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Search of human proteins with 88758613
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|88758613 CD93 antigen precursor [Homo sapiens]
(652 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|88758613 CD93 antigen precursor [Homo sapiens] 1386 0.0
gi|9966885 tumor endothelial marker 1 precursor [Homo sapiens] 201 2e-51
gi|4507483 thrombomodulin precursor [Homo sapiens] 198 1e-50
gi|34734064 fibulin 1 isoform B precursor [Homo sapiens] 151 2e-36
gi|34734068 fibulin 1 isoform A precursor [Homo sapiens] 151 2e-36
gi|34734066 fibulin 1 isoform D [Homo sapiens] 151 2e-36
gi|34734062 fibulin 1 isoform C precursor [Homo sapiens] 151 2e-36
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 146 5e-35
gi|24430141 fibrillin 1 precursor [Homo sapiens] 143 4e-34
gi|114431244 von Willebrand factor C and EGF domains [Homo sapiens] 142 7e-34
gi|46249414 latent transforming growth factor beta binding prote... 140 3e-33
gi|46249412 latent transforming growth factor beta binding prote... 140 3e-33
gi|66346695 fibrillin 2 precursor [Homo sapiens] 138 2e-32
gi|31377568 signal peptide, CUB domain, EGF-like 3 [Homo sapiens] 138 2e-32
gi|194328809 latent transforming growth factor beta binding prot... 137 3e-32
gi|18497288 latent transforming growth factor beta binding prote... 137 3e-32
gi|110347437 latent transforming growth factor beta binding prot... 137 4e-32
gi|110347412 latent transforming growth factor beta binding prot... 137 4e-32
gi|110347431 latent transforming growth factor beta binding prot... 137 4e-32
gi|19743803 fibulin 5 precursor [Homo sapiens] 134 3e-31
gi|56237021 fibrillin 3 precursor [Homo sapiens] 130 4e-30
gi|190343004 EGF-containing fibulin-like extracellular matrix pr... 130 5e-30
gi|10190748 CEGP1 protein [Homo sapiens] 128 1e-29
gi|4557733 latent transforming growth factor beta binding protei... 128 2e-29
gi|51873055 fibulin 2 isoform b precursor [Homo sapiens] 127 3e-29
gi|51873053 fibulin 2 isoform a precursor [Homo sapiens] 127 3e-29
gi|120587029 signal peptide, CUB domain, EGF-like 1 [Homo sapiens] 126 7e-29
gi|62548862 matrilin 2 isoform b precursor [Homo sapiens] 125 1e-28
gi|62548860 matrilin 2 isoform a precursor [Homo sapiens] 125 1e-28
gi|118572606 hemicentin 1 [Homo sapiens] 124 3e-28
>gi|88758613 CD93 antigen precursor [Homo sapiens]
Length = 652
Score = 1386 bits (3588), Expect = 0.0
Identities = 652/652 (100%), Positives = 652/652 (100%)
Query: 1 MATSMGLLLLLLLLLTQPGAGTGADTEAVVCVGTACYTAHSGKLSAAEAQNHCNQNGGNL 60
MATSMGLLLLLLLLLTQPGAGTGADTEAVVCVGTACYTAHSGKLSAAEAQNHCNQNGGNL
Sbjct: 1 MATSMGLLLLLLLLLTQPGAGTGADTEAVVCVGTACYTAHSGKLSAAEAQNHCNQNGGNL 60
Query: 61 ATVKSKEEAQHVQRVLAQLLRREAALTARMSKFWIGLQREKGKCLDPSLPLKGFSWVGGG 120
ATVKSKEEAQHVQRVLAQLLRREAALTARMSKFWIGLQREKGKCLDPSLPLKGFSWVGGG
Sbjct: 61 ATVKSKEEAQHVQRVLAQLLRREAALTARMSKFWIGLQREKGKCLDPSLPLKGFSWVGGG 120
Query: 121 EDTPYSNWHKELRNSCISKRCVSLLLDLSQPLLPSRLPKWSEGPCGSPGSPGSNIEGFVC 180
EDTPYSNWHKELRNSCISKRCVSLLLDLSQPLLPSRLPKWSEGPCGSPGSPGSNIEGFVC
Sbjct: 121 EDTPYSNWHKELRNSCISKRCVSLLLDLSQPLLPSRLPKWSEGPCGSPGSPGSNIEGFVC 180
Query: 181 KFSFKGMCRPLALGGPGQVTYTTPFQTTSSSLEAVPFASAANVACGEGDKDETQSHYFLC 240
KFSFKGMCRPLALGGPGQVTYTTPFQTTSSSLEAVPFASAANVACGEGDKDETQSHYFLC
Sbjct: 181 KFSFKGMCRPLALGGPGQVTYTTPFQTTSSSLEAVPFASAANVACGEGDKDETQSHYFLC 240
Query: 241 KEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTC 300
KEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTC
Sbjct: 241 KEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTC 300
Query: 301 ASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQECVN 360
ASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQECVN
Sbjct: 301 ASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQECVN 360
Query: 361 TPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGE 420
TPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGE
Sbjct: 361 TPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGE 420
Query: 421 DGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSCTMGPVSLGPPSGP 480
DGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSCTMGPVSLGPPSGP
Sbjct: 421 DGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSCTMGPVSLGPPSGP 480
Query: 481 PDEEDKGEKEGSTVPRAATASPTRGPEGTPKATPTTSRPSLSSDAPITSAPLKMLAPSGS 540
PDEEDKGEKEGSTVPRAATASPTRGPEGTPKATPTTSRPSLSSDAPITSAPLKMLAPSGS
Sbjct: 481 PDEEDKGEKEGSTVPRAATASPTRGPEGTPKATPTTSRPSLSSDAPITSAPLKMLAPSGS 540
Query: 541 PGVWREPSIHHATAASGPQEPAGGDSSVATQNNDGTDGQKLLLFYILGTVVAILLLLALA 600
PGVWREPSIHHATAASGPQEPAGGDSSVATQNNDGTDGQKLLLFYILGTVVAILLLLALA
Sbjct: 541 PGVWREPSIHHATAASGPQEPAGGDSSVATQNNDGTDGQKLLLFYILGTVVAILLLLALA 600
Query: 601 LGLLVYRKRRAKREEKKEKKPQNAADSYSWVPERAESRAMENQYSPTPGTDC 652
LGLLVYRKRRAKREEKKEKKPQNAADSYSWVPERAESRAMENQYSPTPGTDC
Sbjct: 601 LGLLVYRKRRAKREEKKEKKPQNAADSYSWVPERAESRAMENQYSPTPGTDC 652
>gi|9966885 tumor endothelial marker 1 precursor [Homo sapiens]
Length = 757
Score = 201 bits (510), Expect = 2e-51
Identities = 137/401 (34%), Positives = 189/401 (47%), Gaps = 54/401 (13%)
Query: 7 LLLLLLLLLTQPGAGTGADTEAV----VCVGTACYTAHSGKLSAAEAQNHCNQNGGNLAT 62
+LL LLL G G D A C ++CY + + EA C + GG+LAT
Sbjct: 1 MLLRLLLAWAAAGPTLGQDPWAAEPRAACGPSSCYALFPRRRTFLEAWRACRELGGDLAT 60
Query: 63 VKSKEEAQHVQRVLAQLLRREAALTARMSKFWIGLQREKGKCLDPSLPLKGFSWVGGGED 122
++ EEAQ V ++ A +R+ WIGLQR+ +C PL+GF+W G +D
Sbjct: 61 PRTPEEAQRVDSLVG------AGPASRL--LWIGLQRQARQC-QLQRPLRGFTWTTGDQD 111
Query: 123 TPYSNWHKELRNS-CISKRCVSLLLDLSQPLLPSRLPKWSEGPCGSPGSPGSNIEGFVCK 181
T ++NW + C ++RCV+L S +W EG C ++G++C+
Sbjct: 112 TAFTNWAQPASGGPCPAQRCVALEA--------SGEHRWLEGSCTLA------VDGYLCQ 157
Query: 182 FSFKGMCRPLA--LGGPGQVTYTTPFQTTSSSLEAVPFASAANVACGEGDKDETQSHYFL 239
F F+G C L G G YTTPF S+ E +PF S A V C G + L
Sbjct: 158 FGFEGACPALQDEAGQAGPAVYTTPFHLVSTEFEWLPFGSVAAVQCQAG-----RGASLL 212
Query: 240 CKEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVT 299
C ++ W +GPLC+ GC+ +NGGC +C E DG C C GFRL D +
Sbjct: 213 CVKQPEGGVGWSRAGPLCLGT--GCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRS 270
Query: 300 CASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQ-LDSSQLDCVDVDECQ-DSPCAQE 357
C +PC+ +PC GP G Y+C C G++ + CVD DECQ C Q
Sbjct: 271 C--EDPCAQAPCEQQCE-PGGPQG--YSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQM 325
Query: 358 CVNTPGGFRCECWVGYE----------PGGPGEGACQDVDE 388
CVN GGF C C G+E G G A QD+ +
Sbjct: 326 CVNYVGGFECYCSEGHELEADGISCSPAGAMGAQASQDLGD 366
>gi|4507483 thrombomodulin precursor [Homo sapiens]
Length = 575
Score = 198 bits (503), Expect = 1e-50
Identities = 172/557 (30%), Positives = 233/557 (41%), Gaps = 103/557 (18%)
Query: 5 MGLLLLLLLLLTQPGAGTGADTE--AVVCVGTACYTAHSGKLSAAEAQNHCNQNGGNLAT 62
+G+L+L L L G A+ + CV C+ + G + A C+ G+L T
Sbjct: 2 LGVLVLGALALAGLGFPAPAEPQPGGSQCVEHDCFALYPGPATFLNASQICDGLRGHLMT 61
Query: 63 VKSKEEAQHVQRVLAQLLRREAALTARMSKFWIGLQREKGKCLDPSL--PLKGFSWVGGG 120
V+S A V++ LL + + R + WIGLQ G C DP PL+GF WV G
Sbjct: 62 VRSSVAAD----VISLLLNGDGGVGRR--RLWIGLQLPPG-CGDPKRLGPLRGFQWVTGD 114
Query: 121 EDTPYSNWHKELRNSCISKRCVSLLLDLSQPLLPSRLPKWSEGPCGSPGSPGSNIEGFVC 180
+T YS W + N + + + ++ +PS P W E C +GF+C
Sbjct: 115 NNTSYSRWARLDLNGAPLCGPLCVAVSAAEATVPSE-PIWEEQQCEVKA------DGFLC 167
Query: 181 KFSFKGMCRPLALGGPG------QVTYTTPFQTTSSSLEAVPFASAANVA-------CGE 227
+F F CRPLA+ PG +TY TPF + +A+P S+A VA C
Sbjct: 168 EFHFPATCRPLAVE-PGAAAAAVSITYGTPFAARGADFQALPVGSSAAVAPLGLQLMC-T 225
Query: 228 GDKDETQSHYFLCKEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGC 287
Q H+ +AP +D C+ NGGC C G+ C C
Sbjct: 226 APPGAVQGHW---AREAPGAWD--------------CSVENGGCEHAC-NAIPGAPRCQC 267
Query: 288 RPGFRLLDDLVTC-ASRNPCSSSPCRGGATCVLGPHGK-NYTCRCPQGYQLDSSQLDCVD 345
G L D +C AS + C CV P +Y+C C GY+L + Q C D
Sbjct: 268 PAGAALQADGRSCTASATQSCNDLCEH--FCVPNPDQPGSYSCMCETGYRLAADQHRCED 325
Query: 346 VDEC--QDSPCAQECVNTPGGFRCECWVGY--------EPGGP-----GEGACQDVDE-- 388
VD+C + SPC Q CVNT GGF C C+ Y EP P E CQ +++
Sbjct: 326 VDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDGECVEPVDPCFRANCEYQCQPLNQTS 385
Query: 389 ----CALGRSP-------CAQGCTNT--------DGSFHCSCEEGYVLAGEDGTQCQDVD 429
CA G +P C C T + C C EGY+L +DG C D+D
Sbjct: 386 YLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASCECPEGYIL--DDGFICTDID 443
Query: 430 ECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPN-GVSCTMGPVSLGPPSGPPDEEDKGE 488
EC G C +C N G+F C C P LA + G C G V G + GE
Sbjct: 444 EC--ENGGFCSGVCHNLPGTFECICGPDSALARHIGTDCDSGKVDGG-------DSGSGE 494
Query: 489 KEGSTVPRAATASPTRG 505
S P + P G
Sbjct: 495 PPPSPTPGSTLTPPAVG 511
>gi|34734064 fibulin 1 isoform B precursor [Homo sapiens]
Length = 601
Score = 151 bits (382), Expect = 2e-36
Identities = 79/200 (39%), Positives = 106/200 (53%), Gaps = 17/200 (8%)
Query: 280 DGSFLC-----GCRPGFRLLDDLVTCASRNPCS--SSPCRGGATCVLGPHGKNYTCRCPQ 332
+GS+ C C G+ L ++ C + C+ + PC G CV P ++ C C
Sbjct: 329 EGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPG--SFRCECKT 386
Query: 333 GYQLDSSQLDCVDVDECQDSP---CAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDEC 389
GY D CVDV+ECQ P C +C NT G + C C VG+ G +C+D++EC
Sbjct: 387 GYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGR-SCEDINEC 445
Query: 390 ALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGP-GGPLCDSLCFNTQG 448
+ SPC+Q C N GS+ C C GY L+ DG C+D+DEC P GG +C C N G
Sbjct: 446 S--SSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPG 503
Query: 449 SFHCGC-LPGWVLAPNGVSC 467
SF C C G+ LAPNG +C
Sbjct: 504 SFQCSCPSSGYRLAPNGRNC 523
Score = 128 bits (322), Expect = 1e-29
Identities = 73/179 (40%), Positives = 90/179 (50%), Gaps = 12/179 (6%)
Query: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSPCR-GGATC--VLGPHGKNYTCRCPQGYQLD 337
GSF C C+ G+ C N C P R G C LG +Y C C G++L
Sbjct: 378 GSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLG----SYLCSCSVGFRLS 433
Query: 338 SSQLDCVDVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECAL--GRSP 395
C D++EC SPC+QEC N G ++C C GY+ C+D+DECAL G
Sbjct: 434 VDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHI 493
Query: 396 CAQGCTNTDGSFHCSC-EEGYVLAGEDGTQCQDVDECV-GPGGPLCDSLCFNTQGSFHC 452
C+ C N GSF CSC GY LA +G CQD+DECV G + CFN QG F C
Sbjct: 494 CSYRCINIPGSFQCSCPSSGYRLA-PNGRNCQDIDECVTGIHNCSINETCFNIQGGFRC 551
Score = 119 bits (297), Expect = 1e-26
Identities = 79/211 (37%), Positives = 103/211 (48%), Gaps = 27/211 (12%)
Query: 269 GGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPC--SSSPCRGGATCV--LGPHGK 324
G C Q C + GD +C C G++LL D V+C N C S CR G +C+ +G
Sbjct: 184 GPCKQQCRDTGD-EVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRC 242
Query: 325 NYTCRCPQGYQLDSSQLDCVDVDECQDS--PCAQE--CVNTPGGFRC----ECWVGYEPG 376
C GY+L C D+DEC+ C + C NT G FRC +C G+
Sbjct: 243 QRDSSCGTGYELTEDN-SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQD 301
Query: 377 GPGEGACQDVDECALGRSPCAQG--CTNTDGSFHC-----SCEEGYVLAGEDGTQCQDVD 429
G C D++EC +PC G C NT+GS+ C +C GY L E+GT+C DVD
Sbjct: 302 ALGN--CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHL-NEEGTRCVDVD 358
Query: 430 ECVGPGGPLCDS--LCFNTQGSFHCGCLPGW 458
EC P P C C N+ GSF C C G+
Sbjct: 359 ECAPPAEP-CGKGHRCVNSPGSFRCECKTGY 388
Score = 95.5 bits (236), Expect = 1e-19
Identities = 66/200 (33%), Positives = 89/200 (44%), Gaps = 29/200 (14%)
Query: 304 NPCSSSPCRGGATCV--LGPHGKNYTCRCPQGYQLDSSQLDCVDVDEC----QDSPCAQE 357
+P + CRGG C G C C GYQL S + C DV+EC +
Sbjct: 173 DPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGES 232
Query: 358 CVNTPGGFRCE----CWVGYEPGGPGEGACQDVDECALGRSPCAQG--CTNTDGSFHC-- 409
C+NT G FRC+ C GYE + +C+D+DEC G C C NT GSF C
Sbjct: 233 CINTVGSFRCQRDSSCGTGYEL--TEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRP 290
Query: 410 --SCEEGYVLAGEDGT-QCQDVDECVGPGGPL-CDSLCFNTQGSFHC-----GCLPGWVL 460
C+ G++ +D C D++EC+ P C NT+GS+ C C G+ L
Sbjct: 291 KLQCKSGFI---QDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHL 347
Query: 461 APNGVSCTMGPVSLGPPSGP 480
G C + PP+ P
Sbjct: 348 NEEGTRC-VDVDECAPPAEP 366
>gi|34734068 fibulin 1 isoform A precursor [Homo sapiens]
Length = 566
Score = 151 bits (382), Expect = 2e-36
Identities = 79/200 (39%), Positives = 106/200 (53%), Gaps = 17/200 (8%)
Query: 280 DGSFLC-----GCRPGFRLLDDLVTCASRNPCS--SSPCRGGATCVLGPHGKNYTCRCPQ 332
+GS+ C C G+ L ++ C + C+ + PC G CV P ++ C C
Sbjct: 329 EGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPG--SFRCECKT 386
Query: 333 GYQLDSSQLDCVDVDECQDSP---CAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDEC 389
GY D CVDV+ECQ P C +C NT G + C C VG+ G +C+D++EC
Sbjct: 387 GYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGR-SCEDINEC 445
Query: 390 ALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGP-GGPLCDSLCFNTQG 448
+ SPC+Q C N GS+ C C GY L+ DG C+D+DEC P GG +C C N G
Sbjct: 446 S--SSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPG 503
Query: 449 SFHCGC-LPGWVLAPNGVSC 467
SF C C G+ LAPNG +C
Sbjct: 504 SFQCSCPSSGYRLAPNGRNC 523
Score = 128 bits (322), Expect = 1e-29
Identities = 73/179 (40%), Positives = 90/179 (50%), Gaps = 12/179 (6%)
Query: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSPCR-GGATC--VLGPHGKNYTCRCPQGYQLD 337
GSF C C+ G+ C N C P R G C LG +Y C C G++L
Sbjct: 378 GSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLG----SYLCSCSVGFRLS 433
Query: 338 SSQLDCVDVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECAL--GRSP 395
C D++EC SPC+QEC N G ++C C GY+ C+D+DECAL G
Sbjct: 434 VDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHI 493
Query: 396 CAQGCTNTDGSFHCSC-EEGYVLAGEDGTQCQDVDECV-GPGGPLCDSLCFNTQGSFHC 452
C+ C N GSF CSC GY LA +G CQD+DECV G + CFN QG F C
Sbjct: 494 CSYRCINIPGSFQCSCPSSGYRLA-PNGRNCQDIDECVTGIHNCSINETCFNIQGGFRC 551
Score = 119 bits (297), Expect = 1e-26
Identities = 79/211 (37%), Positives = 103/211 (48%), Gaps = 27/211 (12%)
Query: 269 GGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPC--SSSPCRGGATCV--LGPHGK 324
G C Q C + GD +C C G++LL D V+C N C S CR G +C+ +G
Sbjct: 184 GPCKQQCRDTGD-EVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRC 242
Query: 325 NYTCRCPQGYQLDSSQLDCVDVDECQDS--PCAQE--CVNTPGGFRC----ECWVGYEPG 376
C GY+L C D+DEC+ C + C NT G FRC +C G+
Sbjct: 243 QRDSSCGTGYELTEDN-SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQD 301
Query: 377 GPGEGACQDVDECALGRSPCAQG--CTNTDGSFHC-----SCEEGYVLAGEDGTQCQDVD 429
G C D++EC +PC G C NT+GS+ C +C GY L E+GT+C DVD
Sbjct: 302 ALGN--CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHL-NEEGTRCVDVD 358
Query: 430 ECVGPGGPLCDS--LCFNTQGSFHCGCLPGW 458
EC P P C C N+ GSF C C G+
Sbjct: 359 ECAPPAEP-CGKGHRCVNSPGSFRCECKTGY 388
Score = 95.5 bits (236), Expect = 1e-19
Identities = 66/200 (33%), Positives = 89/200 (44%), Gaps = 29/200 (14%)
Query: 304 NPCSSSPCRGGATCV--LGPHGKNYTCRCPQGYQLDSSQLDCVDVDEC----QDSPCAQE 357
+P + CRGG C G C C GYQL S + C DV+EC +
Sbjct: 173 DPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGES 232
Query: 358 CVNTPGGFRCE----CWVGYEPGGPGEGACQDVDECALGRSPCAQG--CTNTDGSFHC-- 409
C+NT G FRC+ C GYE + +C+D+DEC G C C NT GSF C
Sbjct: 233 CINTVGSFRCQRDSSCGTGYEL--TEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRP 290
Query: 410 --SCEEGYVLAGEDGT-QCQDVDECVGPGGPL-CDSLCFNTQGSFHC-----GCLPGWVL 460
C+ G++ +D C D++EC+ P C NT+GS+ C C G+ L
Sbjct: 291 KLQCKSGFI---QDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHL 347
Query: 461 APNGVSCTMGPVSLGPPSGP 480
G C + PP+ P
Sbjct: 348 NEEGTRC-VDVDECAPPAEP 366
>gi|34734066 fibulin 1 isoform D [Homo sapiens]
Length = 703
Score = 151 bits (382), Expect = 2e-36
Identities = 79/200 (39%), Positives = 106/200 (53%), Gaps = 17/200 (8%)
Query: 280 DGSFLC-----GCRPGFRLLDDLVTCASRNPCS--SSPCRGGATCVLGPHGKNYTCRCPQ 332
+GS+ C C G+ L ++ C + C+ + PC G CV P ++ C C
Sbjct: 329 EGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPG--SFRCECKT 386
Query: 333 GYQLDSSQLDCVDVDECQDSP---CAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDEC 389
GY D CVDV+ECQ P C +C NT G + C C VG+ G +C+D++EC
Sbjct: 387 GYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGR-SCEDINEC 445
Query: 390 ALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGP-GGPLCDSLCFNTQG 448
+ SPC+Q C N GS+ C C GY L+ DG C+D+DEC P GG +C C N G
Sbjct: 446 S--SSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPG 503
Query: 449 SFHCGC-LPGWVLAPNGVSC 467
SF C C G+ LAPNG +C
Sbjct: 504 SFQCSCPSSGYRLAPNGRNC 523
Score = 128 bits (322), Expect = 1e-29
Identities = 73/179 (40%), Positives = 90/179 (50%), Gaps = 12/179 (6%)
Query: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSPCR-GGATC--VLGPHGKNYTCRCPQGYQLD 337
GSF C C+ G+ C N C P R G C LG +Y C C G++L
Sbjct: 378 GSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLG----SYLCSCSVGFRLS 433
Query: 338 SSQLDCVDVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECAL--GRSP 395
C D++EC SPC+QEC N G ++C C GY+ C+D+DECAL G
Sbjct: 434 VDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHI 493
Query: 396 CAQGCTNTDGSFHCSC-EEGYVLAGEDGTQCQDVDECV-GPGGPLCDSLCFNTQGSFHC 452
C+ C N GSF CSC GY LA +G CQD+DECV G + CFN QG F C
Sbjct: 494 CSYRCINIPGSFQCSCPSSGYRLA-PNGRNCQDIDECVTGIHNCSINETCFNIQGGFRC 551
Score = 119 bits (297), Expect = 1e-26
Identities = 79/211 (37%), Positives = 103/211 (48%), Gaps = 27/211 (12%)
Query: 269 GGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPC--SSSPCRGGATCV--LGPHGK 324
G C Q C + GD +C C G++LL D V+C N C S CR G +C+ +G
Sbjct: 184 GPCKQQCRDTGD-EVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRC 242
Query: 325 NYTCRCPQGYQLDSSQLDCVDVDECQDS--PCAQE--CVNTPGGFRC----ECWVGYEPG 376
C GY+L C D+DEC+ C + C NT G FRC +C G+
Sbjct: 243 QRDSSCGTGYELTEDN-SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQD 301
Query: 377 GPGEGACQDVDECALGRSPCAQG--CTNTDGSFHC-----SCEEGYVLAGEDGTQCQDVD 429
G C D++EC +PC G C NT+GS+ C +C GY L E+GT+C DVD
Sbjct: 302 ALGN--CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHL-NEEGTRCVDVD 358
Query: 430 ECVGPGGPLCDS--LCFNTQGSFHCGCLPGW 458
EC P P C C N+ GSF C C G+
Sbjct: 359 ECAPPAEP-CGKGHRCVNSPGSFRCECKTGY 388
Score = 95.5 bits (236), Expect = 1e-19
Identities = 66/200 (33%), Positives = 89/200 (44%), Gaps = 29/200 (14%)
Query: 304 NPCSSSPCRGGATCV--LGPHGKNYTCRCPQGYQLDSSQLDCVDVDEC----QDSPCAQE 357
+P + CRGG C G C C GYQL S + C DV+EC +
Sbjct: 173 DPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGES 232
Query: 358 CVNTPGGFRCE----CWVGYEPGGPGEGACQDVDECALGRSPCAQG--CTNTDGSFHC-- 409
C+NT G FRC+ C GYE + +C+D+DEC G C C NT GSF C
Sbjct: 233 CINTVGSFRCQRDSSCGTGYEL--TEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRP 290
Query: 410 --SCEEGYVLAGEDGT-QCQDVDECVGPGGPL-CDSLCFNTQGSFHC-----GCLPGWVL 460
C+ G++ +D C D++EC+ P C NT+GS+ C C G+ L
Sbjct: 291 KLQCKSGFI---QDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHL 347
Query: 461 APNGVSCTMGPVSLGPPSGP 480
G C + PP+ P
Sbjct: 348 NEEGTRC-VDVDECAPPAEP 366
>gi|34734062 fibulin 1 isoform C precursor [Homo sapiens]
Length = 683
Score = 151 bits (382), Expect = 2e-36
Identities = 79/200 (39%), Positives = 106/200 (53%), Gaps = 17/200 (8%)
Query: 280 DGSFLC-----GCRPGFRLLDDLVTCASRNPCS--SSPCRGGATCVLGPHGKNYTCRCPQ 332
+GS+ C C G+ L ++ C + C+ + PC G CV P ++ C C
Sbjct: 329 EGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPG--SFRCECKT 386
Query: 333 GYQLDSSQLDCVDVDECQDSP---CAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDEC 389
GY D CVDV+ECQ P C +C NT G + C C VG+ G +C+D++EC
Sbjct: 387 GYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGR-SCEDINEC 445
Query: 390 ALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGP-GGPLCDSLCFNTQG 448
+ SPC+Q C N GS+ C C GY L+ DG C+D+DEC P GG +C C N G
Sbjct: 446 S--SSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPG 503
Query: 449 SFHCGC-LPGWVLAPNGVSC 467
SF C C G+ LAPNG +C
Sbjct: 504 SFQCSCPSSGYRLAPNGRNC 523
Score = 128 bits (322), Expect = 1e-29
Identities = 73/179 (40%), Positives = 90/179 (50%), Gaps = 12/179 (6%)
Query: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSPCR-GGATC--VLGPHGKNYTCRCPQGYQLD 337
GSF C C+ G+ C N C P R G C LG +Y C C G++L
Sbjct: 378 GSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLG----SYLCSCSVGFRLS 433
Query: 338 SSQLDCVDVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECAL--GRSP 395
C D++EC SPC+QEC N G ++C C GY+ C+D+DECAL G
Sbjct: 434 VDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHI 493
Query: 396 CAQGCTNTDGSFHCSC-EEGYVLAGEDGTQCQDVDECV-GPGGPLCDSLCFNTQGSFHC 452
C+ C N GSF CSC GY LA +G CQD+DECV G + CFN QG F C
Sbjct: 494 CSYRCINIPGSFQCSCPSSGYRLA-PNGRNCQDIDECVTGIHNCSINETCFNIQGGFRC 551
Score = 119 bits (297), Expect = 1e-26
Identities = 79/211 (37%), Positives = 103/211 (48%), Gaps = 27/211 (12%)
Query: 269 GGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPC--SSSPCRGGATCV--LGPHGK 324
G C Q C + GD +C C G++LL D V+C N C S CR G +C+ +G
Sbjct: 184 GPCKQQCRDTGD-EVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRC 242
Query: 325 NYTCRCPQGYQLDSSQLDCVDVDECQDS--PCAQE--CVNTPGGFRC----ECWVGYEPG 376
C GY+L C D+DEC+ C + C NT G FRC +C G+
Sbjct: 243 QRDSSCGTGYELTEDN-SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQD 301
Query: 377 GPGEGACQDVDECALGRSPCAQG--CTNTDGSFHC-----SCEEGYVLAGEDGTQCQDVD 429
G C D++EC +PC G C NT+GS+ C +C GY L E+GT+C DVD
Sbjct: 302 ALGN--CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHL-NEEGTRCVDVD 358
Query: 430 ECVGPGGPLCDS--LCFNTQGSFHCGCLPGW 458
EC P P C C N+ GSF C C G+
Sbjct: 359 ECAPPAEP-CGKGHRCVNSPGSFRCECKTGY 388
Score = 95.5 bits (236), Expect = 1e-19
Identities = 66/200 (33%), Positives = 89/200 (44%), Gaps = 29/200 (14%)
Query: 304 NPCSSSPCRGGATCV--LGPHGKNYTCRCPQGYQLDSSQLDCVDVDEC----QDSPCAQE 357
+P + CRGG C G C C GYQL S + C DV+EC +
Sbjct: 173 DPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGES 232
Query: 358 CVNTPGGFRCE----CWVGYEPGGPGEGACQDVDECALGRSPCAQG--CTNTDGSFHC-- 409
C+NT G FRC+ C GYE + +C+D+DEC G C C NT GSF C
Sbjct: 233 CINTVGSFRCQRDSSCGTGYEL--TEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRP 290
Query: 410 --SCEEGYVLAGEDGT-QCQDVDECVGPGGPL-CDSLCFNTQGSFHC-----GCLPGWVL 460
C+ G++ +D C D++EC+ P C NT+GS+ C C G+ L
Sbjct: 291 KLQCKSGFI---QDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHL 347
Query: 461 APNGVSCTMGPVSLGPPSGP 480
G C + PP+ P
Sbjct: 348 NEEGTRC-VDVDECAPPAEP 366
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 146 bits (369), Expect = 5e-35
Identities = 92/267 (34%), Positives = 113/267 (42%), Gaps = 58/267 (21%)
Query: 251 GSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSP 310
G GP C C +NGGC C GS+LC C+PGFRL D TC + N C+
Sbjct: 152 GFQGPRCQYDVDECRTHNGGCQHRCVNT-PGSYLCECKPGFRLHTDSRTCLAINSCALG- 209
Query: 311 CRGGAT--CVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDEC--QDSPCAQECVNTPGGFR 366
GG CV + + C+C G+QL CV C ++ C C G R
Sbjct: 210 -NGGCQHHCVQLTITR-HRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLAR 267
Query: 367 CECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQ 426
CEC VGY+ G+ AC+DVDECA G + CA GC NT GSF C C GY L G DG QC
Sbjct: 268 CECHVGYQLAADGK-ACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYEL-GADGRQCY 325
Query: 427 ----------------------------------------------DVDECVGPGGPLCD 440
DVD+C P C
Sbjct: 326 RIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCAD--SPCCQ 383
Query: 441 SLCFNTQGSFHCGCLPGWVLAPNGVSC 467
+C N G + CGC G+ L+ +G C
Sbjct: 384 QVCTNNPGGYECGCYAGYRLSADGCGC 410
Score = 133 bits (334), Expect = 6e-31
Identities = 86/255 (33%), Positives = 105/255 (41%), Gaps = 58/255 (22%)
Query: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSS--SPCRGGATCVLGP 321
C NGGC C + C CRPGF+L +D C R+PC++ C V G
Sbjct: 206 CALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGL 265
Query: 322 HGKNYTCRCPQGYQLDSSQLDCVDVDECQD--SPCAQECVNTPGGFRCECWVGYEPGGPG 379
C C GYQL + C DVDEC + CA C+NT G F+C C GYE G G
Sbjct: 266 A----RCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADG 321
Query: 380 ---------------------------------------------EGACQDVDECALGRS 394
+ C DVD+CA S
Sbjct: 322 RQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCA--DS 379
Query: 395 PCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCG 453
PC Q CTN G + C C GY L+ DG C+DVDEC G C+ C N GSF C
Sbjct: 380 PCCQQVCTNNPGGYECGCYAGYRLSA-DGCGCEDVDECASSRGG-CEHHCTNLAGSFQCS 437
Query: 454 CLPGWVLAPNGVSCT 468
C G+ L + C+
Sbjct: 438 CEAGYRLHEDRRGCS 452
Score = 131 bits (329), Expect = 2e-30
Identities = 73/171 (42%), Positives = 90/171 (52%), Gaps = 21/171 (12%)
Query: 271 CHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASR-----NPCSSSPCRGGATCVLGPHGKN 325
C C GSF C C G+ L D C N C ++ GG + HG +
Sbjct: 296 CAHGCLNT-QGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEAN--NGGCS-----HGCS 347
Query: 326 YT-----CRCPQGYQLDSSQLDCVDVDECQDSPCAQE-CVNTPGGFRCECWVGYEPGGPG 379
+T C CP+GY+LD+ Q C+DVD+C DSPC Q+ C N PGG+ C C+ GY G
Sbjct: 348 HTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADG 407
Query: 380 EGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDE 430
G C+DVDECA R C CTN GSF CSCE GY L ED C ++E
Sbjct: 408 CG-CEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRL-HEDRRGCSPLEE 456
Score = 65.9 bits (159), Expect = 1e-10
Identities = 48/143 (33%), Positives = 64/143 (44%), Gaps = 13/143 (9%)
Query: 329 RCPQGYQLDSSQLDCVDVDECQDSPCAQECVNTPGGFR-CECWVGYEPGGPGEGACQ-DV 386
RC +G+ + C+ EC S C PG + C C G++ GP CQ DV
Sbjct: 109 RCCRGWMQQPDEEGCLSA-ECSASLCFHGGRCVPGSAQPCHCPPGFQ--GP---RCQYDV 162
Query: 387 DECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDEC-VGPGGPLCDSLCFN 445
DEC C C NT GS+ C C+ G+ L D C ++ C +G GG C C
Sbjct: 163 DECRTHNGGCQHRCVNTPGSYLCECKPGFRL-HTDSRTCLAINSCALGNGG--CQHHCVQ 219
Query: 446 TQGSFH-CGCLPGWVLAPNGVSC 467
+ H C C PG+ L +G C
Sbjct: 220 LTITRHRCQCRPGFQLQEDGRHC 242
Score = 56.2 bits (134), Expect = 9e-08
Identities = 67/244 (27%), Positives = 82/244 (33%), Gaps = 25/244 (10%)
Query: 299 TCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQEC 358
TC+ RN G +C LG G++ CP G + L+C + P C
Sbjct: 1304 TCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTC 1363
Query: 359 VNTPGGFRCECWVGYEPGGPGEGACQDVDECALGR--SPCAQGCTNTDGSFHCSCEEGYV 416
PG + C PG G G CQ + C G P + C G CE G
Sbjct: 1364 RCGPGFYGQACEHPCPPGFHGAG-CQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERG-C 1421
Query: 417 LAGEDGTQCQDVDECVGPGGPLCD---SLCFNTQGSFHCGCLPGWVLAPNGVSCTM---- 469
G G C +C GG CD LC G C G SCT+
Sbjct: 1422 EPGSFGEGCHQRCDC--DGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDC 1479
Query: 470 -GPVSLGPPSGPPDEEDKGEKEGSTVPRAATASPTRGPE------GTPKATPTTSRPSLS 522
G P SG D G P P R PE G+ P +SRP+
Sbjct: 1480 GGGADCDPVSGQCHCVD-----GYMGPTCREGGPLRLPENPSLAQGSAGTLPASSRPTSR 1534
Query: 523 SDAP 526
S P
Sbjct: 1535 SGGP 1538
Score = 54.3 bits (129), Expect = 3e-07
Identities = 60/222 (27%), Positives = 81/222 (36%), Gaps = 35/222 (15%)
Query: 264 CNFNNGGCHQDCFEGGDGSFLCG--CRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGP 321
C GC DC EG G +C C P + +C+ +N + G C G
Sbjct: 533 CLLGLDGC--DCPEGWTG-LICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGV 589
Query: 322 HGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEG 381
G N CP+GY + C + + C+ PG + C + P G G
Sbjct: 590 SGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPG 649
Query: 382 ACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDE----------- 430
C + +C P Q C DGS CSC+ G+ G +CQ E
Sbjct: 650 -CSEECQCV---QPHTQSCDKRDGS--CSCKAGF-----RGERCQAECELGYFGPGCWQA 698
Query: 431 CVGPGGPLCDSLCFNTQGSFHCG--CLPGWVLAPNGVSCTMG 470
C P G CDS+ S CG C G+ G C +G
Sbjct: 699 CTCPVGVACDSV------SGECGKRCPAGFQGEDCGQECPVG 734
Score = 51.6 bits (122), Expect = 2e-06
Identities = 65/248 (26%), Positives = 81/248 (32%), Gaps = 52/248 (20%)
Query: 240 CKEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSF----LCGCRPGFRLLD 295
C ++ P F G C +G N C C GG C C PG D
Sbjct: 714 CGKRCPAGFQGEDCGQECPVGTFGVN-----CSSSCSCGGAPCHGVTGQCRCPPGRTGED 768
Query: 296 DLVTC--------------ASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQL 341
C A ++ P G C+ G G CP G+ S Q
Sbjct: 769 CEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQT 828
Query: 342 DCVDVDECQDSPCAQECVNTPG--GFRCE--CWVGYEPGGPGEGACQDVDECALGRSPCA 397
C ++ P C PG GF C+ C G+ GP C C+ G C
Sbjct: 829 RCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGH--WGPD---CSHPCNCSAGHGSC- 882
Query: 398 QGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDEC-VGPGGPLCDSLCFNTQG------SF 450
