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Search of human proteins with 7662234
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7662234 rab11-family interacting protein 3 isoform 1 [Homo
sapiens]
(756 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7662234 rab11-family interacting protein 3 isoform 1 [Homo sa... 1521 0.0
gi|214010165 rab11-family interacting protein 3 isoform 2 [Homo ... 888 0.0
gi|28195388 RAB11 family interacting protein 4 (class II) [Homo ... 386 e-107
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 77 8e-14
gi|111955162 5-azacytidine induced 1 isoform b [Homo sapiens] 74 5e-13
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 74 7e-13
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 74 7e-13
gi|55770834 centromere protein F [Homo sapiens] 73 1e-12
gi|237858621 polyamine modulated factor 1 binding protein 1 isof... 71 3e-12
gi|237858619 polyamine modulated factor 1 binding protein 1 isof... 71 3e-12
gi|110347443 TATA element modulatory factor 1 [Homo sapiens] 70 9e-12
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 69 2e-11
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 68 3e-11
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 68 4e-11
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 68 4e-11
gi|34577114 cytomatrix protein p110 [Homo sapiens] 68 4e-11
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 67 5e-11
gi|14165274 golgi-associated microtubule-binding protein HOOK3 [... 67 6e-11
gi|148746195 trichohyalin [Homo sapiens] 67 8e-11
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] 66 1e-10
gi|111955084 5-azacytidine induced 1 isoform a [Homo sapiens] 66 1e-10
gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo sapi... 65 2e-10
gi|41872583 Rho-associated, coiled-coil containing protein kinas... 65 3e-10
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 64 4e-10
gi|4502443 dystonin isoform 1e precursor [Homo sapiens] 64 4e-10
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 64 4e-10
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 64 5e-10
gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sap... 64 5e-10
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 64 5e-10
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 64 5e-10
>gi|7662234 rab11-family interacting protein 3 isoform 1 [Homo
sapiens]
Length = 756
Score = 1521 bits (3937), Expect = 0.0
Identities = 756/756 (100%), Positives = 756/756 (100%)
Query: 1 MASAPPASPPGSEPPGPDPEPGGPDGPGAAQLAPGPAELRLGAPVGGPDPQSPGLDEPAP 60
MASAPPASPPGSEPPGPDPEPGGPDGPGAAQLAPGPAELRLGAPVGGPDPQSPGLDEPAP
Sbjct: 1 MASAPPASPPGSEPPGPDPEPGGPDGPGAAQLAPGPAELRLGAPVGGPDPQSPGLDEPAP 60
Query: 61 GAAADGGARWSAGPAPGLEGGPRDPGPSAPPPRSGPRGQLASPDAPGPGPRSEAPLPELD 120
GAAADGGARWSAGPAPGLEGGPRDPGPSAPPPRSGPRGQLASPDAPGPGPRSEAPLPELD
Sbjct: 61 GAAADGGARWSAGPAPGLEGGPRDPGPSAPPPRSGPRGQLASPDAPGPGPRSEAPLPELD 120
Query: 121 PLFSWTEEPEECGPASCPESAPFRLQGSSSSHRARGEVDVFSPFPAPTAGELALEQGPGS 180
PLFSWTEEPEECGPASCPESAPFRLQGSSSSHRARGEVDVFSPFPAPTAGELALEQGPGS
Sbjct: 121 PLFSWTEEPEECGPASCPESAPFRLQGSSSSHRARGEVDVFSPFPAPTAGELALEQGPGS 180
Query: 181 PPQPSDLSQTHPLPSEPVGSQEDGPRLRAVFDALDGDGDGFVRIEDFIQFATVYGAEQVK 240
PPQPSDLSQTHPLPSEPVGSQEDGPRLRAVFDALDGDGDGFVRIEDFIQFATVYGAEQVK
Sbjct: 181 PPQPSDLSQTHPLPSEPVGSQEDGPRLRAVFDALDGDGDGFVRIEDFIQFATVYGAEQVK 240
Query: 241 DLTKYLDPSGLGVISFEDFYQGITAIRNGDPDGQCYGGVASAQDEEPLACPDEFDDFVTY 300
DLTKYLDPSGLGVISFEDFYQGITAIRNGDPDGQCYGGVASAQDEEPLACPDEFDDFVTY
Sbjct: 241 DLTKYLDPSGLGVISFEDFYQGITAIRNGDPDGQCYGGVASAQDEEPLACPDEFDDFVTY 300
Query: 301 EANEVTDSAYMGSESTYSECETFTDEDTSTLVHPELQPEGDADSAGGSAVPSECLDAMEE 360
EANEVTDSAYMGSESTYSECETFTDEDTSTLVHPELQPEGDADSAGGSAVPSECLDAMEE
Sbjct: 301 EANEVTDSAYMGSESTYSECETFTDEDTSTLVHPELQPEGDADSAGGSAVPSECLDAMEE 360
Query: 361 PDHGALLLLPGRPHPHGQSVITVIGGEEHFEDYGEGSEAELSPETLCNGQLGCSDPAFLT 420
PDHGALLLLPGRPHPHGQSVITVIGGEEHFEDYGEGSEAELSPETLCNGQLGCSDPAFLT
Sbjct: 361 PDHGALLLLPGRPHPHGQSVITVIGGEEHFEDYGEGSEAELSPETLCNGQLGCSDPAFLT 420
Query: 421 PSPTKRLSSKKVARYLHQSGALTMEALEDPSPELMEGPEEDIADKVVFLERRVLELEKDT 480
PSPTKRLSSKKVARYLHQSGALTMEALEDPSPELMEGPEEDIADKVVFLERRVLELEKDT
Sbjct: 421 PSPTKRLSSKKVARYLHQSGALTMEALEDPSPELMEGPEEDIADKVVFLERRVLELEKDT 480
Query: 481 AATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELLCKMEREKSIE 540
AATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELLCKMEREKSIE
Sbjct: 481 AATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELLCKMEREKSIE 540
Query: 541 IENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLRLSEEQENKRRM 600
IENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLRLSEEQENKRRM
Sbjct: 541 IENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLRLSEEQENKRRM 600
Query: 601 GDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARE 660
GDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARE
Sbjct: 601 GDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARE 660
Query: 661 SELEQEVRRLKQDNRNLKEQNEELNGQIITLSIQGAKSLFSTAFSESLAAEISSVSRDEL 720
SELEQEVRRLKQDNRNLKEQNEELNGQIITLSIQGAKSLFSTAFSESLAAEISSVSRDEL
Sbjct: 661 SELEQEVRRLKQDNRNLKEQNEELNGQIITLSIQGAKSLFSTAFSESLAAEISSVSRDEL 720
Query: 721 MEAIQKQEEINFRLQDYIDRIIVAIMETNPSILEVK 756
MEAIQKQEEINFRLQDYIDRIIVAIMETNPSILEVK
Sbjct: 721 MEAIQKQEEINFRLQDYIDRIIVAIMETNPSILEVK 756
>gi|214010165 rab11-family interacting protein 3 isoform 2 [Homo
sapiens]
Length = 460
Score = 888 bits (2295), Expect = 0.0
Identities = 455/456 (99%), Positives = 456/456 (100%)
Query: 301 EANEVTDSAYMGSESTYSECETFTDEDTSTLVHPELQPEGDADSAGGSAVPSECLDAMEE 360
+ANEVTDSAYMGSESTYSECETFTDEDTSTLVHPELQPEGDADSAGGSAVPSECLDAMEE
Sbjct: 5 KANEVTDSAYMGSESTYSECETFTDEDTSTLVHPELQPEGDADSAGGSAVPSECLDAMEE 64
Query: 361 PDHGALLLLPGRPHPHGQSVITVIGGEEHFEDYGEGSEAELSPETLCNGQLGCSDPAFLT 420
PDHGALLLLPGRPHPHGQSVITVIGGEEHFEDYGEGSEAELSPETLCNGQLGCSDPAFLT
Sbjct: 65 PDHGALLLLPGRPHPHGQSVITVIGGEEHFEDYGEGSEAELSPETLCNGQLGCSDPAFLT 124
Query: 421 PSPTKRLSSKKVARYLHQSGALTMEALEDPSPELMEGPEEDIADKVVFLERRVLELEKDT 480
PSPTKRLSSKKVARYLHQSGALTMEALEDPSPELMEGPEEDIADKVVFLERRVLELEKDT
Sbjct: 125 PSPTKRLSSKKVARYLHQSGALTMEALEDPSPELMEGPEEDIADKVVFLERRVLELEKDT 184
Query: 481 AATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELLCKMEREKSIE 540
AATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELLCKMEREKSIE
Sbjct: 185 AATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELLCKMEREKSIE 244
Query: 541 IENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLRLSEEQENKRRM 600
IENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLRLSEEQENKRRM
Sbjct: 245 IENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLRLSEEQENKRRM 304
Query: 601 GDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARE 660
GDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARE
Sbjct: 305 GDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARE 364
Query: 661 SELEQEVRRLKQDNRNLKEQNEELNGQIITLSIQGAKSLFSTAFSESLAAEISSVSRDEL 720
SELEQEVRRLKQDNRNLKEQNEELNGQIITLSIQGAKSLFSTAFSESLAAEISSVSRDEL
Sbjct: 365 SELEQEVRRLKQDNRNLKEQNEELNGQIITLSIQGAKSLFSTAFSESLAAEISSVSRDEL 424
Query: 721 MEAIQKQEEINFRLQDYIDRIIVAIMETNPSILEVK 756
MEAIQKQEEINFRLQDYIDRIIVAIMETNPSILEVK
Sbjct: 425 MEAIQKQEEINFRLQDYIDRIIVAIMETNPSILEVK 460
>gi|28195388 RAB11 family interacting protein 4 (class II) [Homo
sapiens]
Length = 637
Score = 386 bits (992), Expect = e-107
Identities = 250/621 (40%), Positives = 357/621 (57%), Gaps = 74/621 (11%)
Query: 206 RLRAVFDALDGDGDGFVRIEDFIQFATVYG-AEQVKDLTKYLDPSGLGVISFEDFYQGIT 264
RLR VF+ D DGF+R+E +G E+V+ L KYLDP+ LG I+F+DF +G+
Sbjct: 20 RLREVFEVCGRDPDGFLRVERVAALGLRFGQGEEVEKLVKYLDPNDLGRINFKDFCRGVF 79
Query: 265 AIRNGDPDGQCYGGVASAQDEEPLACPDEFDDFVTYEANEVTDSAYMGSESTYSECETFT 324
A++ + + V S + L C E D V + +EVT + E E F
Sbjct: 80 AMKGCE---ELLKDVLSVESAGTLPCAPEIPDCVE-QGSEVTGPTFADGELIPREPGFFP 135
Query: 325 D--EDTSTLVHPELQPEGDADSAGGSAVPSE-CLDAMEEPDHG--ALLLLPGRPHPHGQS 379
+ E+ TL PE E DS S E + + E D G L L + H S
Sbjct: 136 EDEEEAMTLAPPEGPQELYTDSPMESTQSLEGSVGSPAEKDGGLGGLFLPEDKSLVHTPS 195
Query: 380 VIT----------VIGGEEHFEDYGEGSEAELSPETLCN---------GQLGCS--DPAF 418
+ T +I EE FEDYGEG + + +P + C LG S A
Sbjct: 196 MTTSDLSTHSTTSLISNEEQFEDYGEGDDVDCAPSSPCPDDETRTNVYSDLGSSVSSSAG 255
Query: 419 LTP---------------------------------------SPTKRLSSKKVARYLHQS 439
TP SP +++SS R L S
Sbjct: 256 QTPRKMRHVYNSELLDVYCSQCCKKINLLNDLEARLKNLKANSPNRKISSTAFGRQLMHS 315
Query: 440 GALTME--ALEDPSPELMEGPEEDIADKVVFLERRVLELEKDTAATGEQHSRLRQENLQL 497
+ + ED + ++ + DI +KV FLE++V ELE D+ G+ S+L+QEN QL
Sbjct: 316 SNFSSSNGSTEDLFRDSIDSCDNDITEKVSFLEKKVTELENDSLTNGDLKSKLKQENTQL 375
Query: 498 VHRANALEEQLKEQELRACEMVLEETRRQKELLCKMEREKSIEIENLQTRLQQLDEENSE 557
VHR + LEE +K+QE A + + EE RR +E K+EREK+ E+E L R+QQL+EEN+E
Sbjct: 376 VHRVHELEEMVKDQETTAEQALEEEARRHREAYGKLEREKATEVELLNARVQQLEEENTE 435
Query: 558 LRSCTPCLKANIERLEEEKQKLLDEIESLTLRLSEEQENKRRMGDRLSHERHQFQRDKEA 617
LR+ LK+ E+L+EE+Q++ D +E +LRL +E + +RM D+L R +FQ+++EA
Sbjct: 436 LRTTVTRLKSQTEKLDEERQRMSDRLEDTSLRLKDEMDLYKRMMDKLRQNRLEFQKEREA 495
Query: 618 TQELIEDLRKQLEHLQLLKLEAEQ-RRGRSSSMGLQEYHSRARESELEQEVRRLKQDNRN 676
TQELIEDLRK+LEHLQ+ KL+ E+ RGRS+S GL E+++RARE ELE EV+RLKQ+N
Sbjct: 496 TQELIEDLRKELEHLQMYKLDCERPGRGRSASSGLGEFNARAREVELEHEVKRLKQENYK 555
Query: 677 LKEQNEELNGQIITLSIQGAKSLFST-AFSESLAAEISSVSRDELMEAIQKQEEINFRLQ 735
L++QN++LNGQI++LS+ AK+LF+ ++SLAAEI + SRDELMEA+++QEEINFRL+
Sbjct: 556 LRDQNDDLNGQILSLSLYEAKNLFAAQTKAQSLAAEIDTASRDELMEALKEQEEINFRLR 615
Query: 736 DYIDRIIVAIMETNPSILEVK 756
Y+D+II+AI++ NPSILE+K
Sbjct: 616 QYMDKIILAILDHNPSILEIK 636
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 76.6 bits (187), Expect = 8e-14
Identities = 75/258 (29%), Positives = 114/258 (44%), Gaps = 18/258 (6%)
Query: 430 KKVARYLHQSGALTMEALEDPSPELMEGPEEDIADKVVFLERRVLELEKDTAATGEQHSR 489
+K+ R L + T E L +PE GP KV L+ L K+ + G Q
Sbjct: 131 QKLGRSLFKLKNQTAEPL---APEPPAGPS-----KVEQLQDETNHLRKELESVGRQLQA 182
Query: 490 LRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELLCKMEREKSIEIENLQTRLQ 549
+ N L EE+L+EQE R E E R Q+E LC+ E + E L+ + +
Sbjct: 183 EVENNQMLSLLNRRQEERLREQEERLREQE-ERLREQEERLCEQEERLREQEERLREQEE 241
Query: 550 QLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESL---TLRLSEEQENKRRMGDRLSH 606
+L E+ LR L ERL E++++L ++ E L RL E++E R +RL
Sbjct: 242 RLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCE 301
Query: 607 ERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARESELEQE 666
+ + + +E E E LR+Q E L EQ + L+E + ++E
Sbjct: 302 QEERLREQEERLCEQEERLREQEERL------CEQEKLPGQERLLEEVEKLLEQERRQEE 355
Query: 667 VRRLKQDNRNLKEQNEEL 684
RL + R L+E E L
Sbjct: 356 QERLLERERLLEEVEELL 373
Score = 66.6 bits (161), Expect = 8e-11
Identities = 67/224 (29%), Positives = 106/224 (47%), Gaps = 25/224 (11%)
Query: 469 LERRVLE-LEKDTAATGEQHSRLRQENLQLVHRANAL---EEQLKEQELRACEMVLEETR 524
L RR E L + EQ RLR++ +L + L EE+L+EQE R CE EE
Sbjct: 193 LNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQ--EERL 250
Query: 525 R--------QKELLCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKANIERLEEEK 576
R Q+E LC+ E + E L + ++L E+ LR L ERL E++
Sbjct: 251 REHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQE 310
Query: 577 QKLLDEIESLTLRLSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLK 636
++L ++ E L EQE + ++L + +R E ++L+E R+Q E +LL+
Sbjct: 311 ERLCEQEERL-----REQEERLCEQEKLPGQ----ERLLEEVEKLLEQERRQEEQERLLE 361
Query: 637 LE--AEQRRGRSSSMGLQEYHSRARESELEQEVRRLKQDNRNLK 678
