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Search of human proteins with 7706135
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7706135 potassium channel, subfamily K, member 9 [Homo
sapiens]
(374 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7706135 potassium channel, subfamily K, member 9 [Homo sapiens] 755 0.0
gi|4504849 potassium channel, subfamily K, member 3 [Homo sapiens] 428 e-120
gi|11641275 potassium family, subfamily K, member 15 [Homo sapiens] 339 3e-93
gi|205360983 potassium channel, subfamily K, member 16 isoform 3... 131 1e-30
gi|14149764 potassium channel, subfamily K, member 16 isoform 2 ... 131 1e-30
gi|16306555 potassium channel, subfamily K, member 13 [Homo sapi... 129 6e-30
gi|205360973 potassium channel, subfamily K, member 16 isoform 4... 126 4e-29
gi|205360971 potassium channel, subfamily K, member 16 isoform 1... 126 4e-29
gi|14589851 potassium channel, subfamily K, member 2 isoform b [... 125 5e-29
gi|126365795 potassium channel, subfamily K, member 2 isoform c ... 125 5e-29
gi|62912487 potassium channel, subfamily K, member 2 isoform a [... 125 5e-29
gi|20143946 potassium channel, subfamily K, member 10 isoform 3 ... 124 1e-28
gi|20143944 potassium channel, subfamily K, member 10 isoform 2 ... 124 1e-28
gi|10863961 potassium channel, subfamily K, member 10 isoform 1 ... 124 1e-28
gi|15718767 TRAAK [Homo sapiens] 120 2e-27
gi|4504847 potassium channel, subfamily K, member 1 [Homo sapiens] 117 2e-26
gi|4504851 potassium channel, subfamily K, member 5 [Homo sapiens] 116 3e-26
gi|4758624 potassium channel, subfamily K, member 6 [Homo sapiens] 108 1e-23
gi|17025230 potassium channel, subfamily K, member 17 isoform 1 ... 105 7e-23
gi|11545761 potassium channel, subfamily K, member 12 [Homo sapi... 102 4e-22
gi|205361107 potassium channel, subfamily K, member 17 isoform 2... 101 1e-21
gi|5031821 potassium channel, subfamily K, member 7 isoform C [H... 75 1e-13
gi|16118231 potassium channel, subfamily K, member 7 isoform A [... 75 1e-13
gi|16118235 potassium channel, subfamily K, member 7 isoform B [... 75 1e-13
gi|16118233 potassium channel, subfamily K, member 7 isoform B [... 75 1e-13
gi|32469495 potassium channel, subfamily K, member 18 [Homo sapi... 72 1e-12
gi|22024390 potassium voltage-gated channel, subfamily H, member... 39 0.006
gi|27886648 potassium voltage-gated channel, subfamily H, member... 39 0.006
gi|27886646 potassium voltage-gated channel, subfamily H, member... 39 0.006
gi|4504831 potassium voltage-gated channel, subfamily H, member ... 38 0.013
>gi|7706135 potassium channel, subfamily K, member 9 [Homo sapiens]
Length = 374
Score = 755 bits (1950), Expect = 0.0
Identities = 374/374 (100%), Positives = 374/374 (100%)
Query: 1 MKRQNVRTLSLIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYR 60
MKRQNVRTLSLIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYR
Sbjct: 1 MKRQNVRTLSLIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYR 60
Query: 61 QLELVILQSEPHRAGVQWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPL 120
QLELVILQSEPHRAGVQWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPL
Sbjct: 61 QLELVILQSEPHRAGVQWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPL 120
Query: 121 TLVMFQSLGERMNTFVRYLLKRIKKCCGMRNTDVSMENMVTVGFFSCMGTLCIGAAAFSQ 180
TLVMFQSLGERMNTFVRYLLKRIKKCCGMRNTDVSMENMVTVGFFSCMGTLCIGAAAFSQ
Sbjct: 121 TLVMFQSLGERMNTFVRYLLKRIKKCCGMRNTDVSMENMVTVGFFSCMGTLCIGAAAFSQ 180
Query: 181 CEEWSFFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSFMYILVGLTVIGAFLN 240
CEEWSFFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSFMYILVGLTVIGAFLN
Sbjct: 181 CEEWSFFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSFMYILVGLTVIGAFLN 240
Query: 241 LVVLRFLTMNSEDERRDAEERASLAGNRNSMVIHIPEEPRPSRPRYKADVPDLQSVCSCT 300
LVVLRFLTMNSEDERRDAEERASLAGNRNSMVIHIPEEPRPSRPRYKADVPDLQSVCSCT
Sbjct: 241 LVVLRFLTMNSEDERRDAEERASLAGNRNSMVIHIPEEPRPSRPRYKADVPDLQSVCSCT 300
Query: 301 CYRSQDYGGRSVAPQNSFSAKLAPHYFHSISYKIEEISPSTLKNSLFPSPISSISPGLHS 360
CYRSQDYGGRSVAPQNSFSAKLAPHYFHSISYKIEEISPSTLKNSLFPSPISSISPGLHS
Sbjct: 301 CYRSQDYGGRSVAPQNSFSAKLAPHYFHSISYKIEEISPSTLKNSLFPSPISSISPGLHS 360
Query: 361 FTDHQRLMKRRKSV 374
FTDHQRLMKRRKSV
Sbjct: 361 FTDHQRLMKRRKSV 374
>gi|4504849 potassium channel, subfamily K, member 3 [Homo sapiens]
Length = 394
Score = 428 bits (1101), Expect = e-120
Identities = 231/394 (58%), Positives = 275/394 (69%), Gaps = 20/394 (5%)
Query: 1 MKRQNVRTLSLIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYR 60
MKRQNVRTL+LIVCTFTYLLVGAAVFDALES+ E+ E ++L+ + ++ +YN+S Y
