Guide to the Human Genome
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Search of human proteins with 14149999

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14149999 zinc finger, MYND-type containing 15 isoform 2
[Homo sapiens]
         (703 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14149999 zinc finger, MYND-type containing 15 isoform 2 [Homo...  1461   0.0  
gi|209862893 zinc finger, MYND-type containing 15 isoform 1 [Hom...  1440   0.0  
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]           48   4e-05
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]           48   4e-05
gi|21735415 centromere protein B [Homo sapiens]                        47   6e-05
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi...    46   1e-04
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ...    46   1e-04
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ...    46   1e-04
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)...    46   1e-04
gi|10864057 protamine 3 [Homo sapiens]                                 46   1e-04
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    45   2e-04
gi|42476169 Paf1, RNA polymerase II associated factor, homolog [...    45   2e-04
gi|4503257 death-domain associated protein isoform a [Homo sapiens]    45   2e-04
gi|215422388 death-domain associated protein isoform a [Homo sap...    45   2e-04
gi|215422366 death-domain associated protein isoform b [Homo sap...    45   2e-04
gi|218505694 potassium channel tetramerisation domain containing...    45   3e-04
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]     44   4e-04
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]     44   4e-04
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof...    44   4e-04
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof...    44   4e-04
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof...    44   4e-04
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof...    44   4e-04
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof...    44   4e-04
gi|13540523 nucleosomal binding protein 1 [Homo sapiens]               44   5e-04
gi|21735569 claspin [Homo sapiens]                                     44   5e-04
gi|148727368 bromodomain and PHD finger containing, 3 [Homo sapi...    44   5e-04
gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 famil...    44   7e-04
gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens]     43   9e-04
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof...    43   9e-04
gi|4758392 forkhead box D1 [Homo sapiens]                              43   9e-04

>gi|14149999 zinc finger, MYND-type containing 15 isoform 2 [Homo
           sapiens]
          Length = 703

 Score = 1461 bits (3783), Expect = 0.0
 Identities = 703/703 (100%), Positives = 703/703 (100%)

Query: 1   MEFVSGYRDEFLDFTALLFGWFRKFVAERGAVGTSLEGRCRQLEAQIRRLPQDPALWVLH 60
           MEFVSGYRDEFLDFTALLFGWFRKFVAERGAVGTSLEGRCRQLEAQIRRLPQDPALWVLH
Sbjct: 1   MEFVSGYRDEFLDFTALLFGWFRKFVAERGAVGTSLEGRCRQLEAQIRRLPQDPALWVLH 60

Query: 61  VLPNHSVGISLGQGAEPGPGPGLGTAWLLGDNPPLHLRDLSPYISFVSLEDGEEGEEEEE 120
           VLPNHSVGISLGQGAEPGPGPGLGTAWLLGDNPPLHLRDLSPYISFVSLEDGEEGEEEEE
Sbjct: 61  VLPNHSVGISLGQGAEPGPGPGLGTAWLLGDNPPLHLRDLSPYISFVSLEDGEEGEEEEE 120

Query: 121 EDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAAREAGGGKDGCRE 180
           EDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAAREAGGGKDGCRE
Sbjct: 121 EDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAAREAGGGKDGCRE 180

Query: 181 DRVENETRPQKRKGQRSEAAPLHVSCLLLVTDEHGTILGIDLLVDGAQGTASWGSGTKDL 240
           DRVENETRPQKRKGQRSEAAPLHVSCLLLVTDEHGTILGIDLLVDGAQGTASWGSGTKDL
Sbjct: 181 DRVENETRPQKRKGQRSEAAPLHVSCLLLVTDEHGTILGIDLLVDGAQGTASWGSGTKDL 240

Query: 241 APWAYALLCHSMACPMGSGDPRKPRQLTVGDARLHRELESLVPRLGVKLAKTPMRTWGPR 300
           APWAYALLCHSMACPMGSGDPRKPRQLTVGDARLHRELESLVPRLGVKLAKTPMRTWGPR
Sbjct: 241 APWAYALLCHSMACPMGSGDPRKPRQLTVGDARLHRELESLVPRLGVKLAKTPMRTWGPR 300

Query: 301 PGFTFASLRARTCHVCHRHSFEAKLTPCPQCSAVLYCGEACLRADWQRCPDDVSHRFWCP 360
           PGFTFASLRARTCHVCHRHSFEAKLTPCPQCSAVLYCGEACLRADWQRCPDDVSHRFWCP
Sbjct: 301 PGFTFASLRARTCHVCHRHSFEAKLTPCPQCSAVLYCGEACLRADWQRCPDDVSHRFWCP 360

Query: 361 RLAAFMERAGELATLPFTYTAEVTSETFNKEAFLASRGLTRGYWTQLSMLIPGPGFSRHP 420
           RLAAFMERAGELATLPFTYTAEVTSETFNKEAFLASRGLTRGYWTQLSMLIPGPGFSRHP
Sbjct: 361 RLAAFMERAGELATLPFTYTAEVTSETFNKEAFLASRGLTRGYWTQLSMLIPGPGFSRHP 420

Query: 421 RGNTPSLSLLRGGDPYQLLQGDGTALMPPVPPHPPRGVFVPELNIQNKQSLKIHVVEAGK 480
           RGNTPSLSLLRGGDPYQLLQGDGTALMPPVPPHPPRGVFVPELNIQNKQSLKIHVVEAGK
Sbjct: 421 RGNTPSLSLLRGGDPYQLLQGDGTALMPPVPPHPPRGVFVPELNIQNKQSLKIHVVEAGK 480

Query: 481 EFDLVMVFWELLVLLPHVALELQFVGDGLPPESDEQHFTLQRDSLEVSVRPGSGISARPS 540
           EFDLVMVFWELLVLLPHVALELQFVGDGLPPESDEQHFTLQRDSLEVSVRPGSGISARPS
Sbjct: 481 EFDLVMVFWELLVLLPHVALELQFVGDGLPPESDEQHFTLQRDSLEVSVRPGSGISARPS 540

Query: 541 SGTKEKGGRRDLQIKVSARPYHLFQGPKPDLVIGFNSGFALKDTWLRSLPRLQSLRVPAF 600
           SGTKEKGGRRDLQIKVSARPYHLFQGPKPDLVIGFNSGFALKDTWLRSLPRLQSLRVPAF
Sbjct: 541 SGTKEKGGRRDLQIKVSARPYHLFQGPKPDLVIGFNSGFALKDTWLRSLPRLQSLRVPAF 600

Query: 601 FTESSEYSCVMDGQTMAVATGGGTSPPQPNPFRSPFRLRAADNCMSWYCNAFIFHLVYKP 660
           FTESSEYSCVMDGQTMAVATGGGTSPPQPNPFRSPFRLRAADNCMSWYCNAFIFHLVYKP
Sbjct: 601 FTESSEYSCVMDGQTMAVATGGGTSPPQPNPFRSPFRLRAADNCMSWYCNAFIFHLVYKP 660

Query: 661 AQGSGARPAPGPPPPSPTPSAPPAPTRRRRGEKKPGRGARRRK 703
           AQGSGARPAPGPPPPSPTPSAPPAPTRRRRGEKKPGRGARRRK
Sbjct: 661 AQGSGARPAPGPPPPSPTPSAPPAPTRRRRGEKKPGRGARRRK 703


>gi|209862893 zinc finger, MYND-type containing 15 isoform 1 [Homo
           sapiens]
          Length = 742

 Score = 1440 bits (3728), Expect = 0.0
 Identities = 702/742 (94%), Positives = 702/742 (94%), Gaps = 39/742 (5%)

Query: 1   MEFVSGYRDEFLDFTALLFGWFRKFVAERGAVGTSLEGRCRQLEAQIRRLPQDPALWVLH 60
           MEFVSGYRDEFLDFTALLFGWFRKFVAERGAVGTSLEGRCRQLEAQIRRLPQDPALWVLH
Sbjct: 1   MEFVSGYRDEFLDFTALLFGWFRKFVAERGAVGTSLEGRCRQLEAQIRRLPQDPALWVLH 60

Query: 61  VLPNHSVGISLGQGAEPGPGPGLGTAWLLGDNPPLHLRDLSPYISFVSLEDGEEGEEEEE 120
           VLPNHSVGISLGQGAEPGPGPGLGTAWLLGDNPPLHLRDLSPYISFVSLEDGEEGEEEEE
Sbjct: 61  VLPNHSVGISLGQGAEPGPGPGLGTAWLLGDNPPLHLRDLSPYISFVSLEDGEEGEEEEE 120

Query: 121 EDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAAREAGGGKDGCRE 180
           EDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAAREAGGGKDGCRE
Sbjct: 121 EDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAAREAGGGKDGCRE 180

Query: 181 DRVENETRPQKRKGQRSEAAPLHVSCLLLVTDEHGTILGIDLLVDGAQGTASWGSGTKDL 240
           DRVENETRPQKRKGQRSEAAPLHVSCLLLVTDEHGTILGIDLLVDGAQGTASWGSGTKDL
Sbjct: 181 DRVENETRPQKRKGQRSEAAPLHVSCLLLVTDEHGTILGIDLLVDGAQGTASWGSGTKDL 240

