Search of human proteins with 9256576

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo
sapiens]
         (949 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo sapi...  1885   0.0  
gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo sap...  1570   0.0  
gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo sapi...  1521   0.0  
gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens]  1520   0.0  
gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens]  1510   0.0  
gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens]  1509   0.0  
gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens]  1509   0.0  
gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo sapi...  1505   0.0  
gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens]  1503   0.0  
gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo sapi...  1501   0.0  
gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens]  1495   0.0  
gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens]  1487   0.0  
gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens]  1487   0.0  
gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo sapi...  1470   0.0  
gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo sap...  1211   0.0  
gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo sapi...  1207   0.0  
gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo sapi...  1201   0.0  
gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo sapi...  1197   0.0  
gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo sapi...  1195   0.0  
gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo sap...  1193   0.0  
gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo sapi...  1189   0.0  
gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo sap...  1187   0.0  
gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo sapi...  1184   0.0  
gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo sapi...  1182   0.0  
gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapi...  1182   0.0  
gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens]  1157   0.0  
gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo sap...   790   0.0  
gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo sapi...   790   0.0  
gi|14165402 protocadherin alpha 1 isoform 3 precursor [Homo sapi...   788   0.0  
gi|14277675 protocadherin gamma subfamily C, 3 isoform 1 precurs...   605   e-173

>gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo
           sapiens]
          Length = 949

 Score = 1885 bits (4882), Expect = 0.0
 Identities = 949/949 (100%), Positives = 949/949 (100%)

Query: 1   MFGFQRRGLGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60
           MFGFQRRGLGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV
Sbjct: 1   MFGFQRRGLGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60

Query: 61  QRLFRVASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVN 120
           QRLFRVASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVN
Sbjct: 61  QRLFRVASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVN 120

Query: 121 VEVKDINDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSL 180
           VEVKDINDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSL
Sbjct: 121 VEVKDINDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSL 180

Query: 181 DSPTNGKQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDP 240
           DSPTNGKQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDP
Sbjct: 181 DSPTNGKQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDP 240

Query: 241 EFDKSEYKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMSIKPNGRHLFTLDQNNGE 300
           EFDKSEYKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMSIKPNGRHLFTLDQNNGE
Sbjct: 241 EFDKSEYKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMSIKPNGRHLFTLDQNNGE 300

Query: 301 VRVNGTLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVRE 360
           VRVNGTLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVRE
Sbjct: 301 VRVNGTLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVRE 360

Query: 361 DAQPSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAY 420
           DAQPSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAY
Sbjct: 361 DAQPSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAY 420

Query: 421 ELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARD 480
           ELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARD
Sbjct: 421 ELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARD 480

Query: 481 ADAQENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAG 540
           ADAQENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAG
Sbjct: 481 ADAQENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAG 540

Query: 541 VPPLSSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADS 600
           VPPLSSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADS
Sbjct: 541 VPPLSSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADS 600

Query: 601 GYNAWLSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTA 660
           GYNAWLSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTA
Sbjct: 601 GYNAWLSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTA 660

Query: 661 TATVLVSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTAL 720
           TATVLVSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTAL
Sbjct: 661 TATVLVSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTAL 720

Query: 721 WWSATPTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLN 780
           WWSATPTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLN
Sbjct: 721 WWSATPTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLN 780

Query: 781 KEEEGERQEPGSNHPGQPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPT 840
           KEEEGERQEPGSNHPGQPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPT
Sbjct: 781 KEEEGERQEPGSNHPGQPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPT 840

Query: 841 VSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQ 900
           VSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQ
Sbjct: 841 VSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQ 900

Query: 901 EPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 949
           EPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 901 EPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 949


>gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo
           sapiens]
          Length = 810

 Score = 1570 bits (4066), Expect = 0.0
 Identities = 797/797 (100%), Positives = 797/797 (100%)

Query: 1   MFGFQRRGLGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60
           MFGFQRRGLGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV
Sbjct: 1   MFGFQRRGLGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60

Query: 61  QRLFRVASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVN 120
           QRLFRVASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVN
Sbjct: 61  QRLFRVASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVN 120

Query: 121 VEVKDINDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSL 180
           VEVKDINDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSL
Sbjct: 121 VEVKDINDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSL 180

Query: 181 DSPTNGKQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDP 240
           DSPTNGKQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDP
Sbjct: 181 DSPTNGKQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDP 240

Query: 241 EFDKSEYKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMSIKPNGRHLFTLDQNNGE 300
           EFDKSEYKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMSIKPNGRHLFTLDQNNGE
Sbjct: 241 EFDKSEYKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMSIKPNGRHLFTLDQNNGE 300

Query: 301 VRVNGTLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVRE 360
           VRVNGTLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVRE
Sbjct: 301 VRVNGTLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVRE 360

Query: 361 DAQPSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAY 420
           DAQPSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAY
Sbjct: 361 DAQPSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAY 420

Query: 421 ELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARD 480
           ELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARD
Sbjct: 421 ELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARD 480

Query: 481 ADAQENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAG 540
           ADAQENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAG
Sbjct: 481 ADAQENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAG 540

Query: 541 VPPLSSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADS 600
           VPPLSSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADS
Sbjct: 541 VPPLSSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADS 600

Query: 601 GYNAWLSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTA 660
           GYNAWLSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTA
Sbjct: 601 GYNAWLSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTA 660

Query: 661 TATVLVSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTAL 720
           TATVLVSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTAL
Sbjct: 661 TATVLVSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTAL 720

Query: 721 WWSATPTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLN 780
           WWSATPTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLN
Sbjct: 721 WWSATPTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLN 780

Query: 781 KEEEGERQEPGSNHPGQ 797
           KEEEGERQEPGSNHPGQ
Sbjct: 781 KEEEGERQEPGSNHPGQ 797


>gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo
           sapiens]
          Length = 950

 Score = 1521 bits (3938), Expect = 0.0
 Identities = 770/944 (81%), Positives = 839/944 (88%), Gaps = 4/944 (0%)

Query: 10  GTPR---LQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRV 66
           G PR   L LWLL+L  WE GSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV RLFRV
Sbjct: 7   GGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRV 66

Query: 67  ASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDI 126
           ASK HGDLLEVNLQNGILFVNSRIDREELCG+SAECSIHLEVIVDRPLQVFHV V+V+DI
Sbjct: 67  ASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDI 126

Query: 127 NDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNG 186
           NDNPP+F   +++++IAES+  ++RFPL+GASDADI  N+ LTYRL  N+YF+LD+  + 
Sbjct: 127 NDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSL 186

Query: 187 KQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSE 246
           +Q+  LSL+L+K+LDRE+  E +LLLTA+DGGKPELTGTV+LL+ +LDVNDN PEF +S 
Sbjct: 187 EQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSV 246

Query: 247 YKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVNG 305
           YKV+++ENA   TLV+KLNATD D+G NG++ YS    + P   + FT++ NNGE+R  G
Sbjct: 247 YKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKG 306

Query: 306 TLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPS 365
            LD+EE K Y+I V+A DKG  PMAGHCT+ VE+LD NDN+PEV +TSLSLP+RED QPS
Sbjct: 307 KLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPS 366

Query: 366 TVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVT 425
            +IALISVSDRDSG NGQVTC+LTPHVPFKLVST+KNYYSLVLDSALDRE+V AYELVVT
Sbjct: 367 AIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVT 426

Query: 426 ARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQE 485
           ARDGGSPSLWATA VSV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA+DADAQE
Sbjct: 427 ARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQE 486

Query: 486 NALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLS 545
           NALVSYSLVERR+G+RALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD+GVPPL 
Sbjct: 487 NALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLG 546

Query: 546 SNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNAW 605
           SNVTLQVFVLDENDNAPALL   AGSAGG V++L+PRSVGAGHVVAKVRAVDADSGYNAW
Sbjct: 547 SNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAW 606

Query: 606 LSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVL 665
           LSYELQ AA G+RIPFRVGLYTGEISTTR LDE D+P HRLLVLVKDHGEPALTATATVL
Sbjct: 607 LSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVL 666

Query: 666 VSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSAT 725
           +SLVESGQAP+ASSR  AGA  PEAALVDVNVYLIIAIC VSSLLVLTLLLYTAL  SA 
Sbjct: 667 LSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAP 726

Query: 726 PTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNKEEEG 785
           PTEGACAPGKPTLVCS A GSWSYSQQRR RVCS EGP KTDLMAFSPSLP  L   E  
Sbjct: 727 PTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCLGSAEGT 786

Query: 786 ERQEPGSNHPGQPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSAT 845
            ++E  S    +PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSAT
Sbjct: 787 GQREEDSECLKEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSAT 846

Query: 846 PEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNS 905
           PEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNS
Sbjct: 847 PEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNS 906

Query: 906 QIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 949
           QIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 907 QIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950


>gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score = 1520 bits (3935), Expect = 0.0
 Identities = 773/945 (81%), Positives = 830/945 (87%), Gaps = 1/945 (0%)

Query: 6   RRGLGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFR 65
           R  LG+ RL L LLLL  W+VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV RLFR
Sbjct: 6   RGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFR 65

Query: 66  VASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKD 125
           VASK H DLLEV+LQNGILFVNSRIDREELCG+SAECSIHLEVIVDRPLQVFHV+VEVKD
Sbjct: 66  VASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKD 125

Query: 126 INDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTN 185
           +NDNPPVF +++QKL ++ES+  DSRFPLEGASDAD+  N++LTYRLS ++YF LD  + 
Sbjct: 126 VNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSK 185

Query: 186 GKQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKS 245
             + K + L+L+KSLDRE  P  +L LTATDGGKPELTGTV+LLV VLDVNDN P F++S
Sbjct: 186 NDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQS 245

Query: 246 EYKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVN 304
           EY+V + ENA   T V+KLNA+D DEG NG ++YS  S ++      F++D+N GE+ + 
Sbjct: 246 EYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIR 305

Query: 305 GTLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQP 364
           G LD+E+   YKI + ATDKG PPMAGHCTV V ILD NDN PE+A+TSLSLPVREDAQ 
Sbjct: 306 GNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQF 365

Query: 365 STVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVV 424
            TVIALISV+D DSG NGQVTCSL PHVPFKLVSTFKNYYSLVLDSALDRE V AYELVV
Sbjct: 366 GTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVV 425

Query: 425 TARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQ 484
           TARDGGSPSLWATA +SVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQ
Sbjct: 426 TARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQ 485

Query: 485 ENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL 544
           ENALVSYSLVERR+G+R+LSSY+SVH ESGKVYALQPLDHEELELLQFQVSARDAGVPPL
Sbjct: 486 ENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPL 545

Query: 545 SSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNA 604
            SNVTLQVFVLDENDNAPALL  + G  GGA +KLVPRSVGAGHVVAKVRAVDADSGYNA
Sbjct: 546 GSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNA 605

Query: 605 WLSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATV 664
           WLSYELQPAA   RIPFRVGLYTGEISTTR LDEADSPRHRLLVLVKDHGEPALTATATV
Sbjct: 606 WLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATV 665

Query: 665 LVSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSA 724
           LVSLVESGQAPKASSR  AG   PEAALVDVNVYLIIAIC VSSLLVLTLLLYTAL  SA
Sbjct: 666 LVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA 725

Query: 725 TPTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNKEEE 784
            PTEG C  GKPTLVCS AVGSWSYSQQ+ QRVCS EGPPKTDLMAFSP LP  L   + 
Sbjct: 726 LPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVDV 785

Query: 785 GERQEPGSNHPGQPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSA 844
           GE Q+   +H  +PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSA
Sbjct: 786 GEEQDLNVDHGLKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSA 845

Query: 845 TPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTN 904
           TPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTN
Sbjct: 846 TPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTN 905

Query: 905 SQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 949
           SQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 906 SQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950


>gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score = 1510 bits (3910), Expect = 0.0
 Identities = 772/945 (81%), Positives = 829/945 (87%), Gaps = 7/945 (0%)