Sbjct: 1 MKRQNVRTLALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQELRARYNLSQGGYE 60
Query: 61 QLELVILQSEPHRAGVQWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPL 120
+LE V+L+ +PH+AGVQW+FAGSFYFAITVITTIGYGHAAP TD GK FCMFYA+LGIPL
Sbjct: 61 ELERVVLRLKPHKAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPL 120
Query: 121 TLVMFQSLGERMNTFVRYLLKRIKKCCGMRNTDVSMENMVTVGFFSCMGTLCIGAAAFSQ 180
TLVMFQSLGER+NT VRYLL R KK GMR DVSM NMV +GFFSC+ TLCIGAAAFS
Sbjct: 121 TLVMFQSLGERINTLVRYLLHRAKKGLGMRRADVSMANMVLIGFFSCISTLCIGAAAFSH 180
Query: 181 CEEWSFFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSFMYILVGLTVIGAFLN 240
E W+FF AYYYCFITLTTIGFGDYVALQ ALQ +P YVAFSF+YIL GLTVIGAFLN
Sbjct: 181 YEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLN 240
Query: 241 LVVLRFLTMNSEDERRDAEERASLA------GNRNSMVIHIPEEPRPSRP-------RYK 287
LVVLRF+TMN+EDE+RDAE RA L G H + +
Sbjct: 241 LVVLRFMTMNAEDEKRDAEHRALLTRNGQAGGGGGGGSAHTTDTASSTAAAGGGGFRNVY 300
Query: 288 ADVPDLQSVCSCTCYRSQD---YGGRSVAPQNSFSAKLAPHYFHSISYKIEEISPSTLKN 344
A+V QS+CSC Y+S++ Y + P++ ++ HS S + +
Sbjct: 301 AEVLHFQSMCSCLWYKSREKLQYSIPMIIPRDLSTSDTCVEQSHSSPGGGGRYSDTPSRR 360
Query: 345 SLFP----SPISSISPGLHSFTDHQRLMKRRKSV 374
L S ISS+S GLHS + + LMKRR SV
Sbjct: 361 CLCSGAPRSAISSVSTGLHSLSTFRGLMKRRSSV 394
>gi|11641275 potassium family, subfamily K, member 15 [Homo sapiens]
Length = 330
Score = 339 bits (869), Expect = 3e-93
Identities = 175/283 (61%), Positives = 207/283 (73%), Gaps = 1/283 (0%)
Query: 1 MKRQNVRTLSLIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYR 60
M+R +VR L++CT YLLVGAAVFDALES+ E + L + ++ K+ S+EDYR
Sbjct: 1 MRRPSVRAAGLVLCTLCYLLVGAAVFDALESEAESGRQRLLVQKRGALRRKFGFSAEDYR 60
Query: 61 QLELVILQSEPHRAGVQWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPL 120
+LE + LQ+EPHRAG QWKF GSFYFAITVITTIGYGHAAPGTD+GK FCMFYA+LGIPL
Sbjct: 61 ELERLALQAEPHRAGRQWKFPGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGIPL 120
Query: 121 TLVMFQSLGERMNTFVRYLLKRIKKCCGMRNTDVSMENMVTVGFFSCMGTLCIGAAAFSQ 180
TLV FQSLGER+N VR LL K C G+R T VS EN+V G +C TL +GA AFS
Sbjct: 121 TLVTFQSLGERLNAVVRRLLLAAKCCLGLRWTCVSTENLVVAGLLACAATLALGAVAFSH 180
Query: 181 CEEWSFFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSFMYILVGLTVIGAFLN 240
E W+FFHAYYYCFITLTTIGFGD+VALQ+ ALQ+K YVAFSF+YIL+GLTVIGAFLN
Sbjct: 181 FEGWTFFHAYYYCFITLTTIGFGDFVALQSGEALQRKLPYVAFSFLYILLGLTVIGAFLN 240
Query: 241 LVVLRFLTMNSE-DERRDAEERASLAGNRNSMVIHIPEEPRPS 282
LVVLRFL +++ ER G S + +P P S
Sbjct: 241 LVVLRFLVASADWPERAARPPSPRPPGAPESRGLWLPRRPARS 283
>gi|205360983 potassium channel, subfamily K, member 16 isoform 3
[Homo sapiens]
Length = 294
Score = 131 bits (329), Expect = 1e-30
Identities = 87/248 (35%), Positives = 130/248 (52%), Gaps = 20/248 (8%)
Query: 7 RTLSLIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYRQLELVI 66
R L L++ YLL+GA +F LE E + ++ + E++R Y + + + V
Sbjct: 13 RVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQ-WAMEQFVQ 71
Query: 67 LQSEPHRAGVQ----------WKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVL 116
+ E GV W F SF+FA TV+TTIGYG+ AP T+AG+ FC+FYA+L
Sbjct: 72 VIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALL 131
Query: 117 GIPLTLVMFQSLGERMNTFVRYLLKRIKKCCGMRNTDVSMENMVTVGFFSCMGTLCI--- 173
GIPL ++ LG T +R L I++ R + ++ + F +GTL I
Sbjct: 132 GIPLNVIFLNHLG----TGLRAHLAAIER-WEDRPRRSQVLQVLGLALFLTLGTLVILIF 186
Query: 174 GAAAFSQCEEWSFFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSFMYILVGLT 233
FS E WSF +Y+ FITL+TIGFGDYV + T + +Y + + ++IL+GL
Sbjct: 187 PPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYV-VGTDPSKHYISVYRSLAAIWILLGLA 245
Query: 234 VIGAFLNL 241
+ L L
Sbjct: 246 WLALILPL 253
>gi|14149764 potassium channel, subfamily K, member 16 isoform 2
[Homo sapiens]
Length = 309
Score = 131 bits (329), Expect = 1e-30
Identities = 87/248 (35%), Positives = 130/248 (52%), Gaps = 20/248 (8%)
Query: 7 RTLSLIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYRQLELVI 66
R L L++ YLL+GA +F LE E + ++ + E++R Y + + + V
Sbjct: 13 RVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQ-WAMEQFVQ 71
Query: 67 LQSEPHRAGVQ----------WKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVL 116
+ E GV W F SF+FA TV+TTIGYG+ AP T+AG+ FC+FYA+L
Sbjct: 72 VIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALL 131
Query: 117 GIPLTLVMFQSLGERMNTFVRYLLKRIKKCCGMRNTDVSMENMVTVGFFSCMGTLCI--- 173
GIPL ++ LG T +R L I++ R + ++ + F +GTL I
Sbjct: 132 GIPLNVIFLNHLG----TGLRAHLAAIER-WEDRPRRSQVLQVLGLALFLTLGTLVILIF 186
Query: 174 GAAAFSQCEEWSFFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSFMYILVGLT 233
