Guide to the Human Genome
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Search of human proteins with 7706712

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7706712 sirtuin 7 [Homo sapiens]
         (400 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7706712 sirtuin 7 [Homo sapiens]                                   808   0.0  
gi|7706710 sirtuin 6 [Homo sapiens]                                   177   2e-44
gi|6912662 sirtuin 4 [Homo sapiens]                                    86   5e-17
gi|6912660 sirtuin 3 isoform a [Homo sapiens]                          66   5e-11
gi|13775600 sirtuin 2 isoform 1 [Homo sapiens]                         62   9e-10
gi|13775602 sirtuin 2 isoform 2 [Homo sapiens]                         62   9e-10
gi|63054862 sirtuin 3 isoform b [Homo sapiens]                         62   1e-09
gi|6912664 sirtuin 5 isoform 1 [Homo sapiens]                          57   2e-08
gi|13787215 sirtuin 5 isoform 2 [Homo sapiens]                         55   1e-07
gi|7657575 sirtuin 1 isoform a [Homo sapiens]                          46   7e-05
gi|239756174 PREDICTED: hypothetical protein [Homo sapiens]            40   0.003
gi|239750672 PREDICTED: hypothetical protein [Homo sapiens]            40   0.003
gi|239744982 PREDICTED: hypothetical protein [Homo sapiens]            40   0.003
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap...    39   0.008
gi|148806928 hypothetical protein LOC57482 [Homo sapiens]              39   0.008
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]                       39   0.011
gi|4505101 microtubule-associated protein 7 [Homo sapiens]             38   0.014
gi|148746195 trichohyalin [Homo sapiens]                               38   0.019
gi|62244004 modulator of estrogen induced transcription isoform ...    37   0.024
gi|63176611 modulator of estrogen induced transcription isoform ...    37   0.024
gi|102467235 inner centromere protein antigens 135/155kDa isofor...    37   0.024
gi|102467242 inner centromere protein antigens 135/155kDa isofor...    37   0.024
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]        37   0.032
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi...    37   0.041
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]         37   0.041
gi|111955162 5-azacytidine induced 1 isoform b [Homo sapiens]          37   0.041
gi|111955084 5-azacytidine induced 1 isoform a [Homo sapiens]          37   0.041
gi|191252814 RIMS binding protein 3B [Homo sapiens]                    36   0.054
gi|191252806 RIMS binding protein 3C [Homo sapiens]                    36   0.054
gi|153792195 DKFZP434H0735 protein [Homo sapiens]                      36   0.054

>gi|7706712 sirtuin 7 [Homo sapiens]
          Length = 400

 Score =  808 bits (2086), Expect = 0.0
 Identities = 400/400 (100%), Positives = 400/400 (100%)

Query: 1   MAAGGLSRSERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTE 60
           MAAGGLSRSERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTE
Sbjct: 1   MAAGGLSRSERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTE 60

Query: 61  LQGRSRRREGLKRRQEEVCDDPEELRGKVRELASAVRNAKYLVVYTGAGISTAASIPDYR 120
           LQGRSRRREGLKRRQEEVCDDPEELRGKVRELASAVRNAKYLVVYTGAGISTAASIPDYR
Sbjct: 61  LQGRSRRREGLKRRQEEVCDDPEELRGKVRELASAVRNAKYLVVYTGAGISTAASIPDYR 120

Query: 121 GPNGVWTLLQKGRSVSAADLSEAEPTLTHMSITRLHEQKLVQHVVSQNCDGLHLRSGLPR 180
           GPNGVWTLLQKGRSVSAADLSEAEPTLTHMSITRLHEQKLVQHVVSQNCDGLHLRSGLPR
Sbjct: 121 GPNGVWTLLQKGRSVSAADLSEAEPTLTHMSITRLHEQKLVQHVVSQNCDGLHLRSGLPR 180

Query: 181 TAISELHGNMYIEVCTSCVPNREYVRVFDVTERTALHRHQTGRTCHKCGTQLRDTIVHFG 240
           TAISELHGNMYIEVCTSCVPNREYVRVFDVTERTALHRHQTGRTCHKCGTQLRDTIVHFG
Sbjct: 181 TAISELHGNMYIEVCTSCVPNREYVRVFDVTERTALHRHQTGRTCHKCGTQLRDTIVHFG 240

Query: 241 ERGTLGQPLNWEAATEAASRADTILCLGSSLKVLKKYPRLWCMTKPPSRRPKLYIVNLQW 300
           ERGTLGQPLNWEAATEAASRADTILCLGSSLKVLKKYPRLWCMTKPPSRRPKLYIVNLQW
Sbjct: 241 ERGTLGQPLNWEAATEAASRADTILCLGSSLKVLKKYPRLWCMTKPPSRRPKLYIVNLQW 300

Query: 301 TPKDDWAALKLHGKCDDVMRLLMAELGLEIPAYSRWQDPIFSLATPLRAGEEGSHSRKSL 360
           TPKDDWAALKLHGKCDDVMRLLMAELGLEIPAYSRWQDPIFSLATPLRAGEEGSHSRKSL
Sbjct: 301 TPKDDWAALKLHGKCDDVMRLLMAELGLEIPAYSRWQDPIFSLATPLRAGEEGSHSRKSL 360

Query: 361 CRSREEAPPGDRGAPLSSAPILGGWFGRGCTKRTKRKKVT 400
           CRSREEAPPGDRGAPLSSAPILGGWFGRGCTKRTKRKKVT
Sbjct: 361 CRSREEAPPGDRGAPLSSAPILGGWFGRGCTKRTKRKKVT 400


>gi|7706710 sirtuin 6 [Homo sapiens]
          Length = 355

 Score =  177 bits (448), Expect = 2e-44
 Identities = 120/281 (42%), Positives = 156/281 (55%), Gaps = 41/281 (14%)

Query: 77  EVCDDPEELRGKVRELASAVRNAKYLVVYTGAGISTAASIPDYRGPNGVWTLLQKGRSVS 136
           E+ D PEEL  KV ELA  V  +  +V +TGAGISTA+ IPD+RGP+GVWT+ ++G +  
Sbjct: 22  EIFDPPEELERKVWELARLVWQSSSVVFHTGAGISTASGIPDFRGPHGVWTMEERGLAPK 81

Query: 137 AADLSE-AEPTLTHMSITRLHEQKLVQHVVSQNCDGLHLRSGLPRTAISELHGNMYIEVC 195
                E A PT THM++ +L    L++ +VSQN DGLH+RSG PR  ++ELHGNM++E C
Sbjct: 82  FDTTFESARPTQTHMALVQLERVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEEC 141

Query: 196 TSCVPNREYVRVFDVTERTALHRHQTGRTC--------HKCGTQLRDTIVHFGERGTLGQ 247
             C    +YVR  D    T +    TGR C          C  +LRDTI           
Sbjct: 142 AKC--KTQYVR--DTVVGT-MGLKATGRLCTVAKARGLRACRGELRDTI----------- 185