Query: 241 APWAYALLCHSMACPMGSGDPRKPRQLTVGDARLHRELESLVPRLGVKLAKTPMRTWGPR 300
           APWAYALLCHSMACPMGSGDPRKPRQLTVGDARLHRELESLVPRLGVKLAKTPMRTWGPR
Sbjct: 241 APWAYALLCHSMACPMGSGDPRKPRQLTVGDARLHRELESLVPRLGVKLAKTPMRTWGPR 300

Query: 301 PGFTFASLRARTCHVCHRHSFEAKLTPCPQCSAVLYCGEACLRADWQRCPDDVSHRFWCP 360
           PGFTFASLRARTCHVCHRHSFEAKLTPCPQCSAVLYCGEACLRADWQRCPDDVSHRFWCP
Sbjct: 301 PGFTFASLRARTCHVCHRHSFEAKLTPCPQCSAVLYCGEACLRADWQRCPDDVSHRFWCP 360

Query: 361 RLAAFMERAGELATLPFTYTAEVTSETFNKEAFLASRGLTRGYWTQLSMLIPGPGFSRHP 420
           RLAAFMERAGELATLPFTYTAEVTSETFNKEAFLASRGLTRGYWTQLSMLIPGPGFSRHP
Sbjct: 361 RLAAFMERAGELATLPFTYTAEVTSETFNKEAFLASRGLTRGYWTQLSMLIPGPGFSRHP 420

Query: 421 RGNTPSLSLLRGGDPYQLLQGDGTALMPPVPPHPPRGVF--------------------- 459
           RGNTPSLSLLRGGDPYQLLQGDGTALMPPVPPHPPRGVF                     
Sbjct: 421 RGNTPSLSLLRGGDPYQLLQGDGTALMPPVPPHPPRGVFGSWQDYYTWRGLSLDSPIAVL 480

Query: 460 ------------------VPELNIQNKQSLKIHVVEAGKEFDLVMVFWELLVLLPHVALE 501
                              PELNIQNKQSLKIHVVEAGKEFDLVMVFWELLVLLPHVALE
Sbjct: 481 LTYPLTVYYVITHLVPQSFPELNIQNKQSLKIHVVEAGKEFDLVMVFWELLVLLPHVALE 540

Query: 502 LQFVGDGLPPESDEQHFTLQRDSLEVSVRPGSGISARPSSGTKEKGGRRDLQIKVSARPY 561
           LQFVGDGLPPESDEQHFTLQRDSLEVSVRPGSGISARPSSGTKEKGGRRDLQIKVSARPY
Sbjct: 541 LQFVGDGLPPESDEQHFTLQRDSLEVSVRPGSGISARPSSGTKEKGGRRDLQIKVSARPY 600

Query: 562 HLFQGPKPDLVIGFNSGFALKDTWLRSLPRLQSLRVPAFFTESSEYSCVMDGQTMAVATG 621
           HLFQGPKPDLVIGFNSGFALKDTWLRSLPRLQSLRVPAFFTESSEYSCVMDGQTMAVATG
Sbjct: 601 HLFQGPKPDLVIGFNSGFALKDTWLRSLPRLQSLRVPAFFTESSEYSCVMDGQTMAVATG 660

Query: 622 GGTSPPQPNPFRSPFRLRAADNCMSWYCNAFIFHLVYKPAQGSGARPAPGPPPPSPTPSA 681
           GGTSPPQPNPFRSPFRLRAADNCMSWYCNAFIFHLVYKPAQGSGARPAPGPPPPSPTPSA
Sbjct: 661 GGTSPPQPNPFRSPFRLRAADNCMSWYCNAFIFHLVYKPAQGSGARPAPGPPPPSPTPSA 720

Query: 682 PPAPTRRRRGEKKPGRGARRRK 703
           PPAPTRRRRGEKKPGRGARRRK
Sbjct: 721 PPAPTRRRRGEKKPGRGARRRK 742


>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
          Length = 709

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 28/77 (36%), Positives = 41/77 (53%), Gaps = 1/77 (1%)

Query: 110 EDGEEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAAR 169
           EDGEE EEEEEE+EEEE+ E+      E+ + EE  +    S  S   +     ++ + R
Sbjct: 227 EDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVR 286

Query: 170 EAGGGKDGCREDRVENE 186
            +G G DG  E + E +
Sbjct: 287 -SGSGTDGSDEKKKERK 302



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 28/105 (26%), Positives = 46/105 (43%), Gaps = 18/105 (17%)

Query: 113 EEGEEEEEEDEEEEKREDGGAGSTE-------------KVEPEEDRELAPTSRESPQETN 159
           +  +EE   +E     E G +GS++             + + EED E+   + E  +E +
Sbjct: 168 QSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEED-EEVD 226

Query: 160 PPGESEEAAREAGGGKDGCREDRVENETRPQKRKGQ----RSEAA 200
             GE EE   E    ++   E+  E + R QK +G     RSEA+
Sbjct: 227 EDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEAS 271


>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
          Length = 727

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 28/77 (36%), Positives = 41/77 (53%), Gaps = 1/77 (1%)

Query: 110 EDGEEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAAR 169
           EDGEE EEEEEE+EEEE+ E+      E+ + EE  +    S  S   +     ++ + R
Sbjct: 227 EDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVR 286

Query: 170 EAGGGKDGCREDRVENE 186
            +G G DG  E + E +
Sbjct: 287 -SGSGTDGSDEKKKERK 302



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 28/105 (26%), Positives = 46/105 (43%), Gaps = 18/105 (17%)

Query: 113 EEGEEEEEEDEEEEKREDGGAGSTE-------------KVEPEEDRELAPTSRESPQETN 159
           +  +EE   +E     E G +GS++             + + EED E+   + E  +E +
Sbjct: 168 QSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEED-EEVD 226

Query: 160 PPGESEEAAREAGGGKDGCREDRVENETRPQKRKGQ----RSEAA 200
             GE EE   E    ++   E+  E + R QK +G     RSEA+
Sbjct: 227 EDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEAS 271


>gi|21735415 centromere protein B [Homo sapiens]
          Length = 599

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 32/81 (39%), Positives = 46/81 (56%), Gaps = 9/81 (11%)

Query: 110 EDGEEGEEEEEEDEEEEKREDGG----AGSTEKVEPEEDRELAPTSRESPQETNPPGESE 165
           E+ EEGE EEEE+E EE+ E+GG     G  E+VE E D +      E  + ++   E+E
Sbjct: 415 EEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAE 474

Query: 166 EAAR---EAGG--GKDGCRED 181
           + A+   EAGG  G  G +E+
Sbjct: 475 DWAQGVVEAGGSFGAYGAQEE 495



 Score = 43.1 bits (100), Expect = 9e-04
 Identities = 30/74 (40%), Positives = 37/74 (50%), Gaps = 11/74 (14%)

Query: 114 EGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAAREAGG 173
           EGEEEEEE+EEEE+ E  G G  E+ E EE+ E      E        GE EE   E  G
Sbjct: 404 EGEEEEEEEEEEEEEE--GEGEEEEEEGEEEEEEGGEGEEL-------GEEEEVEEE--G 452

Query: 174 GKDGCREDRVENET 187
             D   E+  + E+
Sbjct: 453 DVDSDEEEEEDEES 466


>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
           sapiens]
          Length = 1341

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 32/98 (32%), Positives = 48/98 (48%), Gaps = 5/98 (5%)

Query: 110 EDGEEGEEEEEEDEEEEKREDGGAGSTE----KVEPEEDRELAPTSRESPQETNPPGES- 164
           E+ EE EEEEEED+EEE+ +D G  S E    K   EE  E+     E   +  P   S 
Sbjct: 270 EEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRVKPEEMMDERPKTRSQ 329

Query: 165 EEAAREAGGGKDGCREDRVENETRPQKRKGQRSEAAPL 202
           E+   E GG     +E+  ++    Q+++ +    +PL
Sbjct: 330 EQEVLERGGRFTRSQEEARKSHLARQQQEKEMKTTSPL 367



 Score = 34.3 bits (77), Expect = 0.41
 Identities = 27/94 (28%), Positives = 42/94 (44%), Gaps = 3/94 (3%)

Query: 110  EDGEEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAAR 169
            E  +E E+  +E EEEE++E       E+    E  +    SRE  +E     E +   R
Sbjct: 1243 ERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDR 1302

Query: 170  EAGGGKDGCREDRVENETRPQKRKGQ-RSEAAPL 202
            +    +D  RE   E + R  KR  + RS + P+
Sbjct: 1303 DRDRERD--RERGRERDRRDTKRHSRSRSRSTPV 1334



 Score = 30.4 bits (67), Expect = 5.9
 Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 1/91 (1%)

Query: 109 LEDGEEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGE-SEEA 167
           L +G +  EEEE+ E   +     A    K E EE+ E      +  +E +  G+ S EA
Sbjct: 239 LSEGSQPAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREA 298

Query: 168 AREAGGGKDGCREDRVENETRPQKRKGQRSE 198
                  ++G    RV+ E    +R   RS+
Sbjct: 299 PILKEFKEEGEEIPRVKPEEMMDERPKTRSQ 329



 Score = 30.0 bits (66), Expect = 7.6
 Identities = 31/118 (26%), Positives = 50/118 (42%), Gaps = 17/118 (14%)