FS E WSF +Y+ FITL+TIGFGDYV + T + +Y + + ++IL+GL
Sbjct: 187 PPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYV-VGTDPSKHYISVYRSLAAIWILLGLA 245
Query: 234 VIGAFLNL 241
+ L L
Sbjct: 246 WLALILPL 253
>gi|16306555 potassium channel, subfamily K, member 13 [Homo
sapiens]
Length = 408
Score = 129 bits (323), Expect = 6e-30
Identities = 80/270 (29%), Positives = 131/270 (48%), Gaps = 31/270 (11%)
Query: 1 MKRQNVRTLSLIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYR 60
+ N R L L YLL GAAVF ALE HE + +++ + +N+S ++ R
Sbjct: 13 LNEDNARFLLLAALIVLYLLGGAAVFSALELAHERQAKQRWEERLANFSRGHNLSRDELR 72
Query: 61 QLELVILQSEPHRAGVQ-------WKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFY 113
+ E RAG++ W F G+FYF TV++TIG+G P T GK F +FY
Sbjct: 73 GF--LRHYEEATRAGIRVDNVRPRWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFY 130
Query: 114 AVLGIPLTLVMFQSLGERMNTFVRYLLKRIKKCCGMRNTDVSMENMVTVG---------- 163
++G T++ F ER+ T + Y++K + R + E++ G
Sbjct: 131 GLVGCSSTILFFNLFLERLITIIAYIMKSCHQRQLRRRGALPQESLKDAGQCEVDSLAGW 190
Query: 164 --------FFSCMGTL---CIGAAAFSQCEEWSFFHAYYYCFITLTTIGFGDYVALQTKG 212
C ++ C +A ++ E WS+F + Y+CF+ +TIGFGD V+ Q
Sbjct: 191 KPSVYYVMLILCTASILISCCASAMYTPIEGWSYFDSLYFCFVAFSTIGFGDLVSSQ-NA 249
Query: 213 ALQKKPLYVAFSFMYILVGLTVIGAFLNLV 242
+ + LY +F++IL+G+ I + N++
Sbjct: 250 HYESQGLYRFANFVFILMGVCCIYSLFNVI 279
>gi|205360973 potassium channel, subfamily K, member 16 isoform 4
[Homo sapiens]
Length = 262
Score = 126 bits (316), Expect = 4e-29
Identities = 79/213 (37%), Positives = 113/213 (53%), Gaps = 19/213 (8%)
Query: 7 RTLSLIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYRQLELVI 66
R L L++ YLL+GA +F LE E + ++ + E++R Y + + + V
Sbjct: 13 RVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQ-WAMEQFVQ 71
Query: 67 LQSEPHRAGVQ----------WKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVL 116
+ E GV W F SF+FA TV+TTIGYG+ AP T+AG+ FC+FYA+L
Sbjct: 72 VIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALL 131
Query: 117 GIPLTLVMFQSLGERMNTFVRYLLKRIKKCCGMRNTDVSMENMVTVGFFSCMGTLCI--- 173
GIPL ++ LG T +R L I++ R + ++ + F +GTL I
Sbjct: 132 GIPLNVIFLNHLG----TGLRAHLAAIER-WEDRPRRSQVLQVLGLALFLTLGTLVILIF 186
Query: 174 GAAAFSQCEEWSFFHAYYYCFITLTTIGFGDYV 206
FS E WSF +Y+ FITL+TIGFGDYV
Sbjct: 187 PPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYV 219
Score = 30.8 bits (68), Expect = 2.1
Identities = 12/29 (41%), Positives = 16/29 (55%)
Query: 78 WKFAGSFYFAITVITTIGYGHAAPGTDAG 106
W F+ FYFA ++TIG+G G G
Sbjct: 197 WSFSEGFYFAFITLSTIGFGDYVVGLRQG 225
>gi|205360971 potassium channel, subfamily K, member 16 isoform 1
[Homo sapiens]
Length = 322
Score = 126 bits (316), Expect = 4e-29
Identities = 79/213 (37%), Positives = 113/213 (53%), Gaps = 19/213 (8%)
Query: 7 RTLSLIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYRQLELVI 66
R L L++ YLL+GA +F LE E + ++ + E++R Y + + + V
Sbjct: 13 RVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQ-WAMEQFVQ 71
Query: 67 LQSEPHRAGVQ----------WKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVL 116
+ E GV W F SF+FA TV+TTIGYG+ AP T+AG+ FC+FYA+L
Sbjct: 72 VIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALL 131
Query: 117 GIPLTLVMFQSLGERMNTFVRYLLKRIKKCCGMRNTDVSMENMVTVGFFSCMGTLCI--- 173
GIPL ++ LG T +R L I++ R + ++ + F +GTL I
Sbjct: 132 GIPLNVIFLNHLG----TGLRAHLAAIER-WEDRPRRSQVLQVLGLALFLTLGTLVILIF 186
Query: 174 GAAAFSQCEEWSFFHAYYYCFITLTTIGFGDYV 206
FS E WSF +Y+ FITL+TIGFGDYV
Sbjct: 187 PPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYV 219
Score = 30.0 bits (66), Expect = 3.5
Identities = 11/25 (44%), Positives = 15/25 (60%)
Query: 78 WKFAGSFYFAITVITTIGYGHAAPG 102
W F+ FYFA ++TIG+G G
Sbjct: 197 WSFSEGFYFAFITLSTIGFGDYVVG 221
>gi|14589851 potassium channel, subfamily K, member 2 isoform b
[Homo sapiens]
Length = 411
Score = 125 bits (315), Expect = 5e-29
Identities = 89/307 (28%), Positives = 151/307 (49%), Gaps = 25/307 (8%)
Query: 1 MKRQNVRTLSLIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYN-ISSEDY 59
MK + V T+ L+V YL++GA VF ALE HE+ + + ++ +++ ++S +
Sbjct: 42 MKWKTVSTIFLVVVL--YLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTEL 99
Query: 60 RQLELVILQSEPHRAGV-----------QWKFAGSFYFAITVITTIGYGHAAPGTDAGKA 108
+L I+ + AG+ W SF+FA TVITTIG+G+ +P T+ GK
Sbjct: 100 DELIQQIVAAI--NAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKI 157
Query: 109 FCMFYAVLGIPLTLVMFQSLGERMNTFVRYLLKRIKKC---CGMRNTDVSMENMVTVGFF 165
FC+ YA+LGIPL + +G+++ T + +++ + T + + + + F
Sbjct: 158 FCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILF 217
