BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|8659574 transcription factor E3 [Homo sapiens] (575 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|8659574 transcription factor E3 [Homo sapiens] 1115 0.0 gi|38156699 microphthalmia-associated transcription factor isofo... 448 e-126 gi|38156703 microphthalmia-associated transcription factor isofo... 434 e-121 gi|38156701 microphthalmia-associated transcription factor isofo... 433 e-121 gi|38156705 microphthalmia-associated transcription factor isofo... 432 e-121 gi|38156697 microphthalmia-associated transcription factor isofo... 371 e-103 gi|4557755 microphthalmia-associated transcription factor isofor... 365 e-101 gi|24307933 transcription factor EB [Homo sapiens] 345 8e-95 gi|6912702 transcription factor EC isoform a [Homo sapiens] 257 2e-68 gi|64762402 transcription factor EC isoform b [Homo sapiens] 234 2e-61 gi|52630419 sterol regulatory element binding transcription fact... 61 3e-09 gi|22547195 sterol regulatory element binding transcription fact... 61 3e-09 gi|4507847 upstream stimulatory factor 2 isoform 1 [Homo sapiens] 57 5e-08 gi|27477113 sterol regulatory element-binding transcription fact... 56 1e-07 gi|46877105 upstream stimulatory factor 2 isoform 2 [Homo sapiens] 56 1e-07 gi|19923312 v-myc myelocytomatosis viral related oncogene, neuro... 53 9e-07 gi|6005934 upstream stimulatory factor 1 isoform 1 [Homo sapiens] 53 9e-07 gi|46877102 upstream stimulatory factor 1 isoform 2 [Homo sapiens] 53 9e-07 gi|14602433 Williams Beuren syndrome chromosome region 14 isofor... 50 4e-06 gi|91208420 bassoon protein [Homo sapiens] 50 7e-06 gi|114431248 hypothetical protein LOC205717 [Homo sapiens] 49 2e-05 gi|47717116 MAX interactor 1 isoform b [Homo sapiens] 48 3e-05 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 47 5e-05 gi|9945318 MAX binding protein [Homo sapiens] 47 5e-05 gi|4758010 clock [Homo sapiens] 46 1e-04 gi|30795240 aryl hydrocarbon receptor nuclear translocator isofo... 45 1e-04 gi|4502231 aryl hydrocarbon receptor nuclear translocator isofor... 45 1e-04 gi|5453734 MAD4 [Homo sapiens] 44 3e-04 gi|146134388 YLP motif containing 1 [Homo sapiens] 44 5e-04 gi|56549694 enabled homolog isoform a [Homo sapiens] 43 7e-04 >gi|8659574 transcription factor E3 [Homo sapiens] Length = 575 Score = 1115 bits (2885), Expect = 0.0 Identities = 575/575 (100%), Positives = 575/575 (100%) Query: 1 MSHAAEPARDGVEASAEGPRAVFVLLEERRPADSAQLLSLNSLLPESGIVADIELENVLD 60 MSHAAEPARDGVEASAEGPRAVFVLLEERRPADSAQLLSLNSLLPESGIVADIELENVLD Sbjct: 1 MSHAAEPARDGVEASAEGPRAVFVLLEERRPADSAQLLSLNSLLPESGIVADIELENVLD 60 Query: 61 PDSFYELKSQPLPLRSSLPISLQATPATPATLSASSSAGGSRTPAMSSSSSSRVLLRQQL 120 PDSFYELKSQPLPLRSSLPISLQATPATPATLSASSSAGGSRTPAMSSSSSSRVLLRQQL Sbjct: 61 PDSFYELKSQPLPLRSSLPISLQATPATPATLSASSSAGGSRTPAMSSSSSSRVLLRQQL 120 Query: 121 MRAQAQEQERRERREQAAAAPFPSPAPASPAISVVGVSAGGHTLSRPPPAQVPREVLKVQ 180 MRAQAQEQERRERREQAAAAPFPSPAPASPAISVVGVSAGGHTLSRPPPAQVPREVLKVQ Sbjct: 121 MRAQAQEQERRERREQAAAAPFPSPAPASPAISVVGVSAGGHTLSRPPPAQVPREVLKVQ 180 Query: 181 THLENPTRYHLQQARRQQVKQYLSTTLGPKLASQALTPPPGPASAQPLPAPEAAHTTGPT 240 THLENPTRYHLQQARRQQVKQYLSTTLGPKLASQALTPPPGPASAQPLPAPEAAHTTGPT Sbjct: 181 THLENPTRYHLQQARRQQVKQYLSTTLGPKLASQALTPPPGPASAQPLPAPEAAHTTGPT 240 Query: 241 GSAPNSPMALLTIGSSSEKEIDDVIDEIISLESSYNDEMLSYLPGGTTGLQLPSTLPVSG 300 GSAPNSPMALLTIGSSSEKEIDDVIDEIISLESSYNDEMLSYLPGGTTGLQLPSTLPVSG Sbjct: 241 GSAPNSPMALLTIGSSSEKEIDDVIDEIISLESSYNDEMLSYLPGGTTGLQLPSTLPVSG 300 Query: 301 NLLDVYSSQGVATPAITVSNSCPAELPNIKREISETEAKALLKERQKKDNHNLIERRRRF 360 NLLDVYSSQGVATPAITVSNSCPAELPNIKREISETEAKALLKERQKKDNHNLIERRRRF Sbjct: 301 NLLDVYSSQGVATPAITVSNSCPAELPNIKREISETEAKALLKERQKKDNHNLIERRRRF 360 Query: 361 NINDRIKELGTLIPKSSDPEMRWNKGTILKASVDYIRKLQKEQQRSKDLESRQRSLEQAN 420 NINDRIKELGTLIPKSSDPEMRWNKGTILKASVDYIRKLQKEQQRSKDLESRQRSLEQAN Sbjct: 361 NINDRIKELGTLIPKSSDPEMRWNKGTILKASVDYIRKLQKEQQRSKDLESRQRSLEQAN 420 Query: 421 RSLQLRIQELELQAQIHGLPVPPTPGLLSLATTSASDSLKPEQLDIEEEGRPGAATFHVG 480 RSLQLRIQELELQAQIHGLPVPPTPGLLSLATTSASDSLKPEQLDIEEEGRPGAATFHVG Sbjct: 421 RSLQLRIQELELQAQIHGLPVPPTPGLLSLATTSASDSLKPEQLDIEEEGRPGAATFHVG 480 Query: 481 GGPAQNAPHQQPPAPPSDALLDLHFPSDHLGDLGDPFHLGLEDILMEEEEGVVGGLSGGA 540 GGPAQNAPHQQPPAPPSDALLDLHFPSDHLGDLGDPFHLGLEDILMEEEEGVVGGLSGGA Sbjct: 481 GGPAQNAPHQQPPAPPSDALLDLHFPSDHLGDLGDPFHLGLEDILMEEEEGVVGGLSGGA 540 Query: 541 LSPLRAASDPLLSSVSPAVSKASSRRSSFSMEEES 575 LSPLRAASDPLLSSVSPAVSKASSRRSSFSMEEES Sbjct: 541 LSPLRAASDPLLSSVSPAVSKASSRRSSFSMEEES 575 >gi|38156699 microphthalmia-associated transcription factor isoform 1 [Homo sapiens] Length = 520 Score = 448 bits (1153), Expect = e-126 Identities = 285/582 (48%), Positives = 347/582 (59%), Gaps = 124/582 (21%) Query: 46 ESGIVADIELENVL--DPDSFYELKSQPLPLRSSLPISLQATPATPATLSASSSAGGSRT 103 ESGIV D E+ +P ++YELKSQPL SS + G S+ Sbjct: 4 ESGIVPDFEVGEEFHEEPKTYYELKSQPLKSSSS-----------------AEHPGASKP 46 Query: 104 PAMSSSSSSRVLLRQQLMRAQAQEQERRERREQAAAAPFPS---PAPASPAISVVGVSAG 160 P SSS +SR+LLRQQLMR Q QEQERRE++++ AA F P +PAI+V Sbjct: 47 PISSSSMTSRILLRQQLMREQMQEQERREQQQKLQAAQFMQQRVPVSQTPAINV------ 100 Query: 161 GHTLSRPPPAQVPREVLKVQTHLENPTRYHLQQARRQQVKQYLSTTLGPKLASQALTPP- 219 + P QVP EVLKVQTHLENPT+YH+QQA+RQQVKQYLSTTL K A+Q L+ P Sbjct: 101 SVPTTLPSATQVPMEVLKVQTHLENPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSLPC 160 Query: 220 ---PGPASAQPLPAPEAAHTTGPTGSAPNSPMALLTIGSSSEKE---------------- 260 PG P+P SAPNSPMA+LT+ S+ EKE Sbjct: 161 PNQPGDHVMPPVPG----------SSAPNSPMAMLTLNSNCEKEGFYKFEEQNRAESECP 210 Query: 261 ------------IDDVIDEIISLESSYNDEMLSYLPGGTTGLQLPSTLPVSGNLLDVYSS 308 +DDVID+IISLESSYN+E+L + LQ+ +TLPVSGNL+D+Y + Sbjct: 211 GMNTHSRASCMQMDDVIDDIISLESSYNEEILGLMD---PALQMANTLPVSGNLIDLYGN 267 Query: 309 QGVATPAITVSNSCPAELPNIKREISETEAKALLKERQKKDNHNLIERRRRFNINDRIKE 368 QG+ P +T+SNSCPA LPNIKRE++E+EA+AL KERQKKDNHNLIERRRRFNINDRIKE Sbjct: 268 QGLPPPGLTISNSCPANLPNIKRELTESEARALAKERQKKDNHNLIERRRRFNINDRIKE 327 Query: 369 LGTLIPKSSDPEMRWNKGTILKASVDYIRKLQKEQQRSKDLESRQRSLEQANRSLQLRIQ 428 LGTLIPKS+DP+MRWNKGTILKASVDYIRKLQ+EQQR+K+LE+RQ+ LE ANR L LRIQ Sbjct: 328 LGTLIPKSNDPDMRWNKGTILKASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQ 387 Query: 429 ELELQAQIHGLPVPPTPGLLS-----------LATTSASDSLKPEQLDI----EEEGRPG 473 ELE+QA+ HGL + P+ GL S + S L D+ + G Sbjct: 388 ELEMQARAHGLSLIPSTGLCSPDLVNRIIKQEPVLENCSQDLLQHHADLTCTTTLDLTDG 447 Query: 474 AATF--HVGGGPAQNAPHQQPPAPPSDALLDLHFPSDHLGDLGDPFHLGLEDILMEEEEG 531 TF ++G G N + P S LEDILM++ Sbjct: 448 TITFNNNLGTGTEANQAYSVPTKMGSK----------------------LEDILMDD--- 482 Query: 532 VVGGLSGGALSPLRAASDPLLSSVSPAVSKASSRRSSFSMEE 573 LSP+ +DPLLSSVSP SK SSRRSS SMEE Sbjct: 483 --------TLSPV-GVTDPLLSSVSPGASKTSSRRSSMSMEE 515 >gi|38156703 microphthalmia-associated transcription factor isoform 2 [Homo sapiens] Length = 504 Score = 434 bits (1116), Expect = e-121 Identities = 269/534 (50%), Positives = 328/534 (61%), Gaps = 105/534 (19%) Query: 92 LSASSSAGGSRTPAMSSSSSSRVLLRQQLMRAQAQEQERRERREQAAAAPFPS---PAPA 148 LS++ G S+ P SSS +SR+LLRQQLMR Q QEQERRE++++ AA F P Sbjct: 19 LSSAEHPGASKPPISSSSMTSRILLRQQLMREQMQEQERREQQQKLQAAQFMQQRVPVSQ 78 Query: 149 SPAISVVGVSAGGHTLSRPPPAQVPREVLKVQTHLENPTRYHLQQARRQQVKQYLSTTLG 208 +PAI+V + P QVP EVLKVQTHLENPT+YH+QQA+RQQVKQYLSTTL Sbjct: 79 TPAINV------SVPTTLPSATQVPMEVLKVQTHLENPTKYHIQQAQRQQVKQYLSTTLA 132 Query: 209 PKLASQALTPP----PGPASAQPLPAPEAAHTTGPTGSAPNSPMALLTIGSSSEKE---- 260 K A+Q L+ P PG P+P SAPNSPMA+LT+ S+ EKE Sbjct: 133 NKHANQVLSLPCPNQPGDHVMPPVPG----------SSAPNSPMAMLTLNSNCEKEGFYK 182 Query: 261 ------------------------IDDVIDEIISLESSYNDEMLSYLPGGTTGLQLPSTL 296 +DDVID+IISLESSYN+E+L + LQ+ +TL Sbjct: 183 FEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSYNEEILGLMD---PALQMANTL 239 Query: 297 PVSGNLLDVYSSQGVATPAITVSNSCPAELPNIKREISETEAKALLKERQKKDNHNLIER 356 PVSGNL+D+Y +QG+ P +T+SNSCPA LPNIKRE++E+EA+AL KERQKKDNHNLIER Sbjct: 240 PVSGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELTESEARALAKERQKKDNHNLIER 299 Query: 357 RRRFNINDRIKELGTLIPKSSDPEMRWNKGTILKASVDYIRKLQKEQQRSKDLESRQRSL 416 RRRFNINDRIKELGTLIPKS+DP+MRWNKGTILKASVDYIRKLQ+EQQR+K+LE+RQ+ L Sbjct: 300 RRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDYIRKLQREQQRAKELENRQKKL 359 Query: 417 EQANRSLQLRIQELELQAQIHGLPVPPTPGLLS-----------LATTSASDSLKPEQLD 465 E ANR L LRIQELE+QA+ HGL + P+ GL S + S L D Sbjct: 360 EHANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNRIIKQEPVLENCSQDLLQHHAD 419 Query: 466 I----EEEGRPGAATF--HVGGGPAQNAPHQQPPAPPSDALLDLHFPSDHLGDLGDPFHL 519 + + G TF ++G G N + P S Sbjct: 420 LTCTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSK--------------------- 458 Query: 520 GLEDILMEEEEGVVGGLSGGALSPLRAASDPLLSSVSPAVSKASSRRSSFSMEE 573 LEDILM++ LSP+ +DPLLSSVSP SK SSRRSS SMEE Sbjct: 459 -LEDILMDD-----------TLSPV-GVTDPLLSSVSPGASKTSSRRSSMSMEE 499 >gi|38156701 microphthalmia-associated transcription factor isoform 3 [Homo sapiens] Length = 519 Score = 433 bits (1114), Expect = e-121 Identities = 273/541 (50%), Positives = 330/541 (60%), Gaps = 108/541 (19%) Query: 88 TPATLSASSSA---GGSRTPAMSSSSSSRVLLRQQLMRAQAQEQERRERREQAAAAPFPS 144 T S SSSA G S+ P SSS +SR+LLRQQLMR Q QEQERRE++++ AA F Sbjct: 27 TLCLFSRSSSAEHPGASKPPISSSSMTSRILLRQQLMREQMQEQERREQQQKLQAAQFMQ 86 Query: 145 ---PAPASPAISVVGVSAGGHTLSRPPPAQVPREVLKVQTHLENPTRYHLQQARRQQVKQ 201 P +PAI+V + P QVP EVLKVQTHLENPT+YH+QQA+RQQVKQ Sbjct: 87 QRVPVSQTPAINV------SVPTTLPSATQVPMEVLKVQTHLENPTKYHIQQAQRQQVKQ 140 Query: 202 YLSTTLGPKLASQALTPP----PGPASAQPLPAPEAAHTTGPTGSAPNSPMALLTIGSSS 257 YLSTTL K A+Q L+ P PG P+P SAPNSPMA+LT+ S+ Sbjct: 141 YLSTTLANKHANQVLSLPCPNQPGDHVMPPVPG----------SSAPNSPMAMLTLNSNC 190 Query: 258 EKE----------------------------IDDVIDEIISLESSYNDEMLSYLPGGTTG 289 EKE +DDVID+IISLESSYN+E+L + Sbjct: 191 EKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSYNEEILGLMD---PA 247 Query: 290 LQLPSTLPVSGNLLDVYSSQGVATPAITVSNSCPAELPNIKREISETEAKALLKERQKKD 349 LQ+ +TLPVSGNL+D+Y +QG+ P +T+SNSCPA LPNIKRE++E+EA+AL KERQKKD Sbjct: 248 LQMANTLPVSGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELTESEARALAKERQKKD 307 Query: 350 NHNLIERRRRFNINDRIKELGTLIPKSSDPEMRWNKGTILKASVDYIRKLQKEQQRSKDL 409 NHNLIERRRRFNINDRIKELGTLIPKS+DP+MRWNKGTILKASVDYIRKLQ+EQQR+K+L Sbjct: 308 NHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDYIRKLQREQQRAKEL 367 Query: 410 ESRQRSLEQANRSLQLRIQELELQAQIHGLPVPPTPGLLS-----------LATTSASDS 458 E+RQ+ LE ANR L LRIQELE+QA+ HGL + P+ GL S + S Sbjct: 368 ENRQKKLEHANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNRIIKQEPVLENCSQD 427 Query: 459 LKPEQLDI----EEEGRPGAATF--HVGGGPAQNAPHQQPPAPPSDALLDLHFPSDHLGD 512 L D+ + G TF ++G G N + P S Sbjct: 428 LLQHHADLTCTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSK-------------- 473 Query: 513 LGDPFHLGLEDILMEEEEGVVGGLSGGALSPLRAASDPLLSSVSPAVSKASSRRSSFSME 572 LEDILM++ LSP+ +DPLLSSVSP SK SSRRSS SME Sbjct: 474 --------LEDILMDD-----------TLSPV-GVTDPLLSSVSPGASKTSSRRSSMSME 513 Query: 573 E 573 E Sbjct: 514 E 514 >gi|38156705 microphthalmia-associated transcription factor isoform 6 [Homo sapiens] Length = 495 Score = 432 bits (1112), Expect = e-121 Identities = 268/533 (50%), Positives = 327/533 (61%), Gaps = 105/533 (19%) Query: 93 SASSSAGGSRTPAMSSSSSSRVLLRQQLMRAQAQEQERRERREQAAAAPFPS---PAPAS 149 S++ G S+ P SSS +SR+LLRQQLMR Q QEQERRE++++ AA F P + Sbjct: 11 SSAEHPGASKPPISSSSMTSRILLRQQLMREQMQEQERREQQQKLQAAQFMQQRVPVSQT 70 Query: 150 PAISVVGVSAGGHTLSRPPPAQVPREVLKVQTHLENPTRYHLQQARRQQVKQYLSTTLGP 209 PAI+V + P QVP EVLKVQTHLENPT+YH+QQA+RQQVKQYLSTTL Sbjct: 71 PAINV------SVPTTLPSATQVPMEVLKVQTHLENPTKYHIQQAQRQQVKQYLSTTLAN 124 Query: 210 KLASQALTPP----PGPASAQPLPAPEAAHTTGPTGSAPNSPMALLTIGSSSEKE----- 260 K A+Q L+ P PG P+P SAPNSPMA+LT+ S+ EKE Sbjct: 125 KHANQVLSLPCPNQPGDHVMPPVPG----------SSAPNSPMAMLTLNSNCEKEGFYKF 174 Query: 261 -----------------------IDDVIDEIISLESSYNDEMLSYLPGGTTGLQLPSTLP 297 +DDVID+IISLESSYN+E+L + LQ+ +TLP Sbjct: 175 EEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSYNEEILGLMD---PALQMANTLP 231 Query: 298 VSGNLLDVYSSQGVATPAITVSNSCPAELPNIKREISETEAKALLKERQKKDNHNLIERR 357 VSGNL+D+Y +QG+ P +T+SNSCPA LPNIKRE++E+EA+AL KERQKKDNHNLIERR Sbjct: 232 VSGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELTESEARALAKERQKKDNHNLIERR 291 Query: 358 RRFNINDRIKELGTLIPKSSDPEMRWNKGTILKASVDYIRKLQKEQQRSKDLESRQRSLE 417 RRFNINDRIKELGTLIPKS+DP+MRWNKGTILKASVDYIRKLQ+EQQR+K+LE+RQ+ LE Sbjct: 292 RRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDYIRKLQREQQRAKELENRQKKLE 351 Query: 418 QANRSLQLRIQELELQAQIHGLPVPPTPGLLS-----------LATTSASDSLKPEQLDI 466 ANR L LRIQELE+QA+ HGL + P+ GL S + S L D+ Sbjct: 352 HANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNRIIKQEPVLENCSQDLLQHHADL 411 Query: 467 ----EEEGRPGAATF--HVGGGPAQNAPHQQPPAPPSDALLDLHFPSDHLGDLGDPFHLG 520 + G TF ++G G N + P S Sbjct: 412 TCTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSK---------------------- 449 Query: 521 LEDILMEEEEGVVGGLSGGALSPLRAASDPLLSSVSPAVSKASSRRSSFSMEE 573 LEDILM++ LSP+ +DPLLSSVSP SK SSRRSS SMEE Sbjct: 450 LEDILMDD-----------TLSPV-GVTDPLLSSVSPGASKTSSRRSSMSMEE 490 >gi|38156697 microphthalmia-associated transcription factor isoform 5 [Homo sapiens] Length = 413 Score = 371 bits (953), Expect = e-103 Identities = 227/445 (51%), Positives = 275/445 (61%), Gaps = 96/445 (21%) Query: 178 KVQTHLENPTRYHLQQARRQQVKQYLSTTLGPKLASQALTPP----PGPASAQPLPAPEA 233 +VQTHLENPT+YH+QQA+RQQVKQYLSTTL K A+Q L+ P PG P+P Sbjct: 11 QVQTHLENPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSLPCPNQPGDHVMPPVPG--- 67 Query: 234 AHTTGPTGSAPNSPMALLTIGSSSEKE----------------------------IDDVI 265 SAPNSPMA+LT+ S+ EKE +DDVI Sbjct: 68 -------SSAPNSPMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVI 120 Query: 266 DEIISLESSYNDEMLSYLPGGTTGLQLPSTLPVSGNLLDVYSSQGVATPAITVSNSCPAE 325 D+IISLESSYN+E+L + LQ+ +TLPVSGNL+D+Y +QG+ P +T+SNSCPA Sbjct: 121 DDIISLESSYNEEILGLMD---PALQMANTLPVSGNLIDLYGNQGLPPPGLTISNSCPAN 177 Query: 326 LPNIKREISETEAKALLKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSSDPEMRWNK 385 LPNIKRE++E+EA+AL KERQKKDNHNLIERRRRFNINDRIKELGTLIPKS+DP+MRWNK Sbjct: 178 LPNIKRELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNK 237 Query: 386 GTILKASVDYIRKLQKEQQRSKDLESRQRSLEQANRSLQLRIQELELQAQIHGLPVPPTP 445 GTILKASVDYIRKLQ+EQQR+K+LE+RQ+ LE ANR L LRIQELE+QA+ HGL + P+ Sbjct: 238 GTILKASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGLSLIPST 297 Query: 446 GLLS-----------LATTSASDSLKPEQLDI----EEEGRPGAATF--HVGGGPAQNAP 488 GL S + S L D+ + G TF ++G G N Sbjct: 298 GLCSPDLVNRIIKQEPVLENCSQDLLQHHADLTCTTTLDLTDGTITFNNNLGTGTEANQA 357 Query: 489 HQQPPAPPSDALLDLHFPSDHLGDLGDPFHLGLEDILMEEEEGVVGGLSGGALSPLRAAS 548 + P S LEDILM++ LSP+ + Sbjct: 358 YSVPTKMGSK----------------------LEDILMDD-----------TLSPV-GVT 383 Query: 549 DPLLSSVSPAVSKASSRRSSFSMEE 573 DPLLSSVSP SK SSRRSS SMEE Sbjct: 384 DPLLSSVSPGASKTSSRRSSMSMEE 408 >gi|4557755 microphthalmia-associated transcription factor isoform 4 [Homo sapiens] Length = 419 Score = 365 bits (936), Expect = e-101 Identities = 227/451 (50%), Positives = 275/451 (60%), Gaps = 102/451 (22%) Query: 178 KVQTHLENPTRYHLQQARRQQVKQYLSTTLGPKLASQALTPP----PGPASAQPLPAPEA 233 +VQTHLENPT+YH+QQA+RQQVKQYLSTTL K A+Q L+ P PG P+P Sbjct: 11 QVQTHLENPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSLPCPNQPGDHVMPPVPG--- 67 Query: 234 AHTTGPTGSAPNSPMALLTIGSSSEKE----------------------------IDDVI 265 SAPNSPMA+LT+ S+ EKE +DDVI Sbjct: 68 -------SSAPNSPMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVI 120 Query: 266 DEIISLESSYNDEMLSYLPGGTTGLQLPSTLPVSGNLLDVYSSQGVATPAITVSNSCPAE 325 D+IISLESSYN+E+L + LQ+ +TLPVSGNL+D+Y +QG+ P +T+SNSCPA Sbjct: 121 DDIISLESSYNEEILGLMD---PALQMANTLPVSGNLIDLYGNQGLPPPGLTISNSCPAN 177 Query: 326 LPNIKREIS------ETEAKALLKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSSDP 379 LPNIKRE++ E+EA+AL KERQKKDNHNLIERRRRFNINDRIKELGTLIPKS+DP Sbjct: 178 LPNIKRELTACIFPTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDP 237 Query: 380 EMRWNKGTILKASVDYIRKLQKEQQRSKDLESRQRSLEQANRSLQLRIQELELQAQIHGL 439 +MRWNKGTILKASVDYIRKLQ+EQQR+K+LE+RQ+ LE ANR L LRIQELE+QA+ HGL Sbjct: 238 DMRWNKGTILKASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGL 297 Query: 440 PVPPTPGLLS-----------LATTSASDSLKPEQLDI----EEEGRPGAATF--HVGGG 482 + P+ GL S + S L D+ + G TF ++G G Sbjct: 298 SLIPSTGLCSPDLVNRIIKQEPVLENCSQDLLQHHADLTCTTTLDLTDGTITFNNNLGTG 357 Query: 483 PAQNAPHQQPPAPPSDALLDLHFPSDHLGDLGDPFHLGLEDILMEEEEGVVGGLSGGALS 542 N + P S LEDILM++ LS Sbjct: 358 TEANQAYSVPTKMGSK----------------------LEDILMDD-----------TLS 384 Query: 543 PLRAASDPLLSSVSPAVSKASSRRSSFSMEE 573 P+ +DPLLSSVSP SK SSRRSS SMEE Sbjct: 385 PV-GVTDPLLSSVSPGASKTSSRRSSMSMEE 414 >gi|24307933 transcription factor EB [Homo sapiens] Length = 476 Score = 345 bits (884), Expect = 8e-95 Identities = 226/499 (45%), Positives = 294/499 (58%), Gaps = 64/499 (12%) Query: 111 SSRVLLRQQLMRAQAQEQERRERREQAAAAPFPSP----------APASPAISVVGVSAG 160 +SR+ LR QLMR QAQ++E+RER +Q A + P +PAI+ Sbjct: 2 ASRIGLRMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQLGGPPTPAINTPV---- 57 Query: 161 GHTLSRPPPAQVPREVLKVQTHLENPTRYHLQQARRQQVKQYLSTTLGPKLASQAL---- 216 H S PP VP EVLKVQ++LENPT YHLQQ++ Q+V++YLS T G K A+ Sbjct: 58 -HFQSPPP---VPGEVLKVQSYLENPTSYHLQQSQHQKVREYLSETYGNKFAAHISPAQG 113 Query: 217 TPPPGPASAQPLPAPEAAHTTGPTG--SAPNSPMALLTIGSSSEKEIDDVIDEIISLESS 274 +P P PA++ P A H + SAPNSPMA+L IGS+ E+E+DDVID I+ L Sbjct: 114 SPKPPPAAS---PGVRAGHVLSSSAGNSAPNSPMAMLHIGSNPERELDDVIDNIMRL--- 167 Query: 275 YNDEMLSYLPGGTTGLQLPSTLPVSGNLLDVYSSQGVATPAIT--VSNSCPAELPNIKRE 332 D++L Y+ +Q+P+TLP+S + L+VYSS T ++ S+SCPA+L KRE Sbjct: 168 --DDVLGYI---NPEMQMPNTLPLSSSHLNVYSSDPQVTASLVGVTSSSCPADLTQ-KRE 221 Query: 333 ISETEAKALLKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSSDPEMRWNKGTILKAS 392 +++ E++AL KERQKKDNHNLIERRRRFNINDRIKELG LIPK++D ++RWNKGTILKAS Sbjct: 222 LTDAESRALAKERQKKDNHNLIERRRRFNINDRIKELGMLIPKANDLDVRWNKGTILKAS 281 Query: 393 VDYIRKLQKEQQRSKDLESRQRSLEQANRSLQLRIQELELQAQIHGLPVPPTPGLLSLAT 452 VDYIR++QK+ Q+S++LE+ R LE N+ L LRIQELE+QA++HGLP G+ Sbjct: 282 VDYIRRMQKDLQKSRELENHSRRLEMTNKQLWLRIQELEMQARVHGLPTTSPSGM----- 336 Query: 453 TSASDSLKPEQLDIEEEGRPGAATFHVGGGPAQNAPHQQPPAPPSDALLDLHFPSDHLGD 512 A + + + ++ E PG A P PP P P HL Sbjct: 337 NMAELAQQVVKQELPSEEGPGEALMLGAEVPDPEPLPALPPQAPLPLPTQPPSPFHHLDF 396 Query: 513 LGDPFHLGLEDILMEEEEGVVGGLSGGALSP------------------LRAASDPLLSS 554 G ED E G L+ G SP L ASDPLLS+ Sbjct: 397 SHSLSFGGRED---EGPPGYPEPLAPGHGSPFPSLSKKDLDLMLLDDSLLPLASDPLLST 453 Query: 555 VSPAVSKASSRRSSFSMEE 573 +SP SKASSRRSSFSMEE Sbjct: 454 MSPEASKASSRRSSFSMEE 472 >gi|6912702 transcription factor EC isoform a [Homo sapiens] Length = 347 Score = 257 bits (657), Expect = 2e-68 Identities = 166/360 (46%), Positives = 213/360 (59%), Gaps = 41/360 (11%) Query: 222 PASAQPLPAPEAAHTT--GPTGSAPNSPMALLTIGSSSEK---EIDDVIDEIISLESSYN 276 PA P + AHTT G N LL IG + ++DVI++II +ESS+ Sbjct: 17 PAVPSGGPLVQHAHTTLDSDAGLTENPLTKLLAIGKEDDNAQWHMEDVIEDIIGMESSFK 76 Query: 277 DEMLSYLPGGTTGLQLPSTLPVSGNLLDVYSSQGVATPAIT--VSNSCPAELPNIKREIS 334 +E G + L + TL SG++LDVYS + +P S SCP+ LP +KREI+ Sbjct: 77 EE------GADSPLLMQRTL--SGSILDVYSGEQGISPINMGLTSASCPSSLP-MKREIT 127 Query: 335 ETEAKALLKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSSDPEMRWNKGTILKASVD 394 ET+ +AL KERQKKDNHNLIERRRR+NIN RIKELGTLIPKS+DP+MRWNKGTILKASV+ Sbjct: 128 ETDTRALAKERQKKDNHNLIERRRRYNINYRIKELGTLIPKSNDPDMRWNKGTILKASVE 187 Query: 395 YIRKLQKEQQRSKDLESRQRSLEQANRSLQLRIQELELQAQIHGLPVPPTPGLLSLATTS 454 YI+ LQKEQQR+++LE RQ+ LEQANR L LRIQELE+QA+ HGLP + G + L Sbjct: 188 YIKWLQKEQQRARELEHRQKKLEQANRRLLLRIQELEIQARTHGLPTLASLGTVDLGAHV 247 Query: 455 ASDSLKPEQLDIEEEGRPGAATFHVGGGPAQNAPHQQPPAPP-SDALLDLHFPSDHLGDL 513 PEQ ++ Q Q P+P D + P + DL Sbjct: 248 TKQQSHPEQNSVDY---------------CQQLTVSQGPSPELCDQAIAFSDPLSYFTDL 292 Query: 514 GDPFHLGLEDILMEEEEGVVGGLSGGALSPLRAASDPLLSSVSPAVSKASSRRSSFSMEE 573 ++EE+ + G L +SP +DPLLS+ SPAVSK SSRRSSFS ++ Sbjct: 293 S-------FSAALKEEQRLDGMLLDDTISPF--GTDPLLSATSPAVSKESSRRSSFSSDD 343 >gi|64762402 transcription factor EC isoform b [Homo sapiens] Length = 318 Score = 234 bits (596), Expect = 2e-61 Identities = 140/279 (50%), Positives = 177/279 (63%), Gaps = 28/279 (10%) Query: 298 VSGNLLDVYSSQGVATPAIT--VSNSCPAELPNIKREISETEAKALLKERQKKDNHNLIE 355 +SG++LDVYS + +P S SCP+ LP +KREI+ET+ +AL KERQKKDNHNLIE Sbjct: 61 LSGSILDVYSGEQGISPINMGLTSASCPSSLP-MKREITETDTRALAKERQKKDNHNLIE 119 Query: 356 RRRRFNINDRIKELGTLIPKSSDPEMRWNKGTILKASVDYIRKLQKEQQRSKDLESRQRS 415 RRRR+NIN RIKELGTLIPKS+DP+MRWNKGTILKASV+YI+ LQKEQQR+++LE RQ+ Sbjct: 120 RRRRYNINYRIKELGTLIPKSNDPDMRWNKGTILKASVEYIKWLQKEQQRARELEHRQKK 179 Query: 416 LEQANRSLQLRIQELELQAQIHGLPVPPTPGLLSLATTSASDSLKPEQLDIEEEGRPGAA 475 LEQANR L LRIQELE+QA+ HGLP + G + L PEQ ++ Sbjct: 180 LEQANRRLLLRIQELEIQARTHGLPTLASLGTVDLGAHVTKQQSHPEQNSVDY------- 232 Query: 476 TFHVGGGPAQNAPHQQPPAPP-SDALLDLHFPSDHLGDLGDPFHLGLEDILMEEEEGVVG 534 Q Q P+P D + P + DL ++EE+ + G Sbjct: 233 --------CQQLTVSQGPSPELCDQAIAFSDPLSYFTDLS-------FSAALKEEQRLDG 277 Query: 535 GLSGGALSPLRAASDPLLSSVSPAVSKASSRRSSFSMEE 573 L +SP +DPLLS+ SPAVSK SSRRSSFS ++ Sbjct: 278 MLLDDTISPF--GTDPLLSATSPAVSKESSRRSSFSSDD 314 >gi|52630419 sterol regulatory element binding transcription factor 1 isoform a [Homo sapiens] Length = 1177 Score = 60.8 bits (146), Expect = 3e-09 Identities = 94/372 (25%), Positives = 140/372 (37%), Gaps = 45/372 (12%) Query: 60 DPDSFYELKSQPLPLRSSLPISLQATPATPATLSASSSAGG--SRTPAMSSSSSSRVLLR 117 D S L P L SSL L A P+ LS A P+M + S + Sbjct: 95 DTSSPGSLSPPPATLSSSLEAFLSGPQAAPSPLSPPQPAPTPLKMYPSMPAFSPGPGIKE 154 Query: 118 QQLMRAQAQEQERRERREQAAAAPFPSPAP----ASPAISVVGVSAGGHTLSRPPPAQVP 173 + + + Q + FP+PAP ++P + G T S P Q P Sbjct: 155 ESVPLSILQTPTPQPLPGALLPQSFPAPAPPQFSSTPVLGYPSPPGGFSTGSPPGNTQQP 214 Query: 174 REVLKVQTHLENPTRYHLQQARRQQVKQYLSTTLGPKLASQALTPPPGPASAQPLPAPEA 233 L + + P Q + +Q L+ T P A T + Q +P Sbjct: 215 LPGLPLASPPGVPPVSLHTQVQSVVPQQLLTVTAAPTAAPVTTTVT---SQIQQVPVLLQ 271 Query: 234 AHTTGPTGSAPNSPMALLTIGSSSEKEIDDVIDEIISLESSYNDEMLSYLPGGTTGLQLP 293 H + LLT + + LS L GTT P Sbjct: 272 PHFI-------KADSLLLTAMKTDGATVKAA--------------GLSPLVSGTTVQTGP 310 Query: 294 STLPVSGNLLDVYSSQGVATPAITVSNSCPAELPNIKREISETEAKALLKER-QKKDNHN 352 VSG + +AT + V AE I R + ++A A + R +K+ HN Sbjct: 311 LPTLVSGGTI-------LATVPLVVD----AEKLPINRLAAGSKAPASAQSRGEKRTAHN 359 Query: 353 LIERRRRFNINDRIKELGTLIPKSSDPEMRWNKGTILKASVDYIRKLQKEQQRSKDLESR 