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Search of human proteins with 9256580
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo
sapiens]
(950 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo sapi... 1889 0.0
gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo sap... 1575 0.0
gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens] 1550 0.0
gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens] 1541 0.0
gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens] 1532 0.0
gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens] 1524 0.0
gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo sapi... 1521 0.0
gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens] 1518 0.0
gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo sapi... 1513 0.0
gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens] 1512 0.0
gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens] 1511 0.0
gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens] 1505 0.0
gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo sapi... 1496 0.0
gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo sapi... 1482 0.0
gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo sapi... 1237 0.0
gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo sapi... 1229 0.0
gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo sapi... 1222 0.0
gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo sapi... 1216 0.0
gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo sap... 1211 0.0
gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo sapi... 1207 0.0
gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapi... 1207 0.0
gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo sapi... 1201 0.0
gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens] 1200 0.0
gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo sapi... 1199 0.0
gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo sap... 1189 0.0
gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo sap... 1175 0.0
gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo sapi... 798 0.0
gi|14165402 protocadherin alpha 1 isoform 3 precursor [Homo sapi... 792 0.0
gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo sap... 771 0.0
gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precurs... 625 e-179
>gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo
sapiens]
Length = 950
Score = 1889 bits (4893), Expect = 0.0
Identities = 950/950 (100%), Positives = 950/950 (100%)
Query: 1 MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV
Sbjct: 1 MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120
PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE
Sbjct: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120
Query: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180
VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL
Sbjct: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180
Query: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240
DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP
Sbjct: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240
Query: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300
EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG
Sbjct: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300
Query: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360
EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR
Sbjct: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360
Query: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420
EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA
Sbjct: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420
Query: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480
YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ
Sbjct: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480
Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540
DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS
Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540
Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600
GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600
Query: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660
SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660
Query: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
Query: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL 780
LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL
Sbjct: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL 780
Query: 781 GSAEGTGQREEDSECLKEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840
GSAEGTGQREEDSECLKEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP
Sbjct: 781 GSAEGTGQREEDSECLKEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840
Query: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900
TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR
Sbjct: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900
Query: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950
QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950
>gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo
sapiens]
Length = 807
Score = 1575 bits (4077), Expect = 0.0
Identities = 798/798 (100%), Positives = 798/798 (100%)
Query: 1 MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV
Sbjct: 1 MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120
PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE
Sbjct: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120
Query: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180
VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL
Sbjct: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180
Query: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240
DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP
Sbjct: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240
Query: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300
EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG
Sbjct: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300
Query: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360
EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR
Sbjct: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360
Query: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420
EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA
Sbjct: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420
Query: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480
YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ
Sbjct: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480
Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540
DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS
Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540
Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600
GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600
Query: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660
SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660
Query: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
Query: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL 780
LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL
Sbjct: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL 780
Query: 781 GSAEGTGQREEDSECLKE 798
GSAEGTGQREEDSECLKE
Sbjct: 781 GSAEGTGQREEDSECLKE 798
>gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens]
Length = 950
Score = 1550 bits (4014), Expect = 0.0
Identities = 782/950 (82%), Positives = 846/950 (89%)
Query: 1 MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
ML SW+ P + LLL LL+LAA E GSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV
Sbjct: 1 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60
Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120
PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE
Sbjct: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120
Query: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180
V+V+DINDN P+FP + K + I+ESR P +RF L+GASDADIG NS LTY LD +YFTL
Sbjct: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180
Query: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240
D + + E++ SL LVL+K L+RE+ +H LL+TA DGGKPELTGT QL IT+LDVNDNAP
Sbjct: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240
Query: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300
F +++YKV +LENA NGTLV+ +NATD D+G N DI YSF + ++ F ++P NG
Sbjct: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300
Query: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360
+I KG +DFEE K YEI VEA DKGN PM+ HCT+L+E++D+NDN PE+ I SLSLP+
Sbjct: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360
Query: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420
ED+ S +IALISVSDRDSG NGQVTC+LTPHVPFKLVST+KNYYSLVLDS LDRESVSA
Sbjct: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420
Query: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480
YELVVTARDGGSPSLWATASVSV VADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSA+
Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480
Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540
DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD+
Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540
Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600
GVPPLGSNVTLQVFVLDENDNAPALL P G GG VSEL+PRSVGAGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600
Query: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660
SGYNAWLSYELQ GARIPFRVGLYTGEISTTR LDEVDAP HRLLVLVKDHGEP+LT
Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660
Query: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
ATATVL+SLVESGQAP+ASS+ASAGA GPEAALVDVNVYLI+AICAVSSLLVLTLLLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720
Query: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL 780
LRCSAPPTEG C PGKPTLVCSSA GSWSYSQQR+ RVCSGEG KTDLMAFSPSLPPC
Sbjct: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780
Query: 781 GSAEGTGQREEDSECLKEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840
S + +++ D + +PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP
Sbjct: 781 ISRDREEKQDVDVDLSAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840
Query: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900
TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR
Sbjct: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900
Query: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950
QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950
>gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens]
Length = 947
Score = 1541 bits (3989), Expect = 0.0
Identities = 783/947 (82%), Positives = 836/947 (88%), Gaps = 3/947 (0%)
Query: 4 SWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRL 63
SW G R+LLL LL+LAAWE G+GQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRL
Sbjct: 4 SWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRL 63
Query: 64 FRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKV 123
FRVASK G LLEVNLQNGILFVNSRIDREELC RSAECSIHLEVIVDRPLQVFHV+V+V
Sbjct: 64 FRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEV 123
Query: 124 RDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQ 183
RDINDNPP+FP ++K + IAESRP ++RFPL+GASDADIG N+ LTYRL PN+YF+L+
Sbjct: 124 RDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKP 183
Query: 184 NSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFY 243
E + L L+LRK+LDREE E L+LTA+DGGKPELTGTVQLLIT+LD NDNAP F
Sbjct: 184 PDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFD 243
Query: 244 QSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIR 303
+++YKV +LEN NGTLVIKLNA+D D+G NGDIVYSF + P V F I+P G+I
Sbjct: 244 RTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQII 303
Query: 304 TKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDT 363
KG +DFEE K YEI VE +DKG +P++GHC ++VEV D NDN P++ SLSLPIRED
Sbjct: 304 VKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDA 363
Query: 364 QPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYEL 423
+IALISVSD+D G NG VTC+LT HVPFKLVST+KNYYSLVLDSALDRESVSAYEL
Sbjct: 364 PLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYEL 423
Query: 424 VVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDAD 483
VVTARDGGSPSLWATASVSV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DAD
Sbjct: 424 VVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDAD 483
Query: 484 AQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVP 543
AQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARD+GVP
Sbjct: 484 AQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVP 543
Query: 544 PLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGY 603
PLGSNVTLQVFVLDENDNAPALL P AG GG VSEL+P SVG GHVVAKVRAVDADSGY
Sbjct: 544 PLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGY 603
Query: 604 NAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATA 663
NAWLSYELQ GARIPFRVGLYTGEISTTR LDE DAP HRLLVLVKDHGEPALTATA
Sbjct: 604 NAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATA 663
Query: 664 TVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRC 723