Query: 166 SCMGTLCIGAAAFSQCEEWSFFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSF 225
C+ + + A F E WS A Y+ ITLTTIGFGDYVA ++ Y +
Sbjct: 218 GCVLFVALPAIIFKHIEGWSALDAIYFVVITLTTIGFGDYVA--GGSDIEYLDFYKPVVW 275
Query: 226 MYILVGLTVIGAFLNLVVLRFLTMNSEDERRDAEERASLAGNRNSMVIHIPEEPRPSRPR 285
+ILVGL A L+++ ++ + + E RA A ++ E + +R R
Sbjct: 276 FWILVGLAYFAAVLSMIGDWLRVISKKTKEEVGEFRAHAA----EWTANVTAEFKETRRR 331
Query: 286 YKADVPD 292
++ D
Sbjct: 332 LSVEIYD 338
>gi|126365795 potassium channel, subfamily K, member 2 isoform c
[Homo sapiens]
Length = 426
Score = 125 bits (315), Expect = 5e-29
Identities = 89/307 (28%), Positives = 151/307 (49%), Gaps = 25/307 (8%)
Query: 1 MKRQNVRTLSLIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYN-ISSEDY 59
MK + V T+ L+V YL++GA VF ALE HE+ + + ++ +++ ++S +
Sbjct: 57 MKWKTVSTIFLVVVL--YLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTEL 114
Query: 60 RQLELVILQSEPHRAGV-----------QWKFAGSFYFAITVITTIGYGHAAPGTDAGKA 108
+L I+ + AG+ W SF+FA TVITTIG+G+ +P T+ GK
Sbjct: 115 DELIQQIVAAI--NAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKI 172
Query: 109 FCMFYAVLGIPLTLVMFQSLGERMNTFVRYLLKRIKKC---CGMRNTDVSMENMVTVGFF 165
FC+ YA+LGIPL + +G+++ T + +++ + T + + + + F
Sbjct: 173 FCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILF 232
Query: 166 SCMGTLCIGAAAFSQCEEWSFFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSF 225
C+ + + A F E WS A Y+ ITLTTIGFGDYVA ++ Y +
Sbjct: 233 GCVLFVALPAIIFKHIEGWSALDAIYFVVITLTTIGFGDYVA--GGSDIEYLDFYKPVVW 290
Query: 226 MYILVGLTVIGAFLNLVVLRFLTMNSEDERRDAEERASLAGNRNSMVIHIPEEPRPSRPR 285
+ILVGL A L+++ ++ + + E RA A ++ E + +R R
Sbjct: 291 FWILVGLAYFAAVLSMIGDWLRVISKKTKEEVGEFRAHAA----EWTANVTAEFKETRRR 346
Query: 286 YKADVPD 292
++ D
Sbjct: 347 LSVEIYD 353
>gi|62912487 potassium channel, subfamily K, member 2 isoform a
[Homo sapiens]
Length = 422
Score = 125 bits (315), Expect = 5e-29
Identities = 89/307 (28%), Positives = 151/307 (49%), Gaps = 25/307 (8%)
Query: 1 MKRQNVRTLSLIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYN-ISSEDY 59
MK + V T+ L+V YL++GA VF ALE HE+ + + ++ +++ ++S +
Sbjct: 53 MKWKTVSTIFLVVVL--YLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTEL 110
Query: 60 RQLELVILQSEPHRAGV-----------QWKFAGSFYFAITVITTIGYGHAAPGTDAGKA 108
+L I+ + AG+ W SF+FA TVITTIG+G+ +P T+ GK
Sbjct: 111 DELIQQIVAAI--NAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKI 168
Query: 109 FCMFYAVLGIPLTLVMFQSLGERMNTFVRYLLKRIKKC---CGMRNTDVSMENMVTVGFF 165
FC+ YA+LGIPL + +G+++ T + +++ + T + + + + F
Sbjct: 169 FCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILF 228
Query: 166 SCMGTLCIGAAAFSQCEEWSFFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSF 225
C+ + + A F E WS A Y+ ITLTTIGFGDYVA ++ Y +
Sbjct: 229 GCVLFVALPAIIFKHIEGWSALDAIYFVVITLTTIGFGDYVA--GGSDIEYLDFYKPVVW 286
Query: 226 MYILVGLTVIGAFLNLVVLRFLTMNSEDERRDAEERASLAGNRNSMVIHIPEEPRPSRPR 285
+ILVGL A L+++ ++ + + E RA A ++ E + +R R
Sbjct: 287 FWILVGLAYFAAVLSMIGDWLRVISKKTKEEVGEFRAHAA----EWTANVTAEFKETRRR 342
Query: 286 YKADVPD 292
++ D
Sbjct: 343 LSVEIYD 349
>gi|20143946 potassium channel, subfamily K, member 10 isoform 3
[Homo sapiens]
Length = 543
Score = 124 bits (312), Expect = 1e-28
Identities = 85/301 (28%), Positives = 145/301 (48%), Gaps = 26/301 (8%)
Query: 9 LSLIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYRQLELVILQ 68
+++ V YL+ G VF ALE E ++ + E+ + S ++LE +I
Sbjct: 78 VAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSP--QELETLIQH 135
Query: 69 S-EPHRAGVQ-----------WKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVL 116
+ + AGV W +F+FA TVITTIGYG+ AP T+ GK FC+ YA+
Sbjct: 136 ALDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIF 195
Query: 117 GIPLTLVMFQSLGERMNTFVRYLLKRIKKCCGMRNTDVSMENMVTVGFF---SCMGTLCI 173
GIPL + +G+++ T + R++K + + +++ F C+ + I
Sbjct: 196 GIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTI 255
Query: 174 GAAAFSQCEEWSFFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSFMYILVGLT 233
A F E W+ + Y+ +TLTT+GFGD+VA G + + Y + +ILVGL
Sbjct: 256 PAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAG-INYREWYKPLVWFWILVGLA 314
Query: 234 VIGAFLNLV--VLRFLTMNSEDERRDAEERASLAGNRNSMVIHIPEEPRPSRPRYKADVP 291
A L+++ LR L+ +++E + + A+ ++ E R +R R ++
Sbjct: 315 YFAAVLSMIGDWLRVLSKKTKEEVGEIKAHAA------EWKANVTAEFRETRRRLSVEIH 368
Query: 292 D 292
D
Sbjct: 369 D 369
>gi|20143944 potassium channel, subfamily K, member 10 isoform 2
[Homo sapiens]
Length = 543
Score = 124 bits (312), Expect = 1e-28
Identities = 85/301 (28%), Positives = 145/301 (48%), Gaps = 26/301 (8%)
Query: 9 LSLIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYRQLELVILQ 68
