TK
Sbjct: 2334 TATAGPGTTK 2343
>gi|4557509 cylicin 2 [Homo sapiens]
Length = 348
Score = 50.8 bits (120), Expect = 9e-07
Identities = 37/96 (38%), Positives = 50/96 (52%), Gaps = 7/96 (7%)
Query: 98 GVAKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKD-KKIADADLSRK 156
G + K KE+ K KK+K+KP S ++ KK K+D KD KK+A D + K
Sbjct: 254 GDESKDAKKDAKEIKKG--KKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKD-TEK 310
Query: 157 ESPKGKKDREKE-KVDLEKSAK--TKENRKKSTNMK 189
ES KKD +K K D +K AK K++ KK K
Sbjct: 311 ESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKK 346
Score = 48.5 bits (114), Expect = 5e-06
Identities = 44/144 (30%), Positives = 66/144 (45%), Gaps = 19/144 (13%)
Query: 87 DDAKVLLEGPSGVAKRKTKAKVKEL---TKEELKKEKEKPESRKES--KNEERKKGKKED 141
D L +G K K K KE K++ KK K+ E K+S ++E+ K G K+D
Sbjct: 129 DSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKD 188
Query: 142 VRKDKKIADADL------------SRKESPKGKKDREKEKVD-LEKSAKTKENRKKSTNM 188
+KDKK ++ + K+S KGKKD +K K +E A + +K
Sbjct: 189 NKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGK 248
Query: 189 KDVSSKMASRD-KDDRKESRSSTR 211
KD + S+D K D KE + +
Sbjct: 249 KDANKGDESKDAKKDAKEIKKGKK 272
Score = 47.4 bits (111), Expect = 1e-05
Identities = 38/130 (29%), Positives = 58/130 (44%), Gaps = 19/130 (14%)
Query: 93 LEGPSGVAKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADAD 152
+E S A+ K + K K+ E E + +K+SK KGK + K++K+
Sbjct: 105 VEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSK-----KGKDIEKGKEEKLD--- 156
Query: 153 LSRKESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSSTRY 212
++K+S KGKKD EK K +S K KK +DK D + + S
Sbjct: 157 -AKKDSKKGKKDAEKGKDSATESEDEKGGAKKDN----------KKDKKDSNKGKDSATE 205
Query: 213 AHLTKGNTQK 222
+ KG T+K
Sbjct: 206 SEGEKGGTEK 215
Score = 47.4 bits (111), Expect = 1e-05
Identities = 42/141 (29%), Positives = 66/141 (46%), Gaps = 11/141 (7%)
Query: 88 DAKVLLEGPSGVAKRKTKAKVKELTKEELKKEKEKPESRKE-SKNEERKKGKKEDVRKDK 146
D+K G G + KT K ++ ELK+ K+ + K+ K +E K K+D +K K
Sbjct: 108 DSKAAEIGKKG--EDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGK 165
Query: 147 KIAD-----ADLSRKESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKD 201
K A+ A S E KKD +K+K D S K K++ +S K + K + + K
Sbjct: 166 KDAEKGKDSATESEDEKGGAKKDNKKDKKD---SNKGKDSATESEGEKGGTEKDSKKGKK 222
Query: 202 DRKESRSSTRYAHLTKGNTQK 222
D K+ + S K + +K
Sbjct: 223 DSKKGKDSAIELQAVKADEKK 243
Score = 47.4 bits (111), Expect = 1e-05
Identities = 48/170 (28%), Positives = 78/170 (45%), Gaps = 19/170 (11%)
Query: 59 KDFRYNLSEVLQGKLGIYDADGDGDFDVDDAKVLLEGPSGVAKRKTKA------KVKELT 112
KD + + + +GK +++G+ D+K +G K K A K E
Sbjct: 187 KDNKKDKKDSNKGKDSATESEGEKGGTEKDSK---KGKKDSKKGKDSAIELQAVKADEKK 243
Query: 113 KEELKKEKEKPESRKESKNE--ERKKGKKEDVRKDKKIADADLSRKESPKGKKDREKEKV 170
E+ KK+ K + K++K + E KKGKK+ +K D+D + KKD K
Sbjct: 244 DEDGKKDANKGDESKDAKKDAKEIKKGKKD--KKKPSSTDSDSKDDVKKESKKDATK--- 298
Query: 171 DLEKSAKTKENRKKSTNMKDVSSKMASRD--KDDRKESRSSTRYAHLTKG 218
D +K AK K+ K+S + K + K A +D KD +K ++ + KG
Sbjct: 299 DAKKVAK-KDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKKG 347
Score = 41.2 bits (95), Expect = 7e-04
Identities = 48/193 (24%), Positives = 79/193 (40%), Gaps = 21/193 (10%)
Query: 47 DLVDYEEVLAKAKDFRYNLSEVLQGKLGIYDADGD---GDFDVD---DAKVLLEGPSGVA 100
D D E L + K ++ +GK DA D G D + D+ E G A
Sbjct: 126 DTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGA 185
Query: 101 KRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPK 160
K+ K K+ K K + E K ++ KKGKK+ KK D+ + +
Sbjct: 186 KKDNKKDKKDSNKG--KDSATESEGEKGGTEKDSKKGKKDS----KKGKDSAIELQAVKA 239
Query: 161 GKKDREKEKVDLEKSAKTKENRK--------KSTNMKDVSSKMASRDKDDRKESRSSTRY 212
+K E K D K ++K+ +K K K S+ S+D ++ + +T+
Sbjct: 240 DEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKD 299
Query: 213 A-HLTKGNTQKRN 224
A + K +T+K +
Sbjct: 300 AKKVAKKDTEKES 312
Score = 36.2 bits (82), Expect = 0.023
Identities = 28/107 (26%), Positives = 42/107 (39%), Gaps = 15/107 (14%)
Query: 57 KAKDFRYNLSEVLQGKLGIYDADGDGDFDVDDAKVLLEGPSGVAKRKTKAKVKELTKEEL 116
++KD + + E+ +GK DD K K K+ TK+
Sbjct: 256 ESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVK--------------KESKKDATKDAK 301
Query: 117 KKEKEKPESRKESKNEERKKGKKEDVRKD-KKIADADLSRKESPKGK 162
K K+ E ++ KK K+D +KD KK A D + KGK
Sbjct: 302 KVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKKGK 348
>gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]
Length = 237
Score = 50.8 bits (120), Expect = 9e-07
Identities = 36/138 (26%), Positives = 64/138 (46%), Gaps = 11/138 (7%)
Query: 90 KVLLEGPSGVAKRKTKAKVKELT---KEELKKEKEKPESRKESKNEERKKGKKEDVRKDK 146
K+L S KR+ K K K+ + + S +S++E++K+GK+ +K++
Sbjct: 69 KLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNR 128
Query: 147 KIADADLSRKESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSS--KMASRDKDDRK 204
++ S E+ KD L+K K+K+ +K ++K +S KM S DK
Sbjct: 129 SHKSSESSMSETESDSKD------SLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSS 182
Query: 205 ESRSSTRYAHLTKGNTQK 222
ES S + Y + +K
Sbjct: 183 ESLSESEYIEEVRAKKKK 200
Score = 50.4 bits (119), Expect = 1e-06
Identities = 37/120 (30%), Positives = 61/120 (50%), Gaps = 5/120 (4%)
Query: 107 KVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPKGKKDRE 166
K+ E K+EL+K +EK S ES +++R++ KKE +K + + + S +S D E
Sbjct: 54 KMNENWKKELEKHREKLLSGSESSSKKRQRKKKEK-KKSGRYSSSSSSSSDSSSSSSDSE 112
Query: 167 KEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDD---RKESRSSTRYAHLTKGNTQKR 223
E K K K+NR ++ + S+ S KD +K+S+ T KG ++KR
Sbjct: 113 DEDKKQGKRRKKKKNRSHKSSESSM-SETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKR 171
Score = 42.7 bits (99), Expect = 2e-04
Identities = 24/102 (23%), Positives = 54/102 (52%), Gaps = 1/102 (0%)
Query: 110 ELTKEELKKEKEKPESRKESKNEERKKGKKE-DVRKDKKIADADLSRKESPKGKKDREKE 168
E KE+L+K+K+ ++ E + + + KKE + ++K ++ ++ S K+ + KK+++K
Sbjct: 32 EEVKEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKKS 91
Query: 169 KVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSST 210
S+ + ++ S++ +D K R K + S S+
Sbjct: 92 GRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSS 133
Score = 40.4 bits (93), Expect = 0.001
Identities = 25/114 (21%), Positives = 52/114 (45%), Gaps = 1/114 (0%)
Query: 101 KRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGK-KEDVRKDKKIADADLSRKESP 159
K++ K + K+ + E E+ +SK+ +KK K K+ K+K I RK
Sbjct: 116 KKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYS 175
Query: 160 KGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSSTRYA 213
+ K + + E + + +KKS+ ++ +++ + K +K S+ + A
Sbjct: 176 EDKPLSSESLSESEYIEEVRAKKKKSSEEREKATEKTKKKKKHKKHSKKKKKKA 229
Score = 39.7 bits (91), Expect = 0.002
Identities = 35/152 (23%), Positives = 64/152 (42%), Gaps = 11/152 (7%)
Query: 57 KAKDFRYNLSEVLQGKLGIYDADG-DGDFDVDDAKVLLEGPSGVAKRKTKAKVKELTKEE 115
K K RY+ S +D D D + + S + + ++ + +K+
Sbjct: 88 KKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDS 147
Query: 116 LKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKE------SPKGKKDREKEK 169
LKK+K+ + ++ K+ + K++ +DK ++ LS E + K K E+EK
Sbjct: 148 LKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSEEREK 207
Query: 170 VDLEKSAKTKENRKKSTNMKDVSSKMASRDKD 201
+ KTK+ +K + K K AS D
Sbjct: 208 A----TEKTKKKKKHKKHSKKKKKKAASSSPD 235
Score = 30.8 bits (68), Expect = 0.98
Identities = 16/46 (34%), Positives = 23/46 (50%)
Query: 114 EELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESP 159
EE++ +K+K +E E+ KK KK KK A S +SP
Sbjct: 192 EEVRAKKKKSSEEREKATEKTKKKKKHKKHSKKKKKKAASSSPDSP 237
>gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]
Length = 247
Score = 50.8 bits (120), Expect = 9e-07
Identities = 36/138 (26%), Positives = 64/138 (46%), Gaps = 11/138 (7%)
Query: 90 KVLLEGPSGVAKRKTKAKVKELT---KEELKKEKEKPESRKESKNEERKKGKKEDVRKDK 146
K+L S KR+ K K K+ + + S +S++E++K+GK+ +K++
