BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens] (950 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens] 1880 0.0 gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens] 1697 0.0 gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo sapi... 1566 0.0 gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens] 1561 0.0 gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo sapi... 1524 0.0 gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens] 1523 0.0 gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo sapi... 1520 0.0 gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens] 1517 0.0 gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens] 1517 0.0 gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo sapi... 1510 0.0 gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens] 1509 0.0 gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo sapi... 1506 0.0 gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens] 1504 0.0 gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo sapi... 1486 0.0 gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo sapi... 1382 0.0 gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo sapi... 1247 0.0 gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo sap... 1215 0.0 gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapi... 1214 0.0 gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo sapi... 1209 0.0 gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo sap... 1206 0.0 gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo sapi... 1204 0.0 gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo sapi... 1200 0.0 gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo sap... 1199 0.0 gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo sapi... 1197 0.0 gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens] 1192 0.0 gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo sap... 1182 0.0 gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo sapi... 1050 0.0 gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo sap... 795 0.0 gi|14165402 protocadherin alpha 1 isoform 3 precursor [Homo sapi... 780 0.0 gi|14277675 protocadherin gamma subfamily C, 3 isoform 1 precurs... 618 e-177 >gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1880 bits (4870), Expect = 0.0 Identities = 950/950 (100%), Positives = 950/950 (100%) Query: 1 MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD Sbjct: 61 PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 Query: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180 Query: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP Sbjct: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 Query: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG Sbjct: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300 Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 Query: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT Sbjct: 601 SGYNAWLSYELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSAPPTEGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCP 780 LRCSAPPTEGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCP Sbjct: 721 LRCSAPPTEGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCP 780 Query: 781 IMMGKAENQDLNEDHDAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840 IMMGKAENQDLNEDHDAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP Sbjct: 781 IMMGKAENQDLNEDHDAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840 Query: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR Sbjct: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900 Query: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 >gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1697 bits (4394), Expect = 0.0 Identities = 859/942 (91%), Positives = 888/942 (94%) Query: 9 LGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMAS 68 LG LLL LLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFR+AS Sbjct: 9 LGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68 Query: 69 KDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDIND 128 K DLLEV+LQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEV+D+ND Sbjct: 69 KRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVND 128 Query: 129 NPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDD 188 NPP+F V++Q++ + ESR+PDS FPLEGASDADVG+NS+LTY+LSS +YF LDV +D+ Sbjct: 129 NPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDE 188 Query: 189 NKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248 NK + L+L+KSLDRE+APAH+LFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE Sbjct: 189 NKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248 Query: 249 VRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNL 308 VRIFENADNGTTVI+LNASD DEGANGAISYSFNSLV MVIDHFSIDRNTGEIVIRGNL Sbjct: 249 VRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNL 308 Query: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV Sbjct: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368 Query: 369 IALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTAR 428 IALISVNDLDSGANGQV CSL PHVPFKLVSTFKNYYSLVLDSALDRE VSAYELVVTAR Sbjct: 369 IALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTAR 428 Query: 429 DGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488 DGGSPSLWATASLSVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA Sbjct: 429 DGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488 Query: 489 LVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548 LVSYSLVERRVGER+LSSYISVH ESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN Sbjct: 489 LVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548 Query: 549 VTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLS 608 VTLQVFVLDENDNAPALL PRVGGTGGA S+LVPRS+GAG VVAKVRAVDADSGYNAWLS Sbjct: 549 VTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLS 608 Query: 609 YELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS 668 YELQP ASS R PFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS Sbjct: 609 YELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS 668 Query: 669 LVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728 LVESGQAPKASSR S G GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA PT Sbjct: 669 LVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPT 728 Query: 729 EGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAEN 788 EG C A KPTLVCSSAVGSWSYSQQ+ QRVCSGEGPPK DLMAFSP L P + E Sbjct: 729 EGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVDVGEE 788 Query: 789 QDLNEDHDAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPE 848 QDLN DH KPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPE Sbjct: 789 QDLNVDHGLKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPE 848 Query: 849 PEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQI 908 PEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQI Sbjct: 849 PEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQI 908 Query: 909 DKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 DKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 909 DKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 >gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo sapiens] Length = 803 Score = 1566 bits (4054), Expect = 0.0 Identities = 798/798 (100%), Positives = 798/798 (100%) Query: 1 MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD Sbjct: 61 PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 Query: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180 Query: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP Sbjct: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 Query: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG Sbjct: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300 Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 Query: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT Sbjct: 601 SGYNAWLSYELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSAPPTEGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCP 780 LRCSAPPTEGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCP Sbjct: 721 LRCSAPPTEGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCP 780 Query: 781 IMMGKAENQDLNEDHDAK 798 IMMGKAENQDLNEDHDAK Sbjct: 781 IMMGKAENQDLNEDHDAK 798 >gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1561 bits (4043), Expect = 0.0 Identities = 784/950 (82%), Positives = 851/950 (89%) Query: 1 MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 M+F+ + G QCLLL LLLLAA +VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLFR+ASK DLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+ Sbjct: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 Query: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180 VEV+DINDN P+FP+ + + I ESR P S F LEGASDAD+G+NS+LTY L S+EYF L Sbjct: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180 Query: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 DVK N ++ K +GL+LKK+L+RE+ P H L +TA DGGKPELTGT QL +TVLDVNDNAP Sbjct: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240 Query: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300 FE++ Y+VR+ ENA NGT V+ +NA+D DEG N I+YSFN+ ++A ++ F +D G Sbjct: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300 Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 +I ++GN+DFE+ Y+I ++ATDKG+PPM+ HCTVL+ I+D NDNVPE+ + SLSLPV Sbjct: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360 Query: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 ED+ TVIALISV+D DSG NGQV CSLTPHVPFKLVSTFKNYYSLVLDS LDRESVSA Sbjct: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATAS+SVEVAD+NDNAPAF+Q EYTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERRVGERALSSY+SVHAESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PRVGG GGAVSELVPRS+GAG VVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQP AR PFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEP+LT Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660 Query: 661 ATATVLVSLVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASS+AS GA GPEAALVDVNVYLI+AICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSAPPTEGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCP 780 LRCSAPPTEG C KPTLVCSSAVGSWSYSQQR+QRVCSGEG PK DLMAFSPSL PCP Sbjct: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780 Query: 781 IMMGKAENQDLNEDHDAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840 I + E QD++ D AKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP Sbjct: 781 ISRDREEKQDVDVDLSAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840 Query: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR Sbjct: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900 Query: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 >gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1524 bits (3945), Expect = 0.0 Identities = 768/940 (81%), Positives = 834/940 (88%), Gaps = 6/940 (0%) Query: 14 LLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDRED 73 LLL LL+LAAW+ GSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFR+ASK D Sbjct: 14 LLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGD 73 Query: 74 LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPLF 133 LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+V+VRDINDNPP+F Sbjct: 74 LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDINDNPPIF 133 Query: 134 PVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIG 193 P ++R++I ESR P++ FPL+GASDAD+G NS LTY+L ++YF LD + + + + Sbjct: 134 PESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLEQMSSLS 193 Query: 194 LLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFE 253 L+L+K+LDREE H+L LTA+DGGKPELTGTVQLL+T+LDVNDNAP F QS Y+V + E Sbjct: 194 LVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVYKVTVLE 253 Query: 254 NADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQE 313 NA NGT VI+LNA+D D+G NG I YSF V V+ F+I+ N GEI +G LDFE++ Sbjct: 254 NAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGKLDFEEK 313 Query: 314 NLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALIS 373 LY+I ++A DKG+ PMAGHCT+LV +LD NDN PE+ +TSLSLP+RED Q +IALIS Sbjct: 314 KLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPSAIIALIS 373 Query: 374 VNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433 V+D DSG+NGQV C+LTPHVPFKLVST+KNYYSLVLDSALDRESVSAYELVVTARDGGSP Sbjct: 374 VSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433 Query: 434 SLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYS 493 SLWATAS+SV VAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA+DADAQENALVSYS