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Search of human proteins with 7710121
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7710121 engrailed homeobox 2 [Homo sapiens]
(333 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7710121 engrailed homeobox 2 [Homo sapiens] 686 0.0
gi|126090909 engrailed homeobox 1 [Homo sapiens] 277 1e-74
gi|89257348 homeo box HB9 [Homo sapiens] 91 1e-18
gi|24497517 homeobox A5 [Homo sapiens] 88 1e-17
gi|239742243 PREDICTED: HPX-153 homeobox [Homo sapiens] 87 3e-17
gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens] 86 4e-17
gi|23397672 homeobox D4 [Homo sapiens] 85 1e-16
gi|5031757 T-cell leukemia homeobox 1 [Homo sapiens] 85 1e-16
gi|7110735 ventral anterior homeobox 2 [Homo sapiens] 82 7e-16
gi|94536800 empty spiracles homolog 1 [Homo sapiens] 78 1e-14
gi|19923391 homeobox D3 [Homo sapiens] 77 2e-14
gi|149588930 gastrulation brain homeo box 1 [Homo sapiens] 77 3e-14
gi|23510368 homeobox D11 [Homo sapiens] 76 4e-14
gi|162951873 ventral anterior homeobox 1 isoform a [Homo sapiens] 76 5e-14
gi|194363768 homeobox D9 [Homo sapiens] 75 8e-14
gi|118582284 msh homeobox 1 [Homo sapiens] 74 2e-13
gi|24497526 homeobox B1 [Homo sapiens] 74 2e-13
gi|84105335 mesenchyme homeobox 2 [Homo sapiens] 73 3e-13
gi|148613882 homeobox A4 [Homo sapiens] 73 3e-13
gi|4503615 even-skipped homeobox 1 [Homo sapiens] 73 4e-13
gi|182765442 homeobox A10 isoform a [Homo sapiens] 72 5e-13
gi|20143960 distal-less homeobox 4 isoform b [Homo sapiens] 72 5e-13
gi|24497538 homeobox C4 [Homo sapiens] 72 9e-13
gi|24497540 homeobox C4 [Homo sapiens] 72 9e-13
gi|239748344 PREDICTED: NK1 homeobox 1 [Homo sapiens] 72 9e-13
gi|13273315 homeobox B4 [Homo sapiens] 72 9e-13
gi|20143962 distal-less homeobox 4 isoform a [Homo sapiens] 71 1e-12
gi|226437602 NK1 homeobox 2 [Homo sapiens] 71 2e-12
gi|91208415 mesenchyme homeobox 1 isoform 3 [Homo sapiens] 71 2e-12
gi|4758710 mesenchyme homeobox 1 isoform 1 [Homo sapiens] 71 2e-12
>gi|7710121 engrailed homeobox 2 [Homo sapiens]
Length = 333
Score = 686 bits (1770), Expect = 0.0
Identities = 333/333 (100%), Positives = 333/333 (100%)
Query: 1 MEENDPKPGEAAAAVEGQRQPESSPGGGSGGGGGSSPGEADTGRRRALMLPAVLQAPGNH 60
MEENDPKPGEAAAAVEGQRQPESSPGGGSGGGGGSSPGEADTGRRRALMLPAVLQAPGNH
Sbjct: 1 MEENDPKPGEAAAAVEGQRQPESSPGGGSGGGGGSSPGEADTGRRRALMLPAVLQAPGNH 60
Query: 61 QHPHRITNFFIDNILRPEFGRRKDAGTCCAGAGGGRGGGAGGEGGASGAEGGGGAGGSEQ 120
QHPHRITNFFIDNILRPEFGRRKDAGTCCAGAGGGRGGGAGGEGGASGAEGGGGAGGSEQ
Sbjct: 61 QHPHRITNFFIDNILRPEFGRRKDAGTCCAGAGGGRGGGAGGEGGASGAEGGGGAGGSEQ 120
Query: 121 LLGSGSREPRQNPPCAPGAGGPLPAAGSDSPGDGEGGSKTLSLHGGAKKGGDPGGPLDGS 180
LLGSGSREPRQNPPCAPGAGGPLPAAGSDSPGDGEGGSKTLSLHGGAKKGGDPGGPLDGS
Sbjct: 121 LLGSGSREPRQNPPCAPGAGGPLPAAGSDSPGDGEGGSKTLSLHGGAKKGGDPGGPLDGS 180
Query: 181 LKARGLGGGDLSVSSDSDSSQAGANLGAQPMLWPAWVYCTRYSDRPSSGPRSRKPKKKNP 240
LKARGLGGGDLSVSSDSDSSQAGANLGAQPMLWPAWVYCTRYSDRPSSGPRSRKPKKKNP
Sbjct: 181 LKARGLGGGDLSVSSDSDSSQAGANLGAQPMLWPAWVYCTRYSDRPSSGPRSRKPKKKNP 240
Query: 241 NKEDKRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKIK 300
NKEDKRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKIK
Sbjct: 241 NKEDKRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKIK 300
Query: 301 KATGNKNTLAVHLMAQGLYNHSTTAKEGKSDSE 333
KATGNKNTLAVHLMAQGLYNHSTTAKEGKSDSE
Sbjct: 301 KATGNKNTLAVHLMAQGLYNHSTTAKEGKSDSE 333
>gi|126090909 engrailed homeobox 1 [Homo sapiens]
Length = 392
Score = 277 bits (708), Expect = 1e-74
Identities = 181/394 (45%), Positives = 203/394 (51%), Gaps = 63/394 (15%)
Query: 1 MEENDPKP--------GEAAAAVEGQRQPESSPGGGSGGGGGS-------SPGEADTGRR 45
MEE P+P G AAAA G SPG G GS SP A
Sbjct: 1 MEEQQPEPKSQRDSALGAAAAATPGGLSLSLSPGASGSSGSGSDGDSVPVSPQPAPPSPP 60
Query: 46 RALMLPAVLQAPGNHQHP---------------------HRITNFFIDNILRPEFGRRKD 84
A LP + P HP HR TNFFIDNILRP+FG +K+
Sbjct: 61 AAPCLPPLAHHPHLPPHPPPPPPQHLAAPAHQPQPAAQLHRTTNFFIDNILRPDFGCKKE 120
Query: 85 AGTCCAGAGGGRGGGAGGEGGASGAEGGGGAGGSEQLLGSGSREP-RQNPPCAPGAGGPL 143
GGAGG GG + G A G + + G+R P + CAP A
Sbjct: 121 QPPPQLLVAAAARGGAGG-GGRVERDRGQTAAGRDPVHPLGTRAPGAASLLCAPDANCG- 178
Query: 144 PAAGSDSPGDGEGGSKT------------------------LSLHGGAKKGGDPGGPLDG 179
P GS G G SK S GG GG G P
