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Search of human proteins with 90193626
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|90193626 cadherin 9, type 2 preproprotein [Homo sapiens]
(789 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|90193626 cadherin 9, type 2 preproprotein [Homo sapiens] 1596 0.0
gi|4826673 cadherin 6, type 2 preproprotein [Homo sapiens] 1173 0.0
gi|16306530 cadherin 10, type 2 preproprotein [Homo sapiens] 1145 0.0
gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens] 948 0.0
gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens] 934 0.0
gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens] 934 0.0
gi|4826671 cadherin 18, type 2 preproprotein [Homo sapiens] 921 0.0
gi|16306532 cadherin 11, type 2 preproprotein [Homo sapiens] 904 0.0
gi|16306539 cadherin 8, type 2 preproprotein [Homo sapiens] 896 0.0
gi|16306537 cadherin 20, type 2 preproprotein [Homo sapiens] 889 0.0
gi|16753221 cadherin 22 precursor [Homo sapiens] 802 0.0
gi|32880203 cadherin-like 24 isoform 2 [Homo sapiens] 744 0.0
gi|32880206 cadherin-like 24 isoform 1 [Homo sapiens] 726 0.0
gi|12656655 cadherin 19, type 2 preproprotein [Homo sapiens] 716 0.0
gi|166362713 cadherin 5, type 2 preproprotein [Homo sapiens] 531 e-151
gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens] 423 e-118
gi|14589893 cadherin 4, type 1 preproprotein [Homo sapiens] 421 e-117
gi|4757960 cadherin 1, type 1 preproprotein [Homo sapiens] 371 e-102
gi|14589891 cadherin 3, type 1 preproprotein [Homo sapiens] 360 2e-99
gi|4826669 cadherin 15 preproprotein [Homo sapiens] 344 2e-94
gi|148539848 desmocollin 3 isoform Dsc3b preproprotein [Homo sap... 229 6e-60
gi|148539846 desmocollin 3 isoform Dsc3a preproprotein [Homo sap... 229 6e-60
gi|4826702 desmocollin 1 isoform Dsc1b preproprotein [Homo sapiens] 227 4e-59
gi|13435361 desmocollin 1 isoform Dsc1a preproprotein [Homo sapi... 227 4e-59
gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo sapi... 214 2e-55
gi|13435364 desmocollin 2 isoform Dsc2a preproprotein [Homo sapi... 214 2e-55
gi|4502719 cadherin 13 preproprotein [Homo sapiens] 214 3e-55
gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens] 213 6e-55
gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens] 196 9e-50
gi|29570800 cadherin-like 26 isoform a [Homo sapiens] 194 3e-49
>gi|90193626 cadherin 9, type 2 preproprotein [Homo sapiens]
Length = 789
Score = 1596 bits (4133), Expect = 0.0
Identities = 789/789 (100%), Positives = 789/789 (100%)
Query: 1 MRTYHYIPLFIWTYMFHTVDTILLQEKPNSYLSSKKIAGLTKDDGKMLRRTKRGWMWNQF 60
MRTYHYIPLFIWTYMFHTVDTILLQEKPNSYLSSKKIAGLTKDDGKMLRRTKRGWMWNQF
Sbjct: 1 MRTYHYIPLFIWTYMFHTVDTILLQEKPNSYLSSKKIAGLTKDDGKMLRRTKRGWMWNQF 60
Query: 61 FLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILTGDGAGSLFVIDENTGDIHAAKKLDREE 120
FLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILTGDGAGSLFVIDENTGDIHAAKKLDREE
Sbjct: 61 FLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILTGDGAGSLFVIDENTGDIHAAKKLDREE 120
Query: 121 KSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTKDLYTASVPEMSGVGTSVIQ 180
KSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTKDLYTASVPEMSGVGTSVIQ
Sbjct: 121 KSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTKDLYTASVPEMSGVGTSVIQ 180
Query: 181 VTATDADDANYGNSAKVVYSILQGQPYFSVDPESGIIKTALPDMSRENREQYQVVIQAKD 240
VTATDADDANYGNSAKVVYSILQGQPYFSVDPESGIIKTALPDMSRENREQYQVVIQAKD
Sbjct: 181 VTATDADDANYGNSAKVVYSILQGQPYFSVDPESGIIKTALPDMSRENREQYQVVIQAKD 240
Query: 241 MGGQMGGLSGTTTVNITLTDVNNNPPRFPQSTYQFNSPESVPLGTHLGRIKANDPDVGEN 300
MGGQMGGLSGTTTVNITLTDVNNNPPRFPQSTYQFNSPESVPLGTHLGRIKANDPDVGEN
Sbjct: 241 MGGQMGGLSGTTTVNITLTDVNNNPPRFPQSTYQFNSPESVPLGTHLGRIKANDPDVGEN 300
Query: 301 AEMEYSIAEGDGADMFDVITDKDTQEGIITVKQNLDFENQMLYTLRVDASNTHPDPRFLH 360
AEMEYSIAEGDGADMFDVITDKDTQEGIITVKQNLDFENQMLYTLRVDASNTHPDPRFLH
Sbjct: 301 AEMEYSIAEGDGADMFDVITDKDTQEGIITVKQNLDFENQMLYTLRVDASNTHPDPRFLH 360
Query: 361 LGPFKDTAVVKISVEDIDEPPVFTKVSYLIEVDEDVKEGSIIGQVTAYDPDARNNLIKYS 420
LGPFKDTAVVKISVEDIDEPPVFTKVSYLIEVDEDVKEGSIIGQVTAYDPDARNNLIKYS
Sbjct: 361 LGPFKDTAVVKISVEDIDEPPVFTKVSYLIEVDEDVKEGSIIGQVTAYDPDARNNLIKYS 420
Query: 421 VDRHTDMDRIFGIHSENGSIFTLKALDRESSPWHNITVTATEINNPKQSSHIPVFIRILD 480
VDRHTDMDRIFGIHSENGSIFTLKALDRESSPWHNITVTATEINNPKQSSHIPVFIRILD
Sbjct: 421 VDRHTDMDRIFGIHSENGSIFTLKALDRESSPWHNITVTATEINNPKQSSHIPVFIRILD 480
Query: 481 INDHAPEFAMYYETFVCENAKPGQLIQTVSVMDKDDPPRGHKFFFEPVPEFTLNPNFTIV 540
INDHAPEFAMYYETFVCENAKPGQLIQTVSVMDKDDPPRGHKFFFEPVPEFTLNPNFTIV
Sbjct: 481 INDHAPEFAMYYETFVCENAKPGQLIQTVSVMDKDDPPRGHKFFFEPVPEFTLNPNFTIV 540
Query: 541 DNKDNTAGIMTRKDGYSRNKMSTYLLPILIFDNDYPIQSSTGTLTIRVCACDNQGNMQSC 600
DNKDNTAGIMTRKDGYSRNKMSTYLLPILIFDNDYPIQSSTGTLTIRVCACDNQGNMQSC
Sbjct: 541 DNKDNTAGIMTRKDGYSRNKMSTYLLPILIFDNDYPIQSSTGTLTIRVCACDNQGNMQSC 600
Query: 601 TAEALILSAGLSTGALVAILLCVLILLILVVLFAALKRQRKKEPLIISKDDVRDNIVTYN 660
TAEALILSAGLSTGALVAILLCVLILLILVVLFAALKRQRKKEPLIISKDDVRDNIVTYN
Sbjct: 601 TAEALILSAGLSTGALVAILLCVLILLILVVLFAALKRQRKKEPLIISKDDVRDNIVTYN 660
Query: 661 DEGGGEEDTQAFDIGTLRNPEAREDSKLRRDVMPETIFQIRRTVPLWENIDVQDFIHRRL 720
DEGGGEEDTQAFDIGTLRNPEAREDSKLRRDVMPETIFQIRRTVPLWENIDVQDFIHRRL
Sbjct: 661 DEGGGEEDTQAFDIGTLRNPEAREDSKLRRDVMPETIFQIRRTVPLWENIDVQDFIHRRL 720
Query: 721 KENDADPSAPPYDSLATYAYEGNDSIADSLSSLESLTADCNQDYDYLSDWGPRFKKLADM 780
KENDADPSAPPYDSLATYAYEGNDSIADSLSSLESLTADCNQDYDYLSDWGPRFKKLADM
Sbjct: 721 KENDADPSAPPYDSLATYAYEGNDSIADSLSSLESLTADCNQDYDYLSDWGPRFKKLADM 780
Query: 781 YGGDDSDRD 789
YGGDDSDRD
Sbjct: 781 YGGDDSDRD 789
>gi|4826673 cadherin 6, type 2 preproprotein [Homo sapiens]
Length = 790
Score = 1173 bits (3034), Expect = 0.0
Identities = 570/789 (72%), Positives = 673/789 (85%)
Query: 1 MRTYHYIPLFIWTYMFHTVDTILLQEKPNSYLSSKKIAGLTKDDGKMLRRTKRGWMWNQF 60
MRTY Y L W + + L ++ + + + K+ L+ + L R+KR WMWNQF
Sbjct: 1 MRTYRYFLLLFWVGQPYPTLSTPLSKRTSGFPAKKRALELSGNSKNELNRSKRSWMWNQF 60
Query: 61 FLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILTGDGAGSLFVIDENTGDIHAAKKLDREE 120
FLLEEYTG+D QYVGKLH+DQD+GDG+LKYIL+GDGAG LF+I+ENTGDI A K+LDREE
Sbjct: 61 FLLEEYTGSDYQYVGKLHSDQDRGDGSLKYILSGDGAGDLFIINENTGDIQATKRLDREE 120
Query: 121 KSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTKDLYTASVPEMSGVGTSVIQ 180
K +YILRA+AI+R+TGR VEPESEFIIKIHDINDNEP FTK++YTA+VPEMS VGT V+Q
Sbjct: 121 KPVYILRAQAINRRTGRPVEPESEFIIKIHDINDNEPIFTKEVYTATVPEMSDVGTFVVQ 180
Query: 181 VTATDADDANYGNSAKVVYSILQGQPYFSVDPESGIIKTALPDMSRENREQYQVVIQAKD 240
VTATDADD YGNSAKVVYSILQGQPYFSV+ E+GIIKTAL +M RENREQYQVVIQAKD
Sbjct: 181 VTATDADDPTYGNSAKVVYSILQGQPYFSVESETGIIKTALLNMDRENREQYQVVIQAKD 240
Query: 241 MGGQMGGLSGTTTVNITLTDVNNNPPRFPQSTYQFNSPESVPLGTHLGRIKANDPDVGEN 300
MGGQMGGLSGTTTVNITLTDVN+NPPRFPQSTYQF +PES P GT +GRIKA+D DVGEN
Sbjct: 241 MGGQMGGLSGTTTVNITLTDVNDNPPRFPQSTYQFKTPESSPPGTPIGRIKASDADVGEN 300
Query: 301 AEMEYSIAEGDGADMFDVITDKDTQEGIITVKQNLDFENQMLYTLRVDASNTHPDPRFLH 360
AE+EYSI +G+G DMFDVITD++TQEGIITVK+ LDFE + +YTL+V+ASN + +PRFL+
Sbjct: 301 AEIEYSITDGEGLDMFDVITDQETQEGIITVKKLLDFEKKKVYTLKVEASNPYVEPRFLY 360
Query: 361 LGPFKDTAVVKISVEDIDEPPVFTKVSYLIEVDEDVKEGSIIGQVTAYDPDARNNLIKYS 420
LGPFKD+A V+I VED+DEPPVF+K++Y++++ ED + + IG VTA DPDA N +KYS
Sbjct: 361 LGPFKDSATVRIVVEDVDEPPVFSKLAYILQIREDAQINTTIGSVTAQDPDAARNPVKYS 420
Query: 421 VDRHTDMDRIFGIHSENGSIFTLKALDRESSPWHNITVTATEINNPKQSSHIPVFIRILD 480
VDRHTDMDRIF I S NGSIFT K LDRE+ WHNITV ATEINNPKQSS +P++I++LD
Sbjct: 421 VDRHTDMDRIFNIDSGNGSIFTSKLLDRETLLWHNITVIATEINNPKQSSRVPLYIKVLD 480
Query: 481 INDHAPEFAMYYETFVCENAKPGQLIQTVSVMDKDDPPRGHKFFFEPVPEFTLNPNFTIV 540
+ND+APEFA +YETFVCE AK QLIQT+ +DKDDP GH+F F PE NFTI
Sbjct: 481 VNDNAPEFAEFYETFVCEKAKADQLIQTLHAVDKDDPYSGHQFSFSLAPEAASGSNFTIQ 540
Query: 541 DNKDNTAGIMTRKDGYSRNKMSTYLLPILIFDNDYPIQSSTGTLTIRVCACDNQGNMQSC 600
DNKDNTAGI+TRK+GY+R++MSTYLLP++I DNDYP+QSSTGT+T+RVCACD+ GNMQSC
Sbjct: 541 DNKDNTAGILTRKNGYNRHEMSTYLLPVVISDNDYPVQSSTGTVTVRVCACDHHGNMQSC 600
Query: 601 TAEALILSAGLSTGALVAILLCVLILLILVVLFAALKRQRKKEPLIISKDDVRDNIVTYN 660
AEALI GLSTGALVAILLC++ILL+ VVLFAAL+RQRKKEPLIISK+D+RDNIV+YN
Sbjct: 601 HAEALIHPTGLSTGALVAILLCIVILLVTVVLFAALRRQRKKEPLIISKEDIRDNIVSYN 660
Query: 661 DEGGGEEDTQAFDIGTLRNPEAREDSKLRRDVMPETIFQIRRTVPLWENIDVQDFIHRRL 720
DEGGGEEDTQAFDIGTLRNPEA ED+KLRRD++PE +F RRT +N DV+DFI++RL
Sbjct: 661 DEGGGEEDTQAFDIGTLRNPEAIEDNKLRRDIVPEALFLPRRTPTARDNTDVRDFINQRL 720
Query: 721 KENDADPSAPPYDSLATYAYEGNDSIADSLSSLESLTADCNQDYDYLSDWGPRFKKLADM 780
KEND DP+APPYDSLATYAYEG S+ADSLSSLES+T D +QDYDYLSDWGPRFKKLADM
Sbjct: 721 KENDTDPTAPPYDSLATYAYEGTGSVADSLSSLESVTTDADQDYDYLSDWGPRFKKLADM 780
Query: 781 YGGDDSDRD 789
YGG DSD+D
Sbjct: 781 YGGVDSDKD 789
>gi|16306530 cadherin 10, type 2 preproprotein [Homo sapiens]
Length = 788
Score = 1145 bits (2963), Expect = 0.0
Identities = 549/793 (69%), Positives = 679/793 (85%), Gaps = 10/793 (1%)
Query: 1 MRTYHYIPLFI-WTYMFHTVDTILLQEK---PNSYLSSKKIAGLTKDDGKMLRRTKRGWM 56
M + ++ LF+ W + H ++ + P + S ++ + DGK+L R KRGWM
Sbjct: 1 MTIHQFLLLFLFWVCLPHFCSPEIMFRRTPVPQQRILSSRVP---RSDGKILHRQKRGWM 57
Query: 57 WNQFFLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILTGDGAGSLFVIDENTGDIHAAKKL 116
WNQFFLLEEYTG+D QYVGKLH+DQDKGDG+LKYIL+GDGAG+LF+IDE TGDIHA +++
Sbjct: 58 WNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSGDGAGTLFIIDEKTGDIHATRRI 117
Query: 117 DREEKSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTKDLYTASVPEMSGVGT 176
DREEK+ Y LRA+AI+R+T R VEPESEF+IKIHDINDNEP F +++YTASVPEMS VGT
Sbjct: 118 DREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFPEEIYTASVPEMSVVGT 177
Query: 177 SVIQVTATDADDANYGNSAKVVYSILQGQPYFSVDPESGIIKTALPDMSRENREQYQVVI 236
SV+QVTATDADD +YGNSA+V+YSILQGQPYFSV+PE+GII+TALP+M+RENREQYQVVI
Sbjct: 178 SVVQVTATDADDPSYGNSARVIYSILQGQPYFSVEPETGIIRTALPNMNRENREQYQVVI 237
Query: 237 QAKDMGGQMGGLSGTTTVNITLTDVNNNPPRFPQSTYQFNSPESVPLGTHLGRIKANDPD 296
QAKDMGGQMGGLSGTTTVNITLTDVN+NPPRFPQ+T ES P+GT +G +KA D D
Sbjct: 238 QAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNTIHLRVLESSPVGTAIGSVKATDAD 297
Query: 297 VGENAEMEYSIAEGDGADMFDVITDKDTQEGIITVKQNLDFENQMLYTLRVDASNTHPDP 356
G+NAE+EY I +GDG DMFD++T+KDTQEGIITVK+ LD+E++ LYTL+V+A NTH DP
Sbjct: 298 TGKNAEVEYRIIDGDGTDMFDIVTEKDTQEGIITVKKPLDYESRRLYTLKVEAENTHVDP 357
Query: 357 RFLHLGPFKDTAVVKISVEDIDEPPVFTKVSYLIEVDEDVKEGSIIGQVTAYDPDARNNL 416
RF +LGPFKDT +VKIS+ED+DEPPVF++ SYL EV ED++ G+IIG V A DPD+ ++
Sbjct: 358 RFYYLGPFKDTTIVKISIEDVDEPPVFSRSSYLFEVHEDIEVGTIIGTVMARDPDSISSP 417
Query: 417 IKYSVDRHTDMDRIFGIHSENGSIFTLKALDRESSPWHNITVTATEINNPKQSSHIPVFI 476
I++S+DRHTD+DRIF IHS NGS++T K LDRE S WHN+TV A EINNPK+++ + VF+
Sbjct: 418 IRFSLDRHTDLDRIFNIHSGNGSLYTSKPLDRELSQWHNLTVIAAEINNPKETTRVAVFV 477
Query: 477 RILDINDHAPEFAMYYETFVCENAKPGQLIQTVSVMDKDDPPRGHKFFFEPVPEFTLNPN 536
RILD+ND+AP+FA++Y+TFVCENA+PGQLIQT+S +DKDDP G KFFF +NPN
Sbjct: 478 RILDVNDNAPQFAVFYDTFVCENARPGQLIQTISAVDKDDPLGGQKFFFSLA---AVNPN 534
Query: 537 FTIVDNKDNTAGIMTRKDGYSRNKMSTYLLPILIFDNDYPIQSSTGTLTIRVCACDNQGN 596
FT+ DN+DNTA I+TRK+G++R+++STYLLP++I DNDYPIQSSTGTLTIRVCACD+QGN
Sbjct: 535 FTVQDNEDNTARILTRKNGFNRHEISTYLLPVVISDNDYPIQSSTGTLTIRVCACDSQGN 594
Query: 597 MQSCTAEALILSAGLSTGALVAILLCVLILLILVVLFAALKRQRKKEPLIISKDDVRDNI 656
MQSC+AEAL+L AGLSTGAL+AILLC++ILL++VVLFAALKRQRKKEPLI+SK+D+RDNI
Sbjct: 595 MQSCSAEALLLPAGLSTGALIAILLCIIILLVIVVLFAALKRQRKKEPLILSKEDIRDNI 654
Query: 657 VTYNDEGGGEEDTQAFDIGTLRNPEAREDSKLRRDVMPETIFQIRRTVPLWENIDVQDFI 716
V+YNDEGGGEEDTQAFDIGTLRNP A E+ KLRRD++PET+F RRT +N DV+DFI
Sbjct: 655 VSYNDEGGGEEDTQAFDIGTLRNPAAIEEKKLRRDIIPETLFIPRRTPTAPDNTDVRDFI 714
Query: 717 HRRLKENDADPSAPPYDSLATYAYEGNDSIADSLSSLESLTADCNQDYDYLSDWGPRFKK 776
+ RLKE+D DP+APPYDSLATYAYEGNDSIA+SLSSLES T + +Q+YDYL +WGPRF K
Sbjct: 715 NERLKEHDLDPTAPPYDSLATYAYEGNDSIAESLSSLESGTTEGDQNYDYLREWGPRFNK 774
Query: 777 LADMYGGDDSDRD 789
LA+MYGG +SD+D
Sbjct: 775 LAEMYGGGESDKD 787
>gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens]
Length = 794
Score = 948 bits (2451), Expect = 0.0
Identities = 454/788 (57%), Positives = 603/788 (76%), Gaps = 3/788 (0%)
Query: 1 MRTYHYIPLFIWTYMFHTVDTILLQEKPNSYLSSKKIAGLTKDDGKM--LRRTKRGWMWN 58
M T + + L +W +F LQ +P L+++ + G+ +R KRGW+WN
Sbjct: 1 MLTRNCLSLLLWV-LFDGGLLTPLQPQPQQTLATEPRENVIHLPGQRSHFQRVKRGWVWN 59
Query: 59 QFFLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILTGDGAGSLFVIDENTGDIHAAKKLDR 118
QFF+LEEY G++ QYVGKLH+D DKG+G +KY L+GDGAG++F IDE TGDIHA + LDR
Sbjct: 60 QFFVLEEYVGSEPQYVGKLHSDLDKGEGTVKYTLSGDGAGTVFTIDETTGDIHAIRSLDR 119
Query: 119 EEKSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTKDLYTASVPEMSGVGTSV 178
EEK Y LRA+A+D +T + +EPESEFIIK+ DINDNEPKF Y A+VPEMS VG V
Sbjct: 120 EEKPFYTLRAQAVDIETRKPLEPESEFIIKVQDINDNEPKFLDGPYVATVPEMSPVGAYV 179
Query: 179 IQVTATDADDANYGNSAKVVYSILQGQPYFSVDPESGIIKTALPDMSRENREQYQVVIQA 238
+QV ATDADD YGNSA+VVYSILQGQPYFS+DP++G+I+TALP+M RE +EQYQV+IQA
Sbjct: 180 LQVKATDADDPTYGNSARVVYSILQGQPYFSIDPKTGVIRTALPNMDREVKEQYQVLIQA 239
Query: 239 KDMGGQMGGLSGTTTVNITLTDVNNNPPRFPQSTYQFNSPESVPLGTHLGRIKANDPDVG 298
KDMGGQ+GGL+GTT VNITLTDVN+NPPRFP+S + PES P+G+ +GRI+A DPD G
Sbjct: 240 KDMGGQLGGLAGTTIVNITLTDVNDNPPRFPKSIFHLKVPESSPIGSAIGRIRAVDPDFG 299
Query: 299 ENAEMEYSIAEGDGADMFDVITDKDTQEGIITVKQNLDFENQMLYTLRVDASNTHPDPRF 358
+NAE+EY+I GDG ++FD++TD+DTQEG+I +K+ LDFE + YT +V+ASN H D RF
Sbjct: 300 QNAEIEYNIVPGDGGNLFDIVTDEDTQEGVIKLKKPLDFETKKAYTFKVEASNLHLDHRF 359
Query: 359 LHLGPFKDTAVVKISVEDIDEPPVFTKVSYLIEVDEDVKEGSIIGQVTAYDPDARNNLIK 418
GPFKDTA VKISV D+DEPPVF+K Y +EV ED G+IIG VTA D D ++ ++
Sbjct: 360 HSAGPFKDTATVKISVLDVDEPPVFSKPLYTMEVYEDTPVGTIIGAVTAQDLDVGSSAVR 419
Query: 419 YSVDRHTDMDRIFGIHSENGSIFTLKALDRESSPWHNITVTATEINNPKQSSHIPVFIRI 478
Y +D +D D F I G+I T + LDRES+ +N ++ A++++NP +S + + I +
Sbjct: 420 YFIDWKSDGDSYFTIDGNEGTIATNELLDRESTAQYNFSIIASKVSNPLLTSKVNILINV 479
Query: 479 LDINDHAPEFAMYYETFVCENAKPGQLIQTVSVMDKDDPPRGHKFFFEPVPEFTLNPNFT 538
LD+N+ PE ++ YET VCENAKPGQ+IQ VS D+D P G +F F PE + PNFT
Sbjct: 480 LDVNEFPPEISVPYETAVCENAKPGQIIQIVSAADRDLSPAGQQFSFRLSPEAAIKPNFT 539
Query: 539 IVDNKDNTAGIMTRKDGYSRNKMSTYLLPILIFDNDYPIQSSTGTLTIRVCACDNQGNMQ 598
+ D ++NTAGI TR++GYSR + Y LP++I D+ YP+QSST T+TIRVC CD+ G +
Sbjct: 540 VRDFRNNTAGIETRRNGYSRRQQELYFLPVVIEDSSYPVQSSTNTMTIRVCRCDSDGTIL 599
Query: 599 SCTAEALILSAGLSTGALVAILLCVLILLILVVLFAALKRQRKKEPLIISKDDVRDNIVT 658
SC EA+ L GLSTGAL+AILLC++ILL +VVL+ AL+RQ+KK+ L+ SK+D+RDN++
Sbjct: 600 SCNVEAIFLPVGLSTGALIAILLCIVILLAIVVLYVALRRQKKKDTLMTSKEDIRDNVIH 659
Query: 659 YNDEGGGEEDTQAFDIGTLRNPEAREDSKLRRDVMPETIFQIRRTVPLWENIDVQDFIHR 718
Y+DEGGGEEDTQAFDIG LRNP+ E++K+RRD+ P+++ R+ P+ +N D++DFIH+
Sbjct: 660 YDDEGGGEEDTQAFDIGALRNPKVIEENKIRRDIKPDSLCLPRQRPPMEDNTDIRDFIHQ 719
Query: 719 RLKENDADPSAPPYDSLATYAYEGNDSIADSLSSLESLTADCNQDYDYLSDWGPRFKKLA 778
RL+END DP+APPYDSLATYAYEG+ S+A+SLSS++SLT + +QDYDYL+DWGPRFK LA
Sbjct: 720 RLQENDVDPTAPPYDSLATYAYEGSGSVAESLSSIDSLTTEADQDYDYLTDWGPRFKVLA 779
Query: 779 DMYGGDDS 786
DM+G ++S
Sbjct: 780 DMFGEEES 787
>gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens]
Length = 785
Score = 934 bits (2414), Expect = 0.0
Identities = 458/737 (62%), Positives = 577/737 (78%), Gaps = 7/737 (0%)
Query: 50 RTKRGWMWNQFFLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILTGDGAGSLFVIDENTGD 109
RTKR W+WNQFF+LEEY G+D YVGKLH+D DKGDG++KYIL+G+GA S+F+IDENTGD
Sbjct: 44 RTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSGEGASSIFIIDENTGD 103
Query: 110 IHAAKKLDREEKSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTKDLYTASVP 169
IHA K+LDREE++ Y LRA+A+DR T + VEPESEF+IKI DINDNEPKF YTA VP
Sbjct: 104 IHATKRLDREEQAYYTLRAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLDGPYTAGVP 163
Query: 170 EMSGVGTSVIQVTATDADDANYGNSAKVVYSILQGQPYFSVDPESGIIKTALPDMSRENR 229
EMS VGTSV+QVTATDADD YGNSA+VVYSILQGQPYFSV+P++G+IKTALP+M RE +
Sbjct: 164 EMSPVGTSVVQVTATDADDPTYGNSARVVYSILQGQPYFSVEPKTGVIKTALPNMDREAK 223
Query: 230 EQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNNNPPRFPQSTYQFNSPESVPLGTHLGR 289
+QY +VIQAKDM GQ GGLSGTT+V +TLTDVN+NPPRFP+ +YQ+N PES+P+ + + R
Sbjct: 224 DQYLLVIQAKDMVGQNGGLSGTTSVTVTLTDVNDNPPRFPRRSYQYNVPESLPVASVVAR 283
Query: 290 IKANDPDVGENAEMEYSIAEGDGADMFDVITDKDTQEGIITVKQNLDFENQMLYTLRVDA 349
IKA D D+G NAEMEY I +GDG +F + DK+TQEGIIT+++ LDFE + YTLR++A
Sbjct: 284 IKAADADIGANAEMEYKIVDGDGLGIFKISVDKETQEGIITIQKELDFEAKTSYTLRIEA 343
Query: 350 SNTHPDPRFLHLGPFKDTAVVKISVEDIDEPPVFTKVSYLIEVDEDVKEGSIIGQVTAYD 409
+N DPRFL LGPF DT VKI VED+DEPPVF+ Y +EV E + G+IIG V A+D
Sbjct: 344 ANKDADPRFLSLGPFSDTTTVKIIVEDVDEPPVFSSPLYPMEVSEATQVGNIIGTVAAHD 403
Query: 410 PDARNNLIKYSVDRHTDMDRIFGIHSENGSIFTLKALDRESSPWHNITVTATEINNPKQS 469
PD+ N+ ++YS+DR+TD++R F I + +G I T K+LDRE++ HNITV A E NP Q
Sbjct: 404 PDSSNSPVRYSIDRNTDLERYFNIDANSGVITTAKSLDRETNAIHNITVLAMESQNPSQV 463
Query: 470 SHIPVFIRILDINDHAPEFAMYYETFVCENAKPGQLIQTVSVMDKDDPPRGHKFFFEPVP 529
V I ILDIND+APEFAM YET VCENA+PGQ+IQ +S +DKD+P GH+F+F
Sbjct: 464 GRGYVAITILDINDNAPEFAMDYETTVCENAQPGQVIQKISAVDKDEPSNGHQFYFSLTT 523
Query: 530 EFTLNPNFTIVDNKDNTAGIMTRKDGYSRNKMSTYLLPILIFDNDYPIQSSTGTLTIRVC 589
+ T N NF++ DNKDNTA I+TR++G+ R + S Y LPI I D+ P SST TLTIRVC
Sbjct: 524 DATNNHNFSLKDNKDNTASILTRRNGFRRQEQSVYYLPIFIVDSGSPSLSSTNTLTIRVC 583
Query: 590 ACDNQGNMQSCTAEALILSAGLSTGALVAILLCVLILLILVVLFAALKRQRKKEPLIISK 649
CD G Q+C AEA +L AGLSTGAL+AIL CVL LL+L++L ++R RKKEPLI +
Sbjct: 584 DCDADGVAQTCNAEAYVLPAGLSTGALIAILACVLTLLVLILLIVTMRR-RKKEPLIFDE 642
Query: 650 D-DVRDNIVTYNDEGGGEEDTQAFDIGTLRNPEAREDSKLRRDVMPETIFQIR---RTVP 705
+ D+R+NIV Y+DEGGGEEDT+AFD+ LRN D+K RRDV PE F R +++P
Sbjct: 643 ERDIRENIVRYDDEGGGEEDTEAFDMAALRNLNVIRDTKTRRDVTPEIQFLSRPAFKSIP 702
Query: 706 LWENIDVQDFIHRRLKENDADPSAPPYDSLATYAYEGNDSIADSLSSLESLTADCNQDYD 765
+N+ ++FI RLKE D DP APPYDSL TYA+EGN S+A+SLSSL+S++++ +Q+YD
Sbjct: 703 --DNVIFREFIWERLKEADVDPGAPPYDSLQTYAFEGNGSVAESLSSLDSISSNSDQNYD 760
Query: 766 YLSDWGPRFKKLADMYG 782
YLSDWGPRFK+LADMYG
Sbjct: 761 YLSDWGPRFKRLADMYG 777
>gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens]
Length = 785
Score = 934 bits (2414), Expect = 0.0
Identities = 458/737 (62%), Positives = 577/737 (78%), Gaps = 7/737 (0%)
Query: 50 RTKRGWMWNQFFLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILTGDGAGSLFVIDENTGD 109
RTKR W+WNQFF+LEEY G+D YVGKLH+D DKGDG++KYIL+G+GA S+F+IDENTGD
Sbjct: 44 RTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSGEGASSIFIIDENTGD 103
Query: 110 IHAAKKLDREEKSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTKDLYTASVP 169
IHA K+LDREE++ Y LRA+A+DR T + VEPESEF+IKI DINDNEPKF YTA VP
Sbjct: 104 IHATKRLDREEQAYYTLRAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLDGPYTAGVP 163
Query: 170 EMSGVGTSVIQVTATDADDANYGNSAKVVYSILQGQPYFSVDPESGIIKTALPDMSRENR 229
EMS VGTSV+QVTATDADD YGNSA+VVYSILQGQPYFSV+P++G+IKTALP+M RE +
Sbjct: 164 EMSPVGTSVVQVTATDADDPTYGNSARVVYSILQGQPYFSVEPKTGVIKTALPNMDREAK 223
Query: 230 EQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNNNPPRFPQSTYQFNSPESVPLGTHLGR 289
+QY +VIQAKDM GQ GGLSGTT+V +TLTDVN+NPPRFP+ +YQ+N PES+P+ + + R
Sbjct: 224 DQYLLVIQAKDMVGQNGGLSGTTSVTVTLTDVNDNPPRFPRRSYQYNVPESLPVASVVAR 283
Query: 290 IKANDPDVGENAEMEYSIAEGDGADMFDVITDKDTQEGIITVKQNLDFENQMLYTLRVDA 349
IKA D D+G NAEMEY I +GDG +F + DK+TQEGIIT+++ LDFE + YTLR++A
Sbjct: 284 IKAADADIGANAEMEYKIVDGDGLGIFKISVDKETQEGIITIQKELDFEAKTSYTLRIEA 343
Query: 350 SNTHPDPRFLHLGPFKDTAVVKISVEDIDEPPVFTKVSYLIEVDEDVKEGSIIGQVTAYD 409
+N DPRFL LGPF DT VKI VED+DEPPVF+ Y +EV E + G+IIG V A+D
Sbjct: 344 ANKDADPRFLSLGPFSDTTTVKIIVEDVDEPPVFSSPLYPMEVSEATQVGNIIGTVAAHD 403
Query: 410 PDARNNLIKYSVDRHTDMDRIFGIHSENGSIFTLKALDRESSPWHNITVTATEINNPKQS 469
PD+ N+ ++YS+DR+TD++R F I + +G I T K+LDRE++ HNITV A E NP Q
Sbjct: 404 PDSSNSPVRYSIDRNTDLERYFNIDANSGVITTAKSLDRETNAIHNITVLAMESQNPSQV 463
Query: 470 SHIPVFIRILDINDHAPEFAMYYETFVCENAKPGQLIQTVSVMDKDDPPRGHKFFFEPVP 529
V I ILDIND+APEFAM YET VCENA+PGQ+IQ +S +DKD+P GH+F+F
Sbjct: 464 GRGYVAITILDINDNAPEFAMDYETTVCENAQPGQVIQKISAVDKDEPSNGHQFYFSLTT 523
Query: 530 EFTLNPNFTIVDNKDNTAGIMTRKDGYSRNKMSTYLLPILIFDNDYPIQSSTGTLTIRVC 589
+ T N NF++ DNKDNTA I+TR++G+ R + S Y LPI I D+ P SST TLTIRVC
Sbjct: 524 DATNNHNFSLKDNKDNTASILTRRNGFRRQEQSVYYLPIFIVDSGSPSLSSTNTLTIRVC 583
Query: 590 ACDNQGNMQSCTAEALILSAGLSTGALVAILLCVLILLILVVLFAALKRQRKKEPLIISK 649
CD G Q+C AEA +L AGLSTGAL+AIL CVL LL+L++L ++R RKKEPLI +
Sbjct: 584 DCDADGVAQTCNAEAYVLPAGLSTGALIAILACVLTLLVLILLIVTMRR-RKKEPLIFDE 642
Query: 650 D-DVRDNIVTYNDEGGGEEDTQAFDIGTLRNPEAREDSKLRRDVMPETIFQIR---RTVP 705
+ D+R+NIV Y+DEGGGEEDT+AFD+ LRN D+K RRDV PE F R +++P
Sbjct: 643 ERDIRENIVRYDDEGGGEEDTEAFDMAALRNLNVIRDTKTRRDVTPEIQFLSRPAFKSIP 702
Query: 706 LWENIDVQDFIHRRLKENDADPSAPPYDSLATYAYEGNDSIADSLSSLESLTADCNQDYD 765
+N+ ++FI RLKE D DP APPYDSL TYA+EGN S+A+SLSSL+S++++ +Q+YD
Sbjct: 703 --DNVIFREFIWERLKEADVDPGAPPYDSLQTYAFEGNGSVAESLSSLDSISSNSDQNYD 760
Query: 766 YLSDWGPRFKKLADMYG 782
YLSDWGPRFK+LADMYG
Sbjct: 761 YLSDWGPRFKRLADMYG 777
>gi|4826671 cadherin 18, type 2 preproprotein [Homo sapiens]
Length = 790
Score = 921 bits (2381), Expect = 0.0
Identities = 449/740 (60%), Positives = 569/740 (76%), Gaps = 2/740 (0%)
Query: 50 RTKRGWMWNQFFLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILTGDGAGSLFVIDENTGD 109
R KRGW+WNQFF+LEE+ G D QYVGKLH++ DKGDG++KYILTG+GAG++F+ID+ TGD
Sbjct: 50 RPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAGTIFIIDDTTGD 109
Query: 110 IHAAKKLDREEKSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTKDLYTASVP 169
IH+ K LDRE+K+ Y+L A+AIDR+T + +EPESEFIIK+ DINDN PKFT Y +VP
Sbjct: 110 IHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYIVTVP 169
Query: 170 EMSGVGTSVIQVTATDADDANYGNSAKVVYSILQGQPYFSVDPESGIIKTALPDMSRENR 229
EMS +GTSV+QVTATDADD YGNSA+VVYSILQGQPYFSVDP++G+I+TAL +M RE R
Sbjct: 170 EMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQPYFSVDPKTGVIRTALHNMDREAR 229
Query: 230 EQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNNNPPRFPQSTYQFNSPESVPLGTHLGR 289
E Y VVIQAKDM GQ+GGLSG+TTVNITLTDVN+NPPRFPQ YQ PES +G+ +G+
Sbjct: 230 EHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVPESAQVGSAVGK 289
Query: 290 IKANDPDVGENAEMEYSIAEGDGADMFDVITDKDTQEGIITVKQNLDFENQMLYTLRVDA 349
IKAND D G NA+M YSI GDG +F + TDK+T+EGI+++K+ L++E + YTL ++
Sbjct: 290 IKANDADTGSNADMTYSIINGDGMGIFSISTDKETREGILSLKKPLNYEKKKSYTLNIEG 349
Query: 350 SNTHPDPRFLHLGPFKDTAVVKISVEDIDEPPVFTKVSYLIEVDEDVKEGSIIGQVTAYD 409
+NTH D RF HLGPFKD ++KI V D+DEPP+F+ SYL+EV E+ K G+++G V A D
Sbjct: 350 ANTHLDFRFSHLGPFKDATMLKIIVGDVDEPPLFSMPSYLMEVYENAKIGTVVGTVLAQD 409
Query: 410 PDARNNLIKYSVDRHTDMDRIFGIHSENGSIFTLKALDRESSPWHNITVTATEINNPKQS 469
PD+ N+L++Y ++ + + DR F I + G+I T K LDRE +PW+NITVTA+EI+NP
Sbjct: 410 PDSTNSLVRYFINYNVEDDRFFNIDANTGTIRTTKVLDREETPWYNITVTASEIDNPDLL 469
Query: 470 SHIPVFIRILDINDHAPEFAMYYETFVCENAKPGQLIQTVSVMDKDDPPRGHKFFFEPVP 529
SH+ V IR+LD+ND+ PE A Y+ VCEN+KPGQ+I T+S DKDD G +F F
Sbjct: 470 SHVTVGIRVLDVNDNPPELAREYDIIVCENSKPGQVIHTISATDKDDFANGPRFNFFLDE 529
Query: 530 EFTLNPNFTIVDNKDNTAGIMTRKDGYSRNKMSTYLLPILIFDNDYPIQSSTGTLTIRVC 589
+NPNFT+ DN+DNTA I+TR+ +SR Y LPI+I D P SS+ TLTIRVC
Sbjct: 530 RLPVNPNFTLKDNEDNTASILTRRRRFSRTVQDVYYLPIMISDGGIPSLSSSSTLTIRVC 589
Query: 590 ACDNQGNMQSCTAEALILSAGLSTGALVAILLCVLILLILVVLFAALKRQRKKEPLIISK 649
AC+ G +++C AEA + SAGLSTGAL+AILLCVLILL +VVLF L+R KKEPLIIS+
Sbjct: 590 ACERDGRVRTCHAEAFLSSAGLSTGALIAILLCVLILLAIVVLFITLRRS-KKEPLIISE 648
Query: 650 DDVRDNIVTYNDEGGGEEDTQAFDIGTLRNPEAREDSKLRRDVMPETIFQIR-RTVPLWE 708
+DVR+N+VTY+DEGGGEEDT+AFDI LRNP A E+ K RRD+ PE R +T E
Sbjct: 649 EDVRENVVTYDDEGGGEEDTEAFDITALRNPSAAEELKYRRDIRPEVKLTPRHQTSSTLE 708
Query: 709 NIDVQDFIHRRLKENDADPSAPPYDSLATYAYEGNDSIADSLSSLESLTADCNQDYDYLS 768
+IDVQ+FI +RL E D DPS PPYDSL TYAYEG S A S+SSL+S T +QDY YL
Sbjct: 709 SIDVQEFIKQRLAEADLDPSVPPYDSLQTYAYEGQRSEAGSISSLDSATTQSDQDYHYLG 768
Query: 769 DWGPRFKKLADMYGGDDSDR 788
DWGP FKKLA++YG +S+R
Sbjct: 769 DWGPEFKKLAELYGEIESER 788
>gi|16306532 cadherin 11, type 2 preproprotein [Homo sapiens]
Length = 796
Score = 904 bits (2336), Expect = 0.0
Identities = 437/751 (58%), Positives = 568/751 (75%), Gaps = 5/751 (0%)
Query: 44 DGKMLRRTKRGWMWNQFFLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILTGDGAGSLFVI 103
+G++L+R+KRGW+WNQFF++EEYTG D VG+LH+D D GDGN+KYIL+G+GAG++FVI
Sbjct: 44 EGQVLQRSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVI 103
Query: 104 DENTGDIHAAKKLDREEKSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTKDL 163
D+ +G+IHA K LDREE++ Y L A+A+DR T R +EP SEFI+K+ DINDN P+F +
Sbjct: 104 DDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHET 163
Query: 164 YTASVPEMSGVGTSVIQVTATDADDANYGNSAKVVYSILQGQPYFSVDPESGIIKTALPD 223
Y A+VPE S VGTSVIQVTA+DADD YGNSAK+VYSIL+GQPYFSV+ ++GII+TALP+
Sbjct: 164 YHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPN 223
Query: 224 MSRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNNNPPRFPQSTYQFNSPESVPL 283
M RE +E+Y VVIQAKDMGG MGGLSGTT V ITLTDVN+NPP+FPQS YQ + E+
Sbjct: 224 MDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVP 283
Query: 284 GTHLGRIKANDPDVGENAEMEYSIAEGDGADMFDVITDKDTQEGIITVKQNLDFENQMLY 343
G +GR+KA DPD+GEN + Y+I +GDG + F++ TD +TQEG+I +K+ +DFE + Y
Sbjct: 284 GEEVGRVKAKDPDIGENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAY 343
Query: 344 TLRVDASNTHPDPRFLHLGPFKDTAVVKISVEDIDEPPVFTKVSYLIEVDEDVKEGSIIG 403
+L+V+A+N H DP+F+ GPFKDT VKISVED DEPP+F SY+ EV E+ G+++G
Sbjct: 344 SLKVEAANVHIDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQENAAAGTVVG 403
Query: 404 QVTAYDPDARNNLIKYSVDRHTDMDRIFGIHSENGSIFTLKALDRESSPWHNITVTATEI 463
+V A DPDA N+ I+YS+DRHTD+DR F I+ E+G I T K LDRE + W NITV A EI
Sbjct: 404 RVHAKDPDAANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEI 463
Query: 464 NNPKQSSHIPVFIRILDINDHAPEFAMYYETFVCEN--AKP--GQLIQTVSVMDKDDPPR 519
+N Q + +PV IR+LD+ND+AP+FA YE F+CE+ KP Q I T+S DKDD
Sbjct: 464 HNRHQEAKVPVAIRVLDVNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTAN 523
Query: 520 GHKFFFEPVPEFTLNPNFTIVDNKDNTAGIMTRKDGYSRNKMSTYLLPILIFDNDYPIQS 579
G +F F PE NPNFT+ DN+DNTAG+ R+ G+SR K YLLPI+I D P S
Sbjct: 524 GPRFIFSLPPEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMS 583
Query: 580 STGTLTIRVCACDNQGNMQSCTAEALILSAGLSTGALVAILLCVLILLILVVLFAALKRQ 639
ST TLTI+VC CD G + SC AEA IL+AGLSTGAL+AIL C++ILL++VVLF L+RQ
Sbjct: 584 STNTLTIKVCGCDVNGALLSCNAEAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQ 643
Query: 640 RKKEPLIISKDDVRDNIVTYNDEGGGEEDTQAFDIGTLRNPEAREDSKLRRDVMPETIFQ 699
+K+ ++ ++DVR+NI+TY+DEGGGEEDT+AFDI TL+NP+ R+D+ PE +
Sbjct: 644 KKEPLIVFEEEDVRENIITYDDEGGGEEDTEAFDIATLQNPDGINGFIPRKDIKPEYQYM 703
Query: 700 IRRTV-PLWENIDVQDFIHRRLKENDADPSAPPYDSLATYAYEGNDSIADSLSSLESLTA 758
R + P ++DV DFI+ R++E D DP+APPYDS+ Y YEG S+A SLSSLES T
Sbjct: 704 PRPGLRPAPNSVDVDDFINTRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATT 763
Query: 759 DCNQDYDYLSDWGPRFKKLADMYGGDDSDRD 789
D + DYDYL +WGPRFKKLAD+YG D+ D
Sbjct: 764 DSDLDYDYLQNWGPRFKKLADLYGSKDTFDD 794
>gi|16306539 cadherin 8, type 2 preproprotein [Homo sapiens]
Length = 799
Score = 896 bits (2316), Expect = 0.0
Identities = 434/749 (57%), Positives = 563/749 (75%), Gaps = 3/749 (0%)
Query: 43 DDGKMLRRTKRGWMWNQFFLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILTGDGAGSLFV 102
++ ++L R+KRGW+WNQ F+LEE++G + VG+LHTD D G +KYIL+GDGAG++F
Sbjct: 51 EEQRILNRSKRGWVWNQMFVLEEFSGPEPILVGRLHTDLDPGSKKIKYILSGDGAGTIFQ 110
Query: 103 IDENTGDIHAAKKLDREEKSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTKD 162
I++ TGDIHA K+LDREEK+ Y L A+A+D +T + +EP SEFIIK+ DINDN P+F
Sbjct: 111 INDVTGDIHAIKRLDREEKAEYTLTAQAVDWETSKPLEPPSEFIIKVQDINDNAPEFLNG 170
Query: 163 LYTASVPEMSGVGTSVIQVTATDADDANYGNSAKVVYSILQGQPYFSVDPESGIIKTALP 222
Y A+VPEMS +GTSV VTATDADD YGNSAK+VYSIL+GQPYFS++PE+ IIKTALP
Sbjct: 171 PYHATVPEMSILGTSVTNVTATDADDPVYGNSAKLVYSILEGQPYFSIEPETAIIKTALP 230
Query: 223 DMSRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNNNPPRFPQSTYQFNSPESVP 282
+M RE +E+Y VVIQAKDMGG GGLSGTTT+ +TLTDVN+NPP+F QS Y F+ PE V
Sbjct: 231 NMDREAKEEYLVVIQAKDMGGHSGGLSGTTTLTVTLTDVNDNPPKFAQSLYHFSVPEDVV 290
Query: 283 LGTHLGRIKANDPDVGENAEMEYSIAEGDGADMFDVITDKDTQEGIITVKQNLDFENQML 342
LGT +GR+KAND D+GENA+ Y I +GDG +F++ +D Q+GII +++ LDFE +
Sbjct: 291 LGTAIGRVKANDQDIGENAQSSYDIIDGDGTALFEITSDAQAQDGIIRLRKPLDFETKKS 350
Query: 343 YTLRVDASNTHPDPRFLHLGPFKDTAVVKISVEDIDEPPVFTKVSYLIEVDEDVKEGSII 402
YTL+V+A+N H DPRF GPFKDTA VKI VED DEPPVF+ +YL+EV E+ S+I
Sbjct: 351 YTLKVEAANVHIDPRFSGRGPFKDTATVKIVVEDADEPPVFSSPTYLLEVHENAALNSVI 410
Query: 403 GQVTAYDPDARNNLIKYSVDRHTDMDRIFGIHSENGSIFTLKALDRESSPWHNITVTATE 462
GQVTA DPD ++ I++S+DRHTD++R F I++++G I LDRE S WHNIT+ ATE
Sbjct: 411 GQVTARDPDITSSPIRFSIDRHTDLERQFNINADDGKITLATPLDRELSVWHNITIIATE 470
Query: 463 INNPKQSSHIPVFIRILDINDHAPEFAMYYETFVCENAKPGQLIQTVSVMDKDDPPRGHK 522
I N Q S +PV I++LD+ND+APEFA YE F+CEN KPGQ+IQTVS MDKDDP GH
Sbjct: 471 IRNHSQISRVPVAIKVLDVNDNAPEFASEYEAFLCENGKPGQVIQTVSAMDKDDPKNGHY 530
Query: 523 FFFEPVPEFTLNPNFTIVDNKDNTAGIMTRKDGYSRNKMSTYLLPILIFDNDYPIQSSTG 582
F + +PE NPNFTI N+DN+ I+ + +G++R K YLLPI+I D+ P SST
Sbjct: 531 FLYSLLPEMVNNPNFTIKKNEDNSLSILAKHNGFNRQKQEVYLLPIIISDSGNPPLSSTS 590
Query: 583 TLTIRVCACDNQGNMQSCTAEALILSAGLSTGALVAILLCVLILLILVVLFAALKRQRKK 642
TLTIRVC C N G +QSC EA +L GLS GAL+AIL C+++LL++VVLF L+R K
Sbjct: 591 TLTIRVCGCSNDGVVQSCNVEAYVLPIGLSMGALIAILACIILLLVIVVLFVTLRRH-KN 649
Query: 643 EPLIISKD-DVRDNIVTYNDEGGGEEDTQAFDIGTLRNPEAREDSKLRRDVMPETIFQIR 701
EPLII D DVR+NI+ Y+DEGGGEEDT+AFDI TL+NP+ R+D+ P+ F R
Sbjct: 650 EPLIIKDDEDVRENIIRYDDEGGGEEDTEAFDIATLQNPDGINGFLPRKDIKPDLQFMPR 709
Query: 702 R-TVPLWENIDVQDFIHRRLKENDADPSAPPYDSLATYAYEGNDSIADSLSSLESLTADC 760
+ P+ +DV +FI+ RL E D DP+APPYDS+ Y YEG S+A SLSSLES T+D
Sbjct: 710 QGLAPVPNGVDVDEFINVRLHEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESTTSDS 769
Query: 761 NQDYDYLSDWGPRFKKLADMYGGDDSDRD 789
+Q++DYLSDWGPRFK+L ++Y +SD++
Sbjct: 770 DQNFDYLSDWGPRFKRLGELYSVGESDKE 798
>gi|16306537 cadherin 20, type 2 preproprotein [Homo sapiens]
Length = 801
Score = 889 bits (2298), Expect = 0.0
Identities = 441/782 (56%), Positives = 577/782 (73%), Gaps = 11/782 (1%)
Query: 9 LFIWTYMFHTVDTILLQEKPNSYLSSKKIAGLTKDDGKMLRRTKRGWMWNQFFLLEEYTG 68
L+ W M T T +L + P ++ L D + +RTKR W+WNQFF+LEEYTG
Sbjct: 20 LYFWGLMDLT--TTVLSDTPTP---QGELEALLSDKPQSHQRTKRSWVWNQFFVLEEYTG 74
Query: 69 TDTQYVGKLHTDQDKGDGNLKYILTGDGAGSLFVIDENTGDIHAAKKLDREEKSLYILRA 128
TD YVGKLH+D D+GDG++KYIL+G+GAG +F ID+ TGDIHA ++LDREE++ Y LRA
Sbjct: 75 TDPLYVGKLHSDMDRGDGSIKYILSGEGAGIVFTIDDTTGDIHAIQRLDREERAQYTLRA 134
Query: 129 KAIDRKTGRQVEPESEFIIKIHDINDNEPKFTKDLYTASVPEMSGVGTSVIQVTATDADD 188
+A+DR+TGR +EPESEFIIKI DINDNEPKF Y A+VPEMS VGTSVIQVTATDADD
Sbjct: 135 QALDRRTGRPMEPESEFIIKIQDINDNEPKFLDGPYVATVPEMSPVGTSVIQVTATDADD 194
Query: 189 ANYGNSAKVVYSILQGQPYFSVDPESGIIKTALPDMSRENREQYQVVIQAKDMGGQMGGL 248
YGNSA+VVYSILQGQPYFSVD ++G+I+TAL +M RE +E Y+V+IQAKDMGGQ+GGL
Sbjct: 195 PTYGNSARVVYSILQGQPYFSVDSKTGVIRTALMNMDREAKEYYEVIIQAKDMGGQLGGL 254
Query: 249 SGTTTVNITLTDVNNNPPRFPQSTYQFNSPESVPLGTHLGRIKANDPDVGENAEMEYSIA 308
+GTTTVNITL+DVN+NPPRFPQ YQ + ES P+ + +GR+ A D D G NAEM+Y+I
Sbjct: 255 AGTTTVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKDLDEGINAEMKYTIV 314
Query: 309 EGDGADMFDVITDKDTQEGIITVKQNLDFENQMLYTLRVDASNTHPDPRFLHLGPFKDTA 368
+GDGAD FD+ TD + Q GIITVK+ L FE++ YTL+V+ +N H + RFL+LGPF+DT
Sbjct: 315 DGDGADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKVEGANPHLEMRFLNLGPFQDTT 374
Query: 369 VVKISVEDIDEPPVFTKVSYLIEVDEDVKEGSIIGQVTAYDPDARNNLIKYSVDRHTDMD 428
V ISVED+DEPPVF Y +EV EDV G+ I ++A DPD NN I+YS+DR +D
Sbjct: 375 TVHISVEDVDEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDVTNNSIRYSIDRSSDPG 434
Query: 429 RIFGIHSENGSIFTLKALDRESSPWHNITVTATEINNPKQSSHIPVFIRILDINDHAPEF 488
R F + G++ T + LDRE WHNITV A E+NNP Q +PV I++LD+ND+APEF
Sbjct: 435 RFFYVDITTGALMTARPLDREEFSWHNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPEF 494
Query: 489 AMYYETFVCENAKPGQLIQTVSVMDKDDPPRGHKFFFEPVPEFTLNPNFTIVDNKDNTAG 548
+YE FVCENAK GQLIQTVS +D+DDP G F++ PE NPNFTI DN+DNTA
Sbjct: 495 PRFYEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQDNTAR 554
Query: 549 IMTRKDGYSRNKMSTYLLPILIFDNDYPIQSSTGTLTIRVCACDNQGNMQSCTAEALILS 608
I+TR+ G+ + + S + LPILI D+ P+ SSTGTLTI+VC+CD+ G++ SC+ EA +L
Sbjct: 555 ILTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDDGHVMSCSPEAYMLP 614
Query: 609 AGLSTGALVAILLCVLILLILVVLFAALKRQRKKEPLIISKDDVRDNIVTYNDEGGGEED 668
LS GAL+AIL C+ +LL+LV+L +++R RK+ +I ++++ +NIV Y+DEGGGEED
Sbjct: 615 VSLSRGALIAILACIFVLLVLVLLILSMRRHRKQPYIIDDEENIHENIVRYDDEGGGEED 674
Query: 669 TQAFDIGTLRNP---EAREDSKLRRDVMPETIFQIRRTVP--LWENIDVQDFIHRRLKEN 723
T+AFDI + NP +A K R+D++PE I + R VP N V ++ +L E
Sbjct: 675 TEAFDIAAMWNPREAQAGAAPKTRQDMLPE-IESLSRYVPQTCAVNSTVHSYVLAKLYEA 733
Query: 724 DADPSAPPYDSLATYAYEGNDSIADSLSSLESLTADCNQDYDYLSDWGPRFKKLADMYGG 783
D D APP+DSL TY +EG+ S+A SLSSL+S T+D Q +D+L+DWGPRF+KLA++YG
Sbjct: 734 DMDLWAPPFDSLQTYMFEGDGSVAGSLSSLQSATSDSEQSFDFLTDWGPRFRKLAELYGA 793
Query: 784 DD 785
+
Sbjct: 794 SE 795
>gi|16753221 cadherin 22 precursor [Homo sapiens]
Length = 828
Score = 802 bits (2072), Expect = 0.0
Identities = 399/791 (50%), Positives = 544/791 (68%), Gaps = 48/791 (6%)
Query: 34 SKKIAGLTKDDGKMLRRTKRGWMWNQFFLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILT 93
S G +D R KRGW+WNQFF++EEYTGT+ YVGK+H+D D+GDG +KY ++
Sbjct: 43 SPSAPGARQDGALGAGRVKRGWVWNQFFVVEEYTGTEPLYVGKIHSDSDEGDGAIKYTIS 102
Query: 94 GDGAGSLFVIDENTGDIHAAKKLDREEKSLYILRAKAIDRKTGRQVEPESEFIIKIHDIN 153
G+GAG++F+IDE TGDIHA ++LDRE+K+ Y LRA+A DR T R +EPESEFIIK+ DIN
Sbjct: 103 GEGAGTIFLIDELTGDIHAMERLDREQKTFYTLRAQARDRATNRLLEPESEFIIKVQDIN 162
Query: 154 DNEPKFTKDLYTASVPEMSGVGTSVIQVTATDADDANYGNSAKVVYSILQGQPYFSVDPE 213
D+EP+F Y SV E+S GTSV+QV A+DADD YG+SA++VYS+L G+ +F+VDP+
Sbjct: 163 DSEPRFLHGPYIGSVAELSPTGTSVMQVMASDADDPTYGSSARLVYSVLDGEHHFTVDPK 222
Query: 214 SGIIKTALPDMSRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNNNPPRFPQSTY 273
+G+I+TA+PD+ RE++E+Y+VVIQA DM GQ+GGLSG+TTV I +TDVN+NPPRFPQ Y
Sbjct: 223 TGVIRTAVPDLDRESQERYEVVIQATDMAGQLGGLSGSTTVTIVVTDVNDNPPRFPQKMY 282
Query: 274 QFNSPESVPLGTHLGRIKANDPDVGENAEMEYSIAE--GDGADMFDVITDKDTQEGIITV 331
QF+ ES P+GT +GR+KA D DVGEN +M Y + + G D+F V TD DTQE II V
Sbjct: 283 QFSIQESAPIGTAVGRVKAEDSDVGENTDMTYHLKDESSSGGDVFKVTTDSDTQEAIIVV 342
Query: 332 KQNLDFENQMLYTLRVDASNTHPDPRFLHLGPFKDTAVVKISVEDIDEPPVFTKVSYLIE 391
++ LDFE+Q ++T+ ++A N DPRF LG F+D A+V+++V D+DEPP F S L+E
Sbjct: 343 QKRLDFESQPVHTVILEALNKFVDPRFADLGTFRDQAIVRVAVTDVDEPPEFRPPSGLLE 402
Query: 392 VDEDVKEGSIIGQVTAYDPDARNNLIKYSVDRHTDMDRIFGIHSENGSIFTLKALDRESS 451
V ED + GS++G VTA DPDA N ++Y++DR +D+D+IF I ++ G+I T K LDRE++
Sbjct: 403 VQEDAQVGSLVGVVTARDPDAANRPVRYAIDRESDLDQIFDIDADTGAIVTGKGLDRETA 462
Query: 452 PWHNITVTATEINNPKQSSHIPVFIRILDINDHAPEFAMYYETFVCENAKPGQLIQTVSV 511
WHNITV A E +N Q S + IRILD+ND+ PE A YE VCE+AKPGQLIQT+SV
Sbjct: 463 GWHNITVLAMEADNHAQLSRASLRIRILDVNDNPPELATPYEAAVCEDAKPGQLIQTISV 522
Query: 512 MDKDDPPRGHKFFFEPVPEFTLNPNFTIVDNKDNTAGIMTRKDGYSRNKMSTYLLPILIF 571
+D+D+P GH+F+F VPE NP+F+++D +DNTA + T+ G++R + + LPIL+
Sbjct: 523 VDRDEPQGGHRFYFRLVPEAPSNPHFSLLDIQDNTAAVHTQHVGFNRQEQDVFFLPILVV 582
Query: 572 DNDYPIQSSTGTLTIRVCACDNQGNMQSCTAEALILSAGLSTGALVAILLCVLILLILVV 631
D+ P SSTGTLTIR+C CD+ G +QSC A +++A LS GAL+A+L+CVLIL++LV+
Sbjct: 583 DSGPPTLSSTGTLTIRICGCDSSGTIQSCNTTAFVMAASLSPGALIALLVCVLILVVLVL 642
Query: 632 LFAALKRQRKKEPLIISKDDVRDNIVTYNDEGGGEEDTQAFDIGTLRN------------ 679
L L+R K +D+RDN++ YNDEGGGE+DT+A+D+ LR+
Sbjct: 643 LILTLRRHHKSHLSSDEDEDMRDNVIKYNDEGGGEQDTEAYDMSALRSLYDFGELKGGDG 702
Query: 680 -------------------PEAREDSKL----RRDVMPETIFQIRRTVPLWENIDVQDFI 716
P+A S+ + PE F + R DFI
Sbjct: 703 GGSAGGGAGGGSGGGAGSPPQAHLPSERHSLPQGPPSPEPDFSVFR-----------DFI 751
Query: 717 HRRLKENDADPSAPPYDSLATYAYEGNDSIADSLSSLESLTADCNQDYDYLSDWGPRFKK 776
R++ D D S PPYD+ TYA+EG DS A SLSSL S ++ QD+ YLS WGPRF+
Sbjct: 752 SRKVALADGDLSVPPYDAFQTYAFEGADSPAASLSSLHSGSSGSEQDFAYLSSWGPRFRP 811
Query: 777 LADMYGGDDSD 787
LA +Y G D
Sbjct: 812 LAALYAGHRGD 822
>gi|32880203 cadherin-like 24 isoform 2 [Homo sapiens]
Length = 781
Score = 744 bits (1922), Expect = 0.0
Identities = 375/755 (49%), Positives = 525/755 (69%), Gaps = 13/755 (1%)
