Search of human proteins with 14149997

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14149997 neuroblastoma breakpoint family, member 3 [Homo
sapiens]
         (633 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14149997 neuroblastoma breakpoint family, member 3 [Homo sapi...  1296   0.0  
gi|92110019 hypothetical protein LOC55672 [Homo sapiens]              836   0.0  
gi|239741309 PREDICTED: hypothetical protein XP_002344485 [Homo ...   831   0.0  
gi|169162915 PREDICTED: hypothetical protein LOC728841 [Homo sap...   830   0.0  
gi|83415174 hypothetical protein LOC400818 [Homo sapiens]             828   0.0  
gi|224589132 hypothetical protein LOC100132406 [Homo sapiens]         823   0.0  
gi|157266285 hypothetical protein LOC728936 [Homo sapiens]            818   0.0  
gi|29789405 hypothetical protein LOC284565 [Homo sapiens]             815   0.0  
gi|156071420 hypothetical protein LOC728912 [Homo sapiens]            806   0.0  
gi|119709825 neuroblastoma breakpoint family, member 11-like [Ho...   806   0.0  
gi|7657017 hypothetical protein LOC25832 [Homo sapiens]               703   0.0  
gi|221136844 neuroblastoma breakpoint family, member 6 isoform 1...   467   e-131
gi|221136848 neuroblastoma breakpoint family, member 6 isoform 2...   459   e-129
gi|221218991 neuroblastoma breakpoint family, member 4 [Homo sap...   459   e-129
gi|114158664 hypothetical protein LOC343505 [Homo sapiens]            449   e-126
gi|239741297 PREDICTED: neuroblastoma breakpoint family, member ...   448   e-126
gi|239758011 PREDICTED: hypothetical protein LOC728841, partial ...   160   3e-39
gi|239747446 PREDICTED: similar to Neuroblastoma breakpoint fami...   107   4e-23
gi|239741304 PREDICTED: similar to Neuroblastoma breakpoint fami...   104   3e-22
gi|239741281 PREDICTED: Neuroblastoma breakpoint family member 6...   104   3e-22
gi|239752894 PREDICTED: Neuroblastoma breakpoint family member 6...   101   2e-21
gi|157311604 phosphodiesterase 4D interacting protein isoform 1 ...    79   1e-14
gi|7657138 golgi integral membrane protein 4 [Homo sapiens]            50   5e-06
gi|148746195 trichohyalin [Homo sapiens]                               47   4e-05
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...    46   9e-05
gi|68077166 DnaJ homology subfamily A member 5 isoform 2 [Homo s...    46   9e-05
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]                    46   1e-04
gi|115334679 retinoblastoma-binding protein 1 isoform III [Homo ...    45   2e-04
gi|115334673 retinoblastoma-binding protein 1 isoform II [Homo s...    45   2e-04
gi|115334677 retinoblastoma-binding protein 1 isoform I [Homo sa...    45   2e-04

>gi|14149997 neuroblastoma breakpoint family, member 3 [Homo
           sapiens]
          Length = 633

 Score = 1296 bits (3354), Expect = 0.0
 Identities = 633/633 (100%), Positives = 633/633 (100%)

Query: 1   MPLTPTVQGFQWTLRGPDVETSPFGAPRAASHGVGRHQELRDPTVPGPTSSATNVSMVVS 60
           MPLTPTVQGFQWTLRGPDVETSPFGAPRAASHGVGRHQELRDPTVPGPTSSATNVSMVVS
Sbjct: 1   MPLTPTVQGFQWTLRGPDVETSPFGAPRAASHGVGRHQELRDPTVPGPTSSATNVSMVVS 60

Query: 61  AGPWSGEKAEMNILEINKKSRPQLAENKQQFRNLKQKCLVTQVAYFLANRQNNYDYEDCK 120
           AGPWSGEKAEMNILEINKKSRPQLAENKQQFRNLKQKCLVTQVAYFLANRQNNYDYEDCK
Sbjct: 61  AGPWSGEKAEMNILEINKKSRPQLAENKQQFRNLKQKCLVTQVAYFLANRQNNYDYEDCK 120

Query: 121 DLIKSMLRDERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQLREKLQEGRDASRSLN 180
           DLIKSMLRDERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQLREKLQEGRDASRSLN
Sbjct: 121 DLIKSMLRDERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQLREKLQEGRDASRSLN 180

Query: 181 QHLQALLTPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAEKVQE 240
           QHLQALLTPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAEKVQE
Sbjct: 181 QHLQALLTPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAEKVQE 240

Query: 241 LYAPREVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTLIDSS 300
           LYAPREVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTLIDSS
Sbjct: 241 LYAPREVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTLIDSS 300

Query: 301 SHDEWLDAVCIIPENESDHEQEEEKGPVSPRNLQESEEEEAPQESWDEGDWTLSIPPDMS 360
           SHDEWLDAVCIIPENESDHEQEEEKGPVSPRNLQESEEEEAPQESWDEGDWTLSIPPDMS
Sbjct: 301 SHDEWLDAVCIIPENESDHEQEEEKGPVSPRNLQESEEEEAPQESWDEGDWTLSIPPDMS 360

Query: 361 ASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDS 420
           ASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDS
Sbjct: 361 ASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDS 420

Query: 421 LDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLS 480
           LDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLS
Sbjct: 421 LDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLS 480

Query: 481 RELPEVVEPEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKY 540
           RELPEVVEPEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKY
Sbjct: 481 RELPEVVEPEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKY 540

Query: 541 QEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEE 600
           QEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEE
Sbjct: 541 QEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEE 600

Query: 601 QDVSLALDVDNRFFTLTVIRHHLAFQMGVIFPH 633
           QDVSLALDVDNRFFTLTVIRHHLAFQMGVIFPH
Sbjct: 601 QDVSLALDVDNRFFTLTVIRHHLAFQMGVIFPH 633


>gi|92110019 hypothetical protein LOC55672 [Homo sapiens]
          Length = 1214

 Score =  836 bits (2159), Expect = 0.0
 Identities = 433/577 (75%), Positives = 479/577 (83%), Gaps = 4/577 (0%)

Query: 37   HQELRDPT----VPGPTSSATNVSMVVSAGPWSGEKAEMNILEINKKSRPQLAENKQQFR 92
            H E +D      VPGPTSSATNVSMVVSAGP S EKAEMNILE+N+K RPQLAE KQQFR
Sbjct: 519  HDECQDAVNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEMNEKLRPQLAEKKQQFR 578

Query: 93   NLKQKCLVTQVAYFLANRQNNYDYEDCKDLIKSMLRDERLLTEEKLAEELGQAEELRQYK 152
            NLK+KC VTQ+A FLAN+QN Y YE+CKDLIKS+LR+ER   EEKLAE+L QAEELRQYK
Sbjct: 579  NLKEKCFVTQLACFLANQQNKYKYEECKDLIKSVLRNERQFKEEKLAEQLKQAEELRQYK 638

Query: 153  VLVHSQERELTQLREKLQEGRDASRSLNQHLQALLTPDEPDNSQGRDLREQLAEGCRLAQ 212
            VLVHSQERELTQLREKL+EGRDASRSLNQHLQALLTPDEPD SQG+DL+EQLAEGCRLAQ
Sbjct: 639  VLVHSQERELTQLREKLREGRDASRSLNQHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQ 698

Query: 213  HLVQKLSPENDDDEDEDVKVEEAEKVQELYAPREVQKAEEKEVPEDSLEECAITCSNSHH 272
             L QKLSPEND+D DEDV+VE AEKVQ+  APRE+QKAEEKEVPEDSLEECAITCSNSH 
Sbjct: 699  QLFQKLSPENDNDHDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHG 758

Query: 273  PCESNQPYGNTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPRN 332
            P +SNQP+  T+ITFEED+VDSTLI SSSH EW DAV IIPENESD E+EEEKGPVSPRN
Sbjct: 759  PYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRN 818

Query: 333  LQESEEEEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQV 392
            LQESEEEE PQESWDEG  TLSIPP+M ASYQS   TFHS+EEQQV +A+DIG H  DQV
Sbjct: 819  LQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSGTFHSLEEQQVCMAVDIGGHRWDQV 878

Query: 393  KKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQH 452
            KKEDQEAT PRLSRELLDEK PEVLQDSLDR YSTP  YLEL D CQPYRS FY L++Q 
Sbjct: 879  KKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAFYILEQQR 938

Query: 453  LGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDS 512
            +G ALD+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR YSTP  Y ELPD 
Sbjct: 939  VGWALDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 998

Query: 513  CQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLD 572
             QPY S  YSLEE+++G +LDVD I+K QE EEDQ PPCPRL+  L+EA EPEVLQDSLD
Sbjct: 999  GQPYRSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEAVEPEVLQDSLD 1058

Query: 573  RCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
            RCYST S+  +   S   Y S+FY+ EE+ V  +LDV
Sbjct: 1059 RCYSTPSSCLEQPDSCLPYGSSFYALEEKHVGFSLDV 1095



 Score =  477 bits (1227), Expect = e-134
 Identities = 311/631 (49%), Positives = 385/631 (61%), Gaps = 66/631 (10%)

Query: 37  HQELRDPT----VPGPTSSATNVSMVVSAGPWSGEKAEMNILEINKKSRPQLAENKQQFR 92
           H E +D      VPGPTSSATNVSMVVSAGP S EKAEMNILE+N+K RPQLAE KQQFR
Sbjct: 248 HDECQDAVNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEMNEKLRPQLAEKKQQFR 307

Query: 93  NLKQKCLVTQVAYFLANRQNNYDYEDCKDLIKSMLRDERLLTEEKLAEELGQAEELRQYK 152
           NLK+KC VTQ+A FLAN+QN Y YE+C+DLIKSMLR+ER   EEKLAE+L QAEELRQYK
Sbjct: 308 NLKEKCFVTQLAGFLANQQNKYKYEECEDLIKSMLRNERQFKEEKLAEQLKQAEELRQYK 367

Query: 153 VLVHSQERELTQLREKLQEGRDASRSLNQHLQALLTPDEPDNSQGRDLREQLAEGCRLAQ 212
           VLVHSQERELTQLREKL+EGRDASRSLNQHLQALLTPDEPD SQG+DL+EQLAEGCRLAQ
Sbjct: 368 VLVHSQERELTQLREKLREGRDASRSLNQHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQ 427

Query: 213 HLVQKLSPENDDDEDEDVKVEEAEKVQELYAPREVQKAEEKEVPEDSLEECAITCSNSHH 272
           HLVQKLSPEND+DEDEDV+VEEAEKV E  APREVQKAEE +VPEDSLEECAITCSNSH 
Sbjct: 428 HLVQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHG 487

Query: 273 PCESNQPYGNTRITFEEDQVDSTLI--DSSSHDEWLDAVCIIP-----ENESDHEQEEEK 325
           PC+SNQP+ N  ITFEED+V+S L+    SSHDE  DAV I+P      + ++       
Sbjct: 488 PCDSNQPHKNINITFEEDKVNSALVVDRESSHDECQDAVNILPVPGPTSSATNVSMVVSA 547

Query: 326 GPVSPR----NLQESEEEEAPQESWDEGDW---TLSIPPDMSASYQSDRSTFHSVEE--Q 376
           GP+S      N+ E  E+  PQ +  +  +            A + +++   +  EE   
Sbjct: 548 GPLSSEKAEMNILEMNEKLRPQLAEKKQQFRNLKEKCFVTQLACFLANQQNKYKYEECKD 607

Query: 377 QVGLALDIGRHWCDQVKKED-QEATSPRLSRELLDEKEPEVLQ--------DSLDRFYST 427
            +   L   R + ++   E  ++A   R  + L+  +E E+ Q            R  + 
Sbjct: 608 LIKSVLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNQ 667

Query: 428 PFEYLELPDLCQPYRSDFYSLQEQHL-GLALDLDRMKK-----DQEEEED---------Q 472
             + L  PD  +P +S    LQEQ   G  L     +K     D + +ED         Q
Sbjct: 668 HLQALLTPD--EPDKSQGQDLQEQLAEGCRLAQQLFQKLSPENDNDHDEDVQVEVAEKVQ 725

Query: 473 GPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSL 532
               P   RE+ +  E E  +DSL+    T  +     DS QP+     + EE+ V  +L
Sbjct: 726 KSSAP---REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 782

Query: 533 --------------DVDEIEKYQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTT 578
                          + E E   E EE++ P  PR    L E+EE EV Q+S D  YST 
Sbjct: 783 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTL 839

Query: 579 STYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
           S   ++ AS+Q Y   F+S EEQ V +A+D+
Sbjct: 840 SIPPEMLASYQSYSGTFHSLEEQQVCMAVDI 870



 Score =  434 bits (1117), Expect = e-122
 Identities = 280/568 (49%), Positives = 346/568 (60%), Gaps = 68/568 (11%)

Query: 57  MVVSAGPWSGEKAEMNILEINKKSRPQLAENKQQFRNLKQKCLVTQVAYFLANRQNNYDY 116
           MVVSAGPWS EKAE NILEIN+K RPQLAENKQQFRNLK+KC VTQ+A FLANRQ  Y Y
Sbjct: 1   MVVSAGPWSSEKAETNILEINEKLRPQLAENKQQFRNLKEKCFVTQLAGFLANRQKKYKY 60

Query: 117 EDCKDLIKSMLRDERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQLREKLQEGRDAS 176
           E+CKDLIK MLR+ER   EEKLAE+L QAEELRQYKVLVHSQERELTQLREKL+EGRDAS
Sbjct: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120

Query: 177 RSLNQHLQALLTPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAE 236
           RSLNQHLQALLTPDEPD SQG+DL+EQLAEGCRLAQHLVQKLSPEND+DEDEDV+VEEAE
Sbjct: 121 RSLNQHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 180

Query: 237 KVQELYAPREVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTL 296
           KV E  APREVQKAEE +VPEDSLEECAITCSNSH PC+SNQP+ N  ITFEED+V+STL
Sbjct: 181 KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSTL 240

Query: 297 I--DSSSHDEWLDAVCIIP-----ENESDHEQEEEKGPVSPRNLQESEEEEAPQESWDEG 349
           +    SSHDE  DAV I+P      + ++       GP+S      SE+ E      +E 
Sbjct: 241 VVDRESSHDECQDAVNILPVPGPTSSATNVSMVVSAGPLS------SEKAEMNILEMNE- 293

Query: 350 DWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSRELL 409
                + P ++   Q  R+        Q+   L   ++     + ED   +  R  R+  
Sbjct: 294 ----KLRPQLAEKKQQFRNLKEKCFVTQLAGFLANQQNKYKYEECEDLIKSMLRNERQFK 349

Query: 410 DEKEPEVLQDSLD------RFYSTPFEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMK 463
           +EK  E L+ + +        +S   E  +L +  +  R    SL  QHL   L  D   
Sbjct: 350 EEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSL-NQHLQALLTPDEPD 408

Query: 464 KDQEEE-EDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYS 522
           K Q ++ ++Q     RL++ L + + PE+ +D                            
Sbjct: 409 KSQGQDLQEQLAEGCRLAQHLVQKLSPENDED---------------------------- 440

Query: 523 LEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYF 582
            E+E V     V+E EK  E    ++         + +AEE +V +DSL+ C  T S   
Sbjct: 441 -EDEDV----QVEEAEKVLESSAPRE---------VQKAEESKVPEDSLEECAITCSNSH 486

Query: 583 QLHASFQQYRSAFYSFEEQDVSLALDVD 610
               S Q +++   +FEE  V+ AL VD
Sbjct: 487 GPCDSNQPHKNINITFEEDKVNSALVVD 514


>gi|239741309 PREDICTED: hypothetical protein XP_002344485 [Homo
           sapiens]
          Length = 4621

 Score =  831 bits (2147), Expect = 0.0
 Identities = 430/577 (74%), Positives = 479/577 (83%), Gaps = 4/577 (0%)

Query: 37  HQELRDPT----VPGPTSSATNVSMVVSAGPWSGEKAEMNILEINKKSRPQLAENKQQFR 92
           H E +D      VPGPTSSATNVSMVVSAGP S EKAEMNILEIN+K  PQLAE KQQFR
Sbjct: 248 HDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLHPQLAEKKQQFR 307

Query: 93  NLKQKCLVTQVAYFLANRQNNYDYEDCKDLIKSMLRDERLLTEEKLAEELGQAEELRQYK 152
           NLK++C VTQ+A FLAN+Q  Y YE+CKDLIKSMLR+ER   EEKLAE+L QAEELRQYK
Sbjct: 308 NLKERCFVTQLAGFLANQQKKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYK 367

Query: 153 VLVHSQERELTQLREKLQEGRDASRSLNQHLQALLTPDEPDNSQGRDLREQLAEGCRLAQ 212
           VLVH+QERELTQLREKL+EGRDASRSLN+HLQALLTPDEPD SQG+DL+EQLAEGCRLAQ
Sbjct: 368 VLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQ 427

Query: 213 HLVQKLSPENDDDEDEDVKVEEAEKVQELYAPREVQKAEEKEVPEDSLEECAITCSNSHH 272
           HLVQKLSPEND+D+DEDV+VE AEKVQ+  APRE+QKAEEKEVPEDS EECAIT SNSH 
Sbjct: 428 HLVQKLSPENDNDDDEDVQVELAEKVQKSSAPREMQKAEEKEVPEDSQEECAITYSNSHG 487

Query: 273 PCESNQPYGNTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPRN 332
           P +SNQP+  T+ITFEED+VDSTLI SSSH EW DAV IIPENESD E+EEEKGPVSPRN
Sbjct: 488 PYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRN 547

Query: 333 LQESEEEEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQV 392
           LQESEEEE PQESWDEG  TLSIPP+M ASYQS  STFHS+EEQQV +A+DIGRH  DQV
Sbjct: 548 LQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQV 607

Query: 393 KKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQH 452
           KKEDQEAT PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQPYRS FY L++Q 
Sbjct: 608 KKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQR 667

Query: 453 LGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDS 512
           +GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR YSTP  Y ELPD 
Sbjct: 668 IGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 727

Query: 513 CQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLD 572
            QPY S  YSLEE+++G +LDVD  +K QE EEDQ PPCPRL+  L+E  EPEVLQDSLD
Sbjct: 728 GQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 787

Query: 573 RCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
           RCYST S+  +   S Q Y S+FY+ EE+ V  +LDV
Sbjct: 788 RCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 824



 Score =  456 bits (1172), Expect = e-128
 Identities = 295/610 (48%), Positives = 371/610 (60%), Gaps = 68/610 (11%)

Query: 57  MVVSAGPWSGEKAEMNILEINKKSRPQLAENKQQFRNLKQKCLVTQVAYFLANRQNNYDY 116
           MVVSAGPWS EKAEMNILEIN+K RPQLAENKQQF NLK++C VTQ+A FLAN+Q  Y+Y
Sbjct: 1   MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFVTQLAGFLANQQKKYNY 60

Query: 117 EDCKDLIKSMLRDERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQLREKLQEGRDAS 176
           E+CKDLIK MLR+ER   EEKLAE+L QAEELRQYKVLVHSQERELTQLREKL+EGRDAS
Sbjct: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120

Query: 177 RSLNQHLQALLTPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAE 236
           RSLN+HLQALLT DEPD SQG+DL+EQLAEGCRLAQHLVQKLSPEND+DEDEDV+VEEAE
Sbjct: 121 RSLNEHLQALLTLDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 180

Query: 237 KVQELYAPREVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTL 296
           KVQ+  APREVQK EE +VPEDSLEECAITCSNSH PC+SNQP+ N +ITFEED+V+STL
Sbjct: 181 KVQKSSAPREVQKTEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240

Query: 297 I--DSSSHDEWLDAVCIIP-----ENESDHEQEEEKGPVSPR----NLQESEEEEAPQES 345
           +    SSHDE  DA+ I+P      + ++       GP+S      N+ E  E+  PQ +
Sbjct: 241 VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLHPQLA 300

Query: 346 WDEGDW---TLSIPPDMSASYQSDRSTFHSVEE--QQVGLALDIGRHWCDQVKKED-QEA 399
             +  +            A + +++   +  EE    +   L   R + ++   E  ++A
Sbjct: 301 EKKQQFRNLKERCFVTQLAGFLANQQKKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQA 360

Query: 400 TSPRLSRELLDEKEPEVLQ--------DSLDRFYSTPFEYLELPDLCQPYRSDFYSLQE- 450
              R  + L+  +E E+ Q            R  +   + L  PD  +P +S    LQE 
Sbjct: 361 EELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPD--EPDKSQGQDLQEQ 418

Query: 451 --------QHLGLALDLDRMKKDQEE------EEDQGPPCPRLSRELPEVVEPEDLQDSL 496
                   QHL   L  +    D E+      E+ Q    PR  ++  E   PED Q+  
Sbjct: 419 LAEGCRLAQHLVQKLSPENDNDDDEDVQVELAEKVQKSSAPREMQKAEEKEVPEDSQEEC 478

Query: 497 DRWYST---PFSYPELPDSCQPYGSCFYSLEEEHVGFSL--------------DVDEIEK 539
              YS    P+      DS QP+     + EE+ V  +L               + E E 
Sbjct: 479 AITYSNSHGPY------DSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENES 532

Query: 540 YQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFE 599
             E EE++ P  PR    L E+EE EV Q+S D  YST S   ++ AS+Q Y S F+S E
Sbjct: 533 DDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLE 589

Query: 600 EQDVSLALDV 609
           EQ V +A+D+
Sbjct: 590 EQQVCMAVDI 599



 Score =  419 bits (1077), Expect = e-117
 Identities = 245/438 (55%), Positives = 286/438 (65%), Gaps = 30/438 (6%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D D   K +E E+ Q    PR   E+ +  E EV +DSL+ C  T S+     +S QPYG
Sbjct: 4183 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 4242

Query: 282  NTRITFEEDQVDSTL----IDSSSHDEWLDAVCIIPENESDHEQ-EEEKGPVSPRNLQES 336
            ++    EE  V  +L    I+     +         E     ++ EE++ P  PR  +E 
Sbjct: 4243 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 4302

Query: 337  EEEEAPQESWDEGDWTLSIPP---DMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVK 393
             +E+ P+   D  D   S P    +++ S Q  RS F+ +E+Q+VGLA+D+      Q  
Sbjct: 4303 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEV 4362

Query: 394  KEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHL 453
            +EDQ+ + PRLSRELLDEKEPEVLQDSLDR YSTP  YLELPDL QPY S  YSL+EQ+L
Sbjct: 4363 EEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYL 4422

Query: 454  GLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSC 513
            GLALD+DR KKDQEEEEDQGPPCPRLSREL EVVEPE LQDSLDR YSTP S  E PDSC
Sbjct: 4423 GLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSC 4482

Query: 514  QPYGSCFYSLEEEHVGFSLDVDEIEK-------------------YQEGEEDQKPPCPRL 554
            QPYGS FY+LEE+HVGFSLDV EIEK                    +EGEEDQ PPCPRL
Sbjct: 4483 QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQNPPCPRL 4542

Query: 555  NEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDVDNRFF 614
            N VLME EEPEVLQDSLD CYST S YF+L  SFQ YRS FYSFEEQ +S AL VDNRFF
Sbjct: 4543 NGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFF 4602

Query: 615  TLTVIRHHLAFQMGVIFP 632
            TLTV   HL FQMGVIFP
Sbjct: 4603 TLTVTSLHLVFQMGVIFP 4620



 Score =  367 bits (942), Expect = e-101
 Identities = 219/416 (52%), Positives = 265/416 (63%), Gaps = 30/416 (7%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D D   K +E E+ Q    PR   E+ +  E EV +DSL+ C  T S+     +S QPYG
Sbjct: 2456 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2515

Query: 282  NTRITFEEDQVDSTL----IDSSSHDEWLDAVCIIPENESDHEQ-EEEKGPVSPRNLQES 336
            ++    EE  V  +L    I+     +         E     ++ EE++ P  PR  +E 
Sbjct: 2516 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 2575

Query: 337  EEEEAPQESWDEGDWTLSIPP---DMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVK 393
             +E+ P+   D  D + S P    +++ S Q  RS F+ +E+Q+VGLA+D+      Q  
Sbjct: 2576 LDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEV 2635

Query: 394  KEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHL 453
            +EDQ+ + PRLSRELLDEKEPEVLQDSLDR YSTP  YLELPDL QPY S  YSL+EQ+L
Sbjct: 2636 EEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYL 2695

Query: 454  GLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSC 513
            GLALD+DR KKDQEEEEDQGPPCPRLSREL EVVEPE LQDSLDR YSTP S  E PDSC
Sbjct: 2696 GLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSC 2755

Query: 514  QPYGSCFYSLEEEHVGFSLDVDEIEK-------------------YQEGEEDQKPPCPRL 554
            QPYGS FY+LEE+HVGFSLDV EIEK                    +EGEEDQ PPCPRL
Sbjct: 2756 QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRL 2815

Query: 555  NEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDVD 610
            +  L++ +EPEVLQDSLDRCYST S Y +L    Q Y SA YS EEQ + LALDVD
Sbjct: 2816 SRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 2871



 Score =  364 bits (935), Expect = e-100
 Identities = 217/416 (52%), Positives = 265/416 (63%), Gaps = 30/416 (7%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D D   K +E E+ Q    PR   E+ +  E EV +DSL+ C  T S+     +S QPYG
Sbjct: 748  DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 807

Query: 282  NTRITFEEDQVDSTL----IDSSSHDEWLDAVCIIPENESDHEQ-EEEKGPVSPRNLQES 336
            ++    EE  V  +L    I+     +         E     ++ EE++ P  PR  +E 
Sbjct: 808  SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 867

Query: 337  EEEEAPQESWDEGDWTLSIPP---DMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVK 393
             +E+ P+   D  D + S P    +++ S Q  RS F+ +E+Q+VGLA+D+      Q  
Sbjct: 868  LDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEV 927

Query: 394  KEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHL 453
            +EDQ+ + PRLSRELLDEKEPEVLQDSLDR YSTP  YLELPDL QPY S  YSL+EQ+L
Sbjct: 928  EEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYL 987

Query: 454  GLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSC 513
            GLALD+DR KKDQEEEEDQGPPCPRLSREL EVVEPE LQDSLDR YSTP S  E PDSC
Sbjct: 988  GLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSC 1047

Query: 514  QPYGSCFYSLEEEHVGFSLDVDEIEK-------------------YQEGEEDQKPPCPRL 554
            QPYGS FY+LEE+HVGFSLDV EIEK                    +EGEEDQ PPCPRL
Sbjct: 1048 QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRL 1107

Query: 555  NEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDVD 610
            +  L++ + PEVLQDSLDRCYST S   +L  S Q YRSAFY  E+Q V LA+D+D
Sbjct: 1108 SRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMD 1163



 Score =  364 bits (935), Expect = e-100
 Identities = 217/416 (52%), Positives = 265/416 (63%), Gaps = 30/416 (7%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D D   K +E E+ Q    PR   E+ +  E EV +DSL+ C  T S+     +S QPYG
Sbjct: 1236 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1295

Query: 282  NTRITFEEDQVDSTL----IDSSSHDEWLDAVCIIPENESDHEQ-EEEKGPVSPRNLQES 336
            ++    EE  V  +L    I+     +         E     ++ EE++ P  PR  +E 
Sbjct: 1296 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 1355

Query: 337  EEEEAPQESWDEGDWTLSIPP---DMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVK 393
             +E+ P+   D  D + S P    +++ S Q  RS F+ +E+Q+VGLA+D+      Q  
Sbjct: 1356 LDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEV 1415

Query: 394  KEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHL 453
            +EDQ+ + PRLSRELLDEKEPEVLQDSLDR YSTP  YLELPDL QPY S  YSL+EQ+L
Sbjct: 1416 EEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYL 1475

Query: 454  GLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSC 513
            GLALD+DR KKDQEEEEDQGPPCPRLSREL EVVEPE LQDSLDR YSTP S  E PDSC
Sbjct: 1476 GLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSC 1535

Query: 514  QPYGSCFYSLEEEHVGFSLDVDEIEK-------------------YQEGEEDQKPPCPRL 554
            QPYGS FY+LEE+HVGFSLDV EIEK                    +EGEEDQ PPCPRL
Sbjct: 1536 QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRL 1595

Query: 555  NEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDVD 610
            +  L++ + PEVLQDSLDRCYST S   +L  S Q YRSAFY  E+Q V LA+D+D
Sbjct: 1596 SRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMD 1651



 Score =  363 bits (933), Expect = e-100
 Identities = 217/416 (52%), Positives = 264/416 (63%), Gaps = 30/416 (7%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D D   K +E E+ Q    PR   E+ +  E EV +DSL+ C  T S+     +S QPYG
Sbjct: 3207 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 3266

Query: 282  NTRITFEEDQVDSTL----IDSSSHDEWLDAVCIIPENESDHEQ-EEEKGPVSPRNLQES 336
            ++    EE  V  +L    I+     +         E     ++ EE++ P  PR  +E 
Sbjct: 3267 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 3326

Query: 337  EEEEAPQESWDEGDWTLSIPP---DMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVK 393
             +E+ P+   D  D   S P    +++ S Q  RS F+ +E+Q+VGLA+D+      Q  
Sbjct: 3327 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEV 3386

Query: 394  KEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHL 453
            +EDQ+ + PRLSRELLDEKEPEVLQDSLDR YSTP  YLELPDL QPY S  YSL+EQ+L
Sbjct: 3387 EEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYL 3446

Query: 454  GLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSC 513
            GLALD+DR KKDQEEEEDQGPPCPRLSREL EVVEPE LQDSLDR YSTP S  E PDSC
Sbjct: 3447 GLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSC 3506

