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Search of human proteins with 89886237
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|89886237 cyclin I family, member 2 [Homo sapiens]
(369 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|89886237 cyclin I family, member 2 [Homo sapiens] 745 0.0
gi|5802992 cyclin I [Homo sapiens] 196 2e-50
gi|4757936 cyclin G2 [Homo sapiens] 89 6e-18
gi|40805832 cyclin G1 [Homo sapiens] 84 2e-16
gi|4757934 cyclin G1 [Homo sapiens] 84 2e-16
gi|17318565 cyclin E2 [Homo sapiens] 59 9e-09
gi|4757930 cyclin B2 [Homo sapiens] 53 4e-07
gi|17318559 cyclin E1 isoform 1 [Homo sapiens] 51 2e-06
gi|17318561 cyclin E1 isoform 2 [Homo sapiens] 51 2e-06
gi|14327896 cyclin B1 [Homo sapiens] 50 2e-06
gi|4502617 cyclin D2 [Homo sapiens] 50 2e-06
gi|4502613 cyclin A [Homo sapiens] 49 7e-06
gi|90669307 cyclin B3 isoform 3 [Homo sapiens] 49 9e-06
gi|16950655 cyclin D1 [Homo sapiens] 48 2e-05
gi|161377472 cyclin A1 isoform c [Homo sapiens] 45 1e-04
gi|161377470 cyclin A1 isoform c [Homo sapiens] 45 1e-04
gi|161377468 cyclin A1 isoform b [Homo sapiens] 45 1e-04
gi|4502611 cyclin A1 isoform a [Homo sapiens] 45 1e-04
gi|239754748 PREDICTED: hypothetical protein [Homo sapiens] 44 2e-04
gi|48476182 roundabout, axon guidance receptor, homolog 3 [Homo ... 44 2e-04
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 43 4e-04
gi|4502619 cyclin D3 isoform 2 [Homo sapiens] 43 5e-04
gi|154146199 sal-like 3 [Homo sapiens] 43 5e-04
gi|197276676 cyclin J isoform 3 [Homo sapiens] 43 5e-04
gi|197276674 cyclin J isoform 1 [Homo sapiens] 43 5e-04
gi|40254889 cyclin J isoform 2 [Homo sapiens] 43 5e-04
gi|12751477 forkhead box L2 [Homo sapiens] 42 7e-04
gi|39812378 RAN binding protein 9 [Homo sapiens] 42 9e-04
gi|110832843 TBP-associated factor 4 [Homo sapiens] 42 9e-04
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 42 9e-04
>gi|89886237 cyclin I family, member 2 [Homo sapiens]
Length = 369
Score = 745 bits (1924), Expect = 0.0
Identities = 369/369 (100%), Positives = 369/369 (100%)
Query: 1 MASGAQLPPQPSSSEVSAVQSPGGRPGAGLEETALGVPLPPSPGEAPLPRSNRSRCPGTR 60
MASGAQLPPQPSSSEVSAVQSPGGRPGAGLEETALGVPLPPSPGEAPLPRSNRSRCPGTR
Sbjct: 1 MASGAQLPPQPSSSEVSAVQSPGGRPGAGLEETALGVPLPPSPGEAPLPRSNRSRCPGTR 60
Query: 61 QPGAASLHAASAAVPVRPRRGTAPAGKTADAVPAAAPEQAPRPAPQSRKPRNLEGDLDER 120
QPGAASLHAASAAVPVRPRRGTAPAGKTADAVPAAAPEQAPRPAPQSRKPRNLEGDLDER
Sbjct: 61 QPGAASLHAASAAVPVRPRRGTAPAGKTADAVPAAAPEQAPRPAPQSRKPRNLEGDLDER 120
Query: 121 RLLCHLQLAQDREARLWRGGKPQDEICDAFEEVVLWLLRLQNTFYFSQSTFNLALTIFGR 180
RLLCHLQLAQDREARLWRGGKPQDEICDAFEEVVLWLLRLQNTFYFSQSTFNLALTIFGR
Sbjct: 121 RLLCHLQLAQDREARLWRGGKPQDEICDAFEEVVLWLLRLQNTFYFSQSTFNLALTIFGR 180
Query: 181 LLISVKVKEKYLHCATITSLRLAAKVNEEEEFIPQVKDFTKHYGSDYSPNELLRMELAIL 240
LLISVKVKEKYLHCATITSLRLAAKVNEEEEFIPQVKDFTKHYGSDYSPNELLRMELAIL
Sbjct: 181 LLISVKVKEKYLHCATITSLRLAAKVNEEEEFIPQVKDFTKHYGSDYSPNELLRMELAIL 240
Query: 241 DRLHWDLYIGTPLDFLTIFHALVVLSWPHVLELLPQRNPSLHVASLTRQLQHCMAGHQLL 300
DRLHWDLYIGTPLDFLTIFHALVVLSWPHVLELLPQRNPSLHVASLTRQLQHCMAGHQLL
Sbjct: 241 DRLHWDLYIGTPLDFLTIFHALVVLSWPHVLELLPQRNPSLHVASLTRQLQHCMAGHQLL 300
Query: 301 QFKGSTLALVIITLELERLMPGWCAPISDLLKKAQVGDMQYSCCKELVMQQLRSLQSSSC 360
QFKGSTLALVIITLELERLMPGWCAPISDLLKKAQVGDMQYSCCKELVMQQLRSLQSSSC
Sbjct: 301 QFKGSTLALVIITLELERLMPGWCAPISDLLKKAQVGDMQYSCCKELVMQQLRSLQSSSC 360
Query: 361 TDNFVSPAN 369
TDNFVSPAN