+++ V YL+ G VF ALE E ++ + E+ + S ++LE +I
Sbjct: 78 VAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSP--QELETLIQH 135
Query: 69 S-EPHRAGVQ-----------WKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVL 116
+ + AGV W +F+FA TVITTIGYG+ AP T+ GK FC+ YA+
Sbjct: 136 ALDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIF 195
Query: 117 GIPLTLVMFQSLGERMNTFVRYLLKRIKKCCGMRNTDVSMENMVTVGFF---SCMGTLCI 173
GIPL + +G+++ T + R++K + + +++ F C+ + I
Sbjct: 196 GIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTI 255
Query: 174 GAAAFSQCEEWSFFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSFMYILVGLT 233
A F E W+ + Y+ +TLTT+GFGD+VA G + + Y + +ILVGL
Sbjct: 256 PAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAG-INYREWYKPLVWFWILVGLA 314
Query: 234 VIGAFLNLV--VLRFLTMNSEDERRDAEERASLAGNRNSMVIHIPEEPRPSRPRYKADVP 291
A L+++ LR L+ +++E + + A+ ++ E R +R R ++
Sbjct: 315 YFAAVLSMIGDWLRVLSKKTKEEVGEIKAHAA------EWKANVTAEFRETRRRLSVEIH 368
Query: 292 D 292
D
Sbjct: 369 D 369
>gi|10863961 potassium channel, subfamily K, member 10 isoform 1
[Homo sapiens]
Length = 538
Score = 124 bits (312), Expect = 1e-28
Identities = 85/301 (28%), Positives = 145/301 (48%), Gaps = 26/301 (8%)
Query: 9 LSLIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYRQLELVILQ 68
+++ V YL+ G VF ALE E ++ + E+ + S ++LE +I
Sbjct: 73 VAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSP--QELETLIQH 130
Query: 69 S-EPHRAGVQ-----------WKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVL 116
+ + AGV W +F+FA TVITTIGYG+ AP T+ GK FC+ YA+
Sbjct: 131 ALDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIF 190
Query: 117 GIPLTLVMFQSLGERMNTFVRYLLKRIKKCCGMRNTDVSMENMVTVGFF---SCMGTLCI 173
GIPL + +G+++ T + R++K + + +++ F C+ + I
Sbjct: 191 GIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTI 250
Query: 174 GAAAFSQCEEWSFFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSFMYILVGLT 233
A F E W+ + Y+ +TLTT+GFGD+VA G + + Y + +ILVGL
Sbjct: 251 PAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAG-INYREWYKPLVWFWILVGLA 309
Query: 234 VIGAFLNLV--VLRFLTMNSEDERRDAEERASLAGNRNSMVIHIPEEPRPSRPRYKADVP 291
A L+++ LR L+ +++E + + A+ ++ E R +R R ++
Sbjct: 310 YFAAVLSMIGDWLRVLSKKTKEEVGEIKAHAA------EWKANVTAEFRETRRRLSVEIH 363
Query: 292 D 292
D
Sbjct: 364 D 364
>gi|15718767 TRAAK [Homo sapiens]
Length = 393
Score = 120 bits (302), Expect = 2e-27
Identities = 83/261 (31%), Positives = 130/261 (49%), Gaps = 28/261 (10%)
Query: 9 LSLIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYRQLELVILQ 68
L+L+ YL+ GA VF ALE HE + + +L E+R K ++L L+I +
Sbjct: 7 LALLALVLLYLVSGALVFRALEQPHEQQAQRELG--EVREKFLRAHPCVSDQELGLLIKE 64
Query: 69 --------------SEPHRAGVQWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYA 114
S + + W +F+F+ T+ITTIGYG+ A TDAG+ FC+FYA
Sbjct: 65 VADALGGGADPETNSTSNSSHSAWDLGSAFFFSGTIITTIGYGNVALRTDAGRLFCIFYA 124
Query: 115 VLGIPLTLVMFQSLGERMNTFVRYLLKRIKKCCGMRNTDVSMENMVTVGFFSCMGTLCI- 173
++GIPL ++ +G+R+ + +R+ + I+ + + +++ F +G L
Sbjct: 125 LVGIPLFGILLAGVGDRLGSSLRHGIGHIEAIFLKWHVPPELVRVLSAMLFLLIGCLLFV 184
Query: 174 --GAAAFSQCEEWSFFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSFMYILVG 231
F E+WS A Y+ +TLTT+GFGDYVA Q P Y + +IL+G
Sbjct: 185 LTPTFVFCYMEDWSKLEAIYFVIVTLTTVGFGDYVA--GADPRQDSPAYQPLVWFWILLG 242
Query: 232 -------LTVIGAFLNLVVLR 245
LT IG +L +V R
Sbjct: 243 LAYFASVLTTIGNWLRVVSRR 263
>gi|4504847 potassium channel, subfamily K, member 1 [Homo sapiens]
Length = 336
Score = 117 bits (293), Expect = 2e-26
Identities = 80/236 (33%), Positives = 127/236 (53%), Gaps = 18/236 (7%)
Query: 11 LIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYRQLELV---IL 67
L++ YL+ GA VF ++E +E ++L+ + R ++ SE +QLE +L
Sbjct: 26 LVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKLKRRFLEEHECLSE--QQLEQFLGRVL 83
Query: 68 QSEPHRAGV--------QWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIP 119
++ + V W F + +FA TV++T GYGH P +D GKAFC+ Y+V+GIP
Sbjct: 84 EASNYGVSVLSNASGNWNWDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIGIP 143
Query: 120 LTLVMFQSLGERMNTFV-RYLLKRIKKCCGMRNTDVSMENMVTVGFFSCMGTLCIGAAAF 178
TL+ ++ +R+ V R + G V++ + V +GF + I AA F
Sbjct: 144 FTLLFLTAVVQRITVHVTRRPVLYFHIRWGFSKQVVAIVHAVLLGFVTVSCFFFIPAAVF 203
Query: 179 SQCE-EWSFFHAYYYCFITLTTIGFGDYVALQTKGALQK-KPLYVAFSFMYILVGL 232
S E +W+F ++Y+CFI+L+TIG GDYV +G QK + LY Y+L+GL
Sbjct: 204 SVLEDDWNFLESFYFCFISLSTIGLGDYV--PGEGYNQKFRELYKIGITCYLLLGL 257
>gi|4504851 potassium channel, subfamily K, member 5 [Homo sapiens]
Length = 499
Score = 116 bits (291), Expect = 3e-26