Query: 514  QPYGSCFYSLEEEHVGFSLDVDEIEK-------------------YQEGEEDQKPPCPRL 554
            QPYGS FY+LEE+HVGFSLDV EIEK                    +EGEEDQ PPCPRL
Sbjct: 3507 QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRL 3566

Query: 555  NEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDVD 610
            +  L++ + PEVLQDSLDRCYST S   +L  S Q YRSAFY  E+Q V LA+D+D
Sbjct: 3567 SRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMD 3622



 Score =  363 bits (933), Expect = e-100
 Identities = 217/416 (52%), Positives = 264/416 (63%), Gaps = 30/416 (7%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D D   K +E E+ Q    PR   E+ +  E EV +DSL+ C  T S+     +S QPYG
Sbjct: 3451 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 3510

Query: 282  NTRITFEEDQVDSTL----IDSSSHDEWLDAVCIIPENESDHEQ-EEEKGPVSPRNLQES 336
            ++    EE  V  +L    I+     +         E     ++ EE++ P  PR  +E 
Sbjct: 3511 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 3570

Query: 337  EEEEAPQESWDEGDWTLSIPP---DMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVK 393
             +E+ P+   D  D   S P    +++ S Q  RS F+ +E+Q+VGLA+D+      Q  
Sbjct: 3571 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEV 3630

Query: 394  KEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHL 453
            +EDQ+ + PRLSRELLDEKEPEVLQDSLDR YSTP  YLELPDL QPY S  YSL+EQ+L
Sbjct: 3631 EEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYL 3690

Query: 454  GLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSC 513
            GLALD+DR KKDQEEEEDQGPPCPRLSREL EVVEPE LQDSLDR YSTP S  E PDSC
Sbjct: 3691 GLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSC 3750

Query: 514  QPYGSCFYSLEEEHVGFSLDVDEIEK-------------------YQEGEEDQKPPCPRL 554
            QPYGS FY+LEE+HVGFSLDV EIEK                    +EGEEDQ PPCPRL
Sbjct: 3751 QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRL 3810

Query: 555  NEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDVD 610
            +  L++ + PEVLQDSLDRCYST S   +L  S Q YRSAFY  E+Q V LA+D+D
Sbjct: 3811 SRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMD 3866



 Score =  363 bits (932), Expect = e-100
 Identities = 217/416 (52%), Positives = 264/416 (63%), Gaps = 30/416 (7%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D D   K +E E+ Q    PR   E+ +  E EV +DSL+ C  T S+     +S QPYG
Sbjct: 3695 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 3754

Query: 282  NTRITFEEDQVDSTL----IDSSSHDEWLDAVCIIPENESDHEQ-EEEKGPVSPRNLQES 336
            ++    EE  V  +L    I+     +         E     ++ EE++ P  PR  +E 
Sbjct: 3755 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 3814

Query: 337  EEEEAPQESWDEGDWTLSIPP---DMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVK 393
             +E+ P+   D  D   S P    +++ S Q  RS F+ +E+Q+VGLA+D+      Q  
Sbjct: 3815 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEV 3874

Query: 394  KEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHL 453
            +EDQ+ + PRLSRELLDEKEPEVLQDSLDR YSTP  YLELPDL QPY S  YSL+EQ+L
Sbjct: 3875 EEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYL 3934

Query: 454  GLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSC 513
            GLALD+DR KKDQEEEEDQGPPCPRLSREL EVVEPE LQDSLDR YSTP S  E PDSC
Sbjct: 3935 GLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSC 3994

Query: 514  QPYGSCFYSLEEEHVGFSLDVDEIEK-------------------YQEGEEDQKPPCPRL 554
            QPYGS FY+LEE+HVGFSLDV EIEK                    +EGEEDQ PPCPRL
Sbjct: 3995 QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQTPPCPRL 4054

Query: 555  NEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDVD 610
            +  L++ + PEVLQDSLDRCYST S   +L  S Q YRSAFY  E+Q V LA+D+D
Sbjct: 4055 SRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMD 4110



 Score =  363 bits (931), Expect = e-100
 Identities = 217/416 (52%), Positives = 264/416 (63%), Gaps = 30/416 (7%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D D   K +E E+ Q    PR   E+ +  E EV +DSL+ C  T S+     +S QPYG
Sbjct: 3939 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 3998

Query: 282  NTRITFEEDQVDSTL----IDSSSHDEWLDAVCIIPENESDHEQ-EEEKGPVSPRNLQES 336
            ++    EE  V  +L    I+     +         E     ++ EE++ P  PR  +E 
Sbjct: 3999 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQTPPCPRLSREL 4058

Query: 337  EEEEAPQESWDEGDWTLSIPP---DMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVK 393
             +E+ P+   D  D   S P    +++ S Q  RS F+ +E+Q+VGLA+D+      Q  
Sbjct: 4059 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEV 4118

Query: 394  KEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHL 453
            +EDQ+ + PRLSRELLDEKEPEVLQDSLDR YSTP  YLELPDL QPY S  YSL+EQ+L
Sbjct: 4119 EEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYL 4178

Query: 454  GLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSC 513
            GLALD+DR KKDQEEEEDQGPPCPRLSREL EVVEPE LQDSLDR YSTP S  E PDSC
Sbjct: 4179 GLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSC 4238

Query: 514  QPYGSCFYSLEEEHVGFSLDVDEIEK-------------------YQEGEEDQKPPCPRL 554
            QPYGS FY+LEE+HVGFSLDV EIEK                    +EGEEDQ PPCPRL
Sbjct: 4239 QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRL 4298

Query: 555  NEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDVD 610
            +  L++ + PEVLQDSLDRCYST S   +L  S Q YRSAFY  E+Q V LA+D+D
Sbjct: 4299 SRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMD 4354



 Score =  362 bits (928), Expect = e-100
 Identities = 219/430 (50%), Positives = 259/430 (60%), Gaps = 58/430 (13%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 2625 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2684

Query: 282  NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSP---RNLQESEE 338
            +   + EE              ++L     +   + D E+EE++GP  P   R L E  E
Sbjct: 2685 SAVYSLEE--------------QYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVE 2730

Query: 339  EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385
             E  Q+S D    T S   +   S Q   S+F+++EE+ VG +LD+G             
Sbjct: 2731 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 2790

Query: 386  ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439
                  R    +  +EDQ    PRLSRELLDEKEPEVLQDSLDR YSTP  YLELPDL Q
Sbjct: 2791 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQ 2850

Query: 440  PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499
            PY S  YSL+EQ+LGLALD+DR KKDQEEEEDQGPPCPRLSREL EVVEPE LQDSLDR 
Sbjct: 2851 PYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRC 2910

Query: 500  YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEK-------------------Y 540
            YSTP S  E PDSCQPYGS FY+LEE+HVGFSLDV EIEK                    
Sbjct: 2911 YSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGR 2970

Query: 541  QEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEE 600
            +EGEEDQ PPCPRL+  L++ +EPEVLQDSLDRCYST S Y +L    Q Y SA YS EE
Sbjct: 2971 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 3030

Query: 601  QDVSLALDVD 610
            Q + LALDVD
Sbjct: 3031 QYLGLALDVD 3040



 Score =  360 bits (925), Expect = 2e-99
 Identities = 216/416 (51%), Positives = 264/416 (63%), Gaps = 30/416 (7%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D D   K +E E+ Q    PR   E+ +  E EV +DSL+ C  T S+     +S QPYG
Sbjct: 1724 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1783

Query: 282  NTRITFEEDQVDSTL----IDSSSHDEWLDAVCIIPENESDHEQ-EEEKGPVSPRNLQES 336
            ++    EE  V  +L    I+     +         E     ++ EE++ P  PR  +E 
Sbjct: 1784 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 1843

Query: 337  EEEEAPQESWDEGDWTLSIPP---DMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVK 393
             +E+ P+   D  D + S P    +++ S Q  RS F+ +E+Q+VGLA+D+      Q  
Sbjct: 1844 LDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEV 1903

Query: 394  KEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHL 453
            +EDQ+ + PRLSRELLDEKEPEVLQDSLDR YSTP  YLELPDL QPY S  YSL+EQ+L
Sbjct: 1904 EEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYL 1963

Query: 454  GLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSC 513
            GLALD+DR KKDQEEEEDQGPPCPRLSREL EVVEPE LQDSLDR YSTP S  E PDSC
Sbjct: 1964 GLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSC 2023

Query: 514  QPYGSCFYSLEEEHVGFSLDVDEIEK-------------------YQEGEEDQKPPCPRL 554
            QPYGS FY+LEE+HVGFSLDV EIEK                    +EGEEDQ PPCPRL
Sbjct: 2024 QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRL 2083

Query: 555  NEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDVD 610
            +  L++ + PEVLQDSLDR YST S   +L  S Q YRSAFY  E+Q V LA+D+D
Sbjct: 2084 SRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMD 2139



 Score =  360 bits (925), Expect = 2e-99
 Identities = 216/416 (51%), Positives = 264/416 (63%), Gaps = 30/416 (7%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D D   K +E E+ Q    PR   E+ +  E EV +DSL+ C  T S+     +S QPYG
Sbjct: 1968 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2027

Query: 282  NTRITFEEDQVDSTL----IDSSSHDEWLDAVCIIPENESDHEQ-EEEKGPVSPRNLQES 336
            ++    EE  V  +L    I+     +         E     ++ EE++ P  PR  +E 
Sbjct: 2028 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 2087

Query: 337  EEEEAPQESWDEGDWTLSIPP---DMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVK 393
             +E+ P+   D  D + S P    +++ S Q  RS F+ +E+Q+VGLA+D+      Q  
Sbjct: 2088 LDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEV 2147

Query: 394  KEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHL 453
            +EDQ+ + PRLSRELLDEKEPEVLQDSLDR YSTP  YLELPDL QPY S  YSL+EQ+L
Sbjct: 2148 EEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYL 2207

Query: 454  GLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSC 513
            GLALD+DR KKDQEEEEDQGPPCPRLSREL EVVEPE LQDSLDR YSTP S  E PDSC
Sbjct: 2208 GLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSC 2267

Query: 514  QPYGSCFYSLEEEHVGFSLDVDEIEK-------------------YQEGEEDQKPPCPRL 554
            QPYGS FY+LEE+HVGFSLDV EIEK                    +EGEEDQ PPCPRL
Sbjct: 2268 QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRL 2327

Query: 555  NEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDVD 610
            +  L++ + PEVLQDSLDR YST S   +L  S Q YRSAFY  E+Q V LA+D+D
Sbjct: 2328 SRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMD 2383



 Score =  360 bits (925), Expect = 2e-99
 Identities = 216/416 (51%), Positives = 264/416 (63%), Gaps = 30/416 (7%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D D   K +E E+ Q    PR   E+ +  E EV +DSL+ C  T S+     +S QPYG
Sbjct: 2212 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2271

Query: 282  NTRITFEEDQVDSTL----IDSSSHDEWLDAVCIIPENESDHEQ-EEEKGPVSPRNLQES 336
            ++    EE  V  +L    I+     +         E     ++ EE++ P  PR  +E 
Sbjct: 2272 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 2331

Query: 337  EEEEAPQESWDEGDWTLSIPP---DMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVK 393
             +E+ P+   D  D + S P    +++ S Q  RS F+ +E+Q+VGLA+D+      Q  
Sbjct: 2332 LDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEV 2391

Query: 394  KEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHL 453
            +EDQ+ + PRLSRELLDEKEPEVLQDSLDR YSTP  YLELPDL QPY S  YSL+EQ+L
Sbjct: 2392 EEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYL 2451

Query: 454  GLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSC 513
            GLALD+DR KKDQEEEEDQGPPCPRLSREL EVVEPE LQDSLDR YSTP S  E PDSC
Sbjct: 2452 GLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSC 2511

Query: 514  QPYGSCFYSLEEEHVGFSLDVDEIEK-------------------YQEGEEDQKPPCPRL 554
            QPYGS FY+LEE+HVGFSLDV EIEK                    +EGEEDQ PPCPRL
Sbjct: 2512 QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRL 2571

Query: 555  NEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDVD 610
            +  L++ + PEVLQDSLDR YST S   +L  S Q YRSAFY  E+Q V LA+D+D
Sbjct: 2572 SRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMD 2627



 Score =  360 bits (923), Expect = 3e-99
 Identities = 216/416 (51%), Positives = 263/416 (63%), Gaps = 30/416 (7%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D D   K +E E+ Q    PR   E+ +  E EV +DSL+ C  T S+     +S QPYG
Sbjct: 992  DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1051

Query: 282  NTRITFEEDQVDSTL----IDSSSHDEWLDAVCIIPENESDHEQ-EEEKGPVSPRNLQES 336
            ++    EE  V  +L    I+     +         E     ++ EE++ P  PR  +E 
Sbjct: 1052 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 1111

Query: 337  EEEEAPQESWDEGDWTLSIPP---DMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVK 393
             +E+ P+   D  D   S P    +++ S Q  RS F+ +E+Q+VGLA+D+      Q  
Sbjct: 1112 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEV 1171

Query: 394  KEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHL 453
            +EDQ+ + PRLSRELLDEKEPEVLQDSLDR YSTP  YLELPDL QPY S  YSL+EQ+L
Sbjct: 1172 EEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYL 1231

Query: 454  GLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSC 513
            GLALD+DR KKDQEEEEDQGPPCPRLSREL EVVEPE LQDSLDR YSTP S  E PDSC
Sbjct: 1232 GLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSC 1291

Query: 514  QPYGSCFYSLEEEHVGFSLDVDEIEK-------------------YQEGEEDQKPPCPRL 554
            QPYGS FY+LEE+HVGFSLDV EIEK                    +EGEEDQ PPCPRL
Sbjct: 1292 QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRL 1351

Query: 555  NEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDVD 610
            +  L++ + PEVLQDSLDR YST S   +L  S Q YRSAFY  E+Q V LA+D+D
Sbjct: 1352 SRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMD 1407



 Score =  360 bits (923), Expect = 3e-99
 Identities = 216/416 (51%), Positives = 263/416 (63%), Gaps = 30/416 (7%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D D   K +E E+ Q    PR   E+ +  E EV +DSL+ C  T S+     +S QPYG
Sbjct: 1480 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1539

Query: 282  NTRITFEEDQVDSTL----IDSSSHDEWLDAVCIIPENESDHEQ-EEEKGPVSPRNLQES 336
            ++    EE  V  +L    I+     +         E     ++ EE++ P  PR  +E 
Sbjct: 1540 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 1599

Query: 337  EEEEAPQESWDEGDWTLSIPP---DMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVK 393
             +E+ P+   D  D   S P    +++ S Q  RS F+ +E+Q+VGLA+D+      Q  
Sbjct: 1600 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEV 1659

Query: 394  KEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHL 453
            +EDQ+ + PRLSRELLDEKEPEVLQDSLDR YSTP  YLELPDL QPY S  YSL+EQ+L
Sbjct: 1660 EEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYL 1719

Query: 454  GLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSC 513
            GLALD+DR KKDQEEEEDQGPPCPRLSREL EVVEPE LQDSLDR YSTP S  E PDSC
Sbjct: 1720 GLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSC 1779

Query: 514  QPYGSCFYSLEEEHVGFSLDVDEIEK-------------------YQEGEEDQKPPCPRL 554
            QPYGS FY+LEE+HVGFSLDV EIEK                    +EGEEDQ PPCPRL
Sbjct: 1780 QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRL 1839

Query: 555  NEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDVD 610
            +  L++ + PEVLQDSLDR YST S   +L  S Q YRSAFY  E+Q V LA+D+D
Sbjct: 1840 SRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMD 1895



 Score =  355 bits (910), Expect = 9e-98
 Identities = 215/422 (50%), Positives = 254/422 (60%), Gaps = 58/422 (13%)

Query: 233  EEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEE 289
            +E E+ Q    PR   E+   +E EV +DSL+ C  T S      +  QPY +   + EE
Sbjct: 2802 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 2861

Query: 290  DQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEEEEAPQESW 346
                          ++L     +   + D E+EE++GP  PR    L E  E E  Q+S 
Sbjct: 2862 --------------QYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSL 2907

Query: 347  DEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG-------------------RH 387
            D    T S   +   S Q   S+F+++EE+ VG +LD+G                   R 
Sbjct: 2908 DRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERR 2967

Query: 388  WCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYS 447
               +  +EDQ    PRLSRELLDEKEPEVLQDSLDR YSTP  YLELPDL QPY S  YS
Sbjct: 2968 RGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYS 3027

Query: 448  LQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYP 507
            L+EQ+LGLALD+DR KKDQEEEEDQGPPCPRLSREL EVVEPE LQDSLDR YSTP S  
Sbjct: 3028 LEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 3087

Query: 508  ELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEK-------------------YQEGEEDQK 548
            E PDSCQPYGS FY+LEE+HVGFSLDV EIEK                    +EGEEDQ 
Sbjct: 3088 EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 3147

Query: 549  PPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALD 608
            PPCPRL+  L++ +EPEVLQDSLDRCYST S Y +L    Q Y SA YS EEQ + LALD
Sbjct: 3148 PPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD 3207

Query: 609  VD 610
            VD
Sbjct: 3208 VD 3209



 Score =  320 bits (821), Expect = 2e-87
 Identities = 193/410 (47%), Positives = 242/410 (59%), Gaps = 39/410 (9%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 673  DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 732

Query: 282  NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEE 338
            +   + EE              ++L     +   + D E+EE++GP  PR    L E  E
Sbjct: 733  SAVYSLEE--------------QYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVE 778

Query: 339  EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385
             E  Q+S D    T S   +   S Q   S+F+++EE+ VG +LD+G             
Sbjct: 779  PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 838

Query: 386  ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439
                  R    +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQ
Sbjct: 839  RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQ 898

Query: 440  PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499
            PYRS FY L++Q +GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR 
Sbjct: 899  PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 958

Query: 500  YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLM 559
            YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD  +K QE EEDQ PPCPRL+  L+
Sbjct: 959  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 1018

Query: 560  EAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
            E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE+ V  +LDV
Sbjct: 1019 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 1068



 Score =  320 bits (821), Expect = 2e-87
 Identities = 193/410 (47%), Positives = 242/410 (59%), Gaps = 39/410 (9%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 917  DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 976

Query: 282  NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEE 338
            +   + EE              ++L     +   + D E+EE++GP  PR    L E  E
Sbjct: 977  SAVYSLEE--------------QYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVE 1022

Query: 339  EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385
             E  Q+S D    T S   +   S Q   S+F+++EE+ VG +LD+G             
Sbjct: 1023 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1082

Query: 386  ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439
                  R    +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQ
Sbjct: 1083 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1142

Query: 440  PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499
            PYRS FY L++Q +GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR 
Sbjct: 1143 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1202

Query: 500  YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLM 559
            YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD  +K QE EEDQ PPCPRL+  L+
Sbjct: 1203 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 1262

Query: 560  EAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
            E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE+ V  +LDV
Sbjct: 1263 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 1312



 Score =  320 bits (821), Expect = 2e-87
 Identities = 193/410 (47%), Positives = 242/410 (59%), Gaps = 39/410 (9%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 1161 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1220

Query: 282  NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSP---RNLQESEE 338
            +   + EE              ++L     +   + D E+EE++GP  P   R L E  E
Sbjct: 1221 SAVYSLEE--------------QYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVE 1266

Query: 339  EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385
             E  Q+S D    T S   +   S Q   S+F+++EE+ VG +LD+G             
Sbjct: 1267 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1326

Query: 386  ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439
                  R    +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQ
Sbjct: 1327 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQ 1386

Query: 440  PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499
            PYRS FY L++Q +GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR 
Sbjct: 1387 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1446

Query: 500  YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLM 559
            YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD  +K QE EEDQ PPCPRL+  L+
Sbjct: 1447 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 1506

Query: 560  EAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
            E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE+ V  +LDV
Sbjct: 1507 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 1556



 Score =  320 bits (821), Expect = 2e-87
 Identities = 193/410 (47%), Positives = 242/410 (59%), Gaps = 39/410 (9%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 1405 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1464

Query: 282  NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEE 338
            +   + EE              ++L     +   + D E+EE++GP  PR    L E  E
Sbjct: 1465 SAVYSLEE--------------QYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVE 1510

Query: 339  EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385
             E  Q+S D    T S   +   S Q   S+F+++EE+ VG +LD+G             
Sbjct: 1511 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1570

Query: 386  ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439
                  R    +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQ
Sbjct: 1571 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1630

Query: 440  PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499
            PYRS FY L++Q +GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR 
Sbjct: 1631 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1690

Query: 500  YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLM 559
            YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD  +K QE EEDQ PPCPRL+  L+
Sbjct: 1691 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 1750

Query: 560  EAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
            E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE+ V  +LDV
Sbjct: 1751 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 1800



 Score =  320 bits (821), Expect = 2e-87
 Identities = 193/410 (47%), Positives = 242/410 (59%), Gaps = 39/410 (9%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 1649 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1708

Query: 282  NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEE 338
            +   + EE              ++L     +   + D E+EE++GP  PR    L E  E
Sbjct: 1709 SAVYSLEE--------------QYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVE 1754

Query: 339  EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385
             E  Q+S D    T S   +   S Q   S+F+++EE+ VG +LD+G             
Sbjct: 1755 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1814

Query: 386  ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439
                  R    +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQ
Sbjct: 1815 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQ 1874

Query: 440  PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499
            PYRS FY L++Q +GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR 
Sbjct: 1875 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1934

Query: 500  YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLM 559
            YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD  +K QE EEDQ PPCPRL+  L+
Sbjct: 1935 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 1994

Query: 560  EAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
            E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE+ V  +LDV
Sbjct: 1995 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 2044



 Score =  320 bits (821), Expect = 2e-87
 Identities = 193/410 (47%), Positives = 242/410 (59%), Gaps = 39/410 (9%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 1893 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1952

Query: 282  NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEE 338
            +   + EE              ++L     +   + D E+EE++GP  PR    L E  E
Sbjct: 1953 SAVYSLEE--------------QYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVE 1998

Query: 339  EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385
             E  Q+S D    T S   +   S Q   S+F+++EE+ VG +LD+G             
Sbjct: 1999 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 2058

Query: 386  ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439
                  R    +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQ
Sbjct: 2059 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQ 2118

Query: 440  PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499
            PYRS FY L++Q +GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR 
Sbjct: 2119 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2178

Query: 500  YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLM 559
            YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD  +K QE EEDQ PPCPRL+  L+
Sbjct: 2179 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 2238

Query: 560  EAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
            E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE+ V  +LDV
Sbjct: 2239 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 2288



 Score =  320 bits (821), Expect = 2e-87
 Identities = 193/410 (47%), Positives = 242/410 (59%), Gaps = 39/410 (9%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 2137 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2196

Query: 282  NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSP---RNLQESEE 338
            +   + EE              ++L     +   + D E+EE++GP  P   R L E  E
Sbjct: 2197 SAVYSLEE--------------QYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVE 2242

Query: 339  EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385
             E  Q+S D    T S   +   S Q   S+F+++EE+ VG +LD+G             
Sbjct: 2243 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 2302

Query: 386  ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439
                  R    +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQ
Sbjct: 2303 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQ 2362

Query: 440  PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499
            PYRS FY L++Q +GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR 
Sbjct: 2363 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2422

Query: 500  YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLM 559
            YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD  +K QE EEDQ PPCPRL+  L+
Sbjct: 2423 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 2482

Query: 560  EAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
            E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE+ V  +LDV
Sbjct: 2483 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 2532



 Score =  320 bits (821), Expect = 2e-87
 Identities = 193/410 (47%), Positives = 242/410 (59%), Gaps = 39/410 (9%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 2381 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2440

Query: 282  NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEE 338
            +   + EE              ++L     +   + D E+EE++GP  PR    L E  E
Sbjct: 2441 SAVYSLEE--------------QYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVE 2486

Query: 339  EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385
             E  Q+S D    T S   +   S Q   S+F+++EE+ VG +LD+G             
Sbjct: 2487 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 2546

Query: 386  ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439
                  R    +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQ
Sbjct: 2547 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQ 2606

Query: 440  PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499
            PYRS FY L++Q +GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR 
Sbjct: 2607 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2666

Query: 500  YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLM 559
            YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD  +K QE EEDQ PPCPRL+  L+
Sbjct: 2667 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 2726

Query: 560  EAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
            E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE+ V  +LDV
Sbjct: 2727 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 2776



 Score =  320 bits (821), Expect = 2e-87
 Identities = 193/410 (47%), Positives = 242/410 (59%), Gaps = 39/410 (9%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 3376 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 3435

Query: 282  NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSP---RNLQESEE 338
            +   + EE              ++L     +   + D E+EE++GP  P   R L E  E
Sbjct: 3436 SAVYSLEE--------------QYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVE 3481

Query: 339  EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385
             E  Q+S D    T S   +   S Q   S+F+++EE+ VG +LD+G             
Sbjct: 3482 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 3541

Query: 386  ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439
                  R    +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQ
Sbjct: 3542 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 3601

Query: 440  PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499
            PYRS FY L++Q +GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR 
Sbjct: 3602 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 3661

Query: 500  YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLM 559
            YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD  +K QE EEDQ PPCPRL+  L+
Sbjct: 3662 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 3721

Query: 560  EAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
            E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE+ V  +LDV
Sbjct: 3722 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 3771



 Score =  320 bits (821), Expect = 2e-87
 Identities = 193/410 (47%), Positives = 242/410 (59%), Gaps = 39/410 (9%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 3620 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 3679

Query: 282  NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEE 338
            +   + EE              ++L     +   + D E+EE++GP  PR    L E  E
Sbjct: 3680 SAVYSLEE--------------QYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVE 3725

Query: 339  EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385
             E  Q+S D    T S   +   S Q   S+F+++EE+ VG +LD+G             
Sbjct: 3726 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 3785

Query: 386  ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439
                  R    +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQ
Sbjct: 3786 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 3845

Query: 440  PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499
            PYRS FY L++Q +GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR 
Sbjct: 3846 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 3905

Query: 500  YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLM 559
            YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD  +K QE EEDQ PPCPRL+  L+
Sbjct: 3906 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 3965

Query: 560  EAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
            E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE+ V  +LDV
Sbjct: 3966 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 4015



 Score =  320 bits (821), Expect = 2e-87
 Identities = 193/410 (47%), Positives = 242/410 (59%), Gaps = 39/410 (9%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 4108 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 4167

Query: 282  NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSP---RNLQESEE 338
            +   + EE              ++L     +   + D E+EE++GP  P   R L E  E
Sbjct: 4168 SAVYSLEE--------------QYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVE 4213

Query: 339  EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385
             E  Q+S D    T S   +   S Q   S+F+++EE+ VG +LD+G             
Sbjct: 4214 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 4273

Query: 386  ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439
                  R    +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQ
Sbjct: 4274 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 4333

Query: 440  PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499
            PYRS FY L++Q +GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR 
Sbjct: 4334 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 4393

Query: 500  YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLM 559
            YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD  +K QE EEDQ PPCPRL+  L+
Sbjct: 4394 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 4453

Query: 560  EAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
            E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE+ V  +LDV
Sbjct: 4454 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 4503



 Score =  320 bits (820), Expect = 3e-87
 Identities = 193/410 (47%), Positives = 242/410 (59%), Gaps = 39/410 (9%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 3864 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 3923

Query: 282  NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSP---RNLQESEE 338
            +   + EE              ++L     +   + D E+EE++GP  P   R L E  E
Sbjct: 3924 SAVYSLEE--------------QYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVE 3969

Query: 339  EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385
             E  Q+S D    T S   +   S Q   S+F+++EE+ VG +LD+G             
Sbjct: 3970 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 4029

Query: 386  ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439
                  R    +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQ
Sbjct: 4030 RRSKKERRRGRKEGEEDQTPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 4089

Query: 440  PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499
            PYRS FY L++Q +GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR 
Sbjct: 4090 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 4149

Query: 500  YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLM 559
            YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD  +K QE EEDQ PPCPRL+  L+
Sbjct: 4150 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 4209

Query: 560  EAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
            E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE+ V  +LDV
Sbjct: 4210 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 4259



 Score =  313 bits (803), Expect = 2e-85
 Identities = 189/402 (47%), Positives = 237/402 (58%), Gaps = 39/402 (9%)

Query: 233  EEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEE 289
            +E E+ Q    PR   E+   +E EV +DSL+ C  T S      +  QPY +   + EE
Sbjct: 3140 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 3199

Query: 290  DQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEEEEAPQESW 346
                          ++L     +   + D E+EE++GP  PR    L E  E E  Q+S 
Sbjct: 3200 --------------QYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSL 3245

Query: 347  DEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG-------------------RH 387
            D    T S   +   S Q   S+F+++EE+ VG +LD+G                   R 
Sbjct: 3246 DRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERR 3305

Query: 388  WCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYS 447
               +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQPYRS FY 
Sbjct: 3306 RGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYV 3365

Query: 448  LQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYP 507
            L++Q +GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR YSTP  Y 
Sbjct: 3366 LEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYL 3425

Query: 508  ELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLMEAEEPEVL 567
            ELPD  QPY S  YSLEE+++G +LDVD  +K QE EEDQ PPCPRL+  L+E  EPEVL
Sbjct: 3426 ELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVL 3485

Query: 568  QDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
            QDSLDRCYST S+  +   S Q Y S+FY+ EE+ V  +LDV
Sbjct: 3486 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 3527



 Score =  313 bits (802), Expect = 3e-85
 Identities = 192/418 (45%), Positives = 244/418 (58%), Gaps = 36/418 (8%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D D   K +E E+ Q    PR   E+ +  E EV +DSL+ C  T S+     +S QPYG
Sbjct: 2869 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2928