TVL+SLVESGQAP+ASSRA GAVGP+AALVDVNVYLIIAICAVSSLLVLTLLLYTALRC
Sbjct: 664 TVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRC 723
Query: 724 SAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCLGSA 783
SA PTEGACAPGKPTLVCSSA GSWSYSQQRRPRVCSGEGP KTDLMAFSPSLP S
Sbjct: 724 SALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLP---DSR 780
Query: 784 EGTGQREEDSECLKEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVS 843
+ Q + E +PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVS
Sbjct: 781 DREDQLQTTEESFAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVS 840
Query: 844 SATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEP 903
SATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEP
Sbjct: 841 SATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEP 900
Query: 904 TNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950
TNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 901 TNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 947
>gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens]
Length = 950
Score = 1532 bits (3966), Expect = 0.0
Identities = 767/946 (81%), Positives = 839/946 (88%)
Query: 5 WQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLF 64
W+G +LLL LL+LAAW+ GSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLF
Sbjct: 5 WRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLF 64
Query: 65 RVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVR 124
RVASKRH DLLEV+LQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+V+V+
Sbjct: 65 RVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVK 124
Query: 125 DINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQN 184
D+NDNPP+F +++ ++ESR P++RFPL+GASDAD+G NS LTYRL +DYF LD +
Sbjct: 125 DVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNS 184
Query: 185 SLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQ 244
++ + LVLRK+LDRE+ H L LTA+DGGKPELTGTVQLL+T+LDVNDNAP F Q
Sbjct: 185 KNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQ 244
Query: 245 SVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRT 304
S Y+V + ENA NGT VIKLNA+DPD+G NG I YSF V V+ F+I+ N GEI
Sbjct: 245 SEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVI 304
Query: 305 KGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQ 364
+G LDFE++ LY+I ++A DKG+ PMAGHCT+LV +LD NDN PE+ +TSLSLP+RED Q
Sbjct: 305 RGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQ 364
Query: 365 PSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELV 424
+IALISV+D DSG+NGQVTC+L PHVPFKLVST+KNYYSLVLDSALDRE VSAYELV
Sbjct: 365 FGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELV 424
Query: 425 VTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADA 484
VTARDGGSPSLWATAS+SV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA+DADA
Sbjct: 425 VTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADA 484
Query: 485 QENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPP 544
QENALVSYSLVERRVGER+LSSY+SVH ESGKVYALQPLDHEELELLQFQVSARD+GVPP
Sbjct: 485 QENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPP 544
Query: 545 LGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYN 604
LGSNVTLQVFVLDENDNAPALL P G GG S+L+PRSVGAGHVVAKVRAVDADSGYN
Sbjct: 545 LGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYN 604
Query: 605 AWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATAT 664
AWLSYELQ AA RIPFRVGLYTGEISTTR LDE D+P HRLLVLVKDHGEPALTATAT
Sbjct: 605 AWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATAT 664
Query: 665 VLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCS 724
VL+SLVESGQAP+ASSR SAG +GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCS
Sbjct: 665 VLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCS 724
Query: 725 APPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCLGSAE 784
A PTEG C GKPTLVCSSA GSWSYSQQ+ RVCSGEGP KTDLMAFSP LPP LGS +
Sbjct: 725 ALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVD 784
Query: 785 GTGQREEDSECLKEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSS 844
+++ + + +PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSS
Sbjct: 785 VGEEQDLNVDHGLKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSS 844
Query: 845 ATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPT 904
ATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPT
Sbjct: 845 ATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPT 904
Query: 905 NSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950
NSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 905 NSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950
>gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens]
Length = 950
Score = 1524 bits (3945), Expect = 0.0
Identities = 768/940 (81%), Positives = 834/940 (88%), Gaps = 6/940 (0%)
Query: 14 LLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGD 73
LLL LL+LAAW+ GSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFR+ASK D
Sbjct: 14 LLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDRED 73
Query: 74 LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDINDNPPIF 133
LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+V+VRDINDNPP+F
Sbjct: 74 LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPLF 133
Query: 134 PESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLEQMSSLS 193
P ++R++I ESR P++ FPL+GASDAD+G NS LTY+L ++YF LD + + + +
Sbjct: 134 PVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIG 193
Query: 194 LVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVYKVTVLE 253
L+L+K+LDREE H+L LTA+DGGKPELTGTVQLL+T+LDVNDNAP F QS Y+V + E
Sbjct: 194 LLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFE 253
Query: 254 NAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGKLDFEEK 313
NA NGT VI+LNA+D D+G NG I YSF V V+ F+I+ N GEI +G LDFE++
Sbjct: 254 NADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQE 313
Query: 314 KLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPSAIIALIS 373
LY+I ++A DKG+ PMAGHCT+LV +LD NDN PE+ +TSLSLP+RED Q +IALIS
Sbjct: 314 NLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALIS 373
Query: 374 VSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433
V+D DSG+NGQV C+LTPHVPFKLVST+KNYYSLVLDSALDRESVSAYELVVTARDGGSP
Sbjct: 374 VNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433
Query: 434 SLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQENALVSYS 493
SLWATAS+SV VAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA+DADAQENALVSYS
Sbjct: 434 SLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYS 493
Query: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLGSNVTLQV 553
LVERRVGERALSSY+SVHAESGKVYALQPLDHEELELLQFQVSARD+GVPPLGSNVTLQV
Sbjct: 494 LVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQV 553
Query: 554 FVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWLSYELQL 613
FVLDENDNAPALL P G GG VSEL+PRS+GAG VVAKVRAVDADSGYNAWLSYELQ
Sbjct: 554 FVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSYELQP 613
Query: 614 AAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVLLSLVESG 673
A AR PFRVGLYTGEISTTR LDE D+P HRLLVLVKDHGEPALTATATVL+SLVESG
Sbjct: 614 PASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESG 673
Query: 674 QAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACA 733
QAP+ASSRAS GA GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGAC
Sbjct: 674 QAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACT 733
Query: 734 PGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPC---LGSAEGTGQRE 790
KPTLVCSSA GSWSYSQQRR RVCSGEGP K DLMAFSPSL PC +G AE E
Sbjct: 734 ADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAENQDLNE 793
Query: 791 EDSECLKEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPE 850
+ +PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPE
Sbjct: 794 DHD---AKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPE 850
Query: 851 AGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDK 910
AGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDK
Sbjct: 851 AGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDK 910
Query: 911 SDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950
SDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 911 SDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950
>gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo
sapiens]
Length = 949
Score = 1521 bits (3938), Expect = 0.0
Identities = 770/944 (81%), Positives = 839/944 (88%), Gaps = 4/944 (0%)
Query: 7 GGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRV 66
G PR L LWLL+L WE GSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV RLFRV
Sbjct: 10 GTPR---LQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRV 66
Query: 67 ASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDI 126
ASK HGDLLEVNLQNGILFVNSRIDREELCG+SAECSIHLEVIVDRPLQVFHV V+V+DI
Sbjct: 67 ASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDI 126
Query: 127 NDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSL 186
NDNPP+F +++++IAES+ ++RFPL+GASDADI N+ LTYRL N+YF+LD+ +
Sbjct: 127 NDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNG 186
Query: 187 EQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSV 246
+Q+ LSL+L+K+LDRE+ E +LLLTA+DGGKPELTGTV+LL+ +LDVNDN PEF +S
Sbjct: 187 KQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSE 246
Query: 247 YKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKG 306
YKV+++ENA TLV+KLNATD D+G NG++ YS + P + FT++ NNGE+R G
Sbjct: 247 YKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVNG 305
Query: 307 KLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPS 366
LD+EE K Y+I V+A DKG PMAGHCT+ VE+LD NDN+PEV +TSLSLP+RED QPS
Sbjct: 306 TLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPS 365
Query: 367 AIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVT 426
+IALISVSDRDSG NGQVTC+LTPHVPFKLVST+KNYYSLVLDSALDRE+V AYELVVT
Sbjct: 366 TVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVT 425
Query: 427 ARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQE 486
ARDGGSPSLWATA VSV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA+DADAQE
Sbjct: 426 ARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQE 485
Query: 487 NALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLG 546
NALVSYSLVERR+G+RALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD+GVPPL
Sbjct: 486 NALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLS 545
Query: 547 SNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAW 606
SNVTLQVFVLDENDNAPALL AGSAGG V++L+PRSVGAGHVVAKVRAVDADSGYNAW
Sbjct: 546 SNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNAW 605
Query: 607 LSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVL 666
LSYELQ AA G+RIPFRVGLYTGEISTTR LDE D+P HRLLVLVKDHGEPALTATATVL
Sbjct: 606 LSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVL 665
Query: 667 LSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAP 726
+SLVESGQAP+ASSR AGA PEAALVDVNVYLIIAIC VSSLLVLTLLLYTAL SA
Sbjct: 666 VSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSAT 725
Query: 727 PTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCLGSAEGT 786
PTEGACAPGKPTLVCS A GSWSYSQQRR RVCS EGP KTDLMAFSPSLP L E
Sbjct: 726 PTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNKEEEG 785
Query: 787 GQREEDSECLKEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSAT 846
++E S +PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSAT
Sbjct: 786 ERQEPGSNHPGQPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSAT 845
Query: 847 PEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNS 906
PEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNS
Sbjct: 846 PEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNS 905
Query: 907 QIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950
QIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 906 QIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 949
>gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens]
Length = 948
Score = 1518 bits (3931), Expect = 0.0
Identities = 779/950 (82%), Positives = 837/950 (88%), Gaps = 2/950 (0%)
Query: 1 MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
M SS + G LL LL+LAAWE GSGQL YSVPEEAKHGTFVGRIAQDLGLEL ELV
Sbjct: 1 MASSIRRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELV 60
Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120
PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIH+EVIVDRPLQVFHVE
Sbjct: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVE 120
Query: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180
V+V+DINDNPPIFP + K I ESR ++RFPL+GASDADIGVN+ L+Y+L +++F L
Sbjct: 121 VEVKDINDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFL 180
Query: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240
D Q + E SLSLVL K+LDREE E +LLL A+DGGKPELTGTVQ+LI +LDVNDN P
Sbjct: 181 DIQANDELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEP 240
Query: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300
F QSVYKV +LEN NGTLV+KLNA+D D+G N +IVYS V + FTI+P +G
Sbjct: 241 TFAQSVYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISG 300
Query: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360
