Guide to the Human Genome
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Search of human proteins with 82734223

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|82734223 beta-defensin 124 [Homo sapiens]
         (71 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|82734223 beta-defensin 124 [Homo sapiens]                          157   1e-39
gi|116517226 beta-defensin 135 [Homo sapiens]                          49   1e-06
gi|23503331 defensin, beta 123 precursor [Homo sapiens]                41   2e-04
gi|58865339 defensin, beta 121 [Homo sapiens]                          40   3e-04
gi|21040279 defensin, beta 127 preproprotein [Homo sapiens]            40   4e-04
gi|76563936 defensin, beta 125 preproprotein [Homo sapiens]            40   5e-04
gi|46409558 beta-defensin 32 precursor [Homo sapiens]                  38   0.001
gi|16905373 beta-defensin 118 [Homo sapiens]                           38   0.002
gi|37704382 defensin, beta 119 isoform a precursor [Homo sapiens]      36   0.006
gi|103485139 defensin, beta 104A precursor [Homo sapiens]              35   0.017
gi|103485137 defensin, beta 104B precursor [Homo sapiens]              35   0.017
gi|50344744 beta-defensin 108B [Homo sapiens]                          34   0.028
gi|239753808 PREDICTED: hypothetical protein [Homo sapiens]            33   0.037
gi|239748372 PREDICTED: hypothetical protein [Homo sapiens]            33   0.037
gi|169166494 PREDICTED: hypothetical protein [Homo sapiens]            33   0.037
gi|83582798 beta-defensin 115 [Homo sapiens]                           33   0.048
gi|239749357 PREDICTED: hypothetical protein XP_002347009 [Homo ...    33   0.063
gi|83582800 beta-defensin 116 [Homo sapiens]                           33   0.063
gi|83582802 beta-defensin 128 [Homo sapiens]                           33   0.063
gi|4506107 prolactin receptor [Homo sapiens]                           31   0.24 
gi|13624333 defensin, beta 126 preproprotein [Homo sapiens]            30   0.31 
gi|22748611 defensin, beta 106A precursor [Homo sapiens]               30   0.41 
gi|103485143 defensin, beta 106B precursor [Homo sapiens]              30   0.41 
gi|17402931 sperm associated antigen 11B isoform C preproprotein...    29   0.91 
gi|161019170 mucin 5AC [Homo sapiens]                                  28   1.2  
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]       28   1.2  
gi|83582794 beta-defensin 110 [Homo sapiens]                           28   1.6  
gi|5730021 regulatory solute carrier protein, family 1, member 1...    28   2.0  
gi|239757478 PREDICTED: defensin, beta 117 [Homo sapiens]              27   2.6  
gi|239755481 PREDICTED: similar to Putative uncharacterized prot...    27   2.6  

>gi|82734223 beta-defensin 124 [Homo sapiens]
          Length = 71

 Score =  157 bits (398), Expect = 1e-39
 Identities = 71/71 (100%), Positives = 71/71 (100%)

Query: 1  MTQLLLFLVALLVLGHVPSGRSEFKRCWKGQGACQTYCTRQETYMHLCPDASLCCLSYAL 60
          MTQLLLFLVALLVLGHVPSGRSEFKRCWKGQGACQTYCTRQETYMHLCPDASLCCLSYAL
Sbjct: 1  MTQLLLFLVALLVLGHVPSGRSEFKRCWKGQGACQTYCTRQETYMHLCPDASLCCLSYAL 60

Query: 61 KPPPVPKHEYE 71
          KPPPVPKHEYE
Sbjct: 61 KPPPVPKHEYE 71


>gi|116517226 beta-defensin 135 [Homo sapiens]
          Length = 77

 Score = 48.5 bits (114), Expect = 1e-06
 Identities = 25/62 (40%), Positives = 33/62 (53%), Gaps = 8/62 (12%)

Query: 4  LLLFLVALLVLGHVPSGRSE--------FKRCWKGQGACQTYCTRQETYMHLCPDASLCC 55
          +LL LV L +L +VP GRS         F  CW+ QG C+  C + E Y  LC    LCC
Sbjct: 6  VLLALVVLNLLFYVPPGRSGPNVYIQKIFASCWRLQGTCRPKCLKNEQYRILCDTIHLCC 65

Query: 56 LS 57
          ++
Sbjct: 66 VN 67


>gi|23503331 defensin, beta 123 precursor [Homo sapiens]
          Length = 67

 Score = 41.2 bits (95), Expect = 2e-04
 Identities = 23/70 (32%), Positives = 35/70 (50%), Gaps = 6/70 (8%)

