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Search of human proteins with 14141161
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14141161 heterogeneous nuclear ribonucleoprotein U isoform b
[Homo sapiens]
(806 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14141161 heterogeneous nuclear ribonucleoprotein U isoform b ... 1664 0.0
gi|74136883 heterogeneous nuclear ribonucleoprotein U isoform a ... 1653 0.0
gi|21536326 heterogeneous nuclear ribonucleoprotein U-like 1 iso... 624 e-179
gi|118601081 heterogeneous nuclear ribonucleoprotein U-like 2 [H... 590 e-168
gi|21536320 heterogeneous nuclear ribonucleoprotein U-like 1 iso... 584 e-166
gi|4826686 DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 [Homo sapiens] 88 4e-17
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 83 1e-15
gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo sap... 74 7e-13
gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b... 70 6e-12
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma... 66 1e-10
gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isofor... 65 3e-10
gi|4504447 heterogeneous nuclear ribonucleoprotein A2/B1 isoform... 65 3e-10
gi|109452587 family with sequence similarity 98, member B isofor... 64 6e-10
gi|24415404 MDN1, midasin homolog [Homo sapiens] 59 1e-08
gi|12056465 fibrillarin [Homo sapiens] 59 2e-08
gi|4504445 heterogeneous nuclear ribonucleoprotein A1 isoform a ... 58 3e-08
gi|56699482 hypothetical protein LOC25940 [Homo sapiens] 56 1e-07
gi|21735415 centromere protein B [Homo sapiens] 56 2e-07
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 55 2e-07
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 55 2e-07
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 55 3e-07
gi|156151396 heterogeneous nuclear ribonucleoprotein R isoform 3... 55 3e-07
gi|156151394 heterogeneous nuclear ribonucleoprotein R isoform 1... 55 3e-07
gi|156151392 heterogeneous nuclear ribonucleoprotein R isoform 4... 55 3e-07
gi|5031755 heterogeneous nuclear ribonucleoprotein R isoform 2 [... 55 3e-07
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 55 3e-07
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 55 3e-07
gi|228008295 synaptotagmin binding, cytoplasmic RNA interacting ... 54 6e-07
gi|228008291 synaptotagmin binding, cytoplasmic RNA interacting ... 54 6e-07
gi|4504487 histidine rich calcium binding protein precursor [Hom... 54 6e-07
>gi|14141161 heterogeneous nuclear ribonucleoprotein U isoform b
[Homo sapiens]
Length = 806
Score = 1664 bits (4310), Expect = 0.0
Identities = 806/806 (100%), Positives = 806/806 (100%)
Query: 1 MSSSPVNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSL 60
MSSSPVNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSL
Sbjct: 1 MSSSPVNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSL 60
Query: 61 DLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGP 120
DLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGP
Sbjct: 61 DLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGP 120
Query: 121 MEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAA 180
MEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAA
Sbjct: 121 MEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAA 180
Query: 181 KEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGDGKTEQKGGDKKRGVKRPREDHGRGYFE 240
KEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGDGKTEQKGGDKKRGVKRPREDHGRGYFE
Sbjct: 181 KEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGDGKTEQKGGDKKRGVKRPREDHGRGYFE 240
Query: 241 YIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFKISRDRLSASSLTMESFAFL 300
YIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFKISRDRLSASSLTMESFAFL
Sbjct: 241 YIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFKISRDRLSASSLTMESFAFL 300
Query: 301 WAGGRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVRIGWSLTTSGMLLGEEEFSY 360
WAGGRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVRIGWSLTTSGMLLGEEEFSY
Sbjct: 301 WAGGRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVRIGWSLTTSGMLLGEEEFSY 360
Query: 361 GYSLKGIKTCNCETEDYGEKFDENDVITCFANFESDEVELSYAKNGQDLGVAFKISKEVL 420
GYSLKGIKTCNCETEDYGEKFDENDVITCFANFESDEVELSYAKNGQDLGVAFKISKEVL
Sbjct: 361 GYSLKGIKTCNCETEDYGEKFDENDVITCFANFESDEVELSYAKNGQDLGVAFKISKEVL 420
Query: 421 AGRPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVPLEDRVRGPKGPEEKKDCEV 480
AGRPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVPLEDRVRGPKGPEEKKDCEV
Sbjct: 421 AGRPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVPLEDRVRGPKGPEEKKDCEV 480
Query: 481 VMMIGLPGAGKTTWVTKHAAENPGKYNILGTNTIMDKMMVAGFKKQMADTGKLNTLLQRA 540
VMMIGLPGAGKTTWVTKHAAENPGKYNILGTNTIMDKMMVAGFKKQMADTGKLNTLLQRA
Sbjct: 481 VMMIGLPGAGKTTWVTKHAAENPGKYNILGTNTIMDKMMVAGFKKQMADTGKLNTLLQRA 540
Query: 541 PQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQRKAVVVCPKDEDYKQRTQK 600
PQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQRKAVVVCPKDEDYKQRTQK
Sbjct: 541 PQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQRKAVVVCPKDEDYKQRTQK 600
Query: 601 KAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKEEAQKLLEQYKEESKKALPP 660
KAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKEEAQKLLEQYKEESKKALPP
Sbjct: 601 KAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKEEAQKLLEQYKEESKKALPP 660
Query: 661 EKKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNFRGGAPGNRGGYNRRGNMPQR 720
EKKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNFRGGAPGNRGGYNRRGNMPQR
Sbjct: 661 EKKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNFRGGAPGNRGGYNRRGNMPQR 720
Query: 721 GGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRGNYNQNFRGRGNNRGYKNQS 780
GGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRGNYNQNFRGRGNNRGYKNQS
Sbjct: 721 GGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRGNYNQNFRGRGNNRGYKNQS 780
Query: 781 QGYNQWQQGQFWGQKPWSQHYHQGYY 806
QGYNQWQQGQFWGQKPWSQHYHQGYY
Sbjct: 781 QGYNQWQQGQFWGQKPWSQHYHQGYY 806
>gi|74136883 heterogeneous nuclear ribonucleoprotein U isoform a
[Homo sapiens]
Length = 825
Score = 1653 bits (4280), Expect = 0.0
Identities = 806/825 (97%), Positives = 806/825 (97%), Gaps = 19/825 (2%)
Query: 1 MSSSPVNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSL 60
MSSSPVNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSL
Sbjct: 1 MSSSPVNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSL 60
Query: 61 DLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGP 120
DLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGP
Sbjct: 61 DLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGP 120
Query: 121 MEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAA 180
MEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAA
Sbjct: 121 MEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAA 180
Query: 181 KEAAGKSSGPTSLFAVTVAPPGARQGQQQAGG-------------------DGKTEQKGG 221
KEAAGKSSGPTSLFAVTVAPPGARQGQQQAGG DGKTEQKGG
Sbjct: 181 KEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGKKKAEGGGGGGRPGAPAAGDGKTEQKGG 240
Query: 222 DKKRGVKRPREDHGRGYFEYIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFK 281
DKKRGVKRPREDHGRGYFEYIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFK
Sbjct: 241 DKKRGVKRPREDHGRGYFEYIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFK 300
Query: 282 ISRDRLSASSLTMESFAFLWAGGRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVR 341
ISRDRLSASSLTMESFAFLWAGGRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVR
Sbjct: 301 ISRDRLSASSLTMESFAFLWAGGRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVR 360
Query: 342 IGWSLTTSGMLLGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVITCFANFESDEVELS 401
IGWSLTTSGMLLGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVITCFANFESDEVELS
Sbjct: 361 IGWSLTTSGMLLGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVITCFANFESDEVELS 420
Query: 402 YAKNGQDLGVAFKISKEVLAGRPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVP 461
YAKNGQDLGVAFKISKEVLAGRPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVP
Sbjct: 421 YAKNGQDLGVAFKISKEVLAGRPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVP 480
Query: 462 LEDRVRGPKGPEEKKDCEVVMMIGLPGAGKTTWVTKHAAENPGKYNILGTNTIMDKMMVA 521
LEDRVRGPKGPEEKKDCEVVMMIGLPGAGKTTWVTKHAAENPGKYNILGTNTIMDKMMVA
Sbjct: 481 LEDRVRGPKGPEEKKDCEVVMMIGLPGAGKTTWVTKHAAENPGKYNILGTNTIMDKMMVA 540
Query: 522 GFKKQMADTGKLNTLLQRAPQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQ 581
GFKKQMADTGKLNTLLQRAPQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQ
Sbjct: 541 GFKKQMADTGKLNTLLQRAPQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQ 600
Query: 582 RKAVVVCPKDEDYKQRTQKKAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKE 641
RKAVVVCPKDEDYKQRTQKKAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKE
Sbjct: 601 RKAVVVCPKDEDYKQRTQKKAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKE 660
Query: 642 EAQKLLEQYKEESKKALPPEKKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNFR 701
EAQKLLEQYKEESKKALPPEKKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNFR
Sbjct: 661 EAQKLLEQYKEESKKALPPEKKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNFR 720
Query: 702 GGAPGNRGGYNRRGNMPQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRG 761
GGAPGNRGGYNRRGNMPQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRG
Sbjct: 721 GGAPGNRGGYNRRGNMPQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRG 780
Query: 762 NYNQNFRGRGNNRGYKNQSQGYNQWQQGQFWGQKPWSQHYHQGYY 806
NYNQNFRGRGNNRGYKNQSQGYNQWQQGQFWGQKPWSQHYHQGYY
Sbjct: 781 NYNQNFRGRGNNRGYKNQSQGYNQWQQGQFWGQKPWSQHYHQGYY 825
>gi|21536326 heterogeneous nuclear ribonucleoprotein U-like 1
isoform a [Homo sapiens]
Length = 856
Score = 624 bits (1610), Expect = e-179
Identities = 362/776 (46%), Positives = 471/776 (60%), Gaps = 96/776 (12%)
Query: 6 VNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSLDLGGD 65
++V++LKV+EL+EEL++R L +GLKAEL ERLQAAL+ EE ++ D
Sbjct: 1 MDVRRLKVNELREELQRRGLDTRGLKAELAERLQAALEAEEPDDERELD--------ADD 52
Query: 66 SAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGPMEEEE 125
GR G E+ GG E E + G+ E G +G G +
Sbjct: 53 EPGRPGHINEEVETEGGSELEGTAQPPPPGL-------QPHAEPGGYSG--PDGHYAMDN 103
Query: 126 AASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAAKEAAG 185
+++ D Q ++ E+E G E +P +QQQ + +
Sbjct: 104 ITRQNQFYDTQVIKQ-ENESGYER--------------RPLEMEQQQAYRPE---MKTEM 145
Query: 186 KSSGPTSLFAVTVAPPGARQGQQQAGGDGKTEQKGGDKKRGVKRPREDHGRGYFEYIEEN 245
K PTS PP A Q + Q+ +KR + E+ GRGYFE+ E+
Sbjct: 146 KQGAPTSFL-----PPEASQLKPD-------RQQFQSRKRPYE---ENRGRGYFEHREDR 190
Query: 246 KYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFKISRDRLSASSLTMESFAFLWAGGR 305
R +SPQPP EE+++ FDDT+V +DTYNCDLHFK++RDR S LT+E FA+LW+G R
Sbjct: 191 ---RGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFAYLWSGAR 247
Query: 306 ASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVRIGWSLTTSGMLLGEEEFSYGYSLK 365
ASYGV +G+VCFEMK+ E+I V+HL + + D H VRIGWSL + LGEE FSYGY
Sbjct: 248 ASYGVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSLDSCSTQLGEEPFSYGYGGT 307
Query: 366 GIKTCNCETEDYGEKFDENDVITCFANFE-SDEVELSYAKNGQDLGVAFKISKEVLAGRP 424
G K+ N E+YG+KF ENDVI CFA+FE ++VELS+ KNG+ +G+AF+I KE L G+
Sbjct: 308 GKKSTNSRFENYGDKFAENDVIGCFADFECGNDVELSFTKNGKWMGIAFRIQKEALGGQA 367
Query: 425 LFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVPLEDRVRGPKGPEEKKDCEVVMMI 484
L+PHVL NCAVEFNFGQ+ +PY + +TFIQ++PL +R+RG GP+ K +CE++MM+
Sbjct: 368 LYPHVLVKNCAVEFNFGQRAEPYCSVLPGFTFIQHLPLSERIRGTVGPKSKAECEILMMV 427
Query: 485 GLPGAGKTTWVTKHAAENPG-KYNILGTNTIMDKMMVAGFKKQMADTGKLNTLLQRAPQC 543
GLP AGKTTW KHAA NP KYNILGTN IMDKM V G ++Q G+ + L+Q+A QC
Sbjct: 428 GLPAAGKTTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLRRQRNYAGRWDVLIQQATQC 487
Query: 544 LGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQRKAVVVCPKDEDYKQRTQKKAE 603
L + I+IAARKKRN+ILDQTNV +AQRRKM F GFQRKA+V+CP DED K RT K+ +
Sbjct: 488 LNRLIQIAARKKRNYILDQTNVYGSAQRRKMRPFEGFQRKAIVICPTDEDLKDRTIKRTD 547
Query: 604 VEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKEEAQKLLEQYKEESKKALPPEKK 663
EGKD+P+HAVL+MK NFTLP+V + DE+ ++ELQ+EEA KL+ QY EE +KA PP +K
Sbjct: 548 EEGKDVPDHAVLEMKANFTLPDVGDFLDEVLFIELQREEADKLVRQYNEEGRKAGPPPEK 607
Query: 664 Q--NTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNF-----RGGAPGNRGGYNRRGN 716
+ N G GGG RGRGG GG F RG GNRGG+
Sbjct: 608 RFDNRG----------------GGGFRGRGG----GGGFQRYENRGPPGGNRGGFQ---- 643
Query: 717 MPQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRGNYNQNFRGRGN 772
RGGG GG G + R+ G G YS NR G NR N N N RG N
Sbjct: 644 --NRGGGSGGGGNYRGGFNRS----GGGGYSQ----NRWGNNNRDNNNSNNRGSYN 689
>gi|118601081 heterogeneous nuclear ribonucleoprotein U-like 2 [Homo
sapiens]
Length = 747
Score = 590 bits (1520), Expect = e-168
Identities = 330/723 (45%), Positives = 458/723 (63%), Gaps = 53/723 (7%)
Query: 6 VNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALD----DEEAGGRPAMEPGNGSLD 61
+ VK+LKV+EL+ EL++R L +GLK +L +RLQ ALD ++EAGG A PG G+
Sbjct: 1 MEVKRLKVTELRSELQRRGLDSRGLKVDLAQRLQEALDAEMLEDEAGGGGA-GPG-GACK 58
Query: 62 LGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGPM 121
SG G GGDEEE+EEEEEE+ + L+ + E AA P
Sbjct: 59 AEPRPVAASGGG------PGGDEEEDEEEEEEDEEALLEDEDEEPPPAQALGQAAQPPPE 112
Query: 122 EEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAAK 181
E AA E D + E G G+E G G+++ + +P+++ G
Sbjct: 113 PPEAAAMEAAAEPDASEKPAEATAGSGGVNGGEEQGLGKRE-------EDEPEERSG--D 163
Query: 182 EAAGKSSGPTSLFAVTVAPPGARQGQQQAGGDGKTEQK----GGD-KKRGVKRPRED--- 233
E G PG + ++Q GD + +K G D ++RGVKR R++
Sbjct: 164 ETPGSEV------------PGDKAAEEQ--GDDQDSEKSKPAGSDGERRGVKRQRDEKDE 209
Query: 234 HGRGYFEYIEENKYSRAKSPQPPVEE-EDEHFDDTVVCLDTYNCDLHFKISRDRLSASSL 292
HGR Y+E+ EE +SR+KSP PP EE +DE D T+V LDTY DLHF++S+DR L
Sbjct: 210 HGRAYYEFREEAYHSRSKSPLPPEEEAKDEEEDQTLVNLDTYTSDLHFQVSKDRYGGQPL 269
Query: 293 TMESFAFLWAGGRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVRIGWSLTTSGML 352
E F LW+G R++YGV+KGKVCFE KVT+ +P++ T ++ +R+GWS+ S
Sbjct: 270 FSEKFPTLWSGARSTYGVTKGKVCFEAKVTQNLPMKEGCT---EVSLLRVGWSVDFSRPQ 326
Query: 353 LGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVITCFANFESDEVELSYAKNGQDLGVA 412
LGE+EFSYG+ +G+K N + E++G+ F ENDVI CFANFE++EVELS++KNG+DLGVA
Sbjct: 327 LGEDEFSYGFDGRGLKAENGQFEEFGQTFGENDVIGCFANFETEEVELSFSKNGEDLGVA 386
Query: 413 FKISKEVLAGRPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVPLEDRVRGPKGP 472
F ISK+ LA R L PHVLC NC VE NFGQKE+P+FP PEE+ FI VP+E+RVR P
Sbjct: 387 FWISKDSLADRALLPHVLCKNCVVELNFGQKEEPFFPPPEEFVFIHAVPVEERVRTAVPP 446
Query: 473 EEKKDCEVVMMIGLPGAGKTTWVTKHAAENPGK-YNILGTNTIMDKMMVAGFKKQMADTG 531
+ ++CEV++M+GLPG+GKT W K+A ENP K YN+LG T++++M + G ++ D
Sbjct: 447 KTIEECEVILMVGLPGSGKTQWALKYAKENPEKRYNVLGAETVLNQMRMKGLEEPEMDPK 506
Query: 532 KLNTLLQRAPQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQRKAVVVCPKD 591
+ L+Q+A QCL K ++IA+R KRNFILDQ NV + QRRK+ LF F RK VVV P +
Sbjct: 507 SRDLLVQQASQCLSKLVQIASRTKRNFILDQCNVYNSGQRRKLLLFKTFSRKVVVVVPNE 566
Query: 592 EDYKQRTQKKAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKEEAQKLLEQYK 651
ED+K+R + + EVEG D+PE +L+MK NF+LPE + DE+TY EL+KEEAQ ++ +YK
Sbjct: 567 EDWKKRLELRKEVEGDDVPESIMLEMKANFSLPEKCDYMDEVTYGELEKEEAQPIVTKYK 626
Query: 652 EESKKALPPEKKQNTGSKKSNKNKSGKNQFNRGGGHRG---RGGFNMRGGNFRGGAPGNR 708
EE++K LPP +K+ ++++N+NK + +RG G+ G RG N G G PGNR
Sbjct: 627 EEARKLLPPSEKRT--NRRNNRNKRNRQNRSRGQGYVGGQRRGYDNRAYGQQYWGQPGNR 684
Query: 709 GGY 711
GGY
Sbjct: 685 GGY 687
>gi|21536320 heterogeneous nuclear ribonucleoprotein U-like 1
isoform d [Homo sapiens]
Length = 756
Score = 584 bits (1505), Expect = e-166
Identities = 304/555 (54%), Positives = 383/555 (69%), Gaps = 47/555 (8%)
Query: 228 KRPREDH-GRGYFEYIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFKISRDR 286
KRP E++ GRGYFE+ E+ R +SPQPP EE+++ FDDT+V +DTYNCDLHFK++RDR
Sbjct: 72 KRPYEENRGRGYFEHREDR---RGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDR 128
Query: 287 LSASSLTMESFAFLWAGGRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVRIGWSL 346
S LT+E FA+LW+G RASYGV +G+VCFEMK+ E+I V+HL + + D H VRIGWSL
Sbjct: 129 SSGYPLTIEGFAYLWSGARASYGVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSL 188
Query: 347 TTSGMLLGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVITCFANFE-SDEVELSYAKN 405
+ LGEE FSYGY G K+ N E+YG+KF ENDVI CFA+FE ++VELS+ KN
Sbjct: 189 DSCSTQLGEEPFSYGYGGTGKKSTNSRFENYGDKFAENDVIGCFADFECGNDVELSFTKN 248
Query: 406 GQDLGVAFKISKEVLAGRPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVPLEDR 465
G+ +G+AF+I KE L G+ L+PHVL NCAVEFNFGQ+ +PY + +TFIQ++PL +R
Sbjct: 249 GKWMGIAFRIQKEALGGQALYPHVLVKNCAVEFNFGQRAEPYCSVLPGFTFIQHLPLSER 308
Query: 466 VRGPKGPEEKKDCEVVMMIGLPGAGKTTWVTKHAAENPGK-YNILGTNTIMDKMMVAGFK 524
+RG GP+ K +CE++MM+GLP AGKTTW KHAA NP K YNILGTN IMDKM V G +
Sbjct: 309 IRGTVGPKSKAECEILMMVGLPAAGKTTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLR 368
Query: 525 KQMADTGKLNTLLQRAPQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQRKA 584
+Q G+ + L+Q+A QCL + I+IAARKKRN+ILDQTNV +AQRRKM F GFQRKA
Sbjct: 369 RQRNYAGRWDVLIQQATQCLNRLIQIAARKKRNYILDQTNVYGSAQRRKMRPFEGFQRKA 428
Query: 585 VVVCPKDEDYKQRTQKKAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKEEAQ 644
+V+CP DED K RT K+ + EGKD+P+HAVL+MK NFTLP+V + DE+ ++ELQ+EEA
Sbjct: 429 IVICPTDEDLKDRTIKRTDEEGKDVPDHAVLEMKANFTLPDVGDFLDEVLFIELQREEAD 488
Query: 645 KLLEQYKEESKKALPPEKKQ--NTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNF-- 700
KL+ QY EE +KA PP +K+ N G GGG RGRGG GG F
Sbjct: 489 KLVRQYNEEGRKAGPPPEKRFDNRG----------------GGGFRGRGG----GGGFQR 528
Query: 701 ---RGGAPGNRGGYNRRGNMPQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGM 757
RG GNRGG+ RGGG GG G + R+ G G YS NR G
Sbjct: 529 YENRGPPGGNRGGFQ------NRGGGSGGGGNYRGGFNRS----GGGGYSQ----NRWGN 574
Query: 758 PNRGNYNQNFRGRGN 772
NR N N N RG N
Sbjct: 575 NNRDNNNSNNRGSYN 589
>gi|4826686 DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 [Homo sapiens]
Length = 740
Score = 87.8 bits (216), Expect = 4e-17
Identities = 57/194 (29%), Positives = 99/194 (51%), Gaps = 27/194 (13%)