412 IE+R R +IND+I EL L+ + E + NK +L+ ++DYIR LQ Q+ K Sbjct: 360 AIEKRYRSSINDKIIELKDLVVGT---EAKLNKSAVLRKAIDYIRFLQHSNQKLKQENLS 416 Query: 413 QRSLEQANRSLQ 424 R+ ++SL+ Sbjct: 417 LRTAVHKSKSLK 428 >gi|22547195 sterol regulatory element binding transcription factor 1 isoform b [Homo sapiens] Length = 1147 Score = 60.8 bits (146), Expect = 3e-09 Identities = 94/372 (25%), Positives = 140/372 (37%), Gaps = 45/372 (12%) Query: 60 DPDSFYELKSQPLPLRSSLPISLQATPATPATLSASSSAGG--SRTPAMSSSSSSRVLLR 117 D S L P L SSL L A P+ LS A P+M + S + Sbjct: 65 DTSSPGSLSPPPATLSSSLEAFLSGPQAAPSPLSPPQPAPTPLKMYPSMPAFSPGPGIKE 124 Query: 118 QQLMRAQAQEQERRERREQAAAAPFPSPAP----ASPAISVVGVSAGGHTLSRPPPAQVP 173 + + + Q + FP+PAP ++P + G T S P Q P Sbjct: 125 ESVPLSILQTPTPQPLPGALLPQSFPAPAPPQFSSTPVLGYPSPPGGFSTGSPPGNTQQP 184 Query: 174 REVLKVQTHLENPTRYHLQQARRQQVKQYLSTTLGPKLASQALTPPPGPASAQPLPAPEA 233 L + + P Q + +Q L+ T P A T + Q +P Sbjct: 185 LPGLPLASPPGVPPVSLHTQVQSVVPQQLLTVTAAPTAAPVTTTVT---SQIQQVPVLLQ 241 Query: 234 AHTTGPTGSAPNSPMALLTIGSSSEKEIDDVIDEIISLESSYNDEMLSYLPGGTTGLQLP 293 H + LLT + + LS L GTT P Sbjct: 242 PHFI-------KADSLLLTAMKTDGATVKAA--------------GLSPLVSGTTVQTGP 280 Query: 294 STLPVSGNLLDVYSSQGVATPAITVSNSCPAELPNIKREISETEAKALLKER-QKKDNHN 352 VSG + +AT + V AE I R + ++A A + R +K+ HN Sbjct: 281 LPTLVSGGTI-------LATVPLVVD----AEKLPINRLAAGSKAPASAQSRGEKRTAHN 329 Query: 353 LIERRRRFNINDRIKELGTLIPKSSDPEMRWNKGTILKASVDYIRKLQKEQQRSKDLESR 412 IE+R R +IND+I EL L+ + E + NK +L+ ++DYIR LQ Q+ K Sbjct: 330 AIEKRYRSSINDKIIELKDLVVGT---EAKLNKSAVLRKAIDYIRFLQHSNQKLKQENLS 386 Query: 413 QRSLEQANRSLQ 424 R+ ++SL+ Sbjct: 387 LRTAVHKSKSLK 398 >gi|4507847 upstream stimulatory factor 2 isoform 1 [Homo sapiens] Length = 346 Score = 57.0 bits (136), Expect = 5e-08 Identities = 60/226 (26%), Positives = 98/226 (43%), Gaps = 42/226 (18%) Query: 215 ALTPPPGPASAQPLPAPEAAHTTGPTGSAPNSPMALLTIGSSSEKEIDDVIDEIISLESS 274 A + PPGPA+ PL + + G SP A E +S E+ Sbjct: 130 AASVPPGPAAPFPLAVIQNPFSNG------GSPAA-----------------EAVSGEAR 166 Query: 275 YNDEMLSYLP----GGTTGLQLPST---LPVSGNLLDVYSSQGVATPAITVSNSCPAELP 327 + +Y P G TT + + +T L G + + Q V T P P Sbjct: 167 F-----AYFPASSVGDTTAVSVQTTDQSLQAGGQFYVMMTPQDVLQTG-TQRTIAPRTHP 220 Query: 328 NIKREISETEAKALLKERQKKDNHNLIERRRRFNINDRIKELGTLIP--KSSDPEMRWNK 385 +I T ++ +++ HN +ERRRR IN+ I +L +IP + + + +K Sbjct: 221 -YSPKIDGTRTP---RDERRRAQHNEVERRRRDKINNWIVQLSKIIPDCNADNSKTGASK 276 Query: 386 GTILKASVDYIRKLQKEQQRSKDLESRQRSLEQANRSLQLRIQELE 431 G IL + DYIR+L++ QR ++ L+ N L+ +I+EL+ Sbjct: 277 GGILSKACDYIRELRQTNQRMQETFKEAERLQMDNELLRQQIEELK 322 >gi|27477113 sterol regulatory element-binding transcription factor 2 [Homo sapiens] Length = 1141 Score = 55.8 bits (133), Expect = 1e-07 Identities = 84/378 (22%), Positives = 151/378 (39%), Gaps = 66/378 (17%) Query: 86 PATPATLSASSSAGGSRTPAMSSSSSSRVLLRQQLMRAQAQEQERRERREQAAAAPFPSP 145 P + + S+S S+G S + + SSS + +R P SP Sbjct: 55 PGSGGSGSSSGSSGSSSSSSNGRGSSSGAV------------DPSVQRSFTQVTLPSFSP 102 Query: 146 APASPAISVVGVSAGGHTLS-----------RPPPAQVPREVLKVQTHLENPTRYHLQQA 194 + ASP + V ++ RP P P+ L+ QT + PT Q Sbjct: 103 SAASPQAPTLQVKVSPTSVPTTPRATPILQPRPQPQPQPQTQLQQQTVMITPTFSTTPQT 162 Query: 195 RRQQ---VKQYLSTT---LGPKLASQALTPPPGPASAQP-LPAPEAAHTTGPTGSAPNSP 247 R Q + Q +T+ L P++ S + P + Q + +A T + Sbjct: 163 RIIQQPLIYQNAATSFQVLQPQVQSLVTSSQVQPVTIQQQVQTVQAQRVLTQTANGTLQT 222 Query: 248 MALLTIGSSSEKEIDDVI----DEIISLES---------------SYNDEMLSYL--PGG 286 +A T+ + + ++ V +II +S + + L+ L P Sbjct: 223 LAPATVQTVAAPQVQQVPVLVQPQIIKTDSLVLTTLKTDGSPVMAAVQNPALTALTTPIQ 282 Query: 287 TTGLQLPSTLPVSGNLLDVYSSQGVATPAITVSNSCPAELPNIKREISETEAKALLKERQ 346 T LQ+P+ + SG +L P + P + + + + E KE + Sbjct: 283 TAALQVPTLVGSSGTIL-------TTMPVMMGQEKVP--IKQVPGGVKQLEPP---KEGE 330 Query: 347 KKDNHNLIERRRRFNINDRIKELGTLIPKSSDPEMRWNKGTILKASVDYIRKLQKEQQRS 406 ++ HN+IE+R R +IND+I EL L+ +D +M +K +L+ ++DYI+ LQ+ + Sbjct: 331 RRTTHNIIEKRYRSSINDKIIELKDLV-MGTDAKM--HKSGVLRKAIDYIKYLQQVNHKL 387 Query: 407 KDLESRQRSLEQANRSLQ 424 + + Q N+ L+ Sbjct: 388 RQENMVLKLANQKNKLLK 405 >gi|46877105 upstream stimulatory factor 2 isoform 2 [Homo sapiens] Length = 279 Score = 55.8 bits (133), Expect = 1e-07 Identities = 30/91 (32%), Positives = 54/91 (59%), Gaps = 2/91 (2%) Query: 343 KERQKKDNHNLIERRRRFNINDRIKELGTLIP--KSSDPEMRWNKGTILKASVDYIRKLQ 400 ++ +++ HN +ERRRR IN+ I +L +IP + + + +KG IL + DYIR+L+ Sbjct: 165 RDERRRAQHNEVERRRRDKINNWIVQLSKIIPDCNADNSKTGASKGGILSKACDYIRELR 224 Query: 401 KEQQRSKDLESRQRSLEQANRSLQLRIQELE 431 + QR ++ L+ N L+ +I+EL+ Sbjct: 225 QTNQRMQETFKEAERLQMDNELLRQQIEELK 255 >gi|19923312 v-myc myelocytomatosis viral related oncogene, neuroblastoma derived [Homo sapiens] Length = 464 Score = 52.8 bits (125), Expect = 9e-07 Identities = 76/344 (22%), Positives = 133/344 (38%), Gaps = 56/344 (16%) Query: 117 RQQLMRAQAQE-QERRERREQAAAAPFPSPAPASPAISVVGVSAGGHTLSRPPPAQVPRE 175 R++L RA +++ Q R + A P ASPA G +AG PA++ Sbjct: 123 REKLERAVSEKLQHGRGPPTAGSTAQSPGAGAASPAGRGHGGAAGAGRAGAALPAELAHP 182 Query: 176 VLK-VQTHLENPTRYHLQQARRQQVKQYLSTTLGPKLASQALTPPPGPASAQPLPAPEAA 234 + V + P + ++ + GP +AS A P A P P Sbjct: 183 AAECVDPAVVFPFPVNKREPAPVPAAPASAPAAGPAVASGAGIAAPAGAPGVAPPRPGGR 242 Query: 235 HTTGPTGSAPNSPMALLTIGSSSEKEIDDVIDE---------IISLE---SSYNDEMLSY 282 T+G AL T G + + DD DE ++++E SS N + ++ Sbjct: 243 QTSG------GDHKALSTSGEDTLSDSDDEDDEEEDEEEEIDVVTVEKRRSSSNTKAVTT 296 Query: 283 L------------PGGTTGLQLPSTLPVSGNLLDVYSSQGVATPAITVSNSCPAELPNIK 330 PG +L + L ++ A P+ V + IK Sbjct: 297 FTITVRPKNAALGPGRAQSSEL-----ILKRCLPIHQQHNYAAPSPYVESEDAPPQKKIK 351 Query: 331 