Query: 248 PLNWE---------AATEAASRADTILCLGSSLKVLKKYPRLWCMTKPPSRRPKLYIVNL 298
            L+WE          A EA+  AD  + LG+SL++ +    L   TK   R  +L IVNL
Sbjct: 186 -LDWEDSLPDRDLALADEASRNADLSITLGTSLQI-RPSGNLPLATK--RRGGRLVIVNL 241

Query: 299 QWTPKDDWAALKLHGKCDDVMRLLMAELGLEIPAYSRWQDP 339
           Q T  D  A L++HG  D+VM  LM  LGLEIPA   W  P
Sbjct: 242 QPTKHDRHADLRIHGYVDEVMTRLMEHLGLEIPA---WDGP 279


>gi|6912662 sirtuin 4 [Homo sapiens]
          Length = 314

 Score = 86.3 bits (212), Expect = 5e-17
 Identities = 81/284 (28%), Positives = 129/284 (45%), Gaps = 54/284 (19%)

Query: 81  DPEELRGKVRELASAVRNAKYLVVYTGAGISTAASIPDYRGPN-GVWTL-----LQKGRS 134
           DPE    KV+EL   +  +K L+V TGAGIST + IPDYR    G++       +Q G  
Sbjct: 40  DPE----KVKELQRFITLSKRLLVMTGAGISTESGIPDYRSEKVGLYARTDRRPIQHGDF 95

Query: 135 VSAADL---------------SEAEPTLTHMSITRLHEQKLVQHVVSQNCDGLHLRSGLP 179
           V +A +               S  +P   H +++   +   +  +V+QN D LH ++G  
Sbjct: 96  VRSAPIRQRYWARNFVGWPQFSSHQPNPAHWALSTWEKLGKLYWLVTQNVDALHTKAGSR 155

Query: 180 RTAISELHGNMYIEVCTSCVPN------REYVRVFDVTERTALH---------------R 218
           R  ++ELHG M   +C  C         +E  +V + T     H               R
Sbjct: 156 R--LTELHGCMDRVLCLDCGEQTPRGVLQERFQVLNPTWSAEAHGLAPDGDVFLSEEQVR 213

Query: 219 HQTGRTCHKCGTQLRDTIVHFGERGTLGQPLNWEAATEAASRADTILCLGSSLKVLKKYP 278
                TC +CG  L+  +V FG+      P   +   +    AD++L +GSSL+V   Y 
Sbjct: 214 SFQVPTCVQCGGHLKPDVVFFGD---TVNPDKVDFVHKRVKEADSLLVVGSSLQVYSGY- 269

Query: 279 RLWCMTKPPSRRPKLYIVNLQWTPKDDWAALKLHGKCDDVMRLL 322
             + +T    + P + I+N+  T  DD A LKL+ +C +++ L+
Sbjct: 270 -RFILTAWEKKLP-IAILNIGPTRSDDLACLKLNSRCGELLPLI 311


>gi|6912660 sirtuin 3 isoform a [Homo sapiens]
          Length = 399

 Score = 66.2 bits (160), Expect = 5e-11
 Identities = 64/211 (30%), Positives = 93/211 (44%), Gaps = 40/211 (18%)

Query: 89  VRELASAVRNAKYLVVYTGAGISTAASIPDYRGP-NGVWTLLQ----------------- 130
           V EL  A R  + +VV  GAGIST + IPD+R P +G+++ LQ                 
Sbjct: 128 VAELIRA-RACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFF 186

Query: 131 ---KGRSVSAADL--SEAEPTLTHMSITRLHEQKLVQHVVSQNCDGLHLRSGLPRTAISE 185
              K     A +L     +P +TH  +  LH++ L+  + +QN DGL   SG+P + + E
Sbjct: 187 HNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVE 246

Query: 186 LHGNMYIEVCTSC---VPNREYVRVFDVTERTALHRHQTGRTCHKCGTQLRDTIVHFGER 242
            HG      CT C    P  E +R   + +R           C  C   ++  IV FGE 
Sbjct: 247 AHGTFASATCTVCQRPFPG-EDIRADVMADRVP--------RCPVCTGVVKPDIVFFGE- 296

Query: 243 GTLGQPLNWEAATEAASRADTILCLGSSLKV 273
                P  +         AD +L LG+SL+V
Sbjct: 297 ---PLPQRFLLHVVDFPMADLLLILGTSLEV 324


>gi|13775600 sirtuin 2 isoform 1 [Homo sapiens]
          Length = 389

 Score = 62.0 bits (149), Expect = 9e-10
 Identities = 65/252 (25%), Positives = 106/252 (42%), Gaps = 51/252 (20%)

Query: 75  QEEVCDDPEELRGKVRELASAVRNAKYLVVYTGAGISTAASIPDYRGPN-GVWTLLQKGR 133
           Q+E   D   L G  R + S     + ++   GAGIST+A IPD+R P+ G++  L+K  
Sbjct: 54  QKERLLDELTLEGVARYMQS--ERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYH 111

Query: 134 SVSAADLSEA----------------------EPTLTHMSITRLHEQKLVQHVVSQNCDG 171
                 + E                       +PT+ H  +  L ++ L+    +QN D 
Sbjct: 112 LPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDT 171

Query: 172 LHLRSGLPRTAISELHGNMYIEVCTSCVPNREY------VRVF-DVTERTALHRHQTGRT 224
           L   +GL +  + E HG  Y   C S     EY       ++F +VT +           
Sbjct: 172 LERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPK----------- 220

Query: 225 CHKCGTQLRDTIVHFGERGTLGQPLNWEAATEA-ASRADTILCLGSSLKVLKKYPRLWCM 283
           C  C + ++  IV FGE      P  + +  ++   + D +L +G+SL+V    P    +
Sbjct: 221 CEDCQSLVKPDIVFFGE----SLPARFFSCMQSDFLKVDLLLVMGTSLQV---QPFASLI 273

Query: 284 TKPPSRRPKLYI 295
           +K P   P+L I
Sbjct: 274 SKAPLSTPRLLI 285


>gi|13775602 sirtuin 2 isoform 2 [Homo sapiens]
          Length = 352

 Score = 62.0 bits (149), Expect = 9e-10
 Identities = 65/252 (25%), Positives = 106/252 (42%), Gaps = 51/252 (20%)

Query: 75  QEEVCDDPEELRGKVRELASAVRNAKYLVVYTGAGISTAASIPDYRGPN-GVWTLLQKGR 133
           Q+E   D   L G  R + S     + ++   GAGIST+A IPD+R P+ G++  L+K  
Sbjct: 17  QKERLLDELTLEGVARYMQS--ERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYH 74

Query: 134 SVSAADLSEA----------------------EPTLTHMSITRLHEQKLVQHVVSQNCDG 171
                 + E                       +PT+ H  +  L ++ L+    +QN D 
Sbjct: 75  LPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDT 134

Query: 172 LHLRSGLPRTAISELHGNMYIEVCTSCVPNREY------VRVF-DVTERTALHRHQTGRT 224
           L   +GL +  + E HG  Y   C S     EY       ++F +VT +           
Sbjct: 135 LERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPK----------- 183