E E+ L++ R + E QE+ RL++ R L+
Sbjct: 362 RERLLEEVEELLEQERLRQQDERLWQQETLQELERLRELERMLE 405
Score = 59.3 bits (142), Expect = 1e-08
Identities = 56/213 (26%), Positives = 95/213 (44%), Gaps = 17/213 (7%)
Query: 517 EMVLEETRRQKELLCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKANIERLEEEK 576
E + +ET ++ L + R+ E+EN Q + LR L+ ERL E++
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQE 219
Query: 577 QKLLDEIESLTLRLSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLK 636
++L ++ E RL E++E R +RL Q +R +E + L E + E + L+
Sbjct: 220 ERLCEQEE----RLREQEERLREQEERLC---EQEERLREHEERLCEQEERLCEQEERLR 272
Query: 637 LEAEQRRGRSSSMGLQEYHSRARESELEQEVRRLKQDNRNLKEQNEELNGQIITLSIQGA 696
+ E+ + + QE R +E L ++ RL++ L EQ E L Q L Q
Sbjct: 273 EQEERLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQE- 331
Query: 697 KSLFSTAFSESLAAEISSVSRDELMEAIQKQEE 729
E L E+ ++L+E ++QEE
Sbjct: 332 ----KLPGQERLLEEV-----EKLLEQERRQEE 355
>gi|111955162 5-azacytidine induced 1 isoform b [Homo sapiens]
Length = 1044
Score = 73.9 bits (180), Expect = 5e-13
Identities = 77/281 (27%), Positives = 134/281 (47%), Gaps = 27/281 (9%)
Query: 488 SRLRQE--NLQLVHRANALE--EQLKEQELRACEMVLEETRRQKELLCKMEREKSIEIEN 543
+R +QE L+ +H A L+ E+ ++ LR E + E+ R+KE L + ERE++ + +
Sbjct: 717 ARHKQEVRRLKSLHEAELLQSDERASQRCLRQAEELREQLEREKEALGQQERERARQRQR 776
Query: 544 --LQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLRLSEEQENKR-RM 600
L+ QQL+E +S L T L+A E+ EE+++ ++E TL+ E E +
Sbjct: 777 AELEELRQQLEESSSAL---TRALRAEFEKGREEQERR-HQMELNTLKQQLELERQAWEA 832
Query: 601 GDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARE 660
G E R++E +E+ + K++E L + +LEA+ + S E +
Sbjct: 833 GRTRKEEAWLLNREQELREEIRKGRDKEIE-LVIHRLEADMALAKEESEKAAESRIKRLR 891
Query: 661 SELEQEVRRLKQDNRNLKEQNEELNGQI-----ITLSIQGAKSLFSTAFSESLAA-EISS 714
+ E E+ L+Q R L+E+ EL GQ+ L +QG A ++ A E S
Sbjct: 892 DKYEAELSELEQSERKLQERCSELKGQLGEAEGENLRLQGLVRQKERALEDAQAVNEQLS 951
Query: 715 VSRDELMEAIQKQEEINFRLQDYIDRIIVAIMETNPSILEV 755
R L + I+ Q++ DR+ + ET + E+
Sbjct: 952 SERSNLAQVIR---------QEFEDRLAASEEETRQAKAEL 983
Score = 42.0 bits (97), Expect = 0.002
Identities = 81/358 (22%), Positives = 141/358 (39%), Gaps = 73/358 (20%)
Query: 452 PELMEGPEEDIADKVVFLERRVLELE------------------------KDT-AATGEQ 486
PE GP E ++ + R LE+E K+T A Q
Sbjct: 553 PEAGPGPLELGSEVSTSVMRLKLEVEEKKQAMLLLQRALAQQRDLTARRVKETEKALSRQ 612
Query: 487 HSRLRQENLQLVHRANALEEQLKEQE---LRACEMVL----EETRRQKELLCKMEREKSI 539
R R+ + R A +QL E + CE V+ +E +R E + + + + +
Sbjct: 613 LQRQREHYEATIQRHLAFIDQLIEDKKVLSEKCEAVVAELKQEDQRCTERVAQAQAQHEL 672
Query: 540 EIENLQTRLQQLDEENSE--LRSCTPCLK-ANIERLEEEKQKLLDEIESLTLRLSEEQEN 596
EI+ L+ + ++ E + T +K + LE E QKL+ + RL E
Sbjct: 673 EIKKLKELMSATEKARREKWISEKTKKIKEVTVRGLEPEIQKLIARHKQEVRRLKSLHEA 732
Query: 597 KRRMGDRLSHE---------RHQFQRDKEATQEL------------IEDLRKQLEH---- 631
+ D + + R Q +R+KEA + +E+LR+QLE
Sbjct: 733 ELLQSDERASQRCLRQAEELREQLEREKEALGQQERERARQRQRAELEELRQQLEESSSA 792
Query: 632 -LQLLKLEAEQRRGRSSSMGLQEYHSRARESELEQ---EVRRLKQDNRNLKEQNEELNGQ 687
+ L+ E E+ R E ++ ++ ELE+ E R +++ L + +EL +
Sbjct: 793 LTRALRAEFEKGREEQERRHQMELNTLKQQLELERQAWEAGRTRKEEAWLLNREQELREE 852
Query: 688 I-------ITLSIQGAKSLFSTAFSESLAAEISSVS--RDELMEAIQKQEEINFRLQD 736
I I L I ++ + A ES A S + RD+ + + E+ +LQ+
Sbjct: 853 IRKGRDKEIELVIHRLEADMALAKEESEKAAESRIKRLRDKYEAELSELEQSERKLQE 910
Score = 34.3 bits (77), Expect = 0.44
Identities = 44/160 (27%), Positives = 67/160 (41%), Gaps = 20/160 (12%)
Query: 422 SPTKRLSSKKVARY--LHQSGALTMEALEDPSPELMEGPEEDIA-DKVVFLERRVLELEK 478
S KRL K A L QS E + +L E E++ +V + R LE
Sbjct: 885 SRIKRLRDKYEAELSELEQSERKLQERCSELKGQLGEAEGENLRLQGLVRQKERALE--- 941
Query: 479 DTAATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELLCKMEREKS 538
D A EQ S R Q++ + E++L E EETR+ K L ++ +
Sbjct: 942 DAQAVNEQLSSERSNLAQVIRQE--FEDRLAASE--------EETRQAKAELATLQARQQ 991
Query: 539 IEIE----NLQTRLQQLDEENSELRSCTPCLKANIERLEE 574
+E+E ++T L + +E S LR+ + LEE
Sbjct: 992 LELEEVHRRVKTALARKEEAVSSLRTQHEAAVKRADHLEE 1031
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 73.6 bits (179), Expect = 7e-13
Identities = 76/209 (36%), Positives = 87/209 (41%), Gaps = 26/209 (12%)
Query: 6 PASPPGSEPPGPDPEPGGPDGPGAAQLAPGPAELRLGAPVGGP--DPQSPGLDEPA---- 59
PA PPG P GP PG P PGA A GP R GP +P +PG PA
Sbjct: 352 PAGPPG--PVGPAGGPGFPGAPGAKGEA-GPTGARGPEGAQGPRGEPGTPGSPGPAGASG 408
Query: 60 -PGAAADGGARWSAGPAPGLEGGPRDPGPSAPPPRSGPRGQLASPDAPGP-GPRSEAPLP 117
PG GA+ SAG APG+ G P PGP PP GP+G A GP GP+ + P
Sbjct: 409 NPGTDGIPGAKGSAG-APGIAGAPGFPGPRGPP---GPQG------ATGPLGPKGQTGEP 458
Query: 118 ELDPLFSWTEEPEECGPASCPESAPFRLQGSSSSHRARGEVDVFSPFPAPTAGELALEQG 177
+ E GPA P+ AP G ARGE P P GE
Sbjct: 459 GIAGFKGEQGPKGEPGPAG-PQGAP-GPAGEEGKRGARGEPGGVGPIGPP--GERGAPGN 514
Query: 178 PGSPPQPSDLSQTHPLPSEPVGSQEDGPR 206
G P Q L+ P E S GP+
Sbjct: 515 RGFPGQ-DGLAGPKGAPGERGPSGLAGPK 542
Score = 63.5 bits (153), Expect = 7e-10
Identities = 72/246 (29%), Positives = 88/246 (35%), Gaps = 46/246 (18%)
Query: 3 SAPPASPPGSEPPGPDPEPGGPDGPGAAQL-----APGPAELRLGAPVGGPDPQSP-GLD 56
+ PP + PPG D +PG G A APGP P G P PQ P G+
Sbjct: 827 TGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQ-----GPSGAPGPQGPTGVT 881
Query: 57 EPA--------PGAAADGGARWSAGPAPGLEGGPRDPGPSAPPPRSGPRGQLASPDAPG- 107
P PGA GA GP PG G P PGP P + GP+G PG
Sbjct: 882 GPKGARGAQGPPGATGFPGAAGRVGP-PGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGR 940
Query: 108 ---PGPRSEAPLPELDPLFSWTEEPEECGPASCPESAPFRLQGSSSSH------RARGEV 158
PG + A P EP + GP+ P QG + RGE
Sbjct: 941 AGEPGLQGPAGPP------GEKGEPGDDGPSGA--EGPPGPQGLAGQRGIVGLPGQRGER 992
Query: 159 DVFSPFPAPT-------AGELALEQGPGSPPQPSDLSQTHPLPSEPVGSQEDGPRLRAVF 211
F P P+ A + ++GP P P L+ P DGP R
Sbjct: 993 G-FPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGA 1051
Query: 212 DALDGD 217
+ GD
Sbjct: 1052 AGVKGD 1057
Score = 60.8 bits (146), Expect = 4e-09
Identities = 71/212 (33%), Positives = 81/212 (38%), Gaps = 29/212 (13%)
Query: 6 PASPPGSEPP-------GPDPEPGG--PDGPGAAQLAPG----PAELRLGAPVGGPDPQS 52
PA P G+ P G EPGG P GP + APG P + L P G P +
Sbjct: 475 PAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERG 534
Query: 53 P-GLDEPAPGAAADGGARWSAG--PAPGLEGGPRDPGPSAPPPRSGPRGQLASPDAPGP- 108
P GL P GA D G G A GL G P D GP SG G+ P PGP
Sbjct: 535 PSGLAGPK-GANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQ 593
Query: 109 GPRSEAPLPELDPLFSWTEEPEECGPASCPESAPFR-LQGSSSSHRARGEVDVFSPFPAP 167
G R + + EP + G P + R L G A G P PA
Sbjct: 594 GARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAG-----PPGPAG 648
Query: 168 TAGELALEQGPGSPPQPSDLSQTHPLPSEPVG 199
AG E+G P PS Q P P P G
Sbjct: 649 PAG----ERGEQGAPGPSGF-QGLPGPPGPPG 675
Score = 59.3 bits (142), Expect = 1e-08
Identities = 67/205 (32%), Positives = 82/205 (40%), Gaps = 19/205 (9%)
Query: 15 PGPDPEPGGPDGPGAA--QLAPGPA-ELRLGAPVGGPDPQ-SPGLDEPA--PGAAADGGA 68
PGP EPG PGA+ + PGP L P G P + SPG D P GAA G
Sbjct: 998 PGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGD 1057
Query: 69 RWSAGP--APGLEGGPRDPGPSAPPPRSGPRGQLASPDAPGP-GPRSEAPLPELDPLFSW 125
R G APG G P PGP+ P + G RG+ + GP GP +
Sbjct: 1058 RGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGD 1117
Query: 126 TEEPEECGPASCPESAPFR-LQGSSSSHRARGEVDVFSPFPAPTAGELALEQGPGSPPQP 184
E E G F LQG G D + PA +G +GP P P
Sbjct: 1118 KGEAGEPGERGLKGHRGFTGLQGLPGPPGPSG--DQGASGPAGPSG----PRGPPGPVGP 1171
Query: 185 SDLSQTHPLPSEPVGSQEDGPRLRA 209
S + +P P+G GPR R+
Sbjct: 1172 SGKDGANGIPG-PIG--PPGPRGRS 1193
Score = 56.6 bits (135), Expect = 8e-08
Identities = 58/190 (30%), Positives = 65/190 (34%), Gaps = 34/190 (17%)
Query: 2 ASAPPASPPGSEPPGPDPEPG--------GPDGPGAAQLAPGPAELR-----LGAP---- 44
A PP SP + P G + G GP GP A+ GP R G P
Sbjct: 1069 APGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERG 1128
Query: 45 ----------VGGPDPQSPGLDEPAPGAAADGGARWSAGPA--PGLEGGPRDPGPSAPP- 91
G P P P D+ A G A G R GP G +G PGP PP
Sbjct: 1129 LKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPG 1188
Query: 92 --PRSGPRGQLASPDAPGPGPRSEAPLPELDPLFSWTEEPEECGPASCPESAPFRLQGSS 149
RSG G P PGP P P +D P E GP + G
Sbjct: 1189 PRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQYMRADQAAGGL 1248
Query: 150 SSHRARGEVD 159
H A EVD
Sbjct: 1249 RQHDA--EVD 1256
Score = 54.3 bits (129), Expect = 4e-07
Identities = 62/209 (29%), Positives = 75/209 (35%), Gaps = 22/209 (10%)
Query: 1 MASAPPASPPG-SEPPGPDPEPGGPDGPGAAQLAPGPAELRLGAPVGGPDPQSPGLDEPA 59
M P PPG + PGP G P PG ++ GP P G P P D+
Sbjct: 203 MGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVS-GPM-----GPRGPPGPPGKPGDDGE 256
Query: 60 PGAAADGGARWSAGPAPGLEGGPRDPG-PSAPPPRSGPRGQLASPDAPGPGPRSEAPLPE 118
G G R GP G G P PG P R P A +A PG + E+ P
Sbjct: 257 AGKPGKAGERGPPGP-QGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSP- 314
Query: 119 LDPLFSWTEEPEECGPASCPESAPFRLQGSSSSHRARGEVDVFSPFPAPTAGELALEQGP 178
P GP P G + + ARG P PA G + GP
Sbjct: 315 -----GENGSPGPMGPRGLPGER--GRTGPAGAAGARGNDG--QPGPAGPPGPVGPAGGP 365
Query: 179 GSPPQPSDLSQTHPLPSE-PVGSQEDGPR 206
G P P + P + P G+Q GPR
Sbjct: 366 GFPGAPGAKGEAGPTGARGPEGAQ--GPR 392
Score = 53.1 bits (126), Expect = 9e-07
Identities = 57/192 (29%), Positives = 71/192 (36%), Gaps = 20/192 (10%)
Query: 6 PASPPGSEPPGPDPEPGGPDGPGAAQLAPGPAELRLGAPVGGPD----PQSPGLDEPAPG 61
P P S P GP PG P PG A P + P G P +PGL
Sbjct: 230 PGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGH 289
Query: 62 AAADG--GARWSAGPAPGLEGGPRDPGPSAPPPRSGPRGQLASPDAPGPGPRSEAPLPEL 119
G GA+ AG APG++G PG + P GPRG GP + A +
Sbjct: 290 RGYPGLDGAKGEAG-APGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDG 348
Query: 120 DPLFSWTEEPEECGPASCP----------ESAPFRLQGSSSSHRARGEVDV-FSPFPAPT 168
P P GPA P E+ P +G + RGE SP PA
Sbjct: 349 QP--GPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGA 406
Query: 169 AGELALEQGPGS 180
+G + PG+
Sbjct: 407 SGNPGTDGIPGA 418
Score = 52.4 bits (124), Expect = 2e-06
Identities = 68/230 (29%), Positives = 90/230 (39%), Gaps = 42/230 (18%)
Query: 6 PASPPGSE----PPGPDPEPGGPD-----GPGAAQLAPGPAELR--LGAP----VGGPDP 50
P+ PG + PPGP G P GP A PG A + GAP + G D
Sbjct: 577 PSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDG 636
Query: 51 QSPGLDEPAP-GAAADGGARWSAGPAPGLEGGPRDPGPSAPPPRSGPRGQLASPDAPG-P 108
++ P P G A + G + + GP+ G +G P PGP + G +G APG
Sbjct: 637 ETGAAGPPGPAGPAGERGEQGAPGPS-GFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLV 695
Query: 109 GPRSEAPLPELD--------------PLFSWTEEPE-ECGPASCP-ESAPFRLQGSSSSH 152
GPR E P P T+ P+ GPA P P LQG
Sbjct: 696 GPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGER 755
Query: 153 RARGEVDVFSPFPAPTAGELALEQGP-GSPPQPSDLSQTHPL-PSEPVGS 200
A G P G++ E+GP G+P + T P+ P P G+
Sbjct: 756 GAAGIAG-----PKGDRGDVG-EKGPEGAPGKDGGRGLTGPIGPPGPAGA 799
Score = 52.0 bits (123), Expect = 2e-06
Identities = 48/144 (33%), Positives = 53/144 (36%), Gaps = 33/144 (22%)
Query: 6 PASPPGSEPPGPDPEPGGPDGPGAAQLAPGPAELRLGAP--VGGPDPQSP---------- 53
P PPG + P + P G G + APGP R G P G P P P
Sbjct: 118 PKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRG-RDGEPGTPGNPGPPGPPGPPGPPGLG 176
Query: 54 ---------GLDEPAPGA--------AADGGARWSAGP--APGLEGGPRDPGPSAPPPRS 94
G DE A GA G R GP APG +G +PG P S
Sbjct: 177 GNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVS 236
Query: 95 GPRGQLASPDAPG-PGPRSEAPLP 117
GP G P PG PG EA P
Sbjct: 237 GPMGPRGPPGPPGKPGDDGEAGKP 260
Score = 50.4 bits (119), Expect = 6e-06
Identities = 61/215 (28%), Positives = 75/215 (34%), Gaps = 35/215 (16%)