Query: 9   LGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRVAS 68
           LG   L L LLLL  W+VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV RLFR+AS
Sbjct: 9   LGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMAS 68

Query: 69  KTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDIND 128
           K   DLLEVNLQNGILFVNSRIDREELCG+SAECSIHLEVIVDRPLQVFHV+VEV+DIND
Sbjct: 69  KDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDIND 128

Query: 129 NPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNGKQ 188
           NPP+F + EQ++LI ES+  DS FPLEGASDAD+  N++LTY+LS +EYF LD   N   
Sbjct: 129 NPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDD 188

Query: 189 IKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSEYK 248
            K++ L+LKKSLDRE+ P  NL LTATDGGKPELTGTV+LLV VLDVNDN P F++SEY+
Sbjct: 189 NKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248

Query: 249 VSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVNGTL 307
           V + ENA   T V++LNA+DRDEG NG ++YS  S +       F++D+N GE+ + G L
Sbjct: 249 VRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNL 308

Query: 308 DYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPSTV 367
           D+E+   YKI + ATDKG PPMAGHCTV V ILD NDN PE+A+TSLSLPVREDAQ  TV
Sbjct: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368

Query: 368 IALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVTAR 427
           IALISV+D DSG NGQV CSLTPHVPFKLVSTFKNYYSLVLDSALDRE+V AYELVVTAR
Sbjct: 369 IALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTAR 428

Query: 428 DGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 487
           DGGSPSLWATA +SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA
Sbjct: 429 DGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488

Query: 488 LVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLSSN 547
           LVSYSLVERR+G+RALSSY+SVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL SN
Sbjct: 489 LVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548

Query: 548 VTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNAWLS 607
           VTLQVFVLDENDNAPALLA + G  GGAV++LVPRS+GAG VVAKVRAVDADSGYNAWLS
Sbjct: 549 VTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLS 608

Query: 608 YELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVS 667
           YELQP A  +R PFRVGLYTGEISTTR LDEADSPRHRLLVLVKDHGEPALTATATVLVS
Sbjct: 609 YELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS 668

Query: 668 LVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSATPT 727
           LVESGQAPKASSR   GAA PEAALVDVNVYLIIAIC VSSLLVLTLLLYTAL  SA PT
Sbjct: 669 LVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728

Query: 728 EGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSL---PLGLNKEEE 784
           EGAC   KPTLVCS AVGSWSYSQQRRQRVCS EGPPK DLMAFSPSL   P+ + K   
Sbjct: 729 EGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGK--- 785

Query: 785 GERQEPGSNHPGQPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSA 844
            E Q+   +H  +PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSA
Sbjct: 786 AENQDLNEDHDAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSA 845

Query: 845 TPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTN 904
           TPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTN
Sbjct: 846 TPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTN 905

Query: 905 SQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 949
           SQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 906 SQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950


>gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score = 1509 bits (3908), Expect = 0.0
 Identities = 774/946 (81%), Positives = 829/946 (87%), Gaps = 1/946 (0%)

Query: 5   QRRGLGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLF 64
           +R GLG   L LWLLLL  WEVGSGQLHYS+ EEAKHGTFVGR+AQDLGLELAELV RLF
Sbjct: 5   RRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELVPRLF 64

Query: 65  RVASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVK 124
           RVASKTH DLLEVNLQNGILFVNSRIDREELC  SAECSIHLE+I DRPLQVFHV V+VK
Sbjct: 65  RVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVEVKVK 124

Query: 125 DINDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPT 184
           DINDNPPVF  REQ + I ES+  +SRFP+EGA+DADI  NALLTY LS ++YFSLD   
Sbjct: 125 DINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSLDVEA 184

Query: 185 NGKQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDK 244
           + +  K L L L+K LDRE+TPEL+LLLTATDGGKPEL GTV LL+ VLDVNDN P FD+
Sbjct: 185 SDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAPLFDQ 244

Query: 245 SEYKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRV 303
           + Y+V L+E  A  TLV  LNA+D DEGVNGEV +S  S I  + +  F +D ++GE+R+
Sbjct: 245 AVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSGEIRL 304

Query: 304 NGTLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQ 363
              LDYEE K Y+I+V+A DKG+PPM+ HC V V++LD NDN+PE+AVTSL LP+REDA 
Sbjct: 305 IDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIREDAP 364

Query: 364 PSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELV 423
            STVIALI+VSDRDSG NGQVTCSL PHVPFKLVSTFKNYYSLVLDSALDRE++  YELV
Sbjct: 365 LSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSVYELV 424

Query: 424 VTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADA 483
           VTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADA
Sbjct: 425 VTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADA 484

Query: 484 QENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPP 543
           QENALVSYSLVERR+G+RALS+YVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPP
Sbjct: 485 QENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPP 544

Query: 544 LSSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYN 603
           L SNVTLQVFVLDENDNAPALLA + G   GAV++LVPR VGAGHVVAKVRAVDADSGYN
Sbjct: 545 LGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDADSGYN 604

Query: 604 AWLSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATAT 663
           AWLSYELQPAAGG+RIPFRVGLYTGEISTTR LDEAD  R+RLLVLVKDHGEPALTATAT
Sbjct: 605 AWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALTATAT 664

Query: 664 VLVSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWS 723
           VLVSLVESGQAPKASSR   G A PEAALVDVNVYLIIAIC VSSLLVLTLLLYTAL  S
Sbjct: 665 VLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCS 724

Query: 724 ATPTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNKEE 783
             PTEGA  PGKPTLVCS A+GSWS SQQRRQRVCS EGPPKTDLMAFSP L   LN  E
Sbjct: 725 VPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSLNTSE 784

Query: 784 EGERQEPGSNHPGQPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSS 843
             E+ E   +  G PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSS
Sbjct: 785 RNEQPEANLDLSGNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSS 844

Query: 844 ATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPT 903
           ATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPT
Sbjct: 845 ATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPT 904

Query: 904 NSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 949
           NSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 905 NSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950


>gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens]
          Length = 947

 Score = 1509 bits (3907), Expect = 0.0
 Identities = 772/943 (81%), Positives = 831/943 (88%), Gaps = 4/943 (0%)

Query: 8   GLGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRVA 67
           G  + RL L LLLL  WE G+GQLHYSVSEEAKHGTFVGRIAQDLGLELAELV RLFRVA
Sbjct: 8   GQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67

Query: 68  SKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDIN 127
           SK  G LLEVNLQNGILFVNSRIDREELC +SAECSIHLEVIVDRPLQVFHV+VEV+DIN
Sbjct: 68  SKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDIN 127

Query: 128 DNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNGK 187
           DNPPVF   ++ L IAES+  DSRFPLEGASDADI ENALLTYRLS NEYFSL+ P + +
Sbjct: 128 DNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDE 187

Query: 188 QIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSEY 247
            +K L LIL+KSLDRE+ PE+ L+LTATDGGKPELTGTV+LL+ VLD NDN P FD++ Y
Sbjct: 188 LVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIY 247

Query: 248 KVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVNGT 306
           KV L+EN    TLV+KLNA+D DEG+NG++ YS  + I PN +  F +D   G++ V G 
Sbjct: 248 KVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGY 307

Query: 307 LDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPST 366
           +D+EE+K Y+I V+  DKG  P++GHC V VE+ D NDN P++   SLSLP+REDA   T
Sbjct: 308 IDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGT 367

Query: 367 VIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVTA 426
           VIALISVSD+D GVNG VTCSLT HVPFKLVSTFKNYYSLVLDSALDRE+V AYELVVTA
Sbjct: 368 VIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTA 427

Query: 427 RDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQEN 486
           RDGGSPSLWATA VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQEN
Sbjct: 428 RDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQEN 487

Query: 487 ALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLSS 546
           ALVSYSLVERR+G+RALSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARDAGVPPL S
Sbjct: 488 ALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGS 547

Query: 547 NVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNAWL 606
           NVTLQVFVLDENDNAPALLA +AG  GGAV++LVP SVG GHVVAKVRAVDADSGYNAWL
Sbjct: 548 NVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWL 607

Query: 607 SYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLV 666
           SYELQP  GG+RIPFRVGLYTGEISTTRALDE D+PRHRLLVLVKDHGEPALTATATVLV
Sbjct: 608 SYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLV 667

Query: 667 SLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSATP 726
           SLVESGQAPKASSR L GA  P+AALVDVNVYLIIAIC VSSLLVLTLLLYTAL  SA P
Sbjct: 668 SLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALP 727

Query: 727 TEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNKEEEGE 786
           TEGACAPGKPTLVCS AVGSWSYSQQRR RVCS EGPPKTDLMAFSPSLP   ++E++ +
Sbjct: 728 TEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSRDREDQLQ 787

Query: 787 RQEPGSNHPGQPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATP 846
             E       +PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATP
Sbjct: 788 TTEESF---AKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATP 844

Query: 847 EPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQ 906
           EPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQ
Sbjct: 845 EPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQ 904

Query: 907 IDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 949
           IDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 905 IDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 947


>gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo
           sapiens]
          Length = 941

 Score = 1505 bits (3896), Expect = 0.0
 Identities = 773/944 (81%), Positives = 826/944 (87%), Gaps = 10/944 (1%)

Query: 7   RGLGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRV 66
           RG G+ RL L LLLL  WEVGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV RLFRV
Sbjct: 7   RGPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRV 66

Query: 67  ASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDI 126
           ASK HGDLLEVNLQNGILFVNSRIDRE+LCG+SAECSIHLEVIVDRPLQVFHV+VEVKDI
Sbjct: 67  ASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDI 126

Query: 127 NDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNG 186
           NDNPPVF  REQK+ ++ES   DS FPLEGASDADI  N+LLTY LS NE F L   T  
Sbjct: 127 NDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKK 186

Query: 187 KQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSE 246
            +     L+L+K LDRE+TP+LNLLL   DGGKPELTG+V++ + VLDVNDN P FDK  
Sbjct: 187 DKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPS 246

Query: 247 YKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMSIKP-NGRHLFTLDQNNGEVRVNG 305
           YKV L EN   +T V++LNA+D DEG+NGE++Y +  I P + + +F+++ + GE+R+ G
Sbjct: 247 YKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYG 306

Query: 306 TLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPS 365
            LD+EEN  Y+I+V A DKG P MAGH  V VE+LD NDN PEV VTSLSLPV+EDAQ  
Sbjct: 307 ELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVG 366

Query: 366 TVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVT 425
           TVIALISVSDRDSG NGQV CSLTPHVPFKLVST+KNYYSLVLDSALDRE+V AYELVVT
Sbjct: 367 TVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVT 426

Query: 426 ARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQE 485
           ARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+
Sbjct: 427 ARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQK 486

Query: 486 NALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLS 545
           NALVSYSLVERR+G+ ALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL 
Sbjct: 487 NALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLG 546

Query: 546 SNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNAW 605
           SNVTLQVFVLDENDNAPALLAT AGSAGGAV++LVPRSVGAGHVVAKVRAVDADSGYNAW
Sbjct: 547 SNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAW 606

Query: 606 LSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVL 665
           LSYELQPAA G+ IPF VGLYTGEISTTR LDEAD+PRHRLLVLVKDHGEPALT+TATVL
Sbjct: 607 LSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVL 666

Query: 666 VSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSAT 725
           VSLVE+GQAPK SSR   GA  PEAALVD+NVYLIIAIC VSSLLVLTLLLYTAL  SA 
Sbjct: 667 VSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAP 726

Query: 726 PTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNKEEEG 785
           PT   CAPGKPTLVCS AVGSWSYSQQRRQRVCS E PPKTDLMAFSPSL L        
Sbjct: 727 PTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQLS------- 779

Query: 786 ERQEPGSNHPGQPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSAT 845
             +E   N P +PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSAT
Sbjct: 780 --REDCLNPPSEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSAT 837

Query: 846 PEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNS 905
           PEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNS
Sbjct: 838 PEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNS 897