Sbjct: 361 TDNFVSPAN 369
>gi|5802992 cyclin I [Homo sapiens]
Length = 377
Score = 196 bits (499), Expect = 2e-50
Identities = 111/249 (44%), Positives = 155/249 (62%), Gaps = 5/249 (2%)
Query: 115 GDLDERRLLCHLQLAQDREARLWRGG-----KPQDEICDAFEEVVLWLLRLQNTFYFSQS 169
G L+ +RL L+ A REA++W+ Q+ +EV+ WL +L+ F
Sbjct: 5 GPLENQRLSFLLEKAITREAQMWKVNVRKMPSNQNVSPSQRDEVIQWLAKLKYQFNLYPE 64
Query: 170 TFNLALTIFGRLLISVKVKEKYLHCATITSLRLAAKVNEEEEFIPQVKDFTKHYGSDYSP 229
TF LA ++ R L +VK KYL C I+ LAAK EE+E IP +K + S
Sbjct: 65 TFALASSLLDRFLATVKAHPKYLSCIAISCFFLAAKTVEEDERIPVLKVLARDSFCGCSS 124
Query: 230 NELLRMELAILDRLHWDLYIGTPLDFLTIFHALVVLSWPHVLELLPQRNPSLHVASLTRQ 289
+E+LRME ILD+L+WDL+ TPLDFL IFHA+ V + P +L LP+ +PS H+A LT+Q
Sbjct: 125 SEILRMERIILDKLNWDLHTATPLDFLHIFHAIAVSTRPQLLFSLPKLSPSQHLAVLTKQ 184
Query: 290 LQHCMAGHQLLQFKGSTLALVIITLELERLMPGWCAPISDLLKKAQVGDMQYSCCKELVM 349
L HCMA +QLLQF+GS LAL +++LE+E+L+P W + +LL+KAQ+ Q C+ELV
Sbjct: 185 LLHCMACNQLLQFRGSMLALAMVSLEMEKLIPDWLSLTIELLQKAQMDSSQLIHCRELVA 244
Query: 350 QQLRSLQSS 358
L +LQSS
Sbjct: 245 HHLSTLQSS 253
>gi|4757936 cyclin G2 [Homo sapiens]
Length = 344
Score = 89.0 bits (219), Expect = 6e-18
Identities = 66/205 (32%), Positives = 102/205 (49%), Gaps = 8/205 (3%)
Query: 157 LLRLQNTFYFSQSTFNLALTIFGRLLISVKVKEKYLHCATITSLRLAAKVNEEEEFIPQV 216
L L N F TF LA+ I R L +KVK K+L C + S LAA++ EE+ IP
Sbjct: 63 LRSLANFFGSCTETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARIVEEDCNIPST 122
Query: 217 KDFTKHYGSDYSPNELLRMELAILDRLHWDLYIGTPLDFLTIFHALVVLSWPHVLELLPQ 276
D + + +++ RME I ++LH++L T L+FL ++H +++ H E
Sbjct: 123 HDVIRISQCKCTASDIKRMEKIISEKLHYELEATTALNFLHLYHTIILC---HTSE---- 175
Query: 277 RNPSLHVASLTRQLQHCMAGHQLLQFKGSTLALVIITLELERLMPGWCAPISDLLKK-AQ 335
R L + L QL+ C + K S LAL ++ LE+E L I L+KK ++
Sbjct: 176 RKEILSLDKLEAQLKACNCRLIFSKAKPSVLALCLLNLEVETLKSVELLEILLLVKKHSK 235
Query: 336 VGDMQYSCCKELVMQQLRSLQSSSC 360
+ D ++ +ELV + L S C
Sbjct: 236 INDTEFFYWRELVSKCLAEYSSPEC 260
>gi|40805832 cyclin G1 [Homo sapiens]
Length = 295
Score = 84.3 bits (207), Expect = 2e-16
Identities = 61/209 (29%), Positives = 105/209 (50%), Gaps = 13/209 (6%)
Query: 157 LLRLQNTFYFSQSTFNLALTIFGRLLISVKVKEKYLHCATITSLRLAAKVNEEEEFIPQV 216
LL L F F TF+LA+ + R L +KV+ K+L C ++ LA K EEE +P
Sbjct: 59 LLSLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLA 118
Query: 217 KDFTKHYGSDYSPNELLRMELAILDRLHWDLYIGTPLDFLTIFHALVVLSWPHVLELLPQ 276
D + ++ ++L+RME +L+++ W + T FL ++++L+ + P L +
Sbjct: 119 TDLIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLP-----LER 173
Query: 277 RNPSLHVASLTRQLQHCMAGHQLLQFKGSTLALVIITLELERLMPGWCAPISD----LLK 332
RN S++ L QL+ C + K S LAL II LE++ C +++ L K
Sbjct: 174 RN-SINFERLEAQLKACHCRIIFSKAKPSVLALSIIALEIQAQK---CVELTEGIECLQK 229
Query: 333 KAQVGDMQYSCCKELVMQQLRSLQSSSCT 361
+++ + +ELV + L S+ C+
Sbjct: 230 HSKINGRDLTFWQELVSKCLTEYSSNKCS 258
>gi|4757934 cyclin G1 [Homo sapiens]
Length = 295
Score = 84.3 bits (207), Expect = 2e-16
Identities = 61/209 (29%), Positives = 105/209 (50%), Gaps = 13/209 (6%)
Query: 157 LLRLQNTFYFSQSTFNLALTIFGRLLISVKVKEKYLHCATITSLRLAAKVNEEEEFIPQV 216
LL L F F TF+LA+ + R L +KV+ K+L C ++ LA K EEE +P
Sbjct: 59 LLSLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLA 118
Query: 217 KDFTKHYGSDYSPNELLRMELAILDRLHWDLYIGTPLDFLTIFHALVVLSWPHVLELLPQ 276
D + ++ ++L+RME +L+++ W + T FL ++++L+ + P L +
Sbjct: 119 TDLIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLP-----LER 173