Query: 6 PASPPGSE-PPGPDPEPGGPDGPGAAQLAPGPAELRLGAPVGGPDPQ-SPGLDEP--APG 61
PA PPG++ PPG PG G A ++ P G P GL P PG
Sbjct: 736 PAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPG 795
Query: 62 AAADGGARWSAGP-----APGLEGGPRDPGPSAPPPRSGPRGQLASPDAPG-PGPRSEAP 115
A G + GP + G G P + G + PP GP G P A G PG + E
Sbjct: 796 PAGANGEKGEVGPPGPAGSAGARGAPGERGETGPP---GPAGFAGPPGADGQPGAKGE-- 850
Query: 116 LPELDPLFSWTEEPEECGPASCPESAPFRLQGSSSSHRARGEVDVFSPFPAPTA----GE 171
E + G A P QG S + +G V P A A G
Sbjct: 851 ----------QGEAGQKGDAGAPGP-----QGPSGAPGPQGPTGVTGPKGARGAQGPPGA 895
Query: 172 LALEQGPGSPPQPSDLSQTHPLPSEPVGSQEDGPR 206
G P P P P S +DGP+
Sbjct: 896 TGFPGAAGRVGPPGSNGNPGP-PGPPGPSGKDGPK 929
Score = 49.7 bits (117), Expect = 1e-05
Identities = 58/212 (27%), Positives = 75/212 (35%), Gaps = 41/212 (19%)
Query: 5 PPASPPGSEPPGPDPEPGGPDGPGAAQLAPGPAELRLGAPVGGPDPQSPGLDEP--APGA 62
PP P PG PG PG GP R G P P + GL P PG
Sbjct: 670 PPGPPGEGGKPGDQGVPGEAGAPGLV----GPRGER-GFPGERGSPGAQGLQGPRGLPGT 724
Query: 63 AADGGARWSAGPAPGLEGGPRDPGPSAPPPRSGPRGQLASPDAPGP-GPRSEAPLPELDP 121
G + ++GPA GP PG PP G G+ + GP G R +
Sbjct: 725 PGTDGPKGASGPA-----GP--PGAQGPPGLQGMPGERGAAGIAGPKGDRGDV------- 770
Query: 122 LFSWTEEPEECGPASCPE-------SAPFRLQGSSSSHRARGEVDVFSPFPAPTAGELAL 174
E GP P + P G + ++ +GEV P PA +AG
Sbjct: 771 --------GEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVG--PPGPAGSAGARGA 820
Query: 175 --EQGPGSPPQPSDLSQTHPLPSEPVGSQEDG 204
E+G PP P+ + +P E G
Sbjct: 821 PGERGETGPPGPAGFAGPPGADGQPGAKGEQG 852
Score = 49.3 bits (116), Expect = 1e-05
Identities = 53/196 (27%), Positives = 69/196 (35%), Gaps = 38/196 (19%)
Query: 23 GPDGPGAAQLAPGPAELRLGAPVGGPDPQSPGLDEPAPGAAADGGARWSAGPA-----PG 77
G GP + PG + +G P G P PQ P ++ G D G + + GP PG
Sbjct: 98 GQPGPKGQKGEPGDIKDIVG-PKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPG 156
Query: 78 LEGGPRDPGPSAPPPRSGPRGQLASPDAPGPGPRS--------EAPLPELDPLFSWTEEP 129
G P PGP PP G G A+ A G ++ + P+ + P P
Sbjct: 157 TPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGP-----RGP 211
Query: 130 EECGPASCPESAPFRLQGSSSSHRARGEVDVFSPFPAPTAGELALEQGPGSPPQPSDLSQ 189
GPA P QG + GE V P GP PP P
Sbjct: 212 P--GPAGAPGP-----QGFQGNPGEPGEPGVSGP------------MGPRGPPGPPGKPG 252
Query: 190 THPLPSEPVGSQEDGP 205
+P + E GP
Sbjct: 253 DDGEAGKPGKAGERGP 268
Score = 47.8 bits (112), Expect = 4e-05
Identities = 53/184 (28%), Positives = 64/184 (34%), Gaps = 27/184 (14%)
Query: 6 PASPPG-SEPPGPDPEPGGPDGPGAAQLAPGPAELRLGAPVGGPDPQSPGLDEPAPGAAA 64
P PPG + G E G P G+A P E P G P + PGA
Sbjct: 790 PIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKG 849
Query: 65 DGGARWSAGP--APGLEGGPRDPGPSAPPPRSGPRGQLASPDAPG----PGPRSEAPLPE 118
+ G G APG +G PGP P +GP+G + PG PG P
Sbjct: 850 EQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPG 909
Query: 119 LDPLFSWTEEPEECGPASCPESAPFRLQGSSSSHRARGEVDVFSPFPAPTAGELALEQGP 178
+ GP P + G ARG+ P AGE L QGP
Sbjct: 910 SN---------GNPGPPGPPGPS-----GKDGPKGARGDSG-----PPGRAGEPGL-QGP 949
Query: 179 GSPP 182
PP
Sbjct: 950 AGPP 953
Score = 37.7 bits (86), Expect = 0.040
Identities = 41/173 (23%), Positives = 50/173 (28%), Gaps = 13/173 (7%)
Query: 44 PVGGPDPQSPGLDEPAPGAAADGGARWSAGPAPGLEGGPRDPGPSAPPPRSGPRGQLASP 103
P G P P A G G + G + G PGP P GPRG
Sbjct: 81 PFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDK 140
Query: 104 DAPG-PGPRSEAPLPELDPLFSWTEEPEECGPASCPESAPFRLQGSSSSHRARGEVDVFS 162
G PGPR P P GP + ++ G ++ V
Sbjct: 141 GEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQ 200
Query: 163 -----------PFPAPTAGELALEQGPGSPPQPSDLSQTHPL-PSEPVGSQED 203
P PA G + PG P +P P P P G D
Sbjct: 201 GPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGD 253
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 73.6 bits (179), Expect = 7e-13
Identities = 76/209 (36%), Positives = 87/209 (41%), Gaps = 26/209 (12%)
Query: 6 PASPPGSEPPGPDPEPGGPDGPGAAQLAPGPAELRLGAPVGGP--DPQSPGLDEPA---- 59
PA PPG P GP PG P PGA A GP R GP +P +PG PA
Sbjct: 283 PAGPPG--PVGPAGGPGFPGAPGAKGEA-GPTGARGPEGAQGPRGEPGTPGSPGPAGASG 339
Query: 60 -PGAAADGGARWSAGPAPGLEGGPRDPGPSAPPPRSGPRGQLASPDAPGP-GPRSEAPLP 117
PG GA+ SAG APG+ G P PGP PP GP+G A GP GP+ + P
Sbjct: 340 NPGTDGIPGAKGSAG-APGIAGAPGFPGPRGPP---GPQG------ATGPLGPKGQTGEP 389
Query: 118 ELDPLFSWTEEPEECGPASCPESAPFRLQGSSSSHRARGEVDVFSPFPAPTAGELALEQG 177
+ E GPA P+ AP G ARGE P P GE
Sbjct: 390 GIAGFKGEQGPKGEPGPAG-PQGAP-GPAGEEGKRGARGEPGGVGPIGPP--GERGAPGN 445
Query: 178 PGSPPQPSDLSQTHPLPSEPVGSQEDGPR 206
G P Q L+ P E S GP+
Sbjct: 446 RGFPGQ-DGLAGPKGAPGERGPSGLAGPK 473
Score = 63.5 bits (153), Expect = 7e-10
Identities = 72/246 (29%), Positives = 88/246 (35%), Gaps = 46/246 (18%)
Query: 3 SAPPASPPGSEPPGPDPEPGGPDGPGAAQL-----APGPAELRLGAPVGGPDPQSP-GLD 56
+ PP + PPG D +PG G A APGP P G P PQ P G+
Sbjct: 758 TGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQ-----GPSGAPGPQGPTGVT 812
Query: 57 EPA--------PGAAADGGARWSAGPAPGLEGGPRDPGPSAPPPRSGPRGQLASPDAPG- 107
P PGA GA GP PG G P PGP P + GP+G PG
Sbjct: 813 GPKGARGAQGPPGATGFPGAAGRVGP-PGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGR 871
Query: 108 ---PGPRSEAPLPELDPLFSWTEEPEECGPASCPESAPFRLQGSSSSH------RARGEV 158
PG + A P EP + GP+ P QG + RGE
Sbjct: 872 AGEPGLQGPAGPP------GEKGEPGDDGPSGA--EGPPGPQGLAGQRGIVGLPGQRGER 923
Query: 159 DVFSPFPAPT-------AGELALEQGPGSPPQPSDLSQTHPLPSEPVGSQEDGPRLRAVF 211
F P P+ A + ++GP P P L+ P DGP R
Sbjct: 924 G-FPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGA 982
Query: 212 DALDGD 217
+ GD
Sbjct: 983 AGVKGD 988
Score = 60.8 bits (146), Expect = 4e-09
Identities = 71/212 (33%), Positives = 81/212 (38%), Gaps = 29/212 (13%)
Query: 6 PASPPGSEPP-------GPDPEPGG--PDGPGAAQLAPG----PAELRLGAPVGGPDPQS 52
PA P G+ P G EPGG P GP + APG P + L P G P +
Sbjct: 406 PAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERG 465
Query: 53 P-GLDEPAPGAAADGGARWSAG--PAPGLEGGPRDPGPSAPPPRSGPRGQLASPDAPGP- 108
P GL P GA D G G A GL G P D GP SG G+ P PGP
Sbjct: 466 PSGLAGPK-GANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQ 524
Query: 109 GPRSEAPLPELDPLFSWTEEPEECGPASCPESAPFR-LQGSSSSHRARGEVDVFSPFPAP 167
G R + + EP + G P + R L G A G P PA
Sbjct: 525 GARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAG-----PPGPAG 579
Query: 168 TAGELALEQGPGSPPQPSDLSQTHPLPSEPVG 199
AG E+G P PS Q P P P G
Sbjct: 580 PAG----ERGEQGAPGPSGF-QGLPGPPGPPG 606
Score = 59.3 bits (142), Expect = 1e-08
Identities = 67/205 (32%), Positives = 82/205 (40%), Gaps = 19/205 (9%)
Query: 15 PGPDPEPGGPDGPGAA--QLAPGPA-ELRLGAPVGGPDPQ-SPGLDEPA--PGAAADGGA 68
PGP EPG PGA+ + PGP L P G P + SPG D P GAA G
Sbjct: 929 PGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGD 988
Query: 69 RWSAGP--APGLEGGPRDPGPSAPPPRSGPRGQLASPDAPGP-GPRSEAPLPELDPLFSW 125
R G APG G P PGP+ P + G RG+ + GP GP +
Sbjct: 989 RGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGD 1048
Query: 126 TEEPEECGPASCPESAPFR-LQGSSSSHRARGEVDVFSPFPAPTAGELALEQGPGSPPQP 184
E E G F LQG G D + PA +G +GP P P
Sbjct: 1049 KGEAGEPGERGLKGHRGFTGLQGLPGPPGPSG--DQGASGPAGPSG----PRGPPGPVGP 1102
Query: 185 SDLSQTHPLPSEPVGSQEDGPRLRA 209
S + +P P+G GPR R+
Sbjct: 1103 SGKDGANGIPG-PIG--PPGPRGRS 1124
Score = 56.6 bits (135), Expect = 8e-08
Identities = 58/190 (30%), Positives = 65/190 (34%), Gaps = 34/190 (17%)
Query: 2 ASAPPASPPGSEPPGPDPEPG--------GPDGPGAAQLAPGPAELR-----LGAP---- 44
A PP SP + P G + G GP GP A+ GP R G P
Sbjct: 1000 APGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERG 1059
Query: 45 ----------VGGPDPQSPGLDEPAPGAAADGGARWSAGPA--PGLEGGPRDPGPSAPP- 91
G P P P D+ A G A G R GP G +G PGP PP
Sbjct: 1060 LKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPG 1119
Query: 92 --PRSGPRGQLASPDAPGPGPRSEAPLPELDPLFSWTEEPEECGPASCPESAPFRLQGSS 149
RSG G P PGP P P +D P E GP + G
Sbjct: 1120 PRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQYMRADQAAGGL 1179
Query: 150 SSHRARGEVD 159
H A EVD
Sbjct: 1180 RQHDA--EVD 1187
Score = 54.3 bits (129), Expect = 4e-07
Identities = 62/209 (29%), Positives = 75/209 (35%), Gaps = 22/209 (10%)
Query: 1 MASAPPASPPG-SEPPGPDPEPGGPDGPGAAQLAPGPAELRLGAPVGGPDPQSPGLDEPA 59
M P PPG + PGP G P PG ++ GP P G P P D+
Sbjct: 134 MGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVS-GPM-----GPRGPPGPPGKPGDDGE 187
Query: 60 PGAAADGGARWSAGPAPGLEGGPRDPG-PSAPPPRSGPRGQLASPDAPGPGPRSEAPLPE 118
G G R GP G G P PG P R P A +A PG + E+ P
Sbjct: 188 AGKPGKAGERGPPGP-QGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSP- 245
Query: 119 LDPLFSWTEEPEECGPASCPESAPFRLQGSSSSHRARGEVDVFSPFPAPTAGELALEQGP 178
P GP P G + + ARG P PA G + GP
Sbjct: 246 -----GENGSPGPMGPRGLPGER--GRTGPAGAAGARGNDG--QPGPAGPPGPVGPAGGP 296
Query: 179 GSPPQPSDLSQTHPLPSE-PVGSQEDGPR 206
G P P + P + P G+Q GPR
Sbjct: 297 GFPGAPGAKGEAGPTGARGPEGAQ--GPR 323
Score = 53.5 bits (127), Expect = 7e-07
Identities = 67/239 (28%), Positives = 81/239 (33%), Gaps = 53/239 (22%)
Query: 6 PASPPGSEPPGPDPEPGGPDGPG---AAQLAPGPAELRLGAPVGGPD-PQSPGLDEPAPG 61
P +P PPGP P P GP G G AAQ+A G E GA +G P P PG
Sbjct: 86 PGTPGNPGPPGP-PGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPG 144
Query: 62 AAADGGARWSAGPAPGLEGGPRDP------------GPSAPPPRSGPRGQLASPDAPG-- 107
A G + G +G P +P GP PP + G G+ P G
Sbjct: 145 PAGAPGPQ-------GFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGER 197
Query: 108 --PGPRSEAPLPELDPLFSWTEEPEECGPASCP-------ESAPFRLQGSSSSHRARGEV 158
PGP+ P L P G P E+ ++G S S G
Sbjct: 198 GPPGPQGARGFPGTPGL------PGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSP 251
Query: 159 DVFSP----------FPAPTAGELAL--EQGPGSPPQPSDLSQTHPLPSEPVGSQEDGP 205
P PA AG + GP PP P + P P E GP
Sbjct: 252 GPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGP 310
Score = 53.1 bits (126), Expect = 9e-07
Identities = 57/192 (29%), Positives = 71/192 (36%), Gaps = 20/192 (10%)
Query: 6 PASPPGSEPPGPDPEPGGPDGPGAAQLAPGPAELRLGAPVGGPD----PQSPGLDEPAPG 61
P P S P GP PG P PG A P + P G P +PGL
Sbjct: 161 PGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGH 220
Query: 62 AAADG--GARWSAGPAPGLEGGPRDPGPSAPPPRSGPRGQLASPDAPGPGPRSEAPLPEL 119
G GA+ AG APG++G PG + P GPRG GP + A +
Sbjct: 221 RGYPGLDGAKGEAG-APGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDG 279
Query: 120 DPLFSWTEEPEECGPASCP----------ESAPFRLQGSSSSHRARGEVDV-FSPFPAPT 168
P P GPA P E+ P +G + RGE SP PA
Sbjct: 280 QP--GPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGA 337
Query: 169 AGELALEQGPGS 180
+G + PG+
Sbjct: 338 SGNPGTDGIPGA 349
Score = 52.4 bits (124), Expect = 2e-06
Identities = 68/230 (29%), Positives = 90/230 (39%), Gaps = 42/230 (18%)
Query: 6 PASPPGSE----PPGPDPEPGGPD-----GPGAAQLAPGPAELR--LGAP----VGGPDP 50
P+ PG + PPGP G P GP A PG A + GAP + G D
Sbjct: 508 PSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDG 567
Query: 51 QSPGLDEPAP-GAAADGGARWSAGPAPGLEGGPRDPGPSAPPPRSGPRGQLASPDAPG-P 108
++ P P G A + G + + GP+ G +G P PGP + G +G APG
Sbjct: 568 ETGAAGPPGPAGPAGERGEQGAPGPS-GFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLV 626
Query: 109 GPRSEAPLPELD--------------PLFSWTEEPE-ECGPASCP-ESAPFRLQGSSSSH 152
GPR E P P T+ P+ GPA P P LQG
Sbjct: 627 GPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGER 686
Query: 153 RARGEVDVFSPFPAPTAGELALEQGP-GSPPQPSDLSQTHPL-PSEPVGS 200
A G P G++ E+GP G+P + T P+ P P G+
Sbjct: 687 GAAGIAG-----PKGDRGDVG-EKGPEGAPGKDGGRGLTGPIGPPGPAGA 730
Score = 50.4 bits (119), Expect = 6e-06
Identities = 61/215 (28%), Positives = 75/215 (34%), Gaps = 35/215 (16%)
