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Search of human proteins with 89111941
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|89111941 myotubularin related protein 11 isoform b [Homo
sapiens]
(640 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|89111941 myotubularin related protein 11 isoform b [Homo sapi... 1327 0.0
gi|224994251 myotubularin related protein 11 isoform a [Homo sap... 1296 0.0
gi|124028527 myotubularin related protein 10 [Homo sapiens] 294 2e-79
gi|94721263 myotubularin related protein 12 [Homo sapiens] 209 5e-54
gi|19923424 myotubularin related protein 9 [Homo sapiens] 150 5e-36
gi|44680154 myotubularin-related protein 2 isoform 1 [Homo sapiens] 141 2e-33
gi|41350318 myotubularin-related protein 2 isoform 2 [Homo sapiens] 141 2e-33
gi|41350316 myotubularin-related protein 2 isoform 2 [Homo sapiens] 141 2e-33
gi|28872761 myotubularin-related protein 1 [Homo sapiens] 137 3e-32
gi|4557896 myotubularin [Homo sapiens] 127 2e-29
gi|21361759 myotubularin related protein 8 [Homo sapiens] 108 2e-23
gi|217272865 myotubularin related protein 4 [Homo sapiens] 102 1e-21
gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens] 102 1e-21
gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens] 102 1e-21
gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens] 102 1e-21
gi|134142348 myotubularin related protein 6 [Homo sapiens] 99 9e-21
gi|225543474 myotubularin related protein 7 [Homo sapiens] 94 4e-19
gi|239735519 SET binding factor 1 [Homo sapiens] 93 9e-19
gi|29788755 SET binding factor 2 [Homo sapiens] 92 1e-18
gi|239756935 PREDICTED: hypothetical protein XP_002345110 [Homo ... 36 0.12
gi|239751447 PREDICTED: hypothetical protein XP_002347851 [Homo ... 36 0.12
gi|239745952 PREDICTED: hypothetical protein XP_002343584 [Homo ... 35 0.21
gi|195963410 MEF2 activating motif and SAP domain containing tra... 32 1.4
gi|239752306 PREDICTED: hypothetical protein XP_002348194 [Homo ... 32 1.8
gi|239746817 PREDICTED: hypothetical protein XP_002343856 [Homo ... 32 1.8
gi|38424083 short-chain dehydrogenase/reductase 10 isoform d [Ho... 32 2.3
gi|38424075 short-chain dehydrogenase/reductase 10 isoform a [Ho... 32 2.3
gi|38424079 short-chain dehydrogenase/reductase 10 isoform c [Ho... 32 2.3
gi|38424085 short-chain dehydrogenase/reductase 10 isoform b [Ho... 32 2.3
gi|169173184 PREDICTED: hypothetical protein [Homo sapiens] 31 3.1
>gi|89111941 myotubularin related protein 11 isoform b [Homo
sapiens]
Length = 640
Score = 1327 bits (3434), Expect = 0.0
Identities = 640/640 (100%), Positives = 640/640 (100%)
Query: 1 MPPRVTFQPCGWQWNQDTPLNSEYDFALVNIGRLEAVSGLSRVQLLRPGSLHKFIPEEIL 60
MPPRVTFQPCGWQWNQDTPLNSEYDFALVNIGRLEAVSGLSRVQLLRPGSLHKFIPEEIL
Sbjct: 1 MPPRVTFQPCGWQWNQDTPLNSEYDFALVNIGRLEAVSGLSRVQLLRPGSLHKFIPEEIL 60
Query: 61 IHGRDFRLLRVGFEAGGLEPQAFQVTMAIVQARAQSNQAQQYSGITLSKAGQGSGSRKPP 120
IHGRDFRLLRVGFEAGGLEPQAFQVTMAIVQARAQSNQAQQYSGITLSKAGQGSGSRKPP
Sbjct: 61 IHGRDFRLLRVGFEAGGLEPQAFQVTMAIVQARAQSNQAQQYSGITLSKAGQGSGSRKPP 120
Query: 121 IPLMETAEDWETERKKQAARGWRVSTVNERFDVATSLPRYFWVPNRILDSEVRRAFGHFH 180
IPLMETAEDWETERKKQAARGWRVSTVNERFDVATSLPRYFWVPNRILDSEVRRAFGHFH
Sbjct: 121 IPLMETAEDWETERKKQAARGWRVSTVNERFDVATSLPRYFWVPNRILDSEVRRAFGHFH 180
Query: 181 QGRGPRLSWHHPGGSDLLRCGGFYTASDPNKEDIRAVELMLQAGHSDVVLVDTMDELPSL 240
QGRGPRLSWHHPGGSDLLRCGGFYTASDPNKEDIRAVELMLQAGHSDVVLVDTMDELPSL
Sbjct: 181 QGRGPRLSWHHPGGSDLLRCGGFYTASDPNKEDIRAVELMLQAGHSDVVLVDTMDELPSL 240
Query: 241 ADVQLAHLRLRALCLPDSSVAEDKWLSALEGTRWLDYVRACLRKASDISVLVTSRVRSVI 300
ADVQLAHLRLRALCLPDSSVAEDKWLSALEGTRWLDYVRACLRKASDISVLVTSRVRSVI
Sbjct: 241 ADVQLAHLRLRALCLPDSSVAEDKWLSALEGTRWLDYVRACLRKASDISVLVTSRVRSVI 300
Query: 301 LQERGDRDLNGLLSSLVQLLSAPEARTLFGFQSLVQREWVAAGHPFLTRLGGTGASEEAP 360
LQERGDRDLNGLLSSLVQLLSAPEARTLFGFQSLVQREWVAAGHPFLTRLGGTGASEEAP
Sbjct: 301 LQERGDRDLNGLLSSLVQLLSAPEARTLFGFQSLVQREWVAAGHPFLTRLGGTGASEEAP 360
Query: 361 VFLLFLDCVWQLLQQFPADFEFSEFFLLALHDSVRVPDTLTFLRNTPWERGKQSGQLNSY 420
VFLLFLDCVWQLLQQFPADFEFSEFFLLALHDSVRVPDTLTFLRNTPWERGKQSGQLNSY
Sbjct: 361 VFLLFLDCVWQLLQQFPADFEFSEFFLLALHDSVRVPDTLTFLRNTPWERGKQSGQLNSY 420
Query: 421 TQVYTPGYSQPPAGNSFNLQLSVWDWDLRYSNAQILQFQNPGYDPEHCPDSWLPRPQPSF 480
TQVYTPGYSQPPAGNSFNLQLSVWDWDLRYSNAQILQFQNPGYDPEHCPDSWLPRPQPSF
Sbjct: 421 TQVYTPGYSQPPAGNSFNLQLSVWDWDLRYSNAQILQFQNPGYDPEHCPDSWLPRPQPSF 480
Query: 481 MVPGPPSSVWLFSRGALTPLNQLCPWRDSPSLLAVSSRWLPRPAISSESLADQEWGLPSH 540
MVPGPPSSVWLFSRGALTPLNQLCPWRDSPSLLAVSSRWLPRPAISSESLADQEWGLPSH
Sbjct: 481 MVPGPPSSVWLFSRGALTPLNQLCPWRDSPSLLAVSSRWLPRPAISSESLADQEWGLPSH 540
Query: 541 WGACPLPPGLLLPGYLGPQIRLWRRCYLRGRPEVQMGLSAPTISGLQDELSHLQELLRKW 600
WGACPLPPGLLLPGYLGPQIRLWRRCYLRGRPEVQMGLSAPTISGLQDELSHLQELLRKW