Sbjct: 179 PPDGSQPAAAGAGASKAGNPAAAAAAAAAAVAAAAAAAAAKPSDTGGGGSGGGAGSPGAQ 238
Query: 180 SLKARGLGGGDLSVSSDSDSSQAGANLGAQPMLWPAWVYCTRYSDRPSSGPRSRKPKKKN 239
K G + + ++ QP++WPAWVYCTRYSDRPSSGPR+RK KKK
Sbjct: 239 GTKYPEHGNPAILLMGSANGGPVVKTDSQQPLVWPAWVYCTRYSDRPSSGPRTRKLKKKK 298
Query: 240 PNKEDKRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKI 299
KEDKRPRTAFTAEQLQRLKAEFQ NRY+TEQRRQ+LAQELSLNESQIKIWFQNKRAKI
Sbjct: 299 NEKEDKRPRTAFTAEQLQRLKAEFQANRYITEQRRQTLAQELSLNESQIKIWFQNKRAKI 358
Query: 300 KKATGNKNTLAVHLMAQGLYNHSTTAKEGKSDSE 333
KKATG KN LA+HLMAQGLYNHSTT + K +SE
Sbjct: 359 KKATGIKNGLALHLMAQGLYNHSTTTVQDKDESE 392
>gi|89257348 homeo box HB9 [Homo sapiens]
Length = 401
Score = 90.9 bits (224), Expect = 1e-18
Identities = 85/305 (27%), Positives = 116/305 (38%), Gaps = 65/305 (21%)
Query: 68 NFFIDNILRPEFGRRKDAG-------TCCAGAGGGRGGGAGGEGGASGAEGGGGAGGSEQ 120
NF ID +L + R A T A A G GGG GG GGASG G + S +
Sbjct: 6 NFRIDALLAVDPPRAASAQSAPLALVTSLAAAASGTGGGGGG-GGASGGTSGSCSPASSE 64
Query: 121 LLGSGSREPRQNPPCAPGAGGP----LPAAGSDSPGDGEGGSKTLSLHGGAKKGGDPGGP 176
+ + R P P LP G G G GG T HGG PG
Sbjct: 65 PPAAPADRLRAESPSPPRLLAAHCALLPKPGFLGAGGGGGG--TGGGHGGPHHHAHPGAA 122
Query: 177 LDGSLKARGLGGGDLSVSSDSDSSQAGANLGAQPMLW--PAWVYCTRYSDRPSSG----- 229
+ A G L++ +Q GA L AQ L+ P + Y + +G
Sbjct: 123 AAAAAAAAAAAAGGLALGLHPGGAQGGAGLPAQAALYGHPVYGYSAAAAAAALAGQHPAL 182
Query: 230 --------------------------------------------PRSRKPKKKNPNKEDK 245
P + N + +
Sbjct: 183 SYSYPQVQGAHPAHPADPIKLGAGTFQLDQWLRASTAGMILPKMPDFNSQAQSNLLGKCR 242
Query: 246 RPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKIKKATGN 305
RPRTAFT++QL L+ +F+ N+YL+ +R +A L L E+Q+KIWFQN+R K K++
Sbjct: 243 RPRTAFTSQQLLELEHQFKLNKYLSRPKRFEVATSLMLTETQVKIWFQNRRMKWKRSKKA 302
Query: 306 KNTLA 310
K A
Sbjct: 303 KEQAA 307
>gi|24497517 homeobox A5 [Homo sapiens]
Length = 270
Score = 87.8 bits (216), Expect = 1e-17
Identities = 78/225 (34%), Positives = 99/225 (44%), Gaps = 32/225 (14%)
Query: 94 GGRGGGAGGEGGASGAEGGGGAGGSEQL------LGSGSREPRQNPPCAPGAG---GPLP 144
G G G G + G G G G E+ + EPR + P PLP
Sbjct: 43 GRYGYGYNGMDLSVGRSGSGHFGSGERARSYAASASAAPAEPRYSQPATSTHSPQPDPLP 102
Query: 145 -AAGSDSPGDGE--GGSKTLSLHGGAKKGGDPGGPLDGSLKARGLGGG---DLSVSSDSD 198
+A + SPG GG +LS GA D G S + G G D SS+
Sbjct: 103 CSAVAPSPGSDSHHGGKNSLSNSSGAS--ADAGSTHISSREGVGTASGAEEDAPASSEQA 160
Query: 199 SSQAGANLG--AQPMLWPAWVYCTRYSDRPSSGPRSRKPKKKNPNKEDKRPRTAFTAEQL 256
S+Q+ + AQP ++P W+ S GP E KR RTA+T Q
Sbjct: 161 SAQSEPSPAPPAQPQIYP-WMRKLHISHDNIGGP------------EGKRARTAYTRYQT 207
Query: 257 QRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKIKK 301
L+ EF NRYLT +RR +A L L+E QIKIWFQN+R K KK
Sbjct: 208 LELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 252
>gi|239742243 PREDICTED: HPX-153 homeobox [Homo sapiens]
Length = 411
Score = 86.7 bits (213), Expect = 3e-17
Identities = 77/246 (31%), Positives = 99/246 (40%), Gaps = 30/246 (12%)
Query: 78 EFGRRKDAGTCCAGAGGGRGGGAG-----GEGGASGAEG-GGGAGGSEQLLGSGSREPRQ 131
E RR AG GA G AG GE + G G GG SG P
Sbjct: 97 ELERRALAGAGGVGAAGAEPPNAGDPFKAGEAETNDTNGYSSGGGGHSPSADSGDEVPDD 156
Query: 132 NPPCAPGAGGPLPAAGSDSPGDGEGG--SKTLSLHGGAKKGGDPGGPLDGSLKARGLGGG 189
A A G++ G GG ++ G A+ PG +D +A G
Sbjct: 157 EDDDEDEAPETEAARGAEEARGGGGGLGARGSGCQGAAETDASPGATVD---EAAAPGPR 213
Query: 190 DLSVSSDSDSSQAGANLGAQPMLWPAWVYCTRYSDRPSSGPRSRKPKKKNPNKEDK---- 245
+ S + A A GA P + KPK+K + K
Sbjct: 214 ENSPVAQGPPGGAAAPGGA--------------GTTPQGTATAAKPKRKRTGSDSKSGKP 259
Query: 246 -RPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKIKKATG 304
R RTAFT EQL L+ +F+ RYL+ R +LA LSL E+Q+KIWFQN+R K KK
Sbjct: 260 RRARTAFTYEQLVALENKFKATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNP 319
Query: 305 NKNTLA 310
+T A
Sbjct: 320 GADTSA 325
Score = 37.0 bits (84), Expect = 0.025
Identities = 46/171 (26%), Positives = 59/171 (34%), Gaps = 31/171 (18%)
Query: 6 PKPGEAAAAVEGQRQPESSPGGGSGGGGGSSPGEADTGRRRALMLPAVLQAPGNHQHPHR 65
P G+ A E + + G S GGGG SP AD+G + P +
Sbjct: 117 PNAGDPFKAGEAET---NDTNGYSSGGGGHSP-SADSGD----------EVPDDEDD--- 159
Query: 66 ITNFFIDNILRPEFGRRKDAGTCCAGAGGGRGGGAGGEGGASGAEGGGGAGGSEQLLGSG 125
D PE + A G GGG G G GA+ + GA E +
Sbjct: 160 ------DEDEAPETEAARGAEE-ARGGGGGLGARGSGCQGAAETDASPGATVDE----AA 208