Query: 225 CHKCGTQLRDTIVHFGERGTLGQPLNWEAATEA-ASRADTILCLGSSLKVLKKYPRLWCM 283
           C  C + ++  IV FGE      P  + +  ++   + D +L +G+SL+V    P    +
Sbjct: 184 CEDCQSLVKPDIVFFGE----SLPARFFSCMQSDFLKVDLLLVMGTSLQV---QPFASLI 236

Query: 284 TKPPSRRPKLYI 295
           +K P   P+L I
Sbjct: 237 SKAPLSTPRLLI 248


>gi|63054862 sirtuin 3 isoform b [Homo sapiens]
          Length = 257

 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 57/193 (29%), Positives = 84/193 (43%), Gaps = 39/193 (20%)

Query: 107 GAGISTAASIPDYRGP-NGVWTLLQ--------------------KGRSVSAADL--SEA 143
           GAGIST + IPD+R P +G+++ LQ                    K     A +L     
Sbjct: 3   GAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNY 62

Query: 144 EPTLTHMSITRLHEQKLVQHVVSQNCDGLHLRSGLPRTAISELHGNMYIEVCTSC---VP 200
           +P +TH  +  LH++ L+  + +QN DGL   SG+P + + E HG      CT C    P
Sbjct: 63  KPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFP 122

Query: 201 NREYVRVFDVTERTALHRHQTGRTCHKCGTQLRDTIVHFGERGTLGQPLNWEAATEAASR 260
             E +R   + +R           C  C   ++  IV FGE      P  +         
Sbjct: 123 G-EDIRADVMADRVP--------RCPVCTGVVKPDIVFFGE----PLPQRFLLHVVDFPM 169

Query: 261 ADTILCLGSSLKV 273
           AD +L LG+SL+V
Sbjct: 170 ADLLLILGTSLEV 182


>gi|6912664 sirtuin 5 isoform 1 [Homo sapiens]
          Length = 310

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 64/258 (24%), Positives = 97/258 (37%), Gaps = 55/258 (21%)

Query: 99  AKYLVVYTGAGISTAASIPDYRGPNGVWTLLQKGRSVSAADLS----------------- 141
           AK++V+ +GAG+S  + +P +RG  G W      R   A DL+                 
Sbjct: 50  AKHIVIISGAGVSAESGVPTFRGAGGYW------RKWQAQDLATPLAFAHNPSRVWEFYH 103

Query: 142 -------EAEPTLTHMSI----TRLHEQKLVQHVVSQNCDGLHLRSGLPRTAISELHGNM 190
                    EP   H +I    TRL +Q     V++QN D LH ++G     + E+HG++
Sbjct: 104 YRREVMGSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELHRKAGTKN--LLEIHGSL 161

Query: 191 YIEVCTSCVPNREYVRVFDVTERTALHRHQTGR-----------TCHK--CGTQLRDTIV 237
           +   CTSC    E  +       +     + G             C +  CG  LR  +V
Sbjct: 162 FKTRCTSCGVVAENYKSPICPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGGLLRPHVV 221

Query: 238 HFGERGTLGQPLNWEAATEAASRADTILCLGSSLKVLKKYPRLWCMTKPPSRRPKLYIVN 297
            FGE      P   E      +  D  L +G+S  V   YP      +  +R   +   N
Sbjct: 222 WFGEN---LDPAILEEVDRELAHCDLCLVVGTSSVV---YPAAMFAPQVAARGVPVAEFN 275

Query: 298 LQWTPKDDWAALKLHGKC 315
            + TP  +       G C
Sbjct: 276 TETTPATNRFRFHFQGPC 293


>gi|13787215 sirtuin 5 isoform 2 [Homo sapiens]
          Length = 299

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 62/245 (25%), Positives = 94/245 (38%), Gaps = 55/245 (22%)

Query: 99  AKYLVVYTGAGISTAASIPDYRGPNGVWTLLQKGRSVSAADLS----------------- 141
           AK++V+ +GAG+S  + +P +RG  G W      R   A DL+                 
Sbjct: 50  AKHIVIISGAGVSAESGVPTFRGAGGYW------RKWQAQDLATPLAFAHNPSRVWEFYH 103

Query: 142 -------EAEPTLTHMSI----TRLHEQKLVQHVVSQNCDGLHLRSGLPRTAISELHGNM 190
                    EP   H +I    TRL +Q     V++QN D LH ++G     + E+HG++
Sbjct: 104 YRREVMGSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELHRKAGTKN--LLEIHGSL 161

Query: 191 YIEVCTSCVPNREYVRVFDVTERTALHRHQTGR-----------TCHK--CGTQLRDTIV 237
           +   CTSC    E  +       +     + G             C +  CG  LR  +V
Sbjct: 162 FKTRCTSCGVVAENYKSPICPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGGLLRPHVV 221

Query: 238 HFGERGTLGQPLNWEAATEAASRADTILCLGSSLKVLKKYPRLWCMTKPPSRRPKLYIVN 297
            FGE      P   E      +  D  L +G+S  V   YP      +  +R   +   N
Sbjct: 222 WFGEN---LDPAILEEVDRELAHCDLCLVVGTSSVV---YPAAMFAPQVAARGVPVAEFN 275

Query: 298 LQWTP 302
            + TP
Sbjct: 276 TETTP 280


>gi|7657575 sirtuin 1 isoform a [Homo sapiens]
          Length = 747

 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 65/278 (23%), Positives = 111/278 (39%), Gaps = 61/278 (21%)

Query: 89  VRELASAVRNAKYLVVYTGAGISTAASIPDYRGPNGVWTLLQKGRSVSAADL-------- 140
           + +    ++  K ++V TGAG+S +  IPD+R  +G++  L    +V   DL        
Sbjct: 243 IEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARL----AVDFPDLPDPQAMFD 298

Query: 141 --------------------SEAEPTLTHMSITRLHEQKLVQHVVSQNCDGLHLRSGLPR 180
                                + +P+L H  I    ++  +    +QN D L   +G+ R
Sbjct: 299 IEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQR 358

Query: 181 TAISELHGNMYIEVCTSC--VPNREYVR--VFDVTERTALHRHQTGRTCHKCGTQ----- 231
             I + HG+     C  C    + E VR  +F          +Q    C +C        
Sbjct: 359 --IIQCHGSFATASCLICKYKVDCEAVRGDIF----------NQVVPRCPRCPADEPLAI 406

Query: 232 LRDTIVHFGERGTLGQPLNWEAATEAASRADTILCLGSSLKVLKKYPRLWCMTKPPSRRP 291
           ++  IV FGE   L +  +  A        D ++ +GSSLKV    P     +  P   P
Sbjct: 407 MKPEIVFFGE--NLPEQFH-RAMKYDKDEVDLLIVIGSSLKV---RPVALIPSSIPHEVP 460

Query: 292 KLYIVNLQWTPKDDWAALKLHGKCDDVMRLLMAELGLE 329
           ++ ++N +  P   +  ++L G CD ++  L   LG E
Sbjct: 461 QI-LINREPLPHLHF-DVELLGDCDVIINELCHRLGGE 496


