Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 8923870
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|8923870 solute carrier family 22 member 11 [Homo sapiens]
(550 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|8923870 solute carrier family 22 member 11 [Homo sapiens] 1089 0.0
gi|24497485 urate anion exchanger 1 isoform a [Homo sapiens] 560 e-159
gi|148664184 solute carrier family 22, member 10 [Homo sapiens] 491 e-139
gi|211059435 solute carrier family 22, member 24 [Homo sapiens] 452 e-127
gi|153791484 putative UST1-like organic anion transporter [Homo ... 446 e-125
gi|24497476 solute carrier family 22 member 6 isoform b [Homo sa... 437 e-122
gi|20070188 solute carrier family 22 member 6 isoform a [Homo sa... 435 e-122
gi|42542386 solute carrier family 22 (organic anion/cation trans... 424 e-118
gi|24497499 solute carrier family 22 member 8 [Homo sapiens] 415 e-116
gi|238814326 solute carrier family 22, member 20 [Homo sapiens] 412 e-115
gi|24497478 solute carrier family 22 member 6 isoform c [Homo sa... 387 e-107
gi|24497480 solute carrier family 22 member 6 isoform d [Homo sa... 385 e-107
gi|24497497 solute carrier family 22 member 7 isoform a [Homo sa... 295 6e-80
gi|90669191 solute carrier family 22 member 7 isoform b [Homo sa... 291 1e-78
gi|166064021 solute carrier family 22 (organic anion transporter... 285 8e-77
gi|24497487 urate anion exchanger 1 isoform b [Homo sapiens] 271 1e-72
gi|4507005 solute carrier family 22 member 5 [Homo sapiens] 223 3e-58
gi|4506999 solute carrier family 22 member 1 isoform a [Homo sap... 211 1e-54
gi|11415038 solute carrier family 22 member 3 [Homo sapiens] 208 9e-54
gi|4507001 solute carrier family 22 member 2 [Homo sapiens] 207 2e-53
gi|24497490 solute carrier family 22 member 4 [Homo sapiens] 206 6e-53
gi|157426885 organic cation transporter like 4 [Homo sapiens] 183 3e-46
gi|23510410 solute carrier family 22 member 1 isoform b [Homo sa... 180 3e-45
gi|31542327 solute carrier family 22, member 16 [Homo sapiens] 165 9e-41
gi|166197673 solute carrier family 22, member 15 [Homo sapiens] 157 2e-38
gi|169202895 PREDICTED: similar to solute carrier family 22, mem... 116 6e-26
gi|239750073 PREDICTED: similar to solute carrier family 22, mem... 116 6e-26
gi|239744382 PREDICTED: hypothetical protein XP_002343132 [Homo ... 116 6e-26
gi|170650643 solute carrier family 22, member 23 isoform a [Homo... 107 3e-23
gi|239745643 PREDICTED: hypothetical protein LOC146429 isoform 1... 105 1e-22
>gi|8923870 solute carrier family 22 member 11 [Homo sapiens]
Length = 550
Score = 1089 bits (2817), Expect = 0.0
Identities = 550/550 (100%), Positives = 550/550 (100%)
Query: 1 MAFSKLLEQAGGVGLFQTLQVLTFILPCLMIPSQMLLENFSAAIPGHRCWTHMLDNGSAV 60
MAFSKLLEQAGGVGLFQTLQVLTFILPCLMIPSQMLLENFSAAIPGHRCWTHMLDNGSAV
Sbjct: 1 MAFSKLLEQAGGVGLFQTLQVLTFILPCLMIPSQMLLENFSAAIPGHRCWTHMLDNGSAV 60
Query: 61 STNMTPKALLTISIPPGPNQGPHQCRRFRQPQWQLLDPNATATSWSEADTEPCVDGWVYD 120
STNMTPKALLTISIPPGPNQGPHQCRRFRQPQWQLLDPNATATSWSEADTEPCVDGWVYD
Sbjct: 61 STNMTPKALLTISIPPGPNQGPHQCRRFRQPQWQLLDPNATATSWSEADTEPCVDGWVYD 120
Query: 121 RSVFTSTIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYRFGRKPMLSWCCLQL 180
RSVFTSTIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYRFGRKPMLSWCCLQL
Sbjct: 121 RSVFTSTIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYRFGRKPMLSWCCLQL 180
Query: 181 AVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVVGCAFSA 240
AVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVVGCAFSA
Sbjct: 181 AVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVVGCAFSA 240
Query: 241 GQAALGGLAFALRDWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQELRKVA 300
GQAALGGLAFALRDWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQELRKVA
Sbjct: 241 GQAALGGLAFALRDWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQELRKVA 300
Query: 301 RINGHKEAKNLTIEVLMSSVKEEVASAKEPRSVLDLFCVPVLRWRSCAMLVVNFSLLISY 360
RINGHKEAKNLTIEVLMSSVKEEVASAKEPRSVLDLFCVPVLRWRSCAMLVVNFSLLISY
Sbjct: 301 RINGHKEAKNLTIEVLMSSVKEEVASAKEPRSVLDLFCVPVLRWRSCAMLVVNFSLLISY 360
Query: 361 YGLVFDLQSLGRDIFLLQALFGAVDFLGRATTALLLSFLGRRTIQAGSQAMAGLAILANM 420
YGLVFDLQSLGRDIFLLQALFGAVDFLGRATTALLLSFLGRRTIQAGSQAMAGLAILANM
Sbjct: 361 YGLVFDLQSLGRDIFLLQALFGAVDFLGRATTALLLSFLGRRTIQAGSQAMAGLAILANM 420
Query: 421 LVPQDLQTLRVVFAVLGKGCFGISLTCLTIYKAELFPTPVRMTADGILHTVGRLGAMMGP 480
LVPQDLQTLRVVFAVLGKGCFGISLTCLTIYKAELFPTPVRMTADGILHTVGRLGAMMGP
Sbjct: 421 LVPQDLQTLRVVFAVLGKGCFGISLTCLTIYKAELFPTPVRMTADGILHTVGRLGAMMGP 480
Query: 481 LILMSRQALPLLPPLLYGVISIASSLVVLFFLPETQGLPLPDTIQDLESQKSTAAQGNRQ 540
LILMSRQALPLLPPLLYGVISIASSLVVLFFLPETQGLPLPDTIQDLESQKSTAAQGNRQ
Sbjct: 481 LILMSRQALPLLPPLLYGVISIASSLVVLFFLPETQGLPLPDTIQDLESQKSTAAQGNRQ 540
Query: 541 EAVTVESTSL 550
EAVTVESTSL
Sbjct: 541 EAVTVESTSL 550
>gi|24497485 urate anion exchanger 1 isoform a [Homo sapiens]
Length = 553
Score = 560 bits (1443), Expect = e-159
Identities = 284/534 (53%), Positives = 372/534 (69%), Gaps = 5/534 (0%)
Query: 1 MAFSKLLEQAGGVGLFQTLQVLTFILPCLMIPSQMLLENFSAAIPGHRCWTHMLDNGSAV 60
MAFS+LL+ GG+G FQ LQ + ++ + + +Q +LENFSAA+P HRCW +LDN +A
Sbjct: 1 MAFSELLDLVGGLGRFQVLQTMALMVSIMWLCTQSMLENFSAAVPSHRCWAPLLDNSTAQ 60
Query: 61 ST---NMTPKALLTISIPPGPNQGPHQCRRFRQPQWQLLDPNATATSWSEADTEPCVDGW 117
++ +++P+ALL ISIPPGPNQ PHQCRRFRQPQWQLLDPNATATSWSEADTEPCVDGW
Sbjct: 61 ASILGSLSPEALLAISIPPGPNQRPHQCRRFRQPQWQLLDPNATATSWSEADTEPCVDGW 120
Query: 118 VYDRSVFTSTIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYRFGRKPMLSWCC 177
VYDRS+FTSTIVAKW+LVC S LKP++QSI+++GILVG+ G S RFGR+ +L+W
Sbjct: 121 VYDRSIFTSTIVAKWNLVCDSHALKPMAQSIYLAGILVGAAACGPASDRFGRRLVLTWSY 180
Query: 178 LQLAVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVVGCA 237
LQ+AV GT+ FAP F +YC RF+ AF +AG+ +++ TL++EWT R + MT+
Sbjct: 181 LQMAVMGTAAAFAPAFPVYCLFRFLLAFAVAGVMMNTGTLLMEWTAARARPLVMTLNSLG 240
Query: 238 FSAGQAALGGLAFALRDWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQELR 297
FS G +A+ +RDW LQL SVPFF L SWWL ESARWL+ G+ D LQEL
Sbjct: 241 FSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAESARWLLTTGRLDWGLQELW 300
Query: 298 KVARINGHKEAKN-LTIEVLMSSVKEEVASAKEPRSVLDLFCVPVLRWRSCAMLVVNFSL 356
+VA ING ++ LT EVL+S+++EE++ + P S+ L +P LR+R+C + F+
Sbjct: 301 RVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLLRMPGLRFRTCISTLCWFAF 360
Query: 357 LISYYGLVFDLQSLGRDIFLLQALFGAVDFLGRATTALLLSFLGRRTIQAGSQAMAGLAI 416
+++GL DLQ+LG +IFLLQ G VD + LLLS LGRR A S +AGL I
Sbjct: 361 GFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLSHLGRRPTLAASLLLAGLCI 420
Query: 417 LANMLVPQDLQTLRVVFAVLGKGCFGISLTCLTIYKAELFPTPVRMTADGILHTVGRLGA 476
LAN LVP ++ LR AVLG G G + TC+TIY +ELFPT +RMTA G+ R GA
Sbjct: 421 LANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFPTVLRMTAVGLGQMAARGGA 480
Query: 477 MMGPLILMSRQALPLLPPLLYGVISIASSLVVLFFLPETQGLPLPDTIQDLESQ 530
++GPL+ + P LP L+YG + + S L L LPETQ LPLPDTIQD+++Q
Sbjct: 481 ILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAAL-LLPETQSLPLPDTIQDVQNQ 533
>gi|148664184 solute carrier family 22, member 10 [Homo sapiens]
Length = 541
Score = 491 bits (1263), Expect = e-139
Identities = 268/536 (50%), Positives = 348/536 (64%), Gaps = 7/536 (1%)
Query: 1 MAFSKLLEQAGGVGLFQTLQVLTFILPCLMIP-SQMLLENFSAAIPGHRCWTHMLDN--G 57
MAF +LL Q GG+G FQ L L FILP LM+ +LLENF+AAIPGHRCW HMLDN G
Sbjct: 1 MAFEELLSQVGGLGRFQMLH-LVFILPSLMLLIPHILLENFAAAIPGHRCWVHMLDNNTG 59