S C CE GYV G +C+ +C G GP C+ C G S
Sbjct: 883 -----DAISGLCLCEAGYV-----GPRCE--QQCPQGHFGPGCEQRCQCQHGAACDHVSG 930
Query: 451 HCGCLPGW 458
C C GW
Sbjct: 931 ACTCPAGW 938
Score = 50.1 bits (118), Expect = 7e-06
Identities = 57/209 (27%), Positives = 69/209 (33%), Gaps = 27/209 (12%)
Query: 266 FNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKN 325
F GC Q C GSF C + C NP + P G +C G HG +
Sbjct: 1153 FTGSGCEQAC---PPGSFGEDCA-------QMCQCPGENP-ACHPATGTCSCAAGYHGPS 1201
Query: 326 YTCRCPQG-YQLDSSQL-DCVDVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEGAC 383
RCP G Y QL C++ C + A C G C GP C
Sbjct: 1202 CQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPN---C 1258
Query: 384 QDVDECALGRS--PCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDS 441
V C G + P C G CE G G C+ C G
Sbjct: 1259 THVCGCGQGAACDPVTGTCLCPPGRAGVRCERG-CPQNRFGVGCEHTCSCRNGG------ 1311
Query: 442 LCFNTQGSFHCGCLPGWVLAPNGVSCTMG 470
LC + GS C C GW ++C G
Sbjct: 1312 LCHASNGS--CSCGLGWTGRHCELACPPG 1338
Score = 47.0 bits (110), Expect = 6e-05
Identities = 61/227 (26%), Positives = 78/227 (34%), Gaps = 24/227 (10%)
Query: 240 CKEKAPDVFDWGSSGPLCVSP---KYG--CNFNNGGCHQDCFEGGDGSFL-CGCRPGFRL 293
C+++ P G GP C ++G C+ +G C C G G+F C GF
Sbjct: 900 CEQQCPQ----GHFGPGCEQRCQCQHGAACDHVSGAC--TCPAGWRGTFCEHACPAGFFG 953
Query: 294 LDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSP 353
LD C + G C G G CP + C + P
Sbjct: 954 LDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDP 1013
Query: 354 CAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEE 413
+C PG C G G+ C+ C C G T S HC+C E
Sbjct: 1014 VHGQCHCAPGWMGPSCLQACPAGLYGDN-CR--HSCL-----CQNGGTCDPVSGHCACPE 1065
Query: 414 GYV-LAGEDGTQCQDVDE-CVGPGGPLCDSLCFNTQGSFHCGCLPGW 458
G+ LA E +DV C GG L LC G C C GW
Sbjct: 1066 GWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTG--RCLCPAGW 1110
Score = 39.7 bits (91), Expect = 0.009
Identities = 54/210 (25%), Positives = 66/210 (31%), Gaps = 63/210 (30%)
Query: 257 CVSPKYGCNFNNGGCHQDCF-------EGGDGSFLCG-----------CRPGFRLLDDLV 298
C +YG CH +C E G+ CG C PGF
Sbjct: 1335 CPPGRYGA-----ACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQG 1389
Query: 299 TCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQEC 358
C ++ P G C G HG C +G C+ + C
Sbjct: 1390 LCWCQHGAPCDPISGRCLCPAGFHGH----FCERG---------------CEPGSFGEGC 1430
Query: 359 VNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRS------PCAQGCTNTDGSFHCSCE 412
RC+C G P P G C C GRS C +G + HC C
Sbjct: 1431 HQ-----RCDC-DGGAPCDPVTGLCL----CPPGRSGATCNLDCRRGQFGPSCTLHCDCG 1480
Query: 413 EGYVLAGEDGTQCQDVDECVGP----GGPL 438
G G QC VD +GP GGPL
Sbjct: 1481 GGADCDPVSG-QCHCVDGYMGPTCREGGPL 1509
Score = 35.4 bits (80), Expect = 0.17
Identities = 46/178 (25%), Positives = 59/178 (33%), Gaps = 22/178 (12%)
Query: 300 CASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQECV 359
CA N S P G C G G + CP G D+ + C+ + P + C
Sbjct: 1003 CACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCA 1062
Query: 360 NTPG--GFRC--ECWV-GYEPGGPGEGACQDVDEC--ALGRSPCAQGCTNTDGSFHCSCE 412
G G C EC G G C + C GR C G T C
Sbjct: 1063 CPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPC--- 1119
Query: 413 EGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSCTMG 470
L G G C C P G + C + G+ C C PG+ + +C G
Sbjct: 1120 ----LRGWFGEAC--AQRCSCPPG----AACHHVTGA--CRCPPGFTGSGCEQACPPG 1165
>gi|24430141 fibrillin 1 precursor [Homo sapiens]
Length = 2871
Score = 143 bits (361), Expect = 4e-34
Identities = 82/214 (38%), Positives = 110/214 (51%), Gaps = 20/214 (9%)
Query: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGP 321
C+ NGGC C +GS+ C C+PGF L+ D +C + C +P C GG C P
Sbjct: 1201 CSIMNGGCETFC-TNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGG-QCTNIP 1258
Query: 322 HGKNYTCRCPQGYQLDSSQLDCVDVDECQDSP---CAQECVNTPGGFRCECWVGYEPGGP 378
Y C C G+ CVDV+EC +P + C NT G F C C +GY G
Sbjct: 1259 --GEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYS-GKK 1315
Query: 379 GEGACQDVDECALGRSPCAQG--CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGG 436
G+ C D++EC +G C + CTNT GSF CSC G++ DG +C D+DEC G
Sbjct: 1316 GKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWI---GDGIKCTDLDEC-SNGT 1371
Query: 437 PLCD--SLCFNTQGSFHCGCLPGWVLAPNGVSCT 468
+C + C NT GS+ C C G+ +G +CT
Sbjct: 1372 HMCSQHADCKNTMGSYRCLCKEGY--TGDGFTCT 1403
Score = 138 bits (348), Expect = 1e-32
Identities = 78/194 (40%), Positives = 99/194 (51%), Gaps = 17/194 (8%)
Query: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATC--VLGPHGKNYTCRCPQGYQLDS 338
GSF C C GF+ DD C N C C G TC +G ++ CRC G+ L
Sbjct: 1870 GSFYCLCHTGFKTNDDQTMCLDINECERDAC-GNGTCRNTIG----SFNCRCNHGFILSH 1924
Query: 339 SQLDCVDVDECQDSP---CAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRS 394
+ DC+DVDEC C +C+NT G F+C+C GYE G C D++EC L
Sbjct: 1925 NN-DCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGR-TCVDINECLLEPR 1982
Query: 395 PCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCG 453
CA G C N DGS+ C C GY L E +C+D+DECV C NT+GSF C
Sbjct: 1983 KCAPGTCQNLDGSYRCICPPGYSLQNE---KCEDIDECVEEPEICALGTCSNTEGSFKCL 2039
Query: 454 CLPGWVLAPNGVSC 467
C G+ L+ +G C
Sbjct: 2040 CPEGFSLSSSGRRC 2053
Score = 136 bits (342), Expect = 7e-32
Identities = 82/216 (37%), Positives = 113/216 (52%), Gaps = 21/216 (9%)
Query: 257 CVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGAT 316
C +Y C NG C GS C C GF+L D C + C +PC GG
Sbjct: 453 CQLVRYLCQ--NGRCIPT-----PGSCRCECNKGFQL-DLRGECIDVDECEKNPCAGGE- 503
Query: 317 CVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSP--CAQ-ECVNTPGGFRCECWVGY 373
C+ + +YTC+C GYQ ++ +C D+DEC + C C+NT G F C C G+
Sbjct: 504 CI--NNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGF 561
Query: 374 EPGGPGEGACQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECV 432
G+ C+D+DEC++ R+ C G C N DGSF C C+ G+ LA DG C+D++EC
Sbjct: 562 HVTRDGKN-CEDMDECSI-RNMCLNGMCINEDGSFKCICKPGFQLA-SDGRYCKDINECE 618
Query: 433 GPGGPLC-DSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
PG +C + C NT GS+ C C PG + +G C
Sbjct: 619 TPG--ICMNGRCVNTDGSYRCECFPGLAVGLDGRVC 652
Score = 132 bits (333), Expect = 8e-31
Identities = 87/255 (34%), Positives = 121/255 (47%), Gaps = 18/255 (7%)
Query: 220 AANVACGEGDKDETQSHYFLCKEKAPD-VFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEG 278
A N C + T LC + P V D + P+ + C G C
Sbjct: 1728 AWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDE---CREIPGVCENGVCIN 1784
Query: 279 GDGSFLCGCRPGFRLLDDLVTCASRNPCSSSP-CRGGATCVLGPHGKNYTCRCPQGYQLD 337
GSF C C GF D L+ C + C + P C+ A C+ +Y C C GY+
Sbjct: 1785 MVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECI--NTAGSYRCDCKPGYRFT 1842
Query: 338 SSQLDCVDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRS 394
S+ C D +ECQ+ P C+ +C++T G F C C G++ + C D++EC R
Sbjct: 1843 STG-QCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDD-QTMCLDINECE--RD 1898
Query: 395 PCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLC-DSLCFNTQGSFHC 452
C G C NT GSF+C C G++L+ + C DVDEC G LC + C NT GSF C
Sbjct: 1899 ACGNGTCRNTIGSFNCRCNHGFILSHNN--DCIDVDECASGNGNLCRNGQCINTVGSFQC 1956
Query: 453 GCLPGWVLAPNGVSC 467
C G+ +AP+G +C
Sbjct: 1957 QCNEGYEVAPDGRTC 1971
Score = 132 bits (332), Expect = 1e-30
Identities = 79/208 (37%), Positives = 106/208 (50%), Gaps = 19/208 (9%)
Query: 267 NNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATC--VLGPH 322
+N G H C GSF C C PG+ + D + C + CS+ C A C +G
Sbjct: 1331 HNCGKHAVCTNTA-GSFKCSCSPGW--IGDGIKCTDLDECSNGTHMCSQHADCKNTMG-- 1385
Query: 323 GKNYTCRCPQGYQLDSSQLDCVDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPG 379
+Y C C +GY D C D+DEC ++ C +C+N PGG+RCEC +G+ P G
Sbjct: 1386 --SYRCLCKEGYTGDG--FTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADG 1441
Query: 380 EGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLC 439
+ AC+D+DEC+L C N G F C CE GY L G C DV+EC+ P +
Sbjct: 1442 K-ACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYEL-DRSGGNCTDVNECLDPTTCIS 1499
Query: 440 DSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
+ C NT GS+ C C P + L P V C
Sbjct: 1500 GN-CVNTPGSYICDCPPDFELNPTRVGC 1526
Score = 130 bits (328), Expect = 3e-30
Identities = 75/196 (38%), Positives = 103/196 (52%), Gaps = 15/196 (7%)
Query: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGKNYTCRCPQGYQLDS 338
GSF C C GF L + C + C SP C G CV P ++ C+C +GY+
Sbjct: 1049 GSFKCRCDSGFALDSEERNCTDIDECRISPDLC-GRGQCVNTPG--DFECKCDEGYESGF 1105
Query: 339 SQL-DCVDVDECQDSPCAQE---CVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRS 394
+ +C+D+DECQ P C NT G +RCEC G++ P AC D++EC L
Sbjct: 1106 MMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLS-PNISACIDINECELSAH 1164
Query: 395 PCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDEC-VGPGGPLCDSLCFNTQGSFHC 452
C G C N G + C+C GY + D C D+DEC + GG C++ C N++GS+ C
Sbjct: 1165 LCPNGRCVNLIGKYQCACNPGYH-STPDRLFCVDIDECSIMNGG--CETFCTNSEGSYEC 1221
Query: 453 GCLPGWVLAPNGVSCT 468
C PG+ L P+ SCT
Sbjct: 1222 SCQPGFALMPDQRSCT 1237
Score = 124 bits (310), Expect = 4e-28
Identities = 81/246 (32%), Positives = 109/246 (44%), Gaps = 56/246 (22%)
Query: 269 GGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPC--SSSPCRGG----------AT 316
G CH +GS+ C C PG +L ++ C N C S+ C G
Sbjct: 1127 GVCHNT-----EGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCA 1181
Query: 317 CVLGPHGK----------------------------NYTCRCPQGYQLDSSQLDCVDVDE 348
C G H +Y C C G+ L Q C D+DE
Sbjct: 1182 CNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDE 1241
Query: 349 CQDSP--C-AQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQG-CTNTD 404
C+D+P C +C N PG +RC C+ G+ C DV+EC L + C G C NT
Sbjct: 1242 CEDNPNICDGGQCTNIPGEYRCLCYDGF-MASEDMKTCVDVNECDLNPNICLSGTCENTK 1300
Query: 405 GSFHCSCEEGYVLAGEDG-TQCQDVDEC-VGPGGPLCDSLCFNTQGSFHCGCLPGWVLAP 462
GSF C C+ GY +G+ G T C D++EC +G ++C NT GSF C C PGW+
Sbjct: 1301 GSFICHCDMGY--SGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWI--G 1356
Query: 463 NGVSCT 468
+G+ CT
Sbjct: 1357 DGIKCT 1362
Score = 117 bits (292), Expect = 4e-26
Identities = 68/186 (36%), Positives = 89/186 (47%), Gaps = 14/186 (7%)
Query: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSP---CRGGATCVLGPHGKNYTCRCPQGYQLD 337
GS+ C C+PG+R C RN C P G +G ++ C C G++ +
Sbjct: 1829 GSYRCDCKPGYRFTST-GQCNDRNECQEIPNICSHGQCIDTVG----SFYCLCHTGFKTN 1883
Query: 338 SSQLDCVDVDECQDSPCAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSP- 395
Q C+D++EC+ C C NT G F C C G+ + C DVDECA G
Sbjct: 1884 DDQTMCLDINECERDACGNGTCRNTIGSFNCRCNHGFILSHNND--CIDVDECASGNGNL 1941
Query: 396 CAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGC 454
C G C NT GSF C C EGY +A DG C D++EC+ C N GS+ C C
Sbjct: 1942 CRNGQCINTVGSFQCQCNEGYEVA-PDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCIC 2000
Query: 455 LPGWVL 460
PG+ L
Sbjct: 2001 PPGYSL 2006
Score = 117 bits (292), Expect = 4e-26
Identities = 71/215 (33%), Positives = 97/215 (45%), Gaps = 10/215 (4%)
Query: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQ 340
G F C C PGF +C N C+S G+ + ++TC C +G+ LD +
Sbjct: 2505 GGFTCKCPPGFT--QHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTG 2562
Query: 341 LDCVDVDECQDSP-CAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQG 399
C DVDEC+ + C C N GG+RC C GY C D +EC
Sbjct: 2563 SSCEDVDECEGNHRCQHGCQNIIGGYRCSCPQGYLQHYQWN-QCVDENECLSAHICGGAS 2621
Query: 400 CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWV 459
C NT GS+ C C G+ G CQD++EC P C C NT+G + CGC PG+
Sbjct: 2622 CHNTLGSYKCMCPAGFQYEQFSGG-CQDINECGSAQAP-CSYGCSNTEGGYLCGCPPGYF 2679
Query: 460 LAPNGVSCTMGPVSLGPPSGPPDEEDKGEKEGSTV 494
G C G +G G P+ GE + +++
Sbjct: 2680 RIGQG-HCVSG---MGMGRGNPEPPVSGEMDDNSL 2710
Score = 116 bits (290), Expect = 7e-26
Identities = 90/318 (28%), Positives = 129/318 (40%), Gaps = 59/318 (18%)
Query: 159 KWSEGPCGSPGSPGSNIEGFVCKFSFKGMCRPLALGGPGQVTYTTPFQTTSSSLEAVPFA 218
K+ G C SP S + + C +G P L P + + + P+
Sbjct: 2064 KFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCEL---------CPTEPDEAFRQICPYG 2114
Query: 219 SAANVACGEGDKDETQSHYFLCKEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEG 278
S V + D + CKE PDV G C++
Sbjct: 2115 SGIIVGPDDSAVDMDE-----CKE--PDVCKHGQ----CINT------------------ 2145
Query: 279 GDGSFLCGCRPGFRLLD----DLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGY 334
DGS+ C C G+ L D C+ NPC + C+ V+G + C C +G+
Sbjct: 2146 -DGSYRCECPFGYILAGNECVDTDECSVGNPCGNGTCKN----VIG----GFECTCEEGF 2196
Query: 335 QLDSSQLDCVDVDECQDSP--CAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALG 392
+ + C D++EC +P CA CVNT G + C+C VGY C+D DEC G
Sbjct: 2197 E-PGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLR-EDRRMCKDEDECEEG 2254
Query: 393 RSPCAQG---CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGS 449
+ C + C N G++ C C GY DG C D +EC G + C NT+GS
Sbjct: 2255 KHDCTEKQMECKNLIGTYMCICGPGYQRR-PDGEGCVDENECQTKPGICENGRCLNTRGS 2313
Query: 450 FHCGCLPGWVLAPNGVSC 467
+ C C G+ +PN C
Sbjct: 2314 YTCECNDGFTASPNQDEC 2331
Score = 113 bits (282), Expect = 6e-25
Identities = 66/194 (34%), Positives = 94/194 (48%), Gaps = 13/194 (6%)
Query: 281 GSFLCGCRPGFRL-LDDLVTCASRNPCSSSP--CRGGATCVLGPHGKNYTCRCPQGYQLD 337
G F C C G+ + C + C P CRGG V +Y C CP G+QL
Sbjct: 1091 GDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGG---VCHNTEGSYRCECPPGHQLS 1147
Query: 338 SSQLDCVDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRS 394
+ C+D++EC+ S C CVN G ++C C GY P C D+DEC++
Sbjct: 1148 PNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYH-STPDRLFCVDIDECSIMNG 1206
Query: 395 PCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCD-SLCFNTQGSFHCG 453
C CTN++GS+ CSC+ G+ L D C D+DEC +CD C N G + C
Sbjct: 1207 GCETFCTNSEGSYECSCQPGFALM-PDQRSCTDIDEC-EDNPNICDGGQCTNIPGEYRCL 1264
Query: 454 CLPGWVLAPNGVSC 467
C G++ + + +C
Sbjct: 1265 CYDGFMASEDMKTC 1278
Score = 112 bits (279), Expect = 1e-24
Identities = 91/278 (32%), Positives = 116/278 (41%), Gaps = 47/278 (16%)
Query: 225 CGEGDKDETQSHYFLCKEKAPDVFDWGSSGPLCVSPKYG---CNFNNGGCH--------- 272
C G T+ + K P+ F SSG C + F G C
Sbjct: 2024 CALGTCSNTEGSF---KCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSK 2080
Query: 273 QDCF-----EG-GDGSFLCGCRP--GFRLL----DDLVTCASRNPCSSSPCRGGATCVLG 320
Q+C EG GD LC P FR + ++ + C+ C
Sbjct: 2081 QECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVC--- 2137
Query: 321 PHGK------NYTCRCPQGYQLDSSQLDCVDVDECQ-DSPCAQ-ECVNTPGGFRCECWVG 372
HG+ +Y C CP GY L ++ CVD DEC +PC C N GGF C C G
Sbjct: 2138 KHGQCINTDGSYRCECPFGYILAGNE--CVDTDECSVGNPCGNGTCKNVIGGFECTCEEG 2195
Query: 373 YEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECV 432
+EPG C+D++ECA CA C NT GS+ C C GYVL ED C+D DEC
Sbjct: 2196 FEPGPMM--TCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLR-EDRRMCKDEDEC- 2251
Query: 433 GPGGPLCDSL---CFNTQGSFHCGCLPGWVLAPNGVSC 467
G C C N G++ C C PG+ P+G C
Sbjct: 2252 EEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGC 2289
Score = 108 bits (270), Expect = 2e-23
Identities = 75/227 (33%), Positives = 97/227 (42%), Gaps = 38/227 (16%)
Query: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTC---------------------AS 302
C G C GS+ C C GF + C ++
Sbjct: 2295 CQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSN 2354
Query: 303 RNPCSSSPC-----RG-GATCVLGPHGKNYTCR--CPQGYQLDSSQLDCVDVDECQ---D 351
RNP + S C RG G C + P + CP G ++ D+DEC+ D
Sbjct: 2355 RNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNG---ADIDECKVIHD 2411
Query: 352 SPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSC 411
ECVN G + C C GY P G +C D++EC PC C NT+GS+ CSC
Sbjct: 2412 VCRNGECVNDRGSYHCICKTGYTPDITGT-SCVDLNECNQAPKPCNFICKNTEGSYQCSC 2470
Query: 412 EEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGW 458
+GY+L EDG C+D+DEC C LC NT G F C C PG+
Sbjct: 2471 PKGYILQ-EDGRSCKDLDECATKQHN-CQFLCVNTIGGFTCKCPPGF 2515
Score = 98.2 bits (243), Expect = 2e-20
Identities = 72/221 (32%), Positives = 99/221 (44%), Gaps = 41/221 (18%)
Query: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGKNYTCRCPQGYQLDS 338
G+++C C PG++ D C N C + P C G L G +YTC C G+
Sbjct: 2270 GTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRC--LNTRG-SYTCECNDGFTASP 2326
Query: 339 SQLDCVDVDE-----------CQ------DSPCAQECVNTPG---GFRCECW-----VGY 373
+Q +C+D E CQ + EC G G CE V +
Sbjct: 2327 NQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAF 2386
Query: 374 E---PGGPG---EGACQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQ 426
+ P G G GA D+DEC + C G C N GS+HC C+ GY GT C
Sbjct: 2387 KKLCPHGRGFMTNGA--DIDECKVIHDVCRNGECVNDRGSYHCICKTGYT-PDITGTSCV 2443
Query: 427 DVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
D++EC P C+ +C NT+GS+ C C G++L +G SC
Sbjct: 2444 DLNECNQAPKP-CNFICKNTEGSYQCSCPKGYILQEDGRSC 2483
Score = 87.4 bits (215), Expect = 4e-17
Identities = 66/228 (28%), Positives = 94/228 (41%), Gaps = 28/228 (12%)
Query: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPC--SSSPCRGGATCVLGP 321
C + C E G++ C C G+ + C N C +S C G C P
Sbjct: 727 CALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQ-CRNTP 785
Query: 322 HGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQE-CVNTPGGFRCECWVGYEPGGPGE 380
++ C CP+G+ C D+DEC+ SPC C N+PG F CEC P +
Sbjct: 786 G--SFVCTCPKGFIYKPDLKTCEDIDECESSPCINGVCKNSPGSFICEC-SSESTLDPTK 842
Query: 381 GACQDV-----------DECAL---GRSPCAQGCTNTDGSFHCSCEEGYV--LAGED--- 421
C + C + G + +Q C++ ++ C V + G+
Sbjct: 843 TICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSR 902
Query: 422 --GTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
GTQC+D+DEC G + LC NT+GSF C C G L G C
Sbjct: 903 IKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRIC 950
Score = 84.3 bits (207), Expect = 3e-16
Identities = 81/263 (30%), Positives = 101/263 (38%), Gaps = 67/263 (25%)
Query: 242 EKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCA 301
E APD G CV C C + DGS+ C C PG+ L ++ C
Sbjct: 1963 EVAPD-------GRTCVDINE-CLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNE--KCE 2012
Query: 302 SRNPCSSSPCRGGATCVLGPHGK---NYTCRCPQGYQLDSSQLDCVDV------------ 346
+ C P C LG ++ C CP+G+ L SS C D+
Sbjct: 2013 DIDECVEEP----EICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGG 2068
Query: 347 ------------DEC--------QDSPCAQECVNTPG-GFRCECWVGYEPG---GPGEGA 382
EC PC + C P FR C Y G GP + A
Sbjct: 2069 KCSSPKSRNHSKQECCCALKGEGWGDPC-ELCPTEPDEAFRQIC--PYGSGIIVGPDDSA 2125
Query: 383 CQDVDECALGRSP--CAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLC 439
D+DEC + P C G C NTDGS+ C C GY+LA G +C D DEC G P
Sbjct: 2126 V-DMDEC---KEPDVCKHGQCINTDGSYRCECPFGYILA---GNECVDTDEC-SVGNPCG 2177
Query: 440 DSLCFNTQGSFHCGCLPGWVLAP 462
+ C N G F C C G+ P
Sbjct: 2178 NGTCKNVIGGFECTCEEGFEPGP 2200
Score = 82.4 bits (202), Expect = 1e-15
Identities = 70/223 (31%), Positives = 86/223 (38%), Gaps = 39/223 (17%)
Query: 271 CHQDCFEGGDGSF-LCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCR 329
C+ C GG S C C+ G+ + P S C G CV P+ C
Sbjct: 119 CNIRCMNGGSCSDDHCLCQKGY------IGTHCGQPVCESGCLNGGRCV-APN----RCA 167
Query: 330 CPQGYQLDSSQLD-----CVDV---DECQDSPCAQECVNT--------PGGFRCE----- 368
C G+ + D C V CQ C T G CE
Sbjct: 168 CTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQ 227
Query: 369 ---CWVGYEPGGPGEGACQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQ 424
C G+ P GACQDVDEC C G C NT GSF C C G+ L E +
Sbjct: 228 PHPCRRGFIPN-IRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKL-NEVSQK 285
Query: 425 CQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
C+D+DEC G C NT S+ C C PG+ +P+G C
Sbjct: 286 CEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRC 328
Score = 82.4 bits (202), Expect = 1e-15
Identities = 64/227 (28%), Positives = 86/227 (37%), Gaps = 51/227 (22%)
Query: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATC--VLGPHGKNYTCRCPQGYQLDS 338
GSF C C G+ L +D C N C + G TC +G NYTC CP Y +
Sbjct: 1627 GSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVG----NYTCICPPDYMQVN 1682
Query: 339 SQLDCVD-----------------------------------VDECQDSPCAQECVNTPG 363
+C+D + + PC Q + +
Sbjct: 1683 GGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTD 1742
Query: 364 GFRCECWVGYEPGGPGE---GACQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAG 419
F C PG + G D+DEC C G C N GSF C C G+
Sbjct: 1743 EFATLCG-SQRPGFVIDIYTGLPVDIDECREIPGVCENGVCINMVGSFRCECPVGF-FYN 1800
Query: 420 EDGTQCQDVDECVGPGGPLC--DSLCFNTQGSFHCGCLPGWVLAPNG 464
+ C+D+DEC GP+C ++ C NT GS+ C C PG+ G
Sbjct: 1801 DKLLVCEDIDEC--QNGPVCQRNAECINTAGSYRCDCKPGYRFTSTG 1845
Score = 81.6 bits (200), Expect = 2e-15
Identities = 70/266 (26%), Positives = 103/266 (38%), Gaps = 62/266 (23%)
Query: 239 LCKEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLV 298
L + + D+ + +G +C NNG C DGSF C C GF + D
Sbjct: 523 LTRTECRDIDECLQNGRIC---------NNGRCINT-----DGSFHCVCNAGFHVTRDGK 568
Query: 299 TCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQE- 357
C + CS C+ ++ C C G+QL S C D++EC+
Sbjct: 569 NCEDMDECSIRNMCLNGMCI--NEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNG 626
Query: 358 -CVNTPGGFRCECWVGYEPGGPGEGACQDVD------------EC------ALGRSPCAQ 398
CVNT G +RCEC+ G G G C D +C A+ +S C
Sbjct: 627 RCVNTDGSYRCECFPGLAVGLDGR-VCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECC- 684
Query: 399 GCTNTDGSFH-----------------CSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDS 441
C +T+ +F CS G AG D +C +D + P G
Sbjct: 685 -CASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECA-LDPDICPNG----- 737
Query: 442 LCFNTQGSFHCGCLPGWVLAPNGVSC 467
+C N +G++ C C G+ + G +C
Sbjct: 738 ICENLRGTYKCICNSGYEVDSTGKNC 763
Score = 75.9 bits (185), Expect = 1e-13
Identities = 76/279 (27%), Positives = 100/279 (35%), Gaps = 49/279 (17%)
Query: 229 DKDETQSHYFLCKEKAPDVFDWGSSGPLCVSPKYG----------CNFNNGGCHQDCFEG 278
D DE + +C + A GS LC G C+ N C
Sbjct: 1363 DLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLN 1422
Query: 279 GDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDS 338
G + C C GF D C + CS TC P + C C GY+LD
Sbjct: 1423 APGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPG--LFRCECEIGYELDR 1480
Query: 339 SQLDCVDVDECQD-SPCAQ-ECVNTPGGFRCECWVGYE---------------------- 374
S +C DV+EC D + C CVNTPG + C+C +E
Sbjct: 1481 SGGNCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRP 1540
Query: 375 PGGPGEGACQD-----VDE----CALGRS---PCAQGCTNTDGSFHCSCEEGYVLAGEDG 422
G G+ AC + V + C+LG++ PC + C G
Sbjct: 1541 RGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPI 1600
Query: 423 TQC-QDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVL 460
T +D+DEC G C NT GSF C C G+ L
Sbjct: 1601 TVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYL 1639
Score = 70.1 bits (170), Expect = 6e-12
Identities = 40/116 (34%), Positives = 53/116 (45%), Gaps = 9/116 (7%)
Query: 268 NGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATC--VLGPHGKN 325
N C C + G + C C G+ C N C S+ GGA+C LG +
Sbjct: 2574 NHRCQHGC-QNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNTLG----S 2628
Query: 326 YTCRCPQGYQLDSSQLDCVDVDEC--QDSPCAQECVNTPGGFRCECWVGYEPGGPG 379
Y C CP G+Q + C D++EC +PC+ C NT GG+ C C GY G G
Sbjct: 2629 YKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYGCSNTEGGYLCGCPPGYFRIGQG 2684
Score = 55.8 bits (133), Expect = 1e-07
Identities = 62/235 (26%), Positives = 85/235 (36%), Gaps = 51/235 (21%)
Query: 284 LCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGKNYTCRCPQGYQLDSSQL 341
LC GFR V + C P C+GG + G ++ CRCP GY L+
Sbjct: 1588 LCPGGEGFRPNPITVILEDIDECQELPGLCQGGKC--INTFG-SFQCRCPTGYYLNEDTR 1644
Query: 342 DCVDVDECQDSPCA--QECVNTPGGFRCECWVGYEPGGPGEGACQDVDE----------- 388
C DV+EC+ C NT G + C C Y G C D+
Sbjct: 1645 VCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNN-CMDMRRSLCYRNYYADN 1703
Query: 389 -----------------CA--LGRS---PCAQGCTNTDGSFHCSC---EEGYVLAGEDGT 423
C+ +GR+ PC Q + F C G+V+ G
Sbjct: 1704 QTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGL 1763
Query: 424 QCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGW------VLAPNGVSCTMGPV 472
D+DEC G + +C N GSF C C G+ ++ + C GPV
Sbjct: 1764 PV-DIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPV 1817
Score = 52.0 bits (123), Expect = 2e-06
Identities = 72/320 (22%), Positives = 102/320 (31%), Gaps = 103/320 (32%)
Query: 248 FDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTC-----AS 302
++ S+G CV C N+ C GSF+C C GF DL TC
Sbjct: 754 YEVDSTGKNCVDINE-CVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECE 812
Query: 303 RNPCSSSPCRGG--------------------------ATC------------VLGPHGK 324
+PC + C+ TC + G K
Sbjct: 813 SSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLK 872
Query: 325 NYTCR------------------CPQGY-QLDSSQLDCVDVDECQDSPCAQE---CVNTP 362
+ C C +GY ++ +Q C D+DEC+ P + CVNT
Sbjct: 873 SQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQ--CEDIDECEVFPGVCKNGLCVNTR 930
Query: 363 GGFRCECWVGYEPGGPGEGACQDV-----------DECAL-------------------G 392
G F+C+C G G C D+ +EC L G
Sbjct: 931 GSFKCQCPSGMTLDATGR-ICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWG 989
Query: 393 RSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQ----CQDVDECVGPGGPLCDSLCFNTQG 448
C + + C G A ++ T +D++EC C NT G
Sbjct: 990 TEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIG 1049
Query: 449 SFHCGCLPGWVLAPNGVSCT 468
SF C C G+ L +CT
Sbjct: 1050 SFKCRCDSGFALDSEERNCT 1069
Score = 43.5 bits (101), Expect = 6e-04
Identities = 32/118 (27%), Positives = 46/118 (38%), Gaps = 24/118 (20%)
Query: 250 WGSSGPLCVSPKYGC------NFNNGGCHQ--DC------FEGGD-----GSFLCGCRPG 290
WG +C + + C N G C +C +GG+ GSF C C G
Sbjct: 217 WGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAG 276
Query: 291 FRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDV 346
+L + C + CS+ P C GG +Y C+CP G+ C+DV
Sbjct: 277 HKLNEVSQKCEDIDECSTIPGICEGGECTNTV---SSYFCKCPPGFYTSPDGTRCIDV 331
>gi|114431244 von Willebrand factor C and EGF domains [Homo sapiens]
Length = 955
Score = 142 bits (359), Expect = 7e-34
Identities = 105/301 (34%), Positives = 135/301 (44%), Gaps = 38/301 (12%)
Query: 300 CASRNPCSSSPCRGGATC-----VLGPHGKNYTCR----------CPQGYQLDSSQ--LD 342
C + N CS GATC G +G + TC CP G+ + + +
Sbjct: 80 CIAPNVCSCQDGEQGATCPETHGPCGEYGCDLTCNHGGCQEVARVCPVGFSMTETAVGIR 139
Query: 343 CVDVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTN 402
C D+DEC S C CVNT GGF CEC G + +CQD DEC LG +PC Q C N
Sbjct: 140 CTDIDECVTSSCEGHCVNTEGGFVCECGPGMQLSA-DRHSCQDTDEC-LG-TPCQQRCKN 196
Query: 403 TDGSFHCSCEEGYVLAGEDGTQCQDVDECVGP-GGPLCDSLCFNTQGSFHCGCLPGWVLA 461
+ GS+ CSC G+ L G + C DV+EC P +C C NT GSF C C PG+ L
Sbjct: 197 SIGSYKCSCRTGFHLHG-NRHSCVDVNECRRPLERRVCHHSCHNTVGSFLCTCRPGFRLR 255
Query: 462 PNGVSCTMGPVSLGPPSGPPDEEDKGEKEGSTVPRAATA------SPTRGPEGTPKATPT 515
+ VSC P ++ PS K +P A SP G G P T
Sbjct: 256 ADRVSCEAFPKAVLAPSAILQPRQHPSKMLLLLPEAGRPALSPGHSPPSGAPGPPAGVRT 315
Query: 516 TSRPSLSSDAPIT--SAPLKMLA-------PSGS-PGVWREPSIHHATAASGPQEPAGGD 565
T PS + P + SAP+ +L+ P+ S G R PS+ P P G +
Sbjct: 316 TRLPSPTPRLPTSSPSAPVWLLSTLLATPVPTASLLGNLRPPSLLQGEVMGTPSSPRGPE 375
Query: 566 S 566
S
Sbjct: 376 S 376
Score = 38.5 bits (88), Expect = 0.020
Identities = 111/468 (23%), Positives = 151/468 (32%), Gaps = 107/468 (22%)
Query: 161 SEGPCGSPGSPGSNIEGFVCKFSFKGMCRPLALGGPGQVTYTTPFQTTSSSLEAVP---- 216
+EG SP P N VC P GP Q TP QT + V
Sbjct: 451 AEGDVFSP--PNENCTVCVCLAGNVSCISPECPSGPCQ----TPPQTDCCTCVPVRCYFH 504
Query: 217 ---FASAANVACGEGDK--------DETQSHYFLCKEKAPDVFDWGSSGPLCV------S 259
+A A V G GD+ E + + C E A +W C +
Sbjct: 505 GRWYADGA-VFSGGGDECTTCVCQNGEVECSFMPCPELACPREEWRLGPGQCCFTCQEPT 563
Query: 260 PKYGCNFNNGGCH---QDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSS---PCR- 312
P GC+ ++ G + GD LC C+ D V+C R C S P R
Sbjct: 564 PSTGCSLDDNGVEFPIGQIWSPGDPCELCICQA-----DGSVSC-KRTDCVDSCPHPIRI 617
Query: 313 GGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQECVNTPGGFRCE---- 368
G C G YT R + S LD PC C+ G C
Sbjct: 618 PGQCCPDCSAGCTYTGRIFYNNETFPSVLD----------PCLS-CICLLGSVACSPVDC 666
Query: 369 ---CWVGYEPGGPGEGACQDVDE----------CALGRSPCAQGCTNTDGSFHC------ 409
C + P G C+D + L PC + CT G C
Sbjct: 667 PITCTYPFHPDGECCPVCRDCNYEGRKVANGQVFTLDDEPCTR-CTCQLGEVSCEKVPCQ 725
Query: 410 -SCEEGYVLAGEDGTQCQD----VDECVG--PGGPLC-----DSLCFNTQGSFHCGCLPG 457
+C + +L G+ + C D ++E G P G + SL +T+ +C PG