Query: 282  NTRITFEEDQVDSTL----IDSSSHDEWLDAVCIIPENESDHEQ-EEEKGPVSPRNLQES 336
            ++    EE  V  +L    I+     +         E     ++ EE++ P  PR  +E 
Sbjct: 2929 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 2988

Query: 337  EEEEAPQESWDEGDWTLSIP------PDMSASYQSDRSTFHSVEEQQVGLALDIGRHWCD 390
             +E+ P+   D  D   S P      PD+   Y S     +S+EEQ +GLALD+ R   D
Sbjct: 2989 LDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSS---AVYSLEEQYLGLALDVDRTKKD 3045

Query: 391  QVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQE 450
            Q ++EDQ    PRLSRELL+  EPEVLQDSLDR YSTP   LE PD CQPY S FY+L+E
Sbjct: 3046 QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE 3105

Query: 451  QHLGLALDLDRMKKD-------------------QEEEEDQGPPCPRLSRELPEVVEPED 491
            +H+G +LD+  ++K                    +E EEDQ PPCPRLSREL +  EPE 
Sbjct: 3106 KHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEV 3165

Query: 492  LQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPC 551
            LQDSLDR YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD  +K QE EEDQ PPC
Sbjct: 3166 LQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPC 3225

Query: 552  PRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
            PRL+  L+E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE+ V  +LDV
Sbjct: 3226 PRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 3283



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 52/218 (23%), Positives = 89/218 (40%), Gaps = 47/218 (21%)

Query: 394 KEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHL 453
           + +++    +L+ +L   K+ E L+      +S   E  +L +  +  R    SL E HL
Sbjct: 72  RNERQFKEEKLAEQL---KQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNE-HL 127

Query: 454 GLALDLDRMKKDQEEE-EDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDS 512
              L LD   K Q ++ ++Q     RL++ L + + PE+ +D                  
Sbjct: 128 QALLTLDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDE----------------- 170

Query: 513 CQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLD 572
                                 DE  + +E E+ QK   PR    + + EE +V +DSL+
Sbjct: 171 ----------------------DEDVQVEEAEKVQKSSAPR---EVQKTEESKVPEDSLE 205

Query: 573 RCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDVD 610
            C  T S       S Q +++   +FEE +V+  L VD
Sbjct: 206 ECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVD 243


>gi|169162915 PREDICTED: hypothetical protein LOC728841 [Homo
           sapiens]
          Length = 3815

 Score =  830 bits (2145), Expect = 0.0
 Identities = 427/565 (75%), Positives = 475/565 (84%)

Query: 45  VPGPTSSATNVSMVVSAGPWSGEKAEMNILEINKKSRPQLAENKQQFRNLKQKCLVTQVA 104
           VPGPTSSATNVSMVVSAGP S EKAEMNILEIN+K  PQLAE KQQFRNLK++C VTQ+A
Sbjct: 9   VPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLHPQLAEKKQQFRNLKERCFVTQLA 68

Query: 105 YFLANRQNNYDYEDCKDLIKSMLRDERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQ 164
            FLAN+Q  Y YE+CKDLIKSMLR+ER   EEKLAE+L QAEELRQYKVLVH+QERELTQ
Sbjct: 69  GFLANQQKKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQ 128

Query: 165 LREKLQEGRDASRSLNQHLQALLTPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDD 224
           LREKL+EGRDASRSLN+HLQALLTPDEPD SQG+DL+EQLAEGCRLAQHLVQKLSPEND+
Sbjct: 129 LREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDN 188

Query: 225 DEDEDVKVEEAEKVQELYAPREVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTR 284
           D+DEDV+VE AEKVQ+  APRE+QKAEEKEVPEDS EECAIT SNSH P +SNQP+  T+
Sbjct: 189 DDDEDVQVELAEKVQKSSAPREMQKAEEKEVPEDSQEECAITYSNSHGPYDSNQPHRKTK 248

Query: 285 ITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPRNLQESEEEEAPQE 344
           ITFEED+VDSTLI SSSH EW DAV IIPENESD E+EEEKGPVSPRNLQESEEEE PQE
Sbjct: 249 ITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQE 308

Query: 345 SWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRL 404
           SWDEG  TLSIPP+M ASYQS  STFHS+EEQQV +A+DIGRH  DQVKKEDQEAT PRL
Sbjct: 309 SWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRL 368

Query: 405 SRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMKK 464
           SRELLDEK PEVLQDSLDR YSTP   LEL D CQPYRS FY L++Q +GLA+D+D ++K
Sbjct: 369 SRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRIGLAVDMDEIEK 428

Query: 465 DQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLE 524
            QE EEDQ P CPRLSREL +  EPE LQDSLDR YSTP  Y ELPD  QPY S  YSLE
Sbjct: 429 YQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLE 488

Query: 525 EEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQL 584
           E+++G +LDVD  +K QE EEDQ PPCPRL+  L+E  EPEVLQDSLDRCYST S+  + 
Sbjct: 489 EQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQ 548

Query: 585 HASFQQYRSAFYSFEEQDVSLALDV 609
             S Q Y S+FY+ EE+ V  +LDV
Sbjct: 549 PDSCQPYGSSFYALEEKHVGFSLDV 573



 Score =  373 bits (958), Expect = e-103
 Identities = 221/428 (51%), Positives = 272/428 (63%), Gaps = 30/428 (7%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D D   K +E E+ Q    PR   E+ +  E EV +DSL+ C  T S+     +S QPYG
Sbjct: 3388 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 3447

Query: 282  NTRITFEEDQVDSTL----IDSSSHDEWLDAVCIIPENESDHEQ-EEEKGPVSPRNLQES 336
            ++    EE  V  +L    I+     +         E     ++ EE++ P  PR  +E 
Sbjct: 3448 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 3507

Query: 337  EEEEAPQESWDEGDWTLSIPP---DMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVK 393
             +E+ P+   D  D + S P    +++ S Q  RS F+ +E+Q+VGLA+D+      Q  
Sbjct: 3508 LDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEV 3567

Query: 394  KEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHL 453
            +EDQ+ + PRLSRELLDEKEPEVLQDSLDR YSTP  YLELPDL QPY S  YSL+EQ+L
Sbjct: 3568 EEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYL 3627

Query: 454  GLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSC 513
            GLALD+DR KKDQEEEEDQGPPCPRLSREL EVVEPE LQDSLDR YSTP S  E PDSC
Sbjct: 3628 GLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSC 3687

Query: 514  QPYGSCFYSLEEEHVGFSLDVDEIEK-------------------YQEGEEDQKPPCPRL 554
            QPYGS FY+LEE+HVGFSLDV EIEK                    +EGEEDQ PPCPRL
Sbjct: 3688 QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRL 3747

Query: 555  NEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDVDNRFF 614
            +  L++ + PEVLQDSLDRCYST S   +L  S Q YRSAFY  E+Q V LA+D+D  + 
Sbjct: 3748 SRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDGEYL 3807

Query: 615  TLTVIRHH 622
            ++ VIR H
Sbjct: 3808 SMKVIRIH 3815



 Score =  366 bits (940), Expect = e-101
 Identities = 219/416 (52%), Positives = 264/416 (63%), Gaps = 30/416 (7%)

Query: 225 DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
           D D   K +E E+ Q    PR   E+ +  E EV +DSL+ C  T S+     +S QPYG
Sbjct: 497 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 556

Query: 282 NTRITFEEDQVDSTL----IDSSSHDEWLDAVCIIPENESDHEQ-EEEKGPVSPRNLQES 336
           ++    EE  V  +L    I+     +         E     ++ EE++ P  PR  +E 
Sbjct: 557 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 616

Query: 337 EEEEAPQESWDEGDWTLSIPP---DMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVK 393
            +E+ P+   D  D   S P    +++ S Q  RS F+ +E+Q+VGLA+D+      Q  
Sbjct: 617 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEV 676

Query: 394 KEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHL 453
           +EDQ+ + PRLSRELLDEKEPEVLQDSLDR YSTP  YLELPDL QPY S  YSL+EQ+L
Sbjct: 677 EEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYL 736

Query: 454 GLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSC 513
           GLALD+DR KKDQEEEEDQGPPCPRLSREL EVVEPE LQDSLDR YSTP S  E PDSC
Sbjct: 737 GLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSC 796

Query: 514 QPYGSCFYSLEEEHVGFSLDVDEIEK-------------------YQEGEEDQKPPCPRL 554
           QPYGS FY+LEE+HVGFSLDV EIEK                    +EGEEDQ PPCPRL
Sbjct: 797 QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRL 856

Query: 555 NEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDVD 610
           +  L++ +EPEVLQDSLDRCYST S Y +L    Q Y SA YS EEQ + LALDVD
Sbjct: 857 SRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 912



 Score =  366 bits (940), Expect = e-101
 Identities = 219/416 (52%), Positives = 264/416 (63%), Gaps = 30/416 (7%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D D   K +E E+ Q    PR   E+ +  E EV +DSL+ C  T S+     +S QPYG
Sbjct: 2224 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2283

Query: 282  NTRITFEEDQVDSTL----IDSSSHDEWLDAVCIIPENESDHEQ-EEEKGPVSPRNLQES 336
            ++    EE  V  +L    I+     +         E     ++ EE++ P  PR  +E 
Sbjct: 2284 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 2343

Query: 337  EEEEAPQESWDEGDWTLSIPP---DMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVK 393
             +E+ P+   D  D   S P    +++ S Q  RS F+ +E+Q+VGLA+D+      Q  
Sbjct: 2344 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEV 2403

Query: 394  KEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHL 453
            +EDQ+ + PRLSRELLDEKEPEVLQDSLDR YSTP  YLELPDL QPY S  YSL+EQ+L
Sbjct: 2404 EEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYL 2463

Query: 454  GLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSC 513
            GLALD+DR KKDQEEEEDQGPPCPRLSREL EVVEPE LQDSLDR YSTP S  E PDSC
Sbjct: 2464 GLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSC 2523

Query: 514  QPYGSCFYSLEEEHVGFSLDVDEIEK-------------------YQEGEEDQKPPCPRL 554
            QPYGS FY+LEE+HVGFSLDV EIEK                    +EGEEDQ PPCPRL
Sbjct: 2524 QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRL 2583

Query: 555  NEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDVD 610
            +  L++ +EPEVLQDSLDRCYST S Y +L    Q Y SA YS EEQ + LALDVD
Sbjct: 2584 SRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 2639



 Score =  366 bits (940), Expect = e-101
 Identities = 219/416 (52%), Positives = 264/416 (63%), Gaps = 30/416 (7%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D D   K +E E+ Q    PR   E+ +  E EV +DSL+ C  T S+     +S QPYG
Sbjct: 2637 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2696

Query: 282  NTRITFEEDQVDSTL----IDSSSHDEWLDAVCIIPENESDHEQ-EEEKGPVSPRNLQES 336
            ++    EE  V  +L    I+     +         E     ++ EE++ P  PR  +E 
Sbjct: 2697 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 2756

Query: 337  EEEEAPQESWDEGDWTLSIPP---DMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVK 393
             +E+ P+   D  D   S P    +++ S Q  RS F+ +E+Q+VGLA+D+      Q  
Sbjct: 2757 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEV 2816

Query: 394  KEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHL 453
            +EDQ+ + PRLSRELLDEKEPEVLQDSLDR YSTP  YLELPDL QPY S  YSL+EQ+L
Sbjct: 2817 EEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYL 2876

Query: 454  GLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSC 513
            GLALD+DR KKDQEEEEDQGPPCPRLSREL EVVEPE LQDSLDR YSTP S  E PDSC
Sbjct: 2877 GLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSC 2936

Query: 514  QPYGSCFYSLEEEHVGFSLDVDEIEK-------------------YQEGEEDQKPPCPRL 554
            QPYGS FY+LEE+HVGFSLDV EIEK                    +EGEEDQ PPCPRL
Sbjct: 2937 QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRL 2996

Query: 555  NEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDVD 610
            +  L++ +EPEVLQDSLDRCYST S Y +L    Q Y SA YS EEQ + LALDVD
Sbjct: 2997 SRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 3052



 Score =  364 bits (935), Expect = e-100
 Identities = 217/416 (52%), Positives = 265/416 (63%), Gaps = 30/416 (7%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D D   K +E E+ Q    PR   E+ +  E EV +DSL+ C  T S+     +S QPYG
Sbjct: 1980 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2039

Query: 282  NTRITFEEDQVDSTL----IDSSSHDEWLDAVCIIPENESDHEQ-EEEKGPVSPRNLQES 336
            ++    EE  V  +L    I+     +         E     ++ EE++ P  PR  +E 
Sbjct: 2040 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 2099

Query: 337  EEEEAPQESWDEGDWTLSIPP---DMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVK 393
             +E+ P+   D  D + S P    +++ S Q  RS F+ +E+Q+VGLA+D+      Q  
Sbjct: 2100 LDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEV 2159

Query: 394  KEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHL 453
            +EDQ+ + PRLSRELLDEKEPEVLQDSLDR YSTP  YLELPDL QPY S  YSL+EQ+L
Sbjct: 2160 EEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYL 2219

Query: 454  GLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSC 513
            GLALD+DR KKDQEEEEDQGPPCPRLSREL EVVEPE LQDSLDR YSTP S  E PDSC
Sbjct: 2220 GLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSC 2279

Query: 514  QPYGSCFYSLEEEHVGFSLDVDEIEK-------------------YQEGEEDQKPPCPRL 554
            QPYGS FY+LEE+HVGFSLDV EIEK                    +EGEEDQ PPCPRL
Sbjct: 2280 QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRL 2339

Query: 555  NEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDVD 610
            +  L++ + PEVLQDSLDRCYST S   +L  S Q YRSAFY  E+Q V LA+D+D
Sbjct: 2340 SRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMD 2395



 Score =  364 bits (934), Expect = e-100
 Identities = 220/419 (52%), Positives = 261/419 (62%), Gaps = 36/419 (8%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D D   K +E E+ Q    PR   E+ +  E EV +DSL+ C  T S+     +S QPYG
Sbjct: 741  DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 800

Query: 282  NTRITFEEDQVDSTL----IDSSSHDEWLDAVCIIPENESDHEQ-EEEKGPVSPRNLQES 336
            ++    EE  V  +L    I+     +         E     ++ EE++ P  PR  +E 
Sbjct: 801  SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 860

Query: 337  EEEEAPQESWDEGDWTLSIP------PDMSASYQSDRSTFHSVEEQQVGLALDIGRHWCD 390
             +E+ P+   D  D   S P      PD+   Y S     +S+EEQ +GLALD+      
Sbjct: 861  LDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSS---AVYSLEEQYLGLALDVDEIEKY 917

Query: 391  QVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQE 450
            Q  +EDQ+ + PRLSRELLDEKEPEVLQDSLDR YSTP  YLELPDL QPY S  YSL+E
Sbjct: 918  QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 977

Query: 451  QHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELP 510
            Q+LGLALD+DR KKDQEEEEDQGPPCPRLSREL EVVEPE LQDSLDR YSTP S  E P
Sbjct: 978  QYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQP 1037

Query: 511  DSCQPYGSCFYSLEEEHVGFSLDVDEIEK-------------------YQEGEEDQKPPC 551
            DSCQPYGS FY+LEE+HVGFSLDV EIEK                    +EGEEDQ PPC
Sbjct: 1038 DSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPC 1097

Query: 552  PRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDVD 610
            PRL+  L++ +EPEVLQDSLDRCYST S Y +L    Q Y SA YS EEQ + LALDVD
Sbjct: 1098 PRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 1156



 Score =  363 bits (933), Expect = e-100
 Identities = 217/416 (52%), Positives = 264/416 (63%), Gaps = 30/416 (7%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D D   K +E E+ Q    PR   E+ +  E EV +DSL+ C  T S+     +S QPYG
Sbjct: 1492 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1551

Query: 282  NTRITFEEDQVDSTL----IDSSSHDEWLDAVCIIPENESDHEQ-EEEKGPVSPRNLQES 336
            ++    EE  V  +L    I+     +         E     ++ EE++ P  PR  +E 
Sbjct: 1552 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 1611

Query: 337  EEEEAPQESWDEGDWTLSIPP---DMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVK 393
             +E+ P+   D  D   S P    +++ S Q  RS F+ +E+Q+VGLA+D+      Q  
Sbjct: 1612 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEV 1671

Query: 394  KEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHL 453
            +EDQ+ + PRLSRELLDEKEPEVLQDSLDR YSTP  YLELPDL QPY S  YSL+EQ+L
Sbjct: 1672 EEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYL 1731

Query: 454  GLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSC 513
            GLALD+DR KKDQEEEEDQGPPCPRLSREL EVVEPE LQDSLDR YSTP S  E PDSC
Sbjct: 1732 GLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSC 1791

Query: 514  QPYGSCFYSLEEEHVGFSLDVDEIEK-------------------YQEGEEDQKPPCPRL 554
            QPYGS FY+LEE+HVGFSLDV EIEK                    +EGEEDQ PPCPRL
Sbjct: 1792 QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRL 1851

Query: 555  NEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDVD 610
            +  L++ + PEVLQDSLDRCYST S   +L  S Q YRSAFY  E+Q V LA+D+D
Sbjct: 1852 SRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMD 1907



 Score =  362 bits (928), Expect = e-100
 Identities = 219/430 (50%), Positives = 259/430 (60%), Gaps = 58/430 (13%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 910  DVDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 969

Query: 282  NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEE 338
            +   + EE              ++L     +   + D E+EE++GP  PR    L E  E
Sbjct: 970  SAVYSLEE--------------QYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVE 1015

Query: 339  EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385
             E  Q+S D    T S   +   S Q   S+F+++EE+ VG +LD+G             
Sbjct: 1016 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1075

Query: 386  ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439
                  R    +  +EDQ    PRLSRELLDEKEPEVLQDSLDR YSTP  YLELPDL Q
Sbjct: 1076 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQ 1135

Query: 440  PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499
            PY S  YSL+EQ+LGLALD+DR KKDQEEEEDQGPPCPRLSREL EVVEPE LQDSLDR 
Sbjct: 1136 PYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRC 1195

Query: 500  YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEK-------------------Y 540
            YSTP S  E PDSCQPYGS FY+LEE+HVGFSLDV EIEK                    
Sbjct: 1196 YSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGR 1255

Query: 541  QEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEE 600
            +EGEEDQ PPCPRL+  L++ +EPEVLQDSLDRCYST S Y +L    Q Y SA YS EE
Sbjct: 1256 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 1315

Query: 601  QDVSLALDVD 610
            Q + LALDVD
Sbjct: 1316 QYLGLALDVD 1325



 Score =  362 bits (928), Expect = e-100
 Identities = 219/430 (50%), Positives = 259/430 (60%), Gaps = 58/430 (13%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 2806 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2865

Query: 282  NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEE 338
            +   + EE              ++L     +   + D E+EE++GP  PR    L E  E
Sbjct: 2866 SAVYSLEE--------------QYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVE 2911

Query: 339  EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385
             E  Q+S D    T S   +   S Q   S+F+++EE+ VG +LD+G             
Sbjct: 2912 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 2971

Query: 386  ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439
                  R    +  +EDQ    PRLSRELLDEKEPEVLQDSLDR YSTP  YLELPDL Q
Sbjct: 2972 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQ 3031

Query: 440  PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499
            PY S  YSL+EQ+LGLALD+DR KKDQEEEEDQGPPCPRLSREL EVVEPE LQDSLDR 
Sbjct: 3032 PYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRC 3091

Query: 500  YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEK-------------------Y 540
            YSTP S  E PDSCQPYGS FY+LEE+HVGFSLDV EIEK                    
Sbjct: 3092 YSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGR 3151

Query: 541  QEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEE 600
            +EGEEDQ PPCPRL+  L++ +EPEVLQDSLDRCYST S Y +L    Q Y SA YS EE
Sbjct: 3152 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 3211

Query: 601  QDVSLALDVD 610
            Q + LALDVD
Sbjct: 3212 QYLGLALDVD 3221



 Score =  360 bits (923), Expect = 3e-99
 Identities = 216/416 (51%), Positives = 263/416 (63%), Gaps = 30/416 (7%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D D   K +E E+ Q    PR   E+ +  E EV +DSL+ C  T S+     +S QPYG
Sbjct: 1736 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1795

Query: 282  NTRITFEEDQVDSTL----IDSSSHDEWLDAVCIIPENESDHEQ-EEEKGPVSPRNLQES 336
            ++    EE  V  +L    I+     +         E     ++ EE++ P  PR  +E 
Sbjct: 1796 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 1855

Query: 337  EEEEAPQESWDEGDWTLSIPP---DMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVK 393
             +E+ P+   D  D   S P    +++ S Q  RS F+ +E+Q+VGLA+D+      Q  
Sbjct: 1856 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEV 1915

Query: 394  KEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHL 453
            +EDQ+ + PRLSRELLDEKEPEVLQDSLDR YSTP  YLELPDL QPY S  YSL+EQ+L
Sbjct: 1916 EEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYL 1975

Query: 454  GLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSC 513
            GLALD+DR KKDQEEEEDQGPPCPRLSREL EVVEPE LQDSLDR YSTP S  E PDSC
Sbjct: 1976 GLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSC 2035

Query: 514  QPYGSCFYSLEEEHVGFSLDVDEIEK-------------------YQEGEEDQKPPCPRL 554
            QPYGS FY+LEE+HVGFSLDV EIEK                    +EGEEDQ PPCPRL
Sbjct: 2036 QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRL 2095

Query: 555  NEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDVD 610
            +  L++ + PEVLQDSLDR YST S   +L  S Q YRSAFY  E+Q V LA+D+D
Sbjct: 2096 SRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMD 2151



 Score =  359 bits (921), Expect = 5e-99
 Identities = 217/430 (50%), Positives = 259/430 (60%), Gaps = 58/430 (13%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 2393 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2452

Query: 282  NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSP---RNLQESEE 338
            +   + EE              ++L     +   + D E+EE++GP  P   R L E  E
Sbjct: 2453 SAVYSLEE--------------QYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVE 2498

Query: 339  EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385
             E  Q+S D    T S   +   S Q   S+F+++EE+ VG +LD+G             
Sbjct: 2499 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 2558

Query: 386  ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439
                  R    +  +EDQ    PRLSRELLDEKEPEVLQDSLDR YSTP  YLELPDL Q
Sbjct: 2559 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQ 2618

Query: 440  PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499
            PY S  YSL+EQ+LGLALD+DR KKDQEEEEDQGPPCPRLSREL EVVEPE LQDSLDR 
Sbjct: 2619 PYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRC 2678

Query: 500  YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEK-------------------Y 540
            YSTP S  E PDSCQPYGS FY+LEE+HVGFSLDV EIEK                    
Sbjct: 2679 YSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGR 2738

Query: 541  QEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEE 600
            +EGEEDQ PPCPRL+  L++ + PEVLQDSLDRCYST S   +L  S Q YRSAFY  E+
Sbjct: 2739 KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQ 2798

Query: 601  QDVSLALDVD 610
            Q V LA+D+D
Sbjct: 2799 QRVGLAVDMD 2808



 Score =  355 bits (910), Expect = 9e-98
 Identities = 215/422 (50%), Positives = 254/422 (60%), Gaps = 58/422 (13%)

Query: 233  EEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEE 289
            +E E+ Q    PR   E+   +E EV +DSL+ C  T S      +  QPY +   + EE
Sbjct: 1087 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 1146

Query: 290  DQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEEEEAPQESW 346
                          ++L     +   + D E+EE++GP  PR    L E  E E  Q+S 
Sbjct: 1147 --------------QYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSL 1192

Query: 347  DEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG-------------------RH 387
            D    T S   +   S Q   S+F+++EE+ VG +LD+G                   R 
Sbjct: 1193 DRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERR 1252

Query: 388  WCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYS 447
               +  +EDQ    PRLSRELLDEKEPEVLQDSLDR YSTP  YLELPDL QPY S  YS
Sbjct: 1253 RGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYS 1312

Query: 448  LQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYP 507
            L+EQ+LGLALD+DR KKDQEEEEDQGPPCPRLSREL EVVEPE LQDSLDR YSTP S  
Sbjct: 1313 LEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 1372

Query: 508  ELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEK-------------------YQEGEEDQK 548
            E PDSCQPYGS FY+LEE+HVGFSLDV EIEK                    +EGEEDQ 
Sbjct: 1373 EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 1432

Query: 549  PPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALD 608
            PPCPRL+  L++ +EPEVLQDSLDRCYST S Y +L    Q Y SA YS EEQ + LALD
Sbjct: 1433 PPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD 1492

Query: 609  VD 610
            VD
Sbjct: 1493 VD 1494



 Score =  355 bits (910), Expect = 9e-98
 Identities = 215/422 (50%), Positives = 254/422 (60%), Gaps = 58/422 (13%)

Query: 233  EEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEE 289
            +E E+ Q    PR   E+   +E EV +DSL+ C  T S      +  QPY +   + EE
Sbjct: 2983 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 3042

Query: 290  DQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEEEEAPQESW 346
                          ++L     +   + D E+EE++GP  PR    L E  E E  Q+S 
Sbjct: 3043 --------------QYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSL 3088

Query: 347  DEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG-------------------RH 387
            D    T S   +   S Q   S+F+++EE+ VG +LD+G                   R 
Sbjct: 3089 DRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERR 3148

Query: 388  WCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYS 447
               +  +EDQ    PRLSRELLDEKEPEVLQDSLDR YSTP  YLELPDL QPY S  YS
Sbjct: 3149 RGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYS 3208

Query: 448  LQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYP 507
            L+EQ+LGLALD+DR KKDQEEEEDQGPPCPRLSREL EVVEPE LQDSLDR YSTP S  
Sbjct: 3209 LEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 3268

Query: 508  ELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEK-------------------YQEGEEDQK 548
            E PDSCQPYGS FY+LEE+HVGFSLDV EIEK                    +EGEEDQ 
Sbjct: 3269 EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 3328

Query: 549  PPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALD 608
            PPCPRL+  L++ +EPEVLQDSLDRCYST S Y +L    Q Y SA YS EEQ + LALD
Sbjct: 3329 PPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD 3388

Query: 609  VD 610
            VD
Sbjct: 3389 VD 3390



 Score =  328 bits (842), Expect = 7e-90
 Identities = 198/410 (48%), Positives = 245/410 (59%), Gaps = 39/410 (9%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 666  DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 725

Query: 282  NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEE 338
            +   + EE              ++L     +   + D E+EE++GP  PR    L E  E
Sbjct: 726  SAVYSLEE--------------QYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVE 771

Query: 339  EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385
             E  Q+S D    T S   +   S Q   S+F+++EE+ VG +LD+G             
Sbjct: 772  PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 831

Query: 386  ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439
                  R    +  +EDQ    PRLSRELLDEKEPEVLQDSLDR YSTP  YLELPDL Q
Sbjct: 832  RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQ 891

Query: 440  PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499
            PY S  YSL+EQ+LGLALD+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR 
Sbjct: 892  PYSSAVYSLEEQYLGLALDVDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 951

Query: 500  YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLM 559
            YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD  +K QE EEDQ PPCPRL+  L+
Sbjct: 952  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 1011

Query: 560  EAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
            E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE+ V  +LDV
Sbjct: 1012 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 1061



 Score =  320 bits (821), Expect = 2e-87
 Identities = 193/410 (47%), Positives = 242/410 (59%), Gaps = 39/410 (9%)

Query: 225 DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
           D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 422 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 481

Query: 282 NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEE 338
           +   + EE              ++L     +   + D E+EE++GP  PR    L E  E
Sbjct: 482 SAVYSLEE--------------QYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVE 527

Query: 339 EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385
            E  Q+S D    T S   +   S Q   S+F+++EE+ VG +LD+G             
Sbjct: 528 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 587

Query: 386 ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439
                 R    +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQ
Sbjct: 588 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 647

Query: 440 PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499
           PYRS FY L++Q +GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR 
Sbjct: 648 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 707

Query: 500 YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLM 559
           YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD  +K QE EEDQ PPCPRL+  L+
Sbjct: 708 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 767

Query: 560 EAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
           E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE+ V  +LDV
Sbjct: 768 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 817



 Score =  320 bits (821), Expect = 2e-87
 Identities = 193/410 (47%), Positives = 242/410 (59%), Gaps = 39/410 (9%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 1661 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1720

Query: 282  NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEE 338
            +   + EE              ++L     +   + D E+EE++GP  PR    L E  E
Sbjct: 1721 SAVYSLEE--------------QYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVE 1766

Query: 339  EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385
             E  Q+S D    T S   +   S Q   S+F+++EE+ VG +LD+G             
Sbjct: 1767 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1826

Query: 386  ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439
                  R    +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQ
Sbjct: 1827 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1886

Query: 440  PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499
            PYRS FY L++Q +GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR 
Sbjct: 1887 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1946

Query: 500  YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLM 559
            YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD  +K QE EEDQ PPCPRL+  L+
Sbjct: 1947 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 2006

Query: 560  EAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
            E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE+ V  +LDV
Sbjct: 2007 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 2056



 Score =  320 bits (821), Expect = 2e-87
 Identities = 193/410 (47%), Positives = 242/410 (59%), Gaps = 39/410 (9%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 1905 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1964

Query: 282  NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEE 338
            +   + EE              ++L     +   + D E+EE++GP  PR    L E  E
Sbjct: 1965 SAVYSLEE--------------QYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVE 2010

Query: 339  EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385
             E  Q+S D    T S   +   S Q   S+F+++EE+ VG +LD+G             
Sbjct: 2011 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 2070