Query: 277 RNPSLHVASLTRQLQHCMAGHQLLQFKGSTLALVIITLELERLMPGWCAPISD----LLK 332
RN S++ L QL+ C + K S LAL II LE++ C +++ L K
Sbjct: 174 RN-SINFERLEAQLKACHCRIIFSKAKPSVLALSIIALEIQAQK---CVELTEGIECLQK 229
Query: 333 KAQVGDMQYSCCKELVMQQLRSLQSSSCT 361
+++ + +ELV + L S+ C+
Sbjct: 230 HSKINGRDLTFWQELVSKCLTEYSSNKCS 258
>gi|17318565 cyclin E2 [Homo sapiens]
Length = 404
Score = 58.5 bits (140), Expect = 9e-09
Identities = 46/150 (30%), Positives = 76/150 (50%), Gaps = 7/150 (4%)
Query: 156 WLLRLQNTFYFSQSTFNLALTIFGRLLISVK-VKEKYLHCATITSLRLAAKVNEEEEFIP 214
WLL + + + TF LA F R +++ K + + L ITSL +A+K+ EE + P
Sbjct: 148 WLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSLFIASKL--EEIYAP 205
Query: 215 QVKDFTKHYGSDYSPNELLRMELAILDRLHWDLYIGTPLDFLTIFHALVVL-SWPHVLEL 273
++++F S ++LRMEL IL L W+L T + +L +F + L P V L
Sbjct: 206 KLQEFAYVTDGACSEEDILRMELIILKALKWELCPVTIISWLNLFLQVDALKDAPKV--L 263
Query: 274 LPQRNPSLHVASLTRQLQHCMAGHQLLQFK 303
LPQ + + + + L C+ L+F+
Sbjct: 264 LPQYSQETFI-QIAQLLDLCILAIDSLEFQ 292
>gi|4757930 cyclin B2 [Homo sapiens]
Length = 398
Score = 53.1 bits (126), Expect = 4e-07
Identities = 35/104 (33%), Positives = 53/104 (50%), Gaps = 2/104 (1%)
Query: 153 VVLWLLRLQNTFYFSQSTFNLALTIFGRLLISVKVKEKYLHCATITSLRLAAKVNEEEEF 212
+V WL+++ + F Q T + + I R L V K L IT+L LA+K EE F
Sbjct: 169 LVDWLVQVHSKFRLLQETLYMCVGIMDRFLQVQPVSRKKLQLVGITALLLASKY--EEMF 226
Query: 213 IPQVKDFTKHYGSDYSPNELLRMELAILDRLHWDLYIGTPLDFL 256
P ++DF + Y+ +++ ME IL L ++L PL FL
Sbjct: 227 SPNIEDFVYITDNAYTSSQIREMETLILKELKFELGRPLPLHFL 270
>gi|17318559 cyclin E1 isoform 1 [Homo sapiens]
Length = 410
Score = 50.8 bits (120), Expect = 2e-06
Identities = 49/176 (27%), Positives = 82/176 (46%), Gaps = 11/176 (6%)
Query: 156 WLLRLQNTFYFSQSTFNLALTIFGRLLISVK-VKEKYLHCATITSLRLAAKVNEEEEFIP 214
WL+ + + + TF LA F R + + + V + L I+SL +AAK+ EE + P
Sbjct: 151 WLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKL--EEIYPP 208
Query: 215 QVKDFTKHYGSDYSPNELLRMELAILDRLHWDLYIGTPLDFLTIFHALVVLSWPHVLELL 274
++ F S +E+L MEL I+ L W L T + +L ++ + L+ H + LL
Sbjct: 209 KLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEV-LL 267
Query: 275 PQRNPSLHVASLTRQLQHCMAGHQLLQFKGSTLALVII----TLELERLMPG--WC 324
PQ + + + L C+ L+F LA + + EL + + G WC
Sbjct: 268 PQYPQQIFI-QIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWC 322
>gi|17318561 cyclin E1 isoform 2 [Homo sapiens]
Length = 395
Score = 50.8 bits (120), Expect = 2e-06
Identities = 49/176 (27%), Positives = 82/176 (46%), Gaps = 11/176 (6%)
Query: 156 WLLRLQNTFYFSQSTFNLALTIFGRLLISVK-VKEKYLHCATITSLRLAAKVNEEEEFIP 214
WL+ + + + TF LA F R + + + V + L I+SL +AAK+ EE + P
Sbjct: 136 WLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKL--EEIYPP 193
Query: 215 QVKDFTKHYGSDYSPNELLRMELAILDRLHWDLYIGTPLDFLTIFHALVVLSWPHVLELL 274
++ F S +E+L MEL I+ L W L T + +L ++ + L+ H + LL
Sbjct: 194 KLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEV-LL 252
Query: 275 PQRNPSLHVASLTRQLQHCMAGHQLLQFKGSTLALVII----TLELERLMPG--WC 324
PQ + + + L C+ L+F LA + + EL + + G WC
Sbjct: 253 PQYPQQIFI-QIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWC 307
>gi|14327896 cyclin B1 [Homo sapiens]
Length = 433
Score = 50.4 bits (119), Expect = 2e-06
Identities = 30/101 (29%), Positives = 56/101 (55%), Gaps = 2/101 (1%)
Query: 156 WLLRLQNTFYFSQSTFNLALTIFGRLLISVKVKEKYLHCATITSLRLAAKVNEEEEFIPQ 215
WL+++Q F Q T + ++I R + + V +K L +T++ +A+K EE + P+