Query: 38 AGLTKDDGKMLRRTKRGWMWNQFFLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILTGDGA 97
AG + G L RT+R W+WNQFF++EEY G + +GKLH+D D+G+G KY+LTG+GA
Sbjct: 29 AGSREHPGPALLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGA 88
Query: 98 GSLFVIDENTGDIHAAKKLDREEKSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEP 157
G++FVIDE TG+IH K LDREEK+ Y+L A+A+DR + R +EP SEFIIK+ DINDN P
Sbjct: 89 GTVFVIDEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPP 148
Query: 158 KFTKDLYTASVPEMSGVGTSVIQVTATDADDANYGNSAKVVYSILQGQPYFSVDPESGII 217
F Y A+VPEMS VGTSVIQVTA DADD +YGNSAK+VY++L G P+FSVDP++G++
Sbjct: 149 IFPLGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLPFFSVDPQTGVV 208
Query: 218 KTALPDMSRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNNNPPRFPQSTYQFNS 277
+TA+P+M RE +E++ VVIQAKDMGG MGGLSG+TTV +TL+DVN+NPP+FPQS YQF+
Sbjct: 209 RTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSV 268
Query: 278 PESVPLGTHLGRIKANDPDVGENAEMEYSIAEGDGADMFDVITDKDTQEGIITVKQNLDF 337
E+ GT +GR++A DPD+G+NA M YSI +G+G++ F + TD ++G++TV++ LDF
Sbjct: 269 VETAGPGTLVGRLRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDF 328
Query: 338 ENQMLYTLRVDASNTHPDPRFLHLGPFKDTAVVKISVEDIDEPPVFTKVSYLIEVDEDVK 397
E+Q Y+ RV+A+NT DP +L GPFKD A V+++V+D EPP FT+ +Y + V E+
Sbjct: 329 ESQRSYSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVPENKA 388
Query: 398 EGSIIGQVTAYDPDARNNLIKYSVDRHTDMDRIFGIHSENGSIFTLKALDRESSPWHNIT 457
G+++GQ++A D D+ + I+YS+ H+D +R F I E G+I T LDRE+ WHN+T
Sbjct: 389 PGTLVGQISAADLDSPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLT 448
Query: 458 VTATEINNPKQSSHIPVFIRILDINDHAPEFAMYYETFVCENAKPGQLIQTVSVMDKDDP 517
V ATE+++ Q+S + V I+ LD ND+AP+ A Y+TFVC++A PGQLIQ + +D+D+
Sbjct: 449 VLATELDSSAQASRVQVAIQTLDENDNAPQLAEPYDTFVCDSAAPGQLIQVIRALDRDEV 508
Query: 518 PR-GHKFFFEPVPEFTLNPNFTIVDNKDNTAGIMTRKDGYSRNKMSTYLLPILIFDNDYP 576
H F P+ + NFT+ DN+D +A ++ + + + YL+PI ++D P
Sbjct: 509 GNSSHVSFQGPLGP---DANFTVQDNRDGSASLLL-PSRPAPPRHAPYLVPIELWDWGQP 564
Query: 577 IQSSTGTLTIRVCACDNQGNMQSCTAEALILSAGLSTGALVAILLCVLILLILVVLFAAL 636
SST T+T+ VC C G++ SC EA + +AGLSTGAL+AI+ CV LL LVVLF AL
Sbjct: 565 ALSSTATVTVSVCRCQPDGSVASCWPEAHLSAAGLSTGALLAIITCVGALLALVVLFVAL 624
Query: 637 KRQRKKEPLIISKDDVRDNIVTYNDEGGGEEDTQAFDIGTLRNPEA----REDSKLRRDV 692
+RQ+++ +++ ++DVR+NI+TY+DEGGGEEDT+AFDI L+NP+ RRDV
Sbjct: 625 RRQKQEALMVLEEEDVRENIITYDDEGGGEEDTEAFDITALQNPDGAAPPAPGPPARRDV 684
Query: 693 MPETIFQIRRTVPLWENIDVQDFIHRRLKENDADPSAPPYDSLATYAYEGNDSIADSLSS 752
+P ++ R DV + RL+E D DP PPYDS+ Y YEG S SLSS
Sbjct: 685 LPRA--RVSRQPRPPGPADVAQLLALRLREADEDPGVPPYDSVQVYGYEGRGSSCGSLSS 742
Query: 753 L--ESLTADCNQDYDYLSDWGPRFKKLADMYGGDD 785
L S + L DWGP F+ LA++YG +
Sbjct: 743 LGSGSEAGGAPGPAEPLDDWGPLFRTLAELYGAKE 777
>gi|32880206 cadherin-like 24 isoform 1 [Homo sapiens]
Length = 819
Score = 726 bits (1873), Expect = 0.0
Identities = 375/793 (47%), Positives = 525/793 (66%), Gaps = 51/793 (6%)
Query: 38 AGLTKDDGKMLRRTKRGWMWNQFFLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILTGDGA 97
AG + G L RT+R W+WNQFF++EEY G + +GKLH+D D+G+G KY+LTG+GA
Sbjct: 29 AGSREHPGPALLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGA 88
Query: 98 GSLFVIDENTGDIHAAKKLDREEKSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEP 157
G++FVIDE TG+IH K LDREEK+ Y+L A+A+DR + R +EP SEFIIK+ DINDN P
Sbjct: 89 GTVFVIDEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPP 148
Query: 158 KFTKDLYTASVPEMSGVGTSVIQVTATDADDANYGNSAKVVYSILQGQPYFSVDPESGII 217
F Y A+VPEMS VGTSVIQVTA DADD +YGNSAK+VY++L G P+FSVDP++G++
Sbjct: 149 IFPLGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLPFFSVDPQTGVV 208
Query: 218 KTALPDMSRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNNNPPRFPQSTYQFNS 277
+TA+P+M RE +E++ VVIQAKDMGG MGGLSG+TTV +TL+DVN+NPP+FPQS YQF+
Sbjct: 209 RTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSV 268
Query: 278 PESVPLGTHLGRIKANDPDVGENAEMEYSIAEGDGADMFDVITDKDTQEGIITVKQNLDF 337
E+ GT +GR++A DPD+G+NA M YSI +G+G++ F + TD ++G++TV++ LDF
Sbjct: 269 VETAGPGTLVGRLRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDF 328
Query: 338 ENQMLYTLRVDASNTHPDPRFLHLGPFKDTAVVKISVEDIDEPPVFTKVSYLIEVDEDVK 397
E+Q Y+ RV+A+NT DP +L GPFKD A V+++V+D EPP FT+ +Y + V E+
Sbjct: 329 ESQRSYSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVPENKA 388
Query: 398 EGSIIGQVTAYDPDARNNLIKYSVDRHTDMDRIFGIHSENGSIFTLKALDRESSPWHNIT 457
G+++GQ++A D D+ + I+YS+ H+D +R F I E G+I T LDRE+ WHN+T
Sbjct: 389 PGTLVGQISAADLDSPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLT 448
Query: 458 VTATEI--------------------------------------NNPKQSSHIPVFIRIL 479
V ATE+ ++ Q+S + V I+ L
Sbjct: 449 VLATELGWSWGPERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQASRVQVAIQTL 508
Query: 480 DINDHAPEFAMYYETFVCENAKPGQLIQTVSVMDKDDPPR-GHKFFFEPVPEFTLNPNFT 538
D ND+AP+ A Y+TFVC++A PGQLIQ + +D+D+ H F P+ + NFT
Sbjct: 509 DENDNAPQLAEPYDTFVCDSAAPGQLIQVIRALDRDEVGNSSHVSFQGPLGP---DANFT 565
Query: 539 IVDNKDNTAGIMTRKDGYSRNKMSTYLLPILIFDNDYPIQSSTGTLTIRVCACDNQGNMQ 598
+ DN+D +A ++ + + + YL+PI ++D P SST T+T+ VC C G++
Sbjct: 566 VQDNRDGSASLLL-PSRPAPPRHAPYLVPIELWDWGQPALSSTATVTVSVCRCQPDGSVA 624
Query: 599 SCTAEALILSAGLSTGALVAILLCVLILLILVVLFAALKRQRKKEPLIISKDDVRDNIVT 658
SC EA + +AGLSTGAL+AI+ CV LL LVVLF AL+RQ+++ +++ ++DVR+NI+T
Sbjct: 625 SCWPEAHLSAAGLSTGALLAIITCVGALLALVVLFVALRRQKQEALMVLEEEDVRENIIT 684
Query: 659 YNDEGGGEEDTQAFDIGTLRNPEA----REDSKLRRDVMPETIFQIRRTVPLWENIDVQD 714
Y+DEGGGEEDT+AFDI L+NP+ RRDV+P ++ R DV
Sbjct: 685 YDDEGGGEEDTEAFDITALQNPDGAAPPAPGPPARRDVLPRA--RVSRQPRPPGPADVAQ 742
Query: 715 FIHRRLKENDADPSAPPYDSLATYAYEGNDSIADSLSSL--ESLTADCNQDYDYLSDWGP 772
+ RL+E D DP PPYDS+ Y YEG S SLSSL S + L DWGP
Sbjct: 743 LLALRLREADEDPGVPPYDSVQVYGYEGRGSSCGSLSSLGSGSEAGGAPGPAEPLDDWGP 802
Query: 773 RFKKLADMYGGDD 785
F+ LA++YG +
Sbjct: 803 LFRTLAELYGAKE 815
>gi|12656655 cadherin 19, type 2 preproprotein [Homo sapiens]
Length = 772
Score = 716 bits (1848), Expect = 0.0
Identities = 366/734 (49%), Positives = 509/734 (69%), Gaps = 9/734 (1%)
Query: 50 RTKRGWMWNQFFLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILTGDGAGSLFVIDENTGD 109
R KRGW+WNQFF+ EE T + ++G+L +D D G+ + +Y L G GAGS F+IDE TGD
Sbjct: 40 RVKRGWVWNQFFVPEEMN-TTSHHIGQLRSDLDNGNNSFQYKLLGAGAGSTFIIDERTGD 98
Query: 110 IHAAKKLDREEKSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTKDLYTASVP 169
I+A +KLDREE+SLYILRA+ ID TGR VEPESEF+IK+ DINDNEPKF + Y A VP
Sbjct: 99 IYAIQKLDREERSLYILRAQVIDIATGRAVEPESEFVIKVSDINDNEPKFLDEPYEAIVP 158
Query: 170 EMSGVGTSVIQVTATDADDANYGNSAKVVYSILQGQPYFSVDPESGIIKTALPDMSRENR 229
EMS GT VIQVTA+DADD + GN+A+++YS+LQGQPYFSV+P +G+I+ + M RE +
Sbjct: 159 EMSPEGTLVIQVTASDADDPSSGNNARLLYSLLQGQPYFSVEPTTGVIRIS-SKMDRELQ 217
Query: 230 EQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNNNPPRFPQSTYQFNSPESVPLGTHLGR 289
++Y V+IQAKDM GQ G LSGTT+V I L+DVN+N P F +S Y+ ES P GT +G
Sbjct: 218 DEYWVIIQAKDMIGQPGALSGTTSVLIKLSDVNDNKPIFKESLYRLTVSESAPTGTSIGT 277
Query: 290 IKANDPDVGENAEMEYSIAEGDGADMFDVITDKDTQEGIITVKQNLDFENQMLYTLRVDA 349
I A D D+GENAEM+YSI E D + FD+IT+ +TQEGI+ +K+ +DFE+Q Y +R
Sbjct: 278 IMAYDNDIGENAEMDYSIEEDD-SQTFDIITNHETQEGIVILKKKVDFEHQNHYGIRAKV 336
Query: 350 SNTHPDPRFLHLGPFKDTAVVKISVEDIDEPPVFTKVSYLIEVDEDVKEGSIIGQVTAYD 409
N H + + T +KI VED+DEPP+F Y+ EV E+ +GS +G V+A D
Sbjct: 337 KNHHVPEQLMKYHTEASTTFIKIQVEDVDEPPLFLLPYYVFEVFEETPQGSFVGVVSATD 396
Query: 410 PDARNNLIKYSVDRHTDMDRIFGIHSENGSIFTLKALDRESSPWHNITVTATEINNPKQS 469
PD R + I+YS+ R ++F I+ +NG+I T +LDRE S W+N+++TATE N +Q
Sbjct: 397 PDNRKSPIRYSITR----SKVFNIN-DNGTITTSNSLDREISAWYNLSITATEKYNIEQI 451
Query: 470 SHIPVFIRILDINDHAPEFAMYYETFVCENAKPGQLIQTVSVMDKDDPPRGHKFFFEPVP 529
S IP+++++L+INDHAPEF+ YYET+VCENA GQ+IQT+S +D+D+ H F+F
Sbjct: 452 SSIPLYVQVLNINDHAPEFSQYYETYVCENAGSGQVIQTISAVDRDESIEEHHFYFNLSV 511
Query: 530 EFTLNPNFTIVDNKDNTAGIMTRKDGYSRNKMSTYLLPILIFDNDYPIQSSTGTLTIRVC 589
E T N +FTI+DN+DNTA I+T + G++ + + + ILI DN P +ST TLTI VC
Sbjct: 512 EDTNNSSFTIIDNQDNTAVILTNRTGFNLQEEPVFYISILIADNGIPSLTSTNTLTIHVC 571
Query: 590 ACDNQGNMQSCTAEALILSAGLSTGALVAILLCVLILLILVVLFAALKRQRKKEPLIISK 649
C + G+ Q+C + L+LS G T ++AIL+C++I+ + L LK++RK+
Sbjct: 572 DCGDSGSTQTCQYQELVLSMGFKTEVIIAILICIMIIFGFIFLTLGLKQRRKQILFPEKS 631
Query: 650 DDVRDNIVTYNDEGGGEEDTQAFDIGTLRNPEAREDSKLRRDVMPETIFQIRRTVPLWEN 709
+D R+NI Y+DEGGGEEDT+AFDI LR+ + K R+ E R+++ + +
Sbjct: 632 EDFRENIFQYDDEGGGEEDTEAFDIAELRSSTIMRERKTRKTTSAEIRSLYRQSLQVGPD 691
Query: 710 IDV-QDFIHRRLKENDADPSAPPYDSLATYAYEGNDSIADSLSSLESLTADCNQDYDYLS 768
+ + FI +L+E + DP APP+DSL TYA+EG S+A SLSSLES +D ++ YDYL+
Sbjct: 692 SAIFRKFILEKLEEANTDPCAPPFDSLQTYAFEGTGSLAGSLSSLESAVSDQDESYDYLN 751
Query: 769 DWGPRFKKLADMYG 782
+ GPRFK+LA M+G
Sbjct: 752 ELGPRFKRLACMFG 765
>gi|166362713 cadherin 5, type 2 preproprotein [Homo sapiens]
Length = 784
Score = 531 bits (1369), Expect = e-151
Identities = 308/751 (41%), Positives = 443/751 (58%), Gaps = 31/751 (4%)
Query: 49 RRTKRGWMWNQFFLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILTGDGAGSLFVIDENTG 108
RR KR W+WNQ + EE + +VGK+ + + N KY+L G+ G +F +D TG
Sbjct: 43 RRQKRDWIWNQMHIDEEKNTSLPHHVGKIKSSVSRK--NAKYLLKGEYVGKVFRVDAETG 100
Query: 109 DIHAAKKLDREEKSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTKDLYTASV 168
D+ A ++LDRE S Y L A +D+ TG +E S F IK+HD+NDN P FT L+ ASV
Sbjct: 101 DVFAIERLDRENISEYHLTAVIVDKDTGENLETPSSFTIKVHDVNDNWPVFTHRLFNASV 160
Query: 169 PEMSGVGTSVIQVTATDADDANYGNSAKVVYSILQGQPYFSVDPESGIIKTALPDMSREN 228
PE S VGTSVI VTA DADD G+ A V+Y IL+G+ YF++D SG I T + RE
Sbjct: 161 PESSAVGTSVISVTAVDADDPTVGDHASVMYQILKGKEYFAID-NSGRIITITKSLDREK 219
Query: 229 REQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNNNPPRFPQSTYQFNSPESVPLGTHLG 288
+ +Y++V++A+D G + G SGT TV +TL D+N+N P F Q+ Y F PE +GT +G
Sbjct: 220 QARYEIVVEARDAQG-LRGDSGTATVLVTLQDINDNFPFFTQTKYTFVVPEDTRVGTSVG 278
Query: 289 RIKANDPDVGENAEMEYSIAEGDGADMFDVITDKDTQEGIITVKQNLDFENQMLYTLRVD 348
+ DPD +N +YSI GD D F + T+ EGII + LD+E Y+ V+
Sbjct: 279 SLFVEDPDEPQNRMTKYSILRGDYQDAFTIETNPAHNEGIIKPMKPLDYEYIQQYSFIVE 338
Query: 349 ASNTHPDPRFLHLGPFKDTAVVKISVEDIDEPPVFTKVSYLIEVDEDVKEGSIIGQVTAY 408
A++ D R++ P + A V I++ D+DEPP+F + Y ++ E+ K+ +IG V A
Sbjct: 339 ATDPTIDLRYMS-PPAGNRAQVIINITDVDEPPIFQQPFYHFQLKENQKK-PLIGTVLAM 396
Query: 409 DPDARNNLIKYSVDRHTDMDRIFGIHSENGSIFTLKALDRESSPWHNITVTATEINN--- 465
DPDA + I YS+ R +D + F + ++ G I+ K LDRE PW+N+TV A E+++
Sbjct: 397 DPDAARHSIGYSIRRTSDKGQFFRV-TKKGDIYNEKELDREVYPWYNLTVEAKELDSTGT 455
Query: 466 -PKQSSHIPVFIRILDINDHAPEFAMYYETFVCENAKPGQLIQTVSVMDKDDPPRGHKFF 524
+ S + V I +LD ND+APEFA Y+ VCENA GQL+ +S +DKD PR KF
Sbjct: 456 PTGKESIVQVHIEVLDENDNAPEFAKPYQPKVCENAVHGQLVLQISAIDKDITPRNVKF- 514
Query: 525 FEPVPEFTLNP--NFTIVDNKDNTAGIMTRKDGYSRNKMSTYLLPILIFDNDYPIQSSTG 582
+F LN NFT+ DN DNTA I + + R + LP++I DN P ++ T
Sbjct: 515 -----KFILNTENNFTLTDNHDNTANITVKYGQFDREHTKVHFLPVVISDNGMPSRTGTS 569
Query: 583 TLTIRVCACDNQGNMQSCTAEALILSAGLSTGALVAILLCVLILLILVVLFAALKRQRKK 642
TLT+ VC C+ QG C E + G+S A+VAILLC+L + ++ +L +R RK+
Sbjct: 570 TLTVAVCKCNEQGEFTFC--EDMAAQVGVSIQAVVAILLCILTITVITLLIFLRRRLRKQ 627
Query: 643 EPLI-ISKDDVRDNIVTYNDEGGGEEDTQAFDIGTLRNPEAREDSKLRR---DVMPETIF 698
S ++ + +VTY++EGGGE DT ++D+ L N R +K R D P
Sbjct: 628 ARAHGKSVPEIHEQLVTYDEEGGGEMDTTSYDVSVL-NSVRRGGAKPPRPALDARPSLYA 686
Query: 699 QIRRTVPLWENI-----DVQDFIHRRLKENDADPSAPPYDSLATYAYEGNDSIADSLSSL 753
Q+++ ++ I + E D D PPYD+L Y YEG++SIA+SLSSL
Sbjct: 687 QVQKPPRHAPGAHGGPGEMAAMIEVKKDEADHDGDGPPYDTLHIYGYEGSESIAESLSSL 746
Query: 754 ESLTADCNQDYDYLSDWGPRFKKLADMYGGD 784
+ ++D + DYD+L+DWGPRFK LA++YG D
Sbjct: 747 GTDSSDSDVDYDFLNDWGPRFKMLAELYGSD 777
>gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens]
Length = 906
Score = 423 bits (1088), Expect = e-118
Identities = 284/771 (36%), Positives = 419/771 (54%), Gaps = 52/771 (6%)
Query: 48 LRRTKRGWMWNQFFLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILTGDGAGS----LFVI 103
L+R KR W+ L E G Q + ++ +D+DK + +L+Y +TG GA +F+I
Sbjct: 154 LQRQKRDWVIPPINLPENSRGPFPQELVRIRSDRDK-NLSLRYSVTGPGADQPPTGIFII 212
Query: 104 DENTGDIHAAKKLDREEKSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTKDL 163
+ +G + K LDRE+ + + LRA A+D G QVE + +I + D+NDN P+F +
Sbjct: 213 NPISGQLSVTKPLDREQIARFHLRAHAVDIN-GNQVENPIDIVINVIDMNDNRPEFLHQV 271
Query: 164 YTASVPEMSGVGTSVIQVTATDADDANYGNSAKVVYSILQGQP------YFSVDPESGII 217
+ +VPE S GT V+ VTA DADD N N + Y I+ P F+++ E+G I
Sbjct: 272 WNGTVPEGSKPGTYVMTVTAIDADDPNALNGM-LRYRIVSQAPSTPSPNMFTINNETGDI 330
Query: 218 KTALPDMSRENREQYQVVIQAKDM-GGQMGGLSGTTTVNITLTDVNNNPPRFPQSTYQFN 276
T + RE +QY ++IQA DM G GLS T T IT+TDVN+NPP F T+
Sbjct: 331 ITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGE 390
Query: 277 SPESVPLGTHLGRIKANDPDVGENAEME--YSIAEGDGADMFDVITDKDTQEGIITVKQN 334
PE+ + + + D D Y I+ GD F + TD ++ +G++TV +
Sbjct: 391 VPEN-RVDIIVANLTVTDKDQPHTPAWNAVYRISGGDPTGRFAIQTDPNSNDGLVTVVKP 449
Query: 335 LDFENQMLYTLRVDASNTHPDPRFLHLGPFKDTAVVKISVEDIDEPPVFTKVSYLIEVDE 394
+DFE ++ L V A N P + + P + TA V ++V D++E P F +I +E
Sbjct: 450 IDFETNRMFVLTVAAENQVPLAKGIQHPP-QSTATVSVTVIDVNENPYFAPNPKIIRQEE 508
Query: 395 DVKEGSIIGQVTAYDPDA-RNNLIKYSVDRHTDMDRIFGIHSENGSIFTLKALDRES--- 450
+ G+++ TA DPD I+Y+ + +D I NG I T+ LDRES
Sbjct: 509 GLHAGTMLTTFTAQDPDRYMQQNIRYT--KLSDPANWLKIDPVNGQITTIAVLDRESPNV 566
Query: 451 -SPWHNITVTATEINNPKQSSHIPVFIRILDINDHAPEFAMYYETFVCENAKPGQLIQTV 509
+ +N T A++ P S + I +LDIND+AP+ + E CE P + +
Sbjct: 567 KNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQ-VLPQEAETCETPDPNSI--NI 623
Query: 510 SVMDKDDPPRGHKFFFE-PVPEFTLNPNFTIVDNKDNTAGIMTRKDGYSRNKMSTYLLPI 568
+ +D D P F F+ P+ T+ N+TI + A + + + Y +PI
Sbjct: 624 TALDYDIDPNAGPFAFDLPLSPVTIKRNWTITRLNGDFAQLNLK---IKFLEAGIYEVPI 680
Query: 569 LIFDNDYPIQSSTGTLTIRVCACDNQGNMQSCTAEALILSAGLSTGALVAILLCVLILLI 628
+I D+ P +S+ L ++VC CD+ G+ CT I+ AGL TGA++AILLC++ILLI
Sbjct: 681 IITDSGNPPKSNISILRVKVCQCDSNGD---CTDVDRIVGAGLGTGAIIAILLCIIILLI 737
Query: 629 LVVLFAALKRQRKKEP-----LIISKDDVRDNIVTYNDEGGGEEDTQAFDIGTLRNPEAR 683
LV++F ++R KE LI +DDVRDNI+ Y++EGGGEED Q +D+ L+ P+
Sbjct: 738 LVLMFVVWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGEED-QDYDLSQLQQPDTV 796
Query: 684 EDSKLR---------RDVMPETIFQIRRTVPLWENIDVQDFIHRRLKENDADPSAPPYDS 734
E ++ R + E + +R P D+ DFI+ LK D DP+APPYDS
Sbjct: 797 EPDAIKPVGIRRMDERPIHAEPQYPVRSAAP--HPGDIGDFINEGLKAADNDPTAPPYDS 854
Query: 735 LATYAYEGNDSIADSLSSLESLTADCNQDYDYLSDWGPRFKKLADMYGGDD 785
L + YEG+ S A SLSSL S ++ QDYDYL+DWGPRFKKLADMYGG D
Sbjct: 855 LLVFDYEGSGSTAGSLSSLNSSSSGGEQDYDYLNDWGPRFKKLADMYGGGD 905
>gi|14589893 cadherin 4, type 1 preproprotein [Homo sapiens]
Length = 916
Score = 421 bits (1081), Expect = e-117
Identities = 295/773 (38%), Positives = 417/773 (53%), Gaps = 53/773 (6%)
Query: 48 LRRTKRGWMWNQFFLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILTGDGAGS----LFVI 103
LRR KR W+ + E G Q + ++ +D+D D ++Y +TG GA +F I
Sbjct: 164 LRRRKRDWVIPPINVPENSRGPFPQQLVRIRSDKDN-DIPIRYSITGVGADQPPMEVFSI 222
Query: 104 DENTGDIHAAKKLDREEKSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTKDL 163
D +G ++ + +DREE + Y LRA A+D G +VE + I + D+NDN P+F +
Sbjct: 223 DSMSGRMYVTRPMDREEHASYHLRAHAVDMN-GNKVENPIDLYIYVIDMNDNRPEFINQV 281
Query: 164 YTASVPEMSGVGTSVIQVTATDADDANYGNSAKVVYSILQGQPY------FSVDPESGII 217
Y SV E S GT V+ VTA DADD+ N V Y I+ P F+++ E+G I
Sbjct: 282 YNGSVDEGSKPGTYVMTVTANDADDSTTANGM-VRYRIVTQTPQSPSQNMFTINSETGDI 340
Query: 218 KTALPDMSRENREQYQVVIQAKDMGGQMG-GLSGTTTVNITLTDVNNNPPRFPQSTYQFN 276
T + RE +QY V++QA DM G + GLS T T IT+TDVN+NPP F ST+
Sbjct: 341 VTVAAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGE 400
Query: 277 SPESVPLGTHLGRIKANDPDV--GENAEMEYSIAEGDGADMFDVITDKDTQEGIITVKQN 334
PE+ + T + + D D N Y I GD + F V TD T EG++TV +
Sbjct: 401 VPEN-RVETVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKA 459
Query: 335 LDFENQMLYTLRVDASNTHPDPRFLHLGPFKDTAVVKISVEDIDEPPVFTKVSYLIEVDE 394
+D+E + L V SN P + + F+ TA V IS+ DI+E P F LI ++E
Sbjct: 460 VDYELNRAFMLTVMVSNQAPLASGIQMS-FQSTAGVTISIMDINEAPYFPSNHKLIRLEE 518
Query: 395 DVKEGSIIGQVTAYDPDA-RNNLIKYSVDRHTDMDRIFGIHSENGSIFTLKALDRESSPW 453
V G+++ +A DPD ++YS + +D I++ NG I T LDRES
Sbjct: 519 GVPPGTVLTTFSAVDPDRFMQQAVRYS--KLSDPASWLHINATNGQITTAAVLDRESLYT 576
Query: 454 HN----ITVTATEINNPKQSSHIPVFIRILDINDHAPEFAMYYETFVCENAKPGQLIQTV 509
N T A + P S + I ++DIND+APE + E +CE KP +
Sbjct: 577 KNNVYEATFLAADNGIPPASGTGTLQIYLIDINDNAPEL-LPKEAQICE--KPNLNAINI 633
Query: 510 SVMDKDDPPRGHKFFFE-PVPEFTLNPNFTIVDNKDNTAGIMTRKDGYSRNKMSTYLLPI 568
+ D D P + FE P + N+TI + A + R + Y +PI
Sbjct: 634 TAADADVDPNIGPYVFELPFVPAAVRKNWTITRLNGDYAQLSLR---ILYLEAGMYDVPI 690
Query: 569 LIFDNDYPIQSSTGTLTIRVCACDNQGNMQSCTAEALILSAGLSTGALVAILLCVLILLI 628
++ D+ P S+T + ++VC CD+ G+ CT + +AGL TGA+VAIL+C+LILL
Sbjct: 691 IVTDSGNPPLSNTSIIKVKVCPCDDNGD---CTTIGAVAAAGLGTGAIVAILICILILLT 747
Query: 629 LVVLFAALKRQRKKEP-----LIISKDDVRDNIVTYNDEGGGEEDTQAFDIGTLRNPEA- 682
+V+LF ++R+KE LI +DDVRDNI+ Y++EGGGEED Q +D+ L+ PEA
Sbjct: 748 MVLLFVMWMKRREKERHTKQLLIDPEDDVRDNILKYDEEGGGEED-QDYDLSQLQQPEAM 806
Query: 683 -REDSKL-------RRDVMPETIFQIRRTVPLWENIDVQDFIHRRLKENDADPSAPPYDS 734
SK R V E + IR VP D+ DFI+ L+ D DP+APPYDS
Sbjct: 807 GHVPSKAPGVRRVDERPVGAEPQYPIRPMVP--HPGDIGDFINEGLRAADNDPTAPPYDS 864
Query: 735 LATYAYEGNDSIADSLSSLESLTADCNQDYDYLSDWGPRFKKLADMYGGDDSD 787
L + YEG+ S A S+SSL S ++ +QDYDYL+DWGPRFKKLADMYGG + D
Sbjct: 865 LLVFDYEGSGSTAGSVSSLNSSSSG-DQDYDYLNDWGPRFKKLADMYGGGEED 916
>gi|4757960 cadherin 1, type 1 preproprotein [Homo sapiens]
Length = 882
Score = 371 bits (953), Expect = e-102
Identities = 267/762 (35%), Positives = 391/762 (51%), Gaps = 50/762 (6%)
Query: 48 LRRTKRGWMWNQFFLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILTGDGAGS----LFVI 103
LRR KR W+ E G + + ++ +++DK +G + Y +TG GA + +F+I
Sbjct: 149 LRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDK-EGKVFYSITGQGADTPPVGVFII 207
Query: 104 DENTGDIHAAKKLDREEKSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTKDL 163
+ TG + + LDRE + Y L + A+ G VE E +I + D NDN+P+FT+++
Sbjct: 208 ERETGWLKVTEPLDRERIATYTLFSHAVS-SNGNAVEDPMEILITVTDQNDNKPEFTQEV 266