Query: 386  ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439
                  R    +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQ
Sbjct: 2071 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQ 2130

Query: 440  PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499
            PYRS FY L++Q +GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR 
Sbjct: 2131 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2190

Query: 500  YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLM 559
            YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD  +K QE EEDQ PPCPRL+  L+
Sbjct: 2191 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 2250

Query: 560  EAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
            E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE+ V  +LDV
Sbjct: 2251 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 2300



 Score =  320 bits (821), Expect = 2e-87
 Identities = 193/410 (47%), Positives = 242/410 (59%), Gaps = 39/410 (9%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 2149 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2208

Query: 282  NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSP---RNLQESEE 338
            +   + EE              ++L     +   + D E+EE++GP  P   R L E  E
Sbjct: 2209 SAVYSLEE--------------QYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVE 2254

Query: 339  EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385
             E  Q+S D    T S   +   S Q   S+F+++EE+ VG +LD+G             
Sbjct: 2255 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 2314

Query: 386  ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439
                  R    +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQ
Sbjct: 2315 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2374

Query: 440  PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499
            PYRS FY L++Q +GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR 
Sbjct: 2375 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2434

Query: 500  YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLM 559
            YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD  +K QE EEDQ PPCPRL+  L+
Sbjct: 2435 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 2494

Query: 560  EAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
            E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE+ V  +LDV
Sbjct: 2495 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 2544



 Score =  313 bits (803), Expect = 2e-85
 Identities = 189/402 (47%), Positives = 237/402 (58%), Gaps = 39/402 (9%)

Query: 233  EEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEE 289
            +E E+ Q    PR   E+   +E EV +DSL+ C  T S      +  QPY +   + EE
Sbjct: 1425 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 1484

Query: 290  DQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEEEEAPQESW 346
                          ++L     +   + D E+EE++GP  PR    L E  E E  Q+S 
Sbjct: 1485 --------------QYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSL 1530

Query: 347  DEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG-------------------RH 387
            D    T S   +   S Q   S+F+++EE+ VG +LD+G                   R 
Sbjct: 1531 DRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERR 1590

Query: 388  WCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYS 447
               +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQPYRS FY 
Sbjct: 1591 RGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYV 1650

Query: 448  LQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYP 507
            L++Q +GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR YSTP  Y 
Sbjct: 1651 LEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYL 1710

Query: 508  ELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLMEAEEPEVL 567
            ELPD  QPY S  YSLEE+++G +LDVD  +K QE EEDQ PPCPRL+  L+E  EPEVL
Sbjct: 1711 ELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVL 1770

Query: 568  QDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
            QDSLDRCYST S+  +   S Q Y S+FY+ EE+ V  +LDV
Sbjct: 1771 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 1812



 Score =  313 bits (803), Expect = 2e-85
 Identities = 189/402 (47%), Positives = 237/402 (58%), Gaps = 39/402 (9%)

Query: 233  EEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEE 289
            +E E+ Q    PR   E+   +E EV +DSL+ C  T S      +  QPY +   + EE
Sbjct: 2570 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 2629

Query: 290  DQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEEEEAPQESW 346
                          ++L     +   + D E+EE++GP  PR    L E  E E  Q+S 
Sbjct: 2630 --------------QYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSL 2675

Query: 347  DEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG-------------------RH 387
            D    T S   +   S Q   S+F+++EE+ VG +LD+G                   R 
Sbjct: 2676 DRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERR 2735

Query: 388  WCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYS 447
               +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQPYRS FY 
Sbjct: 2736 RGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYV 2795

Query: 448  LQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYP 507
            L++Q +GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR YSTP  Y 
Sbjct: 2796 LEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYL 2855

Query: 508  ELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLMEAEEPEVL 567
            ELPD  QPY S  YSLEE+++G +LDVD  +K QE EEDQ PPCPRL+  L+E  EPEVL
Sbjct: 2856 ELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVL 2915

Query: 568  QDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
            QDSLDRCYST S+  +   S Q Y S+FY+ EE+ V  +LDV
Sbjct: 2916 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 2957



 Score =  313 bits (803), Expect = 2e-85
 Identities = 189/402 (47%), Positives = 237/402 (58%), Gaps = 39/402 (9%)

Query: 233  EEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEE 289
            +E E+ Q    PR   E+   +E EV +DSL+ C  T S      +  QPY +   + EE
Sbjct: 3321 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 3380

Query: 290  DQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEEEEAPQESW 346
                          ++L     +   + D E+EE++GP  PR    L E  E E  Q+S 
Sbjct: 3381 --------------QYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSL 3426

Query: 347  DEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG-------------------RH 387
            D    T S   +   S Q   S+F+++EE+ VG +LD+G                   R 
Sbjct: 3427 DRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERR 3486

Query: 388  WCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYS 447
               +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQPYRS FY 
Sbjct: 3487 RGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYV 3546

Query: 448  LQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYP 507
            L++Q +GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR YSTP  Y 
Sbjct: 3547 LEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYL 3606

Query: 508  ELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLMEAEEPEVL 567
            ELPD  QPY S  YSLEE+++G +LDVD  +K QE EEDQ PPCPRL+  L+E  EPEVL
Sbjct: 3607 ELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVL 3666

Query: 568  QDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
            QDSLDRCYST S+  +   S Q Y S+FY+ EE+ V  +LDV
Sbjct: 3667 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 3708



 Score =  313 bits (802), Expect = 3e-85
 Identities = 192/418 (45%), Positives = 244/418 (58%), Gaps = 36/418 (8%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D D   K +E E+ Q    PR   E+ +  E EV +DSL+ C  T S+     +S QPYG
Sbjct: 1154 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1213

Query: 282  NTRITFEEDQVDSTL----IDSSSHDEWLDAVCIIPENESDHEQ-EEEKGPVSPRNLQES 336
            ++    EE  V  +L    I+     +         E     ++ EE++ P  PR  +E 
Sbjct: 1214 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 1273

Query: 337  EEEEAPQESWDEGDWTLSIP------PDMSASYQSDRSTFHSVEEQQVGLALDIGRHWCD 390
             +E+ P+   D  D   S P      PD+   Y S     +S+EEQ +GLALD+ R   D
Sbjct: 1274 LDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSS---AVYSLEEQYLGLALDVDRTKKD 1330

Query: 391  QVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQE 450
            Q ++EDQ    PRLSRELL+  EPEVLQDSLDR YSTP   LE PD CQPY S FY+L+E
Sbjct: 1331 QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE 1390

Query: 451  QHLGLALDLDRMKKD-------------------QEEEEDQGPPCPRLSRELPEVVEPED 491
            +H+G +LD+  ++K                    +E EEDQ PPCPRLSREL +  EPE 
Sbjct: 1391 KHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEV 1450

Query: 492  LQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPC 551
            LQDSLDR YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD  +K QE EEDQ PPC
Sbjct: 1451 LQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPC 1510

Query: 552  PRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
            PRL+  L+E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE+ V  +LDV
Sbjct: 1511 PRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 1568



 Score =  313 bits (802), Expect = 3e-85
 Identities = 192/418 (45%), Positives = 244/418 (58%), Gaps = 36/418 (8%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D D   K +E E+ Q    PR   E+ +  E EV +DSL+ C  T S+     +S QPYG
Sbjct: 3050 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 3109

Query: 282  NTRITFEEDQVDSTL----IDSSSHDEWLDAVCIIPENESDHEQ-EEEKGPVSPRNLQES 336
            ++    EE  V  +L    I+     +         E     ++ EE++ P  PR  +E 
Sbjct: 3110 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 3169

Query: 337  EEEEAPQESWDEGDWTLSIP------PDMSASYQSDRSTFHSVEEQQVGLALDIGRHWCD 390
             +E+ P+   D  D   S P      PD+   Y S     +S+EEQ +GLALD+ R   D
Sbjct: 3170 LDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSS---AVYSLEEQYLGLALDVDRTKKD 3226

Query: 391  QVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQE 450
            Q ++EDQ    PRLSRELL+  EPEVLQDSLDR YSTP   LE PD CQPY S FY+L+E
Sbjct: 3227 QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE 3286

Query: 451  QHLGLALDLDRMKKD-------------------QEEEEDQGPPCPRLSRELPEVVEPED 491
            +H+G +LD+  ++K                    +E EEDQ PPCPRLSREL +  EPE 
Sbjct: 3287 KHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEV 3346

Query: 492  LQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPC 551
            LQDSLDR YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD  +K QE EEDQ PPC
Sbjct: 3347 LQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPC 3406

Query: 552  PRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
            PRL+  L+E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE+ V  +LDV
Sbjct: 3407 PRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 3464



 Score =  307 bits (787), Expect = 2e-83
 Identities = 187/405 (46%), Positives = 236/405 (58%), Gaps = 45/405 (11%)

Query: 233  EEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEE 289
            +E E+ Q    PR   E+   +  EV +DSL+ C  T S      +S QPY +     E+
Sbjct: 2326 KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQ 2385

Query: 290  DQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPRNLQESEEEEAPQESWDEG 349
             +V    +D             + E E   E EE++ P  PR  +E  +E+ P+   D  
Sbjct: 2386 QRV-GLAVD-------------MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL 2431

Query: 350  DWTLSIP------PDMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPR 403
            D   S P      PD+   Y S     +S+EEQ +GLALD+ R   DQ ++EDQ    PR
Sbjct: 2432 DRCYSTPSGYLELPDLGQPYSS---AVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPR 2488

Query: 404  LSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMK 463
            LSRELL+  EPEVLQDSLDR YSTP   LE PD CQPY S FY+L+E+H+G +LD+  ++
Sbjct: 2489 LSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIE 2548

Query: 464  KD-------------------QEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPF 504
            K                    +E EEDQ PPCPRLSREL +  EPE LQDSLDR YSTP 
Sbjct: 2549 KKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPS 2608

Query: 505  SYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLMEAEEP 564
             Y ELPD  QPY S  YSLEE+++G +LDVD  +K QE EEDQ PPCPRL+  L+E  EP
Sbjct: 2609 GYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEP 2668

Query: 565  EVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
            EVLQDSLDRCYST S+  +   S Q Y S+FY+ EE+ V  +LDV
Sbjct: 2669 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 2713


>gi|83415174 hypothetical protein LOC400818 [Homo sapiens]
          Length = 942

 Score =  828 bits (2140), Expect = 0.0
 Identities = 428/577 (74%), Positives = 481/577 (83%), Gaps = 4/577 (0%)

Query: 37  HQELRDPT----VPGPTSSATNVSMVVSAGPWSGEKAEMNILEINKKSRPQLAENKQQFR 92
           H E +D      VPGPTSSATNVSMVVSAGP S EKAEMNILEIN+K RPQLAE KQQFR
Sbjct: 248 HDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFR 307

Query: 93  NLKQKCLVTQVAYFLANRQNNYDYEDCKDLIKSMLRDERLLTEEKLAEELGQAEELRQYK 152
           NLK+KC +TQ+A FLAN+QN Y YE+CKDLIK MLR+ER   EEKLAE+L QAEELRQYK
Sbjct: 308 NLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYK 367

Query: 153 VLVHSQERELTQLREKLQEGRDASRSLNQHLQALLTPDEPDNSQGRDLREQLAEGCRLAQ 212
           VLVH+QERELTQLREKL+EGRDASRSLN+HLQALLTPDEPD SQG+DL+EQLAEGCRLAQ
Sbjct: 368 VLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQ 427

Query: 213 HLVQKLSPENDDDEDEDVKVEEAEKVQELYAPREVQKAEEKEVPEDSLEECAITCSNSHH 272
           HLVQKLSPEND+D++EDV+VE AEKVQ+  APRE+QKAEEKEVPEDSLEECAIT SNSH 
Sbjct: 428 HLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHG 487

Query: 273 PCESNQPYGNTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPRN 332
           P +SNQP+  T+ITFEED+VDSTLI SSSH E  DAV IIPENESD E+EEEKGPVSPRN
Sbjct: 488 PYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEREDAVHIIPENESDDEEEEEKGPVSPRN 547

Query: 333 LQESEEEEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQV 392
           LQESEEEE PQESWDEG  T SIPP+M ASY+S  STFHS+EEQQV +A+DIGRH  DQV
Sbjct: 548 LQESEEEEVPQESWDEGYSTPSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQV 607

Query: 393 KKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQH 452
           KKEDQEAT PRLSRELLDEK PEVLQDSL R YSTP   LEL D CQPYRS FY L++Q 
Sbjct: 608 KKEDQEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQR 667

Query: 453 LGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDS 512
           +GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSL RWYSTP  YPELPD 
Sbjct: 668 VGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDL 727

Query: 513 CQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLD 572
            QPY S  YSLEE+++G +LD+D I+K QE EEDQ PPCPRL+  L+E  EPEVLQDSLD
Sbjct: 728 GQPYSSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 787

Query: 573 RCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
           RCYST S+  +   S+Q Y S+FY+ EE+ V  +LDV
Sbjct: 788 RCYSTPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDV 824



 Score =  451 bits (1160), Expect = e-127
 Identities = 292/607 (48%), Positives = 369/607 (60%), Gaps = 62/607 (10%)

Query: 57  MVVSAGPWSGEKAEMNILEINKKSRPQLAENKQQFRNLKQKCLVTQVAYFLANRQNNYDY 116
           MVVSAGPWS EKAEMNILEIN+K RPQLAENKQQF NLK++C +TQ+A FLANRQ  Y Y
Sbjct: 1   MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYKY 60

Query: 117 EDCKDLIKSMLRDERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQLREKLQEGRDAS 176
           E+CKDLIK MLR+ER   EEKLAE+L QAEELRQYKVLVHSQERELTQL+EKL+EGRDAS
Sbjct: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDAS 120

Query: 177 RSLNQHLQALLTPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAE 236
           RSLN+HLQALLTPDEPD SQG+DL+EQLAEGCRLAQHLVQKLSPEND+DEDEDV+VEE E
Sbjct: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDE 180

Query: 237 KVQELYAPREVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTL 296
           KV E  APREVQKAEE +V EDSLEECAITCSNSH PC+SNQP+ N +ITFEED+V+STL
Sbjct: 181 KVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240

Query: 297 I--DSSSHDEWLDAVCIIP-----ENESDHEQEEEKGPVSPR----NLQESEEEEAPQES 345
           +    SSHDE  DA+ I+P      + ++       GP+S      N+ E  E+  PQ +
Sbjct: 241 VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLA 300

Query: 346 WDEGDWTLSIPP---DMSASYQSDRSTFHSVEE--QQVGLALDIGRHWCDQVKKED-QEA 399
             +  +            A + +++   +  EE    +   L   R + ++   E  ++A
Sbjct: 301 EKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQA 360

Query: 400 TSPRLSRELLDEKEPEVLQ--------DSLDRFYSTPFEYLELPDLCQPYRSDFYSLQE- 450
              R  + L+  +E E+ Q            R  +   + L  PD  +P +S    LQE 
Sbjct: 361 EELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPD--EPDKSQGQDLQEQ 418

Query: 451 --------QHLGLALDLDRMKKDQEE------EEDQGPPCPRLSRELPEVVEPEDLQDSL 496
                   QHL   L  +    D E+      E+ Q    P   RE+ +  E E  +DSL
Sbjct: 419 LAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAP---REMQKAEEKEVPEDSL 475

Query: 497 DRWYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSL--------------DVDEIEKYQE 542
           +    T  +     DS QP+     + EE+ V  +L               + E E   E
Sbjct: 476 EECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEREDAVHIIPENESDDE 535

Query: 543 GEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQD 602
            EE++ P  PR    L E+EE EV Q+S D  YST S   ++ AS++ Y S F+S EEQ 
Sbjct: 536 EEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTPSIPPEMLASYKSYSSTFHSLEEQQ 592

Query: 603 VSLALDV 609
           V +A+D+
Sbjct: 593 VCMAVDI 599



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 27/78 (34%), Positives = 42/78 (53%), Gaps = 3/78 (3%)

Query: 533 DVDEIEKYQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYR 592
           D DE  + +E E+  + P PR    + +AEE +V +DSL+ C  T S       S Q ++
Sbjct: 169 DEDEDVQVEEDEKVLESPAPR---EVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHK 225

Query: 593 SAFYSFEEQDVSLALDVD 610
           +   +FEE +V+  L VD
Sbjct: 226 NIKITFEEDEVNSTLVVD 243


>gi|224589132 hypothetical protein LOC100132406 [Homo sapiens]
          Length = 3628

 Score =  823 bits (2125), Expect = 0.0
 Identities = 426/577 (73%), Positives = 477/577 (82%), Gaps = 4/577 (0%)

Query: 37  HQELRDPT----VPGPTSSATNVSMVVSAGPWSGEKAEMNILEINKKSRPQLAENKQQFR 92
           H E +D      VPGPTSSATNVSMVVSAGP S EKAEMNILEIN+K RPQLAE KQQFR
Sbjct: 248 HDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFR 307

Query: 93  NLKQKCLVTQVAYFLANRQNNYDYEDCKDLIKSMLRDERLLTEEKLAEELGQAEELRQYK 152
           NLK+KC +TQ++ FLAN+Q  Y YE+CKDLIK MLR+ER   EEKLAE+L QAEELRQYK
Sbjct: 308 NLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYK 367

Query: 153 VLVHSQERELTQLREKLQEGRDASRSLNQHLQALLTPDEPDNSQGRDLREQLAEGCRLAQ 212
           VLVH+QERELTQL+EKL+EGRDASRSLN+HLQALLTP EPD SQG+DL+EQLAEGCRLAQ
Sbjct: 368 VLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQ 427

Query: 213 HLVQKLSPENDDDEDEDVKVEEAEKVQELYAPREVQKAEEKEVPEDSLEECAITCSNSHH 272
           HLVQKLSPEND+D+DEDV+VE AEKVQ+  APRE+QKAEEKEVPEDSLEECAIT SNSH 
Sbjct: 428 HLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHG 487

Query: 273 PCESNQPYGNTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPRN 332
             +SNQP+  T+ITFEED+VDSTLI SSSH EW DAV IIPENESD E+EEEKGPVSPRN
Sbjct: 488 SYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRN 547

Query: 333 LQESEEEEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQV 392
           LQESEEEE PQESWDEG  TLSIPP+M ASYQS  STFHS+EEQQV +A+DIGRH  DQV
Sbjct: 548 LQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQV 607

Query: 393 KKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQH 452
           KKEDQEAT PRLSRELLDEK PEV QDS DR YSTP   LEL D CQPYRS FY L++Q 
Sbjct: 608 KKEDQEATGPRLSRELLDEKGPEVFQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQR 667

Query: 453 LGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDS 512
           +GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR YSTP  Y ELPD 
Sbjct: 668 VGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 727

Query: 513 CQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLD 572
            QPY S  YSLEE+++G +LDVD I+K QE EEDQ PPCPRL+  L+E  EPEVLQDSLD
Sbjct: 728 GQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 787

Query: 573 RCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
           RCYST S+  +   S Q Y S+FY+ EE+ V  +LDV
Sbjct: 788 RCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 824



 Score =  453 bits (1166), Expect = e-127
 Identities = 293/605 (48%), Positives = 367/605 (60%), Gaps = 58/605 (9%)

Query: 57  MVVSAGPWSGEKAEMNILEINKKSRPQLAENKQQFRNLKQKCLVTQVAYFLANRQNNYDY 116
           MVVSAGPWS EKAEMNILEIN+  RPQLAE KQQFRNLK+KC +TQ+A FLANRQ  Y Y
Sbjct: 1   MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60

Query: 117 EDCKDLIKSMLRDERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQLREKLQEGRDAS 176
           E+CKDLIK MLR+ER   EEKLAE+L QAEELRQYKVLVHSQERELTQLREKL+EGRDAS
Sbjct: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120

Query: 177 RSLNQHLQALLTPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAE 236
           RSL +HLQALLTPDEPD SQG+DL+EQLAEGCRLAQHLVQKLSPEND+DEDEDV+VEEAE
Sbjct: 121 RSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 180

Query: 237 KVQELYAPREVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTL 296
           KV E  APREVQKAEE +VPEDSLEECAITCSNSH PC+SNQP+ N +ITFEED+V+STL
Sbjct: 181 KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240

Query: 297 I--DSSSHDEWLDAVCIIP-----ENESDHEQEEEKGPVSPR----NLQESEEEEAPQES 345
           +    SSHDE  DA+ I+P      + ++       GP+S      N+ E  E+  PQ +
Sbjct: 241 VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLA 300

Query: 346 WDEGDW----TLSIPPDMSASYQSDRSTFHSVE-EQQVGLALDIGRHWCDQVKKED-QEA 399
             +  +           +S    + +  +   E +  +   L   R + ++   E  ++A
Sbjct: 301 EKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQA 360

Query: 400 TSPRLSRELLDEKEPEV------LQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQE--- 450
              R  + L+  +E E+      L++  D   S       L    +P +S    LQE   
Sbjct: 361 EELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLA 420

Query: 451 ------QHLGLALDLDRMKKDQEE------EEDQGPPCPRLSRELPEVVEPEDLQDSLDR 498
                 QHL   L  +    D E+      E+ Q    P   RE+ +  E E  +DSL+ 
Sbjct: 421 EGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAP---REMQKAEEKEVPEDSLEE 477

Query: 499 WYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSL--------------DVDEIEKYQEGE 544
              T  +     DS QP+     + EE+ V  +L               + E E   E E
Sbjct: 478 CAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEE 537

Query: 545 EDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVS 604
           E++ P  PR    L E+EE EV Q+S D  YST S   ++ AS+Q Y S F+S EEQ V 
Sbjct: 538 EEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVC 594

Query: 605 LALDV 609
           +A+D+
Sbjct: 595 MAVDI 599



 Score =  375 bits (962), Expect = e-104
 Identities = 226/452 (50%), Positives = 270/452 (59%), Gaps = 58/452 (12%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 3190 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 3249

Query: 282  NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEE 338
            +   + EE              ++L     +   + D E+EE++GP  PR    L E  E
Sbjct: 3250 SAVYSLEE--------------QYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 3295

Query: 339  EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385
             E  Q+S D    T S   +   S Q   S+F+++EE+ VG +LD+G             
Sbjct: 3296 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 3355

Query: 386  ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439
                  R    +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQ
Sbjct: 3356 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQ 3415

Query: 440  PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499
            PYRS FY L++QH+GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR 
Sbjct: 3416 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 3475

Query: 500  YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEK-------------------Y 540
            YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD+IEK                    
Sbjct: 3476 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRGR 3535

Query: 541  QEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEE 600
            +EGEEDQ PPCPRLN VLME EE EVLQDSLDRCYST S YF+L  SFQ YRS FYSFEE
Sbjct: 3536 KEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEE 3595

Query: 601  QDVSLALDVDNRFFTLTVIRHHLAFQMGVIFP 632
            Q +S AL VDNRFFTLTV   HL FQMGVIFP
Sbjct: 3596 QHISFALYVDNRFFTLTVTSLHLVFQMGVIFP 3627



 Score =  369 bits (947), Expect = e-102
 Identities = 234/501 (46%), Positives = 298/501 (59%), Gaps = 46/501 (9%)

Query: 146  EELRQYKVLVHSQERELTQLREKLQEGRDAS---RSLNQHLQA----LLTPD--EPDNSQ 196
            +E+ +Y+ +   Q+    +L  +L + ++      SLN+        L  PD  +P +S 
Sbjct: 1407 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLNRCYSTPSGYLELPDLGQPYSSA 1466

Query: 197  GRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAEKVQELYAPREVQKAEEKEVP 256
               L EQ   G  L    ++K   E ++DED+D               RE+ +  E EV 
Sbjct: 1467 VYSLEEQYL-GLALDVDRIKK-DQEEEEDEDQDPPCPRLS--------RELLEVVEPEVL 1516

Query: 257  EDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTL----IDSSSHDEWLDAVCII 312
            +DSL+ C  T S+     +S QPYG++    EE+ V  +L    I+     +        
Sbjct: 1517 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSK 1576

Query: 313  PENESDHEQ-EEEKGPVSPRNLQESEEEEAPQESWDEGDWTLSIPP---DMSASYQSDRS 368
             E     ++ EE++ P  PR  +E  +E+ P+   D  D   S P    +++ S Q  RS
Sbjct: 1577 KERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRS 1636

Query: 369  TFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTP 428
             F+ +E+Q VGLA+D+      Q  +EDQ+ + PRLSRELLDEKEPEVLQDSLDR YSTP
Sbjct: 1637 AFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTP 1696

Query: 429  FEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVE 488
              YLELPDL QPY S  YSL+EQ+LGLALD+DR+KKDQEEEEDQGPPCPRLSREL EVVE
Sbjct: 1697 SGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 1756

Query: 489  PEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEK--------- 539
            PE LQDSLDR YSTP S  E PDSCQPYGS FY+LEE HVGFSLDV EIEK         
Sbjct: 1757 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 1816

Query: 540  ----------YQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQ 589
                       +EGEEDQ PPCPRL+  L++ + PEVLQDSLDRCYST S   +L  S Q
Sbjct: 1817 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1876

Query: 590  QYRSAFYSFEEQDVSLALDVD 610
             YRSAFY  E+Q V LA+D+D
Sbjct: 1877 PYRSAFYVLEQQHVGLAVDMD 1897



 Score =  365 bits (937), Expect = e-101
 Identities = 232/501 (46%), Positives = 295/501 (58%), Gaps = 48/501 (9%)

Query: 146  EELRQYKVLVHSQE-------RELTQLREK--LQEGRDASRSLNQHLQALLTPDEPDNSQ 196
            +E+ +Y+ +   Q+       REL   +E   LQ+  D   S       L    +P +S 
Sbjct: 2385 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2444

Query: 197  GRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAEKVQELYAPREVQKAEEKEVP 256
               L EQ   G  L    V ++  + +++ED+                RE+ +  E EV 
Sbjct: 2445 VYSLEEQYL-GLALD---VDRIKKDQEEEEDQGPPCPRLS--------RELLEVVEPEVL 2492

Query: 257  EDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTL----IDSSSHDEWLDAVCII 312
            +DSL+ C  T S+     +S QPYG++    EE+ V  +L    I+     +        
Sbjct: 2493 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSK 2552

Query: 313  PENESDHEQ-EEEKGPVSPRNLQESEEEEAPQESWDEGDWTLSIPP---DMSASYQSDRS 368
             E     ++ EE++ P  PR  +E  +E+ P+   D  D   S P    +++ S Q  RS
Sbjct: 2553 KERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRS 2612

Query: 369  TFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTP 428
             F+ +E+Q VGLA+D+      Q  +EDQ+ + PRLSRELLDEKEPEVLQDSLDR YSTP
Sbjct: 2613 AFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTP 2672

Query: 429  FEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVE 488
              YLELPDL QPY S  YSL+EQ+LGLALD+DR+KKDQEEEEDQGPPCPRLSREL EVVE
Sbjct: 2673 SGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2732

Query: 489  PEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEK--------- 539
            PE LQDSLDR YSTP S  E PDSCQPYGS FY+LEE+HVGFSLDV EIEK         
Sbjct: 2733 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 2792

Query: 540  ----------YQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQ 589
                       +EGEEDQ PPCPRL+  L++ + PEVLQDSLDRCYST S   +L  S Q
Sbjct: 2793 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2852

Query: 590  QYRSAFYSFEEQDVSLALDVD 610
             YRSAFY  E+Q V LA+D+D
Sbjct: 2853 PYRSAFYVLEQQHVGLAVDMD 2873



 Score =  365 bits (936), Expect = e-101
 Identities = 232/501 (46%), Positives = 294/501 (58%), Gaps = 48/501 (9%)

Query: 146  EELRQYKVLVHSQE-------RELTQLREK--LQEGRDASRSLNQHLQALLTPDEPDNSQ 196
            +E+ +Y+ +   Q+       REL   +E   LQ+  D   S       L    +P +S 
Sbjct: 1653 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 1712

Query: 197  GRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAEKVQELYAPREVQKAEEKEVP 256
               L EQ   G  L    V ++  + +++ED+                RE+ +  E EV 
Sbjct: 1713 VYSLEEQYL-GLALD---VDRIKKDQEEEEDQGPPCPRLS--------RELLEVVEPEVL 1760

Query: 257  EDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTL----IDSSSHDEWLDAVCII 312
            +DSL+ C  T S+     +S QPYG++    EE+ V  +L    I+     +        
Sbjct: 1761 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSK 1820

Query: 313  PENESDHEQ-EEEKGPVSPRNLQESEEEEAPQESWDEGDWTLSIPP---DMSASYQSDRS 368
             E     ++ EE++ P  PR  +E  +E+ P+   D  D   S P    +++ S Q  RS
Sbjct: 1821 KERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRS 1880

Query: 369  TFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTP 428
             F+ +E+Q VGLA+D+      Q  +EDQ+ + PRLSRELLDEKEPEVLQDSLDR YSTP
Sbjct: 1881 AFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTP 1940

Query: 429  FEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVE 488
              YLELPDL QPY S  YSL+EQ+LGLALD+DR+KKDQEEEEDQGPPCPRLSREL EVVE
Sbjct: 1941 SGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2000

Query: 489  PEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEK--------- 539
            PE LQDSLDR YSTP S  E PDSCQPYGS FY+LEE HVGFSLDV EIEK         
Sbjct: 2001 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 2060

Query: 540  ----------YQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQ 589
                       +EGEEDQ PPCPRL+  L++ + PEVLQDSLDRCYST S   +L  S Q
Sbjct: 2061 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2120