Sbjct: 208 WLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFIASKY--EEMYPPE 265
Query: 216 VKDFTKHYGSDYSPNELLRMELAILDRLHWDLYIGTPLDFL 256
+ DF + Y+ +++ +ME+ IL L++ L PL FL
Sbjct: 266 IGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRPLPLHFL 306
>gi|4502617 cyclin D2 [Homo sapiens]
Length = 289
Score = 50.4 bits (119), Expect = 2e-06
Identities = 50/214 (23%), Positives = 83/214 (38%), Gaps = 23/214 (10%)
Query: 153 VVLWLLRLQNTFYFSQSTFNLALTIFGRLLISVKVKEKYLHCATITSLRLAAKVNEEEEF 212
V W+L + + F LA+ R L V + +L + LA+K+ E
Sbjct: 59 VATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPL 118
Query: 213 IPQVKDFTKHYGSDYSPNELLRMELAILDRLHWDLYIGTPLDFLTIFHALVVLSWPHVLE 272
+ + + P ELL EL +L +L W+L TP DF+ H+L
Sbjct: 119 TAE--KLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFI-----------EHILR 165
Query: 273 LLPQRNPSLHVASLTRQ--LQHCMAGHQLLQF------KGSTLALVIITLELERLMPGWC 324
LPQ+ L + Q + C + + GS A + + E + C
Sbjct: 166 KLPQQREKLSLIRKHAQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTC 225
Query: 325 APISDLLKKAQVGDMQ--YSCCKELVMQQLRSLQ 356
+++LL K D+ +C +++ L SLQ
Sbjct: 226 DALTELLAKITNTDVDCLKACQEQIEAVLLNSLQ 259
>gi|4502613 cyclin A [Homo sapiens]
Length = 432
Score = 48.9 bits (115), Expect = 7e-06
Identities = 34/118 (28%), Positives = 57/118 (48%), Gaps = 3/118 (2%)
Query: 141 KPQDEICDAFEEVVL-WLLRLQNTFYFSQSTFNLALTIFGRLLISVKVKEKYLHCATITS 199
K Q +I ++ +++ WL+ + + T +LA+ R L S+ V L +
Sbjct: 201 KKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAA 260
Query: 200 LRLAAKVNEEEEFIPQVKDFTKHYGSDYSPNELLRMELAILDRLHWDLYIGTPLDFLT 257
+ LA+K EE + P+V +F Y+ ++LRME +L L +DL T FLT
Sbjct: 261 MLLASKF--EEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLT 316
>gi|90669307 cyclin B3 isoform 3 [Homo sapiens]
Length = 1395
Score = 48.5 bits (114), Expect = 9e-06
Identities = 45/174 (25%), Positives = 73/174 (41%), Gaps = 15/174 (8%)
Query: 153 VVLWLLRLQNTFYFSQSTFNLALTIFGRLLISVKVKEKYLHCATITSLRLAAKVNEEEEF 212
+V WL+ +Q +F + T LA+ + L+ K+ L T+ +AAK E
Sbjct: 1164 LVDWLVEVQVSFEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNS- 1222
Query: 213 IPQVKDFTKHYGSDYSPNELLRMELAILDRLHWDLYIGTPLDFLTIFHALVVLSWPHVLE 272
P+V DF +Y +E+L ME+ IL+ L D+ I FL + + +
Sbjct: 1223 -PRVDDFVYICDDNYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTN------ 1275
Query: 273 LLPQRNPSLHVASLTRQLQHCMAGHQLLQFKGSTLALVIITLELERLMPGWCAP 326
+ S ++ +T Q H +Q K S LA + L L G+ P
Sbjct: 1276 -MKTLTLSRYICEMTLQEYH------YVQEKASKLAAASLLLALYMKKLGYWVP 1322
>gi|16950655 cyclin D1 [Homo sapiens]
Length = 295
Score = 47.8 bits (112), Expect = 2e-05
Identities = 35/119 (29%), Positives = 57/119 (47%), Gaps = 5/119 (4%)
Query: 143 QDEICDAFEEVVL-WLLRLQNTFYFSQSTFNLALTIFGRLLISVKVKEKYLHCATITSLR 201
Q E+ + ++V W+L + + F LA+ R L VK+ L T +
Sbjct: 49 QKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMF 108
Query: 202 LAAKVNEEEEFIPQVKDFTKHY-GSDYSPNELLRMELAILDRLHWDLYIGTPLDFLTIF 259
+A+K+ E IP + Y + P ELL+MEL ++++L W+L TP DF+ F
Sbjct: 109 VASKMKET---IPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHF 164
>gi|161377472 cyclin A1 isoform c [Homo sapiens]
Length = 421
Score = 45.1 bits (105), Expect = 1e-04
Identities = 32/117 (27%), Positives = 54/117 (46%), Gaps = 3/117 (2%)
Query: 141 KPQDEICDAFEEVVL-WLLRLQNTFYFSQSTFNLALTIFGRLLISVKVKEKYLHCATITS 199
K Q +I + +++ WL+ + + T LA+ R L + V L +
Sbjct: 190 KKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAA 249