>gi|239756174 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 625

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 34/99 (34%), Positives = 49/99 (49%), Gaps = 14/99 (14%)

Query: 4   GGLSRSERKAAERVRRL--REEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTEL 61
           G   R ER+AA R +R   R E++R  L +   +LR+  AER+A E RL       + + 
Sbjct: 419 GRRGREEREAARRRQRQYERSEERRRELAERQGLLRRERAERAAREDRLRK-----LQQE 473

Query: 62  QGRSRRREGLKRRQEEVCDDPEELRGKVRELASAVRNAK 100
           Q   +R EGL+  +E      E++R   RE A     AK
Sbjct: 474 QNLKQREEGLQEGRERA----EQIR---RERAQRAARAK 505


>gi|239750672 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 627

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 34/99 (34%), Positives = 49/99 (49%), Gaps = 14/99 (14%)

Query: 4   GGLSRSERKAAERVRRL--REEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTEL 61
           G   R ER+AA R +R   R E++R  L +   +LR+  AER+A E RL       + + 
Sbjct: 421 GRRGREEREAARRRQRQYERSEERRRELAERQGLLRRERAERAAREDRLRK-----LQQE 475

Query: 62  QGRSRRREGLKRRQEEVCDDPEELRGKVRELASAVRNAK 100
           Q   +R EGL+  +E      E++R   RE A     AK
Sbjct: 476 QNLKQREEGLQEGRERA----EQIR---RERAQRAARAK 507


>gi|239744982 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 627

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 34/99 (34%), Positives = 49/99 (49%), Gaps = 14/99 (14%)

Query: 4   GGLSRSERKAAERVRRL--REEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTEL 61
           G   R ER+AA R +R   R E++R  L +   +LR+  AER+A E RL       + + 
Sbjct: 421 GRRGREEREAARRRQRQYERSEERRRELAERQGLLRRERAERAAREDRLRK-----LQQE 475

Query: 62  QGRSRRREGLKRRQEEVCDDPEELRGKVRELASAVRNAK 100
           Q   +R EGL+  +E      E++R   RE A     AK
Sbjct: 476 QNLKQREEGLQEGRERA----EQIR---RERAQRAARAK 507


>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
           sapiens]
          Length = 570

 Score = 38.9 bits (89), Expect = 0.008
 Identities = 24/86 (27%), Positives = 48/86 (55%), Gaps = 6/86 (6%)

Query: 6   LSRSERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTELQGRS 65
           + R E K  E+ +++RE  Q E++R+   ++++   +   +EG++  + A +  E + + 
Sbjct: 434 MRRQEEKIREQEKKIRE--QEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKM-QEQEEKM 490

Query: 66  RRREGLKRRQEEVCDDPEELRGKVRE 91
           RR+E   R QE+   + EE   K+RE
Sbjct: 491 RRQEEKIREQEKKIREQEE---KIRE 513



 Score = 30.8 bits (68), Expect = 2.3
 Identities = 21/90 (23%), Positives = 46/90 (51%), Gaps = 8/90 (8%)

Query: 6   LSRSERKAAERVRRLREEQ----QRERLRQVSRILRKAAAERSAEEGRLLAESADLVTEL 61
           +   E++  +  +  R+E+    Q E++R+   ++++   E+  E+   + E  + + E 
Sbjct: 372 IREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQE-EKMGEQEEKMWEQEEEMQEQ 430

Query: 62  QGRSRRREGLKRRQEEVCDDPEELRGKVRE 91
           + + RR+E   R QE+   + EE   K+RE
Sbjct: 431 EEKMRRQEEKIREQEKKIREQEE---KIRE 457


>gi|148806928 hypothetical protein LOC57482 [Homo sapiens]
          Length = 1233

 Score = 38.9 bits (89), Expect = 0.008
 Identities = 33/97 (34%), Positives = 46/97 (47%), Gaps = 17/97 (17%)

Query: 1   MAAGGLSRSERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTE 60
           + A G   +ER+  E   RL  E++R RL+          A+  AEE R L E A L  E
Sbjct: 295 LEAPGWEDAERREREERERLEAEEERRRLQ----------AQAQAEERRRLEEDARL--E 342

Query: 61  LQGRSRRREG-----LKRRQEEVCDDPEELRGKVREL 92
            + R    EG     LKR++EE  +  EEL  +  E+
Sbjct: 343 ERRRQEEEEGRCAEELKRQEEEEAEGWEELEQQEAEV 379


>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
          Length = 793

 Score = 38.5 bits (88), Expect = 0.011
 Identities = 26/88 (29%), Positives = 46/88 (52%), Gaps = 6/88 (6%)

Query: 9   SERKAAERVRRLREEQQRERLRQVSRILRKAAAERS--AEEGRLLAESADLVTELQGR-S 65
           +E KAA + R  RE ++RER+R+     ++AA ER    EE +  AE    + E + R +
Sbjct: 297 AEEKAAAQERERREAEERERMREEE---KRAAEERQRIKEEEKRAAEERQRIKEEEKRAA 353

Query: 66  RRREGLKRRQEEVCDDPEELRGKVRELA 93
             R+ +K  ++   ++ +  R +  E A
Sbjct: 354 EERQRIKEEEKRAAEERQRARAEEEEKA 381



 Score = 34.3 bits (77), Expect = 0.20
 Identities = 29/94 (30%), Positives = 46/94 (48%), Gaps = 6/94 (6%)

Query: 3   AGGLSRSERKAAERVRRLREEQQR--ERLRQVSRILRKAAAERS--AEEGRLLAESADLV 58
           A    R  R+A ER  R+REE++R  E  +++    ++AA ER    EE +  AE    +
Sbjct: 301 AAAQERERREAEER-ERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRI 359

Query: 59  TELQGR-SRRREGLKRRQEEVCDDPEELRGKVRE 91
            E + R +  R+  +  +EE     E+ R K  E
Sbjct: 360 KEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLE 393



 Score = 30.0 bits (66), Expect = 3.9
 Identities = 27/112 (24%), Positives = 48/112 (42%), Gaps = 21/112 (18%)

Query: 10  ERKAAERVRRLREEQQRERLRQVSRIL---------RKAAA-----------ERSAEEGR 49
           ER  AER R   EE++R +  Q  +I           KAAA           ER  EE +
Sbjct: 263 ERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEK 322

Query: 50  LLAESADLVTELQGR-SRRREGLKRRQEEVCDDPEELRGKVRELASAVRNAK 100
             AE    + E + R +  R+ +K  ++   ++ + ++ + +  A   + A+
Sbjct: 323 RAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRAR 374



 Score = 28.9 bits (63), Expect = 8.6
 Identities = 14/33 (42%), Positives = 21/33 (63%)

Query: 11  RKAAERVRRLREEQQRERLRQVSRILRKAAAER 43
           RK  E  R+LREE+++ RL++     R  AAE+
Sbjct: 586 RKQEEADRKLREEEEKRRLKEEIERRRAEAAEK 618