Query: 126 SREPRQNPPCAPGAGGPLPA---AGSDSPGDGEGGSKTLSLHGGAKKGGDP 173
+ PR+N P A G G A AG+ G G K G P
Sbjct: 209 APGPRENSPVAQGPPGGAAAPGGAGTTPQGTATAAKPKRKRTGSDSKSGKP 259
>gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens]
Length = 814
Score = 86.3 bits (212), Expect = 4e-17
Identities = 77/246 (31%), Positives = 99/246 (40%), Gaps = 30/246 (12%)
Query: 78 EFGRRKDAGTCCAGAGGGRGGGAG-----GEGGASGAEG-GGGAGGSEQLLGSGSREPRQ 131
E RR AG GA G AG GE + G G GG SG P
Sbjct: 500 ELERRALAGAGGVGAAGAEPPNAGDPFKAGEAETNDTNGYSSGGGGHSPSADSGDEVPDD 559
Query: 132 NPPCAPGAGGPLPAAGSDSPGDGEGG--SKTLSLHGGAKKGGDPGGPLDGSLKARGLGGG 189
A A G++ G GG ++ G A+ PG +D +A G
Sbjct: 560 EDDDEDEAPETEAARGAEEARGGGGGLGARGSGCQGAAETDASPGATVD---EAAAPGPR 616
Query: 190 DLSVSSDSDSSQAGANLGAQPMLWPAWVYCTRYSDRPSSGPRSRKPKKKNPNKEDK---- 245
+ S + A A GA P + KPK+K + K
Sbjct: 617 ENSPVAPGPPGGAAAPGGA--------------GTTPQGTATAAKPKRKRTGSDSKSGKP 662
Query: 246 -RPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKIKKATG 304
R RTAFT EQL L+ +F+ RYL+ R +LA LSL E+Q+KIWFQN+R K KK
Sbjct: 663 RRARTAFTYEQLVALENKFKATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNP 722
Query: 305 NKNTLA 310
+T A
Sbjct: 723 GADTSA 728
Score = 40.0 bits (92), Expect = 0.003
Identities = 47/171 (27%), Positives = 60/171 (35%), Gaps = 31/171 (18%)
Query: 6 PKPGEAAAAVEGQRQPESSPGGGSGGGGGSSPGEADTGRRRALMLPAVLQAPGNHQHPHR 65
P G+ A E + + G S GGGG SP AD+G + P +
Sbjct: 520 PNAGDPFKAGEAET---NDTNGYSSGGGGHSP-SADSGD----------EVPDDEDD--- 562
Query: 66 ITNFFIDNILRPEFGRRKDAGTCCAGAGGGRGGGAGGEGGASGAEGGGGAGGSEQLLGSG 125
D PE + A G GGG G G GA+ + GA E +
Sbjct: 563 ------DEDEAPETEAARGAEE-ARGGGGGLGARGSGCQGAAETDASPGATVDE----AA 611
Query: 126 SREPRQNPPCAPGAGGPLPA---AGSDSPGDGEGGSKTLSLHGGAKKGGDP 173
+ PR+N P APG G A AG+ G G K G P
Sbjct: 612 APGPRENSPVAPGPPGGAAAPGGAGTTPQGTATAAKPKRKRTGSDSKSGKP 662
>gi|23397672 homeobox D4 [Homo sapiens]
Length = 255
Score = 84.7 bits (208), Expect = 1e-16
Identities = 74/216 (34%), Positives = 89/216 (41%), Gaps = 31/216 (14%)
Query: 101 GGEGGASGAE--GGGGAGGSEQLLGSGSREPRQNPP---CAPGAGGPLPAAGSDSPGDGE 155
GG G GA+ GGG G Q G R P PG G LPA G G
Sbjct: 26 GGYLGEQGADYYGGGAQGADFQPPGLYPRPDFGEQPFGGSGPGPGSALPARGHGQEPGGP 85
Query: 156 GGSKTLSLHGGAKKGGDPGGPLDGSLKARGLGGGDLSVSSDSDSSQAGANLGAQPMLWPA 215
GG P PL G AR SD +G L +++P
Sbjct: 86 GGHYAAPGEPCPAPPAPPPAPLPG---ARAYS------QSDPKQPPSGTALKQPAVVYP- 135
Query: 216 WVYCTRYSDRPSSGPRSRKPKKKNPNK---EDKRPRTAFTAEQLQRLKAEFQTNRYLTEQ 272
W+ + NPN E KR RTA+T +Q+ L+ EF NRYLT +
Sbjct: 136 WM-------------KKVHVNSVNPNYTGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRR 182
Query: 273 RRQSLAQELSLNESQIKIWFQNKRAKIKKATGNKNT 308
RR +A L L+E QIKIWFQN+R K KK NT
Sbjct: 183 RRIEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNT 218
Score = 31.6 bits (70), Expect = 1.0
Identities = 27/78 (34%), Positives = 31/78 (39%), Gaps = 14/78 (17%)
Query: 76 RPEFGRRKDAGTCCAGAGGGRGGGAGGEGGASGAEGGGGAGGSEQLLGSGSREPRQNPPC 135
RP+FG + G+ G G G A G G G GG A E P PP
Sbjct: 54 RPDFGEQPFGGS---GPGPGSALPARGHGQEPGGPGGHYAAPGE---------PCPAPPA 101
Query: 136 APGAGGPLPAAGSDSPGD 153
P A PLP A + S D
Sbjct: 102 PPPA--PLPGARAYSQSD 117
>gi|5031757 T-cell leukemia homeobox 1 [Homo sapiens]
Length = 330
Score = 84.7 bits (208), Expect = 1e-16
Identities = 73/219 (33%), Positives = 102/219 (46%), Gaps = 25/219 (11%)
Query: 91 GAGGGRGGGAGGEGGASGAEGGGGAGGSEQLLGSGSREPRQNPPCAPGAGGPLPAAGSDS 150
GAGG G GG GG G GGGGA L GS + AGGP P G
Sbjct: 67 GAGGAGAYGTGGPGGPGGPAGGGGACSMGPLTGSYNVNMAL-------AGGPGPGGG--- 116
Query: 151 PGDGEGGSKTLSLHGGAKKGGDPGGPLDGSLK-ARGLGGGDLSVSSDSDSSQAGANLGAQ 209
G GG+ LS G + PL G++ + L G +V S + G N
Sbjct: 117 -GGSSGGAGALSAAGVIRVPAHR--PLAGAVAHPQPLATGLPTVPSVP--AMPGVN-NLT 170
Query: 210 PMLWPAWVYCTRYS-DRPSSGP-RSRKPKKKNPNKEDKRPRTAFTAEQLQRLKAEFQTNR 267
+ +P RY+ DR + P ++R P KK K+PRT+FT Q+ L+ F +
Sbjct: 171 GLTFPWMESNRRYTKDRFTGHPYQNRTPPKK------KKPRTSFTRLQICELEKRFHRQK 224
Query: 268 YLTEQRRQSLAQELSLNESQIKIWFQNKRAKIKKATGNK 306
YL R +LA+ L + ++Q+K WFQN+R K ++ T +
Sbjct: 225 YLASAERAALAKALKMTDAQVKTWFQNRRTKWRRQTAEE 263
Score = 28.9 bits (63), Expect = 6.7
Identities = 15/38 (39%), Positives = 17/38 (44%)
Query: 26 GGGSGGGGGSSPGEADTGRRRALMLPAVLQAPGNHQHP 63
G G GGGGGSS G + +PA G HP