Query: 58 SAVSTN-MTPKALLTISIPPGPNQGPHQCRRFRQPQWQLLDPNATATSWSEADTEPCVDG 116
S T ++ ALL ISIP N P +CRRF PQWQLL N T S SEADTEPCVDG
Sbjct: 60 SGNETGILSEDALLRISIPLDSNLRPEKCRRFVHPQWQLLHLNGTIHSTSEADTEPCVDG 119
Query: 117 WVYDRSVFTSTIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYRFGRKPMLSWC 176
WVYD+S F STIV KWDLVC Q LK + Q + ++G+LVG I G +S RFGR+ +L WC
Sbjct: 120 WVYDQSYFPSTIVTKWDLVCDYQSLKSVVQFLLLTGMLVGGIIGGHVSDRFGRRFILRWC 179
Query: 177 CLQLAVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVVGC 236
LQLA+ T FAPTF +YC LRF+A F I ++ + EW + +A+ + +
Sbjct: 180 LLQLAITDTCAAFAPTFPVYCVLRFLAGFSSMIIISNNSLPITEWIRPNSKALVVILSSG 239
Query: 237 AFSAGQAALGGLAFALRDWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQEL 296
A S GQ LGGLA+ RDW+TL + ASVPFF L+S WL ESARWLII K D+ L+ L
Sbjct: 240 ALSIGQIILGGLAYVFRDWQTLHVVASVPFFVFFLLSRWLVESARWLIITNKLDEGLKAL 299
Query: 297 RKVARINGHKEA-KNLTIEVLMSSVKEEVASAKEPRSVLDLFCVPVLRWRSCAMLVVNFS 355
RKVAR NG K A + L IEV+ S+++EE+ +A+ +V DLF P +R R C ++ + F+
Sbjct: 300 RKVARTNGIKNAEETLNIEVVRSTMQEELDAAQTKTTVCDLFRNPSMRKRICILVFLRFA 359
Query: 356 LLISYYGLVFDLQSLGRDIFLLQALFGAVDFLGRATTALLLSFLGRRTIQAGSQAMAGLA 415
I +YG + +LQ +G +IFLLQ L+GAV + R L L+ +GRR Q + GL+
Sbjct: 360 NTIPFYGTMVNLQHVGSNIFLLQVLYGAVALIVRCLALLTLNHMGRRISQILFMFLVGLS 419
Query: 416 ILANMLVPQDLQTLRVVFAVLGKGCFGISLTCLTIYKAELFPTPVRMTADGILHTVGRLG 475
ILAN VP+++QTLRV A LG GC + + + ++ EL PT +R A GI T R+G
Sbjct: 420 ILANTFVPKEMQTLRVALACLGIGCSAATFSSVAVHFIELIPTVLRARASGIDLTASRIG 479
Query: 476 AMMGPLILMSRQALPLLPPLLYGVISIASSLVVLFFLPETQGLPLPDTIQDLESQK 531
A + PL++ LP ++YG+ I L+V F LPET+ LPLPDTI+D+E+QK
Sbjct: 480 AALAPLLMTLTVFFTTLPWIIYGIFPIIGGLIV-FLLPETKNLPLPDTIKDVENQK 534
>gi|211059435 solute carrier family 22, member 24 [Homo sapiens]
Length = 551
Score = 452 bits (1162), Expect = e-127
Identities = 245/538 (45%), Positives = 334/538 (62%), Gaps = 7/538 (1%)
Query: 1 MAFSKLLEQAGGVGLFQTLQVLTFILPCLMIPSQMLLENFSAAIPGHRCWTHMLDNGSAV 60
M F LL+Q GG+G FQ + F + +++ ++LENF+A P HRCW +LDN + V
Sbjct: 1 MGFDVLLDQVGGMGRFQICLIAFFCITNILLFPNIVLENFTAFTPSHRCWVPLLDNDT-V 59
Query: 61 STN----MTPKALLTISIPPGPNQGPHQCRRFRQPQWQLLDPNATATSWSEADTEPCVDG 116
S N ++ LL ISIP N P +C+RF PQWQLL N T + +E DTEPCVDG
Sbjct: 60 SDNDTGTLSKDDLLRISIPLDSNLRPQKCQRFIHPQWQLLHLNGTFPNTNEPDTEPCVDG 119
Query: 117 WVYDRSVFTSTIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYRFGRKPMLSWC 176
WVYDRS F STIV +WDLVC SQ LK + QS+FM+G L+G I+G LS R GRK + C
Sbjct: 120 WVYDRSSFLSTIVTEWDLVCESQSLKSMVQSLFMAGSLLGGLIYGHLSDRVGRKIICKLC 179
Query: 177 CLQLAVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVVGC 236
LQLA++ T FAPTF++YC LRF+A F I ++ L +EWT R++T+ V+ C
Sbjct: 180 FLQLAISNTCAAFAPTFLVYCILRFLAGFSTMTILGNTFILSLEWTLPRSRSMTIMVLLC 239
Query: 237 AFSAGQAALGGLAFALRDWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQEL 296
++S GQ LGGLAFA++DW LQL S P + L SW + ESARWLII + D+ L+EL
Sbjct: 240 SYSVGQMLLGGLAFAIQDWHILQLTVSTPIIVLFLSSWKMVESARWLIINNQLDEGLKEL 299
Query: 297 RKVARINGHKEA-KNLTIEVLMSSVKEEVASAKEPRSVLDLFCVPVLRWRSCAMLVVNFS 355
R+VA ING K + LT E++ S++K+E+ + + S+ LF P LR R + V F+
Sbjct: 300 RRVAHINGKKNTEETLTTELVRSTMKKELDAVRIKTSIFSLFRAPKLRMRVFGLCFVRFA 359
Query: 356 LLISYYGLVFDLQSLGRDIFLLQALFGAVDFLGRATTALLLSFLGRRTIQAGSQAMAGLA 415
+ + +YGL+ +LQ LG ++ L Q L GAV F R + L L+ +GRR Q GL
Sbjct: 360 ITVPFYGLILNLQHLGSNVSLFQILCGAVTFTARCVSLLTLNHMGRRISQILFTFPVGLF 419
Query: 416 ILANMLVPQDLQTLRVVFAVLGKGCFGISLTCLTIYKAELFPTPVRMTADGILHTVGRLG 475
IL N +PQ++Q LRVV A LG G + +++ EL PT +R T GI GR G
Sbjct: 420 ILVNTFLPQEMQILRVVLATLGIGSVSAASNSASVHHNELVPTILRSTVAGINAVSGRTG 479
Query: 476 AMMGPLILMSRQALPLLPPLLYGVISIASSLVVLFFLPETQGLPLPDTIQDLESQKST 533
A + PL++ P LP + YGV I + V+L LPET+ LPLP+TIQD+E++K +
Sbjct: 480 AALAPLLMTLMAYSPHLPWISYGVFPILAVPVIL-LLPETRDLPLPNTIQDVENEKDS 536
>gi|153791484 putative UST1-like organic anion transporter [Homo
sapiens]
Length = 547
Score = 446 bits (1146), Expect = e-125
Identities = 243/534 (45%), Positives = 333/534 (62%), Gaps = 5/534 (0%)
Query: 1 MAFSKLLEQAGGVGLFQTLQVLTFILPCLMIPSQMLLENFSAAIPGHRCWTHMLDNGSAV 60
MAF LL+Q GG+G FQ LQ++ I+ +++ Q LENF+A I HRCW H+LDN +
Sbjct: 1 MAFQDLLDQVGGLGRFQILQMVFLIMFNVIVYHQTQLENFAAFILDHRCWVHILDNDTIP 60
Query: 61 STN---MTPKALLTISIPPGPNQGPHQCRRFRQPQWQLLDPNATATSWSEADTEPCVDGW 117
+ ++ ALL ISIP N P +CRRF PQW+L+ N T + SE DTEPCVDGW
Sbjct: 61 DNDPGTLSQDALLRISIPFDSNLRPEKCRRFVHPQWKLIHLNGTFPNTSEPDTEPCVDGW 120
Query: 118 VYDRSVFTSTIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYRFGRKPMLSWCC 177
VYD+S F STIV KWDLVC SQ L +++ +FM+G++VG ++G LS RFGRK +L W
Sbjct: 121 VYDQSSFPSTIVTKWDLVCESQPLNSVAKFLFMAGMMVGGNLYGHLSDRFGRKFVLRWSY 180
Query: 178 LQLAVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVVGCA 237
LQLA+ GT FAPT ++YC LRF+A I ++++ L+VEW T A+ +T+ CA
Sbjct: 181 LQLAIVGTCAAFAPTILVYCSLRFLAGAATFSIIVNTVLLIVEWITHQFCAMALTLTLCA 240
Query: 238 FSAGQAALGGLAFALRDWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQELR 297
S G LG LAF +RD LQL S P F L S WL ESARWLII KP++ L+ELR
Sbjct: 241 ASIGHITLGSLAFVIRDQCILQLVMSAPCFVFFLFSRWLAESARWLIINNKPEEGLKELR 300
Query: 298 KVARINGHKEAKN-LTIEVLMSSVKEEVASAKEPRSVLDLFCVPVLRWRSCAMLVVNFSL 356
K A NG K A++ LT+EVL S++K+E+ +A++ S+ +L +P + R C + V F+
Sbjct: 301 KAAHRNGMKNAEDILTMEVLKSTMKQELEAAQKKHSLCELLRIPNICKRICFLSFVRFAS 360
Query: 357 LISYYGLVFDLQSLGRDIFLLQALFGAVDFLGRATTALLLSFLGRRTIQAGSQAMAGLAI 416
I ++GL LQ LG ++FLLQ LFGAV L L+ + RR Q + +
Sbjct: 361 TIPFWGLTLHLQHLGNNVFLLQTLFGAVTLLANCVAPWALNHMSRRLSQMLLMFLLATCL 420
Query: 417 LANMLVPQDLQTLRVVFAVLGKGCFGISLTCLTIYKAELFPTPVRMTADGILHTVGRLGA 476
LA + VPQ++QTLRVV A LG G + +TC T + EL P+ +R A GI +G
Sbjct: 421 LAIIFVPQEMQTLRVVLATLGVGAASLGITCSTAQENELIPSIIRGRATGITGNFANIGG 480
Query: 477 MMGPLILMSRQALPLLPPLLYGVISIASSLVVLFFLPETQGLPLPDTIQDLESQ 530
+ L+++ LP ++YGV +I S LVVL LPET+ PL D+IQD+E++
Sbjct: 481 ALASLMMILSIYSRPLPWIIYGVFAILSGLVVL-LLPETRNQPLLDSIQDVENE 533
>gi|24497476 solute carrier family 22 member 6 isoform b [Homo
sapiens]
Length = 550
Score = 437 bits (1123), Expect = e-122
Identities = 229/532 (43%), Positives = 325/532 (61%), Gaps = 10/532 (1%)
Query: 1 MAFSKLLEQAGGVGLFQTLQVLTFILPCLMIPSQMLLENFSAAIPGHRCWTHMLDNGSAV 60
MAF+ LL+Q GGVG FQ +QV +LP L++ S L+NF+AAIP H C
Sbjct: 1 MAFNDLLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHC-------RPPA 53
Query: 61 STNMTPKALLTISIPPGPNQGPHQCRRFRQPQWQLLDPNATATSWSEADTEPCVDGWVYD 120
N++ L + +P P C RF PQW L N T + + A TEPC DGW+YD
Sbjct: 54 DANLSKNGGLEVWLPRDRQGQPESCLRFTSPQWGLPFLNGTEANGTGA-TEPCTDGWIYD 112
Query: 121 RSVFTSTIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYRFGRKPMLSWCCLQL 180
S F STIV +WDLVCS + L+ L+QS++M G+L+G+ ++G L+ R GR+ +L LQ
Sbjct: 113 NSTFPSTIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQT 172
Query: 181 AVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVVGCAFSA 240
AV+GT FAP F IYC R ++ +AGI L+ +TL VEW RA T++G +S
Sbjct: 173 AVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSL 232
Query: 241 GQAALGGLAFALRDWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQELRKVA 300
GQ L G+A+A+ WR LQL S PFFA + SW+ ESARW G+ D L+ L++VA
Sbjct: 233 GQFLLAGVAYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVA 292
Query: 301 RING-HKEAKNLTIEVLMSSVKEEVASAKEPRSVLDLFCVPVLRWRSCAMLVVNFSLLIS 359
RING +E L++EVL +S+++E+ K S ++L P LR + ++ F+ +
Sbjct: 293 RINGKREEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFA 352
Query: 360 YYGLVFDLQSLGRDIFLLQALFGAVDFLGRATTALLLSFLGRRTIQAGSQAMAGLAILAN 419