Sbjct: 79 KLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNR 138
Query: 147 KIADADLSRKESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSS--KMASRDKDDRK 204
++ S E+ KD L+K K+K+ +K ++K +S KM S DK
Sbjct: 139 SHKSSESSMSETESDSKD------SLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSS 192
Query: 205 ESRSSTRYAHLTKGNTQK 222
ES S + Y + +K
Sbjct: 193 ESLSESEYIEEVRAKKKK 210
Score = 50.4 bits (119), Expect = 1e-06
Identities = 37/120 (30%), Positives = 61/120 (50%), Gaps = 5/120 (4%)
Query: 107 KVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPKGKKDRE 166
K+ E K+EL+K +EK S ES +++R++ KKE +K + + + S +S D E
Sbjct: 64 KMNENWKKELEKHREKLLSGSESSSKKRQRKKKEK-KKSGRYSSSSSSSSDSSSSSSDSE 122
Query: 167 KEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDD---RKESRSSTRYAHLTKGNTQKR 223
E K K K+NR ++ + S+ S KD +K+S+ T KG ++KR
Sbjct: 123 DEDKKQGKRRKKKKNRSHKSSESSM-SETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKR 181
Score = 42.7 bits (99), Expect = 2e-04
Identities = 24/102 (23%), Positives = 54/102 (52%), Gaps = 1/102 (0%)
Query: 110 ELTKEELKKEKEKPESRKESKNEERKKGKKE-DVRKDKKIADADLSRKESPKGKKDREKE 168
E KE+L+K+K+ ++ E + + + KKE + ++K ++ ++ S K+ + KK+++K
Sbjct: 42 EEVKEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKKS 101
Query: 169 KVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSST 210
S+ + ++ S++ +D K R K + S S+
Sbjct: 102 GRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSS 143
Score = 40.4 bits (93), Expect = 0.001
Identities = 25/114 (21%), Positives = 52/114 (45%), Gaps = 1/114 (0%)
Query: 101 KRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGK-KEDVRKDKKIADADLSRKESP 159
K++ K + K+ + E E+ +SK+ +KK K K+ K+K I RK
Sbjct: 126 KKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYS 185
Query: 160 KGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSSTRYA 213
+ K + + E + + +KKS+ ++ +++ + K +K S+ + A
Sbjct: 186 EDKPLSSESLSESEYIEEVRAKKKKSSEEREKATEKTKKKKKHKKHSKKKKKKA 239
Score = 39.7 bits (91), Expect = 0.002
Identities = 35/152 (23%), Positives = 64/152 (42%), Gaps = 11/152 (7%)
Query: 57 KAKDFRYNLSEVLQGKLGIYDADG-DGDFDVDDAKVLLEGPSGVAKRKTKAKVKELTKEE 115
K K RY+ S +D D D + + S + + ++ + +K+
Sbjct: 98 KKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDS 157
Query: 116 LKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKE------SPKGKKDREKEK 169
LKK+K+ + ++ K+ + K++ +DK ++ LS E + K K E+EK
Sbjct: 158 LKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSEEREK 217
Query: 170 VDLEKSAKTKENRKKSTNMKDVSSKMASRDKD 201
+ KTK+ +K + K K AS D
Sbjct: 218 A----TEKTKKKKKHKKHSKKKKKKAASSSPD 245
Score = 30.8 bits (68), Expect = 0.98
Identities = 16/46 (34%), Positives = 23/46 (50%)
Query: 114 EELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESP 159
EE++ +K+K +E E+ KK KK KK A S +SP
Sbjct: 202 EEVRAKKKKSSEEREKATEKTKKKKKHKKHSKKKKKKAASSSPDSP 247
>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
Length = 2039
Score = 50.4 bits (119), Expect = 1e-06
Identities = 33/105 (31%), Positives = 54/105 (51%), Gaps = 7/105 (6%)
Query: 110 ELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKE----SPKGKKDR 165
E ++ +K+ KEKPE R + K ++ +K +++ K+KKI S K+ S K +
Sbjct: 786 EKQEKHIKESKEKPEKRSQIKEKDIEKMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIK 845
Query: 166 EKEKV---DLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESR 207
EK+K+ EK K E K + +K + SR+K DRK +
Sbjct: 846 EKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDK 890
Score = 49.7 bits (117), Expect = 2e-06
Identities = 48/179 (26%), Positives = 79/179 (44%), Gaps = 9/179 (5%)
Query: 51 YEEVLAKAKDFRYNLSEVLQGKLGIYDADGDGDFDVDDAKVLLEGPSGVAKRKTKAKVKE 110
++E KDF E K I D D F+ D + G +K K K KE
Sbjct: 579 HKEKSKHQKDFHLEFGEKSNAK--IKDEDHSPTFENSDCTLKKMDKEGKTLKKHKLKHKE 636
Query: 111 LTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPKGK-KDREKEK 169
KE+ KKE E +++ K ++ K + V D++ + + + + + E E
Sbjct: 637 REKEKHKKEIE--GEKEKYKTKDSAKELQRSVEFDREFWKENFFKSDETEDLFLNMEHES 694
Query: 170 VDLEKSAKTKENRK--KSTNMKDVSSKMASRDKDD--RKESRSSTRYAHLTKGNTQKRN 224
+ LEK +K ++N K KST K VS + +++ D +KES S R + ++ N
Sbjct: 695 LTLEKKSKLEKNIKDDKSTKEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEEREN 753
Score = 38.9 bits (89), Expect = 0.004
Identities = 38/139 (27%), Positives = 61/139 (43%), Gaps = 25/139 (17%)
Query: 105 KAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVR--KDKKIADADLSRKESPKGK 162
K+K+++ K++ K KEK S++ + EER K KKE + +++KI D R+ P K
Sbjct: 700 KSKLEKNIKDD-KSTKEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEERENIPTDK 758
Query: 163 KDR------------------EKEKVDLEKSAK-TKENRKKSTNMKDVSSKMASRDKDDR 203
EKE +D+EK K KE+++K + K +K +R
Sbjct: 759 DSEFTSLGMSAIEESIGLHLVEKE-IDIEKQEKHIKESKEKPEKRSQIKEK--DIEKMER 815
Query: 204 KESRSSTRYAHLTKGNTQK 222
K + H K K
Sbjct: 816 KTFEKEKKIKHEHKSEKDK 834
Score = 38.9 bits (89), Expect = 0.004
Identities = 30/105 (28%), Positives = 54/105 (51%), Gaps = 6/105 (5%)
Query: 100 AKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESP 159
A +KT + K K + K +KEKPE + E ++K E +K+K+ +++ S+ E
Sbjct: 870 AIKKTDDREKSREKMDRKHDKEKPEKERHLA-ESKEKHLME--KKNKQSDNSEYSKSE-- 924
Query: 160 KGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRK 204
KGK + ++D ++ ++ KE+ TN K + + S D K
Sbjct: 925 KGKNKEKDRELDKKEKSRDKES-INITNSKHIQEEKKSSIVDGNK 968
Score = 38.5 bits (88), Expect = 0.005
Identities = 36/146 (24%), Positives = 62/146 (42%), Gaps = 29/146 (19%)
Query: 101 KRKTKAKVKELTKEELKKEKEKPESRKESKNEER----KKGKKEDVRKDKKIADADLSRK 156
K K A +K+ E +EK + KE +ER K K +K+K+ +++ S+
Sbjct: 864 KSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKS 923
Query: 157 ESPKGK----------KDREKEKVDLEKSAKTKENRK-------KSTNMKDVSSKMASRD 199
E K K K R+KE +++ S +E +K K+ + K +S K ++D
Sbjct: 924 EKGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKPLSLKEKTKD 983
Query: 200 --------KDDRKESRSSTRYAHLTK 217
K+ K+ + RY K
Sbjct: 984 EPLKTPDGKEKDKKDKDIDRYKERDK 1009
Score = 38.5 bits (88), Expect = 0.005
Identities = 29/112 (25%), Positives = 52/112 (46%), Gaps = 5/112 (4%)
Query: 101 KRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRK---DKKIADADLSRKE 157
K K K K +EL K+E ++KE +E KK D K +K ++ + ++ E
Sbjct: 925 KGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKPLSLKEKTKDE 984
Query: 158 SPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSS 209
K +EK+K D K + R K + ++S + + + D+ + +SS
Sbjct: 985 PLKTPDGKEKDKKD--KDIDRYKERDKHKDKIQINSLLKLKSEADKPKPKSS 1034
Score = 34.7 bits (78), Expect = 0.068
Identities = 31/99 (31%), Positives = 45/99 (45%), Gaps = 7/99 (7%)
Query: 102 RKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPKG 161
+ K K KE +E KKEK + KES N K +E+ K I D + ++ E P
Sbjct: 922 KSEKGKNKEKDRELDKKEKSRD---KESINITNSKHIQEE--KKSSIVDGNKAQHEKPLS 976
Query: 162 KKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDK 200
K EK K + K+ KE KK ++ + +DK
Sbjct: 977 LK--EKTKDEPLKTPDGKEKDKKDKDIDRYKERDKHKDK 1013
Score = 33.5 bits (75), Expect = 0.15
Identities = 34/120 (28%), Positives = 55/120 (45%), Gaps = 21/120 (17%)
Query: 102 RKTKAKVKELTKEELK---------KEKEKPE-SRKESKNEERKKGKKEDV----RKDKK 147
+K K K+K+ KE L+ K+KEK + + ESKN+E + K +V K+K+
Sbjct: 1073 KKHKEKIKQKEKERLRNRNCLELKIKDKEKTKHTPTESKNKELTRSKSSEVTDAYTKEKQ 1132
Query: 148 IADADLSRKESPKGK------KDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKD 201
DA +R +S K K L +S ++ EN K + + VS + +D
Sbjct: 1133 PKDAVSNRSQSVDTKNVMTLGKSSFVSDNSLNRSPRS-ENEKPGLSSRSVSMISVASSED 1191
Score = 32.7 bits (73), Expect = 0.26
Identities = 34/131 (25%), Positives = 60/131 (45%), Gaps = 22/131 (16%)
Query: 101 KRKTKAKVKELTKEELKKEKEKPE-SRKESKNEERKK-------------GKKEDVRKDK 146
+RKT K K++ K E K EK+K + S K +E+ K K ++ K
Sbjct: 814 ERKTFEKEKKI-KHEHKSEKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIK 872
Query: 147 KIADADLSRKESPKGKKDREKEKVD------LEKSAKTKENRKKSTNMKDVSSKMASRDK 200
