Guide to the Human Genome
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Search of human proteins with 7706186

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7706186 tumor necrosis factor receptor superfamily, member
12A [Homo sapiens]
         (129 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7706186 tumor necrosis factor receptor superfamily, member 12...   270   3e-73
gi|112420992 crumbs homolog 2 [Homo sapiens]                           35   0.013
gi|16445027 BAFF receptor [Homo sapiens]                               34   0.028
gi|14861860 testicular acid phosphatase precursor [Homo sapiens]       33   0.081
gi|33383239 protein kinase Myt1 isoform 2 [Homo sapiens]               28   1.5  
gi|23200021 tumor necrosis factor receptor superfamily, member 2...    28   2.0  
gi|110225353 sprouty-related, EVH1 domain containing 3 isoform a...    28   2.0  
gi|145309315 G protein-coupled receptor 62 [Homo sapiens]              28   2.0  
gi|71274180 PLAC8-like 1 [Homo sapiens]                                28   2.6  
gi|190343004 EGF-containing fibulin-like extracellular matrix pr...    27   3.4  
gi|50659100 regeneration associated muscle protease isoform b [H...    27   3.4  
gi|50659098 regeneration associated muscle protease isoform a [H...    27   3.4  
gi|86788132 EGF-containing fibulin-like extracellular matrix pro...    27   3.4  
gi|86788015 EGF-containing fibulin-like extracellular matrix pro...    27   3.4  
gi|9665262 EGF-containing fibulin-like extracellular matrix prot...    27   3.4  
gi|149393138 hypothetical protein LOC84067 isoform 2 [Homo sapiens]    27   4.5  
gi|149393140 hypothetical protein LOC84067 isoform 1 [Homo sapiens]    27   4.5  
gi|30795117 F-box only protein, helicase, 18 isoform 1 [Homo sap...    27   4.5  
gi|30795119 F-box only protein, helicase, 18 isoform 2 [Homo sap...    27   4.5  
gi|22749289 hypothetical protein LOC170062 [Homo sapiens]              27   4.5  
gi|148727335 patatin-like phospholipase domain containing 7 isof...    27   5.8  
gi|88758613 CD93 antigen precursor [Homo sapiens]                      27   5.8  
gi|14589891 cadherin 3, type 1 preproprotein [Homo sapiens]            27   5.8  
gi|71043500 beta 1,4-N-acetylgalactosaminyltransferase-transfera...    26   7.6  
gi|93204881 Rab interacting lysosomal protein [Homo sapiens]           26   7.6  
gi|110347437 latent transforming growth factor beta binding prot...    26   7.6  
gi|110347412 latent transforming growth factor beta binding prot...    26   7.6  
gi|110347431 latent transforming growth factor beta binding prot...    26   7.6  
gi|21281681 leucine-rich repeat LGI family, member 3 [Homo sapiens]    26   7.6  
gi|167614500 lymphocyte-activation protein 3 precursor [Homo sap...    26   7.6  

>gi|7706186 tumor necrosis factor receptor superfamily, member 12A
           [Homo sapiens]
          Length = 129

 Score =  270 bits (689), Expect = 3e-73
 Identities = 129/129 (100%), Positives = 129/129 (100%)

Query: 1   MARGSLRRLLRLLVLGLWLALLRSVAGEQAPGTAPCSRGSSWSADLDKCMDCASCRARPH 60
           MARGSLRRLLRLLVLGLWLALLRSVAGEQAPGTAPCSRGSSWSADLDKCMDCASCRARPH
Sbjct: 1   MARGSLRRLLRLLVLGLWLALLRSVAGEQAPGTAPCSRGSSWSADLDKCMDCASCRARPH 60

Query: 61  SDFCLGCAAAPPAPFRLLWPILGGALSLTFVLGLLSGFLVWRRCRRREKFTTPIEETGGE 120
           SDFCLGCAAAPPAPFRLLWPILGGALSLTFVLGLLSGFLVWRRCRRREKFTTPIEETGGE
Sbjct: 61  SDFCLGCAAAPPAPFRLLWPILGGALSLTFVLGLLSGFLVWRRCRRREKFTTPIEETGGE 120