Sbjct: 110 GPGPGGGGGSSGGAGALSAAGVIRVPAHRPLAGAVAHP 147
>gi|7110735 ventral anterior homeobox 2 [Homo sapiens]
Length = 290
Score = 82.0 bits (201), Expect = 7e-16
Identities = 61/161 (37%), Positives = 84/161 (52%), Gaps = 14/161 (8%)
Query: 152 GDG-----EGGSKTLSLHGGAKKGGDPGGPLDGSLKARGLGGGDLSVSSDSDSSQAG--- 203
GDG G ++ GG + GD G G L+A G G V+ S SS AG
Sbjct: 2 GDGGAERDRGPARRAESGGGGGRCGDRSGA--GDLRADGGGHSPTEVAGTSASSPAGSRE 59
Query: 204 --ANLGAQPMLWPAWVYCTRYSDRPSSGPRSRKPKKKNPNKE-DKRPRTAFTAEQLQRLK 260
A+ QP A +C R R + G K + + KR RT+FTAEQL RL+
Sbjct: 60 SGADSDGQPGPGEA-DHCRRILVRDAKGTIREIVLPKGLDLDRPKRTRTSFTAEQLYRLE 118
Query: 261 AEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKIKK 301
EFQ +Y+ + R LA++L+L+E+Q+K+WFQN+R K KK
Sbjct: 119 MEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKK 159
Score = 33.9 bits (76), Expect = 0.21
Identities = 23/77 (29%), Positives = 28/77 (36%), Gaps = 10/77 (12%)
Query: 80 GRRKDAGTCCAGAGGGRGGGAGGEGGASGAEGGGGAGGSEQLLGSGSREPRQNPPCAPGA 139
G +D G GG GG G GA GG ++ G+ + P A
Sbjct: 5 GAERDRGPARRAESGGGGGRCGDRSGAGDLRADGGGHSPTEVAGTSASSP---------A 55
Query: 140 GGPLPAAGSD-SPGDGE 155
G A SD PG GE
Sbjct: 56 GSRESGADSDGQPGPGE 72
>gi|94536800 empty spiracles homolog 1 [Homo sapiens]
Length = 290
Score = 77.8 bits (190), Expect = 1e-14
Identities = 69/209 (33%), Positives = 90/209 (43%), Gaps = 21/209 (10%)
Query: 103 EGGASGAEGGGGAGGSEQLLGSGSREP-RQNPPCAPGAGGPLPAAGSDSPGDGEGGSKTL 161
+GG G GGGGA GS L + S EP R P A S P G+
Sbjct: 52 DGGTGGGTGGGGA-GSHLLAAAASEEPLRPTALNYPHPSAAEAAFVSGFPAAAAAGAGR- 109
Query: 162 SLHGGAKK--GGDPGGPLDGSLKARGLGGGDLSVSSDSDSSQAGANLGAQPMLWPAWVYC 219
SL+GG + P A LG L +Q P+ + WV
Sbjct: 110 SLYGGPELVFPEAMNHPALTVHPAHQLGASPLQPPHSFFGAQ-----HRDPLHFYPWVLR 164
Query: 220 TRY-------SDRPSSGPRSRKPKKKNPNKEDKRPRTAFTAEQLQRLKAEFQTNRYLTEQ 272
R+ SD P G P + P KR RTAF+ QL RL+ F+ N Y+
Sbjct: 165 NRFFGHRFQASDVPQDGLLLHGPFARKP----KRIRTAFSPSQLLRLERAFEKNHYVVGA 220
Query: 273 RRQSLAQELSLNESQIKIWFQNKRAKIKK 301
R+ LA LSL+E+Q+K+WFQN+R K K+
Sbjct: 221 ERKQLAGSLSLSETQVKVWFQNRRTKYKR 249
>gi|19923391 homeobox D3 [Homo sapiens]
Length = 432
Score = 77.4 bits (189), Expect = 2e-14
Identities = 66/219 (30%), Positives = 93/219 (42%), Gaps = 45/219 (20%)
Query: 94 GGRGGGAGGEGGASGAEGGGGAGGSEQLLGSGSREPRQNPPCAPGAGGPLPAAGSDSPGD 153
G G+ G ++GGGG GS+ + ++P Q PP P LP + +PG
Sbjct: 83 GAELNGSCMRPGTGNSQGGGG--GSQPPGLNSEQQPPQPPPPPP----TLPPSSPTNPGG 136
Query: 154 GEGGSKTLSLHGGAKKGGDPGGPLDGSLKARGLGGGDLSVSSDSDSSQAGANLGAQPMLW 213
G K GGP ++S + A + Q ++
Sbjct: 137 GVPAKKP------------KGGP---------------------NASSSSATISKQ--IF 161
Query: 214 PAWVYCTRYSDRPSSGPRSRKPK---KKNPNKEDKRPRTAFTAEQLQRLKAEFQTNRYLT 270
P W+ +R + + + + K P KR RTA+T+ QL L+ EF NRYL
Sbjct: 162 P-WMKESRQNSKQKNSCATAGESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLC 220
Query: 271 EQRRQSLAQELSLNESQIKIWFQNKRAKIKKATGNKNTL 309
RR +A L+L E QIKIWFQN+R K KK K L
Sbjct: 221 RPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKAKGIL 259
>gi|149588930 gastrulation brain homeo box 1 [Homo sapiens]
Length = 363
Score = 76.6 bits (187), Expect = 3e-14
Identities = 99/338 (29%), Positives = 129/338 (38%), Gaps = 75/338 (22%)
Query: 18 QRQPESSPGGGSGGGGGSSPGEAD------------------TGRR-----RALMLP-AV 53
QR S GG+GGGGG PG A TG R L+LP A+
Sbjct: 2 QRAGGGSAPGGNGGGGGGGPGTAFSIDSLIGPPPPRSGHLLYTGYPMFMPYRPLVLPQAL 61
Query: 54 LQAPGNHQHPH---------RITNFFIDNILR------------PEFGRRKDAG------ 86
AP P R+TN F + + P F DA
Sbjct: 62 APAPLPAGLPPLAPLASFAGRLTNTFCAGLGQAVPSMVALTTALPSFAEPPDAFYGPQEL 121
Query: 87 TCCAGAGGGRGGGAGGEGGASGAEGGGGAGGSEQLLGSGSREPRQNPPCAPGAGGPLPAA 146
A A E G EGG A ++LL + + PP P P+
Sbjct: 122 AAAAAAAAATAARNNPEPGGRRPEGGLEA---DELLPAREKVAEPPPPPPPHFSETFPSL 178
Query: 147 GSDSPGDGEG-GSKTLSLHGGAKKGGDPGGPLDGSLKARGLGGGDLSVSSDSDSSQAG-- 203
P +G+ S L A GDP G S + GGD DSS G
Sbjct: 179 ----PAEGKVYSSDEEKLEASA---GDPAG----SEQEEEGSGGDSEDDGFLDSSAGGPG 227
Query: 204 ANLGAQPMLWPAWVYCTRYSDRPSSGPRSRKPKKKNPNKEDKRPRTAFTAEQLQRLKAEF 263
A LG +P L + ++G + P + +R RTAFT+EQL L+ EF
Sbjct: 228 ALLGPKPKLKGSLGTGAEEGAPVTAGVTA-------PGGKSRRRRTAFTSEQLLELEKEF 280
Query: 264 QTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKIKK 301
+YL+ R +A L L+E Q+KIWFQN+RAK K+