Query: 91   DNPPLHLRD-------LSPYISFVSLEDGE----EGEEEEEEDEEEEKREDGGAGSTEKV 139
            + PP  L D        +P I ++ L D +    E E  E   E E++R++      ++ 
Sbjct: 1204 EEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKRRKEQEEEEQKER 1263

Query: 140  EPEEDREL-APTSRESPQETNPPGESEEAAREAGGGKDGCREDRVENETRPQKRKGQR 196
            E E +RE      RE  +E      S E  RE    ++  R DR  +  R ++R  +R
Sbjct: 1264 EKEAERERNRQLEREKRRE-----HSRERDRERERERERDRGDRDRDRERDRERGRER 1316


>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
           [Homo sapiens]
          Length = 916

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 28/75 (37%), Positives = 39/75 (52%), Gaps = 5/75 (6%)

Query: 113 EEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAAREAG 172
           EEGE+EEEE +EEE+ ED GA S +  E   ++E +    E  QE     E E  A   G
Sbjct: 523 EEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQE-----EGETEAEAEG 577

Query: 173 GGKDGCREDRVENET 187
              +   E +VE ++
Sbjct: 578 EEAEAKEEKKVEEKS 592



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 28/94 (29%), Positives = 42/94 (44%), Gaps = 5/94 (5%)

Query: 110 EDGEEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAAR 169
           E  EE EEE E +EEE   +     +T     EE+ E      +  +E    G   + A 
Sbjct: 490 EAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAE 549

Query: 170 EAGGGKDGCRE----DRVENETRPQKRKGQRSEA 199
           E G  K+G  E    ++ E ET  +  +G+ +EA
Sbjct: 550 EGGSEKEGSSEKEEGEQEEGETEAE-AEGEEAEA 582



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 25/89 (28%), Positives = 39/89 (43%), Gaps = 6/89 (6%)

Query: 110 EDGEEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAAR 169
           E+ +E  EE+EE+ E E+ E     S  K    E +E      E  ++    G+ EE   
Sbjct: 486 EEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKE------EEGEKEEEEGQEEEEEE 539

Query: 170 EAGGGKDGCREDRVENETRPQKRKGQRSE 198
           + G   D   E   E E   +K +G++ E
Sbjct: 540 DEGAKSDQAEEGGSEKEGSSEKEEGEQEE 568



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 32/98 (32%), Positives = 50/98 (51%), Gaps = 14/98 (14%)

Query: 107 VSLEDGEEGEEEEEEDEEEE-------KREDGGA---GSTEKVEPE-EDRELAPTSRESP 155
           V  E+GE+ EEE +E+EEEE       + E+GG+   GS+EK E E E+ E    +    
Sbjct: 520 VKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEE 579

Query: 156 QETNPPGESEEAAREAGGGKDGCREDRVENETRPQKRK 193
            E     + EE + E    ++   + +VE   +P+K K
Sbjct: 580 AEAKEEKKVEEKSEEVATKEELVADAKVE---KPEKAK 614



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 26/112 (23%), Positives = 51/112 (45%), Gaps = 11/112 (9%)

Query: 110 EDGEEGEEEEEEDEEEEKREDGGA---GSTEKVEPEEDRELAPTSRESPQETNPPGESEE 166
           E  EEG+  ++E E+E+   +GG+   GS +  +     ++A       +E     E E+
Sbjct: 760 ETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKE-----EVEQ 814

Query: 167 AAREAGGGKD---GCREDRVENETRPQKRKGQRSEAAPLHVSCLLLVTDEHG 215
             +E G G++   G   + ++     +K+ G +SE   +    +  +T E G
Sbjct: 815 ETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITSEGG 866



 Score = 30.8 bits (68), Expect = 4.5
 Identities = 29/109 (26%), Positives = 45/109 (41%), Gaps = 28/109 (25%)

Query: 113 EEGEEEEEEDEEEEKREDGGAGSTEKVE------PEEDRELAPTSRES------------ 154
           E G+ E++E+EE+E +E       EK E      PE+ +  +P   E+            
Sbjct: 695 EVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVK 754

Query: 155 ---PQETNPPGE--SEEAAREAGGGKDGCREDRVENETRPQKRKGQRSE 198
               +ET   G+   +E  +E  GG+ G      E E   +  KG R E
Sbjct: 755 VHLEKETKEEGKPLQQEKEKEKAGGEGGS-----EEEGSDKGAKGSRKE 798


>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
           [Homo sapiens]
          Length = 540

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 28/75 (37%), Positives = 39/75 (52%), Gaps = 5/75 (6%)

Query: 113 EEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAAREAG 172
           EEGE+EEEE +EEE+ ED GA S +  E   ++E +    E  QE     E E  A   G
Sbjct: 147 EEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQE-----EGETEAEAEG 201

Query: 173 GGKDGCREDRVENET 187
              +   E +VE ++
Sbjct: 202 EEAEAKEEKKVEEKS 216



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 28/94 (29%), Positives = 42/94 (44%), Gaps = 5/94 (5%)

Query: 110 EDGEEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAAR 169
           E  EE EEE E +EEE   +     +T     EE+ E      +  +E    G   + A 
Sbjct: 114 EAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAE 173

Query: 170 EAGGGKDGCRE----DRVENETRPQKRKGQRSEA 199
           E G  K+G  E    ++ E ET  +  +G+ +EA
Sbjct: 174 EGGSEKEGSSEKEEGEQEEGETEAE-AEGEEAEA 206



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 25/89 (28%), Positives = 39/89 (43%), Gaps = 6/89 (6%)

Query: 110 EDGEEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAAR 169
           E+ +E  EE+EE+ E E+ E     S  K    E +E      E  ++    G+ EE   
Sbjct: 110 EEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKE------EEGEKEEEEGQEEEEEE 163

Query: 170 EAGGGKDGCREDRVENETRPQKRKGQRSE 198
           + G   D   E   E E   +K +G++ E
Sbjct: 164 DEGAKSDQAEEGGSEKEGSSEKEEGEQEE 192



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 32/98 (32%), Positives = 50/98 (51%), Gaps = 14/98 (14%)

Query: 107 VSLEDGEEGEEEEEEDEEEE-------KREDGGA---GSTEKVEPE-EDRELAPTSRESP 155
           V  E+GE+ EEE +E+EEEE       + E+GG+   GS+EK E E E+ E    +    
Sbjct: 144 VKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEE 203

Query: 156 QETNPPGESEEAAREAGGGKDGCREDRVENETRPQKRK 193
            E     + EE + E    ++   + +VE   +P+K K
Sbjct: 204 AEAKEEKKVEEKSEEVATKEELVADAKVE---KPEKAK 238



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 26/112 (23%), Positives = 51/112 (45%), Gaps = 11/112 (9%)

Query: 110 EDGEEGEEEEEEDEEEEKREDGGA---GSTEKVEPEEDRELAPTSRESPQETNPPGESEE 166
           E  EEG+  ++E E+E+   +GG+   GS +  +     ++A       +E     E E+
Sbjct: 384 ETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKE-----EVEQ 438

Query: 167 AAREAGGGKD---GCREDRVENETRPQKRKGQRSEAAPLHVSCLLLVTDEHG 215
             +E G G++   G   + ++     +K+ G +SE   +    +  +T E G
Sbjct: 439 ETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITSEGG 490



 Score = 30.8 bits (68), Expect = 4.5
 Identities = 29/109 (26%), Positives = 45/109 (41%), Gaps = 28/109 (25%)

Query: 113 EEGEEEEEEDEEEEKREDGGAGSTEKVE------PEEDRELAPTSRES------------ 154
           E G+ E++E+EE+E +E       EK E      PE+ +  +P   E+            
Sbjct: 319 EVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVK 378

Query: 155 ---PQETNPPGE--SEEAAREAGGGKDGCREDRVENETRPQKRKGQRSE 198
               +ET   G+   +E  +E  GG+ G      E E   +  KG R E
Sbjct: 379 VHLEKETKEEGKPLQQEKEKEKAGGEGGS-----EEEGSDKGAKGSRKE 422


>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
            [Homo sapiens]
          Length = 2073

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 44/148 (29%), Positives = 70/148 (47%), Gaps = 22/148 (14%)

Query: 110  EDGEEGEEEEEEDEEEEKREDGGAGSTE------KVEPEEDRELAPTSRESPQETNPPGE 163
            E+ EE EEEEEE+EEEE  E+ G G+ E      K + +E+ E++ T +E     +   E
Sbjct: 1352 EEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEIS-TEKEDSARLDDHEE 1410

Query: 164  SEEAAREAGGGKDGCREDRVENETRPQKRKGQRSEAAPLHVSCLLLVTDEHGTILGI--- 220
             EE   E    +D   +D  E+++  +  + ++ E   L       V +   T L +   
Sbjct: 1411 EEEEDEEPSHNEDHDADD--EDDSHMESAEVEKEE---LPRESFKEVLENQETFLDLNVQ 1465

Query: 221  ------DLLVD-GAQGTASWGSGTKDLA 241
                  ++L+D G   TAS  S  K+LA
Sbjct: 1466 PGHSNPEVLMDCGVDLTASCNSEPKELA 1493



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 24/57 (42%), Positives = 32/57 (56%), Gaps = 4/57 (7%)