Query: 121 GCPAVALIQ 129
           GCPAVALIQ
Sbjct: 121 GCPAVALIQ 129


>gi|112420992 crumbs homolog 2 [Homo sapiens]
          Length = 1285

 Score = 35.4 bits (80), Expect = 0.013
 Identities = 29/87 (33%), Positives = 41/87 (47%), Gaps = 9/87 (10%)

Query: 35   PCSRGSSWSA--DLDKCMDCASCRARPHSDFCLGCAAAP-PAPFRLLWPILGGALS--LT 89
            PC  G +  A   + +C+    C AR    FC      P P PF LL   +  A +  L 
Sbjct: 1181 PCLNGGTCRAAGGVSECI----CNARFSGQFCEVAKGLPLPLPFPLLEVAVPAACACLLL 1236

Query: 90   FVLGLLSGFLVWRRCRRREKFTTPIEE 116
             +LGLLSG L  R+ R+ E   +P ++
Sbjct: 1237 LLLGLLSGILAARKRRQSEGTYSPSQQ 1263


>gi|16445027 BAFF receptor [Homo sapiens]
          Length = 184

 Score = 34.3 bits (77), Expect = 0.028
 Identities = 35/120 (29%), Positives = 46/120 (38%), Gaps = 27/120 (22%)

Query: 23  RSVAGEQAPGTAPCSRGSSWSADLDKCMDCASCRA-RPHSDFCLGCAAAPPAPFRLLWP- 80
           RS+ G  AP   PC     +   +  C+ C   R  RP         A+ PAP   L P 
Sbjct: 6   RSLRGRDAPAPTPCVPAECFDLLVRHCVACGLLRTPRPKP-----AGASSPAPRTALQPQ 60

Query: 81  ----------------ILGGA---LSLTFVLGL-LSGFLVWRRCRRREKFTTPIEETGGE 120
                           +L GA   L L  VL L L G + WRR +RR +  +  E   G+
Sbjct: 61  ESVGAGAGEAALPLPGLLFGAPALLGLALVLALVLVGLVSWRRRQRRLRGASSAEAPDGD 120


>gi|14861860 testicular acid phosphatase precursor [Homo sapiens]
          Length = 426

 Score = 32.7 bits (73), Expect = 0.081
 Identities = 25/71 (35%), Positives = 31/71 (43%), Gaps = 12/71 (16%)

Query: 34  APCSRGSSWSADLDKCMDCASCRARPHSDFCLGC--AAAPPAPFRLLWPILGGALSLTFV 91
           APC  G  +          A  R   H   C G   AA PPAP   + P+L GA+++   
Sbjct: 355 APCPLGRFYQLT-------APARPPAHGVSCHGPYEAAIPPAP---VVPLLAGAVAVLVA 404

Query: 92  LGLLSGFLVWR 102
           L L  G L WR
Sbjct: 405 LSLGLGLLAWR 415


>gi|33383239 protein kinase Myt1 isoform 2 [Homo sapiens]
          Length = 480

 Score = 28.5 bits (62), Expect = 1.5
 Identities = 32/103 (31%), Positives = 40/103 (38%), Gaps = 31/103 (30%)

Query: 1   MARG-SLRRLLRLLVLGLWLALLRSVAGEQA-------PGTAPCSR------GSSWSADL 46
           ++RG +L + L  L+  LW  L    +  Q        PG+ PCS        S+W  D 
Sbjct: 376 LSRGWALWQALLALLCWLWHGLAHPASWLQPLGPPATPPGSPPCSLLLDSSLSSNWDDD- 434