YYGLV DLQ G I+L+Q +FGAVD + L+++ LGRR Q + +AG+ IL N
Sbjct: 353 YYGLVMDLQGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLN 412
Query: 420 MLVPQDLQTLRVVFAVLGKGCFGISLTCLTIYKAELFPTPVRMTADGILHTVGRLGAMMG 479
++PQD +R AVLGKGC S C+ +Y EL+PT +R T G+ T+ R+G+++
Sbjct: 413 GVIPQDQSIVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVS 472
Query: 480 PLILMSRQALPLLPPLLYGVISIASSLVVLFFLPETQGLPLPDTIQDLESQK 531
PL+ M+ + P +P +YG + +A+S V + LPET G PLPDT+QDLES+K
Sbjct: 473 PLVSMTAELYPSMPLFIYGAVPVAASAVTV-LLPETLGQPLPDTVQDLESRK 523
>gi|20070188 solute carrier family 22 member 6 isoform a [Homo
sapiens]
Length = 563
Score = 435 bits (1118), Expect = e-122
Identities = 228/531 (42%), Positives = 324/531 (61%), Gaps = 10/531 (1%)
Query: 1 MAFSKLLEQAGGVGLFQTLQVLTFILPCLMIPSQMLLENFSAAIPGHRCWTHMLDNGSAV 60
MAF+ LL+Q GGVG FQ +QV +LP L++ S L+NF+AAIP H C
Sbjct: 1 MAFNDLLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHC-------RPPA 53
Query: 61 STNMTPKALLTISIPPGPNQGPHQCRRFRQPQWQLLDPNATATSWSEADTEPCVDGWVYD 120
N++ L + +P P C RF PQW L N T + + A TEPC DGW+YD
Sbjct: 54 DANLSKNGGLEVWLPRDRQGQPESCLRFTSPQWGLPFLNGTEANGTGA-TEPCTDGWIYD 112
Query: 121 RSVFTSTIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYRFGRKPMLSWCCLQL 180
S F STIV +WDLVCS + L+ L+QS++M G+L+G+ ++G L+ R GR+ +L LQ
Sbjct: 113 NSTFPSTIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQT 172
Query: 181 AVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVVGCAFSA 240
AV+GT FAP F IYC R ++ +AGI L+ +TL VEW RA T++G +S
Sbjct: 173 AVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSL 232
Query: 241 GQAALGGLAFALRDWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQELRKVA 300
GQ L G+A+A+ WR LQL S PFFA + SW+ ESARW G+ D L+ L++VA
Sbjct: 233 GQFLLAGVAYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVA 292
Query: 301 RING-HKEAKNLTIEVLMSSVKEEVASAKEPRSVLDLFCVPVLRWRSCAMLVVNFSLLIS 359
RING +E L++EVL +S+++E+ K S ++L P LR + ++ F+ +
Sbjct: 293 RINGKREEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFA 352
Query: 360 YYGLVFDLQSLGRDIFLLQALFGAVDFLGRATTALLLSFLGRRTIQAGSQAMAGLAILAN 419
YYGLV DLQ G I+L+Q +FGAVD + L+++ LGRR Q + +AG+ IL N
Sbjct: 353 YYGLVMDLQGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLN 412
Query: 420 MLVPQDLQTLRVVFAVLGKGCFGISLTCLTIYKAELFPTPVRMTADGILHTVGRLGAMMG 479
++PQD +R AVLGKGC S C+ +Y EL+PT +R T G+ T+ R+G+++
Sbjct: 413 GVIPQDQSIVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVS 472
Query: 480 PLILMSRQALPLLPPLLYGVISIASSLVVLFFLPETQGLPLPDTIQDLESQ 530
PL+ M+ + P +P +YG + +A+S V + LPET G PLPDT+QDLES+
Sbjct: 473 PLVSMTAELYPSMPLFIYGAVPVAASAVTV-LLPETLGQPLPDTVQDLESR 522
>gi|42542386 solute carrier family 22 (organic anion/cation
transporter), member 9 [Homo sapiens]
Length = 553
Score = 424 bits (1089), Expect = e-118
Identities = 237/554 (42%), Positives = 332/554 (59%), Gaps = 9/554 (1%)
Query: 1 MAFSKLLEQAGGVGLFQTLQVLTFILPCLMIPSQMLLENFSAAIPGHRCWTHMLDNGSAV 60
MAF LL AG + FQ LQ + + + +LENF+A IPGHRCW H+LDN + V
Sbjct: 1 MAFQDLLGHAGDLWRFQILQTVFLSIFAVATYLHFMLENFTAFIPGHRCWVHILDNDT-V 59
Query: 61 STN----MTPKALLTISIPPGPNQGPHQCRRFRQPQWQLLDPNATATSWSEADTEPCVDG 116
S N ++ ALL ISIP N P +CRRF PQWQLL N T + S+AD EPCVDG
Sbjct: 60 SDNDTGALSQDALLRISIPLDSNMRPEKCRRFVHPQWQLLHLNGTFPNTSDADMEPCVDG 119
Query: 117 WVYDRSVFTSTIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYRFGRKPMLSWC 176
WVYDR F+STIV +WDLVC SQ L +++ +FM+G++VG + G LS RFGR+ +L WC
Sbjct: 120 WVYDRISFSSTIVTEWDLVCDSQSLTSVAKFVFMAGMMVGGILGGHLSDRFGRRFVLRWC 179
Query: 177 CLQLAVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVVGC 236
LQ+A+ GT APTF+IYC LRF++ + +++ L+ EW T +A+ +T+ C
Sbjct: 180 YLQVAIVGTCAALAPTFLIYCSLRFLSGIAAMSLITNTIMLIAEWATHRFQAMGITLGMC 239
Query: 237 AFSAGQAALGGLAFALRDWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQEL 296
L GLAFA+RDW LQL SVP+F I L S WL ESARWLII KP++ L+EL
Sbjct: 240 PSGIAFMTLAGLAFAIRDWHILQLVVSVPYFVIFLTSSWLLESARWLIINNKPEEGLKEL 299
Query: 297 RKVARINGHKEAKN-LTIEVLMSSVKEEV-ASAKEPRSVLDLFCVPVLRWRSCAMLVVNF 354
RK A +G K A++ LT+E+L S++K+E+ A+ K+ S+ ++ +P + R + F
Sbjct: 300 RKAAHRSGMKNARDTLTLEILKSTMKKELEAAQKKKPSLCEMLHMPNICKRISLLSFTRF 359
Query: 355 SLLISYYGLVFDLQSLGRDIFLLQALFGAVDFLGRATTALLLSFLGRRTIQAGSQAMAGL 414
+ ++Y+GL +Q LG ++FLLQ LFGAV L L ++ RR Q + +
Sbjct: 360 ANFMAYFGLNLHVQHLGNNVFLLQTLFGAVILLANCVAPWALKYMNRRASQMLLMFLLAI 419
Query: 415 AILANMLVPQDLQTLRVVFAVLGKGCFGISLTCLTIYKAELFPTPVRMTADGILHTVGRL 474
+LA + VPQ++QTLR V A LG G ++ T + E+ PT +R A GI T +
Sbjct: 420 CLLAIIFVPQEMQTLREVLATLGLGASALANTLAFAHGNEVIPTIIRARAMGINATFANI 479
Query: 475 GAMMGPLILMSRQALPLLPPLLYGVISIASSLVVLFFLPETQGLPLPDTIQDLESQKSTA 534
+ PL+++ P LP ++YGV S L LPET+ PL DTIQD ++++
Sbjct: 480 AGALAPLMMILSVYSPPLPWIIYGVFPFISGFAFL-LLPETRNKPLFDTIQDEKNERKDP 538
Query: 535 AQGNRQEAVTVEST 548
+ +QE VE T
Sbjct: 539 RE-PKQEDPRVEVT 551
>gi|24497499 solute carrier family 22 member 8 [Homo sapiens]
Length = 542
Score = 415 bits (1067), Expect = e-116
Identities = 226/545 (41%), Positives = 330/545 (60%), Gaps = 24/545 (4%)
Query: 1 MAFSKLLEQAGGVGLFQTLQVLTFILPCLMIPSQMLLENFSAAIPGHRCWT-HMLDNGSA 59
M FS++L++ G +G FQ L V LP L + + LL+ F+AA P H C H G
Sbjct: 1 MTFSEILDRVGSMGHFQFLHVAILGLPILNMANHNLLQIFTAATPVHHCRPPHNASTGPW 60
Query: 60 VSTNMTPKALLTISIPPGPNQGPHQCRRFRQPQWQLLDPNATATSWSEADTEPCVDGWVY 119
V +P GPN P +C RF P PNA+ + ++ EPC+DGWVY
Sbjct: 61 V-------------LPMGPNGKPERCLRFVHP------PNASLPNDTQRAMEPCLDGWVY 101
Query: 120 DRSVFTSTIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYRFGRKPMLSWCCLQ 179
+ + +IV +WDLVC+S LK ++QSIFM+GIL+G + G LS RFGR+P+L+ L
Sbjct: 102 NST--KDSIVTEWDLVCNSNKLKEMAQSIFMAGILIGGLVLGDLSDRFGRRPILTCSYLL 159
Query: 180 LAVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVVGCAFS 239
LA +G+ F+PTF IY RF+ FG++GI LS++ L VEW T RA+ T +G ++
Sbjct: 160 LAASGSGAAFSPTFPIYMVFRFLCGFGISGITLSTVILNVEWVPTRMRAIMSTALGYCYT 219
Query: 240 AGQAALGGLAFALRDWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQELRKV 299
GQ L GLA+A+ WR LQL S+PFF L SWW PES RWL++ GK +AL+ LR+V
Sbjct: 220 FGQFILPGLAYAIPQWRWLQLTVSIPFFVFFLSSWWTPESIRWLVLSGKSSKALKILRRV 279
Query: 300 ARINGHK-EAKNLTIEVLMSSVKEEVASAKEPRSVLDLFCVPVLRWRSCAMLVVNFSLLI 358
A NG K E + L++E L ++++E++ AK + DLF +P+LR + + + F+
Sbjct: 280 AVFNGKKEEGERLSLEELKLNLQKEISLAKAKYTASDLFRIPMLRRMTFCLSLAWFATGF 339
Query: 359 SYYGLVFDLQSLGRDIFLLQALFGAVDFLGRATTALLLSFLGRRTIQAGSQAMAGLAILA 418
+YY L ++ G ++++LQ +FG VD + T L LS+LGR T QA + +AG AILA
Sbjct: 340 AYYSLAMGVEEFGVNLYILQIIFGGVDVPAKFITILSLSYLGRHTTQAAALLLAGGAILA 399
Query: 419 NMLVPQDLQTLRVVFAVLGKGCFGISLTCLTIYKAELFPTPVRMTADGILHTVGRLGAMM 478
VP DLQT+R V AV GKGC S +CL +Y +EL+PT +R T G+ + R+G+M+
Sbjct: 400 LTFVPLDLQTVRTVLAVFGKGCLSSSFSCLFLYTSELYPTVIRQTGMGVSNLWTRVGSMV 459
Query: 479 GPLILMSRQALPLLPPLLYGVISIASSLVVLFFLPETQGLPLPDTIQDLESQKSTAAQGN 538
PL+ ++ + P +P ++YG+ ++ L FLPET PLP+TI+DLE+ A +
Sbjct: 460 SPLVKITGEVQPFIPNIIYGITALLGGSAAL-FLPETLNQPLPETIEDLENWSLRAKKPK 518
Query: 539 RQEAV 543
++ V
Sbjct: 519 QEPEV 523
>gi|238814326 solute carrier family 22, member 20 [Homo sapiens]
Length = 555
Score = 412 bits (1058), Expect = e-115
Identities = 220/529 (41%), Positives = 313/529 (59%), Gaps = 8/529 (1%)
Query: 1 MAFSKLLEQAGGVGLFQTLQVLTFILPCLMIPSQMLLENFSAAIPGHRCWTHMLDNGSAV 60
MAF+ LL+ G +G FQ +LPC ++ L+NF+AA+P H C N +
Sbjct: 1 MAFTDLLDALGSMGRFQLNHTALLLLPCGLLACHNFLQNFTAAVPPHHCRGPA--NHTEA 58
Query: 61 STNMTPKALLTISIPPGPNQGPHQCRRFRQPQWQLLDPNATATSWSEADTEPCVDGWVYD 120