REISETEAKALL--------------KERQKKDNHNLIERRRRFNINDRIKELGTLIPKS 376 E S K+++ ++ +++ NHN++ER+RR ++ L +P+ Sbjct: 352 SEASPRPLKSVIPPKAKSLSPRNSDSEDSERRRNHNILERQRRNDLRSSFLTLRDHVPEL 411 Query: 377 SDPEMRWNKGTILKASVDYIRKLQKEQQR----SKDLESRQRSL 416 E + K ILK + +Y+ LQ E+ + + L++RQ+ L Sbjct: 412 VKNE-KAAKVVILKKATEYVHSLQAEEHQLLLEKEKLQARQQQL 454 >gi|6005934 upstream stimulatory factor 1 isoform 1 [Homo sapiens] Length = 310 Score = 52.8 bits (125), Expect = 9e-07 Identities = 36/116 (31%), Positives = 64/116 (55%), Gaps = 9/116 (7%) Query: 335 ETEAKALLKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSS--DPEMRWNKGTILKAS 392 ++EA ++ +++ HN +ERRRR IN+ I +L +IP S + +KG IL + Sbjct: 188 KSEAPRTTRDEKRRAQHNEVERRRRDKINNWIVQLSKIIPDCSMESTKSGQSKGGILSKA 247 Query: 393 VDYIRKLQKEQQRSKDLESRQRSLEQANRSLQLRIQELE-----LQAQI--HGLPV 441 DYI++L++ R + L+ N L+ ++++L+ L+AQ+ HGL V Sbjct: 248 CDYIQELRQSNHRLSEELQGLDQLQLDNDVLRQQVEDLKNKNLLLRAQLRHHGLEV 303 >gi|46877102 upstream stimulatory factor 1 isoform 2 [Homo sapiens] Length = 251 Score = 52.8 bits (125), Expect = 9e-07 Identities = 36/116 (31%), Positives = 64/116 (55%), Gaps = 9/116 (7%) Query: 335 ETEAKALLKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSS--DPEMRWNKGTILKAS 392 ++EA ++ +++ HN +ERRRR IN+ I +L +IP S + +KG IL + Sbjct: 129 KSEAPRTTRDEKRRAQHNEVERRRRDKINNWIVQLSKIIPDCSMESTKSGQSKGGILSKA 188 Query: 393 VDYIRKLQKEQQRSKDLESRQRSLEQANRSLQLRIQELE-----LQAQI--HGLPV 441 DYI++L++ R + L+ N L+ ++++L+ L+AQ+ HGL V Sbjct: 189 CDYIQELRQSNHRLSEELQGLDQLQLDNDVLRQQVEDLKNKNLLLRAQLRHHGLEV 244 >gi|14602433 Williams Beuren syndrome chromosome region 14 isoform alpha [Homo sapiens] Length = 852 Score = 50.4 bits (119), Expect = 4e-06 Identities = 74/302 (24%), Positives = 120/302 (39%), Gaps = 72/302 (23%) Query: 134 REQAAAAPFPSPAPASPAISVVGVSAGGHTLSRPPPAQVPREVLKVQTHLENPTRYHLQQ 193 R Q A+ P +PA ASP + + L++ A P + L + L + T Sbjct: 501 RGQKASPPTLAPATASPPTTA---GSNNPCLTQLLTAAKPEQAL--EPPLVSSTLLRSPG 555 Query: 194 ARRQQVKQYLSTTLGPKLASQALTPPPGPAS---AQPLPAPEAAHTTGPTGSAPNSPMAL 250 + ++ V ++ T L P A PPPGPA+ ++PL P+A + P AP Sbjct: 556 SPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPP---AP------ 606 Query: 251 LTIGSSSEKEIDDVIDEIISLESSYNDEMLSYLPGGTTGLQLPSTLPVSGNLLDVYSSQG 310 S SE+ + LS +PG P TL V Sbjct: 607 ----SGSERRLSGD---------------LSSMPG-------PGTLSVR----------- 629 Query: 311 VATPAITVSNSCPAELPNIKREISETEAKALLKERQKKDNHNLIERRRRFNINDRIKELG 370 V+ P +S P R I+ A E++RRFNI L Sbjct: 630 VSPPQPILSRGRPDSNKTENRRITHISA----------------EQKRRFNIKLGFDTLH 673 Query: 371 TLIPK-SSDPEMRWNKGTILKASVDYIRKLQKEQQ-RSKDLESRQRSLEQANRSLQLRIQ 428 L+ S+ P ++ +K T L+ + +YI LQ+E+ ++ + + +E+ N ++ L Q Sbjct: 674 GLVSTLSAQPSLKVSKATTLQKTAEYILMLQQERAGLQEEAQQLRDEIEELNAAINLCQQ 733 Query: 429 EL 430 +L Sbjct: 734 QL 735 >gi|91208420 bassoon protein [Homo sapiens] Length = 3926 Score = 49.7 bits (117), Expect = 7e-06 Identities = 53/164 (32%), Positives = 69/164 (42%), Gaps = 24/164 (14%) Query: 83 QATPATPATLSASSSAGGSRTPAMSSSSSSRVLLRQQLMRAQAQEQERRERREQAAAAPF 142 Q + A+ A AS S GSR + S L + +AQ Q Q R QAA P Sbjct: 3707 QPSRASSAYHHASDSKKGSR----QAHSGPAALQSKAEPQAQPQLQGR-----QAAPGPQ 3757 Query: 143 PSPAPASPAISVVGVSAGGHTLSRPPPAQVPREVLKVQTHLENPTRYHLQQARRQQVKQY 202 S +P+S I SR P Q ++ L +Q P + L QAR QQ Q Sbjct: 3758 QSQSPSSRQIP-------SGAASRQPQTQQQQQGLGLQ-----PPQQALTQARLQQQSQP 3805 Query: 203 LSTTLGPKLASQALTPPPGPASA---QPLPAPEAAHTTGPTGSA 243 + P + A P PGP++A QP P A T G G+A Sbjct: 3806 TTRGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTA 3849 Score = 33.1 bits (74), Expect = 0.71 Identities = 49/196 (25%), Positives = 74/196 (37%), Gaps = 27/196 (13%) Query: 75 RSSLPISLQATPATPATLSASSSAGGSRTPAMSSSSSSRVLLR-----QQLMRAQAQEQE 129 R++ P QA+ TP S + ++ PA + R L+ Q+ R+ + + Sbjct: 90 RAASPTPKQASATTPGHESPRETR--AQGPAGQEADGPRRTLQVDSRTQRSGRSPSVSPD 147 Query: 130 RRERREQAAAAPFPSPAPASPAISVVGVSAGGHTLSRP---PPAQVPREVLKVQTHLENP 186 R + P +P P+S + S T S+P Q +V NP Sbjct: 148 RGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQPNFNTCTQCHNKVCNQCGFNPNP 207 Query: 187 TRYHLQQAR-------RQQVKQYLSTTLGPKLASQ------ALTPPPGPASAQPLPAPEA 233 HL Q + + Q + T P+ SQ AL+P PA QPL P+ Sbjct: 208 ---HLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALSPAHSPAK-QPLGKPDQ 263 Query: 234 AHTTGPTGSAPNSPMA 249 + GP G P S A Sbjct: 264 ERSRGPGGPQPGSRQA 279 Score = 30.8 bits (68), Expect = 3.5 Identities = 47/233 (20%), Positives = 75/233 (32%), Gaps = 35/233 (15%) Query: 60 DPDSFYELKSQPLPLRSSLPISLQATPATPAT--------------LSASSSAGGSRTPA 105 DP + + P + + P TPAT ++ +S AG R+P+ Sbjct: 1352 DPLKLHSSPASPSSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSERSPS 1411 Query: 106 MSSSSSSRVLLRQQLMRAQAQEQERRERREQAAAAPFPSPAPASPAISVVGVSAGGHTLS 165 SS++ S E + AAA P S + G S Sbjct: 1412 PSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYS 1471 Query: 166 RPPPAQVPREVLKVQTHLENPTRYHLQQARRQQVKQYLSTTLGPKLASQALTPPPGPASA 225 + P L + E+PT + +GP+ ++ T P PA A Sbjct: 1472 YFASSSPP---LSPSSPSESPT--------------FSPGKMGPRATAEFSTQTPSPAPA 1514 Query: 226 QPLPAPEAAHTTGPT----GSAPNSPMALLTIGSSSEKEIDDVIDEIISLESS 274 +P A T P P+ P + S +E ++ + S SS Sbjct: 1515 SDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASS 1567 >gi|114431248 hypothetical protein LOC205717 [Homo sapiens] Length = 2245 Score = 48.5 bits (114), Expect = 2e-05 Identities = 34/105 (32%), Positives = 57/105 (54%), Gaps = 6/105 (5%) Query: 332 EISETEAKALLKERQK-KDNHNLIERRRRFNINDRIKELGTLIPKSSDPEMRWNKGTILK 390 E++E E + R+K ++ HN +ER R+ IN I +G LIP S P ++ +K IL Sbjct: 3 EMTENETPTKKQHRKKNRETHNAVERHRKKKINAGINRIGELIPCS--PALKQSKNMILD 60 Query: 391 