Sbjct: 726 RACADPALLPGDCCSSCPDSLSPLEEKQGLSPHGNVAFSKAGRSLHGDTEAPVNCSSCPG 785
Query: 458 ---------------WVLAPNGVSCTMGPVSLGPPSGPPDEEDKGEKEGSTVPRAATASP 502
+L N + P S P+G +T P ASP
Sbjct: 786 PPTASPSRPVLHLLQLLLRTNLMKTQTLPTS---PAGAHGPHSLALGLTATFPGEPGASP 842
Query: 503 TRGP-EGTPKATPTTSRPSLSSDAPITSAPLKMLAPSGSPGVWREPSI 549
P TP PT S + P P + + SG+ V R P +
Sbjct: 843 RLSPGPSTPPGAPTLPLASPGAPQPPPVTPERSFSASGAQIVSRWPPL 890
Score = 30.0 bits (66), Expect = 7.0
Identities = 21/63 (33%), Positives = 27/63 (42%), Gaps = 10/63 (15%)
Query: 450 FHCGCLPGWVLAPNGVSCTMGPVSLGPPSG----PPDEEDKGEKEGSTVPRAATASPTRG 505
F GC PGW + G CT+ S G SG P + ++G+T P T G
Sbjct: 49 FGSGCCPGWAPSMGGGHCTLPLCSFGCGSGICIAPNVCSCQDGEQGATCPE------THG 102
Query: 506 PEG 508
P G
Sbjct: 103 PCG 105
>gi|46249414 latent transforming growth factor beta binding protein 1
isoform LTBP-1L [Homo sapiens]
Length = 1722
Score = 140 bits (354), Expect = 3e-33
Identities = 76/196 (38%), Positives = 108/196 (55%), Gaps = 18/196 (9%)
Query: 280 DGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGK---NYTCRCPQGYQL 336
+GS++C C G+ D C + C G CV G ++ C C QGYQL
Sbjct: 1058 EGSYMCSCHKGYTRTPDHKHCRDIDECQQ-----GNLCVNGQCKNTEGSFRCTCGQGYQL 1112
Query: 337 DSSQLDCVDVDECQDSP-CAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRS 394
+++ C D+DECQ CA +C NT G F+C C GY G G+ C+D++EC +S
Sbjct: 1113 SAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDH-CEDINECLEDKS 1171
Query: 395 PCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLC--DSLCFNTQGSFH 451
C +G C NT GS+ C+C +G+ L +D CQD++EC PG LC C NT+GSFH
Sbjct: 1172 VCQRGDCINTAGSYDCTCPDGFQL--DDNKTCQDINECEHPG--LCGPQGECLNTEGSFH 1227
Query: 452 CGCLPGWVLAPNGVSC 467
C C G+ ++ +G +C
Sbjct: 1228 CVCQQGFSISADGRTC 1243
Score = 115 bits (288), Expect = 1e-25
Identities = 77/204 (37%), Positives = 102/204 (50%), Gaps = 18/204 (8%)
Query: 271 CHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCV--LGPHGKNYTC 328
C Q E +GSFLC C GF ++ C + C G CV +G Y
Sbjct: 927 CSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEY-- 984
Query: 329 RCPQGYQLDSSQLDCVDVDEC-QDSPCAQE-CVNTPGGFRC-ECWVGYEPGGPGEGACQD 385
C GY++ + + C D+DEC S C E CVN+PG ++C C G+ G C D
Sbjct: 985 -CDSGYRM-TQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFR---GWNGQCLD 1039
Query: 386 VDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLC-DSLC 443
VDEC L + CA G C+N +GS+ CSC +GY D C+D+DEC G LC + C
Sbjct: 1040 VDEC-LEPNVCANGDCSNLEGSYMCSCHKGYTRT-PDHKHCRDIDEC--QQGNLCVNGQC 1095
Query: 444 FNTQGSFHCGCLPGWVLAPNGVSC 467
NT+GSF C C G+ L+ C
Sbjct: 1096 KNTEGSFRCTCGQGYQLSAAKDQC 1119
Score = 102 bits (253), Expect = 1e-21
Identities = 68/197 (34%), Positives = 96/197 (48%), Gaps = 24/197 (12%)
Query: 281 GSFLCG-CRPGFRLL-----DDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGY 334
G+F C C G+R+ +D+ C + + C C + G C +G+
Sbjct: 978 GAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQC-------VNSPGSYQCVPCTEGF 1030
Query: 335 QLDSSQLDCVDVDEC-QDSPCAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALG 392
+ + Q C+DVDEC + + CA +C N G + C C GY P C+D+DEC G
Sbjct: 1031 RGWNGQ--CLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRT-PDHKHCRDIDECQQG 1087
Query: 393 RSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLC-DSLCFNTQGSF 450
C G C NT+GSF C+C +GY L+ QC+D+DEC LC C NT+GSF
Sbjct: 1088 NL-CVNGQCKNTEGSFRCTCGQGYQLSAAK-DQCEDIDEC--QHRHLCAHGQCRNTEGSF 1143
Query: 451 HCGCLPGWVLAPNGVSC 467
C C G+ + G C
Sbjct: 1144 QCVCDQGYRASGLGDHC 1160
Score = 98.2 bits (243), Expect = 2e-20
Identities = 61/156 (39%), Positives = 79/156 (50%), Gaps = 15/156 (9%)
Query: 304 NPCSSSP--CRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSP--CAQ-EC 358
N C+ +P C G C+ P YTC C +GY+ Q CVD+DEC C+Q C
Sbjct: 876 NECTVNPDIC-GAGHCINLP--VRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRC 932
Query: 359 VNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQG-CTNTDGSFHCS-CEEGYV 416
NT G F C C G+ G C DVDEC L C +G C NT G+F C C+ GY
Sbjct: 933 ENTEGSFLCICPAGFMASEEGTN-CIDVDEC-LRPDVCGEGHCVNTVGAFRCEYCDSGYR 990
Query: 417 LAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHC 452
+ +C+D+DEC+ P D C N+ GS+ C
Sbjct: 991 MTQRG--RCEDIDECLNP-STCPDEQCVNSPGSYQC 1023
Score = 69.7 bits (169), Expect = 8e-12
Identities = 74/260 (28%), Positives = 95/260 (36%), Gaps = 62/260 (23%)
Query: 267 NNGGCHQDCF-EGGDGSFLCGCRPGFRLLDDLVTCASRNPCS--SSPC--------RGGA 315
NN C F + GSF C C GF+ D C N C S C G
Sbjct: 1251 NNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSF 1310
Query: 316 TCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQD------------SPC--------- 354
CV + Y+ Q S+ LD VDVD+ ++ S C
Sbjct: 1311 LCVCADENQEYSPMTGQCRSRTSTDLD-VDVDQPKEEKKECYYNLNDASLCDNVLAPNVT 1369
Query: 355 AQECVNTPG---GFRCECWV-----------------GYEPGGPGEGAC-----QDVDEC 389
QEC T G G CE + G+ P G +D DEC
Sbjct: 1370 KQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADEC 1429
Query: 390 AL-GRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQ 447
L G+ C G C NT + C C++G QC D+DEC P + D C NT+
Sbjct: 1430 LLFGQEICKNGFCLNTRPGYECYCKQG-TYYDPVKLQCFDMDECQDPSSCI-DGQCVNTE 1487
Query: 448 GSFHCGCLPGWVLAPNGVSC 467
GS++C C VL + C
Sbjct: 1488 GSYNCFCTHPMVLDASEKRC 1507
Score = 57.4 bits (137), Expect = 4e-08
Identities = 30/71 (42%), Positives = 40/71 (56%), Gaps = 9/71 (12%)
Query: 311 CRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQD-----SPCAQ-ECVNTPGG 364
C G CV G YTC C GY LD++++ CVDV+EC + S C +C+NT G
Sbjct: 1632 CENGR-CVRVQEG--YTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGS 1688
Query: 365 FRCECWVGYEP 375
++C C GY P
Sbjct: 1689 YKCLCLPGYVP 1699
Score = 56.2 bits (134), Expect = 9e-08
Identities = 28/84 (33%), Positives = 41/84 (48%), Gaps = 2/84 (2%)
Query: 385 DVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLC 443
+++EC + C G C N + C C EGY + E +C D+DEC C
Sbjct: 874 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFS-EQQRKCVDIDECTQVQHLCSQGRC 932
Query: 444 FNTQGSFHCGCLPGWVLAPNGVSC 467
NT+GSF C C G++ + G +C
Sbjct: 933 ENTEGSFLCICPAGFMASEEGTNC 956
Score = 51.2 bits (121), Expect = 3e-06
Identities = 77/318 (24%), Positives = 105/318 (33%), Gaps = 69/318 (21%)
Query: 275 CFEGGDGSFLCGCRPGFRLLDDLV----TCASRNPCSSSPCRGGATCVLGPHGKNYTCRC 330
CF+ GS PG +D T N C P + HG N C
Sbjct: 559 CFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSY------HGYNQMMEC 612
Query: 331 PQGYQLDSSQLDCVDVDECQ-DSPCAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDVDE 388
GY+ ++ C D++ECQ C EC+NT G +RC C +G+ P D
Sbjct: 613 LPGYKRVNNTF-CQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPV 671
Query: 389 CALGRSPCAQGCTNTDGSFH----------CSCEEGYVLAGEDGTQCQDVDECVGPGGPL 438
+ + PC + ++ H C C G G C ++C PG
Sbjct: 672 ISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAW----GPHC---EKCPLPGTAA 724
Query: 439 CDSLCFNTQG------------SFHCGCLPGWVLAPNGVSCTMGPVSLGPPSGPPDEE-- 484
+C G H G P +V N S PP P EE
Sbjct: 725 FKEICPGGMGYTVSGVHRRRPIHHHVGKGPVFVKPKNTQPVAK---STHPPPLPAKEEPV 781
Query: 485 -----DKGEKEGSTVPRAATASP-----------TRGPEGTPKATPTTSRPSLSSDAP-- 526
+ G P ATA P T+ G P+ +P S L P
Sbjct: 782 EALTFSREHGPGVAEPEVATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPGI 841
Query: 527 ---ITSAPLKM-LAPSGS 540
TS P+ + +AP S
Sbjct: 842 VIEKTSPPVPVEVAPEAS 859
Score = 48.5 bits (114), Expect = 2e-05
Identities = 31/86 (36%), Positives = 43/86 (50%), Gaps = 6/86 (6%)
Query: 387 DECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDEC--VGPGGPLC-DSL 442
+EC + + C G C + C C +GY L T C DV+EC + LC ++
Sbjct: 1624 EECGI-LNGCENGRCVRVQEGYTCDCFDGYHLDTAKMT-CVDVNECDELNNRMSLCKNAK 1681
Query: 443 CFNTQGSFHCGCLPGWVLAPNGVSCT 468
C NT GS+ C CLPG+V + CT
Sbjct: 1682 CINTDGSYKCLCLPGYVPSDKPNYCT 1707
>gi|46249412 latent transforming growth factor beta binding protein
1 isoform LTBP-1S [Homo sapiens]
Length = 1396
Score = 140 bits (354), Expect = 3e-33
Identities = 76/196 (38%), Positives = 108/196 (55%), Gaps = 18/196 (9%)
Query: 280 DGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGK---NYTCRCPQGYQL 336
+GS++C C G+ D C + C G CV G ++ C C QGYQL
Sbjct: 732 EGSYMCSCHKGYTRTPDHKHCRDIDECQQ-----GNLCVNGQCKNTEGSFRCTCGQGYQL 786
Query: 337 DSSQLDCVDVDECQDSP-CAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRS 394
+++ C D+DECQ CA +C NT G F+C C GY G G+ C+D++EC +S
Sbjct: 787 SAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDH-CEDINECLEDKS 845
Query: 395 PCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLC--DSLCFNTQGSFH 451
C +G C NT GS+ C+C +G+ L +D CQD++EC PG LC C NT+GSFH
Sbjct: 846 VCQRGDCINTAGSYDCTCPDGFQL--DDNKTCQDINECEHPG--LCGPQGECLNTEGSFH 901
Query: 452 CGCLPGWVLAPNGVSC 467
C C G+ ++ +G +C
Sbjct: 902 CVCQQGFSISADGRTC 917
Score = 115 bits (288), Expect = 1e-25
Identities = 77/204 (37%), Positives = 102/204 (50%), Gaps = 18/204 (8%)
Query: 271 CHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCV--LGPHGKNYTC 328
C Q E +GSFLC C GF ++ C + C G CV +G Y
Sbjct: 601 CSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEY-- 658
Query: 329 RCPQGYQLDSSQLDCVDVDEC-QDSPCAQE-CVNTPGGFRC-ECWVGYEPGGPGEGACQD 385
C GY++ + + C D+DEC S C E CVN+PG ++C C G+ G C D
Sbjct: 659 -CDSGYRM-TQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFR---GWNGQCLD 713
Query: 386 VDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLC-DSLC 443
VDEC L + CA G C+N +GS+ CSC +GY D C+D+DEC G LC + C
Sbjct: 714 VDEC-LEPNVCANGDCSNLEGSYMCSCHKGYTRT-PDHKHCRDIDEC--QQGNLCVNGQC 769
Query: 444 FNTQGSFHCGCLPGWVLAPNGVSC 467
NT+GSF C C G+ L+ C
Sbjct: 770 KNTEGSFRCTCGQGYQLSAAKDQC 793
Score = 102 bits (253), Expect = 1e-21
Identities = 68/197 (34%), Positives = 96/197 (48%), Gaps = 24/197 (12%)
Query: 281 GSFLCG-CRPGFRLL-----DDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGY 334
G+F C C G+R+ +D+ C + + C C + G C +G+
Sbjct: 652 GAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQC-------VNSPGSYQCVPCTEGF 704
Query: 335 QLDSSQLDCVDVDEC-QDSPCAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALG 392
+ + Q C+DVDEC + + CA +C N G + C C GY P C+D+DEC G
Sbjct: 705 RGWNGQ--CLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRT-PDHKHCRDIDECQQG 761
Query: 393 RSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLC-DSLCFNTQGSF 450
C G C NT+GSF C+C +GY L+ QC+D+DEC LC C NT+GSF
Sbjct: 762 NL-CVNGQCKNTEGSFRCTCGQGYQLSAAK-DQCEDIDEC--QHRHLCAHGQCRNTEGSF 817
Query: 451 HCGCLPGWVLAPNGVSC 467
C C G+ + G C
Sbjct: 818 QCVCDQGYRASGLGDHC 834
Score = 98.2 bits (243), Expect = 2e-20
Identities = 61/156 (39%), Positives = 79/156 (50%), Gaps = 15/156 (9%)
Query: 304 NPCSSSP--CRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSP--CAQ-EC 358
N C+ +P C G C+ P YTC C +GY+ Q CVD+DEC C+Q C
Sbjct: 550 NECTVNPDIC-GAGHCINLP--VRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRC 606
Query: 359 VNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQG-CTNTDGSFHCS-CEEGYV 416
NT G F C C G+ G C DVDEC L C +G C NT G+F C C+ GY
Sbjct: 607 ENTEGSFLCICPAGFMASEEGTN-CIDVDEC-LRPDVCGEGHCVNTVGAFRCEYCDSGYR 664
Query: 417 LAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHC 452
+ +C+D+DEC+ P D C N+ GS+ C
Sbjct: 665 MTQRG--RCEDIDECLNP-STCPDEQCVNSPGSYQC 697
Score = 69.7 bits (169), Expect = 8e-12
Identities = 74/260 (28%), Positives = 95/260 (36%), Gaps = 62/260 (23%)
Query: 267 NNGGCHQDCF-EGGDGSFLCGCRPGFRLLDDLVTCASRNPCS--SSPC--------RGGA 315
NN C F + GSF C C GF+ D C N C S C G
Sbjct: 925 NNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSF 984
Query: 316 TCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQD------------SPC--------- 354
CV + Y+ Q S+ LD VDVD+ ++ S C
Sbjct: 985 LCVCADENQEYSPMTGQCRSRTSTDLD-VDVDQPKEEKKECYYNLNDASLCDNVLAPNVT 1043
Query: 355 AQECVNTPG---GFRCECWV-----------------GYEPGGPGEGAC-----QDVDEC 389
QEC T G G CE + G+ P G +D DEC
Sbjct: 1044 KQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADEC 1103
Query: 390 AL-GRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQ 447
L G+ C G C NT + C C++G QC D+DEC P + D C NT+
Sbjct: 1104 LLFGQEICKNGFCLNTRPGYECYCKQG-TYYDPVKLQCFDMDECQDPSSCI-DGQCVNTE 1161
Query: 448 GSFHCGCLPGWVLAPNGVSC 467
GS++C C VL + C
Sbjct: 1162 GSYNCFCTHPMVLDASEKRC 1181
Score = 57.4 bits (137), Expect = 4e-08
Identities = 30/71 (42%), Positives = 40/71 (56%), Gaps = 9/71 (12%)
Query: 311 CRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQD-----SPCAQ-ECVNTPGG 364
C G CV G YTC C GY LD++++ CVDV+EC + S C +C+NT G
Sbjct: 1306 CENGR-CVRVQEG--YTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGS 1362
Query: 365 FRCECWVGYEP 375
++C C GY P
Sbjct: 1363 YKCLCLPGYVP 1373
Score = 56.2 bits (134), Expect = 9e-08
Identities = 28/84 (33%), Positives = 41/84 (48%), Gaps = 2/84 (2%)
Query: 385 DVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLC 443
+++EC + C G C N + C C EGY + E +C D+DEC C
Sbjct: 548 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFS-EQQRKCVDIDECTQVQHLCSQGRC 606
Query: 444 FNTQGSFHCGCLPGWVLAPNGVSC 467
NT+GSF C C G++ + G +C
Sbjct: 607 ENTEGSFLCICPAGFMASEEGTNC 630
Score = 51.2 bits (121), Expect = 3e-06
Identities = 77/318 (24%), Positives = 105/318 (33%), Gaps = 69/318 (21%)
Query: 275 CFEGGDGSFLCGCRPGFRLLDDLV----TCASRNPCSSSPCRGGATCVLGPHGKNYTCRC 330
CF+ GS PG +D T N C P + HG N C
Sbjct: 233 CFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSY------HGYNQMMEC 286
Query: 331 PQGYQLDSSQLDCVDVDECQ-DSPCAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDVDE 388
GY+ ++ C D++ECQ C EC+NT G +RC C +G+ P D
Sbjct: 287 LPGYKRVNNTF-CQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPV 345
Query: 389 CALGRSPCAQGCTNTDGSFH----------CSCEEGYVLAGEDGTQCQDVDECVGPGGPL 438
+ + PC + ++ H C C G G C ++C PG
Sbjct: 346 ISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAW----GPHC---EKCPLPGTAA 398
Query: 439 CDSLCFNTQG------------SFHCGCLPGWVLAPNGVSCTMGPVSLGPPSGPPDEE-- 484
+C G H G P +V N S PP P EE
Sbjct: 399 FKEICPGGMGYTVSGVHRRRPIHHHVGKGPVFVKPKNTQPVAK---STHPPPLPAKEEPV 455
Query: 485 -----DKGEKEGSTVPRAATASP-----------TRGPEGTPKATPTTSRPSLSSDAP-- 526
+ G P ATA P T+ G P+ +P S L P
Sbjct: 456 EALTFSREHGPGVAEPEVATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPGI 515
Query: 527 ---ITSAPLKM-LAPSGS 540
TS P+ + +AP S
Sbjct: 516 VIEKTSPPVPVEVAPEAS 533
Score = 48.5 bits (114), Expect = 2e-05
Identities = 31/86 (36%), Positives = 43/86 (50%), Gaps = 6/86 (6%)
Query: 387 DECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDEC--VGPGGPLC-DSL 442
+EC + + C G C + C C +GY L T C DV+EC + LC ++
Sbjct: 1298 EECGI-LNGCENGRCVRVQEGYTCDCFDGYHLDTAKMT-CVDVNECDELNNRMSLCKNAK 1355
Query: 443 CFNTQGSFHCGCLPGWVLAPNGVSCT 468
C NT GS+ C CLPG+V + CT
Sbjct: 1356 CINTDGSYKCLCLPGYVPSDKPNYCT 1381
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 138 bits (347), Expect = 2e-32
Identities = 70/150 (46%), Positives = 87/150 (58%), Gaps = 6/150 (4%)
Query: 321 PHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQ-ECVNTPGGFRCECWVGYEPGGPG 379
P +Y C C GY+ D++ DC+DVDEC +PC +CVNTPG + C+C G++ P
Sbjct: 512 PTVSSYRCECNMGYKQDANG-DCIDVDECTSNPCTNGDCVNTPGSYYCKCHAGFQRT-PT 569
Query: 380 EGACQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPL 438
+ AC D+DEC C G C NTDGSF C C G+ L DG C D DEC L
Sbjct: 570 KQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELT-TDGKNCVDHDECTTTNMCL 628
Query: 439 CDSLCFNTQGSFHCGCLPGWVLAPNGVSCT 468
+ +C N GSF C C PG+VLAPNG CT
Sbjct: 629 -NGMCINEDGSFKCICKPGFVLAPNGRYCT 657
Score = 135 bits (339), Expect = 2e-31
Identities = 78/207 (37%), Positives = 106/207 (51%), Gaps = 17/207 (8%)
Query: 267 NNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGK 324
+N H C GSF C CR G+ + + + C + CS+ C A CV P
Sbjct: 1376 HNCDMHASCLNI-PGSFKCSCREGW--IGNGIKCIDLDECSNGTHQCSINAQCVNTPG-- 1430
Query: 325 NYTCRCPQGYQLDSSQLDCVDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPGEG 381
+Y C C +G+ D C DVDEC ++ C +C+N PG +RCEC +G+ P
Sbjct: 1431 SYRCACSEGFTGDG--FTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSR- 1487
Query: 382 ACQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCD 440
+CQD+DEC+ ++ C G C N G FHC C++GY L G C D+DEC P +
Sbjct: 1488 SCQDIDECSF-QNICVFGTCNNLPGMFHCICDDGYEL-DRTGGNCTDIDECADPIN-CVN 1544
Query: 441 SLCFNTQGSFHCGCLPGWVLAPNGVSC 467
LC NT G + C C P + L P GV C
Sbjct: 1545 GLCVNTPGRYECNCPPDFQLNPTGVGC 1571
Score = 130 bits (327), Expect = 4e-30
Identities = 76/211 (36%), Positives = 106/211 (50%), Gaps = 13/211 (6%)
Query: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRL-LDDLVTCASRNPCSSSP--CRGGATCVLG 320
C + C GSF C C G+ + C + C +P CRGG TCV
Sbjct: 1119 CRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGG-TCV-N 1176
Query: 321 PHGKNYTCRCPQGYQLDSSQLDCVDVDECQ--DSPCAQ-ECVNTPGGFRCECWVGYEPGG 377
G ++ C CP G++L S+ DCVD++EC D+ C +CVN G ++C C GY+
Sbjct: 1177 TEG-SFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQ-AT 1234
Query: 378 PGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGP 437
P C D+DEC + C CTN++GS+ CSC EGY L DG C D+DEC
Sbjct: 1235 PDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALM-PDGRSCADIDECEN-NPD 1292
Query: 438 LCD-SLCFNTQGSFHCGCLPGWVLAPNGVSC 467
+CD C N G + C C G++ + + +C
Sbjct: 1293 ICDGGQCTNIPGEYRCLCYDGFMASMDMKTC 1323
Score = 127 bits (320), Expect = 2e-29
Identities = 76/191 (39%), Positives = 104/191 (54%), Gaps = 14/191 (7%)
Query: 282 SFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQL 341
S+ C C G++ D C + C+S+PC G CV P +Y C+C G+Q ++
Sbjct: 516 SYRCECNMGYKQ-DANGDCIDVDECTSNPCTNG-DCVNTP--GSYYCKCHAGFQRTPTKQ 571
Query: 342 DCVDVDEC-QDSPCAQ--ECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQ 398
C+D+DEC Q+ + CVNT G F+C C G+E G+ C D DEC + C
Sbjct: 572 ACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKN-CVDHDECTT-TNMCLN 629
Query: 399 G-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLC-DSLCFNTQGSFHCGCLP 456
G C N DGSF C C+ G+VLA +G C DVDEC PG +C + C N++GSF C C P
Sbjct: 630 GMCINEDGSFKCICKPGFVLA-PNGRYCTDVDECQTPG--ICMNGHCINSEGSFRCDCPP 686
Query: 457 GWVLAPNGVSC 467
G + +G C
Sbjct: 687 GLAVGMDGRVC 697
Score = 124 bits (312), Expect = 2e-28
Identities = 85/265 (32%), Positives = 114/265 (43%), Gaps = 63/265 (23%)
Query: 250 WGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTC-ASRNPCSS 308
WG+ C PK G C + G L G RP ++ D+ C A C+
Sbjct: 1033 WGTECEEC--PKPGTKEYETLCPRGAGFANRGDVLTG-RPFYK---DINECKAFPGMCTY 1086
Query: 309 SPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSP--CAQE-CVNTPGGF 365
CR +G ++ CRC G+ LD + +C D+DEC+ SP C CVNTPG F
Sbjct: 1087 GKCRN----TIG----SFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSF 1138
Query: 366 RCECWVGYEPG------------------------------------------GPGEGAC 383
CEC+ GYE G P C
Sbjct: 1139 ECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDC 1198
Query: 384 QDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSL 442
D++EC+L + C G C N G++ CSC GY A D C D+DEC+ G CD+
Sbjct: 1199 VDINECSLSDNLCRNGKCVNMIGTYQCSCNPGY-QATPDRQGCTDIDECMIMNGG-CDTQ 1256
Query: 443 CFNTQGSFHCGCLPGWVLAPNGVSC 467
C N++GS+ C C G+ L P+G SC
Sbjct: 1257 CTNSEGSYECSCSEGYALMPDGRSC 1281
Score = 120 bits (302), Expect = 3e-27
Identities = 85/257 (33%), Positives = 110/257 (42%), Gaps = 28/257 (10%)
Query: 229 DKDETQSHYFLCKEKAPDVFDWGSSGPLC-----VSPKYGCNFNN------GGCHQDCFE 277
D DE + LC+ A + GS C +SP C N C
Sbjct: 1850 DIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCV 1909
Query: 278 GGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATC--VLGPHGKNYTCRCPQGYQ 335
GS+ C C GF+ D C + C PC G TC +G +Y C C G++
Sbjct: 1910 DLQGSYQCICHNGFKASQDQTMCMDVDECERHPC-GNGTCKNTVG----SYNCLCYPGFE 1964
Query: 336 LDSSQLDCVDVDECQD---SPCAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDVDECAL 391
L + DC+D+DEC C C N G F+C C GYE G+ C D +EC
Sbjct: 1965 LTHNN-DCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKN-CIDTNECVA 2022
Query: 392 GRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSF 450
C+ G C N +GSF C C GY + E+ C D++EC C NT G F
Sbjct: 2023 LPGSCSPGTCQNLEGSFRCICPPGYEVKSEN---CIDINECDEDPNICLFGSCTNTPGGF 2079
Query: 451 HCGCLPGWVLAPNGVSC 467
C C PG+VL+ NG C
Sbjct: 2080 QCLCPPGFVLSDNGRRC 2096
Score = 120 bits (301), Expect = 4e-27
Identities = 74/214 (34%), Positives = 106/214 (49%), Gaps = 20/214 (9%)
Query: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCS--SSPCRGGATCVLGP 321
C+ N+ C E GSF+C C+ G+ + C + C + C A+C+ P
Sbjct: 1329 CDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIP 1388
Query: 322 HGKNYTCRCPQGYQLDSSQLDCVDVDECQDSP--CA--QECVNTPGGFRCECWVGYEPGG 377
++ C C +G+ + + C+D+DEC + C+ +CVNTPG +RC C G+
Sbjct: 1389 G--SFKCSCREGWI--GNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFT--- 1441
Query: 378 PGEG-ACQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPG 435
G+G C DVDECA + C G C N G++ C CE G+ A D CQD+DEC
Sbjct: 1442 -GDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPAS-DSRSCQDIDECSFQN 1499
Query: 436 GPLCD-SLCFNTQGSFHCGCLPGWVLAPNGVSCT 468
+C C N G FHC C G+ L G +CT
Sbjct: 1500 --ICVFGTCNNLPGMFHCICDDGYELDRTGGNCT 1531
Score = 120 bits (300), Expect = 5e-27
Identities = 70/171 (40%), Positives = 88/171 (51%), Gaps = 14/171 (8%)
Query: 304 NPCSSSP--CRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQ-DSPCAQ-ECV 359
N C SP C G + G ++ C CP GY LD + + CVD DEC +PC C
Sbjct: 2173 NECLESPGICSNGQC--INTDG-SFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCT 2229
Query: 360 NTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAG 419
N G F C C G+EPG C+D++ECA CA C NT GS+ C+C GY L
Sbjct: 2230 NVIGSFECNCNEGFEPGPMMN--CEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALR- 2286
Query: 420 EDGTQCQDVDECVGPGGPLCDS---LCFNTQGSFHCGCLPGWVLAPNGVSC 467
ED C+D+DEC G C+S +C N G+F C C PG P+G C
Sbjct: 2287 EDQKMCKDLDEC-AEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGC 2336
Score = 120 bits (300), Expect = 5e-27
Identities = 67/191 (35%), Positives = 92/191 (48%), Gaps = 7/191 (3%)
Query: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQ 340
G F C C PGF C N C S P GA + +++C C +G+ LD++
Sbjct: 2552 GGFTCKCPPGFT--QHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATG 2609
Query: 341 LDCVDVDECQ-DSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQG 399
L+C DVDEC + C C N GG+RC C GY C D +EC+ + +
Sbjct: 2610 LNCEDVDECDGNHRCQHGCQNILGGYRCGCPQGYIQHYQW-NQCVDENECSNPNACGSAS 2668
Query: 400 CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWV 459
C NT GS+ C+C G+ + + C DV+EC P C+ C NT+G + CGC PG+
Sbjct: 2669 CYNTLGSYKCACPSGFSF-DQFSSACHDVNECSSSKNP-CNYGCSNTEGGYLCGCPPGYY 2726
Query: 460 LAPNGVSCTMG 470
G C G
Sbjct: 2727 RVGQG-HCVSG 2736
Score = 119 bits (298), Expect = 9e-27
Identities = 74/251 (29%), Positives = 102/251 (40%), Gaps = 54/251 (21%)
Query: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGAT----- 316
C NGGC C +GS+ C C G+ L+ D +CA + C ++P C GG
Sbjct: 1246 CMIMNGGCDTQC-TNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPG 1304
Query: 317 -------------------------------CVLGPHGK---NYTCRCPQGYQLDSSQLD 342
C+ G ++ C C GY +
Sbjct: 1305 EYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTG 1364
Query: 343 CVDVDECQ----DSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCA- 397
C DVDEC+ + C+N PG F+C C G+ G C D+DEC+ G C+
Sbjct: 1365 CTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGI---KCIDLDECSNGTHQCSI 1421
Query: 398 -QGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLP 456
C NT GS+ C+C EG+ DG C DVDEC + C N G++ C C
Sbjct: 1422 NAQCVNTPGSYRCACSEGFT---GDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEM 1478
Query: 457 GWVLAPNGVSC 467
G+ A + SC
Sbjct: 1479 GFTPASDSRSC 1489
Score = 115 bits (289), Expect = 1e-25
Identities = 89/246 (36%), Positives = 114/246 (46%), Gaps = 29/246 (11%)
Query: 226 GEGDKDETQSHYFLCKEKAPDVFDWGSSGPLCVSPKYGCN--FNNGGCHQDCFEGGDGSF 283
GEG DE + C+ K P + + G + S + CN F + +C + G
Sbjct: 2333 GEGCVDENE-----CRTK-PGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQG-- 2384
Query: 284 LCGCRPGFRLLDDLVTCASRNPCSSSPC-----RG-GATCVLGP--HGKNYTCRCPQGYQ 335
LC + + +SRN + S C RG G C L P Y CP G
Sbjct: 2385 LCFAEVLQTICQ--MASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHG-- 2440
Query: 336 LDSSQLDCVDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALG 392
D D+DEC+ P C +C+NT G FRC C VGY G +C D+DEC+
Sbjct: 2441 -PGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGT-SCIDLDECSQS 2498
Query: 393 RSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHC 452
PC C NT+GS+ CSC GYVL EDG C+D+DEC C LC NT G F C
Sbjct: 2499 PKPCNYICKNTEGSYQCSCPRGYVLQ-EDGKTCKDLDECQTKQHN-CQFLCVNTLGGFTC 2556
Query: 453 GCLPGW 458
C PG+
Sbjct: 2557 KCPPGF 2562
Score = 113 bits (283), Expect = 5e-25
Identities = 73/215 (33%), Positives = 103/215 (47%), Gaps = 25/215 (11%)
Query: 264 CNFNNGGCH----QDCFEGGDGSF--LCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGA 315
C +N G + C G F +CG PGF + C P C G
Sbjct: 1764 CTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICANGV 1823
Query: 316 TCV--LGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQ--DSPCAQ--ECVNTPGGFRCEC 369
C+ +G ++ C CP G+ + L C D+DEC D+ C + +C+N+PG +RCEC
Sbjct: 1824 -CINQIG----SFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCEC 1878
Query: 370 WVGYEPGGPGEGACQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDV 428
G++ GAC D +EC + C+ G C + GS+ C C G+ A +D T C DV
Sbjct: 1879 AAGFKLS--PNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGF-KASQDQTMCMDV 1935
Query: 429 DECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPN 463
DEC P + C NT GS++C C PG+ L N
Sbjct: 1936 DEC--ERHPCGNGTCKNTVGSYNCLCYPGFELTHN 1968
Score = 112 bits (280), Expect = 1e-24
Identities = 71/212 (33%), Positives = 100/212 (47%), Gaps = 16/212 (7%)
Query: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCS-SSPCRGGATC--VLG 320
C + G C DGSF C C G+ L V C + CS +PC G TC V+G
Sbjct: 2175 CLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPC-GNGTCTNVIG 2233
Query: 321 PHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSP--CAQECVNTPGGFRCECWVGYEPGGP 378
++ C C +G++ ++C D++EC +P CA C+NT G + C C +GY
Sbjct: 2234 ----SFECNCNEGFE-PGPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYAL-RE 2287
Query: 379 GEGACQDVDECALGRSPC---AQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPG 435
+ C+D+DECA G C C N G+F C C G + DG C D +EC
Sbjct: 2288 DQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPG-MARRPDGEGCVDENECRTKP 2346
Query: 436 GPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
G + C N GS+ C C G+ + +G C
Sbjct: 2347 GICENGRCVNIIGSYRCECNEGFQSSSSGTEC 2378
Score = 103 bits (256), Expect = 6e-22
Identities = 73/220 (33%), Positives = 102/220 (46%), Gaps = 39/220 (17%)
Query: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATC-VLGPHGKNYTCRCPQGYQLD 337
G+F+C C PG D C N C + P C G ++G +Y C C +G+Q
Sbjct: 2317 GTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIG----SYRCECNEGFQSS 2372
Query: 338 SSQLDCVDVDE-----------CQDSPCAQ------ECVNTPG---GFRCECW-----VG 372
SS +C+D + CQ + ++ EC G G +CE
Sbjct: 2373 SSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQ 2432
Query: 373 YE---PGGPGEGAC-QDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQD 427
Y+ P GPG +D+DEC + + C G C NT GSF C C+ GY GT C D
Sbjct: 2433 YKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYT-TDISGTSCID 2491
Query: 428 VDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
+DEC P C+ +C NT+GS+ C C G+VL +G +C
Sbjct: 2492 LDECSQSPKP-CNYICKNTEGSYQCSCPRGYVLQEDGKTC 2530
Score = 90.9 bits (224), Expect = 3e-18
Identities = 71/255 (27%), Positives = 101/255 (39%), Gaps = 48/255 (18%)
Query: 262 YGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVL 319
+G NG C + GSF C C G+ L D C N C + P C G L
Sbjct: 1981 FGQVCRNGRCFNEI-----GSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNL 2035
Query: 320 GPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSP---CAQECVNTPGGFRCECWVGYEPG 376
++ C CP GY++ S +C+D++EC + P C NTPGGF+C C G+
Sbjct: 2036 EG---SFRCICPPGYEVKSE--NCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLS 2090
Query: 377 GPGEGACQDVDE-----------CALGRS--------------------PCAQGCTNTDG 405
G C D + C++ ++ PC + +
Sbjct: 2091 DNGR-RCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEV 2149
Query: 406 SFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGV 465
+F C G+ +DV+EC+ G + C NT GSF C C G+ L GV
Sbjct: 2150 AFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGV 2209
Query: 466 SCT-MGPVSLGPPSG 479
