BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|7706712 sirtuin 7 [Homo sapiens] (400 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|7706712 sirtuin 7 [Homo sapiens] 808 0.0 gi|7706710 sirtuin 6 [Homo sapiens] 177 2e-44 gi|6912662 sirtuin 4 [Homo sapiens] 86 5e-17 gi|6912660 sirtuin 3 isoform a [Homo sapiens] 66 5e-11 gi|13775600 sirtuin 2 isoform 1 [Homo sapiens] 62 9e-10 gi|13775602 sirtuin 2 isoform 2 [Homo sapiens] 62 9e-10 gi|63054862 sirtuin 3 isoform b [Homo sapiens] 62 1e-09 gi|6912664 sirtuin 5 isoform 1 [Homo sapiens] 57 2e-08 gi|13787215 sirtuin 5 isoform 2 [Homo sapiens] 55 1e-07 gi|7657575 sirtuin 1 isoform a [Homo sapiens] 46 7e-05 gi|239756174 PREDICTED: hypothetical protein [Homo sapiens] 40 0.003 gi|239750672 PREDICTED: hypothetical protein [Homo sapiens] 40 0.003 gi|239744982 PREDICTED: hypothetical protein [Homo sapiens] 40 0.003 gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 39 0.008 gi|148806928 hypothetical protein LOC57482 [Homo sapiens] 39 0.008 gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 39 0.011 gi|4505101 microtubule-associated protein 7 [Homo sapiens] 38 0.014 gi|148746195 trichohyalin [Homo sapiens] 38 0.019 gi|62244004 modulator of estrogen induced transcription isoform ... 37 0.024 gi|63176611 modulator of estrogen induced transcription isoform ... 37 0.024 gi|102467235 inner centromere protein antigens 135/155kDa isofor... 37 0.024 gi|102467242 inner centromere protein antigens 135/155kDa isofor... 37 0.024 gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 37 0.032 gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 37 0.041 gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 37 0.041 gi|111955162 5-azacytidine induced 1 isoform b [Homo sapiens] 37 0.041 gi|111955084 5-azacytidine induced 1 isoform a [Homo sapiens] 37 0.041 gi|191252814 RIMS binding protein 3B [Homo sapiens] 36 0.054 gi|191252806 RIMS binding protein 3C [Homo sapiens] 36 0.054 gi|153792195 DKFZP434H0735 protein [Homo sapiens] 36 0.054 >gi|7706712 sirtuin 7 [Homo sapiens] Length = 400 Score = 808 bits (2086), Expect = 0.0 Identities = 400/400 (100%), Positives = 400/400 (100%) Query: 1 MAAGGLSRSERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTE 60 MAAGGLSRSERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTE Sbjct: 1 MAAGGLSRSERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTE 60 Query: 61 LQGRSRRREGLKRRQEEVCDDPEELRGKVRELASAVRNAKYLVVYTGAGISTAASIPDYR 120 LQGRSRRREGLKRRQEEVCDDPEELRGKVRELASAVRNAKYLVVYTGAGISTAASIPDYR Sbjct: 61 LQGRSRRREGLKRRQEEVCDDPEELRGKVRELASAVRNAKYLVVYTGAGISTAASIPDYR 120 Query: 121 GPNGVWTLLQKGRSVSAADLSEAEPTLTHMSITRLHEQKLVQHVVSQNCDGLHLRSGLPR 180 GPNGVWTLLQKGRSVSAADLSEAEPTLTHMSITRLHEQKLVQHVVSQNCDGLHLRSGLPR Sbjct: 121 GPNGVWTLLQKGRSVSAADLSEAEPTLTHMSITRLHEQKLVQHVVSQNCDGLHLRSGLPR 180 Query: 181 TAISELHGNMYIEVCTSCVPNREYVRVFDVTERTALHRHQTGRTCHKCGTQLRDTIVHFG 240 TAISELHGNMYIEVCTSCVPNREYVRVFDVTERTALHRHQTGRTCHKCGTQLRDTIVHFG Sbjct: 181 TAISELHGNMYIEVCTSCVPNREYVRVFDVTERTALHRHQTGRTCHKCGTQLRDTIVHFG 240 Query: 241 ERGTLGQPLNWEAATEAASRADTILCLGSSLKVLKKYPRLWCMTKPPSRRPKLYIVNLQW 300 ERGTLGQPLNWEAATEAASRADTILCLGSSLKVLKKYPRLWCMTKPPSRRPKLYIVNLQW Sbjct: 241 ERGTLGQPLNWEAATEAASRADTILCLGSSLKVLKKYPRLWCMTKPPSRRPKLYIVNLQW 300 Query: 301 TPKDDWAALKLHGKCDDVMRLLMAELGLEIPAYSRWQDPIFSLATPLRAGEEGSHSRKSL 360 TPKDDWAALKLHGKCDDVMRLLMAELGLEIPAYSRWQDPIFSLATPLRAGEEGSHSRKSL Sbjct: 301 TPKDDWAALKLHGKCDDVMRLLMAELGLEIPAYSRWQDPIFSLATPLRAGEEGSHSRKSL 360 Query: 361 CRSREEAPPGDRGAPLSSAPILGGWFGRGCTKRTKRKKVT 400 CRSREEAPPGDRGAPLSSAPILGGWFGRGCTKRTKRKKVT Sbjct: 361 CRSREEAPPGDRGAPLSSAPILGGWFGRGCTKRTKRKKVT 400 >gi|7706710 sirtuin 6 [Homo sapiens] Length = 355 Score = 177 bits (448), Expect = 2e-44 Identities = 120/281 (42%), Positives = 156/281 (55%), Gaps = 41/281 (14%) Query: 77 EVCDDPEELRGKVRELASAVRNAKYLVVYTGAGISTAASIPDYRGPNGVWTLLQKGRSVS 136 E+ D PEEL KV ELA V + +V +TGAGISTA+ IPD+RGP+GVWT+ ++G + Sbjct: 22 EIFDPPEELERKVWELARLVWQSSSVVFHTGAGISTASGIPDFRGPHGVWTMEERGLAPK 81 Query: 137 AADLSE-AEPTLTHMSITRLHEQKLVQHVVSQNCDGLHLRSGLPRTAISELHGNMYIEVC 195 E A PT THM++ +L L++ +VSQN DGLH+RSG PR ++ELHGNM++E C Sbjct: 82 FDTTFESARPTQTHMALVQLERVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEEC 141 Query: 196 TSCVPNREYVRVFDVTERTALHRHQTGRTC--------HKCGTQLRDTIVHFGERGTLGQ 247 C +YVR D T + TGR C C +LRDTI Sbjct: 142 AKC--KTQYVR--DTVVGT-MGLKATGRLCTVAKARGLRACRGELRDTI----------- 185 Query: 248 PLNWE---------AATEAASRADTILCLGSSLKVLKKYPRLWCMTKPPSRRPKLYIVNL 298 L+WE A EA+ AD + LG+SL++ + L TK R +L IVNL Sbjct: 186 -LDWEDSLPDRDLALADEASRNADLSITLGTSLQI-RPSGNLPLATK--RRGGRLVIVNL 241 Query: 299 QWTPKDDWAALKLHGKCDDVMRLLMAELGLEIPAYSRWQDP 339 Q T D A L++HG D+VM LM LGLEIPA W P Sbjct: 242 QPTKHDRHADLRIHGYVDEVMTRLMEHLGLEIPA---WDGP 279 >gi|6912662 sirtuin 4 [Homo sapiens] Length = 314 Score = 86.3 bits (212), Expect = 5e-17 Identities = 81/284 (28%), Positives = 129/284 (45%), Gaps = 54/284 (19%) Query: 81 DPEELRGKVRELASAVRNAKYLVVYTGAGISTAASIPDYRGPN-GVWTL-----LQKGRS 134 DPE KV+EL + +K L+V TGAGIST + IPDYR G++ +Q G Sbjct: 40 DPE----KVKELQRFITLSKRLLVMTGAGISTESGIPDYRSEKVGLYARTDRRPIQHGDF 95 Query: 135 VSAADL---------------SEAEPTLTHMSITRLHEQKLVQHVVSQNCDGLHLRSGLP 179 V +A + S +P H +++ + + +V+QN D LH ++G Sbjct: 96 VRSAPIRQRYWARNFVGWPQFSSHQPNPAHWALSTWEKLGKLYWLVTQNVDALHTKAGSR 155 Query: 180 RTAISELHGNMYIEVCTSCVPN------REYVRVFDVTERTALH---------------R 218 R ++ELHG M +C C +E +V + T H R Sbjct: 156 R--LTELHGCMDRVLCLDCGEQTPRGVLQERFQVLNPTWSAEAHGLAPDGDVFLSEEQVR 213 Query: 219 HQTGRTCHKCGTQLRDTIVHFGERGTLGQPLNWEAATEAASRADTILCLGSSLKVLKKYP 278 TC +CG L+ +V FG+ P + + AD++L +GSSL+V Y Sbjct: 214 SFQVPTCVQCGGHLKPDVVFFGD---TVNPDKVDFVHKRVKEADSLLVVGSSLQVYSGY- 269 Query: 279 RLWCMTKPPSRRPKLYIVNLQWTPKDDWAALKLHGKCDDVMRLL 322 + +T + P + I+N+ T DD A LKL+ +C +++ L+ Sbjct: 270 -RFILTAWEKKLP-IAILNIGPTRSDDLACLKLNSRCGELLPLI 311 >gi|6912660 sirtuin 3 isoform a [Homo sapiens] Length = 399 Score = 66.2 bits (160), Expect = 5e-11 Identities = 64/211 (30%), Positives = 93/211 (44%), Gaps = 40/211 (18%) Query: 89 VRELASAVRNAKYLVVYTGAGISTAASIPDYRGP-NGVWTLLQ----------------- 130 V EL A R + +VV GAGIST + IPD+R P +G+++ LQ Sbjct: 128 VAELIRA-RACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFF 186 Query: 131 ---KGRSVSAADL--SEAEPTLTHMSITRLHEQKLVQHVVSQNCDGLHLRSGLPRTAISE 185 K A +L +P +TH + LH++ L+ + +QN DGL SG+P + + E Sbjct: 187 HNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVE 246 Query: 186 LHGNMYIEVCTSC---VPNREYVRVFDVTERTALHRHQTGRTCHKCGTQLRDTIVHFGER 242 HG CT C P E +R + +R C C ++ IV FGE Sbjct: 247 AHGTFASATCTVCQRPFPG-EDIRADVMADRVP--------RCPVCTGVVKPDIVFFGE- 296 Query: 243 GTLGQPLNWEAATEAASRADTILCLGSSLKV 273 P + AD +L LG+SL+V Sbjct: 297 ---PLPQRFLLHVVDFPMADLLLILGTSLEV 324 >gi|13775600 sirtuin 2 isoform 1 [Homo sapiens] Length = 389 Score = 62.0 bits (149), Expect = 9e-10 Identities = 65/252 (25%), Positives = 106/252 (42%), Gaps = 51/252 (20%) Query: 75 QEEVCDDPEELRGKVRELASAVRNAKYLVVYTGAGISTAASIPDYRGPN-GVWTLLQKGR 133 Q+E D L G R + S + ++ GAGIST+A IPD+R P+ G++ L+K Sbjct: 54 QKERLLDELTLEGVARYMQS--ERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYH 111 Query: 134 SVSAADLSEA----------------------EPTLTHMSITRLHEQKLVQHVVSQNCDG 171 + E +PT+ H + L ++ L+ +QN D Sbjct: 112 LPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDT 171 Query: 172 LHLRSGLPRTAISELHGNMYIEVCTSCVPNREY------VRVF-DVTERTALHRHQTGRT 224 L +GL + + E HG Y C S EY ++F +VT + Sbjct: 172 LERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPK----------- 220 Query: 225 CHKCGTQLRDTIVHFGERGTLGQPLNWEAATEA-ASRADTILCLGSSLKVLKKYPRLWCM 283 C C + ++ IV FGE P + + ++ + D +L +G+SL+V P + Sbjct: 221 CEDCQSLVKPDIVFFGE----SLPARFFSCMQSDFLKVDLLLVMGTSLQV---QPFASLI 273 Query: 284 TKPPSRRPKLYI 295 +K P P+L I Sbjct: 274 SKAPLSTPRLLI 285 >gi|13775602 sirtuin 2 isoform 2 [Homo sapiens] Length = 352 Score = 62.0 bits (149), Expect = 9e-10 Identities = 65/252 (25%), Positives = 106/252 (42%), Gaps = 51/252 (20%) Query: 75 QEEVCDDPEELRGKVRELASAVRNAKYLVVYTGAGISTAASIPDYRGPN-GVWTLLQKGR 133 Q+E D L G R + S + ++ GAGIST+A IPD+R P+ G++ L+K Sbjct: 17 QKERLLDELTLEGVARYMQS--ERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYH 74 Query: 134 SVSAADLSEA----------------------EPTLTHMSITRLHEQKLVQHVVSQNCDG 171 + E +PT+ H + L ++ L+ +QN D Sbjct: 75 LPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDT 134 Query: 172 LHLRSGLPRTAISELHGNMYIEVCTSCVPNREY------VRVF-DVTERTALHRHQTGRT 224 L +GL + + E HG Y C S EY ++F +VT + Sbjct: 135 LERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPK----------- 183 Query: 225 CHKCGTQLRDTIVHFGERGTLGQPLNWEAATEA-ASRADTILCLGSSLKVLKKYPRLWCM 283 C C + ++ IV FGE P + + ++ + D +L +G+SL+V P + Sbjct: 184 CEDCQSLVKPDIVFFGE----SLPARFFSCMQSDFLKVDLLLVMGTSLQV---QPFASLI 236 Query: 284 TKPPSRRPKLYI 295 +K P P+L I Sbjct: 237 SKAPLSTPRLLI 248 >gi|63054862 sirtuin 3 isoform b [Homo sapiens] Length = 257 Score = 61.6 bits (148), Expect = 1e-09 Identities = 57/193 (29%), Positives = 84/193 (43%), Gaps = 39/193 (20%) Query: 107 GAGISTAASIPDYRGP-NGVWTLLQ--------------------KGRSVSAADL--SEA 143 GAGIST + IPD+R P +G+++ LQ K A +L Sbjct: 3 GAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNY 62 Query: 144 EPTLTHMSITRLHEQKLVQHVVSQNCDGLHLRSGLPRTAISELHGNMYIEVCTSC---VP 200 +P +TH + LH++ L+ + +QN DGL SG+P + + E HG CT C P Sbjct: 63 KPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFP 122 Query: 201 NREYVRVFDVTERTALHRHQTGRTCHKCGTQLRDTIVHFGERGTLGQPLNWEAATEAASR 260 E +R + +R C C ++ IV FGE P + Sbjct: 123 G-EDIRADVMADRVP--------RCPVCTGVVKPDIVFFGE----PLPQRFLLHVVDFPM 169 Query: 261 ADTILCLGSSLKV 273 AD +L LG+SL+V Sbjct: 170 ADLLLILGTSLEV 182 >gi|6912664 sirtuin 5 isoform 1 [Homo sapiens] Length = 310 Score = 57.4 bits (137), Expect = 2e-08 Identities = 64/258 (24%), Positives = 97/258 (37%), Gaps = 55/258 (21%) Query: 99 AKYLVVYTGAGISTAASIPDYRGPNGVWTLLQKGRSVSAADLS----------------- 141 AK++V+ +GAG+S + +P +RG G W R A DL+ Sbjct: 50 AKHIVIISGAGVSAESGVPTFRGAGGYW------RKWQAQDLATPLAFAHNPSRVWEFYH 103 Query: 142 -------EAEPTLTHMSI----TRLHEQKLVQHVVSQNCDGLHLRSGLPRTAISELHGNM 190 EP H +I TRL +Q V++QN D LH ++G + E+HG++ Sbjct: 104 YRREVMGSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELHRKAGTKN--LLEIHGSL 161 Query: 191 YIEVCTSCVPNREYVRVFDVTERTALHRHQTGR-----------TCHK--CGTQLRDTIV 237 + CTSC E + + + G C + CG LR +V Sbjct: 162 FKTRCTSCGVVAENYKSPICPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGGLLRPHVV 221 Query: 238 HFGERGTLGQPLNWEAATEAASRADTILCLGSSLKVLKKYPRLWCMTKPPSRRPKLYIVN 297 FGE P E + D L +G+S V YP + +R + N Sbjct: 222 WFGEN---LDPAILEEVDRELAHCDLCLVVGTSSVV---YPAAMFAPQVAARGVPVAEFN 275 Query: 298 LQWTPKDDWAALKLHGKC 315 + TP + G C Sbjct: 276 TETTPATNRFRFHFQGPC 293 >gi|13787215 sirtuin 5 isoform 2 [Homo sapiens] Length = 299 Score = 55.1 bits (131), Expect = 1e-07 Identities = 62/245 (25%), Positives = 94/245 (38%), Gaps = 55/245 (22%) Query: 99 AKYLVVYTGAGISTAASIPDYRGPNGVWTLLQKGRSVSAADLS----------------- 141 AK++V+ +GAG+S + +P +RG G W R A DL+ Sbjct: 50 AKHIVIISGAGVSAESGVPTFRGAGGYW------RKWQAQDLATPLAFAHNPSRVWEFYH 103 Query: 142 -------EAEPTLTHMSI----TRLHEQKLVQHVVSQNCDGLHLRSGLPRTAISELHGNM 190 EP H +I TRL +Q V++QN D LH ++G + E+HG++ Sbjct: 104 YRREVMGSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELHRKAGTKN--LLEIHGSL 161 Query: 191 YIEVCTSCVPNREYVRVFDVTERTALHRHQTGR-----------TCHK--CGTQLRDTIV 237 + CTSC E + + + G C + CG LR +V Sbjct: 162 FKTRCTSCGVVAENYKSPICPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGGLLRPHVV 221 Query: 238 HFGERGTLGQPLNWEAATEAASRADTILCLGSSLKVLKKYPRLWCMTKPPSRRPKLYIVN 297 FGE P E + D L +G+S V YP + +R + N Sbjct: 222 WFGEN---LDPAILEEVDRELAHCDLCLVVGTSSVV---YPAAMFAPQVAARGVPVAEFN 275 Query: 298 LQWTP 302 + TP Sbjct: 276 TETTP 280 >gi|7657575 sirtuin 1 isoform a [Homo sapiens] Length = 747 Score = 45.8 bits (107), Expect = 7e-05 Identities = 65/278 (23%), Positives = 111/278 (39%), Gaps = 61/278 (21%) Query: 89 VRELASAVRNAKYLVVYTGAGISTAASIPDYRGPNGVWTLLQKGRSVSAADL-------- 140 + + ++ K ++V TGAG+S + IPD+R +G++ L +V DL Sbjct: 243 IEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARL----AVDFPDLPDPQAMFD 298 Query: 141 --------------------SEAEPTLTHMSITRLHEQKLVQHVVSQNCDGLHLRSGLPR 180 + +P+L H I ++ + +QN D L +G+ R Sbjct: 299 IEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQR 358 Query: 181 TAISELHGNMYIEVCTSC--VPNREYVR--VFDVTERTALHRHQTGRTCHKCGTQ----- 231 I + HG+ C C + E VR +F +Q C +C Sbjct: 359 --IIQCHGSFATASCLICKYKVDCEAVRGDIF----------NQVVPRCPRCPADEPLAI 406 Query: 232 LRDTIVHFGERGTLGQPLNWEAATEAASRADTILCLGSSLKVLKKYPRLWCMTKPPSRRP 291 ++ IV FGE L + + A D ++ +GSSLKV P + P P Sbjct: 407 MKPEIVFFGE--NLPEQFH-RAMKYDKDEVDLLIVIGSSLKV---RPVALIPSSIPHEVP 460 Query: 292 KLYIVNLQWTPKDDWAALKLHGKCDDVMRLLMAELGLE 329 ++ ++N + P + ++L G CD ++ L LG E Sbjct: 461 QI-LINREPLPHLHF-DVELLGDCDVIINELCHRLGGE 496 >gi|239756174 PREDICTED: hypothetical protein [Homo sapiens] Length = 625 Score = 40.4 bits (93), Expect = 0.003 Identities = 34/99 (34%), Positives = 49/99 (49%), Gaps = 14/99 (14%) Query: 4 GGLSRSERKAAERVRRL--REEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTEL 61 G R ER+AA R +R R E++R L + +LR+ AER+A E RL + + Sbjct: 419 GRRGREEREAARRRQRQYERSEERRRELAERQGLLRRERAERAAREDRLRK-----LQQE 473 Query: 62 QGRSRRREGLKRRQEEVCDDPEELRGKVRELASAVRNAK 100 Q +R EGL+ +E E++R RE A AK Sbjct: 474 QNLKQREEGLQEGRERA----EQIR---RERAQRAARAK 505 >gi|239750672 PREDICTED: hypothetical protein [Homo sapiens] Length = 627 Score = 40.4 bits (93), Expect = 0.003 Identities = 34/99 (34%), Positives = 49/99 (49%), Gaps = 14/99 (14%) Query: 4 GGLSRSERKAAERVRRL--REEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTEL 61 G R ER+AA R +R R E++R L + +LR+ AER+A E RL + + Sbjct: 421 GRRGREEREAARRRQRQYERSEERRRELAERQGLLRRERAERAAREDRLRK-----LQQE 