EIRTKGKLD+EE K YEI V A DKG M+GHC + ++++D+NDN PEV+ITSLSLPI
Sbjct: 301 EIRTKGKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPIS 360
Query: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420
E+ +IALI+VSDRDSG+NG VTC+LTPHVPFKLVST+KNYYSLVLDSALDRESVSA
Sbjct: 361 ENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420
Query: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480
YELVVTARDGGSPSLWAT SVS+ VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA
Sbjct: 421 YELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480
Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540
DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARD+
Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 540
Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600
GVPPLGSNVTLQVFVLDENDNAPALL P AG+A G VSEL+P SVGAGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDAD 600
Query: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660
SGYNAWLSYELQL ARIPFRVGLYTGEISTTR LDE D+P HRLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALT 660
Query: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
ATATVL+SLVESGQAP+ASSRA GA G EA LVDVNVYLIIAICAVSSLLVLT+LLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTA 720
Query: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL 780
LRCS PPTEGA APGKPTLVCSSA GSWSYSQQRR RVCSGE P KTDLMAFSPSL
Sbjct: 721 LRCSVPPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP 780
Query: 781 GSAEGTGQREEDSECLKEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840
SAE ++ +SE + +PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP
Sbjct: 781 DSAE--EKQLSESEYVGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 838
Query: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900
TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR
Sbjct: 839 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 898
Query: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950
QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 899 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 948
>gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo
sapiens]
Length = 950
Score = 1513 bits (3917), Expect = 0.0
Identities = 769/950 (80%), Positives = 829/950 (87%)
Query: 1 MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
ML S +G P + LLL LLILA W GSGQLHYSVPEEA+HGTFVGRIAQDLGLELAELV
Sbjct: 1 MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60
Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120
PRLF++ SK GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+
Sbjct: 61 PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120
Query: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180
V+V+DINDNPP+FP ++K + IAESRP ++RFPL+GASDADIG N+ LTYRL PN+YF L
Sbjct: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180
Query: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240
D S +Q+ L LVLRK LDREE E LLLTA+DGGKPELTGTVQLLIT+LD NDNAP
Sbjct: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240
Query: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300
F +++Y V + EN GTLVI NA+D D+G NGDI+YSF V P + F ++P +G
Sbjct: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300
Query: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360
I G +DFEE + ++I VEAVDKG P+AGHCTLLVEV+DVNDNAP++TI +LS+P++
Sbjct: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360
Query: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420
ED Q +IALISV D D+ +NGQVTC+LTPHVPFKLVSTYKNYYSLVLD ALDRESVSA
Sbjct: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420
Query: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480
YELVVTARDGGSPSLWATA VSV VADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA+
Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480
Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540
DADAQENALVSYSLVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD+
Sbjct: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540
Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600
GVPPLGSNVTLQVFVLDENDNAPALLTP G VSE++ RSVGAG VV KVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600
Query: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660
SGYNAWLSYELQ A IPFRVGLYTGEISTTR LDE DAP RLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660
Query: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
ATATVL+SLVESGQAP++SSRAS GA GPE LVDVNVYLIIAICAVSSLLVLTLLLYT
Sbjct: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720
Query: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL 780
LRCSA PTEG CAPGKPTLVCSSA GSWSYSQQRR RVCSGEG KTDLMAFSP L PC
Sbjct: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780
Query: 781 GSAEGTGQREEDSECLKEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840
GS E TG+ S+ +PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP
Sbjct: 781 GSTERTGEPSASSDSTGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840
Query: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900
TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR
Sbjct: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900
Query: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950
QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950
>gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens]
Length = 950
Score = 1512 bits (3914), Expect = 0.0
Identities = 771/950 (81%), Positives = 831/950 (87%)
Query: 1 MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
M+ S +GG R LLLWLL+LAAWE GSGQLHYS+PEEAKHGTFVGR+AQDLGLELAELV
Sbjct: 1 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60
Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120
PRLFRVASK H DLLEVNLQNGILFVNSRIDREELC SAECSIHLE+I DRPLQVFHVE
Sbjct: 61 PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120
Query: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180
VKV+DINDNPP+F ++ I I ESR +RFP++GA+DADIG N+ LTY L P+DYF+L
Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180
Query: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240
D + S E SL L LRK LDREE E LLLTA+DGGKPEL GTV+LLIT+LDVNDNAP
Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240
Query: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300
F Q+VY+V +LE NGTLV LNA+D D+G NG++V+SF + + F ++ ++G
Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300
Query: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360
EIR KLD+EE K YEI V+AVDKG+ PM+ HC +LV+VLDVNDNAPE+ +TSL LPIR
Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360
Query: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420
ED S +IALI+VSDRDSG+NGQVTC+L PHVPFKLVST+KNYYSLVLDSALDRES+S
Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420
Query: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480
YELVVTARDGGSPSLWATA VSV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA+
Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480
Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540
DADAQENALVSYSLVERRVGERALS+YVSVHAESGKVYALQPLDHEELELLQFQVSARD+
Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540
Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600
GVPPLGSNVTLQVFVLDENDNAPALL P G G VSEL+PR VGAGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD 600
Query: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660
SGYNAWLSYELQ AA GARIPFRVGLYTGEISTTR LDE D +RLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT 660
Query: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
ATATVL+SLVESGQAP+ASSRAS G GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
Query: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL 780
LRCS PPTEGA PGKPTLVCSSA GSWS SQQRR RVCS EGP KTDLMAFSP L P L
Sbjct: 721 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL 780
Query: 781 GSAEGTGQREEDSECLKEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840
++E Q E + + PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP
Sbjct: 781 NTSERNEQPEANLDLSGNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840
Query: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900
TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR
Sbjct: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900
Query: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950
QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950
>gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens]
Length = 936
Score = 1511 bits (3912), Expect = 0.0
Identities = 769/950 (80%), Positives = 830/950 (87%), Gaps = 14/950 (1%)
Query: 1 MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
M+ S +G R LLLWLL LA W+ GSGQLHYS+PEEAKHGTFVGRIAQDLGLELAELV
Sbjct: 1 MVYSRRGSLGSRLLLLWLL-LAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59
Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120
PRLFRVASK GDLLEVNLQNGILFVNSRIDREELC R AECSIHLEVIVDRPLQVFHVE
Sbjct: 60 PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119
Query: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180
V V+DINDNPP F ++R+ I ESR P++RFPL+GASD DIG N+ L YRL+PN+YF L
Sbjct: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179
Query: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240
D + + E+ + L LVLRK+LDREE QEH LL+ A+DGGKPELTGTVQLLI +LD NDNAP
Sbjct: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239
Query: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300
EF +S+Y V +LENA +GTLVIKLNA+D D+G N +IVY F V V F IN N G
Sbjct: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299
Query: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360
EI+ G+LD+E+ YEI+++A+DK P++GHC ++V++LDVNDN PE+ IT+L LP++
Sbjct: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359
Query: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420
ED S +IALISVSDRDSG+NGQVTC+L PHVPFKLVST+KNYYSLVLDSALDRESVS
Sbjct: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419
Query: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480
YELVVTARDGGSPSLWATASVSV VADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSA+
Sbjct: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479
Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540
DADAQENALVSYSLVERRVGER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARD+
Sbjct: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539
Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600
GVPPLGSNVTLQVFVLDENDNAPALL P G GG VSEL+PRSVGAGHVVAKVRAVD D
Sbjct: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599
Query: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660
SGYNAWLSYELQ A ARIPFRVGLYTGEISTTR LDE +AP HRLLVLVKDHGEP LT
Sbjct: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659
Query: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
ATATVL+SLVESGQAP+ASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719
Query: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL 780
LRCSA PTE C GKPTL+CSSA GSWSYSQQRR RVCSGE P KTDLMAFSPSLP
Sbjct: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLP--- 776
Query: 781 GSAEGTGQREEDSECLKEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840
G D+ PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP
Sbjct: 777 -----QGPTSTDN-----PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 826
Query: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900
TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR
Sbjct: 827 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 886
Query: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950
QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 887 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 936
>gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens]
Length = 937
Score = 1505 bits (3897), Expect = 0.0
Identities = 767/942 (81%), Positives = 822/942 (87%), Gaps = 13/942 (1%)
Query: 9 PRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68
P R LLL+++ILAAWE G GQLHYSVPEEAKHG FVGRIAQDLGLELAELVPRLFR
Sbjct: 9 PGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVC 68
Query: 69 KRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDIND 128
K GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIV+RPLQVFHV+V+V+DIND
Sbjct: 69 KFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDIND 128
Query: 129 NPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLEQ 188
NPP+FP +++ + IAESRP ++RFPL+GASDADIG N+ LTYRL PN+YF LD S +Q
Sbjct: 129 NPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQ 188
Query: 189 MSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVYK 248
+ L LVLRK LDREE E LLLTA+DGGKPELTGTVQLLIT+LD NDNAP F +++Y
Sbjct: 189 VKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYT 248
Query: 249 VTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGKL 308
V + EN GTLVI NA+D D+G NGDI+YSF V P + F ++P +G I G +
Sbjct: 249 VKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHM 308
Query: 309 DFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPSAI 368
DFEE + ++I VEAVDKG P+AGHCT+LVEV+DVNDNAP++T+TSLSLPI ED QP +
Sbjct: 309 DFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTV 368
Query: 369 IALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTAR 428
I LISV DRD G NGQVTC+LTP VPFKLVST+KNYYSLVLDSALDRESVSAYELVVTAR