Sbjct: 541 WGACPLPPGLLLPGYLGPQIRLWRRCYLRGRPEVQMGLSAPTISGLQDELSHLQELLRKW 600
Query: 601 TPRISPEDHSKKRDPHTILNPTEIAGILKGQSHPFWITRC 640
TPRISPEDHSKKRDPHTILNPTEIAGILKGQSHPFWITRC
Sbjct: 601 TPRISPEDHSKKRDPHTILNPTEIAGILKGQSHPFWITRC 640
>gi|224994251 myotubularin related protein 11 isoform a [Homo
sapiens]
Length = 709
Score = 1296 bits (3353), Expect = 0.0
Identities = 627/629 (99%), Positives = 629/629 (100%)
Query: 4 RVTFQPCGWQWNQDTPLNSEYDFALVNIGRLEAVSGLSRVQLLRPGSLHKFIPEEILIHG 63
RVTFQPCGWQWNQDTPLNSEYDFALVNIGRLEAVSGLSRVQLLRPGSLHKFIPEEILIHG
Sbjct: 76 RVTFQPCGWQWNQDTPLNSEYDFALVNIGRLEAVSGLSRVQLLRPGSLHKFIPEEILIHG 135
Query: 64 RDFRLLRVGFEAGGLEPQAFQVTMAIVQARAQSNQAQQYSGITLSKAGQGSGSRKPPIPL 123
RDFRLLRVGFEAGGLEPQAFQVTMAIVQARAQSNQAQQYSGITLSKAGQGSGSRKPPIPL
Sbjct: 136 RDFRLLRVGFEAGGLEPQAFQVTMAIVQARAQSNQAQQYSGITLSKAGQGSGSRKPPIPL 195
Query: 124 METAEDWETERKKQAARGWRVSTVNERFDVATSLPRYFWVPNRILDSEVRRAFGHFHQGR 183
METAEDWETERKKQAARGWRVSTVNERFDVATSLPRYFWVPNRILDSEVRRAFGHFHQGR
Sbjct: 196 METAEDWETERKKQAARGWRVSTVNERFDVATSLPRYFWVPNRILDSEVRRAFGHFHQGR 255
Query: 184 GPRLSWHHPGGSDLLRCGGFYTASDPNKEDIRAVELMLQAGHSDVVLVDTMDELPSLADV 243
GPRLSWHHPGGSDLLRCGGFYTASDPNKEDIRAVELMLQAGHSDVVLVDTMDELPSLADV
Sbjct: 256 GPRLSWHHPGGSDLLRCGGFYTASDPNKEDIRAVELMLQAGHSDVVLVDTMDELPSLADV 315
Query: 244 QLAHLRLRALCLPDSSVAEDKWLSALEGTRWLDYVRACLRKASDISVLVTSRVRSVILQE 303
QLAHLRLRALCLPDSSVAEDKWLSALEGTRWLDYVRACLRKASDISVLVTSRVRSVILQE
Sbjct: 316 QLAHLRLRALCLPDSSVAEDKWLSALEGTRWLDYVRACLRKASDISVLVTSRVRSVILQE 375
Query: 304 RGDRDLNGLLSSLVQLLSAPEARTLFGFQSLVQREWVAAGHPFLTRLGGTGASEEAPVFL 363
RGDRDLNGLLSSLVQLLSAPEARTLFGFQSLVQREWVAAGHPFLTRLGGTGASEEAPVFL
Sbjct: 376 RGDRDLNGLLSSLVQLLSAPEARTLFGFQSLVQREWVAAGHPFLTRLGGTGASEEAPVFL 435
Query: 364 LFLDCVWQLLQQFPADFEFSEFFLLALHDSVRVPDTLTFLRNTPWERGKQSGQLNSYTQV 423
LFLDCVWQLLQQFPADFEFSEFFLLALHDSVRVPDTLTFLRNTPWERGKQSGQLNSYTQV
Sbjct: 436 LFLDCVWQLLQQFPADFEFSEFFLLALHDSVRVPDTLTFLRNTPWERGKQSGQLNSYTQV 495
Query: 424 YTPGYSQPPAGNSFNLQLSVWDWDLRYSNAQILQFQNPGYDPEHCPDSWLPRPQPSFMVP 483
YTPGYSQPPAGNSFNLQLSVWDWDLRYSNAQILQFQNPGYDPEHCPDSWLPRPQPSFMVP
Sbjct: 496 YTPGYSQPPAGNSFNLQLSVWDWDLRYSNAQILQFQNPGYDPEHCPDSWLPRPQPSFMVP 555
Query: 484 GPPSSVWLFSRGALTPLNQLCPWRDSPSLLAVSSRWLPRPAISSESLADQEWGLPSHWGA 543
GPPSSVWLFSRGALTPLNQLCPWRDSPSLLAVSSRWLPRPAISSESLADQEWGLPSHWGA
Sbjct: 556 GPPSSVWLFSRGALTPLNQLCPWRDSPSLLAVSSRWLPRPAISSESLADQEWGLPSHWGA 615
Query: 544 CPLPPGLLLPGYLGPQIRLWRRCYLRGRPEVQMGLSAPTISGLQDELSHLQELLRKWTPR 603
CPLPPGLLLPGYLGPQIRLWRRCYLRGRPEVQMGLSAPTISGLQDELSHLQELLRKWTPR
Sbjct: 616 CPLPPGLLLPGYLGPQIRLWRRCYLRGRPEVQMGLSAPTISGLQDELSHLQELLRKWTPR 675
Query: 604 ISPEDHSKKRDPHTILNPTEIAGILKGQS 632
ISPEDHSKKRDPHTILNPTEIAGILKG++
Sbjct: 676 ISPEDHSKKRDPHTILNPTEIAGILKGRA 704
>gi|124028527 myotubularin related protein 10 [Homo sapiens]
Length = 777
Score = 294 bits (752), Expect = 2e-79
Identities = 213/624 (34%), Positives = 314/624 (50%), Gaps = 63/624 (10%)
Query: 20 LNSEYDFALVNIGRLEAVSGLSRVQ-LLRPGSLHKFIPEEILIHGRDFRLLRVGFEAGGL 78
L E+D L I ++ V+ R Q +L P KF P E++I+ +DFR++R F+ G
Sbjct: 94 LLGEHDVPLTCIEQIVTVNDHKRKQKVLGPNQKLKFNPTELIIYCKDFRIVRFRFDESGP 153
Query: 79 EPQAFQVTMAIVQ----------------ARAQSNQAQQYSGITLSKAGQGSGS------ 116
E A +V +AI + N A + +GI G G G
Sbjct: 154 E-SAKKVCLAIAHYSQPTDLQLLFAFEYVGKKYHNSANKINGIPSGDGGGGGGGGNGAGG 212
Query: 117 -RKPPIPLMETAEDWETERKKQAARGWRVSTVNERFDVATSLPRYFWVPNRILDSEVRRA 175
PL ET DW+ E K+ A GWRV ++NE + ++T LP Y VP+ + D +++
Sbjct: 213 GSSQKTPLFETYSDWDREIKRTGASGWRVCSINEGYMISTCLPEYIVVPSSLADQDLK-I 271
Query: 176 FGHFHQGRG-PRLSWHHPGGSDLLRCGGFYTASDPNKEDIRAVELMLQAG--HSDVVLVD 232
F H GR P W H GS L+R K D R + ++ SDV D
Sbjct: 272 FSHSFVGRRMPLWCWSHSNGSALVRMALIKDVLQQRKIDQRICNAITKSHPQRSDVYKSD 331
Query: 233 TMDELPSLADVQLAHLRLRALCLPDS-SVAEDKWLSALEGTRWLDYVRACLRKASDISVL 291
LP++ +VQ A ++L+ LC+ + E+KWLS+LE TRWL+YVRA L+ ++++ +
Sbjct: 332 LDKTLPNIQEVQAAFVKLKQLCVNEPFEETEEKWLSSLENTRWLEYVRAFLKHSAELVYM 391
Query: 292 VTSRVRSVILQERGDRDLNGLLSSLVQLLSAPEARTLFGFQSLVQREWVAAGHPFLTRLG 351
+ S+ SV+LQE RDL+ ++SLVQ++ P RT+ GFQSL+Q+EWV AG+ FL R
Sbjct: 392 LESKHLSVVLQEEEGRDLSCCVASLVQVMLDPYFRTITGFQSLIQKEWVMAGYQFLDRCN 451
Query: 352 GTGASE-EAPVFLLFLDCVWQLLQQFPADFEFSEFFLLALHDSVRVPDTLTFLRNTPWER 410
SE E+P+FLLFLD WQLL+Q+PA FEFSE +L L+DS R+ TFL N+P +R
Sbjct: 452 HLKRSEKESPLFLLFLDATWQLLEQYPAAFEFSETYLAVLYDSTRISLFGTFLFNSPHQR 511
Query: 411 GKQSGQLNSYTQVYTPGYSQPPAGNSFNLQL-SVWDWDLRYSNAQILQFQNPGYDPEHCP 469
KQS + + G+ L+ SVWDW L+++ F NP Y + P
Sbjct: 512 VKQSTEFAISKNI--------QLGDEKGLKFPSVWDWSLQFTAKDRTLFHNPFYIGKSTP 563
Query: 470 ------DSWLPRPQPSF--MVPGPPSSVWLFSRGALTPLNQLCPWRDSPSLLAVSSRWLP 521
R + S+ + G PS++ + + +L P R+S L + P
Sbjct: 564 CIQNGSVKSFKRTKKSYSSTLRGMPSAL----KNGIISDQELLPRRNSLIL-----KPKP 614
Query: 522 RPAISSESLADQEWGLPSHWGACPLP-PGLLLPGYLGPQIRLWRRCYLRGRPEVQMGLSA 580