Sbjct: 434 SLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQENALVSYS 493 Query: 494 LVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQV 553 LVERRVGERALSSY+SVHAESGKVYALQPLDHEELELLQFQVSARD+GVPPLGSNVTLQV Sbjct: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLGSNVTLQV 553 Query: 554 FVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSYELQP 613 FVLDENDNAPALL P G GG VSEL+PRS+GAG VVAKVRAVDADSGYNAWLSYELQ Sbjct: 554 FVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWLSYELQL 613 Query: 614 PASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESG 673 A AR PFRVGLYTGEISTTR LDE D+P HRLLVLVKDHGEPALTATATVL+SLVESG Sbjct: 614 AAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVLLSLVESG 673 Query: 674 QAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACT 733 QAP+ASSRAS GA GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGAC Sbjct: 674 QAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACA 733 Query: 734 ADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAENQDLNE 793 KPTLVCSSA GSWSYSQQRR RVCSGEGP K DLMAFSPSL PC +G AE E Sbjct: 734 PGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPC---LGSAEGTGQRE 790 Query: 794 DHD---AKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPE 850 + +PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPE Sbjct: 791 EDSECLKEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPE 850 Query: 851 AGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDK 910 AGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDK Sbjct: 851 AGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDK 910 Query: 911 SDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 SDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 911 SDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 >gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens] Length = 947 Score = 1523 bits (3943), Expect = 0.0 Identities = 773/937 (82%), Positives = 830/937 (88%), Gaps = 3/937 (0%) Query: 14 LLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDRED 73 LLL LLLLAAW+ G+GQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFR+ASK R Sbjct: 14 LLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGG 73 Query: 74 LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPLF 133 LLEVNLQNGILFVNSRIDREELC RSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPP+F Sbjct: 74 LLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPVF 133 Query: 134 PVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIG 193 P ++ + I ESR DS FPLEGASDAD+G N++LTY+LS +EYF L+ + + K +G Sbjct: 134 PATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKGLG 193 Query: 194 LLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFE 253 L+L+KSLDREEAP L LTATDGGKPELTGTVQLL+TVLD NDNAP F+++ Y+VR+ E Sbjct: 194 LILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRLLE 253 Query: 254 NADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQE 313 N NGT VI+LNASD DEG NG I YSF++ ++ V F ID TG+I+++G +DFE+ Sbjct: 254 NVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFEES 313 Query: 314 NLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALIS 373 Y+I+++ DKG P++GHC V+V + D NDNVP++ SLSLP+REDA GTVIALIS Sbjct: 314 KSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTVIALIS 373 Query: 374 VNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433 V+D D G NG V CSLT HVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP Sbjct: 374 VSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433 Query: 434 SLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYS 493 SLWATAS+SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQENALVSYS Sbjct: 434 SLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS 493 Query: 494 LVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQV 553 LVERRVGERALSSY+SVHAESGKVYALQPLDHEELELLQFQV+ARDAGVPPLGSNVTLQV Sbjct: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGSNVTLQV 553 Query: 554 FVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSYELQP 613 FVLDENDNAPALLAPR GGTGGAVSELVP S+G G VVAKVRAVDADSGYNAWLSYELQP Sbjct: 554 FVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWLSYELQP 613 Query: 614 PASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESG 673 AR PFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEPALTATATVLVSLVESG Sbjct: 614 GTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLVSLVESG 673 Query: 674 QAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACT 733 QAPKASSRA VGA GP+AALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA PTEGAC Sbjct: 674 QAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTEGACA 733 Query: 734 ADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAENQDLNE 793 KPTLVCSSAVGSWSYSQQRR RVCSGEGPPK DLMAFSPSL P + + E Sbjct: 734 PGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSL---PDSRDREDQLQTTE 790 Query: 794 DHDAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGE 853 + AKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGE Sbjct: 791 ESFAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGE 850 Query: 854 VSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDF 913 VSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDF Sbjct: 851 VSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDF 910 Query: 914 ITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 ITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 911 ITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 947 >gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo sapiens] Length = 948 Score = 1520 bits (3936), Expect = 0.0 Identities = 779/942 (82%), Positives = 827/942 (87%), Gaps = 1/942 (0%) Query: 9 LGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMAS 68 LG QCLLL LLLLAAW+VGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLFR+AS Sbjct: 8 LGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVAS 67 Query: 69 KDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDIND 128 K DLLEVNLQNGILFVNSRIDREELCGRS ECSIHLEVIVDRPLQVFHVDVEV+DIND Sbjct: 68 KRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDIND 127 Query: 129 NPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDD 188 NPP F V EQ++ I ESRL DS FPLEGASDADVG N++LTYKLS +EYF LD+ D Sbjct: 128 NPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDK 187 Query: 189 NKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248 +K L+L+K LDREE P L LTATDGGKPE TG+V LL+ VLD NDNAP F++ YE Sbjct: 188 DKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYE 247 Query: 249 VRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNL 308 V+++EN N T VIRLNASD DEG N + YSF+SLV + F I+ TGEI + + Sbjct: 248 VKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAI 307 Query: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368 DFE N Y+I +D TDKG+PPM GHCTVLV +LD+NDN PE+ +TSLSLPV+EDAQ GTV Sbjct: 308 DFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTV 367 Query: 369 IALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTAR 428 IALISV+D DSGANGQV CSLTPHVPFKLVST+KNYYSLVLDSALDRE VSAYELVVTAR Sbjct: 368 IALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTAR 427 Query: 429 DGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488 DGGSP LWATAS+SVEVAD+NDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQENA Sbjct: 428 DGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENA 487 Query: 489 LVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548 LVSYSLVERR+GER+LSSY+SVHAESGKVYALQPLDHEELELLQFQVSARD GVPPLGSN Sbjct: 488 LVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSN 547 Query: 549 VTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLS 608 +TLQVFVLDENDNAPALLA G GGAVSELV RS+ AG VVAKVRAVDADSGYNAWLS Sbjct: 548 LTLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLS 607 Query: 609 YELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS 668 YELQ A AR PFRVGLYTGEISTTR LDE DSPR RLLVLVKDHGEP+LTATATVLVS Sbjct: 608 YELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVS 667 Query: 669 LVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728 LVE QAPKASSRASVG A PE ALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA PT Sbjct: 668 LVEGSQAPKASSRASVGVA-PEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPT 726 Query: 729 EGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAEN 788 EGAC KPTLVCSSAVGSWSYSQQRRQRVCSGEG PK DLMAFSPSL PCP++ E+ Sbjct: 727 EGACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCPMVDVDGED 786 Query: 789 QDLNEDHDAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPE 848 Q + DH KPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPE Sbjct: 787 QSIGGDHSRKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPE 846 Query: 849 PEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQI 908 PEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQI Sbjct: 847 PEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQI 906 Query: 909 DKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 DKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 907 DKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 948 >gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens] Length = 936 Score = 1517 bits (3928), Expect = 0.0 Identities = 774/950 (81%), Positives = 827/950 (87%), Gaps = 14/950 (1%) Query: 1 MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 MV++ LG + LLL LLLA WK GSGQLHYS+PEEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MVYSRRGSLGSRLLLL-WLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59 Query: 61 PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLFR+ASK R DLLEVNLQNGILFVNSRIDREELC R AECSIHLEVIVDRPLQVFHV+ Sbjct: 60 PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119 Query: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180 V V+DINDNPP F +EQR+ I ESR+PDS FPLEGASD D+G+N+ L Y+L+ +EYF L Sbjct: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179 Query: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 DVK N ++ + L+L+KSLDREE H L + ATDGGKPELTGTVQLL+ VLD NDNAP Sbjct: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239 Query: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300 F++S Y VR+ ENA +GT VI+LNASD DEG N I Y F++LV V F I+ NTG Sbjct: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299 Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 EI + G LD+E N Y+I IDA DK P++GHC V+V++LD NDN PE+A+T+L LPV+ Sbjct: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359 Query: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 EDA TVIALISV+D DSGANGQV CSL PHVPFKLVSTFKNYYSLVLDSALDRESVS Sbjct: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419 Query: 421 YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATAS+SVEVAD+NDNAPAFAQP+YTVFVKENNPPGCHIFTVSAR Sbjct: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479 Query: 481 DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERRVGER LSSY+SVHAESGKVYALQPLDHEE+ELLQFQVSARDA Sbjct: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PRVGGTGGAVSELVPRS+GAG VVAKVRAVD D Sbjct: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599 Query: 601 SGYNAWLSYELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQP SAR PFRVGLYTGEISTTR LDE ++PRHRLLVLVKDHGEP LT Sbjct: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659 Query: 661 ATATVLVSLVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASSRAS GA GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA Sbjct: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719 Query: 721 LRCSAPPTEGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCP 780 LRCSA PTE CT KPTL+CSSAVGSWSYSQQRRQRVCSGE PPK DLMAFSPSL P Sbjct: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGP 779 Query: 781 IMMGKAENQDLNEDHDAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840 PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP Sbjct: 780 TSTD-------------NPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 826 Query: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR Sbjct: 827 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 886 Query: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 887 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 936 >gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1517 bits (3927), Expect = 0.0 Identities = 769/950 (80%), Positives = 834/950 (87%) Query: 1 MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 MVF+ LG + LLL LLLLAAW+VGSGQLHYS+PEEAKHGTFVGR+AQDLGLELAELV Sbjct: 1 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60 Query: 61 PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLFR+ASK DLLEVNLQNGILFVNSRIDREELC SAECSIHLE+I