Query: 47  DKCMDCASCRARPHSDFCLGCAAAPPA----PFRLLWPILGGA 85
                       P    CL C   PPA    P RL WP L GA
Sbjct: 435 ---------SLGPGHPPCLAC---PPAGLHSPLRLSWPGLWGA 465


>gi|23200021 tumor necrosis factor receptor superfamily, member 25
           isoform 1 precursor [Homo sapiens]
          Length = 426

 Score = 28.1 bits (61), Expect = 2.0
 Identities = 17/61 (27%), Positives = 26/61 (42%), Gaps = 11/61 (18%)

Query: 51  DCASCRAR--PHSDFCLGCAAAPPAPFRLLW---------PILGGALSLTFVLGLLSGFL 99
           DC +C      H D C+ C   PP+     W          + GG + + +V  LL+G +
Sbjct: 161 DCGTCLPGFYEHGDGCVSCPTPPPSLAGAPWGAVQSAVPLSVAGGRVGVFWVQVLLAGLV 220

Query: 100 V 100
           V
Sbjct: 221 V 221


>gi|110225353 sprouty-related, EVH1 domain containing 3 isoform a
           [Homo sapiens]
          Length = 410

 Score = 28.1 bits (61), Expect = 2.0
 Identities = 18/50 (36%), Positives = 23/50 (46%), Gaps = 2/50 (4%)

Query: 31  PGTAPCSRGSSWSADLDKCMDCASCRA--RPHSDFCLGCAAAPPAPFRLL 78
           PG  P S  +  S + ++   C  CRA  R  +D   G  A  P P RLL
Sbjct: 276 PGPGPSSAPAKASPEAEEAARCVHCRALFRRRADGRGGRCAEAPDPGRLL 325


>gi|145309315 G protein-coupled receptor 62 [Homo sapiens]
          Length = 368

 Score = 28.1 bits (61), Expect = 2.0
 Identities = 21/57 (36%), Positives = 24/57 (42%), Gaps = 14/57 (24%)

Query: 65  LGCAAAPP-------------APFRLLWPILGGALSLTFVLGLLSG-FLVWRRCRRR 107
           LG   APP              PFR LW +L  AL    +LG   G F+V RR   R
Sbjct: 149 LGTPPAPPPAPARCSVLAGGLGPFRPLWALLAFALPALLLLGAYGGIFVVARRAALR 205


>gi|71274180 PLAC8-like 1 [Homo sapiens]
          Length = 177

 Score = 27.7 bits (60), Expect = 2.6
 Identities = 21/61 (34%), Positives = 23/61 (37%), Gaps = 4/61 (6%)

Query: 33  TAPCSRGSSWSADL-DKCMDCASCRARPHSDFCLGCAAAPPAPFRLLWPILGGALSLTFV 91
           TA    G  WS  L   C D   C        CL C  A      L WP+L G+   TF 
Sbjct: 63  TAIVQTGGGWSTGLFSVCRDRRICFCGLFCPMCLECDIARHYGECLCWPLLPGS---TFA 119

Query: 92  L 92
           L
Sbjct: 120 L 120


>gi|190343004 EGF-containing fibulin-like extracellular matrix
          protein 2 [Homo sapiens]
          Length = 443

 Score = 27.3 bits (59), Expect = 3.4
 Identities = 16/53 (30%), Positives = 21/53 (39%), Gaps = 3/53 (5%)

Query: 12 LLVLGLWLALLRSVA---GEQAPGTAPCSRGSSWSADLDKCMDCASCRARPHS 61
          LL+  L L LL S +    E+      C+ G  W  D   C D   C   P +
Sbjct: 12 LLLWALLLLLLGSASPQDSEEPDSYTECTDGYEWDPDSQHCRDVNECLTIPEA 64


>gi|50659100 regeneration associated muscle protease isoform b [Homo
           sapiens]
          Length = 720

 Score = 27.3 bits (59), Expect = 3.4
 Identities = 15/41 (36%), Positives = 17/41 (41%), Gaps = 4/41 (9%)