PA ++S W + P G++LP G I+LW+ CY R PE Q+ L
Sbjct: 615 DPAQQTDSQNSDTEQYFREWFSKPANLHGVILPRVSGTHIKLWKLCYFRWVPEAQISLGG 674
Query: 581 P-----TISGLQDELSHLQELLRK 599
+S L DE+ L +LR+
Sbjct: 675 SITAFHKLSLLADEVDVLSRMLRQ 698
>gi|94721263 myotubularin related protein 12 [Homo sapiens]
Length = 747
Score = 209 bits (533), Expect = 5e-54
Identities = 176/603 (29%), Positives = 272/603 (45%), Gaps = 51/603 (8%)
Query: 49 GSLHKFIPEEILIHGRDFRLLRVGFEAGGLEPQAFQVTMAIVQARAQSNQAQQYSGITLS 108
G L K+ PE+++IH +D R+ + E + ++ I+ ++ + +
Sbjct: 130 GQLKKY-PEKLIIHCKDLRVFQFCLRYTK-EEEVKRIVSGIIHHTQAPKLLKRLFLFSYA 187
Query: 109 KAGQGSGSRKPP--IPLMETAEDW--ETERKKQAARGWRVSTVNERFDVATSLPRYFWVP 164
A Q + P + +T +DW E ER K + ++ +VNE + V LP YF VP
Sbjct: 188 TAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMK-YKAVSVNEGYKVCERLPAYFVVP 246
Query: 165 NRILDSEVRRAFGHFHQGRGPRLSWHHPGGSDLLRCGGFYTASDPNKEDIRAVEL----- 219
+ + V+R GH P W GS LL+ D I+ L
Sbjct: 247 TPLPEENVQRFQGHGI----PIWCWSCHNGSALLKMSALPKEQDDGILQIQKSFLDGIYK 302
Query: 220 -MLQAGHSDVVLVDTMDELPSLADVQLAHLRLRALCLPDSSV----AEDKWLSALEGTRW 274
+ + + V D SL ++Q A+ + + L L D+S + KW S LE + W
Sbjct: 303 TIHRPPYEIVKTEDLSSNFLSLQEIQTAYSKFKQLFLIDNSTEFWDTDIKWFSLLESSSW 362
Query: 275 LDYVRACLRKASDISVLVTSRVRSVILQERGDRDLNGLLSSLVQLLSAPEARTLFGFQSL 334
LD +R CL+KA +I+ + ++ +V+L E DL L+SSLVQL+ P RT GFQSL
Sbjct: 363 LDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPHCRTRIGFQSL 422
Query: 335 VQREWVAAGHPFLTRLG--GTGASEEAPVFLLFLDCVWQLLQQFPADFEFSEFFLLALHD 392
+Q+EWV GH FL R EE PVFLLFLDCVWQL+ Q P FEF+E +L L D
Sbjct: 423 IQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLDCVWQLVHQHPPAFEFTETYLTVLSD 482
Query: 393 SVRVPDTLTFLRNTPWERGKQSGQLNSYTQVYTPGYSQPPAGNSFNLQLSVWDWDLRYSN 452
S+ +P TF N+P ++ G+ TQ S+P NL L+VWDW +++
Sbjct: 483 SLYIPIFSTFFFNSPHQKDTNMGREGQDTQ------SKP-----LNL-LTVWDWSVQFEP 530
Query: 453 AQILQFQNPGYDPEHCPDSWLP-----RPQPSFMVPGPPSSVWLFSRGALTPLNQLCPWR 507
+NP Y + D + Q +P ++ +P
Sbjct: 531 KAQTLLKNPLYVEKPKLDKGQRKGMRFKHQRQLSLP--------LTQSKSSPKRGFFREE 582
Query: 508 DSPSLLAVSSRWLPRPAISSESLADQEWGLPSHWGACPLP-PGLLLPGYLGPQIRLWRRC 566
+ + + + + SS+ L D W + GLLLP GP+I++W +
Sbjct: 583 TDHLIKNLLGKRISKLINSSDELQDNFREFYDSWHSKSTDYHGLLLPHIEGPEIKVWAQR 642
Query: 567 YLRGRPEVQM--GLSAPTISGLQDELSHLQELLRKWTPRISPEDHSKKRDPHTILNPTEI 624
YLR PE Q+ G T+S L + + +Q L K R + + P + N +
Sbjct: 643 YLRWIPEAQILGGGQVATLSKLLEMMEEVQSLQEKIDERHHSQQAPQAEAPCLLRNSARL 702
Query: 625 AGI 627
+ +
Sbjct: 703 SSL 705
>gi|19923424 myotubularin related protein 9 [Homo sapiens]
Length = 549
Score = 150 bits (378), Expect = 5e-36
Identities = 108/335 (32%), Positives = 156/335 (46%), Gaps = 46/335 (13%)
Query: 122 PLMETAED-W-------ETERKKQAARGWRVSTVNERFDVATSLPRYFWVPNRILDSEVR 173
P+ E ED W E E A WR+S VN+ F V S P VP I D +R
Sbjct: 115 PMFEVIEDGWHSFLPEQEFELYSSATSEWRLSYVNKEFAVCPSYPPIVTVPKSIDDEALR 174
Query: 174 RAFGHFHQGRGPRLSWHHP-GGSDLLRCGGFYTASDPN--KEDIRAVELMLQAGHSDVVL 230
+ H GR P LS++H G ++R G T ++ KED + + L+AG +
Sbjct: 175 KVATFRHGGRFPVLSYYHKKNGMVIMRSGQPLTGTNGRRCKEDEKLINATLRAGKRGYI- 233
Query: 231 VDTMD----------------------------ELPSLADVQLAHLRLRALCLPDSSVAE 262
+DT + +Q + ++L C D +
Sbjct: 234 IDTRSLNVAQQTRAKGGGFEQEAHYPQWRRIHKSIERYHILQESLIKLVEAC-NDQTHNM 292
Query: 263 DKWLSALEGTRWLDYVRACLRKASDISVLVTSRVRSVILQERGDRDLNGLLSSLVQLLSA 322
D+WLS LE + WL +++ L A + + S+++ D ++SL Q++
Sbjct: 293 DRWLSKLEASNWLTHIKEILTTACLAAQCIDREGASILIHGTEGTDSTLQVTSLAQIILE 352
Query: 323 PEARTLFGFQSLVQREWVAAGHPFLTRLG-----GTGASEEAPVFLLFLDCVWQLLQQFP 377
P +RT+ GF++L++REW+ AGHPF R T EAPVFLLFLDCVWQ+L+QFP
Sbjct: 353 PRSRTIRGFEALIEREWLQAGHPFQQRCAQSAYCNTKQKWEAPVFLLFLDCVWQILRQFP 412
Query: 378 ADFEFSEFFLLALHDSVRVPDTLTFLRNTPWERGK 412
FEF+E FL+ L + TFL N ER K
Sbjct: 413 CSFEFNENFLIMLFEHAYASQFGTFLGNNESERCK 447
>gi|44680154 myotubularin-related protein 2 isoform 1 [Homo sapiens]
Length = 643
Score = 141 bits (355), Expect = 2e-33
Identities = 105/370 (28%), Positives = 171/370 (46%), Gaps = 64/370 (17%)
Query: 131 ETERKKQAARGWRVSTVNERFDVATSLPRYFWVPNRILDSEVRRAFGHFHQGRGPRLSWH 190
E R+ WR++ +NER+++ + P VP I D E++R +GR P LSW
Sbjct: 214 EYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSWI 273
Query: 191 HP-GGSDLLRCGG--FYTASDPNKEDIRAVELML--QAGHSDVVLVDTMDELPSLA---- 241
HP + + RC + +KED + ++ ++ A + + D + ++A
Sbjct: 274 HPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAVANKAK 333
Query: 242 ------------------DVQLAHL------RLRALCLPDSSVAEDKWLSALEGTRWLDY 277
D+ H+ +L+ + P ++ E WLS LE T WL++
Sbjct: 334 GGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYP--NIEETHWLSNLESTHWLEH 391
Query: 278 VRACLRKASDISVLVTSRVRSVILQERGDRDLNGLLSSLVQLLSAPEARTLFGFQSLVQR 337
++ L A I+ V S SV++ D L+SL L+ RT+ GF+ LV++
Sbjct: 392 IKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEK 451