K D + SR++ + K D+EK + + EK K+N++ + S K +++K
Sbjct: 873 KTDDREKSREKMDR-KHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEK 931
Query: 201 DDRKESRSSTR 211
D + + +R
Sbjct: 932 DRELDKKEKSR 942
Score = 30.8 bits (68), Expect = 0.98
Identities = 35/152 (23%), Positives = 62/152 (40%), Gaps = 31/152 (20%)
Query: 87 DDAKVLLEGPSGVAKRKTKAKVKELTK------EELKKEKEKPESRKE--------SKNE 132
D ++E P G RK+K K+ +K ++ KE ++ S K S+NE
Sbjct: 16 DSDSNMVEKPYG---RKSKDKIASYSKTPKIERSDVSKEMKEKSSMKRKLPFTISPSRNE 72
Query: 133 ERKKGKKEDVRKDKKIADADLSRKESPK----GKKDREKEKVDLEKSAKTKENRKKST-- 186
ER +++ + KK ++K +P G E++++ L ++N ST
Sbjct: 73 ERDSDTEKEGPEKKKTKKEAGNKKSTPVSILFGYPLSERKQMALLMQMTARDNSPDSTPN 132
Query: 187 --------NMKDVSSKMASRDKDDRKESRSST 210
K SS +DK +++ R T
Sbjct: 133 HPSQTTPAQKKTPSSSSRQKDKVNKRNERGET 164
Score = 29.3 bits (64), Expect = 2.8
Identities = 33/141 (23%), Positives = 51/141 (36%), Gaps = 16/141 (11%)
Query: 98 GVAKRKTKAKVKELTKEELKKEKEKPESRK-------------ESKNEERKKGKKEDVRK 144
G KRK K + K +ELK+EKE E+ + E EE K +
Sbjct: 447 GKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEGNFRKSFSPKD 506
Query: 145 DKKIADADLSRKESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRK 204
D + +S +SPK +++ K TK ++ + + D + +
Sbjct: 507 DTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSPGSSEMSLQPDLVRYDNTESE 566
Query: 205 ---ESRSSTRYAHLTKGNTQK 222
ES S H K QK
Sbjct: 567 FLPESSSVKSCKHKEKSKHQK 587
Score = 28.9 bits (63), Expect = 3.7
Identities = 36/154 (23%), Positives = 65/154 (42%), Gaps = 31/154 (20%)
Query: 100 AKRKTKAKVKELTKEELKKEKEKPESRKESKNEER------KKGKKEDVRKDKKIADADL 153
A+ + +KE TK+E K + E K+ K+ +R K K + K ++AD
Sbjct: 969 AQHEKPLSLKEKTKDEPLKTPDGKEKDKKDKDIDRYKERDKHKDKIQINSLLKLKSEADK 1028
Query: 154 SR-KESPKGKKDREKEK------------------VDLE-----KSAKTKENRKKSTNMK 189
+ K SP K R KEK DLE K K K +K+ ++
Sbjct: 1029 PKPKSSPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHKKHKEKIKQKEKERLR 1088
Query: 190 DVSS-KMASRDKDDRKESRSSTRYAHLTKGNTQK 222
+ + ++ +DK+ K + + ++ LT+ + +
Sbjct: 1089 NRNCLELKIKDKEKTKHTPTESKNKELTRSKSSE 1122
>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
Length = 2062
Score = 50.4 bits (119), Expect = 1e-06
Identities = 33/105 (31%), Positives = 54/105 (51%), Gaps = 7/105 (6%)
Query: 110 ELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKE----SPKGKKDR 165
E ++ +K+ KEKPE R + K ++ +K +++ K+KKI S K+ S K +
Sbjct: 809 EKQEKHIKESKEKPEKRSQIKEKDIEKMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIK 868
Query: 166 EKEKV---DLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESR 207
EK+K+ EK K E K + +K + SR+K DRK +
Sbjct: 869 EKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDK 913
Score = 49.7 bits (117), Expect = 2e-06
Identities = 48/179 (26%), Positives = 79/179 (44%), Gaps = 9/179 (5%)
Query: 51 YEEVLAKAKDFRYNLSEVLQGKLGIYDADGDGDFDVDDAKVLLEGPSGVAKRKTKAKVKE 110
++E KDF E K I D D F+ D + G +K K K KE
Sbjct: 602 HKEKSKHQKDFHLEFGEKSNAK--IKDEDHSPTFENSDCTLKKMDKEGKTLKKHKLKHKE 659
Query: 111 LTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPKGK-KDREKEK 169
KE+ KKE E +++ K ++ K + V D++ + + + + + E E
Sbjct: 660 REKEKHKKEIE--GEKEKYKTKDSAKELQRSVEFDREFWKENFFKSDETEDLFLNMEHES 717
Query: 170 VDLEKSAKTKENRK--KSTNMKDVSSKMASRDKDD--RKESRSSTRYAHLTKGNTQKRN 224
+ LEK +K ++N K KST K VS + +++ D +KES S R + ++ N
Sbjct: 718 LTLEKKSKLEKNIKDDKSTKEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEEREN 776
Score = 38.9 bits (89), Expect = 0.004
Identities = 38/139 (27%), Positives = 61/139 (43%), Gaps = 25/139 (17%)
Query: 105 KAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVR--KDKKIADADLSRKESPKGK 162
K+K+++ K++ K KEK S++ + EER K KKE + +++KI D R+ P K
Sbjct: 723 KSKLEKNIKDD-KSTKEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEERENIPTDK 781
Query: 163 KDR------------------EKEKVDLEKSAK-TKENRKKSTNMKDVSSKMASRDKDDR 203
EKE +D+EK K KE+++K + K +K +R
Sbjct: 782 DSEFTSLGMSAIEESIGLHLVEKE-IDIEKQEKHIKESKEKPEKRSQIKEK--DIEKMER 838
Query: 204 KESRSSTRYAHLTKGNTQK 222
K + H K K
Sbjct: 839 KTFEKEKKIKHEHKSEKDK 857
Score = 38.9 bits (89), Expect = 0.004
Identities = 30/105 (28%), Positives = 54/105 (51%), Gaps = 6/105 (5%)
Query: 100 AKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESP 159
A +KT + K K + K +KEKPE + E ++K E +K+K+ +++ S+ E
Sbjct: 893 AIKKTDDREKSREKMDRKHDKEKPEKERHLA-ESKEKHLME--KKNKQSDNSEYSKSE-- 947
Query: 160 KGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRK 204
KGK + ++D ++ ++ KE+ TN K + + S D K
Sbjct: 948 KGKNKEKDRELDKKEKSRDKES-INITNSKHIQEEKKSSIVDGNK 991
Score = 38.5 bits (88), Expect = 0.005
Identities = 36/146 (24%), Positives = 62/146 (42%), Gaps = 29/146 (19%)
Query: 101 KRKTKAKVKELTKEELKKEKEKPESRKESKNEER----KKGKKEDVRKDKKIADADLSRK 156
K K A +K+ E +EK + KE +ER K K +K+K+ +++ S+
Sbjct: 887 KSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKS 946
Query: 157 ESPKGK----------KDREKEKVDLEKSAKTKENRK-------KSTNMKDVSSKMASRD 199
E K K K R+KE +++ S +E +K K+ + K +S K ++D
Sbjct: 947 EKGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKPLSLKEKTKD 1006
Query: 200 --------KDDRKESRSSTRYAHLTK 217
K+ K+ + RY K
Sbjct: 1007 EPLKTPDGKEKDKKDKDIDRYKERDK 1032
Score = 38.5 bits (88), Expect = 0.005
Identities = 29/112 (25%), Positives = 52/112 (46%), Gaps = 5/112 (4%)
Query: 101 KRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRK---DKKIADADLSRKE 157
K K K K +EL K+E ++KE +E KK D K +K ++ + ++ E
Sbjct: 948 KGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKPLSLKEKTKDE 1007
Query: 158 SPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSS 209
K +EK+K D K + R K + ++S + + + D+ + +SS
Sbjct: 1008 PLKTPDGKEKDKKD--KDIDRYKERDKHKDKIQINSLLKLKSEADKPKPKSS 1057
Score = 34.7 bits (78), Expect = 0.068
Identities = 31/99 (31%), Positives = 45/99 (45%), Gaps = 7/99 (7%)
Query: 102 RKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPKG 161
+ K K KE +E KKEK + KES N K +E+ K I D + ++ E P
Sbjct: 945 KSEKGKNKEKDRELDKKEKSRD---KESINITNSKHIQEE--KKSSIVDGNKAQHEKPLS 999
Query: 162 KKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDK 200
K EK K + K+ KE KK ++ + +DK
Sbjct: 1000 LK--EKTKDEPLKTPDGKEKDKKDKDIDRYKERDKHKDK 1036
Score = 33.5 bits (75), Expect = 0.15
Identities = 34/120 (28%), Positives = 55/120 (45%), Gaps = 21/120 (17%)
Query: 102 RKTKAKVKELTKEELK---------KEKEKPE-SRKESKNEERKKGKKEDV----RKDKK 147
+K K K+K+ KE L+ K+KEK + + ESKN+E + K +V K+K+
Sbjct: 1096 KKHKEKIKQKEKERLRNRNCLELKIKDKEKTKHTPTESKNKELTRSKSSEVTDAYTKEKQ 1155
Query: 148 IADADLSRKESPKGK------KDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKD 201
DA +R +S K K L +S ++ EN K + + VS + +D
Sbjct: 1156 PKDAVSNRSQSVDTKNVMTLGKSSFVSDNSLNRSPRS-ENEKPGLSSRSVSMISVASSED 1214
Score = 32.7 bits (73), Expect = 0.26
Identities = 34/131 (25%), Positives = 60/131 (45%), Gaps = 22/131 (16%)
Query: 101 KRKTKAKVKELTKEELKKEKEKPE-SRKESKNEERKK-------------GKKEDVRKDK 146
+RKT K K++ K E K EK+K + S K +E+ K K ++ K
Sbjct: 837 ERKTFEKEKKI-KHEHKSEKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIK 895
Query: 147 KIADADLSRKESPKGKKDREKEKVD------LEKSAKTKENRKKSTNMKDVSSKMASRDK 200
K D + SR++ + K D+EK + + EK K+N++ + S K +++K
Sbjct: 896 KTDDREKSREKMDR-KHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEK 954
Query: 201 DDRKESRSSTR 211
D + + +R
Sbjct: 955 DRELDKKEKSR 965
Score = 29.3 bits (64), Expect = 2.8
Identities = 33/141 (23%), Positives = 51/141 (36%), Gaps = 16/141 (11%)
Query: 98 GVAKRKTKAKVKELTKEELKKEKEKPESRK-------------ESKNEERKKGKKEDVRK 144
G KRK K + K +ELK+EKE E+ + E EE K +
Sbjct: 470 GKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEGNFRKSFSPKD 529
Query: 145 DKKIADADLSRKESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRK 204
D + +S +SPK +++ K TK ++ + + D + +
Sbjct: 530 DTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSPGSSEMSLQPDLVRYDNTESE 589
Query: 205 ---ESRSSTRYAHLTKGNTQK 222
ES S H K QK