Query: 104  ISFVSLEDGEEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNP 160
            +S  S E+ EE E+EEEE+EEEE+ ED      E+ E EE+ E        P+ T P
Sbjct: 1064 LSKESSEEEEEEEDEEEEEEEEEEEED----EEEEEEEEEEEEEENIQSSPPRLTKP 1116



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 20/49 (40%), Positives = 30/49 (61%)

Query: 108  SLEDGEEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQ 156
            S E+ EE +EEEEE+EEEE+ ++      E+ E EE+ + +P     PQ
Sbjct: 1069 SEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQ 1117



 Score = 39.3 bits (90), Expect = 0.013
 Identities = 20/46 (43%), Positives = 25/46 (54%)

Query: 116  EEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPP 161
            EEEEEEDEEEE+ E+      E+ E EE+ E     + SP     P
Sbjct: 1071 EEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKP 1116



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 21/51 (41%), Positives = 27/51 (52%), Gaps = 7/51 (13%)

Query: 109  LEDGEEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETN 159
            LE  +E  EEEEE+E+EE+ E       E+ E EED E      E  +E N
Sbjct: 1062 LELSKESSEEEEEEEDEEEEE-------EEEEEEEDEEEEEEEEEEEEEEN 1105



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 16/49 (32%), Positives = 25/49 (51%)

Query: 113  EEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPP 161
            E  +E  EE+EEEE  E+      E+ + EE+ E      E   +++PP
Sbjct: 1063 ELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPP 1111



 Score = 31.2 bits (69), Expect = 3.4
 Identities = 28/104 (26%), Positives = 41/104 (39%), Gaps = 8/104 (7%)

Query: 101  SPYISFVSLEDGEEGEE--EEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQET 158
            SP    +  E  E GE    +EE+  EE        ++   +PE+D        E  +E 
Sbjct: 1301 SPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEE 1360

Query: 159  NPPGESEEAAREAGGGK-----DGCR-EDRVENETRPQKRKGQR 196
                E EE   E GGG      DG + +++ E E   +K    R
Sbjct: 1361 EEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSAR 1404


>gi|10864057 protamine 3 [Homo sapiens]
          Length = 103

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 34/96 (35%), Positives = 42/96 (43%), Gaps = 11/96 (11%)

Query: 71  LGQGAEPGPGPGLGTAWLLGDNPPLHLRDLSPYISFVSLED------GEEGEEEEEEDEE 124
           L  G  PG  PG  T    G     H   +   ++ VS ++      GEE EEEEEE EE
Sbjct: 8   LNTGQSPGHSPGHSTGHGRG-----HESSMKKLMACVSQDNFSLSSAGEEEEEEEEEGEE 62

Query: 125 EEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNP 160
           EEK E    G    +EPE   E    + E+ Q   P
Sbjct: 63  EEKEELPVQGKLLLLEPERQEEGQKDNAEAQQSPEP 98


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
           sapiens]
          Length = 1152

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 32/100 (32%), Positives = 45/100 (45%), Gaps = 11/100 (11%)

Query: 110 EDGEEGEEEEEEDEEEEKREDGGAGSTEKVEPE-----------EDRELAPTSRESPQET 158
           E+GEEGE E EE+E E + E+ G G  E+ E E           E+ E      E  +E 
Sbjct: 869 EEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEG 928

Query: 159 NPPGESEEAAREAGGGKDGCREDRVENETRPQKRKGQRSE 198
              GE EE   E   G+    E+  E E   ++ +G+  E
Sbjct: 929 EGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEE 968



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 32/105 (30%), Positives = 46/105 (43%), Gaps = 16/105 (15%)

Query: 110 EDGEEGEEEEEEDEEEEKREDGG---------AGSTEKVEPEEDRELAPTSRESPQETNP 160
           E+  EGEEEE + EEEE++E  G          G  EK E E  +E      E  +E   
Sbjct: 733 EEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGD 792

Query: 161 PGESEE-------AAREAGGGKDGCREDRVENETRPQKRKGQRSE 198
            GE EE         +E GG  +G   +  + E   ++ +G+  E
Sbjct: 793 QGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEE 837



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 32/92 (34%), Positives = 40/92 (43%), Gaps = 5/92 (5%)

Query: 111 DGEEGEEEEEEDEEEEKRE----DGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEE 166
           D  EGEEEE E   EEK E    +GG     K E EE+ E      E  +     GE EE
Sbjct: 792 DQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEE 851

Query: 167 AAREAGGGKDGCREDRVENETRPQKRKGQRSE 198
              E  G ++G  E   E E    + +G+  E
Sbjct: 852 EEGEGKGEEEG-EEGEGEEEGEEGEGEGEEEE 882



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 26/85 (30%), Positives = 38/85 (44%)

Query: 111 DGEEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAARE 170
           +GEE E E EE+E E + E+G     E+ E  E  E         +E    GE EE    
Sbjct: 834 EGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEG 893

Query: 171 AGGGKDGCREDRVENETRPQKRKGQ 195
            G  ++G  E   E E   ++ +G+
Sbjct: 894 EGEEEEGEGEGEEEGEGEGEEEEGE 918



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 30/88 (34%), Positives = 42/88 (47%), Gaps = 2/88 (2%)

Query: 113  EEGEEEEEEDEEEEKREDGGAGSTE-KVEPEEDRELAPTSRESPQETNPPGESEEAAREA 171
            EEGE E EE+E EE+ E+ G G  E + E EE+ E         +E    GE EE   E 
Sbjct: 984  EEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEG 1043

Query: 172  -GGGKDGCREDRVENETRPQKRKGQRSE 198
                K+G  E+   N    ++ +G+  E
Sbjct: 1044 EEREKEGEGEENRRNREEEEEEEGKYQE 1071



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 31/93 (33%), Positives = 40/93 (43%), Gaps = 4/93 (4%)

Query: 110 EDGEEGEEEEEEDEEEE----KREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESE 165
           E+  EGEEEE E EEEE      E+G  G  E+   E + E      E   E    GE E
Sbjct: 837 EEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGE 896

Query: 166 EAAREAGGGKDGCREDRVENETRPQKRKGQRSE 198
           E   E  G ++G  E   E      + +G+  E
Sbjct: 897 EEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGE 929



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 30/87 (34%), Positives = 42/87 (48%), Gaps = 2/87 (2%)

Query: 113  EEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAAREAG 172
            EEGE E EE+E E + E+ G G  E+ E E + E      E  +E    GE E    E G
Sbjct: 951  EEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEE-EEGEEEGEEEGEGEEEG 1009

Query: 173  GGK-DGCREDRVENETRPQKRKGQRSE 198
             G+ +   E  VE E   ++ +G+  E
Sbjct: 1010 EGEGEEEEEGEVEGEVEGEEGEGEGEE 1036



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 24/59 (40%), Positives = 33/59 (55%), Gaps = 3/59 (5%)

Query: 111  DGEEGE---EEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEE 166
            +GEEGE   EEEE +EE E+RE  G G   +   EE+ E     +E+ +E N   + EE
Sbjct: 1026 EGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEE 1084



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 33/89 (37%), Positives = 44/89 (49%), Gaps = 5/89 (5%)

Query: 110 EDGE-EGEEEEEEDEEEEKREDG-GAGSTEKVEPEEDRELAPTSRESPQETNPPGESE-E 166
           E+GE +GEEE EE E EE+ E+G G G  E+ E E + E      E   E     E E E
Sbjct: 852 EEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGE 911

Query: 167 AAREAGGGKDGCREDRVENETRPQKRKGQ 195
              E G GK    E+  E E   ++ +G+
Sbjct: 912 GEEEEGEGKG--EEEGEEGEGEGEEEEGE 938



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 32/91 (35%), Positives = 42/91 (46%), Gaps = 7/91 (7%)

Query: 110 EDGEEGEEEE--EEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEA 167
           E+GEEGE EE  EE E E + E+G     E+ E E + E      E   E    GE EE 
Sbjct: 860 EEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEE----EGEGEGEEEGEGEGEEE 915

Query: 168 AREAGGGKDGCREDRVENETRPQKRKGQRSE 198
             E  G ++G  E   E E    + +G+  E
Sbjct: 916 EGEGKGEEEG-EEGEGEGEEEEGEGEGEDGE 945



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 29/81 (35%), Positives = 37/81 (45%), Gaps = 1/81 (1%)

Query: 111  DGEEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAARE 170
            +GEE E EEE +EE E  E+G     E+ E E + E+     E   E    GE E   RE
Sbjct: 989  EGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGE-EEEGEEEGEERE 1047

Query: 171  AGGGKDGCREDRVENETRPQK 191
              G  +  R +R E E    K
Sbjct: 1048 KEGEGEENRRNREEEEEEEGK 1068



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 30/94 (31%), Positives = 42/94 (44%), Gaps = 10/94 (10%)

Query: 111  DGEEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAAR- 169
            +GEE  E E E+ E E  E+ G G  E+ E EE+ E      E  +E    GE EE    
Sbjct: 965  EGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGE---EEGEGEEEGEGEGEEEEEGEV 1021

Query: 170  ------EAGGGKDGCREDRVENETRPQKRKGQRS 197
                  E G G+    E   E E R ++ +G+ +
Sbjct: 1022 EGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEEN 1055



 Score = 38.5 bits (88), Expect = 0.021
 Identities = 29/97 (29%), Positives = 45/97 (46%), Gaps = 6/97 (6%)