Query: 590  QYRSAFYSFEEQDVSLALDVD 610
             YRSAFY  E+Q V LA+D+D
Sbjct: 2121 PYRSAFYVLEQQHVGLAVDMD 2141



 Score =  365 bits (936), Expect = e-101
 Identities = 232/501 (46%), Positives = 294/501 (58%), Gaps = 48/501 (9%)

Query: 146  EELRQYKVLVHSQE-------RELTQLREK--LQEGRDASRSLNQHLQALLTPDEPDNSQ 196
            +E+ +Y+ +   Q+       REL   +E   LQ+  D   S       L    +P +S 
Sbjct: 1897 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 1956

Query: 197  GRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAEKVQELYAPREVQKAEEKEVP 256
               L EQ   G  L    V ++  + +++ED+                RE+ +  E EV 
Sbjct: 1957 VYSLEEQYL-GLALD---VDRIKKDQEEEEDQGPPCPRLS--------RELLEVVEPEVL 2004

Query: 257  EDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTL----IDSSSHDEWLDAVCII 312
            +DSL+ C  T S+     +S QPYG++    EE+ V  +L    I+     +        
Sbjct: 2005 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSK 2064

Query: 313  PENESDHEQ-EEEKGPVSPRNLQESEEEEAPQESWDEGDWTLSIPP---DMSASYQSDRS 368
             E     ++ EE++ P  PR  +E  +E+ P+   D  D   S P    +++ S Q  RS
Sbjct: 2065 KERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRS 2124

Query: 369  TFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTP 428
             F+ +E+Q VGLA+D+      Q  +EDQ+ + PRLSRELLDEKEPEVLQDSLDR YSTP
Sbjct: 2125 AFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTP 2184

Query: 429  FEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVE 488
              YLELPDL QPY S  YSL+EQ+LGLALD+DR+KKDQEEEEDQGPPCPRLSREL EVVE
Sbjct: 2185 SGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2244

Query: 489  PEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEK--------- 539
            PE LQDSLDR YSTP S  E PDSCQPYGS FY+LEE HVGFSLDV EIEK         
Sbjct: 2245 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 2304

Query: 540  ----------YQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQ 589
                       +EGEEDQ PPCPRL+  L++ + PEVLQDSLDRCYST S   +L  S Q
Sbjct: 2305 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2364

Query: 590  QYRSAFYSFEEQDVSLALDVD 610
             YRSAFY  E+Q V LA+D+D
Sbjct: 2365 PYRSAFYVLEQQHVGLAVDMD 2385



 Score =  365 bits (936), Expect = e-101
 Identities = 232/501 (46%), Positives = 294/501 (58%), Gaps = 48/501 (9%)

Query: 146  EELRQYKVLVHSQE-------RELTQLREK--LQEGRDASRSLNQHLQALLTPDEPDNSQ 196
            +E+ +Y+ +   Q+       REL   +E   LQ+  D   S       L    +P +S 
Sbjct: 2141 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2200

Query: 197  GRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAEKVQELYAPREVQKAEEKEVP 256
               L EQ   G  L    V ++  + +++ED+                RE+ +  E EV 
Sbjct: 2201 VYSLEEQYL-GLALD---VDRIKKDQEEEEDQGPPCPRLS--------RELLEVVEPEVL 2248

Query: 257  EDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTL----IDSSSHDEWLDAVCII 312
            +DSL+ C  T S+     +S QPYG++    EE+ V  +L    I+     +        
Sbjct: 2249 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSK 2308

Query: 313  PENESDHEQ-EEEKGPVSPRNLQESEEEEAPQESWDEGDWTLSIPP---DMSASYQSDRS 368
             E     ++ EE++ P  PR  +E  +E+ P+   D  D   S P    +++ S Q  RS
Sbjct: 2309 KERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRS 2368

Query: 369  TFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTP 428
             F+ +E+Q VGLA+D+      Q  +EDQ+ + PRLSRELLDEKEPEVLQDSLDR YSTP
Sbjct: 2369 AFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTP 2428

Query: 429  FEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVE 488
              YLELPDL QPY S  YSL+EQ+LGLALD+DR+KKDQEEEEDQGPPCPRLSREL EVVE
Sbjct: 2429 SGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2488

Query: 489  PEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEK--------- 539
            PE LQDSLDR YSTP S  E PDSCQPYGS FY+LEE HVGFSLDV EIEK         
Sbjct: 2489 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 2548

Query: 540  ----------YQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQ 589
                       +EGEEDQ PPCPRL+  L++ + PEVLQDSLDRCYST S   +L  S Q
Sbjct: 2549 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2608

Query: 590  QYRSAFYSFEEQDVSLALDVD 610
             YRSAFY  E+Q V LA+D+D
Sbjct: 2609 PYRSAFYVLEQQHVGLAVDMD 2629



 Score =  362 bits (929), Expect = e-100
 Identities = 231/501 (46%), Positives = 294/501 (58%), Gaps = 48/501 (9%)

Query: 146  EELRQYKVLVHSQE-------RELTQLREK--LQEGRDASRSLNQHLQALLTPDEPDNSQ 196
            +E+ +Y+ +   Q+       REL   +E   LQ+  D   S       L    +P +S 
Sbjct: 2629 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2688

Query: 197  GRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAEKVQELYAPREVQKAEEKEVP 256
               L EQ   G  L    V ++  + +++ED+                RE+ +  E EV 
Sbjct: 2689 VYSLEEQYL-GLALD---VDRIKKDQEEEEDQGPPCPRLS--------RELLEVVEPEVL 2736

Query: 257  EDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTL----IDSSSHDEWLDAVCII 312
            +DSL+ C  T S+     +S QPYG++    EE  V  +L    I+     +        
Sbjct: 2737 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSK 2796

Query: 313  PENESDHEQ-EEEKGPVSPRNLQESEEEEAPQESWDEGDWTLSIPP---DMSASYQSDRS 368
             E     ++ EE++ P  PR  +E  +E+ P+   D  D   S P    +++ S Q  RS
Sbjct: 2797 KERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRS 2856

Query: 369  TFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTP 428
             F+ +E+Q VGLA+D+      Q  +EDQ+ + PRLSRELLDEKEPEVLQDSLDR YSTP
Sbjct: 2857 AFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTP 2916

Query: 429  FEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVE 488
              YLELPDL QPY S  YSL+EQ+LGLALD+DR+KKDQEEEEDQGPPCPRLSREL EVVE
Sbjct: 2917 SGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2976

Query: 489  PEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEK--------- 539
            PE LQDSLDR YSTP S  E PDSCQPYGS FY+LEE+HVGFSLDV EIEK         
Sbjct: 2977 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 3036

Query: 540  ----------YQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQ 589
                       +EGEEDQ PPCPRL+  L++ + P+VLQDSLDRCYST S   +L  S Q
Sbjct: 3037 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQ 3096

Query: 590  QYRSAFYSFEEQDVSLALDVD 610
             YRSAFY  E+Q V LA+D+D
Sbjct: 3097 PYRSAFYVLEQQRVGLAVDMD 3117



 Score =  361 bits (927), Expect = e-99
 Identities = 230/501 (45%), Positives = 293/501 (58%), Gaps = 48/501 (9%)

Query: 146  EELRQYKVLVHSQE-------RELTQLREK--LQEGRDASRSLNQHLQALLTPDEPDNSQ 196
            +E+ +Y+ +   Q+       REL   +E   LQ+  D   S       L    +P +S 
Sbjct: 675  DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 734

Query: 197  GRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAEKVQELYAPREVQKAEEKEVP 256
               L EQ   G  L    V ++  + +++ED+                RE+ +  E EV 
Sbjct: 735  VYSLEEQYL-GLALD---VDRIKKDQEEEEDQGPPCPRLS--------RELLEVVEPEVL 782

Query: 257  EDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTL----IDSSSHDEWLDAVCII 312
            +DSL+ C  T S+     +S QPYG++    EE  V  +L    I+     +        
Sbjct: 783  QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSK 842

Query: 313  PENESDHEQ-EEEKGPVSPRNLQESEEEEAPQESWDEGDWTLSIPP---DMSASYQSDRS 368
             E     ++ EE++ P  PR  +E  +E+ P+   D  D   S P    +++ S Q  RS
Sbjct: 843  KERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRS 902

Query: 369  TFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTP 428
             F+ +E+Q+VG A+D+      Q  +EDQ+ + PRLSRELLDEKEPEVLQDSLDR YSTP
Sbjct: 903  AFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTP 962

Query: 429  FEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVE 488
              YLELPDL QPY S  YSL+EQ+LGLALD+DR+KKDQEEEEDQGPPCPRLSREL EVVE
Sbjct: 963  SGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 1022

Query: 489  PEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEK--------- 539
            PE LQDSLDR YSTP S  E PDSCQPYGS FY+LEE+HVGFSLDV EIEK         
Sbjct: 1023 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1082

Query: 540  ----------YQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQ 589
                       +EGEEDQ PPCPRL+  L++ + PEVLQDSLDRCYST S   +L  S Q
Sbjct: 1083 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1142

Query: 590  QYRSAFYSFEEQDVSLALDVD 610
             YRSAFY  E+Q V  A+D+D
Sbjct: 1143 PYRSAFYVLEQQRVGFAVDMD 1163



 Score =  360 bits (924), Expect = 2e-99
 Identities = 212/403 (52%), Positives = 257/403 (63%), Gaps = 39/403 (9%)

Query: 233  EEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEE 289
            +E E+ Q    PR   E+   +  +V +DSL+ C  T S     C+S QPY +     E+
Sbjct: 3048 KEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQ 3107

Query: 290  DQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPRNLQESEEEEAPQESWDEG 349
             +V    +D             + E E   E EE++ P  PR  +E  +E+ P+   D  
Sbjct: 3108 QRV-GLAVD-------------MDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEVLQDSL 3153

Query: 350  DWTLSIPP---DMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSR 406
            D   S P    ++  S Q  RS F+ +E+Q+VGLA+D+      Q  +EDQ+ + PRLSR
Sbjct: 3154 DRCYSTPSGCLELCDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSR 3213

Query: 407  ELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMKKDQ 466
            ELLDEKEPEVLQDSLDR YSTP  YLELPDL QPY S  YSL+EQ+LGLALD+DR+KKDQ
Sbjct: 3214 ELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQ 3273

Query: 467  EEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLEEE 526
            EEEEDQGPPCPRLSREL EVVEPE LQDSLDR YSTP S  E PDSCQPYGS FY+LEE+
Sbjct: 3274 EEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEK 3333

Query: 527  HVGFSLDVDEIEK-------------------YQEGEEDQKPPCPRLNEVLMEAEEPEVL 567
            HVGFSLDV EIEK                    +EGEEDQ PPCPRL+  L++ + PEVL
Sbjct: 3334 HVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVL 3393

Query: 568  QDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDVD 610
            QDSLDRCYST S   +L  S Q YRSAFY  E+Q V LA+D+D
Sbjct: 3394 QDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQHVGLAVDMD 3436



 Score =  356 bits (913), Expect = 4e-98
 Identities = 227/501 (45%), Positives = 292/501 (58%), Gaps = 48/501 (9%)

Query: 146  EELRQYKVLVHSQE-------RELTQLREK--LQEGRDASRSLNQHLQALLTPDEPDNSQ 196
            +E+ +Y+ +   Q+       REL   +E   LQ+  D   S       L    +P +S 
Sbjct: 919  DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 978

Query: 197  GRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAEKVQELYAPREVQKAEEKEVP 256
               L EQ   G  L    V ++  + +++ED+                RE+ +  E EV 
Sbjct: 979  VYSLEEQYL-GLALD---VDRIKKDQEEEEDQGPPCPRLS--------RELLEVVEPEVL 1026

Query: 257  EDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTL----IDSSSHDEWLDAVCII 312
            +DSL+ C  T S+     +S QPYG++    EE  V  +L    I+     +        
Sbjct: 1027 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSK 1086

Query: 313  PENESDHEQ-EEEKGPVSPRNLQESEEEEAPQESWDEGDWTLSIPP---DMSASYQSDRS 368
             E     ++ EE++ P  PR  +E  +E+ P+   D  D   S P    +++ S Q  RS
Sbjct: 1087 KERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRS 1146

Query: 369  TFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTP 428
             F+ +E+Q+VG A+D+      Q  +EDQ+ + PRLSRELLDEKEPEVLQDSLDR YSTP
Sbjct: 1147 AFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTP 1206

Query: 429  FEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVE 488
              YLELPDL QPY S  YSL+EQ+LGLALD+DR+KKD+EEEEDQ PPCPRLSREL EVV 
Sbjct: 1207 SGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVA 1266

Query: 489  PEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEK--------- 539
            PE LQDSLDR YSTP S  E PDSCQPYGS FY+LEE+HVGFSLDV EIEK         
Sbjct: 1267 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1326

Query: 540  ----------YQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQ 589
                       +EGEEDQ PPCPRL+  L++ + PEVLQDSLDRCYST S   +L  S Q
Sbjct: 1327 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1386

Query: 590  QYRSAFYSFEEQDVSLALDVD 610
             YRSAFY  E+Q V +A+D+D
Sbjct: 1387 PYRSAFYVLEQQRVGMAVDMD 1407



 Score =  325 bits (833), Expect = 8e-89
 Identities = 209/481 (43%), Positives = 277/481 (57%), Gaps = 29/481 (6%)

Query: 146  EELRQYKVLVHSQE-------RELTQLREK--LQEGRDASRSLNQHLQALLTPDEPDNSQ 196
            +E+ +Y+ +   Q+       REL   +E   LQ+  D   S       L    +P +S 
Sbjct: 2873 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2932

Query: 197  GRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAEKVQELYAPREVQKAEEKEVP 256
               L EQ   G  L    V ++  + +++ED+                RE+ +  E EV 
Sbjct: 2933 VYSLEEQYL-GLALD---VDRIKKDQEEEEDQGPPCPRLS--------RELLEVVEPEVL 2980

Query: 257  EDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTL----IDSSSHDEWLDAVCII 312
            +DSL+ C  T S+     +S QPYG++    EE  V  +L    I+     +        
Sbjct: 2981 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSK 3040

Query: 313  PENESDHEQ-EEEKGPVSPRNLQESEEEEAPQESWDEGDWTLSIPP---DMSASYQSDRS 368
             E     ++ EE++ P  PR  +E  +E+ P+   D  D   S P    ++  S Q  RS
Sbjct: 3041 KERRRGRKEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQPYRS 3100

Query: 369  TFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTP 428
             F+ +E+Q+VGLA+D+      Q  +EDQ+ + PRLSRELLDEK PEVLQDSLDR YSTP
Sbjct: 3101 AFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEVLQDSLDRCYSTP 3160

Query: 429  FEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVE 488
               LEL D CQPYRS FY L++Q +GLA+D+D ++K QE EEDQ P CPRLSREL +  E
Sbjct: 3161 SGCLELCDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKE 3220

Query: 489  PEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQK 548
            PE LQDSLDR YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD I+K QE EEDQ 
Sbjct: 3221 PEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQG 3280

Query: 549  PPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALD 608
            PPCPRL+  L+E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE+ V  +LD
Sbjct: 3281 PPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLD 3340

Query: 609  V 609
            V
Sbjct: 3341 V 3341



 Score =  324 bits (831), Expect = 1e-88
 Identities = 195/410 (47%), Positives = 244/410 (59%), Gaps = 39/410 (9%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 2627 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2686

Query: 282  NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEE 338
            +   + EE              ++L     +   + D E+EE++GP  PR    L E  E
Sbjct: 2687 SAVYSLEE--------------QYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2732

Query: 339  EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385
             E  Q+S D    T S   +   S Q   S+F+++EE+ VG +LD+G             
Sbjct: 2733 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 2792

Query: 386  ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439
                  R    +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQ
Sbjct: 2793 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2852

Query: 440  PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499
            PYRS FY L++QH+GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR 
Sbjct: 2853 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2912

Query: 500  YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLM 559
            YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD I+K QE EEDQ PPCPRL+  L+
Sbjct: 2913 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 2972

Query: 560  EAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
            E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE+ V  +LDV
Sbjct: 2973 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 3022



 Score =  324 bits (830), Expect = 2e-88
 Identities = 195/410 (47%), Positives = 243/410 (59%), Gaps = 39/410 (9%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 2383 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2442

Query: 282  NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEE 338
            +   + EE              ++L     +   + D E+EE++GP  PR    L E  E
Sbjct: 2443 SAVYSLEE--------------QYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2488

Query: 339  EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385
             E  Q+S D    T S   +   S Q   S+F+++EE  VG +LD+G             
Sbjct: 2489 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 2548

Query: 386  ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439
                  R    +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQ
Sbjct: 2549 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2608

Query: 440  PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499
            PYRS FY L++QH+GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR 
Sbjct: 2609 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2668

Query: 500  YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLM 559
            YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD I+K QE EEDQ PPCPRL+  L+
Sbjct: 2669 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 2728

Query: 560  EAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
            E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE+ V  +LDV
Sbjct: 2729 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 2778



 Score =  323 bits (829), Expect = 2e-88
 Identities = 195/410 (47%), Positives = 242/410 (59%), Gaps = 39/410 (9%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 1651 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1710

Query: 282  NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEE 338
            +   + EE              ++L     +   + D E+EE++GP  PR    L E  E
Sbjct: 1711 SAVYSLEE--------------QYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 1756

Query: 339  EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385
             E  Q+S D    T S   +   S Q   S+F+++EE  VG +LD+G             
Sbjct: 1757 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 1816

Query: 386  ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439
                  R    +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQ
Sbjct: 1817 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1876

Query: 440  PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499
            PYRS FY L++QH+GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR 
Sbjct: 1877 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1936

Query: 500  YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLM 559
            YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD I+K QE EEDQ PPCPRL+  L+
Sbjct: 1937 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 1996

Query: 560  EAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
            E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE  V  +LDV
Sbjct: 1997 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDV 2046



 Score =  323 bits (829), Expect = 2e-88
 Identities = 195/410 (47%), Positives = 242/410 (59%), Gaps = 39/410 (9%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 1895 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1954

Query: 282  NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEE 338
            +   + EE              ++L     +   + D E+EE++GP  PR    L E  E
Sbjct: 1955 SAVYSLEE--------------QYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2000

Query: 339  EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385
             E  Q+S D    T S   +   S Q   S+F+++EE  VG +LD+G             
Sbjct: 2001 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 2060

Query: 386  ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439
                  R    +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQ
Sbjct: 2061 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2120

Query: 440  PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499
            PYRS FY L++QH+GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR 
Sbjct: 2121 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2180

Query: 500  YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLM 559
            YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD I+K QE EEDQ PPCPRL+  L+
Sbjct: 2181 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 2240

Query: 560  EAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
            E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE  V  +LDV
Sbjct: 2241 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDV 2290



 Score =  323 bits (829), Expect = 2e-88
 Identities = 195/410 (47%), Positives = 242/410 (59%), Gaps = 39/410 (9%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 2139 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2198

Query: 282  NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEE 338
            +   + EE              ++L     +   + D E+EE++GP  PR    L E  E
Sbjct: 2199 SAVYSLEE--------------QYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2244

Query: 339  EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385
             E  Q+S D    T S   +   S Q   S+F+++EE  VG +LD+G             
Sbjct: 2245 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 2304

Query: 386  ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439
                  R    +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQ
Sbjct: 2305 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2364

Query: 440  PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499
            PYRS FY L++QH+GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR 
Sbjct: 2365 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2424

Query: 500  YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLM 559
            YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD I+K QE EEDQ PPCPRL+  L+
Sbjct: 2425 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 2484

Query: 560  EAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
            E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE  V  +LDV
Sbjct: 2485 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDV 2534



 Score =  323 bits (827), Expect = 4e-88
 Identities = 196/411 (47%), Positives = 244/411 (59%), Gaps = 39/411 (9%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 2871 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2930

Query: 282  NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEE 338
            +   + EE              ++L     +   + D E+EE++GP  PR    L E  E
Sbjct: 2931 SAVYSLEE--------------QYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2976

Query: 339  EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385
             E  Q+S D    T S   +   S Q   S+F+++EE+ VG +LD+G             
Sbjct: 2977 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 3036

Query: 386  ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439
                  R    +  +EDQ    PRLSRELLDEK P+VLQDSLDR YSTP   LEL D CQ
Sbjct: 3037 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQ 3096

Query: 440  PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499
            PYRS FY L++Q +GLA+D+D ++K QE EEDQ P CPRLSREL +   PE LQDSLDR 
Sbjct: 3097 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEVLQDSLDRC 3156

Query: 500  YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLM 559
            YSTP    EL DSCQPY S FY LE++ VG ++D+DEIEKYQE EEDQ P CPRL+  L+
Sbjct: 3157 YSTPSGCLELCDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELL 3216

Query: 560  EAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDVD 610
            + +EPEVLQDSLDRCYST S Y +L    Q Y SA YS EEQ + LALDVD
Sbjct: 3217 DEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 3267



 Score =  320 bits (819), Expect = 3e-87
 Identities = 193/410 (47%), Positives = 242/410 (59%), Gaps = 39/410 (9%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 673  DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 732

Query: 282  NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEE 338
            +   + EE              ++L     +   + D E+EE++GP  PR    L E  E
Sbjct: 733  SAVYSLEE--------------QYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 778

Query: 339  EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385
             E  Q+S D    T S   +   S Q   S+F+++EE+ VG +LD+G             
Sbjct: 779  PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 838

Query: 386  ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439
                  R    +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQ
Sbjct: 839  RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 898

Query: 440  PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499
            PYRS FY L++Q +G A+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR 
Sbjct: 899  PYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 958

Query: 500  YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLM 559
            YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD I+K QE EEDQ PPCPRL+  L+
Sbjct: 959  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 1018

Query: 560  EAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
            E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE+ V  +LDV
Sbjct: 1019 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 1068



 Score =  318 bits (814), Expect = 1e-86
 Identities = 194/411 (47%), Positives = 241/411 (58%), Gaps = 39/411 (9%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL  C  T S      +  QPY 
Sbjct: 1405 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLNRCYSTPSGYLELPDLGQPYS 1464

Query: 282  NTRITFEEDQVDSTL-IDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESE 337
            +   + EE  +   L +D    D+             + E++E++ P  PR    L E  
Sbjct: 1465 SAVYSLEEQYLGLALDVDRIKKDQ-------------EEEEDEDQDPPCPRLSRELLEVV 1511

Query: 338  EEEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------ 385
            E E  Q+S D    T S   +   S Q   S+F+++EE  VG +LD+G            
Sbjct: 1512 EPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRR 1571

Query: 386  -------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLC 438
                   R    +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D C
Sbjct: 1572 GRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSC 1631

Query: 439  QPYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDR 498
            QPYRS FY L++QH+GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR
Sbjct: 1632 QPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDR 1691

Query: 499  WYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVL 558
             YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD I+K QE EEDQ PPCPRL+  L
Sbjct: 1692 CYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSREL 1751

Query: 559  MEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
            +E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE  V  +LDV
Sbjct: 1752 LEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDV 1802



 Score =  317 bits (811), Expect = 3e-86
 Identities = 191/410 (46%), Positives = 241/410 (58%), Gaps = 39/410 (9%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 917  DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 976

Query: 282  NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEE 338
            +   + EE              ++L     +   + D E+EE++GP  PR    L E  E
Sbjct: 977  SAVYSLEE--------------QYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 1022

Query: 339  EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385
             E  Q+S D    T S   +   S Q   S+F+++EE+ VG +LD+G             
Sbjct: 1023 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1082

Query: 386  ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439
                  R    +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQ
Sbjct: 1083 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1142

Query: 440  PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499
            PYRS FY L++Q +G A+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR 
Sbjct: 1143 PYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1202

Query: 500  YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLM 559
            YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD I+K +E EEDQ PPCPRL+  L+
Sbjct: 1203 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELL 1262

Query: 560  EAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
            E   PEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE+ V  +LDV
Sbjct: 1263 EVVAPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 1312



 Score =  312 bits (799), Expect = 7e-85
 Identities = 190/412 (46%), Positives = 241/412 (58%), Gaps = 41/412 (9%)

Query: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 1161 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1220

Query: 282  NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPRNLQESEEEEA 341
            +   + EE              ++L     +   + D E+EE++ P  PR  +E  E  A
Sbjct: 1221 SAVYSLEE--------------QYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVA 1266

Query: 342  PQESWDEGDWTLSIPP---DMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385
            P+   D  D   S P    +   S Q   S+F+++EE+ VG +LD+G             
Sbjct: 1267 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1326

Query: 386  ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439
                  R    +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQ
Sbjct: 1327 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1386

Query: 440  PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499
            PYRS FY L++Q +G+A+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSL+R 
Sbjct: 1387 PYRSAFYVLEQQRVGMAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLNRC 1446

Query: 500  YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGE--EDQKPPCPRLNEV 557
            YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD I+K QE E  EDQ PPCPRL+  
Sbjct: 1447 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDEDQDPPCPRLSRE 1506

Query: 558  LMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
            L+E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE  V  +LDV
Sbjct: 1507 LLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDV 1558



 Score =  309 bits (792), Expect = 4e-84
 Identities = 187/406 (46%), Positives = 237/406 (58%), Gaps = 45/406 (11%)

Query: 233  EEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEE 289
            +E E+ Q    PR   E+   +  EV +DSL+ C  T S      +S QPY +     E+
Sbjct: 1094 KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQ 1153

Query: 290  DQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPRNLQESEEEEAPQESWDEG 349
             +V   +               + E E   E EE++ P  PR  +E  +E+ P+   D  
Sbjct: 1154 QRVGFAVD--------------MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL 1199

Query: 350  DWTLSIP------PDMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPR 403
            D   S P      PD+   Y S     +S+EEQ +GLALD+ R   D+ ++EDQ+   PR
Sbjct: 1200 DRCYSTPSGYLELPDLGQPYSS---AVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPR 1256

Query: 404  LSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMK 463
            LSRELL+   PEVLQDSLDR YSTP   LE PD CQPY S FY+L+E+H+G +LD+  ++
Sbjct: 1257 LSRELLEVVAPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIE 1316

Query: 464  KD-------------------QEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPF 504
            K                    +E EEDQ PPCPRLSREL +   PE LQDSLDR YSTP 
Sbjct: 1317 KKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPS 1376

Query: 505  SYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLMEAEEP 564
               EL DSCQPY S FY LE++ VG ++D+DEIEKYQE EEDQ P CPRL+  L++ +EP
Sbjct: 1377 GCLELTDSCQPYRSAFYVLEQQRVGMAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEP 1436

Query: 565  EVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDVD 610
            EVLQDSL+RCYST S Y +L    Q Y SA YS EEQ + LALDVD
Sbjct: 1437 EVLQDSLNRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 1482



 Score = 37.7 bits (86), Expect = 0.032
 Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 3/78 (3%)

Query: 533 DVDEIEKYQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYR 592
           D DE  + +E E+  +   PR    + +AEE +V +DSL+ C  T S       S Q ++
Sbjct: 169 DEDEDVQVEEAEKVLESSAPR---EVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHK 225

Query: 593 SAFYSFEEQDVSLALDVD 610
           +   +FEE +V+  L VD
Sbjct: 226 NIKITFEEDEVNSTLVVD 243


>gi|157266285 hypothetical protein LOC728936 [Homo sapiens]
          Length = 670

 Score =  818 bits (2114), Expect = 0.0
 Identities = 419/553 (75%), Positives = 466/553 (84%)

Query: 57  MVVSAGPWSGEKAEMNILEINKKSRPQLAENKQQFRNLKQKCLVTQVAYFLANRQNNYDY 116
           MVVSAGP S EKAEMNILEIN+K RPQLAE KQQFRNLK+KC +TQ+A FLANRQ  Y Y
Sbjct: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60

Query: 117 EDCKDLIKSMLRDERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQLREKLQEGRDAS 176
           E+CKDLIK MLR+ER   EEKLAE+L QAEELRQYKVLVH+QERELTQLREKL+EGRDAS
Sbjct: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120

Query: 177 RSLNQHLQALLTPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAE 236
           RSLN+HLQALLTPDEPD SQG+DL+EQLAEGCRL QHLVQKLSPEND+D+DEDV+VE AE
Sbjct: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180

Query: 237 KVQELYAPREVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTL 296
           KVQ+  APRE+QKAEEKEVPEDSLEECAITCSNSH P +SNQP+  T+ITFEED+VDSTL
Sbjct: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240

Query: 297 IDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPRNLQESEEEEAPQESWDEGDWTLSIP 356
           I SSSH EW DAV IIPENESD E+EEEKGPVSPRNLQESEEEE PQESWDEG  TLSIP
Sbjct: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 300

Query: 357 PDMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSRELLDEKEPEV 416
           P+M ASYQS  STFHS+EEQQV +A+DIGRH  DQVKKEDQEAT PRLSRELLDEKEPEV
Sbjct: 301 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 360

Query: 417 LQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPC 476
           LQDSLDR YSTP   LEL D CQPYRS FY L++Q +GLA+D+D ++K QE EEDQ P C
Sbjct: 361 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSC 420

Query: 477 PRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDE 536
           PRLSREL +  EPE LQDSLDR YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD 
Sbjct: 421 PRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDR 480

Query: 537 IEKYQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFY 596
           I+K QE EEDQ PPCPRL+  L+E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY
Sbjct: 481 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 540

Query: 597 SFEEQDVSLALDV 609
           + EE+ V  +LDV
Sbjct: 541 ALEEKHVGFSLDV 553


>gi|29789405 hypothetical protein LOC284565 [Homo sapiens]
          Length = 670

 Score =  815 bits (2106), Expect = 0.0
 Identities = 418/553 (75%), Positives = 465/553 (84%)