C S+G P G
Sbjct: 2210 RCVDTDECSIGNPCG 2224
Score = 86.7 bits (213), Expect = 6e-17
Identities = 72/267 (26%), Positives = 96/267 (35%), Gaps = 84/267 (31%)
Query: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQ 340
G++ C C GF D +C + CS TC P + C C GY+LD +
Sbjct: 1470 GAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGTCNNLPG--MFHCICDDGYELDRTG 1527
Query: 341 LDCVDVDECQD-----------SPCAQECVNTPGGFR----------------------- 366
+C D+DEC D +P EC N P F+
Sbjct: 1528 GNCTDIDECADPINCVNGLCVNTPGRYEC-NCPPDFQLNPTGVGCVDNRVGNCYLKFGPR 1586
Query: 367 -------------------CECWVGYEPGGP------------------GEG-------- 381
C C +G G P GEG
Sbjct: 1587 GDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITI 1646
Query: 382 ACQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCD 440
+D+DEC C G C NT GSF C C +GY L+ ED C+D+DEC G
Sbjct: 1647 ILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLS-EDTRICEDIDECFAHPGVCGP 1705
Query: 441 SLCFNTQGSFHCGCLPGWVLAPNGVSC 467
C+NT G++ C C P ++ G +C
Sbjct: 1706 GTCYNTLGNYTCICPPEYMQVNGGHNC 1732
Score = 85.5 bits (210), Expect = 1e-16
Identities = 66/233 (28%), Positives = 93/233 (39%), Gaps = 38/233 (16%)
Query: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGF------RLLDDLVTC-ASRNPCSSSPCRGGAT 316
C + C E GS+ C C G+ R D+ C +R C + CR
Sbjct: 772 CALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPG 831
Query: 317 CVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQ-ECVNTPGGFRCECWVGYEP 375
+Y+C CP GY + C D++EC+ +PC C N G F CEC G +
Sbjct: 832 --------SYSCTCPPGYVFRTETETCEDINECESNPCVNGACRNNLGSFNCECSPGSKL 883
Query: 376 GGPG-------EGAC----QDVDECAL---GRSPCAQGCTNTDGSFHCSCEEGYV----- 416
G +G C QD C + G + ++ C ++ CE +
Sbjct: 884 SSTGLICIDSLKGTCWLNIQD-SRCEVNINGATLKSECCATLGAAWGSPCERCELDTACP 942
Query: 417 --LAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
LA G C+DV+EC G + C N++GSFHC C G L G C
Sbjct: 943 RGLARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVC 995
Score = 84.7 bits (208), Expect = 2e-16
Identities = 83/326 (25%), Positives = 110/326 (33%), Gaps = 102/326 (31%)
Query: 225 CGEGDKDETQSHYFL----------CKEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQD 274
C GD T Y+ K+ D+ + +G LC NG C
Sbjct: 544 CTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLC---------KNGRCVNT 594
Query: 275 CFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGY 334
DGSF C C GF L D C + C+++ C+ ++ C C G+
Sbjct: 595 -----DGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCI--NEDGSFKCICKPGF 647
Query: 335 QLDSSQLDCVDVDECQDSPCAQ--ECVNTPGGFRCECWVGYEPGGPG------------- 379
L + C DVDECQ C+N+ G FRC+C G G G
Sbjct: 648 VLAPNGRYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCY 707
Query: 380 ----EGACQDVDECALGRSPCAQGCTNTD---------------GSFH--CSCEEGYVLA 418
+G C A+ +S C C N D FH CS G +
Sbjct: 708 GGIKKGVCVRPFPGAVTKSECC--CANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVD 765
Query: 419 GED------------------------------------GTQCQDVDECVGPGGPLCDS- 441
G D G C D+DEC+ LCD+
Sbjct: 766 GRDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECL-VNRLLCDNG 824
Query: 442 LCFNTQGSFHCGCLPGWVLAPNGVSC 467
LC NT GS+ C C PG+V +C
Sbjct: 825 LCRNTPGSYSCTCPPGYVFRTETETC 850
Score = 82.0 bits (201), Expect = 2e-15
Identities = 68/202 (33%), Positives = 87/202 (43%), Gaps = 47/202 (23%)
Query: 298 VTCASRNPCSSSP--CRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDV--DECQDSP 353
VTC N C P C G CV ++ C CP+G LD + C+D+ ++C
Sbjct: 951 VTCEDVNECEVFPGVCPNGR-CVNSKG--SFHCECPEGLTLDGTGRVCLDIRMEQCYLKW 1007
Query: 354 CAQECVN-TPGGFR---CECWVG-----------------YE---PGG----------PG 379
EC++ PG FR C C VG YE P G G
Sbjct: 1008 DEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTG 1067
Query: 380 EGACQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDEC-VGPGGP 437
+D++EC C G C NT GSF C C G+ L E+ C D+DEC + P
Sbjct: 1068 RPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEE-RNCTDIDECRISP--D 1124
Query: 438 LCDS-LCFNTQGSFHCGCLPGW 458
LC S +C NT GSF C C G+
Sbjct: 1125 LCGSGICVNTPGSFECECFEGY 1146
Score = 78.6 bits (192), Expect = 2e-14
Identities = 68/225 (30%), Positives = 92/225 (40%), Gaps = 43/225 (19%)
Query: 271 CHQDCFEGGD-GSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCR 329
C C GG C C+ G+ + P + C+ G C+ GP+ C
Sbjct: 149 CSVRCMNGGTCADDHCQCQKGY------IGTYCGQPVCENGCQNGGRCI-GPN----RCA 197
Query: 330 CPQGYQLDSSQLDC--------VDVDECQDSPCAQECVNT--------PGGFRCE----- 368
C G+ + D V+ CQ C T G CE
Sbjct: 198 CVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCPAQ 257
Query: 369 ---CWVGYEPGGPGEGACQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQ 424
C G+ P GACQDVDEC C G C NT GSF C C G+ + E +
Sbjct: 258 PQPCRRGFIPN-IRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQS-ETTQK 315
Query: 425 CQDVDEC-VGPGGPLCDS-LCFNTQGSFHCGCLPGWVLAPNGVSC 467
C+D+DEC + PG +C++ C NT GS+ C C G+V + +G C
Sbjct: 316 CEDIDECSIIPG--ICETGECSNTVGSYFCVCPRGYVTSTDGSRC 358
Score = 58.9 bits (141), Expect = 1e-08
Identities = 58/213 (27%), Positives = 74/213 (34%), Gaps = 43/213 (20%)
Query: 284 LCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGKNYTCRCPQGYQLDSSQL 341
LC GFR + + C P C+GG C+ G ++ C CPQGY L
Sbjct: 1632 LCPGGEGFRPNPITIILEDIDECQELPGLCQGG-NCI-NTFG-SFQCECPQGYYLSEDTR 1688
Query: 342 DCVDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRS---- 394
C D+DEC P C C NT G + C C Y G C D+ + RS
Sbjct: 1689 ICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHN-CMDMRKSFCYRSYNGT 1747
Query: 395 ---------------------------PCAQGCTNTDGSFHCSCEE--GYVLAGEDGTQC 425
PC T F C G+ G +
Sbjct: 1748 TCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTG-KA 1806
Query: 426 QDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGW 458
D+DEC G + +C N GSF C C G+
Sbjct: 1807 VDIDECKEIPGICANGVCINQIGSFRCECPTGF 1839
Score = 56.6 bits (135), Expect = 7e-08
Identities = 44/138 (31%), Positives = 56/138 (40%), Gaps = 15/138 (10%)
Query: 287 CRPGFRLLDDLVTCASRNPCSSSP--CRGGATCV--LGPHGKNYTCRCPQGYQLDSSQLD 342
CR GF C + C + P C+GG C+ +G ++ CRCP G++ +
Sbjct: 261 CRRGFIPNIRTGACQDVDECQAIPGICQGG-NCINTVG----SFECRCPAGHKQSETTQK 315
Query: 343 CVDVDECQDSP--C-AQECVNTPGGFRCECWVGYEPGGPGEGAC-QDVDECALG--RSPC 396
C D+DEC P C EC NT G + C C GY G Q C G C
Sbjct: 316 CEDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLVNGRC 375
Query: 397 AQGCTNTDGSFHCSCEEG 414
AQ C CE G
Sbjct: 376 AQELPGRMTKMQCCCEPG 393
Score = 30.4 bits (67), Expect = 5.3
Identities = 19/68 (27%), Positives = 26/68 (38%), Gaps = 5/68 (7%)
Query: 224 ACGEGDKDETQSHYFLCKEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSF 283
ACG T Y K P F + C C+ + C+ C +G +
Sbjct: 2663 ACGSASCYNTLGSY---KCACPSGFSFDQFSSACHDVNE-CSSSKNPCNYGC-SNTEGGY 2717
Query: 284 LCGCRPGF 291
LCGC PG+
Sbjct: 2718 LCGCPPGY 2725
>gi|31377568 signal peptide, CUB domain, EGF-like 3 [Homo sapiens]
Length = 993
Score = 138 bits (347), Expect = 2e-32
Identities = 89/216 (41%), Positives = 104/216 (48%), Gaps = 23/216 (10%)
Query: 261 KYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDD----LVTCASRNPCSSSPCRGGAT 316
K CN+ NGGC C + G CGC F L D + TCA N S C AT
Sbjct: 198 KLTCNYGNGGCQHTCDDTEQGP-RCGCHIKFVLHTDGKTCIETCAVNNGGCDSKCHDAAT 256
Query: 317 CVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQ--DSPCAQECVNTPGGFRCECWVGYE 374
G H C CP G+ L + C D+DEC+ + C C NT G F C C GY+
Sbjct: 257 ---GVH-----CTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICRNTVGSFECSCKKGYK 308
Query: 375 PGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDEC-VG 433
E CQD+DEC+ R+ C C NT GSF C C GY+L G T C DVDEC +
Sbjct: 309 LL-INERNCQDIDECSFDRT-CDHICVNTPGSFQCLCHRGYLLYGI--THCGDVDECSIN 364
Query: 434 PGGPLCDSLCFNTQGSFHCGCLPG-WVLAPNGVSCT 468
GG C C NT GS+ C C G L NG CT
Sbjct: 365 RGG--CRFGCINTPGSYQCTCPAGQGRLHWNGKDCT 398
Score = 123 bits (309), Expect = 5e-28
Identities = 89/283 (31%), Positives = 116/283 (40%), Gaps = 29/283 (10%)
Query: 176 EGFVCKFSFKG---MCRPLALGG------PGQVTYTTPFQTTSSSLEAVPFASAANVACG 226
EG C G +CR GG PG F+ T + + + N C
Sbjct: 157 EGMNCMNKNHGCAHICRETPKGGIACECRPG-------FELTKNQRDCKLTCNYGNGGCQ 209
Query: 227 EGDKDETQSHYFLCKEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCG 286
D Q C K F + G C+ C NNGGC C + G C
Sbjct: 210 HTCDDTEQGPRCGCHIK----FVLHTDGKTCIET---CAVNNGGCDSKCHDAATGVH-CT 261
Query: 287 CRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDV 346
C GF L D TC + C + GG + ++ C C +GY+L ++ +C D+
Sbjct: 262 CPVGFMLQPDRKTCKDIDECRLN--NGGCDHICRNTVGSFECSCKKGYKLLINERNCQDI 319
Query: 347 DECQ-DSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDG 405
DEC D C CVNTPG F+C C GY G C DVDEC++ R C GC NT G
Sbjct: 320 DECSFDRTCDHICVNTPGSFQCLCHRGYLLYGITH--CGDVDECSINRGGCRFGCINTPG 377
Query: 406 SFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQG 448
S+ C+C G +G C + +C G G L N G
Sbjct: 378 SYQCTCPAGQGRLHWNGKDCTEPLKCQGSPGASKAMLSCNRSG 420
Score = 116 bits (291), Expect = 6e-26
Identities = 68/197 (34%), Positives = 88/197 (44%), Gaps = 8/197 (4%)
Query: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHG 323
C N GC C E G C CRPGF L + C + C+ TC G
Sbjct: 161 CMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCKLTCNYGNGGCQH--TCDDTEQG 218
Query: 324 KNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEGAC 383
C C + L + C++ + C +C + G C C VG+ P C
Sbjct: 219 PR--CGCHIKFVLHTDGKTCIETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQ-PDRKTC 275
Query: 384 QDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLC 443
+D+DEC L C C NT GSF CSC++GY L + CQD+DEC CD +C
Sbjct: 276 KDIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINE-RNCQDIDEC--SFDRTCDHIC 332
Query: 444 FNTQGSFHCGCLPGWVL 460
NT GSF C C G++L
Sbjct: 333 VNTPGSFQCLCHRGYLL 349
Score = 111 bits (277), Expect = 2e-24
Identities = 70/215 (32%), Positives = 96/215 (44%), Gaps = 25/215 (11%)
Query: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHG 323
C NGGC Q C GS+ C CR GF L D+ TC R G C+ HG
Sbjct: 116 CAEGNGGCQQSCVNMM-GSYECHCREGFFLSDNQHTCIQRP-------EEGMNCMNKNHG 167
Query: 324 KNYTCR----------CPQGYQLDSSQLDCVDVDECQDSPCAQECVNTPGGFRCECWVGY 373
+ CR C G++L +Q DC + C C +T G RC C + +
Sbjct: 168 CAHICRETPKGGIACECRPGFELTKNQRDCKLTCNYGNGGCQHTCDDTEQGPRCGCHIKF 227
Query: 374 EPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDEC-V 432
G+ ++ CA+ C C + HC+C G++L + T C+D+DEC +
Sbjct: 228 VLHTDGKTC---IETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRKT-CKDIDECRL 283
Query: 433 GPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
GG CD +C NT GSF C C G+ L N +C
Sbjct: 284 NNGG--CDHICRNTVGSFECSCKKGYKLLINERNC 316
Score = 107 bits (266), Expect = 4e-23
Identities = 61/166 (36%), Positives = 79/166 (47%), Gaps = 13/166 (7%)
Query: 311 CRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQ---DSPCAQECVNTPGGFRC 367
C A C P ++Y C C GY D C DVDEC+ ++ C +CVN PG +RC
Sbjct: 40 CHIDAICQNTP--RSYKCICKSGYTGDGKH--CKDVDECEREDNAGCVHDCVNIPGNYRC 95
Query: 368 ECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQD 427
C+ G+ G C DVDECA G C Q C N GS+ C C EG+ L+ T Q
Sbjct: 96 TCYDGFHLAHDGHN-CLDVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSDNQHTCIQR 154
Query: 428 VDE---CVGPGGPLCDSLCFNT-QGSFHCGCLPGWVLAPNGVSCTM 469
+E C+ C +C T +G C C PG+ L N C +
Sbjct: 155 PEEGMNCMNKNHG-CAHICRETPKGGIACECRPGFELTKNQRDCKL 199
Score = 92.8 bits (229), Expect = 9e-19
Identities = 53/133 (39%), Positives = 68/133 (51%), Gaps = 12/133 (9%)
Query: 345 DVDECQDSP--CAQE--CVNTPGGFRCECWVGYEPGGPGEGACQDVDECAL-GRSPCAQG 399
DVDEC + C + C NTP ++C C GY G C+DVDEC + C
Sbjct: 29 DVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDGKH---CKDVDECEREDNAGCVHD 85
Query: 400 CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECV-GPGGPLCDSLCFNTQGSFHCGCLPGW 458
C N G++ C+C +G+ LA DG C DVDEC G GG C C N GS+ C C G+
Sbjct: 86 CVNIPGNYRCTCYDGFHLA-HDGHNCLDVDECAEGNGG--CQQSCVNMMGSYECHCREGF 142
Query: 459 VLAPNGVSCTMGP 471
L+ N +C P
Sbjct: 143 FLSDNQHTCIQRP 155
Score = 68.6 bits (166), Expect = 2e-11
Identities = 36/88 (40%), Positives = 44/88 (50%), Gaps = 5/88 (5%)
Query: 382 ACQDVDECALGRSPCAQG--CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLC 439
A QDVDEC G C C NT S+ C C+ GY DG C+DVDEC C
Sbjct: 26 AAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYT---GDGKHCKDVDECEREDNAGC 82
Query: 440 DSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
C N G++ C C G+ LA +G +C
Sbjct: 83 VHDCVNIPGNYRCTCYDGFHLAHDGHNC 110
>gi|194328809 latent transforming growth factor beta binding protein
3 isoform 1 [Homo sapiens]
Length = 1303
Score = 137 bits (345), Expect = 3e-32
Identities = 87/202 (43%), Positives = 111/202 (54%), Gaps = 18/202 (8%)
Query: 275 CFEGGDGSFLCGCRPGFRLLDDLV--TCASRNPCSSSP-CRGGATCVLGPHGKNYTCRCP 331
C G GS+ C C G+RL +C N C+ C G C+ P +Y C C
Sbjct: 632 CMNTG-GSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPG--HYKCNCY 688
Query: 332 QGYQLDSSQLD-CVDVDECQD-SPCAQ-ECVNTPGGFRC-ECWVGYEPGGPGEGACQDVD 387
GY+L +S+ C D+DEC+D S C +C N PG F+C C GY G GAC+DV+
Sbjct: 689 PGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYR--SQGGGACRDVN 746
Query: 388 ECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDS-LCFN 445
ECA G SPC+ G C N GSF C+C +GY A DG C DVDEC G +CD+ +C N
Sbjct: 747 ECAEG-SPCSPGWCENLPGSFRCTCAQGYAPA-PDGRSCLDVDEC--EAGDVCDNGICSN 802
Query: 446 TQGSFHCGCLPGWVLAPNGVSC 467
T GSF C CL G+ L+ + C
Sbjct: 803 TPGSFQCQCLSGYHLSRDRSHC 824
Score = 117 bits (294), Expect = 3e-26
Identities = 71/206 (34%), Positives = 93/206 (45%), Gaps = 20/206 (9%)
Query: 271 CHQDCFEGGDGSFLC-GCRPGFR-----LLDDLVTCASRNPCSSSPCRGGATCVLGPHGK 324
C E GSF C C+PG+R D+ CA +PCS C
Sbjct: 713 CPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPG-------- 764
Query: 325 NYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQE--CVNTPGGFRCECWVGYEPGGPGEGA 382
++ C C QGY C+DVDEC+ C NTPG F+C+C GY
Sbjct: 765 SFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRD-RSH 823
Query: 383 CQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDEC-VGPGGPLCDS 441
C+D+DEC + C NT+GS+ C C +G+ L G G +CQD+DEC P L
Sbjct: 824 CEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVG--GRKCQDIDECSQDPSLCLPHG 881
Query: 442 LCFNTQGSFHCGCLPGWVLAPNGVSC 467
C N QGS+ C C G+ + C
Sbjct: 882 ACKNLQGSYVCVCDEGFTPTQDQHGC 907
Score = 116 bits (290), Expect = 7e-26
Identities = 98/302 (32%), Positives = 129/302 (42%), Gaps = 55/302 (18%)
Query: 196 PGQVTYTTPFQTTSSSL---EAVPFASAANVACGEGDKDETQSHYFLCKEKAPDVFDWGS 252
P QVT T + + E VP + C G + Q Y + + + G
Sbjct: 569 PTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNEC-EAEPCGP 627
Query: 253 SGPLCVSP--KYGCNFNNG----------------GCHQD--CFEGG-----DGSFLCGC 287
+C++ Y C+ N G C + C +GG G + C C
Sbjct: 628 GRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNC 687
Query: 288 RPGFRLLDDLVTCASRNPCSSS--PCRGGATCVLGPHGK------NYTC-RCPQGYQLDS 338
PG+RL ASR P CR ++C P GK ++ C C GY+
Sbjct: 688 YPGYRLK------ASRPPVCEDIDECRDPSSC---PDGKCENKPGSFKCIACQPGYRSQG 738
Query: 339 SQLDCVDVDECQD-SPCAQE-CVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPC 396
C DV+EC + SPC+ C N PG FRC C GY P G +C DVDEC G C
Sbjct: 739 GGA-CRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGR-SCLDVDECEAG-DVC 795
Query: 397 AQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCL 455
G C+NT GSF C C GY L+ D + C+D+DEC P + C NT GS+ C C
Sbjct: 796 DNGICSNTPGSFQCQCLSGYHLS-RDRSHCEDIDECDFPAACIGGD-CINTNGSYRCLCP 853
Query: 456 PG 457
G
Sbjct: 854 QG 855
Score = 105 bits (261), Expect = 2e-22
Identities = 63/175 (36%), Positives = 80/175 (45%), Gaps = 11/175 (6%)
Query: 313 GGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQE---CVNTPGGFRCEC 369
G CV GP +Y+C C GY+ CVDV+EC+ PC C+NT G + C C
Sbjct: 586 GHGECVPGP--PDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHC 643
Query: 370 WVGYE-PGGPGEGACQDVDECALGRSPCAQG--CTNTDGSFHCSCEEGYVLAGEDGTQCQ 426
GY G G +C D++ECA C G C N G + C+C GY L C+
Sbjct: 644 NRGYRLHVGAGGRSCVDLNECAKPHL-CGDGGFCINFPGHYKCNCYPGYRLKASRPPVCE 702
Query: 427 DVDECVGPGGPLCDSLCFNTQGSFHC-GCLPGWVLAPNGVSCTMGPVSLGPPSGP 480
D+DEC P D C N GSF C C PG+ G + + G P P
Sbjct: 703 DIDECRDPSS-CPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSP 756
Score = 94.0 bits (232), Expect = 4e-19
Identities = 60/192 (31%), Positives = 88/192 (45%), Gaps = 24/192 (12%)
Query: 257 CVSPKYGCNFNNGGCHQD---CFEGGD----------GSFLCGCRPGFRLLDDLVTCASR 303
C++ + G GG +D C EG GSF C C G+ D +C
Sbjct: 727 CIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDV 786
Query: 304 NPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCA---QECVN 360
+ C + C P ++ C+C GY L + C D+DEC D P A +C+N
Sbjct: 787 DECEAGDVCDNGICSNTPG--SFQCQCLSGYHLSRDRSHCEDIDEC-DFPAACIGGDCIN 843
Query: 361 TPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQ--GCTNTDGSFHCSCEEGYVLA 418
T G +RC C G+ G + CQD+DEC+ S C C N GS+ C C+EG+
Sbjct: 844 TNGSYRCLCPQGHRLVGGRK--CQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFT-P 900
Query: 419 GEDGTQCQDVDE 430
+D C++V++
Sbjct: 901 TQDQHGCEEVEQ 912
Score = 78.2 bits (191), Expect = 2e-14
Identities = 62/173 (35%), Positives = 77/173 (44%), Gaps = 17/173 (9%)
Query: 308 SSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQD-SPCAQ-ECVNTPGGF 365
S C+ G CV G Y C C QG+ D + L+CVDVDEC D S C C NT GG+
Sbjct: 1002 SEICKEGK-CVNTQPG--YECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGY 1058
Query: 366 RCECWVGYEPGGPGEGAC-----QDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAG 419
RC C E P + C DVDEC + C G C N GS+ C C +V G
Sbjct: 1059 RCACTPPAE-YSPAQRQCLSPEEMDVDECQ-DPAACRPGRCVNLPGSYRCECRPPWV-PG 1115
Query: 420 EDGTQCQDVDECVGPGGPLCDSLCFNTQG--SFHCGCLPGWVLAPNGVSCTMG 470
G CQ + E P +C++ +G G L G L + C G
Sbjct: 1116 PSGRDCQ-LPESPAERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQG 1167
Score = 65.9 bits (159), Expect = 1e-10
Identities = 71/236 (30%), Positives = 91/236 (38%), Gaps = 39/236 (16%)
Query: 285 CGCRPGFRLLDDLVTCASRNPC-SSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDC 343
C C+ GF +L+ C + C S CR G V Y C C + +Q C
Sbjct: 1019 CYCKQGFYYDGNLLECVDVDECLDESNCRNG---VCENTRGGYRCACTPPAEYSPAQRQC 1075
Query: 344 -----VDVDECQDSPCAQ--ECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPC 396
+DVDECQD + CVN PG +RCEC + PG G +C L SP
Sbjct: 1076 LSPEEMDVDECQDPAACRPGRCVNLPGSYRCECRPPWVPGPSGR-------DCQLPESPA 1128
Query: 397 AQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECV---GPG-GPLCDSLCFNTQGSFHC 452
+ D + E+G + AG D+C G G G C GS HC
Sbjct: 1129 ERAPERRDVCWSQRGEDG-MCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGS-HC 1186
Query: 453 GCLPGWVLAPNGVSCTMGPVSLGPPSGPPDEEDKGEKE--------GSTVPRAATA 500
P N T P+ LG PP +ED E++ G VPR A
Sbjct: 1187 ---PTSQSESNSFWDT-SPLLLGK---PPRDEDSSEEDSDECRCVSGRCVPRPGGA 1235
Score = 63.5 bits (153), Expect = 6e-10
Identities = 37/83 (44%), Positives = 44/83 (53%), Gaps = 10/83 (12%)
Query: 308 SSPCRG-GATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSP-----CAQE-CVN 360
S CR CV P G C CP G+QLD+S+ CVD+DEC++ C E CVN
Sbjct: 1218 SDECRCVSGRCVPRPGGA--VCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVN 1275
Query: 361 TPGGFRCECWVGYEPGGPGEGAC 383
T G FRC C G+ P GAC
Sbjct: 1276 TSGSFRCVCKAGFARSRP-HGAC 1297
Score = 50.4 bits (119), Expect = 5e-06
Identities = 30/83 (36%), Positives = 39/83 (46%), Gaps = 9/83 (10%)
Query: 345 DVDECQDSPCAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDVDECA----LGRSPCAQG 399
D DEC+ C CV PGG CEC G++ C D+DEC G ++
Sbjct: 1217 DSDECR---CVSGRCVPRPGGAVCECPGGFQLDA-SRARCVDIDECRELNQRGLLCKSER 1272
Query: 400 CTNTDGSFHCSCEEGYVLAGEDG 422
C NT GSF C C+ G+ + G
Sbjct: 1273 CVNTSGSFRCVCKAGFARSRPHG 1295
Score = 47.0 bits (110), Expect = 6e-05
Identities = 32/86 (37%), Positives = 40/86 (46%), Gaps = 11/86 (12%)
Query: 384 QDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDEC--VGPGGPLCD 440
+D DEC C G C G C C G+ L +C D+DEC + G LC
Sbjct: 1216 EDSDECR-----CVSGRCVPRPGGAVCECPGGFQLDASRA-RCVDIDECRELNQRGLLCK 1269
Query: 441 S-LCFNTQGSFHCGCLPGWVLA-PNG 464
S C NT GSF C C G+ + P+G
Sbjct: 1270 SERCVNTSGSFRCVCKAGFARSRPHG 1295
Score = 46.6 bits (109), Expect = 7e-05
Identities = 24/64 (37%), Positives = 31/64 (48%), Gaps = 5/64 (7%)
Query: 405 GSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLC-DSLCFNTQGSFHCGCLPGWVLAPN 463
G C +GY + T CQD++EC PG +C C N GS+ C C PG L P+
Sbjct: 335 GEVGADCPQGYKRL--NSTHCQDINECAMPG--VCRHGDCLNNPGSYRCVCPPGHSLGPS 390
Query: 464 GVSC 467
C
Sbjct: 391 RTQC 394
Score = 42.4 bits (98), Expect = 0.001
Identities = 59/221 (26%), Positives = 80/221 (36%), Gaps = 34/221 (15%)
Query: 320 GPHGKNYTCRCPQGYQLDSSQLDCVDVDEC-QDSPCAQ-ECVNTPGGFRCECWVGYEPGG 377
GP CPQGY+ +S C D++EC C +C+N PG +RC C G+ G
Sbjct: 331 GPVRGEVGADCPQGYKRLNST-HCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSL-G 388
Query: 378 PGEGAC-----QDVDECALGRSP---CAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVD 429
P C ++ C SP C T C C G G +CQ
Sbjct: 389 PSRTQCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAW----GARCQ--- 441
Query: 430 ECVGPGGPLCDSLC-----FNTQGSFHCGCLPG-----WVLAPNGVSCTMGPVSL-GPPS 478
C G +C ++ S + G L P+G P L PS
Sbjct: 442 RCPTDGTAAFKEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDG---PPKPQQLPESPS 498
Query: 479 GPPDEEDKGEKEGSTVPRAATASPTRGPEGTPKATPTTSRP 519
P ED E+ G T + + + P AT T +RP
Sbjct: 499 QAPPPEDTEEERGVTTD-SPVSEERSVQQSHPTATTTPARP 538
>gi|18497288 latent transforming growth factor beta binding protein
3 isoform 2 [Homo sapiens]
Length = 1256
Score = 137 bits (345), Expect = 3e-32
Identities = 87/202 (43%), Positives = 111/202 (54%), Gaps = 18/202 (8%)
Query: 275 CFEGGDGSFLCGCRPGFRLLDDLV--TCASRNPCSSSP-CRGGATCVLGPHGKNYTCRCP 331
C G GS+ C C G+RL +C N C+ C G C+ P +Y C C
Sbjct: 632 CMNTG-GSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPG--HYKCNCY 688
Query: 332 QGYQLDSSQLD-CVDVDECQD-SPCAQ-ECVNTPGGFRC-ECWVGYEPGGPGEGACQDVD 387
GY+L +S+ C D+DEC+D S C +C N PG F+C C GY G GAC+DV+
Sbjct: 689 PGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYR--SQGGGACRDVN 746
Query: 388 ECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDS-LCFN 445
ECA G SPC+ G C N GSF C+C +GY A DG C DVDEC G +CD+ +C N
Sbjct: 747 ECAEG-SPCSPGWCENLPGSFRCTCAQGYAPA-PDGRSCLDVDEC--EAGDVCDNGICSN 802
Query: 446 TQGSFHCGCLPGWVLAPNGVSC 467
T GSF C CL G+ L+ + C
Sbjct: 803 TPGSFQCQCLSGYHLSRDRSHC 824
Score = 117 bits (294), Expect = 3e-26
Identities = 71/206 (34%), Positives = 93/206 (45%), Gaps = 20/206 (9%)
Query: 271 CHQDCFEGGDGSFLC-GCRPGFR-----LLDDLVTCASRNPCSSSPCRGGATCVLGPHGK 324
C E GSF C C+PG+R D+ CA +PCS C
Sbjct: 713 CPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPG-------- 764
Query: 325 NYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQE--CVNTPGGFRCECWVGYEPGGPGEGA 382
++ C C QGY C+DVDEC+ C NTPG F+C+C GY
Sbjct: 765 SFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRD-RSH 823
Query: 383 CQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDEC-VGPGGPLCDS 441
C+D+DEC + C NT+GS+ C C +G+ L G G +CQD+DEC P L
Sbjct: 824 CEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVG--GRKCQDIDECSQDPSLCLPHG 881
Query: 442 LCFNTQGSFHCGCLPGWVLAPNGVSC 467
C N QGS+ C C G+ + C
Sbjct: 882 ACKNLQGSYVCVCDEGFTPTQDQHGC 907
Score = 116 bits (290), Expect = 7e-26
Identities = 98/302 (32%), Positives = 129/302 (42%), Gaps = 55/302 (18%)
Query: 196 PGQVTYTTPFQTTSSSL---EAVPFASAANVACGEGDKDETQSHYFLCKEKAPDVFDWGS 252
P QVT T + + E VP + C G + Q Y + + + G
Sbjct: 569 PTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNEC-EAEPCGP 627
Query: 253 SGPLCVSP--KYGCNFNNG----------------GCHQD--CFEGG-----DGSFLCGC 287
+C++ Y C+ N G C + C +GG G + C C
Sbjct: 628 GRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNC 687
Query: 288 RPGFRLLDDLVTCASRNPCSSS--PCRGGATCVLGPHGK------NYTC-RCPQGYQLDS 338
PG+RL ASR P CR ++C P GK ++ C C GY+
Sbjct: 688 YPGYRLK------ASRPPVCEDIDECRDPSSC---PDGKCENKPGSFKCIACQPGYRSQG 738
Query: 339 SQLDCVDVDECQD-SPCAQE-CVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPC 396
C DV+EC + SPC+ C N PG FRC C GY P G +C DVDEC G C
Sbjct: 739 GGA-CRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGR-SCLDVDECEAG-DVC 795
Query: 397 AQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCL 455
G C+NT GSF C C GY L+ D + C+D+DEC P + C NT GS+ C C
Sbjct: 796 DNGICSNTPGSFQCQCLSGYHLS-RDRSHCEDIDECDFPAACIGGD-CINTNGSYRCLCP 853
Query: 456 PG 457
G
Sbjct: 854 QG 855
Score = 105 bits (261), Expect = 2e-22
Identities = 63/175 (36%), Positives = 80/175 (45%), Gaps = 11/175 (6%)
Query: 313 GGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQE---CVNTPGGFRCEC 369
G CV GP +Y+C C GY+ CVDV+EC+ PC C+NT G + C C
Sbjct: 586 GHGECVPGP--PDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHC 643
Query: 370 WVGYE-PGGPGEGACQDVDECALGRSPCAQG--CTNTDGSFHCSCEEGYVLAGEDGTQCQ 426
GY G G +C D++ECA C G C N G + C+C GY L C+
Sbjct: 644 NRGYRLHVGAGGRSCVDLNECAKPHL-CGDGGFCINFPGHYKCNCYPGYRLKASRPPVCE 702
Query: 427 DVDECVGPGGPLCDSLCFNTQGSFHC-GCLPGWVLAPNGVSCTMGPVSLGPPSGP 480
D+DEC P D C N GSF C C PG+ G + + G P P
Sbjct: 703 DIDECRDPSS-CPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSP 756
Score = 94.0 bits (232), Expect = 4e-19
Identities = 60/192 (31%), Positives = 88/192 (45%), Gaps = 24/192 (12%)
Query: 257 CVSPKYGCNFNNGGCHQD---CFEGGD----------GSFLCGCRPGFRLLDDLVTCASR 303
C++ + G GG +D C EG GSF C C G+ D +C
Sbjct: 727 CIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDV 786
Query: 304 NPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCA---QECVN 360
+ C + C P ++ C+C GY L + C D+DEC D P A +C+N
Sbjct: 787 DECEAGDVCDNGICSNTPG--SFQCQCLSGYHLSRDRSHCEDIDEC-DFPAACIGGDCIN 843
Query: 361 TPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQ--GCTNTDGSFHCSCEEGYVLA 418
T G +RC C G+ G + CQD+DEC+ S C C N GS+ C C+EG+
Sbjct: 844 TNGSYRCLCPQGHRLVGGRK--CQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFT-P 900
Query: 419 GEDGTQCQDVDE 430
+D C++V++
Sbjct: 901 TQDQHGCEEVEQ 912
Score = 63.5 bits (153), Expect = 6e-10
Identities = 37/83 (44%), Positives = 44/83 (53%), Gaps = 10/83 (12%)
Query: 308 SSPCRG-GATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSP-----CAQE-CVN 360
S CR CV P G C CP G+QLD+S+ CVD+DEC++ C E CVN
Sbjct: 1171 SDECRCVSGRCVPRPGGA--VCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVN 1228
Query: 361 TPGGFRCECWVGYEPGGPGEGAC 383
T G FRC C G+ P GAC
Sbjct: 1229 TSGSFRCVCKAGFARSRP-HGAC 1250
Score = 55.1 bits (131), Expect = 2e-07
Identities = 65/219 (29%), Positives = 82/219 (37%), Gaps = 58/219 (26%)
Query: 308 SSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQD-SPCAQ-ECVNTPGGF 365
S C+ G CV G Y C C QG+ D + L+CVDVDEC D S C C NT GG+
Sbjct: 1002 SEICKEGK-CVNTQPG--YECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGY 1058
Query: 366 RCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQC 425
RC C E P + C +E + R+P + + + GEDG
Sbjct: 1059 RCACTPPAE-YSPAQRQCLSPEE--MERAPERR-------------DVCWSQRGEDGM-- 1100
Query: 426 QDVDECVGP-GGPLC--DSLCFNTQGSFHCGCLPGWVLAPNGVSC-------------TM 469
C GP GP D C + C P P G
Sbjct: 1101 -----CAGPLAGPALTFDDCCCRQGRGWGAQCRP---CPPRGAGSHCPTSQSESNSFWDT 1152
Query: 470 GPVSLGPPSGPPDEEDKGEKE--------GSTVPRAATA 500
P+ LG PP +ED E++ G VPR A
Sbjct: 1153 SPLLLGK---PPRDEDSSEEDSDECRCVSGRCVPRPGGA 1188
Score = 52.0 bits (123), Expect = 2e-06
Identities = 59/235 (25%), Positives = 80/235 (34%), Gaps = 60/235 (25%)
Query: 285 CGCRPGFRLLDDLVTCASRNPC-SSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDC 343
C C+ GF +L+ C + C S CR G V Y C C + +Q C
Sbjct: 1019 CYCKQGFYYDGNLLECVDVDECLDESNCRNG---VCENTRGGYRCACTPPAEYSPAQRQC 1075
Query: 344 VDVDECQDSP---------------CAQE-----------CVNTPGGFRCECWVGYEPGG 377
+ +E + +P CA C G+ +C P G
Sbjct: 1076 LSPEEMERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQC-RPCPPRG 1134
Query: 378 PG---------EGACQDVDECALGRSP--------------CAQG-CTNTDGSFHCSCEE 413
G + D LG+ P C G C G C C
Sbjct: 1135 AGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCVSGRCVPRPGGAVCECPG 1194
Query: 414 GYVLAGEDGTQCQDVDEC--VGPGGPLCDS-LCFNTQGSFHCGCLPGWVLA-PNG 464
G+ L +C D+DEC + G LC S C NT GSF C C G+ + P+G
Sbjct: 1195 GFQL-DASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHG 1248
Score = 46.6 bits (109), Expect = 7e-05
Identities = 24/64 (37%), Positives = 31/64 (48%), Gaps = 5/64 (7%)
Query: 405 GSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLC-DSLCFNTQGSFHCGCLPGWVLAPN 463