Query: 6 PASPPGSE-PPGPDPEPGGPDGPGAAQLAPGPAELRLGAPVGGPDPQ-SPGLDEP--APG 61
PA PPG++ PPG PG G A ++ P G P GL P PG
Sbjct: 667 PAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPG 726
Query: 62 AAADGGARWSAGP-----APGLEGGPRDPGPSAPPPRSGPRGQLASPDAPG-PGPRSEAP 115
A G + GP + G G P + G + PP GP G P A G PG + E
Sbjct: 727 PAGANGEKGEVGPPGPAGSAGARGAPGERGETGPP---GPAGFAGPPGADGQPGAKGE-- 781
Query: 116 LPELDPLFSWTEEPEECGPASCPESAPFRLQGSSSSHRARGEVDVFSPFPAPTA----GE 171
E + G A P QG S + +G V P A A G
Sbjct: 782 ----------QGEAGQKGDAGAPGP-----QGPSGAPGPQGPTGVTGPKGARGAQGPPGA 826
Query: 172 LALEQGPGSPPQPSDLSQTHPLPSEPVGSQEDGPR 206
G P P P P S +DGP+
Sbjct: 827 TGFPGAAGRVGPPGSNGNPGP-PGPPGPSGKDGPK 860
Score = 49.7 bits (117), Expect = 1e-05
Identities = 58/212 (27%), Positives = 75/212 (35%), Gaps = 41/212 (19%)
Query: 5 PPASPPGSEPPGPDPEPGGPDGPGAAQLAPGPAELRLGAPVGGPDPQSPGLDEP--APGA 62
PP P PG PG PG GP R G P P + GL P PG
Sbjct: 601 PPGPPGEGGKPGDQGVPGEAGAPGLV----GPRGER-GFPGERGSPGAQGLQGPRGLPGT 655
Query: 63 AADGGARWSAGPAPGLEGGPRDPGPSAPPPRSGPRGQLASPDAPGP-GPRSEAPLPELDP 121
G + ++GPA GP PG PP G G+ + GP G R +
Sbjct: 656 PGTDGPKGASGPA-----GP--PGAQGPPGLQGMPGERGAAGIAGPKGDRGDV------- 701
Query: 122 LFSWTEEPEECGPASCPE-------SAPFRLQGSSSSHRARGEVDVFSPFPAPTAGELAL 174
E GP P + P G + ++ +GEV P PA +AG
Sbjct: 702 --------GEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVG--PPGPAGSAGARGA 751
Query: 175 --EQGPGSPPQPSDLSQTHPLPSEPVGSQEDG 204
E+G PP P+ + +P E G
Sbjct: 752 PGERGETGPPGPAGFAGPPGADGQPGAKGEQG 783
Score = 47.8 bits (112), Expect = 4e-05
Identities = 53/184 (28%), Positives = 64/184 (34%), Gaps = 27/184 (14%)
Query: 6 PASPPG-SEPPGPDPEPGGPDGPGAAQLAPGPAELRLGAPVGGPDPQSPGLDEPAPGAAA 64
P PPG + G E G P G+A P E P G P + PGA
Sbjct: 721 PIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKG 780
Query: 65 DGGARWSAGP--APGLEGGPRDPGPSAPPPRSGPRGQLASPDAPG----PGPRSEAPLPE 118
+ G G APG +G PGP P +GP+G + PG PG P
Sbjct: 781 EQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPG 840
Query: 119 LDPLFSWTEEPEECGPASCPESAPFRLQGSSSSHRARGEVDVFSPFPAPTAGELALEQGP 178
+ GP P + G ARG+ P AGE L QGP
Sbjct: 841 SN---------GNPGPPGPPGPS-----GKDGPKGARGDSG-----PPGRAGEPGL-QGP 880
Query: 179 GSPP 182
PP
Sbjct: 881 AGPP 884
Score = 34.7 bits (78), Expect = 0.34
Identities = 38/162 (23%), Positives = 48/162 (29%), Gaps = 14/162 (8%)
Query: 54 GLDEPAPGAAADGGARWSAGPAPGLEGGPRDPGPSAPPPRSGPRGQLASPDAPGPGPRSE 113
G D PG G G +G P GP+ G RG APGP R
Sbjct: 25 GQDVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDG 84
Query: 114 APLPELDPLFSWTEEPEECGPASCPESAPFRLQGSSSSHRARGEVDVFS----------- 162
P +P P GP + ++ G ++ V
Sbjct: 85 EPGTPGNP--GPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGP 142
Query: 163 PFPAPTAGELALEQGPGSPPQPSDLSQTHPL-PSEPVGSQED 203
P PA G + PG P +P P P P G D
Sbjct: 143 PGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGD 184
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 72.8 bits (177), Expect = 1e-12
Identities = 88/337 (26%), Positives = 165/337 (48%), Gaps = 40/337 (11%)
Query: 438 QSGALTMEALEDPSPELMEGPEEDIADKVVFLERRVLELEKDTAATGEQHSRLRQENLQL 497
Q+ L +E + +++ EE+++ VV ER L E DT + ++ + L Q + ++
Sbjct: 1929 QTEKLCLEKDNENKQKVIVCLEEELS--VVTSERNQLRGELDTMS--KKTTALDQLSEKM 1984
Query: 498 VHRANALEEQLKEQELRACEMVLE-ETRRQKELLCKMEREKSIEIEN---LQTRLQQLDE 553
+ LE + E C V E E + + ELL + + S +++ LQ +LQ L E
Sbjct: 1985 KEKTQELESH--QSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSL-E 2041
Query: 554 ENSELRSCTPC-LKANIERLEEEKQKLLDEIESLTLRLSEEQENKRRMGDRLSH---ERH 609
++S+ S T C L+ I +L +EK+ L+ E ESL RLSE K + L E+
Sbjct: 2042 KDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKG 2101
Query: 610 QFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARESELEQEVRR 669
+F +TQE + LR+ +E L+ +++EA++++ + H + E E+E
Sbjct: 2102 EFALRLSSTQEEVHQLRRGIEKLR-VRIEADEKK---------QLHIAEKLKERERENDS 2151
Query: 670 LKQDNRNLKE--QNEELNGQIITLSIQGAKSLFSTAFSESLAAEISSVSRD------ELM 721
LK NL+ Q E N +++ L + +K A E+L +I ++R +L+
Sbjct: 2152 LKDKVENLERELQMSEENQELVILDAENSK-----AEVETLKTQIEEMARSLKVFELDLV 2206
Query: 722 EAIQKQEEINFRLQDYIDRI--IVAIMETNPSILEVK 756
++E + ++Q+ ++ + ++ + S+LE K
Sbjct: 2207 TLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEK 2243
Score = 53.1 bits (126), Expect = 9e-07
Identities = 75/293 (25%), Positives = 116/293 (39%), Gaps = 31/293 (10%)
Query: 453 ELMEGPEEDIADKVVFLERRVLELEKDTAATGEQHSRLRQENLQLV----HRANALEEQL 508
E E + IA+K+ ER L KD E+ ++ +EN +LV + A E L
Sbjct: 2129 EADEKKQLHIAEKLKERERENDSL-KDKVENLERELQMSEENQELVILDAENSKAEVETL 2187
Query: 509 KEQ------ELRACEMVLEETRRQKELLCKMEREKSIEIENLQTRLQQLDEENSELRSCT 562
K Q L+ E+ L R +KE L K +EK ++ L L E
Sbjct: 2188 KTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAE 2247
Query: 563 PCLKANIERLEEEKQKLLDEIESLTLRLSEEQENKRRMGDRLS---HERHQFQRDKEATQ 619
+K + E Q L E+ L +QE + L E HQ + E +
Sbjct: 2248 IQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLR 2307
Query: 620 ELIE-DLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARESELEQEVRRLKQDNRNLK 678
+E D +KQL LQ LK S R E E E+ R Q++ L+
Sbjct: 2308 ARLEADEKKQLCVLQQLK---------ESEHHADLLKGRVENLERELEIARTNQEHAALE 2358
Query: 679 EQNEELNGQIITLSIQGAKSLFSTAFSESLAAEISSV--SRDELMEAIQKQEE 729
+N + G++ TL AK T L ++ ++ ++ L +QK++E
Sbjct: 2359 AENSK--GEVETLK---AKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQE 2406
Score = 52.0 bits (123), Expect = 2e-06
Identities = 70/300 (23%), Positives = 139/300 (46%), Gaps = 42/300 (14%)
Query: 471 RRVLELEKDTAA----TGEQHSRLRQENLQLVHRANALE-EQLKEQELRACEMVLEETRR 525
+R+ +L++DT+A E S L + +L + +E EQ + QEL+ +LE++ +
Sbjct: 883 QRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLK 942
Query: 526 QKELLCK---MEREKSIEIENLQTR-LQQLDEENSELRSCTPCLKANIERLEEEKQKLLD 581
+ +LL + +E+++ I +L R +++L +EN L+ L +EK L+
Sbjct: 943 ELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLN-------QEKMNLIQ 995
Query: 582 EIESLTLRLSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQ 641
+ ES + E +++ + D+ E+ + E T EDL + K +A Q
Sbjct: 996 KSESFANYIDEREKSISELSDQYKQEKLILLQRCEETGNAYEDLSQ--------KYKAAQ 1047
Query: 642 RRGRSSSMGLQEYHS--RARESELEQEVRRLKQDNRNL-------KEQNEELNGQIITLS 692
+ L E S R++ELEQ ++++ +E+N+ L ++ T
Sbjct: 1048 EKNSKLECLLNECTSLCENRKNELEQLKEAFAKEHQEFLTKLAFAEERNQNLMLELET-- 1105
Query: 693 IQGAKSLFSTAFSESLAAEISSVSRDELM----EAIQKQEEINFRLQDYIDRIIVAIMET 748
+Q A T + +E + + E+M E + Q+E+N LQ+ + ++ +M+T
Sbjct: 1106 VQQALRSEMTDNQNNSKSEAGGL-KQEIMTLKEEQNKMQKEVNDLLQE--NEQLMKVMKT 1162
Score = 45.1 bits (105), Expect = 2e-04
Identities = 61/295 (20%), Positives = 122/295 (41%), Gaps = 35/295 (11%)
Query: 431 KVARYLHQSGALTMEALEDPSPELMEGPEEDIADKVVFLERRVL----ELEKDTAATGEQ 486
++ R +H+ T E E+ + G + +A ++ L + +L++ T E
Sbjct: 2620 ELQREMHEMAQKTAELQEE-----LSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSEL 2674
Query: 487 HSRLRQENLQLVHRANALEEQLKEQELRACEM------VLEETRRQKELLCKMEREKSIE 540
L + V + + E++ E +LR E +L +T +Q E+ + REK
Sbjct: 2675 KKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTS 2734
Query: 541 IEN-LQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLRLSEEQENKRR 599
E L ++ ++D S LKA + LEE K+ +D ++ + +L +E E +
Sbjct: 2735 KEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVN-QLKKENERAQG 2793
Query: 600 MGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRAR 659
L Q + +KE Q+ +L +L+A Q + ++ ++ +
Sbjct: 2794 KMKLLIKSCKQLEEEKEILQK------------ELSQLQAAQEKQKTGTV------MDTK 2835
Query: 660 ESELEQEVRRLKQDNRNLKEQNEELNGQIITLSIQGAKSLFSTAFSESLAAEISS 714
EL E++ LK+ ++ +E + +L I K + E+ A + S
Sbjct: 2836 VDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLETQVAHLCS 2890
Score = 44.3 bits (103), Expect = 4e-04
Identities = 57/261 (21%), Positives = 109/261 (41%), Gaps = 24/261 (9%)
Query: 485 EQHSRLRQENLQLVHRANALE-------EQLKEQELRACEMV--LEETRRQKELLCKMER 535
E+ +LR +L R A E +QLKE E A + +E R+ E+ +
Sbjct: 2294 EEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQE 2353
Query: 536 EKSIEIENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLRLSEEQE 595
++E EN + ++ L + + L+ ++ + EK+ L +E++ R+SE +
Sbjct: 2354 HAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEI 2413
Query: 596 NKRRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYH 655
+ L + + + KE + +E L+ QL+ L R +++ +
Sbjct: 2414 INSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKEL----------NERVAALHNDQEA 2463
Query: 656 SRARESELEQEVRRLKQDNRNLKEQNEELNGQIITL--SIQGAKSLFSTAFSESLAAEIS 713
+A+E L +V L+ + L + +E I L S+ G + L +
Sbjct: 2464 CKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDG-KQKLEKKDE 2522
Query: 714 SVSRDELMEAIQKQEEINFRL 734
+SR L IQ QE++ +L
Sbjct: 2523 EISR--LKNQIQDQEQLVSKL 2541
Score = 40.0 bits (92), Expect = 0.008
Identities = 37/166 (22%), Positives = 76/166 (45%), Gaps = 14/166 (8%)
Query: 548 LQQLDEENSELRSCTPCLKANIERLEEEK-------QKLLDEIESLTLRLSEEQENKRRM 600
L QL +N ELR+ L+ ++ E+E Q+L ++E + L E+++ +
Sbjct: 280 LDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKC 339
Query: 601 GDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARE 660
D L Q+ + L + L+K E L QR+ S+ E + +E
Sbjct: 340 RDELVRTTAQYDQASTKYTALEQKLKKLTEDLSC------QRQNAESARCSLEQKIKEKE 393
Query: 661 SELEQEVRRLKQDNRNLKEQNEELNGQIITLSIQGAKSLFSTAFSE 706
E ++E+ R ++ + L ++ ++ + +T +Q AK++ + +E
Sbjct: 394 KEFQEELSRQQRSFQTLDQECIQMKAR-LTQELQQAKNMHNVLQAE 438
Score = 37.7 bits (86), Expect = 0.040
Identities = 67/315 (21%), Positives = 131/315 (41%), Gaps = 47/315 (14%)
Query: 453 ELMEGPEEDIADKVVFLERRVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQE 512
E + E++++ +V LELEK G ++ + L N L +++++ +
Sbjct: 2462 EACKAKEQNLSSQV-----ECLELEKAQLLQGLDEAK--NNYIVLQSSVNGLIQEVEDGK 2514
Query: 513 LRACEMVLEETRRQKELLCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKANIERL 572
+ E EE R K + E+ S ++ ++ Q E+N ELR+ T L+ I+ L
Sbjct: 2515 QKL-EKKDEEISRLKNQIQDQEQLVS-KLSQVEGEHQLWKEQNLELRNLTVELEQKIQVL 2572
Query: 573 EEEKQKLLDEIESL---------TLRLSE-------EQENKRRMGD-RLSHERHQF-QRD 614
+ + L D +E L L L++ E+ NK + L E H+ Q+
Sbjct: 2573 QSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKT 2632
Query: 615 KEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQ----------------EYHSRA 658
E +EL + + LQLL E + + + + L+ E +
Sbjct: 2633 AELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKV 2692
Query: 659 RESELEQEVRRLKQDNRN---LKEQNEELNGQIITLSIQGAKSLFSTAFSESLAAEISSV 715
RE E ++R + + ++ L + N++ +I T + S S+ L ++
Sbjct: 2693 REEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYR-EKLTSKEECLSSQKLEIDLLKS 2751
Query: 716 SRDELMEAIQKQEEI 730
S++EL +++ +I
Sbjct: 2752 SKEELNNSLKATTQI 2766
Score = 36.6 bits (83), Expect = 0.089
Identities = 49/227 (21%), Positives = 96/227 (42%), Gaps = 27/227 (11%)
Query: 459 EEDIADKVVFLERRVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQL--KEQELRAC 516
E + +++ + R+ E EK + + L N Q E+L KE+ L +
Sbjct: 2689 EGKVREEIAEYQLRLHEAEK------KHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQ 2742
Query: 517 EMVLEETRRQKELLCK--------MEREKSIEIENLQTRLQQLDEENSELRSCTPCLKAN 568
++ ++ + KE L +E K +++NL+ + QL +EN + L +
Sbjct: 2743 KLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKY-VNQLKKENERAQGKMKLLIKS 2801
Query: 569 IERLEEEKQKLLDEIESLTLRLSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQ 628
++LEEEK+ L E+ L E+Q+ M ++ + + KE +E ++ +
Sbjct: 2802 CKQLEEEKEILQKELSQLQAA-QEKQKTGTVMDTKVDELTTEIKELKETLEEKTKEADEY 2860
Query: 629 LEHLQLLKLEAEQRRGRSSSMGLQEYHSRARESELEQEVRRLKQDNR 675
L+ L + E+ + Q H +++S KQD+R
