BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|84662753 G protein-coupled receptor 149 [Homo sapiens] (731 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|84662753 G protein-coupled receptor 149 [Homo sapiens] 1467 0.0 gi|15150803 opsin 4 isoform 1 [Homo sapiens] 45 2e-04 gi|71999143 opsin 4 isoform 2 [Homo sapiens] 44 4e-04 gi|61744454 retinal G-protein coupled receptor isoform 2 [Homo s... 42 0.002 gi|61744452 retinal G-protein coupled receptor isoform 3 [Homo s... 42 0.002 gi|4885341 G protein-coupled receptor 6 [Homo sapiens] 40 0.008 gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens] 39 0.013 gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens] 39 0.013 gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens] 39 0.013 gi|21361329 retinal G-protein coupled receptor isoform 1 [Homo s... 39 0.017 gi|119220588 melanin-concentrating hormone receptor 2 [Homo sapi... 39 0.017 gi|93277083 melanin-concentrating hormone receptor 2 [Homo sapiens] 39 0.017 gi|28557751 olfactory receptor, family 2, subfamily L, member 13... 39 0.022 gi|4503459 sphingosine-1-phosphate receptor 4 precursor [Homo sa... 38 0.029 gi|116284382 G protein-coupled bile acid receptor 1 [Homo sapiens] 38 0.038 gi|116284384 G protein-coupled bile acid receptor 1 [Homo sapiens] 38 0.038 gi|24850109 G protein-coupled bile acid receptor 1 [Homo sapiens] 38 0.038 gi|4507381 thromboxane A2 receptor [Homo sapiens] 37 0.065 gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens] 37 0.085 gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens] 37 0.085 gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens] 37 0.085 gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens] 37 0.085 gi|4557265 beta-1-adrenergic receptor [Homo sapiens] 37 0.085 gi|13540517 endothelial differentiation, sphingolipid G-protein-... 35 0.19 gi|9951913 G protein-coupled receptor 162 isoform 2 [Homo sapiens] 35 0.25 gi|55956923 5-hydroxytryptamine (serotonin) receptor 1A [Homo sa... 35 0.32 gi|6912348 lysophosphatidic acid receptor 3 [Homo sapiens] 35 0.32 gi|4885325 G protein-coupled receptor 3 [Homo sapiens] 34 0.42 gi|126362971 serine/threonine kinase 10 [Homo sapiens] 34 0.55 gi|122937311 solute carrier family 35, member F4 [Homo sapiens] 34 0.55 >gi|84662753 G protein-coupled receptor 149 [Homo sapiens] Length = 731 Score = 1467 bits (3799), Expect = 0.0 Identities = 731/731 (100%), Positives = 731/731 (100%) Query: 1 MSLFLSNLSTNDSSLWKENHNSTDLLNPPGTLNIYLFCLTCLMTFAALVGSIYSLISLLK 60 MSLFLSNLSTNDSSLWKENHNSTDLLNPPGTLNIYLFCLTCLMTFAALVGSIYSLISLLK Sbjct: 1 MSLFLSNLSTNDSSLWKENHNSTDLLNPPGTLNIYLFCLTCLMTFAALVGSIYSLISLLK 60 Query: 61 MQNRTVVSMLVASWSVDDLMSVLSVTIFMFLQWPNEVPGYFQFLCTTSALMYLCQGLSSN 120 MQNRTVVSMLVASWSVDDLMSVLSVTIFMFLQWPNEVPGYFQFLCTTSALMYLCQGLSSN Sbjct: 61 MQNRTVVSMLVASWSVDDLMSVLSVTIFMFLQWPNEVPGYFQFLCTTSALMYLCQGLSSN 120 Query: 121 LKATLLVSYNFYTMHRGVGSQTASRRSGQVLGVVLTVWAASLLLSALPLCGWGAFVRTPW 180 LKATLLVSYNFYTMHRGVGSQTASRRSGQVLGVVLTVWAASLLLSALPLCGWGAFVRTPW Sbjct: 121 LKATLLVSYNFYTMHRGVGSQTASRRSGQVLGVVLTVWAASLLLSALPLCGWGAFVRTPW 180 Query: 181 GCLVDCSSSYVLFLSIVYALAFGLLVGLSVPLTHRLLCSEEPPRLHSNYQEISRGASIPG 240 GCLVDCSSSYVLFLSIVYALAFGLLVGLSVPLTHRLLCSEEPPRLHSNYQEISRGASIPG Sbjct: 181 GCLVDCSSSYVLFLSIVYALAFGLLVGLSVPLTHRLLCSEEPPRLHSNYQEISRGASIPG 240 Query: 241 TPPTAGRVVSLSPEDAPGPSLRRSGGCSPSSDTVFGPGAPAAAGAEACRRENRGTLYGTR 300 TPPTAGRVVSLSPEDAPGPSLRRSGGCSPSSDTVFGPGAPAAAGAEACRRENRGTLYGTR