Query: 1  MTQLLLFLVALLVLGHVPSGRSEFKRCWKGQGACQTYCTRQETYMHLCPDASLCCLSYAL 60
          M  LLL L  LL+L  +  G ++  RCW   G C+  C+++E     C +  +CC    +
Sbjct: 1  MKLLLLTLTVLLLLSQLTPGGTQ--RCWNLYGKCRYRCSKKERVYVYCINNKMCC----V 54

Query: 61 KPPPVPKHEY 70
          KP   PK  +
Sbjct: 55 KPKYQPKERW 64


>gi|58865339 defensin, beta 121 [Homo sapiens]
          Length = 76

 Score = 40.4 bits (93), Expect = 3e-04
 Identities = 20/56 (35%), Positives = 26/56 (46%), Gaps = 4/56 (7%)

Query: 1  MTQLLLFLVALLVLGHVPSGRSEFKRCWKGQGACQTYCTRQETYMHLCPDASLCCL 56
          M  LLL L   L+L  V    +   +CW   G C+T C   E Y  LC   + CC+
Sbjct: 1  MKLLLLLLTVTLLLAQV----TPVMKCWGKSGRCRTTCKESEVYYILCKTEAKCCV 52


>gi|21040279 defensin, beta 127 preproprotein [Homo sapiens]
          Length = 99

 Score = 40.0 bits (92), Expect = 4e-04
 Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 9/71 (12%)

Query: 6  LFLVALLVLGHVPSGRSEFKRCWKG--QGACQTYCTRQETYMHLCPDASLCCLSY----- 58
          LF++  ++L   P+   + K+CW    QG C+  C   E    LC +   CCL+      
Sbjct: 3  LFMIIAILLFQKPTVTEQLKKCWNNYVQGHCRKICRVNEVPEALCENGRYCCLNIKELEA 62

Query: 59 --ALKPPPVPK 67
             +  PP PK
Sbjct: 63 CKKITKPPRPK 73


>gi|76563936 defensin, beta 125 preproprotein [Homo sapiens]
          Length = 156

 Score = 39.7 bits (91), Expect = 5e-04
 Identities = 23/71 (32%), Positives = 33/71 (46%), Gaps = 8/71 (11%)

Query: 1  MTQLLLFLVALLVLGHVPSGRSEFKRCWKGQ-GACQTYCTRQETYMHLCPDASLCCLSYA 59
          M  L+L  +   +L  V  G  E ++CWK   G C+  C   E Y+ LC +   CC+S  
Sbjct: 1  MNILMLTFIICGLLTRVTKGSFEPQKCWKNNVGHCRRRCLDTERYILLCRNKLSCCIS-- 58

Query: 60 LKPPPVPKHEY 70
               +  HEY
Sbjct: 59 -----IISHEY 64


>gi|46409558 beta-defensin 32 precursor [Homo sapiens]
          Length = 95

 Score = 38.1 bits (87), Expect = 0.001
 Identities = 23/65 (35%), Positives = 31/65 (47%), Gaps = 1/65 (1%)

Query: 1  MTQLLLFLVALLVLGHVPSGRSEFKRCWKGQ-GACQTYCTRQETYMHLCPDASLCCLSYA 59
          M  LLL L AL  L  V    +   +C     G C+T C   ET + +C  +  CC+SY+
Sbjct: 1  MKFLLLVLAALGFLTQVIPASAGGSKCVSNTPGYCRTCCHWGETALFMCNASRKCCISYS 60

Query: 60 LKPPP 64
            P P
Sbjct: 61 FLPKP 65


>gi|16905373 beta-defensin 118 [Homo sapiens]
          Length = 123

 Score = 37.7 bits (86), Expect = 0.002
 Identities = 19/56 (33%), Positives = 25/56 (44%)

Query: 1  MTQLLLFLVALLVLGHVPSGRSEFKRCWKGQGACQTYCTRQETYMHLCPDASLCCL 56
          M  LLL L  L++L  V    S  K+CW   G C+  C   E     C +   CC+
Sbjct: 1  MKLLLLALPMLVLLPQVIPAYSGEKKCWNRSGHCRKQCKDGEAVKDTCKNLRACCI 56


>gi|37704382 defensin, beta 119 isoform a precursor [Homo sapiens]
          Length = 84