Query: 271 LDTYNCDLHFKISRDRLSASSLTMESFAFLWAGGRASYGVSKGKVCFEMKVTEKIPVRHL 330
++ Y+ F I D L S ++ W G RA+ G+ KGK H
Sbjct: 93 MNPYDRGSAFAIGSDGLCCQSREVKE----WHGCRATKGLMKGK--------------HY 134
Query: 331 YTKDIDIHE---VRIGWSLTTSGMLLGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVI 387
Y ++ H+ R+GWS + + LG ++F +G+ G K+ N + ++YGE+F +D I
Sbjct: 135 Y--EVSCHDQGLCRVGWSTMQASLDLGTDKFGFGFGGTGKKSHNKQFDNYGEEFTMHDTI 192
Query: 388 TCFANFESDEVELSYAKNGQDLGVAFKISKEVLAGRPLFPHVLCHNCAVEFNFGQKEKPY 447
C+ + + V+ ++KNG+DLG+AF+I + + LFP + N ++FNFG++E
Sbjct: 193 GCYLDIDKGHVK--FSKNGKDLGLAFEIPPH-MKNQALFPACVLKNAELKFNFGEEEFK- 248
Query: 448 FPIPEEYTFIQNVP 461
FP + + + P
Sbjct: 249 FPPKDGFVALSKAP 262
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 82.8 bits (203), Expect = 1e-15
Identities = 75/254 (29%), Positives = 116/254 (45%), Gaps = 10/254 (3%)
Query: 19 ELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSLDLGGDSAGRSGAGLEQEA 78
E KK + K K E E Q ++EE GR + G ++ GG+ G E+E
Sbjct: 774 ERKKEERAGKEEKGE-EEGDQGEGEEEETEGRGEEKEEGGEVE-GGEVEEGKGEREEEEE 831
Query: 79 AAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGPMEEEEAASEDENGDDQGF 138
G+EEE E EEEE +G+ GEE G G + EE E E+E G+ +G
Sbjct: 832 EGEGEEEEGEGEEEEGEGEEEEGEGK--GEEEGEEGEGEE-EGEEGEGEGEEEEGEGEGE 888
Query: 139 QEGEDELGDEE-EGAGDENGHGE-QQPQPPATQQQQPQQQRGAAKEAAGKSSGPTSLFAV 196
+EGE E +EE EG G+E G GE ++ + +++ ++ G +E G+ G
Sbjct: 889 EEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDG-EGE 947
Query: 197 TVAPPGARQGQQQAG-GDGKTEQKG-GDKKRGVKRPREDHGRGYFEYIEENKYSRAKSPQ 254
G +G+++ G G+G+ E +G G++ G E G G E EE + +
Sbjct: 948 GEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEE 1007
Query: 255 PPVEEEDEHFDDTV 268
E +E + V
Sbjct: 1008 EGEGEGEEEEEGEV 1021
Score = 80.5 bits (197), Expect = 6e-15
Identities = 70/243 (28%), Positives = 108/243 (44%), Gaps = 38/243 (15%)
Query: 43 DDEEAGGRPAMEPGNGSLDLGGDSAGRSGAGLEQEAAAGGDEEEEEE---EEEEEGISAL 99
+ EE G E G + + AG+ G E+E G EEEE E EE+EEG +
Sbjct: 760 EGEEVEGEREKEEGERKKE---ERAGKEEKG-EEEGDQGEGEEEETEGRGEEKEEG-GEV 814
Query: 100 DGDQMELG------EENGAAGAADSGPMEEEEAASEDENGDDQGFQEGEDELGDEE---- 149
+G ++E G EE G + G EEEE E+E G+ +G +EGE+ G+EE
Sbjct: 815 EGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEG 874
Query: 150 ---------EGAGDENGHGEQQPQPPATQQQQPQQQRGAAKEAAGKSSGPTSLFAVTVAP 200
EG G+E G GE + + + ++ + G +E GK
Sbjct: 875 EGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGE--------EEGE 926
Query: 201 PGARQGQQQAG-GDGKTEQKGGDKKRGVKRPREDHGRGYFEYIEENKYSRAKSPQPPVEE 259
G +G+++ G G+G+ + G+++ G E+ G G E EE + + EE
Sbjct: 927 EGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGE--EEGEGEGEEGEGEGEEE 984
Query: 260 EDE 262
E E
Sbjct: 985 EGE 987
Score = 75.1 bits (183), Expect = 2e-13
Identities = 74/256 (28%), Positives = 111/256 (43%), Gaps = 25/256 (9%)
Query: 17 KEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSLDLGGDSAGRSGAGLEQ 76
+EE + +G E E + + EE G E G G + G+ G G +
Sbjct: 844 EEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGE 903
Query: 77 EAAAGGDEEEEEEEE---EEEGISALDGDQMELGEENGAAGAADSGPMEEEEAASEDENG 133
G E EEEE E EEEG + E GE G G + G EE E E+E G
Sbjct: 904 GEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGE-GEEEEGEWEGEEEEG 962
Query: 134 DDQGFQEGEDELGDEEEGAGDE---NGHGEQQPQPPATQQQQPQQQRGAAKEAAGKSSGP 190
+ +G +EGE E G+E EG G+E G GE++ +++ ++ G E G+
Sbjct: 963 EGEGEEEGEGE-GEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEG---EGEGEEEEE 1018
Query: 191 TSLFAVTVAPPGARQGQQQAG-GDGKTEQKGGDKKRGVKRPREDHGRGYFEYIEENKYSR 249
+ G +G+++ G +G+ +K G+ + +R RE+ E EE KY
Sbjct: 1019 GEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEEN-RRNREE------EEEEEGKY-- 1069
Query: 250 AKSPQPPVEEEDEHFD 265
Q EEE+E D
Sbjct: 1070 ----QETGEEENERQD 1081
Score = 64.7 bits (156), Expect = 3e-10
Identities = 65/254 (25%), Positives = 106/254 (41%), Gaps = 40/254 (15%)
Query: 45 EEAGGRPAME-PGNGSLDLGGDSAGRSGAGLEQEAAA---------------GGDEE--- 85
E+ GR ME PG G +L + G EQE GG+EE
Sbjct: 678 EKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGE 737
Query: 86 --EEEEEEEEEGISALDGDQMELGEENGAAGAADSGPMEEEEAASEDENGDDQGFQ-EGE 142
EEE + EEE +G + GEE + G ++EE A ++E G+++G Q EGE
Sbjct: 738 GEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGE 797
Query: 143 DE----LGDEEEGAGD------ENGHGEQQPQPP----ATQQQQPQQQRGAAKEAAGKSS 188
+E G+E+E G+ E G GE++ + ++ + +++ G +E G+
Sbjct: 798 EEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGK 857
Query: 189 GPTSLFAVTVAPPGARQGQQQAGGDGKTEQKGGDKKRGVKRPREDHGRGYFEYIEENKYS 248
G G +G++ G + E +G ++ G E+ G G E E +
Sbjct: 858 GEEE----GEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGE 913
Query: 249 RAKSPQPPVEEEDE 262
+ EE +E
Sbjct: 914 EEEGEGKGEEEGEE 927
Score = 62.0 bits (149), Expect = 2e-09
Identities = 44/149 (29%), Positives = 69/149 (46%), Gaps = 6/149 (4%)
Query: 43 DDEEAGGRPAMEPGNGSLDLGGDSAGRSGAGL--EQEAAAGGDEEEEEEEEEEEGISALD 100
++EE E G G + G+ G G G E+E G+EEE EEE EEEG +
Sbjct: 949 EEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEE 1008
Query: 101 GDQMELGEENGAAGAADSGPMEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGE 160
G+ EE G G EE E E+E G+++G E ++ G+ EE + E
Sbjct: 1009 GEGEGEEEEEGEVEGEVEG--EEGEGEGEEEEGEEEG--EEREKEGEGEENRRNREEEEE 1064
Query: 161 QQPQPPATQQQQPQQQRGAAKEAAGKSSG 189
++ + T +++ ++Q G + K G
Sbjct: 1065 EEGKYQETGEEENERQDGEEYKKVSKIKG 1093
Score = 45.1 bits (105), Expect = 3e-04
Identities = 56/267 (20%), Positives = 105/267 (39%), Gaps = 32/267 (11%)
Query: 12 KVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSLDLGGDSAGRSG 71
++SE+KE ++ +G+ A DEE E G+ D G+
Sbjct: 549 EMSEMKEGKACKQHVSQGIFMTQPATTIEAFSDEEV---EIPEEKEGAEDSKGNGIEEQE 605
Query: 72 AGLEQEAAA--GGDEEEEE--EEEEEEGISALDGDQMELGE-------------ENGAAG 114
+E GG +E+ E ++ + +G +GE E G++G
Sbjct: 606 VEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSG 665
Query: 115 AADSGPMEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQ 174
A E E+ + G+ + EGE EL ++EE + EQ+ + Q+++ Q
Sbjct: 666 AEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQ 725
Query: 175 QQRGAAKEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGDGKTEQKGGDKKRGVKRPREDH 234
+ +E G+ G R+ +++ G+GK E +G + + +R +E+
Sbjct: 726 EMEEGGEEEHGEGE----------EEEGDREEEEEKEGEGKEEGEGEEVEG--EREKEEG 773
Query: 235 GRGYFEYIEENKYSRAKSPQPPVEEED 261
R E + + + Q EEE+
Sbjct: 774 ERKKEERAGKEEKGEEEGDQGEGEEEE 800
Score = 39.7 bits (91), Expect = 0.011
Identities = 39/146 (26%), Positives = 55/146 (37%), Gaps = 19/146 (13%)
Query: 43 DDEEAGGRPAMEPGN--GSLDLGGDSAGRSGAGLEQEAAAGGDEEEEE---EEEEEEGIS 97
++EE G E G G + G+ G E+E G+ E EE E EEEEG
Sbjct: 982 EEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEG-- 1039
Query: 98 ALDGDQMELGEENGAAGAADSGPMEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENG 157
E GEE G + EE E+ + G +E E + G+E + G
Sbjct: 1040 ------EEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKG 1093
Query: 158 ------HGEQQPQPPATQQQQPQQQR 177
H Q + Q ++QR
Sbjct: 1094 SVKYGKHKTYQKKSVTNTQGNGKEQR 1119
Score = 32.3 bits (72), Expect = 1.8
Identities = 35/169 (20%), Positives = 62/169 (36%), Gaps = 19/169 (11%)
Query: 639 QKEEAQKLLEQYKEESKKALPPEKKQNTGSKK----SNKNKSGKNQFNRGGGHR----GR 690
++EE +K E +E + + E+++ G +K + K + G+ + ++G G GR
Sbjct: 745 REEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGR 804
Query: 691 GGFNMRGGNFRGG----APGNRGGYNRRGNMPQRGGGGGGSGGIGYPYPRAPVFPGRGSY 746
G GG GG G R G + G G G G G G
Sbjct: 805 GEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEE------EGEGKG 858
Query: 747 SNRGNYNRGGMPNRGNYNQNFRGRGNNRGYKNQSQGYNQWQQGQFWGQK 795
G G + G G + + +G + ++G+ G++
Sbjct: 859 EEEGEEGEGEEEGEEGEGEGEEEEGEGEG-EEEGEGEGEEEEGEGEGEE 906
>gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo
sapiens]
Length = 378
Score = 73.6 bits (179), Expect = 7e-13
Identities = 62/195 (31%), Positives = 77/195 (39%), Gaps = 23/195 (11%)
Query: 630 FDEITYVELQKEEAQKLLEQYKEESKKALPPEKKQNTGSKKSNKNKSGKNQFNRGGGHRG 689
FD+ V+ + + + E KKAL ++ Q+ GS++ SG N RGG G
Sbjct: 174 FDDHDTVDKIVVQKYHTINGHNCEVKKALSKQEMQSAGSQRGRGGGSG-NFMGRGGNFGG 232
Query: 690 RGGFNMRGGNFRGGAPGNRGGYNRRGNMPQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNR 749
GG RGGNF G GG RG+ GG G GG G Y P + RG Y
Sbjct: 233 GGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDGGYNGFGGDGGNYGGGPGYSSRGGYGGG 292
Query: 750 G-----------------NYNRGGMPNRGNY--NQNFRGRGNNRGYKNQSQGYNQWQQGQ 790
G YN GG GNY N+ GN G Q Y + G
Sbjct: 293 GPGYGNQGGGYGGGGGYDGYNEGGNFGGGNYGGGGNYNDFGNYSG--QQQSNYGPMKGGS 350
Query: 791 FWGQKPWSQHYHQGY 805
F G+ S Y GY
Sbjct: 351 FGGRSSGSP-YGGGY 364
Score = 44.7 bits (104), Expect = 4e-04
Identities = 31/91 (34%), Positives = 37/91 (40%), Gaps = 27/91 (29%)
Query: 668 SKKSNKNKSGKNQFNRGGGHRGRGGFN--MRGGNFRGGAPGNRGGYNRRGNM-------- 717
S + G N+GGG+ G GG++ GGNF GG G G YN GN
Sbjct: 284 SSRGGYGGGGPGYGNQGGGYGGGGGYDGYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNY 343
Query: 718 -PQRGGG----------------GGGSGGIG 731
P +GG GGGSGG G
Sbjct: 344 GPMKGGSFGGRSSGSPYGGGYGSGGGSGGYG 374
Score = 33.5 bits (75), Expect = 0.81