Query: 38  RGSSWSADLD----KCMDCASCRARPHSDFCLGCAAAPPAP 74
           R  SW   LD    K   CA CRA  +   C+ C     AP
Sbjct: 95  RNGSWGGTLDDFYVKGFYCAECRAGWYGGDCMRCGQVLRAP 135


>gi|50659098 regeneration associated muscle protease isoform a [Homo
           sapiens]
          Length = 737

 Score = 27.3 bits (59), Expect = 3.4
 Identities = 15/41 (36%), Positives = 17/41 (41%), Gaps = 4/41 (9%)

Query: 38  RGSSWSADLD----KCMDCASCRARPHSDFCLGCAAAPPAP 74
           R  SW   LD    K   CA CRA  +   C+ C     AP
Sbjct: 95  RNGSWGGTLDDFYVKGFYCAECRAGWYGGDCMRCGQVLRAP 135


>gi|86788132 EGF-containing fibulin-like extracellular matrix
          protein 1 precursor [Homo sapiens]
          Length = 493

 Score = 27.3 bits (59), Expect = 3.4
 Identities = 18/58 (31%), Positives = 24/58 (41%), Gaps = 2/58 (3%)

Query: 9  LLRLLVLGLWLALLRSVAGEQAPGTAPCSRGSSWSADLDKCMDCASCRARPHSDFCLG 66
          L  L +  L LAL++S   E+      C+ G  W     +C D   C   P  D C G
Sbjct: 2  LKALFLTMLTLALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDECDIVP--DACKG 57


>gi|86788015 EGF-containing fibulin-like extracellular matrix
          protein 1 precursor [Homo sapiens]
          Length = 493

 Score = 27.3 bits (59), Expect = 3.4
 Identities = 18/58 (31%), Positives = 24/58 (41%), Gaps = 2/58 (3%)

Query: 9  LLRLLVLGLWLALLRSVAGEQAPGTAPCSRGSSWSADLDKCMDCASCRARPHSDFCLG 66
          L  L +  L LAL++S   E+      C+ G  W     +C D   C   P  D C G
Sbjct: 2  LKALFLTMLTLALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDECDIVP--DACKG 57


>gi|9665262 EGF-containing fibulin-like extracellular matrix
          protein 1 precursor [Homo sapiens]
          Length = 493

 Score = 27.3 bits (59), Expect = 3.4
 Identities = 18/58 (31%), Positives = 24/58 (41%), Gaps = 2/58 (3%)

Query: 9  LLRLLVLGLWLALLRSVAGEQAPGTAPCSRGSSWSADLDKCMDCASCRARPHSDFCLG 66
          L  L +  L LAL++S   E+      C+ G  W     +C D   C   P  D C G
Sbjct: 2  LKALFLTMLTLALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDECDIVP--DACKG 57


>gi|149393138 hypothetical protein LOC84067 isoform 2 [Homo sapiens]
          Length = 972

 Score = 26.9 bits (58), Expect = 4.5
 Identities = 11/21 (52%), Positives = 15/21 (71%)

Query: 23  RSVAGEQAPGTAPCSRGSSWS 43
           +S+ G ++PG APCS G S S
Sbjct: 509 QSLGGSESPGPAPCSPGLSAS 529


>gi|149393140 hypothetical protein LOC84067 isoform 1 [Homo sapiens]
          Length = 986

 Score = 26.9 bits (58), Expect = 4.5
 Identities = 11/21 (52%), Positives = 15/21 (71%)

Query: 23  RSVAGEQAPGTAPCSRGSSWS 43
           +S+ G ++PG APCS G S S
Sbjct: 523 QSLGGSESPGPAPCSPGLSAS 543


>gi|30795117 F-box only protein, helicase, 18 isoform 1 [Homo
           sapiens]
          Length = 1094

 Score = 26.9 bits (58), Expect = 4.5
 Identities = 11/20 (55%), Positives = 15/20 (75%)