Sbjct: 369 ITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTAR 428
Query: 429 DGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQENA 488
DGGSPSLWATASVSV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NA
Sbjct: 429 DGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNA 488
Query: 489 LVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLGSN 548
LVSYSLVE RVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD+GVPPLGSN
Sbjct: 489 LVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548
Query: 549 VTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWLS 608
VTLQVFVLDENDNAPALL P G GG V EL+PRSVGAGHVVAKVRAVDADSGYNAWLS
Sbjct: 549 VTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLS 608
Query: 609 YELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVLLS 668
YELQ A GA IPFRVGLYTGEISTTR LDE DAP HRLLVLVKDHGEP+LTATATVL+S
Sbjct: 609 YELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVS 668
Query: 669 LVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728
LVESGQAP+ASSRAS G GPE LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAP +
Sbjct: 669 LVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSS 728
Query: 729 EGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCLGSAEGTGQ 788
EGAC+ KPTLVCSSA GSWS+SQQRR RVCSGEGP KTDLMAFSPSLP S +
Sbjct: 729 EGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTD---- 784
Query: 789 REEDSECLKEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPE 848
PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPE
Sbjct: 785 ---------NPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPE 835
Query: 849 PEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQI 908
PEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQI
Sbjct: 836 PEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQI 895
Query: 909 DKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950
DKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 896 DKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 937
>gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo
sapiens]
Length = 941
Score = 1496 bits (3874), Expect = 0.0
Identities = 766/943 (81%), Positives = 822/943 (87%), Gaps = 9/943 (0%)
Query: 8 GPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67
GP ++LLL LL+LAAWE GSGQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFRVA
Sbjct: 8 GPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67
Query: 68 SKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDIN 127
SKRHGDLLEVNLQNGILFVNSRIDRE+LCGRSAECSIHLEVIVDRPLQVFHV+V+V+DIN
Sbjct: 68 SKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIN 127
Query: 128 DNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLE 187
DNPP+F E ++++ ++ES P ++ FPL+GASDADIGVNS LTY L N+ F L + +
Sbjct: 128 DNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKD 187
Query: 188 QMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVY 247
+ LVLRK LDRE+ + +LLL DGGKPELTG+VQ+ IT+LDVNDN P F + Y
Sbjct: 188 KSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSY 247
Query: 248 KVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGK 307
KV + EN N T VI+LNA+DPD+G NG+I Y + + + F+INP+ GEIR G+
Sbjct: 248 KVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGE 307
Query: 308 LDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPSA 367
LDFEE YEI V A+DKG MAGH +LVEVLDVNDN PEV +TSLSLP++ED Q
Sbjct: 308 LDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGT 367
Query: 368 IIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTA 427
+IALISVSDRDSG+NGQV C+LTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTA
Sbjct: 368 VIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTA 427
Query: 428 RDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQEN 487
RDGGSPSLWATA VSV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+N
Sbjct: 428 RDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKN 487
Query: 488 ALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLGS 547
ALVSYSLVERRVGE ALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD+GVPPLGS
Sbjct: 488 ALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS 547
Query: 548 NVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWL 607
NVTLQVFVLDENDNAPALL AGSAGG VSEL+PRSVGAGHVVAKVRAVDADSGYNAWL
Sbjct: 548 NVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWL 607
Query: 608 SYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVLL 667
SYELQ AAVGA IPF VGLYTGEISTTR LDE DAP HRLLVLVKDHGEPALT+TATVL+
Sbjct: 608 SYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLV 667
Query: 668 SLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPP 727
SLVE+GQAP+ SSRAS GAV PEAALVD+NVYLIIAICAVSSLLVLTLLLYTALRCSAPP
Sbjct: 668 SLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPP 727
Query: 728 TEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCLGSAEGTG 787
T CAPGKPTLVCSSA GSWSYSQQRR RVCS E P KTDLMAFSPSL
Sbjct: 728 TVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQL--------- 778
Query: 788 QREEDSECLKEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATP 847
RE+ EPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATP
Sbjct: 779 SREDCLNPPSEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATP 838
Query: 848 EPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQ 907
EPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQ
Sbjct: 839 EPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQ 898
Query: 908 IDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950
IDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 899 IDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 941
>gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo
sapiens]
Length = 948
Score = 1482 bits (3837), Expect = 0.0
Identities = 759/938 (80%), Positives = 818/938 (87%), Gaps = 3/938 (0%)
Query: 14 LLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGD 73
LLL LL+LAAWE GSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLFRVASKRHGD
Sbjct: 13 LLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASKRHGD 72
Query: 74 LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDINDNPPIF 133
LLEVNLQNGILFVNSRIDREELCGRS ECSIHLEVIVDRPLQVFHV+V+V+DINDNPP F
Sbjct: 73 LLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDNPPRF 132
Query: 134 PESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLEQMSSLS 193
+++++ I ESR ++RFPL+GASDAD+G N+ LTY+L PN+YF LD N ++
Sbjct: 133 SVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKDKFPV 192
Query: 194 LVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVYKVTVLE 253
LVLRK LDREE + LLLTA+DGGKPE TG+V LLI +LD NDNAP F + VY+V + E
Sbjct: 193 LVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEVKMYE 252
Query: 254 NAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGKLDFEEK 313
N N TLVI+LNA+D D+G N +++YSF V P + F IN GEI+ +DFE+
Sbjct: 253 NQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAIDFEDS 312
Query: 314 KLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPSAIIALIS 373
YEI V+ DKGN PM GHCT+LVE+LD NDN+PEV +TSLSLP++ED Q +IALIS
Sbjct: 313 NTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVIALIS 372
Query: 374 VSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433
VSD DSG+NGQVTC+LTPHVPFKLVSTYKNYYSLVLDSALDRE VSAYELVVTARDGGSP
Sbjct: 373 VSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARDGGSP 432
Query: 434 SLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQENALVSYS 493
LWATASVSV VADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQENALVSYS
Sbjct: 433 PLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS 492
Query: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLGSNVTLQV 553
LVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD GVPPLGSN+TLQV
Sbjct: 493 LVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNLTLQV 552
Query: 554 FVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWLSYELQL 613
FVLDENDNAPALL AGSAGG VSEL+ RSV AGHVVAKVRAVDADSGYNAWLSYELQ
Sbjct: 553 FVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSYELQS 612
Query: 614 AAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVLLSLVESG 673
AAVGARIPFRVGLYTGEISTTR LDE D+P RLLVLVKDHGEP+LTATATVL+SLVE
Sbjct: 613 AAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSLVEGS 672
Query: 674 QAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACA 733
QAP+ASSRAS G V PE ALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA PTEGAC
Sbjct: 673 QAPKASSRASVG-VAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPTEGACG 731
Query: 734 PGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPC-LGSAEGTGQREED 792
P KPTLVCSSA GSWSYSQQRR RVCSGEG K DLMAFSPSLPPC + +G Q
Sbjct: 732 PVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCPMVDVDGEDQ-SIG 790
Query: 793 SECLKEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAG 852
+ ++PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAG
Sbjct: 791 GDHSRKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAG 850
Query: 853 EVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSD 912
EVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSD
Sbjct: 851 EVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSD 910
Query: 913 FITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950
FITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 911 FITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 948
>gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo
sapiens]
Length = 824
Score = 1237 bits (3201), Expect = 0.0
Identities = 630/792 (79%), Positives = 692/792 (87%)
Query: 1 MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
ML SW+ P + LLL LL+LAA E GSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV
Sbjct: 1 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60
Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120
PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE
Sbjct: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120
Query: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180
V+V+DINDN P+FP + K + I+ESR P +RF L+GASDADIG NS LTY LD +YFTL
Sbjct: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180
Query: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240
D + + E++ SL LVL+K L+RE+ +H LL+TA DGGKPELTGT QL IT+LDVNDNAP
Sbjct: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240
Query: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300
F +++YKV +LENA NGTLV+ +NATD D+G N DI YSF + ++ F ++P NG
Sbjct: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300
Query: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360
+I KG +DFEE K YEI VEA DKGN PM+ HCT+L+E++D+NDN PE+ I SLSLP+
Sbjct: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360
Query: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420
ED+ S +IALISVSDRDSG NGQVTC+LTPHVPFKLVST+KNYYSLVLDS LDRESVSA
Sbjct: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420
Query: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480
YELVVTARDGGSPSLWATASVSV VADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSA+
Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480
Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540
DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD+
Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540
Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600
GVPPLGSNVTLQVFVLDENDNAPALL P G GG VSEL+PRSVGAGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600
Query: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660
SGYNAWLSYELQ GARIPFRVGLYTGEISTTR LDEVDAP HRLLVLVKDHGEP+LT
Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660
Query: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
ATATVL+SLVESGQAP+ASS+ASAGA GPEAALVDVNVYLI+AICAVSSLLVLTLLLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720
Query: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL 780
LRCSAPPTEG C PGKPTLVCSSA GSWSYSQQR+ RVCSGEG KTDLMAFSPSLPPC
Sbjct: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780
Query: 781 GSAEGTGQREED 792
S + +++ D
Sbjct: 781 ISRDREEKQDVD 792
>gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo
sapiens]
Length = 798
Score = 1229 bits (3180), Expect = 0.0
Identities = 628/774 (81%), Positives = 678/774 (87%)
Query: 4 SWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRL 63
SW G R+LLL LL+LAAWE G+GQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRL
Sbjct: 4 SWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRL 63
Query: 64 FRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKV 123
FRVASK G LLEVNLQNGILFVNSRIDREELC RSAECSIHLEVIVDRPLQVFHV+V+V
Sbjct: 64 FRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEV 123
Query: 124 RDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQ 183
RDINDNPP+FP ++K + IAESRP ++RFPL+GASDADIG N+ LTYRL PN+YF+L+
Sbjct: 124 RDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKP 183
Query: 184 NSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFY 243
E + L L+LRK+LDREE E L+LTA+DGGKPELTGTVQLLIT+LD NDNAP F
Sbjct: 184 PDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFD 243
Query: 244 QSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIR 303
+++YKV +LEN NGTLVIKLNA+D D+G NGDIVYSF + P V F I+P G+I