Identities = 35/137 (25%), Positives = 47/137 (34%), Gaps = 15/137 (10%)
Query: 56 GNGSLDLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAA-- 113
G G+ GG+ GR G G GG + G + GD G G +
Sbjct: 233 GGGNFGRGGNFGGRGGYG------GGGGGSRGSYGGGDGGYNGFGGDGGNYGGGPGYSSR 286
Query: 114 -GAADSGPMEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQ 172
G GP + G G+ EG + G G G+ N G Q QQ
Sbjct: 287 GGYGGGGPGYGNQGGGYGGGGGYDGYNEGGNFGGGNYGGGGNYNDFGNYSGQ----QQSN 342
Query: 173 PQQQRGAAKEAAGKSSG 189
+G + G+SSG
Sbjct: 343 YGPMKGGS--FGGRSSG 357
>gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b
[Homo sapiens]
Length = 372
Score = 70.5 bits (171), Expect = 6e-12
Identities = 58/165 (35%), Positives = 73/165 (44%), Gaps = 27/165 (16%)
Query: 653 ESKKALPPEKKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNF--RGGAPGNRG- 709
E +KAL ++ + S + ++ SG RGGG G F RGGNF RGG G+RG
Sbjct: 176 EVRKALSKQEMASASSSQRGRSGSGNFGGGRGGGFGGNDNFG-RGGNFSGRGGFGGSRGG 234
Query: 710 --------GYNRRGNMPQRGGGGG---------GSGGIGYPYPRAPVFPGRGSYSNRGNY 752
GYN GN GGGG GSGG GY + + G GSY + N
Sbjct: 235 GGYGGSGDGYNGFGNDGGYGGGGPGYSGGSRGYGSGGQGYG-NQGSGYGGSGSYDSYNNG 293
Query: 753 NRGGMPNRGNYNQNFRGRGNNR---GYKNQSQGYNQWQQGQFWGQ 794
GG G NF G G+ Y NQS + + G F G+
Sbjct: 294 GGGGF--GGGSGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGR 336
Score = 36.6 bits (83), Expect = 0.095
Identities = 25/71 (35%), Positives = 31/71 (43%), Gaps = 9/71 (12%)
Query: 665 NTGSKKSNKNKSGKNQFNRGGGHRGRGGFN--------MRGGNFRGGAPGNRGGYNRRGN 716
N G SG N F GG + G +N M+GGNF G + G GG +
Sbjct: 291 NNGGGGGFGGGSGSN-FGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFA 349
Query: 717 MPQRGGGGGGS 727
P+ GG GGS
Sbjct: 350 KPRNQGGYGGS 360
Score = 34.7 bits (78), Expect = 0.36
Identities = 33/102 (32%), Positives = 43/102 (42%), Gaps = 14/102 (13%)
Query: 664 QNTGSKKSNKNKSGK--NQFNRGGGHRGRGGFNMRGGNFRGGAPGNR-GGYNRRGNM--P 718
Q G++ S SG + N GGG G G G NF GG N G YN + + P
Sbjct: 272 QGYGNQGSGYGGSGSYDSYNNGGGGGFGGGS----GSNFGGGGSYNDFGNYNNQSSNFGP 327
Query: 719 QRGGGGGGS-----GGIGYPYPRAPVFPGRGSYSNRGNYNRG 755
+GG GG GG G + + G G S+ +Y G
Sbjct: 328 MKGGNFGGRSSGPYGGGGQYFAKPRNQGGYGGSSSSSSYGSG 369
>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
[Homo sapiens]
Length = 526
Score = 65.9 bits (159), Expect = 1e-10
Identities = 62/223 (27%), Positives = 89/223 (39%), Gaps = 44/223 (19%)
Query: 596 QRTQKKAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKEEAQKLLEQYKEESK 655
Q ++ +E + D V + N T+ VA+ F +I ++ K+ Q ++ Y +
Sbjct: 271 QGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRET 330
Query: 656 KAL----------PP---------EKKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMR 696
L PP + K+ +G+ + + FNRGGG+ GRGG
Sbjct: 331 GKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGN-GRGGRGRG 389
Query: 697 GGNFRGGAPGNRGGYNRRGNMPQRGGGGGG---SGGIGYPYPRA---------------- 737
G RGG G G RG P GGGGGG +G P P
Sbjct: 390 GPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKA 449
Query: 738 --PVFPGRGSYSNR--GNYNRGGMPNRGNYNQ-NFRGRGNNRG 775
P PG G + GNY RG Y++ +RGRG +RG
Sbjct: 450 PKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRG 492
Score = 51.2 bits (121), Expect = 4e-06
Identities = 39/109 (35%), Positives = 52/109 (47%), Gaps = 21/109 (19%)
Query: 677 GKNQFNRGGGHRGRGGFNMRGGNFRGGAPGNRGGYNRRGNMPQRGGGGGGSGGIGYPYPR 736
G Q +RGG RGRGG GG GG + GGY RG RGGG GG GG+G
Sbjct: 207 GYGQQDRGG--RGRGGSGGGGGGGGGGYNRSSGGYEPRG----RGGGRGGRGGMG----- 255
Query: 737 APVFPGRGSYSNRGNYNR-GGMPNRGNYNQNFRGRGNNRGYKNQSQGYN 784
S+RG +N+ GG ++G+ + + + +N Q G N
Sbjct: 256 ---------GSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGEN 295
Score = 50.8 bits (120), Expect = 5e-06
Identities = 43/140 (30%), Positives = 56/140 (40%), Gaps = 15/140 (10%)
Query: 662 KKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNF------RGGAPGNRGGYNRRG 715
++Q+ G ++S G Q N+ G GG GGN+ G+ GGY G
Sbjct: 139 QQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGY---G 195
Query: 716 NMPQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRGNYNQNFRGRGNNRG 775
N Q GGGG G G R G G G YNR G Y RGRG RG
Sbjct: 196 NQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSS----GGYEP--RGRGGGRG 249
Query: 776 YKNQSQGYNQWQQGQFWGQK 795
+ G ++ +F G +
Sbjct: 250 GRGGMGGSDRGGFNKFGGPR 269
Score = 50.4 bits (119), Expect = 6e-06
Identities = 39/131 (29%), Positives = 57/131 (43%), Gaps = 12/131 (9%)
Query: 664 QNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNFRGGAPGNR--------GGYNR-- 713
Q G + + SG GGG+ G+ +M G GG GN+ GGY +
Sbjct: 153 QGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQD 212
Query: 714 RGNMPQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRGNYNQNFRGRGNN 773
RG + G GGGG GG G + + RG RG G +RG +N+ G +
Sbjct: 213 RGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNK--FGGPRD 270
Query: 774 RGYKNQSQGYN 784
+G ++ S+ N
Sbjct: 271 QGSRHDSEQDN 281
Score = 47.0 bits (110), Expect = 7e-05
Identities = 37/108 (34%), Positives = 48/108 (44%), Gaps = 27/108 (25%)
Query: 672 NKNKSGKNQFNR------GGGHRGRGGFNMRGGNFRGGAPGNRGGYNR---RGNMPQRGG 722
N N S +N+ N+ G G GG +M GGN+ G RGGY+R RG RGG
Sbjct: 435 NMNFSWRNECNQCKAPKPDGPGGGPGGSHM-GGNYGDDRRGGRGGYDRGGYRGRGGDRGG 493
Query: 723 GGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRGNYNQNFRGR 770
GG GG +RG + G M +RG + Q+ R R
Sbjct: 494 FRGGRGG-----------------GDRGGFGPGKMDSRGEHRQDRRER 524
Score = 46.6 bits (109), Expect = 9e-05
Identities = 40/143 (27%), Positives = 51/143 (35%), Gaps = 14/143 (9%)
Query: 660 PEKKQNTGSKKSNKNKSGKNQFNRGGGHR--GRGGFNMRGGNFRGGAPGNRGGYNRRGNM 717
P +GS S+ S Q G + GG G + P G + N
Sbjct: 104 PAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNS 163
Query: 718 PQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRGNYNQNFR--------- 768
GGGGGG GG Y ++ + G GS GN ++ G G Y Q R
Sbjct: 164 SS-GGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSG 222
Query: 769 --GRGNNRGYKNQSQGYNQWQQG 789
G G GY S GY +G
Sbjct: 223 GGGGGGGGGYNRSSGGYEPRGRG 245
Score = 38.9 bits (89), Expect = 0.019
Identities = 40/191 (20%), Positives = 72/191 (37%), Gaps = 19/191 (9%)
Query: 48 GGRPAMEPGNGSLDLGGDSA--GRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQME 105
G +PA +GS S+ G+ +G + + G +++ +++ G Q +
Sbjct: 101 GQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQ 160
Query: 106 LGEENGAAGAADSGPMEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQP 165
+G G G ++ +S G G +D+ G G G+G
Sbjct: 161 YNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQ-----SGGGGSGGYG------ 209
Query: 166 PATQQQQPQQQRGAAKEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGDGKTEQKGGDKKR 225
QQ + + RG + G G + + P G G+ GG G +++ G +K
Sbjct: 210 ---QQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFG 266
Query: 226 GVKRPREDHGR 236
G PR+ R
Sbjct: 267 G---PRDQGSR 274
>gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isoform
B1 [Homo sapiens]
Length = 353
Score = 65.1 bits (157), Expect = 3e-10
Identities = 56/183 (30%), Positives = 72/183 (39%), Gaps = 17/183 (9%)
Query: 631 DEITYVELQKEEAQKLLEQYKEESKKALPPEKKQNTGSKKSNKNKS-GKNQFNRGGGHRG 689
D + + LQK + + E +KAL ++ Q S +S + + G GGG+ G
Sbjct: 164 DPVDKIVLQKYHT---INGHNAEVRKALSRQEMQEVQSSRSGRGGNFGFGDSRGGGGNFG 220
Query: 690 RGGFNMRGGNFRGGAPG---NRG---GYNRRGNMPQRGGGGGGSGGIGYPYPRAPVFPGR 743
G G NFRGG+ G RG GYN G P GGG G GY R G
Sbjct: 221 PGP----GSNFRGGSDGYGSGRGFGDGYNGYGGGP---GGGNFGGSPGYGGGRGGYGGGG 273
Query: 744 GSYSNRGNYNRGGMPNRGNYNQNFRGRGNNRGYKNQSQGYNQWQQGQFWGQKPWSQHYHQ 803
Y N+G GG N G N + Y Q Y + G F G + Y
Sbjct: 274 PGYGNQGGGYGGGYDNYGGGNYGSGNYNDFGNYNQQPSNYGPMKSGNFGGSRNMGGPYGG 333
Query: 804 GYY 806
G Y
Sbjct: 334 GNY 336
Score = 47.8 bits (112), Expect = 4e-05
Identities = 32/99 (32%), Positives = 44/99 (44%), Gaps = 10/99 (10%)
Query: 667 GSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNFRGGAPGNRGGYNRRGNM--PQRGGGG 724
G + G N+GGG+ G G N GGN+ G + G YN++ + P + G
Sbjct: 263 GGGRGGYGGGGPGYGNQGGGYGG-GYDNYGGGNYGSGNYNDFGNYNQQPSNYGPMKSGNF 321
Query: 725 GGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRGNY 763
GGS +G PY G G+Y G+ GG R Y
Sbjct: 322 GGSRNMGGPY-------GGGNYGPGGSGGSGGYGGRSRY 353
>gi|4504447 heterogeneous nuclear ribonucleoprotein A2/B1 isoform A2
[Homo sapiens]
Length = 341
Score = 65.1 bits (157), Expect = 3e-10
Identities = 56/183 (30%), Positives = 72/183 (39%), Gaps = 17/183 (9%)
Query: 631 DEITYVELQKEEAQKLLEQYKEESKKALPPEKKQNTGSKKSNKNKS-GKNQFNRGGGHRG 689
D + + LQK + + E +KAL ++ Q S +S + + G GGG+ G
Sbjct: 152 DPVDKIVLQKYHT---INGHNAEVRKALSRQEMQEVQSSRSGRGGNFGFGDSRGGGGNFG 208
Query: 690 RGGFNMRGGNFRGGAPG---NRG---GYNRRGNMPQRGGGGGGSGGIGYPYPRAPVFPGR 743
G G NFRGG+ G RG GYN G P GGG G GY R G
Sbjct: 209 PGP----GSNFRGGSDGYGSGRGFGDGYNGYGGGP---GGGNFGGSPGYGGGRGGYGGGG 261
Query: 744 GSYSNRGNYNRGGMPNRGNYNQNFRGRGNNRGYKNQSQGYNQWQQGQFWGQKPWSQHYHQ 803
Y N+G GG N G N + Y Q Y + G F G + Y
Sbjct: 262 PGYGNQGGGYGGGYDNYGGGNYGSGNYNDFGNYNQQPSNYGPMKSGNFGGSRNMGGPYGG 321
Query: 804 GYY 806
G Y
Sbjct: 322 GNY 324
Score = 47.8 bits (112), Expect = 4e-05
Identities = 32/99 (32%), Positives = 44/99 (44%), Gaps = 10/99 (10%)