Sbjct: 281 HCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKR 318
>gi|23510368 homeobox D11 [Homo sapiens]
Length = 338
Score = 76.3 bits (186), Expect = 4e-14
Identities = 82/306 (26%), Positives = 111/306 (36%), Gaps = 66/306 (21%)
Query: 6 PKPGEAAAAVEGQRQPESSPGGGSGGGGGSSPGEADTGRRRALMLPAVLQAPGNHQHPHR 65
P G G PGGG GG GG +P A A A A
Sbjct: 74 PYRGGGGGGSAGGGSSGGGPGGGGGGAGGYAPYYAAAAAAAAAAAAAEEAA--------- 124
Query: 66 ITNFFIDNILRPEFGRRKD----AGTCCAGAGGGRGGGAGGEGGASGAEGGGGA--GGSE 119
+ L P GRR D A A G G AG A G G G +
Sbjct: 125 -----MQRELLPPAGRRPDVLFKAPEPVCAAPGPPHGPAGAASNFYSAVGRNGILPQGFD 179
Query: 120 QLLGSGSREPRQNPPCAPGAGGPLPAAGSDS----PGDGEGGSKTLSLHGGAKKGGDPGG 175
Q + P P P P P +D G G GG + A G +P G
Sbjct: 180 QFYEAAPGPPFAGPQPPPPPAPPQPEGAADKGDPRTGAGGGGGSPCTK---ATPGSEPKG 236
Query: 176 PLDGSLKARGLGGGDLSVSSDSDSSQAGANLGAQPMLWPAWVYCTRYSDRPSSGPRSRKP 235
+GS GGD + +AGA ++ SS ++
Sbjct: 237 AAEGS-------GGD----GEGPPGEAGA-------------------EKSSSAVAPQRS 266
Query: 236 KKKNPNKEDKRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNK 295
+KK R +T Q++ L+ EF N Y+ +++R L++ L+L + Q+KIWFQN+
Sbjct: 267 RKK---------RCPYTKYQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNR 317
Query: 296 RAKIKK 301
R K KK
Sbjct: 318 RMKEKK 323
>gi|162951873 ventral anterior homeobox 1 isoform a [Homo sapiens]
Length = 334
Score = 75.9 bits (185), Expect = 5e-14
Identities = 51/158 (32%), Positives = 81/158 (51%), Gaps = 8/158 (5%)
Query: 153 DGEGGSKTLSLHGGAKKGGDPGGPLDGSLKARGLGGGDLSVSSDSDSSQAGANLGAQPML 212
D E + + H +++ G L + G S +++ D +++ +N A P
Sbjct: 15 DAEAARVSKNAHKESRESKGAEGNLPAAFLKEPQGAFSASGAAE-DCNKSKSNSAADPD- 72
Query: 213 WPAWVYCTRYSDRPSSGPRSRKPKKKNPNKE-DKRPRTAFTAEQLQRLKAEFQTNRYLTE 271
YC R R + G K + + KR RT+FTAEQL RL+ EFQ +Y+
Sbjct: 73 -----YCRRILVRDAKGSIREIILPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVG 127
Query: 272 QRRQSLAQELSLNESQIKIWFQNKRAKIKKATGNKNTL 309
+ R LA++L+L+E+Q+K+WFQN+R K KK G + L
Sbjct: 128 RERTELARQLNLSETQVKVWFQNRRTKQKKDQGKDSEL 165
Score = 33.5 bits (75), Expect = 0.27
Identities = 39/145 (26%), Positives = 50/145 (34%), Gaps = 19/145 (13%)
Query: 99 GAGGEGGASGAEGGGGAGGSEQLLGSGSREPRQNPPCAPGAGGPLPAAGSDSPGDGEGGS 158
G+ G + A G G A GS + + P GA P P A +PG G G
Sbjct: 206 GSALRGPSLPALGAGAAAGSAAAAAAAA-------PGPAGAASPHPPAVGGAPGPGPAGP 258
Query: 159 KTLSLHGGAKKGGDPGGPLDGSLKARGLGGGDLSVSSDSDSSQAGANLGAQPMLWPAWVY 218
GG G G SL L G S S + + AG+ G L
Sbjct: 259 ------GGLHAGAPAAGHSLFSLPVPSLLGSVASRLSSAPLTMAGSLAGNLQEL------ 306
Query: 219 CTRYSDRPSSGPRSRKPKKKNPNKE 243
RY + P SR K+ K+
Sbjct: 307 SARYLSSSAFEPYSRTNNKEGAEKK 331
>gi|194363768 homeobox D9 [Homo sapiens]
Length = 352
Score = 75.1 bits (183), Expect = 8e-14
Identities = 69/241 (28%), Positives = 94/241 (39%), Gaps = 47/241 (19%)
Query: 91 GAGGGRGGGAGGEGGASGAEGGGGAGGSEQLLGSGSREPRQNPPCAPGAGGPLPAAGSDS 150
GAGGG GGG GG G G A G + +P AP ++ S S
Sbjct: 129 GAGGGGGGGGGGPGRGPSPGPSGPANGRHYGI-----KPETRAAPAPATAASTTSSSSTS 183
Query: 151 --------------PGDGEGG-----SKTLSLHGGAKKGGDPGGPLDGSLKARGLGGGDL 191
G G + L A GG GP G A G GG
Sbjct: 184 LSSSSKRTECSVARESQGSSGPEFSCNSFLQEKAAAATGGT--GPGAGIGAATGTGGSS- 240
Query: 192 SVSSDSDSSQAGANLGAQPMLWPAWVYCTRYSDRPSSGPRSRKPKKKNPN------KEDK 245
S+ SD G +L + ++ S P+ ++ NP + +
Sbjct: 241 EPSACSDHPIPGCSL--------------KEEEKQHSQPQQQQLDPNNPAANWIHARSTR 286
Query: 246 RPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKIKKATGN 305
+ R +T Q L+ EF N YLT RR +A+ L+L E Q+KIWFQN+R K+KK +
Sbjct: 287 KKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARILNLTERQVKIWFQNRRMKMKKMSKE 346
Query: 306 K 306
K
Sbjct: 347 K 347
>gi|118582284 msh homeobox 1 [Homo sapiens]
Length = 303
Score = 73.9 bits (180), Expect = 2e-13
Identities = 68/223 (30%), Positives = 102/223 (45%), Gaps = 26/223 (11%)
Query: 92 AGGGRGGGAGGEGGASGAEGGGGAGGSEQLLGSGSREPRQNPPCAPGAGGPLPAAGSDSP 151
A G GG G+ ++ A G E+ +P+ +P P + L A P
Sbjct: 20 AFGKPAGGGAGQAPSAAAATAAAMGADEE-----GAKPKVSPSLLPFSVEAL-MADHRKP 73
Query: 152 GDGEGG---SKTLSLHGGAKK--GGDPG--GPLDGSLKARGLG----GGDLSVSSDSDSS 200
G E S+ + GG+ + G PG G D R LG GG L + D+
Sbjct: 74 GAKESALAPSEGVQAAGGSAQPLGVPPGSLGAPDAPSSPRPLGHFSVGGLLKLPEDA--- 130
Query: 201 QAGANLGAQPMLWPAWVYCTRYSDRPSS--GPRSRKPKKKNPNKEDKRPRTAFTAEQLQR 258
A +P P W+ R+S P+ P + +K +K +++PRT FT QL