Query: 338 EWVAAGHPFLTRLG----GTGASEEAPVFLLFLDCVWQLLQQFPADFEFSEFFLLALHDS 393
EW++ GH F R+G ++ +PVFL F+DCVWQ+ +QFP FEF+E+FL+ + D
Sbjct: 452 EWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDH 511
Query: 394 VRVPDTLTFLRNTPWERGKQSGQLNSYTQVYTPGYSQPPAGNSFNLQLSVWDWDLRYSNA 453
+ TFL N+ +RGK+ N +S+W Y N+
Sbjct: 512 LYSCLFGTFLCNSEQQRGKE---------------------NLPKRTVSLWS----YINS 546
Query: 454 QILQFQNPGY 463
Q+ F NP Y
Sbjct: 547 QLEDFTNPLY 556
>gi|41350318 myotubularin-related protein 2 isoform 2 [Homo sapiens]
Length = 571
Score = 141 bits (355), Expect = 2e-33
Identities = 105/370 (28%), Positives = 171/370 (46%), Gaps = 64/370 (17%)
Query: 131 ETERKKQAARGWRVSTVNERFDVATSLPRYFWVPNRILDSEVRRAFGHFHQGRGPRLSWH 190
E R+ WR++ +NER+++ + P VP I D E++R +GR P LSW
Sbjct: 142 EYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSWI 201
Query: 191 HP-GGSDLLRCGG--FYTASDPNKEDIRAVELML--QAGHSDVVLVDTMDELPSLA---- 241
HP + + RC + +KED + ++ ++ A + + D + ++A
Sbjct: 202 HPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAVANKAK 261
Query: 242 ------------------DVQLAHL------RLRALCLPDSSVAEDKWLSALEGTRWLDY 277
D+ H+ +L+ + P ++ E WLS LE T WL++
Sbjct: 262 GGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYP--NIEETHWLSNLESTHWLEH 319
Query: 278 VRACLRKASDISVLVTSRVRSVILQERGDRDLNGLLSSLVQLLSAPEARTLFGFQSLVQR 337
++ L A I+ V S SV++ D L+SL L+ RT+ GF+ LV++
Sbjct: 320 IKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEK 379
Query: 338 EWVAAGHPFLTRLG----GTGASEEAPVFLLFLDCVWQLLQQFPADFEFSEFFLLALHDS 393
EW++ GH F R+G ++ +PVFL F+DCVWQ+ +QFP FEF+E+FL+ + D
Sbjct: 380 EWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDH 439
Query: 394 VRVPDTLTFLRNTPWERGKQSGQLNSYTQVYTPGYSQPPAGNSFNLQLSVWDWDLRYSNA 453
+ TFL N+ +RGK+ N +S+W Y N+
Sbjct: 440 LYSCLFGTFLCNSEQQRGKE---------------------NLPKRTVSLWS----YINS 474
Query: 454 QILQFQNPGY 463
Q+ F NP Y
Sbjct: 475 QLEDFTNPLY 484
>gi|41350316 myotubularin-related protein 2 isoform 2 [Homo sapiens]
Length = 571
Score = 141 bits (355), Expect = 2e-33
Identities = 105/370 (28%), Positives = 171/370 (46%), Gaps = 64/370 (17%)
Query: 131 ETERKKQAARGWRVSTVNERFDVATSLPRYFWVPNRILDSEVRRAFGHFHQGRGPRLSWH 190
E R+ WR++ +NER+++ + P VP I D E++R +GR P LSW
Sbjct: 142 EYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSWI 201
Query: 191 HP-GGSDLLRCGG--FYTASDPNKEDIRAVELML--QAGHSDVVLVDTMDELPSLA---- 241
HP + + RC + +KED + ++ ++ A + + D + ++A
Sbjct: 202 HPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAVANKAK 261
Query: 242 ------------------DVQLAHL------RLRALCLPDSSVAEDKWLSALEGTRWLDY 277
D+ H+ +L+ + P ++ E WLS LE T WL++
Sbjct: 262 GGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYP--NIEETHWLSNLESTHWLEH 319
Query: 278 VRACLRKASDISVLVTSRVRSVILQERGDRDLNGLLSSLVQLLSAPEARTLFGFQSLVQR 337
++ L A I+ V S SV++ D L+SL L+ RT+ GF+ LV++
Sbjct: 320 IKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEK 379
Query: 338 EWVAAGHPFLTRLG----GTGASEEAPVFLLFLDCVWQLLQQFPADFEFSEFFLLALHDS 393
EW++ GH F R+G ++ +PVFL F+DCVWQ+ +QFP FEF+E+FL+ + D
Sbjct: 380 EWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDH 439
Query: 394 VRVPDTLTFLRNTPWERGKQSGQLNSYTQVYTPGYSQPPAGNSFNLQLSVWDWDLRYSNA 453
+ TFL N+ +RGK+ N +S+W Y N+
Sbjct: 440 LYSCLFGTFLCNSEQQRGKE---------------------NLPKRTVSLWS----YINS 474
Query: 454 QILQFQNPGY 463
Q+ F NP Y
Sbjct: 475 QLEDFTNPLY 484
>gi|28872761 myotubularin-related protein 1 [Homo sapiens]
Length = 665
Score = 137 bits (345), Expect = 3e-32
Identities = 104/370 (28%), Positives = 169/370 (45%), Gaps = 68/370 (18%)
Query: 131 ETERKKQAARGWRVSTVNERFDVATSLPRYFWVPNRILDSEVRRAFGHFHQGRGPRLSWH 190
E +R+ W++S +N ++ + P VP + D ++ + +GR P LSW
Sbjct: 235 EYKRQGLPNESWKISKINSNYEFCDTYPAIIVVPTSVKDDDLSKVAAFRAKGRVPVLSWI 294
Query: 191 HP-GGSDLLRCGGFYTASDPN----KEDIRAVELMLQAGHSDVVLVDTMDELPSLAD--- 242
HP + + RC PN KED + ++ ++ A L+ S+AD
Sbjct: 295 HPESQATITRCS--QPLVGPNDKRCKEDEKYLQTIMDANAQSHKLIIFDARQNSVADTNK 352
Query: 243 --------------VQLAHL-------------RLRALCLPDSSVAEDKWLSALEGTRWL 275
+L L +L+ + P S+ E +WLS ++GT WL
Sbjct: 353 TKGGGYESESAYPNAELVFLEIHNIHVMRESLRKLKEIVYP--SIDEARWLSNVDGTHWL 410
Query: 276 DYVRACLRKASDISVLVTSRVRSVILQERGDRDLNGLLSSLVQLLSAPEARTLFGFQSLV 335
+Y+R L A I+ + S SV++ D L+SL L+ RT+ GF++LV
Sbjct: 411 EYIRMLLAGAVRIADKIESGKTSVVVHCSDGWDRTAQLTSLAMLMLDSYYRTIKGFETLV 470
Query: 336 QREWVAAGHPFLTRLG----GTGASEEAPVFLLFLDCVWQLLQQFPADFEFSEFFLLALH 391
++EW++ GH F R+G ++ +P+FL F+DCVWQ+ +QFP+ FEF+E FL+ +
Sbjct: 471 EKEWISFGHRFALRVGHGNDNHADADRSPIFLQFVDCVWQMTRQFPSAFEFNELFLITIL 530
Query: 392 DSVRVPDTLTFLRNTPWERGKQSGQLNSYTQVYTPGYSQPPAGNSFNLQLSVWDWDLRYS 451
D + TFL N +R K+ VYT +S+W Y
Sbjct: 531 DHLYSCLFGTFLCNCEQQRFKE--------DVYTK-------------TISLWS----YI 565
Query: 452 NAQILQFQNP 461
N+Q+ +F NP