Sbjct: 590 FLPESSSVKSCKHKEKSKHQK 610
Score = 28.9 bits (63), Expect = 3.7
Identities = 36/154 (23%), Positives = 65/154 (42%), Gaps = 31/154 (20%)
Query: 100 AKRKTKAKVKELTKEELKKEKEKPESRKESKNEER------KKGKKEDVRKDKKIADADL 153
A+ + +KE TK+E K + E K+ K+ +R K K + K ++AD
Sbjct: 992 AQHEKPLSLKEKTKDEPLKTPDGKEKDKKDKDIDRYKERDKHKDKIQINSLLKLKSEADK 1051
Query: 154 SR-KESPKGKKDREKEK------------------VDLE-----KSAKTKENRKKSTNMK 189
+ K SP K R KEK DLE K K K +K+ ++
Sbjct: 1052 PKPKSSPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHKKHKEKIKQKEKERLR 1111
Query: 190 DVSS-KMASRDKDDRKESRSSTRYAHLTKGNTQK 222
+ + ++ +DK+ K + + ++ LT+ + +
Sbjct: 1112 NRNCLELKIKDKEKTKHTPTESKNKELTRSKSSE 1145
>gi|41055989 M-phase phosphoprotein 8 [Homo sapiens]
Length = 860
Score = 50.4 bits (119), Expect = 1e-06
Identities = 43/165 (26%), Positives = 79/165 (47%), Gaps = 18/165 (10%)
Query: 48 LVDYEEVLA--KAKDFRYNLSEVLQGKLGIYDADGDGDFDVDDAKVLLEGPSGVAKRKTK 105
L+++ + +A KAK R ++ + I++A+ D D + E S K+K
Sbjct: 103 LLEFRKKIAENKAKAVRKDIQRLSLNN-DIFEANSDSDQQSETK----EDTSPKKKKKKL 157
Query: 106 AKVKELTKEELKKEKEKPESRKESKNEERKKGKKE---DVRKDKKIADADLSRKESPKGK 162
+ +E + ++LKK+K K K+ + + + D+R K+I++A KES K K
Sbjct: 158 RQREEKSPDDLKKKKAKAGKLKDKSKPDLESSLESLVFDLRTKKRISEAKEELKESKKPK 217
Query: 163 KDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESR 207
KD KE +L+K K ++D+ +K K++RK +
Sbjct: 218 KDEVKETKELKK--------VKKGEIRDLKTKTREDPKENRKTKK 254
Score = 41.2 bits (95), Expect = 7e-04
Identities = 30/109 (27%), Positives = 54/109 (49%), Gaps = 9/109 (8%)
Query: 103 KTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPKGK 162
+TK ++ E KEELK+ K KP+ + + +E KK KK ++R D +E PK
Sbjct: 198 RTKKRISE-AKEELKESK-KPKKDEVKETKELKKVKKGEIR------DLKTKTREDPKEN 249
Query: 163 KDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSSTR 211
+ +KEK +E +++ + + + S+ D + K++ S R
Sbjct: 250 RKTKKEKF-VESQVESESSVLNDSPFPEDDSEGLHSDSREEKQNTKSAR 297
Score = 40.8 bits (94), Expect = 0.001
Identities = 44/151 (29%), Positives = 73/151 (48%), Gaps = 21/151 (13%)
Query: 81 DGDFDVDDAKVLLEGPSGVAKRKTKAKVKELTKEELKKEK--EKPESRKESKNEE----- 133
D F DD++ L S K+ TK+ +E +++ E EKP S E+
Sbjct: 271 DSPFPEDDSEGL-HSDSREEKQNTKS-ARERAGQDMGLEHGFEKPLDSAMSAEEDTDVRG 328
Query: 134 -RKKG---KKEDVRKDKKIAD--ADLSRKESPKGKK--DREKEKVDLEK----SAKTKEN 181
RKK K ED R+++K+ + A L +K PK ++ DR K +LEK SA+T +
Sbjct: 329 RRKKKTPRKAEDTRENRKLENKNAFLEKKTVPKKQRNQDRSKSAAELEKLMPVSAQTPKG 388
Query: 182 RKKSTNMKDVSSKMASRDKDDRKESRSSTRY 212
R+ S + + S ++ + + K + S +Y
Sbjct: 389 RRLSGEERGLWSTDSAEEDKETKRNESKEKY 419
Score = 37.0 bits (84), Expect = 0.014
Identities = 28/99 (28%), Positives = 53/99 (53%), Gaps = 8/99 (8%)
Query: 110 ELTKEELKKE-KEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPKGKKD---- 164
E KE + E KEK + R +S EE+ + + + ++ K+I +A K +P+ K D
Sbjct: 405 EEDKETKRNESKEKYQKRHDSDKEEKGRKEPKGLKTLKEIRNAFDLFKLTPEEKNDVSEN 464
Query: 165 -REKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDD 202
R++E++ L+ KT ++ K N + + + +RD+ D
Sbjct: 465 NRKREEIPLD--FKTIDDHKTKENKQSLKERRNTRDETD 501
Score = 32.7 bits (73), Expect = 0.26
Identities = 37/155 (23%), Positives = 62/155 (40%), Gaps = 33/155 (21%)
Query: 102 RKTKAKVKELTKEELKKEKEK-PESRKESKN---------EERKKGKKEDVRKDK----- 146
R K K +E KE K +KEK ES+ ES++ E+ +G D R++K
Sbjct: 236 RDLKTKTREDPKENRKTKKEKFVESQVESESSVLNDSPFPEDDSEGLHSDSREEKQNTKS 295
Query: 147 ----------------KIADADLSRKESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKD 190
K D+ +S +E + R+K+ K+ T+ENRK
Sbjct: 296 ARERAGQDMGLEHGFEKPLDSAMSAEEDTDVRGRRKKKTP--RKAEDTRENRKLENKNAF 353
Query: 191 VSSKMASRDKDDRKESRSSTRYAHLTKGNTQKRNG 225
+ K + + ++ S+S+ L + Q G
Sbjct: 354 LEKKTVPKKQRNQDRSKSAAELEKLMPVSAQTPKG 388
Score = 30.8 bits (68), Expect = 0.98
Identities = 30/141 (21%), Positives = 60/141 (42%), Gaps = 20/141 (14%)
Query: 103 KTKAKVKELTKEELKKEKEKP-ESRKESKNEERKKGKKEDVRKDKKIADADL-------- 153
K ++K++ K E++ K K E KE++ +++K + V + + +
Sbjct: 222 KETKELKKVKKGEIRDLKTKTREDPKENRKTKKEKFVESQVESESSVLNDSPFPEDDSEG 281
Query: 154 ----SRKESPKGKKDREKEKVDL------EKSAKTKENRKKSTNMKDVSSKMASRDKDDR 203
SR+E K RE+ D+ EK + + ++ T+++ K R +D
Sbjct: 282 LHSDSREEKQNTKSARERAGQDMGLEHGFEKPLDSAMSAEEDTDVRGRRKKKTPRKAEDT 341
Query: 204 KESRS-STRYAHLTKGNTQKR 223
+E+R + A L K K+
Sbjct: 342 RENRKLENKNAFLEKKTVPKK 362
>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
Length = 248
Score = 50.1 bits (118), Expect = 2e-06
Identities = 33/133 (24%), Positives = 59/133 (44%), Gaps = 9/133 (6%)
Query: 94 EGPSGVAKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADL 153
E S +RK K K K + S +S++EE+K+GK+ +K++ +
Sbjct: 85 ESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQS 144
Query: 154 SRKESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDR---KESRSST 210
S ES K+ K+K K+K+ +K +++ +S K DD+ ES S +
Sbjct: 145 STHESESESKESVKKK------KKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSES 198
Query: 211 RYAHLTKGNTQKR 223
Y + ++R
Sbjct: 199 DYEEDVQAKKKRR 211
Score = 48.5 bits (114), Expect = 5e-06
Identities = 36/115 (31%), Positives = 60/115 (52%), Gaps = 10/115 (8%)
Query: 107 KVKELTKEELKKEKEKPESRKES---KNEERKKGKKEDVRKDKKIADADL------SRKE 157
K+ E K+EL+K +EK S ES K E +KK KK+ R + +D S E
Sbjct: 64 KMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDE 123
Query: 158 SPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDR-KESRSSTR 211
K K R+K+K KS+++ + +S + + V K S+D+ ++ K+ RS ++
Sbjct: 124 EKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSK 178
Score = 38.5 bits (88), Expect = 0.005
Identities = 25/105 (23%), Positives = 51/105 (48%), Gaps = 4/105 (3%)
Query: 110 ELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPKGKKDREKEK 169
E K++L+ +K ++ E + + + KKE + +K+ + S + + KK R+K+
Sbjct: 42 EEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKS 101
Query: 170 VDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDR----KESRSST 210
S+ + ++ S++ +D K R K + K S+SST
Sbjct: 102 CRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSST 146
Score = 38.5 bits (88), Expect = 0.005
Identities = 28/124 (22%), Positives = 54/124 (43%), Gaps = 7/124 (5%)
Query: 101 KRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGK-KEDVRKDKKIADADLSRKESP 159
K++ K + K+ + + ES ESK +KK K K++ K+K + RK+S
Sbjct: 125 KKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSY 184
Query: 160 KGKKDREKE---KVDLEKSAKTKENRK---KSTNMKDVSSKMASRDKDDRKESRSSTRYA 213
K E + D E+ + K+ R+ + + V K + K K+ + + +
Sbjct: 185 PDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSS 244
Query: 214 HLTK 217
H ++
Sbjct: 245 HKSR 248
Score = 34.3 bits (77), Expect = 0.088
Identities = 16/44 (36%), Positives = 29/44 (65%), Gaps = 1/44 (2%)
Query: 100 AKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVR 143
AK+K + + +E KE++KK+K+K + +K SK +++K G R
Sbjct: 206 AKKKRRCEEREQAKEKVKKKKKK-QHKKHSKKKKKKSGSSHKSR 248
Score = 30.0 bits (66), Expect = 1.7
Identities = 24/95 (25%), Positives = 40/95 (42%), Gaps = 2/95 (2%)
Query: 132 EERKKGKKEDVRKDKKIADADLSRKESPKGKKDREKEKV--DLEKSAKTKENRKKSTNMK 189
EE KK + K +A+ + E+ K + ++ +EK+ E S+K +E +KK
Sbjct: 42 EEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKS 101
Query: 190 DVSSKMASRDKDDRKESRSSTRYAHLTKGNTQKRN 224
SS +S S S K +K+N
Sbjct: 102 CRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKN 136
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 49.7 bits (117), Expect = 2e-06
Identities = 40/135 (29%), Positives = 69/135 (51%), Gaps = 10/135 (7%)
Query: 100 AKRKTKAKVKELTK-EELKKEKEKPESRKESKNEE-RKKGKKEDVR----KDKKIADADL 153
++ ++++K K+ K + +E+ + SR SK+E RK+G K D + K KK D D
Sbjct: 342 SRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDR 401
Query: 154 SRKESPKGKKDREKEKVDLEKSAK--TKENRKKSTNMKDVS-SKMASRDKDD-RKESRSS 209
S+ SP +E+E E S + E+ TN + S S+ S+ K + ESRS
Sbjct: 402 SQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSR 461