G C +GY + T CQD++EC PG +C C N GS+ C C PG L P+
Sbjct: 335 GEVGADCPQGYKRL--NSTHCQDINECAMPG--VCRHGDCLNNPGSYRCVCPPGHSLGPS 390
Query: 464 GVSC 467
C
Sbjct: 391 RTQC 394
Score = 42.4 bits (98), Expect = 0.001
Identities = 59/221 (26%), Positives = 80/221 (36%), Gaps = 34/221 (15%)
Query: 320 GPHGKNYTCRCPQGYQLDSSQLDCVDVDEC-QDSPCAQ-ECVNTPGGFRCECWVGYEPGG 377
GP CPQGY+ +S C D++EC C +C+N PG +RC C G+ G
Sbjct: 331 GPVRGEVGADCPQGYKRLNST-HCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSL-G 388
Query: 378 PGEGAC-----QDVDECALGRSP---CAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVD 429
P C ++ C SP C T C C G G +CQ
Sbjct: 389 PSRTQCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAW----GARCQ--- 441
Query: 430 ECVGPGGPLCDSLC-----FNTQGSFHCGCLPG-----WVLAPNGVSCTMGPVSL-GPPS 478
C G +C ++ S + G L P+G P L PS
Sbjct: 442 RCPTDGTAAFKEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDG---PPKPQQLPESPS 498
Query: 479 GPPDEEDKGEKEGSTVPRAATASPTRGPEGTPKATPTTSRP 519
P ED E+ G T + + + P AT T +RP
Sbjct: 499 QAPPPEDTEEERGVTTD-SPVSEERSVQQSHPTATTTPARP 538
>gi|110347437 latent transforming growth factor beta binding protein
4 isoform c [Homo sapiens]
Length = 1557
Score = 137 bits (344), Expect = 4e-32
Identities = 82/225 (36%), Positives = 102/225 (45%), Gaps = 15/225 (6%)
Query: 251 GSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSP 310
G G C C C + GSF C C GFR C + C+ SP
Sbjct: 634 GFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSP 693
Query: 311 CRGGATCVLGPHGK---NYTCRCPQGYQLDSSQLDCVDVDECQDSPCA--QECVNTPGGF 365
C G ++ C CP G+Q +++ +C DVDEC++ QECVN+PG F
Sbjct: 694 ----PPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSF 749
Query: 366 RCE-CWVGYEPGGPGEGACQDVDECALGRSPCAQG--CTNTDGSFHCSCEEGYVLAGEDG 422
+C C G+ G C DVDEC+ G PC CTNT+GSF CSC GY
Sbjct: 750 QCRTCPSGHHLH---RGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRP 806
Query: 423 TQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
C DV+EC+ C NT GSF C C PG+ P G SC
Sbjct: 807 GPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC 851
Score = 134 bits (338), Expect = 2e-31
Identities = 81/198 (40%), Positives = 91/198 (45%), Gaps = 16/198 (8%)
Query: 277 EGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGK---NYTCRCPQG 333
E GSF C C PGFR C + C P C LG ++ C CP G
Sbjct: 537 ENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVP----PPCDLGRCENTPGSFLCVCPAG 592
Query: 334 YQLDSSQLDCVDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDVDECA 390
YQ C DVDEC SP C + C N PG FRC C G+ G +DVDECA
Sbjct: 593 YQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFR----GSACEEDVDECA 648
Query: 391 LGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGS 449
PC G C NT GSFHC+C G+ G G CQDVDEC P C NT+GS
Sbjct: 649 QEPPPCGPGRCDNTAGSFHCACPAGFRSRGP-GAPCQDVDECARSPPPCTYGRCENTEGS 707
Query: 450 FHCGCLPGWVLAPNGVSC 467
F C C G+ G C
Sbjct: 708 FQCVCPMGFQPNTAGSEC 725
Score = 124 bits (311), Expect = 3e-28
Identities = 91/245 (37%), Positives = 112/245 (45%), Gaps = 28/245 (11%)
Query: 277 EGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGKNYTCRCPQGY 334
E GSFLC C G++ +C + C+ SP C GA C P ++ C CP G+
Sbjct: 579 ENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGA-CKNLPG--SFRCVCPAGF 635
Query: 335 QLDSSQLDCVDVDEC--QDSPCAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDVDECAL 391
+ + + DVDEC + PC C NT G F C C G+ GPG CQDVDECA
Sbjct: 636 RGSACE---EDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPG-APCQDVDECAR 691
Query: 392 GRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVG----PGGPLCDSLCFNT 446
PC G C NT+GSF C C G+ G++C+DVDEC PG C N+
Sbjct: 692 SPPPCTYGRCENTEGSFQCVCPMGFQ-PNTAGSECEDVDECENHLACPGQE-----CVNS 745
Query: 447 QGSFHCGCLPGWVLAPNGVSCTMGPVSLG-PPSGPPDEEDKGEKEGSTVPRAATASPTRG 505
GSF C P G + S G PP GP EGS R + A R
Sbjct: 746 PGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGP--HGHCTNTEGSF--RCSCAPGYRA 801
Query: 506 PEGTP 510
P G P
Sbjct: 802 PSGRP 806
Score = 122 bits (307), Expect = 8e-28
Identities = 77/185 (41%), Positives = 86/185 (46%), Gaps = 19/185 (10%)
Query: 303 RNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQ--DSPCAQ-ECV 359
RNP P R C+ P G YTC C G++L C+DVDEC+ PCA C
Sbjct: 484 RNPQVCGPGR----CISRPSG--YTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCE 537
Query: 360 NTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLA 418
N+PG FRC C G+ GP C DVDEC PC G C NT GSF C C GY A
Sbjct: 538 NSPGSFRCVCGPGFR-AGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGY-QA 595
Query: 419 GEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGW---VLAPNGVSCTMGPVSLG 475
G CQDVDEC G C N GSF C C G+ + C P
Sbjct: 596 APHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEP---- 651
Query: 476 PPSGP 480
PP GP
Sbjct: 652 PPCGP 656
Score = 122 bits (307), Expect = 8e-28
Identities = 101/283 (35%), Positives = 117/283 (41%), Gaps = 34/283 (12%)
Query: 271 CHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSS--PCRGGATCVLGPHGKNYTC 328
C DGSF C C PG R DL +C + C G C P
Sbjct: 863 CQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVR 922
Query: 329 RCPQGYQLDSSQLDCVDVDECQD---SPC-AQECVNTPGGFRCE--CWVGYEPGGPGEGA 382
C GY + C DVDECQ+ C AQ C NTPG +RC C GY+P PG G
Sbjct: 923 DCDPGYHA-GPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPT-PG-GG 979
Query: 383 CQDVDECALGRSPCAQG--CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCD 440
CQDVDEC RS C C N GSF C C++GY A DG C DV+EC G
Sbjct: 980 CQDVDECR-NRSFCGAHAVCQNLPGSFQCLCDQGYEGA-RDGRHCVDVNECETLQGVCGA 1037
Query: 441 SLCFNTQGSFHCGCLPGWVLAPNGVSCTMGPVSLGPPSG--PPDEEDKGEKEGSTVPRAA 498
+LC N +GSF C C PN P P +G P G GS A
Sbjct: 1038 ALCENVEGSFLCVC-------PN------SPEEFDPMTGRCVPPRTSAGTFPGS--QPQA 1082
Query: 499 TASPTRGPEGTPKATPTTSRPSLSSDAPITSAPLKMLAPSGSP 541
ASP P P RPS P+ S + + +P
Sbjct: 1083 PASPVL--PARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAP 1123
Score = 122 bits (306), Expect = 1e-27
Identities = 87/246 (35%), Positives = 113/246 (45%), Gaps = 39/246 (15%)
Query: 235 SHYFLCKEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLL 294
S + L + + DV + S P C G H C +GSF C C PG+R
Sbjct: 756 SGHHLHRGRCTDVDECSSGAPPC------------GPHGHC-TNTEGSFRCSCAPGYR-- 800
Query: 295 DDLVTCASRNPCSS-SPCRGGATCVLGPHGK------NYTCRCPQGYQLDSSQLDCVDVD 347
PC+ + C G C PHG+ ++ C C GY+ C+DVD
Sbjct: 801 ---APSGRPGPCADVNECLEGDFCF--PHGECLNTDGSFACTCAPGYRPGPRGASCLDVD 855
Query: 348 ECQDSPCAQE--CVNTPGGFRCECWVGYEPGGPGEGACQDVDEC-ALGRSPC-AQGCTNT 403
EC + Q C NT G F C C G+ GP +C DVDEC G + C +Q C N+
Sbjct: 856 ECSEEDLCQSGICTNTDGSFECICPPGHR-AGPDLASCLDVDECRERGPALCGSQRCENS 914
Query: 404 DGSFHC--SCEEGYVLAGEDGTQCQDVDECVGPGGPLCDS-LCFNTQGSFHC--GCLPGW 458
GS+ C C+ GY AG +GT C DVDEC G +C + C NT GS+ C C PG+
Sbjct: 915 PGSYRCVRDCDPGY-HAGPEGT-CDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGY 972
Query: 459 VLAPNG 464
P G
Sbjct: 973 QPTPGG 978
Score = 90.1 bits (222), Expect = 6e-18
Identities = 52/123 (42%), Positives = 62/123 (50%), Gaps = 6/123 (4%)
Query: 349 CQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQG-CTNTD 404
CQ +P C C++ P G+ C C G+ G C DVDEC PCA G C N+
Sbjct: 482 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGT-RCIDVDECRRVPPPCAPGRCENSP 540
Query: 405 GSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNG 464
GSF C C G+ AG +C DVDEC P C NT GSF C C G+ AP+G
Sbjct: 541 GSFRCVCGPGF-RAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHG 599
Query: 465 VSC 467
SC
Sbjct: 600 ASC 602
Score = 65.1 bits (157), Expect = 2e-10
Identities = 60/173 (34%), Positives = 73/173 (42%), Gaps = 27/173 (15%)
Query: 320 GPHGKNYTCRCP--QGYQLDSSQLDCV-DVDECQ---DSPCAQE-CVNTPGGFRCECWVG 372
G Y CP +GY S L DVDECQ D C CVNT G+ C C G
Sbjct: 1158 GTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNG 1217
Query: 373 YEPGGPGEGACQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGED----GTQCQD 427
Y C D DECA C G C NT GS+HC+CE VL G + Q
Sbjct: 1218 YYYHTQ-RLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQS 1276
Query: 428 VDECVG-----PGGPL-CDSLCFNTQGSF-HCGCLPG--WVLAPNGVSCTMGP 471
+D+ +G G L C + Q ++ C CL G W G+ C + P
Sbjct: 1277 LDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAW-----GMDCALCP 1324
Score = 62.0 bits (149), Expect = 2e-09
Identities = 30/71 (42%), Positives = 41/71 (57%), Gaps = 9/71 (12%)
Query: 311 CRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQ------ECVNTPGG 364
C G CV P G +TCRC GY+LD +++ CVD++EC ++ A C+NT G
Sbjct: 1476 CTNGR-CVRVPEG--FTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGS 1532
Query: 365 FRCECWVGYEP 375
FRC C G+ P
Sbjct: 1533 FRCICRPGFAP 1543
Score = 57.4 bits (137), Expect = 4e-08
Identities = 69/249 (27%), Positives = 88/249 (35%), Gaps = 39/249 (15%)
Query: 345 DVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQG-CTNT 403
D C + E V+ P G C G+E G+C+DVDECA G C G C NT
Sbjct: 256 DCQLCSERLGNSERVSAPDG---PCPTGFERVN---GSCEDVDECATG-GRCQHGECANT 308
Query: 404 DGSFHCSCEEGYVLAGEDGTQCQD--VDECVGPGGPLCDSLCFNTQGSFHCG-------- 453
G + C C +G++L + + E GP CF C
Sbjct: 309 RGGYTCVCPDGFLLDSSRSSCISQHVISEAKGP--------CFRVLRDGGCSLPILRNIT 360
Query: 454 ---CLPGWVLAPNGVSCTMGPV--SLG----PPSGPPDEEDKGEKEGSTVPRAATASPTR 504
C V G C + P S G P+GP + +T P P R
Sbjct: 361 KQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLG--QEPPR 418
Query: 505 GPEGTPKATPTTSRPSLSSDAPITSAPLKMLAPSGSPGVWREPSIHHATAASGPQEPAGG 564
P+ P TSRPS P P PG E + A +GP+ P G
Sbjct: 419 VSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPG--PELPLPSIPAWTGPEIPESG 476
Query: 565 DSSVATQNN 573
SS Q N
Sbjct: 477 PSSGMCQRN 485
Score = 56.6 bits (135), Expect = 7e-08
Identities = 45/125 (36%), Positives = 52/125 (41%), Gaps = 9/125 (7%)
Query: 343 CVDVDECQDSPCA-QECVNTPGG---FRCECWVGYEPGGPGEGACQDVDECALGRSP-CA 397
C V E S C Q+C T C GY +DVDEC L R C
Sbjct: 1140 CCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCK 1199
Query: 398 QG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDS-LCFNTQGSFHCGCL 455
G C NT + C C GY + +C D DEC P C+ C NT GS+HC C
Sbjct: 1200 SGVCVNTAPGYSCYCSNGYYYHTQR-LECIDNDECADEE-PACEGGRCVNTVGSYHCTCE 1257
Query: 456 PGWVL 460
P VL
Sbjct: 1258 PPLVL 1262
Score = 53.9 bits (128), Expect = 5e-07
Identities = 35/99 (35%), Positives = 47/99 (47%), Gaps = 10/99 (10%)
Query: 321 PHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGE 380
P G +Y + Y+ ++ +C +D C + CV P GF C C+ GY
Sbjct: 1449 PEGGSYAGSLAEPYEELEAE-ECGILDGCTNG----RCVRVPEGFTCRCFDGYRLDMT-R 1502
Query: 381 GACQDVDEC--ALGRSP-CAQG-CTNTDGSFHCSCEEGY 415
AC D++EC A SP C C NTDGSF C C G+
Sbjct: 1503 MACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGF 1541
Score = 51.2 bits (121), Expect = 3e-06
Identities = 24/62 (38%), Positives = 31/62 (50%), Gaps = 6/62 (9%)
Query: 311 CRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQE---CVNTPGGFRC 367
C+ G P Y+C C GY + +L+C+D DEC D A E CVNT G + C
Sbjct: 1198 CKSGVCVNTAP---GYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHC 1254
Query: 368 EC 369
C
Sbjct: 1255 TC 1256
Score = 49.3 bits (116), Expect = 1e-05
Identities = 31/81 (38%), Positives = 39/81 (48%), Gaps = 14/81 (17%)
Query: 383 CQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQ--CQDVDEC--VGPGGPL 438
C +D C GR C F C C +GY L D T+ C D++EC PL
Sbjct: 1470 CGILDGCTNGR------CVRVPEGFTCRCFDGYRL---DMTRMACVDINECDEAEAASPL 1520
Query: 439 C-DSLCFNTQGSFHCGCLPGW 458
C ++ C NT GSF C C PG+
Sbjct: 1521 CVNARCLNTDGSFRCICRPGF 1541
Score = 39.3 bits (90), Expect = 0.012
Identities = 28/91 (30%), Positives = 41/91 (45%), Gaps = 10/91 (10%)
Query: 379 GEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQ--CQDVDECVGPGG 436
G G V +C L C++ N++ S +G G + C+DVDEC GG
Sbjct: 247 GAGLAWGVHDCQL----CSERLGNSE---RVSAPDGPCPTGFERVNGSCEDVDECA-TGG 298
Query: 437 PLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
C NT+G + C C G++L + SC
Sbjct: 299 RCQHGECANTRGGYTCVCPDGFLLDSSRSSC 329
>gi|110347412 latent transforming growth factor beta binding protein
4 isoform b [Homo sapiens]
Length = 1587
Score = 137 bits (344), Expect = 4e-32
Identities = 82/225 (36%), Positives = 102/225 (45%), Gaps = 15/225 (6%)
Query: 251 GSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSP 310
G G C C C + GSF C C GFR C + C+ SP
Sbjct: 664 GFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSP 723
Query: 311 CRGGATCVLGPHGK---NYTCRCPQGYQLDSSQLDCVDVDECQDSPCA--QECVNTPGGF 365
C G ++ C CP G+Q +++ +C DVDEC++ QECVN+PG F
Sbjct: 724 ----PPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSF 779
Query: 366 RCE-CWVGYEPGGPGEGACQDVDECALGRSPCAQG--CTNTDGSFHCSCEEGYVLAGEDG 422
+C C G+ G C DVDEC+ G PC CTNT+GSF CSC GY
Sbjct: 780 QCRTCPSGHHLH---RGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRP 836
Query: 423 TQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
C DV+EC+ C NT GSF C C PG+ P G SC
Sbjct: 837 GPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC 881
Score = 134 bits (338), Expect = 2e-31
Identities = 81/198 (40%), Positives = 91/198 (45%), Gaps = 16/198 (8%)
Query: 277 EGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGK---NYTCRCPQG 333
E GSF C C PGFR C + C P C LG ++ C CP G
Sbjct: 567 ENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVP----PPCDLGRCENTPGSFLCVCPAG 622
Query: 334 YQLDSSQLDCVDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDVDECA 390
YQ C DVDEC SP C + C N PG FRC C G+ G +DVDECA
Sbjct: 623 YQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFR----GSACEEDVDECA 678
Query: 391 LGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGS 449
PC G C NT GSFHC+C G+ G G CQDVDEC P C NT+GS
Sbjct: 679 QEPPPCGPGRCDNTAGSFHCACPAGFRSRGP-GAPCQDVDECARSPPPCTYGRCENTEGS 737
Query: 450 FHCGCLPGWVLAPNGVSC 467
F C C G+ G C
Sbjct: 738 FQCVCPMGFQPNTAGSEC 755
Score = 124 bits (311), Expect = 3e-28
Identities = 91/245 (37%), Positives = 112/245 (45%), Gaps = 28/245 (11%)
Query: 277 EGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGKNYTCRCPQGY 334
E GSFLC C G++ +C + C+ SP C GA C P ++ C CP G+
Sbjct: 609 ENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGA-CKNLPG--SFRCVCPAGF 665
Query: 335 QLDSSQLDCVDVDEC--QDSPCAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDVDECAL 391
+ + + DVDEC + PC C NT G F C C G+ GPG CQDVDECA
Sbjct: 666 RGSACE---EDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPG-APCQDVDECAR 721
Query: 392 GRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVG----PGGPLCDSLCFNT 446
PC G C NT+GSF C C G+ G++C+DVDEC PG C N+
Sbjct: 722 SPPPCTYGRCENTEGSFQCVCPMGFQ-PNTAGSECEDVDECENHLACPGQE-----CVNS 775
Query: 447 QGSFHCGCLPGWVLAPNGVSCTMGPVSLG-PPSGPPDEEDKGEKEGSTVPRAATASPTRG 505
GSF C P G + S G PP GP EGS R + A R
Sbjct: 776 PGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGP--HGHCTNTEGSF--RCSCAPGYRA 831
Query: 506 PEGTP 510
P G P
Sbjct: 832 PSGRP 836
Score = 122 bits (307), Expect = 8e-28
Identities = 77/185 (41%), Positives = 86/185 (46%), Gaps = 19/185 (10%)
Query: 303 RNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQ--DSPCAQ-ECV 359
RNP P R C+ P G YTC C G++L C+DVDEC+ PCA C
Sbjct: 514 RNPQVCGPGR----CISRPSG--YTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCE 567
Query: 360 NTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLA 418
N+PG FRC C G+ GP C DVDEC PC G C NT GSF C C GY A
Sbjct: 568 NSPGSFRCVCGPGFR-AGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGY-QA 625
Query: 419 GEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGW---VLAPNGVSCTMGPVSLG 475
G CQDVDEC G C N GSF C C G+ + C P
Sbjct: 626 APHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEP---- 681
Query: 476 PPSGP 480
PP GP
Sbjct: 682 PPCGP 686
Score = 122 bits (307), Expect = 8e-28
Identities = 101/283 (35%), Positives = 117/283 (41%), Gaps = 34/283 (12%)
Query: 271 CHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSS--PCRGGATCVLGPHGKNYTC 328
C DGSF C C PG R DL +C + C G C P
Sbjct: 893 CQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVR 952
Query: 329 RCPQGYQLDSSQLDCVDVDECQD---SPC-AQECVNTPGGFRCE--CWVGYEPGGPGEGA 382
C GY + C DVDECQ+ C AQ C NTPG +RC C GY+P PG G
Sbjct: 953 DCDPGYHA-GPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPT-PG-GG 1009
Query: 383 CQDVDECALGRSPCAQG--CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCD 440
CQDVDEC RS C C N GSF C C++GY A DG C DV+EC G
Sbjct: 1010 CQDVDECR-NRSFCGAHAVCQNLPGSFQCLCDQGYEGA-RDGRHCVDVNECETLQGVCGA 1067
Query: 441 SLCFNTQGSFHCGCLPGWVLAPNGVSCTMGPVSLGPPSG--PPDEEDKGEKEGSTVPRAA 498
+LC N +GSF C C PN P P +G P G GS A
Sbjct: 1068 ALCENVEGSFLCVC-------PN------SPEEFDPMTGRCVPPRTSAGTFPGS--QPQA 1112
Query: 499 TASPTRGPEGTPKATPTTSRPSLSSDAPITSAPLKMLAPSGSP 541
ASP P P RPS P+ S + + +P
Sbjct: 1113 PASPVL--PARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAP 1153
Score = 122 bits (306), Expect = 1e-27
Identities = 87/246 (35%), Positives = 113/246 (45%), Gaps = 39/246 (15%)
Query: 235 SHYFLCKEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLL 294
S + L + + DV + S P C G H C +GSF C C PG+R
Sbjct: 786 SGHHLHRGRCTDVDECSSGAPPC------------GPHGHC-TNTEGSFRCSCAPGYR-- 830
Query: 295 DDLVTCASRNPCSS-SPCRGGATCVLGPHGK------NYTCRCPQGYQLDSSQLDCVDVD 347
PC+ + C G C PHG+ ++ C C GY+ C+DVD
Sbjct: 831 ---APSGRPGPCADVNECLEGDFCF--PHGECLNTDGSFACTCAPGYRPGPRGASCLDVD 885
Query: 348 ECQDSPCAQE--CVNTPGGFRCECWVGYEPGGPGEGACQDVDEC-ALGRSPC-AQGCTNT 403
EC + Q C NT G F C C G+ GP +C DVDEC G + C +Q C N+
Sbjct: 886 ECSEEDLCQSGICTNTDGSFECICPPGHR-AGPDLASCLDVDECRERGPALCGSQRCENS 944
Query: 404 DGSFHC--SCEEGYVLAGEDGTQCQDVDECVGPGGPLCDS-LCFNTQGSFHC--GCLPGW 458
GS+ C C+ GY AG +GT C DVDEC G +C + C NT GS+ C C PG+
Sbjct: 945 PGSYRCVRDCDPGY-HAGPEGT-CDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGY 1002
Query: 459 VLAPNG 464
P G
Sbjct: 1003 QPTPGG 1008
Score = 90.1 bits (222), Expect = 6e-18
Identities = 52/123 (42%), Positives = 62/123 (50%), Gaps = 6/123 (4%)
Query: 349 CQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQG-CTNTD 404
CQ +P C C++ P G+ C C G+ G C DVDEC PCA G C N+
Sbjct: 512 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGT-RCIDVDECRRVPPPCAPGRCENSP 570
Query: 405 GSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNG 464
GSF C C G+ AG +C DVDEC P C NT GSF C C G+ AP+G
Sbjct: 571 GSFRCVCGPGF-RAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHG 629
Query: 465 VSC 467
SC
Sbjct: 630 ASC 632
Score = 65.1 bits (157), Expect = 2e-10
Identities = 60/173 (34%), Positives = 73/173 (42%), Gaps = 27/173 (15%)
Query: 320 GPHGKNYTCRCP--QGYQLDSSQLDCV-DVDECQ---DSPCAQE-CVNTPGGFRCECWVG 372
G Y CP +GY S L DVDECQ D C CVNT G+ C C G
Sbjct: 1188 GTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNG 1247
Query: 373 YEPGGPGEGACQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGED----GTQCQD 427
Y C D DECA C G C NT GS+HC+CE VL G + Q
Sbjct: 1248 YYYHTQ-RLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQS 1306
Query: 428 VDECVG-----PGGPL-CDSLCFNTQGSF-HCGCLPG--WVLAPNGVSCTMGP 471
+D+ +G G L C + Q ++ C CL G W G+ C + P
Sbjct: 1307 LDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAW-----GMDCALCP 1354
Score = 62.0 bits (149), Expect = 2e-09
Identities = 30/71 (42%), Positives = 41/71 (57%), Gaps = 9/71 (12%)
Query: 311 CRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQ------ECVNTPGG 364
C G CV P G +TCRC GY+LD +++ CVD++EC ++ A C+NT G
Sbjct: 1506 CTNGR-CVRVPEG--FTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGS 1562
Query: 365 FRCECWVGYEP 375
FRC C G+ P
Sbjct: 1563 FRCICRPGFAP 1573
Score = 57.4 bits (137), Expect = 4e-08
Identities = 69/249 (27%), Positives = 88/249 (35%), Gaps = 39/249 (15%)
Query: 345 DVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQG-CTNT 403
D C + E V+ P G C G+E G+C+DVDECA G C G C NT
Sbjct: 286 DCQLCSERLGNSERVSAPDG---PCPTGFERVN---GSCEDVDECATG-GRCQHGECANT 338
Query: 404 DGSFHCSCEEGYVLAGEDGTQCQD--VDECVGPGGPLCDSLCFNTQGSFHCG-------- 453
G + C C +G++L + + E GP CF C
Sbjct: 339 RGGYTCVCPDGFLLDSSRSSCISQHVISEAKGP--------CFRVLRDGGCSLPILRNIT 390
Query: 454 ---CLPGWVLAPNGVSCTMGPV--SLG----PPSGPPDEEDKGEKEGSTVPRAATASPTR 504
C V G C + P S G P+GP + +T P P R
Sbjct: 391 KQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLG--QEPPR 448
Query: 505 GPEGTPKATPTTSRPSLSSDAPITSAPLKMLAPSGSPGVWREPSIHHATAASGPQEPAGG 564
P+ P TSRPS P P PG E + A +GP+ P G
Sbjct: 449 VSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPG--PELPLPSIPAWTGPEIPESG 506
Query: 565 DSSVATQNN 573
SS Q N
Sbjct: 507 PSSGMCQRN 515
Score = 56.6 bits (135), Expect = 7e-08
Identities = 45/125 (36%), Positives = 52/125 (41%), Gaps = 9/125 (7%)
Query: 343 CVDVDECQDSPCA-QECVNTPGG---FRCECWVGYEPGGPGEGACQDVDECALGRSP-CA 397
C V E S C Q+C T C GY +DVDEC L R C
Sbjct: 1170 CCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCK 1229
Query: 398 QG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDS-LCFNTQGSFHCGCL 455
G C NT + C C GY + +C D DEC P C+ C NT GS+HC C
Sbjct: 1230 SGVCVNTAPGYSCYCSNGYYYHTQR-LECIDNDECADEE-PACEGGRCVNTVGSYHCTCE 1287
Query: 456 PGWVL 460
P VL
Sbjct: 1288 PPLVL 1292
Score = 53.9 bits (128), Expect = 5e-07
Identities = 35/99 (35%), Positives = 47/99 (47%), Gaps = 10/99 (10%)
Query: 321 PHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGE 380
P G +Y + Y+ ++ +C +D C + CV P GF C C+ GY
Sbjct: 1479 PEGGSYAGSLAEPYEELEAE-ECGILDGCTNG----RCVRVPEGFTCRCFDGYRLDMT-R 1532
Query: 381 GACQDVDEC--ALGRSP-CAQG-CTNTDGSFHCSCEEGY 415
AC D++EC A SP C C NTDGSF C C G+
Sbjct: 1533 MACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGF 1571
Score = 51.2 bits (121), Expect = 3e-06
Identities = 24/62 (38%), Positives = 31/62 (50%), Gaps = 6/62 (9%)
Query: 311 CRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQE---CVNTPGGFRC 367
C+ G P Y+C C GY + +L+C+D DEC D A E CVNT G + C
Sbjct: 1228 CKSGVCVNTAP---GYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHC 1284
Query: 368 EC 369
C
Sbjct: 1285 TC 1286
Score = 49.3 bits (116), Expect = 1e-05
Identities = 31/81 (38%), Positives = 39/81 (48%), Gaps = 14/81 (17%)
Query: 383 CQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQ--CQDVDEC--VGPGGPL 438
C +D C GR C F C C +GY L D T+ C D++EC PL
Sbjct: 1500 CGILDGCTNGR------CVRVPEGFTCRCFDGYRL---DMTRMACVDINECDEAEAASPL 1550
Query: 439 C-DSLCFNTQGSFHCGCLPGW 458
C ++ C NT GSF C C PG+
Sbjct: 1551 CVNARCLNTDGSFRCICRPGF 1571
Score = 39.3 bits (90), Expect = 0.012
Identities = 28/91 (30%), Positives = 41/91 (45%), Gaps = 10/91 (10%)
Query: 379 GEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQ--CQDVDECVGPGG 436
G G V +C L C++ N++ S +G G + C+DVDEC GG
Sbjct: 277 GAGLAWGVHDCQL----CSERLGNSE---RVSAPDGPCPTGFERVNGSCEDVDECA-TGG 328
Query: 437 PLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
C NT+G + C C G++L + SC
Sbjct: 329 RCQHGECANTRGGYTCVCPDGFLLDSSRSSC 359
>gi|110347431 latent transforming growth factor beta binding protein
4 isoform a [Homo sapiens]
Length = 1624
Score = 137 bits (344), Expect = 4e-32
Identities = 82/225 (36%), Positives = 102/225 (45%), Gaps = 15/225 (6%)
Query: 251 GSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSP 310
G G C C C + GSF C C GFR C + C+ SP
Sbjct: 701 GFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSP 760
Query: 311 CRGGATCVLGPHGK---NYTCRCPQGYQLDSSQLDCVDVDECQDSPCA--QECVNTPGGF 365
C G ++ C CP G+Q +++ +C DVDEC++ QECVN+PG F
Sbjct: 761 ----PPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSF 816
Query: 366 RCE-CWVGYEPGGPGEGACQDVDECALGRSPCAQG--CTNTDGSFHCSCEEGYVLAGEDG 422
+C C G+ G C DVDEC+ G PC CTNT+GSF CSC GY
Sbjct: 817 QCRTCPSGHHLH---RGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRP 873
Query: 423 TQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
C DV+EC+ C NT GSF C C PG+ P G SC
Sbjct: 874 GPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC 918
Score = 134 bits (338), Expect = 2e-31
Identities = 81/198 (40%), Positives = 91/198 (45%), Gaps = 16/198 (8%)
Query: 277 EGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGK---NYTCRCPQG 333
E GSF C C PGFR C + C P C LG ++ C CP G
Sbjct: 604 ENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVP----PPCDLGRCENTPGSFLCVCPAG 659
Query: 334 YQLDSSQLDCVDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDVDECA 390
YQ C DVDEC SP C + C N PG FRC C G+ G +DVDECA
Sbjct: 660 YQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFR----GSACEEDVDECA 715
Query: 391 LGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGS 449
PC G C NT GSFHC+C G+ G G CQDVDEC P C NT+GS
Sbjct: 716 QEPPPCGPGRCDNTAGSFHCACPAGFRSRGP-GAPCQDVDECARSPPPCTYGRCENTEGS 774
Query: 450 FHCGCLPGWVLAPNGVSC 467
F C C G+ G C
Sbjct: 775 FQCVCPMGFQPNTAGSEC 792
Score = 124 bits (311), Expect = 3e-28
Identities = 91/245 (37%), Positives = 112/245 (45%), Gaps = 28/245 (11%)
Query: 277 EGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGKNYTCRCPQGY 334
E GSFLC C G++ +C + C+ SP C GA C P ++ C CP G+
Sbjct: 646 ENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGA-CKNLPG--SFRCVCPAGF 702
Query: 335 QLDSSQLDCVDVDEC--QDSPCAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDVDECAL 391
+ + + DVDEC + PC C NT G F C C G+ GPG CQDVDECA
Sbjct: 703 RGSACE---EDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPG-APCQDVDECAR 758
Query: 392 GRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVG----PGGPLCDSLCFNT 446
PC G C NT+GSF C C G+ G++C+DVDEC PG C N+
Sbjct: 759 SPPPCTYGRCENTEGSFQCVCPMGFQ-PNTAGSECEDVDECENHLACPGQE-----CVNS 812
Query: 447 QGSFHCGCLPGWVLAPNGVSCTMGPVSLG-PPSGPPDEEDKGEKEGSTVPRAATASPTRG 505
GSF C P G + S G PP GP EGS R + A R
Sbjct: 813 PGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGP--HGHCTNTEGSF--RCSCAPGYRA 868
Query: 506 PEGTP 510
P G P
Sbjct: 869 PSGRP 873
Score = 122 bits (307), Expect = 8e-28
Identities = 77/185 (41%), Positives = 86/185 (46%), Gaps = 19/185 (10%)
Query: 303 RNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQ--DSPCAQ-ECV 359
RNP P R C+ P G YTC C G++L C+DVDEC+ PCA C
Sbjct: 551 RNPQVCGPGR----CISRPSG--YTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCE 604
Query: 360 NTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLA 418
N+PG FRC C G+ GP C DVDEC PC G C NT GSF C C GY A
Sbjct: 605 NSPGSFRCVCGPGFR-AGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGY-QA 662
Query: 419 GEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGW---VLAPNGVSCTMGPVSLG 475
G CQDVDEC G C N GSF C C G+ + C P
Sbjct: 663 APHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEP---- 718
Query: 476 PPSGP 480
PP GP
Sbjct: 719 PPCGP 723
Score = 122 bits (307), Expect = 8e-28
Identities = 101/283 (35%), Positives = 117/283 (41%), Gaps = 34/283 (12%)
Query: 271 CHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSS--PCRGGATCVLGPHGKNYTC 328
C DGSF C C PG R DL +C + C G C P
Sbjct: 930 CQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVR 989
Query: 329 RCPQGYQLDSSQLDCVDVDECQD---SPC-AQECVNTPGGFRCE--CWVGYEPGGPGEGA 382
C GY + C DVDECQ+ C AQ C NTPG +RC C GY+P PG G
Sbjct: 990 DCDPGYHA-GPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPT-PG-GG 1046
Query: 383 CQDVDECALGRSPCAQG--CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCD 440
CQDVDEC RS C C N GSF C C++GY A DG C DV+EC G
Sbjct: 1047 CQDVDECR-NRSFCGAHAVCQNLPGSFQCLCDQGYEGA-RDGRHCVDVNECETLQGVCGA 1104
Query: 441 SLCFNTQGSFHCGCLPGWVLAPNGVSCTMGPVSLGPPSG--PPDEEDKGEKEGSTVPRAA 498
+LC N +GSF C C PN P P +G P G GS A
Sbjct: 1105 ALCENVEGSFLCVC-------PN------SPEEFDPMTGRCVPPRTSAGTFPGS--QPQA 1149
Query: 499 TASPTRGPEGTPKATPTTSRPSLSSDAPITSAPLKMLAPSGSP 541
ASP P P RPS P+ S + + +P
Sbjct: 1150 PASPVL--PARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAP 1190
Score = 122 bits (306), Expect = 1e-27
Identities = 87/246 (35%), Positives = 113/246 (45%), Gaps = 39/246 (15%)
Query: 235 SHYFLCKEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLL 294
S + L + + DV + S P C G H C +GSF C C PG+R
Sbjct: 823 SGHHLHRGRCTDVDECSSGAPPC------------GPHGHC-TNTEGSFRCSCAPGYR-- 867
Query: 295 DDLVTCASRNPCSS-SPCRGGATCVLGPHGK------NYTCRCPQGYQLDSSQLDCVDVD 347
PC+ + C G C PHG+ ++ C C GY+ C+DVD
Sbjct: 868 ---APSGRPGPCADVNECLEGDFCF--PHGECLNTDGSFACTCAPGYRPGPRGASCLDVD 922
Query: 348 ECQDSPCAQE--CVNTPGGFRCECWVGYEPGGPGEGACQDVDEC-ALGRSPC-AQGCTNT 403
EC + Q C NT G F C C G+ GP +C DVDEC G + C +Q C N+
Sbjct: 923 ECSEEDLCQSGICTNTDGSFECICPPGHR-AGPDLASCLDVDECRERGPALCGSQRCENS 981
Query: 404 DGSFHC--SCEEGYVLAGEDGTQCQDVDECVGPGGPLCDS-LCFNTQGSFHC--GCLPGW 458