 Score = 36.2 bits (82), Expect = 0.006
 Identities = 20/57 (35%), Positives = 25/57 (43%), Gaps = 1/57 (1%)

Query: 1  MTQLLLFLVALLVLGH-VPSGRSEFKRCWKGQGACQTYCTRQETYMHLCPDASLCCL 56
          M  L LFL  LL +   V SG+    RC    G C+  C + E     C +   CCL
Sbjct: 1  MKLLYLFLAILLAIEEPVISGKRHILRCMGNSGICRASCKKNEQPYLYCRNCQSCCL 57


>gi|103485139 defensin, beta 104A precursor [Homo sapiens]
          Length = 72

 Score = 34.7 bits (78), Expect = 0.017
 Identities = 20/56 (35%), Positives = 29/56 (51%), Gaps = 4/56 (7%)

Query: 4  LLLFLVALLVLGHVPSGRSEFKR---CWKGQGACQTYCTRQETYMHLCPDASLCCL 56
          +LL  ++LL+   +P  RSEF+    C  G   C+  C  QE  +  CP+   CCL
Sbjct: 5  VLLLAISLLLYQDLPV-RSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCL 59


>gi|103485137 defensin, beta 104B precursor [Homo sapiens]
          Length = 72

 Score = 34.7 bits (78), Expect = 0.017
 Identities = 20/56 (35%), Positives = 29/56 (51%), Gaps = 4/56 (7%)

Query: 4  LLLFLVALLVLGHVPSGRSEFKR---CWKGQGACQTYCTRQETYMHLCPDASLCCL 56
          +LL  ++LL+   +P  RSEF+    C  G   C+  C  QE  +  CP+   CCL
Sbjct: 5  VLLLAISLLLYQDLPV-RSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCL 59


>gi|50344744 beta-defensin 108B [Homo sapiens]
          Length = 73

 Score = 33.9 bits (76), Expect = 0.028
 Identities = 17/60 (28%), Positives = 32/60 (53%), Gaps = 2/60 (3%)

Query: 4  LLLFLVALLVLGHVPSGRSEFKR-CWKGQGACQTYCTRQETYMHLCPDASLCCLSYALKP 62
          +LLF +   +   +P+ R +FK  C +  G+C+ +C   E ++  C ++  CCL    +P
Sbjct: 5  VLLFAIFFFMSQVLPA-RGKFKEICERPNGSCRDFCLETEIHVGRCLNSQPCCLPLGHQP 63


>gi|239753808 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 83

 Score = 33.5 bits (75), Expect = 0.037
 Identities = 17/60 (28%), Positives = 32/60 (53%), Gaps = 2/60 (3%)

Query: 4  LLLFLVALLVLGHVPSGRSEFKR-CWKGQGACQTYCTRQETYMHLCPDASLCCLSYALKP 62
          +LLF +   +   +P+ R +FK  C +  G+C+ +C   E ++  C ++  CCL    +P
Sbjct: 15 VLLFAIFFFMSQVLPA-RGKFKEICERPNGSCRDFCLETEIHVGRCLNSRPCCLPLGHQP 73


>gi|239748372 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 83

 Score = 33.5 bits (75), Expect = 0.037
 Identities = 17/60 (28%), Positives = 32/60 (53%), Gaps = 2/60 (3%)

Query: 4  LLLFLVALLVLGHVPSGRSEFKR-CWKGQGACQTYCTRQETYMHLCPDASLCCLSYALKP 62
          +LLF +   +   +P+ R +FK  C +  G+C+ +C   E ++  C ++  CCL    +P
Sbjct: 15 VLLFAIFFFMSQVLPA-RGKFKEICERPNGSCRDFCLETEIHVGRCLNSRPCCLPLGHQP 73


>gi|169166494 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 73

 Score = 33.5 bits (75), Expect = 0.037
 Identities = 17/60 (28%), Positives = 32/60 (53%), Gaps = 2/60 (3%)

Query: 4  LLLFLVALLVLGHVPSGRSEFKR-CWKGQGACQTYCTRQETYMHLCPDASLCCLSYALKP 62
          +LLF +   +   +P+ R +FK  C +  G+C+ +C   E ++  C ++  CCL    +P
Sbjct: 5  VLLFAIFFFMSQVLPA-RGKFKEICERPNGSCRDFCLETEIHVGRCLNSRPCCLPLGHQP 63


>gi|83582798 beta-defensin 115 [Homo sapiens]
          Length = 88

 Score = 33.1 bits (74), Expect = 0.048
 Identities = 18/53 (33%), Positives = 26/53 (49%), Gaps = 3/53 (5%)