Query: 210 TRYAHLTKGNTQKRN 224
++ A T+ ++ R+
Sbjct: 462 SKSASKTRSRSKSRS 476
Score = 43.1 bits (100), Expect = 2e-04
Identities = 29/111 (26%), Positives = 53/111 (47%), Gaps = 5/111 (4%)
Query: 102 RKTKAKVKELTKEELKKEKEKPESRKESKNEERKKG-KKEDVRKDKKIADADLSRKESPK 160
R + +V+E + + + + + +S ++S++ R KG + R K D RK S +
Sbjct: 303 RSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSRE 362
Query: 161 GKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSSTR 211
+ R + + E+S K R + K SSK ++ DR +SRS +R
Sbjct: 363 ESRSRSRSRSKSERSRKRGSKR----DSKAGSSKKKKKEDTDRSQSRSPSR 409
Score = 40.8 bits (94), Expect = 0.001
Identities = 31/137 (22%), Positives = 57/137 (41%), Gaps = 14/137 (10%)
Query: 100 AKRKTKAKVKELTKEELKKEK------EKPESRKESKNEERKKGKKEDVRKDKKIADADL 153
++ ++K++ + ++ KKEK EK SR S + R K K + K + +
Sbjct: 226 SRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGK 285
Query: 154 SRKESPKGKKDREK-------EKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKES 206
+ SP K + K +V+ EK R + +++ S+ S+ R S
Sbjct: 286 PKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKG-GSRSRS 344
Query: 207 RSSTRYAHLTKGNTQKR 223
RS ++ KG + R
Sbjct: 345 RSRSKSKDKRKGRKRSR 361
Score = 36.6 bits (83), Expect = 0.018
Identities = 29/130 (22%), Positives = 63/130 (48%), Gaps = 12/130 (9%)
Query: 95 GPSGVAKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLS 154
G S + K++++ + ++ K + + +SR SK E+ + KE R + A S
Sbjct: 209 GSSKSSHSKSRSRSRSGSRSR-SKSRSRSQSRSRSKKEKSRSPSKEKSRS--RSHSAGKS 265
Query: 155 RKESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSSTRYAH 214
R +S KD+ +EK+ + ++R S + S+ S+++ +E R S
Sbjct: 266 RSKS----KDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGS----- 316
Query: 215 LTKGNTQKRN 224
+++G +Q+++
Sbjct: 317 VSRGRSQEKS 326
Score = 35.4 bits (80), Expect = 0.040
Identities = 23/109 (21%), Positives = 54/109 (49%), Gaps = 15/109 (13%)
Query: 118 KEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPK------GKKDREKEKVD 171
+ + + S+ + K + RK+ ++E + + + ++ SRK K K ++KE D
Sbjct: 341 RSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTD 400
Query: 172 LEKS-------AKTKENRKKSTNMKD--VSSKMASRDKDDRKESRSSTR 211
+S +K +E+ K ++ ++ S+ A +++ R SRS+++
Sbjct: 401 RSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSK 449
Score = 32.3 bits (72), Expect = 0.34
Identities = 39/198 (19%), Positives = 78/198 (39%), Gaps = 28/198 (14%)
Query: 45 WFDLVDYEEVLAKAKDFRYNLSEVLQGKLGIYDADGDGDFDVDDAKVLLEGPSGVAKRKT 104
W DL DY + +A + Y + + G+ + D K LE G
Sbjct: 117 WQDLKDY---MRQAGEVTYADAHKGRKNEGVIEF-----VSYSDMKRALEKLDGTEVNGR 168
Query: 105 KAKVKELTKEELKKEKEKPESRKESKNEERKK-GKKEDVRKDKKIADADLSRKESPKGKK 163
K ++ E K ++ + SR S++ R + +K R + SR S G +
Sbjct: 169 KIRLVE-DKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSR 227
Query: 164 DREKEKVDLEKSAKTKENRKKSTNMKDV--------SSKMASRDKDDRK----------E 205
R K + + +++K+ + +S + + S+ S+D+ + K +
Sbjct: 228 SRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPK 287
Query: 206 SRSSTRYAHLTKGNTQKR 223
SRS +R+ +K ++ +
Sbjct: 288 SRSPSRHKSKSKSRSRSQ 305
>gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo
sapiens]
Length = 1150
Score = 49.7 bits (117), Expect = 2e-06
Identities = 35/136 (25%), Positives = 64/136 (47%), Gaps = 10/136 (7%)
Query: 83 DFDVDDAKVLLEGPSGVAKRKTKAKVKELTKEELKKEKE------KPESRK----ESKNE 132
DF V K LL P K++ K K+ +++ K+E++ KP+ RK + K E
Sbjct: 781 DFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKE 840
Query: 133 ERKKGKKEDVRKDKKIADADLSRKESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVS 192
+R + KKED RKD D + + E E+ + E+ + +E K + +D++
Sbjct: 841 DRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDIN 900
Query: 193 SKMASRDKDDRKESRS 208
R D+++ ++
Sbjct: 901 RYCKERPSKDKEKEKT 916
Score = 43.9 bits (102), Expect = 1e-04
Identities = 24/101 (23%), Positives = 48/101 (47%)
Query: 111 LTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPKGKKDREKEKV 170
L ++E KKEK+K + E K+++ ++ + D K K+ D K+ + ++ +E ++
Sbjct: 793 LPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRK 852
Query: 171 DLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSSTR 211
D K E + ++ A ++DDR E + R
Sbjct: 853 DDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKR 893
Score = 39.7 bits (91), Expect = 0.002
Identities = 21/72 (29%), Positives = 42/72 (58%), Gaps = 3/72 (4%)
Query: 101 KRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPK 160
KRK +K + T+E+ +++ P +E+++EE + ++E ++D K D++R +
Sbjct: 850 KRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDK---RDINRYCKER 906
Query: 161 GKKDREKEKVDL 172
KD+EKEK +
Sbjct: 907 PSKDKEKEKTQM 918
Score = 38.1 bits (87), Expect = 0.006
Identities = 38/145 (26%), Positives = 66/145 (45%), Gaps = 10/145 (6%)
Query: 44 VWFDLVDYEEVLAKAKDFRYNLSEVLQGKLGIYDADGDGDFDVDDAKVLLEGPSGVAKRK 103
VW L E ++ ++ L E LQG+ D + D + D + P+ +K
Sbjct: 576 VWHCLPTRSEWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLD 635
Query: 104 TKA-KVKELTKE------ELKKEKEKPESR--KESKNEERKKGKKEDVRKDKKIADADLS 154
K KV +L KE K K + +R K+ K EE+K+ +KE + K +K D D
Sbjct: 636 PKTMKVNDLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKE-LEKSEKEEDEDDD 694
Query: 155 RKESPKGKKDREKEKVDLEKSAKTK 179
RK +++ K + ++E+ + +
Sbjct: 695 RKSEDDKEEEERKRQEEIERQRRER 719
Score = 30.0 bits (66), Expect = 1.7
Identities = 21/93 (22%), Positives = 42/93 (45%), Gaps = 5/93 (5%)
Query: 101 KRKTKAKVKELTKEELKKEKEKPESRK-----ESKNEERKKGKKEDVRKDKKIADADLSR 155
K K + + K+E + E++K + RK + + EE + D + ++ D + R
Sbjct: 826 KPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDR 885
Query: 156 KESPKGKKDREKEKVDLEKSAKTKENRKKSTNM 188
E K+D +++ K +K+ K+ T M
Sbjct: 886 DEEEMTKRDDKRDINRYCKERPSKDKEKEKTQM 918
Score = 28.5 bits (62), Expect = 4.8
Identities = 11/55 (20%), Positives = 29/55 (52%)
Query: 93 LEGPSGVAKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKK 147
L+ PS + R + K++ +E+E+ R ++ +RK+ ++ R++++
Sbjct: 295 LDPPSRFSGRNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERE 349
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 49.3 bits (116), Expect = 3e-06
Identities = 26/103 (25%), Positives = 61/103 (59%), Gaps = 2/103 (1%)
Query: 109 KELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPKGKKDREKE 168
K+L +E+ KKEKE+ E KE + ER++ ++ + R+ ++ + + R++ + +++RE++
Sbjct: 289 KKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERD 348
Query: 169 KVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSSTR 211
+ D +++ + +R + + + + R+K DR SR +R
Sbjct: 349 R-DRDRTKERDRDRDRERDRDRDRERSSDRNK-DRSRSREKSR 389
Score = 46.6 bits (109), Expect = 2e-05
Identities = 25/118 (21%), Positives = 59/118 (50%), Gaps = 1/118 (0%)
Query: 88 DAKVLLEGPSGVAKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKK 147
D LE G +++ + KE + E ++E+E+ +E + E ++ +KE R+ ++
Sbjct: 286 DTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERER 345
Query: 148 IADADLSRKESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKE 205
D D R + +DRE+++ D ++ + N+ +S + + + R+++ +E
Sbjct: 346 ERDRDRDRTKERDRDRDRERDR-DRDRERSSDRNKDRSRSREKSRDRERERERERERE 402
Score = 43.5 bits (101), Expect = 1e-04
Identities = 35/131 (26%), Positives = 63/131 (48%), Gaps = 10/131 (7%)
Query: 104 TKAKVKELTKEELKKE---KEKPESRKESKNEERKKGKKEDVRKDKKIADADLSR-KESP 159
TK + + EE K++ +E + R K E +KGKKE R++ + + R +E
Sbjct: 260 TKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERE 319
Query: 160 KGKKDREKEKVDLEKSAKTKENRKKSTNMKDVS-SKMASRDKD-----DRKESRSSTRYA 213
+ +++RE+E+ + K KE ++ +D +K RD+D DR RSS R
Sbjct: 320 RERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNK 379
Query: 214 HLTKGNTQKRN 224
++ + R+
Sbjct: 380 DRSRSREKSRD 390
Score = 43.1 bits (100), Expect = 2e-04
Identities = 26/106 (24%), Positives = 55/106 (51%), Gaps = 5/106 (4%)
Query: 101 KRKTKAKVKELTKE-ELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESP 159
+R+ + + +E +E E ++EKEK R+ ++ +R + K+ D +D++ D D R+ S