Query: 667 GSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNFRGGAPGNRGGYNRRGNM--PQRGGGG 724
G + G N+GGG+ G G N GGN+ G + G YN++ + P + G
Sbjct: 251 GGGRGGYGGGGPGYGNQGGGYGG-GYDNYGGGNYGSGNYNDFGNYNQQPSNYGPMKSGNF 309
Query: 725 GGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRGNY 763
GGS +G PY G G+Y G+ GG R Y
Sbjct: 310 GGSRNMGGPY-------GGGNYGPGGSGGSGGYGGRSRY 341
>gi|109452587 family with sequence similarity 98, member B isoform 1
[Homo sapiens]
Length = 433
Score = 63.9 bits (154), Expect = 6e-10
Identities = 43/104 (41%), Positives = 47/104 (45%), Gaps = 3/104 (2%)
Query: 684 GGGHRGRGGFNMRGGNFRGGAPGNRGGYNRRGNMPQRGGGGGGSGGIGYPYPRAPVFPGR 743
GGG G GG GG GG G RGG+ G GGGGGG G G R F GR
Sbjct: 332 GGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGG-FQGR 390
Query: 744 GSYSNRGNY-NRGGMPNRGNYNQNFRGRGNNRGYKNQSQGYNQW 786
G Y RG Y RGG RG Y + G G G GY ++
Sbjct: 391 GDYGGRGGYGGRGGYGGRG-YGDPYGGGGGGGGGGGGGGGYRRY 433
>gi|24415404 MDN1, midasin homolog [Homo sapiens]
Length = 5596
Score = 59.3 bits (142), Expect = 1e-08
Identities = 58/227 (25%), Positives = 96/227 (42%), Gaps = 40/227 (17%)
Query: 7 NVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAG--------GRPAMEPGNG 58
N K K + K+E K+ +D G + E +++ +D+ + G P
Sbjct: 4820 NSNKDKSQQDKKEEKEEAEADDGGQGE--DKINEQIDERDYDENEVDPYHGNQEKVPEPE 4877
Query: 59 SLDLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADS 118
+LDL D L+ E GG E+ + EE EEE + E G E G ++
Sbjct: 4878 ALDLPDD------LNLDSEDKNGG-EDTDNEEGEEENPLEIKEKPEEAGHEAEERGETET 4930
Query: 119 ------GPMEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQ 172
P E EE SED+ EGE+E+ + GA D++G Q P+ + +QQQ
Sbjct: 4931 DQNESQSPQEPEEGPSEDDKA------EGEEEM---DTGADDQDGDAAQHPEEHSEEQQQ 4981
Query: 173 PQQQRGAAKEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGDGKTEQK 219
+++ + G +GP A G + +++ D TE++
Sbjct: 4982 SVEEKDKEADEEGGENGP--------ADQGFQPQEEEEREDSDTEEQ 5020
Score = 49.7 bits (117), Expect = 1e-05
Identities = 66/270 (24%), Positives = 103/270 (38%), Gaps = 23/270 (8%)
Query: 22 KRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNG-SLDLGGDSAGRSGAGLEQEAAA 80
K + + G +AE ER + D E+ + EP G S D + G + +
Sbjct: 4912 KEKPEEAGHEAE--ERGETETDQNES--QSPQEPEEGPSEDDKAEGEEEMDTGADDQDGD 4967
Query: 81 GGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGPMEEEEAASEDENGDDQGFQE 140
EE EE+++ + D E EE G G AD G +EE ED + ++Q +
Sbjct: 4968 AAQHPEEHSEEQQQSVEEKD---KEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEA 5024
Query: 141 GEDELGDEEEGAGDENGHGEQQPQ--PPATQQQQPQQQRGAAKEAAGKSSGPTSLFAVTV 198
E + G EN Q + A +++Q +++ G+ A ++ G S F +
Sbjct: 5025 LERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQL 5084
Query: 199 APPGARQGQQQA----GGDGKTEQKGGDKKRGV-KRPREDHGRGYFEYIEENKYSRAKSP 253
A + Q+ G E+ GD V KR R + E A+ P
Sbjct: 5085 ASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDTDSHAE------QGPAQQP 5138
Query: 254 QPPVEEED--EHFDDTVVCLDTYNCDLHFK 281
Q VE+ D EH D D+ K
Sbjct: 5139 QAQVEDADAFEHIKQGSDAYDAQTYDVASK 5168
Score = 42.0 bits (97), Expect = 0.002
Identities = 34/116 (29%), Positives = 60/116 (51%), Gaps = 11/116 (9%)
Query: 61 DLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMEL--GEENGAAGAADS 118
DL G+ A + L + DEEEE+ + EE G +D + EL ++N +G ++
Sbjct: 4765 DLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETG-PGMDEEDSELVAKDDNLDSGNSNK 4823
Query: 119 GPMEEEEAASEDENGDDQGFQEGEDELGDE-EEGAGDEN------GHGEQQPQPPA 167
++++ ++E D G Q GED++ ++ +E DEN G+ E+ P+P A
Sbjct: 4824 DKSQQDKKEEKEEAEADDGGQ-GEDKINEQIDERDYDENEVDPYHGNQEKVPEPEA 4878
Score = 41.2 bits (95), Expect = 0.004
Identities = 58/277 (20%), Positives = 101/277 (36%), Gaps = 52/277 (18%)
Query: 42 LDDEEAGGRPAMEPGNGSLDLG-GDSAGRSGAGLEQEAAAGGDEEEEEEEEE---EEGIS 97
L+++E + G G LD GD G L++ DEEE+EEEE+ EE
Sbjct: 4742 LEEQEEDDEKSDSEG-GDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGP 4800
Query: 98 ALDGDQMELGEENGAAGAADSGP-------MEEEEAASEDENG----------DDQGFQE 140
+D + EL ++ + +S EE+E A D+ G D++ + E
Sbjct: 4801 GMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDE 4860
Query: 141 GE--------------------DELG-DEEEGAGDENGHGEQQPQPPATQQQQPQQQRGA 179
E D+L D E+ G E+ E+ + + ++ ++ G
Sbjct: 4861 NEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGH 4920
Query: 180 AKEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGDGKTEQKGGDKKRGVKRPREDHGRGYF 239
E G++ + P +A G+ + + D+ + E+H
Sbjct: 4921 EAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQ 4980
Query: 240 EYIEE---------NKYSRAKSPQPPVEEEDEHFDDT 267
+ +EE + A P EEE+ DT
Sbjct: 4981 QSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDT 5017
Score = 35.4 bits (80), Expect = 0.21
Identities = 41/242 (16%), Positives = 94/242 (38%), Gaps = 26/242 (10%)
Query: 43 DDEEAGGRPAMEPGNGSLDLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGD 102
D E+ + ++ + ++++ D G+ G +E ++ + E + ++ + L+G+
Sbjct: 4710 DKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGE 4769
Query: 103 QMELGEENGAAGAADSGPMEEEEAASED-------------------ENGDDQGFQEGED 143
+ + +E + EEE+ +E+ ++G+ + +D
Sbjct: 4770 EADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQD 4829
Query: 144 ELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAAKEAAGKSSGPTSLFAVTVAPPGA 203
+ ++EE D+ G GE + ++ + + K P +L P
Sbjct: 4830 KKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEAL----DLPDDL 4885
Query: 204 RQGQQQAGGDGKTEQKGGDKKR--GVKRPREDHGRGYFEYIE-ENKYSRAKSPQPPVEEE 260
+ G T+ + G+++ +K E+ G E E E + ++SPQ P E
Sbjct: 4886 NLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGP 4945
Query: 261 DE 262
E
Sbjct: 4946 SE 4947
Score = 35.0 bits (79), Expect = 0.28
Identities = 42/209 (20%), Positives = 78/209 (37%), Gaps = 29/209 (13%)
Query: 44 DEEAGGRPAMEPGNGSLDLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQ 103
D E GG + G G D+ G E++ + +E+++E+ + S + G+
Sbjct: 4674 DYEGGG---IGEGEGMKDVSDQ------IGNEEQVEDTFQKGQEKDKEDPDSKSDIKGED 4724
Query: 104 MELGEENGAAGAADSGPMEEEEAASEDENGDDQG--FQEGEDELGDEEEGAGDENGHGEQ 161
+ G G +EE+E +DE D +G + +L EE DE G+
Sbjct: 4725 NAIEMSEDFDGKMHDGELEEQE--EDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDD 4782
Query: 162 QPQPPATQQQQPQQQRGAAKEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGDGKTEQKGG 221
+ ++ ++ G G + L A+ +G K + +
Sbjct: 4783 DEEEDEEEEDNKTEETG-----PGMDEEDSELV--------AKDDNLDSGNSNKDKSQQD 4829
Query: 222 DKKRGVKRPREDHGRG---YFEYIEENKY 247
K+ + +D G+G E I+E Y
Sbjct: 4830 KKEEKEEAEADDGGQGEDKINEQIDERDY 4858
>gi|12056465 fibrillarin [Homo sapiens]
Length = 321
Score = 58.5 bits (140), Expect = 2e-08
Identities = 39/84 (46%), Positives = 41/84 (48%), Gaps = 15/84 (17%)
Query: 683 RGGGHRGRGGFNMRGGNFRGGAPGNRGGYNRRGNMPQRG----GGGGGSGGIGYPYPRAP 738
RGGG GRGGF RGG RGG G GG R G RG GGGGG GG G
Sbjct: 8 RGGGFGGRGGFGDRGG--RGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGG------- 58
Query: 739 VFPGRGSYSNRGNYNRGGMPNRGN 762
G G + + GN RG RGN
Sbjct: 59 --RGGGGFHSGGNRGRGRGGKRGN 80
Score = 49.3 bits (116), Expect = 1e-05
Identities = 45/107 (42%), Positives = 48/107 (44%), Gaps = 41/107 (38%)
Query: 677 GKNQFNRGGGHRGRGGFNM---RGGNFRGGAPGNRGGYNRRGNMPQRGGGGGGSGGIGYP 733
G+ F GG GRGGF RGG FRG RG RGGGGGG GG G
Sbjct: 14 GRGGFGDRGGRGGRGGFGGGRGRGGGFRG-----RG----------RGGGGGGGGGGG-- 56
Query: 734 YPRAPVFPGRGSYSNRGNYNRGGMPNRGNYNQNFRGRGNNRGYKNQS 780
GRG G ++ GG NRG RGRG RG NQS
Sbjct: 57 -------GGRGG----GGFHSGG--NRG------RGRGGKRG--NQS 82
Score = 32.7 bits (73), Expect = 1.4
Identities = 23/62 (37%), Positives = 28/62 (45%), Gaps = 1/62 (1%)
Query: 683 RGGGHRGRGGFNMRGGNFRGGAPGNRGGYNRRGNMPQRGGGGGGSGGIGYPYPRAPVFPG 742
RG G G GG GG RGG + GG RG +RG G + + P+ VF
Sbjct: 41 RGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGRGRGGKRGNQSGKNVMV-EPHRHEGVFIC 99
Query: 743 RG 744
RG
Sbjct: 100 RG 101
>gi|4504445 heterogeneous nuclear ribonucleoprotein A1 isoform a
[Homo sapiens]
Length = 320
Score = 58.2 bits (139), Expect = 3e-08
Identities = 44/122 (36%), Positives = 55/122 (45%), Gaps = 13/122 (10%)
Query: 653 ESKKALPPEKKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNFRGGAPGNRGGYN 712
E +KAL ++ + S + ++ SG RGGG G F RGGNF G RGG+
Sbjct: 176 EVRKALSKQEMASASSSQRGRSGSGNFGGGRGGGFGGNDNFG-RGGNFSG-----RGGFG 229
Query: 713 RRGNMPQRGGGGGGSGGIGYP--YPRAPVFPGRGSYSNRGNYNRGGMPNRGNYNQNFRGR 770
RGGGG G G GY F G GSY++ GNYN NF GR
Sbjct: 230 -----GSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGR 284
Query: 771 GN 772
+
Sbjct: 285 SS 286
Score = 37.4 bits (85), Expect = 0.056
Identities = 33/97 (34%), Positives = 42/97 (43%), Gaps = 15/97 (15%)
Query: 674 NKSGKNQF--NRGGGH-----RGRGGFNMRGGNFRGGAPGNR-GGYNRRGNM--PQRGGG 723
N SG+ F +RGGG G GF G NF GG N G YN + + P +GG
Sbjct: 221 NFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGN 280
Query: 724 GGGS-----GGIGYPYPRAPVFPGRGSYSNRGNYNRG 755
GG GG G + + G G S+ +Y G
Sbjct: 281 FGGRSSGPYGGGGQYFAKPRNQGGYGGSSSSSSYGSG 317
>gi|56699482 hypothetical protein LOC25940 [Homo sapiens]
Length = 518
Score = 56.2 bits (134), Expect = 1e-07
Identities = 60/182 (32%), Positives = 77/182 (42%), Gaps = 44/182 (24%)