Query: 57  MVVSAGPWSGEKAEMNILEINKKSRPQLAENKQQFRNLKQKCLVTQVAYFLANRQNNYDY 116
           MVVSAGP S EKAEMNILEIN+K RPQLAE KQQFRNLK+KC +TQ+A FLANRQ  Y Y
Sbjct: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60

Query: 117 EDCKDLIKSMLRDERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQLREKLQEGRDAS 176
           E+CKDLIK MLR+ER   EEKLAE+L QAEELRQYKVLVH+QERELTQLREKL+EGRDAS
Sbjct: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120

Query: 177 RSLNQHLQALLTPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAE 236
           RSLN+HLQALLTPDEPD SQG+DL+EQLAEGCRL QHLVQKLSPEND+D+DEDV+VE AE
Sbjct: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180

Query: 237 KVQELYAPREVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTL 296
           KVQ+  APRE+QKAEEKEVPEDSLEECAITCSNSH P +SNQP+  T+ITFEED+VDSTL
Sbjct: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240

Query: 297 IDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPRNLQESEEEEAPQESWDEGDWTLSIP 356
           I SSSH EW DAV IIPENESD E+EEEKGPVSPRNLQESEEEE PQESWDEG  TLSIP
Sbjct: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 300

Query: 357 PDMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSRELLDEKEPEV 416
           P+M ASYQS  STFHS+EEQQV +A+DIGRH  DQVKKEDQEAT PRLSRELLDEKEPEV
Sbjct: 301 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 360

Query: 417 LQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPC 476
           LQDSLDR YSTP   LEL D CQPYRS FY L++Q +GLA+D+D ++K QE EEDQ P C
Sbjct: 361 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSC 420

Query: 477 PRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDE 536
           PRLSREL +  EPE LQDSLDR YSTP  Y ELPD  QPY S  YSLEE+++G +L VD 
Sbjct: 421 PRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDR 480

Query: 537 IEKYQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFY 596
           I+K QE EEDQ PPCPRL+  L+E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY
Sbjct: 481 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 540

Query: 597 SFEEQDVSLALDV 609
           + EE+ V  +LDV
Sbjct: 541 ALEEKHVGFSLDV 553


>gi|156071420 hypothetical protein LOC728912 [Homo sapiens]
          Length = 790

 Score =  806 bits (2082), Expect = 0.0
 Identities = 420/555 (75%), Positives = 461/555 (83%), Gaps = 1/555 (0%)

Query: 18  DVETSPFGAPRAASHGVGRHQELRDPTVPGPTSSATNVSMVVSAGPWSGEKAEMNILEIN 77
           D   S     R +SH  G    L    VPGPTSSATNVSMVVSAGP S EKAEMNILEIN
Sbjct: 159 DKVNSSLVVDRESSHD-GCQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEIN 217

Query: 78  KKSRPQLAENKQQFRNLKQKCLVTQVAYFLANRQNNYDYEDCKDLIKSMLRDERLLTEEK 137
           +K  PQLAE KQQFR+LK+KC VTQVA FLA +QN Y YE+CKDLIKSMLR+ER   EEK
Sbjct: 218 EKLCPQLAEKKQQFRSLKEKCFVTQVACFLAKQQNKYKYEECKDLIKSMLRNERQFKEEK 277

Query: 138 LAEELGQAEELRQYKVLVHSQERELTQLREKLQEGRDASRSLNQHLQALLTPDEPDNSQG 197
           LAE+L QAEELRQYKVLVHSQERELTQLREKL+EGRDASRSLN+HLQALLTPDEPD SQG
Sbjct: 278 LAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQG 337

Query: 198 RDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAEKVQELYAPREVQKAEEKEVPE 257
           +DL+EQLAEGCRLAQHLVQKLSPEND+D+DEDV+VE AEKVQ+  +PRE+QKAEEKEVPE
Sbjct: 338 QDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPREMQKAEEKEVPE 397

Query: 258 DSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENES 317
           DSLEECAITCSNSH P +SNQP+  T+ITFEED+VDSTLI SSSH EW DAV IIPENES
Sbjct: 398 DSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENES 457

Query: 318 DHEQEEEKGPVSPRNLQESEEEEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQ 377
           D E+EEEKGPVSPRNLQESEEEE PQESWDEG  TLSIPP+  ASYQS  STFHS+EEQQ
Sbjct: 458 DDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPERLASYQSYSSTFHSLEEQQ 517

Query: 378 VGLALDIGRHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDL 437
           V +A+DIGRH  DQVKKEDQEAT PRLSRELLDEKEPEVLQDSLDR YSTP  YL L D 
Sbjct: 518 VCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSVYLGLTDS 577

Query: 438 CQPYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLD 497
           CQPYRS FY L++Q +GLA+D+D ++K QE EEDQ P CPRLSREL    EPE LQDSLD
Sbjct: 578 CQPYRSAFYVLEQQRIGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDSLD 637

Query: 498 RWYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEV 557
           R YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD I+K QE EEDQ PPCPRL+  
Sbjct: 638 RCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRE 697

Query: 558 LMEAEEPEVLQDSLD 572
           L+E  EPEVLQDSLD
Sbjct: 698 LLEVVEPEVLQDSLD 712



 Score =  311 bits (798), Expect = 9e-85
 Identities = 218/520 (41%), Positives = 293/520 (56%), Gaps = 66/520 (12%)

Query: 146 EELRQYKVLVHSQERELTQLREKLQEGRDASRSLNQHLQALLTPDEPDNSQGRDLREQLA 205
           +E++QYKVLVHSQERELTQLREKL+EGRDASRSLN+HLQALLTPDEPD SQG+DL+EQLA
Sbjct: 15  QEIQQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 74

Query: 206 EGCRLAQHLVQKLSPENDDDEDEDVKVEEAEKVQELYAPREVQKAEEKEVPEDSLEECAI 265
           EGCRLAQHLVQKLSPEND+DEDEDV+VEE EKV E  APREVQKAEE +VPEDSLEECAI
Sbjct: 75  EGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESSAPREVQKAEESKVPEDSLEECAI 134

Query: 266 TCSNSHHPCESNQPYGNTRITFEEDQVDSTLI--DSSSHDEWLDAVCIIP-----ENESD 318
           TCSNSH PC+S QP+ N +ITFEED+V+S+L+    SSHD   DA+ I+P      + ++
Sbjct: 135 TCSNSHGPCDSIQPHKNIKITFEEDKVNSSLVVDRESSHDGCQDALNILPVPGPTSSATN 194

Query: 319 HEQEEEKGPVSPR----NLQESEEEEAPQ--------ESWDEGDWTLSIPPDMSASYQSD 366
                  GP+S      N+ E  E+  PQ         S  E  +   +   ++   Q +
Sbjct: 195 VSMVVSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVACFLAK--QQN 252

Query: 367 RSTFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQ-------- 418
           +  +   ++    +  +  +   +++ ++ ++A   R  + L+  +E E+ Q        
Sbjct: 253 KYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREG 312

Query: 419 DSLDRFYSTPFEYLELPDLCQPYRSDFYSLQE---------QHLGLALDLDRMKKDQEE- 468
               R  +   + L  PD  +P +S    LQE         QHL   L  +    D E+ 
Sbjct: 313 RDASRSLNEHLQALLTPD--EPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDV 370

Query: 469 -----EEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYSL 523
                E+ Q    P   RE+ +  E E  +DSL+    T  +     DS QP+     + 
Sbjct: 371 QVEVAEKVQKSSSP---REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITF 427

Query: 524 EEEHVGFSL--------------DVDEIEKYQEGEEDQKPPCPRLNEVLMEAEEPEVLQD 569
           EE+ V  +L               + E E   E EE++ P  PR    L E+EE EV Q+
Sbjct: 428 EEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQE 484

Query: 570 SLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
           S D  YST S   +  AS+Q Y S F+S EEQ V +A+D+
Sbjct: 485 SWDEGYSTLSIPPERLASYQSYSSTFHSLEEQQVCMAVDI 524



 Score = 38.5 bits (88), Expect = 0.019
 Identities = 37/132 (28%), Positives = 59/132 (44%), Gaps = 19/132 (14%)

Query: 479 LSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIE 538
           L+ + P+  + +DLQ+             +L + C+        L  E+     D DE E
Sbjct: 56  LTPDEPDKSQGQDLQE-------------QLAEGCRLAQHLVQKLSPEN-----DEDEDE 97

Query: 539 KYQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSF 598
             Q  EED+K         + +AEE +V +DSL+ C  T S       S Q +++   +F
Sbjct: 98  DVQV-EEDEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSIQPHKNIKITF 156

Query: 599 EEQDVSLALDVD 610
           EE  V+ +L VD
Sbjct: 157 EEDKVNSSLVVD 168


>gi|119709825 neuroblastoma breakpoint family, member 11-like [Homo
           sapiens]
          Length = 790

 Score =  806 bits (2082), Expect = 0.0
 Identities = 420/555 (75%), Positives = 461/555 (83%), Gaps = 1/555 (0%)

Query: 18  DVETSPFGAPRAASHGVGRHQELRDPTVPGPTSSATNVSMVVSAGPWSGEKAEMNILEIN 77
           D   S     R +SH  G    L    VPGPTSSATNVSMVVSAGP S EKAEMNILEIN
Sbjct: 159 DKVNSSLVVDRESSHD-GCQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEIN 217

Query: 78  KKSRPQLAENKQQFRNLKQKCLVTQVAYFLANRQNNYDYEDCKDLIKSMLRDERLLTEEK 137
           +K  PQLAE KQQFR+LK+KC VTQVA FLA +QN Y YE+CKDLIKSMLR+ER   EEK
Sbjct: 218 EKLCPQLAEKKQQFRSLKEKCFVTQVACFLAKQQNKYKYEECKDLIKSMLRNERQFKEEK 277

Query: 138 LAEELGQAEELRQYKVLVHSQERELTQLREKLQEGRDASRSLNQHLQALLTPDEPDNSQG 197
           LAE+L QAEELRQYKVLVHSQERELTQLREKL+EGRDASRSLN+HLQALLTPDEPD SQG
Sbjct: 278 LAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQG 337

Query: 198 RDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAEKVQELYAPREVQKAEEKEVPE 257
           +DL+EQLAEGCRLAQHLVQKLSPEND+D+DEDV+VE AEKVQ+  +PRE+QKAEEKEVPE
Sbjct: 338 QDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPREMQKAEEKEVPE 397

Query: 258 DSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENES 317
           DSLEECAITCSNSH P +SNQP+  T+ITFEED+VDSTLI SSSH EW DAV IIPENES
Sbjct: 398 DSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENES 457

Query: 318 DHEQEEEKGPVSPRNLQESEEEEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQ 377
           D E+EEEKGPVSPRNLQESEEEE PQESWDEG  TLSIPP+  ASYQS  STFHS+EEQQ
Sbjct: 458 DDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPERLASYQSYSSTFHSLEEQQ 517

Query: 378 VGLALDIGRHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDL 437
           V +A+DIGRH  DQVKKEDQEAT PRLSRELLDEKEPEVLQDSLDR YSTP  YL L D 
Sbjct: 518 VCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSVYLGLTDS 577

Query: 438 CQPYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLD 497
           CQPYRS FY L++Q +GLA+D+D ++K QE EEDQ P CPRLSREL    EPE LQDSLD
Sbjct: 578 CQPYRSAFYVLEQQRIGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDSLD 637

Query: 498 RWYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEV 557
           R YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD I+K QE EEDQ PPCPRL+  
Sbjct: 638 RCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRE 697

Query: 558 LMEAEEPEVLQDSLD 572
           L+E  EPEVLQDSLD
Sbjct: 698 LLEVVEPEVLQDSLD 712



 Score =  313 bits (801), Expect = 4e-85
 Identities = 219/520 (42%), Positives = 293/520 (56%), Gaps = 66/520 (12%)

Query: 146 EELRQYKVLVHSQERELTQLREKLQEGRDASRSLNQHLQALLTPDEPDNSQGRDLREQLA 205
           EE++QYKVLVHSQERELTQLREKL+EGRDASRSLN+HLQALLTPDEPD SQG+DL+EQLA
Sbjct: 15  EEIQQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 74

Query: 206 EGCRLAQHLVQKLSPENDDDEDEDVKVEEAEKVQELYAPREVQKAEEKEVPEDSLEECAI 265
           EGCRLAQHLVQKLSPEND+DEDEDV+VEE EKV E  APREVQKAEE +VPEDSLEECAI
Sbjct: 75  EGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESSAPREVQKAEESKVPEDSLEECAI 134

Query: 266 TCSNSHHPCESNQPYGNTRITFEEDQVDSTLI--DSSSHDEWLDAVCIIP-----ENESD 318
           TCSNSH PC+S QP+ N +ITFEED+V+S+L+    SSHD   DA+ I+P      + ++
Sbjct: 135 TCSNSHGPCDSIQPHKNIKITFEEDKVNSSLVVDRESSHDGCQDALNILPVPGPTSSATN 194

Query: 319 HEQEEEKGPVSPR----NLQESEEEEAPQ--------ESWDEGDWTLSIPPDMSASYQSD 366
                  GP+S      N+ E  E+  PQ         S  E  +   +   ++   Q +
Sbjct: 195 VSMVVSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVACFLAK--QQN 252

Query: 367 RSTFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQ-------- 418
           +  +   ++    +  +  +   +++ ++ ++A   R  + L+  +E E+ Q        
Sbjct: 253 KYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREG 312

Query: 419 DSLDRFYSTPFEYLELPDLCQPYRSDFYSLQE---------QHLGLALDLDRMKKDQEE- 468
               R  +   + L  PD  +P +S    LQE         QHL   L  +    D E+ 
Sbjct: 313 RDASRSLNEHLQALLTPD--EPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDV 370

Query: 469 -----EEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYSL 523
                E+ Q    P   RE+ +  E E  +DSL+    T  +     DS QP+     + 
Sbjct: 371 QVEVAEKVQKSSSP---REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITF 427

Query: 524 EEEHVGFSL--------------DVDEIEKYQEGEEDQKPPCPRLNEVLMEAEEPEVLQD 569
           EE+ V  +L               + E E   E EE++ P  PR    L E+EE EV Q+
Sbjct: 428 EEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQE 484

Query: 570 SLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
           S D  YST S   +  AS+Q Y S F+S EEQ V +A+D+
Sbjct: 485 SWDEGYSTLSIPPERLASYQSYSSTFHSLEEQQVCMAVDI 524



 Score = 38.5 bits (88), Expect = 0.019
 Identities = 37/132 (28%), Positives = 59/132 (44%), Gaps = 19/132 (14%)

Query: 479 LSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIE 538
           L+ + P+  + +DLQ+             +L + C+        L  E+     D DE E
Sbjct: 56  LTPDEPDKSQGQDLQE-------------QLAEGCRLAQHLVQKLSPEN-----DEDEDE 97

Query: 539 KYQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSF 598
             Q  EED+K         + +AEE +V +DSL+ C  T S       S Q +++   +F
Sbjct: 98  DVQV-EEDEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSIQPHKNIKITF 156

Query: 599 EEQDVSLALDVD 610
           EE  V+ +L VD
Sbjct: 157 EEDKVNSSLVVD 168


>gi|7657017 hypothetical protein LOC25832 [Homo sapiens]
          Length = 921

 Score =  703 bits (1815), Expect = 0.0
 Identities = 361/484 (74%), Positives = 405/484 (83%)

Query: 126 MLRDERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQLREKLQEGRDASRSLNQHLQA 185
           MLR+ER   EEKLAE+L QAEELRQYKVLVH+QERELTQLREKL+EGRDASRSLN+HLQA
Sbjct: 1   MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 60

Query: 186 LLTPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAEKVQELYAPR 245
           LLTPDEPD SQG+DL+EQLAEGCRLAQHLVQKLSPEND+D+DEDV+VE AEKVQ+  APR
Sbjct: 61  LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 120

Query: 246 EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTLIDSSSHDEW 305
           E+QKAEEKEVPEDSLEECAITCSNSH P +SNQP+  T+ITFEED+VDSTLI SSSH EW
Sbjct: 121 EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW 180

Query: 306 LDAVCIIPENESDHEQEEEKGPVSPRNLQESEEEEAPQESWDEGDWTLSIPPDMSASYQS 365
            DAV IIPENESD E+EEEKGPVSPRNLQESEEEE PQESWDEG  TLSIPP+M ASY+S
Sbjct: 181 EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYKS 240

Query: 366 DRSTFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFY 425
             STFHS+EEQQV +A+DIGRH  DQVKKED EAT PRLSRELLDEK PEVLQDSLDR Y
Sbjct: 241 YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCY 300

Query: 426 STPFEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPE 485
           STP   LEL D CQPYRS FY L++Q +GLA+++D ++K QE EEDQ P CPRLSREL +
Sbjct: 301 STPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLD 360

Query: 486 VVEPEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEE 545
             EPE LQDSL R YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD I+K QE EE
Sbjct: 361 EKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE 420

Query: 546 DQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSL 605
           DQ PPCPRL+  L+E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE+ V  
Sbjct: 421 DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 480

Query: 606 ALDV 609
           +LDV
Sbjct: 481 SLDV 484



 Score =  408 bits (1048), Expect = e-114
 Identities = 239/425 (56%), Positives = 278/425 (65%), Gaps = 39/425 (9%)

Query: 233 EEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEE 289
           +E E+ Q    PR   E+   +  EV +DSL+ C  T S      +S QPY +     E+
Sbjct: 510 KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQ 569

Query: 290 DQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEEEEAPQESW 346
            +V    +D             + E E   E EE++ P  PR    L + +E E  QES 
Sbjct: 570 QRV-GLAVD-------------MDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQESL 615

Query: 347 DEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSR 406
           D    T S   +++ S Q  RS F+ +E+Q+VGLA+D+      Q  +EDQ+ + PRLSR
Sbjct: 616 DRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSR 675

Query: 407 ELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMKKDQ 466
           ELLDEKEPEVLQDSL R YSTP  YLELPDL QPY S  YSL+EQ+LGLALD+DR+KKDQ
Sbjct: 676 ELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQ 735

Query: 467 EEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLEEE 526
           EEEEDQGPPCPRLSREL EVVEPE LQDSLDR YSTP S  E PDSCQPYGS FY+LEE+
Sbjct: 736 EEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEK 795

Query: 527 HVGFSLDVDEIEK-------------------YQEGEEDQKPPCPRLNEVLMEAEEPEVL 567
           HVGFSLDV EIEK                    +EGEEDQ PPCPRLN +LME EEPEVL
Sbjct: 796 HVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSMLMEVEEPEVL 855

Query: 568 QDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDVDNRFFTLTVIRHHLAFQM 627
           QDSLD CYST S YF+L  SFQ YRS FYSFEE+ +S AL VDNRFFTLTV   HL FQM
Sbjct: 856 QDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSLHLVFQM 915

Query: 628 GVIFP 632
           GVIFP
Sbjct: 916 GVIFP 920



 Score =  365 bits (937), Expect = e-101
 Identities = 216/410 (52%), Positives = 265/410 (64%), Gaps = 37/410 (9%)

Query: 220 PENDDDEDEDVKVEEAEKVQELYAPREVQKAEEKEVPEDSLEECAITCSNSHHPCESNQP 279
           PEN+ D++E+   EE   V    +PR +Q++EE+EVP++S +E   T S       S + 
Sbjct: 188 PENESDDEEE---EEKGPV----SPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYKS 240

Query: 280 YGNTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPRNLQESEEE 339
           Y +T  + EE QV    +D   H  W         ++   E  E  GP   R L + +  
Sbjct: 241 YSSTFHSLEEQQV-CMAVDIGRH-RW---------DQVKKEDHEATGPRLSRELLDEKGP 289

Query: 340 EAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVKKEDQEA 399
           E  Q+S D    T S   +++ S Q  RS F+ +E+Q+VGLA+++      Q  +EDQ+ 
Sbjct: 290 EVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDP 349

Query: 400 TSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHLGLALDL 459
           + PRLSRELLDEKEPEVLQDSL R YSTP  YLELPDL QPY S  YSL+EQ+LGLALD+
Sbjct: 350 SCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDV 409

Query: 460 DRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSCQPYGSC 519
           DR+KKDQEEEEDQGPPCPRLSREL EVVEPE LQDSLDR YSTP S  E PDSCQPYGS 
Sbjct: 410 DRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSS 469

Query: 520 FYSLEEEHVGFSLDVDEIEK-------------------YQEGEEDQKPPCPRLNEVLME 560
           FY+LEE+HVGFSLDV EIEK                    +EGEEDQ PPCPRL+  L++
Sbjct: 470 FYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLD 529

Query: 561 AEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDVD 610
            + PEVLQDSLDRCYST S   +L  S Q YRSAFY  E+Q V LA+D+D
Sbjct: 530 EKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMD 579



 Score =  322 bits (825), Expect = 7e-88
 Identities = 192/396 (48%), Positives = 247/396 (62%), Gaps = 11/396 (2%)

Query: 225 DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
           D D   K +E E+ Q    PR   E+ +  E EV +DSL+ C  T S+     +S QPYG
Sbjct: 408 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 467

Query: 282 NTRITFEEDQVDSTL----IDSSSHDEWLDAVCIIPENESDHEQ-EEEKGPVSPRNLQES 336
           ++    EE  V  +L    I+     +         E     ++ EE++ P  PR  +E 
Sbjct: 468 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 527

Query: 337 EEEEAPQESWDEGDWTLSIPP---DMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVK 393
            +E+ P+   D  D   S P    +++ S Q  RS F+ +E+Q+VGLA+D+      Q  
Sbjct: 528 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEV 587

Query: 394 KEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHL 453
           +EDQ+ + PRLS ELLDEKEPEVLQ+SLDR YSTP   LEL D CQPYRS FY L++Q +
Sbjct: 588 EEDQDPSCPRLSGELLDEKEPEVLQESLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRV 647

Query: 454 GLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSC 513
           GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSL R YSTP  Y ELPD  
Sbjct: 648 GLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLG 707

Query: 514 QPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDR 573
           QPY S  YSLEE+++G +LDVD I+K QE EEDQ PPCPRL+  L+E  EPEVLQDSLDR
Sbjct: 708 QPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDR 767

Query: 574 CYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
           CYST S+  +   S Q Y S+FY+ EE+ V  +LDV
Sbjct: 768 CYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 803



 Score =  318 bits (816), Expect = 7e-87
 Identities = 194/409 (47%), Positives = 241/409 (58%), Gaps = 39/409 (9%)

Query: 227 DEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNT 283
           DE  K +E E+ Q+   PR   E+   +E EV +DSL  C  T S      +  QPY + 
Sbjct: 335 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSA 394

Query: 284 RITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEEEE 340
             + EE              ++L     +   + D E+EE++GP  PR    L E  E E
Sbjct: 395 VYSLEE--------------QYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPE 440

Query: 341 APQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG--------------- 385
             Q+S D    T S   +   S Q   S+F+++EE+ VG +LD+G               
Sbjct: 441 VLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR 500

Query: 386 ----RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPY 441
               R    +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQPY
Sbjct: 501 SKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPY 560

Query: 442 RSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYS 501
           RS FY L++Q +GLA+D+D ++K QE EEDQ P CPRLS EL +  EPE LQ+SLDR YS
Sbjct: 561 RSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQESLDRCYS 620

Query: 502 TPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLMEA 561
           TP    EL DSCQPY S FY LE++ VG ++D+DEIEKYQE EEDQ P CPRL+  L++ 
Sbjct: 621 TPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDE 680

Query: 562 EEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDVD 610
           +EPEVLQDSL RCYST S Y +L    Q Y SA YS EEQ + LALDVD
Sbjct: 681 KEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 729



 Score =  124 bits (310), Expect = 3e-28
 Identities = 92/261 (35%), Positives = 127/261 (48%), Gaps = 39/261 (14%)

Query: 225 DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281
           D DE  K +E E+ Q+   PR   E+   +E EV +DSL  C  T S      +  QPY 
Sbjct: 652 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYS 711

Query: 282 NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSP---RNLQESEE 338
           +   + EE              ++L     +   + D E+EE++GP  P   R L E  E
Sbjct: 712 SAVYSLEE--------------QYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 757

Query: 339 EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385
            E  Q+S D    T S   +   S Q   S+F+++EE+ VG +LD+G             
Sbjct: 758 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 817

Query: 386 ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439
                 R    +  +EDQ    PRL+  L++ +EPEVLQDSLD  YSTP  Y ELPD  Q
Sbjct: 818 RRSKKERRRGRKEGEEDQNPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQ 877

Query: 440 PYRSDFYSLQEQHLGLALDLD 460
            YRS FYS +E+H+  AL +D
Sbjct: 878 HYRSVFYSFEEEHISFALYVD 898


>gi|221136844 neuroblastoma breakpoint family, member 6 isoform 1
           [Homo sapiens]
          Length = 667

 Score =  467 bits (1202), Expect = e-131
 Identities = 275/508 (54%), Positives = 345/508 (67%), Gaps = 36/508 (7%)

Query: 57  MVVSAGPWSGEKAEMNILEINKKSRPQLAENKQQFRNLKQKCLVTQV-AYFLANRQNNYD 115
           MVVSA P S E+AEMNILEIN++ R QLAE+ QQFR+LK+K L+TQ  AY LAN+   Y 
Sbjct: 1   MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60

Query: 116 YEDCKDLIKSMLRDERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQLREKLQEGRDA 175
            E+ KD+I S+LRDE L + EKLAE+L QAEELRQYK LVHSQ +ELTQLREKL+EGRDA
Sbjct: 61  CEEYKDIIDSVLRDE-LQSMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119

Query: 176 SRSLNQHLQALLTPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDV--KVE 233
           SR LN+HL+ LLTPD+PD SQG+DLREQLAEG RLA+HLV KLSPEND+DEDED   K E
Sbjct: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179

Query: 234 EAEKVQELYAPREVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVD 293
           E EKVQE  APREVQK EEKEVP+DSLEECA+TCSNSH+P  SNQP+ +T+ITF+E +VD
Sbjct: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239

Query: 294 STLIDSSS--HDEWLDAVCIIPENESDHEQEEEKGPVSPRNLQESEEEEAPQESWDEGDW 351
           S L+  S   HDE  +A+ I PEN++DHE+EE K PV PRN Q  E    P E  +  D+
Sbjct: 240 SALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRNRQSLE----PGELTNLRDF 295

Query: 352 TLSI---------PPDMSASYQSDRSTFHSVEEQQVGLALDIGRHW-------------- 388
            +S            D S SY+    +F +++EQ+V  A D+ R +              
Sbjct: 296 LISPVVSHVANPGHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLE 355

Query: 389 --CDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFY 446
              D  + + QE  +PRLSR  L   + E+ Q+SLD    TP    +L     PY S  Y
Sbjct: 356 KQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLY 415

Query: 447 SLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSY 506
           S +++ + LAL +D++KKDQEE EDQ PPCPRLS+ELPEV E E  +DS++  Y TP  +
Sbjct: 416 SFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVH 474

Query: 507 PELPDSCQPYGSCFYSLEEEHVGFSLDV 534
            ++ D  QPY S   SLE++    +LDV
Sbjct: 475 HDVSDCHQPYSSTLSSLEDQLACSALDV 502



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 31/79 (39%), Positives = 44/79 (55%), Gaps = 3/79 (3%)

Query: 533 DVDEIEKYQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYR 592
           D DE +K +E E+ Q+ P PR    + + EE EV QDSL+ C  T S       S Q +R
Sbjct: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 593 SAFYSFEEQDVSLALDVDN 611
           S   +F+E +V  AL V++
Sbjct: 228 STKITFKEHEVDSALVVES 246


>gi|221136848 neuroblastoma breakpoint family, member 6 isoform 2
           [Homo sapiens]
          Length = 638

 Score =  459 bits (1182), Expect = e-129
 Identities = 268/499 (53%), Positives = 336/499 (67%), Gaps = 47/499 (9%)

Query: 57  MVVSAGPWSGEKAEMNILEINKKSRPQLAENKQQFRNLKQKCLVTQV-AYFLANRQNNYD 115
           MVVSA P S E+AEMNILEIN++ R QLAE+ QQFR+LK+K L+TQ  AY LAN+   Y 
Sbjct: 1   MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60

Query: 116 YEDCKDLIKSMLRDERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQLREKLQEGRDA 175
            E+ KD+I S+LRDE L + EKLAE+L QAEELRQYK LVHSQ +ELTQLREKL+EGRDA
Sbjct: 61  CEEYKDIIDSVLRDE-LQSMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119

Query: 176 SRSLNQHLQALLTPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDV--KVE 233
           SR LN+HL+ LLTPD+PD SQG+DLREQLAEG RLA+HLV KLSPEND+DEDED   K E
Sbjct: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179

Query: 234 EAEKVQELYAPREVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVD 293
           E EKVQE  APREVQK EEKEVP+DSLEECA+TCSNSH+P  SNQP+ +T+ITF+E +VD
Sbjct: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239

Query: 294 STLIDSSS--HDEWLDAVCIIPENESDHEQEEEKGPVSPRNLQESEEEEAPQESWDEGDW 351
           S L+  S   HDE  +A+ I PEN++DHE+EE K PV PR+                   
Sbjct: 240 SALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRH------------------- 280

Query: 352 TLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIGRHW----------------CDQVKKE 395
                 D S SY+    +F +++EQ+V  A D+ R +                 D  + +
Sbjct: 281 -----HDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVK 335

Query: 396 DQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHLGL 455
            QE  +PRLSR  L   + E+ Q+SLD    TP    +L     PY S  YS +++ + L
Sbjct: 336 GQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSL 395