Query: 164 YTASVPEMSGVGTSVIQVTATDADDANYGNSAKVVYSILQGQP------YFSVDPESGII 217
+ SV E + GTSV++VTATDADD +A + Y+IL P F+++ +G+I
Sbjct: 267 FKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVI 326
Query: 218 KTALPDMSRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNNNPPRFPQSTYQFNS 277
+ RE+ Y +V+QA D+ G+ GLS T T IT+TD N+NPP F +TY+
Sbjct: 327 SVVTTGLDRESFPTYTLVVQAADLQGE--GLSTTATAVITVTDTNDNPPIFNPTTYKGQV 384
Query: 278 PESVPLGTHLGRIKANDPDVGENAEME--YSIAEGDGADMFDVITDKDTQEGIITVKQNL 335
PE+ + +K D D E Y+I DG F V T+ +GI+ + L
Sbjct: 385 PEN-EANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQ-FVVTTNPVNNDGILKTAKGL 442
Query: 336 DFENQMLYTLRVDASNTHPDPRFLHLGPFKDTAVVKISVEDIDEPPVFTKVSYLIEVDED 395
DFE + Y L V +N P + TA V + V D++E P+F +EV ED
Sbjct: 443 DFEAKQQYILHVAVTNVVP----FEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSED 498
Query: 396 VKEGSIIGQVTAYDPDA-RNNLIKYSVDRHTDMDRIFGIHSENGSIFTLKALDRES---- 450
G I TA +PD I Y + R D I+ + G+I T LDRE
Sbjct: 499 FGVGQEITSYTAQEPDTFMEQKITYRIWR--DTANWLEINPDTGAISTRAELDREDFEHV 556
Query: 451 -SPWHNITVTATEINNPKQSSHIPVFIRILDINDHAPEFAMYYETFVCE-NAKPGQLIQT 508
+ + + AT+ +P + + + + D+ND+AP F CE N KP Q
Sbjct: 557 KNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAP-IPEPRTIFFCERNPKP----QV 611
Query: 509 VSVMDKDDPPRGHKFFFEPVPEFTLNPNFTIVDNKDNTAGIMTRKDGYSRNKMSTYLLPI 568
++++D D PP F E + N+TI N I+ + ++ Y + +
Sbjct: 612 INIIDADLPPNTSPFTAELT--HGASANWTIQYNDPTQESIILKPK--MALEVGDYKINL 667
Query: 569 LIFDNDYPIQSSTGTLTIRVCACDNQGNMQSCTAEALILSAGLSTGALVAILLCVLILLI 628
+ DN Q+ T+ V CD +G C +A + AGL A++ IL +L LLI
Sbjct: 668 KLMDN----QNKDQVTTLEVSVCDCEGAAGVCR-KAQPVEAGLQIPAILGILGGILALLI 722
Query: 629 LVVLFAALKRQRK--KEPLIISKDDVRDNIVTYNDEGGGEEDTQAFDIGTLRNPEAREDS 686
L++L R+R KEPL+ +DD RDN+ Y++EGGGEED Q FD+ L
Sbjct: 723 LILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEED-QDFDLSQLHRGLDARPE 781
Query: 687 KLRRDVMPETIFQIRRTVPLWENID-VQDFIHRRLKENDADPSAPPYDSLATYAYEGNDS 745
R DV P T+ + R +P N D + +FI LK D DP+APPYDSL + YEG+ S
Sbjct: 782 VTRNDVAP-TLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGS 840
Query: 746 IADSLSSLESLTADCNQDYDYLSDWGPRFKKLADMYGGDDSD 787
A SLSSL S +D +QDYDYL++WG RFKKLADMYGG + D
Sbjct: 841 EAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD 882
>gi|14589891 cadherin 3, type 1 preproprotein [Homo sapiens]
Length = 829
Score = 360 bits (925), Expect = 2e-99
Identities = 263/764 (34%), Positives = 396/764 (51%), Gaps = 56/764 (7%)
Query: 46 KMLRRTKRGWMWNQFFLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILTGDGAGS----LF 101
++LRR KR W+ + E G Q + +L +++D+ D + Y +TG GA S +F
Sbjct: 100 RILRRHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDR-DTKIFYSITGPGADSPPEGVF 158
Query: 102 VIDENTGDIHAAKKLDREEKSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTK 161
+++ TG + K LDREE + Y L A+ + G VE I + D ND++PKFT+
Sbjct: 159 AVEKETGWLLLNKPLDREEIAKYELFGHAVS-ENGASVEDPMNISIIVTDQNDHKPKFTQ 217
Query: 162 DLYTASVPEMSGVGTSVIQVTATDADDANYGNSAKVVYSILQGQP------YFSVDPESG 215
D + SV E GTSV+QVTATD DDA Y + V YSI +P F++ +G
Sbjct: 218 DTFRGSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRSTG 277
Query: 216 IIKTALPDMSRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNNNPPRFPQSTYQF 275
I + RE +Y + IQA DM G G + T + + D N+N P F Y+
Sbjct: 278 TISVISSGLDREKVPEYTLTIQATDMDGD--GSTTTAVAVVEILDANDNAPMFDPQKYEA 335
Query: 276 NSPESVPLGTHLGRIKANDPDVGENAEME--YSIAEGDGADMFDVITDKDTQEGIITVKQ 333
+ PE+ +G + R+ D D + Y I GD D F + T ++ +GI+T ++
Sbjct: 336 HVPENA-VGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHPESNQGILTTRK 394
Query: 334 NLDFENQMLYTLRVDASNTHPDPRFLHLGPFKDTAVVKISVEDIDEPPVFTKVSYLIEVD 393
LDFE + +TL V+ +N P F+ P TA + + VED++E PVF S ++EV
Sbjct: 395 GLDFEAKNQHTLYVEVTNEAP---FVLKLP-TSTATIVVHVEDVNEAPVFVPPSKVVEVQ 450
Query: 394 EDVKEGSIIGQVTAYDPDARNNLIKYSVDRHTDMDRIFGIHSENGSIFTLKALDRESSPW 453
E + G + TA DPD N I Y + R D + ++G + + LDRE +
Sbjct: 451 EGIPTGEPVCVYTAEDPDKENQKISYRILR--DPAGWLAMDPDSGQVTAVGTLDREDEQF 508
Query: 454 -----HNITVTATEINNPKQSSHIPVFIRILDINDHAPEFAMYYETFVCENAKPGQLIQT 508
+ + V A + +P + + + ++D+NDH P T +C N P + Q
Sbjct: 509 VRNNIYEVMVLAMDNGSPPTTGTGTLLLTLIDVNDHGPVPEPRQIT-IC-NQSPVR--QV 564
Query: 509 VSVMDKDDPPRGHKFFFEPVPEFTLNPNFTIVDNKDNTAGIMTRKDGYSRNKMSTYLLPI 568
+++ DKD P F + + + +T N++ +++ K K TY + +
Sbjct: 565 LNITDKDLSPHTSPFQAQLTDDSDIY--WTAEVNEEGDTVVLSLKKFL---KQDTYDVHL 619
Query: 569 LIFDNDYPIQSSTGTLTIRVCACDNQGNMQSCTAE---ALILSAGLSTGALVAILLCVLI 625
+ D+ Q + IR CD G++++C IL GA++A+L +L+
Sbjct: 620 SLSDHGNKEQLTV----IRATVCDCHGHVETCPGPWKGGFILPV---LGAVLALLFLLLV 672
Query: 626 LLILVVLFAALKRQRKKEPLIISKDDVRDNIVTYNDEGGGEEDTQAFDIGTL-RNPEARE 684
LL+LV K+++ KEPL++ +DD RDN+ Y +EGGGEED Q +DI L R EAR
Sbjct: 673 LLLLV-----RKKRKIKEPLLLPEDDTRDNVFYYGEEGGGEED-QDYDITQLHRGLEARP 726
Query: 685 DSKLRRDVMPETIFQIRRTVPLWENID-VQDFIHRRLKENDADPSAPPYDSLATYAYEGN 743
+ LR DV P TI P N D + +FI LK + DP+APPYD+L + YEG+
Sbjct: 727 EVVLRNDVAP-TIIPTPMYRPRPANPDEIGNFIIENLKAANTDPTAPPYDTLLVFDYEGS 785
Query: 744 DSIADSLSSLESLTADCNQDYDYLSDWGPRFKKLADMYGGDDSD 787
S A SLSSL S +D +QDYDYL++WG RFKKLADMYGG + D
Sbjct: 786 GSDAASLSSLTSSASDQDQDYDYLNEWGSRFKKLADMYGGGEDD 829
>gi|4826669 cadherin 15 preproprotein [Homo sapiens]
Length = 814
Score = 344 bits (882), Expect = 2e-94
Identities = 250/756 (33%), Positives = 378/756 (50%), Gaps = 35/756 (4%)
Query: 48 LRRTKRGWMWNQFFLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILTGDGAGS----LFVI 103
L R +R W+ + E + V ++ +D+ + G++ Y + G G +F I
Sbjct: 40 LSRVRRAWVIPPISVSENHKRLPYPLV-QIKSDKQQL-GSVIYSIQGPGVDEEPRGVFSI 97
Query: 104 DENTGDIHAAKKLDREEKSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTKDL 163
D+ TG + LDRE+ + LRA A+D G +E ++ I + D NDN P F ++
Sbjct: 98 DKFTGKVFLNAMLDREKTDRFRLRAFALDLG-GSTLEDPTDLEIVVVDQNDNRPAFLQEA 156
Query: 164 YTASVPEMSGVGTSVIQVTATDADDANYGNSAKVVYSILQGQP-YFSVDPESGIIKTALP 222
+T V E + GT V + ATDADD N+A + QG P FS+D +G I+T
Sbjct: 157 FTGRVLEGAVPGTYVTRAEATDADDPETDNAALRFSILQQGSPELFSIDELTGEIRTVQV 216
Query: 223 DMSRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNNNPPRFPQSTYQFNSPESVP 282
+ RE Y + +Q DM G GL+ T + ITL D+N+N P F + + + E+V
Sbjct: 217 GLDREVVAVYNLTLQVADMSGD--GLTATASAIITLDDINDNAPEFTRDEFFMEAIEAVS 274
Query: 283 LGTHLGRIKANDPDV--GENAEMEYSIAEGDGADMFDVITDKDTQEGIITVKQNLDFENQ 340
G +GR++ D D+ N ++I EGD F + TD T EG++++ + LD+E+
Sbjct: 275 -GVDVGRLEVEDRDLPGSPNWVARFTILEGDPDGQFTIRTDPKTNEGVLSIVKALDYESC 333
Query: 341 MLYTLRVDASNTHPDPRFLHLGPFKDTAVVKISVEDIDEPPVFTKVSYLIEVDEDVKEGS 400
Y L+V N P + L + A V++ V+D +EPPVF + + E G+
Sbjct: 334 EHYELKVSVQNEAP-LQAAALRAERGQAKVRVHVQDTNEPPVFQENPLRTSLAEGAPPGT 392
Query: 401 IIGQVTAYDPDARNNLIKYSVDRHTDMDRIFGIHSENGSIFTLKALDRES----SPWHNI 456
++ +A DPD L + S + D + + + G I T L S W+
Sbjct: 393 LVATFSARDPDTEQ-LQRLSYSKDYDPEDWLQVDAATGRIQTQHVLSPASPFLKGGWYRA 451
Query: 457 TVTATEINNPKQSSHIPVFIRILDINDHAPEFAMYYETFVCENAKPGQLIQTVSVMDKDD 516
V A + + +++ + I IL++NDHAP A +C G + + D+D
Sbjct: 452 IVLAQDDASQPRTATGTLSIEILEVNDHAPVLAPPPPGSLCSEPHQGPGL-LLGATDEDL 510
Query: 517 PPRGHKFFFEPVPEFT-LNPNFTIVDNKDNTAGIMTRKDGYSRNKMSTYLLPILIFDNDY 575
PP G F F+ P L N+++ + A + R + + L +L+ D+
Sbjct: 511 PPHGAPFHFQLSPRLPELGRNWSLSQVNVSHARLRPRH----QVPEGLHRLSLLLRDSGQ 566
Query: 576 PIQSSTGTLTIRVCACDNQGNMQSCTAEALILSAGLSTGALVAILLCVLILLILVVLFAA 635
P Q L + VC C G A L GLS GALV +L L+LL+LV+L A
Sbjct: 567 PPQQREQPLNVTVCRCGKDGVCLPGAAALLAGGTGLSLGALVIVLASALLLLVLVLLVAL 626
Query: 636 L----KRQRKKEPLIISKDDVRDNIVTYNDEGGGEEDTQAFDIGTLRNPEARE----DSK 687
K+ R K L +DD+RDN++ Y+++GGGEED A+DI LR+P A
Sbjct: 627 RARFWKQSRGKGLLHGPQDDLRDNVLNYDEQGGGEEDQDAYDISQLRHPTALSLPLGPPP 686
Query: 688 LRRDVMPETIF-QIRRTVPLWENIDVQDFIHRRLKENDADPSAPPYDSLATYAYEGNDSI 746
LRRD + Q R +P +D+ DFI+ L+ D+DPS PPYD+ Y YEG+ S+
Sbjct: 687 LRRDAPQGRLHPQPPRVLPT-SPLDIADFINDGLEAADSDPSVPPYDTALIYDYEGDGSV 745
Query: 747 ADSLSSLESLTADCNQDYDYLSDWGPRFKKLADMYG 782
A +LSS+ S D +QDYDYL DWGPRF +LADMYG
Sbjct: 746 AGTLSSILSSQGDEDQDYDYLRDWGPRFARLADMYG 781
>gi|148539848 desmocollin 3 isoform Dsc3b preproprotein [Homo
sapiens]
Length = 839
Score = 229 bits (585), Expect = 6e-60
Identities = 193/668 (28%), Positives = 322/668 (48%), Gaps = 55/668 (8%)
Query: 21 TILLQEKPNSYLSSKKIAGLTKDDGKMLRRTKRGWMWNQFFLLEEYTGTDTQYVGKLHTD 80
T+LL+ + KK++ +LRR KR W + E G ++ ++ +D
Sbjct: 110 TVLLEHQ-------KKVSKTRHTRETVLRRAKRRWAPIPCSMQENSLGPFPLFLQQVESD 162
Query: 81 QDKGDGNLKYILTGDGAG----SLFVIDENTGDIHAAKKLDREEKSLYILRAKAIDRKTG 136
+ + + Y ++G G +LF I+ +TG++ + +DREE ++ L A A G
Sbjct: 163 AAQ-NYTVFYSISGRGVDKEPLNLFYIERDTGNLFCTRPVDREEYDVFDLIAYA-STADG 220
Query: 137 RQVEPESEFIIKIHDINDNEPKFTKDLYTASVPEMSGVGTSVIQVTATDADDANYGNSAK 196
+ I++ D NDN P FT+ +Y V E S GT+V V ATD D+ + ++ +
Sbjct: 221 YSADLPLPLPIRVEDENDNHPVFTEAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHT-R 279
Query: 197 VVYSILQGQP----YFSVDPESGIIKTALPDMSRENREQYQVVIQAKDMGGQMGGLSGTT 252
+ YSILQ P FSV P +G+I T + RE ++Y ++++ +DM GQ GL GT+
Sbjct: 280 LKYSILQQTPRSPGLFSVHPSTGVITTVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTS 339
Query: 253 TVNITLTDVNNNPPRFPQSTYQFNSPESVPLGTHLGRIKANDPDVGENAE--MEYSIAEG 310
T IT+TD N+N P F Q+ Y+ E+ + RI D D+ A + ++I +G
Sbjct: 340 TCIITVTDSNDNAPTFRQNAYEAFVEENA-FNVEILRIPIEDKDLINTANWRVNFTILKG 398
Query: 311 DGADMFDVITDKDTQEGIITVKQNLDFENQMLYTLRVDASNTHPDPRFLHLGPFKDTAVV 370
+ F + TDK+T EG+++V + L++E L + +N P R + + A+V
Sbjct: 399 NENGHFKISTDKETNEGVLSVVKPLNYEENRQVNLEIGVNNEAPFARDIPRVTALNRALV 458
Query: 371 KISVEDIDEPPVFTKVSYLIEVDEDVKEGSIIGQVTAYDPDARN-NLIKYSVDRHTDMDR 429
+ V D+DE P T + + + E++ GS I AYDP+ RN N ++Y + D
Sbjct: 459 TVHVRDLDEGPECTPAAQYVRIKENLAVGSKINGYKAYDPENRNGNGLRYK--KLHDPKG 516
Query: 430 IFGIHSENGSIFTLKALDRE----SSPWHNITVTATEINNPKQSSHIPVFIRILDINDHA 485
I +GSI T K LDRE + +NITV A I+ +S + + I D+ND+
Sbjct: 517 WITIDEISGSIITSKILDREVETPKNELYNITVLA--IDKDDRSCTGTLAVNIEDVNDNP 574
Query: 486 PEFAMYYETFVCENAKPGQLIQTVSVMDKDDPPRGHKFFFE-PVPEFTLNPNFTIVDNKD 544
PE Y +C KP + +D D+P G F+F P ++ +++ D
Sbjct: 575 PEILQEY-VVIC---KPKMGYTDILAVDPDEPVHGAPFYFSLPNTSPEISRLWSLTKVND 630
Query: 545 NTAGIMTRKDGYSRNKMSTYLLPILIFDNDYPIQSSTGTLTIRVCACDNQGNMQSCTAEA 604
A + +K+ Y +PI + D Q++T L + +C C + C A +
Sbjct: 631 TAARLSYQKNA----GFQEYTIPITV--KDRAGQAATKLLRVNLCECTHP---TQCRATS 681
Query: 605 LILSAGLSTGALVAILLCVLILLILVV-----LFAALKRQRKKEPLIISKDDVRDNIVTY 659
L A++AILL + +L +++ +F A K +R E L + N++
Sbjct: 682 RSTGVILGKWAILAILLGIALLFSVLLTLVCGVFGATKGKRFPEDL------AQQNLIIS 735
Query: 660 NDEGGGEE 667
N E G++
Sbjct: 736 NTEAPGDD 743
>gi|148539846 desmocollin 3 isoform Dsc3a preproprotein [Homo
sapiens]
Length = 896
Score = 229 bits (585), Expect = 6e-60
Identities = 193/668 (28%), Positives = 322/668 (48%), Gaps = 55/668 (8%)
Query: 21 TILLQEKPNSYLSSKKIAGLTKDDGKMLRRTKRGWMWNQFFLLEEYTGTDTQYVGKLHTD 80
T+LL+ + KK++ +LRR KR W + E G ++ ++ +D
Sbjct: 110 TVLLEHQ-------KKVSKTRHTRETVLRRAKRRWAPIPCSMQENSLGPFPLFLQQVESD 162
Query: 81 QDKGDGNLKYILTGDGAG----SLFVIDENTGDIHAAKKLDREEKSLYILRAKAIDRKTG 136
+ + + Y ++G G +LF I+ +TG++ + +DREE ++ L A A G
Sbjct: 163 AAQ-NYTVFYSISGRGVDKEPLNLFYIERDTGNLFCTRPVDREEYDVFDLIAYA-STADG 220
Query: 137 RQVEPESEFIIKIHDINDNEPKFTKDLYTASVPEMSGVGTSVIQVTATDADDANYGNSAK 196
+ I++ D NDN P FT+ +Y V E S GT+V V ATD D+ + ++ +
Sbjct: 221 YSADLPLPLPIRVEDENDNHPVFTEAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHT-R 279
Query: 197 VVYSILQGQP----YFSVDPESGIIKTALPDMSRENREQYQVVIQAKDMGGQMGGLSGTT 252
+ YSILQ P FSV P +G+I T + RE ++Y ++++ +DM GQ GL GT+
Sbjct: 280 LKYSILQQTPRSPGLFSVHPSTGVITTVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTS 339
Query: 253 TVNITLTDVNNNPPRFPQSTYQFNSPESVPLGTHLGRIKANDPDVGENAE--MEYSIAEG 310
T IT+TD N+N P F Q+ Y+ E+ + RI D D+ A + ++I +G
Sbjct: 340 TCIITVTDSNDNAPTFRQNAYEAFVEENA-FNVEILRIPIEDKDLINTANWRVNFTILKG 398
Query: 311 DGADMFDVITDKDTQEGIITVKQNLDFENQMLYTLRVDASNTHPDPRFLHLGPFKDTAVV 370
+ F + TDK+T EG+++V + L++E L + +N P R + + A+V
Sbjct: 399 NENGHFKISTDKETNEGVLSVVKPLNYEENRQVNLEIGVNNEAPFARDIPRVTALNRALV 458
Query: 371 KISVEDIDEPPVFTKVSYLIEVDEDVKEGSIIGQVTAYDPDARN-NLIKYSVDRHTDMDR 429
+ V D+DE P T + + + E++ GS I AYDP+ RN N ++Y + D
Sbjct: 459 TVHVRDLDEGPECTPAAQYVRIKENLAVGSKINGYKAYDPENRNGNGLRYK--KLHDPKG 516
Query: 430 IFGIHSENGSIFTLKALDRE----SSPWHNITVTATEINNPKQSSHIPVFIRILDINDHA 485
I +GSI T K LDRE + +NITV A I+ +S + + I D+ND+
Sbjct: 517 WITIDEISGSIITSKILDREVETPKNELYNITVLA--IDKDDRSCTGTLAVNIEDVNDNP 574
Query: 486 PEFAMYYETFVCENAKPGQLIQTVSVMDKDDPPRGHKFFFE-PVPEFTLNPNFTIVDNKD 544
PE Y +C KP + +D D+P G F+F P ++ +++ D
Sbjct: 575 PEILQEY-VVIC---KPKMGYTDILAVDPDEPVHGAPFYFSLPNTSPEISRLWSLTKVND 630
Query: 545 NTAGIMTRKDGYSRNKMSTYLLPILIFDNDYPIQSSTGTLTIRVCACDNQGNMQSCTAEA 604
A + +K+ Y +PI + D Q++T L + +C C + C A +
Sbjct: 631 TAARLSYQKNA----GFQEYTIPITV--KDRAGQAATKLLRVNLCECTHP---TQCRATS 681
Query: 605 LILSAGLSTGALVAILLCVLILLILVV-----LFAALKRQRKKEPLIISKDDVRDNIVTY 659
L A++AILL + +L +++ +F A K +R E L + N++
Sbjct: 682 RSTGVILGKWAILAILLGIALLFSVLLTLVCGVFGATKGKRFPEDL------AQQNLIIS 735
Query: 660 NDEGGGEE 667
N E G++
Sbjct: 736 NTEAPGDD 743
>gi|4826702 desmocollin 1 isoform Dsc1b preproprotein [Homo sapiens]
Length = 840
Score = 227 bits (578), Expect = 4e-59
Identities = 196/653 (30%), Positives = 320/653 (49%), Gaps = 50/653 (7%)
Query: 41 TKDDGKMLRRTKRGWMWNQFFLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILTGDGAG-- 98
TKD L+R+KR W L+E G Q+V ++ +D + + + Y ++G G
Sbjct: 124 TKDTA--LKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQ-NYTIFYSISGPGVDKE 180
Query: 99 --SLFVIDENTGDIHAAKKLDREEKSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNE 156
+LF I+++TGDI + +DRE+ + L A G E IIKI D NDN
Sbjct: 181 PFNLFYIEKDTGDIFCTRSIDREKYEQFALYGYATTAD-GYAPEYPLPLIIKIEDDNDNA 239
Query: 157 PKFTKDLYTASVPEMSGVGTSVIQVTATDADDANYGNSAKVVYSILQGQP----YFSVDP 212
P F + +VPE GTSV +VTATD D+ + ++ ++ Y ILQ P +FS+ P
Sbjct: 240 PYFEHRVTIFTVPENCRSGTSVGKVTATDLDEPDTLHT-RLKYKILQQIPDHPKHFSIHP 298
Query: 213 ESGIIKTALPDMSRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNNNPPRFPQST 272
++G+I T P + RE + YQ++++ +DMGGQ GL T T+ I+L D N+NPP F +++
Sbjct: 299 DTGVITTTTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETS 358
Query: 273 YQFNSPESVPLGTHLGRIKANDPDVGE--NAEMEYSIAEGDGADMFDVITDKDTQEGIIT 330
Y E + + R+K D D+ +++ Y I +G+ F + TD +T EG++
Sbjct: 359 Y-VTEVEENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLC 417
Query: 331 VKQNLDFENQMLYTLRVDASNTHPDPRFLHLG----PFKDTAVVKISVEDIDEPPVFTKV 386
V + L++E L+V N + +F P T V + + D DE P
Sbjct: 418 VVKPLNYEVNRQVILQVGVIN---EAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPP 474
Query: 387 SYLIEVDEDVKEGSIIGQVTAYDPD-ARNNLIKYSVDRHTDMDRIFGIHSENGSIFTLKA 445
+I+ + G + A DP+ + ++Y + D D F I+ G + TLK
Sbjct: 475 VKVIQSQDGFPAGQELLGYKALDPEISSGEGLRY--QKLGDEDNWFEINQHTGDLRTLKV 532
Query: 446 LDRES----SPWHNITVTATEINNPKQSSHIPVFIRILDINDHAPEFAMYYETFVCENAK 501
LDRES + +NI+V A ++ +S + + + D NDHAP+ E +C+N +
Sbjct: 533 LDRESKFVKNNQYNISVVA--VDAVGRSCTGTLVVHLDDYNDHAPQIDK--EVTICQNNE 588
Query: 502 PGQLIQTVSVMDKDDPPRGHKFFFEPVPEFTLNPNFTIVDNKDNTAGIMTRKDGYSRNKM 561
+++ V D D P G F F + N N ++ KD I+ ++ N
Sbjct: 589 DFAVLKPV---DPDGPENGPPFQFFLDNSASKNWN---IEEKDGKTAILRQRQNLDYN-- 640
Query: 562 STYLLPILIFDNDYPIQSSTGTLTIRVCACD--NQGNMQSCTAEALILSAGLSTGALVAI 619
Y +PI I D + +T LT+RVC C ++ M+ + + + L A++A+
Sbjct: 641 -YYSVPIQIKDRHGLV--ATHMLTVRVCDCSTPSECRMKDKSTRDVRPNVILGRWAILAM 697
Query: 620 LL-CVLILLILVVLFAALKRQRKKEPLIISKDDVRDNIVTYNDEGGGEEDTQA 671
+L VL+L IL F ++ K+ +D + N++ N EG GEE T+A
Sbjct: 698 VLGSVLLLCILFTCFCVTAKRTVKK--CFPEDIAQQNLIVSNTEGPGEEVTEA 748
>gi|13435361 desmocollin 1 isoform Dsc1a preproprotein [Homo
sapiens]
Length = 894
Score = 227 bits (578), Expect = 4e-59
Identities = 196/653 (30%), Positives = 320/653 (49%), Gaps = 50/653 (7%)
Query: 41 TKDDGKMLRRTKRGWMWNQFFLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILTGDGAG-- 98
TKD L+R+KR W L+E G Q+V ++ +D + + + Y ++G G
Sbjct: 124 TKDTA--LKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQ-NYTIFYSISGPGVDKE 180
Query: 99 --SLFVIDENTGDIHAAKKLDREEKSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNE 156
+LF I+++TGDI + +DRE+ + L A G E IIKI D NDN
Sbjct: 181 PFNLFYIEKDTGDIFCTRSIDREKYEQFALYGYATTAD-GYAPEYPLPLIIKIEDDNDNA 239
Query: 157 PKFTKDLYTASVPEMSGVGTSVIQVTATDADDANYGNSAKVVYSILQGQP----YFSVDP 212
P F + +VPE GTSV +VTATD D+ + ++ ++ Y ILQ P +FS+ P
Sbjct: 240 PYFEHRVTIFTVPENCRSGTSVGKVTATDLDEPDTLHT-RLKYKILQQIPDHPKHFSIHP 298
Query: 213 ESGIIKTALPDMSRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNNNPPRFPQST 272
++G+I T P + RE + YQ++++ +DMGGQ GL T T+ I+L D N+NPP F +++
Sbjct: 299 DTGVITTTTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETS 358
Query: 273 YQFNSPESVPLGTHLGRIKANDPDVGE--NAEMEYSIAEGDGADMFDVITDKDTQEGIIT 330
Y E + + R+K D D+ +++ Y I +G+ F + TD +T EG++
Sbjct: 359 Y-VTEVEENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLC 417
Query: 331 VKQNLDFENQMLYTLRVDASNTHPDPRFLHLG----PFKDTAVVKISVEDIDEPPVFTKV 386
V + L++E L+V N + +F P T V + + D DE P
Sbjct: 418 VVKPLNYEVNRQVILQVGVIN---EAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPP 474
Query: 387 SYLIEVDEDVKEGSIIGQVTAYDPD-ARNNLIKYSVDRHTDMDRIFGIHSENGSIFTLKA 445
+I+ + G + A DP+ + ++Y + D D F I+ G + TLK
Sbjct: 475 VKVIQSQDGFPAGQELLGYKALDPEISSGEGLRY--QKLGDEDNWFEINQHTGDLRTLKV 532
Query: 446 LDRES----SPWHNITVTATEINNPKQSSHIPVFIRILDINDHAPEFAMYYETFVCENAK 501
LDRES + +NI+V A ++ +S + + + D NDHAP+ E +C+N +
Sbjct: 533 LDRESKFVKNNQYNISVVA--VDAVGRSCTGTLVVHLDDYNDHAPQIDK--EVTICQNNE 588
Query: 502 PGQLIQTVSVMDKDDPPRGHKFFFEPVPEFTLNPNFTIVDNKDNTAGIMTRKDGYSRNKM 561
+++ V D D P G F F + N N ++ KD I+ ++ N
Sbjct: 589 DFAVLKPV---DPDGPENGPPFQFFLDNSASKNWN---IEEKDGKTAILRQRQNLDYN-- 640
Query: 562 STYLLPILIFDNDYPIQSSTGTLTIRVCACD--NQGNMQSCTAEALILSAGLSTGALVAI 619
Y +PI I D + +T LT+RVC C ++ M+ + + + L A++A+
Sbjct: 641 -YYSVPIQIKDRHGLV--ATHMLTVRVCDCSTPSECRMKDKSTRDVRPNVILGRWAILAM 697
Query: 620 LL-CVLILLILVVLFAALKRQRKKEPLIISKDDVRDNIVTYNDEGGGEEDTQA 671
+L VL+L IL F ++ K+ +D + N++ N EG GEE T+A
Sbjct: 698 VLGSVLLLCILFTCFCVTAKRTVKK--CFPEDIAQQNLIVSNTEGPGEEVTEA 748
>gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo
sapiens]
Length = 847
Score = 214 bits (545), Expect = 2e-55
Identities = 181/648 (27%), Positives = 310/648 (47%), Gaps = 53/648 (8%)
Query: 46 KMLRRTKRGWMWNQFFLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILTGDGAG----SLF 101
K+LRR KR W +LE G ++ ++ +D + + + Y + G G +LF
Sbjct: 128 KVLRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQ-NYTIYYSIRGPGVDQEPRNLF 186
Query: 102 VIDENTGDIHAAKKLDREEKSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTK 161
++ +TG+++ + +DRE+ + + A A G E IIKI D NDN P FT+
Sbjct: 187 YVERDTGNLYCTRPVDREQYESFEIIAFATT-PDGYTPELPLPLIIKIEDENDNYPIFTE 245
Query: 162 DLYTASVPEMSGVGTSVIQVTATDADDANYGNSAKVVYSILQGQP----YFSVDPESGII 217
+ YT ++ E VGT+V QV ATD D+ + ++ ++ YSI+ P FS+ P +G+I
Sbjct: 246 ETYTFTIFENCRVGTTVGQVCATDKDEPDTMHT-RLKYSIIGQVPPSPTLFSMHPTTGVI 304
Query: 218 KTALPDMSRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNNNPPRFPQSTYQFNS 277
T + RE ++YQ+ I+ +DM GQ GL T+T I + DVN++ P F +++Y S
Sbjct: 305 TTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSY-VTS 363
Query: 278 PESVPLGTHLGRIKANDPDVGENAEME--YSIAEGDGADMFDVITDKDTQEGIITVKQNL 335
E + + R+ D D+ A Y+I +G+ F ++TD T EG++ V + L
Sbjct: 364 VEENTVDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKPL 423
Query: 336 DFENQMLYTLRVDASNTHPDPRFLHLGPFKDTAVVKISVEDIDEPPVFTKVSYLIEVDED 395
++E + L++ N P R TA V ++VED DE P + + E+
Sbjct: 424 NYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMKEN 483
Query: 396 VKEGSIIGQVTAYDPDARNNL-IKYSVDRHTDMDRIFGIHSENGSIFTLKALDRES---- 450
+ G+ AYDP+ R++ I+Y + TD I GSI ++LDRE+
Sbjct: 484 AEVGTTSNGYKAYDPETRSSSGIRYK--KLTDPTGWVTIDENTGSIKVFRSLDREAETIK 541
Query: 451 SPWHNITVTATEINNPKQSSHIPVFIRILDINDHAPEFAMYYETFVCENAKPGQLIQTVS 510
+ +NITV A++ + + + ++ D+ND++P F +C KP +
Sbjct: 542 NGIYNITVLASDQGGRTCTGTLGIILQ--DVNDNSP-FIPKKTVIIC---KPTMSSAEIV 595
Query: 511 VMDKDDPPRGHKFFFEPVPEFTLNPNFTIVDN-------KDNTAGIMTRKDGYSRNKMST 563
+D D+P G F +F+L + + V D A + + D +
Sbjct: 596 AVDPDEPIHGPPF------DFSLESSTSEVQRMWRLKAINDTAARLSYQND----PPFGS 645
Query: 564 YLLPILIFDNDYPIQSSTGTLTIRVCACDNQGNMQSCT--AEALILSAGLSTG--ALVAI 619
Y++PI + D SS +L + +C C + + CT + I G+ G A++AI
Sbjct: 646 YVVPITV--RDRLGMSSVTSLDVTLCDCITEND---CTHRVDPRIGGGGVQLGKWAILAI 700
Query: 620 LLCVLILLILVVLFAALKRQRKKEPLIISKDDVRDNIVTYNDEGGGEE 667
LL + +L ++ K+P +I D + N++ N E G++
Sbjct: 701 LLGIALLFCILFTLVCGASGTSKQPKVIPDDLAQQNLIVSNTEAPGDD 748
>gi|13435364 desmocollin 2 isoform Dsc2a preproprotein [Homo
sapiens]
Length = 901
Score = 214 bits (545), Expect = 2e-55
Identities = 181/648 (27%), Positives = 310/648 (47%), Gaps = 53/648 (8%)
Query: 46 KMLRRTKRGWMWNQFFLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILTGDGAG----SLF 101
K+LRR KR W +LE G ++ ++ +D + + + Y + G G +LF
Sbjct: 128 KVLRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQ-NYTIYYSIRGPGVDQEPRNLF 186
Query: 102 VIDENTGDIHAAKKLDREEKSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTK 161
++ +TG+++ + +DRE+ + + A A G E IIKI D NDN P FT+
Sbjct: 187 YVERDTGNLYCTRPVDREQYESFEIIAFATT-PDGYTPELPLPLIIKIEDENDNYPIFTE 245
Query: 162 DLYTASVPEMSGVGTSVIQVTATDADDANYGNSAKVVYSILQGQP----YFSVDPESGII 217
+ YT ++ E VGT+V QV ATD D+ + ++ ++ YSI+ P FS+ P +G+I
Sbjct: 246 ETYTFTIFENCRVGTTVGQVCATDKDEPDTMHT-RLKYSIIGQVPPSPTLFSMHPTTGVI 304
Query: 218 KTALPDMSRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNNNPPRFPQSTYQFNS 277
T + RE ++YQ+ I+ +DM GQ GL T+T I + DVN++ P F +++Y S
Sbjct: 305 TTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSY-VTS 363
Query: 278 PESVPLGTHLGRIKANDPDVGENAEME--YSIAEGDGADMFDVITDKDTQEGIITVKQNL 335
E + + R+ D D+ A Y+I +G+ F ++TD T EG++ V + L
Sbjct: 364 VEENTVDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKPL 423
Query: 336 DFENQMLYTLRVDASNTHPDPRFLHLGPFKDTAVVKISVEDIDEPPVFTKVSYLIEVDED 395
++E + L++ N P R TA V ++VED DE P + + E+
Sbjct: 424 NYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMKEN 483
Query: 396 VKEGSIIGQVTAYDPDARNNL-IKYSVDRHTDMDRIFGIHSENGSIFTLKALDRES---- 450
+ G+ AYDP+ R++ I+Y + TD I GSI ++LDRE+
Sbjct: 484 AEVGTTSNGYKAYDPETRSSSGIRYK--KLTDPTGWVTIDENTGSIKVFRSLDREAETIK 541
Query: 451 SPWHNITVTATEINNPKQSSHIPVFIRILDINDHAPEFAMYYETFVCENAKPGQLIQTVS 510
+ +NITV A++ + + + ++ D+ND++P F +C KP +
Sbjct: 542 NGIYNITVLASDQGGRTCTGTLGIILQ--DVNDNSP-FIPKKTVIIC---KPTMSSAEIV 595
Query: 511 VMDKDDPPRGHKFFFEPVPEFTLNPNFTIVDN-------KDNTAGIMTRKDGYSRNKMST 563
+D D+P G F +F+L + + V D A + + D +
Sbjct: 596 AVDPDEPIHGPPF------DFSLESSTSEVQRMWRLKAINDTAARLSYQND----PPFGS 645
Query: 564 YLLPILIFDNDYPIQSSTGTLTIRVCACDNQGNMQSCT--AEALILSAGLSTG--ALVAI 619
Y++PI + D SS +L + +C C + + CT + I G+ G A++AI
Sbjct: 646 YVVPITV--RDRLGMSSVTSLDVTLCDCITEND---CTHRVDPRIGGGGVQLGKWAILAI 700
Query: 620 LLCVLILLILVVLFAALKRQRKKEPLIISKDDVRDNIVTYNDEGGGEE 667
LL + +L ++ K+P +I D + N++ N E G++
Sbjct: 701 LLGIALLFCILFTLVCGASGTSKQPKVIPDDLAQQNLIVSNTEAPGDD 748
>gi|4502719 cadherin 13 preproprotein [Homo sapiens]
Length = 713
Score = 214 bits (544), Expect = 3e-55
Identities = 187/621 (30%), Positives = 299/621 (48%), Gaps = 47/621 (7%)
Query: 32 LSSKKIAGLTKDDGKMLR-----RTKRGWMWNQFFLLEEYTGTDTQYVGKLHTDQDKGDG 86
+ K I G +D K R R KR + + + E + VGK+ D D+ +
Sbjct: 112 VGGKDIQGSLQDIFKFARTSPVPRQKRSIVVSPILIPENQRQPFPRDVGKV-VDSDRPER 170
Query: 87 NLKYILTGDGAGS----LFVIDENTGDIHAAKKLDREEKSLYILRAKAIDRKTGRQVEPE 142
+ K+ LTG G +F I+ENTG + + LDRE ++Y L + D G+ +E
Sbjct: 171 S-KFRLTGKGVDQEPKGIFRINENTGSVSVTRTLDREVIAVYQLFVETTD-VNGKTLEGP 228
Query: 143 SEFIIKIHDINDNEPKFTKDLYTASVPEMSGVGTSVIQVTATDADDANYGNSAKVVYSIL 202
+ + D NDN P F + Y V E S GT+V+++TA DADD N A + Y+I
Sbjct: 229 VPLEVIVIDQNDNRPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDN-ALLRYNIR 287
Query: 203 QGQP------YFSVDPESG----IIKTALPDMSRENREQYQVVIQAKDMGGQMGGLSGTT 252
Q P F +DPE G ++ AL D +Y+++I+A+DM G GL+GT
Sbjct: 288 QQTPDKPSPNMFYIDPEKGDIVTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTA 347
Query: 253 TVNITLTDVNNNPPRFPQSTYQFNSPE-SVPLGTHLGRIKANDPDVGENAEMEYSIAEGD 311
T I + D N++ P+F + +Q E +V + +L +DP G Y+I G+
Sbjct: 348 TATIMIDDKNDHSPKFTKKEFQATVEEGAVGVIVNLTVEDKDDPTTGA-WRAAYTIINGN 406
Query: 312 GADMFDVITDKDTQEGIITVKQNLDFENQMLYTLRVDASNTHPDPRFLHLGPFKDTAVVK 371
F++ T+ T EG+++V + LD+E +TL + N P + GP TA V
Sbjct: 407 PGQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGP-SSTATVH 465
Query: 372 ISVEDIDEPPVFTKVSYLIEVDEDVKEGSIIGQVTAYDPDA-RNNLIKYSVDRHTDMDRI 430
I+V D++E PVF ++ ED+ GS++ V A DPD+ ++ I+YSV + D
Sbjct: 466 ITVLDVNEGPVFYPDPMMVTRQEDLSVGSVLLTVNATDPDSLQHQTIRYSV--YKDPAGW 523
Query: 431 FGIHSENGSIFTLKALDRESSPWHNITVT----ATEINNPKQSSHIPVFIRILDINDHAP 486
I+ NG++ T LDRES N T A + NP + + I + D+ND+AP
Sbjct: 524 LNINPINGTVDTTAVLDRESPFVDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAP 583
Query: 487 EFAMYYETFVCENAKPGQLIQTVSVMDKDDPPRGHKFFFEPVPEFTLNPNFTIVDNKDNT 546
F VC++AK ++ + DKD P F FE + + + + +NT
Sbjct: 584 -FIYPTVAEVCDDAKNLSVV-ILGASDKDLHPNTDPFKFE-IHKQAVPDKVWKISKINNT 640
Query: 547 AGIMTRKDGYSRNKMSTYLLPILIFDNDYPIQSSTGTLTIRVCACDNQGNMQSCTAEALI 606
+++ ++ + Y LPI++ D+ P ++ L ++VC+C N + C A
Sbjct: 641 HALVSLLQNLNK---ANYNLPIMVTDSGKPPMTNITDLRVQVCSCRN--SKVDCNA---- 691
Query: 607 LSAGLSTGALVAILLCVLILL 627
AG +L ++LL L L
Sbjct: 692 --AGALRFSLPSVLLLSLFSL 710
>gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens]
Length = 4588
Score = 213 bits (542), Expect = 6e-55
Identities = 158/521 (30%), Positives = 252/521 (48%), Gaps = 38/521 (7%)
Query: 79 TDQDKG-DGNLKYILTGDGAGSLFVIDENTGDIHAAKKLDREEKSLYILRAKAIDRKTGR 137
TD D G +G L Y ++G S F+ID TG + LDRE Y L D +
Sbjct: 742 TDLDTGFNGKLVYAVSGGNEDSCFMIDMETGMLKILSPLDRETTDKYTLNITVYDLGIPQ 801
Query: 138 QVEPESEFIIKIHDINDNEPKFTKDLYTASVPEMSGVGTSVIQVTATDADDANYGNSAKV 197
+ ++ + D NDN P+F ++ Y V E V + +IQV ATD D G + V
Sbjct: 802 KAAWRLLHVVVV-DANDNPPEFLQESYFVEVSEDKEVHSEIIQVEATDKD---LGPNGHV 857
Query: 198 VYSILQGQPYFSVDPESGIIKTALPDMSRENREQYQVVIQAKDMGGQMGGLSGTTTVNIT 257
YSI+ FS+D +G++ A P + RE + ++ + I+A+D + L T V ++
Sbjct: 858 TYSIVTDTDTFSIDSVTGVVNIARP-LDRELQHEHSLKIEARDQAREEPQLFSTVVVKVS 916
Query: 258 LTDVNNNPPRFPQSTYQFNSPESVPLGTHLGRIKANDPDVGENAEMEYSIAEGDGADMFD 317
L DVN+NPP F Y+ E +P GT + ++A+DPD+G++ ++ YS+ + G FD
Sbjct: 917 LEDVNDNPPTFIPPNYRVKVREDLPEGTVIMWLEAHDPDLGQSGQVRYSLLD-HGEGNFD 975
Query: 318 VITDKDTQEGIITVKQNLDFENQMLYTLRVDASNTHPDPRFLHLGPFKDTAVVKISVEDI 377
V D G + + Q LDFE + +Y L V A + T V++ V D+
Sbjct: 976 V----DKLSGAVRIVQQLDFEKKQVYNLTVRAKDKGKPV------SLSSTCYVEVEVVDV 1025
Query: 378 DE---PPVFTKVSYLIEVDEDVKEGSIIGQVTAYDPDA-RNNLIKYSVDRHTDMDRIFGI 433
+E PPVF+ V ED GS++ V+A+D DA R+ I+YS+ R +F I
Sbjct: 1026 NENLHPPVFSSFVEKGTVKEDAPVGSLVMTVSAHDEDARRDGEIRYSI-RDGSGVGVFKI 1084
Query: 434 HSENGSIFTLKALDRESSPWHNITVTATEINNPKQSSHIPVFIRILDINDHAPEFA--MY 491
E G I T LDRES+ + +TV AT+ SS I ++I + D+ND+AP+ + +Y
Sbjct: 1085 GEETGVIETSDRLDRESTSHYWLTVFATDQGVVPLSSFIEIYIEVEDVNDNAPQTSEPVY 1144
Query: 492 YETFVCENAKPGQLIQTVSVMDKDDPPRGHKFF----FEPVPEFTLNPNFTIVDNKDNTA 547
Y + EN+ + + D D + P F+++P T
Sbjct: 1145 YPE-IMENSPKDVSVVQIEAFDPDSSSNDKLMYKITSGNPQGFFSIHP---------KTG 1194
Query: 548 GIMTRKDGYSRNKMSTYLLPILIFDNDYPIQSSTGTLTIRV 588
I T R + ++L + + DN P +S+ + +++
Sbjct: 1195 LITTTSRKLDREQQDEHILEVTVTDNGSPPKSTIARVIVKI 1235
Score = 206 bits (525), Expect = 5e-53
Identities = 164/522 (31%), Positives = 260/522 (49%), Gaps = 46/522 (8%)
Query: 79 TDQD-KGDGNLKYILTGDGAGSLFVIDENTGDIHAAKKLDREEKSLYILRAKAIDRKTGR 137
TD D + + + Y L G GA F ++ +TG++ + LDREE+++Y L +A D G
Sbjct: 3048 TDADIRSNAEITYTLLGSGAEK-FKLNPDTGELKTSTPLDREEQAVYHLLVRATD---GG 3103
Query: 138 QVEPESEFIIKIHDINDNEPKFTKDLYTASVPEMSGVGTSVIQVTATDADDANYGNSAKV 197
++ ++ + D+NDN P+F+ D Y +V E + GT + +V ATDAD G + K+
Sbjct: 3104 GRFCQASIVLTLEDVNDNAPEFSADPYAITVFENTEPGTLLTRVQATDADA---GLNRKI 3160
Query: 198 VYSILQGQP-YFSVDPESGIIKTALPDMSRENREQYQVVIQAKDMGGQMGGLSGTTTVNI 256
+YS++ FS++ SGII+ P + RE + Y + ++A D G L+ T TV +
Sbjct: 3161 LYSLIDSADGQFSINELSGIIQLEKP-LDRELQAVYTLSLKAVDQGLPRR-LTATGTVIV 3218
Query: 257 TLTDVNNNPPRFPQSTYQFNSPESVPLGTHLGRIKANDPDVGENAEMEYSIAEGDGADMF 316
++ D+N+NPP F Y E + +GT + ++ A D+ NAE+ YSI G+ F
Sbjct: 3219 SVLDINDNPPVFEYREYGATVSEDILVGTEVLQVYAASRDIEANAEITYSIISGNEHGKF 3278
Query: 317 DVITDKDTQEGIITVKQNLDFENQMLYTLRVDASNTHPDPRFLHLGPFKDTAVVKISVED 376
+ D++ G + + +NLD+E+ Y L V+A++ D A V ++V D
Sbjct: 3279 SI----DSKTGAVFIIENLDYESSHEYYLTVEATDGGTPS-------LSDVATVNVNVTD 3327
Query: 377 I-DEPPVFTKVSYLIEVDED-VKEGSIIGQVTAYDPDARNNL-IKYSVDRHTDMDRIFGI 433
I D PVF++ +Y + ED V E S+I V A D D +N I YS+ + F I
Sbjct: 3328 INDNTPVFSQDTYTTVISEDAVLEQSVI-TVMADDADGPSNSHIHYSII-DGNQGSSFTI 3385
Query: 434 HSENGSIFTLKALDRESSPWHNITVTATEINNPKQSSHIPVFIRILDINDHAPEFAM-YY 492
G + K LDRE+ + +TV A++ +P + + V I + D+ND+AP F+ Y
Sbjct: 3386 DPVRGEVKVTKLLDRETISGYTLTVQASDNGSPPRVNTTTVNIDVSDVNDNAPVFSRGNY 3445
Query: 493 ETFVCENAKPGQLIQTVSVMDKDDPPRGHKFFFEPVPEFTLNPNFTIVDNKD------NT 546
+ EN G + + V D+D G FFF TIV D N
Sbjct: 3446 SVIIQENKPVGFSVLQLVVTDEDSSHNGPPFFF------------TIVTGNDEKAFEVNP 3493
Query: 547 AGIMTRKDGYSRNKMSTYLLPILIFDNDYPIQSSTGTLTIRV 588
G++ R + YLL + + DN P SS + IRV
Sbjct: 3494 QGVLLTSSAIKRKEKDHYLLQVKVADNGKPQLSSLTYIDIRV 3535
Score = 172 bits (436), Expect = 1e-42
Identities = 156/539 (28%), Positives = 245/539 (45%), Gaps = 73/539 (13%)
Query: 79 TDQDKG-DGNLKYILTGDGAGSLFVIDENTGDIHAAKKLDREEKSLYILRAKAIDRKTGR 137
TD+D G +G++ Y + D F ID TG ++ A+ LDRE + + L+ +A D+
Sbjct: 847 TDKDLGPNGHVTYSIVTDT--DTFSIDSVTGVVNIARPLDRELQHEHSLKIEARDQA--- 901
Query: 138 QVEPE--SEFIIKI--HDINDNEPKFTKDLYTASVPEMSGVGTSVIQVTATDADDANYGN 193
+ EP+ S ++K+ D+NDN P F Y V E GT ++ + A D D G
Sbjct: 902 REEPQLFSTVVVKVSLEDVNDNPPTFIPPNYRVKVREDLPEGTVIMWLEAHDPD---LGQ 958
Query: 194 SAKVVYSILQ-GQPYFSVDPESGIIKTALPDMSRENREQYQVVIQAKDMGGQMGGLSGTT 252
S +V YS+L G+ F VD SG ++ + + E ++ Y + ++AKD G + LS T
Sbjct: 959 SGQVRYSLLDHGEGNFDVDKLSGAVRI-VQQLDFEKKQVYNLTVRAKDKGKPVS-LSSTC 1016
Query: 253 TVNITLTDVNNN--PPRFPQSTYQFNSPESVPLGTHLGRIKANDPDVGENAEMEYSIAEG 310
V + + DVN N PP F + E P+G+ + + A+D D + E+ YSI +G
Sbjct: 1017 YVEVEVVDVNENLHPPVFSSFVEKGTVKEDAPVGSLVMTVSAHDEDARRDGEIRYSIRDG 1076
Query: 311 DGADMFDVITDKDTQEGIITVKQNLDFENQMLYTLRVDASNTHPDPRFLHLGPFKDTAVV 370
G +F + + G+I LD E+ Y L V A++ + P +
Sbjct: 1077 SGVGVFKI----GEETGVIETSDRLDRESTSHYWLTVFATDQG-------VVPLSSFIEI 1125
Query: 371 KISVEDI-DEPPVFTKVSYLIEVDEDVKEGSIIGQVTAYDPDARNN-LIKYSVDRHTDMD 428
I VED+ D P ++ Y E+ E+ + + Q+ A+DPD+ +N + Y +
Sbjct: 1126 YIEVEDVNDNAPQTSEPVYYPEIMENSPKDVSVVQIEAFDPDSSSNDKLMYKITSGNPQG 1185
Query: 429 RIFGIHSENGSIFTL-KALDRESSPWHNITVTATEINNPKQSSHIPVFIRILDINDHAPE 487
F IH + G I T + LDRE H + VT T+ +P +S+ V ++ILD ND+ P+
Sbjct: 1186 -FFSIHPKTGLITTTSRKLDREQQDEHILEVTVTDNGSPPKSTIARVIVKILDENDNKPQ 1244
Query: 488 FAM-YYETFVCENAKPG-------QLIQTVSVMDKDDPPRGH------------KFFFEP 527
F +Y+ + E KP + + V DKD+ P KFF EP
Sbjct: 1245 FLQKFYKIRLPEREKPDRERNARREPLYHVIATDKDEGPNAEISYSIEDGNEHGKFFIEP 1304
Query: 528 VPEFTLNPNFTIVDNKDNTAGIMTRKDGYSRNKMSTYLLPILIFDNDYPIQSSTGTLTI 586
+ F+ D +L I DN P +SST L I
Sbjct: 1305 KTGVVSSKRFSAAGEYD--------------------ILSIKAVDNGRPQKSSTTRLHI 1343
Score = 168 bits (425), Expect = 2e-41
Identities = 134/444 (30%), Positives = 215/444 (48%), Gaps = 27/444 (6%)
Query: 79 TDQDKG-DGNLKYILTGDGAGSLFVIDENTGDIHAAKKLDREEKSLYILRAKAIDRKTGR 137
TD D G + + Y L D A F I+E +G I K LDRE +++Y L KA+D+ R
Sbjct: 3150 TDADAGLNRKILYSLI-DSADGQFSINELSGIIQLEKPLDRELQAVYTLSLKAVDQGLPR 3208
Query: 138 QVEPESEFIIKIHDINDNEPKFTKDLYTASVPEMSGVGTSVIQVTATDAD-DANYGNSAK 196
++ I+ + DINDN P F Y A+V E VGT V+QV A D +AN A+
Sbjct: 3209 RLTATGTVIVSVLDINDNPPVFEYREYGATVSEDILVGTEVLQVYAASRDIEAN----AE 3264
Query: 197 VVYSILQGQPY--FSVDPESGIIKTALPDMSRENREQYQVVIQAKDMGGQMGGLSGTTTV 254
+ YSI+ G + FS+D ++G + + ++ E+ +Y + ++A D G LS TV
Sbjct: 3265 ITYSIISGNEHGKFSIDSKTGAV-FIIENLDYESSHEYYLTVEATD--GGTPSLSDVATV 3321
Query: 255 NITLTDVNNNPPRFPQSTYQFNSPESVPLGTHLGRIKANDPDVGENAEMEYSIAEGDGAD 314
N+ +TD+N+N P F Q TY E L + + A+D D N+ + YSI +G+
Sbjct: 3322 NVNVTDINDNTPVFSQDTYTTVISEDAVLEQSVITVMADDADGPSNSHIHYSIIDGNQGS 3381
Query: 315 MFDVITDKDTQEGIITVKQNLDFENQMLYTLRVDASNTHPDPRFLHLGPFKDTAVVKISV 374
F + D G + V + LD E YTL V AS+ PR +T V I V
Sbjct: 3382 SFTI----DPVRGEVKVTKLLDRETISGYTLTVQASDNGSPPRV-------NTTTVNIDV 3430
Query: 375 EDI-DEPPVFTKVSYLIEVDEDVKEGSIIGQVTAYDPDARNNLIKYSVDRHTDMDRIFGI 433
D+ D PVF++ +Y + + E+ G + Q+ D D+ +N + T D
Sbjct: 3431 SDVNDNAPVFSRGNYSVIIQENKPVGFSVLQLVVTDEDSSHNGPPFFFTIVTGNDEKAFE 3490
Query: 434 HSENGSIFTLKALDRESSPWHNITVTATEINNPKQSSHIPVFIRILDINDHAPEFAMYYE 493
+ G + T A+ R+ + + V + P+ SS + IR+++ + + P + E
Sbjct: 3491 VNPQGVLLTSSAIKRKEKDHYLLQVKVADNGKPQLSSLTYIDIRVIEESIYPPAI-LPLE 3549
Query: 494 TFVCENAK--PGQLIQTVSVMDKD 515
F+ + + G +I + D+D
Sbjct: 3550 IFITSSGEEYSGGVIGKIHATDQD 3573
Score = 164 bits (415), Expect = 3e-40
Identities = 140/517 (27%), Positives = 237/517 (45%), Gaps = 30/517 (5%)
Query: 77 LHTDQDKGDG-NLKYILTGDGAGSLFVIDENTGDIHAAKKLDREEKSLYILRAKAIDRKT 135
+H + +G + Y +T S F I+ NTG I+ LD E Y L +A D T
Sbjct: 2202 VHVQANSPEGLKVFYSITDGDPFSQFTINFNTGVINVIAPLDFEAHPAYKLSIRATDSLT 2261
Query: 136 GRQVEPESEFIIKIHDINDNEPKFTKDLYTASVPEMSGVGTSVIQVTATDAD-DANYGNS 194
G E + I+ DINDN P F + Y ++ E S +GTSV+QV ATD+D + N G S
Sbjct: 2262 GAHAEVFVDIIVD--DINDNPPVFAQQSYAVTLSEASVIGTSVVQVRATDSDSEPNRGIS 2319
Query: 195 AKVVYSILQGQPYFSVDPESGIIKTALPDMSRENREQYQVVIQAKDMGGQMGGLSGTTTV 254
++ + + +F VD +G+I + L + E Q+ + ++A D G M LS V
Sbjct: 2320 YQMFGNHSKSHDHFHVDSSTGLI-SLLRTLDYEQSRQHTIFVRAVD--GGMPTLSSDVIV 2376
Query: 255 NITLTDVNNNPPRFPQSTYQFNSPESVPLGTHLGRIKANDPDVGENAEMEYSIAEGDGAD 314
+ +TD+N+NPP F Q Y+ E P G + +KA D D + +++YSI G+
Sbjct: 2377 TVDVTDLNDNPPLFEQQIYEARISEHAPHGHFVTCVKAYDADSSDIDKLQYSILSGNDHK 2436
Query: 315 MFDVITDKDTQEGIITVKQNLDFENQMLYTLRVDASNTHPDPRFLHLGPFKDTAVVKISV 374
F + D+ GIIT+ + Y+L + S+ G F+ + V ++V
Sbjct: 2437 HFVI----DSATGIITLSNLHRHALKPFYSLNLSVSD----------GVFRSSTQVHVTV 2482
Query: 375 EDID-EPPVFTKVSYLIEVDEDVKEGSIIGQVTAYDPDAR-NNLIKYSVDRHTDMDRIFG 432
+ P F + Y +E+ E+ +++ +V D D+ + Y + DR +
Sbjct: 2483 IGGNLHSPAFLQNEYEVELAENAPLHTLVMEVKTTDGDSGIYGHVTYHIVNDFAKDRFY- 2541
Query: 433 IHSENGSIFTLKALDRESSPWHNITVTATEINNPKQSSHIPVFIRILDINDHAPEF-AMY 491
+E G IFTL+ LDRE+ I+V + + + V + + D ND+AP+F A
Sbjct: 2542 -INERGQIFTLEKLDRETPAEKVISVRLMAKDAGGKVAFCTVNVILTDDNDNAPQFRATK 2600
Query: 492 YETFVCENAKPGQLIQTVSVMDKDDPPRGHKFFFEPVPEFTLNPNFTIVDNKDNTAGIMT 551
YE + +A G + V D D+ + ++ N I + +G++T
Sbjct: 2601 YEVNIGSSAAKGTSVVKVLASDADEGSNADITYAIEADSESVKENLEI----NKLSGVIT 2656
Query: 552 RKDGYSRNKMSTYLLPILIFDNDYPIQSSTGTLTIRV 588
K+ + + + DN P + S + +++
Sbjct: 2657 TKESLIGLENEFFTFFVRAVDNGSPSKESVVLVYVKI 2693
Score = 159 bits (403), Expect = 7e-39
Identities = 127/434 (29%), Positives = 219/434 (50%), Gaps = 33/434 (7%)
Query: 94 GDGAGSLFVIDENTGDIHAAKKLDREEKSLYILRAKAI--DRKTGRQVEPESEFIIKIHD 151
G+ + I+ H L EE + + A+ + K Q E E F H
Sbjct: 650 GENFATPLYINITVAASHKLVNLQCEETGVAKMLAEKLLQANKLHNQGEVEDIFFDS-HS 708
Query: 152 INDNEPKFTKDLYTA-SVPEMSGVGTSVIQVTATDADDANYGNSAKVVYSILQG--QPYF 208
+N + P+F L T V E VG+SVI + +TD D G + K+VY++ G F
Sbjct: 709 VNAHIPQFRSTLPTGIQVKENQPVGSSVIFMNSTDLDT---GFNGKLVYAVSGGNEDSCF 765
Query: 209 SVDPESGIIKTALPDMSRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNNNPPRF 268
+D E+G++K P + RE ++Y + I D+G + + +++ + D N+NPP F
Sbjct: 766 MIDMETGMLKILSP-LDRETTDKYTLNITVYDLG--IPQKAAWRLLHVVVVDANDNPPEF 822
Query: 269 PQSTYQFNSPESVPLGTHLGRIKANDPDVGENAEMEYSIAEGDGADMFDVITDKDTQEGI 328
Q +Y E + + + +++A D D+G N + YSI D F + D+ G+
Sbjct: 823 LQESYFVEVSEDKEVHSEIIQVEATDKDLGPNGHVTYSIV--TDTDTFSI----DSVTGV 876
Query: 329 ITVKQNLDFENQMLYTLRVDA-SNTHPDPRFLHLGPFKDTAVVKISVEDI-DEPPVFTKV 386
+ + + LD E Q ++L+++A +P+ T VVK+S+ED+ D PP F
Sbjct: 877 VNIARPLDRELQHEHSLKIEARDQAREEPQLF------STVVVKVSLEDVNDNPPTFIPP 930
Query: 387 SYLIEVDEDVKEGSIIGQVTAYDPD-ARNNLIKYSVDRHTDMDRIFGIHSENGSIFTLKA 445
+Y ++V ED+ EG++I + A+DPD ++ ++YS+ H + + F + +G++ ++
Sbjct: 931 NYRVKVREDLPEGTVIMWLEAHDPDLGQSGQVRYSLLDHGEGN--FDVDKLSGAVRIVQQ 988
Query: 446 LDRESSPWHNITVTATEINNP-KQSSHIPVFIRILDIND--HAPEFAMYYET-FVCENAK 501
LD E +N+TV A + P SS V + ++D+N+ H P F+ + E V E+A