Sbjct: 131 LVKAESPEKPERTP-WMQSPRFSPPPARRLSPPACTLRK---HKTNRKPRTPFTTAQLLA 186
Query: 259 LKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKIKK 301
L+ +F+ +YL+ R + LSL E+Q+KIWFQN+RAK K+
Sbjct: 187 LERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKR 229
>gi|24497526 homeobox B1 [Homo sapiens]
Length = 301
Score = 73.6 bits (179), Expect = 2e-13
Identities = 71/224 (31%), Positives = 93/224 (41%), Gaps = 38/224 (16%)
Query: 109 AEGGGGAGGSEQLLGSGSREPRQNPPCAPGA-------GGPLPAAGSDSPG--------- 152
+EG G G S S P Q PP G G PAA S S G
Sbjct: 44 SEGRYGGGLSSPAFQQNSGYPAQQPPSTLGVPFPSSAPSGYAPAACSPSYGPSQYYPLGQ 103
Query: 153 -DGEGGSKTLSLHG----GAKKGGDPGGPLDGSLKARGLGGGDLSVSSDSDSSQAGANLG 207
+G+GG S +G G G GG G + G+ +S + A A+L
Sbjct: 104 SEGDGGYFHPSSYGAQLGGLSDGYGAGGAGPGPYPPQHPPYGNEQTAS---FAPAYADLL 160
Query: 208 AQPMLWPAWVYCTRYSDRPSSGPRSRKPKKKNPNKEDKRP----------RTAFTAEQLQ 257
++ P C + P++ K+NP K K RT FT QL
Sbjct: 161 SEDKETP----CPSEPNTPTARTFDWMKVKRNPPKTAKVSEPGLGSPSGLRTNFTTRQLT 216
Query: 258 RLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKIKK 301
L+ EF N+YL+ RR +A L LNE+Q+KIWFQN+R K KK
Sbjct: 217 ELEKEFHFNKYLSRARRVEIAATLELNETQVKIWFQNRRMKQKK 260
>gi|84105335 mesenchyme homeobox 2 [Homo sapiens]
Length = 304
Score = 73.2 bits (178), Expect = 3e-13
Identities = 50/142 (35%), Positives = 71/142 (50%), Gaps = 4/142 (2%)
Query: 172 DPGGP--LDGSLKARGLGGGDLSVSSDSDSSQAGANLGAQPMLWPAWVYCTRYSDRPSSG 229
D GGP L S L S+ + ++ A + G Q L PA R S
Sbjct: 113 DSGGPPELGSSPPVLCSNSSSLGSSTPTGAACAPGDYGRQA-LSPAEAEKRSGGKRKSDS 171
Query: 230 PRSRKPKKKNP-NKEDKRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQI 288
S++ K+ N + ++ RTAFT EQ++ L+AEF + YLT RR +A L L E Q+
Sbjct: 172 SDSQEGNYKSEVNSKPRKERTAFTKEQIRELEAEFAHHNYLTRLRRYEIAVNLDLTERQV 231
Query: 289 KIWFQNKRAKIKKATGNKNTLA 310
K+WFQN+R K K+ G + A
Sbjct: 232 KVWFQNRRMKWKRVKGGQQGAA 253
>gi|148613882 homeobox A4 [Homo sapiens]
Length = 320
Score = 73.2 bits (178), Expect = 3e-13
Identities = 89/299 (29%), Positives = 114/299 (38%), Gaps = 56/299 (18%)
Query: 22 ESSPGGGSGGGGGSSPGEADTGRRRALMLPAVLQAPGNHQHPHR------ITNFFIDNIL 75
+ S GG+ GG G PG LP LQ P Q PH +++
Sbjct: 25 QHSGSGGADGGPGGGPGYQQPPAPPTQHLP--LQQP---QLPHAGGGREPTASYYAPRTA 79
Query: 76 R----PEFGRRKDAGTC-CAGAGGGRGGGAGGEGGASGAEGGGGAGGSEQLLGSGSREPR 130
R P G A G RGG + G G + L S +P+
Sbjct: 80 REPAYPAAALYPAHGAADTAYPYGYRGGASPGRPPQPEQPPAQAKGPAHGLHASHVLQPQ 139
Query: 131 QNPPCAPGAGGPLPAAGSDSPGDGEGGSKTLSLHGGAKKGGDPGGPLDGSLKARGLGGGD 190
PP P A P +P E T PG P GS A L
Sbjct: 140 LPPPLQPRAVPPA------APRRCEAAPAT------------PGVPAGGSAPACPL---- 177
Query: 191 LSVSSDSDSSQAGANLGAQPMLWPAWVYCTRYSD-RPSSGPRSRKPKKKNPNKEDKRPRT 249
+D S G G +P+++P W+ S PS E KR RT
Sbjct: 178 ----LLADKSPLGLK-GKEPVVYP-WMKKIHVSAVNPSYN-----------GGEPKRSRT 220
Query: 250 AFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKIKKATGNKNT 308
A+T +Q+ L+ EF NRYLT +RR +A L L+E Q+KIWFQN+R K KK NT
Sbjct: 221 AYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQVKIWFQNRRMKWKKDHKLPNT 279
>gi|4503615 even-skipped homeobox 1 [Homo sapiens]
Length = 407
Score = 72.8 bits (177), Expect = 4e-13
Identities = 60/201 (29%), Positives = 87/201 (43%), Gaps = 18/201 (8%)
Query: 119 EQLLGSGSREPRQNPPCAP--GAGGPLPAAGSDSPGDGEGGSKTLSLHGGAKKGGDPGGP 176
E+++ G PR PP G GGP G G + G A G P P
Sbjct: 40 EKMVPRGCLSPRAVPPATRERGGGGPEEEPVDGLAGSAAGPGAEPQVAGAAMLGPGPPAP 99
Query: 177 LDGSLKARGLGGG---------DLSVSSDSDSSQAGANL------GAQPMLW-PAWVYCT 220
SL +G ++ VS D + A G++ ++ P T
Sbjct: 100 SVDSLSGQGQPSSSDTESDFYEEIEVSCTPDCATGNAEYQHSKGSGSEALVGSPNGGSET 159
Query: 221 RYSDRPSSGPRSRKPKKKNPNKEDKRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQE 280
S+ S G S+ + + + +R RTAFT EQ+ RL+ EF Y++ RR LA
Sbjct: 160 PKSNGGSGGGGSQGTLACSASDQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAA 219
Query: 281 LSLNESQIKIWFQNKRAKIKK 301
L+L E+ IK+WFQN+R K K+
Sbjct: 220 LNLPETTIKVWFQNRRMKDKR 240
>gi|182765442 homeobox A10 isoform a [Homo sapiens]
Length = 410
Score = 72.4 bits (176), Expect = 5e-13
Identities = 89/333 (26%), Positives = 115/333 (34%), Gaps = 73/333 (21%)
Query: 17 GQRQPESSPGGGSGGGGGSSPGEADTGR----------RRALMLPAVLQAPGNHQHP--- 63
G+R +SPG G GGGGG PG G R M P P Q P