Query: 109 LEDGEEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAA 168
           +E   EGE+E  E +EE K+ DG     ++ E    +E      E  +E +  GE EE  
Sbjct: 686 MERPGEGEKELAE-KEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGD 744

Query: 169 RE-----AGGGKDGCREDRVENETRPQKRKGQRSEAA 200
           RE      G GK+    + VE E   ++ + ++ E A
Sbjct: 745 REEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERA 781



 Score = 37.4 bits (85), Expect = 0.048
 Identities = 28/90 (31%), Positives = 42/90 (46%), Gaps = 10/90 (11%)

Query: 109 LEDGEEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAA 168
           +E+G+   EEEEE+ E E+ E  G G  E+ E EE+           +E    GE EE  
Sbjct: 819 VEEGKGEREEEEEEGEGEEEE--GEGEEEEGEGEEEE-----GEGKGEEEGEEGEGEEEG 871

Query: 169 REA---GGGKDGCREDRVENETRPQKRKGQ 195
            E    G  ++G  E   E E   ++ +G+
Sbjct: 872 EEGEGEGEEEEGEGEGEEEGEGEGEEEEGE 901



 Score = 37.0 bits (84), Expect = 0.063
 Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 16/104 (15%)

Query: 111 DGEEGEEEEEEDEEEEKR---------EDGGAGSTEKVEPEEDRELAPTSRESPQETNPP 161
           DGEE E++E E   +++R         E+ G G  E+ + EE+ E     +E  +     
Sbjct: 706 DGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVE 765

Query: 162 GESE----EAAREAGGGKDGCRE---DRVENETRPQKRKGQRSE 198
           GE E    E  +E   GK+   E   D+ E E    + +G+  E
Sbjct: 766 GEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKE 809



 Score = 37.0 bits (84), Expect = 0.063
 Identities = 31/94 (32%), Positives = 46/94 (48%), Gaps = 16/94 (17%)

Query: 110 EDGE----EGEEEEEE-DEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGES 164
           E+GE    EGE E+EE + ++E+R    AG  EK E E D+          +ET   GE 
Sbjct: 757 EEGEGEEVEGEREKEEGERKKEER----AGKEEKGEEEGDQ-----GEGEEEETEGRGEE 807

Query: 165 EEAAREAGGGKDGCREDRVENETRPQKRKGQRSE 198
           +E   E  GG+    E + E E   ++ +G+  E
Sbjct: 808 KEEGGEVEGGE--VEEGKGEREEEEEEGEGEEEE 839



 Score = 37.0 bits (84), Expect = 0.063
 Identities = 28/90 (31%), Positives = 39/90 (43%), Gaps = 1/90 (1%)

Query: 110 EDGEEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAAR 169
           E  EEGE E EE+E E K E+ G     + E EE            +E     E EE   
Sbjct: 903 EGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEG 962

Query: 170 EAGGGKDGCRE-DRVENETRPQKRKGQRSE 198
           E  G ++G  E +  E E   ++ +G+  E
Sbjct: 963 EGEGEEEGEGEGEEGEGEGEEEEGEGEGEE 992



 Score = 37.0 bits (84), Expect = 0.063
 Identities = 26/86 (30%), Positives = 35/86 (40%)

Query: 110  EDGEEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAAR 169
            E+GE   EEE E+ E E  E+ G G  E  E E + E      E  +      E  E   
Sbjct: 915  EEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEG 974

Query: 170  EAGGGKDGCREDRVENETRPQKRKGQ 195
            E G G+    E   E E    + +G+
Sbjct: 975  EEGEGEGEEEEGEGEGEEEEGEEEGE 1000



 Score = 37.0 bits (84), Expect = 0.063
 Identities = 27/78 (34%), Positives = 34/78 (43%), Gaps = 1/78 (1%)

Query: 110  EDGE-EGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAA 168
            E+GE EGE+ E E EEEE   +G     E    EE            +E    GE EE  
Sbjct: 935  EEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEE 994

Query: 169  REAGGGKDGCREDRVENE 186
             E  G ++G  E+  E E
Sbjct: 995  GEEEGEEEGEGEEEGEGE 1012



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 31/94 (32%), Positives = 41/94 (43%), Gaps = 7/94 (7%)

Query: 110 EDGEEGEEE-----EEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGES 164
           E+GE  EEE     EEE EE E  E+G  G  E  E E + E         +E    GE 
Sbjct: 845 EEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEG 904

Query: 165 EEAAREAGGGKDGCREDRVENETRPQKRKGQRSE 198
           EE     G  ++G  E + E E    + +G+  E
Sbjct: 905 EEEGEGEGEEEEG--EGKGEEEGEEGEGEGEEEE 936



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 26/86 (30%), Positives = 36/86 (41%)

Query: 113 EEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAAREAG 172
           EEGE E EE+ E E  E+ G G  E+   E + E      E   E       EE     G
Sbjct: 898 EEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEG 957

Query: 173 GGKDGCREDRVENETRPQKRKGQRSE 198
             ++G  E   E E   ++ +G+  E
Sbjct: 958 EEEEGEGEGEEEGEGEGEEGEGEGEE 983



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 24/72 (33%), Positives = 31/72 (43%)

Query: 110  EDGEEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAAR 169
            E+  EGE EEEE+ E E   +G  G  E  E E + E     +E   E N     EE   
Sbjct: 1006 EEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEE 1065

Query: 170  EAGGGKDGCRED 181
            E    + G  E+
Sbjct: 1066 EGKYQETGEEEN 1077



 Score = 35.4 bits (80), Expect = 0.18
 Identities = 25/89 (28%), Positives = 38/89 (42%), Gaps = 20/89 (22%)

Query: 110 EDGEEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAAR 169
           E+G  G E  +++E E+  +D G G  E+                P E    GE E A +
Sbjct: 660 EEGSSGAEHWQDEEREKGEKDKGRGEMER----------------PGE----GEKELAEK 699

Query: 170 EAGGGKDGCREDRVENETRPQKRKGQRSE 198
           E    +DG  +++ E E   QK + Q  E
Sbjct: 700 EEWKKRDGEEQEQKEREQGHQKERNQEME 728



 Score = 33.9 bits (76), Expect = 0.53
 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 1/75 (1%)

Query: 111  DGEEGEEEEEEDEEEEKREDG-GAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAAR 169
            +GE  EEEE E E E + E+G G G  E+ E E +        E  +      E EE   
Sbjct: 1010 EGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKY 1069

Query: 170  EAGGGKDGCREDRVE 184
            +  G ++  R+D  E
Sbjct: 1070 QETGEEENERQDGEE 1084



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 26/92 (28%), Positives = 40/92 (43%), Gaps = 5/92 (5%)

Query: 110 EDGEEGEEE---EEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEE 166
           E+GE  +EE   +EE  EEE   D G G  E+ E   + +      E  +     GE EE
Sbjct: 771 EEGERKKEERAGKEEKGEEE--GDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREE 828

Query: 167 AAREAGGGKDGCREDRVENETRPQKRKGQRSE 198
              E  G ++    +  E E   ++ +G+  E
Sbjct: 829 EEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEE 860



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 32/91 (35%), Positives = 44/91 (48%), Gaps = 5/91 (5%)

Query: 110 EDGEEG-EEEEEEDEEEEKREDG-GAGSTEKVEPE-EDRELAPTSRESPQE-TNPPGESE 165
           E+GE   EEEE E + EE+ E+G G G  E+ E E ED E      E   E     GE E
Sbjct: 906 EEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGE 965

Query: 166 EAAREAGGGKDGCRE-DRVENETRPQKRKGQ 195
                 G G++G  E +  E E   ++ +G+
Sbjct: 966 GEEEGEGEGEEGEGEGEEEEGEGEGEEEEGE 996



 Score = 32.0 bits (71), Expect = 2.0
 Identities = 20/77 (25%), Positives = 35/77 (45%), Gaps = 10/77 (12%)

Query: 110  EDGEEGEEE----------EEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETN 159
            E+GEE E+E          EEE+EEE K ++ G    E+ + EE ++++          +
Sbjct: 1041 EEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGSVKYGKH 1100

Query: 160  PPGESEEAAREAGGGKD 176
               + +      G GK+
Sbjct: 1101 KTYQKKSVTNTQGNGKE 1117


>gi|42476169 Paf1, RNA polymerase II associated factor, homolog
           [Homo sapiens]
          Length = 531

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 21/71 (29%), Positives = 38/71 (53%)

Query: 111 DGEEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAARE 170
           +  E EEEEEE+ E E++E GG+   ++     ++E +       +     G+ +EA+ +
Sbjct: 372 ENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDK 431

Query: 171 AGGGKDGCRED 181
           +G G+D   ED
Sbjct: 432 SGSGEDESSED 442



 Score = 32.0 bits (71), Expect = 2.0
 Identities = 19/84 (22%), Positives = 39/84 (46%), Gaps = 6/84 (7%)

Query: 117 EEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAAREAGGGKD 176
           +  + +E+E + ++      E  EPEE+ E         +E    G  EE  + +   K+
Sbjct: 352 KHRDMNEKELEAQEARKAQLENHEPEEEEE----EEMETEEKEAGGSDEEQEKGSSSEKE 407