STN + A L +IP P CRRF +PQW LL PN++ A TE C DGWVY+
Sbjct: 59 STNDSG-AWLRATIPLDQLGAPEPCRRFTKPQWALLSPNSSIPG---AATEGCKDGWVYN 114
Query: 121 RSVFTSTIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYRFGRKPMLSWCCLQL 180
RSVF STIV +WDLVC ++ L+ L+QS++M+G+LVG+ ++G L+ R G K L W LQL
Sbjct: 115 RSVFPSTIVMEWDLVCEARTLRDLAQSVYMAGVLVGAAVFGSLADRLGCKGPLVWSYLQL 174
Query: 181 AVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVVGCAFSA 240
A +G +T + +F YC RF+ +GI L+S++L+VEW T R V ++G +F+
Sbjct: 175 AASGAATAYFSSFSAYCVFRFLMGMTFSGIILNSVSLVVEWMPTRGRTVAGILLGYSFTL 234
Query: 241 GQAALGGLAFALRDWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQELRKVA 300
GQ L G+A+ +R WR LQ A S PF L SWWLPES+RWL++ GK A+Q L+KVA
Sbjct: 235 GQLILAGVAYLIRPWRCLQFAISAPFLIFFLYSWWLPESSRWLLLHGKSQLAVQNLQKVA 294
Query: 301 RINGHK-EAKNLTIEVLMSSVKEEVASAKEPRSVLDLFCVPVLRWRSCAMLVVNFSLLIS 359
+NG K E + LT EV+ S ++ E AS S+LDLF P +R +C ++V+ FS ++
Sbjct: 295 AMNGRKEEGERLTKEVMSSYIQSEFASVCTSNSILDLFRTPAIRKVTCCLMVIWFSNSVA 354
Query: 360 YYGLVFDLQSLGRDIFLLQALFGAVDFLGRATTALLLSFLGRRTIQAGSQAMAGLAILAN 419
YYGL DLQ G ++L+QALFG ++ + ++GRR A +AGL ++AN
Sbjct: 355 YYGLAMDLQKFGLSLYLVQALFGIINTPAMLVATATMIYVGRRATVASFLILAGLMVIAN 414
Query: 420 MLVPQDLQTLRVVFAVLGKGCFGISLTCLTIYKAELFPTPVRMTADGILHTVGRLGAMMG 479
M VP+ Q L A LGKGC S C+ ++ EL+PT +R G RLG +
Sbjct: 415 MFVPEGTQILCTAQAALGKGCLASSFICVYLFTGELYPTEIRQMGMGFASVHARLGGLTA 474
Query: 480 PLILMSRQALPLLPPLLYGVISIASSLVVLFFLPETQGLPLPDTIQDLE 528
PL+ + +LPP+ +G +I + L V L ET+ +PL +TI +E
Sbjct: 475 PLVTTLGEYSTILPPVSFGATAILAGLAVC-VLTETRNMPLVETIAAME 522
>gi|24497478 solute carrier family 22 member 6 isoform c [Homo
sapiens]
Length = 506
Score = 387 bits (995), Expect = e-107
Identities = 215/532 (40%), Positives = 296/532 (55%), Gaps = 54/532 (10%)
Query: 1 MAFSKLLEQAGGVGLFQTLQVLTFILPCLMIPSQMLLENFSAAIPGHRCWTHMLDNGSAV 60
MAF+ LL+Q GGVG FQ +QV +LP L++ S L+NF+AAIP H C
Sbjct: 1 MAFNDLLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHC-------RPPA 53
Query: 61 STNMTPKALLTISIPPGPNQGPHQCRRFRQPQWQLLDPNATATSWSEADTEPCVDGWVYD 120
N++ L + +P P C RF PQW L N T + + A TEPC DGW+YD
Sbjct: 54 DANLSKNGGLEVWLPRDRQGQPESCLRFTSPQWGLPFLNGTEANGTGA-TEPCTDGWIYD 112
Query: 121 RSVFTSTIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYRFGRKPMLSWCCLQL 180
S F STIV +WDLVCS + L+ L+QS++M G+L+G+ ++G L+ R GR+ +L LQ
Sbjct: 113 NSTFPSTIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQT 172
Query: 181 AVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVVGCAFSA 240
AV+GT FAP F IYC R ++ +AGI L+ +TL VEW RA T++G +S
Sbjct: 173 AVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSL 232
Query: 241 GQAALGGLAFALRDWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQELRKVA 300
GQ L G+A+A+ WR LQL S PFFA + SW+ ESARW G+ D L+ L++VA
Sbjct: 233 GQFLLAGVAYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVA 292
Query: 301 RING-HKEAKNLTIEVLMSSVKEEVASAKEPRSVLDLFCVPVLRWRSCAMLVVNFSLLIS 359
RING +E L++EVL +S+++E+ K S ++L P LR + ++ F+ +
Sbjct: 293 RINGKREEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFA 352
Query: 360 YYGLVFDLQSLGRDIFLLQALFGAVDFLGRATTALLLSFLGRRTIQAGSQAMAGLAILAN 419
YYGLV DLQ G I+L+Q +FGAVD + L+++ LGRR Q + +AG+ IL N
Sbjct: 353 YYGLVMDLQGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLN 412
Query: 420 MLVPQDLQTLRVVFAVLGKGCFGISLTCLTIYKAELFPTPVRMTADGILHTVGRLGAMMG 479
++PQD +R AVLGKGC S C+ +Y EL+PT +R
Sbjct: 413 GVIPQDQSIVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIR------------------ 454
Query: 480 PLILMSRQALPLLPPLLYGVISIASSLVVLFFLPETQGLPLPDTIQDLESQK 531
V LPET G PLPDT+QDLES+K
Sbjct: 455 ---------------------------AVTVLLPETLGQPLPDTVQDLESRK 479
>gi|24497480 solute carrier family 22 member 6 isoform d [Homo
sapiens]
Length = 519
Score = 385 bits (990), Expect = e-107
Identities = 214/531 (40%), Positives = 295/531 (55%), Gaps = 54/531 (10%)
Query: 1 MAFSKLLEQAGGVGLFQTLQVLTFILPCLMIPSQMLLENFSAAIPGHRCWTHMLDNGSAV 60
MAF+ LL+Q GGVG FQ +QV +LP L++ S L+NF+AAIP H C
Sbjct: 1 MAFNDLLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHC-------RPPA 53
Query: 61 STNMTPKALLTISIPPGPNQGPHQCRRFRQPQWQLLDPNATATSWSEADTEPCVDGWVYD 120
N++ L + +P P C RF PQW L N T + + A TEPC DGW+YD
Sbjct: 54 DANLSKNGGLEVWLPRDRQGQPESCLRFTSPQWGLPFLNGTEANGTGA-TEPCTDGWIYD 112
Query: 121 RSVFTSTIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYRFGRKPMLSWCCLQL 180
S F STIV +WDLVCS + L+ L+QS++M G+L+G+ ++G L+ R GR+ +L LQ
Sbjct: 113 NSTFPSTIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQT 172
Query: 181 AVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVVGCAFSA 240
AV+GT FAP F IYC R ++ +AGI L+ +TL VEW RA T++G +S
Sbjct: 173 AVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSL 232
Query: 241 GQAALGGLAFALRDWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQELRKVA 300
GQ L G+A+A+ WR LQL S PFFA + SW+ ESARW G+ D L+ L++VA
Sbjct: 233 GQFLLAGVAYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVA 292
Query: 301 RING-HKEAKNLTIEVLMSSVKEEVASAKEPRSVLDLFCVPVLRWRSCAMLVVNFSLLIS 359
RING +E L++EVL +S+++E+ K S ++L P LR + ++ F+ +
Sbjct: 293 RINGKREEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFA 352
Query: 360 YYGLVFDLQSLGRDIFLLQALFGAVDFLGRATTALLLSFLGRRTIQAGSQAMAGLAILAN 419
YYGLV DLQ G I+L+Q +FGAVD + L+++ LGRR Q + +AG+ IL N
Sbjct: 353 YYGLVMDLQGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLN 412
Query: 420 MLVPQDLQTLRVVFAVLGKGCFGISLTCLTIYKAELFPTPVRMTADGILHTVGRLGAMMG 479
++PQD +R AVLGKGC S C+ +Y EL+PT +R
Sbjct: 413 GVIPQDQSIVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIR------------------ 454
Query: 480 PLILMSRQALPLLPPLLYGVISIASSLVVLFFLPETQGLPLPDTIQDLESQ 530
V LPET G PLPDT+QDLES+
Sbjct: 455 ---------------------------AVTVLLPETLGQPLPDTVQDLESR 478
>gi|24497497 solute carrier family 22 member 7 isoform a [Homo
sapiens]
Length = 546
Score = 295 bits (756), Expect = 6e-80
Identities = 187/540 (34%), Positives = 273/540 (50%), Gaps = 18/540 (3%)
Query: 1 MAFSKLLEQAGGVGLFQTLQVLTFILPCLMIPSQMLLENFSAAIPGHRCWTHMLDNGSAV 60
M F +LLEQ GG G FQ V LP +++P LL F AA+P HRC L A
Sbjct: 1 MGFEELLEQVGGFGPFQLRNVALLALPRVLLPLHFLLPIFLAAVPAHRC---ALPGAPAN 57
Query: 61 STNMTPKALLTISIPPGPNQGPHQCRRFRQPQWQLLDPNATATSW--------SEADTEP 112
++ L +P P+ C RF PQ PN T E T P
Sbjct: 58 FSHQD--VWLEAHLPREPDGTLSSCLRFAYPQAL---PNTTLGEERQSRGELEDEPATVP 112
Query: 113 CVDGWVYDRSVFTSTIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYRFGRKPM 172
C GW YD S F+STI +WDLVC +GL + + F +G+LVG+ +G LS RFGR+ +
Sbjct: 113 CSQGWEYDHSEFSSTIATEWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRL 172
Query: 173 LSWCCLQLAVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMT 232
L + V G ++ + ++V++ R + +AG + + L +EW R V
Sbjct: 173 LLVAYVSTLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPLELEWLDVEHRTVAGV 232
Query: 233 VVGCAFSAGQAALGGLAFALRDWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQA 292
+ ++ G L + + +RDWR L LA ++P L WW+PESARWL+ +G +A
Sbjct: 233 LSSTFWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEA 292
Query: 293 LQELRKVARINGHKEAKNLTIEVLMSSVKEEVASAKEPRSVLDLFCVPVLRWRSCAMLVV 352
+ L AR+NG ++ + +S V + P S LDLF P LR S +VV
Sbjct: 293 HRYLLHCARLNGRPVCEDSFSQEAVSKVAAGERVVRRP-SYLDLFRTPRLRHISLCCVVV 351
Query: 353 NFSLLISYYGLVFDLQSLGRDIFLLQALFGAVDFLGRATTALLLSFLGRRTIQAGSQAMA 412
F + SYYGL D+ LG +++ Q LFGAV+ + L + + GRR QAG+
Sbjct: 352 WFGVNFSYYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGT 411