Sbjct: 244 RTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQII 303
Query: 304 TKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDT 363
KG +DFEE K YEI VE +DKG +P++GHC ++VEV D NDN P++ SLSLPIRED
Sbjct: 304 VKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDA 363
Query: 364 QPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYEL 423
+IALISVSD+D G NG VTC+LT HVPFKLVST+KNYYSLVLDSALDRESVSAYEL
Sbjct: 364 PLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYEL 423
Query: 424 VVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDAD 483
VVTARDGGSPSLWATASVSV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DAD
Sbjct: 424 VVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDAD 483
Query: 484 AQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVP 543
AQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARD+GVP
Sbjct: 484 AQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVP 543
Query: 544 PLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGY 603
PLGSNVTLQVFVLDENDNAPALL P AG GG VSEL+P SVG GHVVAKVRAVDADSGY
Sbjct: 544 PLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGY 603
Query: 604 NAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATA 663
NAWLSYELQ GARIPFRVGLYTGEISTTR LDE DAP HRLLVLVKDHGEPALTATA
Sbjct: 604 NAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATA 663
Query: 664 TVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRC 723
TVL+SLVESGQAP+ASSRA GAVGP+AALVDVNVYLIIAICAVSSLLVLTLLLYTALRC
Sbjct: 664 TVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRC 723
Query: 724 SAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLP 777
SA PTEGACAPGKPTLVCSSA GSWSYSQQRRPRVCSGEGP KTDLMAFSPSLP
Sbjct: 724 SALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLP 777
>gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo
sapiens]
Length = 814
Score = 1222 bits (3162), Expect = 0.0
Identities = 615/780 (78%), Positives = 681/780 (87%)
Query: 5 WQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLF 64
W+G +LLL LL+LAAW+ GSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLF
Sbjct: 5 WRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLF 64
Query: 65 RVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVR 124
RVASKRH DLLEV+LQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+V+V+
Sbjct: 65 RVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVK 124
Query: 125 DINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQN 184
D+NDNPP+F +++ ++ESR P++RFPL+GASDAD+G NS LTYRL +DYF LD +
Sbjct: 125 DVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNS 184
Query: 185 SLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQ 244
++ + LVLRK+LDRE+ H L LTA+DGGKPELTGTVQLL+T+LDVNDNAP F Q
Sbjct: 185 KNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQ 244
Query: 245 SVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRT 304
S Y+V + ENA NGT VIKLNA+DPD+G NG I YSF V V+ F+I+ N GEI
Sbjct: 245 SEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVI 304
Query: 305 KGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQ 364
+G LDFE++ LY+I ++A DKG+ PMAGHCT+LV +LD NDN PE+ +TSLSLP+RED Q
Sbjct: 305 RGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQ 364
Query: 365 PSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELV 424
+IALISV+D DSG+NGQVTC+L PHVPFKLVST+KNYYSLVLDSALDRE VSAYELV
Sbjct: 365 FGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELV 424
Query: 425 VTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADA 484
VTARDGGSPSLWATAS+SV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA+DADA
Sbjct: 425 VTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADA 484
Query: 485 QENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPP 544
QENALVSYSLVERRVGER+LSSY+SVH ESGKVYALQPLDHEELELLQFQVSARD+GVPP
Sbjct: 485 QENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPP 544
Query: 545 LGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYN 604
LGSNVTLQVFVLDENDNAPALL P G GG S+L+PRSVGAGHVVAKVRAVDADSGYN
Sbjct: 545 LGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYN 604
Query: 605 AWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATAT 664
AWLSYELQ AA RIPFRVGLYTGEISTTR LDE D+P HRLLVLVKDHGEPALTATAT
Sbjct: 605 AWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATAT 664
Query: 665 VLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCS 724
VL+SLVESGQAP+ASSR SAG +GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCS
Sbjct: 665 VLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCS 724
Query: 725 APPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCLGSAE 784
A PTEG C GKPTLVCSSA GSWSYSQQ+ RVCSGEGP KTDLMAFSP LPP LGS +
Sbjct: 725 ALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVD 784
>gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo
sapiens]
Length = 803
Score = 1216 bits (3145), Expect = 0.0
Identities = 617/788 (78%), Positives = 683/788 (86%), Gaps = 3/788 (0%)
Query: 14 LLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGD 73
LLL LL+LAAW+ GSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFR+ASK D
Sbjct: 14 LLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDRED 73
Query: 74 LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDINDNPPIF 133
LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+V+VRDINDNPP+F
Sbjct: 74 LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPLF 133
Query: 134 PESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLEQMSSLS 193
P ++R++I ESR P++ FPL+GASDAD+G NS LTY+L ++YF LD + + + +
Sbjct: 134 PVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIG 193
Query: 194 LVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVYKVTVLE 253
L+L+K+LDREE H+L LTA+DGGKPELTGTVQLL+T+LDVNDNAP F QS Y+V + E
Sbjct: 194 LLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFE 253
Query: 254 NAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGKLDFEEK 313
NA NGT VI+LNA+D D+G NG I YSF V V+ F+I+ N GEI +G LDFE++
Sbjct: 254 NADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQE 313
Query: 314 KLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPSAIIALIS 373
LY+I ++A DKG+ PMAGHCT+LV +LD NDN PE+ +TSLSLP+RED Q +IALIS
Sbjct: 314 NLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALIS 373
Query: 374 VSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433
V+D DSG+NGQV C+LTPHVPFKLVST+KNYYSLVLDSALDRESVSAYELVVTARDGGSP
Sbjct: 374 VNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433
Query: 434 SLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQENALVSYS 493
SLWATAS+SV VAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA+DADAQENALVSYS
Sbjct: 434 SLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYS 493
Query: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLGSNVTLQV 553
LVERRVGERALSSY+SVHAESGKVYALQPLDHEELELLQFQVSARD+GVPPLGSNVTLQV
Sbjct: 494 LVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQV 553
Query: 554 FVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWLSYELQL 613
FVLDENDNAPALL P G GG VSEL+PRS+GAG VVAKVRAVDADSGYNAWLSYELQ
Sbjct: 554 FVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSYELQP 613
Query: 614 AAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVLLSLVESG 673
A AR PFRVGLYTGEISTTR LDE D+P HRLLVLVKDHGEPALTATATVL+SLVESG
Sbjct: 614 PASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESG 673
Query: 674 QAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACA 733
QAP+ASSRAS GA GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGAC
Sbjct: 674 QAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACT 733
Query: 734 PGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPC---LGSAEGTGQRE 790
KPTLVCSSA GSWSYSQQRR RVCSGEGP K DLMAFSPSL PC +G AE E
Sbjct: 734 ADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAENQDLNE 793
Query: 791 EDSECLKE 798
+ + E
Sbjct: 794 DHDAKVSE 801
>gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo
sapiens]
Length = 810
Score = 1211 bits (3132), Expect = 0.0
Identities = 619/785 (78%), Positives = 687/785 (87%), Gaps = 5/785 (0%)
Query: 7 GGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRV 66
G PR L LWLL+L WE GSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV RLFRV
Sbjct: 10 GTPR---LQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRV 66
Query: 67 ASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDI 126
ASK HGDLLEVNLQNGILFVNSRIDREELCG+SAECSIHLEVIVDRPLQVFHV V+V+DI
Sbjct: 67 ASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDI 126
Query: 127 NDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSL 186
NDNPP+F +++++IAES+ ++RFPL+GASDADI N+ LTYRL N+YF+LD+ +
Sbjct: 127 NDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNG 186
Query: 187 EQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSV 246
+Q+ LSL+L+K+LDRE+ E +LLLTA+DGGKPELTGTV+LL+ +LDVNDN PEF +S
Sbjct: 187 KQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSE 246
Query: 247 YKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKG 306
YKV+++ENA TLV+KLNATD D+G NG++ YS + P + FT++ NNGE+R G
Sbjct: 247 YKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVNG 305
Query: 307 KLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPS 366
LD+EE K Y+I V+A DKG PMAGHCT+ VE+LD NDN+PEV +TSLSLP+RED QPS
Sbjct: 306 TLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPS 365
Query: 367 AIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVT 426
+IALISVSDRDSG NGQVTC+LTPHVPFKLVST+KNYYSLVLDSALDRE+V AYELVVT
Sbjct: 366 TVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVT 425
Query: 427 ARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQE 486
ARDGGSPSLWATA VSV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA+DADAQE
Sbjct: 426 ARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQE 485
Query: 487 NALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLG 546
NALVSYSLVERR+G+RALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD+GVPPL
Sbjct: 486 NALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLS 545
Query: 547 SNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAW 606
SNVTLQVFVLDENDNAPALL AGSAGG V++L+PRSVGAGHVVAKVRAVDADSGYNAW
Sbjct: 546 SNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNAW 605
Query: 607 LSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVL 666
LSYELQ AA G+RIPFRVGLYTGEISTTR LDE D+P HRLLVLVKDHGEPALTATATVL
Sbjct: 606 LSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVL 665
Query: 667 LSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAP 726
+SLVESGQAP+ASSR AGA PEAALVDVNVYLIIAIC VSSLLVLTLLLYTAL SA
Sbjct: 666 VSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSAT 725
Query: 727 PTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCLGSAEGT 786
PTEGACAPGKPTLVCS A GSWSYSQQRR RVCS EGP KTDLMAFSPSLP L E
Sbjct: 726 PTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNKEE-E 784
Query: 787 GQREE 791
G+R+E
Sbjct: 785 GERQE 789
>gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo
sapiens]
Length = 824
Score = 1207 bits (3122), Expect = 0.0
Identities = 625/784 (79%), Positives = 678/784 (86%)
Query: 1 MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
M SS + G LL LL+LAAWE GSGQL YSVPEEAKHGTFVGRIAQDLGLEL ELV
Sbjct: 1 MASSIRRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELV 60
Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120
PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIH+EVIVDRPLQVFHVE
Sbjct: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVE 120
Query: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180
V+V+DINDNPPIFP + K I ESR ++RFPL+GASDADIGVN+ L+Y+L +++F L
Sbjct: 121 VEVKDINDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFL 180
Query: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240
D Q + E SLSLVL K+LDREE E +LLL A+DGGKPELTGTVQ+LI +LDVNDN P
Sbjct: 181 DIQANDELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEP 240
Query: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300
F QSVYKV +LEN NGTLV+KLNA+D D+G N +IVYS V + FTI+P +G
Sbjct: 241 TFAQSVYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISG 300
Query: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360
EIRTKGKLD+EE K YEI V A DKG M+GHC + ++++D+NDN PEV+ITSLSLPI
Sbjct: 301 EIRTKGKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPIS 360
Query: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420
E+ +IALI+VSDRDSG+NG VTC+LTPHVPFKLVST+KNYYSLVLDSALDRESVSA
Sbjct: 361 ENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420
Query: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480
YELVVTARDGGSPSLWAT SVS+ VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA
Sbjct: 421 YELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480
Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540
DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARD+
Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 540
Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600
GVPPLGSNVTLQVFVLDENDNAPALL P AG+A G VSEL+P SVGAGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDAD 600
Query: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660
SGYNAWLSYELQL ARIPFRVGLYTGEISTTR LDE D+P HRLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALT 660