Sbjct: 566 NSQLDEFSNP 575
>gi|4557896 myotubularin [Homo sapiens]
Length = 603
Score = 127 bits (320), Expect = 2e-29
Identities = 87/307 (28%), Positives = 150/307 (48%), Gaps = 35/307 (11%)
Query: 142 WRVSTVNERFDVATSLPRYFWVPNRILDSEVRRAFGHFHQGRGPRLSWHHPGGSDLL-RC 200
WR++ +N+ +++ + P VP R D ++RR + R P LSW HP ++ RC
Sbjct: 183 WRITFINKCYELCDTYPALLVVPYRASDDDLRRVATFRSRNRIPVLSWIHPENKTVIVRC 242
Query: 201 GGFYT--ASDPNKEDIRAVELMLQAGH--SDVVLVDTMDELPSLA--------------- 241
+ NK+D + ++++ + S + + D + ++A
Sbjct: 243 SQPLVGMSGKRNKDDEKYLDVIRETNKQISKLTIYDARPSVNAVANKATGGGYESDDAYH 302
Query: 242 -------DVQLAHLRLRALC----LPDSSVAEDKWLSALEGTRWLDYVRACLRKASDISV 290
D+ H+ +L + +V E WLS+LE T WL++++ L A ++
Sbjct: 303 NAELFFLDIHNIHVMRESLKKVKDIVYPNVEESHWLSSLESTHWLEHIKLVLTGAIQVAD 362
Query: 291 LVTSRVRSVILQERGDRDLNGLLSSLVQLLSAPEARTLFGFQSLVQREWVAAGHPFLTRL 350
V+S SV++ D L+SL L+ R++ GF+ LVQ+EW++ GH F +R+
Sbjct: 363 KVSSGKSSVLVHCSDGWDRTAQLTSLAMLMLDSFYRSIEGFEILVQKEWISFGHKFASRI 422
Query: 351 G----GTGASEEAPVFLLFLDCVWQLLQQFPADFEFSEFFLLALHDSVRVPDTLTFLRNT 406
G ++ +P+FL F+DCVWQ+ +QFP FEF+E FL+ + D + TFL N
Sbjct: 423 GHGDKNHTDADRSPIFLQFIDCVWQMSKQFPTAFEFNEQFLIIILDHLYSCRFGTFLFNC 482
Query: 407 PWERGKQ 413
R +Q
Sbjct: 483 ESARERQ 489
>gi|21361759 myotubularin related protein 8 [Homo sapiens]
Length = 704
Score = 108 bits (269), Expect = 2e-23
Identities = 81/305 (26%), Positives = 137/305 (44%), Gaps = 35/305 (11%)
Query: 140 RGWRVSTVNERFDVATSLPRYFWVPNRILDSEVRRAFGHFHQGRGPRLSW-HHPGGSDLL 198
R W ++ N +++ ++ P VP + V + + R P LS+ + + +
Sbjct: 144 RNWTITDANRNYEICSTYPPEIVVPKSVTLGTVVGSSKFRSKERVPVLSYLYKENNAAIC 203
Query: 199 RCG----GFYTASDPNKEDIRAVELMLQAGHSDVVLVDTMDELPSLA----------DVQ 244
RC GFYT ++ + A+ G + +VDT +L ++A +
Sbjct: 204 RCSQPLSGFYTRCVDDELLLEAIS-QTNPGSQFMYVVDTRPKLNAMANRAAGKGYENEDN 262
Query: 245 LAHLRLRALCLPDSSVAED-----------------KWLSALEGTRWLDYVRACLRKASD 287
A++R R + + + V ++LS LE + WL +++A +
Sbjct: 263 YANIRFRFMGIENIHVMRSSLQKLLEVCELKTPTMSEFLSGLESSGWLRHIKAIMDAGIF 322
Query: 288 ISVLVTSRVRSVILQERGDRDLNGLLSSLVQLLSAPEARTLFGFQSLVQREWVAAGHPFL 347
I+ V SV++ D + S+ +L P RT G L+++EW++ GH F
Sbjct: 323 ITKAVKVEKASVLVHCSDGWDRTAQVCSVASILLDPFYRTFKGLMILIEKEWISMGHKFS 382
Query: 348 TRLGGTG--ASEEAPVFLLFLDCVWQLLQQFPADFEFSEFFLLALHDSVRVPDTLTFLRN 405
R G + E +P+F FLDC+WQL++QFP FEF+E FLL +HD V FL N
Sbjct: 383 QRCGHLDGDSKEVSPIFTQFLDCIWQLMEQFPCAFEFNENFLLEIHDHVFSCQFGNFLGN 442
Query: 406 TPWER 410
+R
Sbjct: 443 CQKDR 447
>gi|217272865 myotubularin related protein 4 [Homo sapiens]
Length = 1195
Score = 102 bits (254), Expect = 1e-21
Identities = 73/197 (37%), Positives = 100/197 (50%), Gaps = 24/197 (12%)
Query: 250 LRALC--LPDSSVAEDKWLSALEGTRWLDYVRACLRKASDISVLVTSRVRSVILQERGDR 307
LRA+C +PD S WLSALE T+WL ++ L+ A ++ V R V++
Sbjct: 356 LRAVCSQMPDPS----NWLSALESTKWLQHLSVMLKAAVLVANTVDREGRPVLVHCSDGW 411
Query: 308 DLNGLLSSLVQLLSAPEARTLFGFQSLVQREWVAAGHPFLTRLGG----TGASEEAPVFL 363
D + +L ++L P RTL GFQ LV+ +W+ GH F R G +E+ PVFL
Sbjct: 412 DRTPQIVALAKILLDPYYRTLEGFQVLVESDWLDFGHKFGDRCGHQENVEDQNEQCPVFL 471
Query: 364 LFLDCVWQLLQQFPADFEFSEFFLLALHDSVRVPDTLTFLRNTPWERGK----------- 412
+LD V QLL+QFP FEF+E FL+ L TFL N P ER K
Sbjct: 472 QWLDSVHQLLKQFPCLFEFNEAFLVKLVQHTYSCLYGTFLANNPCEREKRNIYKRTCSVW 531
Query: 413 ---QSGQLNSYTQVYTP 426
++G N + +YTP
Sbjct: 532 ALLRAGNKNFHNFLYTP 548
Score = 31.2 bits (69), Expect = 3.1
Identities = 18/60 (30%), Positives = 27/60 (45%), Gaps = 1/60 (1%)
Query: 142 WRVSTVNERFDVATSLPRYFWVPNRILDSEVRRAFGHFHQGRGPRLSWHH-PGGSDLLRC 200
WRVS +N + + S P+ VP I D E+ R P + + H G+ + RC
Sbjct: 174 WRVSHINSNYKLCPSYPQKLLVPVWITDKELENVASFRSWKRIPVVVYRHLRNGAAIARC 233
>gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens]
Length = 1161
Score = 102 bits (253), Expect = 1e-21
Identities = 89/269 (33%), Positives = 122/269 (45%), Gaps = 28/269 (10%)
Query: 237 LPSLADVQLAHLRLRALC--LPDSSVAEDKWLSALEGTRWLDYVRACLRKASDISVLVTS 294
+ ++ ++ + LR LC +PD WLSALE T+WL ++ L+ A + V
Sbjct: 349 MANIHSIRRSFQSLRLLCTQMPDPG----NWLSALESTKWLHHLSVLLKSALLVVHAVDQ 404
Query: 295 RVRSVILQERGDRDLNGLLSSLVQLLSAPEARTLFGFQSLVQREWVAAGHPFLTRLG--- 351
R V++ D + +L +LL P RT+ GFQ LV+ EW+ GH F R G
Sbjct: 405 DQRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLVEMEWLDFGHKFADRCGHGE 464
Query: 352 -GTGASEEAPVFLLFLDCVWQLLQQFPADFEFSEFFLLALHDSVRVPDTLTFLRNTPWER 410
+E PVFL +LDCV QL +QFP FEF+E FL+ L TFL N ER
Sbjct: 465 NSDDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCLFGTFLCNNAKER 524
Query: 411 GKQSGQLNSYTQVYTPGYSQPPAGNSF--NLQLSVWDWDLRYSNAQI--LQFQNPGYDPE 466
G++ Q + + +S AGN NL S + Y + L + Y P
Sbjct: 525 GEKHTQERTCSV-----WSLLRAGNKAFKNLLYSSQSEAVLYPVCHVRNLMLWSAVYLP- 578
Query: 467 HCP-------DSWLPRPQPSFMVPGPPSS 488
CP DS P P P PP S
Sbjct: 579 -CPSPTTPVDDSCAPYPAPGTSPDDPPLS 606