Query: 906 QIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 949
           QIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 898 QIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 941


>gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens]
          Length = 948

 Score = 1503 bits (3891), Expect = 0.0
 Identities = 771/945 (81%), Positives = 831/945 (87%), Gaps = 3/945 (0%)

Query: 6   RRGLGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFR 65
           RRG G     L LLLL  WEVGSGQL YSV EEAKHGTFVGRIAQDLGLEL ELV RLFR
Sbjct: 6   RRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFR 65

Query: 66  VASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKD 125
           VASK HGDLLEVNLQNGILFVNSRIDREELCG+SAECSIH+EVIVDRPLQVFHV VEVKD
Sbjct: 66  VASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKD 125

Query: 126 INDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTN 185
           INDNPP+F +  + +   ES+  DSRFPLEGASDADI  NALL+Y+LS +E+F LD   N
Sbjct: 126 INDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQAN 185

Query: 186 GKQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKS 245
            +  + LSL+L KSLDRE+T E+NLLL ATDGGKPELTGTV++L++VLDVNDN+P F +S
Sbjct: 186 DELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQS 245

Query: 246 EYKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVN 304
            YKV L+EN A  TLV+KLNA+D DEG N E+ YSL S +    +  FT+D  +GE+R  
Sbjct: 246 VYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTK 305

Query: 305 GTLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQP 364
           G LDYEE K Y+I+V ATDKGTP M+GHC + ++++D NDN+PEV++TSLSLP+ E+A  
Sbjct: 306 GKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASL 365

Query: 365 STVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVV 424
            TVIALI+VSDRDSG NG VTCSLTPHVPFKLVSTFKNYYSLVLDSALDRE+V AYELVV
Sbjct: 366 GTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVV 425

Query: 425 TARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQ 484
           TARDGGSPSLWAT  VS+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ
Sbjct: 426 TARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQ 485

Query: 485 ENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL 544
           ENALVSYSLVERR+G+RALSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPL
Sbjct: 486 ENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPL 545

Query: 545 SSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNA 604
            SNVTLQVFVLDENDNAPALLA +AG+A GAV++LVP SVGAGHVVAKVRAVDADSGYNA
Sbjct: 546 GSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNA 605

Query: 605 WLSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATV 664
           WLSYELQ   G +RIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATV
Sbjct: 606 WLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATV 665

Query: 665 LVSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSA 724
           LVSLVESGQAPKASSR   GAA  EA LVDVNVYLIIAIC VSSLLVLT+LLYTAL  S 
Sbjct: 666 LVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSV 725

Query: 725 TPTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNKEEE 784
            PTEGA APGKPTLVCS AVGSWSYSQQRRQRVCS E PPKTDLMAFSPSL  G +  EE
Sbjct: 726 PPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAEE 785

Query: 785 GERQEPGSNHPGQPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSA 844
            +  E  S + G+PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSA
Sbjct: 786 KQLSE--SEYVGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSA 843

Query: 845 TPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTN 904
           TPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTN
Sbjct: 844 TPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTN 903

Query: 905 SQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 949
           SQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 904 SQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 948


>gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo
           sapiens]
          Length = 948

 Score = 1501 bits (3886), Expect = 0.0
 Identities = 773/942 (82%), Positives = 822/942 (87%), Gaps = 2/942 (0%)

Query: 9   LGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRVAS 68
           LG   L L LLLL  WEVGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELVQRLFRVAS
Sbjct: 8   LGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVAS 67

Query: 69  KTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDIND 128
           K HGDLLEVNLQNGILFVNSRIDREELCG+S ECSIHLEVIVDRPLQVFHV+VEVKDIND
Sbjct: 68  KRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDIND 127

Query: 129 NPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNGKQ 188
           NPP FS+ EQKL I ES+  DSRFPLEGASDAD+ ENALLTY+LS NEYF LD      +
Sbjct: 128 NPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDK 187

Query: 189 IKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSEYK 248
            K   L+L+K LDRE+ P+L LLLTATDGGKPE TG+V LL+ VLD NDN P FD+  Y+
Sbjct: 188 DKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYE 247

Query: 249 VSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVNGTL 307
           V + EN   +TLV++LNA+D DEG+N E+ YS  S + P  R  F +++  GE++VN  +
Sbjct: 248 VKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAI 307

Query: 308 DYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPSTV 367
           D+E++  Y+I V  TDKG PPM GHCTV VE+LD NDNSPEV VTSLSLPV+EDAQ  TV
Sbjct: 308 DFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTV 367

Query: 368 IALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVTAR 427
           IALISVSD DSG NGQVTCSLTPHVPFKLVST+KNYYSLVLDSALDRE V AYELVVTAR
Sbjct: 368 IALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTAR 427

Query: 428 DGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 487
           DGGSP LWATA VSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQENA
Sbjct: 428 DGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENA 487

Query: 488 LVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLSSN 547
           LVSYSLVERRLG+R+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD GVPPL SN
Sbjct: 488 LVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSN 547

Query: 548 VTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNAWLS 607
           +TLQVFVLDENDNAPALLA+ AGSAGGAV++LV RSV AGHVVAKVRAVDADSGYNAWLS
Sbjct: 548 LTLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLS 607

Query: 608 YELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVS 667
           YELQ AA G+RIPFRVGLYTGEISTTRALDE DSPR RLLVLVKDHGEP+LTATATVLVS
Sbjct: 608 YELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVS 667

Query: 668 LVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSATPT 727
           LVE  QAPKASSR   G A PE ALVDVNVYLIIAIC VSSLLVLTLLLYTAL  SA PT
Sbjct: 668 LVEGSQAPKASSRASVGVA-PEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPT 726

Query: 728 EGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNKEEEGER 787
           EGAC P KPTLVCS AVGSWSYSQQRRQRVCS EG PK DLMAFSPSLP     + +GE 
Sbjct: 727 EGACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCPMVDVDGED 786

Query: 788 QEPGSNHPGQPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPE 847
           Q  G +H  +PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPE
Sbjct: 787 QSIGGDHSRKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPE 846

Query: 848 PEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQI 907
           PEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQI
Sbjct: 847 PEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQI 906

Query: 908 DKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 949
           DKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 907 DKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 948


>gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score = 1495 bits (3871), Expect = 0.0
 Identities = 767/945 (81%), Positives = 826/945 (87%), Gaps = 1/945 (0%)

Query: 6   RRGLGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFR 65
           R   G   L L LLLL   EVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV RLFR
Sbjct: 6   REDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFR 65

Query: 66  VASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKD 125
           VASK HGDLLEVNLQNGILFVNSRIDREELCG+SAECSIHLEVIVDRPLQVFHV VEVKD
Sbjct: 66  VASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKD 125

Query: 126 INDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTN 185
           INDN PVF +  + L I+ES+Q  SRF LEGASDADI  N+LLTY L   EYF+LD   N
Sbjct: 126 INDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRN 185

Query: 186 GKQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKS 245
            ++IK L L+LKK+L+RE TP+  LL+TA DGGKPELTGT +L + VLDVNDN P F+++
Sbjct: 186 DEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERT 245

Query: 246 EYKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVN 304
            YKV L+ENA   TLV+ +NATD DEGVN ++ YS  + +  +    F LD  NG++ V 
Sbjct: 246 IYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVK 305

Query: 305 GTLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQP 364
           G +D+EE+K Y+I+V+ATDKG PPM+ HCTV +EI+D NDN PE+ + SLSLPV ED+  
Sbjct: 306 GNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSPL 365

Query: 365 STVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVV 424
           STVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDS LDRE+V AYELVV
Sbjct: 366 STVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVV 425

Query: 425 TARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQ 484
           TARDGGSPSLWATA VSVEVADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSARDADAQ
Sbjct: 426 TARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADAQ 485

Query: 485 ENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL 544
           ENALVSYSLVERR+G+RALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL
Sbjct: 486 ENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL 545

Query: 545 SSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNA 604
            SNVTLQVFVLDENDNAPALL  + G  GGAV++LVPRSVGAGHVVAKVRAVDADSGYNA
Sbjct: 546 GSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYNA 605

Query: 605 WLSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATV 664
           WLSYELQP  GG+RIPFRVGLYTGEISTTRALDE D+PRHRLLVLVKDHGEP+LTATATV
Sbjct: 606 WLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLTATATV 665

Query: 665 LVSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSA 724
           LVSLVESGQAPKASS+  AGA  PEAALVDVNVYLI+AIC VSSLLVLTLLLYTAL  SA
Sbjct: 666 LVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTALRCSA 725

Query: 725 TPTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNKEEE 784
            PTEG C PGKPTLVCS AVGSWSYSQQR+QRVCS EG PKTDLMAFSPSLP      + 
Sbjct: 726 PPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCPISRDR 785

Query: 785 GERQEPGSNHPGQPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSA 844
            E+Q+   +   +PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSA
Sbjct: 786 EEKQDVDVDLSAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSA 845

Query: 845 TPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTN 904
           TPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTN
Sbjct: 846 TPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTN 905

Query: 905 SQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 949
           SQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 906 SQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950


>gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens]
          Length = 937

 Score = 1487 bits (3850), Expect = 0.0
 Identities = 761/941 (80%), Positives = 820/941 (87%), Gaps = 14/941 (1%)

Query: 10  GTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRVASK 69
           G   L L++++L  WE G GQLHYSV EEAKHG FVGRIAQDLGLELAELV RLFR   K
Sbjct: 10  GGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCK 69

Query: 70  THGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDINDN 129
             GDLLEVNLQNGILFVNSRIDREELCG+SAECSIHLEVIV+RPLQVFHV+VEVKDINDN
Sbjct: 70  FRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDN 129

Query: 130 PPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNGKQI 189
           PPVF   ++ L IAES+  DSRFPLEGASDADI ENALLTYRLS NEYF LD PT+ +Q+
Sbjct: 130 PPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQV 189

Query: 190 KRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSEYKV 249
           K L L+L+K LDRE+TPEL+LLLTATDGGKPELTGTV+LL+ VLD NDN P FD++ Y V
Sbjct: 190 KPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTV 249

Query: 250 SLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVNGTLD 308
            L EN +  TLV+  NA+D DEG+NG++ YS  S + P+ +  F +D  +G + V G +D
Sbjct: 250 KLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMD 309

Query: 309 YEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPSTVI 368
           +EE++ +KI V+A DKG PP+AGHCTV VE++D NDN+P++ +TSLSLP+ EDAQP TVI
Sbjct: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369

Query: 369 ALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVTARD 428
            LISV DRD GVNGQVTCSLTP VPFKLVSTFKNYYSLVLDSALDRE+V AYELVVTARD
Sbjct: 370 TLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429

Query: 429 GGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 488
           GGSPSLWATA VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL
Sbjct: 430 GGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNAL 489

Query: 489 VSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLSSNV 548
           VSYSLVE R+G+RALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL SNV
Sbjct: 490 VSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549

Query: 549 TLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNAWLSY 608
           TLQVFVLDENDNAPALLA + G  GGAV +LVPRSVGAGHVVAKVRAVDADSGYNAWLSY
Sbjct: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609

Query: 609 ELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSL 668
           ELQP A G+ IPFRVGLYTGEISTTRALDE D+PRHRLLVLVKDHGEP+LTATATVLVSL
Sbjct: 610 ELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSL 669

Query: 669 VESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSATPTE 728
           VESGQAPKASSR   G A PE  LVDVNVYLIIAIC VSSLLVLTLLLYTAL  SA  +E
Sbjct: 670 VESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSE 729

Query: 729 GACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNKEEEGERQ 788
           GAC+  KPTLVCS AVGSWS+SQQRRQRVCS EGPPKTDLMAFSPSLP G          
Sbjct: 730 GACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQG---------- 779

Query: 789 EPGSNHPGQPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 848
            P S     PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP
Sbjct: 780 -PSST--DNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 836

Query: 849 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 908
           EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID
Sbjct: 837 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 896

Query: 909 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 949
           KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 897 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 937


>gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens]
          Length = 936

 Score = 1487 bits (3849), Expect = 0.0
 Identities = 761/948 (80%), Positives = 818/948 (86%), Gaps = 16/948 (1%)

Query: 4   FQRRG-LGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQR 62
           + RRG LG+  L LWLLL  +W+ GSGQLHYS+ EEAKHGTFVGRIAQDLGLELAELV R
Sbjct: 3   YSRRGSLGSRLLLLWLLLA-YWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPR 61

Query: 63  LFRVASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVE 122
           LFRVASK  GDLLEVNLQNGILFVNSRIDREELC + AECSIHLEVIVDRPLQVFHV V 
Sbjct: 62  LFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVA 121

Query: 123 VKDINDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDS 182
           VKDINDNPP FS +EQ+L I ES+  DSRFPLEGASD DI  NA L YRL+ NEYF LD 
Sbjct: 122 VKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDV 181

Query: 183 PTNGKQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEF 242
            TN ++   L L+L+KSLDRE+T E  LL+ ATDGGKPELTGTV+LL+ VLD NDN PEF
Sbjct: 182 KTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEF 241

Query: 243 DKSEYKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEV 301
           DKS Y V L+ENA   TLV+KLNA+D DEG+N E+ Y   + +  + +  F ++ N GE+
Sbjct: 242 DKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEI 301

Query: 302 RVNGTLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVRED 361
           +VNG LDYE+   Y+I + A DK T P++GHC V V++LD NDN+PE+A+T+L LPV+ED
Sbjct: 302 KVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKED 361

Query: 362 AQPSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYE 421
           A  STVIALISVSDRDSG NGQVTCSL PHVPFKLVSTFKNYYSLVLDSALDRE+V  YE
Sbjct: 362 APLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYE 421

Query: 422 LVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDA 481
           LVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSARDA
Sbjct: 422 LVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDA 481

Query: 482 DAQENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGV 541
           DAQENALVSYSLVERR+G+R LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGV
Sbjct: 482 DAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGV 541

Query: 542 PPLSSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSG 601
           PPL SNVTLQVFVLDENDNAPALL  + G  GGAV++LVPRSVGAGHVVAKVRAVD DSG
Sbjct: 542 PPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSG 601

Query: 602 YNAWLSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTAT 661
           YNAWLSYELQPA G +RIPFRVGLYTGEISTTR+LDE ++PRHRLLVLVKDHGEP LTAT
Sbjct: 602 YNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTAT 661

Query: 662 ATVLVSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALW 721
           ATVLVSLVESGQAPKASSR  AGA  PEAALVDVNVYLIIAIC VSSLLVLTLLLYTAL 
Sbjct: 662 ATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALR 721

Query: 722 WSATPTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNK 781
            SA PTE  C  GKPTL+CS AVGSWSYSQQRRQRVCS E PPKTDLMAFSPSLP G   
Sbjct: 722 CSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPTS 781

Query: 782 EEEGERQEPGSNHPGQPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTV 841
            +              PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTV
Sbjct: 782 TD-------------NPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTV 828

Query: 842 SSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQE 901
           SSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQE
Sbjct: 829 SSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQE 888

Query: 902 PTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 949
           PTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 889 PTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 936


>gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo
           sapiens]
          Length = 950

 Score = 1470 bits (3806), Expect = 0.0
 Identities = 753/938 (80%), Positives = 817/938 (87%), Gaps = 3/938 (0%)

Query: 14  LQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRVASKTHGD 73
           L L LL+L  W VGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLF++ SK  GD
Sbjct: 14  LLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGRGD 73

Query: 74  LLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDINDNPPVF 133
           LLEVNLQNGILFVNSRIDREELCG+SAECSIHLEVIVDRPLQVFHV+VEVKDINDNPPVF
Sbjct: 74  LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPPVF 133

Query: 134 SLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNGKQIKRLS 193
              ++ L IAES+  DSRFPLEGASDADI ENALLTYRLS NEYF LD PT+ +Q+K L 
Sbjct: 134 PATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLG 193

Query: 194 LILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSEYKVSLME 253
           L+L+K LDRE+TPEL+LLLTATDGGKPELTGTV+LL+ VLD NDN P FD++ Y V L E
Sbjct: 194 LVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPE 253

Query: 254 NAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVNGTLDYEEN 312
           N +  TLV+  NA+D DEG+NG++ YS  S + P+ +  F +D  +G + V G +D+EE+
Sbjct: 254 NVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEES 313

Query: 313 KFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPSTVIALIS 372
           + +KI V+A DKG PP+AGHCT+ VE++D NDN+P++ + +LS+PV+EDAQ  TVIALIS
Sbjct: 314 RAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIALIS 373

Query: 373 VSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVTARDGGSP 432
           V D D+  NGQVTCSLTPHVPFKLVST+KNYYSLVLD ALDRE+V AYELVVTARDGGSP
Sbjct: 374 VIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGGSP 433

Query: 433 SLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYS 492
           SLWATARVSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSARDADAQENALVSYS
Sbjct: 434 SLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYS 493

Query: 493 LVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLSSNVTLQV 552
           LVERRLG+R+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL SNVTLQV
Sbjct: 494 LVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQV 553

Query: 553 FVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQP 612
           FVLDENDNAPALL  +     GAV+++V RSVGAG VV KVRAVDADSGYNAWLSYELQP
Sbjct: 554 FVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLSYELQP 613

Query: 613 AAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESG 672
               + IPFRVGLYTGEISTTRALDE D+PR RLLVLVKDHGEPALTATATVLVSLVESG
Sbjct: 614 ETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVSLVESG 673

Query: 673 QAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSATPTEGACA 732
           QAPK+SSR   GA  PE  LVDVNVYLIIAIC VSSLLVLTLLLYT L  SA PTEG CA
Sbjct: 674 QAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMPTEGECA 733

Query: 733 PGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSL-PLGLNKEEEGERQEPG 791
           PGKPTLVCS AVGSWSYSQQRRQRVCS EG  KTDLMAFSP L P   + E  GE     
Sbjct: 734 PGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCAGSTERTGE-PSAS 792

Query: 792 SNHPGQPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAG 851
           S+  G+PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAG
Sbjct: 793 SDSTGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAG 852

Query: 852 EVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSD 911
           EVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSD
Sbjct: 853 EVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSD 912

Query: 912 FITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 949
           FITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 913 FITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950


>gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo
           sapiens]
          Length = 807

 Score = 1211 bits (3132), Expect = 0.0
 Identities = 619/785 (78%), Positives = 687/785 (87%), Gaps = 5/785 (0%)

Query: 10  GTPR---LQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRV 66
           G PR   L LWLL+L  WE GSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV RLFRV
Sbjct: 7   GGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRV 66

Query: 67  ASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDI 126
           ASK HGDLLEVNLQNGILFVNSRIDREELCG+SAECSIHLEVIVDRPLQVFHV V+V+DI
Sbjct: 67  ASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDI 126

Query: 127 NDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNG 186
           NDNPP+F   +++++IAES+  ++RFPL+GASDADI  N+ LTYRL  N+YF+LD+  + 
Sbjct: 127 NDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSL 186

Query: 187 KQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSE 246
           +Q+  LSL+L+K+LDRE+  E +LLLTA+DGGKPELTGTV+LL+ +LDVNDN PEF +S 
Sbjct: 187 EQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSV 246

Query: 247 YKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVNG 305
           YKV+++ENA   TLV+KLNATD D+G NG++ YS    + P   + FT++ NNGE+R  G
Sbjct: 247 YKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKG 306

Query: 306 TLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPS 365
            LD+EE K Y+I V+A DKG  PMAGHCT+ VE+LD NDN+PEV +TSLSLP+RED QPS
Sbjct: 307 KLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPS 366

Query: 366 TVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVT 425
            +IALISVSDRDSG NGQVTC+LTPHVPFKLVST+KNYYSLVLDSALDRE+V AYELVVT
Sbjct: 367 AIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVT 426

Query: 426 ARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQE 485
           ARDGGSPSLWATA VSV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA+DADAQE
Sbjct: 427 ARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQE 486

Query: 486 NALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLS 545
           NALVSYSLVERR+G+RALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD+GVPPL 
Sbjct: 487 NALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLG 546

Query: 546 SNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNAW 605
           SNVTLQVFVLDENDNAPALL   AGSAGG V++L+PRSVGAGHVVAKVRAVDADSGYNAW
Sbjct: 547 SNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAW 606

Query: 606 LSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVL 665
           LSYELQ AA G+RIPFRVGLYTGEISTTR LDE D+P HRLLVLVKDHGEPALTATATVL
Sbjct: 607 LSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVL 666

Query: 666 VSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSAT 725
           +SLVESGQAP+ASSR  AGA  PEAALVDVNVYLIIAIC VSSLLVLTLLLYTAL  SA 
Sbjct: 667 LSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAP 726

Query: 726 PTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNKEE-E 784
           PTEGACAPGKPTLVCS A GSWSYSQQRR RVCS EGP KTDLMAFSPSLP  L   E  
Sbjct: 727 PTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCLGSAEGT 786

Query: 785 GERQE 789
           G+R+E
Sbjct: 787 GQREE 791


>gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo
           sapiens]
          Length = 814

 Score = 1207 bits (3124), Expect = 0.0
 Identities = 621/790 (78%), Positives = 677/790 (85%), Gaps = 1/790 (0%)

Query: 6   RRGLGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFR 65
           R  LG+ RL L LLLL  W+VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV RLFR
Sbjct: 6   RGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFR 65

Query: 66  VASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKD 125
           VASK H DLLEV+LQNGILFVNSRIDREELCG+SAECSIHLEVIVDRPLQVFHV+VEVKD
Sbjct: 66  VASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKD 125

Query: 126 INDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTN 185
           +NDNPPVF +++QKL ++ES+  DSRFPLEGASDAD+  N++LTYRLS ++YF LD  + 
Sbjct: 126 VNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSK 185

Query: 186 GKQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKS 245
             + K + L+L+KSLDRE  P  +L LTATDGGKPELTGTV+LLV VLDVNDN P F++S
Sbjct: 186 NDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQS 245

Query: 246 EYKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVN 304
           EY+V + ENA   T V+KLNA+D DEG NG ++YS  S ++      F++D+N GE+ + 
Sbjct: 246 EYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIR 305

Query: 305 GTLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQP 364
           G LD+E+   YKI + ATDKG PPMAGHCTV V ILD NDN PE+A+TSLSLPVREDAQ 
Sbjct: 306 GNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQF 365

Query: 365 STVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVV 424
            TVIALISV+D DSG NGQVTCSL PHVPFKLVSTFKNYYSLVLDSALDRE V AYELVV
Sbjct: 366 GTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVV 425

Query: 425 TARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQ 484
           TARDGGSPSLWATA +SVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQ
Sbjct: 426 TARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQ 485

Query: 485 ENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL 544
           ENALVSYSLVERR+G+R+LSSY+SVH ESGKVYALQPLDHEELELLQFQVSARDAGVPPL
Sbjct: 486 ENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPL 545

Query: 545 SSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNA 604
            SNVTLQVFVLDENDNAPALL  + G  GGA +KLVPRSVGAGHVVAKVRAVDADSGYNA
Sbjct: 546 GSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNA 605

Query: 605 WLSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATV 664
           WLSYELQPAA   RIPFRVGLYTGEISTTR LDEADSPRHRLLVLVKDHGEPALTATATV
Sbjct: 606 WLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATV 665

Query: 665 LVSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSA 724
           LVSLVESGQAPKASSR  AG   PEAALVDVNVYLIIAIC VSSLLVLTLLLYTAL  SA
Sbjct: 666 LVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA 725

Query: 725 TPTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNKEEE 784
            PTEG C  GKPTLVCS AVGSWSYSQQ+ QRVCS EGPPKTDLMAFSP LP  L   + 
Sbjct: 726 LPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVDV 785

Query: 785 GERQEPGSNH 794
           GE Q+   +H
Sbjct: 786 GEEQDLNVDH 795


>gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo
           sapiens]
          Length = 798