Sbjct: 86 GKRNEAASPGSG-GGGGGLGPGAHGYGPSPIDLWLDAPRSCRMEPPDGPPPPPQQQPPPP 144
Query: 64 --------HRITNFFIDNILRPEFGRRKDAGTCCA-------------------GAGGGR 96
+ F NI D+ C G G
Sbjct: 145 PQPPQPAPQATSCSFAQNIKEESSYCLYDSADKCPKVSATAAELAPFPRGPPPDGCALGT 204
Query: 97 GGGAGGEG------GASGAEGGGGAGGSEQLLGSGSREPRQNPPCAPGAGGPLPAAGSDS 150
G G A+G G GG Q LG+G P PG G LP A +
Sbjct: 205 SSGVPVPGYFRLSQAYGTAKGYGSGGGGAQQLGAGPF-----PAQPPGRGFDLPPALASG 259
Query: 151 PGDGEGGSKTLSLHGGAKKGGDPGGPLDGSLKARGLGGGDLSVSSDSDSSQAGANLGAQP 210
D + L P P A G GGG +A A+ A
Sbjct: 260 SADAARKERALD---------SPPPPT----LACGSGGGS------QGDEEAHASSSAAE 300
Query: 211 MLWPAWVYCTRYSDRPSSGPRSRKPKKKN--PNKEDKRPRTAFTAEQLQRLKAEFQTNRY 268
L PA ++ S S S+ N K ++ R +T Q L+ EF N Y
Sbjct: 301 ELSPAPSESSKASPEKDSLGNSKGENAANWLTAKSGRKKRCPYTKHQTLELEKEFLFNMY 360
Query: 269 LTEQRRQSLAQELSLNESQIKIWFQNKRAKIKK 301
LT +RR +++ + L + Q+KIWFQN+R K+KK
Sbjct: 361 LTRERRLEISRSVHLTDRQVKIWFQNRRMKLKK 393
Score = 35.8 bits (81), Expect = 0.055
Identities = 30/87 (34%), Positives = 33/87 (37%), Gaps = 17/87 (19%)
Query: 95 GRGGGAGGEGGASGAEGGGGAGGSEQLLGSGSREPRQNPPCAPGAGGPLPAAG-----SD 149
GRG GG GGA GGG GG G P + P + G P G +
Sbjct: 38 GRGEAGGGGGGA-----GGGGGGGYYAHGGVYLPPAADLPYGLQSCGLFPTLGGKRNEAA 92
Query: 150 SPGDGEGGSKTLSLHGGAKKGGDPGGP 176
SPG G GG GG G GP
Sbjct: 93 SPGSGGGG-------GGLGPGAHGYGP 112
Score = 33.5 bits (75), Expect = 0.27
Identities = 29/89 (32%), Positives = 38/89 (42%), Gaps = 9/89 (10%)
Query: 68 NFFIDNILRPEFGRRKDAGTCCAGAGGGRGGGAGGEGG-----ASGAEGGGGAGGSEQLL 122
+F +D+++ R +AG GAGGG GGG GG A+ G + G L
Sbjct: 28 SFLVDSLIS---SGRGEAGGGGGGAGGGGGGGYYAHGGVYLPPAADLPYGLQSCGLFPTL 84
Query: 123 GSGSREPRQNPPCAPGAGGPLPAAGSDSP 151
G G R +P G GG P A P
Sbjct: 85 G-GKRNEAASPGSGGGGGGLGPGAHGYGP 112
Score = 32.3 bits (72), Expect = 0.61
Identities = 25/68 (36%), Positives = 26/68 (38%), Gaps = 9/68 (13%)
Query: 92 AGGGRGGGAGGEGGASGAEGGGGAGGSEQLLGSGSREPRQNPPCA--PGAGGPLPAAGSD 149
AGGG GG GG GG A GG L + P C P GG A S
Sbjct: 42 AGGGGGGAGGGGGGGYYAHGG-------VYLPPAADLPYGLQSCGLFPTLGGKRNEAASP 94
Query: 150 SPGDGEGG 157
G G GG
Sbjct: 95 GSGGGGGG 102
>gi|20143960 distal-less homeobox 4 isoform b [Homo sapiens]
Length = 168
Score = 72.4 bits (176), Expect = 5e-13
Identities = 34/83 (40%), Positives = 51/83 (61%)
Query: 219 CTRYSDRPSSGPRSRKPKKKNPNKEDKRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLA 278
C S++P P + + + P K+ ++PRT +++ QLQ L FQ +YL R LA
Sbjct: 20 CPPDSEKPRLSPEPSERRPQAPAKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLA 79
Query: 279 QELSLNESQIKIWFQNKRAKIKK 301
+L L ++Q+KIWFQNKR+K KK
Sbjct: 80 AQLGLTQTQVKIWFQNKRSKYKK 102
>gi|24497538 homeobox C4 [Homo sapiens]
Length = 264
Score = 71.6 bits (174), Expect = 9e-13
Identities = 39/73 (53%), Positives = 47/73 (64%), Gaps = 3/73 (4%)
Query: 239 NPNK---EDKRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNK 295
NPN E KR RTA+T +Q+ L+ EF NRYLT +RR +A L L+E QIKIWFQN+
Sbjct: 148 NPNYNGGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNR 207
Query: 296 RAKIKKATGNKNT 308
R K KK NT
Sbjct: 208 RMKWKKDHRLPNT 220
>gi|24497540 homeobox C4 [Homo sapiens]
Length = 264
Score = 71.6 bits (174), Expect = 9e-13
Identities = 39/73 (53%), Positives = 47/73 (64%), Gaps = 3/73 (4%)
Query: 239 NPNK---EDKRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNK 295
NPN E KR RTA+T +Q+ L+ EF NRYLT +RR +A L L+E QIKIWFQN+
Sbjct: 148 NPNYNGGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNR 207
Query: 296 RAKIKKATGNKNT 308
R K KK NT
Sbjct: 208 RMKWKKDHRLPNT 220
>gi|239748344 PREDICTED: NK1 homeobox 1 [Homo sapiens]
Length = 653
Score = 71.6 bits (174), Expect = 9e-13
Identities = 40/90 (44%), Positives = 52/90 (57%), Gaps = 5/90 (5%)
Query: 226 PSSGPRSRKPKKKNPNKEDK-----RPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQE 280
P + KPK+K + K R RTAFT EQL L+ +F+ RYL+ R +LA
Sbjct: 74 PQGTATAAKPKRKRTGSDSKSGKPRRARTAFTYEQLVALENKFKATRYLSVCERLNLALS 133
Query: 281 LSLNESQIKIWFQNKRAKIKKATGNKNTLA 310
LSL E+Q+KIWFQN+R K KK +T A
Sbjct: 134 LSLTETQVKIWFQNRRTKWKKQNPGADTSA 163
>gi|13273315 homeobox B4 [Homo sapiens]
Length = 251
Score = 71.6 bits (174), Expect = 9e-13
Identities = 39/73 (53%), Positives = 47/73 (64%), Gaps = 3/73 (4%)
Query: 239 NPNK---EDKRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNK 295