Query: 413 GLAILANMLVPQDLQTLRVVFAVLGKGCFGISLTCLTIYKAELFPTPVRMTADGILHTVG 472
LA +LV D+++ V AV+GK + T ++ +EL+PT +R T G+ VG
Sbjct: 412 ALAFGTRLLVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVG 471
Query: 473 RLGAMMGPLILMSRQALPLLPPLLYGVISIASSLVVLFFLPETQGLPLPDTIQDLESQKS 532
RLG + PL + LP L YG I++ ++ L LPET+ LP+TIQD+E + +
Sbjct: 472 RLGGSLAPLAALLDGVWLSLPKLTYGGIALLAAGTAL-LLPETRQAQLPETIQDVERKSA 530
>gi|90669191 solute carrier family 22 member 7 isoform b [Homo
sapiens]
Length = 548
Score = 291 bits (744), Expect = 1e-78
Identities = 187/542 (34%), Positives = 274/542 (50%), Gaps = 20/542 (3%)
Query: 1 MAFSKLLEQAGGVGLFQTLQVLTFILPCLMIPSQMLLENFSAAIPGHRCWTHMLDNGSAV 60
M F +LLEQ GG G FQ V LP +++P LL F AA+P HRC L A
Sbjct: 1 MGFEELLEQVGGFGPFQLRNVALLALPRVLLPLHFLLPIFLAAVPAHRC---ALPGAPAN 57
Query: 61 STNMTPKALLTISIPPGPNQGPHQCRRFRQPQWQLLDPNATATSW--------SEADTEP 112
++ L +P P+ C RF PQ PN T E T P
Sbjct: 58 FSHQD--VWLEAHLPREPDGTLSSCLRFAYPQAL---PNTTLGEERQSRGELEDEPATVP 112
Query: 113 CVDGWVYDRSVFTSTIV--AKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYRFGRK 170
C GW YD S F+STI ++WDLVC +GL + + F +G+LVG+ +G LS RFGR+
Sbjct: 113 CSQGWEYDHSEFSSTIATESQWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRR 172
Query: 171 PMLSWCCLQLAVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVT 230
+L + V G ++ + ++V++ R + +AG + + L +EW R V
Sbjct: 173 RLLLVAYVSTLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPLELEWLDVEHRTVA 232
Query: 231 MTVVGCAFSAGQAALGGLAFALRDWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPD 290
+ ++ G L + + +RDWR L LA ++P L WW+PESARWL+ +G
Sbjct: 233 GVLSSTFWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGHVK 292
Query: 291 QALQELRKVARINGHKEAKNLTIEVLMSSVKEEVASAKEPRSVLDLFCVPVLRWRSCAML 350
+A + L AR+NG ++ + +S V + P S LDLF P LR S +
Sbjct: 293 EAHRYLLHCARLNGRPVCEDSFSQEAVSKVAAGERVVRRP-SYLDLFRTPRLRHISLCCV 351
Query: 351 VVNFSLLISYYGLVFDLQSLGRDIFLLQALFGAVDFLGRATTALLLSFLGRRTIQAGSQA 410
VV F + SYYGL D+ LG +++ Q LFGAV+ + L + + GRR QAG+
Sbjct: 352 VVWFGVNFSYYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLL 411
Query: 411 MAGLAILANMLVPQDLQTLRVVFAVLGKGCFGISLTCLTIYKAELFPTPVRMTADGILHT 470
LA +LV D+++ V AV+GK + T ++ +EL+PT +R T G+
Sbjct: 412 GTALAFGTRLLVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTAL 471
Query: 471 VGRLGAMMGPLILMSRQALPLLPPLLYGVISIASSLVVLFFLPETQGLPLPDTIQDLESQ 530
VGRLG + PL + LP L YG I++ ++ L LPET+ LP+TIQD+E +
Sbjct: 472 VGRLGGSLAPLAALLDGVWLSLPKLTYGGIALLAAGTAL-LLPETRQAQLPETIQDVERK 530
Query: 531 KS 532
+
Sbjct: 531 SA 532
>gi|166064021 solute carrier family 22 (organic anion transporter),
member 13 [Homo sapiens]
Length = 551
Score = 285 bits (729), Expect = 8e-77
Identities = 177/547 (32%), Positives = 279/547 (51%), Gaps = 26/547 (4%)
Query: 3 FSKLLEQAGGVGLFQTLQVLTFILPCLMIPSQMLLENFSAAIPGHRCWTHMLDNGSAVST 62
F ++L + G G FQ ++ + + P F H C + N +
Sbjct: 4 FVQVLAEIGDFGRFQIQLLILLCVLNFLSPFYFFAHVFMVLDEPHHCAVAWVKNHTF--- 60
Query: 63 NMTPKALLTISIPPGPNQGPHQCRRFRQPQWQLLDPNATATSWSEADTEPCVDGWVYDRS 122
N++ L +S+P P C FR P + + ++E T+PC GW Y +
Sbjct: 61 NLSAAEQLVLSVPLDTAGHPEPCLMFRPPPANASLQDILSHRFNE--TQPCDMGWEYPEN 118
Query: 123 VFTSTIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYRFGRKPMLSWCCLQLAV 182
S + +++LVC + LK +QS+FM+G+LVG+ ++G L R GRK + L +
Sbjct: 119 RLPS-LKNEFNLVCDRKHLKDTTQSVFMAGLLVGTLMFGPLCDRIGRKATILAQLLLFTL 177
Query: 183 AGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVVGCAFSAGQ 242
G +T F P+F +Y LRF A +AG+ S++TL+ EW S R + + C FS GQ
Sbjct: 178 IGLATAFVPSFELYMALRFAVATAVAGLSFSNVTLLTEWVGPSWRTQAVVLAQCNFSLGQ 237
Query: 243 AALGGLAFALRDWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQELRKVARI 302
L GLA+ R+WR LQ+ + P + W LPESARWL+ +G+ D+A+Q ++K A +
Sbjct: 238 MVLAGLAYGFRNWRLLQITGTAPGLLLFFYFWALPESARWLLTRGRMDEAIQLIQKAASV 297
Query: 303 NGHKEAKNLTIEVLMSSVKEEVASAKEPRSVLDLFCVPVLRWRSCAMLVVNFSLLISYYG 362
N K L+ E++ V E+ + + LDLF P LR + + V F + YYG
Sbjct: 298 NRRK----LSPELMNQLVPEKTGPS---GNALDLFRHPQLRKVTLIIFCVWFVDSLGYYG 350
Query: 363 LVFDLQSLGRDIFLLQALFGAVDFLGRATTALLLSFLGRRTIQAGSQAMAGLAILANMLV 422
L + G D++L Q +FGAV+ R ++ ++ GR+ Q G+ + GL + + +
Sbjct: 351 LSLQVGDFGLDVYLTQLIFGAVEVPARCSSIFMMQRFGRKWSQLGTLVLGGLMCIIIIFI 410
Query: 423 PQDLQTLRVVFAVLGKGCFGISLTCLTIYKAELFPTPVRMTADGILHTVGRLGAMMGPLI 482
P DL + + AV+GK + T +Y AELFPT +R T G++ R+G ++ PL+
Sbjct: 411 PADLPVVVTMLAVVGKMATAAAFTISYVYSAELFPTILRQTGMGLVGIFSRIGGILTPLV 470
Query: 483 LMSRQALPLLPPLLYGVISIASSLVVLFFLPETQGLPLPDTIQDLE------------SQ 530
++ + LP L+YG + I + L+ LPET G L DT+QDLE S+
Sbjct: 471 ILLGEYHAALPMLIYGSLPIVAGLLCT-LLPETHGQGLKDTLQDLELGPHPRSPKSVPSE 529
Query: 531 KSTAAQG 537
K T A+G
Sbjct: 530 KETEAKG 536
>gi|24497487 urate anion exchanger 1 isoform b [Homo sapiens]
Length = 332
Score = 271 bits (693), Expect = 1e-72
Identities = 148/313 (47%), Positives = 196/313 (62%), Gaps = 2/313 (0%)
Query: 219 VEWTTTSRRAVTMTVVGCAFSAGQAALGGLAFALRDWRTLQLAASVPFFAISLISWWLPE 278
+EWT R + MT+ FS G +A+ +RDW LQL SVPFF L SWWL E
Sbjct: 1 MEWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAE 60
Query: 279 SARWLIIKGKPDQALQELRKVARINGHKEAKN-LTIEVLMSSVKEEVASAKEPRSVLDLF 337
SARWL+ G+ D LQEL +VA ING ++ LT EVL+S+++EE++ + P S+ L
Sbjct: 61 SARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLL 120
Query: 338 CVPVLRWRSCAMLVVNFSLLISYYGLVFDLQSLGRDIFLLQALFGAVDFLGRATTALLLS 397
+P LR+R+C + F+ +++GL DLQ+LG +IFLLQ G VD + LLLS
Sbjct: 121 RMPGLRFRTCISTLCWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLS 180
Query: 398 FLGRRTIQAGSQAMAGLAILANMLVPQDLQTLRVVFAVLGKGCFGISLTCLTIYKAELFP 457
LGRR A S +AGL ILAN LVP ++ LR AVLG G G + TC+TIY +ELFP
Sbjct: 181 HLGRRPTLAASLLLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFP 240
Query: 458 TPVRMTADGILHTVGRLGAMMGPLILMSRQALPLLPPLLYGVISIASSLVVLFFLPETQG 517
T +RMTA G+ R GA++GPL+ + P LP L+YG + + S L L LPETQ
Sbjct: 241 TVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAAL-LLPETQS 299
Query: 518 LPLPDTIQDLESQ 530
LPLPDTIQD+++Q
Sbjct: 300 LPLPDTIQDVQNQ 312
>gi|4507005 solute carrier family 22 member 5 [Homo sapiens]
Length = 557
Score = 223 bits (569), Expect = 3e-58
Identities = 164/525 (31%), Positives = 258/525 (49%), Gaps = 20/525 (3%)
Query: 11 GGVGLFQTLQVLTFILPCLMIPSQM--LLENFSAAIPGHRCWTHMLDNGSAVSTNMTPKA 68
G G FQ L + F+L +IP+ L F A P HRC N S+ N T
Sbjct: 12 GEWGPFQRL--IFFLLSASIIPNGFTGLSSVFLIATPEHRCRVPDAANLSSAWRNHT--- 66
Query: 69 LLTISIPPGPNQGPHQCRRFRQPQWQL-----LDPNATATSWSEADTEPCVDGWVYDRSV 123
+ + + G + PH CRR+R L+P + + E C+DGW + + V
Sbjct: 67 -VPLRLRDG-REVPHSCRRYRLATIANFSALGLEPGRDV-DLGQLEQESCLDGWEFSQDV 123
Query: 124 FTSTIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYRFGRKPMLSWCCLQLAVA 183
+ STIV +W+LVC PL+ S+F G+L+GSFI G LS RFGRK +L
Sbjct: 124 YLSTIVTEWNLVCEDDWKAPLTISLFFVGVLLGSFISGQLSDRFGRKNVLFVTMGMQTGF 183
Query: 184 GTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVVGCAFSA-GQ 242
IF+ F ++ L + G ++++ L E S R + T+ C F A G
Sbjct: 184 SFLQIFSKNFEMFVVLFVLVGMGQISNYVAAFVLGTEILGKSVRIIFSTLGVCIFYAFGY 243
Query: 243 AALGGLAFALRDWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQELRKVARI 302
L A+ +RDWR L +A ++P + W++PES RWLI +G+ ++A +RK A+
Sbjct: 244 MVLPLFAYFIRDWRMLLVALTMPGVLCVALWWFIPESPRWLISQGRFEEAEVIIRKAAKA 303
Query: 303 NGHKEAKNLTIEVLMSSVKEEVASAKEPRSVLDLFCVPVLRWRSCAMLVVNFSLLISYYG 362
NG + S +++ + ++ ++LDL +R + +++ ++ + Y+G
Sbjct: 304 NGIVVPSTIFDP---SELQDLSSKKQQSHNILDLLRTWNIRMVTIMSIMLWMTISVGYFG 360