Query: 200 LRLAAKVNEEEEFIPQVKDFTKHYGSDYSPNELLRMELAILDRLHWDLYIGTPLDFL 256
+ LA+K EE + P+V +F Y+ +LL+ME +L L +DL + T FL
Sbjct: 250 MLLASKY--EEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFL 304
>gi|161377470 cyclin A1 isoform c [Homo sapiens]
Length = 421
Score = 45.1 bits (105), Expect = 1e-04
Identities = 32/117 (27%), Positives = 54/117 (46%), Gaps = 3/117 (2%)
Query: 141 KPQDEICDAFEEVVL-WLLRLQNTFYFSQSTFNLALTIFGRLLISVKVKEKYLHCATITS 199
K Q +I + +++ WL+ + + T LA+ R L + V L +
Sbjct: 190 KKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAA 249
Query: 200 LRLAAKVNEEEEFIPQVKDFTKHYGSDYSPNELLRMELAILDRLHWDLYIGTPLDFL 256
+ LA+K EE + P+V +F Y+ +LL+ME +L L +DL + T FL
Sbjct: 250 MLLASKY--EEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFL 304
>gi|161377468 cyclin A1 isoform b [Homo sapiens]
Length = 464
Score = 45.1 bits (105), Expect = 1e-04
Identities = 32/117 (27%), Positives = 54/117 (46%), Gaps = 3/117 (2%)
Query: 141 KPQDEICDAFEEVVL-WLLRLQNTFYFSQSTFNLALTIFGRLLISVKVKEKYLHCATITS 199
K Q +I + +++ WL+ + + T LA+ R L + V L +
Sbjct: 233 KKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAA 292
Query: 200 LRLAAKVNEEEEFIPQVKDFTKHYGSDYSPNELLRMELAILDRLHWDLYIGTPLDFL 256
+ LA+K EE + P+V +F Y+ +LL+ME +L L +DL + T FL
Sbjct: 293 MLLASKY--EEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFL 347
>gi|4502611 cyclin A1 isoform a [Homo sapiens]
Length = 465
Score = 45.1 bits (105), Expect = 1e-04
Identities = 32/117 (27%), Positives = 54/117 (46%), Gaps = 3/117 (2%)
Query: 141 KPQDEICDAFEEVVL-WLLRLQNTFYFSQSTFNLALTIFGRLLISVKVKEKYLHCATITS 199
K Q +I + +++ WL+ + + T LA+ R L + V L +
Sbjct: 234 KKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAA 293
Query: 200 LRLAAKVNEEEEFIPQVKDFTKHYGSDYSPNELLRMELAILDRLHWDLYIGTPLDFL 256
+ LA+K EE + P+V +F Y+ +LL+ME +L L +DL + T FL
Sbjct: 294 MLLASKY--EEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFL 348
>gi|239754748 PREDICTED: hypothetical protein [Homo sapiens]
Length = 229
Score = 43.9 bits (102), Expect = 2e-04
Identities = 28/70 (40%), Positives = 36/70 (51%), Gaps = 2/70 (2%)
Query: 38 PLPPSPGEAPLPRSNRSRCPGTRQPGA-ASLHAASAAVPVRPRRGTAPAGKTADAVPAAA 96
P PS G +PRS+R P +R+PG A H A +A RPR+ TA +PA
Sbjct: 105 PRSPSTGPDRVPRSSRRLPPESRRPGGPAKTHPARSAC-CRPRKSGRWPQSTARGLPAKT 163
Query: 97 PEQAPRPAPQ 106
+ P PAPQ
Sbjct: 164 RPKPPAPAPQ 173
>gi|48476182 roundabout, axon guidance receptor, homolog 3 [Homo
sapiens]
Length = 1386
Score = 43.9 bits (102), Expect = 2e-04
Identities = 34/113 (30%), Positives = 46/113 (40%), Gaps = 17/113 (15%)
Query: 8 PPQPSSSEVSAVQSPGG-------------RPGAGLEETALGVPLPPSPGEAPLPRSNRS 54
PP P S ++ S GG P G + TA P PP P + P +
Sbjct: 1115 PPMPERSHLTEPSSSGGCLVTPSRRETPSPTPSYGQQSTATLTPSPPDPPQPPTDMPHLH 1174
Query: 55 RCPGTRQPGAASLHAASAAVPVRPRRGTAPAGKTADAVPAAAPEQAPRPAPQS 107
+ P G +S S + P+ R PAG A PAA+P +P PAP +
Sbjct: 1175 QMPRRVPLGPSS--PLSVSQPMLGIREARPAG--LGAGPAASPHLSPSPAPST 1223
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 43.1 bits (100), Expect = 4e-04
Identities = 37/118 (31%), Positives = 49/118 (41%), Gaps = 24/118 (20%)
Query: 8 PPQPSSSEVSAVQSPGGRPGAGLEETALGVPLPPSPGEAPLP-------RSNRSRC---- 56
PP+ ++ + ++P G P A P PP P P P R+ R+
Sbjct: 101 PPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPP---PAPVAAAAPARAPRAAAAAAT 157
Query: 57 ----PGTRQPGAASLHAASAAVPVRPRRGTAPAGKTADAVPAAAPEQAPRPAPQSRKP 110