Query: 658 LPPEKKQNTGSKKSNKNKSGKNQFNRGG-GHRGRGGFNMRGGNFRGGAPGNRGGYNR--- 713
+PP +K+ G ++ + G RGG H GG RGG+ +GG G RGGY+
Sbjct: 319 MPPWQKRQDGPQQQTGGRGG----GRGGYEHSSYGG---RGGHEQGGGRGGRGGYDHGGR 371
Query: 714 ---RGNMPQRGGGGGGSGGIG----YPYPRAPVFPG--RGSYSNRGNYNRGGMP------ 758
RGN Q G GGSGG G Y + PG G +S+ G Y GG
Sbjct: 372 GGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSS-GGYQGGGYGGFQTSS 430
Query: 759 -------NRGNYNQNFR--------GRGNNRGYKNQSQGY-NQWQQGQFWGQKPWSQHYH 802
G Y Q+ R RG RG + G + QG WG + SQ+YH
Sbjct: 431 SYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGR-GSQNYH 489
Query: 803 QG 804
QG
Sbjct: 490 QG 491
Score = 48.5 bits (114), Expect = 2e-05
Identities = 39/123 (31%), Positives = 54/123 (43%), Gaps = 11/123 (8%)
Query: 664 QNTGSKKSNKNKSGKNQFNRGGGHRGRG--GF----NMRGGNFRGGAPGNRGGYNRRGNM 717
Q+ G + S G + + GG++G G GF + G ++GG Y G+
Sbjct: 395 QDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHH 454
Query: 718 PQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNR----GNYNQNFRGRGNN 773
RGGG GG GG G RA G G ++ NY++GG + G Y N G G
Sbjct: 455 GDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQ-NYHQGGQFEQHFQHGGYQYNHSGFGQG 513
Query: 774 RGY 776
R Y
Sbjct: 514 RHY 516
Score = 40.8 bits (94), Expect = 0.005
Identities = 35/110 (31%), Positives = 45/110 (40%), Gaps = 12/110 (10%)
Query: 702 GGAPGNRGGYNR-----RGNMPQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGG 756
GG G RGGY RG Q GGG GG GG Y GRG+ ++G + GG
Sbjct: 334 GGRGGGRGGYEHSSYGGRGGHEQ-GGGRGGRGG----YDHGGRGGGRGN-KHQGGWTDGG 387
Query: 757 MPNRGNYNQ-NFRGRGNNRGYKNQSQGYNQWQQGQFWGQKPWSQHYHQGY 805
G Y +R G G + +Q G + G + S + GY
Sbjct: 388 SGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGY 437
>gi|21735415 centromere protein B [Homo sapiens]
Length = 599
Score = 55.8 bits (133), Expect = 2e-07
Identities = 40/130 (30%), Positives = 57/130 (43%), Gaps = 10/130 (7%)
Query: 43 DDEEAGGRPAMEPGNGSLDLGGDSAGRSGAGLEQEAAAGGD-----EEEEEEEEEEEGIS 97
++EE G E G + GG+ G E+E GD EEEE+EE EG+
Sbjct: 416 EEEEGEGEEEEEEGEEEEEEGGEG---EELGEEEEVEEEGDVDSDEEEEEDEESSSEGLE 472
Query: 98 ALDGDQ--MELGEENGAAGAADSGPMEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDE 155
A D Q +E G GA GA + E+ D +E ++E DE+E D+
Sbjct: 473 AEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDD 532
Query: 156 NGHGEQQPQP 165
G++ P P
Sbjct: 533 EEDGDEVPVP 542
Score = 47.8 bits (112), Expect = 4e-05
Identities = 30/88 (34%), Positives = 41/88 (46%), Gaps = 9/88 (10%)
Query: 83 DEEEEEEEEEEEGISALDGDQMELGEENGAAG--------AADSGPMEEEEAASEDENGD 134
+EEEEEEEEEEEG + ++ E EE G G + G ++ +E EDE
Sbjct: 408 EEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESS 467
Query: 135 DQGFQEGEDELGDEEEGAGDENGHGEQQ 162
+G E ED E G +G Q+
Sbjct: 468 SEGL-EAEDWAQGVVEAGGSFGAYGAQE 494
Score = 46.2 bits (108), Expect = 1e-04
Identities = 30/89 (33%), Positives = 41/89 (46%), Gaps = 13/89 (14%)
Query: 68 GRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGPMEEEEAA 127
G A + + G+EEEEEEEEEEE EE + G EEEE
Sbjct: 391 GGPNATITTSLKSEGEEEEEEEEEEEE-------------EEGEGEEEEEEGEEEEEEGG 437
Query: 128 SEDENGDDQGFQEGEDELGDEEEGAGDEN 156
+E G+++ +E D DEEE +E+
Sbjct: 438 EGEELGEEEEVEEEGDVDSDEEEEEDEES 466
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 55.5 bits (132), Expect = 2e-07
Identities = 58/234 (24%), Positives = 100/234 (42%), Gaps = 23/234 (9%)
Query: 6 VNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAM------EPGNGS 59
V+ K +E K E +R +K L A+ RL ++ E +P +P +
Sbjct: 85 VSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRA 144
Query: 60 LDLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGI-----SALDGDQMELGEENGAAG 114
D + R G +++ A+ +EE EE G S+ D+ EN G
Sbjct: 145 KSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEG 204
Query: 115 AADSGPMEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQ 174
+ +EE+E ED D++ ++GE+E +EEE +E E+ Q ++ Q
Sbjct: 205 VEED--VEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEY-----EQDERDQ 257
Query: 175 QQRGAAKEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGDGKTEQKGGDKK-RGV 227
++ G + ++S S +V+ R G +G DG E+K K+ RG+
Sbjct: 258 KEEGNDYDTRSEASDSGS-ESVSFTDGSVRSG---SGTDGSDEKKKERKRARGI 307
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 55.5 bits (132), Expect = 2e-07
Identities = 58/234 (24%), Positives = 100/234 (42%), Gaps = 23/234 (9%)
Query: 6 VNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAM------EPGNGS 59
V+ K +E K E +R +K L A+ RL ++ E +P +P +
Sbjct: 85 VSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRA 144
Query: 60 LDLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGI-----SALDGDQMELGEENGAAG 114
D + R G +++ A+ +EE EE G S+ D+ EN G
Sbjct: 145 KSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEG 204
Query: 115 AADSGPMEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQ 174
+ +EE+E ED D++ ++GE+E +EEE +E E+ Q ++ Q
Sbjct: 205 VEED--VEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEY-----EQDERDQ 257
Query: 175 QQRGAAKEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGDGKTEQKGGDKK-RGV 227
++ G + ++S S +V+ R G +G DG E+K K+ RG+
Sbjct: 258 KEEGNDYDTRSEASDSGS-ESVSFTDGSVRSG---SGTDGSDEKKKERKRARGI 307
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 55.1 bits (131), Expect = 3e-07
Identities = 61/235 (25%), Positives = 89/235 (37%), Gaps = 34/235 (14%)
Query: 48 GGRPAMEPGNGSLDLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELG 107
GG PA+E +++ E+E +EEEEEEEEEEE + D+ E
Sbjct: 869 GGPPALEEDLTVININSSDE-------EEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYF 921
Query: 108 EENGAAGAADSGPMEEEEA-ASEDENGDDQGFQEGEDELGDEEEG-AGDENGHGE----- 160
EE EEEE E+E +D+ +E +E+ D E G AG E G
Sbjct: 922 EEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPT 981
Query: 161 -----QQPQPPATQQQQPQQQRG--------AAKEAAGKSSGPTSLFAVTVAPPGARQGQ 207
P+ P Q +P+ + G +E G + PT P A Q
Sbjct: 982 LPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPT-------LAPEALPSQ 1034
Query: 208 QQAGGDGKTEQKGGDKKRGVKRPREDHGRGYFEYIEENKYSRAKSPQPPVEEEDE 262
+ +G++ G + V+ E E+ P+ P EEE E
Sbjct: 1035 GEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEME 1089
Score = 42.4 bits (98), Expect = 0.002
Identities = 49/212 (23%), Positives = 86/212 (40%), Gaps = 33/212 (15%)
Query: 64 GDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGPMEE 123
G G LE++ +EEEEEEE + ++ E EE EE
Sbjct: 864 GTPGGGGPPALEEDLTVININSSDEEEEEEE-----EEEEEEEEEE------------EE 906
Query: 124 EEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQQ-----QRG 178
EE E+E +++ F+E E+E + EE +E G E++ + ++++ + + G
Sbjct: 907 EEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFG 966
Query: 179 AAKEAAGKSSGPTSLFAVTVAPPGA-----RQGQQQAGGDGKTEQKGGDKKRGVK----- 228
A + + P + PP + + + + G + E+ G +++RG
Sbjct: 967 TAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTL 1026
Query: 229 RPREDHGRGYFEYIEENKYSRAKSPQPPVEEE 260
P +G E E + PQ VEEE
Sbjct: 1027 APEALPSQGEVER-EGESPAAGPPPQELVEEE 1057
>gi|156151396 heterogeneous nuclear ribonucleoprotein R isoform 3
[Homo sapiens]
Length = 535
Score = 55.1 bits (131), Expect = 3e-07
Identities = 58/224 (25%), Positives = 88/224 (39%), Gaps = 63/224 (28%)
Query: 628 ECFDEITYVELQKEEAQKLLEQYKEESKKALPPEKK--QNTGSKKSNKNKSGKNQF---- 681
+ DE+ E++ EE + +L A PP+KK + +++++++ + ++ +
Sbjct: 291 KAMDEMNGKEIEGEEIEIVL---------AKPPDKKRKERQAARQASRSTAYEDYYYHPP 341
Query: 682 ----------NRGGGHRGRG----------------GFNMRGGNFRGGAPGNRGGYNRRG 715
RGGG G G G++ ++RGG GY+
Sbjct: 342 PRMPPPIRGRGRGGGRGGYGYPPDYYGYEDYYDDYYGYDYH--DYRGGYEDPYYGYDDGY 399
Query: 716 NMPQRGGGGGGSG------GIGYPYPR---------APVFPGRGSYSNRGN-----YNRG 755
+ RGGG GG G G G P PR AP+ P RGS RG RG
Sbjct: 400 AVRGRGGGRGGRGAPPPPRGRGAPPPRGRAGYSQRGAPLGPPRGSRGGRGGPAQQQRGRG 459
Query: 756 GMPNRGNYNQNFRGRGNNRGYKNQSQGYNQWQQGQFWGQKPWSQ 799
+RGN N G+ GY Q Q WG +P +Q
Sbjct: 460 SRGSRGNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWGSQPIAQ 503
Score = 44.3 bits (103), Expect = 5e-04
Identities = 48/141 (34%), Positives = 56/141 (39%), Gaps = 41/141 (29%)
Query: 683 RGGGHRGRGGFNMRGGNFRGGAPGNRG--GYNRRGNM--PQRGGGGGGSGGIGYPYPRAP 738
RGGG GRG G GAP RG GY++RG P RG GG G A
Sbjct: 404 RGGGRGGRGAPPPPRGR---GAPPPRGRAGYSQRGAPLGPPRGSRGGRGGP-------AQ 453
Query: 739 VFPGRGSYSNRGNY--NRGGMPNRGNYNQ--NFRGRGNNR-------------------- 774
GRGS +RGN N GG YNQ + R + NN+
Sbjct: 454 QQRGRGSRGSRGNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWGSQPIAQQPLQQGGDYS 513
Query: 775 ---GYKNQSQGYNQWQQGQFW 792
GY N +Q + Q GQ W
Sbjct: 514 GNYGYNNDNQEFYQDTYGQQW 534
>gi|156151394 heterogeneous nuclear ribonucleoprotein R isoform 1
[Homo sapiens]
Length = 636
Score = 55.1 bits (131), Expect = 3e-07
Identities = 58/224 (25%), Positives = 88/224 (39%), Gaps = 63/224 (28%)
Query: 628 ECFDEITYVELQKEEAQKLLEQYKEESKKALPPEKK--QNTGSKKSNKNKSGKNQF---- 681
+ DE+ E++ EE + +L A PP+KK + +++++++ + ++ +
Sbjct: 392 KAMDEMNGKEIEGEEIEIVL---------AKPPDKKRKERQAARQASRSTAYEDYYYHPP 442
Query: 682 ----------NRGGGHRGRG----------------GFNMRGGNFRGGAPGNRGGYNRRG 715
RGGG G G G++ ++RGG GY+