 Score = 1201 bits (3107), Expect = 0.0
 Identities = 620/783 (79%), Positives = 678/783 (86%), Gaps = 1/783 (0%)

Query: 8   GLGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRVA 67
           G  + RL L LLLL  WE G+GQLHYSVSEEAKHGTFVGRIAQDLGLELAELV RLFRVA
Sbjct: 8   GQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67

Query: 68  SKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDIN 127
           SK  G LLEVNLQNGILFVNSRIDREELC +SAECSIHLEVIVDRPLQVFHV+VEV+DIN
Sbjct: 68  SKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDIN 127

Query: 128 DNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNGK 187
           DNPPVF   ++ L IAES+  DSRFPLEGASDADI ENALLTYRLS NEYFSL+ P + +
Sbjct: 128 DNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDE 187

Query: 188 QIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSEY 247
            +K L LIL+KSLDRE+ PE+ L+LTATDGGKPELTGTV+LL+ VLD NDN P FD++ Y
Sbjct: 188 LVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIY 247

Query: 248 KVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVNGT 306
           KV L+EN    TLV+KLNA+D DEG+NG++ YS  + I PN +  F +D   G++ V G 
Sbjct: 248 KVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGY 307

Query: 307 LDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPST 366
           +D+EE+K Y+I V+  DKG  P++GHC V VE+ D NDN P++   SLSLP+REDA   T
Sbjct: 308 IDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGT 367

Query: 367 VIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVTA 426
           VIALISVSD+D GVNG VTCSLT HVPFKLVSTFKNYYSLVLDSALDRE+V AYELVVTA
Sbjct: 368 VIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTA 427

Query: 427 RDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQEN 486
           RDGGSPSLWATA VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQEN
Sbjct: 428 RDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQEN 487

Query: 487 ALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLSS 546
           ALVSYSLVERR+G+RALSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARDAGVPPL S
Sbjct: 488 ALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGS 547

Query: 547 NVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNAWL 606
           NVTLQVFVLDENDNAPALLA +AG  GGAV++LVP SVG GHVVAKVRAVDADSGYNAWL
Sbjct: 548 NVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWL 607

Query: 607 SYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLV 666
           SYELQP  GG+RIPFRVGLYTGEISTTRALDE D+PRHRLLVLVKDHGEPALTATATVLV
Sbjct: 608 SYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLV 667

Query: 667 SLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSATP 726
           SLVESGQAPKASSR L GA  P+AALVDVNVYLIIAIC VSSLLVLTLLLYTAL  SA P
Sbjct: 668 SLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALP 727

Query: 727 TEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNKEEEGE 786
           TEGACAPGKPTLVCS AVGSWSYSQQRR RVCS EGPPKTDLMAFSPSLP   ++E++ +
Sbjct: 728 TEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSRDREDQLQ 787

Query: 787 RQE 789
             E
Sbjct: 788 TTE 790


>gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo
           sapiens]
          Length = 803

 Score = 1197 bits (3097), Expect = 0.0
 Identities = 619/785 (78%), Positives = 674/785 (85%), Gaps = 4/785 (0%)

Query: 9   LGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRVAS 68
           LG   L L LLLL  W+VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV RLFR+AS
Sbjct: 9   LGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMAS 68

Query: 69  KTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDIND 128
           K   DLLEVNLQNGILFVNSRIDREELCG+SAECSIHLEVIVDRPLQVFHV+VEV+DIND
Sbjct: 69  KDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDIND 128

Query: 129 NPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNGKQ 188
           NPP+F + EQ++LI ES+  DS FPLEGASDAD+  N++LTY+LS +EYF LD   N   
Sbjct: 129 NPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDD 188

Query: 189 IKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSEYK 248
            K++ L+LKKSLDRE+ P  NL LTATDGGKPELTGTV+LLV VLDVNDN P F++SEY+
Sbjct: 189 NKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248

Query: 249 VSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVNGTL 307
           V + ENA   T V++LNA+DRDEG NG ++YS  S +       F++D+N GE+ + G L
Sbjct: 249 VRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNL 308

Query: 308 DYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPSTV 367
           D+E+   YKI + ATDKG PPMAGHCTV V ILD NDN PE+A+TSLSLPVREDAQ  TV
Sbjct: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368

Query: 368 IALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVTAR 427
           IALISV+D DSG NGQV CSLTPHVPFKLVSTFKNYYSLVLDSALDRE+V AYELVVTAR
Sbjct: 369 IALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTAR 428

Query: 428 DGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 487
           DGGSPSLWATA +SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA
Sbjct: 429 DGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488

Query: 488 LVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLSSN 547
           LVSYSLVERR+G+RALSSY+SVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL SN
Sbjct: 489 LVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548

Query: 548 VTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNAWLS 607
           VTLQVFVLDENDNAPALLA + G  GGAV++LVPRS+GAG VVAKVRAVDADSGYNAWLS
Sbjct: 549 VTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLS 608

Query: 608 YELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVS 667
           YELQP A  +R PFRVGLYTGEISTTR LDEADSPRHRLLVLVKDHGEPALTATATVLVS
Sbjct: 609 YELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS 668

Query: 668 LVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSATPT 727
           LVESGQAPKASSR   GAA PEAALVDVNVYLIIAIC VSSLLVLTLLLYTAL  SA PT
Sbjct: 669 LVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728

Query: 728 EGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSL---PLGLNKEEE 784
           EGAC   KPTLVCS AVGSWSYSQQRRQRVCS EGPPK DLMAFSPSL   P+ + K E 
Sbjct: 729 EGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAEN 788

Query: 785 GERQE 789
            +  E
Sbjct: 789 QDLNE 793


>gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 807

 Score = 1195 bits (3092), Expect = 0.0
 Identities = 621/786 (79%), Positives = 675/786 (85%), Gaps = 1/786 (0%)

Query: 5   QRRGLGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLF 64
           +R GLG   L LWLLLL  WEVGSGQLHYS+ EEAKHGTFVGR+AQDLGLELAELV RLF
Sbjct: 5   RRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELVPRLF 64

Query: 65  RVASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVK 124
           RVASKTH DLLEVNLQNGILFVNSRIDREELC  SAECSIHLE+I DRPLQVFHV V+VK
Sbjct: 65  RVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVEVKVK 124

Query: 125 DINDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPT 184
           DINDNPPVF  REQ + I ES+  +SRFP+EGA+DADI  NALLTY LS ++YFSLD   
Sbjct: 125 DINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSLDVEA 184

Query: 185 NGKQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDK 244
           + +  K L L L+K LDRE+TPEL+LLLTATDGGKPEL GTV LL+ VLDVNDN P FD+
Sbjct: 185 SDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAPLFDQ 244

Query: 245 SEYKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRV 303
           + Y+V L+E  A  TLV  LNA+D DEGVNGEV +S  S I  + +  F +D ++GE+R+
Sbjct: 245 AVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSGEIRL 304

Query: 304 NGTLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQ 363
              LDYEE K Y+I+V+A DKG+PPM+ HC V V++LD NDN+PE+AVTSL LP+REDA 
Sbjct: 305 IDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIREDAP 364

Query: 364 PSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELV 423
            STVIALI+VSDRDSG NGQVTCSL PHVPFKLVSTFKNYYSLVLDSALDRE++  YELV
Sbjct: 365 LSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSVYELV 424

Query: 424 VTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADA 483
           VTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADA
Sbjct: 425 VTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADA 484

Query: 484 QENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPP 543
           QENALVSYSLVERR+G+RALS+YVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPP
Sbjct: 485 QENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPP 544

Query: 544 LSSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYN 603
           L SNVTLQVFVLDENDNAPALLA + G   GAV++LVPR VGAGHVVAKVRAVDADSGYN
Sbjct: 545 LGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDADSGYN 604

Query: 604 AWLSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATAT 663
           AWLSYELQPAAGG+RIPFRVGLYTGEISTTR LDEAD  R+RLLVLVKDHGEPALTATAT
Sbjct: 605 AWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALTATAT 664

Query: 664 VLVSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWS 723
           VLVSLVESGQAPKASSR   G A PEAALVDVNVYLIIAIC VSSLLVLTLLLYTAL  S
Sbjct: 665 VLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCS 724

Query: 724 ATPTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNKEE 783
             PTEGA  PGKPTLVCS A+GSWS SQQRRQRVCS EGPPKTDLMAFSP L   LN  E
Sbjct: 725 VPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSLNTSE 784

Query: 784 EGERQE 789
             E+ E
Sbjct: 785 RNEQPE 790


>gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo
           sapiens]
          Length = 792

 Score = 1193 bits (3087), Expect = 0.0
 Identities = 618/772 (80%), Positives = 669/772 (86%), Gaps = 1/772 (0%)

Query: 7   RGLGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRV 66
           RG G+ RL L LLLL  WEVGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV RLFRV
Sbjct: 7   RGPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRV 66

Query: 67  ASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDI 126
           ASK HGDLLEVNLQNGILFVNSRIDRE+LCG+SAECSIHLEVIVDRPLQVFHV+VEVKDI
Sbjct: 67  ASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDI 126

Query: 127 NDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNG 186
           NDNPPVF  REQK+ ++ES   DS FPLEGASDADI  N+LLTY LS NE F L   T  
Sbjct: 127 NDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKK 186

Query: 187 KQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSE 246
            +     L+L+K LDRE+TP+LNLLL   DGGKPELTG+V++ + VLDVNDN P FDK  
Sbjct: 187 DKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPS 246

Query: 247 YKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMSIKP-NGRHLFTLDQNNGEVRVNG 305
           YKV L EN   +T V++LNA+D DEG+NGE++Y +  I P + + +F+++ + GE+R+ G
Sbjct: 247 YKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYG 306

Query: 306 TLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPS 365
            LD+EEN  Y+I+V A DKG P MAGH  V VE+LD NDN PEV VTSLSLPV+EDAQ  
Sbjct: 307 ELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVG 366

Query: 366 TVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVT 425
           TVIALISVSDRDSG NGQV CSLTPHVPFKLVST+KNYYSLVLDSALDRE+V AYELVVT
Sbjct: 367 TVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVT 426

Query: 426 ARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQE 485
           ARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+
Sbjct: 427 ARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQK 486

Query: 486 NALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLS 545
           NALVSYSLVERR+G+ ALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL 
Sbjct: 487 NALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLG 546

Query: 546 SNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNAW 605
           SNVTLQVFVLDENDNAPALLAT AGSAGGAV++LVPRSVGAGHVVAKVRAVDADSGYNAW
Sbjct: 547 SNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAW 606

Query: 606 LSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVL 665
           LSYELQPAA G+ IPF VGLYTGEISTTR LDEAD+PRHRLLVLVKDHGEPALT+TATVL
Sbjct: 607 LSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVL 666

Query: 666 VSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSAT 725
           VSLVE+GQAPK SSR   GA  PEAALVD+NVYLIIAIC VSSLLVLTLLLYTAL  SA 
Sbjct: 667 VSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAP 726

Query: 726 PTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPL 777
           PT   CAPGKPTLVCS AVGSWSYSQQRRQRVCS E PPKTDLMAFSPSL L
Sbjct: 727 PTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQL 778


>gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo
           sapiens]
          Length = 824

 Score = 1189 bits (3077), Expect = 0.0
 Identities = 617/785 (78%), Positives = 675/785 (85%), Gaps = 1/785 (0%)

Query: 6   RRGLGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFR 65
           RRG G     L LLLL  WEVGSGQL YSV EEAKHGTFVGRIAQDLGLEL ELV RLFR
Sbjct: 6   RRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFR 65

Query: 66  VASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKD 125
           VASK HGDLLEVNLQNGILFVNSRIDREELCG+SAECSIH+EVIVDRPLQVFHV VEVKD
Sbjct: 66  VASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKD 125

Query: 126 INDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTN 185
           INDNPP+F +  + +   ES+  DSRFPLEGASDADI  NALL+Y+LS +E+F LD   N
Sbjct: 126 INDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQAN 185