PG QPG + AA A P APA A A P A P +AP PA +R+P
Sbjct: 158 APPSPGPAQPGPRAQRAAPLAAP-----PPAPAAPPAVA-PPAGPRRAPPPAVAAREP 209
Score = 42.0 bits (97), Expect = 9e-04
Identities = 36/110 (32%), Positives = 43/110 (39%), Gaps = 5/110 (4%)
Query: 2 ASGAQLPPQPSSSEVSAVQSPGGRPGAGLEETALGVPLPPSPGEA-PLPRSNRSRCPGTR 60
A+ A PP P+ A + P A PPSPG A P PR+ R+
Sbjct: 122 AAAAAPPPTPAPPPPPAPVAAAA-PARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAP 180
Query: 61 QPGAASLHAASAAVPVRPRRGTAPAGKTADAVPAAAPEQAPRPAPQSRKP 110
P A+ A A P PRR PA A P P Q P P Q + P
Sbjct: 181 PPAPAAPPAV--APPAGPRRAPPPA-VAAREPPLPPPPQPPAPPQQQQPP 227
Score = 30.4 bits (67), Expect = 2.6
Identities = 25/70 (35%), Positives = 27/70 (38%), Gaps = 8/70 (11%)
Query: 49 PRSNRSRCPGTRQPGAASLHAASAAVPVRPRRGTAPAGKTADAVPAAAPEQA-------P 101
PR + R P A AA+AA P P PA A A PA AP A P
Sbjct: 102 PRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPA-PVAAAAPARAPRAAAAAATAPP 160
Query: 102 RPAPQSRKPR 111
P P PR
Sbjct: 161 SPGPAQPGPR 170
>gi|4502619 cyclin D3 isoform 2 [Homo sapiens]
Length = 292
Score = 42.7 bits (99), Expect = 5e-04
Identities = 70/276 (25%), Positives = 112/276 (40%), Gaps = 28/276 (10%)
Query: 100 APRPAPQSRKPRNLEGDLDERRLLCHLQLAQDREARLWRGGKPQDEICDAFEEVVL-WLL 158
APR P R L GD +R L L+L + R Q EI +++ W+L
Sbjct: 12 APRAGPDPR----LLGD--QRVLQSLLRLEERYVPRASYFQCVQREIKPHMRKMLAYWML 65
Query: 159 RLQNTFYFSQSTFNLALTIFGRLLISVKVKEKYLHCATITSLRLAAKVNEEEEF-IPQVK 217
+ + F LA+ R L V ++ L + LA+K+ E I ++
Sbjct: 66 EVCEEQRCEEEVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLC 125
Query: 218 DFTKHYGSDYSPNELLRMELAILDRLHWDLYIGTPLDFLTIFHALVVLSWPHVLELLPQR 277
+T H SP +L E+ +L +L WDL DFL L LS P + L ++
Sbjct: 126 IYTDHA---VSPRQLRDWEVLVLGKLKWDLAAVIAHDFLAFI--LHRLSLPRDRQALVKK 180
Query: 278 NPSLHVASLTRQLQHCMAGHQLLQFKGSTLALVIITLELERLMPGWCAPISDLLKK--AQ 335
+ +A C + + S +A I ++ L G C+ D L + A
Sbjct: 181 HAQTFLAL-------CATDYTFAMYPPSMIATGSIGAAVQGL--GACSMSGDELTELLAG 231
Query: 336 VGDMQYSC---CKELVMQQLR-SLQSSSCTDNFVSP 367
+ + C C+E + LR SL+ +S T + +P
Sbjct: 232 ITGTEVDCLRACQEQIEAALRESLREASQTSSSPAP 267
>gi|154146199 sal-like 3 [Homo sapiens]
Length = 1300
Score = 42.7 bits (99), Expect = 5e-04
Identities = 33/104 (31%), Positives = 42/104 (40%), Gaps = 14/104 (13%)
Query: 8 PPQPSSSEVSAVQSPGGRPGAGLEETALGVPLPPSPGEAPLPRSNRSRCPGTRQPGAASL 67
PP+PS S +A +PG P PG A LP S + G A+
Sbjct: 237 PPRPSLSPAAAPSAPGPAPSQ-------------LPGLAALPLSAGAPAAAIAGSGPAAP 283
Query: 68 HAASAAVPV-RPRRGTAPAGKTADAVPAAAPEQAPRPAPQSRKP 110
A A P+ RP G + G A+ AAP AP PA + P
Sbjct: 284 AAFEGAQPLSRPESGASTPGGPAEPSAPAAPSAAPAPAAPAPAP 327
Score = 30.8 bits (68), Expect = 2.0
Identities = 21/63 (33%), Positives = 25/63 (39%), Gaps = 5/63 (7%)
Query: 10 QPSSSEVSAVQSPGGRPGAGLEETALGVPLPPSPGEAPLPRSNRSRCPGTRQPGAASLHA 69
QP S S +PGG P P +P AP P+S S QP +AS
Sbjct: 290 QPLSRPESGASTPGGPAEPSAPAAPSAAPAPAAPAPAPAPQSAAS-----SQPQSASTPP 344
Query: 70 ASA 72
A A
Sbjct: 345 ALA 347
>gi|197276676 cyclin J isoform 3 [Homo sapiens]
Length = 371
Score = 42.7 bits (99), Expect = 5e-04
Identities = 28/128 (21%), Positives = 58/128 (45%), Gaps = 8/128 (6%)
Query: 137 WRGGKPQDEICDAFEEVVLWLLRLQNTFYFSQSTFNLALTIFGRLLISVKVKEKYLHCAT 196
++G PQ + F +++ + N F S +LA+ + + + + LH
Sbjct: 30 YKGQSPQLSLRRYFADLIAIV---SNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLVA 86
Query: 197 ITSLRLAAKVNEEEEFIPQVKDFTK-----HYGSDYSPNELLRMELAILDRLHWDLYIGT 251
++ L LA+K E+E+ +P+++ + + LL MEL +L+ W+L + T