475 Query: 62 QGRSRRREGLKRRQEEVCDDPEELRGKVRELASAVRNAK 100 Q +R EGL+ +E E++R RE A AK Sbjct: 476 QNLKQREEGLQEGRERA----EQIR---RERAQRAARAK 507 >gi|239744982 PREDICTED: hypothetical protein [Homo sapiens] Length = 627 Score = 40.4 bits (93), Expect = 0.003 Identities = 34/99 (34%), Positives = 49/99 (49%), Gaps = 14/99 (14%) Query: 4 GGLSRSERKAAERVRRL--REEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTEL 61 G R ER+AA R +R R E++R L + +LR+ AER+A E RL + + Sbjct: 421 GRRGREEREAARRRQRQYERSEERRRELAERQGLLRRERAERAAREDRLRK-----LQQE 475 Query: 62 QGRSRRREGLKRRQEEVCDDPEELRGKVRELASAVRNAK 100 Q +R EGL+ +E E++R RE A AK Sbjct: 476 QNLKQREEGLQEGRERA----EQIR---RERAQRAARAK 507 >gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens] Length = 570 Score = 38.9 bits (89), Expect = 0.008 Identities = 24/86 (27%), Positives = 48/86 (55%), Gaps = 6/86 (6%) Query: 6 LSRSERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTELQGRS 65 + R E K E+ +++RE Q E++R+ ++++ + +EG++ + A + E + + Sbjct: 434 MRRQEEKIREQEKKIRE--QEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKM-QEQEEKM 490 Query: 66 RRREGLKRRQEEVCDDPEELRGKVRE 91 RR+E R QE+ + EE K+RE Sbjct: 491 RRQEEKIREQEKKIREQEE---KIRE 513 Score = 30.8 bits (68), Expect = 2.3 Identities = 21/90 (23%), Positives = 46/90 (51%), Gaps = 8/90 (8%) Query: 6 LSRSERKAAERVRRLREEQ----QRERLRQVSRILRKAAAERSAEEGRLLAESADLVTEL 61 + E++ + + R+E+ Q E++R+ ++++ E+ E+ + E + + E Sbjct: 372 IREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQE-EKMGEQEEKMWEQEEEMQEQ 430 Query: 62 QGRSRRREGLKRRQEEVCDDPEELRGKVRE 91 + + RR+E R QE+ + EE K+RE Sbjct: 431 EEKMRRQEEKIREQEKKIREQEE---KIRE 457 >gi|148806928 hypothetical protein LOC57482 [Homo sapiens] Length = 1233 Score = 38.9 bits (89), Expect = 0.008 Identities = 33/97 (34%), Positives = 46/97 (47%), Gaps = 17/97 (17%) Query: 1 MAAGGLSRSERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTE 60 + A G +ER+ E RL E++R RL+ A+ AEE R L E A L E Sbjct: 295 LEAPGWEDAERREREERERLEAEEERRRLQ----------AQAQAEERRRLEEDARL--E 342 Query: 61 LQGRSRRREG-----LKRRQEEVCDDPEELRGKVREL 92 + R EG LKR++EE + EEL + E+ Sbjct: 343 ERRRQEEEEGRCAEELKRQEEEEAEGWEELEQQEAEV 379 >gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] Length = 793 Score = 38.5 bits (88), Expect = 0.011 Identities = 26/88 (29%), Positives = 46/88 (52%), Gaps = 6/88 (6%) Query: 9 SERKAAERVRRLREEQQRERLRQVSRILRKAAAERS--AEEGRLLAESADLVTELQGR-S 65 +E KAA + R RE ++RER+R+ ++AA ER EE + AE + E + R + Sbjct: 297 AEEKAAAQERERREAEERERMREEE---KRAAEERQRIKEEEKRAAEERQRIKEEEKRAA 353 Query: 66 RRREGLKRRQEEVCDDPEELRGKVRELA 93 R+ +K ++ ++ + R + E A Sbjct: 354 EERQRIKEEEKRAAEERQRARAEEEEKA 381 Score = 34.3 bits (77), Expect = 0.20 Identities = 29/94 (30%), Positives = 46/94 (48%), Gaps = 6/94 (6%) Query: 3 AGGLSRSERKAAERVRRLREEQQR--ERLRQVSRILRKAAAERS--AEEGRLLAESADLV 58 A R R+A ER R+REE++R E +++ ++AA ER EE + AE + Sbjct: 301 AAAQERERREAEER-ERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRI 359 Query: 59 TELQGR-SRRREGLKRRQEEVCDDPEELRGKVRE 91 E + R + R+ + +EE E+ R K E Sbjct: 360 KEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLE 393 Score = 30.0 bits (66), Expect = 3.9 Identities = 27/112 (24%), Positives = 48/112 (42%), Gaps = 21/112 (18%) Query: 10 ERKAAERVRRLREEQQRERLRQVSRIL---------RKAAA-----------ERSAEEGR 49 ER AER R EE++R + Q +I KAAA ER EE + Sbjct: 263 ERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEK 322 Query: 50 LLAESADLVTELQGR-SRRREGLKRRQEEVCDDPEELRGKVRELASAVRNAK 100 AE + E + R + R+ +K ++ ++ + ++ + + A + A+ Sbjct: 323 RAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRAR 374 Score = 28.9 bits (63), Expect = 8.6 Identities = 14/33 (42%), Positives = 21/33 (63%) Query: 11 RKAAERVRRLREEQQRERLRQVSRILRKAAAER 43 RK E R+LREE+++ RL++ R AAE+ Sbjct: 586 RKQEEADRKLREEEEKRRLKEEIERRRAEAAEK 618 >gi|4505101 microtubule-associated protein 7 [Homo sapiens] Length = 749 Score = 38.1 bits (87), Expect = 0.014 Identities = 30/102 (29%), Positives = 50/102 (49%), Gaps = 10/102 (9%) Query: 9 SERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEE---------GRLLAESA-DLV 58 +E++ R +R +EE++R ++ R R+ A+R AEE RL AE A + Sbjct: 484 AEKRRLAREQREKEERERREQEELERQKREELAQRVAEERTTRREEESRRLEAEQAREKE 543 Query: 59 TELQGRSRRREGLKRRQEEVCDDPEELRGKVRELASAVRNAK 100 +LQ ++ R +R + E +E +VRE A VR + Sbjct: 544 EQLQRQAEERALREREEAERAQRQKEEEARVREEAERVRQER 585 Score = 30.0 bits (66), Expect = 3.9 Identities = 20/68 (29%), Positives = 34/68 (50%), Gaps = 2/68 (2%) Query: 10 ERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTELQGRSRRRE 69 ER+ AER +R +EE+ R R + R+ ++ EE L E + E+ R+RR E Sbjct: 557 EREEAERAQRQKEEEARVR-EEAERVRQEREKHFQREEQERL-ERKKRLEEIMKRTRRTE 614 Query: 70 GLKRRQEE 77 ++ + Sbjct: 615 ATDKKTSD 622 Score = 28.9 bits (63), Expect = 8.6 Identities = 24/78 (30%), Positives = 34/78 (43%), Gaps = 14/78 (17%) Query: 15 ERVRRLREEQQRERLRQVSRILRKAA---------AERSAEEGRLLAESADLVTE----- 60 E RRL EQ RE+ Q+ R + A A+R EE + E A+ V + Sbjct: 529 EESRRLEAEQAREKEEQLQRQAEERALREREEAERAQRQKEEEARVREEAERVRQEREKH 588 Query: 61 LQGRSRRREGLKRRQEEV 78 Q + R K+R EE+ Sbjct: 589 FQREEQERLERKKRLEEI 606 >gi|148746195 trichohyalin [Homo sapiens] Length = 1943 Score = 37.7 bits (86), Expect = 0.019 Identities = 28/83 (33%), Positives = 45/83 (54%), Gaps = 3/83 (3%) Query: 6 LSRSERKAAERVRRLREEQQRERLRQVSRILRKAAAER--SAEEGRLLAESADLVTELQG 63 L + ER+ R R+ E+QQ +RLR+ ++ RK ER EE R E + E + Sbjct: 278 LRKLERQELRRERQEEEQQQ-QRLRREQQLRRKQEEERREQQEERREQQERREQQEERRE 336 Query: 64 RSRRREGLKRRQEEVCDDPEELR 86 + RRE +RR++++ + EE R Sbjct: 337 QQLRREQEERREQQLRREQEEER 359 Score = 36.6 bits (83), Expect = 0.041 Identities = 26/80 (32%), Positives = 47/80 (58%), Gaps = 4/80 (5%) Query: 15 ERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADL--VTELQGRSRRREGLK 72 E + LREE+++ RL++ R R+ E EE +LL E + EL+ + R+ E L+ Sbjct: 1029 EEEQLLREEREKRRLQERERQYRE-EEELQQEEEQLLGEERETRRRQELERQYRKEEELQ 1087 Query: 73 RRQEEVC-DDPEELRGKVRE 91 + +E++ ++PE+ R + RE Sbjct: 1088 QEEEQLLREEPEKRRRQERE 1107 Score = 33.9 bits (76), Expect = 0.27 Identities = 24/68 (35%), Positives = 36/68 (52%), Gaps = 4/68 (5%) Query: 10 ERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTELQGRSRRRE 69 E + ER +L EE++RE+ + + LR+ ER E RL + + LQ R R + Sbjct: 481 EEERRERWLKLEEEERREQQERREQQLRREQEER--REQRLKRQEEE--ERLQQRLRSEQ 536 Query: 70 GLKRRQEE 77 L+R QEE Sbjct: 537 QLRREQEE 544 Score = 33.9 bits (76), Expect = 0.27 Identities = 25/89 (28%), Positives = 43/89 (48%), Gaps = 8/89 (8%) Query: 6 LSRSERKAAERVRRLREE--------QQRERLRQVSRILRKAAAERSAEEGRLLAESADL 57 L R E + +R++R +EE ++ ERL Q R ++ E EE R ++ Sbjct: 579 LKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEE 638 Query: 58 VTELQGRSRRREGLKRRQEEVCDDPEELR 86 E + + RRE +RR++ + + EE R Sbjct: 639 QEERRQQQLRREQQERREQRLKREEEEER 667 Score = 33.9 bits (76), Expect = 0.27 Identities = 25/100 (25%), Positives = 49/100 (49%), Gaps = 8/100 (8%) Query: 10 ERKAAERVRRLREEQQRER-----LRQVSRILRKAAAERSAEEGRLLAESADLVTELQGR 64 +R+ ER R+ REE++ ++ LR+ R+ ER E + + + + + Sbjct: 1100 KRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPE 1159 Query: 65 SRRREGLKRR---QEEVCDDPEELRGKVRELASAVRNAKY 101 RRR+ L+R+ +EE+ + E+L + +E R +Y Sbjct: 1160 KRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQY 1199 Score = 33.1 bits (74), Expect = 0.46 Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 11/88 (12%) Query: 8 RSERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTELQGRSRR 67 R +RK+ E + LREE++ +R RQ + EE +LL E + Q R R+ Sbjct: 1309 RRDRKSQEEKQLLREEREEKRRRQ-------ETDRKFREEEQLLQEREEQPLRRQERDRK 1361 Query: 68 -REGLKRRQEE---VCDDPEELRGKVRE 91 RE R QE+ ++ + LR + RE Sbjct: 1362 FREEELRHQEQGRKFLEEEQRLRRQERE 1389 Score = 32.7 bits (73), Expect = 0.60 Identities = 24/92 (26%), Positives = 46/92 (50%), Gaps = 8/92 (8%) Query: 8 RSERKAAERVRRLREEQQRER-----LRQVSRILRKAAAERSAEEGRLLAESADLVTELQ 62 R +R+ E+ R+ REE+Q ++ LR+ R+ ER + + L + + + + Sbjct: 918 REKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEE 977 Query: 63 GRSRRREGLK---RRQEEVCDDPEELRGKVRE 91 RRR+ + R +EE+ + E+L + RE Sbjct: 978 PEKRRRQEREKKYREEEELQQEEEQLLREERE 1009 Score = 32.7 bits (73), Expect = 0.60 Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 6/81 (7%) Query: 11 RKAAERVRRLREEQQRER---LRQVSRILRKAAAERSAEEGRLLAESADLVTELQGRSRR 67 R+ ER R EE Q+E LR+ R+ ER E L + + + + RR Sbjct: 1073 RQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRR 1132 Query: 68 REGLKRR---QEEVCDDPEEL 85 R+ L+R+ +EEV + E+L Sbjct: 1133 RQELERQYREEEEVQQEEEQL 1153 Score = 32.3 bits (72), Expect = 0.78 Identities = 20/62 (32%), Positives = 33/62 (53%), Gaps = 3/62 (4%) Query: 16 RVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTELQGRSRRREGLKRRQ 75 R +RL+ +++ ERL+Q R ++ E+ +LL + E + RR + LKR Q Sbjct: 515 REQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLE---QERREQRLKREQ 571 Query: 76 EE 77 EE Sbjct: 572 EE 573 Score = 32.0 bits (71), Expect = 1.0 Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 18/105 (17%) Query: 5 GLSRSERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEG---RLLAESADLVTEL 61 G +++ ER R+ +E++ + R+ +LRK + EE R L E + + +L Sbjct: 222 GREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKL 281 Query: 62 ---------------QGRSRRREGLKRRQEEVCDDPEELRGKVRE 91 Q R RR + L+R+QEE + +E R + +E Sbjct: 282 ERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQE 326 Score = 31.6 bits (70), Expect = 1.3 Identities = 24/97 (24%), Positives = 47/97 (48%), Gaps = 12/97 (12%) Query: 5 GLSRSERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTELQGR 64 G +R+ ER ++ REE++ ++ + ++LR+ +R +E D + + + + Sbjct: 975 GEEPEKRRRQEREKKYREEEELQQ--EEEQLLREEREKRRRQEWERQYRKKDELQQEEEQ 1032 Query: 65 SRRREGLKRR----------QEEVCDDPEELRGKVRE 91 R E KRR +EE+ + E+L G+ RE Sbjct: 1033 LLREEREKRRLQERERQYREEEELQQEEEQLLGEERE 1069 Score = 31.2 bits (69), Expect = 1.7 Identities = 20/73 (27%), Positives = 43/73 (58%), Gaps = 7/73 (9%) Query: 10 ERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAE-----EGRLLAESADLVTELQGR 64 E + +R++R EE++RE+ +++ ++ A ER + +L +E+ +++ R Sbjct: 665 EERLEQRLKREHEEERREQ--ELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSR 722 Query: 65 SRRREGLKRRQEE 77 R++EG +RRQE+ Sbjct: 723 PRKQEGQRRRQEQ 735 Score = 30.8 bits (68), Expect = 2.3 Identities = 23/92 (25%), Positives = 45/92 (48%), Gaps = 8/92 (8%) Query: 8 RSERKAAERVRRLREEQQRER-----LRQVSRILRKAAAERSAEEGRLLAESADLVTELQ 62 R +R+ ER R+ REE++ ++ L + R+ ER + L + + + + Sbjct: 1038 REKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREE 1097 Query: 63 GRSRRREGLKRR---QEEVCDDPEELRGKVRE 91 RRR+ +R+ +EE+ + E+L + RE Sbjct: 1098 PEKRRRQERERQCREEEELQQEEEQLLREERE 1129 Score = 30.0 bits (66), Expect = 3.9 Identities = 20/82 (24%), Positives = 41/82 (50%), Gaps = 1/82 (1%) Query: 10 ERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTELQGRSRRRE 69 +RK E ++LR +++ + Q + LR+ ER E L + + +L+ + R R+ Sbjct: 1690 DRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETE-QEQLRRQERYRK 1748 Query: 70 GLKRRQEEVCDDPEELRGKVRE 91 L+ Q + ++LR + R+ Sbjct: 1749 ILEEEQLRPEREEQQLRRQERD 1770 Score = 29.6 bits (65), Expect = 5.0 Identities = 22/87 (25%), Positives = 48/87 (55%), Gaps = 4/87 (4%) Query: 8 RSERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTELQGRSRR 67 RS+ + ++ R + E++R+R R+ + + A E+ +E +LL E + + + RR Sbjct: 864 RSQEQRRDQKWRWQLEEERKR-RRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRR 922 Query: 68 REGLKRR---QEEVCDDPEELRGKVRE 91 R+ +R+ +E++ + E+L + RE Sbjct: 923 RQEQERQYREEEQLQQEEEQLLREERE 949 Score = 29.3 bits (64), Expect = 6.6 Identities = 24/77 (31%), Positives = 40/77 (51%), Gaps = 7/77 (9%) Query: 8 RSERKAAERVRRLREEQQRE-RLRQVSRILRKAAAERSAEEGR--LLAESADLVTELQGR 64 + E + +++RR +EE++RE +LR+ ++ R+ R + R L L E Q R Sbjct: 355 QEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 414 Query: 65 S----RRREGLKRRQEE 77 RR + L+R QEE Sbjct: 415 REQQLRREQQLRREQEE 431 Score = 29.3 bits (64), Expect = 6.6 Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 6/73 (8%) Query: 10 ERKAAERVRRLREEQQ-RERLRQVSRILRKAAAERS-----AEEGRLLAESADLVTELQG 63 E + +R++R EE++ ++RLR ++ R+ R EE RL E + + + Sbjct: 512 EERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQ 571 Query: 64 RSRRREGLKRRQE 76 RR + LKR +E Sbjct: 572 EERRDQLLKREEE 584 Score = 28.9 bits (63), Expect = 8.6 Identities = 21/84 (25%), Positives = 37/84 (44%), Gaps = 2/84 (2%) Query: 10 ERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAE--EGRLLAESADLVTELQGRSRR 67 +R+ E R+ +E Q+RE R L+ + E + L L +GR + Sbjct: 167 QRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEK 226 Query: 68 REGLKRRQEEVCDDPEELRGKVRE 91 ++ + RQ+ V + EE + RE Sbjct: 227 QQQRRERQDRVFQEEEEKEWRKRE 250 Score = 28.9 bits (63), Expect = 8.6 Identities = 20/79 (25%), Positives = 36/79 (45%), Gaps = 7/79 (8%) Query: 6 LSRSERKAAERVRRLREEQQRERLRQVSRILRKAAAER-------SAEEGRLLAESADLV 58 L R + + + ++R E ++ E+ R+ ++ R ER EE R E + Sbjct: 447 LKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQ 506 Query: 59 TELQGRSRRREGLKRRQEE 77 + RR + LKR++EE Sbjct: 507 LRREQEERREQRLKRQEEE 525 Score = 28.9 bits (63), Expect = 8.6 Identities = 25/78 (32%), Positives = 39/78 (50%), Gaps = 7/78 (8%) Query: 8 RSERKAAERVRRLREEQQRER-----LRQVSRILRKAAAERS-AEEGRLLAESADLVTEL 61 R +R+ E R+ REE++ ++ LR+ R+ ER EE L E L+ E Sbjct: 1128 REKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREE 1187 Query: 62 QGRSRR-REGLKRRQEEV 78 Q + R+ RE R +EE+ Sbjct: 1188 QEKRRQERERQYREEEEL 1205 >gi|62244004 modulator of estrogen induced transcription isoform b [Homo sapiens] Length = 1016 Score = 37.4 bits (85), Expect = 0.024 Identities = 25/86 (29%), Positives = 46/86 (53%), Gaps = 7/86 (8%) Query: 6 LSRSERKAAERVRRLREEQQRERL-RQVSRI------LRKAAAERSAEEGRLLAESADLV 58 ++ ER+ ER+R +RE ++RERL R+ R+ L + ER