Sbjct: 2861 LDKYCSLLISHEKLEKAKEMLETQVAHLCSQQS---------KQDSR 2898
Score = 35.8 bits (81), Expect = 0.15
Identities = 51/285 (17%), Positives = 118/285 (41%), Gaps = 49/285 (17%)
Query: 460 EDIADKVVFLERRVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMV 519
+ + K LE+++ +L +D + + R +LE+++KE
Sbjct: 351 DQASTKYTALEQKLKKLTEDLSCQRQNAESARC----------SLEQKIKE--------- 391
Query: 520 LEETRRQKELLCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKL 579
+E Q+EL + ++++ E +Q + +L +E + ++ L+A +++L KQ+L
Sbjct: 392 -KEKEFQEELSRQQRSFQTLDQECIQMK-ARLTQELQQAKNMHNVLQAELDKLTSVKQQL 449
Query: 580 LDEIESLTLRLSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEA 639
+ +E +L ++ FQ + EL + + + LLK +
Sbjct: 450 ENNLEEFKQKLCRAEQ--------------AFQASQIKENELRRSMEEMKKENNLLKSHS 495
Query: 640 EQRRGRSSSMGLQEYHSRARESELEQEVRRLKQDNRN----LKEQNEELNGQIITLSIQG 695
EQ+ + + + + ++ + +K N + L++ E++N Q +L+++
Sbjct: 496 EQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEK 555
Query: 696 AKSLFSTAFSESLAAEISSVSRDELMEAIQKQEEINFRLQDYIDR 740
K LA RD + ++K+E +L D + +
Sbjct: 556 LK----------LAVADLEKQRDCSQDLLKKREHHIEQLNDKLSK 590
Score = 33.9 bits (76), Expect = 0.57
Identities = 52/233 (22%), Positives = 98/233 (42%), Gaps = 21/233 (9%)
Query: 503 ALEEQLKEQELRACEMVLEETRRQKELLCKMEREKSIEIENLQTRLQQLDE-------EN 555
ALEE + RA + + +E Q + L K ++++ ++++L+ LQ+ + E
Sbjct: 4 ALEEWKEGLPTRALQKI-QELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEG 62
Query: 556 SELRSCTPCLKANIERLEEEKQKLLDEIE--SLTLRLSEEQENK-----RRMGDRLSHER 608
+ L+ L E LE+ KQK+ E++ + E Q N ++ L +
Sbjct: 63 TNLKRENQRLMEICESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCK 122
Query: 609 HQFQRDKEATQELIEDLR--KQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARE--SELE 664
+ +R ++A Q L + + L Q S L+E +++ E LE
Sbjct: 123 SELERSQQAAQSADVSLNPCNTPQKIFTTPLTPSQYYSGSKYEDLKEKYNKEVEERKRLE 182
Query: 665 QEVRRLKQDNRNLKEQNEELNGQIITLSIQGAKSLFSTAFSESLAAEISSVSR 717
EV+ L+ + +N + I Q + S+FS E + +SS S+
Sbjct: 183 AEVKALQAKKASQTLPQATMNHRDIARH-QASSSVFSWQ-QEKTPSHLSSNSQ 233
Score = 31.6 bits (70), Expect = 2.8
Identities = 53/259 (20%), Positives = 102/259 (39%), Gaps = 26/259 (10%)
Query: 488 SRLRQENLQLVHRANALEE---------QLKEQELRACEMVLEETRRQKELLCKMEREKS 538
+ L++EN +L+ +LE+ Q+KE ++ E L ++Q E L + +
Sbjct: 63 TNLKRENQRLMEICESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCK 122
Query: 539 IEIENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLRLSEEQENKR 598
E+E Q Q D L C K L + + E L + ++E E ++
Sbjct: 123 SELERSQQAAQSAD---VSLNPCNTPQKIFTTPLTPSQYYSGSKYEDLKEKYNKEVEERK 179
Query: 599 RMGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRA 658
R+ + + + K+A+Q L + + H + + +A SS Q+ + +
Sbjct: 180 RLEAEV-----KALQAKKASQTLPQ---ATMNHRDIARHQAS-----SSVFSWQQEKTPS 226
Query: 659 RESELEQEVRRLKQDNRNLKEQNEELNGQIITLSIQGAKSLFSTAFSESLAAEISSVSRD 718
S Q + + + +E+ TL I G + S+ F S + + +
Sbjct: 227 HLSSNSQRTPIRRDFSASYFSGEQEVTPSRSTLQI-GKRDANSSFFDNSSSPHLLDQLKA 285
Query: 719 ELMEAIQKQEEINFRLQDY 737
+ E K E+ RLQ +
Sbjct: 286 QNQELRNKINELELRLQGH 304
>gi|237858621 polyamine modulated factor 1 binding protein 1 isoform
b [Homo sapiens]
Length = 882
Score = 71.2 bits (173), Expect = 3e-12
Identities = 72/290 (24%), Positives = 130/290 (44%), Gaps = 31/290 (10%)
Query: 469 LERRVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMV--------- 519
LE V E ++D + E + Q +Q + N+LEE +++ L A +
Sbjct: 296 LEMTVKEAKQDKSKEAE--CKALQAEVQKLK--NSLEEAKQQERLAAQQAAQCKEEAALA 351
Query: 520 ---LEETRRQKELLCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKANIERLEEEK 576
LE+T+R+ + ++++K+ I+ LQ LQ L +E+S + +E L E
Sbjct: 352 GCHLEDTQRKLQKGLLLDKQKADTIQELQRELQMLQKESSMAEKEQTSNRKRVEELSLEL 411
Query: 577 QKLLDEIESLTLRLSEEQ----ENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHL 632
+ L ++E+ + Q E +M D L +HQ + +L EDL+ E
Sbjct: 412 SEALRKLENSDKEKRQLQKTVAEQDMKMNDMLDRIKHQHREQGSIKCKLEEDLQ---EAT 468
Query: 633 QLLKLEAEQRRGRSSSMGLQEYHSRARESELEQEVRRLKQDNRNLKEQNEELNGQIITLS 692
+LL+ + EQ + L E A E +++ + LK+++R L+E+NE L ++ S
Sbjct: 469 KLLEDKREQLKKSKEHEKLMEGELEALRQEFKKKDKTLKENSRKLEEENENLRAELQCCS 528
Query: 693 IQGAKSLFSTAFSESLAAEISSVSRDELMEAIQKQEEINFRLQDYIDRII 742
Q SL S+ + +L + I Q+E LQ +D+ +
Sbjct: 529 TQLESSLNKYNTSQQVI--------QDLNKEIALQKESLMSLQAQLDKAL 570
Score = 40.4 bits (93), Expect = 0.006
Identities = 63/275 (22%), Positives = 111/275 (40%), Gaps = 26/275 (9%)
Query: 474 LELEKDTAATGEQH---SRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELL 530
L+ + D A E+H + + +E + R +A + Q L V ET+ ++ L
Sbjct: 562 LQAQLDKALQKEKHYLQTTITKEAYDALSRKSAACQDDLTQALEKLNHVTSETKSLQQSL 621
Query: 531 CKMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKANIERLEEEK---QKLLDEIESLT 587
+ + +K+ E + +++ + N+ELR L+ + E E K L+E+
Sbjct: 622 TQTQEKKAQLEEEIIAYEERMKKLNTELRK----LRGFHQESELEVHAFDKKLEEMSCQV 677
Query: 588 LRLSEEQENKRRMGDRLSHERHQFQRDKEATQE-LIEDLRKQ--LEHLQLLKLEAEQRRG 644
L+ ++ +N +M + +FQ + A +E L+ED ++ L + K RG
Sbjct: 678 LQWQKQHQNDLKMLAAKEEQLREFQEEMAALKENLLEDDKEPCCLPQWSVPKDTCRLYRG 737
Query: 645 RSSSMGLQEYHSRARESELEQEVRRLKQDNRNLKEQNEELNGQIITLSIQGAKSLFSTAF 704
M + LEQ ++ K N L Q E I LS G K T
Sbjct: 738 NDQIM-----------TNLEQWAKQQKVANEKLGNQLREQVKYIAKLS--GEKDREPTRA 784
Query: 705 SESLAAEISSVSRDELMEAIQKQEEINFRLQDYID 739
S SS S L + ++ N +L+ I+
Sbjct: 785 SSPNTTRPSSPSHSHLHSVMVHLQQENKKLKKEIE 819
Score = 35.0 bits (79), Expect = 0.26
Identities = 37/156 (23%), Positives = 64/156 (41%), Gaps = 12/156 (7%)
Query: 535 REKSIEIENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLR----- 589
+E + + ++ Q D+ ELR+ C A + E+ KL + S T
Sbjct: 91 QETQKRLSEVWQKVSQQDDLIQELRNKLACSNALVLEREKALIKLQADFASCTATHRYPP 150
Query: 590 -LSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSS 648
SEE E+ +++ L ++ E Q L++DLR +LE + +EQ+R
Sbjct: 151 SSSEECEDIKKILKHLQEQKDSQCLHVEEYQNLVKDLRVELEAV------SEQKRNIMKD 204
Query: 649 MGLQEYHSRARESELEQEVRRLKQDNRNLKEQNEEL 684
M E E + R +D L+ + +EL
Sbjct: 205 MMKLELDLHGLREETSAHIERKDKDITILQCRLQEL 240
>gi|237858619 polyamine modulated factor 1 binding protein 1 isoform
a [Homo sapiens]
Length = 1007
Score = 71.2 bits (173), Expect = 3e-12
Identities = 72/290 (24%), Positives = 130/290 (44%), Gaps = 31/290 (10%)
Query: 469 LERRVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMV--------- 519
LE V E ++D + E + Q +Q + N+LEE +++ L A +
Sbjct: 441 LEMTVKEAKQDKSKEAE--CKALQAEVQKLK--NSLEEAKQQERLAAQQAAQCKEEAALA 496
Query: 520 ---LEETRRQKELLCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKANIERLEEEK 576
LE+T+R+ + ++++K+ I+ LQ LQ L +E+S + +E L E
Sbjct: 497 GCHLEDTQRKLQKGLLLDKQKADTIQELQRELQMLQKESSMAEKEQTSNRKRVEELSLEL 556
Query: 577 QKLLDEIESLTLRLSEEQ----ENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHL 632
+ L ++E+ + Q E +M D L +HQ + +L EDL+ E
Sbjct: 557 SEALRKLENSDKEKRQLQKTVAEQDMKMNDMLDRIKHQHREQGSIKCKLEEDLQ---EAT 613
Query: 633 QLLKLEAEQRRGRSSSMGLQEYHSRARESELEQEVRRLKQDNRNLKEQNEELNGQIITLS 692
+LL+ + EQ + L E A E +++ + LK+++R L+E+NE L ++ S
Sbjct: 614 KLLEDKREQLKKSKEHEKLMEGELEALRQEFKKKDKTLKENSRKLEEENENLRAELQCCS 673
Query: 693 IQGAKSLFSTAFSESLAAEISSVSRDELMEAIQKQEEINFRLQDYIDRII 742
Q SL S+ + +L + I Q+E LQ +D+ +
Sbjct: 674 TQLESSLNKYNTSQQVI--------QDLNKEIALQKESLMSLQAQLDKAL 715
Score = 36.2 bits (82), Expect = 0.12
Identities = 51/243 (20%), Positives = 105/243 (43%), Gaps = 37/243 (15%)
Query: 474 LELEKDTAATGEQH---SRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELL 530
L+ + D A E+H + + +E + R +A + Q L V ET+ ++ L
Sbjct: 707 LQAQLDKALQKEKHYLQTTITKEAYDALSRKSAACQDDLTQALEKLNHVTSETKSLQQSL 766
Query: 531 CKMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKANIERLEEEK---QKLLDEIESLT 587
+ + +K+ E + +++ + N+ELR L+ + E E K L+E+
Sbjct: 767 TQTQEKKAQLEEEIIAYEERMKKLNTELRK----LRGFHQESELEVHAFDKKLEEMSCQV 822
Query: 588 LRLSEEQENKRRMGDRLSHERHQFQRDKEATQE-LIED-------------------LRK 627
L+ ++ +N +M + +FQ + A +E L+ED R
Sbjct: 823 LQWQKQHQNDLKMLAAKEEQLREFQEEMAALKENLLEDDKEPCCLPQWSVPKDTCRLYRG 882
Query: 628 QLEHLQLLKLEAEQRRGRSSSMGLQ-----EYHSR--ARESELEQEVRRLKQDNRNLKEQ 680
+ + L+ A+Q++ + +G Q +Y ++ + L + L+Q+N+ LK++
Sbjct: 883 NDQIMTNLEQWAKQQKVANEKLGNQLREQVKYIAKLSGEKDHLHSVMVHLQQENKKLKKE 942
Query: 681 NEE 683
EE
Sbjct: 943 IEE 945
Score = 35.0 bits (79), Expect = 0.26
Identities = 37/156 (23%), Positives = 64/156 (41%), Gaps = 12/156 (7%)
Query: 535 REKSIEIENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLR----- 589
+E + + ++ Q D+ ELR+ C A + E+ KL + S T
Sbjct: 236 QETQKRLSEVWQKVSQQDDLIQELRNKLACSNALVLEREKALIKLQADFASCTATHRYPP 295
Query: 590 -LSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSS 648
SEE E+ +++ L ++ E Q L++DLR +LE + +EQ+R
Sbjct: 296 SSSEECEDIKKILKHLQEQKDSQCLHVEEYQNLVKDLRVELEAV------SEQKRNIMKD 349
Query: 649 MGLQEYHSRARESELEQEVRRLKQDNRNLKEQNEEL 684
M E E + R +D L+ + +EL
Sbjct: 350 MMKLELDLHGLREETSAHIERKDKDITILQCRLQEL 385
>gi|110347443 TATA element modulatory factor 1 [Homo sapiens]
Length = 1093
Score = 69.7 bits (169), Expect = 9e-12
Identities = 97/429 (22%), Positives = 176/429 (41%), Gaps = 46/429 (10%)
Query: 316 TYSECETFTDEDTSTLVHPELQPEGDADSAGGSAVPSECLDAMEEPDHGALLLLPGRPHP 375
T E ++E TLV P E + + +G SA P C E+PD +L+ P
Sbjct: 369 TVESAEGKSEEVNETLVIPT--EEAEMEESGRSATPVNC----EQPD----ILVSSTPIN 418
Query: 376 HGQSVITVIGGEEHFEDYGEGSEAELSPETLCNGQLGCSDPAFLTPSPTKRLSSKKVARY 435
GQ+V+ + + AE PE L + C FL KR +
Sbjct: 419 EGQTVLDKVAEQ--------CEPAESQPEALSEKEDVCKTVEFLNEKLEKREAQ---LLS 467
Query: 436 LHQSGALTMEALEDPSPELMEGPEED--IADKVVFLERRVLELEKDTAATGEQHSRLRQE 493
L + AL EA ++ E+ EE I+ +R+ E EK ++ ++E
Sbjct: 468 LSKEKALLEEAFDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKE 527
Query: 494 ----NLQLVHRANALE--EQLKEQELRACEMVLEETRRQKELLCKMEREKSIEIENLQTR 547
+L R N+ E + LKE++ + ++ E + K+ L N+ +
Sbjct: 528 IKNIKEELATRLNSSETADLLKEKDEQIRGLMEEGEKLSKQQLHN---------SNIIKK 578
Query: 548 LQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLRLSEEQENKRRMGDRLSHE 607
L+ D+EN + L ++ LEEE Q L ++ + +EN +++ + +
Sbjct: 579 LRAKDKENENM---VAKLNKKVKELEEELQHLKQVLDGKEEVEKQHRENIKKLNSMVERQ 635
Query: 608 RHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARESELEQEV 667
++D Q +++L ++ +Q L++ + S A+E+ L +E+
Sbjct: 636 ----EKDLGRLQVDMDELEEKNRSIQ-AALDSAYKELTDLHKANAAKDSEAQEAALSREM 690
Query: 668 RRLKQDNRNLKEQNEELNGQIITLSIQGAKSLFSTAFSESLAAEISSVSRDELMEAIQKQ 727
+ ++ + L++ EE Q TL+IQ + +E AA R E+ E Q+
Sbjct: 691 KAKEELSAALEKAQEEARQQQETLAIQVGDLRLALQRTEQAAARKEDYLRHEIGELQQRL 750
Query: 728 EEINFRLQD 736
+E R Q+
Sbjct: 751 QEAENRNQE 759
Score = 45.4 bits (106), Expect = 2e-04
Identities = 65/280 (23%), Positives = 108/280 (38%), Gaps = 64/280 (22%)
Query: 453 ELMEGPEE---DIADKVVFLERRVLELEKDTAATGEQHSRLRQENLQL------------ 497
++++G EE + + L V EKD L ++N +
Sbjct: 609 QVLDGKEEVEKQHRENIKKLNSMVERQEKDLGRLQVDMDELEEKNRSIQAALDSAYKELT 668
Query: 498 -VHRANALEE------------QLKEQELRACEMVLEETRRQKELLC------------- 531
+H+ANA ++ + KE+ A E EE R+Q+E L
Sbjct: 669 DLHKANAAKDSEAQEAALSREMKAKEELSAALEKAQEEARQQQETLAIQVGDLRLALQRT 728
Query: 532 -----KMEREKSIEIENLQTRLQQLDEENSEL----RSCTPCLKANIERLEEEKQKLLDE 582
+ E EI LQ RLQ+ + N EL S T L IE L+
Sbjct: 729 EQAAARKEDYLRHEIGELQQRLQEAENRNQELSQSVSSTTRPLLRQIENLQATLGSQTSS 788
Query: 583 IESLTLRLSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQR 642
E L LS+ R+G+ + +R++ AT+EL+ + +Q+ +E++
Sbjct: 789 WEKLEKNLSD------RLGESQTLLAAAVERERAATEELLAN------KIQMSSMESQNS 836
Query: 643 --RGRSSSMGLQEYHSRARESELEQEVRRLKQDNRNLKEQ 680
R +S Q + R +LE E R + + NLK++