Score = 36.6 bits (83), Expect = 0.073
Identities = 19/61 (31%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Query: 142 WRVSTVNERFDVATSLPRYFWVPNRILDSEVRRAFGHFHQGRGPRLSW-HHPGGSDLLRC 200
WR+S +NE++ + S P+ VP I D E+ R P + + H G+ + RC
Sbjct: 176 WRISNINEKYKLCGSYPQELIVPAWITDKELESVSSFRSWKRIPAVIYRHQSNGAVIARC 235
Query: 201 G 201
G
Sbjct: 236 G 236
>gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens]
Length = 1170
Score = 102 bits (253), Expect = 1e-21
Identities = 89/269 (33%), Positives = 122/269 (45%), Gaps = 28/269 (10%)
Query: 237 LPSLADVQLAHLRLRALC--LPDSSVAEDKWLSALEGTRWLDYVRACLRKASDISVLVTS 294
+ ++ ++ + LR LC +PD WLSALE T+WL ++ L+ A + V
Sbjct: 349 MANIHSIRRSFQSLRLLCTQMPDPG----NWLSALESTKWLHHLSVLLKSALLVVHAVDQ 404
Query: 295 RVRSVILQERGDRDLNGLLSSLVQLLSAPEARTLFGFQSLVQREWVAAGHPFLTRLG--- 351
R V++ D + +L +LL P RT+ GFQ LV+ EW+ GH F R G
Sbjct: 405 DQRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLVEMEWLDFGHKFADRCGHGE 464
Query: 352 -GTGASEEAPVFLLFLDCVWQLLQQFPADFEFSEFFLLALHDSVRVPDTLTFLRNTPWER 410
+E PVFL +LDCV QL +QFP FEF+E FL+ L TFL N ER
Sbjct: 465 NSDDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCLFGTFLCNNAKER 524
Query: 411 GKQSGQLNSYTQVYTPGYSQPPAGNSF--NLQLSVWDWDLRYSNAQI--LQFQNPGYDPE 466
G++ Q + + +S AGN NL S + Y + L + Y P
Sbjct: 525 GEKHTQERTCSV-----WSLLRAGNKAFKNLLYSSQSEAVLYPVCHVRNLMLWSAVYLP- 578
Query: 467 HCP-------DSWLPRPQPSFMVPGPPSS 488
CP DS P P P PP S
Sbjct: 579 -CPSPTTPVDDSCAPYPAPGTSPDDPPLS 606
Score = 36.6 bits (83), Expect = 0.073
Identities = 19/61 (31%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Query: 142 WRVSTVNERFDVATSLPRYFWVPNRILDSEVRRAFGHFHQGRGPRLSW-HHPGGSDLLRC 200
WR+S +NE++ + S P+ VP I D E+ R P + + H G+ + RC
Sbjct: 176 WRISNINEKYKLCGSYPQELIVPAWITDKELESVSSFRSWKRIPAVIYRHQSNGAVIARC 235
Query: 201 G 201
G
Sbjct: 236 G 236
>gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens]
Length = 1198
Score = 102 bits (253), Expect = 1e-21
Identities = 89/269 (33%), Positives = 122/269 (45%), Gaps = 28/269 (10%)
Query: 237 LPSLADVQLAHLRLRALC--LPDSSVAEDKWLSALEGTRWLDYVRACLRKASDISVLVTS 294
+ ++ ++ + LR LC +PD WLSALE T+WL ++ L+ A + V
Sbjct: 349 MANIHSIRRSFQSLRLLCTQMPDPG----NWLSALESTKWLHHLSVLLKSALLVVHAVDQ 404
Query: 295 RVRSVILQERGDRDLNGLLSSLVQLLSAPEARTLFGFQSLVQREWVAAGHPFLTRLG--- 351
R V++ D + +L +LL P RT+ GFQ LV+ EW+ GH F R G
Sbjct: 405 DQRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLVEMEWLDFGHKFADRCGHGE 464
Query: 352 -GTGASEEAPVFLLFLDCVWQLLQQFPADFEFSEFFLLALHDSVRVPDTLTFLRNTPWER 410
+E PVFL +LDCV QL +QFP FEF+E FL+ L TFL N ER
Sbjct: 465 NSDDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCLFGTFLCNNAKER 524
Query: 411 GKQSGQLNSYTQVYTPGYSQPPAGNSF--NLQLSVWDWDLRYSNAQI--LQFQNPGYDPE 466
G++ Q + + +S AGN NL S + Y + L + Y P
Sbjct: 525 GEKHTQERTCSV-----WSLLRAGNKAFKNLLYSSQSEAVLYPVCHVRNLMLWSAVYLP- 578
Query: 467 HCP-------DSWLPRPQPSFMVPGPPSS 488
CP DS P P P PP S
Sbjct: 579 -CPSPTTPVDDSCAPYPAPGTSPDDPPLS 606
Score = 36.6 bits (83), Expect = 0.073
Identities = 19/61 (31%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Query: 142 WRVSTVNERFDVATSLPRYFWVPNRILDSEVRRAFGHFHQGRGPRLSW-HHPGGSDLLRC 200
WR+S +NE++ + S P+ VP I D E+ R P + + H G+ + RC
Sbjct: 176 WRISNINEKYKLCGSYPQELIVPAWITDKELESVSSFRSWKRIPAVIYRHQSNGAVIARC 235
Query: 201 G 201
G
Sbjct: 236 G 236
>gi|134142348 myotubularin related protein 6 [Homo sapiens]
Length = 621
Score = 99.4 bits (246), Expect = 9e-21
Identities = 87/334 (26%), Positives = 148/334 (44%), Gaps = 39/334 (11%)
Query: 112 QGSGSRKPPIPLMETAEDWETERKKQAARGWRVSTVNERFDVATSLPRYFWVPNRILDSE 171
Q R L++ AE+++ R W++S N + + + PR +VP RI
Sbjct: 116 QNDSERLQGWQLIDLAEEYK--RMGVPNSHWQLSDANRDYKICETYPRELYVP-RIASKP 172
Query: 172 VRRAFGHFH-QGRGPRLSWHHPGG-SDLLRCG----GFYTASDPNKEDIRAVELMLQAGH 225
+ F +GR P LS++H + + RC GF ++ ++A+
Sbjct: 173 IIVGSSKFRSKGRFPVLSYYHQDKEAAICRCSQPLSGFSARCLEDEHLLQAISKANPVNR 232
Query: 226 SDVVLVDTMDELPSLAD---------------VQLAHLRLRALCLPDSSVAE-------- 262
V+ DT +L ++A+ ++ + + + + SS+ +
Sbjct: 233 YMYVM-DTRPKLNAMANRAAGKGYENEDNYSNIRFQFVGIENIHVMRSSLQKLLEVNGTK 291
Query: 263 ----DKWLSALEGTRWLDYVRACLRKASDISVLVTSRVRSVILQERGDRDLNGLLSSLVQ 318
+ + S LE + WL +++A + A ++ +T SV++ D + SL
Sbjct: 292 GLSVNDFYSGLESSGWLRHIKAVMDAAIFLAKAITVENASVLVHCSDGWDRTSQVCSLGS 351
Query: 319 LLSAPEARTLFGFQSLVQREWVAAGHPFLTRLGGTGAS--EEAPVFLLFLDCVWQLLQQF 376
LL RT+ GF L++++W++ GH F R G E +PVF FL+CVW L +QF
Sbjct: 352 LLLDSYYRTIKGFMVLIEKDWISFGHKFSERCGQLDGDPKEVSPVFTQFLECVWHLTEQF 411
Query: 377 PADFEFSEFFLLALHDSVRVPDTLTFLRNTPWER 410
P FEFSE FLL +H+ + FL N ER
Sbjct: 412 PQAFEFSEAFLLQIHEHIHSCQFGNFLGNCQKER 445
>gi|225543474 myotubularin related protein 7 [Homo sapiens]
Length = 660
Score = 94.0 bits (232), Expect = 4e-19