Identities = 78/265 (29%), Positives = 125/265 (47%), Gaps = 18/265 (6%)
Query: 18 YLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYRQLELVILQSEPHRAGV- 76
YL +GAA+F+ LE H ++ +++ + ++ ++ L ++ S+ GV
Sbjct: 15 YLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEVV-SDAAGQGVA 73
Query: 77 --------QWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPLTLVMFQSL 128
W + + FA TVITTIGYG+ AP T AG+ FC+FY + G+PL L +L
Sbjct: 74 ITGNQTFNNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVPLCLTWISAL 133
Query: 129 GERMNTFVRYLLKRIKKCCGMRNTDVSMENMVTVGFFSCMGT---LCIGAAAFSQCEEWS 185
G+ F KR+ + R + + F G L I F E W+
Sbjct: 134 GK----FFGGRAKRLGQFLTKRGVSLRKAQITCTVIFIVWGVLVHLVIPPFVFMVTEGWN 189
Query: 186 FFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSFMYILVGLTVIGAFLNLVVLR 245
+ YY FIT++TIGFGD+VA A LY F ++I +GL + F+N V
Sbjct: 190 YIEGLYYSFITISTIGFGDFVAGVNPSA-NYHALYRYFVELWIYLGLAWLSLFVNWKVSM 248
Query: 246 FLTMNSEDERRDAEERASLAGNRNS 270
F+ ++ ++R + S + +S
Sbjct: 249 FVEVHKAIKKRRRRRKESFESSPHS 273
>gi|4758624 potassium channel, subfamily K, member 6 [Homo sapiens]
Length = 313
Score = 108 bits (269), Expect = 1e-23
Identities = 75/236 (31%), Positives = 124/236 (52%), Gaps = 21/236 (8%)
Query: 18 YLLVGAAVFDALESDHEMR---EEEKLKAEEIRIKGKYNISSEDY--------RQLELVI 66
YL++GA + LE HE R E E L+A+ ++ + D +L V+
Sbjct: 17 YLVLGALLVARLEGPHEARLRAELETLRAQLLQRSPCVAAPALDAFVERVLAAGRLGRVV 76
Query: 67 LQSEPHRAGVQ---WKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPLTLV 123
L + A W FA + +FA T+ITT+GYG+ P TDAGKAF + +A+LG+P T++
Sbjct: 77 LANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAGKAFSIAFALLGVPTTML 136
Query: 124 MFQSLGERMNTFVRYL-LKRIKKCCGMRNTDVSMENMVTVGFFSCMGTLC--IGAAAFSQ 180
+ + +R++ + ++ L + G + ++V + + T+C + A F+
Sbjct: 137 LLTASAQRLSLLLTHVPLSWLSMRWGWDPRRAACWHLVAL--LGVVVTVCFLVPAVIFAH 194
Query: 181 CEE-WSFFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSFMYILVGLTVI 235
EE WSF A+Y+CFI+L+TIG GDYV + G + LY +Y+ +GL +
Sbjct: 195 LEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPGQ-PYRALYKVLVTVYLFLGLVAM 249
>gi|17025230 potassium channel, subfamily K, member 17 isoform 1
[Homo sapiens]
Length = 332
Score = 105 bits (262), Expect = 7e-23
Identities = 73/260 (28%), Positives = 124/260 (47%), Gaps = 31/260 (11%)
Query: 8 TLSLIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYRQLELVI- 66
T+ L++ YL +G VF LE + ++ + N + D L+ +I
Sbjct: 22 TVLLLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKWELL--QNFTCLDRPALDSLIR 79
Query: 67 --LQSEPHRAGV--------QWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVL 116
+Q+ + A + +W+ GSF+F+++ ITTIGYG+ +P T A + FC+F+A++
Sbjct: 80 DVVQAYKNGASLLSNTTSMGRWELVGSFFFSVSTITTIGYGNLSPNTMAARLFCIFFALV 139
Query: 117 GIPLTLVMFQSLGERMNTFVRYLLKRI-------KKCCGMRNTDVSMENMVTVGFFSCMG 169
GIPL LV+ LG M V + R+ K + + + ++
Sbjct: 140 GIPLNLVVLNRLGHLMQQGVNHWASRLGGTWQDPDKARWLAGSGALLSGLLLF------- 192
Query: 170 TLCIGAAAFSQCEEWSFFHAYYYCFITLTTIGFGDYVALQTKGALQKKPL-YVAFSFMYI 228
L + FS E WS+ +Y+ FITL+T+GFGDYV Q+ PL Y ++I
Sbjct: 193 -LLLPPLLFSHMEGWSYTEGFYFAFITLSTVGFGDYVIGMNPS--QRYPLWYKNMVSLWI 249
Query: 229 LVGLTVIGAFLNLVVLRFLT 248
L G+ + + L++ + T
Sbjct: 250 LFGMAWLALIIKLILSQLET 269
>gi|11545761 potassium channel, subfamily K, member 12 [Homo
sapiens]
Length = 430
Score = 102 bits (255), Expect = 4e-22
Identities = 69/254 (27%), Positives = 121/254 (47%), Gaps = 33/254 (12%)
Query: 18 YLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYRQLELVILQSEPHRAGVQ 77
YL+ GA VF ALES E + A + ++ + R + AGV+
Sbjct: 49 YLVAGATVFSALESPGEAEARARWGATLRNFSAAHGVAEPELRAF--LRHYEAALAAGVR 106
Query: 78 -------WKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPLTLVMFQSLGE 130
W F G+FYF TV++TIG+G P T GKAF + Y + G T++ F E
Sbjct: 107 ADALRPRWDFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYGLFGCAGTILFFNLFLE 166
Query: 131 RMNTFVRYLLKRIKK----------CCGMRNTDVSMEN------------MVTVGFFSCM 168
R+ + + ++++ ++ R + +S + ++ +G F+ +
Sbjct: 167 RIISLLAFIMRACRERQLRRSGLLPATFRRGSALSEADSLAGWKPSVYHVLLILGLFAVL 226
Query: 169 GTLCIGAAAFSQCEEWSFFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSFMYI 228
C +A ++ E W + + Y+CF+T +TIGFGD V+ Q A + + LY +F++I
Sbjct: 227 -LSCCASAMYTSVEGWDYVDSLYFCFVTFSTIGFGDLVSSQ-HAAYRNQGLYRLGNFLFI 284
Query: 229 LVGLTVIGAFLNLV 242
L+G+ I + N++
Sbjct: 285 LLGVCCIYSLFNVI 298
Score = 32.0 bits (71), Expect = 0.93
Identities = 18/98 (18%), Positives = 38/98 (38%), Gaps = 12/98 (12%)
Query: 78 WKFAGSFYFAITVITTIGYGHAAPGTDAG-------KAFCMFYAVLGIPLTLVMFQSLGE 130
W + S YF +TIG+G A + + +LG+ +F +
Sbjct: 241 WDYVDSLYFCFVTFSTIGFGDLVSSQHAAYRNQGLYRLGNFLFILLGVCCIYSLFNVISI 300