>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
          Length = 749

 Score = 38.1 bits (87), Expect = 0.014
 Identities = 30/102 (29%), Positives = 50/102 (49%), Gaps = 10/102 (9%)

Query: 9   SERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEE---------GRLLAESA-DLV 58
           +E++   R +R +EE++R    ++ R  R+  A+R AEE          RL AE A +  
Sbjct: 484 AEKRRLAREQREKEERERREQEELERQKREELAQRVAEERTTRREEESRRLEAEQAREKE 543

Query: 59  TELQGRSRRREGLKRRQEEVCDDPEELRGKVRELASAVRNAK 100
            +LQ ++  R   +R + E     +E   +VRE A  VR  +
Sbjct: 544 EQLQRQAEERALREREEAERAQRQKEEEARVREEAERVRQER 585



 Score = 30.0 bits (66), Expect = 3.9
 Identities = 20/68 (29%), Positives = 34/68 (50%), Gaps = 2/68 (2%)

Query: 10  ERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTELQGRSRRRE 69
           ER+ AER +R +EE+ R R  +  R+ ++       EE   L E    + E+  R+RR E
Sbjct: 557 EREEAERAQRQKEEEARVR-EEAERVRQEREKHFQREEQERL-ERKKRLEEIMKRTRRTE 614

Query: 70  GLKRRQEE 77
              ++  +
Sbjct: 615 ATDKKTSD 622



 Score = 28.9 bits (63), Expect = 8.6
 Identities = 24/78 (30%), Positives = 34/78 (43%), Gaps = 14/78 (17%)

Query: 15  ERVRRLREEQQRERLRQVSRILRKAA---------AERSAEEGRLLAESADLVTE----- 60
           E  RRL  EQ RE+  Q+ R   + A         A+R  EE   + E A+ V +     
Sbjct: 529 EESRRLEAEQAREKEEQLQRQAEERALREREEAERAQRQKEEEARVREEAERVRQEREKH 588

Query: 61  LQGRSRRREGLKRRQEEV 78
            Q   + R   K+R EE+
Sbjct: 589 FQREEQERLERKKRLEEI 606


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 37.7 bits (86), Expect = 0.019
 Identities = 28/83 (33%), Positives = 45/83 (54%), Gaps = 3/83 (3%)

Query: 6   LSRSERKAAERVRRLREEQQRERLRQVSRILRKAAAER--SAEEGRLLAESADLVTELQG 63
           L + ER+   R R+  E+QQ +RLR+  ++ RK   ER    EE R   E  +   E + 
Sbjct: 278 LRKLERQELRRERQEEEQQQ-QRLRREQQLRRKQEEERREQQEERREQQERREQQEERRE 336

Query: 64  RSRRREGLKRRQEEVCDDPEELR 86
           +  RRE  +RR++++  + EE R
Sbjct: 337 QQLRREQEERREQQLRREQEEER 359



 Score = 36.6 bits (83), Expect = 0.041
 Identities = 26/80 (32%), Positives = 47/80 (58%), Gaps = 4/80 (5%)

Query: 15   ERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADL--VTELQGRSRRREGLK 72
            E  + LREE+++ RL++  R  R+   E   EE +LL E  +     EL+ + R+ E L+
Sbjct: 1029 EEEQLLREEREKRRLQERERQYRE-EEELQQEEEQLLGEERETRRRQELERQYRKEEELQ 1087

Query: 73   RRQEEVC-DDPEELRGKVRE 91
            + +E++  ++PE+ R + RE
Sbjct: 1088 QEEEQLLREEPEKRRRQERE 1107



 Score = 33.9 bits (76), Expect = 0.27
 Identities = 24/68 (35%), Positives = 36/68 (52%), Gaps = 4/68 (5%)

Query: 10  ERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTELQGRSRRRE 69
           E +  ER  +L EE++RE+  +  + LR+   ER   E RL  +  +    LQ R R  +
Sbjct: 481 EEERRERWLKLEEEERREQQERREQQLRREQEER--REQRLKRQEEE--ERLQQRLRSEQ 536

Query: 70  GLKRRQEE 77
            L+R QEE
Sbjct: 537 QLRREQEE 544



 Score = 33.9 bits (76), Expect = 0.27
 Identities = 25/89 (28%), Positives = 43/89 (48%), Gaps = 8/89 (8%)

Query: 6   LSRSERKAAERVRRLREE--------QQRERLRQVSRILRKAAAERSAEEGRLLAESADL 57
           L R E +  +R++R +EE        ++ ERL Q  R  ++   E   EE R     ++ 
Sbjct: 579 LKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEE 638

Query: 58  VTELQGRSRRREGLKRRQEEVCDDPEELR 86
             E + +  RRE  +RR++ +  + EE R
Sbjct: 639 QEERRQQQLRREQQERREQRLKREEEEER 667



 Score = 33.9 bits (76), Expect = 0.27
 Identities = 25/100 (25%), Positives = 49/100 (49%), Gaps = 8/100 (8%)

Query: 10   ERKAAERVRRLREEQQRER-----LRQVSRILRKAAAERSAEEGRLLAESADLVTELQGR 64
            +R+  ER R+ REE++ ++     LR+     R+   ER   E   + +  + +   +  
Sbjct: 1100 KRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPE 1159

Query: 65   SRRREGLKRR---QEEVCDDPEELRGKVRELASAVRNAKY 101
             RRR+ L+R+   +EE+  + E+L  + +E     R  +Y
Sbjct: 1160 KRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQY 1199



 Score = 33.1 bits (74), Expect = 0.46
 Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 11/88 (12%)

Query: 8    RSERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTELQGRSRR 67
            R +RK+ E  + LREE++ +R RQ           +  EE +LL E  +     Q R R+
Sbjct: 1309 RRDRKSQEEKQLLREEREEKRRRQ-------ETDRKFREEEQLLQEREEQPLRRQERDRK 1361

Query: 68   -REGLKRRQEE---VCDDPEELRGKVRE 91
             RE   R QE+     ++ + LR + RE
Sbjct: 1362 FREEELRHQEQGRKFLEEEQRLRRQERE 1389



 Score = 32.7 bits (73), Expect = 0.60
 Identities = 24/92 (26%), Positives = 46/92 (50%), Gaps = 8/92 (8%)

Query: 8    RSERKAAERVRRLREEQQRER-----LRQVSRILRKAAAERSAEEGRLLAESADLVTELQ 62
            R +R+  E+ R+ REE+Q ++     LR+     R+   ER   + + L +  + +   +
Sbjct: 918  REKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEE 977

Query: 63   GRSRRREGLK---RRQEEVCDDPEELRGKVRE 91
               RRR+  +   R +EE+  + E+L  + RE
Sbjct: 978  PEKRRRQEREKKYREEEELQQEEEQLLREERE 1009



 Score = 32.7 bits (73), Expect = 0.60
 Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 6/81 (7%)

Query: 11   RKAAERVRRLREEQQRER---LRQVSRILRKAAAERSAEEGRLLAESADLVTELQGRSRR 67
            R+  ER  R  EE Q+E    LR+     R+   ER   E   L +  + +   +   RR
Sbjct: 1073 RQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRR 1132