Query: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
ATATVL+SLVESGQAP+ASSRA GA G EA LVDVNVYLIIAICAVSSLLVLT+LLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTA 720
Query: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL 780
LRCS PPTEGA APGKPTLVCSSA GSWSYSQQRR RVCSGE P KTDLMAFSPSL
Sbjct: 721 LRCSVPPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP 780
Query: 781 GSAE 784
SAE
Sbjct: 781 DSAE 784
>gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo
sapiens]
Length = 816
Score = 1207 bits (3122), Expect = 0.0
Identities = 615/777 (79%), Positives = 675/777 (86%), Gaps = 1/777 (0%)
Query: 1 MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
M+ S +G R LLLWLL LA W+ GSGQLHYS+PEEAKHGTFVGRIAQDLGLELAELV
Sbjct: 1 MVYSRRGSLGSRLLLLWLL-LAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59
Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120
PRLFRVASK GDLLEVNLQNGILFVNSRIDREELC R AECSIHLEVIVDRPLQVFHVE
Sbjct: 60 PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119
Query: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180
V V+DINDNPP F ++R+ I ESR P++RFPL+GASD DIG N+ L YRL+PN+YF L
Sbjct: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179
Query: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240
D + + E+ + L LVLRK+LDREE QEH LL+ A+DGGKPELTGTVQLLI +LD NDNAP
Sbjct: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239
Query: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300
EF +S+Y V +LENA +GTLVIKLNA+D D+G N +IVY F V V F IN N G
Sbjct: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299
Query: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360
EI+ G+LD+E+ YEI+++A+DK P++GHC ++V++LDVNDN PE+ IT+L LP++
Sbjct: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359
Query: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420
ED S +IALISVSDRDSG+NGQVTC+L PHVPFKLVST+KNYYSLVLDSALDRESVS
Sbjct: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419
Query: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480
YELVVTARDGGSPSLWATASVSV VADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSA+
Sbjct: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479
Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540
DADAQENALVSYSLVERRVGER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARD+
Sbjct: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539
Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600
GVPPLGSNVTLQVFVLDENDNAPALL P G GG VSEL+PRSVGAGHVVAKVRAVD D
Sbjct: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599
Query: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660
SGYNAWLSYELQ A ARIPFRVGLYTGEISTTR LDE +AP HRLLVLVKDHGEP LT
Sbjct: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659
Query: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
ATATVL+SLVESGQAP+ASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719
Query: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLP 777
LRCSA PTE C GKPTL+CSSA GSWSYSQQRR RVCSGE P KTDLMAFSPSLP
Sbjct: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLP 776
>gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo
sapiens]
Length = 789
Score = 1201 bits (3107), Expect = 0.0
Identities = 615/781 (78%), Positives = 671/781 (85%)
Query: 9 PRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68
P R LLL+++ILAAWE G GQLHYSVPEEAKHG FVGRIAQDLGLELAELVPRLFR
Sbjct: 9 PGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVC 68
Query: 69 KRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDIND 128
K GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIV+RPLQVFHV+V+V+DIND
Sbjct: 69 KFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDIND 128
Query: 129 NPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLEQ 188
NPP+FP +++ + IAESRP ++RFPL+GASDADIG N+ LTYRL PN+YF LD S +Q
Sbjct: 129 NPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQ 188
Query: 189 MSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVYK 248
+ L LVLRK LDREE E LLLTA+DGGKPELTGTVQLLIT+LD NDNAP F +++Y
Sbjct: 189 VKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYT 248
Query: 249 VTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGKL 308
V + EN GTLVI NA+D D+G NGDI+YSF V P + F ++P +G I G +
Sbjct: 249 VKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHM 308
Query: 309 DFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPSAI 368
DFEE + ++I VEAVDKG P+AGHCT+LVEV+DVNDNAP++T+TSLSLPI ED QP +
Sbjct: 309 DFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTV 368
Query: 369 IALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTAR 428
I LISV DRD G NGQVTC+LTP VPFKLVST+KNYYSLVLDSALDRESVSAYELVVTAR
Sbjct: 369 ITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTAR 428
Query: 429 DGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQENA 488
DGGSPSLWATASVSV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NA
Sbjct: 429 DGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNA 488
Query: 489 LVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLGSN 548
LVSYSLVE RVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD+GVPPLGSN
Sbjct: 489 LVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548
Query: 549 VTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWLS 608
VTLQVFVLDENDNAPALL P G GG V EL+PRSVGAGHVVAKVRAVDADSGYNAWLS
Sbjct: 549 VTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLS 608
Query: 609 YELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVLLS 668
YELQ A GA IPFRVGLYTGEISTTR LDE DAP HRLLVLVKDHGEP+LTATATVL+S
Sbjct: 609 YELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVS 668
Query: 669 LVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728
LVESGQAP+ASSRAS G GPE LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAP +
Sbjct: 669 LVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSS 728
Query: 729 EGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCLGSAEGTGQ 788
EGAC+ KPTLVCSSA GSWS+SQQRR RVCSGEGP KTDLMAFSPSLP S +
Sbjct: 729 EGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTDNVSH 788
Query: 789 R 789
+
Sbjct: 789 K 789
>gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens]
Length = 842
Score = 1200 bits (3104), Expect = 0.0
Identities = 617/794 (77%), Positives = 676/794 (85%)
Query: 1 MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
ML S +G P + LLL LLILA W GSGQLHYSVPEEA+HGTFVGRIAQDLGLELAELV
Sbjct: 1 MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60
Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120
PRLF++ SK GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+
Sbjct: 61 PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120
Query: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180
V+V+DINDNPP+FP ++K + IAESRP ++RFPL+GASDADIG N+ LTYRL PN+YF L
Sbjct: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180
Query: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240
D S +Q+ L LVLRK LDREE E LLLTA+DGGKPELTGTVQLLIT+LD NDNAP
Sbjct: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240
Query: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300
F +++Y V + EN GTLVI NA+D D+G NGDI+YSF V P + F ++P +G
Sbjct: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300
Query: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360
I G +DFEE + ++I VEAVDKG P+AGHCTLLVEV+DVNDNAP++TI +LS+P++
Sbjct: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360
Query: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420
ED Q +IALISV D D+ +NGQVTC+LTPHVPFKLVSTYKNYYSLVLD ALDRESVSA
Sbjct: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420
Query: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480
YELVVTARDGGSPSLWATA VSV VADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA+
Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480
Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540
DADAQENALVSYSLVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD+
Sbjct: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540
Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600
GVPPLGSNVTLQVFVLDENDNAPALLTP G VSE++ RSVGAG VV KVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600
Query: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660
SGYNAWLSYELQ A IPFRVGLYTGEISTTR LDE DAP RLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660
Query: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
ATATVL+SLVESGQAP++SSRAS GA GPE LVDVNVYLIIAICAVSSLLVLTLLLYT
Sbjct: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720
Query: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL 780
LRCSA PTEG CAPGKPTLVCSSA GSWSYSQQRR RVCSGEG KTDLMAFSP L PC
Sbjct: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780
Query: 781 GSAEGTGQREEDSE 794
GS E TG+ S+
Sbjct: 781 GSTERTGEPSASSD 794
>gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 807
Score = 1199 bits (3103), Expect = 0.0
Identities = 619/790 (78%), Positives = 677/790 (85%)
Query: 1 MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
M+ S +GG R LLLWLL+LAAWE GSGQLHYS+PEEAKHGTFVGR+AQDLGLELAELV
Sbjct: 1 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60
Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120
PRLFRVASK H DLLEVNLQNGILFVNSRIDREELC SAECSIHLE+I DRPLQVFHVE
Sbjct: 61 PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120
Query: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180
VKV+DINDNPP+F ++ I I ESR +RFP++GA+DADIG N+ LTY L P+DYF+L
Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180
Query: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240
D + S E SL L LRK LDREE E LLLTA+DGGKPEL GTV+LLIT+LDVNDNAP
Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240
Query: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300
F Q+VY+V +LE NGTLV LNA+D D+G NG++V+SF + + F ++ ++G
Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300
Query: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360
EIR KLD+EE K YEI V+AVDKG+ PM+ HC +LV+VLDVNDNAPE+ +TSL LPIR
Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360
Query: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420
ED S +IALI+VSDRDSG+NGQVTC+L PHVPFKLVST+KNYYSLVLDSALDRES+S
Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420
Query: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480
YELVVTARDGGSPSLWATA VSV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA+
Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480
Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540
DADAQENALVSYSLVERRVGERALS+YVSVHAESGKVYALQPLDHEELELLQFQVSARD+
Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540
Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600
GVPPLGSNVTLQVFVLDENDNAPALL P G G VSEL+PR VGAGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD 600
Query: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660
SGYNAWLSYELQ AA GARIPFRVGLYTGEISTTR LDE D +RLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT 660
Query: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
ATATVL+SLVESGQAP+ASSRAS G GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
Query: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL 780
LRCS PPTEGA PGKPTLVCSSA GSWS SQQRR RVCS EGP KTDLMAFSP L P L
Sbjct: 721 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL 780
Query: 781 GSAEGTGQRE 790
++E Q E
Sbjct: 781 NTSERNEQPE 790
>gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo
sapiens]
Length = 792
Score = 1189 bits (3076), Expect = 0.0
Identities = 611/769 (79%), Positives = 666/769 (86%)
Query: 8 GPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67
GP ++LLL LL+LAAWE GSGQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFRVA
Sbjct: 8 GPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67
Query: 68 SKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDIN 127
SKRHGDLLEVNLQNGILFVNSRIDRE+LCGRSAECSIHLEVIVDRPLQVFHV+V+V+DIN
Sbjct: 68 SKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIN 127
Query: 128 DNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLE 187
DNPP+F E ++++ ++ES P ++ FPL+GASDADIGVNS LTY L N+ F L + +
Sbjct: 128 DNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKD 187
Query: 188 QMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVY 247
+ LVLRK LDRE+ + +LLL DGGKPELTG+VQ+ IT+LDVNDN P F + Y
Sbjct: 188 KSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSY 247
Query: 248 KVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGK 307
KV + EN N T VI+LNA+DPD+G NG+I Y + + + F+INP+ GEIR G+
Sbjct: 248 KVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGE 307
Query: 308 LDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPSA 367
LDFEE YEI V A+DKG MAGH +LVEVLDVNDN PEV +TSLSLP++ED Q
Sbjct: 308 LDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGT 367
Query: 368 IIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTA 427
+IALISVSDRDSG+NGQV C+LTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTA
Sbjct: 368 VIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTA 427
Query: 428 RDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQEN 487
RDGGSPSLWATA VSV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+N
Sbjct: 428 RDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKN 487