Sbjct: 837 LLRQENSRFQAQLESEKNRLCKLEDENNRYQVELENLKDE 876
Score = 40.4 bits (93), Expect = 0.006
Identities = 79/349 (22%), Positives = 142/349 (40%), Gaps = 57/349 (16%)
Query: 424 TKRLSSKKVARYLHQSGALTMEALEDPSPELMEGPEEDIADKVVFLERRVL-ELEKDTAA 482
T++ +++K H+ G L E E ++++ V R +L ++E A
Sbjct: 728 TEQAAARKEDYLRHEIGELQQRLQE------AENRNQELSQSVSSTTRPLLRQIENLQAT 781
Query: 483 TGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELLCKMEREKSIEIE 542
G Q S E L+ L ++L E + V E +ELL + S+E +
Sbjct: 782 LGSQTSSW--EKLE-----KNLSDRLGESQTLLAAAVERERAATEELLANKIQMSSMESQ 834
Query: 543 NLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESL----TLRLSEEQENKR 598
N R +ENS ++ K + +LE+E + E+E+L L E ++ K
Sbjct: 835 NSLLR-----QENSRFQAQLESEKNRLCKLEDENNRYQVELENLKDEYVRTLEETRKEKT 889
Query: 599 RMGDRLSHERHQFQRDKEA---TQELIEDLRKQLEHLQLLKLEAEQRRGRSSSM------ 649
+ +L ER + +++++ TQE I++ + + + + RSSS+
Sbjct: 890 LLNSQLEMERMKVEQERKKAIFTQETIKEKER-----KPFSVSSTPTMSRSSSISGVDMA 944
Query: 650 GLQ-------EYHSR--------ARESELEQEVRRLKQDN--RNLKEQNEELNGQIITLS 692
GLQ E H A S L VR + NL+ Q + G+I L
Sbjct: 945 GLQTSFLSQDESHDHSFGPMPISANGSNLYDAVRMGAGSSIIENLQSQLKLREGEITHLQ 1004
Query: 693 IQ-GAKSLFSTAFSESLAAEISSVSRDELMEAIQKQEEINFRLQDYIDR 740
++ G + +E L + DEL E +++ ++ +L+D R
Sbjct: 1005 LEIGNLEKTRSIMAEELVKLTN--QNDELEEKVKEIPKLRTQLRDLDQR 1051
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 68.9 bits (167), Expect = 2e-11
Identities = 49/237 (20%), Positives = 121/237 (51%), Gaps = 13/237 (5%)
Query: 453 ELMEGPEEDIADKVVFLERRVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQE 512
E M EE + + + + ++ K GEQ +++++ Q+ + EEQ+++QE
Sbjct: 206 EQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQ----EEQMRKQE 261
Query: 513 LRACEMVLEETRRQKELLCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKANIERL 572
+ E E+ R Q+E + K ++E++ + E + +Q+ E+ ++R ++ E++
Sbjct: 262 EQMREQE-EQMREQEEQMLK-QKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQM 319
Query: 573 EEEKQKLLDEIESLTLRLSEEQENKRRM---GDRLSHERHQFQRDKEATQELIEDLRKQL 629
E+++++ + E + + + E K +M +++ + Q Q+ +E ++ E +RKQ
Sbjct: 320 REQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQE 379
Query: 630 EHL----QLLKLEAEQRRGRSSSMGLQEYHSRARESELEQEVRRLKQDNRNLKEQNE 682
E + + ++ + EQ + MG Q+ R +E ++ ++ ++++ ++ EQ E
Sbjct: 380 EQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
Score = 65.9 bits (159), Expect = 1e-10
Identities = 45/219 (20%), Positives = 110/219 (50%), Gaps = 18/219 (8%)
Query: 475 ELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELLCKME 534
+++K GEQ ++R++ Q+ + EEQ+++QE + E+ R+Q+E + + E
Sbjct: 214 QMQKQEEQMGEQEEQMRKQEEQMGEQ----EEQVQKQE-EQVQKQEEQMRKQEEQMREQE 268
Query: 535 REKSIEIENLQTRLQQLD------EENSELRSCTPCLKANIERLEEEKQKLLDEIESLTL 588
+ + E + + +Q + E+ ++R ++ E++ E+++++ ++ E +
Sbjct: 269 EQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGK 328
Query: 589 RLSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSS 648
+ + E K +M + ++ Q + +E E E ++KQ E ++ + EQ R +
Sbjct: 329 QEEQMWEQKEQMWE----QKEQMWKQEEQMGEQEEQMQKQEEQ---VRKQEEQMRKQEEQ 381
Query: 649 MGLQEYHSRARESELEQEVRRLKQDNRNLKEQNEELNGQ 687
M QE R +E ++ ++ ++ + ++EQ E++ Q
Sbjct: 382 MRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQ 420
Score = 62.8 bits (151), Expect = 1e-09
Identities = 44/210 (20%), Positives = 104/210 (49%), Gaps = 11/210 (5%)
Query: 484 GEQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELLCKMEREKSIEIEN 543
GEQ +++++ Q+ + EEQ+++QE + E E+ ++Q+E + K E + + E
Sbjct: 209 GEQEEQMQKQEEQMGEQ----EEQMRKQEEQMGEQE-EQVQKQEEQVQKQEEQMRKQEEQ 263
Query: 544 LQTRLQQLDEENSELRSCTPCLKANIERLEEEKQ--KLLDEIESLTLRLSEEQENKRRMG 601
++ + +Q+ E+ ++ + + E+E+Q + +++ ++ E++E R
Sbjct: 264 MREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQE 323
Query: 602 DRLSHERHQFQRDKEATQELIEDLRKQLEHL----QLLKLEAEQRRGRSSSMGLQEYHSR 657
+++ + Q KE E E + KQ E + + ++ + EQ R + M QE R
Sbjct: 324 EQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMR 383
Query: 658 ARESELEQEVRRLKQDNRNLKEQNEELNGQ 687
+E ++ ++ ++ + + EQ E++ Q
Sbjct: 384 KQEEQMRKQEEQMGEQKEQMGEQKEQMREQ 413
Score = 60.8 bits (146), Expect = 4e-09
Identities = 47/212 (22%), Positives = 103/212 (48%), Gaps = 12/212 (5%)
Query: 485 EQHSRLRQENLQLVHRANAL---EEQLKEQELRACEMVLEETRRQKELLCKMEREKSIEI 541
EQ ++R++ Q+ + + EEQ+ EQE + E+ Q+E + K E + +
Sbjct: 182 EQEGQVREQEGQMGEQEGQMGEQEEQMGEQE-EQMQKQEEQMGEQEEQMRKQEEQMGEQE 240
Query: 542 ENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTL--RLSEEQENKRR 599
E +Q + +Q+ ++ ++R ++ E++ E+++++L + E + E++E R
Sbjct: 241 EQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMRE 300
Query: 600 MGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRAR 659
+++ + Q + +E +E E + KQ E + K EQ + M QE +
Sbjct: 301 QEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQK---EQMWEQKEQMWKQEEQMGEQ 357
Query: 660 ESEL---EQEVRRLKQDNRNLKEQNEELNGQI 688
E ++ E++VR+ ++ R +EQ + Q+
Sbjct: 358 EEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQM 389
Score = 50.1 bits (118), Expect = 8e-06
Identities = 45/204 (22%), Positives = 99/204 (48%), Gaps = 21/204 (10%)
Query: 485 EQHSRLRQENLQLVHRANALEEQ---LKEQELRACEMVLEETRRQKELLCKMEREKSIEI 541
EQ ++R++ Q+ + + EQ ++EQE + E + Q+ + + E + +
Sbjct: 154 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE-GQMGEQEGQMGEQEEQMGEQE 212
Query: 542 ENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLRLSEEQENKRRMG 601
E +Q + +Q+ E+ ++R + + EE+ QK ++++ ++ +++E R
Sbjct: 213 EQMQKQEEQMGEQEEQMRK----QEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQE 268
Query: 602 DRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARES 661
+++ + Q + KE T++ E+ + E EQ R + M QE R +E
Sbjct: 269 EQMREQEEQMLKQKEQTEQ--EEQTGEQE---------EQMREQEEQMREQEEQMREQEE 317
Query: 662 EL-EQEVRRLKQDNRNLKEQNEEL 684
++ EQE + KQ+ + + EQ E++
Sbjct: 318 QMREQEEQMGKQEEQ-MWEQKEQM 340
Score = 49.7 bits (117), Expect = 1e-05
Identities = 50/244 (20%), Positives = 114/244 (46%), Gaps = 18/244 (7%)
Query: 449 DPSPELMEGPEEDIADKVVFLERRVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQ- 507
D P EG + +V E +V E E EQ ++R++ Q+ + + EQ
Sbjct: 44 DKIPLPQEGQVREQEGQVREQEGQVREQEGQVR---EQEGQVREQEGQVREQEGQVREQE 100
Query: 508 --LKEQELRACEMVLEETRRQKELLCKMEREKSIEIENLQTRLQ--QLDEENSELRSCTP 563
++EQE + E + ++ ++ E+E + + Q R Q Q+ E+ ++R
Sbjct: 101 GQVREQEGQVREQEGQVREQEGQV---REQEGQVREQEGQVREQEGQVREQEGQVREQEG 157
Query: 564 CLKANIERLEEEKQKLLDEIESLTLRLSEEQENKRRMGDRLSHERHQFQRDKEATQELIE 623
++ ++ E++ ++ ++ + + + +E + +MG+ + Q +E E E
Sbjct: 158 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGE----QEGQMGEQEEQMGEQEE 213
Query: 624 DLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARESELEQEVRRLKQDNRNLKEQNEE 683
++KQ E + + EQ R + MG QE + +E +++++ ++++ ++EQ E+
Sbjct: 214 QMQKQEEQMGE---QEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQ 270
Query: 684 LNGQ 687
+ Q
Sbjct: 271 MREQ 274
Score = 31.6 bits (70), Expect = 2.8
Identities = 53/250 (21%), Positives = 104/250 (41%), Gaps = 15/250 (6%)
Query: 491 RQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELLCKMEREKSIEIENLQTRLQ- 549
R N +L + L+E+L+ E E+ L KEL K+E +K + Q R Q
Sbjct: 3 RITNEELKEKNAELQEELQLVETEKSEIQLHI----KELKRKLETDKIPLPQEGQVREQE 58
Query: 550 -QLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLRLSEEQENKRRMGDRLSHER 608
Q+ E+ ++R ++ ++ E++ ++ ++ + + + +E + ++ ++ R
Sbjct: 59 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 118
Query: 609 HQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARESEL---EQ 665
Q + +E ++ E + E ++ + Q R + + QE R +E ++ E
Sbjct: 119 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 178
Query: 666 EVRRLKQDNRNLKEQNEELNGQIITLSIQGAKSLFSTAFSESLAAEISSVSR------DE 719
+VR + R + Q E GQ+ Q + E E R E
Sbjct: 179 QVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGE 238
Query: 720 LMEAIQKQEE 729
E +QKQEE
Sbjct: 239 QEEQVQKQEE 248
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 68.2 bits (165), Expect = 3e-11
Identities = 69/213 (32%), Positives = 83/213 (38%), Gaps = 36/213 (16%)
Query: 5 PPASPPGSEPPGPDPEPGGPDGPGAAQLAPGPAELRLGAP--VGGPDPQSPGLDEPAPGA 62
PP + PPGP P P G +G + GPA G P VG P P P ++ +PGA
Sbjct: 885 PPGPSGNAGPPGP-PGPAGKEGGKGPRGETGPA----GRPGEVGPPGPPGPAGEKGSPGA 939
Query: 63 AADGGARWSAGPAP--------------GLEGGPRDPGPSAPPPRSGPRGQLASPDAPGP 108
GA + GP G G P PGPS P + GP G PGP
Sbjct: 940 DGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGP 999
Query: 109 -GPRSEAPLPELDPLFSWTEEPEECGPASCPESAPFRLQGSSSSHRARGEVDVFSPFPAP 167
GP A P E E P + E +P R GS + RGE P AP
Sbjct: 1000 MGPPGLAGPP--------GESGREGAPGA--EGSPGR-DGSPGAKGDRGETGPAGPPGAP 1048
Query: 168 TAGELALEQGPGSPPQPSDLSQTHPL-PSEPVG 199
A GP + D +T P P+ PVG
Sbjct: 1049 GAPGAPGPVGPAG--KSGDRGETGPAGPAGPVG 1079
Score = 62.4 bits (150), Expect = 2e-09
Identities = 78/236 (33%), Positives = 87/236 (36%), Gaps = 36/236 (15%)
Query: 6 PASPPGSEPPGPDPEPGGPDGPG--AAQLAPGPAELRLGAPVGGPDPQSPGLDEPAPGAA 63
P PPG P G EPG P G A+ PG PVG P P +E GA
Sbjct: 423 PGGPPG--PKGNSGEPGAPGSKGDTGAKGEPG--------PVGVQGPPGPAGEEGKRGAR 472
Query: 64 ADGGARWSAGPAPGLEGGPRD---PGPSAPPPRSGPRGQLASPDAPGP-------GPRSE 113
+ G GP PG GGP PG GP G+ SP GP G E
Sbjct: 473 GEPGPTGLPGP-PGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGE 531
Query: 114 APLPELDPLFSWTEEPEECGPASCPESA-PFRLQGSSSSHRARGEVDVFS-PFPAPTAGE 171
A LP L P G P A G ARG+ V P P AGE
Sbjct: 532 AGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGE 591
Query: 172 --LALEQG-PGSP----PQPSD---LSQTHPLPSEPVGSQ-EDGPRLRAVFDALDG 216
A E+G PG P P D +Q P P+ P G + E GP F L G
Sbjct: 592 PGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPG 647
Score = 62.0 bits (149), Expect = 2e-09
Identities = 63/183 (34%), Positives = 71/183 (38%), Gaps = 32/183 (17%)
Query: 5 PPASPPGSEPPGPDPEPGGPDGPGAAQL-----APGPAELRLGAPVGGPDPQSPGLDEPA 59
PP + PPG D +PG PG A PGPA P G P P + A
Sbjct: 807 PPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPA-----GPAGPPGPIG---NVGA 858
Query: 60 PGAAADGGARWSAGPAPGLEGGPRDPGPSAPPPRSGPRGQLASPDAPGPGPR--SEAPLP 117
PGA GAR SAGP PG G P G PP GP G P PGP + + P
Sbjct: 859 PGAK---GARGSAGP-PGATGFPGAAGRVGPP---GPSGNAGPPGPPGPAGKEGGKGPRG 911
Query: 118 ELDPLFSWTEEPEECGPASCPESAPFRLQGSSSSHRARGEVDV-FSPFPAPTAGELALEQ 176
E P P E GP P A G S A G +P P AG+ +
Sbjct: 912 ETGP----AGRPGEVGPPGPPGPA-----GEKGSPGADGPAGAPGTPGPQGIAGQRGVVG 962
Query: 177 GPG 179
PG
Sbjct: 963 LPG 965
Score = 61.6 bits (148), Expect = 3e-09
Identities = 66/192 (34%), Positives = 74/192 (38%), Gaps = 26/192 (13%)
Query: 15 PGPDPEPGGPDG---PGAAQLA--PGPAELRLGAPVGGPDPQSPGLDEPAPGAAADGGAR 69
PGP E GGP PGA +A GPA R G P P P + +PG A G
Sbjct: 481 PGPPGERGGPGSRGFPGADGVAGPKGPAGER-----GSPGPAGP---KGSPGEAGRPGEA 532
Query: 70 WSAGPAPGLEGGPRDPGPSAPPPRSGPRGQLASPDAPG-PGPRSEAPLPELDPLFSWTEE 128
G A GL G P PGP GP GQ P PG PG R +A + E
Sbjct: 533 GLPG-AKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGE 591
Query: 129 PEECGPASCP-ESAPFRLQGSSSSHRARGEVDVFSPFPAPTAGELALEQGPGSPPQPSDL 187
P + G P G A+G P PA AGE EQGP P L
Sbjct: 592 PGKAGERGVPGPPGAVGPAGKDGEAGAQG-----PPGPAGPAGERG-EQGPAGSPGFQGL 645
Query: 188 SQTHPLPSEPVG 199
P P+ P G
Sbjct: 646 ----PGPAGPPG 653
Score = 61.6 bits (148), Expect = 3e-09
Identities = 65/209 (31%), Positives = 83/209 (39%), Gaps = 23/209 (11%)
Query: 6 PASPPGSE-PPGPDPEPG--GPDGPGAAQLAPG-PAELRLGAPVGGPDPQSPGLDEPAPG 61
PA PPG PG PG G GP A+ G P E + P G P+ G
Sbjct: 648 PAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDG 707