Query: 68   REGLKRR---QEEVCDDPEEL 85
            R+ L+R+   +EEV  + E+L
Sbjct: 1133 RQELERQYREEEEVQQEEEQL 1153



 Score = 32.3 bits (72), Expect = 0.78
 Identities = 20/62 (32%), Positives = 33/62 (53%), Gaps = 3/62 (4%)

Query: 16  RVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTELQGRSRRREGLKRRQ 75
           R +RL+ +++ ERL+Q  R  ++   E+     +LL    +   E   + RR + LKR Q
Sbjct: 515 REQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLE---QERREQRLKREQ 571

Query: 76  EE 77
           EE
Sbjct: 572 EE 573



 Score = 32.0 bits (71), Expect = 1.0
 Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 18/105 (17%)

Query: 5   GLSRSERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEG---RLLAESADLVTEL 61
           G    +++  ER  R+ +E++ +  R+   +LRK   +   EE    R L E  + + +L
Sbjct: 222 GREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKL 281

Query: 62  ---------------QGRSRRREGLKRRQEEVCDDPEELRGKVRE 91
                          Q R RR + L+R+QEE   + +E R + +E
Sbjct: 282 ERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQE 326



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 24/97 (24%), Positives = 47/97 (48%), Gaps = 12/97 (12%)

Query: 5    GLSRSERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTELQGR 64
            G    +R+  ER ++ REE++ ++  +  ++LR+   +R  +E        D + + + +
Sbjct: 975  GEEPEKRRRQEREKKYREEEELQQ--EEEQLLREEREKRRRQEWERQYRKKDELQQEEEQ 1032

Query: 65   SRRREGLKRR----------QEEVCDDPEELRGKVRE 91
              R E  KRR          +EE+  + E+L G+ RE
Sbjct: 1033 LLREEREKRRLQERERQYREEEELQQEEEQLLGEERE 1069



 Score = 31.2 bits (69), Expect = 1.7
 Identities = 20/73 (27%), Positives = 43/73 (58%), Gaps = 7/73 (9%)

Query: 10  ERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAE-----EGRLLAESADLVTELQGR 64
           E +  +R++R  EE++RE+  +++   ++ A ER        + +L +E+    +++  R
Sbjct: 665 EERLEQRLKREHEEERREQ--ELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSR 722

Query: 65  SRRREGLKRRQEE 77
            R++EG +RRQE+
Sbjct: 723 PRKQEGQRRRQEQ 735



 Score = 30.8 bits (68), Expect = 2.3
 Identities = 23/92 (25%), Positives = 45/92 (48%), Gaps = 8/92 (8%)

Query: 8    RSERKAAERVRRLREEQQRER-----LRQVSRILRKAAAERSAEEGRLLAESADLVTELQ 62
            R +R+  ER R+ REE++ ++     L +     R+   ER   +   L +  + +   +
Sbjct: 1038 REKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREE 1097

Query: 63   GRSRRREGLKRR---QEEVCDDPEELRGKVRE 91
               RRR+  +R+   +EE+  + E+L  + RE
Sbjct: 1098 PEKRRRQERERQCREEEELQQEEEQLLREERE 1129



 Score = 30.0 bits (66), Expect = 3.9
 Identities = 20/82 (24%), Positives = 41/82 (50%), Gaps = 1/82 (1%)

Query: 10   ERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTELQGRSRRRE 69
            +RK  E  ++LR +++  +  Q  + LR+   ER   E   L +  +   +L+ + R R+
Sbjct: 1690 DRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETE-QEQLRRQERYRK 1748

Query: 70   GLKRRQEEVCDDPEELRGKVRE 91
             L+  Q     + ++LR + R+
Sbjct: 1749 ILEEEQLRPEREEQQLRRQERD 1770



 Score = 29.6 bits (65), Expect = 5.0
 Identities = 22/87 (25%), Positives = 48/87 (55%), Gaps = 4/87 (4%)

Query: 8   RSERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTELQGRSRR 67
           RS+ +  ++  R + E++R+R R+ +   + A  E+  +E +LL E  + +   +   RR
Sbjct: 864 RSQEQRRDQKWRWQLEEERKR-RRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRR 922

Query: 68  REGLKRR---QEEVCDDPEELRGKVRE 91
           R+  +R+   +E++  + E+L  + RE
Sbjct: 923 RQEQERQYREEEQLQQEEEQLLREERE 949



 Score = 29.3 bits (64), Expect = 6.6
 Identities = 24/77 (31%), Positives = 40/77 (51%), Gaps = 7/77 (9%)

Query: 8   RSERKAAERVRRLREEQQRE-RLRQVSRILRKAAAERSAEEGR--LLAESADLVTELQGR 64
           + E +  +++RR +EE++RE +LR+  ++ R+    R  +  R   L     L  E Q R
Sbjct: 355 QEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 414

Query: 65  S----RRREGLKRRQEE 77
                RR + L+R QEE
Sbjct: 415 REQQLRREQQLRREQEE 431



 Score = 29.3 bits (64), Expect = 6.6
 Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 6/73 (8%)

Query: 10  ERKAAERVRRLREEQQ-RERLRQVSRILRKAAAERS-----AEEGRLLAESADLVTELQG 63
           E +  +R++R  EE++ ++RLR   ++ R+    R       EE RL  E  +   + + 
Sbjct: 512 EERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQ 571

Query: 64  RSRRREGLKRRQE 76
             RR + LKR +E
Sbjct: 572 EERRDQLLKREEE 584



 Score = 28.9 bits (63), Expect = 8.6
 Identities = 21/84 (25%), Positives = 37/84 (44%), Gaps = 2/84 (2%)

Query: 10  ERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAE--EGRLLAESADLVTELQGRSRR 67
           +R+  E  R+ +E Q+RE  R     L+      + E  +   L     L    +GR  +
Sbjct: 167 QRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEK 226

Query: 68  REGLKRRQEEVCDDPEELRGKVRE 91
           ++  + RQ+ V  + EE   + RE
Sbjct: 227 QQQRRERQDRVFQEEEEKEWRKRE 250



 Score = 28.9 bits (63), Expect = 8.6
 Identities = 20/79 (25%), Positives = 36/79 (45%), Gaps = 7/79 (8%)

Query: 6   LSRSERKAAERVRRLREEQQRERLRQVSRILRKAAAER-------SAEEGRLLAESADLV 58
           L R + +  + ++R  E ++ E+ R+  ++ R    ER         EE R   E  +  
Sbjct: 447 LKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQ 506

Query: 59  TELQGRSRRREGLKRRQEE 77
              +   RR + LKR++EE
Sbjct: 507 LRREQEERREQRLKRQEEE 525



 Score = 28.9 bits (63), Expect = 8.6
 Identities = 25/78 (32%), Positives = 39/78 (50%), Gaps = 7/78 (8%)

Query: 8    RSERKAAERVRRLREEQQRER-----LRQVSRILRKAAAERS-AEEGRLLAESADLVTEL 61
            R +R+  E  R+ REE++ ++     LR+     R+   ER   EE  L  E   L+ E 
Sbjct: 1128 REKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREE 1187