DRPLQVFHV+ Sbjct: 61 PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120 Query: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180 V+V+DINDNPP+F EQ + I ESRL +S FP+EGA+DAD+G+N++LTY LS S+YF L Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180 Query: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 DV+ + + +K + L L+K LDREE P +L LTATDGGKPEL GTV+LL+TVLDVNDNAP Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240 Query: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300 F+Q+ Y V + E NGT V LNASD DEG NG + +SF+S ++ + + F +D ++G Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300 Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 EI + LD+E+ Y+I + A DKG PPM+ HC VLV++LD NDN PE+A+TSL LP+R Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360 Query: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 EDA TVIALI+V+D DSGANGQV CSL PHVPFKLVSTFKNYYSLVLDSALDRES+S Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420 Query: 421 YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATA +SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERRVGERALS+Y+SVHAESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGT GAVSELVPR +GAG VVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQP A AR PFRVGLYTGEISTTRVLDEAD R+RLLVLVKDHGEPALT Sbjct: 601 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASSRASVG AGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSAPPTEGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCP 780 LRCS PPTEGA KPTLVCSSA+GSWS SQQRRQRVCS EGPPK DLMAFSP LSP Sbjct: 721 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL 780 Query: 781 IMMGKAENQDLNEDHDAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840 + E + N D PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP Sbjct: 781 NTSERNEQPEANLDLSGNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840 Query: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR Sbjct: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900 Query: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 >gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo sapiens] Length = 949 Score = 1510 bits (3910), Expect = 0.0 Identities = 772/945 (81%), Positives = 829/945 (87%), Gaps = 7/945 (0%) Query: 9 LGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMAS 68 LG L L LLLL W+VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV RLFR+AS Sbjct: 9 LGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRVAS 68 Query: 69 KDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDIND 128 K DLLEVNLQNGILFVNSRIDREELCG+SAECSIHLEVIVDRPLQVFHV+VEV+DIND Sbjct: 69 KTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDIND 128 Query: 129 NPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDD 188 NPP+F + EQ++LI ES+ DS FPLEGASDAD+ N++LTY+LS +EYF LD N Sbjct: 129 NPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNGKQ 188 Query: 189 NKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248 K++ L+LKKSLDRE+ P NL LTATDGGKPELTGTV+LLV VLDVNDN P F++SEY+ Sbjct: 189 IKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSEYK 248 Query: 249 VRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNL 308 V + ENA T V++LNA+DRDEG NG ++YS S + F++D+N GE+ + G L Sbjct: 249 VSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVNGTL 307 Query: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368 D+E+ YKI + ATDKG PPMAGHCTV V ILD NDN PE+A+TSLSLPVREDAQ TV Sbjct: 308 DYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPSTV 367 Query: 369 IALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTAR 428 IALISV+D DSG NGQV CSLTPHVPFKLVSTFKNYYSLVLDSALDRE+V AYELVVTAR Sbjct: 368 IALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVTAR 427 Query: 429 DGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488 DGGSPSLWATA +SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA Sbjct: 428 DGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 487 Query: 489 LVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548 LVSYSLVERR+G+RALSSY+SVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL SN Sbjct: 488 LVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLSSN 547 Query: 549 VTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLS 608 VTLQVFVLDENDNAPALLA + G GGAV++LVPRS+GAG VVAKVRAVDADSGYNAWLS Sbjct: 548 VTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNAWLS 607 Query: 609 YELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS 668 YELQP A +R PFRVGLYTGEISTTR LDEADSPRHRLLVLVKDHGEPALTATATVLVS Sbjct: 608 YELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVS 667 Query: 669 LVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728 LVESGQAPKASSR GAA PEAALVDVNVYLIIAIC VSSLLVLTLLLYTAL SA PT Sbjct: 668 LVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSATPT 727 Query: 729 EGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGK--- 785 EGAC KPTLVCS AVGSWSYSQQRRQRVCS EGPPK DLMAFSPSL P+ + K Sbjct: 728 EGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSL---PLGLNKEEE 784 Query: 786 AENQDLNEDHDAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSA 845 E Q+ +H +PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSA Sbjct: 785 GERQEPGSNHPGQPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSA 844 Query: 846 TPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTN 905 TPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTN Sbjct: 845 TPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTN 904 Query: 906 SQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 SQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 905 SQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 949 >gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens] Length = 948 Score = 1509 bits (3908), Expect = 0.0 Identities = 768/937 (81%), Positives = 830/937 (88%), Gaps = 4/937 (0%) Query: 15 LLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDREDL 74 LL LLLLAAW+VGSGQL YSVPEEAKHGTFVGRIAQDLGLEL ELVPRLFR+ASK DL Sbjct: 15 LLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDL 74 Query: 75 LEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPLFP 134 LEVNLQNGILFVNSRIDREELCGRSAECSIH+EVIVDRPLQVFHV+VEV+DINDNPP+FP Sbjct: 75 LEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDNPPIFP 134 Query: 135 VEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIGL 194 + + + ESRL DS FPLEGASDAD+G N++L+YKLSSSE+F LD++ N + ++ + L Sbjct: 135 MTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELSESLSL 194 Query: 195 LLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFEN 254 +L KSLDREE NL L ATDGGKPELTGTVQ+L+ VLDVNDN PTF QS Y+V++ EN Sbjct: 195 VLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLEN 254 Query: 255 ADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQEN 314 NGT V++LNASD DEG N I YS S V++ + F+ID +GEI +G LD+E+ Sbjct: 255 TANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAK 314 Query: 315 LYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALISV 374 Y+I + ATDKG P M+GHC + ++++D NDN PE+++TSLSLP+ E+A GTVIALI+V Sbjct: 315 SYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITV 374 Query: 375 NDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434 +D DSG NG V CSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS Sbjct: 375 SDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434 Query: 435 LWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSL 494 LWAT S+S+EVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQENALVSYSL Sbjct: 435 LWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494 Query: 495 VERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVF 554 VERRVGERALSSY+SVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLGSNVTLQVF Sbjct: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVF 554 Query: 555 VLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSYELQPP 614 VLDENDNAPALLAPR G GAVSELVP S+GAG VVAKVRAVDADSGYNAWLSYELQ Sbjct: 555 VLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLG 614 Query: 615 ASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674 SAR PFRVGLYTGEISTTR LDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ Sbjct: 615 TGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674 Query: 675 APKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACTA 734 APKASSRA VGAAG EA LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS PPTEGA Sbjct: 675 APKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTEGARAP 734 Query: 735 DKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAENQDLNE- 793 KPTLVCSSAVGSWSYSQQRRQRVCSGE PPK DLMAFSPSLS P AE + L+E Sbjct: 735 GKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP---DSAEEKQLSES 791 Query: 794 DHDAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGE 853 ++ KPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGE Sbjct: 792 EYVGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGE 851 Query: 854 VSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDF 913 VSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDF Sbjct: 852 VSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDF 911 Query: 914 ITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 ITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 912 ITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 948 >gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1506 bits (3898), Expect = 0.0 Identities = 761/939 (81%), Positives = 824/939 (87%) Query: 12 QCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDR 71 Q LLL LL+LA W VGSGQLHYSVPEEA+HGTFVGRIAQDLGLELAELVPRLF++ SK R Sbjct: 12 QPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGR 71 Query: 72 EDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPP 131 DLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEV+DINDNPP Sbjct: 72 GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPP 131 Query: 132 LFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQ 191 +FP ++ + I ESR DS FPLEGASDAD+G N++LTY+LS +EYF LDV ++ K Sbjct: 132 VFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKP 191 Query: 192 IGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRI 251 +GL+L+K LDREE P +L LTATDGGKPELTGTVQLL+TVLD NDNAP F+++ Y V++ Sbjct: 192 LGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKL 251 Query: 252 FENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFE 311 EN GT VI NASD DEG NG I YSF+S V+ + F +D +G I + G++DFE Sbjct: 252 PENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFE 311 Query: 312 QENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIAL 371 + +KI ++A DKG PP+AGHCT+LV ++D NDN P++ + +LS+PV+EDAQ GTVIAL Sbjct: 312 ESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIAL 371 Query: 372 ISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG 431 ISV DLD+ ANGQV CSLTPHVPFKLVST+KNYYSLVLD ALDRESVSAYELVVTARDGG Sbjct: 372 ISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGG 431 Query: 432 SPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVS 491 SPSLWATA +SVEVAD+NDNAPAFAQ EYTVFVKENNPPGCHIFTVSARDADAQENALVS Sbjct: 432 SPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVS 491 Query: 492 YSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL 551 YSLVERR+GER+LSSY+SVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL Sbjct: 492 YSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL 551 Query: 552 QVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSYEL 611 QVFVLDENDNAPALL PR+ GT GAVSE+V RS+GAG VV KVRAVDADSGYNAWLSYEL Sbjct: 552 QVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLSYEL 611 Query: 612 QPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVE 671 QP +SA PFRVGLYTGEISTTR LDE D+PR RLLVLVKDHGEPALTATATVLVSLVE Sbjct: 612 QPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVSLVE 671 Query: 672 SGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGA 731 SGQAPK+SSRASVGA GPE LVDVNVYLIIAICAVSSLLVLTLLLYT LRCSA PTEG Sbjct: 672 SGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMPTEGE 731 Query: 732 CTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAENQDL 791 C KPTLVCSSAVGSWSYSQQRRQRVCSGEG K DLMAFSP LSPC + Sbjct: 732 CAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCAGSTERTGEPSA 791 Query: 792 NEDHDAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEA 851 + D KPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEA Sbjct: 792 SSDSTGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEA 851 Query: 852 GEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKS 911 GEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKS Sbjct: 852 GEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKS 911 Query: 912 DFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 DFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 912 DFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 >gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens] Length = 937 Score = 1504 bits (3894), Expect = 0.0 Identities = 767/941 (81%), Positives = 826/941 (87%), Gaps = 13/941 (1%) Query: 10 GKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASK 69 G + LLL +++LAAW+ G GQLHYSVPEEAKHG FVGRIAQDLGLELAELVPRLFR K Sbjct: 10 GGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCK 69 Query: 70 DREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDN 129 R DLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIV+RPLQVFHVDVEV+DINDN Sbjct: 70 FRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDN 129 Query: 130 PPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDN 189 PP+FP ++ + I ESR DS FPLEGASDAD+G N++LTY+LS +EYF LDV ++ Sbjct: 130 PPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQV 189 Query: 190 KQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249 K +GL+L+K LDREE P +L LTATDGGKPELTGTVQLL+TVLD NDNAP F+++ Y V Sbjct: 190 KPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTV 249 Query: 250 RIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLD 309 ++ EN GT VI NASD DEG NG I YSF+S V+ + F +D +G I + G++D Sbjct: 250 KLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMD 309 Query: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369 FE+ +KI ++A DKG PP+AGHCTVLV ++D NDN P++ LTSLSLP+ EDAQ GTVI Sbjct: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369 Query: 370 ALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429 LISV D D G NGQV CSLTP VPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD Sbjct: 370 TLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429 Query: 430 GGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489 GGSPSLWATAS+SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL Sbjct: 430 GGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNAL 489 Query: 490 VSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 VSYSLVE RVGERALSSY+SVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV Sbjct: 490 VSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 Query: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSY 609 TLQVFVLDENDNAPALLAPRVGGTGGAV ELVPRS+GAG VVAKVRAVDADSGYNAWLSY Sbjct: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609 Query: 610 ELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669 ELQP A+ A PFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEP+LTATATVLVSL Sbjct: 610 ELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSL 669 Query: 670 VESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTE 729 VESGQAPKASSRAS+G AGPE LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAP +E Sbjct: 670 VESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSE 729 Query: 730 GACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAENQ 789 GAC+ KPTLVCSSAVGSWS+SQQRRQRVCSGEGPPK DLMAFSPSL P +N Sbjct: 730 GACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP---SSTDN- 785 Query: 790 DLNEDHDAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 849 PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP Sbjct: 786 ---------PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 836 Query: 850 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 909 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID Sbjct: 837 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 896 Query: 910 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 897 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 937 >gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo sapiens] Length = 941 Score = 1486 bits (3848), Expect = 0.0 Identities = 766/941 (81%), Positives = 816/941 (86%), Gaps = 9/941 (0%) Query: 10 GKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASK 69 G Q LLL LLLLAAW+VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFR+ASK Sbjct: 10 GSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69 Query: 70 DREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDN 129 DLLEVNLQNGILFVNSRIDRE+LCGRSAECSIHLEVIVDRPLQVFHVDVEV+DINDN Sbjct: 70 RHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDN 129 Query: 130 PPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDN 189 PP+F EQ+V + ES DS FPLEGASDAD+G NS+LTY LS +E F L +K D + Sbjct: 130 PPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDKS 189 Query: 190 KQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249 L+L+K LDRE+ P NL L DGGKPELTG+VQ+ +TVLDVNDN P F++ Y+V Sbjct: 190 ILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYKV 249 Query: 250 RIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLD 309 + EN N T VI+LNASD DEG NG ISY ++ FSI+ +TGEI I G LD Sbjct: 250 VLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGELD 309 Query: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369 FE+ N Y+I ++A DKG P MAGH VLV +LD NDNVPE+ +TSLSLPV+EDAQ GTVI Sbjct: 310 FEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTVI 369 Query: 370 ALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429 ALISV+D DSGANGQV CSLTPHVPFKLVST+KNYYSLVLDSALDRESVSAYELVVTARD Sbjct: 370 ALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARD 429 Query: 430 GGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489 GGSPSLWATA +SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL Sbjct: 430 GGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNAL 489 Query: 490 VSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 VSYSLVERRVGE ALSSY+SVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV Sbjct: 490 VSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 Query: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSY 609 TLQVFVLDENDNAPALLA G GGAVSELVPRS+GAG VVAKVRAVDADSGYNAWLSY Sbjct: 550 TLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609 Query: 610 ELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669 ELQP A A PF VGLYTGEISTTR+LDEAD+PRHRLLVLVKDHGEPALT+TATVLVSL Sbjct: 610 ELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLVSL 669 Query: 670 VESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTE 729 VE+GQAPK SSRASVGA PEAALVD+NVYLIIAICAVSSLLVLTLLLYTALRCSAPPT Sbjct: 670 VENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPPTV 729 Query: 730 GACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAENQ 789 C KPTLVCSSAVGSWSYSQQRRQRVCS E PPK DLMAFSPSL + Sbjct: 730 SRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQ-------LSRED 782 Query: 790 DLNEDHDAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 849 LN ++PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP Sbjct: 783 CLNP--PSEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 840 Query: 850 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 909 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID Sbjct: 841 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 900 Query: 910 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 901 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 941 >gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo sapiens] Length = 814 Score = 1382 bits (3578), Expect = 0.0 Identities = 707/790 (89%), Positives = 736/790 (93%) Query: 9 LGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMAS 68 LG LLL LLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFR+AS Sbjct: 9 LGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68 Query: 69 KDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDIND 128 K DLLEV+LQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEV+D+ND Sbjct: 69 KRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVND 128 Query: 129 NPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDD 188 NPP+F V++Q++ + ESR+PDS FPLEGASDADVG+NS+LTY+LSS +YF LDV +D+ Sbjct: 129 NPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDE 188 Query: 189 NKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248 NK + L+L+KSLDRE+APAH+LFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE Sbjct: 189 NKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248 Query: 249 VRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNL 308 VRIFENADNGTTVI+LNASD DEGANGAISYSFNSLV MVIDHFSIDRNTGEIVIRGNL Sbjct: 249 VRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNL 308 Query: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV Sbjct: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368 Query: 369 IALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTAR 428 IALISVNDLDSGANGQV CSL PHVPFKLVSTFKNYYSLVLDSALDRE VSAYELVVTAR Sbjct: 369 IALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTAR 428 Query: 429 DGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488 DGGSPSLWATASLSVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA Sbjct: 429 DGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488 Query: 489 LVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548 LVSYSLVERRVGER+LSSYISVH ESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN Sbjct: 489 LVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548 Query: 549 VTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLS 608 VTLQVFVLDENDNAPALL PRVGGTGGA S+LVPRS+GAG VVAKVRAVDADSGYNAWLS Sbjct: 549 VTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLS 608 Query: 609 YELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS 668 YELQP ASS R PFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS Sbjct: 609 YELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS 668 Query: 669 LVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728 LVESGQAPKASSR S G GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA PT Sbjct: 669 LVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPT 728 Query: 729 EGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAEN 788 EG C A KPTLVCSSAVGSWSYSQQ+ QRVCSGEGPPK DLMAFSP L P + E Sbjct: 729 EGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVDVGEE 788 Query: 789 QDLNEDHDAK 798 QDLN DH K Sbjct: 789 QDLNVDHGLK 798 >gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo sapiens] Length = 824 Score = 1247 bits (3227), Expect = 0.0 Identities = 632/798 (79%), Positives = 699/798 (87%) Query: 1 MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 M+F+ + G QCLLL LLLLAA +VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLFR+ASK DLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+ Sbjct: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 Query: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180 VEV+DINDN P+FP+ + + I ESR P S F LEGASDAD+G+NS+LTY L S+EYF L Sbjct: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180 Query: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 DVK N ++ K +GL+LKK+L+RE+ P H L +TA DGGKPELTGT QL +TVLDVNDNAP Sbjct: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240 Query: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300 FE++ Y+VR+ ENA NGT V+ +NA+D DEG N I+YSFN+ ++A ++ F +D G Sbjct: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300 Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 +I ++GN+DFE+ Y+I ++ATDKG+PPM+ HCTVL+ I+D NDNVPE+ + SLSLPV Sbjct: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360 Query: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 ED+ TVIALISV+D DSG NGQV CSLTPHVPFKLVSTFKNYYSLVLDS LDRESVSA Sbjct: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATAS+SVEVAD+NDNAPAF+Q EYTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERRVGERALSSY+SVHAESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PRVGG GGAVSELVPRS+GAG VVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQP AR PFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEP+LT Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660 Query: 661 ATATVLVSLVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASS+AS GA GPEAALVDVNVYLI+AICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSAPPTEGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCP 780 LRCSAPPTEG C KPTLVCSSAVGSWSYSQQR+QRVCSGEG PK DLMAFSPSL PCP Sbjct: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780 Query: 781 IMMGKAENQDLNEDHDAK 798 I + E QD++ D AK Sbjct: 781 ISRDREEKQDVDVDLSAK 798 >gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo sapiens] Length = 807 Score = 1215 bits (3144), Expect = 0.0 Identities = 616/781 (78%), Positives = 681/781 (87%), Gaps = 3/781 (0%) Query: 14 LLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDRED 73 LLL LL+LAAW+ GSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFR+ASK D Sbjct: 14 LLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGD 73 Query: 74 LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPLF 133 LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+V+VRDINDNPP+F Sbjct: 74 LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDINDNPPIF 133 Query: 134 PVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIG 193 P ++R++I ESR P++ FPL+GASDAD+G NS LTY+L ++YF LD + + + + Sbjct: 134 PESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLEQMSSLS 193 Query: 194 LLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFE 253 L+L+K+LDREE H+L LTA+DGGKPELTGTVQLL+T+LDVNDNAP F QS Y+V + E Sbjct: 194 LVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVYKVTVLE 253 Query: 254 NADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQE 313 NA NGT VI+LNA+D D+G NG I YSF V V+ F+I+ N GEI +G LDFE++ Sbjct: 254 NAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGKLDFEEK 313 Query: 314 NLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALIS 373 LY+I ++A DKG+ PMAGHCT+LV +LD NDN PE+ +TSLSLP+RED Q +IALIS Sbjct: 314 KLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPSAIIALIS 373 Query: 374 VNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433 V+D DSG+NGQV C+LTPHVPFKLVST+KNYYSLVLDSALDRESVSAYELVVTARDGGSP Sbjct: 374 VSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433 Query: 434 SLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYS 493 SLWATAS+SV VAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA+DADAQENALVSYS Sbjct: 434 SLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQENALVSYS 493 Query: 494 LVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQV 553 LVERRVGERALSSY+SVHAESGKVYALQPLDHEELELLQFQVSARD+GVPPLGSNVTLQV Sbjct: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLGSNVTLQV 553 Query: 554 FVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSYELQP 613 FVLDENDNAPALL P G GG VSEL+PRS+GAG VVAKVRAVDADSGYNAWLSYELQ Sbjct: 554 FVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWLSYELQL 613 Query: 614 PASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESG 673 A AR PFRVGLYTGEISTTR LDE D+P HRLLVLVKDHGEPALTATATVL+SLVESG Sbjct: 614 AAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVLLSLVESG 673 Query: 674 QAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACT 733 QAP+ASSRAS GA GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGAC Sbjct: 674 QAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACA 733 Query: 734 ADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAENQDLNE 793 KPTLVCSSA GSWSYSQQRR RVCSGEGP K DLMAFSPSL PC +G AE E Sbjct: 734 PGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPC---LGSAEGTGQRE 790 Query: 794 D 794 + Sbjct: 791 E 791 >gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapiens] Length = 816 Score = 1214 bits (3140), Expect = 0.0 Identities = 622/780 (79%), Positives = 675/780 (86%), Gaps = 1/780 (0%) Query: 1 MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 MV++ LG + LLL LLLA WK GSGQLHYS+PEEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MVYSRRGSLGSRLLLL-WLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59 Query: 61 PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLFR+ASK R DLLEVNLQNGILFVNSRIDREELC R AECSIHLEVIVDRPLQVFHV+ Sbjct: 60 PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119 Query: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180 V V+DINDNPP F +EQR+ I ESR+PDS FPLEGASD D+G+N+ L Y+L+ +EYF L Sbjct: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179 Query: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 DVK N ++ + L+L+KSLDREE H L + ATDGGKPELTGTVQLL+ VLD NDNAP Sbjct: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239 Query: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300 F++S Y VR+ ENA +GT VI+LNASD DEG N I Y F++LV V F I+ NTG Sbjct: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299 Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 EI + G LD+E N Y+I IDA DK P++GHC V+V++LD NDN PE+A+T+L LPV+ Sbjct: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359 Query: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 EDA TVIALISV+D DSGANGQV CSL PHVPFKLVSTFKNYYSLVLDSALDRESVS Sbjct: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419 Query: 421 YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATAS+SVEVAD+NDNAPAFAQP+YTVFVKENNPPGCHIFTVSAR Sbjct: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479 Query: 481 DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERRVGER LSSY+SVHAESGKVYALQPLDHEE+ELLQFQVSARDA Sbjct: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PRVGGTGGAVSELVPRS+GAG VVAKVRAVD D Sbjct: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599 Query: 601 SGYNAWLSYELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQP SAR PFRVGLYTGEISTTR LDE ++PRHRLLVLVKDHGEP LT Sbjct: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659 Query: 661 ATATVLVSLVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASSRAS GA GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA Sbjct: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719 Query: 721 LRCSAPPTEGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCP 780 LRCSA PTE CT KPTL+CSSAVGSWSYSQQRRQRVCSGE PPK DLMAFSPSL P Sbjct: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGP 779 >gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo sapiens] Length = 798 Score = 1209 bits (3128), Expect = 0.0 Identities = 617/763 (80%), Positives = 671/763 (87%) Query: 14 LLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDRED 73 LLL LLLLAAW+ G+GQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFR+ASK R Sbjct: 14 LLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGG 73 Query: 74 LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPLF 133 LLEVNLQNGILFVNSRIDREELC RSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPP+F Sbjct: 74 LLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPVF 133 Query: 134 PVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIG 193 P ++ + I ESR DS FPLEGASDAD+G N++LTY+LS +EYF L+ + + K +G Sbjct: 134 PATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKGLG 193 Query: 194 LLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFE 253 L+L+KSLDREEAP L LTATDGGKPELTGTVQLL+TVLD NDNAP F+++ Y+VR+ E Sbjct: 194 LILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRLLE 253 Query: 254 NADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQE 313 N NGT VI+LNASD DEG NG I YSF++ ++ V F ID TG+I+++G +DFE+ Sbjct: 254 NVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFEES 313 Query: 314 NLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALIS 373 Y+I+++ DKG P++GHC V+V + D NDNVP++ SLSLP+REDA GTVIALIS Sbjct: 314 KSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTVIALIS 373 Query: 374 VNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433 V+D D G NG V CSLT HVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP Sbjct: 374 VSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433 Query: 434 SLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYS 493 SLWATAS+SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQENALVSYS Sbjct: 434 SLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS 493 Query: 494 LVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQV 553 LVERRVGERALSSY+SVHAESGKVYALQPLDHEELELLQFQV+ARDAGVPPLGSNVTLQV Sbjct: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGSNVTLQV 553 Query: 554 FVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSYELQP 613 FVLDENDNAPALLAPR GGTGGAVSELVP S+G G VVAKVRAVDADSGYNAWLSYELQP Sbjct: 554 FVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWLSYELQP 613 Query: 614 PASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESG 673 AR PFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEPALTATATVLVSLVESG Sbjct: 614 GTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLVSLVESG 673 Query: 674 QAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACT 733 QAPKASSRA VGA GP+AALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA PTEGAC Sbjct: 674 QAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTEGACA 733 Query: 734 ADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSL 776 KPTLVCSSAVGSWSYSQQRR RVCSGEGPPK DLMAFSPSL Sbjct: 734 PGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSL 776 >gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo sapiens] Length = 844 Score = 1206 bits (3120), Expect = 0.0 Identities = 627/790 (79%), Positives = 675/790 (85%), Gaps = 1/790 (0%) Query: 9 LGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMAS 68 LG QCLLL LLLLAAW+VGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLFR+AS Sbjct: 8 LGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVAS 67 Query: 69 KDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDIND 128 K DLLEVNLQNGILFVNSRIDREELCGRS ECSIHLEVIVDRPLQVFHVDVEV+DIND Sbjct: 68 KRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDIND 127 Query: 129 NPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDD 188 NPP F V EQ++ I ESRL DS FPLEGASDADVG N++LTYKLS +EYF LD+ D Sbjct: 128 NPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDK 187 Query: 189 NKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248 +K L+L+K LDREE P L LTATDGGKPE TG+V LL+ VLD NDNAP F++ YE Sbjct: 188 DKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYE 247 Query: 249 VRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNL 308 V+++EN N T VIRLNASD DEG N + YSF+SLV + F I+ TGEI + + Sbjct: 248 VKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAI 307 Query: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368 DFE N Y+I +D TDKG+PPM GHCTVLV +LD+NDN PE+ +TSLSLPV+EDAQ GTV Sbjct: 308 DFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTV 367 Query: 369 IALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTAR 428 IALISV+D DSGANGQV CSLTPHVPFKLVST+KNYYSLVLDSALDRE VSAYELVVTAR Sbjct: 368 IALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTAR 427 Query: 429 DGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488 DGGSP LWATAS+SVEVAD+NDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQENA Sbjct: 428 DGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENA 487 Query: 489 LVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548 LVSYSLVERR+GER+LSSY+SVHAESGKVYALQPLDHEELELLQFQVSARD GVPPLGSN Sbjct: 488 LVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSN 547 Query: 549 VTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLS 608 +TLQVFVLDENDNAPALLA G GGAVSELV RS+ AG VVAKVRAVDADSGYNAWLS Sbjct: 548 LTLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLS 607 Query: 609 YELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS 668 YELQ A AR PFRVGLYTGEISTTR LDE DSPR RLLVLVKDHGEP+LTATATVLVS Sbjct: 608 YELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVS 667 Query: 669 LVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728 LVE QAPKASSRASVG A PE ALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA PT Sbjct: 668 LVEGSQAPKASSRASVGVA-PEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPT 726 Query: 729 EGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAEN 788 EGAC KPTLVCSSAVGSWSYSQQRRQRVCSGEG PK DLMAFSPSL PCP++ E+ Sbjct: 727 EGACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCPMVDVDGED 786 Query: 789 QDLNEDHDAK 798 Q + DH K Sbjct: 787 QSIGGDHSRK 796 >gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo sapiens] Length = 807 Score = 1204 bits (3114), Expect = 0.0 Identities = 617/794 (77%), Positives = 682/794 (85%) Query: 1 MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 MVF+ LG + LLL LLLLAAW+VGSGQLHYS+PEEAKHGTFVGR+AQDLGLELAELV Sbjct: 1 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60 Query: 61 PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLFR+ASK DLLEVNLQNGILFVNSRIDREELC SAECSIHLE+I DRPLQVFHV+ Sbjct: 61 PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120 Query: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180 V+V+DINDNPP+F EQ + I ESRL +S FP+EGA+DAD+G+N++LTY LS S+YF L Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180 Query: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 DV+ + + +K + L L+K LDREE P +L LTATDGGKPEL GTV+LL+TVLDVNDNAP Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240 Query: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300 F+Q+ Y V + E NGT V LNASD DEG NG + +SF+S ++ + + F +D ++G Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300 Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 EI + LD+E+ Y+I + A DKG PPM+ HC VLV++LD NDN PE+A+TSL LP+R Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360 