Sbjct: 443 PRMPPPIRGRGRGGGRGGYGYPPDYYGYEDYYDDYYGYDYH--DYRGGYEDPYYGYDDGY 500
Query: 716 NMPQRGGGGGGSG------GIGYPYPR---------APVFPGRGSYSNRGN-----YNRG 755
+ RGGG GG G G G P PR AP+ P RGS RG RG
Sbjct: 501 AVRGRGGGRGGRGAPPPPRGRGAPPPRGRAGYSQRGAPLGPPRGSRGGRGGPAQQQRGRG 560
Query: 756 GMPNRGNYNQNFRGRGNNRGYKNQSQGYNQWQQGQFWGQKPWSQ 799
+RGN N G+ GY Q Q WG +P +Q
Sbjct: 561 SRGSRGNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWGSQPIAQ 604
Score = 44.3 bits (103), Expect = 5e-04
Identities = 48/141 (34%), Positives = 56/141 (39%), Gaps = 41/141 (29%)
Query: 683 RGGGHRGRGGFNMRGGNFRGGAPGNRG--GYNRRGNM--PQRGGGGGGSGGIGYPYPRAP 738
RGGG GRG G GAP RG GY++RG P RG GG G A
Sbjct: 505 RGGGRGGRGAPPPPRGR---GAPPPRGRAGYSQRGAPLGPPRGSRGGRGGP-------AQ 554
Query: 739 VFPGRGSYSNRGNY--NRGGMPNRGNYNQ--NFRGRGNNR-------------------- 774
GRGS +RGN N GG YNQ + R + NN+
Sbjct: 555 QQRGRGSRGSRGNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWGSQPIAQQPLQQGGDYS 614
Query: 775 ---GYKNQSQGYNQWQQGQFW 792
GY N +Q + Q GQ W
Sbjct: 615 GNYGYNNDNQEFYQDTYGQQW 635
>gi|156151392 heterogeneous nuclear ribonucleoprotein R isoform 4
[Homo sapiens]
Length = 532
Score = 55.1 bits (131), Expect = 3e-07
Identities = 58/224 (25%), Positives = 88/224 (39%), Gaps = 63/224 (28%)
Query: 628 ECFDEITYVELQKEEAQKLLEQYKEESKKALPPEKK--QNTGSKKSNKNKSGKNQF---- 681
+ DE+ E++ EE + +L A PP+KK + +++++++ + ++ +
Sbjct: 288 KAMDEMNGKEIEGEEIEIVL---------AKPPDKKRKERQAARQASRSTAYEDYYYHPP 338
Query: 682 ----------NRGGGHRGRG----------------GFNMRGGNFRGGAPGNRGGYNRRG 715
RGGG G G G++ ++RGG GY+
Sbjct: 339 PRMPPPIRGRGRGGGRGGYGYPPDYYGYEDYYDDYYGYDYH--DYRGGYEDPYYGYDDGY 396
Query: 716 NMPQRGGGGGGSG------GIGYPYPR---------APVFPGRGSYSNRGN-----YNRG 755
+ RGGG GG G G G P PR AP+ P RGS RG RG
Sbjct: 397 AVRGRGGGRGGRGAPPPPRGRGAPPPRGRAGYSQRGAPLGPPRGSRGGRGGPAQQQRGRG 456
Query: 756 GMPNRGNYNQNFRGRGNNRGYKNQSQGYNQWQQGQFWGQKPWSQ 799
+RGN N G+ GY Q Q WG +P +Q
Sbjct: 457 SRGSRGNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWGSQPIAQ 500
Score = 44.3 bits (103), Expect = 5e-04
Identities = 48/141 (34%), Positives = 56/141 (39%), Gaps = 41/141 (29%)
Query: 683 RGGGHRGRGGFNMRGGNFRGGAPGNRG--GYNRRGNM--PQRGGGGGGSGGIGYPYPRAP 738
RGGG GRG G GAP RG GY++RG P RG GG G A
Sbjct: 401 RGGGRGGRGAPPPPRGR---GAPPPRGRAGYSQRGAPLGPPRGSRGGRGGP-------AQ 450
Query: 739 VFPGRGSYSNRGNY--NRGGMPNRGNYNQ--NFRGRGNNR-------------------- 774
GRGS +RGN N GG YNQ + R + NN+
Sbjct: 451 QQRGRGSRGSRGNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWGSQPIAQQPLQQGGDYS 510
Query: 775 ---GYKNQSQGYNQWQQGQFW 792
GY N +Q + Q GQ W
Sbjct: 511 GNYGYNNDNQEFYQDTYGQQW 531
>gi|5031755 heterogeneous nuclear ribonucleoprotein R isoform 2
[Homo sapiens]
Length = 633
Score = 55.1 bits (131), Expect = 3e-07
Identities = 58/224 (25%), Positives = 88/224 (39%), Gaps = 63/224 (28%)
Query: 628 ECFDEITYVELQKEEAQKLLEQYKEESKKALPPEKK--QNTGSKKSNKNKSGKNQF---- 681
+ DE+ E++ EE + +L A PP+KK + +++++++ + ++ +
Sbjct: 389 KAMDEMNGKEIEGEEIEIVL---------AKPPDKKRKERQAARQASRSTAYEDYYYHPP 439
Query: 682 ----------NRGGGHRGRG----------------GFNMRGGNFRGGAPGNRGGYNRRG 715
RGGG G G G++ ++RGG GY+
Sbjct: 440 PRMPPPIRGRGRGGGRGGYGYPPDYYGYEDYYDDYYGYDYH--DYRGGYEDPYYGYDDGY 497
Query: 716 NMPQRGGGGGGSG------GIGYPYPR---------APVFPGRGSYSNRGN-----YNRG 755
+ RGGG GG G G G P PR AP+ P RGS RG RG
Sbjct: 498 AVRGRGGGRGGRGAPPPPRGRGAPPPRGRAGYSQRGAPLGPPRGSRGGRGGPAQQQRGRG 557
Query: 756 GMPNRGNYNQNFRGRGNNRGYKNQSQGYNQWQQGQFWGQKPWSQ 799
+RGN N G+ GY Q Q WG +P +Q
Sbjct: 558 SRGSRGNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWGSQPIAQ 601
Score = 44.3 bits (103), Expect = 5e-04
Identities = 48/141 (34%), Positives = 56/141 (39%), Gaps = 41/141 (29%)
Query: 683 RGGGHRGRGGFNMRGGNFRGGAPGNRG--GYNRRGNM--PQRGGGGGGSGGIGYPYPRAP 738
RGGG GRG G GAP RG GY++RG P RG GG G A
Sbjct: 502 RGGGRGGRGAPPPPRGR---GAPPPRGRAGYSQRGAPLGPPRGSRGGRGGP-------AQ 551
Query: 739 VFPGRGSYSNRGNY--NRGGMPNRGNYNQ--NFRGRGNNR-------------------- 774
GRGS +RGN N GG YNQ + R + NN+
Sbjct: 552 QQRGRGSRGSRGNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWGSQPIAQQPLQQGGDYS 611
Query: 775 ---GYKNQSQGYNQWQQGQFW 792
GY N +Q + Q GQ W
Sbjct: 612 GNYGYNNDNQEFYQDTYGQQW 632
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 54.7 bits (130), Expect = 3e-07
Identities = 56/260 (21%), Positives = 106/260 (40%), Gaps = 41/260 (15%)
Query: 5 PVNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSLDLGG 64
P+ + K+ + K E K ++ K ++ E++E + ++DE++ A+ L
Sbjct: 429 PITISS-KIQKPKVEAPKLKVQHKFVE-EIIE--ETKVEDEKSEMEEALTAITEEL---- 480
Query: 65 DSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISA----LDGDQMELGEENGAAGAADSGP 120
+++E +E+EEE E EEE ++A + E+ EE G
Sbjct: 481 ------AVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGE-------- 526
Query: 121 MEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAA 180
+EEE E+E +D+G + + E G E+ E GEQ+ + + + +
Sbjct: 527 -KEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEE 585
Query: 181 KEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGDGKTEQKGGDKKRGVKRPREDHGRGYFE 240
K+ KS + +++ D K E+ K K P E+ G+
Sbjct: 586 KKVEEKSEEVAT--------------KEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVP 631
Query: 241 YIEENKYSRAKSPQPPVEEE 260
+ ++ P+ PVEE+
Sbjct: 632 KSPVEEKGKSPVPKSPVEEK 651
Score = 51.2 bits (121), Expect = 4e-06
Identities = 62/271 (22%), Positives = 106/271 (39%), Gaps = 39/271 (14%)
Query: 6 VNVKKLKVSE--LKEELKKRRLSDKGLKAELMERLQAALDD---------EEAGGRPAME 54
V KLKV ++E +++ ++ D+ K+E+ E L A ++ +EA E
Sbjct: 441 VEAPKLKVQHKFVEEIIEETKVEDE--KSEMEEALTAITEELAVSMKEEKKEAAEEKEEE 498
Query: 55 PGNGSLDLGGDSAGRSGAGLEQEAAAG------GDEEEEEEEEEEEGISALDGDQMELGE 108
P ++ + E + G G EEEEEE+E + A +G + G
Sbjct: 499 PEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGS 558
Query: 109 ENGAAGAADSGPMEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPAT 168
G + G E E E E +++ +E +E+ +EE D ++ + P
Sbjct: 559 SEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVP 618
Query: 169 QQQQPQQQRGAAKEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGDGKTEQKGGDKKRGVK 228
+ + E GKS P S P +G+ E+KG K K
Sbjct: 619 K---------SPVEEKGKSPVPKS--------PVEEKGKSPV-PKSPVEEKG--KSPVPK 658
Query: 229 RPREDHGRGYFEYIEENKYSRAKSPQPPVEE 259
P E+ G+ + +++ P+ PVEE
Sbjct: 659 SPVEEKGKSPVSKSPVEEKAKSPVPKSPVEE 689
Score = 35.4 bits (80), Expect = 0.21
Identities = 66/297 (22%), Positives = 110/297 (37%), Gaps = 76/297 (25%)
Query: 4 SPVNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSLDLG 63
SPV K E+KEE ++ ++G + E E A D E GG + + G+ + G
Sbjct: 511 SPV---KATAPEVKEEEGEKE-EEEGQEEEEEEDEGAKSDQAEEGG--SEKEGSSEKEEG 564
Query: 64 GDSAGRSGAGLEQEAAAGGDEEEEEEEE-------------------------------- 91
G + A E E A +E++ EE+
Sbjct: 565 EQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEE 624
Query: 92 -----------EEEGISALDGDQMELG----------EENGAAGAADSGPMEE------- 123
EE+G S + +E EE G + + S P+EE
Sbjct: 625 KGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKS-PVEEKAKSPVP 683
Query: 124 ----EEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGA 179
EEA S+ E G + +E E E+ + + E + + P + + P ++
Sbjct: 684 KSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAV 743
Query: 180 AKEAAGKSSGPTSLFAVTVA---PPGARQGQQQAGGDGKTEQKGGDKKRGVKRPRED 233
A+ S L T P + +++AGG+G +E++G DK G K R++
Sbjct: 744 AEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDK--GAKGSRKE 798
Score = 34.3 bits (77), Expect = 0.47
Identities = 40/159 (25%), Positives = 67/159 (42%), Gaps = 20/159 (12%)
Query: 4 SPVNVKKLKVS-----ELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNG 58
SPV K K + +EE K+ + + K K E E + +++ P E
Sbjct: 685 SPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVA 744
Query: 59 SLDLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADS 118
+ S LE+E G ++E+E+E+ G +G E G + GA G+
Sbjct: 745 EVVTITKSVK---VHLEKETKEEGKPLQQEKEKEKAGG---EGGSEEEGSDKGAKGS--- 795
Query: 119 GPMEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENG 157
+E+ A NG+ +G +E E E ++ G +E G
Sbjct: 796 ---RKEDIAV---NGEVEGKEEVEQETKEKGSGREEEKG 828
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 54.7 bits (130), Expect = 3e-07
Identities = 56/260 (21%), Positives = 106/260 (40%), Gaps = 41/260 (15%)
Query: 5 PVNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSLDLGG 64
P+ + K+ + K E K ++ K ++ E++E + ++DE++ A+ L
Sbjct: 53 PITISS-KIQKPKVEAPKLKVQHKFVE-EIIE--ETKVEDEKSEMEEALTAITEEL---- 104
Query: 65 DSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISA----LDGDQMELGEENGAAGAADSGP 120
+++E +E+EEE E EEE ++A + E+ EE G
Sbjct: 105 ------AVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGE-------- 150
Query: 121 MEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAA 180
+EEE E+E +D+G + + E G E+ E GEQ+ + + + +
Sbjct: 151 -KEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEE 209
Query: 181 KEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGDGKTEQKGGDKKRGVKRPREDHGRGYFE 240
K+ KS + +++ D K E+ K K P E+ G+
Sbjct: 210 KKVEEKSEEVAT--------------KEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVP 255