Query: 363 LVFDLQSLGRDIFLLQALFGAVDFLGRATTALLLSFLGRRTIQAGSQAMAGLAILANMLV 422
L D +L DIF+ L V+ LLL +L RR A + + G +L LV
Sbjct: 361 LSLDTPNLHGDIFVNCFLSAMVEVPAYVLAWLLLQYLPRRYSMATALFLGGSVLLFMQLV 420
Query: 423 PQDLQTLRVVFAVLGKGCFGISLTCLTIYKAELFPTPVRMTADGILHTVGRLGAMMGPLI 482
P DL L V ++GK + + + +Y AEL+PT VR G+ T RLG+++ P
Sbjct: 421 PPDLYYLATVLVMVGKFGVTAAFSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYF 480
Query: 483 LMSRQALPLLPPLLYGVISIASSLVVLFFLPETQGLPLPDTIQDL 527
+ LP +L G ++I ++++ L FLPE+ G PLPDTI +
Sbjct: 481 VYLGAYDRFLPYILMGSLTILTAILTL-FLPESFGTPLPDTIDQM 524
>gi|4506999 solute carrier family 22 member 1 isoform a [Homo
sapiens]
Length = 554
Score = 211 bits (538), Expect = 1e-54
Identities = 161/533 (30%), Positives = 257/533 (48%), Gaps = 18/533 (3%)
Query: 6 LLEQAGGVGLFQTLQVLTFILPCLMIPSQMLLENFSAAIPGHRCWTHMLDNGSAVSTNMT 65
+LEQ G G FQ L L + F P H C + + S +
Sbjct: 7 ILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQ-RCGWS 65
Query: 66 PKALLTISIP---PGPNQGPHQCRRFR----QPQWQLLDPNAT-ATSWSEADTEPCVDGW 117
P L ++P P QCRR+ Q +DP A+ AT+ S PC DGW
Sbjct: 66 PAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGPCQDGW 125
Query: 118 VYDRSVFTSTIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYRFGRKPMLSWCC 177
VYD S+IV +++LVC+ L QS +G L GS G + RFGRK L
Sbjct: 126 VYDTP--GSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLLGTV 183
Query: 178 LQLAVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVVGCA 237
L AV+G F+P ++ R + G +++ TL+ E+ + R + A
Sbjct: 184 LVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMYQMA 243
Query: 238 FSAGQAALGGLAFALRDWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQELR 297
F+ G AL GLA+AL WR LQLA S+P F L W +PES RWL+ + + +A++ +
Sbjct: 244 FTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKIMD 303
Query: 298 KVARINGHKEAKNLTIEVLMSSVKEEVASAKEPRSVLDLFCVPVLRWRSCAMLVVNFSLL 357
+A+ NG K ++ M S++E+V P S DLF P LR R+ ++ + F+
Sbjct: 304 HIAQKNG----KLPPADLKMLSLEEDVTEKLSP-SFADLFRTPRLRKRTFILMYLWFTDS 358
Query: 358 ISYYGLVFDLQSLGRDIFLLQALFGAVDFLGRATTALLLSFLGRRTIQAGSQAMAGLAIL 417
+ Y GL+ + + +++L V+ G + + +GR A S +AG A L
Sbjct: 359 VLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACL 418
Query: 418 ANMLVPQDLQTLRVVFAVLGKGCFGISLTCLTIYKAELFPTPVRMTADGILHTVGRLGAM 477
+ + DL L ++ +G+ I++ + + AEL+PT VR + ++ +G +
Sbjct: 419 VMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSSLCDIGGI 478
Query: 478 MGPLILMS-RQALPLLPPLLYGVISIASSLVVLFFLPETQGLPLPDTIQDLES 529
+ P I+ R+ LP +L+ V+ + ++ V L LPET+G+ LP+T++D E+
Sbjct: 479 ITPFIVFRLREVWQALPLILFAVLGLLAAGVTL-LLPETKGVALPETMKDAEN 530
>gi|11415038 solute carrier family 22 member 3 [Homo sapiens]
Length = 556
Score = 208 bits (530), Expect = 9e-54
Identities = 139/434 (32%), Positives = 232/434 (53%), Gaps = 14/434 (3%)
Query: 97 DPNATATSWSEADTEPCVDGWVYDRSVFTSTIVAKWDLVCSSQGLKPLSQSIFMSGILVG 156
DP A + S A PC GW Y ++ STIV+++DLVC + + L+Q+I G L G
Sbjct: 112 DPLAAFPNRS-APLVPCRGGWRYAQA--HSTIVSEFDLVCVNAWMLDLTQAILNLGFLTG 168
Query: 157 SFIWGLLSYRFGRKPMLSWCCLQLAVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLT 216
+F G + R+GR + CL + V G FAP F ++ RF+ G +++
Sbjct: 169 AFTLGYAADRYGRIVIYLLSCLGVGVTGVVVAFAPNFPVFVIFRFLQGVFGKGTWMTCYV 228
Query: 217 LMVEWTTTSRRAVTMTVVGCAFSAGQAALGGLAFALRDWRTLQLAASVPFFAISLISWWL 276
++ E + +R + V+ F+ G L G+A+ + +W+ +QLA ++P F L W +
Sbjct: 229 IVTEIVGSKQRRIVGIVIQMFFTLGIIILPGIAYFIPNWQGIQLAITLPSFLFLLYYWVV 288
Query: 277 PESARWLIIKGKPDQALQELRKVARINGHKEAKNLTIEVLMSSVKEEVASAKEPRSVLDL 336
PES RWLI + K D+ALQ LR++A+ NG + N + E+ ++ EEV++ S LDL
Sbjct: 289 PESPRWLITRKKGDKALQILRRIAKCNGKYLSSNYS-EITVTD--EEVSNP----SFLDL 341
Query: 337 FCVPVLRWRSCAMLVVNFSLLISYYGLVFDLQSLGRDIFLLQALFGAVDFLGRATTALLL 396
P +R + ++ F+ + Y GLV L +G ++++ + G V+ G L +
Sbjct: 342 VRTPQMRKCTLILMFAWFTSAVVYQGLVMRLGIIGGNLYIDFFISGVVELPGALLILLTI 401
Query: 397 SFLGRRTIQAGSQAMAGLAILANMLVPQDLQTLRVVFAVLGKGCFGISLTCLTIYKAELF 456
LGRR A S +AG+A L +P+ + LR A LG+ ++ + + +EL+
Sbjct: 402 ERLGRRLPFAASNIVAGVACLVTAFLPEGIAWLRTTVATLGRLGITMAFEIVYLVNSELY 461
Query: 457 PTPVRMTADGILHTVGRLGAMMGPLILMSRQALPL-LPPLLYGVI-SIASSLVVLFFLPE 514
PT +R + + G ++ P +L A+ L LP +++G++ SI LV+L LPE
Sbjct: 462 PTTLRNFGVSLCSGLCDFGGIIAPFLLFRLAAVWLELPLIIFGILASICGGLVML--LPE 519
Query: 515 TQGLPLPDTIQDLE 528
T+G+ LP+T+ D+E
Sbjct: 520 TKGIALPETVDDVE 533
>gi|4507001 solute carrier family 22 member 2 [Homo sapiens]
Length = 555
Score = 207 bits (527), Expect = 2e-53
Identities = 151/501 (30%), Positives = 247/501 (49%), Gaps = 18/501 (3%)
Query: 40 FSAAIPGHRCWTHMLDNGSAVSTNMTPKALLTISIP-PGP--NQGPHQCRRFR----QPQ 92
F P HRC + + S + +P L ++P PGP P QCRR+ Q
Sbjct: 42 FLGFTPDHRCRSPGVAELS-LRCGWSPAEELNYTVPGPGPAGEASPRQCRRYEVDWNQST 100
Query: 93 WQLLDPNATA-TSWSEADTEPCVDGWVYDRSVFTSTIVAKWDLVCSSQGLKPLSQSIFMS 151
+ +DP A+ T+ S PC DGWVY+ S+IV +++LVC++ + L QS
Sbjct: 101 FDCVDPLASLDTNRSRLPLGPCRDGWVYETP--GSSIVTEFNLVCANSWMLDLFQSSVNV 158
Query: 152 GILVGSFIWGLLSYRFGRKPMLSWCCLQLAVAGTSTIFAPTFVIYCGLRFVAAFGMAGIF 211
G +GS G ++ RFGRK L L A AG +PT+ R + +
Sbjct: 159 GFFIGSMSIGYIADRFGRKLCLLTTVLINAAAGVLMAISPTYTWMLIFRLIQGLVSKAGW 218
Query: 212 LSSLTLMVEWTTTSRRAVTMTVVGCAFSAGQAALGGLAFALRDWRTLQLAASVPFFAISL 271
L L+ E+ R A++ G L G+A+AL WR LQ ++P F L
Sbjct: 219 LIGYILITEFVGRRYRRTVGIFYQVAYTVGLLVLAGVAYALPHWRWLQFTVALPNFFFLL 278
Query: 272 ISWWLPESARWLIIKGKPDQALQELRKVARINGHKEAKNLTIEVLMSSVKEEVASAKEPR 331
W +PES RWLI + K +A++ ++ +A+ NG K+L + ++EE P
Sbjct: 279 YYWCIPESPRWLISQNKNAEAMRIIKHIAKKNG----KSLPASLQRLRLEEETGKKLNP- 333
Query: 332 SVLDLFCVPVLRWRSCAMLVVNFSLLISYYGLVFDLQSLGRDIFLLQALFGAVDFLGRAT 391
S LDL P +R + ++ F+ + Y GL+ + G +I+L V+F
Sbjct: 334 SFLDLVRTPQIRKHTMILMYNWFTSSVLYQGLIMHMGLAGDNIYLDFFYSALVEFPAAFM 393
Query: 392 TALLLSFLGRRTIQAGSQAMAGLAILANMLVPQDLQTLRVVFAVLGKGCFGISLTCLTIY 451
L + +GRR A S +AG A LA++ +P DLQ L+++ + LG+ ++ + +
Sbjct: 394 IILTIDRIGRRYPWAASNMVAGAACLASVFIPGDLQWLKIIISCLGRMGITMAYEIVCLV 453
Query: 452 KAELFPTPVRMTADGILHTVGRLGAMMGPLILMSRQALPL-LPPLLYGVISIASSLVVLF 510
AEL+PT +R I ++ +G ++ P ++ + L LP +++GV+ + + +VL
Sbjct: 454 NAELYPTFIRNLGVHICSSMCDIGGIITPFLVYRLTNIWLELPLMVFGVLGLVAGGLVL- 512
Query: 511 FLPETQGLPLPDTIQDLESQK 531
LPET+G LP+TI++ E+ +
Sbjct: 513 LLPETKGKALPETIEEAENMQ 533
>gi|24497490 solute carrier family 22 member 4 [Homo sapiens]
Length = 551
Score = 206 bits (523), Expect = 6e-53
Identities = 161/544 (29%), Positives = 260/544 (47%), Gaps = 36/544 (6%)
Query: 3 FSKLLEQAGGVGLFQTLQVLTFILPCLMIPSQM--LLENFSAAIPGHRCWTHMLDN-GSA 59
+ +++ G G FQ L + F+L +IP+ + F A P HRC N SA
Sbjct: 4 YDEVIAFLGEWGPFQRL--IFFLLSASIIPNGFNGMSVVFLAGTPEHRCRVPDAANLSSA 61
Query: 60 VSTNMTPKALLTISIPPGPNQGPHQCRRFRQPQWQL-----LDPNATATSWSEADTEPCV 114
N P L + PH C R+R L+P + + E C+
Sbjct: 62 WRNNSVPLRLRD------GREVPHSCSRYRLATIANFSALGLEPGRDV-DLGQLEQESCL 114
Query: 115 DGWVYDRSVFTSTIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYRFGRKPMLS 174
DGW + + V+ ST+V +W+LVC PL+ S+F G+L+GSF+ G LS RFGRK +L
Sbjct: 115 DGWEFSQDVYLSTVVTEWNLVCEDNWKVPLTTSLFFVGVLLGSFVSGQLSDRFGRKNVLF 174
Query: 175 WCCLQLAVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVV 234
IF+ ++ ++ L + G ++ + L E S R + T+
Sbjct: 175 ATMAVQTGFSFLQIFSISWEMFTVLFVIVGMGQISNYVVAFILGTEILGKSVRIIFSTLG 234
Query: 235 GCAFSA-GQAALGGLAFALRDWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQAL 293
C F A G L A+ +RDWR L LA +VP + W++PES RWLI + + +A
Sbjct: 235 VCTFFAVGYMLLPLFAYFIRDWRMLLLALTVPGVLCVPLWWFIPESPRWLISQRRFREAE 294