Query: 62 AAADGGARWSAGP--APGLEGGPRDPGPSAPPPRSGPRGQLASPDAPGPGPRSEAPLPEL 119
A D GA + G APGL+G P + G + P GP+G D GP+ P
Sbjct: 708 AKGDAGAPGAPGSQGAPGLQGMPGERGAAGLP---GPKG-----DRGDAGPKGADGSPGK 759
Query: 120 DPLFSWTEEPEECGPASCP----ESAPFRLQGSSSSHRARGE-VDVFSPFPAPTAGELAL 174
D + T GPA P ES P G + + A G+ + P PA AG
Sbjct: 760 DGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGA 819
Query: 175 EQGPGSPPQPSDLSQT----HPLPSEPVG 199
+ PG+ +P D P P+ P G
Sbjct: 820 DGQPGAKGEPGDAGAKGDAGPPGPAGPAG 848
Score = 59.7 bits (143), Expect = 1e-08
Identities = 67/221 (30%), Positives = 82/221 (37%), Gaps = 41/221 (18%)
Query: 9 PPGSE-PPGPDPEPG-----GPDGPGAAQLAPGPAELRLGAP--VGGPDPQSPGLDEPAP 60
PPG+ P G D E G GP GP + GPA G+P G P P P + P
Sbjct: 603 PPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPA----GSPGFQGLPGPAGPPGEAGKP 658
Query: 61 GAAADGGARWSAGP--APGLEGGPRDPGPSAPPPRSGPRGQLASP-------DAPGPGPR 111
G G + GP A G G P + G PP +GPRG +P DA PG
Sbjct: 659 GEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAP 718
Query: 112 SEAPLPELDPLFSWTEEPEECGPASCP-------ESAPFRLQGSSSSHRARGEV-DVFSP 163
P L + P E G A P ++ P GS RG + P
Sbjct: 719 GSQGAPGLQGM------PGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPP 772
Query: 164 FPAPTAGELALEQGPGSPPQPSDL-----SQTHPLPSEPVG 199
PA G+ E GP P P+ + P P P G
Sbjct: 773 GPAGAPGDKG-ESGPSGPAGPTGARGAPGDRGEPGPPGPAG 812
Score = 58.5 bits (140), Expect = 2e-08
Identities = 67/216 (31%), Positives = 81/216 (37%), Gaps = 49/216 (22%)
Query: 5 PPASPPGSEPPGPDPEPG--GPDGPGAAQLAPGPA-----ELRLGAP-----VGGPDPQS 52
PP +P GP EPG G GP + PGP + G P G P PQ
Sbjct: 192 PPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQG 251
Query: 53 ----------PGLDEPAPGAAADGGARWSAGPAPGLEGGPRDPGPSAPPPRSGPR---GQ 99
PG+ + G + GA+ AGPA G +G P PG + P + GPR G+
Sbjct: 252 ARGLPGTAGLPGM-KGHRGFSGLDGAKGDAGPA-GPKGEPGSPGENGAPGQMGPRGLPGE 309
Query: 100 LASPDAPGP-GPRSEAPLPELDPLFSWTEEPEECGPASCP----------ESAPFRLQGS 148
P APGP G R D P GPA P E+ P +GS
Sbjct: 310 RGRPGAPGPAGARGN------DGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGS 363
Query: 149 SSSHRARGEVDVFSPFPAPTAGELALEQGPGSPPQP 184
RGE P P AG PG+ QP
Sbjct: 364 EGPQGVRGE-----PGPPGPAGAAGPAGNPGADGQP 394
Score = 56.6 bits (135), Expect = 8e-08
Identities = 58/185 (31%), Positives = 68/185 (36%), Gaps = 26/185 (14%)
Query: 6 PASPPG-SEPPGPDPE--PGGPDGPGAAQLAPGPAELRLGAPVGGPDPQSPGLDEPAPGA 62
P PPG + PG E P GP GP A+ APG G P P P PGA
Sbjct: 768 PIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDR--------GEPGPPGPAGFAGPPGA 819
Query: 63 AADGGARWSAGPAPGLEGGPRDPGPSAPPPRSGPRGQLASPDAPG-PGPRSEAPLPELDP 121
GA+ G A G D GP P +GP G + + APG G R A P
Sbjct: 820 DGQPGAKGEPGDA----GAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATG 875
Query: 122 LFSWTEEPEECGPA-SCPESAPFRLQGSSSSHRARGEVDVFSPFPAPTAGELALEQGPGS 180
GP+ + P G RGE PA GE+ GP
Sbjct: 876 FPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETG-----PAGRPGEV----GPPG 926
Query: 181 PPQPS 185
PP P+
Sbjct: 927 PPGPA 931
Score = 55.5 bits (132), Expect = 2e-07
Identities = 70/230 (30%), Positives = 81/230 (35%), Gaps = 60/230 (26%)
Query: 2 ASAP--PASPPGSEPPGPDPEPG-----------GPDGPGAAQLAPGPAELR-------- 40
AS P P PPG PPG + + G GP GP A+ PG A L
Sbjct: 213 ASGPMGPRGPPG--PPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGF 270
Query: 41 --LGAPVGGPDPQSPGLDEPAPGAAADGGARWSAGPA--PGLEGGPRDPGP--------- 87
L G P P + PG+ + GA GP PG G P PGP
Sbjct: 271 SGLDGAKGDAGPAGP---KGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGA 327
Query: 88 ---SAPPPRSGPRGQLASPDAPG-------PGPR-SEAPLPELDPLFSWTEEPEECGPAS 136
+ PP +GP G P A G GPR SE P EP GPA
Sbjct: 328 TGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQ-------GVRGEPGPPGPAG 380
Query: 137 C--PESAPFRLQGSSSSHRARGEVDVFSPFPAPTAGELALEQGPGSPPQP 184
P P G + A G + P A + QGPG PP P
Sbjct: 381 AAGPAGNP-GADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGP 429
Score = 55.5 bits (132), Expect = 2e-07
Identities = 72/232 (31%), Positives = 85/232 (36%), Gaps = 66/232 (28%)
Query: 7 ASPPG-SEPPGPDPEPG--------GPDGPGAAQLAPGPAELRLGAPVGGPDPQSP-GLD 56
A PPG + P GP PG GP GP ++ GP +R G P P P G
Sbjct: 331 AGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSE---GPQGVR-----GEPGPPGPAGAA 382
Query: 57 EPAPGAAADG--GARWSAGPAPGLEGGPRDPG---------PSAPPPRSGPRGQLASPDA 105
PA ADG GA+ + G APG+ G P PG P PP GP+G P A
Sbjct: 383 GPAGNPGADGQPGAKGANG-APGIAGAPGFPGARGPSGPQGPGGPP---GPKGNSGEPGA 438
Query: 106 PGPGPRSEAPLPELDPLFSWTEEPEECGPASCPESAPFRLQGSSSSHRARGEVDVFSPFP 165
PG + A EP G P A G ARGE P P
Sbjct: 439 PGSKGDTGA-----------KGEPGPVGVQGPPGPA-----GEEGKRGARGE-----PGP 477
Query: 166 APTAGELALEQGPGS-----------PPQPSDLSQTHPLPSEPVGSQEDGPR 206
G GPGS P P+ + P P+ P GS + R
Sbjct: 478 TGLPGPPGERGGPGSRGFPGADGVAGPKGPAG-ERGSPGPAGPKGSPGEAGR 528
Score = 53.9 bits (128), Expect = 5e-07
Identities = 51/135 (37%), Positives = 55/135 (40%), Gaps = 33/135 (24%)
Query: 9 PPGSEPPGPDPEPGGPDGPGAAQLA-----PGP----AELRLGAPVGGPDPQSPGLDEPA 59
PPG P G D PG P PGA A PGP E G P P PG PA
Sbjct: 555 PPG--PAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGP--PGAVGPA 610
Query: 60 -----------PGAAADGGARWSAGPA--PGLEGGPRDPGPSAPPPRSGPRGQLASP--- 103
PG A G R GPA PG +G PGP+ PP +G G+ P
Sbjct: 611 GKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGL---PGPAGPPGEAGKPGEQGVPGDL 667
Query: 104 DAPGP-GPRSEAPLP 117
APGP G R E P
Sbjct: 668 GAPGPSGARGERGFP 682
Score = 53.9 bits (128), Expect = 5e-07
Identities = 44/123 (35%), Positives = 51/123 (41%), Gaps = 20/123 (16%)
Query: 6 PASPPGSEPPGPDPEPGGPDGPGAAQLAPGPAELRLGAPVG-----GP-DPQSPGLDEPA 59
PA PPG+ P P GP G + GPA PVG GP PQ P D+
Sbjct: 1041 PAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGP--AGPVGPVGARGPAGPQGPRGDKGE 1098
Query: 60 PGAAADGGARWSAGPA-----PGLEGGPRDPGPSAPPPRSGPRGQLASPDAPG------- 107
G D G + G + PG G P + GPS +GPRG S APG
Sbjct: 1099 TGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGL 1158
Query: 108 PGP 110
PGP
Sbjct: 1159 PGP 1161
Score = 52.4 bits (124), Expect = 2e-06
Identities = 73/238 (30%), Positives = 82/238 (34%), Gaps = 50/238 (21%)
Query: 6 PASPPGSEPP---------GP--DPEPGGPDGPGAAQLAPG-PAELRLGAPVGGPDPQSP 53
P P GSE P GP D P GP GP G P + L P G P P P
Sbjct: 93 PVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGP 152
Query: 54 -------------GLDEPA------PGAAADGGARWSAGP--APGLEGGPRDPGPSAPPP 92
G DE + PG G R GP APG +G PG P
Sbjct: 153 PGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPG 212
Query: 93 RSGPRGQLASPDAPGP-GPRSEAPLPELDPLFSWTEEPEECGPASCPESAPFRLQGSSSS 151
SGP G P PG G EA P P E GP P+ A L G++
Sbjct: 213 ASGPMGPRGPPGPPGKNGDDGEAGKP---------GRPGERGPPG-PQGAR-GLPGTAGL 261
Query: 152 HRARGEVDVFSPFPAP--TAGELALEQGPGSPPQPSDLSQTHP--LPSEPVGSQEDGP 205
+G FS AG + PGSP + Q P LP E GP
Sbjct: 262 PGMKGHRG-FSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGP 318
Score = 52.4 bits (124), Expect = 2e-06
Identities = 66/227 (29%), Positives = 77/227 (33%), Gaps = 35/227 (15%)
Query: 6 PASPPGSE-PPGPDPE------PGGPDGPGAAQLAPGPAELRLGAPVGGPDPQSPGLDEP 58
PA P G+ PG D PG P GA L P E G + +
Sbjct: 693 PAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKG 752
Query: 59 APGAAADGGARWSAGP--APGLEGGPRDPGPSAPPPRSGPRGQLASPDAPG----PGPRS 112
A G+ G R GP PG G P D G S P +GP G +P G PGP
Sbjct: 753 ADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAG 812
Query: 113 EAPLPELDPLFSWTEEPEE------------CGPASCPESAPFRLQGSSSSHRARGEVDV 160
A P D EP + GPA P P G+ + ARG
Sbjct: 813 FAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPP--GPIGNVGAPGAKGARGSAG- 869
Query: 161 FSPFPAPTAGELALEQGPGSPPQPSDLSQTHPLPSEPVGSQ-EDGPR 206
P A G PP PS + P P P G + GPR
Sbjct: 870 -----PPGATGFPGAAGRVGPPGPSG-NAGPPGPPGPAGKEGGKGPR 910
Score = 50.1 bits (118), Expect = 8e-06
Identities = 40/104 (38%), Positives = 44/104 (42%), Gaps = 21/104 (20%)
Query: 9 PPGSE-PPGPDPEPGGPDGPGAAQLAPGPAELRLGAPVGGPDPQSPGLDEPAPGAAADGG 67
PPG PPG GP G + APG SPG D +PGA D G
Sbjct: 996 PPGPMGPPGL----AGPPGESGREGAPGA-------------EGSPGRD-GSPGAKGDRG 1037
Query: 68 ARWSAGPAPGLEGGPRDPGPSAPPPRSGPRGQLASPDAPGP-GP 110
AGP PG G P PGP P +SG RG+ GP GP
Sbjct: 1038 ETGPAGP-PGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGP 1080
Score = 48.5 bits (114), Expect = 2e-05
Identities = 46/135 (34%), Positives = 55/135 (40%), Gaps = 10/135 (7%)
Query: 4 APPASPPGSEPPGPDPEPGGPDGPGAAQLAPGPAELRLGAPVGGPD--PQSPGLDEP--A 59
A P P G+ P P G G Q G R + + GP P SPG P A
Sbjct: 1075 AGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGA 1134
Query: 60 PGAAADGGARWSAGPAPGLEGGPRDPGPSAPPP---RSGPRGQLASPDAPGPGPRSEAPL 116
G A G SAG APG +G PGP PP R+G G + P PGP P
Sbjct: 1135 SGPAGPRGPPGSAG-APGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPS 1193
Query: 117 PELDPLFSWTEEPEE 131
D FS+ +P +
Sbjct: 1194 AGFD--FSFLPQPPQ 1206
Score = 47.4 bits (111), Expect = 5e-05
Identities = 71/234 (30%), Positives = 81/234 (34%), Gaps = 39/234 (16%)
Query: 5 PP--ASPPGSE----PPGPDPEPGGPDGPGAA--QLAPGPAELRLGAPVGGPD-PQSPGL 55
PP A PPG PG + PG PGA + GPA P G P P +PG
Sbjct: 1002 PPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPA-----GPPGAPGAPGAPGP 1056
Query: 56 DEPAPGAAADGGARWSAGPAPGLEGGPRDP-GPSAPPPRSGPRGQLASPDAPGP-GPRSE 113
PA G + D G AGPA GP P G P GPRG G G +
Sbjct: 1057 VGPA-GKSGDRGETGPAGPA-----GPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGH 1110
Query: 114 APLPELDPLFSWTEEPEECGPASCPESAPFRLQGSSSSHRARGEVDVFSPFPAP------ 167
L P E GP+ S P +G S A G+ D + P P
Sbjct: 1111 RGFSGLQGPPGPPGSPGEQGPSGA--SGPAGPRGPPGSAGAPGK-DGLNGLPGPIGPPGP 1167
Query: 168 -----TAGELALEQGPGSPPQPSDLSQTHP---LPSEPVGSQEDGPRLRAVFDA 213
AG + PG P P S LP P DG R DA
Sbjct: 1168 RGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQPPQEKAHDGGRYYRADDA 1221
Score = 37.7 bits (86), Expect = 0.040
Identities = 43/150 (28%), Positives = 50/150 (33%), Gaps = 34/150 (22%)
Query: 65 DGGARWSAGPAPGLEG-----GPRDP-GPSAPPPRSGPRGQLASPDAPGP-GPRSEAPLP 117
DG + G+EG GPR P GP+ PP R G GQ P PGP GP L
Sbjct: 97 DGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLG 156
Query: 118 -ELDPLFSWTEEPEECGPASCPESAPFRLQGSSSSHRARGEVDVFSPFPAPTAGELALEQ 176
P S+ + + G S P G + P P
Sbjct: 157 GNFAPQLSYGYDEKSTGGISVP-----------------GPMGPSGPRGLP--------- 190
Query: 177 GPGSPPQPSDLSQTHPLPSEPVGSQEDGPR 206
GP P P P EP S GPR
Sbjct: 191 GPPGAPGPQGFQGPPGEPGEPGASGPMGPR 220
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 67.8 bits (164), Expect = 4e-11
Identities = 75/318 (23%), Positives = 145/318 (45%), Gaps = 47/318 (14%)
Query: 453 ELMEGPEEDIADKVVFL-ERRVLELEKDTAATGEQHSRLR-----------------QEN 494
EL E P++ + +V L R+L+LE + + + LR +EN
Sbjct: 441 ELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKEN 500
Query: 495 LQLVHRANALEEQL--KEQELRACEMVLEETRRQKELLCKMEREKSIEI--ENLQTRLQQ 550
+L + LE ++ ++Q L+ C+ + ++ ++K L EK+IE EN + +++
Sbjct: 501 QRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQL-----EKTIETLRENSERQIKI 555
Query: 551 LDEENSELRSCTPCLK--------ANIERLEEEKQKLLDEIESLTLRLSEEQENKRRMGD 602
L++EN L L+ A ++ +E+E + L + I+ + +LS+ + KR++
Sbjct: 556 LEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKK 615
Query: 603 RLSHERHQFQRDKEATQELIEDLRKQLEHLQL----LKLEAEQRRGRSSSMGLQEYHSRA 658
L H + + +R +E EL L K+ E LQ LK+ E+ E +R
Sbjct: 616 ELEHYKEKGERAEELENEL-HHLEKENELLQKKITNLKITCEKIEALEQENSELERENRK 674
Query: 659 RESELEQ------EVRRLKQDNRNLKEQNEELNGQIITLSIQGAKSLFSTAFSESLAAEI 712
+ L+ ++ L+++N L E+N EL + +L K ++ L +E
Sbjct: 675 LKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEK 734