Query: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 EDA TVIALI+V+D DSGANGQV CSL PHVPFKLVSTFKNYYSLVLDSALDRES+S Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420 Query: 421 YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATA +SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERRVGERALS+Y+SVHAESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGT GAVSELVPR +GAG VVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQP A AR PFRVGLYTGEISTTRVLDEAD R+RLLVLVKDHGEPALT Sbjct: 601 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASSRASVG AGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSAPPTEGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCP 780 LRCS PPTEGA KPTLVCSSA+GSWS SQQRRQRVCS EGPPK DLMAFSP LSP Sbjct: 721 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL 780 Query: 781 IMMGKAENQDLNED 794 + E + N D Sbjct: 781 NTSERNEQPEANLD 794 >gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo sapiens] Length = 789 Score = 1200 bits (3105), Expect = 0.0 Identities = 614/771 (79%), Positives = 672/771 (87%) Query: 10 GKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASK 69 G + LLL +++LAAW+ G GQLHYSVPEEAKHG FVGRIAQDLGLELAELVPRLFR K Sbjct: 10 GGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCK 69 Query: 70 DREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDN 129 R DLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIV+RPLQVFHVDVEV+DINDN Sbjct: 70 FRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDN 129 Query: 130 PPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDN 189 PP+FP ++ + I ESR DS FPLEGASDAD+G N++LTY+LS +EYF LDV ++ Sbjct: 130 PPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQV 189 Query: 190 KQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249 K +GL+L+K LDREE P +L LTATDGGKPELTGTVQLL+TVLD NDNAP F+++ Y V Sbjct: 190 KPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTV 249 Query: 250 RIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLD 309 ++ EN GT VI NASD DEG NG I YSF+S V+ + F +D +G I + G++D Sbjct: 250 KLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMD 309 Query: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369 FE+ +KI ++A DKG PP+AGHCTVLV ++D NDN P++ LTSLSLP+ EDAQ GTVI Sbjct: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369 Query: 370 ALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429 LISV D D G NGQV CSLTP VPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD Sbjct: 370 TLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429 Query: 430 GGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489 GGSPSLWATAS+SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL Sbjct: 430 GGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNAL 489 Query: 490 VSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 VSYSLVE RVGERALSSY+SVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV Sbjct: 490 VSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 Query: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSY 609 TLQVFVLDENDNAPALLAPRVGGTGGAV ELVPRS+GAG VVAKVRAVDADSGYNAWLSY Sbjct: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609 Query: 610 ELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669 ELQP A+ A PFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEP+LTATATVLVSL Sbjct: 610 ELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSL 669 Query: 670 VESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTE 729 VESGQAPKASSRAS+G AGPE LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAP +E Sbjct: 670 VESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSE 729 Query: 730 GACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCP 780 GAC+ KPTLVCSSAVGSWS+SQQRRQRVCSGEGPPK DLMAFSPSL P Sbjct: 730 GACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP 780 >gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo sapiens] Length = 810 Score = 1199 bits (3101), Expect = 0.0 Identities = 621/793 (78%), Positives = 676/793 (85%), Gaps = 4/793 (0%) Query: 9 LGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMAS 68 LG L L LLLL W+VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV RLFR+AS Sbjct: 9 LGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRVAS 68 Query: 69 KDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDIND 128 K DLLEVNLQNGILFVNSRIDREELCG+SAECSIHLEVIVDRPLQVFHV+VEV+DIND Sbjct: 69 KTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDIND 128 Query: 129 NPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDD 188 NPP+F + EQ++LI ES+ DS FPLEGASDAD+ N++LTY+LS +EYF LD N Sbjct: 129 NPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNGKQ 188 Query: 189 NKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248 K++ L+LKKSLDRE+ P NL LTATDGGKPELTGTV+LLV VLDVNDN P F++SEY+ Sbjct: 189 IKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSEYK 248 Query: 249 VRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNL 308 V + ENA T V++LNA+DRDEG NG ++YS S + F++D+N GE+ + G L Sbjct: 249 VSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVNGTL 307 Query: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368 D+E+ YKI + ATDKG PPMAGHCTV V ILD NDN PE+A+TSLSLPVREDAQ TV Sbjct: 308 DYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPSTV 367 Query: 369 IALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTAR 428 IALISV+D DSG NGQV CSLTPHVPFKLVSTFKNYYSLVLDSALDRE+V AYELVVTAR Sbjct: 368 IALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVTAR 427 Query: 429 DGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488 DGGSPSLWATA +SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA Sbjct: 428 DGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 487 Query: 489 LVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548 LVSYSLVERR+G+RALSSY+SVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL SN Sbjct: 488 LVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLSSN 547 Query: 549 VTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLS 608 VTLQVFVLDENDNAPALLA + G GGAV++LVPRS+GAG VVAKVRAVDADSGYNAWLS Sbjct: 548 VTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNAWLS 607 Query: 609 YELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS 668 YELQP A +R PFRVGLYTGEISTTR LDEADSPRHRLLVLVKDHGEPALTATATVLVS Sbjct: 608 YELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVS 667 Query: 669 LVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728 LVESGQAPKASSR GAA PEAALVDVNVYLIIAIC VSSLLVLTLLLYTAL SA PT Sbjct: 668 LVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSATPT 727 Query: 729 EGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAEN 788 EGAC KPTLVCS AVGSWSYSQQRRQRVCS EGPPK DLMAFSPSL P+ + K E Sbjct: 728 EGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSL---PLGLNKEEE 784 Query: 789 QDLNEDHDAKPRQ 801 + E P Q Sbjct: 785 GERQEPGSNHPGQ 797 >gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo sapiens] Length = 824 Score = 1197 bits (3098), Expect = 0.0 Identities = 615/779 (78%), Positives = 675/779 (86%), Gaps = 3/779 (0%) Query: 15 LLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDREDL 74 LL LLLLAAW+VGSGQL YSVPEEAKHGTFVGRIAQDLGLEL ELVPRLFR+ASK DL Sbjct: 15 LLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDL 74 Query: 75 LEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPLFP 134 LEVNLQNGILFVNSRIDREELCGRSAECSIH+EVIVDRPLQVFHV+VEV+DINDNPP+FP Sbjct: 75 LEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDNPPIFP 134 Query: 135 VEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIGL 194 + + + ESRL DS FPLEGASDAD+G N++L+YKLSSSE+F LD++ N + ++ + L Sbjct: 135 MTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELSESLSL 194 Query: 195 LLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFEN 254 +L KSLDREE NL L ATDGGKPELTGTVQ+L+ VLDVNDN PTF QS Y+V++ EN Sbjct: 195 VLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLEN 254 Query: 255 ADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQEN 314 NGT V++LNASD DEG N I YS S V++ + F+ID +GEI +G LD+E+ Sbjct: 255 TANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAK 314 Query: 315 LYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALISV 374 Y+I + ATDKG P M+GHC + ++++D NDN PE+++TSLSLP+ E+A GTVIALI+V Sbjct: 315 SYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITV 374 Query: 375 NDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434 +D DSG NG V CSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS Sbjct: 375 SDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434 Query: 435 LWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSL 494 LWAT S+S+EVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQENALVSYSL Sbjct: 435 LWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494 Query: 495 VERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVF 554 VERRVGERALSSY+SVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLGSNVTLQVF Sbjct: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVF 554 Query: 555 VLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSYELQPP 614 VLDENDNAPALLAPR G GAVSELVP S+GAG VVAKVRAVDADSGYNAWLSYELQ Sbjct: 555 VLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLG 614 Query: 615 ASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674 SAR PFRVGLYTGEISTTR LDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ Sbjct: 615 TGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674 Query: 675 APKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACTA 734 APKASSRA VGAAG EA LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS PPTEGA Sbjct: 675 APKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTEGARAP 734 Query: 735 DKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAENQDLNE 793 KPTLVCSSAVGSWSYSQQRRQRVCSGE PPK DLMAFSPSLS P AE + L+E Sbjct: 735 GKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP---DSAEEKQLSE 790 >gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens] Length = 842 Score = 1192 bits (3083), Expect = 0.0 Identities = 607/768 (79%), Positives = 668/768 (86%) Query: 12 QCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDR 71 Q LLL LL+LA W VGSGQLHYSVPEEA+HGTFVGRIAQDLGLELAELVPRLF++ SK R Sbjct: 12 QPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGR 71 Query: 72 EDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPP 131 DLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEV+DINDNPP Sbjct: 72 GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPP 131 Query: 132 LFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQ 191 +FP ++ + I ESR DS FPLEGASDAD+G N++LTY+LS +EYF LDV ++ K Sbjct: 132 VFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKP 191 Query: 192 IGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRI 251 +GL+L+K LDREE P +L LTATDGGKPELTGTVQLL+TVLD NDNAP F+++ Y V++ Sbjct: 192 LGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKL 251 Query: 252 FENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFE 311 EN GT VI NASD DEG NG I YSF+S V+ + F +D +G I + G++DFE Sbjct: 252 PENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFE 311 Query: 312 QENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIAL 371 + +KI ++A DKG PP+AGHCT+LV ++D NDN P++ + +LS+PV+EDAQ GTVIAL Sbjct: 312 ESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIAL 371 Query: 372 ISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG 431 ISV DLD+ ANGQV CSLTPHVPFKLVST+KNYYSLVLD ALDRESVSAYELVVTARDGG Sbjct: 372 ISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGG 431 Query: 432 SPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVS 491 SPSLWATA +SVEVAD+NDNAPAFAQ EYTVFVKENNPPGCHIFTVSARDADAQENALVS Sbjct: 432 SPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVS 491 Query: 492 YSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL 551 YSLVERR+GER+LSSY+SVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL Sbjct: 492 YSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL 551 Query: 552 QVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSYEL 611 QVFVLDENDNAPALL PR+ GT GAVSE+V RS+GAG VV KVRAVDADSGYNAWLSYEL Sbjct: 552 QVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLSYEL 611 Query: 612 QPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVE 671 QP +SA PFRVGLYTGEISTTR LDE D+PR RLLVLVKDHGEPALTATATVLVSLVE Sbjct: 612 QPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVSLVE 671 Query: 672 SGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGA 731 SGQAPK+SSRASVGA GPE LVDVNVYLIIAICAVSSLLVLTLLLYT LRCSA PTEG Sbjct: 672 SGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMPTEGE 731 Query: 732 CTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPC 779 C KPTLVCSSAVGSWSYSQQRRQRVCSGEG K DLMAFSP LSPC Sbjct: 732 CAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPC 779 >gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo sapiens] Length = 792 Score = 1182 bits (3057), Expect = 0.0 Identities = 612/767 (79%), Positives = 659/767 (85%) Query: 10 GKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASK 69 G Q LLL LLLLAAW+VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFR+ASK Sbjct: 10 GSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69 Query: 70 DREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDN 129 DLLEVNLQNGILFVNSRIDRE+LCGRSAECSIHLEVIVDRPLQVFHVDVEV+DINDN Sbjct: 70 RHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDN 129 Query: 130 PPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDN 189 PP+F EQ+V + ES DS FPLEGASDAD+G NS+LTY LS +E F L +K D + Sbjct: 130 PPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDKS 189 Query: 190 KQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249 L+L+K LDRE+ P NL L DGGKPELTG+VQ+ +TVLDVNDN P F++ Y+V Sbjct: 190 ILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYKV 249 Query: 250 RIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLD 309 + EN N T VI+LNASD DEG NG ISY ++ FSI+ +TGEI I G LD Sbjct: 250 VLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGELD 309 Query: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369 FE+ N Y+I ++A DKG P MAGH VLV +LD NDNVPE+ +TSLSLPV+EDAQ GTVI Sbjct: 310 FEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTVI 369 Query: 370 ALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429 ALISV+D DSGANGQV CSLTPHVPFKLVST+KNYYSLVLDSALDRESVSAYELVVTARD Sbjct: 370 ALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARD 429 Query: 430 GGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489 GGSPSLWATA +SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL Sbjct: 430 GGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNAL 489 Query: 490 VSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 VSYSLVERRVGE ALSSY+SVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV Sbjct: 490 VSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 Query: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSY 609 TLQVFVLDENDNAPALLA G GGAVSELVPRS+GAG VVAKVRAVDADSGYNAWLSY Sbjct: 550 TLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609 Query: 610 ELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669 ELQP A A PF VGLYTGEISTTR+LDEAD+PRHRLLVLVKDHGEPALT+TATVLVSL Sbjct: 610 ELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLVSL 669 Query: 670 VESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTE 729 VE+GQAPK SSRASVGA PEAALVD+NVYLIIAICAVSSLLVLTLLLYTALRCSAPPT Sbjct: 670 VENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPPTV 729 Query: 730 GACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSL 776 C KPTLVCSSAVGSWSYSQQRRQRVCS E PPK DLMAFSPSL Sbjct: 730 SRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776 >gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo sapiens] Length = 686 Score = 1050 bits (2716), Expect = 0.0 Identities = 534/534 (100%), Positives = 534/534 (100%) Query: 1 MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD Sbjct: 61 PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 Query: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180 Query: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP Sbjct: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 Query: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG Sbjct: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300 Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 Query: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQ 534 DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQ Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQ 534 Score = 344 bits (883), Expect = 2e-94 Identities = 241/578 (41%), Positives = 296/578 (51%), Gaps = 78/578 (13%) Query: 441 LSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVG 500 + VEV D+NDN P F E V + E+ P A DAD N++++Y L Sbjct: 119 VDVEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEY- 177 Query: 501 ERALSSYISVHAESGKVYAL---QPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLD 557 + ++++ K L + LD EE ++A D G P L V L V VLD Sbjct: 178 ---FGLDVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLD 234 Query: 558 EN-------------------DNAPALL----APRVGGTGGAVSELVPRSLGAGQVVAKV 594 N DN ++ + R G GA+S SL A V+ Sbjct: 235 VNDNAPTFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSF-NSLVAAMVIDHF 293 Query: 595 RAVDADSG---------YNAWLSYELQPPASSARFPFRVGLYTGEISTTRVLDEADS-PR 644 ++D ++G + Y++ A+ P G T + R+LD+ D+ P Sbjct: 294 -SIDRNTGEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLV---RILDKNDNVPE 349 Query: 645 HRLLVLVKDHGEPALTATATVLVSLVESGQAPKASSRASVGAAGP-EAALVDVNVYLIIA 703 L L E A T L+S+ + S+ P + N Y ++ Sbjct: 350 IALTSLSLPVREDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVL 409 Query: 704 ICAVSSLLVLTLLLYTALRCSAPPTEGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEG 763 A+ V L R P+ A TA V + +++Q Sbjct: 410 DSALDRESVSAYELVVTARDGGSPSLWA-TASLSVEVADMNDNAPAFAQPEYTVFVKENN 468 Query: 764 PPKMDLMAFSP--------SLSPCPIMMGKAENQDLNE-----------------DHDA- 797 PP + S +L ++ + + L+ DH+ Sbjct: 469 PPGCHIFTVSARDADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEEL 528 Query: 798 -----KPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAG 852 +PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAG Sbjct: 529 ELLQFQPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAG 588 Query: 853 EVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSD 912 EVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSD Sbjct: 589 EVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSD 648 Query: 913 FITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 FITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 649 FITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 686 Score = 162 bits (411), Expect = 1e-39 Identities = 115/386 (29%), Positives = 186/386 (48%), Gaps = 16/386 (4%) Query: 230 VTVLDVNDNAPTFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSL-VAAM 288 V V D+NDN P F E V I+E+ + ASD D G+N ++Y +S + Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180 Query: 289 VIDHFSIDRNTGEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVP 348 + S D ++++ +LD E+ + + + ATD G P + G +LV +LD NDN P Sbjct: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 Query: 349 EIALTSLSLPVREDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTF---KNYY 405 + + + E+A GT + ++ +D D GANG ++ S V ++ F +N Sbjct: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300 Query: 406 SLVLDSALDRESVSAYELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVK 465 +V+ LD E + Y++++ A D G P + ++ V + D NDN P A ++ V+ Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 Query: 466 ENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDH 525 E+ G I +S D D+ N V+ SL V + +S++ + ++ + LD Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPH-VPFKLVSTFKNYYS----LVLDSALDR 415 Query: 526 EELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSL 585 E + + V+ARD G P L + +L V V D NDNAPA P + V + Sbjct: 416 ESVSAYELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPE-------YTVFVKENN 468 Query: 586 GAGQVVAKVRAVDADSGYNAWLSYEL 611 G + V A DAD+ NA +SY L Sbjct: 469 PPGCHIFTVSARDADAQENALVSYSL 494 Score = 143 bits (360), Expect = 9e-34 Identities = 104/341 (30%), Positives = 156/341 (45%), Gaps = 21/341 (6%) Query: 338 VRILDKNDNVPEIALTSLSLPVREDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPF-- 395 V + D NDN P + + + E +V L +D D G+N + L+ F Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180 Query: 396 --KLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWATASLSVEVADMNDNAP 453 K+ S L+L +LDRE A+ L +TA DGG P L T L V V D+NDNAP Sbjct: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 Query: 454 AFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERALSSYISVHAE 513 F Q EY V + EN G + ++A D D N +SYS + + + S+ Sbjct: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSF--NSLVAAMVIDHFSIDRN 298 Query: 514 SGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRVGGT 573 +G++ LD E+ L + + A D G PP+ + T+ V +LD+NDN P + Sbjct: 299 TGEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALT----- 353 Query: 574 GGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSYELQPPASSARFPFR-VGLYTGEIS 632 ++S V G V+A + D DSG N ++ L P PF+ V + S Sbjct: 354 --SLSLPVREDAQFGTVIALISVNDLDSGANGQVNCSLTP-----HVPFKLVSTFKNYYS 406 Query: 633 TT--RVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVE 671 LD + L+V +D G P+L ATA++ V + + Sbjct: 407 LVLDSALDRESVSAYELVVTARDGGSPSLWATASLSVEVAD 447 >gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo sapiens] Length = 685 Score = 795 bits (2054), Expect = 0.0 Identities = 408/526 (77%), Positives = 449/526 (85%) Query: 9 LGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMAS 68 LG QCLLL LLLLAAW+VGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLFR+AS Sbjct: 8 LGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVAS 67 Query: 69 KDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDIND 128 K DLLEVNLQNGILFVNSRIDREELCGRS ECSIHLEVIVDRPLQVFHVDVEV+DIND Sbjct: 68 KRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDIND 127 Query: 129 NPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDD 188 NPP F V EQ++ I ESRL DS FPLEGASDADVG N++LTYKLS +EYF LD+ D Sbjct: 128 NPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDK 187 Query: 189 NKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248 +K L+L+K LDREE P L LTATDGGKPE TG+V LL+ VLD NDNAP F++ YE Sbjct: 188 DKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYE 247 Query: 249 VRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNL 308 V+++EN N T VIRLNASD DEG N + YSF+SLV + F I+ TGEI + + Sbjct: 248 VKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAI 307 Query: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368 DFE N Y+I +D TDKG+PPM GHCTVLV +LD+NDN PE+ +TSLSLPV+EDAQ GTV Sbjct: 308 DFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTV 367 Query: 369 IALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTAR 428 IALISV+D DSGANGQV CSLTPHVPFKLVST+KNYYSLVLDSALDRE VSAYELVVTAR Sbjct: 368 IALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTAR 427 Query: 429 DGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488 DGGSP LWATAS+SVEVAD+NDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQENA Sbjct: 428 DGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENA 487 Query: 489 LVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQ 534 LVSYSLVERR+GER+LSSY+SVHAESGKVYALQPLDHEELELLQFQ Sbjct: 488 LVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQ 533 Score = 409 bits (1051), Expect = e-114 Identities = 271/622 (43%), Positives = 340/622 (54%), Gaps = 65/622 (10%) Query: 338 VRILDKNDNVPEIALTSLSLPVREDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKL 397 V + D NDN P ++T L + E + L +D D G N + L+P+ F L Sbjct: 120 VEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVL 179 Query: 398 VSTFKN----YYSLVLDSALDRESVSAYELVVTARDGGSPSLWATASLSVEVADMNDNAP 453 K + LVL LDRE +L++TA DGG P + SL + V D NDNAP Sbjct: 180 DIINKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAP 239 Query: 454 AFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERALSSYISVHAE 513 F +P Y V + EN + ++A D+D N + YS + + ++ Sbjct: 240 IFDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSS--LVPPTIRRKFWINER 297 Query: 514 SGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRVGGT 573 +G++ +D E+ + V D G PP+ + T+ V +LDENDN+P ++ Sbjct: 298 TGEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVT----- 352 Query: 574 GGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSYELQPPASSARFPFRVGLYTGEIST 633 ++S V G V+A + D DSG N ++ L P PF++ +ST Sbjct: 353 --SLSLPVKEDAQVGTVIALISVSDHDSGANGQVTCSLTP-----HVPFKL------VST 399 Query: 634 TRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQAPKASSRASVGAAGPEAAL 693 + LV D +A LV G +P + ASV E A Sbjct: 400 YK----------NYYSLVLDSALDRERVSAYELVVTARDGGSPPLWATASVSV---EVAD 446 Query: 694 VDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPP-----TEGACTADKPTLVCSSAVGSW 748 V+ N A S V ++ + PP T A AD +A+ S+ Sbjct: 447 VNDNAPAF----AQSEYTVF-------VKENNPPGCHIFTVSAWDADAQ----ENALVSY 491 Query: 749 SYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAENQDLNEDHDAKPRQPNPDWRY 808 S ++R G + + S + ++++L E +PRQPNPDWRY Sbjct: 492 