GS+ C C+ GY AG +GT C DVDEC G +C + C NT GS+ C C PG+
Sbjct: 982 PGSYRCVRDCDPGY-HAGPEGT-CDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGY 1039
Query: 459 VLAPNG 464
P G
Sbjct: 1040 QPTPGG 1045
Score = 90.1 bits (222), Expect = 6e-18
Identities = 52/123 (42%), Positives = 62/123 (50%), Gaps = 6/123 (4%)
Query: 349 CQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQG-CTNTD 404
CQ +P C C++ P G+ C C G+ G C DVDEC PCA G C N+
Sbjct: 549 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGT-RCIDVDECRRVPPPCAPGRCENSP 607
Query: 405 GSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNG 464
GSF C C G+ AG +C DVDEC P C NT GSF C C G+ AP+G
Sbjct: 608 GSFRCVCGPGF-RAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHG 666
Query: 465 VSC 467
SC
Sbjct: 667 ASC 669
Score = 65.1 bits (157), Expect = 2e-10
Identities = 60/173 (34%), Positives = 73/173 (42%), Gaps = 27/173 (15%)
Query: 320 GPHGKNYTCRCP--QGYQLDSSQLDCV-DVDECQ---DSPCAQE-CVNTPGGFRCECWVG 372
G Y CP +GY S L DVDECQ D C CVNT G+ C C G
Sbjct: 1225 GTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNG 1284
Query: 373 YEPGGPGEGACQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGED----GTQCQD 427
Y C D DECA C G C NT GS+HC+CE VL G + Q
Sbjct: 1285 YYYHTQ-RLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQS 1343
Query: 428 VDECVG-----PGGPL-CDSLCFNTQGSF-HCGCLPG--WVLAPNGVSCTMGP 471
+D+ +G G L C + Q ++ C CL G W G+ C + P
Sbjct: 1344 LDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAW-----GMDCALCP 1391
Score = 62.0 bits (149), Expect = 2e-09
Identities = 30/71 (42%), Positives = 41/71 (57%), Gaps = 9/71 (12%)
Query: 311 CRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQ------ECVNTPGG 364
C G CV P G +TCRC GY+LD +++ CVD++EC ++ A C+NT G
Sbjct: 1543 CTNGR-CVRVPEG--FTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGS 1599
Query: 365 FRCECWVGYEP 375
FRC C G+ P
Sbjct: 1600 FRCICRPGFAP 1610
Score = 57.4 bits (137), Expect = 4e-08
Identities = 69/249 (27%), Positives = 88/249 (35%), Gaps = 39/249 (15%)
Query: 345 DVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQG-CTNT 403
D C + E V+ P G C G+E G+C+DVDECA G C G C NT
Sbjct: 323 DCQLCSERLGNSERVSAPDG---PCPTGFERVN---GSCEDVDECATG-GRCQHGECANT 375
Query: 404 DGSFHCSCEEGYVLAGEDGTQCQD--VDECVGPGGPLCDSLCFNTQGSFHCG-------- 453
G + C C +G++L + + E GP CF C
Sbjct: 376 RGGYTCVCPDGFLLDSSRSSCISQHVISEAKGP--------CFRVLRDGGCSLPILRNIT 427
Query: 454 ---CLPGWVLAPNGVSCTMGPV--SLG----PPSGPPDEEDKGEKEGSTVPRAATASPTR 504
C V G C + P S G P+GP + +T P P R
Sbjct: 428 KQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLG--QEPPR 485
Query: 505 GPEGTPKATPTTSRPSLSSDAPITSAPLKMLAPSGSPGVWREPSIHHATAASGPQEPAGG 564
P+ P TSRPS P P PG E + A +GP+ P G
Sbjct: 486 VSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPG--PELPLPSIPAWTGPEIPESG 543
Query: 565 DSSVATQNN 573
SS Q N
Sbjct: 544 PSSGMCQRN 552
Score = 56.6 bits (135), Expect = 7e-08
Identities = 45/125 (36%), Positives = 52/125 (41%), Gaps = 9/125 (7%)
Query: 343 CVDVDECQDSPCA-QECVNTPGG---FRCECWVGYEPGGPGEGACQDVDECALGRSP-CA 397
C V E S C Q+C T C GY +DVDEC L R C
Sbjct: 1207 CCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCK 1266
Query: 398 QG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDS-LCFNTQGSFHCGCL 455
G C NT + C C GY + +C D DEC P C+ C NT GS+HC C
Sbjct: 1267 SGVCVNTAPGYSCYCSNGYYYHTQR-LECIDNDECADEE-PACEGGRCVNTVGSYHCTCE 1324
Query: 456 PGWVL 460
P VL
Sbjct: 1325 PPLVL 1329
Score = 53.9 bits (128), Expect = 5e-07
Identities = 35/99 (35%), Positives = 47/99 (47%), Gaps = 10/99 (10%)
Query: 321 PHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGE 380
P G +Y + Y+ ++ +C +D C + CV P GF C C+ GY
Sbjct: 1516 PEGGSYAGSLAEPYEELEAE-ECGILDGCTNG----RCVRVPEGFTCRCFDGYRLDMT-R 1569
Query: 381 GACQDVDEC--ALGRSP-CAQG-CTNTDGSFHCSCEEGY 415
AC D++EC A SP C C NTDGSF C C G+
Sbjct: 1570 MACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGF 1608
Score = 51.2 bits (121), Expect = 3e-06
Identities = 24/62 (38%), Positives = 31/62 (50%), Gaps = 6/62 (9%)
Query: 311 CRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQE---CVNTPGGFRC 367
C+ G P Y+C C GY + +L+C+D DEC D A E CVNT G + C
Sbjct: 1265 CKSGVCVNTAP---GYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHC 1321
Query: 368 EC 369
C
Sbjct: 1322 TC 1323
Score = 49.3 bits (116), Expect = 1e-05
Identities = 31/81 (38%), Positives = 39/81 (48%), Gaps = 14/81 (17%)
Query: 383 CQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQ--CQDVDEC--VGPGGPL 438
C +D C GR C F C C +GY L D T+ C D++EC PL
Sbjct: 1537 CGILDGCTNGR------CVRVPEGFTCRCFDGYRL---DMTRMACVDINECDEAEAASPL 1587
Query: 439 C-DSLCFNTQGSFHCGCLPGW 458
C ++ C NT GSF C C PG+
Sbjct: 1588 CVNARCLNTDGSFRCICRPGF 1608
Score = 39.3 bits (90), Expect = 0.012
Identities = 28/91 (30%), Positives = 41/91 (45%), Gaps = 10/91 (10%)
Query: 379 GEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQ--CQDVDECVGPGG 436
G G V +C L C++ N++ S +G G + C+DVDEC GG
Sbjct: 314 GAGLAWGVHDCQL----CSERLGNSE---RVSAPDGPCPTGFERVNGSCEDVDECA-TGG 365
Query: 437 PLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
C NT+G + C C G++L + SC
Sbjct: 366 RCQHGECANTRGGYTCVCPDGFLLDSSRSSC 396
>gi|19743803 fibulin 5 precursor [Homo sapiens]
Length = 448
Score = 134 bits (337), Expect = 3e-31
Identities = 74/183 (40%), Positives = 96/183 (52%), Gaps = 11/183 (6%)
Query: 287 CRPGFRLLDDLVTCASRNPCS--SSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCV 344
CR G+++ D+ C + C+ S C C+ G YTC C GY L Q C+
Sbjct: 113 CRFGYQM-DESNQCVDVDECATDSHQCNPTQICINTEGG--YTCSCTDGYWLLEGQ--CL 167
Query: 345 DVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTD 404
D+DEC+ C Q C N PG + C C G+ G +CQDV+ECA +PC Q C NT
Sbjct: 168 DIDECRYGYCQQLCANVPGSYSCTCNPGFTLNEDGR-SCQDVNECAT-ENPCVQTCVNTY 225
Query: 405 GSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNG 464
GSF C C+ GY L EDG C D+DEC LC C N G++ C C PG++L +
Sbjct: 226 GSFICRCDPGYELE-EDGVHCSDMDEC-SFSEFLCQHECVNQPGTYFCSCPPGYILLDDN 283
Query: 465 VSC 467
SC
Sbjct: 284 RSC 286
Score = 119 bits (297), Expect = 1e-26
Identities = 67/144 (46%), Positives = 79/144 (54%), Gaps = 15/144 (10%)
Query: 330 CPQGYQLDSSQLDCVDVDEC-----QDSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQ 384
C GYQ+D S CVDVDEC Q +P Q C+NT GG+ C C GY EG C
Sbjct: 113 CRFGYQMDESN-QCVDVDECATDSHQCNP-TQICINTEGGYTCSCTDGY---WLLEGQCL 167
Query: 385 DVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCF 444
D+DEC G C Q C N GS+ C+C G+ L EDG CQDV+EC C C
Sbjct: 168 DIDECRYGY--CQQLCANVPGSYSCTCNPGFTL-NEDGRSCQDVNECATENP--CVQTCV 222
Query: 445 NTQGSFHCGCLPGWVLAPNGVSCT 468
NT GSF C C PG+ L +GV C+
Sbjct: 223 NTYGSFICRCDPGYELEEDGVHCS 246
Score = 118 bits (295), Expect = 2e-26
Identities = 68/198 (34%), Positives = 92/198 (46%), Gaps = 16/198 (8%)
Query: 257 CVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGAT 316
C + + CN Q C +G + C C G+ LL+ C + C C+
Sbjct: 131 CATDSHQCNPT-----QICINT-EGGYTCSCTDGYWLLEG--QCLDIDECRYGYCQQLCA 182
Query: 317 CVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQ-DSPCAQECVNTPGGFRCECWVGYEP 375
V G +Y+C C G+ L+ C DV+EC ++PC Q CVNT G F C C GYE
Sbjct: 183 NVPG----SYSCTCNPGFTLNEDGRSCQDVNECATENPCVQTCVNTYGSFICRCDPGYEL 238
Query: 376 GGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPG 435
G C D+DEC+ C C N G++ CSC GY+L +D CQD++EC
Sbjct: 239 EEDGVH-CSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILL-DDNRSCQDINECEHRN 296
Query: 436 GPL-CDSLCFNTQGSFHC 452
C+N QG F C
Sbjct: 297 HTCNLQQTCYNLQGGFKC 314
Score = 89.4 bits (220), Expect = 1e-17
Identities = 62/197 (31%), Positives = 78/197 (39%), Gaps = 59/197 (29%)
Query: 321 PHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCA----QECVNTPGGFRC--------- 367
P N +C G+ LD C+D+DEC+ P A CVN GG+ C
Sbjct: 18 PSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNPVYR 77
Query: 368 ----------------------------------ECWVGYEPGGPGEGACQDVDECALGR 393
C GY+ + C DVDECA
Sbjct: 78 GPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQ--CVDVDECATDS 135
Query: 394 SPC--AQGCTNTDGSFHCSCEEGY-VLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSF 450
C Q C NT+G + CSC +GY +L G QC D+DEC C LC N GS+
Sbjct: 136 HQCNPTQICINTEGGYTCSCTDGYWLLEG----QCLDIDEC---RYGYCQQLCANVPGSY 188
Query: 451 HCGCLPGWVLAPNGVSC 467
C C PG+ L +G SC
Sbjct: 189 SCTCNPGFTLNEDGRSC 205
Score = 45.1 bits (105), Expect = 2e-04
Identities = 36/151 (23%), Positives = 53/151 (35%), Gaps = 52/151 (34%)
Query: 358 CVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCA--QGCTNTDGSFHC------ 409
C+ +PG + +C G++ G C D+DEC C C N +G + C
Sbjct: 16 CLPSPGNAQAQCTNGFDLDRQS-GQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNP 74
Query: 410 -------------------------------------SCEEGYVLAGEDGTQCQDVDECV 432
C GY + ++ QC DVDEC
Sbjct: 75 VYRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQM--DESNQCVDVDEC- 131
Query: 433 GPGGPLCD--SLCFNTQGSFHCGCLPG-WVL 460
C+ +C NT+G + C C G W+L
Sbjct: 132 ATDSHQCNPTQICINTEGGYTCSCTDGYWLL 162
Score = 39.3 bits (90), Expect = 0.012
Identities = 36/121 (29%), Positives = 44/121 (36%), Gaps = 27/121 (22%)
Query: 400 CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDEC-VGPGGPLCDSLCFNTQGSFHCGCLPGW 458
C + G+ C G+ L + G QC D+DEC P D +C N G + C+P
Sbjct: 16 CLPSPGNAQAQCTNGFDLDRQSG-QCLDIDECRTIPEACRGDMMCVNQNGGYL--CIP-- 70
Query: 459 VLAPNGVSCTMGPVSLGPPSGPPDEEDKGEKEGSTVPRAATASPTRGPEGTPKATPTTSR 518
PV GP S P G P A A P P PT SR
Sbjct: 71 ---------RTNPVYRGPYSNPYSTPYSG-------PYPAAAPPLSAPN-----YPTISR 109
Query: 519 P 519
P
Sbjct: 110 P 110
>gi|56237021 fibrillin 3 precursor [Homo sapiens]
Length = 2809
Score = 130 bits (327), Expect = 4e-30
Identities = 65/147 (44%), Positives = 82/147 (55%), Gaps = 5/147 (3%)
Query: 325 NYTCRCPQGYQLDSSQLDCVDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPGEG 381
++ C C G+ LD+ + +C D+DEC+ SP C Q CVNTPG F CEC+ GYE G
Sbjct: 1008 SFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMK 1067
Query: 382 ACQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCD 440
C DVDECA C G CTNTDGS+ C C G+ L + GT C+D+DEC G
Sbjct: 1068 NCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAK-GTACEDIDECSLSDGLCPH 1126
Query: 441 SLCFNTQGSFHCGCLPGWVLAPNGVSC 467
C N G+F C C G+ P+ C
Sbjct: 1127 GQCVNVIGAFQCSCHAGFQSTPDRQGC 1153
Score = 130 bits (326), Expect = 5e-30
Identities = 79/211 (37%), Positives = 103/211 (48%), Gaps = 13/211 (6%)
Query: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSP-CRGGATCVLGPH 322
C G C GSF C C GF L C + C SP G TCV P
Sbjct: 990 CKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTP- 1048
Query: 323 GKNYTCRCPQGYQLDSSQL-DCVDVDECQDSPC---AQECVNTPGGFRCECWVGYEPGGP 378
++ C C GY+ + +C+DVDEC P C NT G ++C+C G+E
Sbjct: 1049 -GSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAK 1107
Query: 379 GEGACQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDEC-VGPGG 436
G AC+D+DEC+L C G C N G+F CSC G+ + D C D++EC V GG
Sbjct: 1108 GT-ACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGF-QSTPDRQGCVDINECRVQNGG 1165
Query: 437 PLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
CD C NT+GS+ C C G+ L P+G +C
Sbjct: 1166 --CDVHCINTEGSYRCSCGQGYSLMPDGRAC 1194
Score = 127 bits (320), Expect = 2e-29
Identities = 76/211 (36%), Positives = 102/211 (48%), Gaps = 13/211 (6%)
Query: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLV-TCASRNPCSSSP--CRGGATCVLG 320
C + C Q GSF C C PG+ L+ C + C+ P CRGG TC
Sbjct: 1032 CRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGG-TCT-- 1088
Query: 321 PHGKNYTCRCPQGYQLDSSQLDCVDVDECQ--DSPCAQ-ECVNTPGGFRCECWVGYEPGG 377
+Y C+CP G++L + C D+DEC D C +CVN G F+C C G++
Sbjct: 1089 NTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQ-ST 1147
Query: 378 PGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGP 437
P C D++EC + C C NT+GS+ CSC +GY L DG C DVDEC
Sbjct: 1148 PDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLM-PDGRACADVDEC-EENPR 1205
Query: 438 LCD-SLCFNTQGSFHCGCLPGWVLAPNGVSC 467
+CD C N G C C G++ P+ +C
Sbjct: 1206 VCDQGHCTNMPGGHRCLCYDGFMATPDMRTC 1236
Score = 127 bits (320), Expect = 2e-29
Identities = 95/293 (32%), Positives = 118/293 (40%), Gaps = 53/293 (18%)
Query: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQ 340
GSFLC C G+ L +D TC + C+S CV +TCRCP G+
Sbjct: 2425 GSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGA--FTCRCPPGFTQHHQA 2482
Query: 341 LDCVDVDEC--QDSPCAQE--CVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPC 396
C D DEC Q PC C NTPG FRCEC G+ G G C+DV+EC G C
Sbjct: 2483 --CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHG-CEDVNECD-GPHRC 2538
Query: 397 AQGCTNTDGSFHCSCEEGYVL-------------------------------------AG 419
GC N G + CSC +G+ +G
Sbjct: 2539 QHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSG 2598
Query: 420 EDGTQ----CQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSCTMGPVSLG 475
D Q CQ+VDEC G GP C C NT G F CGC G+ A G C G
Sbjct: 2599 FDFDQALGGCQEVDECAGRRGP-CSYSCANTPGGFLCGCPQGYFRAGQG-HCVSGLGFSP 2656
Query: 476 PPSGPPDEEDKGEKEGSTVPRAATASPTRGPEGTPKATPTTSRPSLSSDAPIT 528
P PD+E+ E + SP P + + +L S+A +T
Sbjct: 2657 GPQDTPDKEELLSSEACYECKINGLSPRDRPRRSAHRDHQVNLATLDSEALLT 2709
Score = 127 bits (318), Expect = 4e-29
Identities = 87/250 (34%), Positives = 116/250 (46%), Gaps = 21/250 (8%)
Query: 225 CGEGDKDETQSHYFLCKEKAPDVFDWGSSGPLCVSPKYGCNFNNGGC--HQDCFEGGDGS 282
C GD + T+ F+C + + G++G V C C H C GS
Sbjct: 1249 CLHGDCENTKGS-FVCHCQLGYMVRKGATGCSDVDE---CEVGGHNCDSHASCLNI-PGS 1303
Query: 283 FLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGKNYTCRCPQGYQLDSSQ 340
F C C PG+ + D C + C S C C+ P +Y C C QG+ D
Sbjct: 1304 FSCRCLPGW--VGDGFECHDLDECVSQEHRCSPRGDCLNVPG--SYRCTCRQGFAGDG-- 1357
Query: 341 LDCVDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCA 397
C D DEC ++ C +C+N PGG+RCEC +G++P ACQDVDECA G
Sbjct: 1358 FFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPT-EDHRACQDVDECAQGNLCAF 1416
Query: 398 QGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPG 457
C N G F C C GY L G C D++EC P + + +C NT GS+ C C
Sbjct: 1417 GSCENLPGMFRCICNGGYEL-DRGGGNCTDINECADPVNCI-NGVCINTPGSYLCSCPQD 1474
Query: 458 WVLAPNGVSC 467
+ L P+GV C
Sbjct: 1475 FELNPSGVGC 1484
Score = 126 bits (317), Expect = 5e-29
Identities = 79/191 (41%), Positives = 100/191 (52%), Gaps = 14/191 (7%)
Query: 282 SFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQL 341
S+ C C G+ D C + C+SSPC G CV P Y CRC G+Q ++
Sbjct: 430 SYRCECNVGYTQ-DVRGECIDVDECTSSPCHHG-DCVNIPG--TYHCRCYPGFQATPTRQ 485
Query: 342 DCVDVDEC--QDSPC-AQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQ 398
CVDVDEC C CVNT G F+C C G+E G+ C D +ECA + C
Sbjct: 486 ACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKN-CVDHNECATS-TMCVN 543
Query: 399 G-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLC-DSLCFNTQGSFHCGCLP 456
G C N DGSF C C+ G++LA G C D+DEC PG +C + C NT+GSF C CL
Sbjct: 544 GVCLNEDGSFSCLCKPGFLLA-PGGHYCMDIDECQTPG--ICVNGHCTNTEGSFRCQCLG 600
Query: 457 GWVLAPNGVSC 467
G + +G C
Sbjct: 601 GLAVGTDGRVC 611
Score = 126 bits (316), Expect = 7e-29
Identities = 81/214 (37%), Positives = 99/214 (46%), Gaps = 22/214 (10%)
Query: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGP 321
C NGGC C +GS+ C C G+ L+ D CA + C +P C G C P
Sbjct: 1159 CRVQNGGCDVHCINT-EGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGH-CTNMP 1216
Query: 322 HGKNYTCRCPQGYQLDSSQLDCVDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGP 378
G + C C G+ CVDVDEC +P C +C NT G F C C +GY
Sbjct: 1217 GG--HRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMV-RK 1273
Query: 379 GEGACQDVDECALGRSPCAQ--GCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPG- 435
G C DVDEC +G C C N GSF C C G+V DG +C D+DECV
Sbjct: 1274 GATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWV---GDGFECHDLDECVSQEH 1330
Query: 436 --GPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
P D C N GS+ C C G+ A +G C
Sbjct: 1331 RCSPRGD--CLNVPGSYRCTCRQGF--AGDGFFC 1360
Score = 125 bits (315), Expect = 9e-29
Identities = 75/173 (43%), Positives = 93/173 (53%), Gaps = 15/173 (8%)
Query: 304 NPCSSSP--CRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQ-DSPCAQ-ECV 359
N C+ +P C G CV ++ C CP GY LD + ++CVD DEC PC Q C
Sbjct: 2086 NECAENPGVCTNGV-CV--NTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGTCT 2142
Query: 360 NTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAG 419
N GGF C C G+EPG C+D+DEC+L CA C NT+GS+ C+C GY L
Sbjct: 2143 NVIGGFECACADGFEPGLMM--TCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLR- 2199
Query: 420 EDGTQCQDVDECVGPGGPLCDSL---CFNTQGSFHCGCLPGWVLAP-NGVSCT 468
EDG C+DVDEC G C + C N G+F C C PG P +G CT
Sbjct: 2200 EDGAMCRDVDEC-ADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCT 2251
Score = 124 bits (310), Expect = 4e-28
Identities = 78/223 (34%), Positives = 102/223 (45%), Gaps = 18/223 (8%)
Query: 252 SSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPC 311
S G CV N H DC + +GS++C C GF+ D C + C PC
Sbjct: 1798 SPGGACVGRNECREIPNVCSHGDCMDT-EGSYMCLCHRGFQASADQTLCMDIDECDRQPC 1856
Query: 312 RGGATC--VLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQD---SPCA-QECVNTPGGF 365
G TC ++G +Y C C G+ + + DCVD DEC C C+NT G F
Sbjct: 1857 -GNGTCKNIIG----SYNCLCFPGFVVTHNG-DCVDFDECTTLVGQVCRFGHCLNTAGSF 1910
Query: 366 RCECWVGYEPGGPGEGACQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQ 424
C C G+E G+ C D +EC C G C N +GSF C C G+ + +
Sbjct: 1911 HCLCQDGFELTADGKN-CVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSD---H 1966
Query: 425 CQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
C D+DEC C N+ GSF C C PG+VL+ NG C
Sbjct: 1967 CIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRC 2009
Score = 117 bits (294), Expect = 3e-26
Identities = 79/215 (36%), Positives = 106/215 (49%), Gaps = 22/215 (10%)
Query: 264 CNFNNGGC-HQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCS--SSPCRGGATCVLG 320
C+ N C H DC E GSF+C C+ G+ + C+ + C C A+C+
Sbjct: 1242 CDLNPHICLHGDC-ENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNI 1300
Query: 321 PHGKNYTCRCPQGYQLDSSQLDCVDVDEC--QDSPCAQ--ECVNTPGGFRCECWVGYEPG 376
P +++CRC G+ D +C D+DEC Q+ C+ +C+N PG +RC C G+
Sbjct: 1301 PG--SFSCRCLPGWVGDG--FECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFA-- 1354
Query: 377 GPGEGA-CQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGP 434
G+G C+D DECA C G C N G + C CE G+ ED CQDVDEC
Sbjct: 1355 --GDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPT-EDHRACQDVDECAQ- 1410
Query: 435 GGPLCD-SLCFNTQGSFHCGCLPGWVLAPNGVSCT 468
G LC C N G F C C G+ L G +CT
Sbjct: 1411 -GNLCAFGSCENLPGMFRCICNGGYELDRGGGNCT 1444
Score = 115 bits (288), Expect = 1e-25
Identities = 74/193 (38%), Positives = 102/193 (52%), Gaps = 16/193 (8%)
Query: 280 DGSFLCGCR-PGFRLLDDLVTCASRN--PCSSSPCRGGATCVLGPHGKNYTCRCPQGYQL 336
D LCG + PGF L D+ T + C P + G ++ C CP G+
Sbjct: 1698 DYQILCGNQAPGF--LTDIHTGKPLDIDECGEIPAICANGICINQIG-SFRCECPAGFNY 1754
Query: 337 DSSQLDCVDVDEC--QDSPCAQ--ECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALG 392
+S L C DVDEC ++SPC Q +C+N PG +RC+C GY+ PG GAC +EC
Sbjct: 1755 NSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKL-SPG-GACVGRNECREI 1812
Query: 393 RSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFH 451
+ C+ G C +T+GS+ C C G+ A D T C D+DEC P + C N GS++
Sbjct: 1813 PNVCSHGDCMDTEGSYMCLCHRGF-QASADQTLCMDIDEC--DRQPCGNGTCKNIIGSYN 1869
Query: 452 CGCLPGWVLAPNG 464
C C PG+V+ NG
Sbjct: 1870 CLCFPGFVVTHNG 1882
Score = 114 bits (286), Expect = 2e-25
Identities = 85/235 (36%), Positives = 99/235 (42%), Gaps = 46/235 (19%)
Query: 263 GCNFNNGGCHQD---CFEGG----DGSFLCGCRPGFRLLDDLVTCAS--RNPC------- 306
GC +N CH C G GSF C C GF+ L C + PC
Sbjct: 2249 GCTDDNE-CHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQT 2307
Query: 307 ------SSSPCRGGATCVLG--------------PHGKNYTCRCPQGYQLDSSQLDCVDV 346
SSS A C G P Y CP G + DV
Sbjct: 2308 MCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHG---SGYTAEGRDV 2364
Query: 347 DECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNT 403
DEC+ CA EC+N+ G FRC C GY P C D+DEC+ PC C NT
Sbjct: 2365 DECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATAT-TCLDMDECSQVPKPCTFLCKNT 2423
Query: 404 DGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGW 458
GSF CSC GY+L EDG C+D+DEC C LC NT G+F C C PG+
Sbjct: 2424 KGSFLCSCPRGYLLE-EDGRTCKDLDECTSRQHN-CQFLCVNTVGAFTCRCPPGF 2476
Score = 113 bits (283), Expect = 5e-25
Identities = 65/155 (41%), Positives = 75/155 (48%), Gaps = 10/155 (6%)
Query: 270 GCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSP-CRGGATCVLGPHGKNYTC 328
G H C GSF C C GF L+ C N C C+ G LG Y C
Sbjct: 2497 GAHGHC-HNTPGSFRCECHQGFTLVSSGHGCEDVNECDGPHRCQHGCQNQLG----GYRC 2551
Query: 329 RCPQGYQLDSSQLDCVDVDECQDSP--CAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQD 385
CPQG+ S CVD +EC SP C C NT GGFRC C G++ G CQ+
Sbjct: 2552 SCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFD-FDQALGGCQE 2610
Query: 386 VDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGE 420
VDECA R PC+ C NT G F C C +GY AG+
Sbjct: 2611 VDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQ 2645
Score = 96.7 bits (239), Expect = 6e-20
Identities = 51/111 (45%), Positives = 62/111 (55%), Gaps = 6/111 (5%)
Query: 358 CVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYV 416
C+ TP +RCEC VGY GE C DVDEC SPC G C N G++HC C G+
Sbjct: 424 CLPTPSSYRCECNVGYTQDVRGE--CIDVDECT--SSPCHHGDCVNIPGTYHCRCYPGFQ 479
Query: 417 LAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
A C DVDEC+ GG C NT+GSF C C G+ L+P+G +C
Sbjct: 480 -ATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNC 529
Score = 91.7 bits (226), Expect = 2e-18
Identities = 76/237 (32%), Positives = 97/237 (40%), Gaps = 50/237 (21%)
Query: 273 QDCFEGGD------GSFLCGCRPGFRLLDDLVT-CASRNPCSSSP--CRGGATCVLGPHG 323
QDC G G+F C C PG R L C N C + P C G CV
Sbjct: 2216 QDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGR-CV--NTA 2272
Query: 324 KNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQECVNT---------PGGFRCECWVGYE 374
++ C C +G+Q + +C D+ + PC E + T R EC G
Sbjct: 2273 GSFRCDCDEGFQPSPTLTECHDI---RQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGG 2329
Query: 375 PG-GPGEGAC----------------------QDVDECALGRSPCAQG-CTNTDGSFHCS 410
G GP C +DVDEC + CA G C N+ GSF C
Sbjct: 2330 RGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCH 2389
Query: 411 CEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
C+ GY T C D+DEC P C LC NT+GSF C C G++L +G +C
Sbjct: 2390 CQAGYT-PDATATTCLDMDECSQVPKP-CTFLCKNTKGSFLCSCPRGYLLEEDGRTC 2444
Score = 91.3 bits (225), Expect = 3e-18
Identities = 67/234 (28%), Positives = 92/234 (39%), Gaps = 32/234 (13%)
Query: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHG 323
C + G CH +GSF C C GF L D C N C++S C L G
Sbjct: 493 CIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVC-LNEDG 551
Query: 324 KNYTCRCPQGYQLDSSQLDCVDVDECQ-DSPCAQ-ECVNTPGGFRCECWVGYEPGGPGEG 381
+++C C G+ L C+D+DECQ C C NT G FRC+C G G G
Sbjct: 552 -SFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGR- 609
Query: 382 ACQDV---DEC--ALGRSPCAQGCTNTDGSFHCSC--------EEGYVLAGEDGTQCQ-- 426
C D C A+ + CA+ T C C E + +D + Q
Sbjct: 610 VCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKDSAEFQAL 669
Query: 427 ------------DVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSCT 468
D++EC + +C N +GS+ C C G+ +G CT
Sbjct: 670 CSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCT 723
Score = 88.6 bits (218), Expect = 2e-17
Identities = 66/237 (27%), Positives = 97/237 (40%), Gaps = 45/237 (18%)
Query: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGK---NYTCRCPQGYQLD 337
GSF C C+ GF L D C N C S TC+ G ++ C CP G+Q+
Sbjct: 1908 GSFHCLCQDGFELTADGKNCVDTNECLSL----AGTCLPGTCQNLEGSFRCICPPGFQVQ 1963
Query: 338 SSQLDCVDVDECQDSP---CAQECVNTPGGFRCECWVGYEPGGPGEGACQ---------- 384
S C+D+DEC + P C N+PG F+C C G+ G
Sbjct: 1964 SDH--CIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRF 2021
Query: 385 DVDECALGRS--------------------PCAQGCTNTDGSFHCSCEEGY-VLAGEDGT 423
+ +C++ ++ PC +F C G+ + G D +
Sbjct: 2022 EAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDS 2081
Query: 424 QCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSCT-MGPVSLGPPSG 479
+ +DV+EC G + +C NT GSF C C G+ L G++C S+G P G
Sbjct: 2082 R-EDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCG 2137
Score = 85.9 bits (211), Expect = 1e-16
Identities = 57/165 (34%), Positives = 74/165 (44%), Gaps = 17/165 (10%)
Query: 271 CHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLG---PHGKNYT 327
CH G++ C C PGF+ C + C S G C LG ++
Sbjct: 458 CHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVS----GGLCHLGRCVNTEGSFQ 513
Query: 328 CRCPQGYQLDSSQLDCVDVDECQDSPCAQE--CVNTPGGFRCECWVGYEPGGPGEGACQD 385
C C G++L +CVD +EC S C+N G F C C G+ PG C D
Sbjct: 514 CVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLL-APGGHYCMD 572
Query: 386 VDECALGRSP--CAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQD 427
+DEC ++P C G CTNT+GSF C C G + G DG C D
Sbjct: 573 IDEC---QTPGICVNGHCTNTEGSFRCQCLGG-LAVGTDGRVCVD 613
Score = 85.9 bits (211), Expect = 1e-16
Identities = 68/208 (32%), Positives = 84/208 (40%), Gaps = 35/208 (16%)
Query: 248 FDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCS 307
++ G+SG C C N+ C + GS+ C C PGF D C + C
Sbjct: 713 YEAGASGKDCTDVDE-CALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECL 771
Query: 308 SSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVD------ECQDSPCAQECVNT 361
SSPC G L +YTC+C G +LD S C+D + Q+S C VN
Sbjct: 772 SSPCVSGVCRNL---AGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCE---VNL 825
Query: 362 PG-GFRCEC--WVGYEPGGPGEG-----------------ACQDVDECALGRSPCAQG-C 400
G R EC +G G P E C DV+EC C G C
Sbjct: 826 QGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPGVCPNGRC 885
Query: 401 TNTDGSFHCSCEEGYVLAGEDGTQCQDV 428
NT GSF C C EG +L G C DV
Sbjct: 886 VNTAGSFRCECPEGLML-DASGRLCVDV 912
Score = 82.4 bits (202), Expect = 1e-15
Identities = 102/367 (27%), Positives = 134/367 (36%), Gaps = 59/367 (16%)
Query: 165 CGSPG----SPGSNIEGFVCKFSFKGMCRP-LALGGPGQVTYTTPFQTTSSSLEAVPFAS 219
C +PG +N EG SF+ C LA+G G+V T ++T A+ S
Sbjct: 576 CQTPGICVNGHCTNTEG-----SFRCQCLGGLAVGTDGRVCVDTHVRSTCYG--AIEKGS 628
Query: 220 AANVACGEGDKDE----TQSHYF-----LCKEKAPDVFDWGSSGPLCVSPK----YGCNF 266
A G K E H F LC K F S L ++ C
Sbjct: 629 CARPFPGTVTKSECCCANPDHGFGEPCQLCPAKDSAEFQALCSSGLGITTDGRDINECAL 688
Query: 267 NNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCS--SSPCRGGATCVLGPHGK 324
+ C E GS+ C C G+ C + C+ S C G C P
Sbjct: 689 DPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNG-WCQNSPG-- 745
Query: 325 NYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQE-CVNTPGGFRCECWVG--YEPGGP--- 378
+Y+C CP G+ C DVDEC SPC C N G + C+C G +P G
Sbjct: 746 SYSCSCPPGFHFWQDTEICKDVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCL 805
Query: 379 -----------GEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYV-------LAGE 420
E C+ + A RS C C ++ CE + A
Sbjct: 806 DSTKGTCWLKIQESRCEVNLQGASLRSEC---CATLGAAWGSPCERCEIDPACARGFARM 862
Query: 421 DGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSCTMGPVSLGPPSGP 480
G C DV+EC G + C NT GSF C C G +L +G C V L P
Sbjct: 863 TGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCV--DVRLEPCFLR 920
Query: 481 PDEEDKG 487
DE++ G
Sbjct: 921 WDEDECG 927
Score = 82.0 bits (201), Expect = 2e-15
Identities = 65/225 (28%), Positives = 86/225 (38%), Gaps = 41/225 (18%)
Query: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQ 340
G F C C G+ L C N C+ C+ P +Y C CPQ ++L+ S
Sbjct: 1424 GMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPG--SYLCSCPQDFELNPSG 1481
Query: 341 LDCVDVD------ECQDS-----PCAQECVNTPGGFRCECWVGYEPGGP----------- 378
+ CVD E D C+ E C C +G G P
Sbjct: 1482 VGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTE 1541
Query: 379 -------GEG--------ACQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDG 422
GEG +D+DEC C G C NT GSF C C GY L+ E
Sbjct: 1542 YRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLS-EHT 1600
Query: 423 TQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
C+D+DEC G C+NT G++ C C ++ G +C
Sbjct: 1601 RICEDIDECSTHSGICGPGTCYNTLGNYTCVCPAEYLQVNGGNNC 1645
Score = 80.1 bits (196), Expect = 6e-15