Query: 177 GCREDRVENETRPQKRKGQRSEAA 200
           G  ++   +E+  ++ +G R EA+
Sbjct: 408 GSEDEHSGSES--EREEGDRDEAS 429



 Score = 30.8 bits (68), Expect = 4.5
 Identities = 26/91 (28%), Positives = 43/91 (47%), Gaps = 4/91 (4%)

Query: 112 GEEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAA-RE 170
           G + E+E+    E+E  ED  +GS E    E DR+ A     S ++ +   E+  A  +E
Sbjct: 393 GSDEEQEKGSSSEKEGSEDEHSGS-ESEREEGDRDEASDKSGSGEDESSEDEARAARDKE 451

Query: 171 AGGGKDGCREDRV--ENETRPQKRKGQRSEA 199
              G D   ED    ++E R Q + G  +++
Sbjct: 452 EIFGSDADSEDDADSDDEDRGQAQGGSDNDS 482


>gi|4503257 death-domain associated protein isoform a [Homo sapiens]
          Length = 740

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 11/88 (12%)

Query: 90  GDNPPLHLRDLSPYISFVSLEDGEEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAP 149
           G+ P        P  S    +D ++ E +EEE+EEEE+ E+      E  + EE+ +L  
Sbjct: 416 GEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEE------EATDSEEEEDL-- 467

Query: 150 TSRESPQETNPPGESEEAAREAGGGKDG 177
              E  QE     E E+   EA  GKDG
Sbjct: 468 ---EQMQEGQEDDEEEDEEEEAAAGKDG 492



 Score = 34.3 bits (77), Expect = 0.41
 Identities = 16/54 (29%), Positives = 30/54 (55%), Gaps = 3/54 (5%)

Query: 109 LEDGEEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAP---TSRESPQETN 159
           +++G+E +EEE+E+EE    +DG       ++   ++ L P    SR S ++ N
Sbjct: 470 MQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQN 523



 Score = 33.1 bits (74), Expect = 0.90
 Identities = 18/62 (29%), Positives = 30/62 (48%), Gaps = 2/62 (3%)

Query: 110 EDGEEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESP--QETNPPGESEEA 167
           ED E+ +E +E+DEEE++ E+  AG      P    +++      P  Q +   GE +  
Sbjct: 465 EDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNK 524

Query: 168 AR 169
            R
Sbjct: 525 GR 526


>gi|215422388 death-domain associated protein isoform a [Homo
           sapiens]
          Length = 740

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 11/88 (12%)

Query: 90  GDNPPLHLRDLSPYISFVSLEDGEEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAP 149
           G+ P        P  S    +D ++ E +EEE+EEEE+ E+      E  + EE+ +L  
Sbjct: 416 GEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEE------EATDSEEEEDL-- 467

Query: 150 TSRESPQETNPPGESEEAAREAGGGKDG 177
              E  QE     E E+   EA  GKDG
Sbjct: 468 ---EQMQEGQEDDEEEDEEEEAAAGKDG 492



 Score = 34.3 bits (77), Expect = 0.41
 Identities = 16/54 (29%), Positives = 30/54 (55%), Gaps = 3/54 (5%)

Query: 109 LEDGEEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAP---TSRESPQETN 159
           +++G+E +EEE+E+EE    +DG       ++   ++ L P    SR S ++ N
Sbjct: 470 MQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQN 523



 Score = 33.1 bits (74), Expect = 0.90
 Identities = 18/62 (29%), Positives = 30/62 (48%), Gaps = 2/62 (3%)

Query: 110 EDGEEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESP--QETNPPGESEEA 167
           ED E+ +E +E+DEEE++ E+  AG      P    +++      P  Q +   GE +  
Sbjct: 465 EDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNK 524

Query: 168 AR 169
            R
Sbjct: 525 GR 526


>gi|215422366 death-domain associated protein isoform b [Homo
           sapiens]
          Length = 752

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 11/88 (12%)

Query: 90  GDNPPLHLRDLSPYISFVSLEDGEEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAP 149
           G+ P        P  S    +D ++ E +EEE+EEEE+ E+      E  + EE+ +L  
Sbjct: 428 GEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEE------EATDSEEEEDL-- 479

Query: 150 TSRESPQETNPPGESEEAAREAGGGKDG 177
              E  QE     E E+   EA  GKDG
Sbjct: 480 ---EQMQEGQEDDEEEDEEEEAAAGKDG 504



 Score = 34.3 bits (77), Expect = 0.41
 Identities = 16/54 (29%), Positives = 30/54 (55%), Gaps = 3/54 (5%)

Query: 109 LEDGEEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAP---TSRESPQETN 159
           +++G+E +EEE+E+EE    +DG       ++   ++ L P    SR S ++ N
Sbjct: 482 MQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQN 535



 Score = 33.1 bits (74), Expect = 0.90
 Identities = 18/62 (29%), Positives = 30/62 (48%), Gaps = 2/62 (3%)

Query: 110 EDGEEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESP--QETNPPGESEEA 167
           ED E+ +E +E+DEEE++ E+  AG      P    +++      P  Q +   GE +  
Sbjct: 477 EDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNK 536

Query: 168 AR 169
            R
Sbjct: 537 GR 538


>gi|218505694 potassium channel tetramerisation domain containing 1
           isoform b [Homo sapiens]
          Length = 865

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 27/63 (42%), Positives = 33/63 (52%), Gaps = 8/63 (12%)

Query: 112 GEEGEEEEEEDE--------EEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGE 163
           GEE EEEEEEDE        +EE+ EDGG G  E  E EE+ E+     E  +  +  GE
Sbjct: 54  GEEEEEEEEEDEIQEVQITGDEEEEEDGGGGLEEDEEEEEEEEMGLDWDEPLEPEDSAGE 113

Query: 164 SEE 166
             E
Sbjct: 114 ELE 116



 Score = 35.4 bits (80), Expect = 0.18
 Identities = 27/78 (34%), Positives = 35/78 (44%), Gaps = 12/78 (15%)

Query: 112 GEEGEEEE-----EEDEEEEKREDGGAGSTEKVEPEED--RELAP-----TSRESPQETN 159
           G+E EEE+     EEDEEEE+ E+ G    E +EPE+    EL P      + +      
Sbjct: 73  GDEEEEEDGGGGLEEDEEEEEEEEMGLDWDEPLEPEDSAGEELEPEPVHMINMDQSAALE 132

Query: 160 PPGESEEAAREAGGGKDG 177
           P       A  A GG  G
Sbjct: 133 PEAPPRLLAPRARGGPPG 150


>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
          Length = 770

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 42/139 (30%), Positives = 59/139 (42%), Gaps = 19/139 (13%)

Query: 71  LGQGAEPGPGPGLGTAWLLGDNPPLHLRDLSPY---ISFVSLEDGEEGEEEEEEDEEEEK 127
           LG G +P     +    LL D     L+D+S      S       E G   EEE+EEEE+
Sbjct: 233 LGDGRKPVKEEKMEERDLLSD-----LQDISDSERKTSSAESSSAESGSGSEEEEEEEEE 287

Query: 128 REDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAAREAGGGKDGCREDR----- 182
            E+ G+ S E  E EE+ E      E    +N    SE++A E    +    E+R     
Sbjct: 288 EEEEGSTSEESEEEEEEEE----EEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENH 343

Query: 183 --VENETRPQKRKGQRSEA 199
             V  E+R  +  G+  EA
Sbjct: 344 LLVVPESRFDRDSGESEEA 362



 Score = 37.7 bits (86), Expect = 0.037
 Identities = 28/83 (33%), Positives = 34/83 (40%), Gaps = 18/83 (21%)

Query: 110 EDGEEGE--EEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQE---------- 157
           E+ EEG   EE EE+EEEE+ E+   GS  +   E+  E       S  E          
Sbjct: 287 EEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLV 346

Query: 158 ------TNPPGESEEAAREAGGG 174
                     GESEEA  E G G
Sbjct: 347 VPESRFDRDSGESEEAEEEVGEG 369


>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
          Length = 780

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 42/139 (30%), Positives = 59/139 (42%), Gaps = 19/139 (13%)

Query: 71  LGQGAEPGPGPGLGTAWLLGDNPPLHLRDLSPY---ISFVSLEDGEEGEEEEEEDEEEEK 127
           LG G +P     +    LL D     L+D+S      S       E G   EEE+EEEE+
Sbjct: 243 LGDGRKPVKEEKMEERDLLSD-----LQDISDSERKTSSAESSSAESGSGSEEEEEEEEE 297

Query: 128 REDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAAREAGGGKDGCREDR----- 182
            E+ G+ S E  E EE+ E      E    +N    SE++A E    +    E+R     
Sbjct: 298 EEEEGSTSEESEEEEEEEE----EEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENH 353

Query: 183 --VENETRPQKRKGQRSEA 199
             V  E+R  +  G+  EA
Sbjct: 354 LLVVPESRFDRDSGESEEA 372



 Score = 37.7 bits (86), Expect = 0.037
 Identities = 28/83 (33%), Positives = 34/83 (40%), Gaps = 18/83 (21%)

Query: 110 EDGEEGE--EEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQE---------- 157
           E+ EEG   EE EE+EEEE+ E+   GS  +   E+  E       S  E          
Sbjct: 297 EEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLV 356