Identities = 81/316 (25%), Positives = 141/316 (44%), Gaps = 39/316 (12%)
Query: 142 WRVSTVNERFDVATSLPRYFWVPNRILDSEVRRAFGHFHQGRGPRLSWHHPGG-SDLLRC 200
W++S VN + V S P +VP + + + R P LS+++ + + R
Sbjct: 146 WQLSDVNRDYRVCDSYPTELYVPKSATAHIIVGSSKFRSRRRFPVLSYYYKDNHASICRS 205
Query: 201 G----GFYTASDPNKEDIRAVELMLQAGHSDVVLVDTMDELPSLAD-------------- 242
GF +++ ++A+ G V +VDT +L ++A+
Sbjct: 206 SQPLSGFSARCLEDEQMLQAIR-KANPGSDFVYVVDTRPKLNAMANRAAGKGYENEDNYS 264
Query: 243 --------VQLAHLRLRAL------C-LPDSSVAEDKWLSALEGTRWLDYVRACLRKASD 287
++ H+ +L C L S+++ W LE + WL +++A +
Sbjct: 265 NIKFQFIGIENIHVMRNSLQKMLEVCELKSPSMSDFLW--GLENSGWLRHIKAIMDAGIF 322
Query: 288 ISVLVTSRVRSVILQERGDRDLNGLLSSLVQLLSAPEARTLFGFQSLVQREWVAAGHPFL 347
I+ V+ SV++ D + S+ LL P RTL GF L++++W++ GH F
Sbjct: 323 IAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLLDPHYRTLKGFMVLIEKDWISFGHKFN 382
Query: 348 TRLGGTGA--SEEAPVFLLFLDCVWQLLQQFPADFEFSEFFLLALHDSVRVPDTLTFLRN 405
R G E +PV F++CVWQL++QFP FEF+E FL+ + + FL N
Sbjct: 383 HRYGNLDGDPKEISPVIDQFIECVWQLMEQFPCAFEFNERFLIHIQHHIYSCQFGNFLCN 442
Query: 406 TPWERGKQSGQLNSYT 421
+ ER + Q +Y+
Sbjct: 443 SQKERRELKIQERTYS 458
>gi|239735519 SET binding factor 1 [Homo sapiens]
Length = 1893
Score = 92.8 bits (229), Expect = 9e-19
Identities = 70/180 (38%), Positives = 99/180 (55%), Gaps = 19/180 (10%)
Query: 243 VQLAHLRLRALCLPDSSVAEDK---WLSALEGTRWLDYVRACLRKASDISVLVTSRV--- 296
V+ + +L C+P AE +L +LE + WL + L+ +SVLV +
Sbjct: 1385 VKASFKKLLKACVPGCPAAEPSPASFLRSLEDSEWLIQIHKLLQ----VSVLVVELLDSG 1440
Query: 297 RSVILQERGDRDLNGLLSSLVQLLSAPEARTLFGFQSLVQREWVAAGHPFLTRLGGTGAS 356
SV++ D+ + SLVQLLS P RTL GF+ LV++EW++ GH F R T A
Sbjct: 1441 SSVLVGLEDGWDITTQVVSLVQLLSDPFYRTLEGFRLLVEKEWLSFGHRFSHRGAHTLAG 1500
Query: 357 EEA---PVFLLFLDCVWQLLQQFPADFEFSEFFLLAL---HDSVRVPDTLTFLRNTPWER 410
+ + PVFL FLDCV Q+ QFP +FEFS+F+L L H S R TFL ++ +ER
Sbjct: 1501 QSSGFTPVFLQFLDCVHQVHLQFPMEFEFSQFYLKFLGYHHVSRRF---RTFLLDSDYER 1557
Score = 34.3 bits (77), Expect = 0.36
Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
Query: 142 WRVSTVNERFDVATSLPRYFWVPNRILDSEVRRAFGHFHQGRGPRLSWHH-PGGSDLLRC 200
+R+S VN + + S P VP + D+ ++R + Q R P + W + LLR
Sbjct: 1150 FRISPVNRMYAICRSYPGLLIVPQSVQDNALQRVSRCYRQNRFPVVCWRSGRSKAVLLRS 1209
Query: 201 GGFY 204
GG +
Sbjct: 1210 GGLH 1213
>gi|29788755 SET binding factor 2 [Homo sapiens]
Length = 1849
Score = 92.0 bits (227), Expect = 1e-18
Identities = 62/180 (34%), Positives = 97/180 (53%), Gaps = 6/180 (3%)
Query: 236 ELPSLADVQLAHLRLRALCLPDS--SVAEDKWLSALEGTRWLDYVRACLRKASDISVLVT 293
E + V+ + +L C+P + + +E +L AL + W + ++ A +S ++
Sbjct: 1342 EFHEIRQVKASFKKLMRACIPSTIPTDSEVTFLKALGDSEWFPQLHRIMQLAVVVSEVLE 1401
Query: 294 SRVRSVILQERGDRDLNGLLSSLVQLLSAPEARTLFGFQSLVQREWVAAGHPFLTRLGGT 353
+ ++ E G D+ ++SLVQLLS P RTL GFQ LV++EW++ GH F R T
Sbjct: 1402 NGSSVLVCLEEG-WDITAQVTSLVQLLSDPFYRTLEGFQMLVEKEWLSFGHKFSQRSSLT 1460
Query: 354 ---GASEEAPVFLLFLDCVWQLLQQFPADFEFSEFFLLALHDSVRVPDTLTFLRNTPWER 410
S APVFL FLDCV Q+ Q+P +FEF+ ++L L TFL ++ +ER
Sbjct: 1461 LNCQGSGFAPVFLQFLDCVHQVHNQYPTEFEFNLYYLKFLAFHYVSNRFKTFLLDSDYER 1520
Score = 35.0 bits (79), Expect = 0.21
Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
Query: 142 WRVSTVNERFDVATSLPRYFWVPNRILDSEVRRAFGHFHQGRGPRLSWHHP-GGSDLLRC 200
+R++ N + + S P VP + DS + R + R P + W + G+ LLR
Sbjct: 1138 FRITASNRMYSLCRSYPGLLVVPQAVQDSSLPRVARCYRHNRLPVVCWKNSRSGTLLLRS 1197
Query: 201 GGFY 204
GGF+
Sbjct: 1198 GGFH 1201
>gi|239756935 PREDICTED: hypothetical protein XP_002345110 [Homo
sapiens]
Length = 237
Score = 35.8 bits (81), Expect = 0.12
Identities = 46/168 (27%), Positives = 62/168 (36%), Gaps = 27/168 (16%)
Query: 410 RGKQSGQLNSYTQVYTPGY----------SQPPAGNSFNLQLSVWDWDLRYSNAQILQFQ 459
RG+Q+G L Q Y PG P A N F L LS Q
Sbjct: 73 RGRQNGGLPRSEQPYRPGRWREGWRSCSGDLPSAWNWFLLCLSACGCPSALVTPQAPAVP 132
Query: 460 NPGY--DPEHC-PDSW-LPRPQPSFMVPGPPSSVWLFSRGALTPLNQLCPWRDSPSLLAV 515
+PGY P C P W P+P + G + L + + CP DS
Sbjct: 133 SPGYVPAPSFCHPHQWAASEPRPFWGYRGGCTRSMLCTEEQAVGADATCP-ADS------ 185
Query: 516 SSRWLPRPAISSESLADQEWG------LPSHWGACPLPPGLLLPGYLG 557
SS PA+ +++ +WG P+H A PLP +L + G
Sbjct: 186 SSPSKADPALGERGVSEVDWGEAAPSPTPAHSMAHPLPARVLGSAFHG 233
>gi|239751447 PREDICTED: hypothetical protein XP_002347851 [Homo
sapiens]
Length = 237
Score = 35.8 bits (81), Expect = 0.12
Identities = 46/168 (27%), Positives = 62/168 (36%), Gaps = 27/168 (16%)
Query: 410 RGKQSGQLNSYTQVYTPGY----------SQPPAGNSFNLQLSVWDWDLRYSNAQILQFQ 459
RG+Q+G L Q Y PG P A N F L LS Q
Sbjct: 73 RGRQNGGLPRSEQPYRPGRWREGWRSCSGDLPSAWNWFLLCLSACGCPSALVTPQAPAVP 132
Query: 460 NPGY--DPEHC-PDSW-LPRPQPSFMVPGPPSSVWLFSRGALTPLNQLCPWRDSPSLLAV 515
+PGY P C P W P+P + G + L + + CP DS
Sbjct: 133 SPGYVPAPSFCHPHQWAASEPRPFWGYRGGCTRSMLCTEEQAVGADATCP-ADS------ 185