Query: 26  AGEQAPGTAPCSRGSSWSAD 45
           AG  +PG+AP SR  SWS++
Sbjct: 160 AGPGSPGSAPPSRKRSWSSE 179


>gi|30795119 F-box only protein, helicase, 18 isoform 2 [Homo
           sapiens]
          Length = 1043

 Score = 26.9 bits (58), Expect = 4.5
 Identities = 11/20 (55%), Positives = 15/20 (75%)

Query: 26  AGEQAPGTAPCSRGSSWSAD 45
           AG  +PG+AP SR  SWS++
Sbjct: 109 AGPGSPGSAPPSRKRSWSSE 128


>gi|22749289 hypothetical protein LOC170062 [Homo sapiens]
          Length = 645

 Score = 26.9 bits (58), Expect = 4.5
 Identities = 13/27 (48%), Positives = 14/27 (51%), Gaps = 4/27 (14%)

Query: 101 WRRCRRREKFTTPIEETG----GEGCP 123
           W RC  REK T    E+G    GE CP
Sbjct: 163 WARCEAREKTTEVPTESGKYPCGESCP 189


>gi|148727335 patatin-like phospholipase domain containing 7 isoform
           a [Homo sapiens]
          Length = 1342

 Score = 26.6 bits (57), Expect = 5.8
 Identities = 20/63 (31%), Positives = 29/63 (46%), Gaps = 8/63 (12%)

Query: 59  PHSDFCLGCA--------AAPPAPFRLLWPILGGALSLTFVLGLLSGFLVWRRCRRREKF 110
           P +DFCLG A            +P  +L  I  GAL    ++G+L  F+  R  + R+  
Sbjct: 9   PQADFCLGTALHSWGLWFTEEGSPSTMLTGIAVGALLALALVGVLILFMFRRLRQFRQAQ 68

Query: 111 TTP 113
            TP
Sbjct: 69  PTP 71


>gi|88758613 CD93 antigen precursor [Homo sapiens]
          Length = 652

 Score = 26.6 bits (57), Expect = 5.8
 Identities = 15/35 (42%), Positives = 22/35 (62%), Gaps = 2/35 (5%)

Query: 77  LLWPILGGALSLTFVLGLLSGFLVW--RRCRRREK 109
           LL+ ILG  +++  +L L  G LV+  RR +R EK
Sbjct: 582 LLFYILGTVVAILLLLALALGLLVYRKRRAKREEK 616


>gi|14589891 cadherin 3, type 1 preproprotein [Homo sapiens]
          Length = 829

 Score = 26.6 bits (57), Expect = 5.8
 Identities = 17/56 (30%), Positives = 30/56 (53%), Gaps = 3/56 (5%)

Query: 64  CLGCAAAPPAPFR--LLWPILGGALSLTFVLGLLSGFLVWRRCRRREKFTTPIEET 117
           C G     P P++   + P+LG  L+L F+L L+   LV ++ + +E    P ++T
Sbjct: 640 CHGHVETCPGPWKGGFILPVLGAVLALLFLL-LVLLLLVRKKRKIKEPLLLPEDDT 694


>gi|71043500 beta
          1,4-N-acetylgalactosaminyltransferase-transferase 3
          [Homo sapiens]
          Length = 998

 Score = 26.2 bits (56), Expect = 7.6
 Identities = 23/65 (35%), Positives = 28/65 (43%), Gaps = 8/65 (12%)

Query: 6  LRRLLRLLV------LGLWLALLRSVAGEQAPGTAPCSRGSSWSADLDKCMDCASCRA-R 58
          LRR  RLL+      +GLW   L  VA  Q  G     R  SW  +L K +   +  A  
Sbjct: 19 LRRRFRLLLALAVVSVGLWTLYLELVASAQVGGNPLNRRYGSW-RELAKALASRNIPAVD 77

Query: 59 PHSDF 63
          PH  F
Sbjct: 78 PHLQF 82


>gi|93204881 Rab interacting lysosomal protein [Homo sapiens]
          Length = 401

