Guide to the Human Genome
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Name: HTR1A Sequence: fasta or formatted (422aa) NCBI GI: 55956923
Description:

5-hydroxytryptamine (serotonin) receptor 1A

Referenced in:

Serotonin

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             9.7         41           3
 C cysteine            3.3         14           2
 D aspartate           3.8         16           2
 E glutamate           3.6         15           1
 F phenylalanine       4.0         17           2
 G glycine             7.1         30           2
 H histidine           1.4          6           1
 I isoleucine          6.9         29           2
 K lysine              5.0         21           2
 L leucine            11.4         48           3
 M methionine          1.9          8           1
 N asparagine          4.5         19           2
 P proline             5.7         24           2
 Q glutamine           2.1          9           1
 R arginine            5.5         23           2
 S serine              6.4         27           2
 T threonine           6.4         27           2
 V valine              6.9         29           2
 W tryptophan          1.7          7           1
 Y tyrosine            2.8         12           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   5-hydroxytryptamine (serotonin) receptor 1A 
HTR1B                 0.328   5-hydroxytryptamine (serotonin) receptor 1B 
HTR1D                 0.317   5-hydroxytryptamine (serotonin) receptor 1D 
HTR1F                 0.290   5-hydroxytryptamine (serotonin) receptor 1F 
HTR1E                 0.269   5-hydroxytryptamine (serotonin) receptor 1E 
ADRA2C                0.263   alpha-2C-adrenergic receptor 
ADRA1B                0.245   alpha-1B-adrenergic receptor 
HTR7                  0.240   5-hydroxytryptamine receptor 7 isoform b 
HTR7                  0.240   5-hydroxytryptamine receptor 7 isoform d 
HTR7                  0.240   5-hydroxytryptamine receptor 7 isoform a 
ADRA1D                0.234   alpha-1D-adrenergic receptor 
DRD2                  0.228   dopamine receptor D2 isoform short 
ADRA2B                0.224   alpha-2B-adrenergic receptor 
ADRA2A                0.223   alpha-2A-adrenergic receptor 
DRD3                  0.222   dopamine receptor D3 isoform a 
DRD2                  0.222   dopamine receptor D2 isoform long 
DRD3                  0.215   dopamine receptor D3 isoform e 
ADRB1                 0.210   beta-1-adrenergic receptor 
HTR5A                 0.207   5-hydroxytryptamine receptor 5A 
DRD4                  0.204   dopamine receptor D4 
CHRM1                 0.185   cholinergic receptor, muscarinic 1 
CHRM2                 0.179   cholinergic receptor, muscarinic 2 
CHRM2                 0.179   cholinergic receptor, muscarinic 2 
CHRM2                 0.179   cholinergic receptor, muscarinic 2 
CHRM2                 0.179   cholinergic receptor, muscarinic 2 
CHRM2                 0.179   cholinergic receptor, muscarinic 2 
CHRM2                 0.179   cholinergic receptor, muscarinic 2 
CHRM2                 0.179   cholinergic receptor, muscarinic 2 
CHRM2                 0.179   cholinergic receptor, muscarinic 2 
HTR2C                 0.179   5-hydroxytryptamine (serotonin) receptor 2C 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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