Query: 516 SSRWLPRPAISSESLADQEWG------LPSHWGACPLPPGLLLPGYLG 557
SS PA+ +++ +WG P+H A PLP +L + G
Sbjct: 186 SSPSKADPALGERGVSEVDWGEAAPSPTPAHSMAHPLPARVLGSAFHG 233
>gi|239745952 PREDICTED: hypothetical protein XP_002343584 [Homo
sapiens]
Length = 237
Score = 35.0 bits (79), Expect = 0.21
Identities = 46/168 (27%), Positives = 61/168 (36%), Gaps = 27/168 (16%)
Query: 410 RGKQSGQLNSYTQVYTPGY----------SQPPAGNSFNLQLSVWDWDLRYSNAQILQFQ 459
RG+Q+G L Q Y PG P A N F L LS Q
Sbjct: 73 RGRQNGGLPRSEQPYRPGRWREGWRSCSGDLPSAWNWFLLCLSACGCPSALVTPQAPAVP 132
Query: 460 NPGY--DPEHC-PDSW-LPRPQPSFMVPGPPSSVWLFSRGALTPLNQLCPWRDSPSLLAV 515
+PGY P C P W P+P + G + L + + CP DS
Sbjct: 133 SPGYVPAPSFCHPHQWAASEPRPFWGYRGGCTRSMLCTEEQAVGADATCP-ADS------ 185
Query: 516 SSRWLPRPAISSESLADQEWG------LPSHWGACPLPPGLLLPGYLG 557
SS PA+ +++ +WG P+H A PLP L + G
Sbjct: 186 SSPSKADPALGERGVSEVDWGEAAPSPTPAHSMAHPLPARALGSAFHG 233
>gi|195963410 MEF2 activating motif and SAP domain containing
transcriptional regulator isoform 1 [Homo sapiens]
Length = 415
Score = 32.3 bits (72), Expect = 1.4
Identities = 22/58 (37%), Positives = 28/58 (48%), Gaps = 11/58 (18%)
Query: 469 PDSWLPRPQPSFMVPGPPSSV--WLFSRGALTPLNQLC-PWR----DSPSLLAVSSRW 519
PD W+ P + P PS +LFS G L P + C PWR +SP +S RW
Sbjct: 36 PDPWISASDPP-LAPALPSGTAPFLFSPGVLLPEPEYCPPWRSPKKESPK---ISQRW 89
>gi|239752306 PREDICTED: hypothetical protein XP_002348194 [Homo
sapiens]
Length = 160
Score = 32.0 bits (71), Expect = 1.8
Identities = 23/77 (29%), Positives = 28/77 (36%), Gaps = 7/77 (9%)
Query: 469 PDSWLPRPQPSFMV---PGPPSSVWLFSRGALTPLNQLCPWRDSPSLLAVSSRWLPRPAI 525
P +W P P P V PGPPS + L C W S + + W P
Sbjct: 30 PGAWRPEPLPDPGVRSGPGPPSRLGLSGSSRSRGFRPFCGWEIS----GLEAAWPPACPA 85
Query: 526 SSESLADQEWGLPSHWG 542
S + A G PS G
Sbjct: 86 VSITTAGSRAGTPSCGG 102
>gi|239746817 PREDICTED: hypothetical protein XP_002343856 [Homo
sapiens]
Length = 160
Score = 32.0 bits (71), Expect = 1.8
Identities = 23/77 (29%), Positives = 28/77 (36%), Gaps = 7/77 (9%)
Query: 469 PDSWLPRPQPSFMV---PGPPSSVWLFSRGALTPLNQLCPWRDSPSLLAVSSRWLPRPAI 525
P +W P P P V PGPPS + L C W S + + W P
Sbjct: 30 PGAWRPEPLPDPGVRSGPGPPSRLGLSGSSRSRGFRPFCGWEIS----GLEAAWPPACPA 85
Query: 526 SSESLADQEWGLPSHWG 542
S + A G PS G
Sbjct: 86 VSITTAGSRAGTPSCGG 102
>gi|38424083 short-chain dehydrogenase/reductase 10 isoform d [Homo
sapiens]
Length = 152
Score = 31.6 bits (70), Expect = 2.3
Identities = 16/41 (39%), Positives = 21/41 (51%), Gaps = 2/41 (4%)
Query: 483 PGPPSSVWLFSRGALTPLNQLCPWRDSPSLLAVSSRWLPRP 523
PGP +++ + GA PWR LL + RWLPRP
Sbjct: 98 PGPKAALAVIRGGATRAAGVFYPWRFR--LLCLLRRWLPRP 136
>gi|38424075 short-chain dehydrogenase/reductase 10 isoform a [Homo
sapiens]
Length = 205
Score = 31.6 bits (70), Expect = 2.3
Identities = 16/41 (39%), Positives = 21/41 (51%), Gaps = 2/41 (4%)
Query: 483 PGPPSSVWLFSRGALTPLNQLCPWRDSPSLLAVSSRWLPRP 523
PGP +++ + GA PWR LL + RWLPRP
Sbjct: 151 PGPKAALAVIRGGATRAAGVFYPWRFR--LLCLLRRWLPRP 189
>gi|38424079 short-chain dehydrogenase/reductase 10 isoform c [Homo
sapiens]
Length = 199
Score = 31.6 bits (70), Expect = 2.3
Identities = 16/41 (39%), Positives = 21/41 (51%), Gaps = 2/41 (4%)
Query: 483 PGPPSSVWLFSRGALTPLNQLCPWRDSPSLLAVSSRWLPRP 523
PGP +++ + GA PWR LL + RWLPRP
Sbjct: 145 PGPKAALAVIRGGATRAAGVFYPWRFR--LLCLLRRWLPRP 183
>gi|38424085 short-chain dehydrogenase/reductase 10 isoform b [Homo
sapiens]
Length = 286
Score = 31.6 bits (70), Expect = 2.3
Identities = 16/41 (39%), Positives = 21/41 (51%), Gaps = 2/41 (4%)
Query: 483 PGPPSSVWLFSRGALTPLNQLCPWRDSPSLLAVSSRWLPRP 523
PGP +++ + GA PWR LL + RWLPRP
Sbjct: 232 PGPKAALAVIRGGATRAAGVFYPWRFR--LLCLLRRWLPRP 270
>gi|169173184 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1230
Score = 31.2 bits (69), Expect = 3.1
Identities = 32/102 (31%), Positives = 39/102 (38%), Gaps = 26/102 (25%)
Query: 498 TPLNQLCPWRDSPSLLAVSS-------RWLPRPAISSESLADQE-----WGLPSHWGACP 545
TPL CPW P L SS WL + + L + W +PS C
Sbjct: 879 TPLASSCPWGPPPLLKVFSSDSPRDPAPWLALLLLDAPELGPGDGVGPGWRVPS----CG 934
Query: 546 LPPG------LLLPGYLGPQIRLWRRCYLRGRPEVQMGLSAP 581
LPPG LLP + RLW +GRP +G P
Sbjct: 935 LPPGPRAVLWWLLPVLPQLEERLWG----QGRPLGGVGQYLP 972
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.442
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,488,827
Number of Sequences: 37866
Number of extensions: 1443150
Number of successful extensions: 3739
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 3660
Number of HSP's gapped (non-prelim): 77
length of query: 640
length of database: 18,247,518
effective HSP length: 109
effective length of query: 531
effective length of database: 14,120,124
effective search space: 7497785844
effective search space used: 7497785844
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.