Query: 158 ------TNPPGESEEAAREAGGG 174
                     GESEEA  E G G
Sbjct: 357 VPESRFDRDSGESEEAEEEVGEG 379


>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           9 [Homo sapiens]
          Length = 771

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 42/139 (30%), Positives = 59/139 (42%), Gaps = 19/139 (13%)

Query: 71  LGQGAEPGPGPGLGTAWLLGDNPPLHLRDLSPY---ISFVSLEDGEEGEEEEEEDEEEEK 127
           LG G +P     +    LL D     L+D+S      S       E G   EEE+EEEE+
Sbjct: 234 LGDGRKPVKEEKMEERDLLSD-----LQDISDSERKTSSAESSSAESGSGSEEEEEEEEE 288

Query: 128 REDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAAREAGGGKDGCREDR----- 182
            E+ G+ S E  E EE+ E      E    +N    SE++A E    +    E+R     
Sbjct: 289 EEEEGSTSEESEEEEEEEE----EEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENH 344

Query: 183 --VENETRPQKRKGQRSEA 199
             V  E+R  +  G+  EA
Sbjct: 345 LLVVPESRFDRDSGESEEA 363



 Score = 37.7 bits (86), Expect = 0.037
 Identities = 28/83 (33%), Positives = 34/83 (40%), Gaps = 18/83 (21%)

Query: 110 EDGEEGE--EEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQE---------- 157
           E+ EEG   EE EE+EEEE+ E+   GS  +   E+  E       S  E          
Sbjct: 288 EEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLV 347

Query: 158 ------TNPPGESEEAAREAGGG 174
                     GESEEA  E G G
Sbjct: 348 VPESRFDRDSGESEEAEEEVGEG 370


>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           8 [Homo sapiens]
          Length = 780

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 42/139 (30%), Positives = 59/139 (42%), Gaps = 19/139 (13%)

Query: 71  LGQGAEPGPGPGLGTAWLLGDNPPLHLRDLSPY---ISFVSLEDGEEGEEEEEEDEEEEK 127
           LG G +P     +    LL D     L+D+S      S       E G   EEE+EEEE+
Sbjct: 243 LGDGRKPVKEEKMEERDLLSD-----LQDISDSERKTSSAESSSAESGSGSEEEEEEEEE 297

Query: 128 REDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAAREAGGGKDGCREDR----- 182
            E+ G+ S E  E EE+ E      E    +N    SE++A E    +    E+R     
Sbjct: 298 EEEEGSTSEESEEEEEEEE----EEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENH 353

Query: 183 --VENETRPQKRKGQRSEA 199
             V  E+R  +  G+  EA
Sbjct: 354 LLVVPESRFDRDSGESEEA 372



 Score = 37.7 bits (86), Expect = 0.037
 Identities = 28/83 (33%), Positives = 34/83 (40%), Gaps = 18/83 (21%)

Query: 110 EDGEEGE--EEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQE---------- 157
           E+ EEG   EE EE+EEEE+ E+   GS  +   E+  E       S  E          
Sbjct: 297 EEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLV 356

Query: 158 ------TNPPGESEEAAREAGGG 174
                     GESEEA  E G G
Sbjct: 357 VPESRFDRDSGESEEAEEEVGEG 379


>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           5 [Homo sapiens]
          Length = 748

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 42/139 (30%), Positives = 59/139 (42%), Gaps = 19/139 (13%)

Query: 71  LGQGAEPGPGPGLGTAWLLGDNPPLHLRDLSPY---ISFVSLEDGEEGEEEEEEDEEEEK 127
           LG G +P     +    LL D     L+D+S      S       E G   EEE+EEEE+
Sbjct: 211 LGDGRKPVKEEKMEERDLLSD-----LQDISDSERKTSSAESSSAESGSGSEEEEEEEEE 265

Query: 128 REDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAAREAGGGKDGCREDR----- 182
            E+ G+ S E  E EE+ E      E    +N    SE++A E    +    E+R     
Sbjct: 266 EEEEGSTSEESEEEEEEEE----EEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENH 321

Query: 183 --VENETRPQKRKGQRSEA 199
             V  E+R  +  G+  EA
Sbjct: 322 LLVVPESRFDRDSGESEEA 340



 Score = 37.7 bits (86), Expect = 0.037
 Identities = 28/83 (33%), Positives = 34/83 (40%), Gaps = 18/83 (21%)

Query: 110 EDGEEGE--EEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQE---------- 157
           E+ EEG   EE EE+EEEE+ E+   GS  +   E+  E       S  E          
Sbjct: 265 EEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLV 324

Query: 158 ------TNPPGESEEAAREAGGG 174
                     GESEEA  E G G
Sbjct: 325 VPESRFDRDSGESEEAEEEVGEG 347


>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           4 [Homo sapiens]
          Length = 737

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 42/139 (30%), Positives = 59/139 (42%), Gaps = 19/139 (13%)

Query: 71  LGQGAEPGPGPGLGTAWLLGDNPPLHLRDLSPY---ISFVSLEDGEEGEEEEEEDEEEEK 127
           LG G +P     +    LL D     L+D+S      S       E G   EEE+EEEE+
Sbjct: 200 LGDGRKPVKEEKMEERDLLSD-----LQDISDSERKTSSAESSSAESGSGSEEEEEEEEE 254

Query: 128 REDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAAREAGGGKDGCREDR----- 182
            E+ G+ S E  E EE+ E      E    +N    SE++A E    +    E+R     
Sbjct: 255 EEEEGSTSEESEEEEEEEE----EEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENH 310

Query: 183 --VENETRPQKRKGQRSEA 199
             V  E+R  +  G+  EA
Sbjct: 311 LLVVPESRFDRDSGESEEA 329



 Score = 37.7 bits (86), Expect = 0.037
 Identities = 28/83 (33%), Positives = 34/83 (40%), Gaps = 18/83 (21%)

Query: 110 EDGEEGE--EEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQE---------- 157
           E+ EEG   EE EE+EEEE+ E+   GS  +   E+  E       S  E          
Sbjct: 254 EEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLV 313

Query: 158 ------TNPPGESEEAAREAGGG 174
                     GESEEA  E G G
Sbjct: 314 VPESRFDRDSGESEEAEEEVGEG 336


>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           2 [Homo sapiens]
          Length = 782

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 42/139 (30%), Positives = 59/139 (42%), Gaps = 19/139 (13%)

Query: 71  LGQGAEPGPGPGLGTAWLLGDNPPLHLRDLSPY---ISFVSLEDGEEGEEEEEEDEEEEK 127
           LG G +P     +    LL D     L+D+S      S       E G   EEE+EEEE+
Sbjct: 245 LGDGRKPVKEEKMEERDLLSD-----LQDISDSERKTSSAESSSAESGSGSEEEEEEEEE 299

Query: 128 REDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAAREAGGGKDGCREDR----- 182
            E+ G+ S E  E EE+ E      E    +N    SE++A E    +    E+R     
Sbjct: 300 EEEEGSTSEESEEEEEEEE----EEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENH 355

Query: 183 --VENETRPQKRKGQRSEA 199
             V  E+R  +  G+  EA
Sbjct: 356 LLVVPESRFDRDSGESEEA 374



 Score = 37.7 bits (86), Expect = 0.037
 Identities = 28/83 (33%), Positives = 34/83 (40%), Gaps = 18/83 (21%)

Query: 110 EDGEEGE--EEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQE---------- 157
           E+ EEG   EE EE+EEEE+ E+   GS  +   E+  E       S  E          
Sbjct: 299 EEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLV 358

Query: 158 ------TNPPGESEEAAREAGGG 174
                     GESEEA  E G G
Sbjct: 359 VPESRFDRDSGESEEAEEEVGEG 381


>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
          Length = 282

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 28/92 (30%), Positives = 45/92 (48%), Gaps = 4/92 (4%)

Query: 109 LEDGEEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAA 168
           +++ EE ++E+EED+ EEK E G     EK   EED +      E  ++     + ++  
Sbjct: 123 VKNEEEDQKEDEEDQNEEKGEAGKEDKDEK--GEEDGKEDKNGNEKGEDAKEKEDGKKGE 180

Query: 169 REAGGGKDGCR--EDRVENETRPQKRKGQRSE 198
              G G+DG    ED  E E R +   G+ +E
Sbjct: 181 DGKGNGEDGKEKGEDEKEEEDRKETGDGKENE 212



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 27/95 (28%), Positives = 44/95 (46%), Gaps = 5/95 (5%)

Query: 110 EDGEEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSR-ESPQETNPPGESEEAA 168
           EDG+E +   E+ E+ +++EDG  G   K   E+ +E     + E  ++    G+  E  
Sbjct: 155 EDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDG 214

Query: 169 REAGGGKDG----CREDRVENETRPQKRKGQRSEA 199
           +E G  K+G     +ED  E E   +   G   EA
Sbjct: 215 KEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEA 249



 Score = 36.6 bits (83), Expect = 0.082
 Identities = 24/79 (30%), Positives = 41/79 (51%), Gaps = 7/79 (8%)

Query: 110 EDGEEGEEEEEEDEEEEKREDG--GAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEA 167
           EDG+E  E+E+E+E+ ++  DG       EK + +E +++     E  +E    G+ +E 
Sbjct: 187 EDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKERE---DGKEDEG 243