Identities = 73/237 (30%), Positives = 94/237 (39%), Gaps = 59/237 (24%)
Query: 277 EGGD-----GSFLCGCRPGFRLLDDLVTCASRNPCSS-SPCRGGATC--VLGPHGKNYTC 328
+GGD GSF C C PG+ L + C + CS+ S G TC LG NYTC
Sbjct: 1575 QGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSGICGPGTCYNTLG----NYTC 1630
Query: 329 RCPQGYQLDSSQLDCVDVDE----------CQDS---------PCAQECVNTPGGFRCE- 368
CP Y + +C+D+ + CQ+ C + CE
Sbjct: 1631 VCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFNVTRKMCCCSYNIGQAWNRPCEA 1690
Query: 369 CWVGYEPG--------GPG------EGACQDVDECALGRSPCAQG-CTNTDGSFHCSCEE 413
C P PG G D+DEC + CA G C N GSF C C
Sbjct: 1691 CPTPISPDYQILCGNQAPGFLTDIHTGKPLDIDECGEIPAICANGICINQIGSFRCECPA 1750
Query: 414 GY-----VLAGEDGTQCQDVDECVGPGGPLCDSL-CFNTQGSFHCGCLPGWVLAPNG 464
G+ +LA C+DVDEC P + C N GS+ C C G+ L+P G
Sbjct: 1751 GFNYNSILLA------CEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGG 1801
Score = 77.0 bits (188), Expect = 5e-14
Identities = 47/132 (35%), Positives = 58/132 (43%), Gaps = 15/132 (11%)
Query: 258 VSPKYGCNFNNG-----GCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCS-SSPC 311
VS +GC N C C + G + C C GF C N C+ S P
Sbjct: 2520 VSSGHGCEDVNECDGPHRCQHGC-QNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPT 2578
Query: 312 RGGATC--VLGPHGKNYTCRCPQGYQLDSSQLDCVDVDEC--QDSPCAQECVNTPGGFRC 367
G A+C LG + C CP G+ D + C +VDEC + PC+ C NTPGGF C
Sbjct: 2579 CGSASCRNTLG----GFRCVCPSGFDFDQALGGCQEVDECAGRRGPCSYSCANTPGGFLC 2634
Query: 368 ECWVGYEPGGPG 379
C GY G G
Sbjct: 2635 GCPQGYFRAGQG 2646
Score = 58.5 bits (140), Expect = 2e-08
Identities = 74/285 (25%), Positives = 92/285 (32%), Gaps = 70/285 (24%)
Query: 169 GSPGSNIEGFVCKFSFKGMCRPLALGGPGQVTYTTPFQTTSSSLEAVPFASAANVACGEG 228
GSPG VC F C P PG+ P ACGEG
Sbjct: 49 GSPGILQGPNVCGSRFHAYCCPGWRTFPGRSQCVVPI---------------CRRACGEG 93
Query: 229 DKDETQSHYFLCKEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGD-GSFLCGC 287
+Q + C + G+ P C + GC C GG C C
Sbjct: 94 FC--SQPNLCTCAD--------GTLAPSCGVSR------GSGCSVSCMNGGTCRGASCLC 137
Query: 288 RPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDC---- 343
+ G+ P C G C+ GP+ C C G+ + D
Sbjct: 138 QKGY------TGTVCGQPICDRGCHNGGRCI-GPN----RCACVYGFMGPQCERDYRTGP 186
Query: 344 ----VDVDECQDSPCAQEC--------VNTPGGFRCE--------CWVGYEPGGPGEGAC 383
V + CQ C V G CE C G+ P GAC
Sbjct: 187 CFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPHPCRRGFIPN-IHTGAC 245
Query: 384 QDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQD 427
QDVDEC C G C N GSFHC C G+ L+ + C+D
Sbjct: 246 QDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLS-DSSAACED 289
Score = 50.4 bits (119), Expect = 5e-06
Identities = 58/219 (26%), Positives = 73/219 (33%), Gaps = 59/219 (26%)
Query: 287 CRPGFRLLDDLVTCA----------SRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQL 336
C GF +L TCA SR S C G TC + +C C +GY
Sbjct: 90 CGEGFCSQPNLCTCADGTLAPSCGVSRGSGCSVSCMNGGTC------RGASCLCQKGYT- 142
Query: 337 DSSQLDCVDVDECQDSPCAQECVNTP---GGFRCECWVG---------YEPG------GP 378
C C + C N G RC C G Y G GP
Sbjct: 143 ---------GTVCGQPICDRGCHNGGRCIGPNRCACVYGFMGPQCERDYRTGPCFGQVGP 193
Query: 379 GEGACQDVDECALGRSPCAQGCTNTDGSFHCSCE----------EGYVLAGEDGTQCQDV 428
EG + ++ C C ++ CE G++ G CQDV
Sbjct: 194 -EGCQHQLTGLVCTKALC---CATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGA-CQDV 248
Query: 429 DECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
DEC G C N GSFHC C G L+ + +C
Sbjct: 249 DECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAAC 287
>gi|190343004 EGF-containing fibulin-like extracellular matrix
protein 2 [Homo sapiens]
Length = 443
Score = 130 bits (326), Expect = 5e-30
Identities = 71/176 (40%), Positives = 93/176 (52%), Gaps = 11/176 (6%)
Query: 287 CRPGFRLLDDLVTCASRNPCSSS--PCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCV 344
C PG+ DD +C + C+ + CR C P +Y C CP GY+ + CV
Sbjct: 109 CPPGYEP-DDQDSCVDVDECAQALHDCRPSQDCHNLPG--SYQCTCPDGYRKIGPE--CV 163
Query: 345 DVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTD 404
D+DEC+ C CVN PG FRC+C G++ GP +C DV+EC +G +PC Q C N+
Sbjct: 164 DIDECRYRYCQHRCVNLPGSFRCQCEPGFQL-GPNNRSCVDVNECDMG-APCEQRCFNSY 221
Query: 405 GSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVL 460
G+F C C +GY L DG C D+DEC LC C N G F C C G+ L
Sbjct: 222 GTFLCRCHQGYEL-HRDGFSCSDIDEC-SYSSYLCQYRCVNEPGRFSCHCPQGYQL 275
Score = 113 bits (283), Expect = 5e-25
Identities = 75/215 (34%), Positives = 94/215 (43%), Gaps = 44/215 (20%)
Query: 287 CRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGKNYTCR--------------- 329
C G+ D C N C + P C+G C+ H Y C
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCI--NHYGGYLCLPRSAAVINDLHGEGP 96
Query: 330 ------------CPQGYQLDSSQLDCVDVDEC----QDSPCAQECVNTPGGFRCECWVGY 373
CP GY+ D Q CVDVDEC D +Q+C N PG ++C C GY
Sbjct: 97 PPPVPPAQHPNPCPPGYEPDD-QDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGY 155
Query: 374 EPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVG 433
GP C D+DEC C C N GSF C CE G+ L G + C DV+EC
Sbjct: 156 RKIGP---ECVDIDECRYRY--CQHRCVNLPGSFRCQCEPGFQL-GPNNRSCVDVNEC-D 208
Query: 434 PGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSCT 468
G P C+ CFN+ G+F C C G+ L +G SC+
Sbjct: 209 MGAP-CEQRCFNSYGTFLCRCHQGYELHRDGFSCS 242
Score = 100 bits (248), Expect = 5e-21
Identities = 58/154 (37%), Positives = 70/154 (45%), Gaps = 15/154 (9%)
Query: 281 GSFLCGCRPGFRLLDDLVTCASRNPCS-SSPCRGGATCVLGPHGKNYTCRCPQGYQLDSS 339
GSF C C PGF+L + +C N C +PC G + CRC QGY+L
Sbjct: 182 GSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQRCFNSYG----TFLCRCHQGYELHRD 237
Query: 340 QLDCVDVDECQDSP--CAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPC- 396
C D+DEC S C CVN PG F C C GY+ CQD+DEC G C
Sbjct: 238 GFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQL--LATRLCQDIDECESGAHQCS 295
Query: 397 -AQGCTNTDGSFHC----SCEEGYVLAGEDGTQC 425
AQ C N G + C C E Y+ E+ C
Sbjct: 296 EAQTCVNFHGGYRCVDTNRCVEPYIQVSENRCLC 329
Score = 95.9 bits (237), Expect = 1e-19
Identities = 63/187 (33%), Positives = 81/187 (43%), Gaps = 43/187 (22%)
Query: 325 NYTCRCPQGYQLDSSQLDCVDVDECQDSPCA----QECVNTPGGFRC------------- 367
+YT C GY+ D C DV+EC P A +C+N GG+ C
Sbjct: 35 SYT-ECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLHG 93
Query: 368 --------------ECWVGYEPGGPGEGACQDVDECALGRSPC--AQGCTNTDGSFHCSC 411
C GYEP + +C DVDECA C +Q C N GS+ C+C
Sbjct: 94 EGPPPPVPPAQHPNPCPPGYEPDD--QDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTC 151
Query: 412 EEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSCT-MG 470
+GY + G +C D+DEC C C N GSF C C PG+ L PN SC +
Sbjct: 152 PDGY---RKIGPECVDIDEC---RYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVN 205
Query: 471 PVSLGPP 477
+G P
Sbjct: 206 ECDMGAP 212
Score = 74.7 bits (182), Expect = 2e-13
Identities = 43/101 (42%), Positives = 56/101 (55%), Gaps = 8/101 (7%)
Query: 271 CHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRC 330
C Q CF G+FLC C G+ L D +C+ + CS S CV P ++C C
Sbjct: 213 CEQRCFNSY-GTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEP--GRFSCHC 269
Query: 331 PQGYQLDSSQLDCVDVDECQDS--PC--AQECVNTPGGFRC 367
PQGYQL +++L C D+DEC+ C AQ CVN GG+RC
Sbjct: 270 PQGYQLLATRL-CQDIDECESGAHQCSEAQTCVNFHGGYRC 309
>gi|10190748 CEGP1 protein [Homo sapiens]
Length = 999
Score = 128 bits (322), Expect = 1e-29
Identities = 84/246 (34%), Positives = 111/246 (45%), Gaps = 40/246 (16%)
Query: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPC--------SSSPCRGGA 315
CN NGGC C + DG C C P +++ D +C R ++S G
Sbjct: 217 CNHGNGGCQHSCDDTADGPE-CSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGDK 275
Query: 316 ---------TCVLGPHGKNYTCR---------CPQGYQLDSSQLDCVDVDECQ--DSPCA 355
TC + G + TC+ CP G+ L C D+DECQ + C
Sbjct: 276 RVKRRLLMETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCD 335
Query: 356 QECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGY 415
C N G F C C G++ E +CQDVDEC+L R+ C C N G+F C+C GY
Sbjct: 336 HFCKNIVGSFDCGCKKGFKLL-TDEKSCQDVDECSLDRT-CDHSCINHPGTFACACNRGY 393
Query: 416 VLAGEDGTQCQDVDEC-VGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSCT----MG 470
L G T C D +EC + GG C +C NT GS+ C C PG+ L N C +
Sbjct: 394 TLYGF--THCGDTNECSINNGG--CQQVCVNTVGSYECQCHPGYKLHWNKKDCVEVKGLL 449
Query: 471 PVSLGP 476
P S+ P
Sbjct: 450 PTSVSP 455
Score = 109 bits (272), Expect = 9e-24
Identities = 71/235 (30%), Positives = 93/235 (39%), Gaps = 35/235 (14%)
Query: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNP----CSSSPCRGGATCVL 319
C NNGGC C GS+ C C+ GF L D+ TC R+ C + C
Sbjct: 132 CLENNGGCQHTCVNVM-GSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKE 190
Query: 320 GPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPG 379
P G + C C G++L +Q DC+ + C C +T G C C Y+ G
Sbjct: 191 APRG-SVACECRPGFELAKNQRDCILTCNHGNGGCQHSCDDTADGPECSCHPQYKMHTDG 249
Query: 380 EGACQDVD---------------------------ECALGRSPCAQGCTNTDGSFHCSCE 412
+ D CA+ C + C +T HCSC
Sbjct: 250 RSCLEREDTVLEVTESNTTSVVDGDKRVKRRLLMETCAVNNGGCDRTCKDTSTGVHCSCP 309
Query: 413 EGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
G+ L DG C+D+DEC G CD C N GSF CGC G+ L + SC
Sbjct: 310 VGFTLQ-LDGKTCKDIDECQTRNGG-CDHFCKNIVGSFDCGCKKGFKLLTDEKSC 362
Score = 106 bits (264), Expect = 8e-23
Identities = 66/191 (34%), Positives = 87/191 (45%), Gaps = 15/191 (7%)
Query: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHG 323
C NNGGC + C + G C C GF L D TC + C + GG
Sbjct: 286 CAVNNGGCDRTCKDTSTGVH-CSCPVGFTLQLDGKTCKDIDECQTR--NGGCDHFCKNIV 342
Query: 324 KNYTCRCPQGYQLDSSQLDCVDVDECQ-DSPCAQECVNTPGGFRCECWVGYEPGGPGEGA 382
++ C C +G++L + + C DVDEC D C C+N PG F C C GY G
Sbjct: 343 GSFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDHSCINHPGTFACACNRGYTLYGFTH-- 400
Query: 383 CQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSL 442
C D +EC++ C Q C NT GS+ C C GY L + +CV G L S+
Sbjct: 401 CGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLH-------WNKKDCVEVKGLLPTSV 453
Query: 443 CFNTQGSFHCG 453
+ + S HCG
Sbjct: 454 --SPRVSLHCG 462
Score = 100 bits (250), Expect = 3e-21
Identities = 58/172 (33%), Positives = 77/172 (44%), Gaps = 25/172 (14%)
Query: 311 CRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDS---PCAQECVNTPGGFRC 367
C A C P +Y C C GYQ + Q C D+DEC + C +C+N PG +RC
Sbjct: 56 CHADALCQNTP--TSYKCSCKPGYQGEGRQ--CEDIDECGNELNGGCVHDCLNIPGNYRC 111
Query: 368 ECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLA--------- 418
C+ G+ G C DVDEC C C N GS+ C C+EG+ L+
Sbjct: 112 TCFDGFMLAHDGHN-CLDVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTCIHR 170
Query: 419 GEDGTQCQDVDECVGPGGPLCDSLCFNT-QGSFHCGCLPGWVLAPNGVSCTM 469
E+G C + D C +C +GS C C PG+ LA N C +
Sbjct: 171 SEEGLSCMNKDHG-------CSHICKEAPRGSVACECRPGFELAKNQRDCIL 215
Score = 85.1 bits (209), Expect = 2e-16
Identities = 50/140 (35%), Positives = 70/140 (50%), Gaps = 23/140 (16%)
Query: 330 CPQGYQLDSSQLDCVDVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEG-ACQDVDE 388
C QG LD D + CQ++P + ++C C +PG GEG C+D+DE
Sbjct: 49 CAQG--LDDCHADAL----CQNTPTS---------YKCSC----KPGYQGEGRQCEDIDE 89
Query: 389 CALG-RSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQ 447
C C C N G++ C+C +G++LA DG C DVDEC+ G C C N
Sbjct: 90 CGNELNGGCVHDCLNIPGNYRCTCFDGFMLA-HDGHNCLDVDECLENNGG-CQHTCVNVM 147
Query: 448 GSFHCGCLPGWVLAPNGVSC 467
GS+ C C G+ L+ N +C
Sbjct: 148 GSYECCCKEGFFLSDNQHTC 167
Score = 73.9 bits (180), Expect = 4e-13
Identities = 41/96 (42%), Positives = 52/96 (54%), Gaps = 6/96 (6%)
Query: 375 PG-GPGEGACQDVDECALGRSPCAQG--CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDEC 431
PG G G +DVDECA G C C NT S+ CSC+ GY GE G QC+D+DEC
Sbjct: 34 PGRGRAAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGY--QGE-GRQCEDIDEC 90
Query: 432 VGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
C C N G++ C C G++LA +G +C
Sbjct: 91 GNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNC 126
Score = 73.9 bits (180), Expect = 4e-13
Identities = 61/223 (27%), Positives = 85/223 (38%), Gaps = 52/223 (23%)
Query: 271 CHQDCF-EGGDGSFLCGCRPGF----RLLDDLVTCASRNPCSSSPCRGGAT--CVLGPHG 323
CH D + S+ C C+PG+ R +D+ C + GG C+ P
Sbjct: 56 CHADALCQNTPTSYKCSCKPGYQGEGRQCEDIDECGNE-------LNGGCVHDCLNIP-- 106
Query: 324 KNYTCRCPQGYQLDSSQLDCVDVDEC--QDSPCAQECVNTPGGFRCECWVGYEPGGPGEG 381
NY C C G+ L +C+DVDEC + C CVN G + C C G+
Sbjct: 107 GNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYECCCKEGF-------- 158
Query: 382 ACQDVDECALGRSPCAQGCTNTD------------GSFHCSCEEGYVLAGEDGTQCQDVD 429
D + RS C N D GS C C G+ LA ++
Sbjct: 159 FLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELA-------KNQR 211
Query: 430 ECV-----GPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
+C+ G GG C C +T C C P + + +G SC
Sbjct: 212 DCILTCNHGNGG--CQHSCDDTADGPECSCHPQYKMHTDGRSC 252
>gi|4557733 latent transforming growth factor beta binding protein 2
[Homo sapiens]
Length = 1821
Score = 128 bits (321), Expect = 2e-29
Identities = 84/207 (40%), Positives = 110/207 (53%), Gaps = 19/207 (9%)
Query: 269 GGCHQDCFEGGDGSFLC-GCRPGFRLLDDLVTCASRNPCSS--SPCRGG-ATCVLGPHGK 324
G C GSF C C G+R +C + C S C GG +G
Sbjct: 1101 GVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVG---- 1156
Query: 325 NYTCRCPQGYQLDSSQLDCVDVDECQ-DSPCAQ--ECVNTPGGFRCECWVGYEPGGPGEG 381
+Y C CPQG+QL + + C DV+EC + CA EC+N+ G F C C G+ G
Sbjct: 1157 SYQCLCPQGFQLANGTV-CEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFV-SAEGGT 1214
Query: 382 ACQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCD 440
+CQDVDECA PC G C NT+GSF+C CE G+ + E G +C D+DEC G P+C
Sbjct: 1215 SCQDVDECAT-TDPCVGGHCVNTEGSFNCLCETGFQPSPESG-ECVDIDECEDYGDPVCG 1272
Query: 441 S-LCFNTQGSFHC--GCLPGWVLAPNG 464
+ C N+ GS+ C GC PG+ +APNG
Sbjct: 1273 TWKCENSPGSYRCVLGCQPGFHMAPNG 1299
Score = 127 bits (318), Expect = 4e-29
Identities = 86/195 (44%), Positives = 106/195 (54%), Gaps = 17/195 (8%)
Query: 280 DGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTC-RCPQGYQLDS 338
+GS+ C C G+ ++ C N C CV P +YTC C +GY+ S
Sbjct: 949 EGSYHCECDQGYIMVRK-GHCQDINECRHPGTCPDGRCVNSPG--SYTCLACEEGYRGQS 1005
Query: 339 SQLDCVDVDEC-QDSPCAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPC 396
CVDV+EC CA +C N G FRC C GYE +G CQDVDECA R+ C
Sbjct: 1006 GS--CVDVNECLTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKG-CQDVDECA-SRASC 1061
Query: 397 AQG-CTNTDGSFHCS-CEEGYVLAGEDGTQCQDVDECVGPGGPLCDS-LCFNTQGSFHC- 452
G C NT+GSF CS CE GY + EDGT C+D+DEC PG +C S +C NT GSF C
Sbjct: 1062 PTGLCLNTEGSFACSACENGYWV-NEDGTACEDLDECAFPG--VCPSGVCTNTAGSFSCK 1118
Query: 453 GCLPGWVLAPNGVSC 467
C G+ +P G SC
Sbjct: 1119 DCDGGYRPSPLGDSC 1133
Score = 121 bits (304), Expect = 2e-27
Identities = 84/238 (35%), Positives = 109/238 (45%), Gaps = 52/238 (21%)
Query: 275 CFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGY 334
C DG + C C PG++L C N C PC+G C+ +Y+C C GY
Sbjct: 861 CVNLPDG-YRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCI--NRVGSYSCFCYPGY 917
Query: 335 QLDSS--QLDCVDVDEC-QDSPCA-QECVNTPGGFRCECWVGY---------------EP 375
L +S +C D++EC Q C+ +C NT G + CEC GY P
Sbjct: 918 TLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQGYIMVRKGHCQDINECRHP 977
Query: 376 G---------GPG--------------EGACQDVDECALGRSPCAQG-CTNTDGSFHCSC 411
G PG G+C DV+EC L CA G CTN +GSF CSC
Sbjct: 978 GTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNEC-LTPGVCAHGKCTNLEGSFRCSC 1036
Query: 412 EEGYVLAGEDGTQCQDVDECVGPGGPLCDS-LCFNTQGSFHC-GCLPGWVLAPNGVSC 467
E+GY + D CQDVDEC C + LC NT+GSF C C G+ + +G +C
Sbjct: 1037 EQGYEVT-SDEKGCQDVDECASRAS--CPTGLCLNTEGSFACSACENGYWVNEDGTAC 1091
Score = 112 bits (281), Expect = 8e-25
Identities = 73/196 (37%), Positives = 94/196 (47%), Gaps = 17/196 (8%)
Query: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSP-CRGGATCVLGPHGKNYTCRCPQGYQLDSS 339
GS+ C C GF+L + V C N C C C L HG ++ C C G+
Sbjct: 1156 GSYQCLCPQGFQLANGTV-CEDVNECMGEEHCAPHGEC-LNSHG-SFFCLCAPGFVSAEG 1212
Query: 340 QLDCVDVDECQDS-PCAQ-ECVNTPGGFRCECWVGYEPGGPGEGACQDVDECA-LGRSPC 396
C DVDEC + PC CVNT G F C C G++P P G C D+DEC G C
Sbjct: 1213 GTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETGFQPS-PESGECVDIDECEDYGDPVC 1271
Query: 397 AQG-CTNTDGSFHC--SCEEGYVLAGEDGTQCQDVDECVGPGGPLCDS--LCFNTQGSFH 451
C N+ GS+ C C+ G+ +A C D+DEC +C S C NT GSF
Sbjct: 1272 GTWKCENSPGSYRCVLGCQPGFHMAPNG--DCIDIDECAND--TMCGSHGFCDNTDGSFR 1327
Query: 452 CGCLPGWVLAPNGVSC 467
C C G+ ++P+G C
Sbjct: 1328 CLCDQGFEISPSGWDC 1343
Score = 112 bits (279), Expect = 1e-24
Identities = 61/157 (38%), Positives = 80/157 (50%), Gaps = 12/157 (7%)
Query: 311 CRGGATCVLGPHG-----KNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQE--CVNTPG 363
C GAT V GP Y C C GYQL SQ C D +EC PC + C+N G
Sbjct: 848 CAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCINRVG 907
Query: 364 GFRCECWVGYEPGGPGEGA-CQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDG 422
+ C C+ GY G CQD++EC CTNT+GS+HC C++GY++ +
Sbjct: 908 SYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQGYIMVRKG- 966
Query: 423 TQCQDVDECVGPGGPLCDSLCFNTQGSFHC-GCLPGW 458
CQD++EC P G D C N+ GS+ C C G+
Sbjct: 967 -HCQDINECRHP-GTCPDGRCVNSPGSYTCLACEEGY 1001
Score = 108 bits (271), Expect = 1e-23
Identities = 78/211 (36%), Positives = 94/211 (44%), Gaps = 26/211 (12%)
Query: 269 GGCHQDCFEGGDGSFLC-GCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGK--- 324
G C GS+ C C G+R +C N C + C HGK
Sbjct: 978 GTCPDGRCVNSPGSYTCLACEEGYR--GQSGSCVDVNECLTP-----GVCA---HGKCTN 1027
Query: 325 ---NYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQE--CVNTPGGFRCE-CWVGYEPGGP 378
++ C C QGY++ S + C DVDEC C+NT G F C C GY
Sbjct: 1028 LEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFACSACENGYWVNED 1087
Query: 379 GEGACQDVDECALGRSPCAQG-CTNTDGSFHC-SCEEGYVLAGEDGTQCQDVDECVGPGG 436
G AC+D+DECA C G CTNT GSF C C+ GY G C+DVDEC P
Sbjct: 1088 GT-ACEDLDECAFP-GVCPSGVCTNTAGSFSCKDCDGGY-RPSPLGDSCEDVDECEDPQS 1144
Query: 437 PLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
C NT GS+ C C G+ LA NG C
Sbjct: 1145 SCLGGECKNTVGSYQCLCPQGFQLA-NGTVC 1174
Score = 64.7 bits (156), Expect = 3e-10
Identities = 63/243 (25%), Positives = 86/243 (35%), Gaps = 63/243 (25%)
Query: 277 EGGDGSFLC--GCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGY 334
E GS+ C GC+PGF + + C + C++ G G ++ C C QG+
Sbjct: 1277 ENSPGSYRCVLGCQPGFHMAPN-GDCIDIDECANDTMCGSHGFCDNTDG-SFRCLCDQGF 1334
Query: 335 QLDSSQLDCVDVDECQD--SPC-AQECVNTPGGFRCECWVGYEPGGPGEGAC-------Q 384
++ S DCVDV+EC+ + C A C N G F C C E EG C Q
Sbjct: 1335 EISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQ 1394
Query: 385 DVDECALG-----------------RSPCAQGCTNTDGSFHCSCEEGY-------VLAGE 420
+ E G +PC+ C C +G + E
Sbjct: 1395 SMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQGASWGDACDLCPSE 1454
Query: 421 DG------------------------TQCQDVDECVGPGGPLC-DSLCFNTQGSFHCGCL 455
D T D DECV G LC + C NT + C C
Sbjct: 1455 DSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCN 1514
Query: 456 PGW 458
PG+
Sbjct: 1515 PGF 1517
Score = 60.1 bits (144), Expect = 6e-09
Identities = 77/270 (28%), Positives = 97/270 (35%), Gaps = 55/270 (20%)
Query: 220 AANVACGE-GDKDETQSHY-FLCKEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFE 277
A + CG G D T + LC + F+ SG CV C C E
Sbjct: 1308 ANDTMCGSHGFCDNTDGSFRCLCDQG----FEISPSGWDCVDVNE-CELMLAVCGAALCE 1362
Query: 278 GGDGSFLCGCRPGFRLLD----------------------DLVTCASRNPCSSSPCRGGA 315
+GSFLC C D D +R C S +G A
Sbjct: 1363 NVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQ-KGHA 1421
Query: 316 TC--VLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQECVNTPGGFRCECWVGY 373
C VLG + C C QG +S D D+ +DS E C GY
Sbjct: 1422 PCSSVLGRNTTQAECCCTQG----ASWGDACDLCPSEDSAEFSEI--------CPSGKGY 1469
Query: 374 EPGGP----GEGACQDVDECAL-GRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQD 427
P G+ D DEC + G C G C NT + C C G+ +C+D
Sbjct: 1470 IPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASH-KKCED 1528
Query: 428 VDECVGPGGPLCDS-LCFNTQGSFHCGCLP 456
DEC C++ C NT+GSFHC C P
Sbjct: 1529 HDECQDLA---CENGECVNTEGSFHCFCSP 1555
Score = 55.1 bits (131), Expect = 2e-07
Identities = 28/63 (44%), Positives = 36/63 (57%), Gaps = 8/63 (12%)
Query: 324 KNYTCRCPQGYQLDSSQLDCVDVDECQD--SPCA----QECVNTPGGFRCECWVGY--EP 375
+ YTC C +G+QLD++ + CVDV+EC D P C NT G +RC C GY E
Sbjct: 1753 EGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRCHCSPGYVAEA 1812
Query: 376 GGP 378
G P
Sbjct: 1813 GPP 1815
Score = 53.5 bits (127), Expect = 6e-07
Identities = 48/194 (24%), Positives = 65/194 (33%), Gaps = 32/194 (16%)
Query: 185 KGMCRPLALGGPGQVTYTTPFQTTSSSLEAVPFASAANVACGEGDKDETQSHYFLCKEKA 244
+G CRP GG T + + + C T C + A
Sbjct: 1383 EGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQGA 1442
Query: 245 PDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRN 304
WG + LC S + + S +C G+ ++ T
Sbjct: 1443 ----SWGDACDLCPSE----------------DSAEFSEICPSGKGYIPVEGAWTFGQTM 1482
Query: 305 PCSSSPCR--GGATCVLGPHGK------NYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQ 356
+ C G C P+G+ Y C C G+ D+S C D DECQD C
Sbjct: 1483 YTDADECVIFGPGLC---PNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDECQDLACEN 1539
Query: 357 -ECVNTPGGFRCEC 369
ECVNT G F C C
Sbjct: 1540 GECVNTEGSFHCFC 1553
Score = 53.1 bits (126), Expect = 8e-07
Identities = 37/120 (30%), Positives = 55/120 (45%), Gaps = 13/120 (10%)
Query: 301 ASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQECVN 360
A R P SP + L PH P G++ ++ +C ++ C++ CV
Sbjct: 1699 ADRTPILESPLQPSE---LQPHYVASHPEPPAGFEGLQAE-ECGILNGCENG----RCVR 1750
Query: 361 TPGGFRCECWVGYEPGGPGEGACQDVDECALGRSP---CAQG-CTNTDGSFHCSCEEGYV 416
G+ C+C+ G++ AC DV+EC P C G C NT+GS+ C C GYV
Sbjct: 1751 VREGYTCDCFEGFQLDA-AHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRCHCSPGYV 1809
Score = 51.6 bits (122), Expect = 2e-06
Identities = 34/103 (33%), Positives = 44/103 (42%), Gaps = 6/103 (5%)
Query: 370 WVGYEPGGPGEGACQDVDECALGRSPCAQG-CTNTDGSFHCSCEEGYVLAGEDGTQCQDV 428
+V P P +EC + + C G C + C C EG+ L C DV
Sbjct: 1718 YVASHPEPPAGFEGLQAEECGI-LNGCENGRCVRVREGYTCDCFEGFQLDAAH-MACVDV 1775
Query: 429 DECVGPGGP--LC-DSLCFNTQGSFHCGCLPGWVLAPNGVSCT 468
+EC GP LC C NT+GS+ C C PG+V CT
Sbjct: 1776 NECDDLNGPAVLCVHGYCENTEGSYRCHCSPGYVAEAGPPHCT 1818
Score = 46.6 bits (109), Expect = 7e-05
Identities = 25/58 (43%), Positives = 34/58 (58%), Gaps = 5/58 (8%)
Query: 411 CEEGYVLAGEDGTQCQDVDECVGPGGPLC-DSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
C +GY T CQD++EC+ G LC D+ C NT+GS+ C C PG +L P+ C
Sbjct: 608 CPQGYKRLNL--THCQDINECLTLG--LCKDAECVNTRGSYLCTCRPGLMLDPSRSRC 661
Score = 40.8 bits (94), Expect = 0.004
Identities = 60/254 (23%), Positives = 86/254 (33%), Gaps = 50/254 (19%)
Query: 265 NFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGK 324
N NG C E CG F + CA PC P P +
Sbjct: 557 NTVNGQCANPLLELTTQEDCCGSVGAFW---GVTLCA---PCPPRPA--------SPVIE 602
Query: 325 NYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQ--ECVNTPGGFRCECWVGYEPG---GPG 379
N CPQGY+ + C D++EC + ECVNT G + C C PG P
Sbjct: 603 NGQLECPQGYKR-LNLTHCQDINECLTLGLCKDAECVNTRGSYLCTC----RPGLMLDPS 657
Query: 380 EGAC---------QDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDE 430
C Q + +LG C C C + G++C ++
Sbjct: 658 RSRCVSDKAISMLQGLCYRSLGPGTCTLPLAQRITKQICCCSR---VGKAWGSEC---EK 711
Query: 431 CVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSCTMGPVSLGPPSGPPDEEDKGEKE 490
C PG +C + H G+ A + + +M + PP E+ G++
Sbjct: 712 CPLPGTEAFREIC----PAGH-----GYTYASSDIRLSMRKAEEEELARPPREQ--GQRS 760
Query: 491 GSTVPRAATASPTR 504
+P A P R
Sbjct: 761 SGALPGPAERQPLR 774
Score = 33.5 bits (75), Expect = 0.63
Identities = 39/171 (22%), Positives = 55/171 (32%), Gaps = 35/171 (20%)
Query: 195 GPGQVTYT------TPFQTTSSSLEAVPFASAANVACGEGDK----------DETQSHYF 238
GP + Y+ PF + VP + N A D+ E Q HY
Sbjct: 1660 GPDDLHYSIYGPDGAPFYNYLGPEDTVPEPAFPNTAGHSADRTPILESPLQPSELQPHYV 1719
Query: 239 LCKEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLV 298
+ P F+ + C NG + C +G + C C GF+L +
Sbjct: 1720 ASHPEPPAGFEGLQAEE--------CGILNGCENGRCVRVREG-YTCDCFEGFQLDAAHM 1770
Query: 299 TCASRNPCSSSPCRGGATCVLGPHG------KNYTCRCPQGYQLDSSQLDC 343
C N C VL HG +Y C C GY ++ C
Sbjct: 1771 ACVDVNECDDL----NGPAVLCVHGYCENTEGSYRCHCSPGYVAEAGPPHC 1817
Score = 30.8 bits (68), Expect = 4.1
Identities = 13/42 (30%), Positives = 18/42 (42%), Gaps = 1/42 (2%)
Query: 428 VDECVGPGGPLCD-SLCFNTQGSFHCGCLPGWVLAPNGVSCT 468
+D C +C C N + C C PG+ L P+ CT
Sbjct: 845 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCT 886
>gi|51873055 fibulin 2 isoform b precursor [Homo sapiens]
Length = 1184
Score = 127 bits (319), Expect = 3e-29
Identities = 82/207 (39%), Positives = 107/207 (51%), Gaps = 30/207 (14%)
Query: 281 GSFLCG----CRPGFRLLDDLVTCASRNPCSS--SPCRGGATCV--LGPHGKNYTCR--- 329
GSF C C GF L D C N C+S PCR G +C+ +G +YTC+
Sbjct: 786 GSFYCQARQRCMDGF-LQDPEGNCVDINECTSLSEPCRPGFSCINTVG----SYTCQRNP 840
Query: 330 --CPQGYQLDSSQLDCVDVDECQDSP--CA--QECVNTPGGFRCECWVGYEPGGPGEGAC 383
C +GY CVDV+EC+ C Q C N PG +RC+C G++ G G C
Sbjct: 841 LICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRG-C 899
Query: 384 QDVDEC--ALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDS 441
DV+EC + GR C C NT GS+ CSC G++LA DG +C+DV+EC C
Sbjct: 900 IDVNECWASPGRL-CQHTCENTLGSYRCSCASGFLLAA-DGKRCEDVNECEAQR---CSQ 954
Query: 442 LCFNTQGSFHCGCLPGWVLAPNGVSCT 468
C N GS+ C C G+ LA +G +CT
Sbjct: 955 ECANIYGSYQCYCRQGYQLAEDGHTCT 981
Score = 117 bits (293), Expect = 3e-26
Identities = 70/188 (37%), Positives = 93/188 (49%), Gaps = 15/188 (7%)
Query: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSP---CRGGATCVLGPHGKNYTCRCPQGYQLD 337
GS+ C C+ GF+ C N C +SP C+ LG +Y C C G+ L
Sbjct: 880 GSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLG----SYRCSCASGFLLA 935
Query: 338 SSQLDCVDVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRS-PC 396
+ C DV+EC+ C+QEC N G ++C C GY+ G C D+DECA G C
Sbjct: 936 ADGKRCEDVNECEAQRCSQECANIYGSYQCYCRQGYQLAEDGH-TCTDIDECAQGAGILC 994
Query: 397 AQGCTNTDGSFHCSC-EEGYVLAGEDGTQCQDVDEC-VGPGGPLCDSLCFNTQGSFHC-- 452
C N GS+ C+C E+GY + +G C+DVDEC +G C N QGSF C
Sbjct: 995 TFRCLNVPGSYQCACPEQGYTMTA-NGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLR 1053
Query: 453 -GCLPGWV 459
C P +V
Sbjct: 1054 FECPPNYV 1061
Score = 112 bits (281), Expect = 8e-25
Identities = 78/261 (29%), Positives = 104/261 (39%), Gaps = 64/261 (24%)
Query: 267 NNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPC-------------------- 306
+NG C Q C G GS +C C PG+ ++ D V+C N C
Sbjct: 685 DNGPCKQVCSTVG-GSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSF 743
Query: 307 --------------SSSPCRGGATCVLGPHG--KNYTC-------------RCPQGYQLD 337
C C +G H + C RC G+ L
Sbjct: 744 HCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF-LQ 802
Query: 338 SSQLDCVDVDECQD--SPCAQ--ECVNTPGGFRCE-----CWVGYEPGGPGEGACQDVDE 388
+ +CVD++EC PC C+NT G + C+ C GY G C DV+E
Sbjct: 803 DPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGT-KCVDVNE 861
Query: 389 CALGRSPCAQG--CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNT 446
C G C +G C N GS+ C C+ G+ G C DV+EC G LC C NT
Sbjct: 862 CETGVHRCGEGQVCHNLPGSYRCDCKAGFQ-RDAFGRGCIDVNECWASPGRLCQHTCENT 920
Query: 447 QGSFHCGCLPGWVLAPNGVSC 467
GS+ C C G++LA +G C
Sbjct: 921 LGSYRCSCASGFLLAADGKRC 941
Score = 107 bits (267), Expect = 3e-23
Identities = 75/219 (34%), Positives = 92/219 (42%), Gaps = 20/219 (9%)
Query: 225 CGEGDKDETQSHYFLCKEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFL 284
CGEG + C KA F + G C+ C + G Q E GS+
Sbjct: 869 CGEGQVCHNLPGSYRCDCKAG--FQRDAFGRGCIDVNE-CWASPGRLCQHTCENTLGSYR 925
Query: 285 CGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCV 344
C C GF L D C N C + C + G +Y C C QGYQL C
Sbjct: 926 CSCASGFLLAADGKRCEDVNECEAQRCSQECANIYG----SYQCYCRQGYQLAEDGHTCT 981
Query: 345 DVDECQDSP---CAQECVNTPGGFRCEC-WVGYEPGGPGEGACQDVDECALGRSPC--AQ 398
D+DEC C C+N PG ++C C GY G +C+DVDECALG C A+
Sbjct: 982 DIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGR-SCKDVDECALGTHNCSEAE 1040
Query: 399 GCTNTDGSFHC---SCEEGYVLAGE---DGTQCQDVDEC 431
C N GSF C C YV + + T C D EC
Sbjct: 1041 TCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLEC 1079
Score = 102 bits (253), Expect = 1e-21
Identities = 74/234 (31%), Positives = 99/234 (42%), Gaps = 49/234 (20%)
Query: 281 GSFLCGCRPGFRLLDDLVTC----------ASRNPCSSS------------------PCR 312
GS+ C C PGF L DD TC A + P S C+
Sbjct: 625 GSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPLPQPNTCK 684