Query: 62   QGRSRR-REGLKRRQEEV 78
            Q + R+ RE   R +EE+
Sbjct: 1188 QEKRRQERERQYREEEEL 1205


>gi|62244004 modulator of estrogen induced transcription isoform b
           [Homo sapiens]
          Length = 1016

 Score = 37.4 bits (85), Expect = 0.024
 Identities = 25/86 (29%), Positives = 46/86 (53%), Gaps = 7/86 (8%)

Query: 6   LSRSERKAAERVRRLREEQQRERL-RQVSRI------LRKAAAERSAEEGRLLAESADLV 58
           ++  ER+  ER+R +RE ++RERL R+  R+      L +   ER   E   +    +  
Sbjct: 619 IAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERR 678

Query: 59  TELQGRSRRREGLKRRQEEVCDDPEE 84
            E +  +R RE L+R+Q+++  + E+
Sbjct: 679 KEAERIAREREELRRQQQQLRYEQEK 704


>gi|63176611 modulator of estrogen induced transcription isoform a
           [Homo sapiens]
          Length = 1034

 Score = 37.4 bits (85), Expect = 0.024
 Identities = 25/86 (29%), Positives = 46/86 (53%), Gaps = 7/86 (8%)

Query: 6   LSRSERKAAERVRRLREEQQRERL-RQVSRI------LRKAAAERSAEEGRLLAESADLV 58
           ++  ER+  ER+R +RE ++RERL R+  R+      L +   ER   E   +    +  
Sbjct: 637 IAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERR 696

Query: 59  TELQGRSRRREGLKRRQEEVCDDPEE 84
            E +  +R RE L+R+Q+++  + E+
Sbjct: 697 KEAERIAREREELRRQQQQLRYEQEK 722


>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
           [Homo sapiens]
          Length = 918

 Score = 37.4 bits (85), Expect = 0.024
 Identities = 30/98 (30%), Positives = 50/98 (51%), Gaps = 12/98 (12%)

Query: 6   LSRSER-----KAAERVRRLREEQQR---ERLRQVSRILRKAAAERSAEEGRLLAESADL 57
           L R ER     +A ERV +++EE+++   ++  Q+     KA  ER AEE      +A  
Sbjct: 572 LKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKK 631

Query: 58  VTELQGRSRRREGLKR----RQEEVCDDPEELRGKVRE 91
           + E++ R ++ E  +R    +QEE     +EL  K +E
Sbjct: 632 MEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKE 669



 Score = 36.2 bits (82), Expect = 0.054
 Identities = 31/94 (32%), Positives = 40/94 (42%), Gaps = 12/94 (12%)

Query: 9   SERKAAERVRRLREEQQRERLRQVSRILRKAAAE-----RSAEEGRLLAESADLVTELQG 63
           + RK  E  RRLR  QQ E  R+   +L+K   E     R A E + LAE  +     Q 
Sbjct: 637 ARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQE 696

Query: 64  R-------SRRREGLKRRQEEVCDDPEELRGKVR 90
           R         RRE  +R QE    + E  R + R
Sbjct: 697 RREQERREQERREQERREQERQLAEQERRREQER 730



 Score = 34.3 bits (77), Expect = 0.20
 Identities = 30/89 (33%), Positives = 46/89 (51%), Gaps = 12/89 (13%)

Query: 8   RSERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTELQGRSR- 66
           R E++  E+ RR +E +++ER  Q  ++   A  ER  E+ RL AE      ELQ R + 
Sbjct: 692 RREQERREQERREQERREQERREQERQL---AEQERRREQERLQAE-----RELQEREKA 743

Query: 67  ---RREGLKRRQEEVCDDPEELRGKVREL 92
              ++E L+R  EE     E+ R   R+L
Sbjct: 744 LRLQKEQLQRELEEKKKKEEQQRLAERQL 772


>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
           [Homo sapiens]
          Length = 914

 Score = 37.4 bits (85), Expect = 0.024
 Identities = 30/98 (30%), Positives = 50/98 (51%), Gaps = 12/98 (12%)

Query: 6   LSRSER-----KAAERVRRLREEQQR---ERLRQVSRILRKAAAERSAEEGRLLAESADL 57
           L R ER     +A ERV +++EE+++   ++  Q+     KA  ER AEE      +A  
Sbjct: 568 LKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKK 627

Query: 58  VTELQGRSRRREGLKR----RQEEVCDDPEELRGKVRE 91
           + E++ R ++ E  +R    +QEE     +EL  K +E
Sbjct: 628 MEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKE 665



 Score = 36.2 bits (82), Expect = 0.054
 Identities = 31/94 (32%), Positives = 40/94 (42%), Gaps = 12/94 (12%)

Query: 9   SERKAAERVRRLREEQQRERLRQVSRILRKAAAE-----RSAEEGRLLAESADLVTELQG 63
           + RK  E  RRLR  QQ E  R+   +L+K   E     R A E + LAE  +     Q 
Sbjct: 633 ARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQE 692

Query: 64  R-------SRRREGLKRRQEEVCDDPEELRGKVR 90
           R         RRE  +R QE    + E  R + R
Sbjct: 693 RREQERREQERREQERREQERQLAEQERRREQER 726



 Score = 34.3 bits (77), Expect = 0.20
 Identities = 30/89 (33%), Positives = 46/89 (51%), Gaps = 12/89 (13%)

Query: 8   RSERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTELQGRSR- 66
           R E++  E+ RR +E +++ER  Q  ++   A  ER  E+ RL AE      ELQ R + 
Sbjct: 688 RREQERREQERREQERREQERREQERQL---AEQERRREQERLQAE-----RELQEREKA 739

Query: 67  ---RREGLKRRQEEVCDDPEELRGKVREL 92
              ++E L+R  EE     E+ R   R+L
Sbjct: 740 LRLQKEQLQRELEEKKKKEEQQRLAERQL 768


>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
          Length = 1564

 Score = 37.0 bits (84), Expect = 0.032
 Identities = 32/89 (35%), Positives = 43/89 (48%), Gaps = 5/89 (5%)

Query: 6   LSRSERKAAERVRRL---REEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTELQ 62
           L R ER+   RV R+   R+E+ RER R+  R  R+   ER  E  R   +  +L  E +
Sbjct: 654 LERDERREERRVDRVDDRRDERARERDRERERD-RERERERERERDREREKERELERE-R 711

Query: 63  GRSRRREGLKRRQEEVCDDPEELRGKVRE 91
            R R RE  K R  E   D +  R + RE
Sbjct: 712 AREREREREKERDRERDRDRDHDRERERE 740



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 24/73 (32%), Positives = 37/73 (50%), Gaps = 5/73 (6%)

Query: 10  ERKAAERVRRLREEQQRERLRQVSRIL-RKAAAERSAEEGRLLAESADLVTELQGRSRRR 68
           ER   +   R REE++RER R+  R   R+   ER+ E  +      D   + +GR  RR
Sbjct: 742 ERDREKEREREREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRR 801