Query: 168 AREAGGGKDGCREDRVENE 186
             E   GK+  +ED  E E
Sbjct: 244 GNEEEAGKE--KEDLKEEE 260



 Score = 32.0 bits (71), Expect = 2.0
 Identities = 15/57 (26%), Positives = 30/57 (52%)

Query: 110 EDGEEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEE 166
           ++G++ + +E+E E E+ +ED G    E  + +ED +     +E  +     G+ EE
Sbjct: 221 KEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEE 277


>gi|21735569 claspin [Homo sapiens]
          Length = 1339

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 26/58 (44%), Positives = 29/58 (50%), Gaps = 4/58 (6%)

Query: 110 EDGEEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEA 167
           EDG E EEEEEE+  +E  EDG     EKVE EE  E      E  +E    G  E A
Sbjct: 625 EDGFEEEEEEEEEMTDESEEDG----EEKVEKEEKEEELEEEEEKEEEEEEEGNQETA 678



 Score = 34.3 bits (77), Expect = 0.41
 Identities = 21/64 (32%), Positives = 35/64 (54%), Gaps = 14/64 (21%)

Query: 108 SLEDGEEGEE--------EEEEDEEEEKREDGGAG------STEKVEPEEDRELAPTSRE 153
           S EDGEE  E        EEEE++EEE+ E+G         S+E++E ++++E+   + +
Sbjct: 642 SEEDGEEKVEKEEKEEELEEEEEKEEEEEEEGNQETAEFLLSSEEIETKDEKEMDKENND 701

Query: 154 SPQE 157
              E
Sbjct: 702 GSSE 705


>gi|148727368 bromodomain and PHD finger containing, 3 [Homo
           sapiens]
          Length = 1205

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 29/78 (37%), Positives = 41/78 (52%), Gaps = 5/78 (6%)

Query: 81  PGLGTAWLLGDNPPLHLRDLSPYISFVSLEDGEEGEEEEEEDEEEEKREDGG-AGSTEKV 139
           PG  TA   GD+P    R +S       L++G+  EEEEEE EEEE+   GG +GS + V
Sbjct: 389 PGAATARRKGDSP----RSISETGDEEGLKEGDGEEEEEEEVEEEEQEAQGGVSGSLKGV 444

Query: 140 EPEEDRELAPTSRESPQE 157
             +    L    ++ P+E
Sbjct: 445 PKKSKMSLKQKIKKEPEE 462


>gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member A [Homo sapiens]
          Length = 249

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 28/88 (31%), Positives = 46/88 (52%), Gaps = 11/88 (12%)

Query: 114 EGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAAREAGG 173
           EG ++EEEDE+EE+ ++      + VE EED +      E  +E +  GE EE   +  G
Sbjct: 165 EGLDDEEEDEDEEEYDE----DAQVVEDEEDED----EEEEGEEEDVSGEEEE---DEEG 213

Query: 174 GKDGCREDRVENETRPQKRKGQRSEAAP 201
             DG  +D  + E   ++ +GQ+ +  P
Sbjct: 214 YNDGEVDDEEDEEELGEEERGQKRKREP 241



 Score = 38.1 bits (87), Expect = 0.028
 Identities = 22/67 (32%), Positives = 33/67 (49%), Gaps = 10/67 (14%)

Query: 110 EDGEEGEEEEEEDEEEEKREDGGAGSTEKVE----------PEEDRELAPTSRESPQETN 159
           ED +  E+EE+EDEEEE  E+  +G  E+ E           E++ EL    R   ++  
Sbjct: 181 EDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKRE 240

Query: 160 PPGESEE 166
           P  E E+
Sbjct: 241 PEDEGED 247


>gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens]
          Length = 543

 Score = 43.1 bits (100), Expect = 9e-04
 Identities = 35/100 (35%), Positives = 43/100 (43%), Gaps = 2/100 (2%)

Query: 101 SPYISFVSLEDGEEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNP 160
           S Y S V  E  E  E  E    EE K E    G  E  E E+D+E A     + +E   
Sbjct: 441 SYYTSHVQEEQIEVEETIEAAKAEEAKDEPPSEGEAE--EEEKDKEEAEEEEAAEEEEAA 498

Query: 161 PGESEEAAREAGGGKDGCREDRVENETRPQKRKGQRSEAA 200
             ESEEA  E  GG+    E+  E E   +K +G   E A
Sbjct: 499 KEESEEAKEEEEGGEGEEGEETKEAEEEEKKVEGAGEEQA 538



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 23/73 (31%), Positives = 36/73 (49%), Gaps = 4/73 (5%)

Query: 111 DGEEGEEEEEED--EEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAA 168
           +GE  EEE++++  EEEE  E+  A   E  E +E+ E      E  +ET    E E+  
Sbjct: 473 EGEAEEEEKDKEEAEEEEAAEEEEAAKEESEEAKEEEE--GGEGEEGEETKEAEEEEKKV 530

Query: 169 REAGGGKDGCRED 181
             AG  +   ++D
Sbjct: 531 EGAGEEQAAKKKD 543



 Score = 30.0 bits (66), Expect = 7.6
 Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 4/71 (5%)

Query: 110 EDGEEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAAR 169
           E  EE +++EE +EEE   E+  A    K E EE +E          E     E EE   
Sbjct: 475 EAEEEEKDKEEAEEEEAAEEEEAA----KEESEEAKEEEEGGEGEEGEETKEAEEEEKKV 530

Query: 170 EAGGGKDGCRE 180
           E  G +   ++
Sbjct: 531 EGAGEEQAAKK 541


>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           3 [Homo sapiens]
          Length = 526

 Score = 43.1 bits (100), Expect = 9e-04
 Identities = 33/96 (34%), Positives = 47/96 (48%), Gaps = 8/96 (8%)

Query: 108 SLEDGEEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEA 167
           S E G  G EEEEE+EEEE+ E   +  +E+ E EE+ E   T   S + +    +S E 
Sbjct: 27  SAESGS-GSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASE---QSAEE 82

Query: 168 AREAGGGKDGCREDR----VENETRPQKRKGQRSEA 199
             E    +D  RE+     V  E+R  +  G+  EA
Sbjct: 83  VSEEEMSEDEERENENHLLVVPESRFDRDSGESEEA 118



 Score = 37.7 bits (86), Expect = 0.037
 Identities = 28/83 (33%), Positives = 34/83 (40%), Gaps = 18/83 (21%)

Query: 110 EDGEEGE--EEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQE---------- 157
           E+ EEG   EE EE+EEEE+ E+   GS  +   E+  E       S  E          
Sbjct: 43  EEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLV 102

Query: 158 ------TNPPGESEEAAREAGGG 174
                     GESEEA  E G G
Sbjct: 103 VPESRFDRDSGESEEAEEEVGEG 125



 Score = 37.0 bits (84), Expect = 0.063
 Identities = 22/82 (26%), Positives = 31/82 (37%), Gaps = 3/82 (3%)

Query: 117 EEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEAAREAGGGKD 176
           E +    E    E G     E+ E EE+ E   TS ES +E     E EE   E G   +
Sbjct: 17  ERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEE---EEEEEEEETGSNSE 73

Query: 177 GCREDRVENETRPQKRKGQRSE 198
              E   E  +  +  + +  E
Sbjct: 74  EASEQSAEEVSEEEMSEDEERE 95



 Score = 34.7 bits (78), Expect = 0.31
 Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 8/81 (9%)

Query: 108 SLEDGEEGEEEEEEDEEEEKREDGGAGSTEKVEPEEDRELAPTSRESPQETNPPGESEEA 167
           S E          E+EEEE+ E+   GST +   EE+ E      E  +E      SEEA
Sbjct: 22  SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE------EEEEEEETGSNSEEA 75

Query: 168 AREAGGGKDGCREDRVENETR 188
           + ++   ++   E+  E+E R
Sbjct: 76  SEQS--AEEVSEEEMSEDEER 94


>gi|4758392 forkhead box D1 [Homo sapiens]
          Length = 465

 Score = 43.1 bits (100), Expect = 9e-04
 Identities = 32/87 (36%), Positives = 39/87 (44%), Gaps = 27/87 (31%)

Query: 115 GEEEEEEDEEEEKREDGGAG---------------------STEKVEPEEDRE---LAPT 150
           GE E+EEDEEEE  ++GG G                       E +E EED +   LAP 
Sbjct: 23  GEGEDEEDEEEEDDDEGGGGGPRLAVPAQRRRRRRSYAGEDELEDLEEEEDDDDILLAPP 82

Query: 151 SRESPQETNPPGESEEAAREAGGGKDG 177
           +  SP    PPG +  A   AGGG  G
Sbjct: 83  AGGSPA---PPGPAPAAGAGAGGGGGG 106


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.137    0.431 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,115,604
Number of Sequences: 37866
Number of extensions: 2205556
Number of successful extensions: 44362
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 617
Number of HSP's successfully gapped in prelim test: 611
Number of HSP's that attempted gapping in prelim test: 26210
Number of HSP's gapped (non-prelim): 11017
length of query: 703
length of database: 18,247,518
effective HSP length: 109
effective length of query: 594
effective length of database: 14,120,124
effective search space: 8387353656
effective search space used: 8387353656
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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