Query: 294 QELRKVARINGHKEAKNLTIEVLMSSVKEEVASAKEPRS-VLDLFCVPVLRWRSCAMLVV 352
++K A++N N+ + ++ EE+ K+ ++ +LDLF R R+ A++ +
Sbjct: 295 DIIQKAAKMN------NIAVPAVIFDSVEELNPLKQQKAFILDLF-----RTRNIAIMTI 343
Query: 353 NFSLL-----ISYYGLVFDLQSLGRDIFLLQALFGAVDFLGRATTALLLSFLGRRTIQAG 407
LL + Y+ L D +L D +L L ++ T LLL L RR I A
Sbjct: 344 MSLLLWMLTSVGYFALSLDAPNLHGDAYLNCFLSALIEIPAYITAWLLLRTLPRRYIIAA 403
Query: 408 SQAMAGLAILANMLVPQDLQTLRVVFAVLGKGCFGISLTCLTIYKAELFPTPVRMTADGI 467
G +L LVP D L + +LGK + + L ++ AEL+PT VR A G+
Sbjct: 404 VLFWGGGVLLFIQLVPVDYYFLSIGLVMLGKFGITSAFSMLYVFTAELYPTLVRNMAVGV 463
Query: 468 LHTVGRLGAMMGPLILMSRQALPLLPPLLYGVISIASSLVVLFFLPETQGLPLPDTIQDL 527
T R+G+++ P + +LP ++ G +++ ++ LFF PE+ G+ LP+T++ +
Sbjct: 464 TSTASRVGSIIAPYFVYLGAYNRMLPYIVMGSLTVLIGILTLFF-PESLGMTLPETLEQM 522
Query: 528 ESQK 531
+ K
Sbjct: 523 QKVK 526
>gi|157426885 organic cation transporter like 4 [Homo sapiens]
Length = 594
Score = 183 bits (465), Expect = 3e-46
Identities = 149/538 (27%), Positives = 245/538 (45%), Gaps = 34/538 (6%)
Query: 3 FSKLLEQAGGVGLFQTLQVLTFILPCLMIPSQMLLENFSAAIPGHRCWTHMLDNGSAVST 62
F+ LL+ G G FQ V +P +M M ++F C T + AV
Sbjct: 52 FANLLDAVGEFGTFQQRLVALTFIPSIMSAFFMFADHFVFTAQKPYCNTSWI---LAVGP 108
Query: 63 NMTPKALLTISIPPGPNQGPHQCRRFRQPQWQLLDPNATATSWSEADTEPCVDGWVYDRS 122
+++ L ++IP PN C + W L + + DT+ C DGW+Y +
Sbjct: 109 HLSKAEQLNLTIPQAPNGSFLTCFMYLPVPWNL----DSIIQFGLNDTDTCQDGWIYPDA 164
Query: 123 VFTSTIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYRFGRKPMLSWCCLQLAV 182
S ++ ++DLVC + K +Q +FM+G+ +GS I+ L++ + GR P + L L +
Sbjct: 165 KKRS-LINEFDLVCGMETKKDTAQIMFMAGLPIGSLIFRLITDKMGRYPAILLSLLGLII 223
Query: 183 AGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVVGCAFSAGQ 242
G T F +F +Y RF + + G +SS++L EW RA + + C F+ G
Sbjct: 224 FGFGTAFMNSFHLYLFFRFGISQSVVGYAISSISLATEWLVGEHRAHAIILGHCFFAVGA 283
Query: 243 AALGGLAFALRDWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQELRKVARI 302
L G+A++L W+ L L + W LPES RWL++KGK +A Q L A +
Sbjct: 284 VLLTGIAYSLPHWQLLFLVGGILVIPFISYIWILPESPRWLMMKGKVKEAKQVLCYAASV 343
Query: 303 NGHKEAKNLTIEVLMSSVKEEVASAKEPRSVLDLFCVPVLRWRSCAMLVVNFSLLISYYG 362
N NL E+ + K A SVLD L + M V F++ +Y+
Sbjct: 344 NKKTIPSNLLDELQLPRKKVTRA------SVLDFCKNRQLCKVTLVMSCVWFTVSYTYFT 397
Query: 363 LVFDLQSLGRDIFLLQALFGAVDFLGRATTALLLSFLGRRTIQAGSQAMAGLAILANMLV 422
L ++ LG + + ++ R LL +GR+ A + A + L + +
Sbjct: 398 LSLRMRELGVSVHFRHVVPSIMEVPARLCCIFLLQQIGRKWSLAVTLLQAIIWCLLLLFL 457
Query: 423 PQ---------------DLQTLRVVFAVLGKGCFGISLTCLTIYKAELFPTPVRMTADGI 467
P+ +L+++ ++ +L + ++T +Y AEL PT +R T G+
Sbjct: 458 PEGEDGLRLKWPRCPATELKSMTILVLMLREFSLAATVTVFFLYTAELLPTVLRATGLGL 517
Query: 468 LHTVGRLGAMMGPLILMSRQALPLLPPLLYGVISI-ASSLVVLFFLPETQGLPLPDTI 524
+ GA++ I+ Q LLP L V++I A SL L LPET+ PL +++
Sbjct: 518 VSLASVAGAILSLTII--SQTPSLLPIFLCCVLAIVAFSLSSL--LPETRDQPLSESL 571
>gi|23510410 solute carrier family 22 member 1 isoform b [Homo
sapiens]
Length = 506
Score = 180 bits (457), Expect = 3e-45
Identities = 139/461 (30%), Positives = 215/461 (46%), Gaps = 16/461 (3%)
Query: 6 LLEQAGGVGLFQTLQVLTFILPCLMIPSQMLLENFSAAIPGHRCWTHMLDNGSAVSTNMT 65
+LEQ G G FQ L L + F P H C + + S +
Sbjct: 7 ILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQ-RCGWS 65
Query: 66 PKALLTISIP---PGPNQGPHQCRRFR----QPQWQLLDPNAT-ATSWSEADTEPCVDGW 117
P L ++P P QCRR+ Q +DP A+ AT+ S PC DGW
Sbjct: 66 PAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGPCQDGW 125
Query: 118 VYDRSVFTSTIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYRFGRKPMLSWCC 177
VYD S+IV +++LVC+ L QS +G L GS G + RFGRK L
Sbjct: 126 VYDTP--GSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLLGTV 183
Query: 178 LQLAVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVVGCA 237
L AV+G F+P ++ R + G +++ TL+ E+ + R + A
Sbjct: 184 LVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMYQMA 243
Query: 238 FSAGQAALGGLAFALRDWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQELR 297
F+ G AL GLA+AL WR LQLA S+P F L W +PES RWL+ + + +A++ +
Sbjct: 244 FTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKIMD 303
Query: 298 KVARINGHKEAKNLTIEVLMSSVKEEVASAKEPRSVLDLFCVPVLRWRSCAMLVVNFSLL 357
+A+ NG K ++ M S++E+V P S DLF P LR R+ ++ + F+
Sbjct: 304 HIAQKNG----KLPPADLKMLSLEEDVTEKLSP-SFADLFRTPRLRKRTFILMYLWFTDS 358
Query: 358 ISYYGLVFDLQSLGRDIFLLQALFGAVDFLGRATTALLLSFLGRRTIQAGSQAMAGLAIL 417
+ Y GL+ + + +++L V+ G + + +GR A S +AG A L
Sbjct: 359 VLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACL 418
Query: 418 ANMLVPQDLQTLRVVFAVLGKGCFGISLTCLTIYKAELFPT 458
+ + DL L ++ +G+ I++ + + AEL+PT
Sbjct: 419 VMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPT 459
>gi|31542327 solute carrier family 22, member 16 [Homo sapiens]
Length = 577
Score = 165 bits (418), Expect = 9e-41
Identities = 139/569 (24%), Positives = 247/569 (43%), Gaps = 33/569 (5%)
Query: 3 FSKLLEQAGGVGLFQTLQVLTFILPCLMIPSQMLLENFSAAIPGHRC------------- 49
F + + G G FQ + + L F P H C
Sbjct: 6 FEGIYDHVGHFGRFQRVLYFICAFQNISCGIHYLASVFMGVTPHHVCRPPGNVSQVVFHN 65
Query: 50 ---WTHMLDNGSAVSTNMTPKALLTISIPPGPNQGPHQCRRFRQPQWQLLDPNATATSWS 106
W+ + D G+ +S+ K +T+ + G +C R ++ L T +
Sbjct: 66 HSNWS-LEDTGALLSSGQ--KDYVTVQLQNGEIWELSRCSRNKRENTSSLGYEYTGSK-- 120
Query: 107 EADTEPCVDGWVYDRSVFTSTIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYR 166
PCVDG++YD++ + ST V +W+LVC + L L Q +FM G+L+GS +G S R
Sbjct: 121 --KEFPCVDGYIYDQNTWKSTAVTQWNLVCDRKWLAMLIQPLFMFGVLLGSVTFGYFSDR 178
Query: 167 FGRKPMLSWCCLQLAVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSR 226
GR+ +L + + G + FA + + RF A +G + ++E+
Sbjct: 179 LGRRVVLWATSSSMFLFGIAAAFAVDYYTFMAARFFLAMVASGYLVVGFVYVMEFIGMKS 238
Query: 227 RAVTMTVVGCAFSAGQAALGGLAFALRDWRTLQLAASVPFFAISLISWWLPESARWLIIK 286
R + F+ G + + +R W Q+ S L W LPE+ WL+ +
Sbjct: 239 RTWASVHLHSFFAVGTLLVALTGYLVRTWWLYQMILSTVTVPFILCCWVLPETPFWLLSE 298
Query: 287 GKPDQALQELRKVARINGHKEAK-----NLTIEVLMSSVKEEVASAKEPRSVLDLFCVPV 341
G+ ++A + + +A+ N K +L ++ +S+ EV + ++ LF
Sbjct: 299 GRYEEAQKIVDIMAKWNRASSCKLSELLSLDLQGPVSNSPTEV----QKHNLSYLFYNWS 354
Query: 342 LRWRSCAMLVVNFSLLISYYGLVFDLQSLGRDIFLLQALFGAVDFLGRATTALLLSFLGR 401
+ R+ + ++ F+ + +Y + +LG + +L L G V+ + + +GR
Sbjct: 355 ITKRTLTVWLIWFTGSLGFYSFSLNSVNLGGNEYLNLFLLGVVEIPAYTFVCIAMDKVGR 414
Query: 402 RTIQAGSQAMAGLAILANMLVPQDLQTLRVVFAVLGKGCFGISLTCLTIYKAELFPTPVR 461
RT+ A S + LA M++PQ L VV A++GK G + + +Y AEL+PT VR
Sbjct: 415 RTVLAYSLFCSALACGVVMVIPQKHYILGVVTAMVGKFAIGAAFGLIYLYTAELYPTIVR 474
Query: 462 MTADGILHTVGRLGAMMGPLILMSRQALPLLPPLLYGVISIASSLVVLFFLPETQGLPLP 521
A G V RL +++ P + +P L G +++ S ++ L LPET G L
Sbjct: 475 SLAVGSGSMVCRLASILAPFSVDLSSIWIFIPQLFVGTMALLSGVLTL-KLPETLGKRLA 533
Query: 522 DTIQDLESQKSTAAQGNRQEAVTVESTSL 550
T ++ +S + + +T ++ L
Sbjct: 534 TTWEEAAKLESENESKSSKLLLTTNNSGL 562
>gi|166197673 solute carrier family 22, member 15 [Homo sapiens]
Length = 547
Score = 157 bits (397), Expect = 2e-38
Identities = 123/422 (29%), Positives = 199/422 (47%), Gaps = 23/422 (5%)
Query: 118 VYDRSVFTSTIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYRFGRKPM-LSWC 176
V+ S FTS I ++W L+ + + S F SG+ VG +G LS RFGRK + L+
Sbjct: 88 VHFSSSFTS-IASEWFLIANRSYKVSAASSFFFSGVFVGVISFGQLSDRFGRKKVYLTGF 146
Query: 177 CLQLAVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVVGC 236
L + A + F+P++ + RF+ G+ L + L+ E T+ A+ ++ G
Sbjct: 147 ALDILFA-IANGFSPSYEFFAVTRFLVGMMNGGMSLVAFVLLNECVGTAYWALAGSIGGL 205
Query: 237 AFSAGQAALGGLAFALRDWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQEL 296