Query: 186 GKQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKS 245
            +  + LSL+L KSLDRE+T E+NLLL ATDGGKPELTGTV++L++VLDVNDN+P F +S
Sbjct: 186 DELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQS 245

Query: 246 EYKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVN 304
            YKV L+EN A  TLV+KLNA+D DEG N E+ YSL S +    +  FT+D  +GE+R  
Sbjct: 246 VYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTK 305

Query: 305 GTLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQP 364
           G LDYEE K Y+I+V ATDKGTP M+GHC + ++++D NDN+PEV++TSLSLP+ E+A  
Sbjct: 306 GKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASL 365

Query: 365 STVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVV 424
            TVIALI+VSDRDSG NG VTCSLTPHVPFKLVSTFKNYYSLVLDSALDRE+V AYELVV
Sbjct: 366 GTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVV 425

Query: 425 TARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQ 484
           TARDGGSPSLWAT  VS+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ
Sbjct: 426 TARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQ 485

Query: 485 ENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL 544
           ENALVSYSLVERR+G+RALSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPL
Sbjct: 486 ENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPL 545

Query: 545 SSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNA 604
            SNVTLQVFVLDENDNAPALLA +AG+A GAV++LVP SVGAGHVVAKVRAVDADSGYNA
Sbjct: 546 GSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNA 605

Query: 605 WLSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATV 664
           WLSYELQ   G +RIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATV
Sbjct: 606 WLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATV 665

Query: 665 LVSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSA 724
           LVSLVESGQAPKASSR   GAA  EA LVDVNVYLIIAIC VSSLLVLT+LLYTAL  S 
Sbjct: 666 LVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSV 725

Query: 725 TPTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNKEEE 784
            PTEGA APGKPTLVCS AVGSWSYSQQRRQRVCS E PPKTDLMAFSPSL  G +  EE
Sbjct: 726 PPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAEE 785

Query: 785 GERQE 789
            +  E
Sbjct: 786 KQLSE 790


>gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo
           sapiens]
          Length = 844

 Score = 1187 bits (3072), Expect = 0.0
 Identities = 621/787 (78%), Positives = 669/787 (85%), Gaps = 2/787 (0%)

Query: 9   LGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRVAS 68
           LG   L L LLLL  WEVGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELVQRLFRVAS
Sbjct: 8   LGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVAS 67

Query: 69  KTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDIND 128
           K HGDLLEVNLQNGILFVNSRIDREELCG+S ECSIHLEVIVDRPLQVFHV+VEVKDIND
Sbjct: 68  KRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDIND 127

Query: 129 NPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNGKQ 188
           NPP FS+ EQKL I ES+  DSRFPLEGASDAD+ ENALLTY+LS NEYF LD      +
Sbjct: 128 NPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDK 187

Query: 189 IKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSEYK 248
            K   L+L+K LDRE+ P+L LLLTATDGGKPE TG+V LL+ VLD NDN P FD+  Y+
Sbjct: 188 DKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYE 247

Query: 249 VSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVNGTL 307
           V + EN   +TLV++LNA+D DEG+N E+ YS  S + P  R  F +++  GE++VN  +
Sbjct: 248 VKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAI 307

Query: 308 DYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPSTV 367
           D+E++  Y+I V  TDKG PPM GHCTV VE+LD NDNSPEV VTSLSLPV+EDAQ  TV
Sbjct: 308 DFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTV 367

Query: 368 IALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVTAR 427
           IALISVSD DSG NGQVTCSLTPHVPFKLVST+KNYYSLVLDSALDRE V AYELVVTAR
Sbjct: 368 IALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTAR 427

Query: 428 DGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 487
           DGGSP LWATA VSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQENA
Sbjct: 428 DGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENA 487

Query: 488 LVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLSSN 547
           LVSYSLVERRLG+R+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD GVPPL SN
Sbjct: 488 LVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSN 547

Query: 548 VTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNAWLS 607
           +TLQVFVLDENDNAPALLA+ AGSAGGAV++LV RSV AGHVVAKVRAVDADSGYNAWLS
Sbjct: 548 LTLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLS 607

Query: 608 YELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVS 667
           YELQ AA G+RIPFRVGLYTGEISTTRALDE DSPR RLLVLVKDHGEP+LTATATVLVS
Sbjct: 608 YELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVS 667

Query: 668 LVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSATPT 727
           LVE  QAPKASSR   G A PE ALVDVNVYLIIAIC VSSLLVLTLLLYTAL  SA PT
Sbjct: 668 LVEGSQAPKASSRASVGVA-PEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPT 726

Query: 728 EGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNKEEEGER 787
           EGAC P KPTLVCS AVGSWSYSQQRRQRVCS EG PK DLMAFSPSLP     + +GE 
Sbjct: 727 EGACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCPMVDVDGED 786

Query: 788 QEPGSNH 794
           Q  G +H
Sbjct: 787 QSIGGDH 793


>gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo
           sapiens]
          Length = 824

 Score = 1184 bits (3062), Expect = 0.0
 Identities = 615/785 (78%), Positives = 672/785 (85%), Gaps = 1/785 (0%)

Query: 6   RRGLGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFR 65
           R   G   L L LLLL   EVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV RLFR
Sbjct: 6   REDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFR 65

Query: 66  VASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKD 125
           VASK HGDLLEVNLQNGILFVNSRIDREELCG+SAECSIHLEVIVDRPLQVFHV VEVKD
Sbjct: 66  VASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKD 125

Query: 126 INDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTN 185
           INDN PVF +  + L I+ES+Q  SRF LEGASDADI  N+LLTY L   EYF+LD   N
Sbjct: 126 INDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRN 185

Query: 186 GKQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKS 245
            ++IK L L+LKK+L+RE TP+  LL+TA DGGKPELTGT +L + VLDVNDN P F+++
Sbjct: 186 DEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERT 245

Query: 246 EYKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVN 304
            YKV L+ENA   TLV+ +NATD DEGVN ++ YS  + +  +    F LD  NG++ V 
Sbjct: 246 IYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVK 305

Query: 305 GTLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQP 364
           G +D+EE+K Y+I+V+ATDKG PPM+ HCTV +EI+D NDN PE+ + SLSLPV ED+  
Sbjct: 306 GNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSPL 365

Query: 365 STVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVV 424
           STVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDS LDRE+V AYELVV
Sbjct: 366 STVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVV 425

Query: 425 TARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQ 484
           TARDGGSPSLWATA VSVEVADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSARDADAQ
Sbjct: 426 TARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADAQ 485

Query: 485 ENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL 544
           ENALVSYSLVERR+G+RALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL
Sbjct: 486 ENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL 545

Query: 545 SSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNA 604
            SNVTLQVFVLDENDNAPALL  + G  GGAV++LVPRSVGAGHVVAKVRAVDADSGYNA
Sbjct: 546 GSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYNA 605

Query: 605 WLSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATV 664
           WLSYELQP  GG+RIPFRVGLYTGEISTTRALDE D+PRHRLLVLVKDHGEP+LTATATV
Sbjct: 606 WLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLTATATV 665

Query: 665 LVSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSA 724
           LVSLVESGQAPKASS+  AGA  PEAALVDVNVYLI+AIC VSSLLVLTLLLYTAL  SA
Sbjct: 666 LVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTALRCSA 725

Query: 725 TPTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNKEEE 784
            PTEG C PGKPTLVCS AVGSWSYSQQR+QRVCS EG PKTDLMAFSPSLP      + 
Sbjct: 726 PPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCPISRDR 785

Query: 785 GERQE 789
            E+Q+
Sbjct: 786 EEKQD 790


>gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo
           sapiens]
          Length = 789

 Score = 1182 bits (3059), Expect = 0.0
 Identities = 607/770 (78%), Positives = 666/770 (86%), Gaps = 1/770 (0%)

Query: 10  GTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRVASK 69
           G   L L++++L  WE G GQLHYSV EEAKHG FVGRIAQDLGLELAELV RLFR   K
Sbjct: 10  GGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCK 69

Query: 70  THGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDINDN 129
             GDLLEVNLQNGILFVNSRIDREELCG+SAECSIHLEVIV+RPLQVFHV+VEVKDINDN
Sbjct: 70  FRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDN 129

Query: 130 PPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNGKQI 189
           PPVF   ++ L IAES+  DSRFPLEGASDADI ENALLTYRLS NEYF LD PT+ +Q+
Sbjct: 130 PPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQV 189

Query: 190 KRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSEYKV 249
           K L L+L+K LDRE+TPEL+LLLTATDGGKPELTGTV+LL+ VLD NDN P FD++ Y V
Sbjct: 190 KPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTV 249

Query: 250 SLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVNGTLD 308
            L EN +  TLV+  NA+D DEG+NG++ YS  S + P+ +  F +D  +G + V G +D
Sbjct: 250 KLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMD 309

Query: 309 YEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPSTVI 368
           +EE++ +KI V+A DKG PP+AGHCTV VE++D NDN+P++ +TSLSLP+ EDAQP TVI
Sbjct: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369

Query: 369 ALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVTARD 428
            LISV DRD GVNGQVTCSLTP VPFKLVSTFKNYYSLVLDSALDRE+V AYELVVTARD
Sbjct: 370 TLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429

Query: 429 GGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 488
           GGSPSLWATA VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL
Sbjct: 430 GGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNAL 489

Query: 489 VSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLSSNV 548
           VSYSLVE R+G+RALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL SNV
Sbjct: 490 VSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549

Query: 549 TLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNAWLSY 608
           TLQVFVLDENDNAPALLA + G  GGAV +LVPRSVGAGHVVAKVRAVDADSGYNAWLSY
Sbjct: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609

Query: 609 ELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSL 668
           ELQP A G+ IPFRVGLYTGEISTTRALDE D+PRHRLLVLVKDHGEP+LTATATVLVSL
Sbjct: 610 ELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSL 669

Query: 669 VESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSATPTE 728
           VESGQAPKASSR   G A PE  LVDVNVYLIIAIC VSSLLVLTLLLYTAL  SA  +E
Sbjct: 670 VESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSE 729

Query: 729 GACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLG 778
           GAC+  KPTLVCS AVGSWS+SQQRRQRVCS EGPPKTDLMAFSPSLP G
Sbjct: 730 GACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQG 779


>gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo
           sapiens]
          Length = 816

 Score = 1182 bits (3059), Expect = 0.0
 Identities = 609/777 (78%), Positives = 665/777 (85%), Gaps = 3/777 (0%)

Query: 4   FQRRG-LGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQR 62
           + RRG LG+  L LWLLL  +W+ GSGQLHYS+ EEAKHGTFVGRIAQDLGLELAELV R
Sbjct: 3   YSRRGSLGSRLLLLWLLLA-YWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPR 61

Query: 63  LFRVASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVE 122
           LFRVASK  GDLLEVNLQNGILFVNSRIDREELC + AECSIHLEVIVDRPLQVFHV V 
Sbjct: 62  LFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVA 121

Query: 123 VKDINDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDS 182
           VKDINDNPP FS +EQ+L I ES+  DSRFPLEGASD DI  NA L YRL+ NEYF LD 
Sbjct: 122 VKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDV 181

Query: 183 PTNGKQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEF 242
            TN ++   L L+L+KSLDRE+T E  LL+ ATDGGKPELTGTV+LL+ VLD NDN PEF
Sbjct: 182 KTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEF 241

Query: 243 DKSEYKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEV 301
           DKS Y V L+ENA   TLV+KLNA+D DEG+N E+ Y   + +  + +  F ++ N GE+
Sbjct: 242 DKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEI 301

Query: 302 RVNGTLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVRED 361
           +VNG LDYE+   Y+I + A DK T P++GHC V V++LD NDN+PE+A+T+L LPV+ED
Sbjct: 302 KVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKED 361

Query: 362 AQPSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYE 421
           A  STVIALISVSDRDSG NGQVTCSL PHVPFKLVSTFKNYYSLVLDSALDRE+V  YE
Sbjct: 362 APLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYE 421