NPN E KR RTA+T +Q+ L+ EF NRYLT +RR +A L L+E QIKIWFQN+
Sbjct: 154 NPNYAGGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRVEIAHALCLSERQIKIWFQNR 213
Query: 296 RAKIKKATGNKNT 308
R K KK NT
Sbjct: 214 RMKWKKDHKLPNT 226
>gi|20143962 distal-less homeobox 4 isoform a [Homo sapiens]
Length = 240
Score = 71.2 bits (173), Expect = 1e-12
Identities = 33/79 (41%), Positives = 50/79 (63%)
Query: 223 SDRPSSGPRSRKPKKKNPNKEDKRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELS 282
S++P P + + + P K+ ++PRT +++ QLQ L FQ +YL R LA +L
Sbjct: 96 SEKPRLSPEPSERRPQAPAKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLG 155
Query: 283 LNESQIKIWFQNKRAKIKK 301
L ++Q+KIWFQNKR+K KK
Sbjct: 156 LTQTQVKIWFQNKRSKYKK 174
>gi|226437602 NK1 homeobox 2 [Homo sapiens]
Length = 310
Score = 70.9 bits (172), Expect = 2e-12
Identities = 62/185 (33%), Positives = 85/185 (45%), Gaps = 30/185 (16%)
Query: 124 SGSREPRQNPPCAPGAGGPLPAAGSDSPGDGEGGSKTLSLHGGAKKGGDPGGPLDGSLKA 183
+ SR+P + AG P AG SP +G + + DP P A
Sbjct: 59 ASSRDPVRQLETPDAAG---PGAGQASPLEGSEAEEE-------EDAEDPRRPRLRERAA 108
Query: 184 RGLGGGDLSVSSDSDSSQAGANLGAQPMLWPAWVYCTRYSD----RPSSGPRSRKPKKKN 239
R L G + S + AGA +P C P P S +P+++
Sbjct: 109 RLLPG-----LARSPDAPAGALASGEP--------CEDGGGGPVRSPPGSPGSPRPRRRR 155
Query: 240 --PN-KEDKRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKR 296
PN + +R RTAFT EQL L+ +F+ RYL+ R +LA LSL E+Q+KIWFQN+R
Sbjct: 156 LEPNCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRR 215
Query: 297 AKIKK 301
K KK
Sbjct: 216 TKWKK 220
Score = 35.4 bits (80), Expect = 0.072
Identities = 23/66 (34%), Positives = 31/66 (46%), Gaps = 7/66 (10%)
Query: 93 GGGRGGGAGGEGGASGAEGGGGAGGSEQLLGSGSREPRQNPPCA-------PGAGGPLPA 145
G + GG + GA+G GGGG+GGS G+G+ + P + A PL A
Sbjct: 227 GAAQVGGGAPQPGAAGGGGGGGSGGSPGPPGTGALHFQTFPSYSAANVLFPSAASFPLTA 286
Query: 146 AGSDSP 151
A SP
Sbjct: 287 AAPGSP 292
Score = 35.0 bits (79), Expect = 0.093
Identities = 18/37 (48%), Positives = 20/37 (54%), Gaps = 1/37 (2%)
Query: 8 PGEAAAAVEGQRQPE-SSPGGGSGGGGGSSPGEADTG 43
PG AA G P+ + GGG GGG G SPG TG
Sbjct: 223 PGADGAAQVGGGAPQPGAAGGGGGGGSGGSPGPPGTG 259
Score = 28.5 bits (62), Expect = 8.7
Identities = 18/46 (39%), Positives = 20/46 (43%), Gaps = 8/46 (17%)
Query: 137 PGAGGPLPAAG-SDSPGDGEGGSKTLSLHGGAKKGGDPGGPLDGSL 181
PGA G G + PG GG GG GG PG P G+L
Sbjct: 223 PGADGAAQVGGGAPQPGAAGGG-------GGGGSGGSPGPPGTGAL 261
>gi|91208415 mesenchyme homeobox 1 isoform 3 [Homo sapiens]
Length = 139
Score = 70.9 bits (172), Expect = 2e-12
Identities = 36/85 (42%), Positives = 53/85 (62%), Gaps = 10/85 (11%)
Query: 232 SRKPKKKNPNKEDK----------RPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQEL 281
SR+ K+ + N+E++ + RTAFT EQL+ L+AEF + YLT RR +A L
Sbjct: 34 SRRRKESSDNQENRGKPEGSSKARKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNL 93
Query: 282 SLNESQIKIWFQNKRAKIKKATGNK 306
L+E Q+K+WFQN+R K K+ G +
Sbjct: 94 DLSERQVKVWFQNRRMKWKRVKGGQ 118
>gi|4758710 mesenchyme homeobox 1 isoform 1 [Homo sapiens]
Length = 254
Score = 70.9 bits (172), Expect = 2e-12
Identities = 36/85 (42%), Positives = 53/85 (62%), Gaps = 10/85 (11%)
Query: 232 SRKPKKKNPNKEDK----------RPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQEL 281
SR+ K+ + N+E++ + RTAFT EQL+ L+AEF + YLT RR +A L
Sbjct: 149 SRRRKESSDNQENRGKPEGSSKARKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNL 208
Query: 282 SLNESQIKIWFQNKRAKIKKATGNK 306
L+E Q+K+WFQN+R K K+ G +
Sbjct: 209 DLSERQVKVWFQNRRMKWKRVKGGQ 233
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.131 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,294,761
Number of Sequences: 37866
Number of extensions: 1173420
Number of successful extensions: 30901
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 892
Number of HSP's successfully gapped in prelim test: 748
Number of HSP's that attempted gapping in prelim test: 9083
Number of HSP's gapped (non-prelim): 10886
length of query: 333
length of database: 18,247,518
effective HSP length: 103
effective length of query: 230
effective length of database: 14,347,320
effective search space: 3299883600
effective search space used: 3299883600
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.