F+ G A L + +R WRTL + ++ + L+S ++PES RWL +G+ +A + L
Sbjct: 206 FFAVGIAQYALLGYFIRSWRTLAILVNLQGTVVFLLSLFIPESPRWLYSQGRLSEAEEAL 265
Query: 297 RKVARINGHKEAKNLTIEVLMSSVKEEVASAKEPRSVLDLFCVPVLRWRSCAMLVVNFSL 356
+A+ +N ++ S S +E S LDLF VL + ++ + F
Sbjct: 266 YLIAK-------RNRKLKCTFSLTHPANRSCRETGSFLDLFRYRVLLGHTLILMFIWFVC 318
Query: 357 LISYYGLVFDLQSLGRDIFLLQALFGAVDFLGRATTALLLS--FLGRRTIQAGSQAMAGL 414
+ YYGL LG I+ AL G ++ L++ + GR+ + + GL
Sbjct: 319 SLVYYGLTLSAGDLGGSIYANLALSGLIEIPSYPLCIYLINQKWFGRKRTLSAFLCLGGL 378
Query: 415 AILANMLVPQDLQTLRVVFAV--------LGKGCFGISLTCLTIYKAELFPTPVRMTADG 466
A L M +P+ T VFAV LGK + + IY +EL+PT +R G
Sbjct: 379 ACLIVMFLPEKKDT--GVFAVVNSHSLSLLGKLTISAAFNIVYIYTSELYPTVIRNVGLG 436
Query: 467 ILHTVGRLGAMMGPLILMSRQALPLLPPLLYGVISIASSLVVLFFLPETQGLPLPDTIQD 526
R+G ++ P I + LP +++G + S L+ L LPET PL +T D
Sbjct: 437 TCSMFSRVGGIIAPFIPSLKYVQWSLPFIVFGATGLTSGLLSL-LLPETLNSPLLETFSD 495
Query: 527 LE 528
L+
Sbjct: 496 LQ 497
>gi|169202895 PREDICTED: similar to solute carrier family 22, member
24 [Homo sapiens]
Length = 139
Score = 116 bits (290), Expect = 6e-26
Identities = 63/133 (47%), Positives = 80/133 (60%), Gaps = 5/133 (3%)
Query: 1 MAFSKLLEQAGGVGLFQTLQVLTFILPCLMIPSQMLLENFSAAIPGHRCWTHMLDNGSAV 60
M F LL+Q GG+G FQ ++ + ++ +LLENF A IPGH W H+LDN + V
Sbjct: 1 MGFDMLLDQVGGLGRFQIFHLIFLTISIIIHYPHLLLENFIAFIPGHHYWVHILDNDT-V 59
Query: 61 STN----MTPKALLTISIPPGPNQGPHQCRRFRQPQWQLLDPNATATSWSEADTEPCVDG 116
S N ++ ALL ISIP N P +CR F PQW LL N T ++ SE +TEPCV G
Sbjct: 60 SDNDTGTLSQVALLRISIPLDSNLRPEKCRCFIHPQWHLLHLNVTFSNMSEPNTEPCVGG 119
Query: 117 WVYDRSVFTSTIV 129
WVY +S F TIV
Sbjct: 120 WVYHQSSFLFTIV 132
>gi|239750073 PREDICTED: similar to solute carrier family 22, member
24 [Homo sapiens]
Length = 139
Score = 116 bits (290), Expect = 6e-26
Identities = 63/133 (47%), Positives = 80/133 (60%), Gaps = 5/133 (3%)
Query: 1 MAFSKLLEQAGGVGLFQTLQVLTFILPCLMIPSQMLLENFSAAIPGHRCWTHMLDNGSAV 60
M F LL+Q GG+G FQ ++ + ++ +LLENF A IPGH W H+LDN + V
Sbjct: 1 MGFDMLLDQVGGLGRFQIFHLIFLTISIIIHYPHLLLENFIAFIPGHHYWVHILDNDT-V 59
Query: 61 STN----MTPKALLTISIPPGPNQGPHQCRRFRQPQWQLLDPNATATSWSEADTEPCVDG 116
S N ++ ALL ISIP N P +CR F PQW LL N T ++ SE +TEPCV G
Sbjct: 60 SDNDTGTLSQVALLRISIPLDSNLRPEKCRCFIHPQWHLLHLNVTFSNMSEPNTEPCVGG 119
Query: 117 WVYDRSVFTSTIV 129
WVY +S F TIV
Sbjct: 120 WVYHQSSFLFTIV 132
>gi|239744382 PREDICTED: hypothetical protein XP_002343132 [Homo
sapiens]
Length = 139
Score = 116 bits (290), Expect = 6e-26
Identities = 63/133 (47%), Positives = 80/133 (60%), Gaps = 5/133 (3%)
Query: 1 MAFSKLLEQAGGVGLFQTLQVLTFILPCLMIPSQMLLENFSAAIPGHRCWTHMLDNGSAV 60
M F LL+Q GG+G FQ ++ + ++ +LLENF A IPGH W H+LDN + V
Sbjct: 1 MGFDMLLDQVGGLGRFQIFHLIFLTISIIIHYPHLLLENFIAFIPGHHYWVHILDNDT-V 59
Query: 61 STN----MTPKALLTISIPPGPNQGPHQCRRFRQPQWQLLDPNATATSWSEADTEPCVDG 116
S N ++ ALL ISIP N P +CR F PQW LL N T ++ SE +TEPCV G
Sbjct: 60 SDNDTGTLSQVALLRISIPLDSNLRPEKCRCFIHPQWHLLHLNVTFSNMSEPNTEPCVGG 119
Query: 117 WVYDRSVFTSTIV 129
WVY +S F TIV
Sbjct: 120 WVYHQSSFLFTIV 132
>gi|170650643 solute carrier family 22, member 23 isoform a [Homo
sapiens]
Length = 686
Score = 107 bits (267), Expect = 3e-23
Identities = 106/447 (23%), Positives = 194/447 (43%), Gaps = 50/447 (11%)
Query: 117 WVYD-RSVFTSTIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYRFGRKPMLSW 175
W Y R+ +V+KWDLVC + +++ + G++ G I G ++ GR+P+L +
Sbjct: 203 WDYGIRAGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLF 262
Query: 176 CCLQLAVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVVG 235
+ + + G + + ++ LRF F +AGI L+ L +E +R + V
Sbjct: 263 SIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVAS 322
Query: 236 CAFSAGQAALGGLAFALRDWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQE 295
AGQ + GLA RDW+ LQ PF + L PES RWL+ A Q+
Sbjct: 323 FVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLM-------ATQQ 375
Query: 296 LRKVARINGHKEAKNL-----TIEVLMSSVKEEVASAKEPRSVLDLFCVPVLR-WRSCAM 349
R+ H KN I+ ++ +++E+ ++ P+ V + V W++ +
Sbjct: 376 FESAKRLILHFTQKNRMNPEGDIKGVIPELEKEL--SRRPKKVCIVKVVGTRNLWKNIVV 433
Query: 350 LVVNFSLLISYYGL--VFDLQSLGRDIF--LLQALFGAVDFLGRATTAL--------LLS 397
L VN ++ YG+ F +G ++ LL+ + D+ A+ AL ++
Sbjct: 434 LCVN---SLTGYGIHHCFARSMMGHEVKVPLLENFY--ADYYTTASIALVSCLAMCVVVR 488
Query: 398 FLGRRTIQAGSQAMAGLAILANM----LVPQDLQ------------TLRVVFAVLGKGCF 441
FLGRR + LA L + L+ + Q + F+++G
Sbjct: 489 FLGRRGGLLLFMILTALASLLQLGLLNLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFAS 548
Query: 442 GISLTCLTIYKAELFPTPVRMTADGILHTVGRLGAMMGPLILMSRQALPLLPPLLYGVIS 501
+ + AE+ PT +R G++ G + P+I + Q L +++ +
Sbjct: 549 HAVGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCT 608
Query: 502 IASSLVVLFFLPETQGLPLPDTIQDLE 528
+ ++ + LPE++ LP+ I + E
Sbjct: 609 LI-CIICILLLPESRDQNLPENISNGE 634
>gi|239745643 PREDICTED: hypothetical protein LOC146429 isoform 1
[Homo sapiens]
Length = 558
Score = 105 bits (261), Expect = 1e-22
Identities = 137/539 (25%), Positives = 217/539 (40%), Gaps = 34/539 (6%)
Query: 4 SKLLEQAGGVGLFQTLQVLTFILPCLMIPSQMLLENFSAAIPGHRCWTHMLDNGSAVSTN 63
+++L AGG G + L +PC+++ + E A P C A+
Sbjct: 5 ARVLRAAGGFGRARRLLASASWVPCIVLGLVLSSEELLTAQPAPHCRPDPTLLPPALRAL 64
Query: 64 MTPKALLTISIPP-GPNQGPHQCRRFRQPQWQLLDPNATATSWSEADTEPCVDGWVYDRS 122
P ALL +IP GP + P + P + L P A P W S
Sbjct: 65 RGP-ALLDAAIPRLGPTRAPAEALGVLSPSY--LAPLTRA---------PRPSSWA---S 109
Query: 123 VFTSTIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYRFGRKPMLSWCCLQLAV 182
+ W+LVC PL Q + G L+G I G RFGR+ + +
Sbjct: 110 CSGAAAGPTWNLVCGDGWKVPLEQVSHLLGWLLGCVILGAGCDRFGRRAVFVASLVLTTG 169
Query: 183 AGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVVGCAFSAGQ 242
G S A +F LR + +AG L+ +E R G G
Sbjct: 170 LGASEALAASFPTLLVLRLLHGGTLAGALLALYLARLELCDPPHRLAFSMGAGLFSVVGT 229
Query: 243 AALGGLAFALRDWRTLQLAASVPFFAISLISW----WLPESARWLIIKGKPDQALQELRK 298
L GLA ++DWR LQ ++ + L+ W PES WL+ G+ +A + L +
Sbjct: 230 LLLPGLAALVQDWRLLQGLGAL-MSGLLLLFWGFPALFPESPCWLLATGQVARARKILWR 288
Query: 299 VARINGHKEA-KNLTIEVLMSSVKEEVASAKEPR----SVLDLFCVPVLRWRSCAMLVVN 353
A +G +L L ++ + + SA+ P+ S L L V WR+ L++
Sbjct: 289 FAEASGVGPGDSSLEENSLATATELTMLSARSPQPRYHSPLGLLRTRV-TWRN--GLILG 345
Query: 354 FSLLISYYGLVFDLQSLGRDI---FLLQALFGAVDFLGRATTALLLSFLGRRTIQAGSQA 410
FS L+ +SL + +L L ++ L GRR +
Sbjct: 346 FSSLVGGGIRASFRRSLAPQVPTFYLPYFLEAGLEAAALVFLLLTADCCGRRPVLLLGTM 405
Query: 411 MAGLAILANMLVPQDLQTLRVVF-AVLGKGCFGISLTCLTIYKAELFPTPVRMTADGILH 469
+ GLA L + Q L V+F +VLG +++ AE+FPT +R G++
Sbjct: 406 VTGLASLLLLAGAQYLPGWTVLFLSVLGLLASRAVSALSSLFAAEVFPTVIRGAGLGLVL 465
Query: 470 TVGRLGAMMGPLILMSRQALPLLPPLLYGVISIASSLVVLFFLPETQGLPLPDTIQDLE 528
G LG GPL + + L +++ +++ + L VL LPE++ LP ++QD +
Sbjct: 466 GAGFLGQAAGPLDTLHGRQGFFLQQVVFASLAVLALLCVL-LLPESRSRGLPQSLQDAD 523
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.137 0.422
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,170,482
Number of Sequences: 37866
Number of extensions: 813557
Number of successful extensions: 2875
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 46
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 2687
Number of HSP's gapped (non-prelim): 83
length of query: 550
length of database: 18,247,518
effective HSP length: 107
effective length of query: 443
effective length of database: 14,195,856
effective search space: 6288764208
effective search space used: 6288764208
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.