Query: 422 LVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDA 481
           LVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSARDA
Sbjct: 422 LVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDA 481

Query: 482 DAQENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGV 541
           DAQENALVSYSLVERR+G+R LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGV
Sbjct: 482 DAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGV 541

Query: 542 PPLSSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSG 601
           PPL SNVTLQVFVLDENDNAPALL  + G  GGAV++LVPRSVGAGHVVAKVRAVD DSG
Sbjct: 542 PPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSG 601

Query: 602 YNAWLSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTAT 661
           YNAWLSYELQPA G +RIPFRVGLYTGEISTTR+LDE ++PRHRLLVLVKDHGEP LTAT
Sbjct: 602 YNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTAT 661

Query: 662 ATVLVSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALW 721
           ATVLVSLVESGQAPKASSR  AGA  PEAALVDVNVYLIIAIC VSSLLVLTLLLYTAL 
Sbjct: 662 ATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALR 721

Query: 722 WSATPTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLG 778
            SA PTE  C  GKPTL+CS AVGSWSYSQQRRQRVCS E PPKTDLMAFSPSLP G
Sbjct: 722 CSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQG 778


>gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens]
          Length = 842

 Score = 1157 bits (2994), Expect = 0.0
 Identities = 599/775 (77%), Positives = 661/775 (85%), Gaps = 2/775 (0%)

Query: 14  LQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRVASKTHGD 73
           L L LL+L  W VGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLF++ SK  GD
Sbjct: 14  LLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGRGD 73

Query: 74  LLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDINDNPPVF 133
           LLEVNLQNGILFVNSRIDREELCG+SAECSIHLEVIVDRPLQVFHV+VEVKDINDNPPVF
Sbjct: 74  LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPPVF 133

Query: 134 SLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNGKQIKRLS 193
              ++ L IAES+  DSRFPLEGASDADI ENALLTYRLS NEYF LD PT+ +Q+K L 
Sbjct: 134 PATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLG 193

Query: 194 LILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSEYKVSLME 253
           L+L+K LDRE+TPEL+LLLTATDGGKPELTGTV+LL+ VLD NDN P FD++ Y V L E
Sbjct: 194 LVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPE 253

Query: 254 NAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVNGTLDYEEN 312
           N +  TLV+  NA+D DEG+NG++ YS  S + P+ +  F +D  +G + V G +D+EE+
Sbjct: 254 NVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEES 313

Query: 313 KFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPSTVIALIS 372
           + +KI V+A DKG PP+AGHCT+ VE++D NDN+P++ + +LS+PV+EDAQ  TVIALIS
Sbjct: 314 RAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIALIS 373

Query: 373 VSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVTARDGGSP 432
           V D D+  NGQVTCSLTPHVPFKLVST+KNYYSLVLD ALDRE+V AYELVVTARDGGSP
Sbjct: 374 VIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGGSP 433

Query: 433 SLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYS 492
           SLWATARVSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSARDADAQENALVSYS
Sbjct: 434 SLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYS 493

Query: 493 LVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLSSNVTLQV 552
           LVERRLG+R+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL SNVTLQV
Sbjct: 494 LVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQV 553

Query: 553 FVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQP 612
           FVLDENDNAPALL  +     GAV+++V RSVGAG VV KVRAVDADSGYNAWLSYELQP
Sbjct: 554 FVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLSYELQP 613

Query: 613 AAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESG 672
               + IPFRVGLYTGEISTTRALDE D+PR RLLVLVKDHGEPALTATATVLVSLVESG
Sbjct: 614 ETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVSLVESG 673

Query: 673 QAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSATPTEGACA 732
           QAPK+SSR   GA  PE  LVDVNVYLIIAIC VSSLLVLTLLLYT L  SA PTEG CA
Sbjct: 674 QAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMPTEGECA 733

Query: 733 PGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSL-PLGLNKEEEGE 786
           PGKPTLVCS AVGSWSYSQQRRQRVCS EG  KTDLMAFSP L P   + E  GE
Sbjct: 734 PGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCAGSTERTGE 788


>gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo
           sapiens]
          Length = 685

 Score =  790 bits (2040), Expect = 0.0
 Identities = 406/526 (77%), Positives = 445/526 (84%), Gaps = 1/526 (0%)

Query: 9   LGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRVAS 68
           LG   L L LLLL  WEVGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELVQRLFRVAS
Sbjct: 8   LGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVAS 67

Query: 69  KTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDIND 128
           K HGDLLEVNLQNGILFVNSRIDREELCG+S ECSIHLEVIVDRPLQVFHV+VEVKDIND
Sbjct: 68  KRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDIND 127

Query: 129 NPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNGKQ 188
           NPP FS+ EQKL I ES+  DSRFPLEGASDAD+ ENALLTY+LS NEYF LD      +
Sbjct: 128 NPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDK 187

Query: 189 IKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSEYK 248
            K   L+L+K LDRE+ P+L LLLTATDGGKPE TG+V LL+ VLD NDN P FD+  Y+
Sbjct: 188 DKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYE 247

Query: 249 VSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVNGTL 307
           V + EN   +TLV++LNA+D DEG+N E+ YS  S + P  R  F +++  GE++VN  +
Sbjct: 248 VKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAI 307

Query: 308 DYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPSTV 367
           D+E++  Y+I V  TDKG PPM GHCTV VE+LD NDNSPEV VTSLSLPV+EDAQ  TV
Sbjct: 308 DFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTV 367

Query: 368 IALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVTAR 427
           IALISVSD DSG NGQVTCSLTPHVPFKLVST+KNYYSLVLDSALDRE V AYELVVTAR
Sbjct: 368 IALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTAR 427

Query: 428 DGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 487
           DGGSP LWATA VSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQENA
Sbjct: 428 DGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENA 487

Query: 488 LVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQ 533
           LVSYSLVERRLG+R+LSSYVSVHAESGKVYALQPLDHEELELLQFQ
Sbjct: 488 LVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQ 533



 Score =  436 bits (1122), Expect = e-122
 Identities = 295/669 (44%), Positives = 360/669 (53%), Gaps = 66/669 (9%)

Query: 291 LFTLDQNNGEVRVNGTLDYEENKFYKIEVQATDK---GTPPMAGHCTVWVEILDTNDNSP 347
           L  ++  NG + VN  +D EE     +E     +     P    H  V VE+ D NDN P
Sbjct: 73  LLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFH--VDVEVKDINDNPP 130

Query: 348 EVAVTSLSLPVREDAQPSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKN----Y 403
             +VT   L + E     +   L   SD D G N  +T  L+P+  F L    K     +
Sbjct: 131 RFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKDKF 190

Query: 404 YSLVLDSALDRENVWAYELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFV 463
             LVL   LDRE     +L++TA DGG P    +  + + V D NDNAP F +P Y V +
Sbjct: 191 PVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEVKM 250

Query: 464 KENNPPGCHIFTVSARDADAQENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLD 523
            EN      +  ++A D+D   N  + YS     L    +     ++  +G++     +D
Sbjct: 251 YENQVNQTLVIRLNASDSDEGINKEMMYSFSS--LVPPTIRRKFWINERTGEIKVNDAID 308

Query: 524 HEELELLQFQVSARDAGVPPLSSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRS 583
            E+    +  V   D G PP+  + T+ V +LDENDN+P ++ T       +++  V   
Sbjct: 309 FEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVT-------SLSLPVKED 361

Query: 584 VGAGHVVAKVRAVDADSGYNAWLSYELQPAAGGSRIPFR-VGLYTGEISTT--RALDEAD 640
              G V+A +   D DSG N  ++  L P      +PF+ V  Y    S     ALD   
Sbjct: 362 AQVGTVIALISVSDHDSGANGQVTCSLTP-----HVPFKLVSTYKNYYSLVLDSALDRER 416

Query: 641 SPRHRLLVLVKDHGEPALTATATVLVSLVESGQAPKASSRTLAGAASPEAALVDVNVYLI 700
              + L+V  +D G P L ATA+V V + +       +    A A S     V  N    
Sbjct: 417 VSAYELVVTARDGGSPPLWATASVSVEVAD------VNDNAPAFAQSEYTVFVKENNPPG 470

Query: 701 IAICVVSSLLVLTLLLYTALWWSATPTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSE 760
             I  VS+             W A   E A        +  R +G  S S      V +E
Sbjct: 471 CHIFTVSA-------------WDADAQENALVSYS---LVERRLGERSLSSY--VSVHAE 512

Query: 761 EGPPKTDLMAFSPSLPLGLNKEEEGERQEPGSNHPGQPRQPNPDWRYSASLRAGMHSSVH 820
            G     + A  P     L+ EE    Q        QPRQPNPDWRYSASLRAGMHSSVH
Sbjct: 513 SGK----VYALQP-----LDHEELELLQF-------QPRQPNPDWRYSASLRAGMHSSVH 556

Query: 821 LEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGP 880
           LEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGP
Sbjct: 557 LEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGP 616

Query: 881 GELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKG 940
           GELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKG
Sbjct: 617 GELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKG 676

Query: 941 NSTTDNSDQ 949
           NSTTDNSDQ
Sbjct: 677 NSTTDNSDQ 685



 Score =  152 bits (383), Expect = 2e-36
 Identities = 121/399 (30%), Positives = 188/399 (47%), Gaps = 27/399 (6%)

Query: 230 VQVLDVNDNDPEFDKSEYKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMSIKPNGR 289
           V+V D+NDN P F  +E K+S+ E+   ++      A+D D G N  +TY L    PN  
Sbjct: 120 VEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKL---SPN-- 174

Query: 290 HLFTLDQNNGEVR-------VNGTLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDT 342
             F LD  N + +       +   LD EEN   K+ + ATD G P   G  ++ + +LD 
Sbjct: 175 EYFVLDIINKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDA 234

Query: 343 NDNSPEVAVTSLSLPVREDAQPSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTF-- 400
           NDN+P        + + E+    T++  ++ SD D G+N ++  S +  VP  +   F  
Sbjct: 235 NDNAPIFDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWI 294

Query: 401 -KNYYSLVLDSALDRENVWAYELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEY 459
            +    + ++ A+D E+   YE+ V   D G+P +     V VE+ D NDN+P       
Sbjct: 295 NERTGEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSL 354

Query: 460 TVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRLGDRALSSYVSVHAESGKVYAL 519
           ++ VKE+   G  I  +S  D D+  N  V+ SL    +  + +S+Y + ++    +   
Sbjct: 355 SLPVKEDAQVGTVIALISVSDHDSGANGQVTCSLTPH-VPFKLVSTYKNYYS----LVLD 409

Query: 520 QPLDHEELELLQFQVSARDAGVPPLSSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKL 579
             LD E +   +  V+ARD G PPL +  ++ V V D NDNAPA        A       
Sbjct: 410 SALDRERVSAYELVVTARDGGSPPLWATASVSVEVADVNDNAPAF-------AQSEYTVF 462

Query: 580 VPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPAAGGSR 618
           V  +   G  +  V A DAD+  NA +SY L     G R
Sbjct: 463 VKENNPPGCHIFTVSAWDADAQENALVSYSLVERRLGER 501


>gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo
           sapiens]
          Length = 686

 Score =  790 bits (2039), Expect = 0.0
 Identities = 403/526 (76%), Positives = 450/526 (85%), Gaps = 1/526 (0%)

Query: 9   LGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRVAS 68
           LG   L L LLLL  W+VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV RLFR+AS
Sbjct: 9   LGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMAS 68

Query: 69  KTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDIND 128
           K   DLLEVNLQNGILFVNSRIDREELCG+SAECSIHLEVIVDRPLQVFHV+VEV+DIND
Sbjct: 69  KDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDIND 128

Query: 129 NPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNGKQ 188
           NPP+F + EQ++LI ES+  DS FPLEGASDAD+  N++LTY+LS +EYF LD   N   
Sbjct: 129 NPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDD 188