Sbjct: 989 LDFEKKQVYNLTVRAKDKGKPVSLSSTCYVEVEVVDVNENLHPPVFSSFVEKGTVKEDAP 1048
Query: 502 PGQLIQTVSVMDKD 515
G L+ TVS D+D
Sbjct: 1049 VGSLVMTVSAHDED 1062
Score = 158 bits (399), Expect = 2e-38
Identities = 129/437 (29%), Positives = 209/437 (47%), Gaps = 41/437 (9%)
Query: 88 LKYILTGDGAGSLFVIDENTGDIHAAKKLDREEKSLYILRAKAIDRKTGRQVEPESEFII 147
L + +TG S F +D+ TG I AK LD E+KS Y L +A D T ++ I
Sbjct: 1389 LWFDITGGNYDSHFDVDKGTGTIIVAKPLDAEQKSNYNLTVEATDGTTTIL----TQVFI 1444
Query: 148 KIHDINDNEPKFTKDLYTASVPEMSGVGTSVIQVTATDADDANYGNSAKVVYSILQGQP- 206
K+ D ND+ P+F+ Y +PE + T ++Q++A D D+ N K++Y++ +
Sbjct: 1445 KVIDTNDHRPQFSTSKYEVVIPEDTAPETEILQISAVDQDEKN-----KLIYTLQSSRDP 1499
Query: 207 ----YFSVDPESGIIKTALPDMSRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVN 262
F +DP +G + T+ + E Q+ + + +D + VN++ D N
Sbjct: 1500 LSLKKFRLDPATGSLYTS-EKLDHEAVHQHTLTVMVRDQDVPVKRNFARIVVNVS--DTN 1556
Query: 263 NNPPRFPQSTYQFNSPESVPLGTHLGRIKANDPDVGENAEMEYSIAEGDGADMFDVITDK 322
++ P F S+Y+ ES +G+ + ++ A D D G+NAE+ YSI G+ + F +
Sbjct: 1557 DHAPWFTASSYKGRVYESAAVGSVVLQVTALDKDKGKNAEVLYSIESGNIGNSFMI---- 1612
Query: 323 DTQEGIITVKQNLDFENQMLYTLRVDASNTHPDPRFLHLGPFKDTAVVKISVEDIDE-PP 381
D G I + LD NQ Y L V A++ P + V+I V D P
Sbjct: 1613 DPVLGSIKTAKELDRSNQAEYDLMVKATDKGSP-------PMSEITSVRIFVTIADNASP 1665
Query: 382 VFTKVSYLIEVDEDVKEGSIIGQVTAYDPDARNNLIKYSVDRHTDMDRIFGIHSENGSIF 441
FT Y +E+ E V GS +G VTA+ + + Y + D F I+ +G+I
Sbjct: 1666 KFTSKEYSVELSETVSIGSFVGMVTAHSQSS----VVYEIKDGNTGD-AFDINPHSGTII 1720
Query: 442 TLKALDRESSPWHNITVTATEINNPKQSSHIPVFIRILDINDHAPEFAM-YYETFVCENA 500
T KALD E+ P + + + T N S++ V + + D ND+AP F Y + E+A
Sbjct: 1721 TQKALDFETLPIYTLIIQGT--NMAGLSTNTTVLVHLQDENDNAPVFMQAEYTGLISESA 1778
Query: 501 KPGQLIQTVSVMDKDDP 517
I +V + D++ P
Sbjct: 1779 S----INSVVLTDRNVP 1791
Score = 155 bits (392), Expect = 1e-37
Identities = 141/534 (26%), Positives = 243/534 (45%), Gaps = 63/534 (11%)
Query: 78 HTDQDKGDGNLKY-ILTGDGAGSLFVIDENTGDIHAAKKLDREEKSLYILRAKAIDRKTG 136
H + + DG ++Y I G G G +F I E TG I + +LDRE S Y L A D
Sbjct: 1059 HDEDARRDGEIRYSIRDGSGVG-VFKIGEETGVIETSDRLDRESTSHYWLTVFATD---- 1113
Query: 137 RQVEPESEFI---IKIHDINDNEPKFTKDLYTASVPEMSGVGTSVIQVTATDADDANYGN 193
+ V P S FI I++ D+NDN P+ ++ +Y + E S SV+Q+ A D D + +
Sbjct: 1114 QGVVPLSSFIEIYIEVEDVNDNAPQTSEPVYYPEIMENSPKDVSVVQIEAFDPDSS---S 1170
Query: 194 SAKVVYSILQGQP--YFSVDPESGIIKTALPDMSRENREQYQVVIQAKDMGGQMGGLSGT 251
+ K++Y I G P +FS+ P++G+I T + RE ++++ + + D G S
Sbjct: 1171 NDKLMYKITSGNPQGFFSIHPKTGLITTTSRKLDREQQDEHILEVTVTDNGSP--PKSTI 1228
Query: 252 TTVNITLTDVNNNPPRFPQSTYQFNSPESVPLGTH-------LGRIKANDPDVGENAEME 304
V + + D N+N P+F Q Y+ PE L + A D D G NAE+
Sbjct: 1229 ARVIVKILDENDNKPQFLQKFYKIRLPEREKPDRERNARREPLYHVIATDKDEGPNAEIS 1288
Query: 305 YSIAEGDGADMFDVITDKDTQEGIITVKQ-NLDFENQMLYTLRVDASNTHPDPRFLHLGP 363
YSI +G+ F + + + G+++ K+ + E +L VD N P
Sbjct: 1289 YSIEDGNEHGKFFI----EPKTGVVSSKRFSAAGEYDILSIKAVD--NGRP--------- 1333
Query: 364 FKDTAVVKISVEDID------EPPVFTKVSYLIEVDEDVKEGSIIGQVTAYDPDAR--NN 415
+ ++ ++ +E I EP F + + V E +IG ++ P +
Sbjct: 1334 -QKSSTTRLHIEWISKPKPSLEPISFEESFFTFTVMESDPVAHMIGVISVEPPGIPLWFD 1392
Query: 416 LIKYSVDRHTDMDRIFGIHSENGSIFTLKALDRESSPWHNITVTATEINNPKQSSHIPVF 475
+ + D H D+D+ G+I K LD E +N+TV AT+ + VF
Sbjct: 1393 ITGGNYDSHFDVDK------GTGTIIVAKPLDAEQKSNYNLTVEATDGTTTILTQ---VF 1443
Query: 476 IRILDINDHAPEFA-MYYETFVCENAKPGQLIQTVSVMDKDDPPRGHKFFFEPVPEFTLN 534
I+++D NDH P+F+ YE + E+ P I +S +D+D+ +K + + + +
Sbjct: 1444 IKVIDTNDHRPQFSTSKYEVVIPEDTAPETEILQISAVDQDEK---NKLIY--TLQSSRD 1498
Query: 535 PNFTIVDNKDNTAGIMTRKDGYSRNKMSTYLLPILIFDNDYPIQSSTGTLTIRV 588
P D G + + + + L +++ D D P++ + + + V
Sbjct: 1499 PLSLKKFRLDPATGSLYTSEKLDHEAVHQHTLTVMVRDQDVPVKRNFARIVVNV 1552
Score = 143 bits (360), Expect = 7e-34
Identities = 144/521 (27%), Positives = 235/521 (45%), Gaps = 40/521 (7%)
Query: 79 TDQDKG-DGNLKYILTGDGAGSL---FVIDENTGDIHAAKKLDREEKSLYILRAKAIDRK 134
+D D G +G + Y L + + F I+ TG I K+LD E++ Y ++ A D
Sbjct: 2834 SDADSGTNGQVMYSLDQSQSVEVIESFAINMETGWITTLKELDHEKRDNYQIKVVASDHG 2893
Query: 135 TGRQVEPESEFIIKIHDINDNEPKFTKDLYTASVPEMSGVGTSVIQVTATDADDANYGNS 194
Q+ + + + D+ND+ P+FT ++Y +V E G + ++ TDAD +
Sbjct: 2894 EKIQLSSTAIVDVTVTDVNDSPPRFTAEIYKGTVSEDDPQGGVIAILSTTDADSEEI--N 2951
Query: 195 AKVVYSILQGQP--YFSVDPESGIIKTAL-PDMSRENREQYQVVIQAKDMGGQMGGLSGT 251
+V Y I G P F+V+ K + + RE R+ Y + I A D G S
Sbjct: 2952 RQVTYFITGGDPLGQFAVETIQNEWKVYVKKPLDREKRDNYLLTITATD-----GTFSSK 3006
Query: 252 TTVNITLTDVNNNPPRFPQSTYQFNSPESVPLGTHLGRIKANDPDVGENAEMEYSIAEGD 311
V + + D N+N P ++ Y PE V G + +I A D D+ NAE+ Y++ G
Sbjct: 3007 AIVEVKVLDANDNSPVCEKTLYSDTIPEDVLPGKLIMQISATDADIRSNAEITYTLL-GS 3065
Query: 312 GADMFDVITDKDTQEGIITVKQNLDFENQMLYTLRVDASNTHPDPRFLHLGPFKDTAVVK 371
GA+ F + D G + LD E Q +Y L V A++ G F ++V
Sbjct: 3066 GAEKFKLNPD----TGELKTSTPLDREEQAVYHLLVRATDGG--------GRFCQASIV- 3112
Query: 372 ISVEDI-DEPPVFTKVSYLIEVDEDVKEGSIIGQVTAYDPDA-RNNLIKYSVDRHTDMDR 429
+++ED+ D P F+ Y I V E+ + G+++ +V A D DA N I YS+ D
Sbjct: 3113 LTLEDVNDNAPEFSADPYAITVFENTEPGTLLTRVQATDADAGLNRKILYSLIDSADGQ- 3171
Query: 430 IFGIHSENGSIFTLKALDRESSPWHNITVTATEINNPKQ-SSHIPVFIRILDINDHAPEF 488
F I+ +G I K LDRE + +++ A + P++ ++ V + +LDIND+ P F
Sbjct: 3172 -FSINELSGIIQLEKPLDRELQAVYTLSLKAVDQGLPRRLTATGTVIVSVLDINDNPPVF 3230
Query: 489 A-MYYETFVCENAKPGQLIQTVSVMDKDDPPRGHKFFFEPVPEFTLNPNFTIVDNKDNTA 547
Y V E+ G + V +D + + + F+I D+K
Sbjct: 3231 EYREYGATVSEDILVGTEVLQVYAASRDIEANAEITY--SIISGNEHGKFSI-DSKTGAV 3287
Query: 548 GIMTRKDGYSRNKMSTYLLPILIFDNDYPIQSSTGTLTIRV 588
I+ D S ++ Y L + D P S T+ + V
Sbjct: 3288 FIIENLDYESSHE---YYLTVEATDGGTPSLSDVATVNVNV 3325
Score = 131 bits (329), Expect = 3e-30
Identities = 144/561 (25%), Positives = 241/561 (42%), Gaps = 56/561 (9%)
Query: 80 DQDKGD-GNLKYILTGDGAGSLFVIDENTGDIHAAKKLDREEKSLYILRAKAIDR--KTG 136
D D D L+Y + FVID TG I + K Y L D ++
Sbjct: 2416 DADSSDIDKLQYSILSGNDHKHFVIDSATGIITLSNLHRHALKPFYSLNLSVSDGVFRSS 2475
Query: 137 RQVEPESEFIIKIHDINDNEPKFTKDLYTASVPEMSGVGTSVIQVTATDADDANYGNSAK 196
QV + + N + P F ++ Y + E + + T V++V TD D YG+
Sbjct: 2476 TQVH------VTVIGGNLHSPAFLQNEYEVELAENAPLHTLVMEVKTTDGDSGIYGH--- 2526
Query: 197 VVYSILQ--GQPYFSVDPESGIIKTALPDMSRENREQYQVVIQAKDMGGQMGGLSGTTTV 254
V Y I+ + F ++ I D + V + AKD GG++ TV
Sbjct: 2527 VTYHIVNDFAKDRFYINERGQIFTLEKLDRETPAEKVISVRLMAKDAGGKVA----FCTV 2582
Query: 255 NITLTDVNNNPPRFPQSTYQFNSPESVPLGTHLGRIKANDPDVGENAEMEYSIAEGDGAD 314
N+ LTD N+N P+F + Y+ N S GT + ++ A+D D G NA++ Y+I E D
Sbjct: 2583 NVILTDDNDNAPQFRATKYEVNIGSSAAKGTSVVKVLASDADEGSNADITYAI-EADSES 2641
Query: 315 MFDVITDKDTQEGIITVKQNLDFENQMLYTLRVDASNTHPDPRFLHLGPFKDTAV---VK 371
+ + + + + G+IT K++L +T V A + P K++ V VK
Sbjct: 2642 VKENL-EINKLSGVITTKESLIGLENEFFTFFVRAVDNG--------SPSKESVVLVYVK 2692
Query: 372 ISVEDIDEPPVFTKVSYLIEVDEDVKEGSIIGQVTA-YDPDARNNLIKYSVDRHTDMDRI 430
I ++ + P F++ Y V EDV G+ I + A + +L+K + ++ D
Sbjct: 2693 ILPPEM-QLPKFSEPFYTFTVSEDVPIGTEIDLIRAEHSGTVLYSLVKGNTP-ESNRDES 2750
Query: 431 FGIHSENGSIFTLKALDRESSPWHNITVTA-TEINNPKQSSHIPVFIRILDINDHAPEF- 488
F I ++G + K+LD E++ W+ ++ A ++ + + + V I++ D ND++P F
Sbjct: 2751 FVIDRQSGRLKLEKSLDHETTKWYQFSILARCTQDDHEMVASVDVSIQVKDANDNSPVFE 2810
Query: 489 AMYYETFVCENAKPGQLIQTVSVMDKDDPPRGHKFF-------FEPVPEFTLNPNFTIVD 541
+ YE F+ EN G + + D D G + E + F +N
Sbjct: 2811 SSPYEAFIVENLPGGSRVIQIRASDADSGTNGQVMYSLDQSQSVEVIESFAINM------ 2864
Query: 542 NKDNTAGIMTRKDGYSRNKMSTYLLPILIFDNDYPIQSSTGTLTIRVCACDNQGNMQSCT 601
T I T K+ K Y + ++ D+ IQ S+ T + V D + T
Sbjct: 2865 ---ETGWITTLKE-LDHEKRDNYQIKVVASDHGEKIQLSS-TAIVDVTVTDVNDSPPRFT 2919
Query: 602 AEAL--ILSAGLSTGALVAIL 620
AE +S G ++AIL
Sbjct: 2920 AEIYKGTVSEDDPQGGVIAIL 2940
Score = 125 bits (314), Expect = 2e-28
Identities = 109/362 (30%), Positives = 168/362 (46%), Gaps = 29/362 (8%)
Query: 91 ILTGDGAGSLFVIDENTGDIHAAKKLDREEKSLYILRAKAIDRKTGRQVEPESEFIIKIH 150
I++G+ G F ID TG + + LD E Y L +A D T + + + +
Sbjct: 3269 IISGNEHGK-FSIDSKTGAVFIIENLDYESSHEYYLTVEATDGGTP-SLSDVATVNVNVT 3326
Query: 151 DINDNEPKFTKDLYTASVPEMSGVGTSVIQVTATDADDANYGNSAKVVYSILQGQP--YF 208
DINDN P F++D YT + E + + SVI V A DAD + ++ + YSI+ G F
Sbjct: 3327 DINDNTPVFSQDTYTTVISEDAVLEQSVITVMADDADGPS---NSHIHYSIIDGNQGSSF 3383
Query: 209 SVDPESGIIK-TALPDMSRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNNNPPR 267
++DP G +K T L D RE Y + +QA D G TTTVNI ++DVN+N P
Sbjct: 3384 TIDPVRGEVKVTKLLD--RETISGYTLTVQASDNGSPPR--VNTTTVNIDVSDVNDNAPV 3439
Query: 268 FPQSTYQFNSPESVPLGTHLGRIKANDPDVGENAE-MEYSIAEGDGADMFDVITDKDTQE 326
F + Y E+ P+G + ++ D D N ++I G+ F+V +
Sbjct: 3440 FSRGNYSVIIQENKPVGFSVLQLVVTDEDSSHNGPPFFFTIVTGNDEKAFEV-----NPQ 3494
Query: 327 GIITVKQNLDFENQMLYTLRVD-ASNTHPDPRFLHLGPFKDTAVVKISVEDIDEPPVFTK 385
G++ + + + Y L+V A N P L + D V++ S+ PP
Sbjct: 3495 GVLLTSSAIKRKEKDHYLLQVKVADNGKPQLSSL---TYIDIRVIEESIY----PPAILP 3547
Query: 386 VSYLIEVDEDVKEGSIIGQVTAYDPDARNNLIKYSVDRHTDMDRIFGIHSENGSIFTLKA 445
+ I + G +IG++ A D D + L YS+D MD +F + S G + K
Sbjct: 3548 LEIFITSSGEEYSGGVIGKIHATDQDVYDTL-TYSLD--PQMDNLFSVSSTGGKLIAHKK 3604
Query: 446 LD 447
LD
Sbjct: 3605 LD 3606
Score = 124 bits (311), Expect = 3e-28
Identities = 130/483 (26%), Positives = 211/483 (43%), Gaps = 64/483 (13%)
Query: 80 DQDKGDGN--LKYILTGDGAGSLFVIDENTGDIHAAKKLDREEKSLYILRAKAIDRKTGR 137
D DK D N L Y + + F ID +TG IH LD EE S++ + D T R
Sbjct: 1798 DADK-DSNALLVYHIVEPSVHTYFAIDSSTGAIHTVLSLDYEETSIFHFTVQVHDMGTPR 1856
Query: 138 Q-VEPESEFIIKIHDINDNEPKFTKDLYTASVPEMSGVGTSVIQVTATDADDANYGNSAK 196
E + + + DIND P F K LY AS+ + G VI V ATDAD + + ++
Sbjct: 1857 LFAEYAANVTVHVIDINDCPPVFAKPLYEASLLLPTYKGVKVITVNATDADSSAF---SQ 1913
Query: 197 VVYSILQGQ--PYFSVDPESGIIKTALPDMSRENREQYQVVIQAKDMGGQMGGLSGTTTV 254
++YSI +G FS+D ++G + + + R +Y++ ++A D G +G T+V
Sbjct: 1914 LIYSITEGNIGEKFSMDYKTGALTV---QNTTQLRSRYELTVRASD-----GRFAGLTSV 1965
Query: 255 NITLTDVNNNPPRFPQSTYQFNSPESVPLGTHLGRIKANDPDVGE-------NAEMEYSI 307
I + + + +F Q Y E+ L I A + E N + + I
Sbjct: 1966 KINVKESKESHLKFTQDVYSAVVKENSTEAETLAVITAIGNPINEPLFYHILNPDRRFKI 2025
Query: 308 AEGDGADMFDVITDKDTQEGIITVKQNLDFENQMLYTLRVDASNTHPDPRFLHLGPFKDT 367
+ G + T D E Q + + V+ + H H+
Sbjct: 2026 SRTSGV--------------LSTTGTPFDREQQEAFDVVVEVTEEHKPSAVAHV------ 2065
Query: 368 AVVKISVED-IDEPPVFTKVSYLIEVDEDVKEGSIIGQVTAYDPDA-RNNLIKYSVDRHT 425
VVK+ VED D PVF + Y V D + G +I VTA D D+ RN + Y + H
Sbjct: 2066 -VVKVIVEDQNDNAPVFVNLPYYAVVKVDTEVGHVIRYVTAVDRDSGRNGEVHYYLKEHH 2124
Query: 426 DMDRIFGIHSEN-GSIFTLKALDRESSPWHNITVTATEINNPKQSSHIPVFIRILDINDH 484
+ +I + + F L L++E + +TV A + NP S+ + V I ++ N
Sbjct: 2125 EHFQIGPLGEISLKKQFELDTLNKE----YLVTVVAKDGGNPAFSAEVIVPITVM--NKA 2178
Query: 485 APEFAM-YYETFVCENAKPGQLIQTVSVMDKDDPPRGHKFFF-----EPVPEFTLNPNFT 538
P F +Y + E+ + + + V + + P G K F+ +P +FT+N N
Sbjct: 2179 MPVFEKPFYSAEIAESIQ----VHSPVVHVQANSPEGLKVFYSITDGDPFSQFTINFNTG 2234
Query: 539 IVD 541
+++
Sbjct: 2235 VIN 2237
Score = 109 bits (273), Expect = 9e-24
Identities = 126/469 (26%), Positives = 199/469 (42%), Gaps = 77/469 (16%)
Query: 101 FVIDENTGDIHAAKKLDRE-EKSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKF 159
F ID TG + ++ LD E +Y LR +A D + E E I ++++NDN P F
Sbjct: 510 FAIDHFTGAVSTSENLDYELMPRVYTLRIRASDWGLPYRREVEVLATITLNNLNDNTPLF 569
Query: 160 TKDLYTASVPEMSGVGTSVIQVTATDADDANYGNSAKVVYSILQGQP--YFSVDPESGII 217
K ++P GVG + V+A DAD+ V Y I G +FS++P SG++
Sbjct: 570 EKINCEGTIPRDLGVGEQITTVSAIDADELQL-----VQYQIEAGNELDFFSLNPNSGVL 624
Query: 218 --KTALPD------------MSRENREQYQ---------------VVIQAKDMGG----- 243
K +L D ++ + E + V +Q ++ G
Sbjct: 625 SLKRSLMDGLGAKVSFHSLRITATDGENFATPLYINITVAASHKLVNLQCEETGVAKMLA 684
Query: 244 ----QMGGLSGTTTVNITLTD---VNNNPPRFPQSTYQ--FNSPESVPLGTHLGRIKAND 294
Q L V D VN + P+F +ST E+ P+G+ + + + D
Sbjct: 685 EKLLQANKLHNQGEVEDIFFDSHSVNAHIPQF-RSTLPTGIQVKENQPVGSSVIFMNSTD 743
Query: 295 PDVGENAEMEYSIAEGDGADMFDVITDKDTQEGIITVKQNLDFENQMLYTLRVDASNTHP 354
D G N ++ Y+++ G+ F + D + G++ + LD E YTL + +
Sbjct: 744 LDTGFNGKLVYAVSGGNEDSCFMI----DMETGMLKILSPLDRETTDKYTLNITVYDLGI 799
Query: 355 DP----RFLHLGPFKDTAVVKISVEDIDEPPVFTKVSYLIEVDEDVKEGSIIGQVTAYDP 410
R LH+ + V+ D PP F + SY +EV ED + S I QV A D
Sbjct: 800 PQKAAWRLLHV----------VVVDANDNPPEFLQESYFVEVSEDKEVHSEIIQVEATDK 849
Query: 411 D-ARNNLIKYSVDRHTDMDRIFGIHSENGSIFTLKALDRESSPWHNITVTATE--INNPK 467
D N + YS+ TD F I S G + + LDRE H++ + A + P+
Sbjct: 850 DLGPNGHVTYSIVTDTD---TFSIDSVTGVVNIARPLDRELQHEHSLKIEARDQAREEPQ 906
Query: 468 QSSHIPVFIRILDINDHAPEF-AMYYETFVCENAKPGQLIQTVSVMDKD 515
S + V + + D+ND+ P F Y V E+ G +I + D D
Sbjct: 907 LFSTVVVKVSLEDVNDNPPTFIPPNYRVKVREDLPEGTVIMWLEAHDPD 955
Score = 108 bits (271), Expect = 1e-23
Identities = 115/477 (24%), Positives = 208/477 (43%), Gaps = 59/477 (12%)
Query: 87 NLKYILTGDGAGSLFVIDENTGDIHAAKKLDREEKSLYILRAKAIDRKTGRQVEPESEFI 146
+L+Y+ + F ++ NTG I + + R++ + + L DRK +V +
Sbjct: 397 HLRYVFKSTPGKAKFSLNYNTGLISILEPVKRQQAAHFELEVTTSDRKASTKV------L 450
Query: 147 IKIHDINDNEPKFTKDLYTASVPEMSGVGTSVIQVTATDADDANYGNSAKVVYSILQ-GQ 205
+K+ N N P+FT+ Y A+ E +GT+V+ ++A D D+ G + V YSI
Sbjct: 451 VKVLGANSNPPEFTQTAYKAAFDENVPIGTTVMSLSAVDPDE---GENGYVTYSIANLNH 507
Query: 206 PYFSVDPESGIIKTALPDMSRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNNNP 265
F++D +G + T+ Y + I+A D G ITL ++N+N
Sbjct: 508 VPFAIDHFTGAVSTSENLDYELMPRVYTLRIRASDWGLPY-RREVEVLATITLNNLNDNT 566
Query: 266 PRFPQSTYQFNSPESVPLGTHLGRIKANDPDVGENAEMEYSIAEGDGADMFDVITDKDTQ 325
P F + + P + +G + + A D D E ++Y I G+ D F + +
Sbjct: 567 PLFEKINCEGTIPRDLGVGEQITTVSAIDAD--ELQLVQYQIEAGNELDFFSL----NPN 620
Query: 326 EGIITVKQNLD---FENQMLYTLRVDASN--THPDPRFLHLG----------PFKDTAVV 370
G++++K++L ++LR+ A++ P ++++ ++T V
Sbjct: 621 SGVLSLKRSLMDGLGAKVSFHSLRITATDGENFATPLYINITVAASHKLVNLQCEETGVA 680
Query: 371 KI---------------SVEDI--DEPPVFTKVSYL-------IEVDEDVKEGSIIGQVT 406
K+ VEDI D V + I+V E+ GS + +
Sbjct: 681 KMLAEKLLQANKLHNQGEVEDIFFDSHSVNAHIPQFRSTLPTGIQVKENQPVGSSVIFMN 740
Query: 407 AYDPDAR-NNLIKYSVDRHTDMDRIFGIHSENGSIFTLKALDRESSPWHNITVTATEINN 465
+ D D N + Y+V + D F I E G + L LDRE++ + + +T ++
Sbjct: 741 STDLDTGFNGKLVYAVSGGNE-DSCFMIDMETGMLKILSPLDRETTDKYTLNITVYDLGI 799
Query: 466 PKQSSHIPVFIRILDINDHAPEFAM-YYETFVCENAKPGQLIQTVSVMDKDDPPRGH 521
P++++ + + ++D ND+ PEF Y V E+ + I V DKD P GH
Sbjct: 800 PQKAAWRLLHVVVVDANDNPPEFLQESYFVEVSEDKEVHSEIIQVEATDKDLGPNGH 856
Score = 103 bits (257), Expect = 6e-22
Identities = 98/411 (23%), Positives = 178/411 (43%), Gaps = 26/411 (6%)
Query: 116 LDREEKSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTKDLYTASVPEMSGVG 175
L+RE K Y L KA+++ T VE ++ +++ D ND P F+ Y+ S+PE + +
Sbjct: 108 LNREVKDHYTLIVKALEKNTN--VEARTKVRVQVLDTNDLRPLFSPTSYSVSLPENTAIR 165
Query: 176 TSVIQVTATDADDANYGNSAKVVYSILQGQPYFSVDPESGIIKTALPDMSRENREQYQVV 235
TS+ +V+ATDAD G + + YS F++ P SG+I + + Y++
Sbjct: 166 TSIARVSATDAD---IGTNGEFYYSFKDRTDMFAIHPTSGVI-VLTGRLDYLETKLYEME 221
Query: 236 IQAKDMGGQMGGLSGTTTVNITLTDVNNNPPRFPQSTYQFNSPESVPLGTHLGRIKANDP 295
I A D G ++ G SG +++ + P T SP + + +D
Sbjct: 222 ILAADRGMKLYGSSGISSMAKLTVHIEQANECAPVITAVTLSPSELDRDPAYAIVTVDDC 281
Query: 296 DVGENAEM-EYSIAEGDGADMFDVITD-KDTQEGIITVKQNLDFENQML-YTLRVDASNT 352
D G N ++ SI GD F + ++E + +D+++ Y L + A +
Sbjct: 282 DQGANGDIASLSIVAGDLLQQFRTVRSFPGSKEYKVKAIGGIDWDSHPFGYNLTLQAKDK 341
Query: 353 HPDPRFLHLGPFKDTAVVKISVEDIDEPPV-FTKVSYLIEVDEDVKEGSIIGQVTAYDPD 411
P+ F V+ ++ PV F K Y E+ E + + V A
Sbjct: 342 GTPPQ------FSSVKVIHVTSPQFKAGPVKFEKDVYRAEISEFAPPNTPVVMVKAIPAY 395
Query: 412 ARNNLIKYSVDRHTDMDRIFGIHSENGSIFTLKALDRESSPWHNITVTATEINNPKQSSH 471
+ ++Y V + T F ++ G I L+ + R+ + + VT ++ + +
Sbjct: 396 SH---LRY-VFKSTPGKAKFSLNYNTGLISILEPVKRQQAAHFELEVTTSD-----RKAS 446
Query: 472 IPVFIRILDINDHAPEFAM-YYETFVCENAKPGQLIQTVSVMDKDDPPRGH 521
V +++L N + PEF Y+ EN G + ++S +D D+ G+
Sbjct: 447 TKVLVKVLGANSNPPEFTQTAYKAAFDENVPIGTTVMSLSAVDPDEGENGY 497
Score = 101 bits (252), Expect = 2e-21
Identities = 90/348 (25%), Positives = 161/348 (46%), Gaps = 33/348 (9%)
Query: 124 YILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTKDLYTASVPEMSGVGTSVIQVTA 183
Y L +A D+ T Q + KF KD+Y A + E + T V+ V A
Sbjct: 332 YNLTLQAKDKGTPPQFSSVKVIHVTSPQFKAGPVKFEKDVYRAEISEFAPPNTPVVMVKA 391
Query: 184 TDADDANYGNSAKVVYSILQGQPYFSVDPESGIIKTALPDMSRENREQYQVVIQAKDMGG 243
A + + V+ G+ FS++ +G+I P + R+ +++ + D
Sbjct: 392 IPAY-----SHLRYVFKSTPGKAKFSLNYNTGLISILEP-VKRQQAAHFELEVTTSDR-- 443
Query: 244 QMGGLSGTTTVNITLTDVNNNPPRFPQSTYQFNSPESVPLGTHLGRIKANDPDVGENAEM 303
+T V + + N+NPP F Q+ Y+ E+VP+GT + + A DPD GEN +
Sbjct: 444 -----KASTKVLVKVLGANSNPPEFTQTAYKAAFDENVPIGTTVMSLSAVDPDEGENGYV 498
Query: 304 EYSIAEGDGADMFDVITDKDTQEGIITVKQNLDFE-NQMLYTLRVDASNTH-PDPRFLHL 361
YSI A++ V D G ++ +NLD+E +YTLR+ AS+ P R + +
Sbjct: 499 TYSI-----ANLNHVPFAIDHFTGAVSTSENLDYELMPRVYTLRIRASDWGLPYRREVEV 553
Query: 362 GPFKDTAVVKISVEDI-DEPPVFTKVSYLIEVDEDVKEGSIIGQVTAYDPDARNNLIKYS 420
+ I++ ++ D P+F K++ + D+ G I V+A D D L++Y
Sbjct: 554 -------LATITLNNLNDNTPLFEKINCEGTIPRDLGVGEQITTVSAIDAD-ELQLVQYQ 605
Query: 421 VDRHTDMDRIFGIHSENGSIFTLKALD---RESSPWHNITVTATEINN 465
++ ++D F ++ +G + ++L +H++ +TAT+ N
Sbjct: 606 IEAGNELD-FFSLNPNSGVLSLKRSLMDGLGAKVSFHSLRITATDGEN 652
Score = 78.6 bits (192), Expect = 2e-14
Identities = 121/512 (23%), Positives = 194/512 (37%), Gaps = 73/512 (14%)
Query: 63 LEEYTGTDTQYVGKLHTDQDKGDGNLKYILTGDGAGSLFVIDENTGDIHAAKKLDREEKS 122
L E T T TD D G Y D +F I +G I +LD E
Sbjct: 158 LPENTAIRTSIARVSATDADIGTNGEFYYSFKDRT-DMFAIHPTSGVIVLTGRLDYLETK 216
Query: 123 LYILRAKAIDRKT----GRQVEPESEFIIKIHDINDNEPKFTKDLYTASVPEMSGVGTSV 178
LY + A DR + ++ + I N+ P T T S E+
Sbjct: 217 LYEMEILAADRGMKLYGSSGISSMAKLTVHIEQANECAPVIT--AVTLSPSELDRDPAYA 274
Query: 179 IQVTATDADDANYGNSAK---VVYSILQ---------GQPYFSVDPESGIIKTALPDMSR 226
I VT D D G+ A V +LQ G + V GI + P
Sbjct: 275 I-VTVDDCDQGANGDIASLSIVAGDLLQQFRTVRSFPGSKEYKVKAIGGIDWDSHP---- 329
Query: 227 ENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNNNPPRFPQSTYQFNSPESVPLGTH 286
Y + +QAKD G S +++T P +F + Y+ E P T
Sbjct: 330 ---FGYNLTLQAKDK-GTPPQFSSVKVIHVTSPQFKAGPVKFEKDVYRAEISEFAPPNTP 385
Query: 287 LGRIKANDPDVGENAEMEYSIAEGDGADMFDVITDKDTQEGIITVKQNLDFENQMLYTLR 346
+ +KA + + + Y G F + + G+I++ + + + + L