Query: 131 RMNTFVRYLLKRIK-----KCCGMRNTDVSMENMVTVG 163
+ + ++L+++ +CC ++ N +T G
Sbjct: 301 LIKQVLNWMLRKLSCRCCARCCPAPGAPLARRNAITPG 338
Score = 29.6 bits (65), Expect = 4.6
Identities = 23/79 (29%), Positives = 34/79 (43%), Gaps = 8/79 (10%)
Query: 171 LCIGAAAFSQCEEWSFFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSFMYILV 230
L G A + W F A+Y+ ++TIGFG + T + K AF Y L
Sbjct: 101 LAAGVRADALRPRWDFPGAFYFVGTVVSTIGFG----MTTPATVGGK----AFLIAYGLF 152
Query: 231 GLTVIGAFLNLVVLRFLTM 249
G F NL + R +++
Sbjct: 153 GCAGTILFFNLFLERIISL 171
>gi|205361107 potassium channel, subfamily K, member 17 isoform 2
[Homo sapiens]
Length = 271
Score = 101 bits (251), Expect = 1e-21
Identities = 66/229 (28%), Positives = 110/229 (48%), Gaps = 28/229 (12%)
Query: 8 TLSLIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYRQLELVI- 66
T+ L++ YL +G VF LE + ++ + N + D L+ +I
Sbjct: 22 TVLLLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKWELL--QNFTCLDRPALDSLIR 79
Query: 67 --LQSEPHRAGV--------QWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVL 116
+Q+ + A + +W+ GSF+F+++ ITTIGYG+ +P T A + FC+F+A++
Sbjct: 80 DVVQAYKNGASLLSNTTSMGRWELVGSFFFSVSTITTIGYGNLSPNTMAARLFCIFFALV 139
Query: 117 GIPLTLVMFQSLGERMNTFVRYLLKRI-------KKCCGMRNTDVSMENMVTVGFFSCMG 169
GIPL LV+ LG M V + R+ K + + + ++
Sbjct: 140 GIPLNLVVLNRLGHLMQQGVNHWASRLGGTWQDPDKARWLAGSGALLSGLLLF------- 192
Query: 170 TLCIGAAAFSQCEEWSFFHAYYYCFITLTTIGFGDYVALQTKGALQKKP 218
L + FS E WS+ +Y+ FITL+T+GFGDYV + +KP
Sbjct: 193 -LLLPPLLFSHMEGWSYTEGFYFAFITLSTVGFGDYVIASCLISDTRKP 240
>gi|5031821 potassium channel, subfamily K, member 7 isoform C [Homo
sapiens]
Length = 257
Score = 75.1 bits (183), Expect = 1e-13
Identities = 56/205 (27%), Positives = 90/205 (43%), Gaps = 11/205 (5%)
Query: 11 LIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYRQLELV--ILQ 68
L+V L +GA VF ALE R + +L+AE + ++ EL+ L
Sbjct: 13 LVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGTALA 72
Query: 69 SEPHRA--------GVQWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPL 120
++ H G W + FA +++TT GYGH AP + GKAFCM YA LG+P
Sbjct: 73 TQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALGLPA 132
Query: 121 TLVMFQSLGERMNTFVRYLLKRIKKCCGMRNTDVSMENMVTVGFFSCMGTLCIGAAAFSQ 180
+L + +L + + + + ++ V +G + + A
Sbjct: 133 SLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVASSFVLLPALVLWG 192
Query: 181 CE-EWSFFHAYYYCFITLTTIGFGD 204
+ + S A Y+CF +L+TIG D
Sbjct: 193 LQGDCSLLGAVYFCFSSLSTIGLED 217
>gi|16118231 potassium channel, subfamily K, member 7 isoform A
[Homo sapiens]
Length = 307
Score = 75.1 bits (183), Expect = 1e-13
Identities = 56/205 (27%), Positives = 90/205 (43%), Gaps = 11/205 (5%)
Query: 11 LIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYRQLELV--ILQ 68
L+V L +GA VF ALE R + +L+AE + ++ EL+ L
Sbjct: 13 LVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGTALA 72
Query: 69 SEPHRA--------GVQWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPL 120
++ H G W + FA +++TT GYGH AP + GKAFCM YA LG+P
Sbjct: 73 TQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALGLPA 132
Query: 121 TLVMFQSLGERMNTFVRYLLKRIKKCCGMRNTDVSMENMVTVGFFSCMGTLCIGAAAFSQ 180
+L + +L + + + + ++ V +G + + A
Sbjct: 133 SLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVASSFVLLPALVLWG 192
Query: 181 CE-EWSFFHAYYYCFITLTTIGFGD 204
+ + S A Y+CF +L+TIG D
Sbjct: 193 LQGDCSLLGAVYFCFSSLSTIGLED 217
>gi|16118235 potassium channel, subfamily K, member 7 isoform B
[Homo sapiens]
Length = 252
Score = 75.1 bits (183), Expect = 1e-13
Identities = 56/205 (27%), Positives = 90/205 (43%), Gaps = 11/205 (5%)
Query: 11 LIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYRQLELV--ILQ 68
L+V L +GA VF ALE R + +L+AE + ++ EL+ L
Sbjct: 13 LVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGTALA 72
Query: 69 SEPHRA--------GVQWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPL 120
++ H G W + FA +++TT GYGH AP + GKAFCM YA LG+P
Sbjct: 73 TQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALGLPA 132
Query: 121 TLVMFQSLGERMNTFVRYLLKRIKKCCGMRNTDVSMENMVTVGFFSCMGTLCIGAAAFSQ 180
+L + +L + + + + ++ V +G + + A
Sbjct: 133 SLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVASSFVLLPALVLWG 192
Query: 181 CE-EWSFFHAYYYCFITLTTIGFGD 204
+ + S A Y+CF +L+TIG D
Sbjct: 193 LQGDCSLLGAVYFCFSSLSTIGLED 217
>gi|16118233 potassium channel, subfamily K, member 7 isoform B
[Homo sapiens]
Length = 252
Score = 75.1 bits (183), Expect = 1e-13
Identities = 56/205 (27%), Positives = 90/205 (43%), Gaps = 11/205 (5%)
Query: 11 LIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYRQLELV--ILQ 68