SLVERRL-------GERSLSSYVSVHAESGKVYALQPLDHEEL-ELLQFQPRQPNPDWRY 543 Query: 809 SASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWT 868 SASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWT Sbjct: 544 SASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWT 603 Query: 869 FKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKK 928 FKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKK Sbjct: 604 FKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKK 663 Query: 929 KKGNKTQEKKEKGNSTTDNSDQ 950 KKGNKTQEKKEKGNSTTDNSDQ Sbjct: 664 KKGNKTQEKKEKGNSTTDNSDQ 685 Score = 144 bits (364), Expect = 3e-34 Identities = 114/387 (29%), Positives = 183/387 (47%), Gaps = 18/387 (4%) Query: 230 VTVLDVNDNAPTFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSF--NSLVAA 287 V V D+NDN P F +E ++ I E+ + ASD D G N ++Y N Sbjct: 120 VEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVL 179 Query: 288 MVIDHFSIDRNTGEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNV 347 +I+ D+ +V+R LD E+ K+L+ ATD G P G ++L+ +LD NDN Sbjct: 180 DIINKKDKDKFP-VLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNA 238 Query: 348 PEIALTSLSLPVREDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTF---KNY 404 P + + E+ T++ ++ +D D G N ++ S + VP + F + Sbjct: 239 PIFDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERT 298 Query: 405 YSLVLDSALDRESVSAYELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFV 464 + ++ A+D E + YE+ V D G+P + ++ VE+ D NDN+P ++ V Sbjct: 299 GEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPV 358 Query: 465 KENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLD 524 KE+ G I +S D D+ N V+ SL V + +S+Y + ++ + LD Sbjct: 359 KEDAQVGTVIALISVSDHDSGANGQVTCSLTPH-VPFKLVSTYKNYYS----LVLDSALD 413 Query: 525 HEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRS 584 E + + V+ARD G PPL + ++ V V D NDNAPA + V + Sbjct: 414 RERVSAYELVVTARDGGSPPLWATASVSVEVADVNDNAPAF-------AQSEYTVFVKEN 466 Query: 585 LGAGQVVAKVRAVDADSGYNAWLSYEL 611 G + V A DAD+ NA +SY L Sbjct: 467 NPPGCHIFTVSAWDADAQENALVSYSL 493 Score = 91.3 bits (225), Expect = 4e-18 Identities = 84/273 (30%), Positives = 118/273 (43%), Gaps = 21/273 (7%) Query: 441 LSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVG 500 + VEV D+NDN P F+ E + + E+ A DAD ENAL++Y L Sbjct: 118 VDVEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYF 177 Query: 501 ERALSSYISVHAESGKVYALQPL-DHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDEN 559 L + V L+ L D EE L+ ++A D G P +V+L + VLD N Sbjct: 178 --VLDIINKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDAN 235 Query: 560 DNAPALLAPRVGGTGGAVSELVPRSLGAGQ-VVAKVRAVDADSGYNAWLSYE---LQPPA 615 DNAP P V E+ Q +V ++ A D+D G N + Y L PP Sbjct: 236 DNAPIFDRP--------VYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPP- 286 Query: 616 SSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQA 675 + R F + TGEI +D DS + + V V D G P + TVLV L++ Sbjct: 287 -TIRRKFWINERTGEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDN 345 Query: 676 PKASSRASVGAAGPEAALVDVNVYLIIAICAVS 708 S+ E D V +IA+ +VS Sbjct: 346 SPEVIVTSLSLPVKE----DAQVGTVIALISVS 374 >gi|14165402 protocadherin alpha 1 isoform 3 precursor [Homo sapiens] Length = 686 Score = 780 bits (2014), Expect = 0.0 Identities = 392/534 (73%), Positives = 452/534 (84%) Query: 1 MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 MVF+ LG + LLL LLLLAAW+VGSGQLHYS+PEEAKHGTFVGR+AQDLGLELAELV Sbjct: 1 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60 Query: 61 PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLFR+ASK DLLEVNLQNGILFVNSRIDREELC SAECSIHLE+I DRPLQVFHV+ Sbjct: 61 PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120 Query: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180 V+V+DINDNPP+F EQ + I ESRL +S FP+EGA+DAD+G+N++LTY LS S+YF L Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180 Query: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 DV+ + + +K + L L+K LDREE P +L LTATDGGKPEL GTV+LL+TVLDVNDNAP Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240 Query: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300 F+Q+ Y V + E NGT V LNASD DEG NG + +SF+S ++ + + F +D ++G Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300 Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 EI + LD+E+ Y+I + A DKG PPM+ HC VLV++LD NDN PE+A+TSL LP+R Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360 Query: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 EDA TVIALI+V+D DSGANGQV CSL PHVPFKLVSTFKNYYSLVLDSALDRES+S Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420 Query: 421 YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATA +SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQ 534 DADAQENALVSYSLVERRVGERALS+Y+SVHAESGKVYALQPLDHEELELLQFQ Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQ 534 Score = 319 bits (817), Expect = 9e-87 Identities = 152/153 (99%), Positives = 153/153 (100%) Query: 798 KPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPP 857 +PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPP Sbjct: 534 QPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPP 593 Query: 858 VGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFG 917 VGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFG Sbjct: 594 VGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFG 653 Query: 918 KKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 KKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 654 KKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 686 Score = 150 bits (379), Expect = 5e-36 Identities = 118/392 (30%), Positives = 183/392 (46%), Gaps = 28/392 (7%) Query: 230 VTVLDVNDNAPTFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMV 289 V V D+NDN P F E + I E+ + A+D D GAN ++Y+ + Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPS----- 175 Query: 290 IDHFSIDRNTGE-------IVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILD 342 D+FS+D + + +R LD E+ +L+ ATD G P + G +L+ +LD Sbjct: 176 -DYFSLDVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLD 234 Query: 343 KNDNVPEIALTSLSLPVREDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFK 402 NDN P + + E GT++ ++ +D D G NG+V S + + FK Sbjct: 235 VNDNAPLFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFK 294 Query: 403 NYYS---LVLDSALDRESVSAYELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPE 459 S + L LD E +YE+ V A D GSP + + V+V D+NDNAP A Sbjct: 295 VDSSSGEIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTS 354 Query: 460 YTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERALSSYISVHAESGKVYA 519 + ++E+ P I ++ D D+ N V+ SL+ V + +S++ + ++ + Sbjct: 355 LYLPIREDAPLSTVIALITVSDRDSGANGQVTCSLMPH-VPFKLVSTFKNYYS----LVL 409 Query: 520 LQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSE 579 LD E L + + V+ARD G P L + + V V D NDNAPA P + Sbjct: 410 DSALDRESLSVYELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPE-------YTV 462 Query: 580 LVPRSLGAGQVVAKVRAVDADSGYNAWLSYEL 611 V + G + V A DAD+ NA +SY L Sbjct: 463 FVKENNPPGCHIFTVSARDADAQENALVSYSL 494 Score = 136 bits (343), Expect = 8e-32 Identities = 110/349 (31%), Positives = 157/349 (44%), Gaps = 33/349 (9%) Query: 336 VLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPF 395 V V++ D NDN P + + E + + D D GAN + +L+P F Sbjct: 119 VEVKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYF 178 Query: 396 KLVSTFKNYYS----LVLDSALDRESVSAYELVVTARDGGSPSLWATASLSVEVADMNDN 451 L + S L L LDRE L++TA DGG P L T L + V D+NDN Sbjct: 179 SLDVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDN 238 Query: 452 APAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSL---VERRVGERALSSYI 508 AP F Q Y V + E G + T++A DAD N V +S + R + E+ Sbjct: 239 APLFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEK-----F 293 Query: 509 SVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAP 568 V + SG++ + LD+EE + + QV A D G PP+ ++ + V VLD NDNAP L Sbjct: 294 KVDSSSGEIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPEL--- 350 Query: 569 RVGGTGGAVSEL---VPRSLGAGQVVAKVRAVDADSGYNAWLSYELQPPASSARFPFR-V 624 AV+ L + V+A + D DSG N ++ L P PF+ V Sbjct: 351 -------AVTSLYLPIREDAPLSTVIALITVSDRDSGANGQVTCSLMP-----HVPFKLV 398 Query: 625 GLYTGEISTT--RVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVE 671 + S LD + L+V +D G P+L ATA V V + + Sbjct: 399 STFKNYYSLVLDSALDRESLSVYELVVTARDGGSPSLWATARVSVEVAD 447 >gi|14277675 protocadherin gamma subfamily C, 3 isoform 1 precursor [Homo sapiens] Length = 934 Score = 618 bits (1593), Expect = e-177 Identities = 366/936 (39%), Positives = 531/936 (56%), Gaps = 46/936 (4%) Query: 18 LLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDREDLLEV 77 LLLL A S +HY +PEE + G VG + +LGL+L L R FR+ S EV Sbjct: 20 LLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFEV 79 Query: 78 NLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPLFPVEE 137 N + G +FVN R+DREELCG C++ LE++V+ PL++F V+V ++DINDN P FP +E Sbjct: 80 NRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQE 139 Query: 138 QRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIGLLLK 197 ++ I E+ P + FPLE A D DVGSNS+ TY+LS +EYF L V+ D K L+L+ Sbjct: 140 MKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVLE 199 Query: 198 KSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFENADN 257 ++LDRE P+ L LTA DGG P L+ ++ + + VLD NDNAP F QS Y R+ E+A + Sbjct: 200 RALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAPS 259 Query: 258 GTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQENLYK 317 GT V+++ A+D DEG NG I YSF S A V F++D TG + I+G LDFE L++ Sbjct: 260 GTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLHE 319 Query: 318 ILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALISVNDL 377 I I A DKG P HC VLV ++D NDN PEI +TS+ PV EDA GTVIAL+SV DL Sbjct: 320 IYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTDL 379 Query: 378 DSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWA 437 D+G NG V C + P +PF L S+ KNY++L + LDRE+V Y L +TARD G+PSL A Sbjct: 380 DAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLSA 439 Query: 438 TASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVER 497 + V+V+D+NDN P +Q Y V+++ENN PG I +S D DA +NA +S+ L+E+ Sbjct: 440 LTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLEQ 499 Query: 498 RVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLD 557 + Y +++ ++G V +L PLD+E+ + D G P L +N+++ +FV D Sbjct: 500 GAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVTD 559 Query: 558 ENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSYELQPPASS 617 NDNAP +L PR GG+ E++PR AG +V++V DAD+G+NAWLSY L S Sbjct: 560 RNDNAPQVLYPRPGGSS---VEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLL--GSP 614 Query: 618 ARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQAPK 677 + F +GL+TG+IST R + + DSPR L VL+KD+GEP+L+ TAT+ VS+ E +P+ Sbjct: 615 NQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTE--DSPE 672 Query: 678 ASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLT---LLLYTALRCS------APPT 728 A + G+A P ++ YL++++ VS V+T ++++ + P Sbjct: 673 ARAEFPSGSA-PREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYRAPV 731 Query: 729 EGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAEN 788 P+L + G Q + + L+ + SP + Sbjct: 732 SSLYRTPGPSLHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQNTLRS 791 Query: 789 QD------LNEDHDAKPRQ---PNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQW 839 D + A P Q PN DWR+S + R G S + ++ G P+ Q+ Sbjct: 792 CDPVFYRQVLGAESAPPGQQAPPNTDWRFSQAQRPGTSGSQNGDDTGT------WPNNQF 845 Query: 840 PT-------VSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPG 892 T ++SA+ EA + S +G G + + +YGP Q P + IPG Sbjct: 846 DTEMLQAMILASAS---EAADGSSTLGGGAGTMGLSARYGPQFTLQHVP-DYRQNVYIPG 901 Query: 893 SPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKK 928 S A ++ + K+ G K+++ KK+KK Sbjct: 902 SNATLT---NAAGKRDGKAPAGGNGNKKKSGKKEKK 934 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.314 0.132 0.381 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 39,145,080 Number of Sequences: 37866 Number of extensions: 1974761 Number of successful extensions: 14481 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 213 Number of HSP's successfully gapped in prelim test: 59 Number of HSP's that attempted gapping in prelim test: 6787 Number of HSP's gapped (non-prelim): 1171 length of query: 950 length of database: 18,247,518 effective HSP length: 112 effective length of query: 838 effective length of database: 14,006,526 effective search space: 11737468788 effective search space used: 11737468788 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.