Query: 69  EGLKRRQEEVCDD 81
           E    ++EE+ +D
Sbjct: 802 E----KREEIRED 810


>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 123

 Score = 36.6 bits (83), Expect = 0.041
 Identities = 21/84 (25%), Positives = 45/84 (53%), Gaps = 1/84 (1%)

Query: 8   RSERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTELQGRSRR 67
           + ++K  +   + +E+++ E+ R+  R  +K   ER  EE     E  +   E +GR R+
Sbjct: 40  KEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKE-EGRRRK 98

Query: 68  REGLKRRQEEVCDDPEELRGKVRE 91
           ++  +RR+EE  +  ++ R K ++
Sbjct: 99  KKKKRRRKEEEEEKKKKRRRKTKK 122


>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
          Length = 1317

 Score = 36.6 bits (83), Expect = 0.041
 Identities = 27/92 (29%), Positives = 47/92 (51%), Gaps = 6/92 (6%)

Query: 11   RKAAERVRRLREEQQRERL-RQVSRILRK-AAAERSAEEGRLLAESADLVTELQGRSRRR 68
            RK  + +   RE+QQRE L R ++R+ R+ +A +R +  G  + E    +  L   SR +
Sbjct: 987  RKKEKEILESREKQQREALERALARLERRHSALQRHSTLGMEIEEQRQKLASLNSGSREQ 1046

Query: 69   EG----LKRRQEEVCDDPEELRGKVRELASAV 96
             G    L+  QE +  D E L  ++++L   +
Sbjct: 1047 SGLQASLEAEQEALEKDQERLEYEIQQLKQKI 1078


>gi|111955162 5-azacytidine induced 1 isoform b [Homo sapiens]
          Length = 1044

 Score = 36.6 bits (83), Expect = 0.041
 Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 17/95 (17%)

Query: 9   SERKAAERVRRLREEQQRE--RLRQVSRILRKAAAERSAEEGRLLAESADLVTELQGRSR 66
           SE+ A  R++RLR++ + E   L Q  R L++  +E   + G           E +G + 
Sbjct: 879 SEKAAESRIKRLRDKYEAELSELEQSERKLQERCSELKGQLG-----------EAEGENL 927

Query: 67  RREGLKRRQEEVCDDP----EELRGKVRELASAVR 97
           R +GL R++E   +D     E+L  +   LA  +R
Sbjct: 928 RLQGLVRQKERALEDAQAVNEQLSSERSNLAQVIR 962



 Score = 32.3 bits (72), Expect = 0.78
 Identities = 24/85 (28%), Positives = 41/85 (48%), Gaps = 9/85 (10%)

Query: 15  ERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTELQGRSRRREGLKRR 74
           + VRRL+   + E L+   R     A++R   +   L E  +   E  G+  R    +R+
Sbjct: 721 QEVRRLKSLHEAELLQSDER-----ASQRCLRQAEELREQLEREKEALGQQERERARQRQ 775

Query: 75  QEEVCDDPEELRGKVRELASAVRNA 99
           + E+    EELR ++ E +SA+  A
Sbjct: 776 RAEL----EELRQQLEESSSALTRA 796


>gi|111955084 5-azacytidine induced 1 isoform a [Homo sapiens]
          Length = 1080

 Score = 36.6 bits (83), Expect = 0.041
 Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 17/95 (17%)

Query: 9   SERKAAERVRRLREEQQRE--RLRQVSRILRKAAAERSAEEGRLLAESADLVTELQGRSR 66
           SE+ A  R++RLR++ + E   L Q  R L++  +E   + G           E +G + 
Sbjct: 915 SEKAAESRIKRLRDKYEAELSELEQSERKLQERCSELKGQLG-----------EAEGENL 963

Query: 67  RREGLKRRQEEVCDDP----EELRGKVRELASAVR 97
           R +GL R++E   +D     E+L  +   LA  +R
Sbjct: 964 RLQGLVRQKERALEDAQAVNEQLSSERSNLAQVIR 998


>gi|191252814 RIMS binding protein 3B [Homo sapiens]
          Length = 1639

 Score = 36.2 bits (82), Expect = 0.054
 Identities = 31/104 (29%), Positives = 49/104 (47%), Gaps = 3/104 (2%)

Query: 5   GLSRSERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAE-SADLVTELQG 63
           G     R+ A R R+LREE +RER +   R+  K  A+RS E  +L  E   +   E++ 
Sbjct: 46  GWRAERRRFAARERQLREEAERERRQLADRLRSKWEAQRSRELRQLQEEMQREREAEIRQ 105

Query: 64  RSRRREGLKRRQEEVCDDPEELRGKVRELASAVRNAKYLVVYTG 107
             R +E  +R+ +++     E  G VR+     R     +V  G
Sbjct: 106 LLRWKEAEQRQLQQLLH--RERDGVVRQARELQRQLAEELVNRG 147


>gi|191252806 RIMS binding protein 3C [Homo sapiens]
          Length = 1639

 Score = 36.2 bits (82), Expect = 0.054
 Identities = 31/104 (29%), Positives = 49/104 (47%), Gaps = 3/104 (2%)

Query: 5   GLSRSERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAE-SADLVTELQG 63
           G     R+ A R R+LREE +RER +   R+  K  A+RS E  +L  E   +   E++ 
Sbjct: 46  GWRAERRRFAARERQLREEAERERRQLADRLRSKWEAQRSRELRQLQEEMQREREAEIRQ 105

Query: 64  RSRRREGLKRRQEEVCDDPEELRGKVRELASAVRNAKYLVVYTG 107
             R +E  +R+ +++     E  G VR+     R     +V  G
Sbjct: 106 LLRWKEAEQRQLQQLLH--RERDGVVRQARELQRQLAEELVNRG 147


>gi|153792195 DKFZP434H0735 protein [Homo sapiens]
          Length = 1639

 Score = 36.2 bits (82), Expect = 0.054
 Identities = 31/104 (29%), Positives = 49/104 (47%), Gaps = 3/104 (2%)

Query: 5   GLSRSERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAE-SADLVTELQG 63
           G     R+ A R R+LREE +RER +   R+  K  A+RS E  +L  E   +   E++ 
Sbjct: 46  GWRAERRRFAARERQLREEAERERRQLADRLRSKWEAQRSRELRQLQEEMQREREAEIRQ 105

Query: 64  RSRRREGLKRRQEEVCDDPEELRGKVRELASAVRNAKYLVVYTG 107
             R +E  +R+ +++     E  G VR+     R     +V  G
Sbjct: 106 LLRWKEAEQRQLQQLLH--RERDGVVRQARELQRQLAEELVNRG 147


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,763,329
Number of Sequences: 37866
Number of extensions: 730163
Number of successful extensions: 4283
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 102
Number of HSP's successfully gapped in prelim test: 139
Number of HSP's that attempted gapping in prelim test: 3447
Number of HSP's gapped (non-prelim): 792
length of query: 400
length of database: 18,247,518
effective HSP length: 104
effective length of query: 296
effective length of database: 14,309,454
effective search space: 4235598384
effective search space used: 4235598384
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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