ASVDYIRKLQKEQQRSKDLESRQRSLEQANRSLQLRIQELELQAQ 435 + YI +L+++ + +L + EQA +LR Q E+Q + Sbjct: 61 QAFKYITELKRQ---NDELLLNGGNNEQAEEIKKLRKQLEEIQKE 102 >gi|47717116 MAX interactor 1 isoform b [Homo sapiens] Length = 295 Score = 47.8 bits (112), Expect = 3e-05 Identities = 60/252 (23%), Positives = 114/252 (45%), Gaps = 36/252 (14%) Query: 219 PPGPASAQPLPAPEAAHTTGPTGSAPNSPMALL--TIGSSSEKEIDDVIDEI-ISLESSY 275 PP A+ QP PE P G+ P P + + T +S EK I+ + + I LE++ Sbjct: 27 PPAVAAPQPPALPE-----DPAGAKPRCPFSDIFNTSENSMEKHINTFLQNVQILLEAA- 80 Query: 276 NDEMLSYLPGGTTGLQLPSTLPVSGNLLDVYSSQGVATPAITVSNSCPAELPNIKREISE 335 SYL ++ + G Y+S + P+ + +S P + ++ S Sbjct: 81 -----SYLEQ----IEKENKKCEHG-----YASSFPSMPSPRLQHSKPPRRLSRAQKHSS 126 Query: 336 TEAKALLKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSSDPEMRWNKGTILKASVDY 395 + R HN +E+ RR ++ ++ L LIP D G + KA + Sbjct: 127 GSSNTSTANRS---THNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKA-H 182 Query: 396 IRKLQKEQQRSKDLESRQRSLEQANRSLQLRIQELELQAQIHGLPVPPTPGLLSLATTSA 455 I+KL++ +++S + + +LE+ R L+ R+++L+ ++ + + S+ +T + Sbjct: 183 IKKLEEAERKS---QHQLENLEREQRFLKWRLEQLQGPQEMERIRMD------SIGSTIS 233 Query: 456 SDSLKPEQLDIE 467 SD E+ +IE Sbjct: 234 SDRSDSEREEIE 245 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 47.0 bits (110), Expect = 5e-05 Identities = 51/197 (25%), Positives = 73/197 (37%), Gaps = 19/197 (9%) Query: 68 KSQPLPLRSSLPISLQA-----TPATPA-TLSASSSAGGSRTPAMSSSSSSRVLLRQQLM 121 K+ P RS+L + TP TP+ ++ S A G+ + S+R + Sbjct: 146 KATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGP 205 Query: 122 RAQAQEQERRERREQAAAAPFPSPA------PASPAISVVGVSAGGHTLSRPPPAQVPRE 175 R E + AA A PAS ++S S P PR Sbjct: 206 RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPR- 264 Query: 176 VLKVQTHLENPTRYHLQQARRQQV---KQYLSTTLGPKLASQALTPPPGPASAQPLPAPE 232 H P LQ R QV ++ + LGP +S TP P A+P+P P+ Sbjct: 265 ---APAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPD 321 Query: 233 AAHTTGPTGSAPNSPMA 249 A T P P+ P+A Sbjct: 322 NAATPLPATLPPSPPLA 338 Score = 37.0 bits (84), Expect = 0.049 Identities = 34/120 (28%), Positives = 44/120 (36%), Gaps = 6/120 (5%) Query: 140 APFPSPAPASPAISVVGVSAGGHTLSRPPPAQVPREVLKV-QTHLENPTRYHLQQARRQQ 198 A FP AP SP+ S+ L+ PPP P + Q P LQ RR Sbjct: 805 ASFPGQAPFSPSASLPM-----SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPP 859 Query: 199 VKQYLSTTLGPKLASQALTPPPGPASAQPLPAPEAAHTTGPTGSAPNSPMALLTIGSSSE 258 ++ GP+L PP P S P G + SA ++P L S E Sbjct: 860 TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPE 919 Score = 36.2 bits (82), Expect = 0.084 Identities = 70/282 (24%), Positives = 105/282 (37%), Gaps = 48/282 (17%) Query: 68 KSQPLPLRSSLPISLQATPATPATLSASSSAGGSRTPAMSSSSSSRVLLRQQLMRAQAQE 127 K++P+P P ATP PATL S A S S+ L Q Sbjct: 313 KARPVP-----PPDNAATPL-PATLPPSPPLATPLPLAPPSPSAPPSL--------QTLP 358 Query: 128 QERRERREQAAAAPFPSPAPASPAISVVGVSAGGHTLSRP----PPAQVPREVLKVQTHL 183 QA + P A P++ + H+L+ P PP+ + L+ T L Sbjct: 359 SPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSL 418 Query: 184 ENPTRYHLQQARRQQVKQYLSTTLGPKLASQALTPPPGPASAQP----------LPA-PE 232 +PT Q +L T+ P+ +LT P PAS P LPA P Sbjct: 419 GSPTL--------QATHSFL--TMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPP 468 Query: 233 AAHTTGPTGSAPNSPM------ALLTIGS-SSEKEIDDVIDEIISLESSYNDEMLSYLPG 285 + P S +SP+ AL ++ S S + + +I + +SS L P Sbjct: 469 LQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPA 528 Query: 286 GTTGLQLPSTLPVSGNLLDVYSSQGVATPAITVSNSCPAELP 327 T L + ++ L +S + TP + + CPA P Sbjct: 529 SLTTPPLENLPSLAPPPLQT-ASAPLTTPHLE-TPPCPAPCP 568 >gi|9945318 MAX binding protein [Homo sapiens] Length = 582 Score = 47.0 bits (110), Expect = 5e-05 Identities = 73/316 (23%), Positives = 117/316 (37%), Gaps = 49/316 (15%) Query: 218 PPPGPASAQPLP-APEAAHTTGPTGSAPNSPMALLTIGSSSEKEIDDVIDEIISLESSYN 276 PPP PA+AQPLP AP G G + P L + ++ + Sbjct: 104 PPPLPAAAQPLPLAPRQPALVGAPGLSIKEPAPLPS------------RPQVPTPAPLLP 151 Query: 277 DEMLSYLPGGTTGLQLPSTLPVSGNLLDVYSSQGVATPAITVSNSCPAELPNIK----RE 332 D + P G+ P PV L + GV P + P L +K E Sbjct: 152 DSKATIPPNGSPKPLQPLPTPV----LTIAPHPGV-QPQLAPQQPPPPTLGTLKLAPAEE 206 Query: 333 ISETEAKALLKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSSDPEMRWNKGTILKAS 392 + +E K ++ HN +E+ RR ++ + + L IP D + + ++L+ + Sbjct: 207 VKSSEQKKRPGGIGTREVHNKLEKNRRAHLKECFETLKRNIPNVDD--KKTSNLSVLRTA 264 Query: 393 VDYIRKLQKEQQRSKDLESRQRSLEQANRSLQLRIQEL--ELQAQIHGLPV--------P 442 + YI+ L++++ K+ E L + + Q R+ EL EL + L + Sbjct: 265 LRYIQSLKRKE---KEYEHEMERLAREKIATQQRLAELKHELSQWMDVLEIDRVLRQTGQ 321 Query: 443 PTPGLLSLATTSASDSLKPEQLDIEEEG--------RPGAATFHVGGGPAQNAPHQQP-- 492 P S +T S + E ++ + G RP P P P Sbjct: 322 PEDDQASTSTASEGEDNIDEDMEEDRAGLGPPKLSHRPQPELLKSTLPPPSTTPAPLPPH 381 Query: 493 --PAPPSDALLDLHFP 506 P P S AL H P Sbjct: 382 PHPHPHSVALPPAHLP 397 Score = 30.8 bits (68), Expect = 3.5 Identities = 25/112 (22%), Positives = 43/112 (38%), Gaps = 13/112 (11%) Query: 130 RRERREQAAAAPFPSPAPASPAISVVG------VSAGGHTLSRPPPAQVPREVLKVQTHL 183 ++++ +Q P P P PA+PA ++V +AGG + A V++ H+ Sbjct: 399 QQQQPQQKTPLPAPPPPPAAPAQTLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHV 458 Query: 184 ENPTRYHLQQARRQQVKQYLSTTLGPKLASQALTPPPGPASAQPLPAPEAAH 235 LQ + + + P + TPP G + P AH Sbjct: 459 -------LQGPGGKHIAHIAPSAPSPAVQLAPATPPIGHITVHPATLNHVAH 503 >gi|4758010 clock [Homo sapiens] Length = 846 Score = 45.8 bits (107), Expect = 1e-04 Identities = 24/71 (33%), Positives = 45/71 (63%), Gaps = 3/71 (4%) Query: 343 KERQKKDNHNLIERRRRFNINDRIKELGTLIPKSSDPEMRWNKGTILKASVDYIRKLQKE 402 K++ K+ + N E++RR N IKELG+++P ++ + +K T+L+ S+D++RK ++ Sbjct: 31 