Sbjct: 87 LSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELLLLETFQWNLCLPT 146
Query: 252 PLDFLTIF 259
F+ +
Sbjct: 147 AAHFIEYY 154
>gi|197276674 cyclin J isoform 1 [Homo sapiens]
Length = 383
Score = 42.7 bits (99), Expect = 5e-04
Identities = 28/128 (21%), Positives = 58/128 (45%), Gaps = 8/128 (6%)
Query: 137 WRGGKPQDEICDAFEEVVLWLLRLQNTFYFSQSTFNLALTIFGRLLISVKVKEKYLHCAT 196
++G PQ + F +++ + N F S +LA+ + + + + LH
Sbjct: 30 YKGQSPQLSLRRYFADLIAIV---SNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLVA 86
Query: 197 ITSLRLAAKVNEEEEFIPQVKDFTK-----HYGSDYSPNELLRMELAILDRLHWDLYIGT 251
++ L LA+K E+E+ +P+++ + + LL MEL +L+ W+L + T
Sbjct: 87 LSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELLLLETFQWNLCLPT 146
Query: 252 PLDFLTIF 259
F+ +
Sbjct: 147 AAHFIEYY 154
>gi|40254889 cyclin J isoform 2 [Homo sapiens]
Length = 372
Score = 42.7 bits (99), Expect = 5e-04
Identities = 28/128 (21%), Positives = 58/128 (45%), Gaps = 8/128 (6%)
Query: 137 WRGGKPQDEICDAFEEVVLWLLRLQNTFYFSQSTFNLALTIFGRLLISVKVKEKYLHCAT 196
++G PQ + F +++ + N F S +LA+ + + + + LH
Sbjct: 30 YKGQSPQLSLRRYFADLIAIV---SNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLVA 86
Query: 197 ITSLRLAAKVNEEEEFIPQVKDFTK-----HYGSDYSPNELLRMELAILDRLHWDLYIGT 251
++ L LA+K E+E+ +P+++ + + LL MEL +L+ W+L + T
Sbjct: 87 LSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELLLLETFQWNLCLPT 146
Query: 252 PLDFLTIF 259
F+ +
Sbjct: 147 AAHFIEYY 154
>gi|12751477 forkhead box L2 [Homo sapiens]
Length = 376
Score = 42.4 bits (98), Expect = 7e-04
Identities = 34/97 (35%), Positives = 40/97 (41%), Gaps = 12/97 (12%)
Query: 9 PQPSSSEVSAVQSPGGRPGAGLEETALGVPLPPSPGEAPLPRSNRSRCPGTRQPGAASLH 68
P S + VQS PG LG P P +P P P + P A LH
Sbjct: 251 PAASYGPYTRVQSMALPPGVVNSYNGLGGP-PAAPPPPPHPHPH---------PHAHHLH 300
Query: 69 AASAAVPVRPRRGTA--PAGKTADAVPAAAPEQAPRP 103
AA+A P P G A P G+ + A PA A AP P
Sbjct: 301 AAAAPPPAPPHHGAAAPPPGQLSPASPATAAPPAPAP 337
>gi|39812378 RAN binding protein 9 [Homo sapiens]
Length = 729
Score = 42.0 bits (97), Expect = 9e-04
Identities = 43/148 (29%), Positives = 55/148 (37%), Gaps = 9/148 (6%)
Query: 3 SGAQLPPQPSSSEVSAVQSP-----GGRPGAGLEETALGVPLPPSPGEAPLPRSNRSRCP 57
SG LP P+ VSA SP GG G GL A + L P P P + P
Sbjct: 31 SGVVLPAPPA---VSAGSSPAGSPGGGAGGEGLGAAAAALLLHPPPPPPPATAAPPPPPP 87
Query: 58 GTRQPGAASLHAASAAVPVRPRRGTAPAGKTADAVPAAAPEQAPRPAPQSRKPRNLEGDL 117
P +A+ A+ P G PAG A A A P P N +
Sbjct: 88 PPPPPASAAAPASGPPAPPGLAAGPGPAG-GAPTPALVAGSSAAAPFPHGDSALNEQEKE 146
Query: 118 DERRLLCHLQLAQDREARLWRGGKPQDE 145
+RRL ++E L R P+D+
Sbjct: 147 LQRRLKRLYPAVDEQETPLPRSWSPKDK 174
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 42.0 bits (97), Expect = 9e-04
Identities = 37/116 (31%), Positives = 43/116 (37%), Gaps = 15/116 (12%)
Query: 2 ASGAQLPPQPSSSEVSAVQSPGG----RPGAGLEETALGVPLPPSPGEA---PLPRSNRS 54
A GA P P+ PGG RPG L VP P+P A P P +
Sbjct: 82 APGAAPEPPPAGRA-----RPGGGGPQRPGPPSPRRPL-VPAGPAPPAAKLRPPPEGSAG 135
Query: 55 RCPGTRQPGAASLHAASAAVPVRPRRGTAPAGKTADAVPAAAPEQAPRPAPQSRKP 110
C P AA++ A P P + PA A A P P P P P KP
Sbjct: 136 SCAPV--PAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKP 189
Score = 40.0 bits (92), Expect = 0.003
Identities = 31/116 (26%), Positives = 42/116 (36%), Gaps = 16/116 (13%)
Query: 4 GAQLPPQPSSSEVSAVQSPGGRPGAGLEETALGVPLPPSPGEAPL------PRSNRSRCP 57
GA PP P++ A +P A P PP P A L P + P