Sbjct: 241 TPPTAGRVVSLSPEDAPGPSLRRSGGCSPSSDTVFGPGAPAAAGAEACRRENRGTLYGTR 300 Query: 301 SFTVSVAQKRFALILALTKVVLWLPMMMHMVVQNVVGFQSLPLETFSFLLTLLATTVTPV 360 SFTVSVAQKRFALILALTKVVLWLPMMMHMVVQNVVGFQSLPLETFSFLLTLLATTVTPV Sbjct: 301 SFTVSVAQKRFALILALTKVVLWLPMMMHMVVQNVVGFQSLPLETFSFLLTLLATTVTPV 360 Query: 361 FVLSKRWTHLPCGCIINCRQNAYAVASDGKKIKRKGFEFNLSFQKSYGIYKIAHEDYYDD 420 FVLSKRWTHLPCGCIINCRQNAYAVASDGKKIKRKGFEFNLSFQKSYGIYKIAHEDYYDD Sbjct: 361 FVLSKRWTHLPCGCIINCRQNAYAVASDGKKIKRKGFEFNLSFQKSYGIYKIAHEDYYDD 420 Query: 421 DENSIFYHNLMNSECETTKDPQRDNRNIFNAIKVEISTTPSLDSSTQRGINKCTNTDITE 480 DENSIFYHNLMNSECETTKDPQRDNRNIFNAIKVEISTTPSLDSSTQRGINKCTNTDITE Sbjct: 421 DENSIFYHNLMNSECETTKDPQRDNRNIFNAIKVEISTTPSLDSSTQRGINKCTNTDITE 480 Query: 481 AKQDSNNKKDAFSDKTGGDINYEETTFSEGPERRLSHEESQKPDLSDWEWCRSKSERTPR 540 AKQDSNNKKDAFSDKTGGDINYEETTFSEGPERRLSHEESQKPDLSDWEWCRSKSERTPR Sbjct: 481 AKQDSNNKKDAFSDKTGGDINYEETTFSEGPERRLSHEESQKPDLSDWEWCRSKSERTPR 540 Query: 541 QRSGYALAIPLCAFQGTVSLHAPTGKTLSLSTYEVSAEGQKITPASKKIEVYRSKSVGHE 600 QRSGYALAIPLCAFQGTVSLHAPTGKTLSLSTYEVSAEGQKITPASKKIEVYRSKSVGHE Sbjct: 541 QRSGYALAIPLCAFQGTVSLHAPTGKTLSLSTYEVSAEGQKITPASKKIEVYRSKSVGHE 600 Query: 601 PNSEDSSSTFVDTSVKIHLEVLEICDNEEALDTVSIISNISQSSTQVRSPSLRYSRKENR 660 PNSEDSSSTFVDTSVKIHLEVLEICDNEEALDTVSIISNISQSSTQVRSPSLRYSRKENR Sbjct: 601 PNSEDSSSTFVDTSVKIHLEVLEICDNEEALDTVSIISNISQSSTQVRSPSLRYSRKENR 660 Query: 661 FVSCDLGETASYSLFLPTSNPDGDINISIPDTVEAHRQNSKRQHQERDGYQEEIQLLNKA 720 FVSCDLGETASYSLFLPTSNPDGDINISIPDTVEAHRQNSKRQHQERDGYQEEIQLLNKA Sbjct: 661 FVSCDLGETASYSLFLPTSNPDGDINISIPDTVEAHRQNSKRQHQERDGYQEEIQLLNKA 720 Query: 721 YRKREEESKGS 731 YRKREEESKGS Sbjct: 721 YRKREEESKGS 731 >gi|15150803 opsin 4 isoform 1 [Homo sapiens] Length = 478 Score = 45.4 bits (106), Expect = 2e-04 Identities = 50/202 (24%), Positives = 86/202 (42%), Gaps = 16/202 (7%) Query: 5 LSNLSTNDSSLWKENHNSTDLLNPPGTLNIYLFCLTCLMTFAALVGSIYSLISLLKMQN- 63 L ++S W ++ P + L + L+ ++G++ + + + ++ Sbjct: 42 LPSISPTAPGTWAAAWVPLPTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRSRSL 101 Query: 64 RTVVSMLVASWSVDD-LMSVLSVTIF----MFLQWPNEVPGYFQFLCTTSALMYLCQGLS 118 RT +M + + +V D LMS +F ++ QW G +F AL G+S Sbjct: 102 RTPANMFIINLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGC-EFYAFCGALF----GIS 156 Query: 119 SNLKATLLVSYNFYTMHRGVGS-QTASRRSGQVLGVVLTVWAASLLLSALPLCGWGAFVR 177 S + T + + + R + + AS+R V+L VW +L S P GW A+V Sbjct: 157 SMITLTAIALDRYLVITRPLATFGVASKRRAAF--VLLGVWLYALAWSLPPFFGWSAYV- 213 Query: 178 TPWGCLVDCSSSYVLFLSIVYA 199 P G L CS Y+ F V A Sbjct: 214 -PEGLLTSCSWDYMSFTPAVRA 234 >gi|71999143 opsin 4 isoform 2 [Homo sapiens] Length = 489 Score = 44.3 bits (103), Expect = 4e-04 Identities = 45/167 (26%), Positives = 71/167 (42%), Gaps = 14/167 (8%) Query: 34 IYLFCLTCLMTFAALVGSIYSLISLLKMQNRTVVSMLVASWSVDDLMSVLSVTIFMFLQW 93 IY FC L ++ S SL N ++++ V+ + + + + T ++ QW Sbjct: 92 IYTFCRAVLRGVTVMMQSR----SLRTPANMFIINLAVSDFLMSFTQAPVFFTSSLYKQW 147 Query: 94 PNEVPGYFQFLCTTSALMYLCQGLSSNLKATLLVSYNFYTMHRGVGS-QTASRRSGQVLG 152 G +F AL G+SS + T + + + R + + AS+R Sbjct: 148 LFGETGC-EFYAFCGALF----GISSMITLTAIALDRYLVITRPLATFGVASKRRAAF-- 200 Query: 153 VVLTVWAASLLLSALPLCGWGAFVRTPWGCLVDCSSSYVLFLSIVYA 199 V+L VW +L S P GW A+V P G L CS Y+ F V A Sbjct: 201 VLLGVWLYALAWSLPPFFGWSAYV--PEGLLTSCSWDYMSFTPAVRA 245 >gi|61744454 retinal G-protein coupled receptor isoform 2 [Homo sapiens] Length = 291 Score = 42.4 bits (98), Expect = 0.002 Identities = 43/185 (23%), Positives = 78/185 (42%), Gaps = 20/185 (10%) Query: 28 PPGTLNIYLFCLTCLMTFAALVGSIYSLISLLKM----QNRTVVSMLVASWSVDD----L 79 P G + + + ++ AL G + +++ + RT +LV S ++ D L Sbjct: 8 PTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISL 67 Query: 80 MSVLSVTIFMFLQWPNEVPGYFQFLCTTSALMYLCQGLSSNLKATLLVSYNFYTMHRGVG 139 ++++ T + +WP G C L+S + + ++ H Sbjct: 68 NALVAATSSLLRRWPYGSDG-----CQAHGFQGFVTALASICSSAAIAWGRYH--HYCTR 120 Query: 140 SQTASRRSGQVLGVVLTVWAASLLLSALPLCGWGAFVRTPWG--CLVDCSSSYVLFLSIV 197 SQ A + + +VL VW +S +ALPL GWG + P G C +D S F S + Sbjct: 121 SQLAWNSA---VSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFL 177 Query: 198 YALAF 202 + ++F Sbjct: 178 FTMSF 182 >gi|61744452 retinal G-protein coupled receptor isoform 3 [Homo sapiens] Length = 253 Score = 42.4 bits (98), Expect = 0.002 Identities = 43/185 (23%), Positives = 78/185 (42%), Gaps = 20/185 (10%) Query: 28 PPGTLNIYLFCLTCLMTFAALVGSIYSLISLLKM----QNRTVVSMLVASWSVDD----L 79 P G + + + ++ AL G + +++ + RT +LV S ++ D L Sbjct: 8 PTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISL 67 Query: 80 MSVLSVTIFMFLQWPNEVPGYFQFLCTTSALMYLCQGLSSNLKATLLVSYNFYTMHRGVG 139 ++++ T + +WP G C L+S + + ++ H Sbjct: 68 NALVAATSSLLRRWPYGSDG-----CQAHGFQGFVTALASICSSAAIAWGRYH--HYCTR 120 Query: 140 SQTASRRSGQVLGVVLTVWAASLLLSALPLCGWGAFVRTPWG--CLVDCSSSYVLFLSIV 197 SQ A + + +VL VW +S +ALPL GWG + P G C +D S F S + Sbjct: 121 SQLAWNSA---VSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFL 177 Query: 198 YALAF 202 + ++F Sbjct: 178 FTMSF 182 >gi|4885341 G protein-coupled receptor 6 [Homo sapiens] Length = 362 Score = 40.0 bits (92), Expect = 0.008 Identities = 52/196 (26%), Positives = 84/196 (42%), Gaps = 30/196 (15%) Query: 64 RTVVSMLVASWSVDDLMSVLSVTIFMFLQWPNEVPGYFQFLCTTSALMY-LCQGLSSNLK 122 RT + +LV S + DL++ + + Q+ VP L T L+ +SS L Sbjct: 104 RTPMFVLVGSLATADLLAGCGLILHFVFQYL--VPSETVSLLTVGFLVASFAASVSSLLA 161 Query: 123 ATL---LVSYNFYTMHRGVGSQTASRRSGQVLGVVLTV---WAASLLLSALPLCGWGAFV 176 T+ L YN T + SRR+ +LGV L + W SL L LP+ GW Sbjct: 162 ITVDRYLSLYNALTYY--------SRRT--LLGVHLLLAATWTVSLGLGLLPVLGWNCLA 211 Query: 177 -RTPWGCLVDCSSSYVLFLSIVYALAFGLLVGLSVPL-------THRLLCSEE---PPRL 225 R + + S+V LS + + FG+++ L V + H++ + PP L Sbjct: 212 ERAACSVVRPLARSHVALLSAAFFMVFGIMLHLYVRICQVVWRHAHQIALQQHCLAPPHL 271 Query: 226 HSNYQEISRGASIPGT 241 + + + A + GT Sbjct: 272 AATRKGVGTLAVVLGT 287 >gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens] Length = 432 Score = 39.3 bits (90), Expect = 0.013 Identities = 46/188 (24%), Positives = 81/188 (43%), Gaps = 38/188 (20%) Query: 42 LMTFAALVGSIYSLIS------LLKMQNRTVVSMLVASWSVD-DLMSVLSVTIFMFLQWP 94 L+T + G+ +IS L + N +VS+ +A SV +M +SVT + +W Sbjct: 90 LITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKW- 148 Query: 95 NEVPGYF--------QFLCTTSALMYLCQ-GLSSNLKATLLVSYNFYTMHRGVGSQTASR 145 + G+F +C T+++M LC + L T ++Y R Sbjct: 149 --IFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPV-------------R 193 Query: 146 RSGQVLG-VVLTVWAASLLLSALPLCGWGAFVRTPWGCLVDCSSSYVLFLSIVYALAFGL 204 ++G+ + ++L+VW S ++ PL GW V CL+ Y +Y+ A Sbjct: 194 QNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYT-----IYSTAVAF 248 Query: 205 LVGLSVPL 212 + +SV L Sbjct: 249 YIPMSVML 256 >gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens] Length = 479 Score = 39.3 bits (90), Expect = 0.013 Identities = 46/188 (24%), Positives = 81/188 (43%), Gaps = 38/188 (20%) Query: 42 LMTFAALVGSIYSLIS------LLKMQNRTVVSMLVASWSVD-DLMSVLSVTIFMFLQWP 94 L+T + G+ +IS L + N +VS+ +A SV +M +SVT + +W Sbjct: 90 LITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKW- 148 Query: 95 NEVPGYF--------QFLCTTSALMYLCQ-GLSSNLKATLLVSYNFYTMHRGVGSQTASR 145 + G+F +C T+++M LC + L T ++Y R Sbjct: 149 --IFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPV-------------R 193 Query: 146 RSGQVLG-VVLTVWAASLLLSALPLCGWGAFVRTPWGCLVDCSSSYVLFLSIVYALAFGL 204 ++G+ + ++L+VW S ++ PL GW V CL+ Y +Y+ A Sbjct: 194 QNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYT-----IYSTAVAF 248 Query: 205 LVGLSVPL 212 + +SV L Sbjct: 249 YIPMSVML 256 >gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens] Length = 445 Score = 39.3 bits (90), Expect = 0.013 Identities = 46/188 (24%), Positives = 81/188 (43%), Gaps = 38/188 (20%) Query: 42 LMTFAALVGSIYSLIS------LLKMQNRTVVSMLVASWSVD-DLMSVLSVTIFMFLQWP 94 L+T + G+ +IS L + N +VS+ +A SV +M +SVT + +W Sbjct: 90 LITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKW- 148 Query: 95 NEVPGYF--------QFLCTTSALMYLCQ-GLSSNLKATLLVSYNFYTMHRGVGSQTASR 145 + G+F +C T+++M LC + L T ++Y R Sbjct: 149 --IFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPV-------------R 193 Query: 146 RSGQVLG-VVLTVWAASLLLSALPLCGWGAFVRTPWGCLVDCSSSYVLFLSIVYALAFGL 204 ++G+ + ++L+VW S ++ PL GW V CL+ Y +Y+ A Sbjct: 194 QNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYT-----IYSTAVAF 248 Query: 205 LVGLSVPL 212 + +SV L Sbjct: 249 YIPMSVML 256 >gi|21361329 retinal G-protein coupled receptor isoform 1 [Homo sapiens] Length = 295 Score = 38.9 bits (89), Expect = 0.017 Identities = 20/54 (37%), Positives = 30/54 (55%), Gaps = 2/54 (3%) Query: 151 LGVVLTVWAASLLLSALPLCGWGAFVRTPWG--CLVDCSSSYVLFLSIVYALAF 202 + +VL VW +S +ALPL GWG + P G C +D S F S ++ ++F Sbjct: 133 VSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTMSF 186 >gi|119220588 melanin-concentrating hormone receptor 2 [Homo sapiens] Length = 340 Score = 38.9 bits (89), Expect = 0.017 Identities = 38/160 (23%), Positives = 77/160 (48%), Gaps = 16/160 (10%) Query: 48 LVGSIYSLISLLKMQNRTVVSMLVASWSVDDLMSVLSVTIFMFLQWPNEVPGYFQF---L 104 LVG+I + ++++ + +TV + + + +V DL+ ++ + F+ QW G + F L Sbjct: 49 LVGNILIVFTIIRSRKKTVPDIYICNLAVADLVHIVGMP-FLIHQWAR--GGEWVFGGPL 105 Query: 105 CTTSALMYLCQGLSSNLKATLLVSYNFYTMHRGVGSQTASRRSGQVLGVVLTVWAASLLL 164 CT + C + + T++ ++ + + T R + + + L +WAAS +L Sbjct: 106 CTIITSLDTCNQFACSAIMTVMSVDRYFALVQPF-RLTRWRTRYKTIRINLGLWAASFIL 164 Query: 165 SALPLCGWGAFVRTPWG---CLVDCSSS-----YVLFLSI 196 ALP+ + ++ G C D +S Y L+L+I Sbjct: 165 -ALPVWVYSKVIKFKDGVESCAFDLTSPDDVLWYTLYLTI 203 >gi|93277083 melanin-concentrating hormone receptor 2 [Homo sapiens] Length = 340 Score = 38.9 bits (89), Expect = 0.017 Identities = 38/160 (23%), Positives = 77/160 (48%), Gaps = 16/160 (10%) Query: 48 LVGSIYSLISLLKMQNRTVVSMLVASWSVDDLMSVLSVTIFMFLQWPNEVPGYFQF---L 104 LVG+I + ++++ + +TV + + + +V DL+ ++ + F+ QW G + F L Sbjct: 49 LVGNILIVFTIIRSRKKTVPDIYICNLAVADLVHIVGMP-FLIHQWAR--GGEWVFGGPL 105 Query: 105 CTTSALMYLCQGLSSNLKATLLVSYNFYTMHRGVGSQTASRRSGQVLGVVLTVWAASLLL 164 CT + C + + T++ ++ + + T R + + + L +WAAS +L Sbjct: 106 CTIITSLDTCNQFACSAIMTVMSVDRYFALVQPF-RLTRWRTRYKTIRINLGLWAASFIL 164 Query: 165 SALPLCGWGAFVRTPWG---CLVDCSSS-----YVLFLSI 196 ALP+ + ++ G C D +S Y L+L+I Sbjct: 165 -ALPVWVYSKVIKFKDGVESCAFDLTSPDDVLWYTLYLTI 203 >gi|28557751 olfactory receptor, family 2, subfamily L, member 13 [Homo sapiens] Length = 312 Score = 38.5 bits (88), Expect = 0.022 Identities = 35/122 (28%), Positives = 55/122 (45%), Gaps = 8/122 (6%) Query: 17 KENHNSTDL----LNPPGTLNIYLFCLTCLMTFAALVGSIYSLISLLKMQNR--TVVSML 70 K NH S D L PP I+L CL L+ F A VG+ ++I L+ + R T + L Sbjct: 3 KWNHTSNDFILLGLLPPNQTGIFLLCLIILIFFLASVGN-SAMIHLIHVDPRLHTPMYFL 61 Query: 71 VASWSVDDLMSVLSVTIFMFLQWPNEVPGYFQFLCTTSALMYLCQGLSSNLKATLLVSYN 130 ++ S+ DLM + + M + + G C + +L S L T + +Y+ Sbjct: 62 LSQLSLMDLMYISTTVPKMAYNFLSGQKGISFLGCGVQSFFFLTMACSEGLLLTSM-AYD 120 Query: 131 FY 132 Y Sbjct: 121 RY 122 >gi|4503459 sphingosine-1-phosphate receptor 4 precursor [Homo sapiens] Length = 384 Score = 38.1 bits (87), Expect = 0.029 Identities = 28/81 (34%), Positives = 39/81 (48%), Gaps = 5/81 (6%) Query: 131 FYTMHRGVGSQTASRRSGQVLGVVLTVWAASLLLSALPLCGWG---AFVRTPWGCLVDCS 187 F TM R V A++ S +V G + W + LL LPL GW AF R L S Sbjct: 144 FATMVRPVAESGATKTS-RVYGFIGLCWLLAALLGMLPLLGWNCLCAFDRCS-SLLPLYS 201 Query: 188 SSYVLFLSIVYALAFGLLVGL 208 Y+LF +++A ++GL Sbjct: 202 KRYILFCLVIFAGVLATIMGL 222 >gi|116284382 G protein-coupled bile acid receptor 1 [Homo sapiens] Length = 330 Score = 37.7 bits (86), Expect = 0.038 Identities = 40/146 (27%), Positives = 60/146 (41%), Gaps = 23/146 (15%) Query: 93 WPNEVPGYFQFLCTTSALMYLCQGLSS-NLKATLLVSYNFYTMHRGVGSQTASRRSGQVL 151 W GY+ L L+YL S +L A LL+ + R + + G + Sbjct: 75 WNQSRRGYWSCL-----LVYLAPNFSFLSLLANLLLVHG----ERYMAVLRPLQPPGSIR 125 Query: 152 GVVLTVWAASLLLSALPLCGWGAFVRTPWGCLVDCSSSYVLFLSIVYALAFGLL---VGL 208 +L WA LL ++LP GW W +CSS + +Y +GLL VG Sbjct: 126 LALLLTWAGPLLFASLPALGW-----NHWTPGANCSSQAIFPAPYLYLEVYGLLLPAVGA 180 Query: 209 SVPLTHRLLCSEEPPRLHSNYQEISR 234 + L+ R+L + H Q+I R Sbjct: 181 AAFLSVRVLAT-----AHRQLQDICR 201 >gi|116284384 G protein-coupled bile acid receptor 1 [Homo sapiens] Length = 330 Score = 37.7 bits (86), Expect = 0.038 Identities = 40/146 (27%), Positives = 60/146 (41%), Gaps = 23/146 (15%) Query: 93 WPNEVPGYFQFLCTTSALMYLCQGLSS-NLKATLLVSYNFYTMHRGVGSQTASRRSGQVL 151 W GY+ L L+YL S +L A LL+ + R + + G + Sbjct: 75 WNQSRRGYWSCL-----LVYLAPNFSFLSLLANLLLVHG----ERYMAVLRPLQPPGSIR 125 Query: 152 GVVLTVWAASLLLSALPLCGWGAFVRTPWGCLVDCSSSYVLFLSIVYALAFGLL---VGL 208 +L WA LL ++LP GW W +CSS + +Y +GLL VG Sbjct: 126 LALLLTWAGPLLFASLPALGW-----NHWTPGANCSSQAIFPAPYLYLEVYGLLLPAVGA 180 Query: 209 SVPLTHRLLCSEEPPRLHSNYQEISR 234 + L+ R+L + H Q+I R Sbjct: 181 AAFLSVRVLAT-----AHRQLQDICR 201 >gi|24850109 G protein-coupled bile acid receptor 1 [Homo sapiens] Length = 330 Score = 37.7 bits (86), Expect = 0.038 Identities = 40/146 (27%), Positives = 60/146 (41%), Gaps = 23/146 (15%) Query: 93 WPNEVPGYFQFLCTTSALMYLCQGLSS-NLKATLLVSYNFYTMHRGVGSQTASRRSGQVL 151 W GY+ L L+YL S +L A LL+ + R + + G + Sbjct: 75 WNQSRRGYWSCL-----LVYLAPNFSFLSLLANLLLVHG----ERYMAVLRPLQPPGSIR 125 Query: 152 GVVLTVWAASLLLSALPLCGWGAFVRTPWGCLVDCSSSYVLFLSIVYALAFGLL---VGL 208 +L WA LL ++LP GW W +CSS + +Y +GLL VG Sbjct: 126 LALLLTWAGPLLFASLPALGW-----NHWTPGANCSSQAIFPAPYLYLEVYGLLLPAVGA 180 Query: 209 SVPLTHRLLCSEEPPRLHSNYQEISR 234 + L+ R+L + H Q+I R Sbjct: 181 AAFLSVRVLAT-----AHRQLQDICR 201 >gi|4507381 thromboxane A2 receptor [Homo sapiens] Length = 343 Score = 37.0 bits (84), Expect = 0.065 Identities = 33/111 (29%), Positives = 54/111 (48%), Gaps = 8/111 (7%) Query: 104 LCTTSALMYLCQGLSSNLKATLLVSYNFYTMHRGVG--SQTASRRSGQVLGVVLTVWAAS 161 LC ++ + GLS L + S + + R + + RR+ +G+V WAA+ Sbjct: 104 LCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLV---WAAA 160 Query: 162 LLLSALPLCGWGAF-VRTP--WGCLVDCSSSYVLFLSIVYALAFGLLVGLS 209 L L LPL G G + V+ P W L + S + +++++ GL VGLS Sbjct: 161 LALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLFSMLGGLSVGLS 211 >gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens] Length = 455 Score = 36.6 bits (83), Expect = 0.085 Identities = 52/206 (25%), Positives = 87/206 (42%), Gaps = 55/206 (26%) Query: 21 NSTDLLNPPGTLNIYLFCLTCL----MTFAALVGSIYSLISLLKMQN-RTVVSMLVASWS 75 +S++ PP +NI L + + ++G+I ++S+ ++ +V + + + Sbjct: 10 DSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLA 69 Query: 76 VDDLMSVLSVTIFMFLQWPNEVPGYFQF-------------LCTTSALMYLCQ------- 115 V DL+ +V F + EV GY+ F LC T+++M LC Sbjct: 70 VADLLLTSTVLPFSAIF---EVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYI 126 Query: 116 GLSSNLKATLLVSYNFYTMHRGVGSQTASRRSGQVLGVVLTVWAASLLLSALPLCGWGAF 175 G+S L+ +V T RG L +L VWA SL++S PL GW Sbjct: 127 GVSYPLRYPTIV-----TQRRG-------------LMALLCVWALSLVISIGPLFGW--- 165 Query: 176 VRTPWG-----CLVDCSSSYVLFLSI 196 R P C ++ YVLF ++ Sbjct: 166 -RQPAPEDETICQINEEPGYVLFSAL 190 >gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens] Length = 466 Score = 36.6 bits (83), Expect = 0.085 Identities = 52/206 (25%), Positives = 87/206 (42%), Gaps = 55/206 (26%) Query: 21 NSTDLLNPPGTLNIYLFCLTCL----MTFAALVGSIYSLISLLKMQN-RTVVSMLVASWS 75 +S++ PP +NI L + + ++G+I ++S+ ++ +V + + + Sbjct: 10 DSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLA 69 Query: 76 VDDLMSVLSVTIFMFLQWPNEVPGYFQF-------------LCTTSALMYLCQ------- 115 V DL+ +V F + EV GY+ F LC T+++M LC Sbjct: 70 VADLLLTSTVLPFSAIF---EVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYI 126 Query: 116 GLSSNLKATLLVSYNFYTMHRGVGSQTASRRSGQVLGVVLTVWAASLLLSALPLCGWGAF 175 G+S L+ +V T RG L +L VWA SL++S PL GW Sbjct: 127 GVSYPLRYPTIV-----TQRRG-------------LMALLCVWALSLVISIGPLFGW--- 165 Query: 176 VRTPWG-----CLVDCSSSYVLFLSI 196 R P C ++ YVLF ++ Sbjct: 166 -RQPAPEDETICQINEEPGYVLFSAL 190 >gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens] Length = 475 Score = 36.6 bits (83), Expect = 0.085 Identities = 52/206 (25%), Positives = 87/206 (42%), Gaps = 55/206 (26%) Query: 21 NSTDLLNPPGTLNIYLFCLTCL----MTFAALVGSIYSLISLLKMQN-RTVVSMLVASWS 75 +S++ PP +NI L + + ++G+I ++S+ ++ +V + + + Sbjct: 10 DSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLA 69 Query: 76 VDDLMSVLSVTIFMFLQWPNEVPGYFQF-------------LCTTSALMYLCQ------- 115 V DL+ +V F + EV GY+ F LC T+++M LC Sbjct: 70 VADLLLTSTVLPFSAIF---EVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYI 126 Query: 116 GLSSNLKATLLVSYNFYTMHRGVGSQTASRRSGQVLGVVLTVWAASLLLSALPLCGWGAF 175 G+S L+ +V T RG L +L VWA SL++S PL GW Sbjct: 127 GVSYPLRYPTIV-----TQRRG-------------LMALLCVWALSLVISIGPLFGW--- 165 Query: 176 VRTPWG-----CLVDCSSSYVLFLSI 196 R P C ++ YVLF ++ Sbjct: 166 -RQPAPEDETICQINEEPGYVLFSAL 190 >gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens] Length = 429 Score = 36.6 bits (83), Expect = 0.085 Identities = 52/206 (25%), Positives = 87/206 (42%), Gaps = 55/206 (26%) Query: 21 NSTDLLNPPGTLNIYLFCLTCL----MTFAALVGSIYSLISLLKMQN-RTVVSMLVASWS 75 +S++ PP +NI L + + ++G+I ++S+ ++ +V + + + Sbjct: 10 DSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLA 69 Query: 76 VDDLMSVLSVTIFMFLQWPNEVPGYFQF-------------LCTTSALMYLCQ------- 115 V DL+ +V F + EV GY+ F LC T+++M LC Sbjct: 70 VADLLLTSTVLPFSAIF---EVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYI 126 Query: 116 GLSSNLKATLLVSYNFYTMHRGVGSQTASRRSGQVLGVVLTVWAASLLLSALPLCGWGAF 175 G+S L+ +V T RG L +L VWA SL++S PL GW Sbjct: 127 