KDKAKRVSRNKSEKKRRDQFNVLIKELGSMLPGNA---RKMDKSTVLQKSIDFLRKHKEI 87 Query: 403 QQRSKDLESRQ 413 +S E RQ Sbjct: 88 TAQSDASEIRQ 98 >gi|30795240 aryl hydrocarbon receptor nuclear translocator isoform 2 [Homo sapiens] Length = 328 Score = 45.4 bits (106), Expect = 1e-04 Identities = 26/75 (34%), Positives = 42/75 (56%) Query: 334 SETEAKALLKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSSDPEMRWNKGTILKASV 393 S+ E + KER ++NH+ IERRRR + I EL ++P S + +K TIL+ +V Sbjct: 77 SDDEQSSADKERLARENHSEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAV 136 Query: 394 DYIRKLQKEQQRSKD 408 +++ L+ S D Sbjct: 137 SHMKSLRGTGNTSTD 151 >gi|4502231 aryl hydrocarbon receptor nuclear translocator isoform 1 [Homo sapiens] Length = 789 Score = 45.4 bits (106), Expect = 1e-04 Identities = 26/75 (34%), Positives = 42/75 (56%) Query: 334 SETEAKALLKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSSDPEMRWNKGTILKASV 393 S+ E + KER ++NH+ IERRRR + I EL ++P S + +K TIL+ +V Sbjct: 77 SDDEQSSADKERLARENHSEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAV 136 Query: 394 DYIRKLQKEQQRSKD 408 +++ L+ S D Sbjct: 137 SHMKSLRGTGNTSTD 151 >gi|5453734 MAD4 [Homo sapiens] Length = 209 Score = 44.3 bits (103), Expect = 3e-04 Identities = 26/101 (25%), Positives = 61/101 (60%), Gaps = 5/101 (4%) Query: 335 ETEAKALLKER-QKKDNHNLIERRRRFNINDRIKELGTLIPKSSDPEMRWNKGTILKASV 393 +T+A L+++ + +HN +E+ RR + +++L L+P D R ++LK + Sbjct: 41 KTKAAGLVRKAPNNRSSHNELEKHRRAKLRLYLEQLKQLVPLGPD-STRHTTLSLLKRAK 99 Query: 394 DYIRKLQKEQQRSKDLESRQRSLEQANRSLQLRIQELELQA 434 +I+KL+++ +R+ ++ + L+Q +R L+ R+++L +Q+ Sbjct: 100 VHIKKLEEQDRRALSIKEQ---LQQEHRFLKRRLEQLSVQS 137 >gi|146134388 YLP motif containing 1 [Homo sapiens] Length = 2146 Score = 43.5 bits (101), Expect = 5e-04 Identities = 70/279 (25%), Positives = 106/279 (37%), Gaps = 38/279 (13%) Query: 86 PATPATLSASSSAGG---SRTPAMSSSSSSRVLLRQQLMRAQAQEQERRERREQAAAAPF 142 P P L +S G S TPA + SSS + R+Q + Q Q+ +++ Q P Sbjct: 21 PPPPVALPEASPGPGYSSSTTPA-APSSSGFMSFREQHLAQLQQLQQMHQKQMQCVLQPH 79 Query: 143 PSPAPASPAISVVGVSAGGHTLSRPPPAQVPREVLKVQTHLENPTRYHLQQARRQQVKQY 202 P P P V + GG+ +PPP +P P L ++QQ K Sbjct: 80 HLPPPPLPPPPV--MPGGGYGDWQPPPPPMP-----------PPPGPALSYQKQQQYKHQ 126 Query: 203 L--STTLGP------KLASQALTPPPGPASAQP-----LPAPEAAHT-TGPTGSAPNSPM 248 + GP +L S +PP P S P +P P+ + PT S P P Sbjct: 127 MLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPP 186 Query: 249 ALLTIGSSSEKEIDDVIDEIISLESSYNDEMLSYLPGGTTGLQLPSTLPVSGNLLDVYSS 308 A + S + S SS + LS+ Q + P G+ S Sbjct: 187 AQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGH----SKS 242 Query: 309 QGVATPAITVSNSCPAELPNIKREISETEAKALLKERQK 347 Q +A P ++ P +++E E+ AK E+Q+ Sbjct: 243 QLLAPPP---PSAPPGNKTTVQQEPLESGAKNKSTEQQQ 278 Score = 30.0 bits (66), Expect = 6.0 Identities = 47/195 (24%), Positives = 67/195 (34%), Gaps = 27/195 (13%) Query: 61 PDSFYELKSQPLPLRSSLPISLQATPATPATLSASSSAGGSRTPAMSSSSSSRVLLRQQL 120 P S+Y P SS P A P+ + + S + + + SSSSS L Q Sbjct: 171 PPSYY-------PPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQS 223 Query: 121 MRAQAQEQERR----ERREQAAAAPFPSPAPAS-PAISVVGVSAGGHTLSRPPPAQVPRE 175 +Q R + Q A P PS P + + + +G S P Sbjct: 224 YLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEP 283 Query: 176 VLKVQTHLENPTRYHLQQ--ARRQQVKQYLSTTLGPKLASQALTPPPGPASAQPLPAPEA 233 T E ++ Q + +Q+ K +L G K GP A+ P P Sbjct: 284 DPSTMTPQEQQQYWYRQHLLSLQQRTKVHLP---GHK---------KGPVVAKDTPEPVK 331 Query: 234 AHTTGP-TGSAPNSP 247 T P T P SP Sbjct: 332 EEVTVPATSQVPESP 346 >gi|56549694 enabled homolog isoform a [Homo sapiens] Length = 591 Score = 43.1 bits (100), Expect = 7e-04 Identities = 42/136 (30%), Positives = 54/136 (39%), Gaps = 25/136 (18%) Query: 117 RQQLMRAQAQEQER----RERREQAAAAPFPSPAPASPAISVVGVSAGGHTLSRPPPAQV 172 RQ+ R + E+E+ RERR +AAAP P + + S G + PA+ Sbjct: 242 RQERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEPG-LQAASQPAET 300 Query: 173 PREVLKVQTHLENPTRYHLQQARRQQVKQYLSTTLGPKLASQALTPPPGPASAQPLPAPE 232 P + V L P L GP AS AL PPPGP PLP Sbjct: 301 PSQQGIVLGPLAPPPPPPLPP--------------GPAQASVALPPPPGPPPPPPLP--- 343 Query: 233 AAHTTGPTGSAPNSPM 248 +TGP P P+ Sbjct: 344 ---STGPPPPPPPPPL 356 Score = 35.0 bits (79), Expect = 0.19 Identities = 35/175 (20%), Positives = 63/175 (36%), Gaps = 25/175 (14%) Query: 332 EISETEAKALLKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSSDPEMRWNKGTILKA 391 E E + L +ERQ+++ +ER+ R +R++ L Sbjct: 182 ERERLEQEQLERERQERERQERLERQERLERQERLERQERL------------------- 222 Query: 392 SVDYIRKLQKEQQRSKDLESRQRSLEQANRSLQLRIQELELQAQIHGLPVPPTPGLLSLA 451 R+ Q+ Q+R + LE +R ++ R QL ++LE + + + P + Sbjct: 223 ----DRERQERQERER-LERLERERQERERQEQLEREQLEWERE-RRISSAAAPASVETP 276 Query: 452 TTSASDSLKPEQLDIEEEGRPGAATFHVGGGPAQNAPHQQPPAPPSDALLDLHFP 506 S + ++ +P G AP PP PP A + P Sbjct: 277 LNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALP 331 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.309 0.127 0.350 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 25,584,215 Number of Sequences: 37866 Number of extensions: 1426157 Number of successful extensions: 14255 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 126 Number of HSP's successfully gapped in prelim test: 741 Number of HSP's that attempted gapping in prelim test: 11330 Number of HSP's gapped (non-prelim): 3366 length of query: 575 length of database: 18,247,518 effective HSP length: 108 effective length of query: 467 effective length of database: 14,157,990 effective search space: 6611781330 effective search space used: 6611781330 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.