Query: 189 IKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSEYK 248
            K++ L+LKKSLDRE+ P  NL LTATDGGKPELTGTV+LLV VLDVNDN P F++SEY+
Sbjct: 189 NKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248

Query: 249 VSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVNGTL 307
           V + ENA   T V++LNA+DRDEG NG ++YS  S +       F++D+N GE+ + G L
Sbjct: 249 VRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNL 308

Query: 308 DYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPSTV 367
           D+E+   YKI + ATDKG PPMAGHCTV V ILD NDN PE+A+TSLSLPVREDAQ  TV
Sbjct: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368

Query: 368 IALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVTAR 427
           IALISV+D DSG NGQV CSLTPHVPFKLVSTFKNYYSLVLDSALDRE+V AYELVVTAR
Sbjct: 369 IALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTAR 428

Query: 428 DGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 487
           DGGSPSLWATA +SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA
Sbjct: 429 DGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488

Query: 488 LVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQ 533
           LVSYSLVERR+G+RALSSY+SVHAESGKVYALQPLDHEELELLQFQ
Sbjct: 489 LVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQ 534



 Score =  320 bits (821), Expect = 3e-87
 Identities = 153/153 (100%), Positives = 153/153 (100%)

Query: 797 QPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPP 856
           QPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPP
Sbjct: 534 QPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPP 593

Query: 857 VGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFG 916
           VGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFG
Sbjct: 594 VGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFG 653

Query: 917 KKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 949
           KKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 654 KKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 686



 Score =  157 bits (398), Expect = 3e-38
 Identities = 117/394 (29%), Positives = 186/394 (47%), Gaps = 17/394 (4%)

Query: 230 VQVLDVNDNDPEFDKSEYKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMSIKPNGR 289
           V+V D+NDN P F   E +V + E+   +++     A+D D G N  +TY L S +  G 
Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180

Query: 290 HLFTLDQNNGEVRV--NGTLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSP 347
            +     +N ++ +    +LD EE   + + + ATD G P + G   + V +LD NDN+P
Sbjct: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240

Query: 348 EVAVTSLSLPVREDAQPSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTF---KNYY 404
               +   + + E+A   T +  ++ SDRD G NG ++ S    V   ++  F   +N  
Sbjct: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300

Query: 405 SLVLDSALDRENVWAYELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVK 464
            +V+   LD E    Y++++ A D G P +     V V + D NDN P  A    ++ V+
Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360

Query: 465 ENNPPGCHIFTVSARDADAQENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDH 524
           E+   G  I  +S  D D+  N  V+ SL    +  + +S++ + ++    +     LD 
Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPH-VPFKLVSTFKNYYS----LVLDSALDR 415

Query: 525 EELELLQFQVSARDAGVPPLSSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSV 584
           E +   +  V+ARD G P L +  +L V V D NDNAPA        A       V  + 
Sbjct: 416 ESVSAYELVVTARDGGSPSLWATASLSVEVADMNDNAPAF-------AQPEYTVFVKENN 468

Query: 585 GAGHVVAKVRAVDADSGYNAWLSYELQPAAGGSR 618
             G  +  V A DAD+  NA +SY L     G R
Sbjct: 469 PPGCHIFTVSARDADAQENALVSYSLVERRVGER 502


>gi|14165402 protocadherin alpha 1 isoform 3 precursor [Homo
           sapiens]
          Length = 686

 Score =  788 bits (2036), Expect = 0.0
 Identities = 406/530 (76%), Positives = 453/530 (85%), Gaps = 1/530 (0%)

Query: 5   QRRGLGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLF 64
           +R GLG   L LWLLLL  WEVGSGQLHYS+ EEAKHGTFVGR+AQDLGLELAELV RLF
Sbjct: 5   RRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELVPRLF 64

Query: 65  RVASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVK 124
           RVASKTH DLLEVNLQNGILFVNSRIDREELC  SAECSIHLE+I DRPLQVFHV V+VK
Sbjct: 65  RVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVEVKVK 124

Query: 125 DINDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPT 184
           DINDNPPVF  REQ + I ES+  +SRFP+EGA+DADI  NALLTY LS ++YFSLD   
Sbjct: 125 DINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSLDVEA 184

Query: 185 NGKQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDK 244
           + +  K L L L+K LDRE+TPEL+LLLTATDGGKPEL GTV LL+ VLDVNDN P FD+
Sbjct: 185 SDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAPLFDQ 244

Query: 245 SEYKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRV 303
           + Y+V L+E  A  TLV  LNA+D DEGVNGEV +S  S I  + +  F +D ++GE+R+
Sbjct: 245 AVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSGEIRL 304

Query: 304 NGTLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQ 363
              LDYEE K Y+I+V+A DKG+PPM+ HC V V++LD NDN+PE+AVTSL LP+REDA 
Sbjct: 305 IDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIREDAP 364

Query: 364 PSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELV 423
            STVIALI+VSDRDSG NGQVTCSL PHVPFKLVSTFKNYYSLVLDSALDRE++  YELV
Sbjct: 365 LSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSVYELV 424

Query: 424 VTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADA 483
           VTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADA
Sbjct: 425 VTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADA 484

Query: 484 QENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQ 533
           QENALVSYSLVERR+G+RALS+YVSVHAESGKVYALQPLDHEELELLQFQ
Sbjct: 485 QENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQ 534



 Score =  320 bits (821), Expect = 3e-87
 Identities = 153/153 (100%), Positives = 153/153 (100%)

Query: 797 QPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPP 856
           QPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPP
Sbjct: 534 QPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPP 593

Query: 857 VGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFG 916
           VGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFG
Sbjct: 594 VGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFG 653

Query: 917 KKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 949
           KKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 654 KKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 686



 Score =  144 bits (362), Expect = 5e-34
 Identities = 119/399 (29%), Positives = 181/399 (45%), Gaps = 27/399 (6%)

Query: 230 VQVLDVNDNDPEFDKSEYKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMSIKPNGR 289
           V+V D+NDN P F   E  + + E+    +      A D D G N  +TY+L     +  
Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTL-----SPS 175

Query: 290 HLFTLDQNNGE-------VRVNGTLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDT 342
             F+LD    +       + +   LD EE     + + ATD G P + G   + + +LD 
Sbjct: 176 DYFSLDVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDV 235

Query: 343 NDNSPEVAVTSLSLPVREDAQPSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKN 402
           NDN+P        + + E     T++  ++ SD D GVNG+V  S    +   +   FK 
Sbjct: 236 NDNAPLFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKV 295

Query: 403 YYS---LVLDSALDRENVWAYELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEY 459
             S   + L   LD E   +YE+ V A D GSP +    +V V+V DVNDNAP  A    
Sbjct: 296 DSSSGEIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSL 355

Query: 460 TVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRLGDRALSSYVSVHAESGKVYAL 519
            + ++E+ P    I  ++  D D+  N  V+ SL+   +  + +S++ + ++    +   
Sbjct: 356 YLPIREDAPLSTVIALITVSDRDSGANGQVTCSLMPH-VPFKLVSTFKNYYS----LVLD 410

Query: 520 QPLDHEELELLQFQVSARDAGVPPLSSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKL 579
             LD E L + +  V+ARD G P L +   + V V D NDNAPA        A       
Sbjct: 411 SALDRESLSVYELVVTARDGGSPSLWATARVSVEVADVNDNAPAF-------AQPEYTVF 463

Query: 580 VPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPAAGGSR 618
           V  +   G  +  V A DAD+  NA +SY L     G R
Sbjct: 464 VKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGER 502


>gi|14277675 protocadherin gamma subfamily C, 3 isoform 1 precursor
           [Homo sapiens]
          Length = 934

 Score =  605 bits (1559), Expect = e-173
 Identities = 367/950 (38%), Positives = 540/950 (56%), Gaps = 50/950 (5%)

Query: 6   RRGL-GTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLF 64
           R GL  T R+   LLLL      S  +HY + EE + G  VG +  +LGL+L  L  R F
Sbjct: 7   RSGLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRF 66

Query: 65  RVASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVK 124
           RV S       EVN + G +FVN R+DREELCG    C++ LE++V+ PL++F V V ++
Sbjct: 67  RVVSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQ 126

Query: 125 DINDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPT 184
           DINDN P F  +E KL I+E+    +RFPLE A D D+  N+L TY LS+NEYF+L   T
Sbjct: 127 DINDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQT 186

Query: 185 NGKQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDK 244
                K   L+L+++LDRE+ P L L+LTA DGG P L+ ++ + ++VLD NDN P F++
Sbjct: 187 REDSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQ 246

Query: 245 SEYKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMSIKPNG-RHLFTLDQNNGEVRV 303
           S Y+  ++E+A   T V+++ ATD DEG NGE+ YS  S    G R LF LD   G + +
Sbjct: 247 SLYRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTI 306

Query: 304 NGTLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQ 363
            G LD+E+ K ++I +QA DKG  P   HC V VE++D NDN+PE+ VTS+  PV EDA 
Sbjct: 307 KGRLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAP 366

Query: 364 PSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELV 423
             TVIAL+SV+D D+G NG VTC + P +PF L S+ KNY++L   + LDRE V  Y L 
Sbjct: 367 LGTVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLS 426

Query: 424 VTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADA 483
           +TARD G+PSL A   V V+V+D+NDN P  +Q  Y V+++ENN PG  I  +S  D DA
Sbjct: 427 ITARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDA 486

Query: 484 QENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPP 543
            +NA +S+ L+E+      +  Y +++ ++G V +L PLD+E+    +      D G P 
Sbjct: 487 PQNARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPV 546

Query: 544 LSSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYN 603
           L++N+++ +FV D NDNAP +L  +    GG+  +++PR   AGH+V++V   DAD+G+N
Sbjct: 547 LATNISVNIFVTDRNDNAPQVLYPR---PGGSSVEMLPRGTSAGHLVSRVVGWDADAGHN 603

Query: 604 AWLSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATAT 663
           AWLSY L  +   S   F +GL+TG+IST R + + DSPR  L VL+KD+GEP+L+ TAT
Sbjct: 604 AWLSYSLLGSPNQSL--FAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTAT 661

Query: 664 VLVSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLT---LLLYTAL 720
           + VS+ E   +P+A +   +G+A P     ++  YL++++ +VS   V+T   ++++   
Sbjct: 662 LTVSVTE--DSPEARAEFPSGSA-PREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVY 718

Query: 721 WWSAT------PTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPS 774
            W  +      P         P+L    AV     S     +V       ++D +   P 
Sbjct: 719 KWKQSRDLYRAPVSSLYRTPGPSLHAD-AVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPG 777

Query: 775 LPLGLNKEEEGERQ-EP---------GSNHPGQPRQPNPDWRYSASLRAGMHSSVHLEEA 824
               L   +   R  +P          S  PGQ   PN DWR+S + R G   S + ++ 
Sbjct: 778 AASPLASRQNTLRSCDPVFYRQVLGAESAPPGQQAPPNTDWRFSQAQRPGTSGSQNGDDT 837

Query: 825 GILRAGPGGPDQQWPT-------VSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQ 877
           G        P+ Q+ T       ++SA+   EA + S  +G G  +   + +YGP    Q
Sbjct: 838 GT------WPNNQFDTEMLQAMILASAS---EAADGSSTLGGGAGTMGLSARYGPQFTLQ 888

Query: 878 SGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKK 927
             P +      IPGS A ++        +  K+     G K+++ KK+KK
Sbjct: 889 HVP-DYRQNVYIPGSNATLT---NAAGKRDGKAPAGGNGNKKKSGKKEKK 934


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.131    0.378 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,525,901
Number of Sequences: 37866
Number of extensions: 2020803
Number of successful extensions: 15265
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 217
Number of HSP's successfully gapped in prelim test: 112
Number of HSP's that attempted gapping in prelim test: 7549
Number of HSP's gapped (non-prelim): 1277
length of query: 949
length of database: 18,247,518
effective HSP length: 112
effective length of query: 837
effective length of database: 14,006,526
effective search space: 11723462262
effective search space used: 11723462262
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.