Sbjct: 245 GAAAPPAPAAPSPPAAPAPAAPAAA---------PPPPPPAPATLARPPGHPAGPPTAAP 295
Query: 58 GTRQPGAASLHAASAAVPVRPRRGTAPAGKTADAVPAAAPEQAPRPAPQSRKPRNL 113
P AA ++ A P PAG + P AA AP P ++ P+ +
Sbjct: 296 AVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAA-AAAPAPGVKAESPKRV 350
Score = 33.9 bits (76), Expect = 0.24
Identities = 30/102 (29%), Positives = 39/102 (38%), Gaps = 2/102 (1%)
Query: 2 ASGAQLPPQPSSSEVSAVQSPGGRPGAGLEETALGVPLPPSPGEAPLP--RSNRSRCPGT 59
A+ A PP + + SA +P P AG G P P + AP P ++ +
Sbjct: 293 AAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQ 352
Query: 60 RQPGAASLHAASAAVPVRPRRGTAPAGKTADAVPAAAPEQAP 101
P AA AAS P + A PAA P AP
Sbjct: 353 AAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAP 394
Score = 32.7 bits (73), Expect = 0.53
Identities = 40/157 (25%), Positives = 52/157 (33%), Gaps = 44/157 (28%)
Query: 3 SGAQLPPQPSSSEVSAVQSPG----GRPGAGLEETALGVPLP-PSPGEAPLPRSNRSRCP 57
S P P+++ V+A P +P A P P P PG P P + P
Sbjct: 133 SAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGP 192
Query: 58 GTRQP--GAASL----HAAS---------------------------------AAVPVRP 78
G Q G+A+L HAA+ AA P P
Sbjct: 193 GAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAP 252
Query: 79 RRGTAPAGKTADAVPAAAPEQAPRPAPQSRKPRNLEG 115
+ PA A AA P P PA +R P + G
Sbjct: 253 AAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAG 289
Score = 32.0 bits (71), Expect = 0.91
Identities = 30/90 (33%), Positives = 35/90 (38%), Gaps = 6/90 (6%)
Query: 21 SPGGRPGAGLEETALGVP----LPPSPGEAPLPRSNRSRCPGTRQPGAASLHAASAAVPV 76
SP G GAG A G P PP G A P + PG P + A A
Sbjct: 66 SPAGAAGAGPAAPAEGAPGAAPEPPPAGRAR-PGGGGPQRPGPPSPRRPLVPAGPAPPAA 124
Query: 77 RPRRGTAPAGKTADAVPAAAPEQA-PRPAP 105
+ R + + VPAAA A P PAP
Sbjct: 125 KLRPPPEGSAGSCAPVPAAAAVAAGPEPAP 154
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 42.0 bits (97), Expect = 9e-04
Identities = 36/115 (31%), Positives = 41/115 (35%), Gaps = 9/115 (7%)
Query: 8 PPQPSSSEVSAVQSPGGRPGAGLEETALGVPLPPS-------PGEAPLPRSNRSRCPGTR 60
PPQ SS V A Q PG PG G A P + PG P P +
Sbjct: 102 PPQDSSKPVVA-QGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSA 160
Query: 61 QPGAASLHAASAAVPVRPRRGTAPAGKTADAVPAAAPEQAPRPAPQSRKPRNLEG 115
PGA S+ VP P + P A AVP P P P K + G
Sbjct: 161 PPGAPPPTPPSSGVPTTPPQAGGPPPPPA-AVPGPGPGPKQGPGPGGPKGGKMPG 214
Score = 32.3 bits (72), Expect = 0.70
Identities = 28/108 (25%), Positives = 37/108 (34%), Gaps = 13/108 (12%)
Query: 6 QLPPQPSSSEVSAVQSPGGRPGAGLEETALGVPLPPSPGEAPLPRSNRSRCPGTRQPGAA 65
Q PPQ + P P ++ P PP P+ PG +
Sbjct: 71 QPPPQQPPPQQPPPHQPPPHPQPHQQQQP---PPPPQDSSKPVVAQGPGPAPGV----GS 123
Query: 66 SLHAASAAVPVRPRRGTAPAGKTADAVP------AAAPEQAPRPAPQS 107
+ A+S+A P P AP G P +AP AP P P S
Sbjct: 124 APPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPS 171
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,136,581
Number of Sequences: 37866
Number of extensions: 901304
Number of successful extensions: 8457
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 111
Number of HSP's successfully gapped in prelim test: 741
Number of HSP's that attempted gapping in prelim test: 6668
Number of HSP's gapped (non-prelim): 2280
length of query: 369
length of database: 18,247,518
effective HSP length: 104
effective length of query: 265
effective length of database: 14,309,454
effective search space: 3792005310
effective search space used: 3792005310
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.