Sbjct: 386 VVMVKA----IPAYSHLRYVFKSTPGKAKFSL----NYNTGLISILEPVKRQQAAHFELE 437
Query: 347 VDASNTHPDPRFLHLGPFKDTAVVKISVEDIDEPPVFTKVSYLIEVDEDVKEGSIIGQVT 406
V S+ + L VK+ + PP FT+ +Y DE+V G+ + ++
Sbjct: 438 VTTSDRKASTKVL----------VKVLGAN-SNPPEFTQTAYKAAFDENVPIGTTVMSLS 486
Query: 407 AYDPD-ARNNLIKYSVDRHTDMDRIFGIHSENGSIFTLKALDRESSP-WHNITVTATEIN 464
A DPD N + YS+ + F I G++ T + LD E P + + + A++
Sbjct: 487 AVDPDEGENGYVTYSIANLNHVP--FAIDHFTGAVSTSENLDYELMPRVYTLRIRASDWG 544
Query: 465 NP-KQSSHIPVFIRILDINDHAPEFAMYYETFVCENAKP-----GQLIQTVSVMDKDD-- 516
P ++ + I + ++ND+ P F E CE P G+ I TVS +D D+
Sbjct: 545 LPYRREVEVLATITLNNLNDNTPLF----EKINCEGTIPRDLGVGEQITTVSAIDADELQ 600
Query: 517 -----PPRGHKFFFEPVPEFTLNPNFTIVDNK 543
G++ F F+LNPN ++ K
Sbjct: 601 LVQYQIEAGNELDF-----FSLNPNSGVLSLK 627
Score = 74.3 bits (181), Expect = 4e-13
Identities = 80/335 (23%), Positives = 143/335 (42%), Gaps = 40/335 (11%)
Query: 224 MSRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNNNPPRFPQSTYQFNSPESVPL 283
++RE ++ Y ++++A + + T V + + D N+ P F ++Y + PE+ +
Sbjct: 108 LNREVKDHYTLIVKALEKNTNV---EARTKVRVQVLDTNDLRPLFSPTSYSVSLPENTAI 164
Query: 284 GTHLGRIKANDPDVGENAEMEYSIAEGDGADMFDVITDKDTQEGIITVKQNLDFENQMLY 343
T + R+ A D D+G N E YS D DMF + G+I + LD+ LY
Sbjct: 165 RTSIARVSATDADIGTNGEFYYSFK--DRTDMFAI----HPTSGVIVLTGRLDYLETKLY 218
Query: 344 TLRVDASNTHPDPRFLHLGPFKDTAVVKISVEDIDE-PPVFTKVSYLIEVDEDVKEGSII 402
+ + A++ + A + + +E +E PV T V+ L + D I
Sbjct: 219 EMEILAADR--GMKLYGSSGISSMAKLTVHIEQANECAPVITAVT-LSPSELDRDPAYAI 275
Query: 403 GQVTAYDPDARNNLIKYSVDRHTDMDRIFGIHSENGS----IFTLKALDRESSPW-HNIT 457
V D A ++ S+ + + + S GS + + +D +S P+ +N+T
Sbjct: 276 VTVDDCDQGANGDIASLSIVAGDLLQQFRTVRSFPGSKEYKVKAIGGIDWDSHPFGYNLT 335
Query: 458 VTATEINNPKQSSHIPVFIRILDINDHAPEFAM--------YYETFVCENAKPGQLIQTV 509
+ A + P Q S + V I+ +P+F Y + E A P T
Sbjct: 336 LQAKDKGTPPQFSSVKV------IHVTSPQFKAGPVKFEKDVYRAEISEFAPP----NTP 385
Query: 510 SVMDKDDPPRGH-KFFFEPVP---EFTLNPNFTIV 540
VM K P H ++ F+ P +F+LN N ++
Sbjct: 386 VVMVKAIPAYSHLRYVFKSTPGKAKFSLNYNTGLI 420
>gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens]
Length = 4981
Score = 196 bits (497), Expect = 9e-50
Identities = 151/528 (28%), Positives = 249/528 (47%), Gaps = 33/528 (6%)
Query: 85 DGNLKYILTGDGAGSLFVIDENTGDIHAAKKLDREEKSLYILRAKAID----RKTGRQVE 140
+G +KY ++ +F I+ +TG + AK LD E + + AID +TG
Sbjct: 3121 NGLIKYSISSGNEEGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGY--- 3177
Query: 141 PESEFIIKIHDINDNEPKFTKDLYTASVPEMSGVGTSVIQVTATDADDANYGNSAKVVYS 200
+ + D+NDN P F D Y +V E + GT+VI + ATDAD G +A + Y+
Sbjct: 3178 --CSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADS---GTNAVIAYT 3232
Query: 201 ILQGQP-YFSVDPESGIIKTALPDMSRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLT 259
+ F +DP +G+I T + E ++ Y + ++A ++ + TVNI L
Sbjct: 3233 VQSSDSDLFVIDPNTGVITTQ-GFLDFETKQSYHLTVKAFNVPDEER--CSFATVNIQLK 3289
Query: 260 DVNNNPPRFPQSTYQFNSPESVPLGTHLGRIKANDPDVGENAEMEYSIAEGDGADMFDVI 319
N PRF Y F E+ P GT +G + A+D D+G + E+ Y I F +
Sbjct: 3290 GTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQI- 3348
Query: 320 TDKDTQEGIITVKQNLDFENQMLYTLRVDASNTHPDPRFLHLGPFKDTAVVKISVEDIDE 379
+ + G I V LD E + +L+V A N G D V ++V D ++
Sbjct: 3349 ---NKKTGQIYVSGILDREKEERVSLKVLAKNFGS-----IRGADIDEVTVNVTVLDAND 3400
Query: 380 PPVFTKVSYLIEVDEDVKEGSIIGQVTAYDPDARNNLIKYSVDRHTDMDR-IFGIHSENG 438
PP+FT Y +++ E V G+ + V+A+D D+ + ++S + + F I+ + G
Sbjct: 3401 PPIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGNENGAFSINPQTG 3460
Query: 439 SIFTLKALDRESSPWHNITVTATEINNPKQSSHIPVFIRILDINDHAPEFAMYYETFVCE 498
I LDRE+ P +N++V A + P + + + + DIND+ P + E V E
Sbjct: 3461 QITVTAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDINDNGPMLTV-SEGEVME 3519
Query: 499 NAKPGQLIQTVSVMDKDDPPRGHKFFFEPVPEFTLNPNFTIVDNKDNTAGIMTRKDGYSR 558
N +PG L+ T+ D D PP F + + F++ +TAG+++ R
Sbjct: 3520 NKRPGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSL-----STAGVLSTTREIDR 3574
Query: 559 NKMSTYLLPILIFDNDYPIQSSTGTLTIRVCACDNQGNMQSCTAEALI 606
+++ + L ++ D+ P SSTGT+ I V N QS T E +
Sbjct: 3575 EQIADFYLSVVTKDSGVPQMSSTGTVHITVID-QNDNPSQSRTVEIFV 3621
Score = 190 bits (483), Expect = 4e-48
Identities = 154/503 (30%), Positives = 244/503 (48%), Gaps = 48/503 (9%)
Query: 98 GSLFVIDENTGDIHAAKKLDREEKS-LYILRAKAIDRKTGRQVEPESEFIIKIHDINDNE 156
G LF I +TG I A LDRE+ + LY++ AI++ T +E I + DINDN
Sbjct: 1678 GRLFTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKSTAFPRTQRAEVEITLQDINDNP 1737
Query: 157 PKFTKDLYTASVPEMSGVGTSVIQVTATDADDANYGNSAKVVYSILQG-QPYFSVDPESG 215
P F D+ +V E G G+ ++Q+TA DAD+ G +A V Y+I+ G F +DPESG
Sbjct: 1738 PVFPTDMLDLTVEENIGDGSKIMQLTAMDADE---GANALVTYTIISGADDSFRIDPESG 1794
Query: 216 IIKTALPDMSRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNNNPPRFPQSTYQF 275
+ A + RE R +Y ++++A D G S +NIT++DVN++ P+F + Y F
Sbjct: 1795 DL-IATRRLDRERRSKYSLLVRADD-----GLQSSDMRINITVSDVNDHTPKFSRPVYSF 1848
Query: 276 NSPESVPLGTHLGRIKANDPDVGENAEMEYSIAEGDGADMFDVITDKDTQEGIITVKQNL 335
+ PE G+ + I A D D G N E+ Y + E D +F + + G+ + + L
Sbjct: 1849 DIPEDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFFL----NPITGVFNLTRLL 1904
Query: 336 DFENQMLYTLRVDASNTHPDPRFLHLGPFKDTAVVKISVEDIDEPPVFTKVSYLIEVDED 395
D+E Q Y L V A + G F V ++ D PP+F+ SY + E+
Sbjct: 1905 DYEVQQYYILTVRAEDGG--------GQFTTIRVYFNILDVNDNPPIFSLNSYSTSLMEN 1956
Query: 396 VKEGS--IIGQVTAYDPDARNNLIKYSVDRHTDMDRIFGIHSENGSIFTLKALDRESSPW 453
+ GS ++ VT D D N+ + YS+ + + +NG + LKALDRES +
Sbjct: 1957 LPVGSTVLVFNVTDAD-DGINSQLTYSIASGDSLGQF--TVDKNGVLKVLKALDRESQSF 2013
Query: 454 HNITVTA---TEINNPKQSSHIPVFIRILDINDHAPEFAMYYETFVCENAKPGQLIQTVS 510
+N+ V +I + +S V I +LD+ND+ P F T++ EN ++
Sbjct: 2014 YNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLTYIPENTPIDTVVFKAQ 2073
Query: 511 VMDKDDPPRGHKFFFEPVPEFTLNP---NFTI--VDNKDNTAGIMTRKDGYSRNKMSTYL 565
D D P + + LNP F+I +D + G + R++ +S Y
Sbjct: 2074 ATDPDSGPNSY------IEYTLLNPLGNKFSIGTIDGEVRLTGELDREE------VSNYT 2121
Query: 566 LPILIFDNDYPIQSSTGTLTIRV 588
L ++ D P SS+ + + V
Sbjct: 2122 LTVVATDKGQPSLSSSTEVVVMV 2144
Score = 189 bits (479), Expect = 1e-47
Identities = 161/530 (30%), Positives = 254/530 (47%), Gaps = 37/530 (6%)
Query: 63 LEEYTGTDTQYVGKLHTDQDKGDGNLKYILTGDGAGSLFVIDENTGDIHAAKKLDREEKS 122
+EE G ++ + D D+G L GA F ID +GD+ A ++LDRE +S
Sbjct: 1749 VEENIGDGSKIMQLTAMDADEGANALVTYTIISGADDSFRIDPESGDLIATRRLDRERRS 1808
Query: 123 LYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTKDLYTASVPEMSGVGTSVIQVT 182
Y L +A D G Q + I + D+ND+ PKF++ +Y+ +PE + G+ V +
Sbjct: 1809 KYSLLVRADD---GLQ-SSDMRINITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAIL 1864
Query: 183 ATDADDANYGNSAKVVYSILQGQP--YFSVDPESGIIK-TALPDMSRENREQYQVVIQAK 239
ATD D G + ++ Y + + F ++P +G+ T L D E ++ Y + ++A+
Sbjct: 1865 ATDDDS---GVNGEITYIVNEDDEDGIFFLNPITGVFNLTRLLDY--EVQQYYILTVRAE 1919
Query: 240 DMGGQMGGLSGTTTVNITLTDVNNNPPRFPQSTYQFNSPESVPLGTHLGRIKANDPDVGE 299
D GGQ T V + DVN+NPP F ++Y + E++P+G+ + D D G
Sbjct: 1920 DGGGQFT----TIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGI 1975
Query: 300 NAEMEYSIAEGDGADMFDVITDKDTQEGIITVKQNLDFENQMLYTLRVDASNTHPDPRFL 359
N+++ YSIA GD F V DK+ G++ V + LD E+Q Y L V H P+ +
Sbjct: 1976 NSQLTYSIASGDSLGQFTV--DKN---GVLKVLKALDRESQSFYNLVV---QVHDLPQ-I 2026
Query: 360 HLGPFKDTAVVKISVEDI-DEPPVFTKVSYLIEVDEDVKEGSIIGQVTAYDPDA-RNNLI 417
F TA V I + D+ D PP F L + E+ +++ + A DPD+ N+ I
Sbjct: 2027 PASRFTSTAQVSIILLDVNDNPPTFLSPK-LTYIPENTPIDTVVFKAQATDPDSGPNSYI 2085
Query: 418 KYSVDRHTDMDRIFGIHSENGSIFTLKALDRESSPWHNITVTATEINNPKQSSHIPVFIR 477
+Y++ + F I + +G + LDRE + +TV AT+ P SS V +
Sbjct: 2086 EYTL--LNPLGNKFSIGTIDGEVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVM 2143
Query: 478 ILDINDHAPEFAM-YYETFVCENAKPGQLIQTVSVMDKDDPPRGHKFFFEPVPEFTLNPN 536
+LDIND+ P FA Y+ + EN G I V D D+ G + + N
Sbjct: 2144 VLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRY--GIVNGNTNQE 2201
Query: 537 FTIVDNKDNTAGIMTRKDGYSRNKMSTYLLPILIFDNDYPIQSSTGTLTI 586
F I D+ G +T R K TY L + D ++ T T++I
Sbjct: 2202 FRI----DSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSI 2247
Score = 186 bits (471), Expect = 1e-46
Identities = 160/559 (28%), Positives = 260/559 (46%), Gaps = 47/559 (8%)
Query: 73 YVGKLHTDQDKGDGNLKYILTGDGAGSLFVIDENTGDIHAAKKLDREEKSLYILRAKAID 132
+VG + + N+ Y++T +F I++ TG + A +DREE+S Y L+ A
Sbjct: 811 HVGSVSASTMDLNSNISYLITTGDQKGMFAINQVTGQLTTANVIDREEQSFYQLKVVA-- 868
Query: 133 RKTGRQVEPESEFIIKIHDINDNEPKFTKDLYTASVPEMSGVGTSVIQVTATDADDANYG 192
+G V ++ I + D+NDN P F + + + +V E G S+ Q A D D+ G
Sbjct: 869 --SGGTVTGDTMVNITVKDLNDNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDE---G 923
Query: 193 NSAKVVYSILQG-QPYFSVDPESGIIKTALPDMSRENREQYQVVIQAKDMGGQMGGLSGT 251
+ V+YS+ Q + F+++ ++G I P + YQ+ I A DMG + LS +
Sbjct: 924 VNGMVLYSLKQNPKNLFAINEKNGTISLLGP--LDVHAGSYQIEILASDMG--VPQLSSS 979
Query: 252 TTVNITLTDVNNNPPRFPQSTYQFNSPESVPLGTHLGRIKANDPDVGENAEMEYSIAEGD 311
+ + + DVN+N P F Q +Y+ ES P+ + +++A+D D G N E+ Y+IAEG+
Sbjct: 980 VILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQASDKDSGANGEIAYTIAEGN 1039
Query: 312 GADMFDVITDKDTQEGIITVKQNLDFENQMLYTLRVDASNTHPDPRFLHLGPFKDTAVVK 371
D F + D G + +K LD E Q Y L V AS+ + P T V
Sbjct: 1040 TGDAFGIFPD-----GQLYIKSELDRELQDRYVLMVVASDRAVE-------PLSATVNVT 1087
Query: 372 ISVEDI-DEPPVFTKVSYLIEVDEDVKEGSIIGQVTAYDPD-ARNNLIKYSVDRHTDMDR 429
+ +ED+ D P+F +Y +E+ + GS +G+V+A D D N ++YS + +
Sbjct: 1088 VILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYSFEM---VQP 1144
Query: 430 IFGIHSENGSIFTLKALDRES------SPWHNITVTATEINNPKQ-SSHIPVFIRILDIN 482
F +H+ +G I DRES + + TV AT+ P+ V + + DIN
Sbjct: 1145 DFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHVYMKDIN 1204
Query: 483 DHAPEFAM-YYETFVCENAKPGQLIQTVSVMDKDDPPRGHKFFFEPVPEFTLNPNFTIVD 541
D+AP+F +Y+ + E+A + VS D D+ G + + F I
Sbjct: 1205 DNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNG--LIHYSIIKGNEERQFAI-- 1260
Query: 542 NKDNTAGIMTRKDGYSRNKMSTYLLPILIFDNDYPIQSSTGTLTIRVCACDNQGNMQSCT 601
D+T+G +T Y L I D+ +ST TL I + D N S
Sbjct: 1261 --DSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDI--LDENDNTPSFP 1316
Query: 602 AEALILSA--GLSTGALVA 618
L + + G LV+
Sbjct: 1317 KSTLFVDVLENMRIGELVS 1335
Score = 176 bits (447), Expect = 6e-44
Identities = 130/446 (29%), Positives = 225/446 (50%), Gaps = 22/446 (4%)
Query: 80 DQDKG-DGNLKYILTGDGAGSLFVIDENTGDIHAAKKLDREEKSLYILRAKAIDRKTGRQ 138
D+D G +G L Y + + F I+ TG+I + + LDRE+ S Y+L K+ D+ + Q
Sbjct: 2694 DKDSGPNGQLDYEIVNGNMENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQ 2753
Query: 139 VEPESEFIIKIHDINDNEPKFTKDLYTASVPEMSGVGTSVIQVTATDADDANYGNSAKVV 198
+ +I I D NDN P+F++ +++A VPE S +G +V +VT +D D G +A
Sbjct: 2754 -STSVKVMINILDENDNAPRFSQ-IFSAHVPENSPLGYTVTRVTTSDED---IGINAISR 2808
Query: 199 YSILQGQPYFSVDPESGIIKTALPDMSRENREQYQVVIQAKDMGGQMGGLSGTTTVNITL 258
YSI+ F+++P +G I + P ++RE+ ++Y++ + A D G + +T V I +
Sbjct: 2809 YSIMDASLPFTINPSTGDIVISRP-LNREDTDRYRIRVSAHDSGWTV-----STDVTIFV 2862
Query: 259 TDVNNNPPRFPQSTYQFNSPESVPLGTHLGRIKANDPDVGENAEMEYSIAEGDGADMFDV 318
TD+N+N PRF +++Y + PE +G+ + ++ A DPD G N ++ Y I +
Sbjct: 2863 TDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFYFIKSQSEYFRINA 2922
Query: 319 ITDKDTQEGIITVKQNLDFENQMLYTLR-VDASNTHPDPRFLHLGPFKDTAVVKISVEDI 377
T + + I+ + F N + + S+ P + +T V V+
Sbjct: 2923 TTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLI-----SETTVTINIVDSN 2977
Query: 378 DEPPVFTKVSYLIEVDEDVKEGSIIGQVTAYDPD--ARNNLIKYSVDRHTDMDRIFGIHS 435
D P F K Y V ++VK G+ + +VTA D N+ ++Y + + + F + +
Sbjct: 2978 DNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGK-FKLDN 3036
Query: 436 ENGSIFTLKALDRESSPWHNITVTATEINNPKQSSHIPVFIRILDINDHAPEFAM-YYET 494
+ G I +L + + ITVTA + NP SS V I + + N H PEF+ +
Sbjct: 3037 DTGWISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEFSQSHMSA 3096
Query: 495 FVCENAKPGQLIQTVSVMDKDDPPRG 520
+ E+ G +++TVS D+D G
Sbjct: 3097 TIPESHSIGSIVRTVSARDRDAAMNG 3122
Score = 176 bits (446), Expect = 8e-44
Identities = 140/476 (29%), Positives = 230/476 (48%), Gaps = 37/476 (7%)
Query: 60 FFLLEEYTGTDTQYVGKLHT-DQDKG-DGNLKYILTGDGAGSLFVIDENTGDIHAAKKLD 117
+F E+ G+ +VGK+ D+D G +G ++Y + F + +G+I + D
Sbjct: 1108 YFEEEQRAGS---FVGKVSAVDKDFGPNGEVRYSF--EMVQPDFELHAISGEITNTHQFD 1162
Query: 118 REE------KSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTKDLYTASVPEM 171
RE +++ A D+ + ++ ++ + + DINDN PKF KD Y A++ E
Sbjct: 1163 RESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQATISES 1222
Query: 172 SGVGTSVIQVTATDADDANYGNSAKVVYSILQG--QPYFSVDPESGIIKTALPDMSRENR 229
+ T V++V+A+D D+ GN+ + YSI++G + F++D SG + T + + E
Sbjct: 1223 AANLTQVLRVSASDVDE---GNNGLIHYSIIKGNEERQFAIDSTSGQV-TLIGKLDYEAT 1278
Query: 230 EQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNNNPPRFPQSTYQFNSPESVPLGTHLGR 289
Y +VIQA D G L+ T T+NI + D N+N P FP+ST + E++ +G +
Sbjct: 1279 PAYSLVIQAVDSGTIP--LNSTCTLNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSS 1336
Query: 290 IKANDPDVGENAEMEYSIAEGDGADMFDVITDKDTQEGIITVKQNLDFENQMLYTLRVDA 349
+ A D D G+NA++ YSI + F + G I + + LDFE Q LY L + A
Sbjct: 1337 VTATDSDSGDNADLYYSITGTNNHGTFSI----SPNTGSIFLAKKLDFETQSLYKLNITA 1392
Query: 350 SNTHPDPRFLHLGPFKDTAVVKISVEDI-DEPPVFTKVSYLIEVDEDVKEGSIIGQVTAY 408
+ PR T V I V D D PP F + E++ G+ + VTA+
Sbjct: 1393 KDQGRPPR-------SSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIPIGTSVISVTAH 1445
Query: 409 DPDAR-NNLIKYSVDRHTDMDRIFGIHSENGSIFTLKALDRESSPWHNITVTATEINNPK 467
DPDA N + Y++ + F I G+I+T +DRE + +TV A + P
Sbjct: 1446 DPDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTNAEIDREFANLFELTVKANDQAVPI 1505
Query: 468 QSSHIP---VFIRILDINDHAPEFAMYYETFVCENAKPGQLIQTVSVMDKDDPPRG 520
++ V I + D+ND+ P F +A G ++ T+ D D+ G
Sbjct: 1506 ETRRYALKNVTILVTDLNDNVPMFISQNALAADPSAVIGSVLTTIMAADPDEGANG 1561
Score = 171 bits (432), Expect = 3e-42
Identities = 155/562 (27%), Positives = 258/562 (45%), Gaps = 55/562 (9%)
Query: 80 DQDKG-DGNLKYILTGDGAGSLFVIDENTGDIHAAKKLDREEKSLYILRAKAIDRK---- 134
D D+G + +++Y L +G F +D TG I + LD E + Y L +A+DR
Sbjct: 276 DADEGTNADIRYRLQDEGTP--FQMDPETGLITVREPLDFEARRQYSLTVQAMDRGVPSL 333
Query: 135 TGRQVEPESEFIIKIHDINDNEPK-----FTKDLYTASVPEMSGVGTSVIQVTATDADDA 189
TGR +E +I++ D+NDN+P F ASV E + VGT V +T TDAD
Sbjct: 334 TGR-----AEALIQLLDVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSP 388
Query: 190 NYGNSAKVVYSILQG--QPYFSVD----PESGIIKTALPDMSRENREQYQVVIQAKDMGG 243
+ V IL G Q +F V P +IK A + RE Y + + D G
Sbjct: 389 AANGNISV--QILGGNEQRHFEVQSSKVPNLSLIKVASA-LDRERIPSYNLTVSVSDNYG 445
Query: 244 QMGGL-----SGTTTVNITLTDVNNNPPRFPQSTYQFNSPESVPLGTHLGRIKANDPDVG 298
G S ++ I + D+N++PP F Q Y+ N E P G+++ I A D D G
Sbjct: 446 APPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSG 505
Query: 299 ENAEMEYSIAEGDGADMFDVITDKDTQEGIITVKQN--LDFENQMLYTLRVDASNTHPDP 356
NA + YSI G+G F + G++T + LD E L + A + P
Sbjct: 506 LNANLRYSIVSGNGLGWFHI----SEHSGLVTTGSSGGLDRELASQIVLNISARDQGVHP 561
Query: 357 RFLHLGPFKDTAVVKISVEDI-DEPPVFTK-VSYLIEVDEDVKEGSIIGQVTAYDPD-AR 413
+ + A + +++ D+ DE PVF++ Y + V E+ G+ + + A D D
Sbjct: 562 KVSY-------AQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTELLMLRATDGDLGD 614
Query: 414 NNLIKYSVDRHTDMDRIFGIHSENGSIFTLKALDRESSPWHNITVTATEINNPKQSSHIP 473
N +++S+ R F + +G + T+ +LDRE ++++ V AT++ +P QSS
Sbjct: 615 NGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLGSPPQSSMAR 674
Query: 474 VFIRILDINDHAPEF-AMYYETFVCENAKPGQLIQTVSVMDKDDPPRGHKFFFEPVPEFT 532
+ + +LDIND++P F + Y + EN G I TVS D D G +++
Sbjct: 675 INVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGTNG-------TVKYS 727
Query: 533 LNPNFTIVDNKDNTAGIMTRKDGYSRNKMSTYLLPILIFDNDYPIQSSTGTLTIRVCACD 592
++ + +G+++ + R + + Y L I+ D + +TI V
Sbjct: 728 ISAGDRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTITVLDTQ 787
Query: 593 NQGNMQSCTAEALILSAGLSTG 614
+ + S A + ++ ++ G
Sbjct: 788 DNPPVFSQVAYSFVVFENVALG 809
Score = 168 bits (426), Expect = 2e-41
Identities = 147/529 (27%), Positives = 238/529 (44%), Gaps = 38/529 (7%)
Query: 63 LEEYTGTDTQYVGKLHTDQDKG-DGNLKYILTGDGAGSLFVIDENTGDIHAAKKLDREEK 121
L E ++++ +D+D G +G + Y + G F I + G ++ +LDRE +
Sbjct: 1005 LSESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFPD-GQLYIKSELDRELQ 1063
Query: 122 SLYILRAKAIDRKTGRQVEPESEFI---IKIHDINDNEPKFTKDLYTASVPEMSGVGTSV 178
Y+L A DR VEP S + + + D+NDN P F YT E G+ V
Sbjct: 1064 DRYVLMVVASDRA----VEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFV 1119
Query: 179 IQVTATDADDANYGNSAKVVYSILQGQPYFSVDPESG-IIKTALPD----MSRENREQYQ 233
+V+A D D +G + +V YS QP F + SG I T D M R +
Sbjct: 1120 GKVSAVDKD---FGPNGEVRYSFEMVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFS 1176
Query: 234 VVIQAKDMGGQMGGLSGTTTVNITLTDVNNNPPRFPQSTYQFNSPESVPLGTHLGRIKAN 293
+ A D G L TV++ + D+N+N P+F + YQ ES T + R+ A+
Sbjct: 1177 FTVIATDQGIPQP-LKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSAS 1235
Query: 294 DPDVGENAEMEYSIAEGDGADMFDVITDKDTQEGIITVKQNLDFENQMLYTLRVDASNTH 353
D D G N + YSI +G+ F + D+ G +T+ LD+E Y+L + A ++
Sbjct: 1236 DVDEGNNGLIHYSIIKGNEERQFAI----DSTSGQVTLIGKLDYEATPAYSLVIQAVDSG 1291
Query: 354 PDPRFLHLGPFKDTAVVKISV-EDIDEPPVFTKVSYLIEVDEDVKEGSIIGQVTAYDPDA 412
P T + I + ++ D P F K + ++V E+++ G ++ VTA D D+
Sbjct: 1292 TIP-------LNSTCTLNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDS 1344
Query: 413 RNNLIKYSVDRHTDMDRIFGIHSENGSIFTLKALDRESSPWHNITVTATEINNPKQSSHI 472
+N Y T+ F I GSIF K LD E+ + + +TA + P +SS +
Sbjct: 1345 GDNADLYYSITGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTM 1404
Query: 473 PVFIRILDINDHAPEF--AMYYETFVCENAKPGQLIQTVSVMDKDDPPRGHKFFFEPVPE 530
V I + D ND+ P F +++ V EN G + +V+ D D G + + + +
Sbjct: 1405 SVVIHVRDFNDNPPSFPPGDIFKSIV-ENIPIGTSVISVTAHDPDADING-QLSYTIIQQ 1462
Query: 531 FTLNPNFTIVDNKDNTAGIMTRKDGYSRNKMSTYLLPILIFDNDYPIQS 579
+FTI D G + R + + L + D PI++
Sbjct: 1463 MPRGNHFTI----DEVKGTIYTNAEIDREFANLFELTVKANDQAVPIET 1507
Score = 167 bits (423), Expect = 3e-41
Identities = 153/528 (28%), Positives = 239/528 (45%), Gaps = 39/528 (7%)
Query: 65 EYTGTDTQYVGKLHTDQDKGD-GNLKYILT-GDGAGSLFVIDENTGDIHAAKKLDREEKS 122