Sbjct: 317 ERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRE-RDRDRDRERSS 375
Query: 160 KGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKE 205
KDR + + EKS + R++ + + R+++ +E
Sbjct: 376 DRNKDRSRSR---EKSRDRERERERERERERERERERERERERERE 418
Score = 43.1 bits (100), Expect = 2e-04
Identities = 24/117 (20%), Positives = 60/117 (51%), Gaps = 3/117 (2%)
Query: 101 KRKTKAKVKELTKE-ELKKEKEKPESRKESKNEERKKGKKEDVRKDK-KIADADLSRKES 158
+ + + + +E KE E ++E+E+ R +K +R + ++ D +D+ + +D + R S
Sbjct: 325 REREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRS 384
Query: 159 PKGKKDREKEKV-DLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSSTRYAH 214
+ +DRE+E+ + E+ + + R++ + + R+KD +++ A+
Sbjct: 385 REKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAY 441
Score = 43.1 bits (100), Expect = 2e-04
Identities = 31/130 (23%), Positives = 63/130 (48%), Gaps = 13/130 (10%)
Query: 101 KRKTKAKVKELTKE-ELKKEKEKPESRKESKNEERKKGKKEDVRKD-----------KKI 148
+ + + + +E +E E ++E+E+ R+ + ER+K KK D +D +K+
Sbjct: 391 REREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKL 450
Query: 149 ADADLSRKESPKGKKDREKEKV-DLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESR 207
+ + + +E K + RE++K + EK A+ +E R++ + K D DD ++
Sbjct: 451 REKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDP 510
Query: 208 SSTRYAHLTK 217
R + L K
Sbjct: 511 KYYRGSALQK 520
Score = 41.6 bits (96), Expect = 6e-04
Identities = 22/108 (20%), Positives = 59/108 (54%), Gaps = 4/108 (3%)
Query: 101 KRKTKAKVKELTKE---ELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKE 157
K K + ++++ +E E ++E+E+ E +E + E ++ +KE R+ ++ D D +++
Sbjct: 298 KEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKER 357
Query: 158 SPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKE 205
++R++++ D E+S+ ++R +S + R+++ +E
Sbjct: 358 DRDRDRERDRDR-DRERSSDRNKDRSRSREKSRDRERERERERERERE 404
Score = 36.2 bits (82), Expect = 0.023
Identities = 29/148 (19%), Positives = 61/148 (41%), Gaps = 34/148 (22%)
Query: 110 ELTKEELKKEKEKPESRKESKNEERKKGKKEDV-------------------------RK 144
E+ E E P +S ++KK KKED+ +
Sbjct: 212 EVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFRRFPVAPLIPYPLITKEDINAIEMEE 271
Query: 145 DKK-IADADLS-------RKESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMA 196
DK+ + ++S + E KGKK++E+++++ E+ + +E ++ + +
Sbjct: 272 DKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERERER 331
Query: 197 SRDKDDRKESRSSTRYAHLTKGNTQKRN 224
R+++ KE R R + T++R+
Sbjct: 332 EREREKEKE-RERERERDRDRDRTKERD 358
Score = 35.4 bits (80), Expect = 0.040
Identities = 31/137 (22%), Positives = 61/137 (44%), Gaps = 23/137 (16%)
Query: 77 DADGDGDFDVD-DAKVLLEGPSGVAKRKTKAKVKELTKE-ELKKEKEKPESRKESKNEER 134
D D D + D D D + + ++ + K++ +E +E E ++E+E+ R+ + ER
Sbjct: 358 DRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERER 417
Query: 135 KKGKKEDVRKDKKIADADLSRKESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSK 194
++ ++ + KDKK +DRE+++ D E RK +++ +
Sbjct: 418 EREREREREKDKK---------------RDREEDEED------AYERRKLERKLREKEAA 456
Query: 195 MASRDKDDRKESRSSTR 211
R K+ R TR
Sbjct: 457 YQERLKNWEIRERKKTR 473
Score = 27.7 bits (60), Expect = 8.3
Identities = 26/121 (21%), Positives = 53/121 (43%), Gaps = 19/121 (15%)
Query: 81 DGDFDVDDAKVLLEGPSGVAKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKE 140
D D D DD K +++ + + KE+ +E +++EK EE ++ ++
Sbjct: 502 DYDDDRDDPKYYR---GSALQKRLRDREKEMEADERDRKREK---------EELEEIRQR 549
Query: 141 DVRKDKKIADADLSRKE-------SPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSS 193
+ + DA+L R E P+ K++ E E+ + EK K ++ + ++
Sbjct: 550 LLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQ 609
Query: 194 K 194
K
Sbjct: 610 K 610
>gi|168229156 NFKB activating protein [Homo sapiens]
Length = 415
Score = 49.3 bits (116), Expect = 3e-06
Identities = 33/123 (26%), Positives = 51/123 (41%), Gaps = 4/123 (3%)
Query: 77 DADGDGDFDVDDAKVLLEGPSGVAKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKK 136
+ D D V+D + S + K K +KE KK ++K K SK + +K
Sbjct: 154 EPDSDEHTPVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKK----KSSKRKHKKY 209
Query: 137 GKKEDVRKDKKIADADLSRKESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMA 196
+ D D + +D K K K +EK+K K K K ++K D SSK +
Sbjct: 210 SEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKES 269
Query: 197 SRD 199
+
Sbjct: 270 QEE 272
Score = 44.3 bits (103), Expect = 9e-05
Identities = 35/106 (33%), Positives = 49/106 (46%), Gaps = 10/106 (9%)
Query: 105 KAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPKGKKD 164
K+ T EE KK+K S++ SK +KK K RK KK ++ S +S D
Sbjct: 170 KSTTSASTSEEEKKKKSS-RSKERSKKRRKKKSSK---RKHKKYSEDSDSDSDSETDSSD 225
Query: 165 REKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSST 210
+ ++ K AK KE +KK + K R K RKES S+
Sbjct: 226 EDNKR--RAKKAKKKEKKKKHRSKK----YKKKRSKKSRKESSDSS 265
Score = 37.0 bits (84), Expect = 0.014
Identities = 28/90 (31%), Positives = 45/90 (50%), Gaps = 6/90 (6%)
Query: 76 YDADGDGDFDVDDAKVLLEGPSGVAKRKTKAKVKELTKEELKKEKEKPESRKESKNEERK 135
Y D D D D + + K K K K K+ ++ KK++ K +SRKES + K
Sbjct: 209 YSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSK-KSRKESSDSSSK 267
Query: 136 KGKKEDVR---KDKKIAD--ADLSRKESPK 160
+ ++E + KD+ A+ +DL E+PK
Sbjct: 268 ESQEEFLENPWKDRTKAEEPSDLIGPEAPK 297
Score = 31.6 bits (70), Expect = 0.57
Identities = 21/106 (19%), Positives = 42/106 (39%), Gaps = 15/106 (14%)
Query: 119 EKEKPESRKESKNEERK---------------KGKKEDVRKDKKIADADLSRKESPKGKK 163
+KE+ ES ++ + ER+ K + D + + D + + +
Sbjct: 119 DKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTS 178
Query: 164 DREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSS 209
+ EK+K ++K+ RKK ++ + D D E+ SS
Sbjct: 179 EEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSS 224
Score = 28.9 bits (63), Expect = 3.7
Identities = 23/113 (20%), Positives = 46/113 (40%), Gaps = 14/113 (12%)
Query: 101 KRKTKAKVKELTKEELKKEKEKPES--------------RKESKNEERKKGKKEDVRKDK 146
+R K + K+ +K + KK E +S R+ K ++++K KK +K K
Sbjct: 191 ERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYK 250
Query: 147 KIADADLSRKESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRD 199
K ++ S K+ ++E ++ +TK + + S+D
Sbjct: 251 KKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAEEPSDLIGPEAPKTLTSQD 303
>gi|155030242 WD repeat domain 60 [Homo sapiens]
Length = 1066
Score = 49.3 bits (116), Expect = 3e-06
Identities = 41/136 (30%), Positives = 67/136 (49%), Gaps = 12/136 (8%)
Query: 81 DGDFDVDDA-KVLLEGPSGVAKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKK 139
D + DD K L SG +K + K + K+L KE E + PE + E R +
Sbjct: 10 DDTWKADDLRKHLWAIQSGGSKEERKHREKKLRKES---EMDLPEHK-----EPRCRDPD 61
Query: 140 EDVRKDKKIADADLSRKESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRD 199
+D R ++A+ + KESP+G++DR++++ + + AK +E K ++ + K SR
Sbjct: 62 QDARSRDRVAEVHTA-KESPRGERDRDRQR-ERRRDAKDREKEKLKEKHRE-AEKSHSRG 118
Query: 200 KDDRKESRSSTRYAHL 215
KD KE R L
Sbjct: 119 KDREKEKDRRARKEEL 134
Score = 38.1 bits (87), Expect = 0.006
Identities = 26/108 (24%), Positives = 53/108 (49%), Gaps = 4/108 (3%)
Query: 102 RKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGK--KEDVRKDKKIADADLSRKESP 159
R K + K T+E+ +K ++ + K EER K K KE D + +++ RKE
Sbjct: 223 RDNKHREKSSTREKREKYSKEKSNSFSDKGEERHKEKRHKEGFHFDDERHQSNVDRKEKS 282
Query: 160 KGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMAS--RDKDDRKE 205
+ R++E + E + +++ T+ + + + + +DKD R++
Sbjct: 283 AKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNHGKDKDSRRK 330
Score = 36.2 bits (82), Expect = 0.023
Identities = 25/101 (24%), Positives = 36/101 (35%)
Query: 111 LTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPKGKKDREKEKV 170
L KEE ++ KP K +E K K S K + K+ R KE
Sbjct: 206 LYKEEGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEERHKEKRHKEGF 265