Query: 456 ALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSCQP 515
           AL +D++KKDQEE EDQ PPCPRLS+ELPEV E E  +DS++  Y TP  + ++ D  QP
Sbjct: 396 AL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQP 454

Query: 516 YGSCFYSLEEEHVGFSLDV 534
           Y S   SLE++    +LDV
Sbjct: 455 YSSTLSSLEDQLACSALDV 473



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 31/79 (39%), Positives = 44/79 (55%), Gaps = 3/79 (3%)

Query: 533 DVDEIEKYQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYR 592
           D DE +K +E E+ Q+ P PR    + + EE EV QDSL+ C  T S       S Q +R
Sbjct: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 593 SAFYSFEEQDVSLALDVDN 611
           S   +F+E +V  AL V++
Sbjct: 228 STKITFKEHEVDSALVVES 246


>gi|221218991 neuroblastoma breakpoint family, member 4 [Homo
           sapiens]
          Length = 638

 Score =  459 bits (1182), Expect = e-129
 Identities = 268/499 (53%), Positives = 336/499 (67%), Gaps = 47/499 (9%)

Query: 57  MVVSAGPWSGEKAEMNILEINKKSRPQLAENKQQFRNLKQKCLVTQV-AYFLANRQNNYD 115
           MVVSA P S E+AEMNILEIN++ R QLAE+ QQFR+LK+K L+TQ  AY LAN+   Y 
Sbjct: 1   MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60

Query: 116 YEDCKDLIKSMLRDERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQLREKLQEGRDA 175
            E+ KD+I S+LRDE L + EKLAE+L QAEELRQYK LVHSQ +ELTQLREKL+EGRDA
Sbjct: 61  CEEYKDIIDSVLRDE-LQSMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119

Query: 176 SRSLNQHLQALLTPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDV--KVE 233
           SR LN+HL+ LLTPD+PD SQG+DLREQLAEG RLA+HLV KLSPEND+DEDED   K E
Sbjct: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179

Query: 234 EAEKVQELYAPREVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVD 293
           E EKVQE  APREVQK EEKEVP+DSLEECA+TCSNSH+P  SNQP+ +T+ITF+E +VD
Sbjct: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239

Query: 294 STLIDSSS--HDEWLDAVCIIPENESDHEQEEEKGPVSPRNLQESEEEEAPQESWDEGDW 351
           S L+  S   HDE  +A+ I PEN++DHE+EE K PV PR+                   
Sbjct: 240 SALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRH------------------- 280

Query: 352 TLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIGRHW----------------CDQVKKE 395
                 D S SY+    +F +++EQ+V  A D+ R +                 D  + +
Sbjct: 281 -----HDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVK 335

Query: 396 DQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHLGL 455
            QE  +PRLSR  L   + E+ Q+SLD    TP    +L     PY S  YS +++ + L
Sbjct: 336 GQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSL 395

Query: 456 ALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSCQP 515
           AL +D++KKDQEE EDQ PPCPRLS+ELPEV E E  +DS++  Y TP  + ++ D  QP
Sbjct: 396 AL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQP 454

Query: 516 YGSCFYSLEEEHVGFSLDV 534
           Y S   SLE++    +LDV
Sbjct: 455 YSSTLSSLEDQLACSALDV 473



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 31/79 (39%), Positives = 44/79 (55%), Gaps = 3/79 (3%)

Query: 533 DVDEIEKYQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYR 592
           D DE +K +E E+ Q+ P PR    + + EE EV QDSL+ C  T S       S Q +R
Sbjct: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 593 SAFYSFEEQDVSLALDVDN 611
           S   +F+E +V  AL V++
Sbjct: 228 STKITFKEHEVDSALVVES 246


>gi|114158664 hypothetical protein LOC343505 [Homo sapiens]
          Length = 421

 Score =  449 bits (1156), Expect = e-126
 Identities = 248/384 (64%), Positives = 287/384 (74%), Gaps = 11/384 (2%)

Query: 45  VPGPTSSATNVSMVVSAGPWSGEKAEMNILEINKKSRPQLAENKQQFRNLKQKCLVTQVA 104
           VPG TSSATNV+MVVSAGPWS EKAEMNILEIN+K RPQLAENKQQFRN+KQK LVTQ+A
Sbjct: 9   VPGSTSSATNVTMVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMA 68

Query: 105 YFLANRQNNYDYEDCKDLIKSMLRDERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQ 164
            FLAN+QN Y YE+CKDLIKSMLR+E    EEKLAE+L QAEELRQYKVLVHSQEREL Q
Sbjct: 69  GFLANQQNKYKYEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQ 128

Query: 165 LREKLQEGRDASRSLNQHLQALLTPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDD 224
           LREKL+EGRDAS SLNQHLQALLTPD+ DNSQG+D REQLAEGCRLA+HLV KLSPEND 
Sbjct: 129 LREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDT 188

Query: 225 DEDEDVKVEEAEKVQELYAPREVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTR 284
           DEDE+ K +E +KVQE  APRE QKAEEKEVPEDSLEECAIT SNSH P +SN P+ N +
Sbjct: 189 DEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIK 248

Query: 285 ITFEEDQVDSTLI--DSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR--------NLQ 334
           IT EED+V+S L+    SS DEW DA+ I+ EN++D E+EE K PV P+         LQ
Sbjct: 249 ITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQ 308

Query: 335 ESEEEEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVKK 394
           ESEE+E  Q+S +E   T     D+S SYQ    TF ++ EQ+V  A D+     +  K 
Sbjct: 309 ESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNS-KG 367

Query: 395 EDQEATSPRLSRELLDEKEPEVLQ 418
           E+     P       DEK+  + Q
Sbjct: 368 EETPLGFPDTKYCWKDEKDERMSQ 391



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 49/173 (28%), Positives = 72/173 (41%), Gaps = 24/173 (13%)

Query: 458 DLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSCQPYG 517
           D D   K +E ++ Q  P PR  ++  E   PED  +     YS         DS  P+ 
Sbjct: 189 DEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPS---DSNPPHK 245

Query: 518 SCFYSLEEEHVGFSLDVDE--------------IEKYQEGEEDQ-KPPCPRLNEV----- 557
           +   + EE+ V   L VD               +E   + EE++ K P P    +     
Sbjct: 246 NIKITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGL 305

Query: 558 -LMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609
            L E+EE EVLQDS +   +T+ +   +  S+Q     F +  EQ V  A DV
Sbjct: 306 KLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDV 358



 Score = 39.7 bits (91), Expect = 0.009
 Identities = 31/104 (29%), Positives = 51/104 (49%), Gaps = 6/104 (5%)

Query: 508 ELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLMEAEEPEVL 567
           +L + C+      + L  E+     D DE +K +E ++ Q+ P PR  +   +AEE EV 
Sbjct: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQ---KAEEKEVP 220

Query: 568 QDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDVDN 611
           +DSL+ C  T S       S   +++   + EE  V+  L VD+
Sbjct: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDS 264


>gi|239741297 PREDICTED: neuroblastoma breakpoint family, member 9
           [Homo sapiens]
          Length = 299

 Score =  448 bits (1152), Expect = e-126
 Identities = 228/287 (79%), Positives = 253/287 (88%)

Query: 57  MVVSAGPWSGEKAEMNILEINKKSRPQLAENKQQFRNLKQKCLVTQVAYFLANRQNNYDY 116
           MVVSAGP S EKAEMNILEIN+K RPQLAE KQQFR+LK+KC VTQ+A FLA +QN Y Y
Sbjct: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKY 60

Query: 117 EDCKDLIKSMLRDERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQLREKLQEGRDAS 176
           E+CKDLIKSMLR+E    EEKLAE+L QAEELRQYKVLVHSQERELTQLREKL+EGRDAS
Sbjct: 61  EECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120

Query: 177 RSLNQHLQALLTPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAE 236
           RSLN+HLQALLTPDEPD SQG+DL+EQLAEGCRLAQHLVQKLSPEND+D+DEDV+VE AE
Sbjct: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 180

Query: 237 KVQELYAPREVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTL 296
           KVQ+  +PRE+QKAEEKEVPEDSLEECAITCSNSH P +SNQP+  T+ITFEED+VDSTL
Sbjct: 181 KVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240

Query: 297 IDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPRNLQESEEEEAPQ 343
           I SSSH EW DAV IIPENESD E+EEEKGPVSPR    S E+  P+
Sbjct: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTSVGSSEKGGPR 287



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 27/75 (36%), Positives = 37/75 (49%), Gaps = 3/75 (4%)

Query: 533 DVDEIEKYQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYR 592
           D DE  + +  E+ QK   PR    + +AEE EV +DSL+ C  T S     + S Q +R
Sbjct: 169 DDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 225

Query: 593 SAFYSFEEQDVSLAL 607
               +FEE  V   L
Sbjct: 226 KTKITFEEDKVDSTL 240



 Score = 34.3 bits (77), Expect = 0.36
 Identities = 29/104 (27%), Positives = 47/104 (45%), Gaps = 17/104 (16%)

Query: 391 QVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQE 450
           +V ++ Q+++SPR   E+   +E EV +DSL+    T        D  QP+R    + +E
Sbjct: 177 EVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEE 233

Query: 451 QHLGLALD--------------LDRMKKDQEEEEDQGPPCPRLS 480
             +   L               +   + D EEEE++GP  PR S
Sbjct: 234 DKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTS 277


>gi|239758011 PREDICTED: hypothetical protein LOC728841, partial
           [Homo sapiens]
          Length = 166

 Score =  160 bits (405), Expect = 3e-39
 Identities = 84/143 (58%), Positives = 97/143 (67%), Gaps = 19/143 (13%)

Query: 508 ELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKY-------------------QEGEEDQK 548
           E PDSCQPYGS FY+LEE+HVGFSLDV EIEK                    +EGEEDQ 
Sbjct: 2   EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQN 61

Query: 549 PPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALD 608
           PPCPRL+  L++ +EPEVLQDSLDRCYST S Y +L    Q Y SA YS EEQ + LALD
Sbjct: 62  PPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD 121

Query: 609 VDNRFFTLTVIRHHLAFQMGVIF 631
           VD+ + T+ VI  HL FQ+GVIF
Sbjct: 122 VDSEYLTMKVISLHLVFQIGVIF 144



 Score =  127 bits (320), Expect = 2e-29
 Identities = 66/123 (53%), Positives = 80/123 (65%), Gaps = 19/123 (15%)

Query: 432 LELPDLCQPYRSDFYSLQEQHLGLALDLDRMKKD-------------------QEEEEDQ 472
           LE PD CQPY S FY+L+E+H+G +LD+  ++K                    +E EEDQ
Sbjct: 1   LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 473 GPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSL 532
            PPCPRLSREL +  EPE LQDSLDR YSTP  Y ELPD  QPY S  YSLEE+++G +L
Sbjct: 61  NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 533 DVD 535
           DVD
Sbjct: 121 DVD 123



 Score =  111 bits (278), Expect = 2e-24
 Identities = 64/118 (54%), Positives = 76/118 (64%), Gaps = 19/118 (16%)

Query: 362 SYQSDRSTFHSVEEQQVGLALDIG-------------------RHWCDQVKKEDQEATSP 402
           S Q   S+F+++EE+ VG +LD+G                   R    +  +EDQ    P
Sbjct: 6   SCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQNPPCP 65

Query: 403 RLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHLGLALDLD 460
           RLSRELLDEKEPEVLQDSLDR YSTP  YLELPDL QPY S  YSL+EQ+LGLALD+D
Sbjct: 66  RLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 123



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 26/71 (36%), Positives = 37/71 (52%), Gaps = 9/71 (12%)

Query: 320 EQEEEKGPVSPRNLQESEEEEAPQESWDEGDWTLSIP------PDMSASYQSDRSTFHSV 373
           E EE++ P  PR  +E  +E+ P+   D  D   S P      PD+   Y    S  +S+
Sbjct: 55  EGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS---SAVYSL 111

Query: 374 EEQQVGLALDI 384
           EEQ +GLALD+
Sbjct: 112 EEQYLGLALDV 122



 Score = 30.0 bits (66), Expect = 6.8
 Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 4/71 (5%)

Query: 233 EEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEE 289
           +E E+ Q    PR   E+   +E EV +DSL+ C  T S      +  QPY +   + EE
Sbjct: 54  KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 113

Query: 290 DQVDSTL-IDS 299
             +   L +DS
Sbjct: 114 QYLGLALDVDS 124


>gi|239747446 PREDICTED: similar to Neuroblastoma breakpoint family
           member 6-like protein [Homo sapiens]
          Length = 298

 Score =  107 bits (266), Expect = 4e-23
 Identities = 68/181 (37%), Positives = 101/181 (55%), Gaps = 8/181 (4%)

Query: 57  MVVSAGPWSGEKAEMNILEINKKSRPQLAENKQQFRNLKQKCLVTQV-AYFLANRQNNYD 115
           M VSA    G +AEM+ILE N+  R +L + KQ F++L +K L ++  AY L N    Y 
Sbjct: 1   MAVSATTCFGPRAEMSILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60

Query: 116 YEDCKDLIKSMLRDERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQLREKLQEGRDA 175
            E+CKDLI+S+L +E    E +LAE    A  LR +  L+ +Q  ELT LR+K+QEGR  
Sbjct: 61  CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKIQEGRGV 120

Query: 176 SRSLNQHL-------QALLTPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDDDEDE 228
                QH+       + LL   +    Q +   EQ+ +G +L + LV+KL+ EN + +  
Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTDIAYYQRQRFCEQMVQGSQLTEILVRKLATENHNGKKN 180

Query: 229 D 229
           +
Sbjct: 181 E 181


>gi|239741304 PREDICTED: similar to Neuroblastoma breakpoint family
           member 6-like protein [Homo sapiens]
          Length = 298

 Score =  104 bits (259), Expect = 3e-22
 Identities = 67/181 (37%), Positives = 100/181 (55%), Gaps = 8/181 (4%)

Query: 57  MVVSAGPWSGEKAEMNILEINKKSRPQLAENKQQFRNLKQKCLVTQV-AYFLANRQNNYD 115
           M VSA    G +AE++ILE N+  R +L + KQ F++L +K L ++  AY L N    Y 
Sbjct: 1   MAVSATTCFGPRAEISILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60

Query: 116 YEDCKDLIKSMLRDERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQLREKLQEGRDA 175
            E+CKDLI+S+L +E    E +LAE    A  LR +  L+ +Q  ELT LR+K QEGR  
Sbjct: 61  CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKTQEGRGV 120

Query: 176 SRSLNQHL-------QALLTPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDDDEDE 228
                QH+       + LL   +    Q +   EQ+ +G +L + LV+KL+ EN + +  
Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTDIAYYQRQRFCEQMVQGSQLTEILVRKLATENHNGKKN 180

Query: 229 D 229
           +
Sbjct: 181 E 181


>gi|239741281 PREDICTED: Neuroblastoma breakpoint family member
           6-like protein [Homo sapiens]
          Length = 322

 Score =  104 bits (259), Expect = 3e-22
 Identities = 67/181 (37%), Positives = 100/181 (55%), Gaps = 8/181 (4%)

Query: 57  MVVSAGPWSGEKAEMNILEINKKSRPQLAENKQQFRNLKQKCLVTQV-AYFLANRQNNYD 115
           M VSA    G +AE++ILE N+  R +L + KQ F++L +K L ++  AY L N    Y 
Sbjct: 1   MAVSATTCFGPRAEISILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60

Query: 116 YEDCKDLIKSMLRDERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQLREKLQEGRDA 175
            E+CKDLI+S+L +E    E +LAE    A  LR +  L+ +Q  ELT LR+K QEGR  
Sbjct: 61  CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKTQEGRGV 120

Query: 176 SRSLNQHL-------QALLTPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDDDEDE 228
                QH+       + LL   +    Q +   EQ+ +G +L + LV+KL+ EN + +  
Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTDIAYYQRQRFCEQMVQGSQLTEILVRKLATENHNGKKN 180

Query: 229 D 229
           +
Sbjct: 181 E 181


>gi|239752894 PREDICTED: Neuroblastoma breakpoint family member
           6-like protein [Homo sapiens]
          Length = 298

 Score =  101 bits (252), Expect = 2e-21
 Identities = 67/181 (37%), Positives = 98/181 (54%), Gaps = 8/181 (4%)

Query: 57  MVVSAGPWSGEKAEMNILEINKKSRPQLAENKQQFRNLKQKCLVTQV-AYFLANRQNNYD 115
           M VSA    G +AE++ILE N+  R +L + KQ F++L +K L ++  AY L N    Y 
Sbjct: 1   MAVSATTCFGPRAEISILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60

Query: 116 YEDCKDLIKSMLRDERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQLREKLQEGRDA 175
            E+CKDLI+S+L +E    E +LAE    A  LR +  L+ +Q  ELT LR+K QEGR  
Sbjct: 61  CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKTQEGRGV 120

Query: 176 SRSLNQHL-------QALLTPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDDDEDE 228
                QH+       + LL        Q +   EQ+ +G +L + LV+KL  EN + +  
Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTGIAYYQRQRFCEQMVQGSQLTEILVRKLVTENHNGKKN 180

Query: 229 D 229
           +
Sbjct: 181 E 181


>gi|157311604 phosphodiesterase 4D interacting protein isoform 1 [Homo
            sapiens]
          Length = 2346

 Score = 79.0 bits (193), Expect = 1e-14
 Identities = 74/269 (27%), Positives = 122/269 (45%), Gaps = 22/269 (8%)

Query: 117  EDCKDLIKSMLRDERLLT----EEKLAEELGQAEELRQYKVLVHSQERELTQLREKLQEG 172
            +D + LI+ + + E  L     EEKLAEEL  A    +Y  L+  Q REL+ LR+K++EG
Sbjct: 1436 KDLESLIQRVSQLEAQLPKNGLEEKLAEELRSASWPGKYDSLIQDQARELSYLRQKIREG 1495

Query: 173  RDASRSLNQH-------LQALLTPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDDD 225
            R     + +H        + LL  ++ D   G+  REQLA+G +L + L  KLS ++   
Sbjct: 1496 RGICYLITRHAKDTVKSFEDLLRSNDIDYYLGQSFREQLAQGSQLTERLTSKLSTKDHKS 1555

Query: 226  EDEDVKVEEAEKVQELYAPREVQKAEEK-EVPEDSLEECAITCSNSHHPCESNQPYGNTR 284
            E +   +E       L   RE+Q+ E+  EV +  L+  ++T S+SH   +S++   +T 
Sbjct: 1556 EKDQAGLEPL----ALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSSTS 1611

Query: 285  ITFEEDQV--DSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPRNLQESEEEEAP 342
               +E +   D  ++   +H E   A    P +            +S +    S  + A 
Sbjct: 1612 FLSDELEACSDMDIVSEYTHYEEKKA---SPSHSDSIHHSSHSAVLSSKPSSTSASQGAK 1668

Query: 343  QESWDEGDWTLSIPPDMSASYQSDRSTFH 371
             ES +    +L  P +         S FH
Sbjct: 1669 AES-NSNPISLPTPQNTPKEANQAHSGFH 1696



 Score = 31.6 bits (70), Expect = 2.3
 Identities = 40/169 (23%), Positives = 70/169 (41%), Gaps = 38/169 (22%)

Query: 64  WSGEK------AEMNILEINKKSRPQLAENKQQFRNLKQKCLVTQVAYFLANRQNNYDYE 117
           W  EK       E NI  +N  S     +  Q+FR L Q             R N+    
Sbjct: 421 WEAEKYNEIRTQEQNIQHLNH-SLSHKEQLLQEFRELLQY------------RDNSDKTL 467

Query: 118 DCKDLIKSMLR----DERLLTEEKLAEELGQAEE----LRQYKVLVHSQERELTQLREKL 169
           +  +++   LR    D+ +  E  + E+    EE    LRQ ++ V  ++ +L +LR+ L
Sbjct: 468 EANEMLLEKLRQRIHDKAVALERAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRDVL 527

Query: 170 QEGRDASRSLNQHLQALLTPDEPDNSQGRDLREQLAEGCRLAQHLVQKL 218
                  +S+   L+A          +G ++ EQL+  C+  Q L +++
Sbjct: 528 SSNEATMQSMESLLRA----------KGLEV-EQLSTTCQNLQWLKEEM 565


>gi|7657138 golgi integral membrane protein 4 [Homo sapiens]
          Length = 696

 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 72/331 (21%), Positives = 129/331 (38%), Gaps = 65/331 (19%)

Query: 88  KQQFRNLKQKCLVTQVAYFLANRQNNYDYEDCKDLIKSMLRDERLLTEEKLA-EELGQAE 146
           ++Q R  K++    + A  L        Y   K +IK     E  L +++LA +++ +A+
Sbjct: 366 EEQDREWKEQHEQREAANLLEGHARAEVYPSAKPMIKFQSPYEEQLEQQRLAVQQVEEAQ 425

Query: 147 ELRQYKVLVHSQERELTQLREKLQEGRDASRSLNQHLQALLTPDEPDNSQGRDLREQLAE 206
           +LR+++  +H Q  +   LR++ Q+ +  +R +    QA L    P              
Sbjct: 426 QLREHQEALHQQRLQGHLLRQQEQQQQQVAREMALQRQAELEEGRP-------------- 471

Query: 207 GCRLAQHLVQKLSPENDDDEDEDVKVEEAEKVQELYAPREVQKAEEKEVPEDSLEECAIT 266
                QH  Q     + D  D D+                VQ AE++ +     EE A  
Sbjct: 472 -----QHQEQLRQQAHYDAMDNDI----------------VQGAEDQGIQG---EEGAYE 507

Query: 267 CSNSHHPCESNQPYGNTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKG 326
             N H       P GN     E+   ++                  PE+E+D    E+  
Sbjct: 508 RDNQHQDEAEGDP-GNRHEPREQGPREAD-----------------PESEADRAAVEDIN 549

Query: 327 PV-SPRNLQESEEEEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG 385
           P   P N  E E EEA Q   +      ++P +     QS++   ++  E+ + +A +  
Sbjct: 550 PADDPNNQGEDEFEEAEQVREE------NLPDENEEQKQSNQKQENTEVEEHLVMAGNPD 603

Query: 386 RHWCDQVKKEDQEATSPRLSRELLDEKEPEV 416
           +   D V ++ QE     +  +L +EK+ E+
Sbjct: 604 QQE-DNVDEQYQEEAEEEVQEDLTEEKKREL 633



 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 75/379 (19%), Positives = 151/379 (39%), Gaps = 52/379 (13%)

Query: 129 DERLLTEEKLAEELGQAEEL-RQYKVLVHSQERELTQLREKLQEGRDASRSLNQHLQALL 187
           + R   EE+  E++GQAE L  ++      Q+RE  +  E+    R+A+  L  H +A +
Sbjct: 338 EHRKALEEEEMEQVGQAEHLEEEHDPSPEEQDREWKEQHEQ----REAANLLEGHARAEV 393

Query: 188 TPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAEKVQELYAPREV 247
            P                     A+ +++  SP  +  E + + V++ E+ Q+L   RE 
Sbjct: 394 YPS--------------------AKPMIKFQSPYEEQLEQQRLAVQQVEEAQQL---REH 430

Query: 248 QKA------------EEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEE--DQVD 293
           Q+A            ++++  +    E A+         E  +P    ++  +   D +D
Sbjct: 431 QEALHQQRLQGHLLRQQEQQQQQVAREMAL---QRQAELEEGRPQHQEQLRQQAHYDAMD 487

Query: 294 STLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPRNLQESEEEEAPQESWDEGDWTL 353
           + ++   + D+ +       E ++ H+ E E  P +    +E    EA  ES  +     
Sbjct: 488 NDIV-QGAEDQGIQGEEGAYERDNQHQDEAEGDPGNRHEPREQGPREADPESEADRAAVE 546

Query: 354 SIPPDMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSRELLDEKE 413
            I P    + Q +   F   E+ +     D      ++ K+ +Q+  +  +   L+    
Sbjct: 547 DINPADDPNNQGE-DEFEEAEQVREENLPDEN----EEQKQSNQKQENTEVEEHLVMAGN 601

Query: 414 PEVLQDSLDRFYSTPFEYLELPDLCQPYRSDF-YSLQEQHLGLALDLDRMKKDQEEEEDQ 472
           P+  +D++D  Y    E     DL +  + +  ++ +E +     + D    D EE+E +
Sbjct: 602 PDQQEDNVDEQYQEEAEEEVQEDLTEEKKRELEHNAEETYGENDENTDDKNNDGEEQEVR 661

Query: 473 GPPCPRLSRELPEVVEPED 491
               P+   E  E  E E+
Sbjct: 662 DDNRPKGREEHYEEEEEEE 680



 Score = 36.2 bits (82), Expect = 0.095
 Identities = 35/167 (20%), Positives = 72/167 (43%), Gaps = 26/167 (15%)

Query: 109 NRQNNYDYEDCKDLIKSMLRDERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQLREK 168
           N Q   ++E+ + + +  L DE    E+K + +  +  E+ ++ V+  + +++   + E+
Sbjct: 555 NNQGEDEFEEAEQVREENLPDEN--EEQKQSNQKQENTEVEEHLVMAGNPDQQEDNVDEQ 612

Query: 169 LQEGRDASRSLNQHLQALLTPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDDDEDE 228
            QE                   E +     DL E   E  R  +H  ++   END++ D+
Sbjct: 613 YQE-------------------EAEEEVQEDLTE---EKKRELEHNAEETYGENDENTDD 650

Query: 229 DVKVEEAEKVQELYAPREVQKAEEKEVPEDSLEECAITCSNSHHPCE 275
                E ++V++   P+  ++  E+E  E+  E+ A     SH   E
Sbjct: 651 KNNDGEEQEVRDDNRPKGREEHYEEE--EEEEEDGAAVAEKSHRRAE 695


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 96/444 (21%), Positives = 176/444 (39%), Gaps = 67/444 (15%)

Query: 73  ILEINKKSRPQLAENKQQFRNLKQKCLVTQVAYFLANRQNNYDYEDCKDLIK--SMLRDE 130
           +LE+ +K R    E KQQ R  +Q  +              +  E+ K+  K  ++LR E
Sbjct: 215 LLELRRKGR----EEKQQQRRERQDRV--------------FQEEEEKEWRKRETVLRKE 256

Query: 131 RLLTEEKLAEELGQAE-ELRQYKVLVHSQERELTQLREKLQEGRDASRSLNQHLQALLTP 189
               EEKL EE  Q + EL++ +  +   ER+  +LR + QE     + L +  Q     
Sbjct: 257 ----EEKLQEEEPQRQRELQEEEEQLRKLERQ--ELRRERQEEEQQQQRLRREQQLRRKQ 310

Query: 190 DEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAEKVQELYAPREVQK 249
           +E    Q  + REQ     +  +   Q+L  E ++  ++ ++ E+ E+ +E    +++++
Sbjct: 311 EEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERRE----QQLRR 366

Query: 250 AEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTLIDSSSHDEWLDAV 309
            +E+E  E  L                 Q     +    E Q+           +     
Sbjct: 367 EQEEERREQQLRR--------EQQLRREQQLRREQQLRREQQLRREQ-QLRREQQLRREQ 417

Query: 310 CIIPENESDHEQEEEKGPVSPRNLQESEEEEAPQESWDEGDWTLSIPPDMSASYQSDRST 369
            +  E +   EQEEE+     ++ QE  E+   +E  +  DW       +    +++R  
Sbjct: 418 QLRREQQLRREQEEERH--EQKHEQERREQRLKREQEERRDW-------LKREEETER-- 466

Query: 370 FHSVEEQQVGLALD----IGRHWC---DQVKKEDQEATSPRLSRELLDEKEPEV-LQDSL 421
            H  E ++  L  D        W    ++ ++E QE    +L RE  + +E  +  Q+  
Sbjct: 467 -HEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEE 525

Query: 422 DRFYSTPFEYLELPDLCQPYRSDFYSLQEQ-HLGLALDLDRMKKDQEEEEDQ------GP 474
           +R         +L    +  R      +E+  L       R+K++QEE  DQ        
Sbjct: 526 ERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEER 585

Query: 475 PCPRLSRELPEVVEPEDLQDSLDR 498
              RL RE  E +E    ++ ++R
Sbjct: 586 RQQRLKREQEERLEQRLKREEVER 609



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 91/447 (20%), Positives = 174/447 (38%), Gaps = 72/447 (16%)

Query: 128 RDERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQLREKLQEGRDASRSLNQHLQALL 187
           RD+ L  E          EE RQ ++    +ER   +L+ +  E  +      Q L+   
Sbjct: 575 RDQLLKRE----------EERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKR-- 622

Query: 188 TPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAEKVQELYAPRE- 246
             +EP+  +    R+QL +     +   Q+L  E  +  ++ +K EE E+  E    RE 
Sbjct: 623 --EEPEEER----RQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREH 676

Query: 247 VQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTLIDSSSHDEWL 306
            ++  E+E+ E+  E+       +    +S  P    ++  E D   S +          
Sbjct: 677 EEERREQELAEEEQEQ-------ARERIKSRIPKWQWQLESEADARQSKVYSRPRKQ--- 726

Query: 307 DAVCIIPENESDHEQEEEKGPVSPRNLQESEEEEAPQESWDEGDWTLSIPPDMSASYQSD 366
                  E +   +++EEK       LQ  EEE A ++  +E         D +  +Q++
Sbjct: 727 -------EGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQ-----RRDFTWQWQAE 774