 Score = 26.2 bits (56), Expect = 7.6
 Identities = 17/58 (29%), Positives = 21/58 (36%), Gaps = 1/58 (1%)

Query: 16  GLWLALLRSVAGEQAPGTAPCSRGSSWSADLDKCMDCASCRARPHSDFCLGCAAAPPA 73
           GLW       + ++    AP   G    A          C A  H   CLG +AAP A
Sbjct: 345 GLWYRGKAESSEDETSSPAPSKLGGEEEAQPQSPAPDPPCSAL-HEHLCLGASAAPEA 401


>gi|110347437 latent transforming growth factor beta binding protein 4
            isoform c [Homo sapiens]
          Length = 1557

 Score = 26.2 bits (56), Expect = 7.6
 Identities = 16/45 (35%), Positives = 19/45 (42%), Gaps = 12/45 (26%)

Query: 36   CSRGSSWSADLDKCMDCASCRARPHSDFCLGC------AAAPPAP 74
            C  G +W       MDCA C A+   DF   C      A +PP P
Sbjct: 1310 CLYGEAWG------MDCALCPAQDSDDFEALCNVLRPPAYSPPRP 1348


>gi|110347412 latent transforming growth factor beta binding protein 4
            isoform b [Homo sapiens]
          Length = 1587

 Score = 26.2 bits (56), Expect = 7.6
 Identities = 16/45 (35%), Positives = 19/45 (42%), Gaps = 12/45 (26%)

Query: 36   CSRGSSWSADLDKCMDCASCRARPHSDFCLGC------AAAPPAP 74
            C  G +W       MDCA C A+   DF   C      A +PP P
Sbjct: 1340 CLYGEAWG------MDCALCPAQDSDDFEALCNVLRPPAYSPPRP 1378


>gi|110347431 latent transforming growth factor beta binding protein 4
            isoform a [Homo sapiens]
          Length = 1624

 Score = 26.2 bits (56), Expect = 7.6
 Identities = 16/45 (35%), Positives = 19/45 (42%), Gaps = 12/45 (26%)

Query: 36   CSRGSSWSADLDKCMDCASCRARPHSDFCLGC------AAAPPAP 74
            C  G +W       MDCA C A+   DF   C      A +PP P
Sbjct: 1377 CLYGEAWG------MDCALCPAQDSDDFEALCNVLRPPAYSPPRP 1415


>gi|21281681 leucine-rich repeat LGI family, member 3 [Homo
          sapiens]
          Length = 548

 Score = 26.2 bits (56), Expect = 7.6
 Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 2/43 (4%)

Query: 9  LLRLLVLGLWLALLRSVAGEQAPGTAPCSRGSSWSADLDKCMD 51
          LL L  LG  L L   V+ ++ P T PC    S + D   C+D
Sbjct: 14 LLALSALGFCLML--QVSAKRPPKTPPCPPSCSCTRDTAFCVD 54


>gi|167614500 lymphocyte-activation protein 3 precursor [Homo
           sapiens]
          Length = 525

 Score = 26.2 bits (56), Expect = 7.6
 Identities = 18/42 (42%), Positives = 24/42 (57%), Gaps = 1/42 (2%)

Query: 70  APPAPFRLLWPILGGALSLTFVLGLLSGFLVWRRCRRREKFT 111
           A PA   LL+ ILG  LSL  ++    GF +WRR  R  +F+
Sbjct: 444 ALPAGHLLLFLILG-VLSLLLLVTGAFGFHLWRRQWRPRRFS 484


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.141    0.476 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,002,594
Number of Sequences: 37866
Number of extensions: 268783
Number of successful extensions: 1126
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 1104
Number of HSP's gapped (non-prelim): 48
length of query: 129
length of database: 18,247,518
effective HSP length: 90
effective length of query: 39
effective length of database: 14,839,578
effective search space: 578743542
effective search space used: 578743542
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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