Query: 171 DLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSSTR 211
+ +K + KD K S++ + R SS R
Sbjct: 266 HFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKR 306
Score = 34.7 bits (78), Expect = 0.068
Identities = 29/152 (19%), Positives = 63/152 (41%), Gaps = 7/152 (4%)
Query: 59 KDFRYNLSEVLQGKLGIYDADGDGDFDVDDAKVLLEGPSGVAKRKTKAKVKELTKEELKK 118
K+ +L E + + D D V + E P G + + + +E ++ +
Sbjct: 43 KESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKESPRG---ERDRDRQRERRRDAKDR 99
Query: 119 EKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSR---KESPKGKKDREKEKVDLEKS 175
EKEK + + + +GK + KD++ +L + + G++ R+++ ++
Sbjct: 100 EKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLGQETRDRQLLE-RAE 158
Query: 176 AKTKENRKKSTNMKDVSSKMASRDKDDRKESR 207
K + K + KD S+ D++ R R
Sbjct: 159 RKGRSVSKVRSEEKDEDSERGDEDRERRYRER 190
Score = 32.3 bits (72), Expect = 0.34
Identities = 22/119 (18%), Positives = 53/119 (44%), Gaps = 10/119 (8%)
Query: 103 KTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPKGK 162
+++ +V E+ + E+ R+ + + K +KE +++ + A+ SR + + +
Sbjct: 65 RSRDRVAEVHTAKESPRGERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKE 124
Query: 163 KDREKEKVDLEKS----------AKTKENRKKSTNMKDVSSKMASRDKDDRKESRSSTR 211
KDR K +L ++ + ++ +++ SK+ S +KD+ E R
Sbjct: 125 KDRRARKEELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDR 183
>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
sapiens]
Length = 956
Score = 48.9 bits (115), Expect = 3e-06
Identities = 32/112 (28%), Positives = 58/112 (51%), Gaps = 12/112 (10%)
Query: 101 KRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPK 160
K + + + KE KEE K+ KE+ + +KE + E ++K ++E KD+K + E +
Sbjct: 349 KLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEK------EKAEKQR 402
Query: 161 GKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSSTRY 212
K++R KE+ + AK +E RK K+ ++ +K + E TR+
Sbjct: 403 LKEERRKERQE-ALEAKLEEKRK-----KEEEKRLREEEKRIKAEKAEITRF 448
Score = 47.0 bits (110), Expect = 1e-05
Identities = 32/90 (35%), Positives = 52/90 (57%), Gaps = 5/90 (5%)
Query: 100 AKRKTKAKVKE---LTKEELKKEKEKPESRKE-SKNEERKKGKKEDVRKDKKIADADLSR 155
A+R+ K K+KE KEE KK+KE+ + KE + E+R+K +KE K + + R
Sbjct: 352 AEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKER 411
Query: 156 KESPKGKKDREKEKVDLEKSAKTKENRKKS 185
+E+ + K + EK K + EK + +E R K+
Sbjct: 412 QEALEAKLE-EKRKKEEEKRLREEEKRIKA 440
Score = 39.7 bits (91), Expect = 0.002
Identities = 30/103 (29%), Positives = 49/103 (47%), Gaps = 7/103 (6%)
Query: 109 KELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPKGKKDREKE 168
+E ++LK E+ E KE EE K+ K+E K KK + +L KE + ++ EKE
Sbjct: 341 QERLGKQLKLRAEREE--KEKLKEEAKRAKEE--AKKKKEEEKELKEKERREKREKDEKE 396
Query: 169 KVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSSTR 211
K + + + KE R+K + R K++ K R +
Sbjct: 397 KAEKQ---RLKEERRKERQEALEAKLEEKRKKEEEKRLREEEK 436
Score = 38.1 bits (87), Expect = 0.006
Identities = 32/133 (24%), Positives = 61/133 (45%), Gaps = 21/133 (15%)
Query: 94 EGPSGVAKRK-------TKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDK 146
EGP K+ T ++ +TK+ +K EK + R + ++ + GK+ +R ++
Sbjct: 297 EGPPAPPKQHSSTSPFPTSTPLRRITKKFVKGSTEKNKLRLQ--RDQERLGKQLKLRAER 354
Query: 147 ----KIADADLSRKESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDD 202
K+ + KE K KK+ EKE + E+ K +++ K+ + R K++
Sbjct: 355 EEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQ--------RLKEE 406
Query: 203 RKESRSSTRYAHL 215
R++ R A L
Sbjct: 407 RRKERQEALEAKL 419
Score = 35.4 bits (80), Expect = 0.040
Identities = 27/100 (27%), Positives = 50/100 (50%), Gaps = 7/100 (7%)
Query: 87 DDAKVLLEGPSGVAKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDK 146
++AK E + + + K KE ++ K EKEK E K+ EER+K ++E +
Sbjct: 362 EEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAE--KQRLKEERRKERQEALE--- 416
Query: 147 KIADADLSRKESPKGKKDREKEKVDLEKSAKTKENRKKST 186
A + RK+ + + E++++ EK+ T+ +K T
Sbjct: 417 --AKLEEKRKKEEEKRLREEEKRIKAEKAEITRFFQKPKT 454
>gi|125656165 THO complex 2 [Homo sapiens]
Length = 1593
Score = 48.5 bits (114), Expect = 5e-06
Identities = 41/124 (33%), Positives = 63/124 (50%), Gaps = 14/124 (11%)
Query: 95 GPSGVAKRKT-KAKVKELTKEELKKEKEK-----PESRKESKNEERKKGKKEDVRKDKKI 148
G SG K K KE KE+ K++KEK PE+R K + ++K K+E KD+K
Sbjct: 1256 GNSGSNSNKAVKENDKEKGKEKEKEKKEKTPATTPEARVLGK-DGKEKPKEERPNKDEKA 1314
Query: 149 ADADLSRKESPKGKKDREK----EKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRK 204
+ +++ +PK K++EK EK EK T N + + + K SR++D K
Sbjct: 1315 RE---TKERTPKSDKEKEKFKKEEKAKDEKFKTTVPNAESKSTQEREREKEPSRERDIAK 1371
Query: 205 ESRS 208
E +S
Sbjct: 1372 EMKS 1375
Score = 46.6 bits (109), Expect = 2e-05
Identities = 34/112 (30%), Positives = 55/112 (49%), Gaps = 3/112 (2%)
Query: 97 SGVAKRKTKAKVKELTKEELK-KEKEKPESRKESKNEERKKGK--KEDVRKDKKIADADL 153
+G + + VKE KE+ K KEKEK E + E R GK KE ++++ D
Sbjct: 1255 NGNSGSNSNKAVKENDKEKGKEKEKEKKEKTPATTPEARVLGKDGKEKPKEERPNKDEKA 1314
Query: 154 SRKESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKE 205
+ K D+EKEK E+ AK ++ + N + S++ R+K+ +E
Sbjct: 1315 RETKERTPKSDKEKEKFKKEEKAKDEKFKTTVPNAESKSTQEREREKEPSRE 1366
Score = 44.3 bits (103), Expect = 9e-05
Identities = 26/116 (22%), Positives = 53/116 (45%), Gaps = 5/116 (4%)
Query: 104 TKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPKGKK 163
+K+K +E+ K++L K +E+ R++ ++RK+ K++ D+++ R++ G
Sbjct: 1448 SKSKEREMDKKDLDKSRERSREREKKDEKDRKERKRDHSNNDREVPPDLTKRRKEENGTM 1507
Query: 164 DREKEKVDLE-----KSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSSTRYAH 214
K K + + K KE K ++ K+ S +K D+ S H
Sbjct: 1508 GVSKHKSESPCESPYPNEKDKEKNKSKSSGKEKGSDSFKSEKMDKISSGGKKESRH 1563
Score = 42.7 bits (99), Expect = 2e-04
Identities = 28/81 (34%), Positives = 43/81 (53%), Gaps = 6/81 (7%)
Query: 109 KELTKEELKKEKEKPESRKE---SKNEERKKGKKEDVRKDKKIADADLSRKESPKGKKDR 165
KE KEE + EK KE ++E++K KKE+ KD+K + + +++R
Sbjct: 1300 KEKPKEERPNKDEKARETKERTPKSDKEKEKFKKEEKAKDEKFKTTVPNAESKSTQERER 1359
Query: 166 EKE---KVDLEKSAKTKENRK 183
EKE + D+ K K+KEN K
Sbjct: 1360 EKEPSRERDIAKEMKSKENVK 1380
Score = 35.8 bits (81), Expect = 0.030
Identities = 29/92 (31%), Positives = 44/92 (47%), Gaps = 8/92 (8%)
Query: 95 GPSGVAKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLS 154
G GV+K K+++ + E KEK K +S + K + K +K D KI+
Sbjct: 1505 GTMGVSKHKSESPCESPYPNEKDKEKNKSKSSGKEKGSDSFKSEKMD-----KISSG--G 1557
Query: 155 RKESPKGK-KDREKEKVDLEKSAKTKENRKKS 185
+KES K K +KEK D + K++ K S
Sbjct: 1558 KKESRHDKEKIEKKEKRDSSGGKEEKKHHKSS 1589
Score = 35.0 bits (79), Expect = 0.052
Identities = 28/103 (27%), Positives = 49/103 (47%), Gaps = 11/103 (10%)
Query: 125 SRKESKNEERKKGKKEDVRKDKKIADADLSRKESPKGKKDREKEKVDL----EKSAKTKE 180
S K K +++KGK+++ K+KK + + GK +EK K + EK+ +TKE
Sbjct: 1262 SNKAVKENDKEKGKEKE--KEKKEKTPATTPEARVLGKDGKEKPKEERPNKDEKARETKE 1319
Query: 181 NRKKSTNMKDVSSKMASRDKDDRKESRSSTRYAHLTKGNTQKR 223
KS K+ K ++ K+ + T + +TQ+R
Sbjct: 1320 RTPKSDKEKEKFKK-----EEKAKDEKFKTTVPNAESKSTQER 1357
>gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo
sapiens]
Length = 1272
Score = 48.5 bits (114), Expect = 5e-06
Identities = 35/121 (28%), Positives = 62/121 (51%), Gaps = 9/121 (7%)
Query: 100 AKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKD--KKIADADLSRKE 157
+K + K +K K+E+ K E + +K ++++RKK KE +KD K A+ + +KE
Sbjct: 33 SKERPKDDIKLTAKKEVSKAPE--DKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKE 90
Query: 158 SPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKM-----ASRDKDDRKESRSSTRY 212
+ KK +E+E+ E+ AK ++ + + MK+ + A RKE RS +
Sbjct: 91 EEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQN 150
Query: 213 A 213
A
Sbjct: 151 A 151
Score = 47.4 bits (111), Expect = 1e-05
Identities = 35/139 (25%), Positives = 63/139 (45%), Gaps = 7/139 (5%)
Query: 83 DFDVDDAKVLLEGPSGVAKRKTKAKVKELTKEELKKEKEKPESRKES-KNEERKKGKKED 141