Query: 367 RSTFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYS 426
             +      Q++     +      Q++ E+++    R     L E+E +  +    R   
Sbjct: 775 EKSERG--RQRLSARPPLREQRERQLRAEERQQREQR----FLPEEEEKEQRRRQRRERE 828

Query: 427 TPFEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEV 486
              ++LE  +  Q  R     LQE+  GL  D +R ++ QE+  DQ              
Sbjct: 829 KELQFLEEEEQLQ-RRERAQQLQEEEDGLQEDQER-RRSQEQRRDQ-------------- 872

Query: 487 VEPEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEED 546
                L++   R   T ++ P L +  +         EEE     L  +E EK +  E++
Sbjct: 873 KWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEE-----LQREEREKRRRQEQE 927

Query: 547 QKPPCPRLNEVLMEAEEPEVLQDSLDR 573
           ++       E  ++ EE ++L++  ++
Sbjct: 928 RQ----YREEEQLQQEEEQLLREEREK 950



 Score = 38.5 bits (88), Expect = 0.019
 Identities = 52/233 (22%), Positives = 90/233 (38%), Gaps = 40/233 (17%)

Query: 129  DERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQLREKLQEGRDASRSLN-------Q 181
            +E L  EE+  E+  + E+ RQY+     Q+ E   LRE+ ++ R   R          Q
Sbjct: 910  EEELQREER--EKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQ 967

Query: 182  HLQALLTPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDD----------DEDEDVK 231
              +  L  +EP+  + ++  ++  E   L Q   Q L  E +            + ++++
Sbjct: 968  QKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQ 1027

Query: 232  VEEAEKVQELYAPREVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQ 291
             EE + ++E    R +Q+ E +   E+ L++            E  Q  G  R T    +
Sbjct: 1028 QEEEQLLREEREKRRLQERERQYREEEELQQ------------EEEQLLGEERETRRRQE 1075

Query: 292  VDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPRNLQESEEEEAPQE 344
            ++          +         E E    +E EK     R  Q  EEEE  QE
Sbjct: 1076 LERQYRKEEELQQ---------EEEQLLREEPEKRRRQERERQCREEEELQQE 1119



 Score = 37.4 bits (85), Expect = 0.042
 Identities = 89/432 (20%), Positives = 162/432 (37%), Gaps = 51/432 (11%)

Query: 68  KAEMNILEINKKSRPQLAENKQQFRNLKQKCLVTQVAYFLANRQNNYDYEDCKDLIKSML 127
           K E    E  ++ R Q    +QQ    +Q+    Q       R+     E  ++  +  L
Sbjct: 309 KQEEERREQQEERREQQERREQQEERREQQLRREQEE----RREQQLRREQEEERREQQL 364

Query: 128 RDERLLTEEKLAEELGQAEELRQYKVLVHSQE-RELTQLREKLQEGRDASRSLNQHLQAL 186
           R E+   EE+  ++L + ++LR+ + L   Q+ R   QLR + Q  R+      Q L+  
Sbjct: 365 RREQ--EEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR- 421

Query: 187 LTPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAEKVQELYAPRE 246
                 +    R+  E+  E     +   Q+L  E ++  D   + EE E+ ++    ++
Sbjct: 422 ------EQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQ 475

Query: 247 VQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTLIDSSSHDEWL 306
           +++ +E+E  E  L+                Q     ++  E+++     +     +E L
Sbjct: 476 LKRDQEEERRERWLK-------LEEEERREQQERREQQLRREQEERREQRLKRQEEEERL 528

Query: 307 DAVCIIPENESDHEQEEEKGPVSPRN-----LQESEEEEAPQESWDEGDWTLSIPPDMSA 361
               +  E +   EQEE +  +  R       QE  E+   +E  +  D  L        
Sbjct: 529 QQ-RLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLL-------- 579

Query: 362 SYQSDRSTFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSL 421
             + +R       EQ+  L   + R   +++  E +E    RL RE   E E E  Q  L
Sbjct: 580 KREEERRQQRLKREQEERLEQRLKREEVERL--EQEERREQRLKRE---EPEEERRQQLL 634

Query: 422 DRFYSTPFEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMKKDQEE--------EEDQG 473
                      +L    Q  R      +E+   L     R+K++ EE        EE+Q 
Sbjct: 635 KSEEQEERRQQQLRREQQERREQRLKREEEEERLE---QRLKREHEEERREQELAEEEQE 691

Query: 474 PPCPRLSRELPE 485
               R+   +P+
Sbjct: 692 QARERIKSRIPK 703



 Score = 36.6 bits (83), Expect = 0.072
 Identities = 83/429 (19%), Positives = 171/429 (39%), Gaps = 53/429 (12%)

Query: 67   EKAEMNILEINKKSRPQLAENKQQFRNLKQKCLVTQVAYFLAN---------RQNNY-DY 116
            ++ E  + E  +K R Q  E ++Q+R  K K L  +    L           R+  Y + 
Sbjct: 938  QEEEQLLREEREKRRRQ--ERERQYR--KDKKLQQKEEQLLGEEPEKRRRQEREKKYREE 993

Query: 117  EDCKDLIKSMLRDER-LLTEEKLAEELGQAEELRQYKVLVHSQERELTQLREKLQEGRDA 175
            E+ +   + +LR+ER     ++   +  + +EL+Q +  +  +ERE  +L+E+ ++ R+ 
Sbjct: 994  EELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYRE- 1052

Query: 176  SRSLNQHLQALLTPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDD----------D 225
               L Q  + LL  +E +  + ++L  Q  +   L Q   Q L  E +            
Sbjct: 1053 EEELQQEEEQLL-GEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCR 1111

Query: 226  EDEDVKVEEAEKVQELYAPREVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRI 285
            E+E+++ EE + ++E    R  Q+ E +   E+ +++               +P    R 
Sbjct: 1112 EEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQ-------EEEQLLREEPEKRRRQ 1164

Query: 286  TFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPRNLQESEEEEAPQES 345
              E    +   +             ++ E +    QE E+       LQ  + ++  ++ 
Sbjct: 1165 ELERQYREEEELQQEEEQ-------LLREEQEKRRQERERQYREEEELQRQKRKQRYRDE 1217

Query: 346  WDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVK-KEDQEATSPRL 404
                D      P+   + + ++      E +Q     D       Q++ ++ Q+     L
Sbjct: 1218 DQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLED------SQLRDRQSQQDLQHLL 1271

Query: 405  SRELLDEKEPEVLQ-DSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMK 463
              +   ++E E  +    DR +    E LE  +  +  R D  S +E+ L   L  +R +
Sbjct: 1272 GEQQERDREQERRRWQQRDRHFPEE-EQLEREEQKEAKRRDRKSQEEKQL---LREEREE 1327

Query: 464  KDQEEEEDQ 472
            K + +E D+
Sbjct: 1328 KRRRQETDR 1336



 Score = 36.2 bits (82), Expect = 0.095
 Identities = 43/199 (21%), Positives = 86/199 (43%), Gaps = 10/199 (5%)

Query: 66   GEKAEMNILEINKKSRPQLAENKQQFRNLK----QKCLVTQVAYFLANRQNNYDYEDCKD 121
            GE+ ++   E ++K R +  + ++Q R  K    ++ L  Q        +     E  ++
Sbjct: 1679 GEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQE 1738

Query: 122  LIKSMLRDERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQLREKLQ-EGRDASRSLN 180
             ++   R  ++L EE+L  E  + +  RQ +     +E +L Q RE+ Q   +++ R   
Sbjct: 1739 QLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFR 1798

Query: 181  QHLQALLTPDEPD-NSQGRDLREQLAEGCRLAQHLVQKLSPEND----DDEDEDVKVEEA 235
            +  Q     +E     Q RD + +  E     +   Q+L  E D     +E    + +  
Sbjct: 1799 EEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSR 1858

Query: 236  EKVQELYAPREVQKAEEKE 254
             + QEL+   E ++ +E+E
Sbjct: 1859 REEQELWQEEEQKRRQERE 1877



 Score = 34.3 bits (77), Expect = 0.36
 Identities = 78/392 (19%), Positives = 151/392 (38%), Gaps = 55/392 (14%)

Query: 127  LRDERLLTEEKLAEELGQAEELRQYKVLVHSQEREL-----TQLREKLQEGRDASRSLNQ 181
            L +ER      L  +    E+LR+ + L+  +E EL      + R + QE +       Q
Sbjct: 878  LEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQ 937

Query: 182  HLQALLTPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDD----------DEDEDVK 231
              +  L  +E +  + ++   Q  +  +L Q   Q L  E +            E+E+++
Sbjct: 938  QEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQ 997

Query: 232  VEEAEKVQELYAPREVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQ 291
             EE + ++E    R  Q+ E +   +D L++            E  +     R   EE++
Sbjct: 998  QEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREER--EKRRLQERERQYREEEE 1055

Query: 292  VDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPRNLQESEEEEAPQESWDEGDW 351
            +          +E L    +  E E+   QE E+       LQ+ EE+   +E       
Sbjct: 1056 L-------QQEEEQL----LGEERETRRRQELERQYRKEEELQQEEEQLLREE------- 1097

Query: 352  TLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSRELLDE 411
                 P+     + +R      E QQ    L         +++E ++     L R+  +E
Sbjct: 1098 -----PEKRRRQERERQCREEEELQQEEEQL---------LREEREKRRRQELERQYREE 1143

Query: 412  KEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMKKDQEEEED 471
            +E +  ++ L R    P E     +L + YR +    QE+   L  + ++ ++++E +  
Sbjct: 1144 EEVQQEEEQLLR--EEP-EKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYR 1200

Query: 472  QGPPCPRLSRELPEVVEPEDLQDSLDRWYSTP 503
            +     R  R+  +    ED +  L +W   P
Sbjct: 1201 EEEELQRQKRK--QRYRDEDQRSDL-KWQWEP 1229



 Score = 31.6 bits (70), Expect = 2.3
 Identities = 42/243 (17%), Positives = 89/243 (36%), Gaps = 26/243 (10%)

Query: 198 RDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAEKV---QELYAPR-EVQKAEEK 253
           R L E+  +  R  +   ++   E ++  ++  ++E+ ++    +EL+  R E Q+ EE+
Sbjct: 127 RQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREER 186

Query: 254 EVPEDSLEECAITCSNSHHPCESN---------QPYGNTRITFEEDQVDSTLIDSSSHDE 304
              E+ L+ C         P E           +  G      +  +    +       E
Sbjct: 187 RAEEEQLQSCK-GHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKE 245

Query: 305 WLDAVCIIPENESDHEQEEEKGPVSPRNLQESEEE---------EAPQESWDEGDWTLSI 355
           W     ++ + E   ++EE   P   R LQE EE+            ++  ++    L  
Sbjct: 246 WRKRETVLRKEEEKLQEEE---PQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRR 302

Query: 356 PPDMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSRELLDEKEPE 415
              +    + +R        +Q             Q+++E +E    +L RE  +E+  +
Sbjct: 303 EQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQ 362

Query: 416 VLQ 418
            L+
Sbjct: 363 QLR 365



 Score = 31.6 bits (70), Expect = 2.3
 Identities = 44/224 (19%), Positives = 84/224 (37%), Gaps = 16/224 (7%)

Query: 128  RDERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQLREKLQEGRDASRSLNQHLQALL 187
            RD + L EE       + ++LR      H ++R+  +  + LQEG +      +  +   
Sbjct: 1641 RDRKFLEEEPQLRRQEREQQLR------HDRDRKFREEEQLLQEGEEQQLRRQERDRKFR 1694

Query: 188  TPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPE---NDDDEDEDVKVEEAEK----VQE 240
              ++    Q R+ +    E     Q L +K   E     + E E ++ +E  +     ++
Sbjct: 1695 EEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQ 1754

Query: 241  LYAPREVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTLIDSS 300
            L   RE Q+   +E      EE  +          S +   + R   EE+Q+     +  
Sbjct: 1755 LRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQE---SDRKFREEEQLRQEREEQQ 1811

Query: 301  SHDEWLDAVCIIPENESDHEQEEEKGPVSPRNLQESEEEEAPQE 344
               +  D      E +   E++E++          +EE+ A QE
Sbjct: 1812 LRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQE 1855



 Score = 30.0 bits (66), Expect = 6.8
 Identities = 64/356 (17%), Positives = 141/356 (39%), Gaps = 33/356 (9%)

Query: 128  RDERLLTEEKLAEELGQAEELRQYKV--LVHSQE-RELTQLREKLQEGRDASRSLNQHLQ 184
            R+E  L +E+  + L + E  R+++   L H ++ R+  +  ++L+      + L +  Q
Sbjct: 1339 REEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQ 1398

Query: 185  ALLTPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAEKVQELYAP 244
                  E    Q RD + +  E     Q   +K   E      ++ + +  E+ Q+L   
Sbjct: 1399 LRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQE 1458

Query: 245  REVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTLIDSSSHDE 304
            R  +  EE+++ ++  E+            + ++   + +   EE Q+     D    ++
Sbjct: 1459 RHRKFREEEQLLQEREEQ------------QLHRQERDRKFLEEEQQLRRQERDRKFREQ 1506

Query: 305  WLDAVCIIPENESDHEQEEEKGPVSPRNLQESEEEEAPQESWDEGDWTLSIPPDMSASYQ 364
             L +    PE +   E+++       R   + E++   QE   +         D    ++
Sbjct: 1507 ELRSQ--EPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQR------RQDRDRKFR 1558

Query: 365  SDRSTFHSVEEQQVGLALDIGRHWCDQ--VKKEDQEATSPRLSRELLDEKEPEVLQDSLD 422
             +       EEQQ+       +   ++  V++++QE       ++L  ++  + L+   D
Sbjct: 1559 EEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERD 1618

Query: 423  RFYSTPFEYLELPDLCQPYR--------SDFYSLQEQHLGLALDLDRMKKDQEEEE 470
            R +    + L+  +  Q +R         +   L+ Q     L  DR +K +EEE+
Sbjct: 1619 RKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQ 1674


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 899

 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 78/361 (21%), Positives = 144/361 (39%), Gaps = 28/361 (7%)

Query: 52  ATNVSMVVSAGPWSGEKAEMNILEINKKSRP---QLAENKQQFRNLKQKCLVTQVAYFLA 108
           A  +   +SA     +KA+  I E+ K+      +L  N      LK+K    Q    LA
Sbjct: 178 AGELQRALSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLA 237

Query: 109 NRQNNYDYEDCKDLIKSMLRDERLLTEEK---LAEELG-QAEELRQYKVLVHSQERELTQ 164
             + +    + K+L + + R + LL + +   L EE+  Q EELR+ +  +  QE ++ +
Sbjct: 238 ESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWR 297

Query: 165 LREKL--QEG--RDASRSLNQHLQALLTPDEPDNSQGRDLREQ--LAEGCRLAQHLVQKL 218
             E+L  QEG  R+    + +  + L   ++    Q ++LREQ  L E     Q   +K+
Sbjct: 298 QEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKM 357

Query: 219 SPENDDDEDEDVKV-EEAEKVQELYAPREVQKAEEKEVPEDSLEECAITCSNSHHPCESN 277
             + +   +++ K+  + E++ E       Q+ + ++  E   E+            E  
Sbjct: 358 WEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQE 417

Query: 278 QPYGNTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPRNLQESE 337
           + +       EE ++      +   +E +     I E E    +EEE        +Q+ E
Sbjct: 418 KMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQE 477

Query: 338 EEEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVKKEDQ 397
           E    QE   E +W     P+              ++EQ+  +       W  + K  DQ
Sbjct: 478 ENMWEQE---EKEWQQQRLPEQKEKLWEQ----EKMQEQEEKI-------WEQEEKIRDQ 523

Query: 398 E 398
           E
Sbjct: 524 E 524



 Score = 39.7 bits (91), Expect = 0.009
 Identities = 53/285 (18%), Positives = 117/285 (41%), Gaps = 61/285 (21%)

Query: 66  GEKAEMNILEINKKSRPQLAENKQQFRNLKQKCLVTQVAYFLANRQNNYDYEDCKDLIKS 125
           G++ +M   E  ++   Q+ E +++ R+ +QK         + +++   + +  +   K+
Sbjct: 528 GQEKKMWRQEKMREQEDQMWEQEEKMRDQEQK---------MWDQEERMEKKTQEQEKKT 578

Query: 126 MLRDERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQLREKLQEGRDASRSLNQHLQA 185
             ++E++  EE++ E   + +++R+ + ++  QE ++ +  EK+QE  +      + +Q 
Sbjct: 579 WDQEEKMREEERMRE---REKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQE 635

Query: 186 LLTPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAEKVQELYAPR 245
                     +  +  E++ E  RL         PE  +   E  K++E EK+QE     
Sbjct: 636 QEEKMWEQEEKMWEQEEKMWEQQRL---------PEQKEKLWEHEKMQEQEKMQE----- 681

Query: 246 EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTLIDSSSHDEW 305
           + +K  E+E  E   +E            +  + +   ++  EE                
Sbjct: 682 QEEKIWEQEKMEKKTQE------------QEKKTWDQEKMREEES--------------- 714

Query: 306 LDAVCIIPENESDHEQEEEKGPVSPRNLQESEEE--EAPQESWDE 348
                 + E E    +EEE        +QE EE+  E  +E W++
Sbjct: 715 ------MREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQ 753



 Score = 36.2 bits (82), Expect = 0.095
 Identities = 60/314 (19%), Positives = 129/314 (41%), Gaps = 37/314 (11%)

Query: 128 RDERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQLREKLQEG---RDASRSLNQHLQ 184
           ++ER+  +EK+ E   Q E++R+ K +   QE++     EK+QE    R+  + + +  +
Sbjct: 409 KEERMREQEKMWE---QVEKMREEKKM-QEQEKKTRDQEEKMQEEERIREREKKMREEEE 464

Query: 185 ALLTPDEPDNSQGRDLREQLAEGCRLAQ--HLVQKLSPENDDDEDEDVKVEEAEKV---- 238
            +   +E    Q  ++ EQ  +  +  +     +KL  +    E E+   E+ EK+    
Sbjct: 465 TMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQE 524

Query: 239 -----------QELYAPREVQKAEEKEVPEDSLEECAITCSNSHHPCESNQP--YGNTRI 285
                      QE    +E Q  E++E   D  ++            +  +   +     
Sbjct: 525 EMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEK 584

Query: 286 TFEEDQVDSTLIDSSSHDEWL-DAVCIIPENESDHEQEEEKGPVSPRNLQESEEE--EAP 342
             EE+++          +E + +    + E E   +++EEK       +QE EE+  E  
Sbjct: 585 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQE 644

Query: 343 QESWDEGD--WTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIGRHW-CDQVKKEDQEA 399
           ++ W++ +  W     P+     Q ++   H   ++Q  +     + W  ++++K+ QE 
Sbjct: 645 EKMWEQEEKMWEQQRLPE-----QKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQ 699

Query: 400 TSPRLSRELLDEKE 413
                 +E + E+E
Sbjct: 700 EKKTWDQEKMREEE 713


>gi|68077166 DnaJ homology subfamily A member 5 isoform 2 [Homo
           sapiens]
          Length = 531

 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 73/343 (21%), Positives = 132/343 (38%), Gaps = 67/343 (19%)

Query: 77  NKKSRPQLAENKQQFRNLKQKCLVTQVAYFLANRQNNYDYEDCKDLIKSMLRDERLLTEE 136
           NKK R +  + K +        LV Q+  F+  R                ++  R L EE
Sbjct: 188 NKKIRDKARKEKNE--------LVRQLVAFIRKRDKR-------------VQAHRKLVEE 226

Query: 137 KLAEELGQAEELRQYKVLVHSQERELTQLREKLQEGRDASRSLNQHLQALLTPDEPDNSQ 196
           + AE+  +AEE+R+ + L   Q + + Q RE   +      +L + LQ +    E +   
Sbjct: 227 QNAEKARKAEEMRRQQKL--KQAKLVEQYRE---QSWMTMANLEKELQEMEARYEKEFGD 281

Query: 197 GRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAEKVQELYAPR-----EVQKAE 251
           G D  E       + +H ++    + +D +D D + E+AE   +LY P      + +KA 
Sbjct: 282 GSDENE-------MEEHELK----DEEDGKDSD-EAEDAELYDDLYCPACDKSFKTEKAM 329

Query: 252 EKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTLIDSSSHDEWLDAVCI 311
           +         E            E N         F   Q+D   +D +S +E  DA   
Sbjct: 330 KNHEKSKKHREMVALLKQQLEEEEEN---------FSRPQIDENPLDDNSEEEMEDA--- 377

Query: 312 IPENESDHEQEEEKGPVSPRNLQESEEEEAPQESWDEGDWTLSIPPDMSASYQSDRSTFH 371
            P+ +   +Q+++K   + +N  ++     P E        + + P+ +   Q       
Sbjct: 378 -PKQKLSKKQKKKKQKPA-QNYDDNFNVNGPGEG-------VKVDPEDTNLNQDSAKELE 428

Query: 372 SVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSRELLDEKEP 414
              ++ V +   I    CD  K E +    P+  ++  D K+P
Sbjct: 429 DSPQENVSVTEIIKP--CDDPKSEAKSVPKPK-GKKTKDMKKP 468


>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
          Length = 1780

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 46/234 (19%), Positives = 105/234 (44%), Gaps = 27/234 (11%)

Query: 117  EDCKDLIKSM--LRDERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQLREKLQEGRD 174
            E  +D +K+   L  + L  +E++ +     ++++    L   +E    Q  EKL+E   
Sbjct: 1166 EHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELS 1225

Query: 175  ASRSLNQHLQALLTPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEE 234
            AS +  Q+L+A L   E D +   DL+E+L +  +  + + +++S   D+D+   +K+ E
Sbjct: 1226 ASSARTQNLKADLQRKEEDYA---DLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINE 1282

Query: 235  AEKVQELYAPREVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDS 294
             EK       ++ Q ++E ++ + ++++               +   N ++     Q + 
Sbjct: 1283 LEK-------KKNQCSQELDMKQRTIQQL-------------KEQLNNQKVEEAIQQYER 1322

Query: 295  TLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPRNLQESEEEEAPQESWDE 348
               D +  ++ ++ + +  E +   + E+++  V    L+E E      E W E
Sbjct: 1323 ACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQ--VLEAKLEEVERLATELEKWKE 1374



 Score = 30.8 bits (68), Expect = 4.0
 Identities = 36/164 (21%), Positives = 75/164 (45%), Gaps = 25/164 (15%)

Query: 109  NRQNNYD------YEDCKDLIKSMLRDERLLTEEKLAEELGQAEELRQYKVLVHSQEREL 162
            NR+N++       +E+CK+++K+  +    +      EEL Q  E  Q +V  +  E   
Sbjct: 1008 NRENSFHSSIEAIWEECKEIVKASSKKSHQI------EELEQQIEKLQAEVKGYKDEN-- 1059

Query: 163  TQLREKLQEGRDASRSLNQHLQALLTPDEPDNSQGRDLR-EQLAEGCRLAQHLVQKLSPE 221
             +L+EK  + +D      + L   L  +  + +   D++ + + EG R    L Q ++  
Sbjct: 1060 NRLKEKEHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGKRALSELTQGVTCY 1119

Query: 222  NDDDEDEDVKVEEAEKVQELYAPREVQKAEEKEVPEDSLEECAI 265
                     K++E E + E    ++V+ +   ++ +D LE+ +I
Sbjct: 1120 K-------AKIKELETILE---TQKVECSHSAKLEQDILEKESI 1153


>gi|115334679 retinoblastoma-binding protein 1 isoform III [Homo
           sapiens]
          Length = 1188

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 81/357 (22%), Positives = 150/357 (42%), Gaps = 54/357 (15%)

Query: 117 EDCKDLIKSMLRDERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQLREKLQEGRDAS 176
           E+ KDL +SM    +L  E  L E   + EE          +E EL   R + +  RD +
Sbjct: 419 EEKKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIARDVN 478

Query: 177 RSLNQHLQALLTPDE--PDNSQGRDLREQLAEGCRLAQHLV-----------QKLSPEND 223
            S+ + ++   T D+   ++++ +D+ +      +    L+           +K+  + D
Sbjct: 479 -SIKKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQED 537

Query: 224 DDEDEDVKVEEAEKVQELYAPREVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNT 283
            D+D D   EE EK QE     E +   E E  E+ +E C      +    +     G T
Sbjct: 538 SDKDSD---EEEEKSQE-REETESKCDSEGEEDEEDMEPCL-----TGTKVKVKYGRGKT 588

Query: 284 RITFEEDQVDSTLIDSSS-------------HDEWLDAVCII-PENESDHEQEEEKGPVS 329
           +  +E   + ST ID                +DEW+ A  II P ++   +++++K    
Sbjct: 589 QKIYEA-SIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKK---K 644

Query: 330 PRNLQESEEEEAPQESWDEG-------DWTLS--IPPDMSASYQSDRSTFHSVEEQQVGL 380
            +N ++SE++E   E   +          TLS  +P  +S +  S+  +     + +   
Sbjct: 645 AKNKEDSEKDEKRDEERQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSDSETED 704

Query: 381 ALDIGRHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSL---DRFYSTPFEYLEL 434
           AL+      +++  +D+   +  L+ + LDE+ P++    L   DR    P E L+L
Sbjct: 705 ALE-KNLINEELSLKDELEKNENLNDDKLDEENPKISAHILKENDRTQMQPLETLKL 760


>gi|115334673 retinoblastoma-binding protein 1 isoform II [Homo
           sapiens]
          Length = 1203

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 81/357 (22%), Positives = 150/357 (42%), Gaps = 54/357 (15%)

Query: 117 EDCKDLIKSMLRDERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQLREKLQEGRDAS 176
           E+ KDL +SM    +L  E  L E   + EE          +E EL   R + +  RD +
Sbjct: 419 EEKKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIARDVN 478

Query: 177 RSLNQHLQALLTPDE--PDNSQGRDLREQLAEGCRLAQHLV-----------QKLSPEND 223
            S+ + ++   T D+   ++++ +D+ +      +    L+           +K+  + D
Sbjct: 479 -SIKKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQED 537

Query: 224 DDEDEDVKVEEAEKVQELYAPREVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNT 283
            D+D D   EE EK QE     E +   E E  E+ +E C      +    +     G T
Sbjct: 538 SDKDSD---EEEEKSQE-REETESKCDSEGEEDEEDMEPCL-----TGTKVKVKYGRGKT 588

Query: 284 RITFEEDQVDSTLIDSSS-------------HDEWLDAVCII-PENESDHEQEEEKGPVS 329
           +  +E   + ST ID                +DEW+ A  II P ++   +++++K    
Sbjct: 589 QKIYEA-SIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKK---K 644

Query: 330 PRNLQESEEEEAPQESWDEG-------DWTLS--IPPDMSASYQSDRSTFHSVEEQQVGL 380
            +N ++SE++E   E   +          TLS  +P  +S +  S+  +     + +   
Sbjct: 645 AKNKEDSEKDEKRDEERQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSDSETED 704

Query: 381 ALDIGRHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSL---DRFYSTPFEYLEL 434
           AL+      +++  +D+   +  L+ + LDE+ P++    L   DR    P E L+L
Sbjct: 705 ALE-KNLINEELSLKDELEKNENLNDDKLDEENPKISAHILKENDRTQMQPLETLKL 760


>gi|115334677 retinoblastoma-binding protein 1 isoform I [Homo
           sapiens]
          Length = 1257

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 81/357 (22%), Positives = 150/357 (42%), Gaps = 54/357 (15%)

Query: 117 EDCKDLIKSMLRDERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQLREKLQEGRDAS 176
           E+ KDL +SM    +L  E  L E   + EE          +E EL   R + +  RD +
Sbjct: 419 EEKKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIARDVN 478

Query: 177 RSLNQHLQALLTPDE--PDNSQGRDLREQLAEGCRLAQHLV-----------QKLSPEND 223
            S+ + ++   T D+   ++++ +D+ +      +    L+           +K+  + D
Sbjct: 479 -SIKKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQED 537

Query: 224 DDEDEDVKVEEAEKVQELYAPREVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNT 283
            D+D D   EE EK QE     E +   E E  E+ +E C      +    +     G T
Sbjct: 538 SDKDSD---EEEEKSQE-REETESKCDSEGEEDEEDMEPCL-----TGTKVKVKYGRGKT 588

Query: 284 RITFEEDQVDSTLIDSSS-------------HDEWLDAVCII-PENESDHEQEEEKGPVS 329
           +  +E   + ST ID                +DEW+ A  II P ++   +++++K    
Sbjct: 589 QKIYEA-SIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKK---K 644

Query: 330 PRNLQESEEEEAPQESWDEG-------DWTLS--IPPDMSASYQSDRSTFHSVEEQQVGL 380
            +N ++SE++E   E   +          TLS  +P  +S +  S+  +     + +   
Sbjct: 645 AKNKEDSEKDEKRDEERQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSDSETED 704

Query: 381 ALDIGRHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSL---DRFYSTPFEYLEL 434
           AL+      +++  +D+   +  L+ + LDE+ P++    L   DR    P E L+L
Sbjct: 705 ALE-KNLINEELSLKDELEKNENLNDDKLDEENPKISAHILKENDRTQMQPLETLKL 760


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.130    0.381 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,033,865
Number of Sequences: 37866
Number of extensions: 1475535
Number of successful extensions: 10597
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 96
Number of HSP's successfully gapped in prelim test: 538
Number of HSP's that attempted gapping in prelim test: 7389
Number of HSP's gapped (non-prelim): 2176
length of query: 633
length of database: 18,247,518
effective HSP length: 108
effective length of query: 525
effective length of database: 14,157,990
effective search space: 7432944750
effective search space used: 7432944750
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.