GVSYPLRYPTIV-----TQRRG-------------LMALLCVWALSLVISIGPLFGW--- 165 Query: 176 VRTPWG-----CLVDCSSSYVLFLSI 196 R P C ++ YVLF ++ Sbjct: 166 -RQPAPEDETICQINEEPGYVLFSAL 190 >gi|4557265 beta-1-adrenergic receptor [Homo sapiens] Length = 477 Score = 36.6 bits (83), Expect = 0.085 Identities = 68/311 (21%), Positives = 124/311 (39%), Gaps = 43/311 (13%) Query: 39 LTCLMTFAALVGSIYSLISLLKMQN-RTVVSMLVASWSVDDLMSVLSV-----TIFMFLQ 92 L L+ + G++ ++++ K +T+ ++ + S + DL+ L V TI ++ + Sbjct: 64 LMALIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVWGR 123 Query: 93 WPNEVPGYFQFLCTT-SALMYLCQGLSSNLKATLLVSYNFYTMHRGVGSQTASRRSGQVL 151 W Y F C +++ LC ++++++ +++ + Y + + Sbjct: 124 WE-----YGSFFCELWTSVDVLC--VTASIETLCVIALDRYLAITSPFRYQSLLTRARAR 176 Query: 152 GVVLTVWAASLLLSALPLC--GWGA-------FVRTPWGCLVDCSSSYVLFLSIVYALAF 202 G+V TVWA S L+S LP+ W A P C + +Y + S+V + Sbjct: 177 GLVCTVWAISALVSFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVV-SFYV 235 Query: 203 GLLVGLSVPLTHRLLCSEEPPRLHSNYQEISRGASIPGTPPTAGRVVSLSPEDAPGPSLR 262 L + V L ++ ++ S + G + P +P S SP AP P Sbjct: 236 PLCIMAFVYLRVFREAQKQVKKIDSCERRFLGGPARPPSP-------SPSPVPAPAPP-- 286 Query: 263 RSGGCSPSSDTVFGPGAPAAAGAEACRRENRGTLYGTRSFTVSVAQKRFALILALTKVVL 322 P AP A G RR +R L R A K +I+ + + Sbjct: 287 ----PGPPRPAAAAATAPLANGRAGKRRPSR--LVALRE---QKALKTLGIIMGVF-TLC 336 Query: 323 WLPMMMHMVVQ 333 WLP + VV+ Sbjct: 337 WLPFFLANVVK 347 >gi|13540517 endothelial differentiation, sphingolipid G-protein-coupled receptor, 8 [Homo sapiens] Length = 398 Score = 35.4 bits (80), Expect = 0.19 Identities = 55/223 (24%), Positives = 89/223 (39%), Gaps = 44/223 (19%) Query: 39 LTCLMTFAALVGSIYSLISLLKMQNRTVVSM--LVASWSVDDLMSVLSVTIFMFLQWPNE 96 + CL A +V +++ +L R M L+ S ++ DL++ + + L P Sbjct: 41 VVCLAVCAFIVLENLAVLLVLGRHPRFHAPMFLLLGSLTLSDLLAGAAYAANILLSGPLT 100 Query: 97 VPGYFQFLCTTSALMYLCQG-----LSSNLKATLLVSYN-FYTMHRGVGSQTASRRSGQV 150 L + AL + +G L++++ + L ++ TM R + +SR G+ Sbjct: 101 -------LKLSPALWFAREGGVFVALTASVLSLLAIALERSLTMARRGPAPVSSR--GRT 151 Query: 151 LGVVLTVWAASLLLSALPLCGWGAFVRTPWGCLVDCSS-------SYVLFLSIVYALAFG 203 L + W SLLL LP GW G L CS+ +YVLF LAF Sbjct: 152 LAMAAAAWGVSLLLGLLPALGWNCL-----GRLDACSTVLPLYAKAYVLFC----VLAFV 202 Query: 204 LLVGLSVPLTHRLLCSEEPPRLHSNYQEISRGASIPGTPPTAG 246 ++ L R+ C Q + +P P TAG Sbjct: 203 GILAAICALYARIYC-----------QVRANARRLPARPGTAG 234 >gi|9951913 G protein-coupled receptor 162 isoform 2 [Homo sapiens] Length = 588 Score = 35.0 bits (79), Expect = 0.25 Identities = 31/131 (23%), Positives = 56/131 (42%), Gaps = 6/131 (4%) Query: 47 ALVGSIYSLISL-LKMQNRTVVSMLVASWS-VDDLMSVLSVTIFMFLQWPNEVPGYFQF- 103 AL+ + + ++S+ K Q + +L+ + LM+ + +T F +Q + + + Sbjct: 27 ALLANAWIILSISAKQQKHKPLELLLCFLAGTHILMAAVPLTTFAVVQLRRQASSDYDWN 86 Query: 104 --LCTTSALMYLCQGLSSNLKATLLVSYNFYTMHRGVGSQTASRRSGQVLGVVLTVWAAS 161 +C Y L++ L SY+ M R + S Q L V+ +W S Sbjct: 87 ESICKVFVSTYYTLALATCFTVASL-SYHRMWMVRWPVNYRLSNAKKQALHAVMGIWMVS 145 Query: 162 LLLSALPLCGW 172 +LS LP GW Sbjct: 146 FILSTLPSIGW 156 >gi|55956923 5-hydroxytryptamine (serotonin) receptor 1A [Homo sapiens] Length = 422 Score = 34.7 bits (78), Expect = 0.32 Identities = 42/184 (22%), Positives = 80/184 (43%), Gaps = 26/184 (14%) Query: 7 NLSTNDSSLWKENHNSTDLLNPPGTLNIYLFCLTCLMTFAALVGSIYSLISL-LKMQNRT 65 N +T+ + ++ N+T + + + + L + F A++G+ + ++ L+ + Sbjct: 10 NNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQN 69 Query: 66 VVSMLVASWSVDDLM-SVLSVTIFMFLQWPN---------EVPGYFQFLCTTSALMYLCQ 115 V + L+ S +V DLM SVL + + Q N ++ LC TS++++LC Sbjct: 70 VANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLC- 128 Query: 116 GLSSNLKATLLVSYNFYTMHRGVGSQTASRRSGQVLGVVLTVWAASLLLSALPLCGWGAF 175 A L Y T ++ RR+ ++ + W L+S P+ GW Sbjct: 129 -------AIALDRYWAITDPIDYVNKRTPRRAAALISL---TWLIGFLISIPPMLGW--- 175 Query: 176 VRTP 179 RTP Sbjct: 176 -RTP 178 >gi|6912348 lysophosphatidic acid receptor 3 [Homo sapiens] Length = 353 Score = 34.7 bits (78), Expect = 0.32 Identities = 49/206 (23%), Positives = 85/206 (41%), Gaps = 35/206 (16%) Query: 19 NHNSTDLLNP-PGTLNIYLFCLTCLMTFAALVGSIYSLISLLKMQNRTV---VSMLVASW 74 N ++TD ++ GT + + C+ F + SL+ ++NR L+A+ Sbjct: 15 NRSNTDTVDDWTGTKLVIVLCVGTF--FCLFIFFSNSLVIAAVIKNRKFHFPFYYLLANL 72 Query: 75 SVDDLMSVLSVTIFMFLQWPNEVPGYFQFLCTTSALMYLCQGL-SSNLKATLL------V 127 + D + ++ MF P T +L QGL S+L A+L V Sbjct: 73 AAADFFAGIAYVFLMFNTGPVSKT-------LTVNRWFLRQGLLDSSLTASLTNLLVIAV 125 Query: 128 SYNFYTMHRGVGSQTASRRSGQVLGVVLTVWAASLLLSALPLCGWGAFVRTPWGCLVDCS 187 + M V S +R V ++L VWA ++ + A+P GW + CS Sbjct: 126 ERHMSIMRMRVHSNLTKKR---VTLLILLVWAIAIFMGAVPTLGWNCLCN-----ISACS 177 Query: 188 S-------SYVLFLSIVYALAFGLLV 206 S SY++F ++ +AF ++V Sbjct: 178 SLAPIYSRSYLVFWTVSNLMAFLIMV 203 >gi|4885325 G protein-coupled receptor 3 [Homo sapiens] Length = 330 Score = 34.3 bits (77), Expect = 0.42 Identities = 36/165 (21%), Positives = 76/165 (46%), Gaps = 25/165 (15%) Query: 64 RTVVSMLVASWSVDDLMSVLSVTIFMFLQWPNEVPGYFQFLCTTSALM------YLCQGL 117 R + +LV S +V DL++ L + + + C SA M L Sbjct: 72 RAPMFLLVGSLAVADLLAGLGLVLH-----------FAAVFCIGSAEMSLVLVGVLAMAF 120 Query: 118 SSNLKATLLVSYNFY-TMHRGVG--SQTASRRSGQVLGVVLTVWAASLLLSALPLCGWGA 174 ++++ + L ++ + Y +++ + S+T R+ +L +V W +L L LP+ W Sbjct: 121 TASIGSLLAITVDRYLSLYNALTYYSETTVTRTYVMLALV---WGGALGLGLLPVLAWNC 177 Query: 175 F-VRTPWGCLVDCSSSYVLFLSIVYALAFGLLVGLSVPLTHRLLC 218 T G + S ++++ L+I + + FG+++ L + R++C Sbjct: 178 LDGLTTCGVVYPLSKNHLVVLAIAFFMVFGIMLQLYAQIC-RIVC 221 >gi|126362971 serine/threonine kinase 10 [Homo sapiens] Length = 968 Score = 33.9 bits (76), Expect = 0.55 Identities = 23/77 (29%), Positives = 37/77 (48%), Gaps = 3/77 (3%) Query: 626 DNEEALDTVSIISNISQSSTQVRSPSLRYSRKENRFVSCDLGETASY-SLFLPTSNPDGD 684 + E+A+D S + N +Q+S++V PSL + S L + S S+ P S P GD Sbjct: 326 EEEDAVDAASTLENHTQNSSEVSPPSLNADKPLEESPSTPLAPSQSQDSVNEPCSQPSGD 385 Query: 685 --INISIPDTVEAHRQN 699 + + P V +N Sbjct: 386 RSLQTTSPPVVAPGNEN 402 >gi|122937311 solute carrier family 35, member F4 [Homo sapiens] Length = 521 Score = 33.9 bits (76), Expect = 0.55 Identities = 17/48 (35%), Positives = 24/48 (50%), Gaps = 9/48 (18%) Query: 172 WGAFVRTPWGCLVDCSSSYVLFLSIVYALAFGLLVGLSVPLTHRLLCS 219 W +F PWGCL + + LAF +LV + V LT+ +L S Sbjct: 392 WSSFAALPWGCLCGMAGLW---------LAFNILVNVGVVLTYPILIS 430 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.131 0.388 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 28,592,374 Number of Sequences: 37866 Number of extensions: 1347934 Number of successful extensions: 5342 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 13 Number of HSP's successfully gapped in prelim test: 88 Number of HSP's that attempted gapping in prelim test: 5268 Number of HSP's gapped (non-prelim): 168 length of query: 731 length of database: 18,247,518 effective HSP length: 110 effective length of query: 621 effective length of database: 14,082,258 effective search space: 8745082218 effective search space used: 8745082218 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.