Query: 5  LLFLVALLVLGHV-PSGRSEFKRCWKGQGACQTYCTRQETYMHLCPDASLCCL 56
          +L LV L+VL    P G    +RC+ G G C+  C   E     C +  +CC+
Sbjct: 17 VLALVVLVVLAQTAPDGW--IRRCYYGTGRCRKSCKEIERKKEKCGEKHICCV 67


>gi|239749357 PREDICTED: hypothetical protein XP_002347009 [Homo
           sapiens]
          Length = 111

 Score = 32.7 bits (73), Expect = 0.063
 Identities = 14/43 (32%), Positives = 23/43 (53%), Gaps = 1/43 (2%)

Query: 21  RSEFKR-CWKGQGACQTYCTRQETYMHLCPDASLCCLSYALKP 62
           R +FK  C +  G+CQ +C   E ++  C ++  CCL    +P
Sbjct: 59  RGKFKEICERPNGSCQDFCLETEIHVGRCLNSRPCCLPLGHQP 101


>gi|83582800 beta-defensin 116 [Homo sapiens]
          Length = 102

 Score = 32.7 bits (73), Expect = 0.063
 Identities = 19/66 (28%), Positives = 27/66 (40%), Gaps = 5/66 (7%)

Query: 1  MTQLLLFLVALLVLG-----HVPSGRSEFKRCWKGQGACQTYCTRQETYMHLCPDASLCC 55
          MT  +L ++A    G     H    R  +  C   QG C+  C   E     CP+   CC
Sbjct: 9  MTIAILMILAQKTPGGLFRSHNGKSREPWNPCELYQGMCRNACREYEIQYLTCPNDQKCC 68

Query: 56 LSYALK 61
          L  ++K
Sbjct: 69 LKLSVK 74


>gi|83582802 beta-defensin 128 [Homo sapiens]
          Length = 93

 Score = 32.7 bits (73), Expect = 0.063
 Identities = 18/51 (35%), Positives = 26/51 (50%), Gaps = 1/51 (1%)

Query: 6  LFLVALLVLGHVPSGRSEFKRCW-KGQGACQTYCTRQETYMHLCPDASLCC 55
          LFLV +++L  V +  +  K+C+ K  G C+  C   E Y   C    LCC
Sbjct: 3  LFLVLIILLFEVLTDGARLKKCFNKVTGYCRKKCKVGERYEIGCLSGKLCC 53


>gi|4506107 prolactin receptor [Homo sapiens]
          Length = 622

 Score = 30.8 bits (68), Expect = 0.24
 Identities = 24/65 (36%), Positives = 27/65 (41%), Gaps = 18/65 (27%)

Query: 4  LLLFLVALLVLGHVPSGRSE-FK---------RCWKGQGA--------CQTYCTRQETYM 45
          LLLFL   L+ G +P G+ E FK          CW   G           TY    ET M
Sbjct: 13 LLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNYSLTYHREGETLM 72

Query: 46 HLCPD 50
          H CPD
Sbjct: 73 HECPD 77


>gi|13624333 defensin, beta 126 preproprotein [Homo sapiens]
          Length = 111

 Score = 30.4 bits (67), Expect = 0.31
 Identities = 16/60 (26%), Positives = 26/60 (43%), Gaps = 4/60 (6%)

Query: 1  MTQLLLFLVALLVLGHVPSGRSEFKRCWKGQGACQTYCTRQETYMH----LCPDASLCCL 56
          M  LL  L   ++L  + SG    K+C    G C+  C  +E ++     +C     CC+
Sbjct: 1  MKSLLFTLAVFMLLAQLVSGNWYVKKCLNDVGICKKKCKPEEMHVKNGWAMCGKQRDCCV 60


>gi|22748611 defensin, beta 106A precursor [Homo sapiens]
          Length = 65

 Score = 30.0 bits (66), Expect = 0.41
 Identities = 15/51 (29%), Positives = 25/51 (49%), Gaps = 2/51 (3%)

Query: 7  FLVALLVLGHVPSGRSEF--KRCWKGQGACQTYCTRQETYMHLCPDASLCC 55
          FL    VL  +   ++ F  ++C K +G C+  C + E  + LC  +  CC
Sbjct: 4  FLFLFAVLFFLTPAKNAFFDEKCNKLKGTCKNNCGKNEELIALCQKSLKCC 54