Query: 488 ALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLGS 547
ALVSYSLVERRVGE ALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD+GVPPLGS
Sbjct: 488 ALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS 547
Query: 548 NVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWL 607
NVTLQVFVLDENDNAPALL AGSAGG VSEL+PRSVGAGHVVAKVRAVDADSGYNAWL
Sbjct: 548 NVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWL 607
Query: 608 SYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVLL 667
SYELQ AAVGA IPF VGLYTGEISTTR LDE DAP HRLLVLVKDHGEPALT+TATVL+
Sbjct: 608 SYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLV 667
Query: 668 SLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPP 727
SLVE+GQAP+ SSRAS GAV PEAALVD+NVYLIIAICAVSSLLVLTLLLYTALRCSAPP
Sbjct: 668 SLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPP 727
Query: 728 TEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSL 776
T CAPGKPTLVCSSA GSWSYSQQRR RVCS E P KTDLMAFSPSL
Sbjct: 728 TVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776
>gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo
sapiens]
Length = 844
Score = 1175 bits (3039), Expect = 0.0
Identities = 605/766 (78%), Positives = 659/766 (86%), Gaps = 1/766 (0%)
Query: 14 LLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGD 73
LLL LL+LAAWE GSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLFRVASKRHGD
Sbjct: 13 LLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASKRHGD 72
Query: 74 LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDINDNPPIF 133
LLEVNLQNGILFVNSRIDREELCGRS ECSIHLEVIVDRPLQVFHV+V+V+DINDNPP F
Sbjct: 73 LLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDNPPRF 132
Query: 134 PESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLEQMSSLS 193
+++++ I ESR ++RFPL+GASDAD+G N+ LTY+L PN+YF LD N ++
Sbjct: 133 SVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKDKFPV 192
Query: 194 LVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVYKVTVLE 253
LVLRK LDREE + LLLTA+DGGKPE TG+V LLI +LD NDNAP F + VY+V + E
Sbjct: 193 LVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEVKMYE 252
Query: 254 NAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGKLDFEEK 313
N N TLVI+LNA+D D+G N +++YSF V P + F IN GEI+ +DFE+
Sbjct: 253 NQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAIDFEDS 312
Query: 314 KLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPSAIIALIS 373
YEI V+ DKGN PM GHCT+LVE+LD NDN+PEV +TSLSLP++ED Q +IALIS
Sbjct: 313 NTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVIALIS 372
Query: 374 VSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433
VSD DSG+NGQVTC+LTPHVPFKLVSTYKNYYSLVLDSALDRE VSAYELVVTARDGGSP
Sbjct: 373 VSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARDGGSP 432
Query: 434 SLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQENALVSYS 493
LWATASVSV VADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQENALVSYS
Sbjct: 433 PLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS 492
Query: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLGSNVTLQV 553
LVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD GVPPLGSN+TLQV
Sbjct: 493 LVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNLTLQV 552
Query: 554 FVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWLSYELQL 613
FVLDENDNAPALL AGSAGG VSEL+ RSV AGHVVAKVRAVDADSGYNAWLSYELQ
Sbjct: 553 FVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSYELQS 612
Query: 614 AAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVLLSLVESG 673
AAVGARIPFRVGLYTGEISTTR LDE D+P RLLVLVKDHGEP+LTATATVL+SLVE
Sbjct: 613 AAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSLVEGS 672
Query: 674 QAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACA 733
QAP+ASSRAS G V PE ALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA PTEGAC
Sbjct: 673 QAPKASSRASVG-VAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPTEGACG 731
Query: 734 PGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPC 779
P KPTLVCSSA GSWSYSQQRR RVCSGEG K DLMAFSPSLPPC
Sbjct: 732 PVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPC 777
>gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo
sapiens]
Length = 686
Score = 798 bits (2060), Expect = 0.0
Identities = 398/521 (76%), Positives = 455/521 (87%)
Query: 14 LLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGD 73
LLL LL+LAAW+ GSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFR+ASK D
Sbjct: 14 LLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDRED 73
Query: 74 LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDINDNPPIF 133
LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+V+VRDINDNPP+F
Sbjct: 74 LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPLF 133
Query: 134 PESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLEQMSSLS 193
P ++R++I ESR P++ FPL+GASDAD+G NS LTY+L ++YF LD + + + +
Sbjct: 134 PVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIG 193
Query: 194 LVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVYKVTVLE 253
L+L+K+LDREE H+L LTA+DGGKPELTGTVQLL+T+LDVNDNAP F QS Y+V + E
Sbjct: 194 LLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFE 253
Query: 254 NAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGKLDFEEK 313
NA NGT VI+LNA+D D+G NG I YSF V V+ F+I+ N GEI +G LDFE++
Sbjct: 254 NADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQE 313
Query: 314 KLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPSAIIALIS 373
LY+I ++A DKG+ PMAGHCT+LV +LD NDN PE+ +TSLSLP+RED Q +IALIS
Sbjct: 314 NLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALIS 373
Query: 374 VSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433
V+D DSG+NGQV C+LTPHVPFKLVST+KNYYSLVLDSALDRESVSAYELVVTARDGGSP
Sbjct: 374 VNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433
Query: 434 SLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQENALVSYS 493
SLWATAS+SV VAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA+DADAQENALVSYS
Sbjct: 434 SLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYS 493
Query: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQ 534
LVERRVGERALSSY+SVHAESGKVYALQPLDHEELELLQFQ
Sbjct: 494 LVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQ 534
Score = 320 bits (820), Expect = 4e-87
Identities = 155/161 (96%), Positives = 158/161 (98%), Gaps = 1/161 (0%)
Query: 791 EDSECLK-EPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 849
E+ E L+ +PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP
Sbjct: 526 EELELLQFQPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 585
Query: 850 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 909
EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID
Sbjct: 586 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 645
Query: 910 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950
KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 646 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 686
Score = 153 bits (386), Expect = 8e-37
Identities = 108/341 (31%), Positives = 161/341 (47%), Gaps = 21/341 (6%)
Query: 338 VEVLDVNDNAPEVTITSLSLPIREDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPF-- 395
VEV D+NDN P + + I E P ++ L SD D GSN +T L+ F
Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180
Query: 396 --KLVSTYKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWATASVSVGVADVNDNAP 453
K+ S L+L +LDRE A+ L +TA DGG P L T + V V DVNDNAP
Sbjct: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240
Query: 454 AFAQPEYTVFVKENNPPGCHIFTVSAQDADAQENALVSYSLVERRVGERALSSYVSVHAE 513
F Q EY V + EN G + ++A D D N +SYS + + + S+
Sbjct: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSF--NSLVAAMVIDHFSIDRN 298
Query: 514 SGKVYALQPLDHEELELLQFQVSARDSGVPPLGSNVTLQVFVLDENDNAPALLTPGAGSA 573
+G++ LD E+ L + + A D G PP+ + T+ V +LD+NDN P + A
Sbjct: 299 TGEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEI-------A 351
Query: 574 GGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWLSYELQLAAVGARIPFR-VGLYTGEIS 632
++S + G V+A + D DSG N ++ L +PF+ V + S
Sbjct: 352 LTSLSLPVREDAQFGTVIALISVNDLDSGANGQVNCSLT-----PHVPFKLVSTFKNYYS 406
Query: 633 TT--RPLDEVDAPHHRLLVLVKDHGEPALTATATVLLSLVE 671
LD + L+V +D G P+L ATA++ + + +
Sbjct: 407 LVLDSALDRESVSAYELVVTARDGGSPSLWATASLSVEVAD 447
Score = 150 bits (380), Expect = 4e-36
Identities = 117/416 (28%), Positives = 190/416 (45%), Gaps = 19/416 (4%)
Query: 230 ITILDVNDNAPEFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAV 289
+ + D+NDN P F +V + E+ ++ A+D D G+N + Y + +
Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180
Query: 290 VYAFTINPNNG-EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAP 348
+ N + K LD EE + + + A D G + G LLV VLDVNDNAP
Sbjct: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240
Query: 349 EVTITSLSLPIREDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTY---KNYY 405
+ + I E+ + ++ SDRD G+NG ++ + V ++ + +N
Sbjct: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300
Query: 406 SLVLDSALDRESVSAYELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVK 465
+V+ LD E + Y++++ A D G P + +V V + D NDN P A ++ V+
Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360
Query: 466 ENNPPGCHIFTVSAQDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDH 525
E+ G I +S D D+ N V+ SL V + +S++ + ++ + LD
Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPH-VPFKLVSTFKNYYS----LVLDSALDR 415
Query: 526 EELELLQFQVSARDSGVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSV 585
E + + V+ARD G P L + +L V V D NDNAPA P + + +
Sbjct: 416 ESVSAYELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQP-------EYTVFVKENN 468
Query: 586 GAGHVVAKVRAVDADSGYNAWLSYELQLAAVGARI---PFRVGLYTGEISTTRPLD 638
G + V A DAD+ NA +SY L VG R V +G++ +PLD
Sbjct: 469 PPGCHIFTVSARDADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLD 524
>gi|14165402 protocadherin alpha 1 isoform 3 precursor [Homo
sapiens]
Length = 686
Score = 792 bits (2045), Expect = 0.0
Identities = 404/534 (75%), Positives = 455/534 (85%)
Query: 1 MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
M+ S +GG R LLLWLL+LAAWE GSGQLHYS+PEEAKHGTFVGR+AQDLGLELAELV
Sbjct: 1 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60
Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120
PRLFRVASK H DLLEVNLQNGILFVNSRIDREELC SAECSIHLE+I DRPLQVFHVE
Sbjct: 61 PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120
Query: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180
VKV+DINDNPP+F ++ I I ESR +RFP++GA+DADIG N+ LTY L P+DYF+L
Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180
Query: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240
D + S E SL L LRK LDREE E LLLTA+DGGKPEL GTV+LLIT+LDVNDNAP
Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240
Query: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300
F Q+VY+V +LE NGTLV LNA+D D+G NG++V+SF + + F ++ ++G
Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300
Query: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360
EIR KLD+EE K YEI V+AVDKG+ PM+ HC +LV+VLDVNDNAPE+ +TSL LPIR
Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360
Query: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420
ED S +IALI+VSDRDSG+NGQVTC+L PHVPFKLVST+KNYYSLVLDSALDRES+S
Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420
Query: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480
YELVVTARDGGSPSLWATA VSV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA+
Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480
Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQ 534
DADAQENALVSYSLVERRVGERALS+YVSVHAESGKVYALQPLDHEELELLQFQ
Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQ 534
Score = 320 bits (820), Expect = 4e-87
Identities = 155/161 (96%), Positives = 158/161 (98%), Gaps = 1/161 (0%)
Query: 791 EDSECLK-EPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 849
E+ E L+ +PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP
Sbjct: 526 EELELLQFQPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 585
Query: 850 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 909
EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID
Sbjct: 586 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 645
Query: 910 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950
KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 646 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 686
Score = 139 bits (349), Expect = 2e-32
Identities = 111/344 (32%), Positives = 160/344 (46%), Gaps = 27/344 (7%)
Query: 338 VEVLDVNDNAPEVTITSLSLPIREDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKL 397
V+V D+NDN P + I E ++ + +D D G+N +T TL+P F L
Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180
Query: 398 VSTYKNYYS----LVLDSALDRESVSAYELVVTARDGGSPSLWATASVSVGVADVNDNAP 453
+ S L L LDRE L++TA DGG P L T + + V DVNDNAP
Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240
Query: 454 AFAQPEYTVFVKENNPPGCHIFTVSAQDADAQENALVSYSL---VERRVGERALSSYVSV 510
F Q Y V + E G + T++A DAD N V +S + R + E+ V
Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEK-----FKV 295
Query: 511 HAESGKVYALQPLDHEELELLQFQVSARDSGVPPLGSNVTLQVFVLDENDNAPALLTPGA 570