Query: 241 YIEENKYSRAKSPQPPVEEE 260
+ ++ P+ PVEE+
Sbjct: 256 KSPVEEKGKSPVPKSPVEEK 275
Score = 51.2 bits (121), Expect = 4e-06
Identities = 62/271 (22%), Positives = 106/271 (39%), Gaps = 39/271 (14%)
Query: 6 VNVKKLKVSE--LKEELKKRRLSDKGLKAELMERLQAALDD---------EEAGGRPAME 54
V KLKV ++E +++ ++ D+ K+E+ E L A ++ +EA E
Sbjct: 65 VEAPKLKVQHKFVEEIIEETKVEDE--KSEMEEALTAITEELAVSMKEEKKEAAEEKEEE 122
Query: 55 PGNGSLDLGGDSAGRSGAGLEQEAAAG------GDEEEEEEEEEEEGISALDGDQMELGE 108
P ++ + E + G G EEEEEE+E + A +G + G
Sbjct: 123 PEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGS 182
Query: 109 ENGAAGAADSGPMEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPAT 168
G + G E E E E +++ +E +E+ +EE D ++ + P
Sbjct: 183 SEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVP 242
Query: 169 QQQQPQQQRGAAKEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGDGKTEQKGGDKKRGVK 228
+ + E GKS P S P +G+ E+KG K K
Sbjct: 243 K---------SPVEEKGKSPVPKS--------PVEEKGKSPV-PKSPVEEKG--KSPVPK 282
Query: 229 RPREDHGRGYFEYIEENKYSRAKSPQPPVEE 259
P E+ G+ + +++ P+ PVEE
Sbjct: 283 SPVEEKGKSPVSKSPVEEKAKSPVPKSPVEE 313
Score = 35.4 bits (80), Expect = 0.21
Identities = 66/297 (22%), Positives = 110/297 (37%), Gaps = 76/297 (25%)
Query: 4 SPVNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSLDLG 63
SPV K E+KEE ++ ++G + E E A D E GG + + G+ + G
Sbjct: 135 SPV---KATAPEVKEEEGEKE-EEEGQEEEEEEDEGAKSDQAEEGG--SEKEGSSEKEEG 188
Query: 64 GDSAGRSGAGLEQEAAAGGDEEEEEEEE-------------------------------- 91
G + A E E A +E++ EE+
Sbjct: 189 EQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEE 248
Query: 92 -----------EEEGISALDGDQMELG----------EENGAAGAADSGPMEE------- 123
EE+G S + +E EE G + + S P+EE
Sbjct: 249 KGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKS-PVEEKAKSPVP 307
Query: 124 ----EEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGA 179
EEA S+ E G + +E E E+ + + E + + P + + P ++
Sbjct: 308 KSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAV 367
Query: 180 AKEAAGKSSGPTSLFAVTVA---PPGARQGQQQAGGDGKTEQKGGDKKRGVKRPRED 233
A+ S L T P + +++AGG+G +E++G DK G K R++
Sbjct: 368 AEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDK--GAKGSRKE 422
Score = 34.3 bits (77), Expect = 0.47
Identities = 40/159 (25%), Positives = 67/159 (42%), Gaps = 20/159 (12%)
Query: 4 SPVNVKKLKVS-----ELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNG 58
SPV K K + +EE K+ + + K K E E + +++ P E
Sbjct: 309 SPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVA 368
Query: 59 SLDLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADS 118
+ S LE+E G ++E+E+E+ G +G E G + GA G+
Sbjct: 369 EVVTITKSVK---VHLEKETKEEGKPLQQEKEKEKAGG---EGGSEEEGSDKGAKGS--- 419
Query: 119 GPMEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENG 157
+E+ A NG+ +G +E E E ++ G +E G
Sbjct: 420 ---RKEDIAV---NGEVEGKEEVEQETKEKGSGREEEKG 452
>gi|228008295 synaptotagmin binding, cytoplasmic RNA interacting
protein isoform 4 [Homo sapiens]
Length = 588
Score = 53.9 bits (128), Expect = 6e-07
Identities = 64/221 (28%), Positives = 82/221 (37%), Gaps = 60/221 (27%)
Query: 636 VELQKEEAQKLLEQYKEESKKALPPEKKQNTGSKKSNKNKSGKNQF-------------- 681
V+ +E K LE E A PP++K+ ++ + ++ KNQ
Sbjct: 350 VKAMEEMNGKDLEGENIEIVFAKPPDQKRK---ERKAQRQAAKNQMYDDYYYYGPPHMPP 406
Query: 682 -NRGGGHRGRGGF---------------------NMRGG---------NFRGGAPGNRGG 710
RG G GRGG+ N RGG +F+ GA G RGG
Sbjct: 407 PTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGGYEDPYYGYEDFQVGARG-RGG 465
Query: 711 YNRRGNMPQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRGNYNQNFRG- 769
RG P RG G G R RG RG G RG + RG
Sbjct: 466 RGARGAAPSRGRGAAPPRGRAGYSQRGGPGSARGVRGARG----GAQQQRGRGVRGARGG 521
Query: 770 RGNNRGYKNQSQGYNQ------WQQGQFWGQKPWSQHYHQG 804
RG N G K ++ GYNQ Q WG +P +Q QG
Sbjct: 522 RGGNVGGKRKADGYNQPDSKRRQTNNQNWGSQPIAQQPLQG 562
Score = 43.5 bits (101), Expect = 8e-04
Identities = 41/133 (30%), Positives = 51/133 (38%), Gaps = 30/133 (22%)
Query: 686 GHRGRGGFNMRGG---NFRGGAPGN-RGGYNRRGNMPQRGGGGGGSGGIGYPYPRAPVFP 741
G RGRGG RG RG AP R GY++RG G G GG R
Sbjct: 459 GARGRGGRGARGAAPSRGRGAAPPRGRAGYSQRGGPGSARGVRGARGGAQQQRGRGV--- 515
Query: 742 GRGSYSNRGN----------YNRGGMPNRGNYNQNFRGR------------GNNRGYKNQ 779
RG+ RG YN+ R NQN+ + N GYK++
Sbjct: 516 -RGARGGRGGNVGGKRKADGYNQPDSKRRQTNNQNWGSQPIAQQPLQGGDHSGNYGYKSE 574
Query: 780 SQGYNQWQQGQFW 792
+Q + Q GQ W
Sbjct: 575 NQEFYQDTFGQQW 587
>gi|228008291 synaptotagmin binding, cytoplasmic RNA interacting
protein isoform 1 [Homo sapiens]
Length = 623
Score = 53.9 bits (128), Expect = 6e-07
Identities = 64/221 (28%), Positives = 82/221 (37%), Gaps = 60/221 (27%)
Query: 636 VELQKEEAQKLLEQYKEESKKALPPEKKQNTGSKKSNKNKSGKNQF-------------- 681
V+ +E K LE E A PP++K+ ++ + ++ KNQ
Sbjct: 385 VKAMEEMNGKDLEGENIEIVFAKPPDQKRK---ERKAQRQAAKNQMYDDYYYYGPPHMPP 441
Query: 682 -NRGGGHRGRGGF---------------------NMRGG---------NFRGGAPGNRGG 710
RG G GRGG+ N RGG +F+ GA G RGG
Sbjct: 442 PTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGGYEDPYYGYEDFQVGARG-RGG 500
Query: 711 YNRRGNMPQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRGNYNQNFRG- 769
RG P RG G G R RG RG G RG + RG
Sbjct: 501 RGARGAAPSRGRGAAPPRGRAGYSQRGGPGSARGVRGARG----GAQQQRGRGVRGARGG 556
Query: 770 RGNNRGYKNQSQGYNQ------WQQGQFWGQKPWSQHYHQG 804
RG N G K ++ GYNQ Q WG +P +Q QG
Sbjct: 557 RGGNVGGKRKADGYNQPDSKRRQTNNQNWGSQPIAQQPLQG 597
Score = 43.5 bits (101), Expect = 8e-04
Identities = 41/133 (30%), Positives = 51/133 (38%), Gaps = 30/133 (22%)
Query: 686 GHRGRGGFNMRGG---NFRGGAPGN-RGGYNRRGNMPQRGGGGGGSGGIGYPYPRAPVFP 741
G RGRGG RG RG AP R GY++RG G G GG R
Sbjct: 494 GARGRGGRGARGAAPSRGRGAAPPRGRAGYSQRGGPGSARGVRGARGGAQQQRGRGV--- 550
Query: 742 GRGSYSNRGN----------YNRGGMPNRGNYNQNFRGR------------GNNRGYKNQ 779
RG+ RG YN+ R NQN+ + N GYK++
Sbjct: 551 -RGARGGRGGNVGGKRKADGYNQPDSKRRQTNNQNWGSQPIAQQPLQGGDHSGNYGYKSE 609
Query: 780 SQGYNQWQQGQFW 792
+Q + Q GQ W
Sbjct: 610 NQEFYQDTFGQQW 622
>gi|4504487 histidine rich calcium binding protein precursor [Homo
sapiens]
Length = 699
Score = 53.9 bits (128), Expect = 6e-07
Identities = 51/207 (24%), Positives = 86/207 (41%), Gaps = 31/207 (14%)
Query: 83 DEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGPMEEEEAASEDENGDDQGFQEGE 142
D EEE+E+EE+ G D + E GE+ G+ D +E+E E+ +G +E E
Sbjct: 481 DSEEEKEKEEDPGSHEEDDESSEQGEKGTHHGSRD----QEDEEDEEEGHGLSLNQEEEE 536
Query: 143 DELGDEEEGAGDENGHGEQ----QPQPPATQQQQPQQQRGAAKEAAGKSSGPTSLFAVTV 198
+E +EEE DE E+ P P +++ +++ G ++ + P L
Sbjct: 537 EEDKEEEEEEEDEERREERAEVGAPLSPDHSEEEEEEEEGLEEDEPRFTIIPNPL----- 591
Query: 199 APPGARQGQQQAGGDGKTEQKGGDKKRGVKRPREDHGR-------GYFEYIEENKYSRAK 251
+++AGG E+ G D + +++G GY + N+ + +
Sbjct: 592 ------DRREEAGGASSEEESGEDTG---PQDAQEYGNYQPGSLCGYCSFC--NRCTECE 640
Query: 252 SPQPPVEEEDEHFDDTVVCLDTYNCDL 278
S E EH D C Y C L
Sbjct: 641 SCHCDEENMGEHCDQCQHCQFCYLCPL 667
Score = 38.9 bits (89), Expect = 0.019
Identities = 40/152 (26%), Positives = 53/152 (34%), Gaps = 25/152 (16%)
Query: 36 ERLQAALDDEEAGGRPAMEPGNGSLDLGGDSAGRSGAGLEQEAAAGGDEEEE-------- 87
+R DD E +PG+ D G G ++EEE
Sbjct: 473 DRSHLRKDDSEEEKEKEEDPGSHEEDDESSEQGEKGTHHGSRDQEDEEDEEEGHGLSLNQ 532
Query: 88 EEEEEEEGISALDGDQMELGEENGAAGAA-----DSGPMEEEEAASEDE----------- 131
EEEEEE+ + + E EE GA EEEE EDE
Sbjct: 533 EEEEEEDKEEEEEEEDEERREERAEVGAPLSPDHSEEEEEEEEGLEEDEPRFTIIPNPLD 592
Query: 132 NGDDQGFQEGEDELGDEEEGAGDENGHGEQQP 163
++ G E+E G E+ G D +G QP
Sbjct: 593 RREEAGGASSEEESG-EDTGPQDAQEYGNYQP 623
Score = 38.5 bits (88), Expect = 0.025
Identities = 28/90 (31%), Positives = 39/90 (43%), Gaps = 9/90 (10%)
Query: 84 EEEEEEEEEEEGISALDGDQMELGEENGAA-------GAADSGPMEEEEAASEDENGDDQ 136
EEEEEEEEEEE S G Q +G+ G GP + ED++ DD
Sbjct: 193 EEEEEEEEEEEEASTEYGHQAHRHRGHGSEEDEDVSDGHHHHGPSHRHQGHEEDDDDDDD 252
Query: 137 GFQEGEDELGDEE--EGAGDENGHGEQQPQ 164
+ +D+ E A GHG ++ +
Sbjct: 253 DDDDDDDDDVSIEYRHQAHRHQGHGIEEDE 282
Score = 35.8 bits (81), Expect = 0.16
Identities = 27/109 (24%), Positives = 39/109 (35%), Gaps = 8/109 (7%)
Query: 63 GGDSAGRSGAGLEQEAAAGGDEEE--------EEEEEEEEGISALDGDQMELGEENGAAG 114
GG + G G G E + ++E+E+E +S+ + G G
Sbjct: 128 GGQARGHRGHGSEDTEDSAEHRHHLPSHRSHSHQDEDEDEVVSSEHHHHILRHGHRGHDG 187
Query: 115 AADSGPMEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQP 163
D G EEEE E+E + G Q EE +GH P
Sbjct: 188 EDDEGEEEEEEEEEEEEASTEYGHQAHRHRGHGSEEDEDVSDGHHHHGP 236
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.133 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,758,933
Number of Sequences: 37866
Number of extensions: 2264509
Number of successful extensions: 33150
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 442
Number of HSP's successfully gapped in prelim test: 911
Number of HSP's that attempted gapping in prelim test: 15406
Number of HSP's gapped (non-prelim): 8444
length of query: 806
length of database: 18,247,518
effective HSP length: 110
effective length of query: 696
effective length of database: 14,082,258
effective search space: 9801251568
effective search space used: 9801251568
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.