>gi|103485143 defensin, beta 106B precursor [Homo sapiens]
          Length = 65

 Score = 30.0 bits (66), Expect = 0.41
 Identities = 15/51 (29%), Positives = 25/51 (49%), Gaps = 2/51 (3%)

Query: 7  FLVALLVLGHVPSGRSEF--KRCWKGQGACQTYCTRQETYMHLCPDASLCC 55
          FL    VL  +   ++ F  ++C K +G C+  C + E  + LC  +  CC
Sbjct: 4  FLFLFAVLFFLTPAKNAFFDEKCNKLKGTCKNNCGKNEELIALCQKSLKCC 54


>gi|17402931 sperm associated antigen 11B isoform C preproprotein
           [Homo sapiens]
          Length = 113

 Score = 28.9 bits (63), Expect = 0.91
 Identities = 12/31 (38%), Positives = 15/31 (48%), Gaps = 1/31 (3%)

Query: 27  CWKGQGACQTYCTRQETYMHLC-PDASLCCL 56
           C + +G CQ YC   ET +  C      CCL
Sbjct: 82  CRRSEGFCQEYCNYMETQVGYCSKKKDACCL 112


>gi|161019170 mucin 5AC [Homo sapiens]
          Length = 6207

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 10/23 (43%), Positives = 12/23 (52%)

Query: 32   GACQTYCTRQETYMHLCPDASLC 54
            G C+ +CT    Y   C DA LC
Sbjct: 1813 GDCECFCTAVAAYAQACHDAGLC 1835


>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
          Length = 5765

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 10/23 (43%), Positives = 12/23 (52%)

Query: 32   GACQTYCTRQETYMHLCPDASLC 54
            G C+ +CT    Y   C DA LC
Sbjct: 1123 GDCECFCTAVAAYAQACHDAGLC 1145


>gi|83582794 beta-defensin 110 [Homo sapiens]
          Length = 62

 Score = 28.1 bits (61), Expect = 1.6
 Identities = 17/54 (31%), Positives = 26/54 (48%), Gaps = 1/54 (1%)

Query: 4  LLLFLVALLVLGHVPSGRSEFKRCWKGQGACQTYCTRQE-TYMHLCPDASLCCL 56
          +L F V +L        +  F+RC K +G C+T+C   E  Y +     S CC+
Sbjct: 9  ILHFWVTILPARSNFEPKYRFERCEKVRGICKTFCDDVEYDYGYCIKWRSQCCV 62


>gi|5730021 regulatory solute carrier protein, family 1, member 1
           [Homo sapiens]
          Length = 617

 Score = 27.7 bits (60), Expect = 2.0
 Identities = 15/34 (44%), Positives = 19/34 (55%), Gaps = 2/34 (5%)

Query: 30  GQGACQTYCTRQETYMHLCPDASLCCLSYALKPP 63
           GQG   +   R ET  ++CPDAS   L Y  +PP
Sbjct: 525 GQGIQNSVTDRPETRENVCPDASRPLLEY--EPP 556


>gi|239757478 PREDICTED: defensin, beta 117 [Homo sapiens]
          Length = 53

 Score = 27.3 bits (59), Expect = 2.6
 Identities = 10/32 (31%), Positives = 14/32 (43%)

Query: 25 KRCWKGQGACQTYCTRQETYMHLCPDASLCCL 56
          K CW  +G C+  C   E     C +   CC+
Sbjct: 16 KSCWIIKGHCRKNCKPGEQVKKPCKNGDYCCI 47


>gi|239755481 PREDICTED: similar to Putative uncharacterized protein
           ENSP00000334305 [Homo sapiens]
          Length = 771

 Score = 27.3 bits (59), Expect = 2.6
 Identities = 15/36 (41%), Positives = 17/36 (47%), Gaps = 2/36 (5%)

Query: 30  GQGACQTYCTRQETYMHLCPDASLCCLSYALKPPPV 65
           G  AC   C R+    H CPD SL   S   + PPV
Sbjct: 405 GTQACFEVCARRLKLAHFCPDTSL--WSCGGQSPPV 438


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.139    0.478 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,555,786
Number of Sequences: 37866
Number of extensions: 141252
Number of successful extensions: 490
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 452
Number of HSP's gapped (non-prelim): 45
length of query: 71
length of database: 18,247,518
effective HSP length: 44
effective length of query: 27
effective length of database: 16,581,414
effective search space: 447698178
effective search space used: 447698178
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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