Query: 313 GGATC--VLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDS--PCA--QECVNTPGGFR 366
C V G + C C GY + + + C D++EC C+ + CVNT G F
Sbjct: 685 DNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFH 744
Query: 367 CECWVGYEPG-GPGEGACQDVDECALGRSPCAQG--CTNTDGSFHCS----CEEGYVLAG 419
C + EPG +G C+DVDECA+G C G C NT GSF+C C +G++
Sbjct: 745 CYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDP 804
Query: 420 EDGTQCQDVDECVGPGGPLCDSL-CFNTQGSFHCG-----CLPGWVLAPNGVSC 467
E C D++EC P C NT GS+ C C G+ + +G C
Sbjct: 805 EG--NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKC 856
Score = 66.6 bits (161), Expect = 7e-11
Identities = 51/175 (29%), Positives = 64/175 (36%), Gaps = 44/175 (25%)
Query: 345 DVDECQDSP---CAQECVNTPGGFRCECWVGY----------------EPGGPGEGACQD 385
D DEC P C C+NT G + C C+ G+ +P P E A +
Sbjct: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKS 663
Query: 386 ---------------VDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDE 430
PC Q C+ GS CSC GY + DG C+D++E
Sbjct: 664 EFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMA-DGVSCEDINE 722
Query: 431 CVGPGGPLC-DSLCFNTQGSFHC----GCLPGWVLAPNGV----SCTMGPVSLGP 476
CV C NT GSFHC C PG+ L C MG + P
Sbjct: 723 CVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQP 777
Score = 52.8 bits (125), Expect = 1e-06
Identities = 25/58 (43%), Positives = 30/58 (51%), Gaps = 7/58 (12%)
Query: 427 DVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSCTMGPVSLGPPSGPPDEE 484
D DEC+ G LC LC NT GS+HC C PG+ L +G +C P PP E
Sbjct: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCR-------PEGHPPQPE 654
Score = 50.4 bits (119), Expect = 5e-06
Identities = 36/129 (27%), Positives = 46/129 (35%), Gaps = 33/129 (25%)
Query: 371 VGYEPGGPGEGACQDVDECALGRSP-CAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVD 429
+G E P D DEC L C C NT GS+HC+C G+ L +DG C+
Sbjct: 590 LGTEAELPNSLPGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQ-DDGRTCRPEG 648
Query: 430 ECVGPGGPL-------------------------------CDSLCFNTQGSFHCGCLPGW 458
P P C +C GS C C PG+
Sbjct: 649 HPPQPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGY 708
Query: 459 VLAPNGVSC 467
+ +GVSC
Sbjct: 709 AIMADGVSC 717
>gi|51873053 fibulin 2 isoform a precursor [Homo sapiens]
Length = 1231
Score = 127 bits (319), Expect = 3e-29
Identities = 82/207 (39%), Positives = 107/207 (51%), Gaps = 30/207 (14%)
Query: 281 GSFLCG----CRPGFRLLDDLVTCASRNPCSS--SPCRGGATCV--LGPHGKNYTCR--- 329
GSF C C GF L D C N C+S PCR G +C+ +G +YTC+
Sbjct: 833 GSFYCQARQRCMDGF-LQDPEGNCVDINECTSLSEPCRPGFSCINTVG----SYTCQRNP 887
Query: 330 --CPQGYQLDSSQLDCVDVDECQDSP--CA--QECVNTPGGFRCECWVGYEPGGPGEGAC 383
C +GY CVDV+EC+ C Q C N PG +RC+C G++ G G C
Sbjct: 888 LICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRG-C 946
Query: 384 QDVDEC--ALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDS 441
DV+EC + GR C C NT GS+ CSC G++LA DG +C+DV+EC C
Sbjct: 947 IDVNECWASPGRL-CQHTCENTLGSYRCSCASGFLLAA-DGKRCEDVNECEAQR---CSQ 1001
Query: 442 LCFNTQGSFHCGCLPGWVLAPNGVSCT 468
C N GS+ C C G+ LA +G +CT
Sbjct: 1002 ECANIYGSYQCYCRQGYQLAEDGHTCT 1028
Score = 117 bits (293), Expect = 3e-26
Identities = 70/188 (37%), Positives = 93/188 (49%), Gaps = 15/188 (7%)
Query: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSP---CRGGATCVLGPHGKNYTCRCPQGYQLD 337
GS+ C C+ GF+ C N C +SP C+ LG +Y C C G+ L
Sbjct: 927 GSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLG----SYRCSCASGFLLA 982
Query: 338 SSQLDCVDVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRS-PC 396
+ C DV+EC+ C+QEC N G ++C C GY+ G C D+DECA G C
Sbjct: 983 ADGKRCEDVNECEAQRCSQECANIYGSYQCYCRQGYQLAEDGH-TCTDIDECAQGAGILC 1041
Query: 397 AQGCTNTDGSFHCSC-EEGYVLAGEDGTQCQDVDEC-VGPGGPLCDSLCFNTQGSFHC-- 452
C N GS+ C+C E+GY + +G C+DVDEC +G C N QGSF C
Sbjct: 1042 TFRCLNVPGSYQCACPEQGYTMTA-NGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLR 1100
Query: 453 -GCLPGWV 459
C P +V
Sbjct: 1101 FECPPNYV 1108
Score = 116 bits (291), Expect = 6e-26
Identities = 79/223 (35%), Positives = 111/223 (49%), Gaps = 26/223 (11%)
Query: 267 NNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPC--SSSPCRGGATCV--LGP- 321
+NG C Q C G GS +C C PG+ ++ D V+C ++ C + C CV LG
Sbjct: 685 DNGPCKQVCSTVG-GSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSF 743
Query: 322 HGKNYTCRCPQGYQLDSSQLDCVDVDECQDS--PCA--QECVNTPGGFRCECWVGYEPG- 376
+ N+T C GY L++ + CVD++EC C+ + CVNT G F C + EPG
Sbjct: 744 YCVNHTVLCADGYILNAHR-KCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGY 802
Query: 377 GPGEGACQDVDECALGRSPCAQG--CTNTDGSFHCS----CEEGYVLAGEDGTQCQDVDE 430
+G C+DVDECA+G C G C NT GSF+C C +G++ E C D++E
Sbjct: 803 ALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG--NCVDINE 860
Query: 431 CVGPGGPLCDSL-CFNTQGSFHCG-----CLPGWVLAPNGVSC 467
C P C NT GS+ C C G+ + +G C
Sbjct: 861 CTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKC 903
Score = 107 bits (267), Expect = 3e-23
Identities = 75/219 (34%), Positives = 92/219 (42%), Gaps = 20/219 (9%)
Query: 225 CGEGDKDETQSHYFLCKEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFL 284
CGEG + C KA F + G C+ C + G Q E GS+
Sbjct: 916 CGEGQVCHNLPGSYRCDCKAG--FQRDAFGRGCIDVNE-CWASPGRLCQHTCENTLGSYR 972
Query: 285 CGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCV 344
C C GF L D C N C + C + G +Y C C QGYQL C
Sbjct: 973 CSCASGFLLAADGKRCEDVNECEAQRCSQECANIYG----SYQCYCRQGYQLAEDGHTCT 1028
Query: 345 DVDECQDSP---CAQECVNTPGGFRCEC-WVGYEPGGPGEGACQDVDECALGRSPC--AQ 398
D+DEC C C+N PG ++C C GY G +C+DVDECALG C A+
Sbjct: 1029 DIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGR-SCKDVDECALGTHNCSEAE 1087
Query: 399 GCTNTDGSFHC---SCEEGYVLAGE---DGTQCQDVDEC 431
C N GSF C C YV + + T C D EC
Sbjct: 1088 TCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLEC 1126
Score = 106 bits (264), Expect = 8e-23
Identities = 71/206 (34%), Positives = 94/206 (45%), Gaps = 24/206 (11%)
Query: 281 GSFLC----GCRPGFRLLDDLVTCASRNPCS--SSPCRGGATC--VLGPHGKNYTCRCPQ 332
GSF C C PG+ L D C + C+ + C+ G C G RC
Sbjct: 788 GSFHCYKALTCEPGYALKDG--ECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMD 845
Query: 333 GYQLDSSQLDCVDVDECQD--SPCAQ--ECVNTPGGFRCE-----CWVGYEPGGPGEGAC 383
G+ L + +CVD++EC PC C+NT G + C+ C GY G C
Sbjct: 846 GF-LQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGT-KC 903
Query: 384 QDVDECALGRSPCAQG--CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDS 441
DV+EC G C +G C N GS+ C C+ G+ G C DV+EC G LC
Sbjct: 904 VDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQ-RDAFGRGCIDVNECWASPGRLCQH 962
Query: 442 LCFNTQGSFHCGCLPGWVLAPNGVSC 467
C NT GS+ C C G++LA +G C
Sbjct: 963 TCENTLGSYRCSCASGFLLAADGKRC 988
Score = 102 bits (255), Expect = 8e-22
Identities = 81/235 (34%), Positives = 101/235 (42%), Gaps = 57/235 (24%)
Query: 281 GSFLCGCRPGFRLLDDLVTC----------ASRNPCSSS------------------PCR 312
GS+ C C PGF L DD TC A + P S C+
Sbjct: 625 GSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPLPQPNTCK 684
Query: 313 GGATC--VLGPHGKNYTCRCPQGYQLDSSQLDCVDVDEC----QDSPCAQECVNTPGGFR 366
C V G + C C GY + + + C D DEC D Q CVNT G F
Sbjct: 685 DNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFY 744
Query: 367 CE-----CWVGYEPGGPGEGACQDVDECALGRSPCAQG--CTNTDGSFHC----SCEEGY 415
C C GY C D++EC C++G C NT GSFHC +CE GY
Sbjct: 745 CVNHTVLCADGYILN--AHRKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGY 802
Query: 416 VLAGEDGTQCQDVDECVGPGGPLCDS--LCFNTQGSFHC----GCLPGWVLAPNG 464
L +DG +C+DVDEC G C LC NT+GSF+C C+ G++ P G
Sbjct: 803 AL--KDG-ECEDVDEC-AMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG 853
Score = 64.7 bits (156), Expect = 3e-10
Identities = 47/157 (29%), Positives = 60/157 (38%), Gaps = 43/157 (27%)
Query: 345 DVDECQDSP---CAQECVNTPGGFRCECWVGY----------------EPGGPGEGACQD 385
D DEC P C C+NT G + C C+ G+ +P P E A +
Sbjct: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKS 663
Query: 386 ---------------VDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDE 430
PC Q C+ GS CSC GY + DG C+D DE
Sbjct: 664 EFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMA-DGVSCEDQDE 722
Query: 431 CVGPGGPLCD--SLCFNTQGSFHCG-----CLPGWVL 460
C+ G C C NT GSF+C C G++L
Sbjct: 723 CL-MGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYIL 758
Score = 52.8 bits (125), Expect = 1e-06
Identities = 25/58 (43%), Positives = 30/58 (51%), Gaps = 7/58 (12%)
Query: 427 DVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSCTMGPVSLGPPSGPPDEE 484
D DEC+ G LC LC NT GS+HC C PG+ L +G +C P PP E
Sbjct: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCR-------PEGHPPQPE 654
Score = 50.4 bits (119), Expect = 5e-06
Identities = 36/129 (27%), Positives = 46/129 (35%), Gaps = 33/129 (25%)
Query: 371 VGYEPGGPGEGACQDVDECALGRSP-CAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVD 429
+G E P D DEC L C C NT GS+HC+C G+ L +DG C+
Sbjct: 590 LGTEAELPNSLPGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQ-DDGRTCRPEG 648
Query: 430 ECVGPGGPL-------------------------------CDSLCFNTQGSFHCGCLPGW 458
P P C +C GS C C PG+
Sbjct: 649 HPPQPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGY 708
Query: 459 VLAPNGVSC 467
+ +GVSC
Sbjct: 709 AIMADGVSC 717
>gi|120587029 signal peptide, CUB domain, EGF-like 1 [Homo sapiens]
Length = 988
Score = 126 bits (316), Expect = 7e-29
Identities = 81/241 (33%), Positives = 105/241 (43%), Gaps = 51/241 (21%)
Query: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNP---------------CSS 308
C NNGGC Q C GS+ C C GF L D+ TC R+ C
Sbjct: 121 CQDNNGGCQQICVNAM-GSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRE 179
Query: 309 SP-------CRGG-----------ATCVLGPHGKNY---------TCRCPQGYQLDSSQL 341
+P CR G TC G G + TC C Q Y L S
Sbjct: 180 TPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGR 239
Query: 342 DCVDVDECQDSPCAQECVNTPGGFRCECWVGY--EPGGPGEGACQDVDECALGRSPCAQG 399
C++ + C + C +T G RC C VG+ +P G C+D++EC + C
Sbjct: 240 TCIETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGK---TCKDINECLVNNGGCDHF 296
Query: 400 CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWV 459
C NT GSF C C +GY L ++ T CQD+DEC CD +C N+ GSF C C G++
Sbjct: 297 CRNTVGSFECGCRKGYKLLTDERT-CQDIDEC--SFERTCDHICINSPGSFQCLCHRGYI 353
Query: 460 L 460
L
Sbjct: 354 L 354
Score = 116 bits (291), Expect = 6e-26
Identities = 75/245 (30%), Positives = 104/245 (42%), Gaps = 14/245 (5%)
Query: 252 SSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPC 311
S G C+ C NNGGC + C + G C C GF L D TC N C +
Sbjct: 236 SDGRTCIET---CAVNNGGCDRTCKDTATG-VRCSCPVGFTLQPDGKTCKDINECLVN-- 289
Query: 312 RGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQ-DSPCAQECVNTPGGFRCECW 370
GG ++ C C +GY+L + + C D+DEC + C C+N+PG F+C C
Sbjct: 290 NGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFERTCDHICINSPGSFQCLCH 349
Query: 371 VGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDE 430
GY G C DVDEC++ C QGC NT GS+ C C G L +G C + +
Sbjct: 350 RGYILYGTTH--CGDVDECSMSNGSCDQGCVNTKGSYECVCPPGRRLHW-NGKDCVETGK 406
Query: 431 CVGPG--GPLCDSLCFNTQGSFHC--GCLPGWVLAPNGVSCTMGPVSLGPPSGPPDEEDK 486
C+ P C G C C + P+ + + + P G ++
Sbjct: 407 CLSRAKTSPRAQLSCSKAGGVESCFLSCPAHTLFVPDSENSYVLSCGVPGPQGKALQKRN 466
Query: 487 GEKEG 491
G G
Sbjct: 467 GTSSG 471
Score = 103 bits (256), Expect = 6e-22
Identities = 72/247 (29%), Positives = 102/247 (41%), Gaps = 50/247 (20%)
Query: 265 NFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGK 324
++ NGGC +C G++ C C GF L D C + C + GG +
Sbjct: 81 DYYNGGCVHECINI-PGNYRCTCFDGFMLAHDGHNCLDVDECQDN--NGGCQQICVNAMG 137
Query: 325 NYTCRCPQGYQLDSSQLDCV----DVDEC--QDSPCAQECVNTP-GGFRCECWVGYEPG- 376
+Y C+C G+ L +Q C+ + C +D CA C TP GG C+C G++
Sbjct: 138 SYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQ 197
Query: 377 ---------GPGEGACQD--------------------------VDECALGRSPCAQGCT 401
G G CQ ++ CA+ C + C
Sbjct: 198 NQKDCTLTCNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTCIETCAVNNGGCDRTCK 257
Query: 402 NTDGSFHCSCEEGYVLAGEDGTQCQDVDEC-VGPGGPLCDSLCFNTQGSFHCGCLPGWVL 460
+T CSC G+ L DG C+D++EC V GG CD C NT GSF CGC G+ L
Sbjct: 258 DTATGVRCSCPVGFTLQ-PDGKTCKDINECLVNNGG--CDHFCRNTVGSFECGCRKGYKL 314
Query: 461 APNGVSC 467
+ +C
Sbjct: 315 LTDERTC 321
Score = 102 bits (254), Expect = 1e-21
Identities = 59/173 (34%), Positives = 78/173 (45%), Gaps = 26/173 (15%)
Query: 311 CRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDS----PCAQECVNTPGGFR 366
C A C P K+Y C C GY+ + Q C D+DEC++ C EC+N PG +R
Sbjct: 44 CHIDAICQNTP--KSYKCLCKPGYKGEGKQ--CEDIDECENDYYNGGCVHECINIPGNYR 99
Query: 367 CECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLA-------- 418
C C+ G+ G C DVDEC C Q C N GS+ C C G+ L+
Sbjct: 100 CTCFDGFMLAHDGHN-CLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIH 158
Query: 419 -GEDGTQCQDVDECVGPGGPLCDSLCFNT-QGSFHCGCLPGWVLAPNGVSCTM 469
+G C + D C +C T +G C C PG+ LA N CT+
Sbjct: 159 RSNEGMNCMNKDHG-------CAHICRETPKGGVACDCRPGFDLAQNQKDCTL 204
Score = 82.0 bits (201), Expect = 2e-15
Identities = 48/141 (34%), Positives = 70/141 (49%), Gaps = 24/141 (17%)
Query: 330 CPQGYQLDSSQLDCVDVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEG-ACQDVDE 388
C +G D +D + CQ++P + ++C C +PG GEG C+D+DE
Sbjct: 37 CSEG--TDDCHIDAI----CQNTPKS---------YKCLC----KPGYKGEGKQCEDIDE 77
Query: 389 CA--LGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNT 446
C C C N G++ C+C +G++LA DG C DVDEC G C +C N
Sbjct: 78 CENDYYNGGCVHECINIPGNYRCTCFDGFMLA-HDGHNCLDVDECQDNNGG-CQQICVNA 135
Query: 447 QGSFHCGCLPGWVLAPNGVSC 467
GS+ C C G+ L+ N +C
Sbjct: 136 MGSYECQCHSGFFLSDNQHTC 156
Score = 68.9 bits (167), Expect = 1e-11
Identities = 40/97 (41%), Positives = 51/97 (52%), Gaps = 10/97 (10%)
Query: 376 GGPGEGACQDVDECALGRSPCAQG--CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVG 433
GG G DVDEC+ G C C NT S+ C C+ GY GE G QC+D+DEC
Sbjct: 24 GGSGLPGSVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGY--KGE-GKQCEDIDECEN 80
Query: 434 P---GGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
GG C C N G++ C C G++LA +G +C
Sbjct: 81 DYYNGG--CVHECINIPGNYRCTCFDGFMLAHDGHNC 115
>gi|62548862 matrilin 2 isoform b precursor [Homo sapiens]
Length = 937
Score = 125 bits (314), Expect = 1e-28
Identities = 75/216 (34%), Positives = 106/216 (49%), Gaps = 11/216 (5%)
Query: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHG 323
C + GC Q C D SF+C C GF + +DL TC+ + C S +CV
Sbjct: 447 CAQQDHGCEQLCLNTED-SFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCV--NMD 503
Query: 324 KNYTCRCPQGYQLDSSQLDCVDVDECQ--DSPCAQECVNTPGGFRCECWVGYEPGGPGEG 381
+++ C+CP+G+ L S C +D C D C CV++ F C+C+ GY G+
Sbjct: 504 RSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGK- 562
Query: 382 ACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDS 441
C+ D C C C N+D S+ C C EG+ LA EDG +C+ D C C+
Sbjct: 563 TCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLA-EDGKRCRRKDVCKSTHHG-CEH 620
Query: 442 LCFNTQGSFHCGCLPGWVLAPNG---VSCTMGPVSL 474
+C N S+ C C G+VLA +G CT GP+ L
Sbjct: 621 ICVNNGNSYICKCSEGFVLAEDGRRCKKCTEGPIDL 656
Score = 121 bits (303), Expect = 2e-27
Identities = 63/190 (33%), Positives = 93/190 (48%), Gaps = 7/190 (3%)
Query: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQ 340
GS++C C+ G+ L D TC ++ C+ CV P ++ C+C GY L
Sbjct: 258 GSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVP--GSFVCQCYSGYALAEDG 315
Query: 341 LDCVDVDEC--QDSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQ 398
CV VD C ++ C ECVN G + C+C G+ P + C +D CA C
Sbjct: 316 KRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFAL-NPDKKTCTKIDYCASSNHGCQH 374
Query: 399 GCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGW 458
C NTD S+ C C +G+ L D C+ ++ C P C+ C N + S++C C G+
Sbjct: 375 ECVNTDDSYSCHCLKGFTL-NPDKKTCRRINYC-ALNKPGCEHECVNMEESYYCRCHRGY 432
Query: 459 VLAPNGVSCT 468
L PNG +C+
Sbjct: 433 TLDPNGKTCS 442
Score = 120 bits (302), Expect = 3e-27
Identities = 90/297 (30%), Positives = 117/297 (39%), Gaps = 89/297 (29%)
Query: 254 GPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSS---- 309
G CV+ Y C N GC +C DGS+LC C GF L D TC + C+SS
Sbjct: 315 GKRCVAVDY-CASENHGCEHECVNA-DGSYLCQCHEGFALNPDKKTCTKIDYCASSNHGC 372
Query: 310 --------------------------PCRGGATCVLGPHG---------KNYTCRCPQGY 334
CR C L G ++Y CRC +GY
Sbjct: 373 QHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGY 432
Query: 335 QLDSSQLDCVDVDEC--QDSPCAQECVNTPGGFRCECWVGYE------------------ 374
LD + C VD C QD C Q C+NT F C+C G+
Sbjct: 433 TLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSD 492
Query: 375 ------------------PGGP---GEG-ACQDVDECALGRSPCAQGCTNTDGSFHCSCE 412
P G +G C +D CALG C C +++ SF C C
Sbjct: 493 HGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCF 552
Query: 413 EGYVLAGEDGTQC--QDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
EGY+L EDG C +DV + + G C+ +C N+ S+ C CL G+ LA +G C
Sbjct: 553 EGYILR-EDGKTCRRKDVCQAIDHG---CEHICVNSDDSYTCECLEGFRLAEDGKRC 605
Score = 91.7 bits (226), Expect = 2e-18
Identities = 63/192 (32%), Positives = 82/192 (42%), Gaps = 14/192 (7%)
Query: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHG 323
C ++ GC C D SF C C G L D TCA + C+ +CV
Sbjct: 488 CLLSDHGCEYSCVNM-DRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSED- 545
Query: 324 KNYTCRCPQGYQLDSSQLDCVDVDECQ--DSPCAQECVNTPGGFRCECWVGYEPGGPGEG 381
++ C+C +GY L C D CQ D C CVN+ + CEC G+ G+
Sbjct: 546 -SFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGK- 603
Query: 382 ACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDS 441
C+ D C C C N S+ C C EG+VLA EDG +C+ E GP+
Sbjct: 604 RCRRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLA-EDGRRCKKCTE-----GPI--D 655
Query: 442 LCFNTQGSFHCG 453
L F GS G
Sbjct: 656 LVFVIDGSKSLG 667
Score = 88.2 bits (217), Expect = 2e-17
Identities = 46/115 (40%), Positives = 57/115 (49%), Gaps = 3/115 (2%)
Query: 354 CAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEE 413
CA C+N PG + C C GY + C+ D CA+ C Q C N GSF C C
Sbjct: 249 CAHFCINIPGSYVCRCKQGYILNS-DQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYS 307
Query: 414 GYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSCT 468
GY LA EDG +C VD C C+ C N GS+ C C G+ L P+ +CT
Sbjct: 308 GYALA-EDGKRCVAVDYCASENHG-CEHECVNADGSYLCQCHEGFALNPDKKTCT 360
Score = 62.0 bits (149), Expect = 2e-09
Identities = 31/79 (39%), Positives = 40/79 (50%), Gaps = 2/79 (2%)
Query: 389 CALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQG 448
C+ CA C N GS+ C C++GY+L D T C+ D C C+ LC N G
Sbjct: 242 CSTLEHNCAHFCINIPGSYVCRCKQGYIL-NSDQTTCRIQDLCAMEDHN-CEQLCVNVPG 299
Query: 449 SFHCGCLPGWVLAPNGVSC 467
SF C C G+ LA +G C
Sbjct: 300 SFVCQCYSGYALAEDGKRC 318
>gi|62548860 matrilin 2 isoform a precursor [Homo sapiens]
Length = 956
Score = 125 bits (314), Expect = 1e-28
Identities = 75/216 (34%), Positives = 106/216 (49%), Gaps = 11/216 (5%)
Query: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHG 323
C + GC Q C D SF+C C GF + +DL TC+ + C S +CV
Sbjct: 447 CAQQDHGCEQLCLNTED-SFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCV--NMD 503
Query: 324 KNYTCRCPQGYQLDSSQLDCVDVDECQ--DSPCAQECVNTPGGFRCECWVGYEPGGPGEG 381
+++ C+CP+G+ L S C +D C D C CV++ F C+C+ GY G+
Sbjct: 504 RSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGK- 562
Query: 382 ACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDS 441
C+ D C C C N+D S+ C C EG+ LA EDG +C+ D C C+
Sbjct: 563 TCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLA-EDGKRCRRKDVCKSTHHG-CEH 620
Query: 442 LCFNTQGSFHCGCLPGWVLAPNG---VSCTMGPVSL 474
+C N S+ C C G+VLA +G CT GP+ L
Sbjct: 621 ICVNNGNSYICKCSEGFVLAEDGRRCKKCTEGPIDL 656
Score = 121 bits (303), Expect = 2e-27
Identities = 63/190 (33%), Positives = 93/190 (48%), Gaps = 7/190 (3%)
Query: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQ 340
GS++C C+ G+ L D TC ++ C+ CV P ++ C+C GY L
Sbjct: 258 GSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVP--GSFVCQCYSGYALAEDG 315
Query: 341 LDCVDVDEC--QDSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQ 398
CV VD C ++ C ECVN G + C+C G+ P + C +D CA C
Sbjct: 316 KRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFAL-NPDKKTCTKIDYCASSNHGCQH 374
Query: 399 GCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGW 458
C NTD S+ C C +G+ L D C+ ++ C P C+ C N + S++C C G+
Sbjct: 375 ECVNTDDSYSCHCLKGFTL-NPDKKTCRRINYC-ALNKPGCEHECVNMEESYYCRCHRGY 432
Query: 459 VLAPNGVSCT 468
L PNG +C+
Sbjct: 433 TLDPNGKTCS 442
Score = 120 bits (302), Expect = 3e-27
Identities = 90/297 (30%), Positives = 117/297 (39%), Gaps = 89/297 (29%)
Query: 254 GPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSS---- 309
G CV+ Y C N GC +C DGS+LC C GF L D TC + C+SS
Sbjct: 315 GKRCVAVDY-CASENHGCEHECVNA-DGSYLCQCHEGFALNPDKKTCTKIDYCASSNHGC 372
Query: 310 --------------------------PCRGGATCVLGPHG---------KNYTCRCPQGY 334
CR C L G ++Y CRC +GY
Sbjct: 373 QHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGY 432
Query: 335 QLDSSQLDCVDVDEC--QDSPCAQECVNTPGGFRCECWVGYE------------------ 374
LD + C VD C QD C Q C+NT F C+C G+
Sbjct: 433 TLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSD 492
Query: 375 ------------------PGGP---GEG-ACQDVDECALGRSPCAQGCTNTDGSFHCSCE 412
P G +G C +D CALG C C +++ SF C C
Sbjct: 493 HGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCF 552
Query: 413 EGYVLAGEDGTQC--QDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
EGY+L EDG C +DV + + G C+ +C N+ S+ C CL G+ LA +G C
Sbjct: 553 EGYILR-EDGKTCRRKDVCQAIDHG---CEHICVNSDDSYTCECLEGFRLAEDGKRC 605
Score = 91.7 bits (226), Expect = 2e-18
Identities = 63/192 (32%), Positives = 82/192 (42%), Gaps = 14/192 (7%)
Query: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHG 323
C ++ GC C D SF C C G L D TCA + C+ +CV
Sbjct: 488 CLLSDHGCEYSCVNM-DRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSED- 545
Query: 324 KNYTCRCPQGYQLDSSQLDCVDVDECQ--DSPCAQECVNTPGGFRCECWVGYEPGGPGEG 381
++ C+C +GY L C D CQ D C CVN+ + CEC G+ G+
Sbjct: 546 -SFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGK- 603
Query: 382 ACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDS 441
C+ D C C C N S+ C C EG+VLA EDG +C+ E GP+
Sbjct: 604 RCRRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLA-EDGRRCKKCTE-----GPI--D 655
Query: 442 LCFNTQGSFHCG 453
L F GS G
Sbjct: 656 LVFVIDGSKSLG 667
Score = 88.2 bits (217), Expect = 2e-17
Identities = 46/115 (40%), Positives = 57/115 (49%), Gaps = 3/115 (2%)
Query: 354 CAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEE 413
CA C+N PG + C C GY + C+ D CA+ C Q C N GSF C C
Sbjct: 249 CAHFCINIPGSYVCRCKQGYILNS-DQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYS 307
Query: 414 GYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSCT 468
GY LA EDG +C VD C C+ C N GS+ C C G+ L P+ +CT
Sbjct: 308 GYALA-EDGKRCVAVDYCASENHG-CEHECVNADGSYLCQCHEGFALNPDKKTCT 360
Score = 62.0 bits (149), Expect = 2e-09
Identities = 31/79 (39%), Positives = 40/79 (50%), Gaps = 2/79 (2%)
Query: 389 CALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQG 448
C+ CA C N GS+ C C++GY+L D T C+ D C C+ LC N G
Sbjct: 242 CSTLEHNCAHFCINIPGSYVCRCKQGYIL-NSDQTTCRIQDLCAMEDHN-CEQLCVNVPG 299
Query: 449 SFHCGCLPGWVLAPNGVSC 467
SF C C G+ LA +G C
Sbjct: 300 SFVCQCYSGYALAEDGKRC 318
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 124 bits (311), Expect = 3e-28
Identities = 83/216 (38%), Positives = 104/216 (48%), Gaps = 24/216 (11%)
Query: 264 CNFNNGGCH--QDCFEGGDGSFLC--GCRPGFRLLDDLVTCASRNPCS-SSPCRGGATCV 318
C CH QDC + GS+ C C GFR D ++C N C SSPC
Sbjct: 5151 CALGRHTCHAGQDC-DNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQRCFNA 5209
Query: 319 LGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCA--QECVNTPGGFRCECWVGYEPG 376
+G ++ C C GYQL + C+DV+EC+ + C Q C NT GG++C + P
Sbjct: 5210 IG----SFHCGCEPGYQLKGRK--CMDVNECRQNVCRPDQHCKNTRGGYKC---IDLCPN 5260
Query: 377 GPGE---GACQDVDECALGRSPCA--QGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDEC 431
G + G C D+DEC G C Q C NT GS+ C C GY G G C D++EC
Sbjct: 5261 GMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGV-GRPCMDINEC 5319
Query: 432 VGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
P C C NT GSF C C PG L +G SC
Sbjct: 5320 EQVPKP-CAHQCSNTPGSFKCICPPGQHLLGDGKSC 5354
Score = 114 bits (285), Expect = 3e-25
Identities = 61/137 (44%), Positives = 72/137 (52%), Gaps = 9/137 (6%)
Query: 329 RCPQGYQLDSSQLDCVDVDEC-QDSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVD 387
+CP G+ LDS C D DEC +PC+ C N G + C C G G CQD+D
Sbjct: 5091 QCPSGFTLDSVGPFCADEDECAAGNPCSHSCHNAMGTYYCSCPKGLTIAADGR-TCQDID 5149
Query: 388 ECALGRSPC--AQGCTNTDGSFHC--SCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLC 443
ECALGR C Q C NT GS+ C C G+ DG CQD++EC C C
Sbjct: 5150 ECALGRHTCHAGQDCDNTIGSYRCVVRCGSGF-RRTSDGLSCQDINEC--QESSPCHQRC 5206
Query: 444 FNTQGSFHCGCLPGWVL 460
FN GSFHCGC PG+ L
Sbjct: 5207 FNAIGSFHCGCEPGYQL 5223
Score = 108 bits (271), Expect = 1e-23
Identities = 64/163 (39%), Positives = 77/163 (47%), Gaps = 10/163 (6%)
Query: 271 CHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRC 330
CHQ CF GSF CGC PG++L C N C + CR C G C
Sbjct: 5202 CHQRCFNA-IGSFHCGCEPGYQLKGR--KCMDVNECRQNVCRPDQHCKNTRGGYKCIDLC 5258
Query: 331 PQGYQLDSSQLDCVDVDECQDSP--CA--QECVNTPGGFRCECWVGYEPGGPGEGACQDV 386
P G + C+D+DEC+D C Q C NT G +RC C GY G G C D+
Sbjct: 5259 PNG-MTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGR-PCMDI 5316
Query: 387 DECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVD 429
+EC PCA C+NT GSF C C G L G DG C ++
Sbjct: 5317 NECEQVPKPCAHQCSNTPGSFKCICPPGQHLLG-DGKSCAGLE 5358
Score = 104 bits (259), Expect = 3e-22
Identities = 69/189 (36%), Positives = 89/189 (47%), Gaps = 23/189 (12%)
Query: 287 CRPGFRLLDDLVTCASRNPCSS-SPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVD 345
C GF L CA + C++ +PC +G Y C CP+G + + C D
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNPCSHSCHNAMG----TYYCSCPKGLTIAADGRTCQD 5147
Query: 346 VDEC----QDSPCAQECVNTPGGFRC--ECWVGYEPGGPGEGACQDVDECALGRSPCAQG 399
+DEC Q+C NT G +RC C G+ G +CQD++EC SPC Q
Sbjct: 5148 IDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGL-SCQDINECQES-SPCHQR 5205
Query: 400 CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLC--DSLCFNTQGSFHC--GCL 455
C N GSFHC CE GY L G +C DV+EC +C D C NT+G + C C
Sbjct: 5206 CFNAIGSFHCGCEPGYQLKGR---KCMDVNEC---RQNVCRPDQHCKNTRGGYKCIDLCP 5259
Query: 456 PGWVLAPNG 464
G A NG
Sbjct: 5260 NGMTKAENG 5268
Score = 74.3 bits (181), Expect = 3e-13
Identities = 68/223 (30%), Positives = 87/223 (39%), Gaps = 33/223 (14%)
Query: 271 CHQDCFEGGDGSFLCGCRPGFRLLDDLVTCAS--RNPCSSSPCRGGATCVLGPHGKNYTC 328
C C GSF C C PG LL D +CA R P + P NY
Sbjct: 5326 CAHQC-SNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQ- 5383
Query: 329 RCPQGYQLDSSQLDCVDVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDE 388
PQ + S L E ++S + T R C G E C D+DE
Sbjct: 5384 --PQQHYRQYSHLYS-SYSEYRNSRTSLS--RTRRTIRKTCPEGSEAS---HDTCVDIDE 5435
Query: 389 CALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPG---GPLCDSLCFN 445
C C C NT GS+ C C GY L +G CQD+DEC+ GP + +CFN
Sbjct: 5436 CE-NTDACQHECKNTFGSYQCICPPGYQLT-HNGKTCQDIDECLEQNVHCGP--NRMCFN 5491
Query: 446 TQGSFHC---GCLPGWV-----------LAPNGVSCTMGPVSL 474
+GS+ C C P + PN + C + P +L
Sbjct: 5492 MRGSYQCIDTPCPPNYQRDPVSGFCLKNCPPNDLECALSPYAL 5534
Score = 42.0 bits (97), Expect = 0.002
Identities = 21/57 (36%), Positives = 28/57 (49%), Gaps = 3/57 (5%)
Query: 411 CEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSC 467
C G+ L G C D DEC G P C C N G+++C C G +A +G +C
Sbjct: 5092 CPSGFTLDSV-GPFCADEDECAA-GNP-CSHSCHNAMGTYYCSCPKGLTIAADGRTC 5145
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.135 0.436
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,725,603
Number of Sequences: 37866
Number of extensions: 2030930
Number of successful extensions: 17332
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 211
Number of HSP's successfully gapped in prelim test: 606
Number of HSP's that attempted gapping in prelim test: 9654
Number of HSP's gapped (non-prelim): 4822
length of query: 652
length of database: 18,247,518
effective HSP length: 109
effective length of query: 543
effective length of database: 14,120,124
effective search space: 7667227332
effective search space used: 7667227332
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.