D + K + + P KR K K+ KE KK++EK ++ +ES K EE +K K ++
Sbjct: 40 DIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQE 99
Query: 142 VRKDKKIADADLSRKESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKD 201
+ K+ A ++E + ++E + L + A + + +K K+ ++ D
Sbjct: 100 EERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNA------PD 153
Query: 202 DRKESRSSTRYAHLTKGNT 220
R E +R K NT
Sbjct: 154 SRPEENFFSRLDSSLKKNT 172
Score = 43.1 bits (100), Expect = 2e-04
Identities = 31/119 (26%), Positives = 54/119 (45%), Gaps = 11/119 (9%)
Query: 100 AKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKD---------KKIAD 150
A+RK A ++E KEK+ E R S E K K +K+ K++ D
Sbjct: 3 AERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLED 62
Query: 151 ADLSRKESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSS 209
+++ + KKD EK K E+ +K KE +K + ++ K + K ++E ++
Sbjct: 63 DKRKKEDKERKKKDEEKVKA--EEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAA 119
Score = 30.0 bits (66), Expect = 1.7
Identities = 27/112 (24%), Positives = 48/112 (42%), Gaps = 7/112 (6%)
Query: 110 ELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPKGKKDREKEK 169
EL + ++K ES ++ ++ ER+ K + DK D S E ++D E+E
Sbjct: 981 ELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSKD---SMTEGENLEEDEEEE- 1036
Query: 170 VDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSSTRYAHLTKGNTQ 221
E A+T+E + + + + S + DD E +LT N +
Sbjct: 1037 ---EGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKE 1085
>gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo
sapiens]
Length = 1272
Score = 48.5 bits (114), Expect = 5e-06
Identities = 35/121 (28%), Positives = 62/121 (51%), Gaps = 9/121 (7%)
Query: 100 AKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKD--KKIADADLSRKE 157
+K + K +K K+E+ K E + +K ++++RKK KE +KD K A+ + +KE
Sbjct: 33 SKERPKDDIKLTAKKEVSKAPE--DKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKE 90
Query: 158 SPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKM-----ASRDKDDRKESRSSTRY 212
+ KK +E+E+ E+ AK ++ + + MK+ + A RKE RS +
Sbjct: 91 EEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQN 150
Query: 213 A 213
A
Sbjct: 151 A 151
Score = 47.4 bits (111), Expect = 1e-05
Identities = 35/139 (25%), Positives = 63/139 (45%), Gaps = 7/139 (5%)
Query: 83 DFDVDDAKVLLEGPSGVAKRKTKAKVKELTKEELKKEKEKPESRKES-KNEERKKGKKED 141
D + K + + P KR K K+ KE KK++EK ++ +ES K EE +K K ++
Sbjct: 40 DIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQE 99
Query: 142 VRKDKKIADADLSRKESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKD 201
+ K+ A ++E + ++E + L + A + + +K K+ ++ D
Sbjct: 100 EERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNA------PD 153
Query: 202 DRKESRSSTRYAHLTKGNT 220
R E +R K NT
Sbjct: 154 SRPEENFFSRLDSSLKKNT 172
Score = 43.1 bits (100), Expect = 2e-04
Identities = 31/119 (26%), Positives = 54/119 (45%), Gaps = 11/119 (9%)
Query: 100 AKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKD---------KKIAD 150
A+RK A ++E KEK+ E R S E K K +K+ K++ D
Sbjct: 3 AERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLED 62
Query: 151 ADLSRKESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSS 209
+++ + KKD EK K E+ +K KE +K + ++ K + K ++E ++
Sbjct: 63 DKRKKEDKERKKKDEEKVKA--EEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAA 119
Score = 30.0 bits (66), Expect = 1.7
Identities = 27/112 (24%), Positives = 48/112 (42%), Gaps = 7/112 (6%)
Query: 110 ELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPKGKKDREKEK 169
EL + ++K ES ++ ++ ER+ K + DK D S E ++D E+E
Sbjct: 981 ELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSKD---SMTEGENLEEDEEEE- 1036
Query: 170 VDLEKSAKTKENRKKSTNMKDVSSKMASRDKDDRKESRSSTRYAHLTKGNTQ 221
E A+T+E + + + + S + DD E +LT N +
Sbjct: 1037 ---EGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKE 1085
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 48.1 bits (113), Expect = 6e-06
Identities = 39/145 (26%), Positives = 67/145 (46%), Gaps = 11/145 (7%)
Query: 80 GDGDFDVDDAKVLLEGPSGVAKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKK 139
GD VDD L G + K KA V EELK++ K +E +ER K +K
Sbjct: 202 GDAQSRVDDH---LMGKQHMGYAKIKATV-----EELKEKLRK--RTEEPDRDERLKKEK 251
Query: 140 EDVRKDKKIADADLSRKESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSSKMASRD 199
++ + +K + + +E + +++ E+EK + K +R +S + S + SR
Sbjct: 252 QEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRS 311
Query: 200 KDDRKESRSSTRYAHLTKGNTQKRN 224
+ D K SRS R ++ + R+
Sbjct: 312 R-DHKRSRSRERRRSRSRDRRRSRS 335
Score = 44.3 bits (103), Expect = 9e-05
Identities = 31/147 (21%), Positives = 68/147 (46%), Gaps = 8/147 (5%)
Query: 86 VDDAKVLLEGPSGVAKRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKD 145
V++ K L + R + K ++ +EE +KE+E+ +E K ++ ++++ +D
Sbjct: 227 VEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARD 286
Query: 146 KKIADADLSRKESPKGKKDREKEKVDLEKSAKTKE-------NRKKSTNMKDVSSKMASR 198
++ SR DR + K ++++E +R++S + K SR
Sbjct: 287 RERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSR 346
Query: 199 DKDDRK-ESRSSTRYAHLTKGNTQKRN 224
+D R+ +SR Y H +K ++++
Sbjct: 347 SRDRRRSKSRDRKSYKHRSKSRDREQD 373
Score = 41.2 bits (95), Expect = 7e-04
Identities = 33/139 (23%), Positives = 61/139 (43%), Gaps = 31/139 (22%)
Query: 101 KRKTKAKVKELTKEELKKEKEKPESR----------------KESKNEERKKGKKEDVRK 144
+R+ + + KE ++ ++++ + SR K S++ ER++ + D R+
Sbjct: 273 RREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRR 332
Query: 145 DK-----------KIADADLSRKESPKGKKDREKEKVDLEKSAKTKENRKKSTNMKDVSS 193
+ + D S+ K K R K + D E+ K+KE K+ ++ K S
Sbjct: 333 SRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSR-DREQDRKSKEKEKRGSDDKKSSV 391
Query: 194 KMASRDK---DDRKESRSS 209
K SR+K D ES+ S
Sbjct: 392 KSGSREKQSEDTNTESKES 410
Score = 38.9 bits (89), Expect = 0.004
Identities = 24/118 (20%), Positives = 58/118 (49%), Gaps = 7/118 (5%)
Query: 101 KRKTKAKVKELTKEELKKEKEKP-ESRKESKNEERKKGKKED-----VRKDKKIADADLS 154
+R+ + + + +EE +KE+ + E RK S++ R + D R K+ +
Sbjct: 264 EREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERR 323
Query: 155 RKESPKGKKDREKEKVDLEKSAKTKENRK-KSTNMKDVSSKMASRDKDDRKESRSSTR 211
R S ++ R ++ + + +++++ R+ KS + K + SRD++ ++S+ +
Sbjct: 324 RSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEK 381
Score = 35.4 bits (80), Expect = 0.040
Identities = 24/106 (22%), Positives = 49/106 (46%), Gaps = 7/106 (6%)
Query: 118 KEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPKGKKDREKEK--VDLEKS 175
+ + + R E K+ R + ++ +D+K ++ + +K +EKEK D +KS
Sbjct: 330 RRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKS 389
Query: 176 AKTKENRKKSTNMKDVSSKMASRDKDDRKESRSSTRYAHLTKGNTQ 221
+ +R+K + + SK + D K + T ++G+TQ
Sbjct: 390 SVKSGSREKQSEDTNTESK-----ESDTKNEVNGTSEDIKSEGDTQ 430
Score = 30.4 bits (67), Expect = 1.3
Identities = 16/75 (21%), Positives = 31/75 (41%)
Query: 101 KRKTKAKVKELTKEELKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADADLSRKESPK 160
++ K + K +E+ +K KEK + + K K G +E +D + K
Sbjct: 358 RKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVN 417
Query: 161 GKKDREKEKVDLEKS 175
G + K + D + +
Sbjct: 418 GTSEDIKSEGDTQSN 432
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.126 0.344
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,445,670
Number of Sequences: 37866
Number of extensions: 399837
Number of successful extensions: 13499
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 627
Number of HSP's successfully gapped in prelim test: 770
Number of HSP's that attempted gapping in prelim test: 3865
Number of HSP's gapped (non-prelim): 5826
length of query: 225
length of database: 18,247,518
effective HSP length: 99
effective length of query: 126
effective length of database: 14,498,784
effective search space: 1826846784
effective search space used: 1826846784
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.