E T T+ + TD D GD G +++ L + F +D +G + LDREE++
Sbjct: 594 ENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQA 653
Query: 123 LYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTKDLYTASVPEMSGVGTSVIQVT 182
Y L A D + Q + + + DINDN P F Y A + E G+ + V+
Sbjct: 654 FYSLLVLATDLGSPPQ-SSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVS 712
Query: 183 ATDADDANYGNSAKVVYSILQG-QPYFSVDPESGIIKTALPDMSRENREQYQVVIQAKDM 241
ATD D G + V YSI G + F V+ +SG+I T + + RE + YQ+ I A D
Sbjct: 713 ATDPD---LGTNGTVKYSISAGDRSRFQVNAQSGVISTRMA-LDREEKTAYQLQIVATDG 768
Query: 242 GGQMGGLSGTTTVNITLTDVNNNPPRFPQSTYQFNSPESVPLGTHLGRIKANDPDVGENA 301
G V IT+ D +NPP F Q Y F E+V LG H+G + A+ D+ N+
Sbjct: 769 GNLQS--PNQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDL--NS 824
Query: 302 EMEYSIAEGDGADMFDVITDKDTQEGIITVKQNLDFENQMLYTLRVDASNTHPDPRFLHL 361
+ Y I GD MF + + G +T +D E Q Y L+V AS
Sbjct: 825 NISYLITTGDQKGMFAI----NQVTGQLTTANVIDREEQSFYQLKVVASG---------- 870
Query: 362 GPFKDTAVVKISVEDI-DEPPVFTKVSYLIEVDEDVKEGSIIGQVTAYDPD-ARNNLIKY 419
G +V I+V+D+ D P F + + V E+ + G I Q A DPD N ++ Y
Sbjct: 871 GTVTGDTMVNITVKDLNDNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLY 930
Query: 420 SVDRHTDMDRIFGIHSENGSIFTLKALDRESSPWHNITVTATEINNPKQSSHIPVFIRIL 479
S+ ++ +F I+ +NG+I L LD + + I + A+++ P+ SS + + + +
Sbjct: 931 SLKQNP--KNLFAINEKNGTISLLGPLDVHAGS-YQIEILASDMGVPQLSSSVILTVYVH 987
Query: 480 DINDHAPEF-AMYYETFVCENAKPGQLIQTVSVMDKDDPPRGHKFFFEPVPEFTLNPNFT 538
D+ND++P F + YE + E+ V DKD G + + E F
Sbjct: 988 DVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQASDKDSGANGEIAY--TIAEGNTGDAFG 1045
Query: 539 IVDNKDNTAGIMTRKDGYSRNKMSTYLLPILIFDNDYPIQSSTGTLTI 586
I + G + K R Y+L ++ D S+T +T+
Sbjct: 1046 IFPD-----GQLYIKSELDRELQDRYVLMVVASDRAVEPLSATVNVTV 1088
Score = 164 bits (415), Expect = 3e-40
Identities = 141/512 (27%), Positives = 237/512 (46%), Gaps = 37/512 (7%)
Query: 80 DQDKGDGN-LKYILTGDGAGSLFVIDENTGDIHAAKKLDREEKSLYILRAKAIDRKTGRQ 138
D D+G + L Y+L G + F + + G++ + LDRE K ++L A D +
Sbjct: 2286 DDDRGSNSKLSYVLFGGNEDNAFTLSAS-GELGVTQSLDRETKERFVLMITATDSGSPAL 2344
Query: 139 VEPESEFIIKIHDINDNEPKFTKDLYTASVPEMSGVGTSVIQVTATDADDANYGNSAKVV 198
+ +I + D+NDN P F Y ++PE + GT V+ V A+DAD S V
Sbjct: 2345 TGTGTINVI-VDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADA-----SKNAV 2398
Query: 199 YSILQGQPYFSVDPESG-IIKTALPDMSRENREQYQVVIQAKDMGGQMGGLSGTTTVNIT 257
I+ G F+++P +G II +AL D RE ++ Y +V+ D G LS +T+V +T
Sbjct: 2399 IRIIGGNSQFTINPSTGQIITSALLD--RETKDNYTLVVVCSDAGSPEP-LSSSTSVLVT 2455
Query: 258 LTDVNNNPPRFPQSTYQFNSPESVPLGTHLGRIKANDPDVGENAEMEYSIAEGDGADMFD 317
+TDVN+NPPRF Y + P G+ + + D D+G N+E+ YS++ G ++ F
Sbjct: 2456 VTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYSLS-GRNSEKFH 2514
Query: 318 VITDKDTQEGIITVKQNLDFENQMLYTLRVDASNTHPDPRFLHLGPFKDTAVVKISVEDI 377
+ D G I L+ +++ +++ V + P T V V
Sbjct: 2515 I----DPLRGAIMAAGPLNGASEVTFSVHVKDGGSFPKT--------DSTTVTVRFVNKA 2562
Query: 378 DEPPVFTKVSYLIEVDEDVKEGSIIGQVTAYDPDARNNLIKYSVDRHTDMDRIFGIHSEN 437
D P V K + E+ S++ +T R + Y + ++ F I
Sbjct: 2563 DFPKVRAKEQTFM-FPENQPVSSLVTTITG--SSLRGEPMSYYI-ASGNLGNTFQIDQLT 2618
Query: 438 GSIFTLKALDRESSPWHNITVTATEINNPKQSSHIPVFIRILDINDHAPEFAMY-YETFV 496
G + + LD E + + + A + P SS+ + I +LD+ND+AP F + + +
Sbjct: 2619 GQVSISQPLDFEKIQKYVVWIEARDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISEI 2678
Query: 497 CENAKPGQLIQTVSVMDKDDPPRGHKFFFEPVPEFTLNPNFTIVDNKDNTAGIMTRKDGY 556
EN P +++ TVS MDKD P G + + + +F+I ++ G +
Sbjct: 2679 LENLSPRKIL-TVSAMDKDSGPNGQLDY--EIVNGNMENSFSI----NHATGEIRSVRPL 2731
Query: 557 SRNKMSTYLLPILIFDNDYPIQSSTGTLTIRV 588
R K+S Y+L I D P QS++ + I +
Sbjct: 2732 DREKVSHYVLTIKSSDKGSPSQSTSVKVMINI 2763
Score = 155 bits (392), Expect = 1e-37
Identities = 145/452 (32%), Positives = 209/452 (46%), Gaps = 36/452 (7%)
Query: 79 TDQDKGDG-NLKYILTGDGAGSLFVIDENTGDIHAAKKLDREEKSLYILRAKAIDRKTGR 137
TD D GD +L Y +TG F I NTG I AKKLD E +SLY L A D+ GR
Sbjct: 1340 TDSDSGDNADLYYSITGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQ--GR 1397
Query: 138 QVEPES-EFIIKIHDINDNEPKFTKDLYTASVPEMSGVGTSVIQVTATDAD-DANYGNSA 195
+ +I + D NDN P F S+ E +GTSVI VTA D D D N
Sbjct: 1398 PPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDADIN----G 1453
Query: 196 KVVYSILQGQP---YFSVDPESGIIKTALPDMSRENREQYQVVIQAKDMGGQMGGLS-GT 251
++ Y+I+Q P +F++D G I T ++ RE +++ ++A D +
Sbjct: 1454 QLSYTIIQQMPRGNHFTIDEVKGTIYTNA-EIDREFANLFELTVKANDQAVPIETRRYAL 1512
Query: 252 TTVNITLTDVNNNPPRFPQSTYQFNSPESVPLGTHLGRIKANDPDVGENAEMEYSIAEGD 311
V I +TD+N+N P F P +V +G+ L I A DPD G N E+EY I GD
Sbjct: 1513 KNVTILVTDLNDNVPMFISQNALAADPSAV-IGSVLTTIMAADPDEGANGEIEYEIINGD 1571
Query: 312 GADMFDVITDKDTQEGIITVKQNLDFENQMLYTLRVDASNTHPDPRFLHLGPFKDTAVVK 371
D F V D G + V L +Q++Y L V A++ P+ R K T +
Sbjct: 1572 -TDTFIV----DRYSGDLRVASAL-VPSQLIYNLIVSATDLGPERR-------KSTTELT 1618
Query: 372 ISVEDIDEPPVFTKVSYLIEVDEDVKEGSIIGQVTAYDPDARNNLIKYSV----DRHTDM 427
I ++ +D PVFT+ Y+ + E G+ + + A P ++Y + +
Sbjct: 1619 IILQGLD-GPVFTQPKYITILKEGEPIGTNVISIEAASPRGSEAPVEYYIVSVRCEEKTV 1677
Query: 428 DRIFGIHSENGSIFTLKALDRESSP-WHNITVTATEINNP-KQSSHIPVFIRILDINDHA 485
R+F I G I T LDRE + + V A E + ++ V I + DIND+
Sbjct: 1678 GRLFTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKSTAFPRTQRAEVEITLQDINDNP 1737
Query: 486 PEFAM-YYETFVCENAKPGQLIQTVSVMDKDD 516
P F + V EN G I ++ MD D+
Sbjct: 1738 PVFPTDMLDLTVEENIGDGSKIMQLTAMDADE 1769
Score = 151 bits (381), Expect = 3e-36
Identities = 125/454 (27%), Positives = 204/454 (44%), Gaps = 37/454 (8%)
Query: 67 TGTDTQYVGKLHTDQDKGDGNLKYILTGDGAGSLFVIDENTGDIHAAKKLDREEKSLYIL 126
TGTD V D K ++ G S F I+ +TG I + LDRE K Y L
Sbjct: 2379 TGTDVLLVNASDADASKNA-----VIRIIGGNSQFTINPSTGQIITSALLDRETKDNYTL 2433
Query: 127 RAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTKDLYTASVPEMSGVGTSVIQVTATDA 186
D + + + ++ + D+NDN P+F Y +P + G+ V VT TDA
Sbjct: 2434 VVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDA 2493
Query: 187 DDANYGNSAKVVYSIL-QGQPYFSVDPESGIIKTALPDMSRENREQYQVVIQAKDMGGQM 245
D G ++++ YS+ + F +DP G I A P + + KD GG
Sbjct: 2494 D---IGPNSELHYSLSGRNSEKFHIDPLRGAIMAAGP---LNGASEVTFSVHVKD-GGSF 2546
Query: 246 GGLSGTTTVNITLTDVNNNPPRFPQSTYQF--NSPESVPLGTHLGRIKANDPDVGENAEM 303
TT + + R + T+ F N P S + T G +P M
Sbjct: 2547 PKTDSTTVTVRFVNKADFPKVRAKEQTFMFPENQPVSSLVTTITGSSLRGEP-------M 2599
Query: 304 EYSIAEGDGADMFDVITDKDTQEGIITVKQNLDFENQMLYTLRVDASNTHPDPRFLHLGP 363
Y IA G+ + F + D G +++ Q LDFE Y + ++A + P
Sbjct: 2600 SYYIASGNLGNTFQI----DQLTGQVSISQPLDFEKIQKYVVWIEARDGG-------FPP 2648
Query: 364 FKDTAVVKISVEDI-DEPPVFTKVSYLIEVDEDVKEGSIIGQVTAYDPDAR-NNLIKYSV 421
F + I+V D+ D P+F + ++ E+ E++ I+ V+A D D+ N + Y +
Sbjct: 2649 FSSYEKLDITVLDVNDNAPIFKEDPFISEILENLSPRKIL-TVSAMDKDSGPNGQLDYEI 2707
Query: 422 DRHTDMDRIFGIHSENGSIFTLKALDRESSPWHNITVTATEINNPKQSSHIPVFIRILDI 481
+ +M+ F I+ G I +++ LDRE + +T+ +++ +P QS+ + V I ILD
Sbjct: 2708 V-NGNMENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVMINILDE 2766
Query: 482 NDHAPEFAMYYETFVCENAKPGQLIQTVSVMDKD 515
ND+AP F+ + V EN+ G + V+ D+D
Sbjct: 2767 NDNAPRFSQIFSAHVPENSPLGYTVTRVTTSDED 2800
Score = 138 bits (348), Expect = 2e-32
Identities = 126/446 (28%), Positives = 197/446 (44%), Gaps = 50/446 (11%)
Query: 99 SLFVIDENTGDIHAAKKLDREEKSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPK 158
+LF I+ +TG ++ +DRE ++ + E + + D+NDN P
Sbjct: 79 ALFAINSSTGALYTTSTIDRESLPSDVINLVVLSSAPTYPTEVR----VLVRDLNDNAPV 134
Query: 159 FTKDLYTASVPEMSGVGTSVIQVTATDADDANYGNSAKVVYSILQGQPY------FSVDP 212
F + E S G VI TATD+D + G + Y I++G +++P
Sbjct: 135 FPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRS-YRIIRGNEAGRFRLDITLNP 193
Query: 213 ESG---IIKTALPDMSRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNNNPPRFP 269
+ + + RE QYQ++++ +D G G VN+T+ D+N+NPP F
Sbjct: 194 SGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKR--RGYLQVNVTVQDINDNPPVFG 251
Query: 270 QSTYQFNSPESVPLGTHLGRIKANDPDVGENAEMEYSIA-EGDGADMFDVITDKDTQEGI 328
S YQ PE +G+ + ++ A D D G NA++ Y + EG M D + G+
Sbjct: 252 SSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTPFQM-------DPETGL 304
Query: 329 ITVKQNLDFENQMLYTLRVDASNTHPDPRFLHLGPFKDTAVVKISVEDIDEPPV-----F 383
ITV++ LDFE + Y+L V A D L + + + V D D PV F
Sbjct: 305 ITVREPLDFEARRQYSLTVQAM----DRGVPSLTGRAEALIQLLDVNDND--PVVKFRYF 358
Query: 384 TKVSYLIEVDEDVKEGSIIGQVTAYDPD--ARNNLIKYSVDRHTDMDRIFGIHSEN---- 437
S VDE+ + G+++ +T D D A N I + + R F + S
Sbjct: 359 PATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNE-QRHFEVQSSKVPNL 417
Query: 438 GSIFTLKALDRESSPWHNITVTATEINN-------PKQSSHIPVFIRILDINDHAPEFA- 489
I ALDRE P +N+TV+ ++ +SS + I + DINDH P F+
Sbjct: 418 SLIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQ 477
Query: 490 MYYETFVCENAKPGQLIQTVSVMDKD 515
Y + E A PG + +S D D
Sbjct: 478 QVYRVNLSEEAPPGSYVSGISATDGD 503
Score = 135 bits (341), Expect = 1e-31
Identities = 146/536 (27%), Positives = 229/536 (42%), Gaps = 49/536 (9%)
Query: 63 LEEYTGTDTQYVGKLHTDQDKG-DGNLKYILTGDGAGSLFVIDENTGDIHAAKKLDREEK 121
+ E T T T + D D+G +G ++Y + F ID TG I AK LDRE+
Sbjct: 2163 INENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKT 2222
Query: 122 SLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTKDLYTASVPEMSG-VGTSVIQ 180
Y L +A DR + + + + I+ + DIND P F Y+ +VPE G + +++Q
Sbjct: 2223 PTYHLTVQATDRGSTPRTDTSTVSIVLL-DINDFVPVFELSPYSVNVPENLGTLPRTILQ 2281
Query: 181 VTATDADDANYGNSAKVVYSILQGQP----YFSVDPESGIIKTALPDMSRENREQYQVVI 236
V A D D G+++K+ Y + G S E G+ ++ + RE +E++ ++I
Sbjct: 2282 VVARDDDR---GSNSKLSYVLFGGNEDNAFTLSASGELGVTQS----LDRETKERFVLMI 2334
Query: 237 QAKDMGGQMGGLSGTTTVNITLTDVNNNPPRFPQSTYQFNSPESVPLGTHLGRIKANDPD 296
A D G L+GT T+N+ + DVN+N P F Y PE P GT + + A+D D
Sbjct: 2335 TATDSGSP--ALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDAD 2392
Query: 297 VGENAEMEYSIAEGDGADMFDVITDKDTQEGIITVKQNLDFENQMLYTLRVDASNT-HPD 355
+NA + G F + + G I LD E + YTL V S+ P+
Sbjct: 2393 ASKNAVIRII----GGNSQFTI----NPSTGQIITSALLDRETKDNYTLVVVCSDAGSPE 2444
Query: 356 PRFLHLGPFKDTAVVKISVEDI-DEPPVFTKVSYLIEVDEDVKEGSIIGQVTAYDPD-AR 413
P + V ++V D+ D PP F Y+ + GS + VT D D
Sbjct: 2445 -------PLSSSTSVLVTVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGP 2497
Query: 414 NNLIKYSVDRHTDMDRIFGIHSENGSIFTLKALDRESSPWHNITVTATEINNPKQSSHIP 473
N+ + YS+ F I G+I L+ S ++ V + PK S
Sbjct: 2498 NSELHYSLSGRN--SEKFHIDPLRGAIMAAGPLNGASEVTFSVHVKDGG-SFPKTDS-TT 2553
Query: 474 VFIRILDINDHAPEFAMYYETFVC-ENAKPGQLIQTVSVMDKDDPPRGHKFFFEPVPEFT 532
V +R ++ D P+ +TF+ EN L+ T++ G EP+ +
Sbjct: 2554 VTVRFVNKADF-PKVRAKEQTFMFPENQPVSSLVTTIT---------GSSLRGEPMSYYI 2603
Query: 533 LNPNFTIVDNKDNTAGIMTRKDGYSRNKMSTYLLPILIFDNDYPIQSSTGTLTIRV 588
+ N D G ++ K+ Y++ I D +P SS L I V
Sbjct: 2604 ASGNLGNTFQIDQLTGQVSISQPLDFEKIQKYVVWIEARDGGFPPFSSYEKLDITV 2659
Score = 135 bits (341), Expect = 1e-31
Identities = 126/449 (28%), Positives = 210/449 (46%), Gaps = 31/449 (6%)
Query: 79 TDQDKG-DGNLKYILTGDGAGSLFVIDENTGDIHAAKKLDREE----KSLYILRAKAIDR 133
TD D+G +G + Y + F I+ TG+I + L + ++ I R I
Sbjct: 2897 TDPDEGSNGQVFYFIKSQS--EYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVT 2954
Query: 134 KTGR---QVEPESEFIIKIHDINDNEPKFTKDLYTASVPEMSGVGTSVIQVTATDADDAN 190
+ R + E+ I I D NDN P+F K Y V + VGT +I+VTA D D +
Sbjct: 2955 SSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAID--DKD 3012
Query: 191 YGNSAKVVYSILQGQPY--FSVDPESGIIKTALPDMSRENREQYQVVIQAKDMGGQMGGL 248
+G +++V Y I F +D ++G I A +S N + + + + AKD G L
Sbjct: 3013 FGLNSEVEYFISNDNHLGKFKLDNDTGWISVASSLISDLN-QNFFITVTAKDKGNPP--L 3069
Query: 249 SGTTTVNITLTDVNNNPPRFPQSTYQFNSPESVPLGTHLGRIKANDPDVGENAEMEYSIA 308
S TV+IT+T+ N + P F QS PES +G+ + + A D D N ++YSI+
Sbjct: 3070 SSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSIS 3129
Query: 309 EGDGADMFDVITDKDTQEGIITVKQNLDFENQMLYTLRVDASNTHPDPRFLHLGPFKDTA 368
G+ +F + ++ GI+T+ + LD+E + + + A + R +
Sbjct: 3130 SGNEEGIFAI----NSSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCS------ 3179
Query: 369 VVKISVEDI-DEPPVFTKVSYLIEVDEDVKEGSIIGQVTAYDPDARNNLIKYSVDRHTDM 427
V ++V D+ D PVF Y V E+ G+ + + A D D+ N + + +D
Sbjct: 3180 -VTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDS 3238
Query: 428 DRIFGIHSENGSIFTLKALDRESSPWHNITVTATEINNPKQSSHIPVFIRILDINDHAPE 487
D +F I G I T LD E+ +++TV A + + ++ S V I++ N++ P
Sbjct: 3239 D-LFVIDPNTGVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPR 3297
Query: 488 F-AMYYETFVCENAKPGQLIQTVSVMDKD 515
F + Y + E A G ++ V D+D
Sbjct: 3298 FVSKLYYFEISEAAPKGTIVGEVFASDRD 3326
Score = 91.7 bits (226), Expect = 2e-18
Identities = 101/405 (24%), Positives = 185/405 (45%), Gaps = 35/405 (8%)
Query: 79 TDQDKG-DGNLKYILTGDGAGSLFVIDENTGDIHAAKKLDREEKSLYILR--AKAIDRKT 135
+D+D G DG + Y++ G+ F I++ TG I+ + LDRE++ L+ AK
Sbjct: 3323 SDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKEERVSLKVLAKNFGSIR 3382
Query: 136 GRQVEPESEFIIKIHDINDNEPKFTKDLYTASVPEMSGVGTSVIQVTATDADDANYGNSA 195
G ++ E + + D ND P FT ++Y+ + E +GT V V+A D+D + + +
Sbjct: 3383 GADID-EVTVNVTVLDAND-PPIFTLNIYSVQISEGVPIGTHVTFVSAFDSD--SIPSWS 3438
Query: 196 KVVYSILQGQPY--FSVDPESGIIKTALPDMSRENREQYQVVIQAKDMGGQMGGLSGTTT 253
+ Y I G FS++P++G I T ++ RE Y + + A D G +G+ +
Sbjct: 3439 RFSYFIGSGNENGAFSINPQTGQI-TVTAELDRETLPIYNLSVLAVDSGTPSA--TGSAS 3495
Query: 254 VNITLTDVNNNPPRFPQSTYQFNSPESVPLGTHLGRIKANDPDVGENAE--MEYSIAEGD 311
+ +TL D+N+N P S + E+ GT + +++ DPD+ N Y ++ G
Sbjct: 3496 LLVTLEDINDNGPMLTVSEGEVM--ENKRPGTLVMTLQSTDPDLPPNQGPFTYYLLSTGP 3553
Query: 312 GADMFDVITDKDTQEGIITVKQNLDFENQMLYTLRVDASNTHPDPRFLHLGPFKDTAVVK 371
F + T G+++ + +D E + L V ++ + T V
Sbjct: 3554 ATSYFSLST-----AGVLSTTREIDREQIADFYLSVVTKDSG-------VPQMSSTGTVH 3601
Query: 372 ISVEDIDEPPVFTK-VSYLIEVDEDVKEGSIIGQVTAYDPDARNNLIKYSVDRHTDMDRI 430
I+V D ++ P ++ V + ++ G I+G V DPD L + + + +
Sbjct: 3602 ITVIDQNDNPSQSRTVEIFVNYYGNLFPGGILGSVKPQDPDV---LDSFHCSLTSGVTSL 3658
Query: 431 FGIHSENGSIFTLKALDRESSPWHNITVTATEINNPKQSSHIPVF 475
F I G L + R + ++TV + + + +S+I VF
Sbjct: 3659 FSI---PGGTCDLNSQPRSTDGTFDLTVLSNDGVHSTVTSNIRVF 3700
Score = 80.5 bits (197), Expect = 6e-15
Identities = 66/231 (28%), Positives = 100/231 (43%), Gaps = 8/231 (3%)
Query: 68 GTDTQYVGKLHTDQDKGDGNLKYILTGDGAGSLFVIDENTGDIHAAKKLDREEKSLYILR 127
GT +V +D Y + F I+ TG I +LDRE +Y L
Sbjct: 3420 GTHVTFVSAFDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLS 3479
Query: 128 AKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTKDLYTASVPEMSGVGTSVIQVTATDAD 187
A+D T + ++ + DINDN P T + V E GT V+ + +TD D
Sbjct: 3480 VLAVDSGT-PSATGSASLLVTLEDINDNGPMLT--VSEGEVMENKRPGTLVMTLQSTDPD 3536
Query: 188 -DANYGNSAKVVYSILQGQPYFSVDPESGIIKTALPDMSRENREQYQVVIQAKDMGGQMG 246
N G + S YFS+ +G++ T ++ RE + + + KD G +
Sbjct: 3537 LPPNQGPFTYYLLSTGPATSYFSLS-TAGVLSTT-REIDREQIADFYLSVVTKDSG--VP 3592
Query: 247 GLSGTTTVNITLTDVNNNPPRFPQSTYQFNSPESVPLGTHLGRIKANDPDV 297
+S T TV+IT+ D N+NP + N ++ G LG +K DPDV
Sbjct: 3593 QMSSTGTVHITVIDQNDNPSQSRTVEIFVNYYGNLFPGGILGSVKPQDPDV 3643
>gi|29570800 cadherin-like 26 isoform a [Homo sapiens]
Length = 832
Score = 194 bits (492), Expect = 3e-49
Identities = 178/685 (25%), Positives = 307/685 (44%), Gaps = 60/685 (8%)
Query: 9 LFIWTYMFHTVDTILLQEKPNSYLSSKKIAGLTKDDGKMLRRTKRGWMWNQFFLLEEYTG 68
L +W +D++ + + + +KI + LRR+KR W+ L EE G
Sbjct: 17 LLLWLLQVSIIDSVQQETDDLTKQTKEKIY-------QPLRRSKRRWVITTLELEEEDPG 69
Query: 69 TDTQYVGKLHTDQDKGDGNLKYILTGDGA------GSLFVIDENTGDIHAAKKLDREEKS 122
+ +G+L + + +L Y+++G G G + D G I+ + +DRE
Sbjct: 70 PFPKLIGELFNNMSY-NMSLMYLISGPGVDEYPEIGLFSLEDHENGRIYVHRPVDREMTP 128
Query: 123 LYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTKDLYTASVPEMSGVGTSVIQVT 182
+ + ++R TG+ V+ F I+I D+ND+ P+F + + +V E G + Q+
Sbjct: 129 SFTVYFDVVERSTGKIVDTSLIFNIRISDVNDHAPQFPEKEFNITVQENQSAGQPIFQML 188
Query: 183 ATDADDANYGNSAKVVYSILQGQPY-----FSVDPESGIIKTALPDMSRENREQYQVVIQ 237
A D D+ N NS +V+Y ++ P F VD SG I+ + + E Q+ ++I+
Sbjct: 189 AVDLDEENTPNS-QVLYFLISQTPLLKESGFRVDRLSGEIRLS-GCLDYETAPQFTLLIR 246
Query: 238 AKDMGGQMGGLSGTTTVNITLTDVNNNPPRFPQSTYQFNSPES-VPLGTHLGRIKANDPD 296
A+D G LS TTTV++ + + NN+ P F Q Y+ PE G ++ D
Sbjct: 247 ARDCGEP--SLSSTTTVHVDVQEGNNHRPAFTQENYKVQIPEGRASQGVLRLLVQDRDSP 304
Query: 297 VGENAEMEYSIAEGDGADMFDVITDKDTQEGIITVKQNLDFENQMLYTLRVDASNTHPDP 356
+++I G+ FD+ TD +T EGI+ V + LD+E + +L + N
Sbjct: 305 FTSAWRAKFNILHGNEEGHFDISTDPETNEGILNVIKPLDYETRPAQSLIIVVEN-EERL 363
Query: 357 RFLHLGPFKD------TAVVKISVEDIDEPPVFTKVSYLIEVDEDVKEGSIIGQVTAYDP 410
F G + +A V + V D ++PP F S+++ +E + G+++G A DP
Sbjct: 364 VFCERGKLQPPRKAAASATVSVQVTDANDPPAFHPQSFIVNKEEGARPGTLLGTFNAMDP 423
Query: 411 DARNNLIKYSVDRHTDMDRIFGIHSENGSIFTLKALDRESSPWHN----ITVTATEINNP 466
D++ I+Y + D + +G + T++ +DRES +N I + A + P
Sbjct: 424 DSQ---IRYELVH--DPANWVSVDKNSGVVITVEPIDRESPHVNNSFYVIIIHAVDDGFP 478
Query: 467 KQSSHIPVFIRILDINDHAPEF---AMYYETFVCENAKPGQLIQTVSVMDKDDPPRGHKF 523
Q++ + + + DIND+ P + Y E VCE+A L + D D P F
Sbjct: 479 PQTATGTLMLFLSDINDNVPTLRPRSRYME--VCESAVHEPL--HIEAEDPDLEPFSDPF 534
Query: 524 FFEPVPEF-TLNPNFTIVDNKDNTAGIMTRKDGYSRNKMSTYLLPILIFDNDYPIQSSTG 582
FE + + + N + ++T + N YL+P+ I D Q
Sbjct: 535 TFELDNTWGNAEDTWKLGRNWGQSVELLTLRSLPRGN----YLVPLFIGDKQGLSQKQ-- 588
Query: 583 TLTIRVCACDNQGNMQSCTAEALILSAGLSTGAL--VAILLCVLILLILVVLFAALKRQR 640
T+ +R+C C + +C E GL GAL V L + +L +L +
Sbjct: 589 TVHVRICPC---ASGLTC-VELADAEVGLHVGALFPVCAAFVALAVALLFLLRCYFVLEP 644
Query: 641 KKEPLIISKDDVRDNIVTYNDEGGG 665
K+ +S D+ +V YN E G
Sbjct: 645 KRHGCSVSNDEGHQTLVMYNAESKG 669
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.135 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,505,053
Number of Sequences: 37866
Number of extensions: 1419548
Number of successful extensions: 8154
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 195
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 3095
Number of HSP's gapped (non-prelim): 899
length of query: 789
length of database: 18,247,518
effective HSP length: 110
effective length of query: 679
effective length of database: 14,082,258
effective search space: 9561853182
effective search space used: 9561853182
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.