+ SG++ + LD+EE + + QV A D G PP+ ++ + V VLD NDNAP L
Sbjct: 296 DSSSGEIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPEL---AV 352
Query: 571 GSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWLSYELQLAAVGARIPFR-VGLYTG 629
S + E P S V+A + D DSG N ++ L +PF+ V +
Sbjct: 353 TSLYLPIREDAPLST----VIALITVSDRDSGANGQVTCSLM-----PHVPFKLVSTFKN 403
Query: 630 EISTT--RPLDEVDAPHHRLLVLVKDHGEPALTATATVLLSLVE 671
S LD + L+V +D G P+L ATA V + + +
Sbjct: 404 YYSLVLDSALDRESLSVYELVVTARDGGSPSLWATARVSVEVAD 447
Score = 138 bits (348), Expect = 2e-32
Identities = 118/420 (28%), Positives = 187/420 (44%), Gaps = 27/420 (6%)
Query: 230 ITILDVNDNAPEFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAV 289
+ + D+NDN P F + + E+ + A D D G N + Y+ P+
Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLS----PSD 176
Query: 290 VYAFTINPNNGEIRT-----KGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVN 344
++ + ++ ++ + LD EE + + A D G + G LL+ VLDVN
Sbjct: 177 YFSLDVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVN 236
Query: 345 DNAPEVTITSLSLPIREDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNY 404
DNAP + + E T ++ ++ SD D G NG+V + + + +K
Sbjct: 237 DNAPLFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVD 296
Query: 405 YS---LVLDSALDRESVSAYELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYT 461
S + L LD E +YE+ V A D GSP + V V V DVNDNAP A
Sbjct: 297 SSSGEIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLY 356
Query: 462 VFVKENNPPGCHIFTVSAQDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQ 521
+ ++E+ P I ++ D D+ N V+ SL+ V + +S++ + ++ +
Sbjct: 357 LPIREDAPLSTVIALITVSDRDSGANGQVTCSLMPH-VPFKLVSTFKNYYS----LVLDS 411
Query: 522 PLDHEELELLQFQVSARDSGVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELM 581
LD E L + + V+ARD G P L + + V V D NDNAPA P + +
Sbjct: 412 ALDRESLSVYELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQP-------EYTVFV 464
Query: 582 PRSVGAGHVVAKVRAVDADSGYNAWLSYELQLAAVGARI---PFRVGLYTGEISTTRPLD 638
+ G + V A DAD+ NA +SY L VG R V +G++ +PLD
Sbjct: 465 KENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLD 524
>gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo
sapiens]
Length = 685
Score = 771 bits (1992), Expect = 0.0
Identities = 392/521 (75%), Positives = 440/521 (84%)
Query: 14 LLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGD 73
LLL LL+LAAWE GSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLFRVASKRHGD
Sbjct: 13 LLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASKRHGD 72
Query: 74 LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDINDNPPIF 133
LLEVNLQNGILFVNSRIDREELCGRS ECSIHLEVIVDRPLQVFHV+V+V+DINDNPP F
Sbjct: 73 LLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDNPPRF 132
Query: 134 PESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLEQMSSLS 193
+++++ I ESR ++RFPL+GASDAD+G N+ LTY+L PN+YF LD N ++
Sbjct: 133 SVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKDKFPV 192
Query: 194 LVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVYKVTVLE 253
LVLRK LDREE + LLLTA+DGGKPE TG+V LLI +LD NDNAP F + VY+V + E
Sbjct: 193 LVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEVKMYE 252
Query: 254 NAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGKLDFEEK 313
N N TLVI+LNA+D D+G N +++YSF V P + F IN GEI+ +DFE+
Sbjct: 253 NQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAIDFEDS 312
Query: 314 KLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPSAIIALIS 373
YEI V+ DKGN PM GHCT+LVE+LD NDN+PEV +TSLSLP++ED Q +IALIS
Sbjct: 313 NTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVIALIS 372
Query: 374 VSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433
VSD DSG+NGQVTC+LTPHVPFKLVSTYKNYYSLVLDSALDRE VSAYELVVTARDGGSP
Sbjct: 373 VSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARDGGSP 432
Query: 434 SLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQENALVSYS 493
LWATASVSV VADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQENALVSYS
Sbjct: 433 PLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS 492
Query: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQ 534
LVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQ
Sbjct: 493 LVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQ 533
Score = 320 bits (820), Expect = 4e-87
Identities = 155/161 (96%), Positives = 158/161 (98%), Gaps = 1/161 (0%)
Query: 791 EDSECLK-EPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 849
E+ E L+ +PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP
Sbjct: 525 EELELLQFQPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 584
Query: 850 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 909
EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID
Sbjct: 585 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 644
Query: 910 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950
KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 645 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 685
Score = 135 bits (341), Expect = 1e-31
Identities = 102/341 (29%), Positives = 156/341 (45%), Gaps = 21/341 (6%)
Query: 338 VEVLDVNDNAPEVTITSLSLPIREDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKL 397
VEV D+NDN P ++T L I E + L SD D G N +T L+P+ F L
Sbjct: 120 VEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVL 179
Query: 398 VSTYKN----YYSLVLDSALDRESVSAYELVVTARDGGSPSLWATASVSVGVADVNDNAP 453
K + LVL LDRE +L++TA DGG P + S+ + V D NDNAP
Sbjct: 180 DIINKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAP 239
Query: 454 AFAQPEYTVFVKENNPPGCHIFTVSAQDADAQENALVSYSLVERRVGERALSSYVSVHAE 513
F +P Y V + EN + ++A D+D N + YS + + ++
Sbjct: 240 IFDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSS--LVPPTIRRKFWINER 297
Query: 514 SGKVYALQPLDHEELELLQFQVSARDSGVPPLGSNVTLQVFVLDENDNAPALLTPGAGSA 573
+G++ +D E+ + V D G PP+ + T+ V +LDENDN+P ++
Sbjct: 298 TGEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVT----- 352
Query: 574 GGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWLSYELQLAAVGARIPFR-VGLYTGEIS 632
++S + G V+A + D DSG N ++ L +PF+ V Y S
Sbjct: 353 --SLSLPVKEDAQVGTVIALISVSDHDSGANGQVTCSLT-----PHVPFKLVSTYKNYYS 405
Query: 633 TT--RPLDEVDAPHHRLLVLVKDHGEPALTATATVLLSLVE 671
LD + L+V +D G P L ATA+V + + +
Sbjct: 406 LVLDSALDRERVSAYELVVTARDGGSPPLWATASVSVEVAD 446
Score = 130 bits (327), Expect = 6e-30
Identities = 111/416 (26%), Positives = 190/416 (45%), Gaps = 19/416 (4%)
Query: 230 ITILDVNDNAPEFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAV 289
+ + D+NDN P F + K+++ E+ + A+D D G N + Y + +
Sbjct: 120 VEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVL 179
Query: 290 VYAFTINPNNGEIRTKGKL-DFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAP 348
+ + + KL D EE ++ + A D G G +LL+ VLD NDNAP
Sbjct: 180 DIINKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAP 239
Query: 349 EVTITSLSLPIREDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTY---KNYY 405
+ + E+ ++ ++ SD D G N ++ + + VP + + +
Sbjct: 240 IFDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTG 299
Query: 406 SLVLDSALDRESVSAYELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVK 465
+ ++ A+D E + YE+ V D G+P + +V V + D NDN+P ++ VK
Sbjct: 300 EIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVK 359
Query: 466 ENNPPGCHIFTVSAQDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDH 525
E+ G I +S D D+ N V+ SL V + +S+Y + ++ + LD
Sbjct: 360 EDAQVGTVIALISVSDHDSGANGQVTCSLTPH-VPFKLVSTYKNYYS----LVLDSALDR 414
Query: 526 EELELLQFQVSARDSGVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSV 585
E + + V+ARD G PPL + ++ V V D NDNAPA A + + +
Sbjct: 415 ERVSAYELVVTARDGGSPPLWATASVSVEVADVNDNAPAF-------AQSEYTVFVKENN 467
Query: 586 GAGHVVAKVRAVDADSGYNAWLSYELQLAAVGAR-IPFRVGLY--TGEISTTRPLD 638
G + V A DAD+ NA +SY L +G R + V ++ +G++ +PLD
Sbjct: 468 PPGCHIFTVSAWDADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLD 523
Score = 85.1 bits (209), Expect = 3e-16
Identities = 81/272 (29%), Positives = 119/272 (43%), Gaps = 19/272 (6%)
Query: 441 VSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQENALVSYSLVERRVG 500
V V V D+NDN P F+ E + + E+ A DAD ENAL++Y L
Sbjct: 118 VDVEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYF 177
Query: 501 ERALSSYVSVHAESGKVYALQPL-DHEELELLQFQVSARDSGVPPLGSNVTLQVFVLDEN 559
L + V L+ L D EE L+ ++A D G P +V+L + VLD N
Sbjct: 178 --VLDIINKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDAN 235
Query: 560 DNAPALLTPGAGSAGGTVSEL-MPRSVGAGHVVAKVRAVDADSGYNAWLSYELQ-LAAVG 617
DNAP P V E+ M + +V ++ A D+D G N + Y L
Sbjct: 236 DNAPIFDRP--------VYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPT 287
Query: 618 ARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVLLSLV-ESGQAP 676
R F + TGEI +D D+ + + V V D G P + TVL+ L+ E+ +P
Sbjct: 288 IRRKFWINERTGEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSP 347
Query: 677 QASSRASAGAVGPEAALVDVNVYLIIAICAVS 708
+ + + V D V +IA+ +VS
Sbjct: 348 EVIVTSLSLPVKE-----DAQVGTVIALISVS 374
>gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 625 bits (1613), Expect = e-179
Identities = 375/939 (39%), Positives = 538/939 (57%), Gaps = 44/939 (4%)
Query: 14 LLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGD 73
+LL +L+ WETG Q+ YSVPEE + G+ VG I++DLGLE EL R R+ +
Sbjct: 14 VLLGILLGTLWETGCTQIRYSVPEELEKGSRVGDISRDLGLEPRELAERGVRIIPRGRTQ 73
Query: 74 LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDINDNPPIF 133
L +N ++G L RIDREELC + +C ++L+++++ ++++ VEV+VRDINDN P F
Sbjct: 74 LFALNPRSGSLVTAGRIDREELCMGAIKCQLNLDILMEDKVKIYGVEVEVRDINDNAPYF 133
Query: 134 PESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLEQMSSLS 193
ES+ I I+E+ E RFPL A D DIG NS +Y L PN +F+L QN +
Sbjct: 134 RESELEIKISENAATEMRFPLPHAWDPDIGKNSLQSYELSPNTHFSLIVQNGADGSKYPE 193
Query: 194 LVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVYKVTVLE 253
LVL++ LDREE H L+LTASDGG P TGT ++ + +LD NDNAP F Q Y+ +V E
Sbjct: 194 LVLKRALDREEKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDNAPAFAQPEYRASVPE 253
Query: 254 NAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGKLDFEEK 313
N GT ++ +NATDPD+G N ++ YSFR V F ++ N+G I T G+LD EE
Sbjct: 254 NLALGTQLLVVNATDPDEGVNAEVRYSFRY-VDDKAAQVFKLDCNSGTISTIGELDHEES 312
Query: 314 KLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPSAIIALIS 373
Y++ V+A+D N + +L+ VLDVNDNAPEV +TSL+ + E++ +IAL++
Sbjct: 313 GFYQMEVQAMD--NAGYSARAKVLITVLDVNDNAPEVVLTSLASSVPENSPRGTLIALLN 370
Query: 374 VSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433
V+D+DS NGQV C + ++PFKL +Y NYYSLV D LDRE V +Y + VTA D G+P
Sbjct: 371 VNDQDSEENGQVICFIQGNLPFKLEKSYGNYYSLVTDIVLDREQVPSYNITVTATDRGTP 430
Query: 434 SLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQENALVSYS 493
L +S+ VAD NDN P F Q Y+ ++ ENNP G + +V+A D D +ENA ++YS
Sbjct: 431 PLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLVSVTAHDPDCEENAQITYS 490
Query: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLGSNVTLQV 553
L E + +LSSYVS+++++G +YAL D+E+ LQ +V ARD+G PPL SNV+L +
Sbjct: 491 LAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVKVMARDNGHPPLSSNVSLSL 550
Query: 554 FVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWLSYELQL 613
FVLD+NDNAP +L P + G T EL PRS G++V KV AVD DSG NAWLSY L
Sbjct: 551 FVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLK 610
Query: 614 AAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVLLSLVESG 673
A+ F VGL+TGE+ T R L + DA L+V V+DHG+P L+AT T+ +++ +S
Sbjct: 611 ASEPGL--FSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADS- 667
Query: 674 QAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALR------CSAPP 727
PQ + + + D+ +YL++A+ AVS + + ++L ALR
Sbjct: 668 -IPQVLADLGSLESPANSETSDLTLYLVVAVAAVSCVFLAFVILLLALRLRRWHKSRLLQ 726
Query: 728 TEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCLGSAEGTG 787
G G P G ++ Q V K+ L+ P+ L S E
Sbjct: 727 ASGGGLTGAPASHFVGVDGVQAFLQTYSHEVSLTTDSRKSHLIFPQPNYADMLVSQESFE 786
Query: 788 QRE-----------EDSECLKEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPD 836
+ E +DS L E PN DWR+S + R G S + ++ G P+
Sbjct: 787 KSEPLLLSGDSVFSKDSHGLIEQAPPNTDWRFSQAQRPGTSGSQNGDDTGT------WPN 840
Query: 837 QQWPT-------VSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFI 889
Q+ T ++SA+ EA + S +G G + + +YGP Q P +
Sbjct: 841 NQFDTEMLQAMILASAS---EAADGSSTLGGGAGTMGLSARYGPQFTLQHVP-DYRQNVY 896
Query: 890 IPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKK 928
IPGS A ++ + K+ G K+++ KK+KK
Sbjct: 897 IPGSNATLT---NAAGKRDGKAPAGGNGNKKKSGKKEKK 932
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.132 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,334,830
Number of Sequences: 37866
Number of extensions: 2061808
Number of successful extensions: 14941
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 214
Number of HSP's successfully gapped in prelim test: 77
Number of HSP's that attempted gapping in prelim test: 7462
Number of HSP's gapped (non-prelim): 1172
length of query: 950
length of database: 18,247,518
effective HSP length: 112
effective length of query: 838
effective length of database: 14,006,526
effective search space: 11737468788
effective search space used: 11737468788
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.