E + + Sbjct: 619 IAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERR 678 Query: 59 TELQGRSRRREGLKRRQEEVCDDPEE 84 E + +R RE L+R+Q+++ + E+ Sbjct: 679 KEAERIAREREELRRQQQQLRYEQEK 704 >gi|63176611 modulator of estrogen induced transcription isoform a [Homo sapiens] Length = 1034 Score = 37.4 bits (85), Expect = 0.024 Identities = 25/86 (29%), Positives = 46/86 (53%), Gaps = 7/86 (8%) Query: 6 LSRSERKAAERVRRLREEQQRERL-RQVSRI------LRKAAAERSAEEGRLLAESADLV 58 ++ ER+ ER+R +RE ++RERL R+ R+ L + ER E + + Sbjct: 637 IAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERR 696 Query: 59 TELQGRSRRREGLKRRQEEVCDDPEE 84 E + +R RE L+R+Q+++ + E+ Sbjct: 697 KEAERIAREREELRRQQQQLRYEQEK 722 >gi|102467235 inner centromere protein antigens 135/155kDa isoform 1 [Homo sapiens] Length = 918 Score = 37.4 bits (85), Expect = 0.024 Identities = 30/98 (30%), Positives = 50/98 (51%), Gaps = 12/98 (12%) Query: 6 LSRSER-----KAAERVRRLREEQQR---ERLRQVSRILRKAAAERSAEEGRLLAESADL 57 L R ER +A ERV +++EE+++ ++ Q+ KA ER AEE +A Sbjct: 572 LKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKK 631 Query: 58 VTELQGRSRRREGLKR----RQEEVCDDPEELRGKVRE 91 + E++ R ++ E +R +QEE +EL K +E Sbjct: 632 MEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKE 669 Score = 36.2 bits (82), Expect = 0.054 Identities = 31/94 (32%), Positives = 40/94 (42%), Gaps = 12/94 (12%) Query: 9 SERKAAERVRRLREEQQRERLRQVSRILRKAAAE-----RSAEEGRLLAESADLVTELQG 63 + RK E RRLR QQ E R+ +L+K E R A E + LAE + Q Sbjct: 637 ARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQE 696 Query: 64 R-------SRRREGLKRRQEEVCDDPEELRGKVR 90 R RRE +R QE + E R + R Sbjct: 697 RREQERREQERREQERREQERQLAEQERRREQER 730 Score = 34.3 bits (77), Expect = 0.20 Identities = 30/89 (33%), Positives = 46/89 (51%), Gaps = 12/89 (13%) Query: 8 RSERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTELQGRSR- 66 R E++ E+ RR +E +++ER Q ++ A ER E+ RL AE ELQ R + Sbjct: 692 RREQERREQERREQERREQERREQERQL---AEQERRREQERLQAE-----RELQEREKA 743 Query: 67 ---RREGLKRRQEEVCDDPEELRGKVREL 92 ++E L+R EE E+ R R+L Sbjct: 744 LRLQKEQLQRELEEKKKKEEQQRLAERQL 772 >gi|102467242 inner centromere protein antigens 135/155kDa isoform 2 [Homo sapiens] Length = 914 Score = 37.4 bits (85), Expect = 0.024 Identities = 30/98 (30%), Positives = 50/98 (51%), Gaps = 12/98 (12%) Query: 6 LSRSER-----KAAERVRRLREEQQR---ERLRQVSRILRKAAAERSAEEGRLLAESADL 57 L R ER +A ERV +++EE+++ ++ Q+ KA ER AEE +A Sbjct: 568 LKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKK 627 Query: 58 VTELQGRSRRREGLKR----RQEEVCDDPEELRGKVRE 91 + E++ R ++ E +R +QEE +EL K +E Sbjct: 628 MEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKE 665 Score = 36.2 bits (82), Expect = 0.054 Identities = 31/94 (32%), Positives = 40/94 (42%), Gaps = 12/94 (12%) Query: 9 SERKAAERVRRLREEQQRERLRQVSRILRKAAAE-----RSAEEGRLLAESADLVTELQG 63 + RK E RRLR QQ E R+ +L+K E R A E + LAE + Q Sbjct: 633 ARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQE 692 Query: 64 R-------SRRREGLKRRQEEVCDDPEELRGKVR 90 R RRE +R QE + E R + R Sbjct: 693 RREQERREQERREQERREQERQLAEQERRREQER 726 Score = 34.3 bits (77), Expect = 0.20 Identities = 30/89 (33%), Positives = 46/89 (51%), Gaps = 12/89 (13%) Query: 8 RSERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTELQGRSR- 66 R E++ E+ RR +E +++ER Q ++ A ER E+ RL AE ELQ R + Sbjct: 688 RREQERREQERREQERREQERREQERQL---AEQERRREQERLQAE-----RELQEREKA 739 Query: 67 ---RREGLKRRQEEVCDDPEELRGKVREL 92 ++E L+R EE E+ R R+L Sbjct: 740 LRLQKEQLQRELEEKKKKEEQQRLAERQL 768 >gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] Length = 1564 Score = 37.0 bits (84), Expect = 0.032 Identities = 32/89 (35%), Positives = 43/89 (48%), Gaps = 5/89 (5%) Query: 6 LSRSERKAAERVRRL---REEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTELQ 62 L R ER+ RV R+ R+E+ RER R+ R R+ ER E R + +L E + Sbjct: 654 LERDERREERRVDRVDDRRDERARERDRERERD-RERERERERERDREREKERELERE-R 711 Query: 63 GRSRRREGLKRRQEEVCDDPEELRGKVRE 91 R R RE K R E D + R + RE Sbjct: 712 AREREREREKERDRERDRDRDHDRERERE 740 Score = 31.6 bits (70), Expect = 1.3 Identities = 24/73 (32%), Positives = 37/73 (50%), Gaps = 5/73 (6%) Query: 10 ERKAAERVRRLREEQQRERLRQVSRIL-RKAAAERSAEEGRLLAESADLVTELQGRSRRR 68 ER + R REE++RER R+ R R+ ER+ E + D + +GR RR Sbjct: 742 ERDREKEREREREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRR 801 Query: 69 EGLKRRQEEVCDD 81 E ++EE+ +D Sbjct: 802 E----KREEIRED 810 >gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 123 Score = 36.6 bits (83), Expect = 0.041 Identities = 21/84 (25%), Positives = 45/84 (53%), Gaps = 1/84 (1%) Query: 8 RSERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTELQGRSRR 67 + ++K + + +E+++ E+ R+ R +K ER EE E + E +GR R+ Sbjct: 40 KEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKE-EGRRRK 98 Query: 68 REGLKRRQEEVCDDPEELRGKVRE 91 ++ +RR+EE + ++ R K ++ Sbjct: 99 KKKKRRRKEEEEEKKKKRRRKTKK 122 >gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] Length = 1317 Score = 36.6 bits (83), Expect = 0.041 Identities = 27/92 (29%), Positives = 47/92 (51%), Gaps = 6/92 (6%) Query: 11 RKAAERVRRLREEQQRERL-RQVSRILRK-AAAERSAEEGRLLAESADLVTELQGRSRRR 68 RK + + RE+QQRE L R ++R+ R+ +A +R + G + E + L SR + Sbjct: 987 RKKEKEILESREKQQREALERALARLERRHSALQRHSTLGMEIEEQRQKLASLNSGSREQ 1046 Query: 69 EG----LKRRQEEVCDDPEELRGKVRELASAV 96 G L+ QE + D E L ++++L + Sbjct: 1047 SGLQASLEAEQEALEKDQERLEYEIQQLKQKI 1078 >gi|111955162 5-azacytidine induced 1 isoform b [Homo sapiens] Length = 1044 Score = 36.6 bits (83), Expect = 0.041 Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 17/95 (17%) Query: 9 SERKAAERVRRLREEQQRE--RLRQVSRILRKAAAERSAEEGRLLAESADLVTELQGRSR 66 SE+ A R++RLR++ + E L Q R L++ +E + G E +G + Sbjct: 879 SEKAAESRIKRLRDKYEAELSELEQSERKLQERCSELKGQLG-----------EAEGENL 927 Query: 67 RREGLKRRQEEVCDDP----EELRGKVRELASAVR 97 R +GL R++E +D E+L + LA +R Sbjct: 928 RLQGLVRQKERALEDAQAVNEQLSSERSNLAQVIR 962 Score = 32.3 bits (72), Expect = 0.78 Identities = 24/85 (28%), Positives = 41/85 (48%), Gaps = 9/85 (10%) Query: 15 ERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTELQGRSRRREGLKRR 74 + VRRL+ + E L+ R A++R + L E + E G+ R +R+ Sbjct: 721 QEVRRLKSLHEAELLQSDER-----ASQRCLRQAEELREQLEREKEALGQQERERARQRQ 775 Query: 75 QEEVCDDPEELRGKVRELASAVRNA 99 + E+ EELR ++ E +SA+ A Sbjct: 776 RAEL----EELRQQLEESSSALTRA 796 >gi|111955084 5-azacytidine induced 1 isoform a [Homo sapiens] Length = 1080 Score = 36.6 bits (83), Expect = 0.041 Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 17/95 (17%) Query: 9 SERKAAERVRRLREEQQRE--RLRQVSRILRKAAAERSAEEGRLLAESADLVTELQGRSR 66 SE+ A R++RLR++ + E L Q R L++ +E + G E +G + Sbjct: 915 SEKAAESRIKRLRDKYEAELSELEQSERKLQERCSELKGQLG-----------EAEGENL 963 Query: 67 RREGLKRRQEEVCDDP----EELRGKVRELASAVR 97 R +GL R++E +D E+L + LA +R Sbjct: 964 RLQGLVRQKERALEDAQAVNEQLSSERSNLAQVIR 998 >gi|191252814 RIMS binding protein 3B [Homo sapiens] Length = 1639 Score = 36.2 bits (82), Expect = 0.054 Identities = 31/104 (29%), Positives = 49/104 (47%), Gaps = 3/104 (2%) Query: 5 GLSRSERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAE-SADLVTELQG 63 G R+ A R R+LREE +RER + R+ K A+RS E +L E + E++ Sbjct: 46 GWRAERRRFAARERQLREEAERERRQLADRLRSKWEAQRSRELRQLQEEMQREREAEIRQ 105 Query: 64 RSRRREGLKRRQEEVCDDPEELRGKVRELASAVRNAKYLVVYTG 107 R +E +R+ +++ E G VR+ R +V G Sbjct: 106 LLRWKEAEQRQLQQLLH--RERDGVVRQARELQRQLAEELVNRG 147 >gi|191252806 RIMS binding protein 3C [Homo sapiens] Length = 1639 Score = 36.2 bits (82), Expect = 0.054 Identities = 31/104 (29%), Positives = 49/104 (47%), Gaps = 3/104 (2%) Query: 5 GLSRSERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAE-SADLVTELQG 63 G R+ A R R+LREE +RER + R+ K A+RS E +L E + E++ Sbjct: 46 GWRAERRRFAARERQLREEAERERRQLADRLRSKWEAQRSRELRQLQEEMQREREAEIRQ 105 Query: 64 RSRRREGLKRRQEEVCDDPEELRGKVRELASAVRNAKYLVVYTG 107 R +E +R+ +++ E G VR+ R +V G Sbjct: 106 LLRWKEAEQRQLQQLLH--RERDGVVRQARELQRQLAEELVNRG 147 >gi|153792195 DKFZP434H0735 protein [Homo sapiens] Length = 1639 Score = 36.2 bits (82), Expect = 0.054 Identities = 31/104 (29%), Positives = 49/104 (47%), Gaps = 3/104 (2%) Query: 5 GLSRSERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAE-SADLVTELQG 63 G R+ A R R+LREE +RER + R+ K A+RS E +L E + E++ Sbjct: 46 GWRAERRRFAARERQLREEAERERRQLADRLRSKWEAQRSRELRQLQEEMQREREAEIRQ 105 Query: 64 RSRRREGLKRRQEEVCDDPEELRGKVRELASAVRNAKYLVVYTG 107 R +E +R+ +++ E G VR+ R +V G Sbjct: 106 LLRWKEAEQRQLQQLLH--RERDGVVRQARELQRQLAEELVNRG 147 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.133 0.399 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,763,329 Number of Sequences: 37866 Number of extensions: 730163 Number of successful extensions: 4283 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 102 Number of HSP's successfully gapped in prelim test: 139 Number of HSP's that attempted gapping in prelim test: 3447 Number of HSP's gapped (non-prelim): 792 length of query: 400 length of database: 18,247,518 effective HSP length: 104 effective length of query: 296 effective length of database: 14,309,454 effective search space: 4235598384 effective search space used: 4235598384 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.