L+V L +GA VF ALE R + +L+AE + ++ EL+ L
Sbjct: 13 LVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGTALA 72
Query: 69 SEPHRA--------GVQWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPL 120
++ H G W + FA +++TT GYGH AP + GKAFCM YA LG+P
Sbjct: 73 TQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALGLPA 132
Query: 121 TLVMFQSLGERMNTFVRYLLKRIKKCCGMRNTDVSMENMVTVGFFSCMGTLCIGAAAFSQ 180
+L + +L + + + + ++ V +G + + A
Sbjct: 133 SLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVASSFVLLPALVLWG 192
Query: 181 CE-EWSFFHAYYYCFITLTTIGFGD 204
+ + S A Y+CF +L+TIG D
Sbjct: 193 LQGDCSLLGAVYFCFSSLSTIGLED 217
>gi|32469495 potassium channel, subfamily K, member 18 [Homo
sapiens]
Length = 384
Score = 71.6 bits (174), Expect = 1e-12
Identities = 47/137 (34%), Positives = 65/137 (47%), Gaps = 8/137 (5%)
Query: 17 TYLLVGAAVFDALESDHEM-----REEEKLKAEEIRIKGKYNISSEDYRQ-LELVILQSE 70
TY LVGA VF A+E + E EK E RI ED +Q L+ + + +
Sbjct: 32 TYALVGAVVFSAIEDGQVLVAADDGEFEKFLEELCRILNCSETVVEDRKQDLQGHLQKVK 91
Query: 71 PH--RAGVQWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPLTLVMFQSL 128
P W F S +F TV +T+GYG+ P T GK CM YA+ GIPL ++
Sbjct: 92 PQWFNRTTHWSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLCMLYALFGIPLMFLVLTDT 151
Query: 129 GERMNTFVRYLLKRIKK 145
G+ + T + R +K
Sbjct: 152 GDILATILSTSYNRFRK 168
Score = 47.0 bits (110), Expect = 3e-05
Identities = 24/62 (38%), Positives = 36/62 (58%), Gaps = 8/62 (12%)
Query: 186 FFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSFMYILVGLTVIGAFLNLVVLR 245
F +A+Y+CF+TLTTIGFGD V + P + F +YI+VG+ ++ LV R
Sbjct: 310 FENAFYFCFVTLTTIGFGDTVL--------EHPNFFLFFSIYIIVGMEIVFIAFKLVQNR 361
Query: 246 FL 247
+
Sbjct: 362 LI 363
Score = 33.1 bits (74), Expect = 0.42
Identities = 15/56 (26%), Positives = 26/56 (46%)
Query: 77 QWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPLTLVMFQSLGERM 132
Q F +FYF +TTIG+G F Y ++G+ + + F+ + R+
Sbjct: 307 QLDFENAFYFCFVTLTTIGFGDTVLEHPNFFLFFSIYIIVGMEIVFIAFKLVQNRL 362
Score = 32.3 bits (72), Expect = 0.71
Identities = 17/66 (25%), Positives = 31/66 (46%), Gaps = 1/66 (1%)
Query: 178 FSQCEEWSFFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSFMYILVGLTVIGA 237
F++ WSF + ++C +T+G+G Y+ T+ LY F + + LT G
Sbjct: 95 FNRTTHWSFLSSLFFCCTVFSTVGYG-YIYPVTRLGKYLCMLYALFGIPLMFLVLTDTGD 153
Query: 238 FLNLVV 243
L ++
Sbjct: 154 ILATIL 159
>gi|22024390 potassium voltage-gated channel, subfamily H, member 5
isoform 1 [Homo sapiens]
Length = 988
Score = 39.3 bits (90), Expect = 0.006
Identities = 18/46 (39%), Positives = 27/46 (58%)
Query: 80 FAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPLTLVMF 125
+ S YF +T +TTIG+G+ AP TD K F + ++G L +F
Sbjct: 419 YVSSLYFTMTSLTTIGFGNIAPTTDVEKMFSVAMMMVGSLLYATIF 464
>gi|27886648 potassium voltage-gated channel, subfamily H, member 5
isoform 2 [Homo sapiens]
Length = 624
Score = 39.3 bits (90), Expect = 0.006
Identities = 18/46 (39%), Positives = 27/46 (58%)
Query: 80 FAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPLTLVMF 125
+ S YF +T +TTIG+G+ AP TD K F + ++G L +F
Sbjct: 361 YVSSLYFTMTSLTTIGFGNIAPTTDVEKMFSVAMMMVGSLLYATIF 406
>gi|27886646 potassium voltage-gated channel, subfamily H, member 5
isoform 3 [Homo sapiens]
Length = 611
Score = 39.3 bits (90), Expect = 0.006
Identities = 18/46 (39%), Positives = 27/46 (58%)
Query: 80 FAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPLTLVMF 125
+ S YF +T +TTIG+G+ AP TD K F + ++G L +F
Sbjct: 419 YVSSLYFTMTSLTTIGFGNIAPTTDVEKMFSVAMMMVGSLLYATIF 464
>gi|4504831 potassium voltage-gated channel, subfamily H, member 1
isoform 2 [Homo sapiens]
Length = 962
Score = 38.1 bits (87), Expect = 0.013
Identities = 16/46 (34%), Positives = 27/46 (58%)
Query: 80 FAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPLTLVMF 125
+ S YF +T +T++G+G+ AP TD K F + ++G L +F
Sbjct: 423 YISSLYFTMTSLTSVGFGNIAPSTDIEKIFAVAIMMIGSLLYATIF 468
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.137 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,641,960
Number of Sequences: 37866
Number of extensions: 605116
Number of successful extensions: 2464
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 82
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 2216
Number of HSP's gapped (non-prelim): 185
length of query: 374
length of database: 18,247,518
effective HSP length: 104
effective length of query: 270
effective length of database: 14,309,454
effective search space: 3863552580
effective search space used: 3863552580
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.