Query: 713 SSVSRD-ELMEAIQKQEE 729
+ + EL++A K+ E
Sbjct: 735 EQLKKGLELLKASFKKTE 752
Score = 58.5 bits (140), Expect = 2e-08
Identities = 71/313 (22%), Positives = 134/313 (42%), Gaps = 36/313 (11%)
Query: 455 MEGPEEDIADKVVFLERRVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQELR 514
+E ++ +++ L+R+ + L++ Q+++L+ EN L ++ +L Q + ++
Sbjct: 1072 LETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQ 1131
Query: 515 AC------EMVLEETRRQKEL---LCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCL 565
E V++E K L L K + + E + + L ++ L+S L
Sbjct: 1132 QSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNL 1191
Query: 566 KANIERLEEEKQKLLDE---IESLTLRLSEEQEN---------------KRRMG--DRLS 605
+ LE+ +LL + +E L L EQE K+ G DRL+
Sbjct: 1192 EVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLN 1251
Query: 606 HERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRA--RESEL 663
H Q ++ E Q ++L+ L + +L EQ R + L+E + + ++L
Sbjct: 1252 HTYSQLLKETEVLQTDHKNLKSLLNNSKL-----EQTRLEAEFSKLKEQYQQLDITSTKL 1306
Query: 664 EQEVRRLKQDNRNLKEQNEELNGQIITLSIQGAKSLFSTAFSESLAAEISSVSRDELMEA 723
+ L Q NL+E+N L QI TL +Q L S+ L D+L E
Sbjct: 1307 NNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNEL 1366
Query: 724 IQKQEEINFRLQD 736
+++E++ ++ D
Sbjct: 1367 RRQKEKLEEKIMD 1379
Score = 52.4 bits (124), Expect = 2e-06
Identities = 62/264 (23%), Positives = 112/264 (42%), Gaps = 34/264 (12%)
Query: 427 LSSKKVARYLHQSGALTMEALEDPSPELME--GPEEDIADKVVFLERRVLELEKDTAATG 484
+S + H++ + LED +L++ G ED+ + + ++L K+
Sbjct: 1178 ISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVA 1237
Query: 485 EQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELLCKMEREKS---IEI 541
++ +L EN +L H + L L+ E++ + + K LL + E++ E
Sbjct: 1238 AEYKKLCGENDRLNHTYSQL--------LKETEVLQTDHKNLKSLLNNSKLEQTRLEAEF 1289
Query: 542 ENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLRLSEEQENKRRMG 601
L+ + QQLD +++L + L LEEE + LLD+I++L L+ E
Sbjct: 1290 SKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESK 1349
Query: 602 DRLSHERHQF-------QRDKEATQELIEDLRK--------------QLEHLQLLKLEAE 640
D E+ Q+ +R KE +E I D K L+ +L+K + +
Sbjct: 1350 DLFHVEQRQYIDKLNELRRQKEKLEEKIMDQYKFYDPSPPRRRGNWITLKMRKLIKSKKD 1409
Query: 641 QRRGRSSSMGLQEYHSRARESELE 664
R R S+ L S + E L+
Sbjct: 1410 INRERQKSLTLTPTRSDSSEGFLQ 1433
Score = 49.7 bits (117), Expect = 1e-05
Identities = 69/302 (22%), Positives = 132/302 (43%), Gaps = 50/302 (16%)
Query: 436 LHQSGALTMEALEDPSPELMEGPEEDIADKVVFLERRVLELEKDTAATGEQHSRLRQENL 495
+++ + ++ LE + EL++ DI V E V E K +Q N
Sbjct: 875 IYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKT-----------QQMNN 923
Query: 496 QLVHRANALEE-QLKEQELRACEMVLEETRRQKELLCKMER--EKSIEIEN-----LQTR 547
L + LE+ L ++ L E +++R K L K+E +KS+EI+ L+ R
Sbjct: 924 DLEKLTHELEKIGLNKERLLHDEQSTDDSR-YKLLESKLESTLKKSLEIKEEKIAALEAR 982
Query: 548 LQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLRLSEEQENKRRMGDRLSHE 607
L++ N +LR +K N E L++ +++E + +S E
Sbjct: 983 LEESTNYNQQLRQELKTVKKNYEALKQR----------------QDEERMVQSSPPISGE 1026
Query: 608 RHQFQRD-KEATQELIEDLRKQLE----------HLQLLKLEAEQRRGRSSSMGLQEYHS 656
++++R+ +E T+EL++ + +E Q LK + +Q +++++ Q
Sbjct: 1027 DNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILAL 1086
Query: 657 RARESELEQEVRRLKQDNRNLKEQNEELNGQIITLSIQGAKSLFSTAFSESLAAEISSVS 716
+ + L+++ L+ N L+ +N LN Q +L Q A+ L SL E SV
Sbjct: 1087 QRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQ---QSSLENENESVI 1143
Query: 717 RD 718
++
Sbjct: 1144 KE 1145
Score = 48.1 bits (113), Expect = 3e-05
Identities = 87/420 (20%), Positives = 176/420 (41%), Gaps = 93/420 (22%)
Query: 387 EEHFEDYGEGSEAE----LSPETLCNGQLGCSDPAFLTPSPTKRLS-----SKKVARYLH 437
+EH E E SE P + Q C P + LS +K R L
Sbjct: 205 DEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGMKRTESRQHLSVELADAKAKIRRLR 264
Query: 438 QSGALTMEALEDPSPELMEGPEEDIADKVVFLERRVLELEKDTAATGEQHSRLRQENLQL 497
Q LE+ + +L++ +E LE+ +EL+ RL+QEN+ L
Sbjct: 265 QE-------LEEKTEQLLDCKQE--------LEQMEIELK-----------RLQQENMNL 298
Query: 498 VHRANALE------EQLKEQELRACEMVLEETRRQKELLCKMEREKSIEIENLQTRLQQL 551
+ A + + L+E+ +R ++ E +R +E+ +IE + R+++L
Sbjct: 299 LSDARSARMYRDELDALREKAVRVDKLESEVSRY---------KERLHDIEFYKARVEEL 349
Query: 552 DEENS------------------------ELRSCTPCLKANIERLEEEK---QKLLDEI- 583
E+N EL LKA + +E E+ +K ++E+
Sbjct: 350 KEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELM 409
Query: 584 -ESLTLRLSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHL---QLLKLEA 639
E++TL ++++Q + L E Q R E ++ + L ++ L +LLKLE
Sbjct: 410 EENMTLEMAQKQSMDESL--HLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEM 467
Query: 640 EQRRGRSSSMGLQEYHSRARESE-LEQEVRRLKQDNRNLKEQNEELNGQII--TLSIQGA 696
E +S + ++E + E ++ +++++N+ L ++ E L +I+ S+Q
Sbjct: 468 E---NQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNC 524
Query: 697 KSLFSTAFSESLAAEISSVSRDELMEAIQKQEEINFRLQDYIDRIIVAIMETNPSILEVK 756
++L E E + + L E ++Q +I + +++++ + ++ + + E +
Sbjct: 525 QNLSKDLMKEKAQLE---KTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEAR 581
Score = 42.7 bits (99), Expect = 0.001
Identities = 63/305 (20%), Positives = 129/305 (42%), Gaps = 61/305 (20%)
Query: 469 LERRVLELEKDTAATGEQ---HSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRR 525
LE + LE EK+ G + S + E L++ ++ +E Q ++ L +++
Sbjct: 725 LENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLES 784
Query: 526 QKELLCKMEREKSIEIENLQT---RLQQLDEENSELRSCTPCLKANIERLEEEKQKLLD- 581
+ + L + +E L+ RL+QL++EN L T L+ + ++LE+E ++L
Sbjct: 785 ELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQ 844
Query: 582 -EIESLTL-----------------------------RLSEEQENKRRMGDRLSHE---- 607
EI+ TL RL E ++ + + R + +
Sbjct: 845 AEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTL 904
Query: 608 ---RHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARESELE 664
R +K TQ++ DL K L+ + L E+ S Y + ES+LE
Sbjct: 905 VTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRY--KLLESKLE 962
Query: 665 QEVRRLKQDNRNLKEQNEELNGQIITLSIQGAKSLFSTAFSESLAAEISSVSRDELMEAI 724
+++ + +KE+ ++ A+ ST +++ L E+ +V ++ EA+
Sbjct: 963 STLKK----SLEIKEEK---------IAALEARLEESTNYNQQLRQELKTVKKN--YEAL 1007
Query: 725 QKQEE 729
+++++
Sbjct: 1008 KQRQD 1012
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 67.8 bits (164), Expect = 4e-11
Identities = 75/318 (23%), Positives = 145/318 (45%), Gaps = 47/318 (14%)
Query: 453 ELMEGPEEDIADKVVFL-ERRVLELEKDTAATGEQHSRLR-----------------QEN 494
EL E P++ + +V L R+L+LE + + + LR +EN
Sbjct: 441 ELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKEN 500
Query: 495 LQLVHRANALEEQL--KEQELRACEMVLEETRRQKELLCKMEREKSIEI--ENLQTRLQQ 550
+L + LE ++ ++Q L+ C+ + ++ ++K L EK+IE EN + +++
Sbjct: 501 QRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQL-----EKTIETLRENSERQIKI 555
Query: 551 LDEENSELRSCTPCLK--------ANIERLEEEKQKLLDEIESLTLRLSEEQENKRRMGD 602
L++EN L L+ A ++ +E+E + L + I+ + +LS+ + KR++
Sbjct: 556 LEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKK 615
Query: 603 RLSHERHQFQRDKEATQELIEDLRKQLEHLQL----LKLEAEQRRGRSSSMGLQEYHSRA 658
L H + + +R +E EL L K+ E LQ LK+ E+ E +R
Sbjct: 616 ELEHYKEKGERAEELENEL-HHLEKENELLQKKITNLKITCEKIEALEQENSELERENRK 674
Query: 659 RESELEQ------EVRRLKQDNRNLKEQNEELNGQIITLSIQGAKSLFSTAFSESLAAEI 712
+ L+ ++ L+++N L E+N EL + +L K ++ L +E
Sbjct: 675 LKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEK 734
Query: 713 SSVSRD-ELMEAIQKQEE 729
+ + EL++A K+ E
Sbjct: 735 EQLKKGLELLKASFKKTE 752
Score = 58.5 bits (140), Expect = 2e-08
Identities = 71/313 (22%), Positives = 134/313 (42%), Gaps = 36/313 (11%)
Query: 455 MEGPEEDIADKVVFLERRVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQELR 514
+E ++ +++ L+R+ + L++ Q+++L+ EN L ++ +L Q + ++
Sbjct: 1071 LETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQ 1130
Query: 515 AC------EMVLEETRRQKEL---LCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCL 565
E V++E K L L K + + E + + L ++ L+S L
Sbjct: 1131 QSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNL 1190
Query: 566 KANIERLEEEKQKLLDE---IESLTLRLSEEQEN---------------KRRMG--DRLS 605
+ LE+ +LL + +E L L EQE K+ G DRL+
Sbjct: 1191 EVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLN 1250
Query: 606 HERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRA--RESEL 663
H Q ++ E Q ++L+ L + +L EQ R + L+E + + ++L
Sbjct: 1251 HTYSQLLKETEVLQTDHKNLKSLLNNSKL-----EQTRLEAEFSKLKEQYQQLDITSTKL 1305
Query: 664 EQEVRRLKQDNRNLKEQNEELNGQIITLSIQGAKSLFSTAFSESLAAEISSVSRDELMEA 723
+ L Q NL+E+N L QI TL +Q L S+ L D+L E
Sbjct: 1306 NNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNEL 1365
Query: 724 IQKQEEINFRLQD 736
+++E++ ++ D
Sbjct: 1366 RRQKEKLEEKIMD 1378
Score = 52.4 bits (124), Expect = 2e-06
Identities = 62/264 (23%), Positives = 112/264 (42%), Gaps = 34/264 (12%)
Query: 427 LSSKKVARYLHQSGALTMEALEDPSPELME--GPEEDIADKVVFLERRVLELEKDTAATG 484
+S + H++ + LED +L++ G ED+ + + ++L K+
Sbjct: 1177 ISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVA 1236
Query: 485 EQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELLCKMEREKS---IEI 541
++ +L EN +L H + L L+ E++ + + K LL + E++ E
Sbjct: 1237 AEYKKLCGENDRLNHTYSQL--------LKETEVLQTDHKNLKSLLNNSKLEQTRLEAEF 1288
Query: 542 ENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLRLSEEQENKRRMG 601
L+ + QQLD +++L + L LEEE + LLD+I++L L+ E
Sbjct: 1289 SKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESK 1348
Query: 602 DRLSHERHQF-------QRDKEATQELIEDLRK--------------QLEHLQLLKLEAE 640
D E+ Q+ +R KE +E I D K L+ +L+K + +
Sbjct: 1349 DLFHVEQRQYIDKLNELRRQKEKLEEKIMDQYKFYDPSPPRRRGNWITLKMRKLIKSKKD 1408
Query: 641 QRRGRSSSMGLQEYHSRARESELE 664
R R S+ L S + E L+
Sbjct: 1409 INRERQKSLTLTPTRSDSSEGFLQ 1432
Score = 52.0 bits (123), Expect = 2e-06
Identities = 65/295 (22%), Positives = 124/295 (42%), Gaps = 37/295 (12%)
Query: 436 LHQSGALTMEALEDPSPELMEGPEEDIADKVVFLERRVLELEKDTAATGEQHSRLRQ-EN 494
+++ + ++ LE + EL++ DI V E V E K + + E
Sbjct: 875 IYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEK 934
Query: 495 LQLVHRANALEEQLKEQELRACEMVLEETRRQKELLCKMEREKSIEIENLQTRLQQLDEE 554
+ L +EQ + + E LE T + K L K E+ I L+ RL++
Sbjct: 935 IGLNKERLLHDEQSTDDRYKLLESKLESTLK-KSLEIKEEK-----IAALEARLEESTNY 988
Query: 555 NSELRSCTPCLKANIERLEEEKQKLLDEIESLTLRLSEEQENKRRMGDRLSHERHQFQRD 614
N +LR +K N E L++ +++E + +S E ++++R+
Sbjct: 989 NQQLRQELKTVKKNYEALKQR----------------QDEERMVQSSPPISGEDNKWERE 1032
Query: 615 -KEATQELIEDLRKQLE----------HLQLLKLEAEQRRGRSSSMGLQEYHSRARESEL 663
+E T+EL++ + +E Q LK + +Q +++++ Q + + L
Sbjct: 1033 SQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSL 1092
Query: 664 EQEVRRLKQDNRNLKEQNEELNGQIITLSIQGAKSLFSTAFSESLAAEISSVSRD 718
+++ L+ N L+ +N LN Q +L Q A+ L SL E SV ++
Sbjct: 1093 QEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQ---QSSLENENESVIKE 1144
Score = 48.1 bits (113), Expect = 3e-05
Identities = 87/420 (20%), Positives = 176/420 (41%), Gaps = 93/420 (22%)
Query: 387 EEHFEDYGEGSEAE----LSPETLCNGQLGCSDPAFLTPSPTKRLS-----SKKVARYLH 437
+EH E E SE P + Q C P + LS +K R L
Sbjct: 205 DEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGMKRTESRQHLSVELADAKAKIRRLR 264
Query: 438 QSGALTMEALEDPSPELMEGPEEDIADKVVFLERRVLELEKDTAATGEQHSRLRQENLQL 497
Q LE+ + +L++ +E LE+ +EL+ RL+QEN+ L
Sbjct: 265 QE-------LEEKTEQLLDCKQE--------LEQMEIELK-----------RLQQENMNL 298
Query: 498 VHRANALE------EQLKEQELRACEMVLEETRRQKELLCKMEREKSIEIENLQTRLQQL 551
+ A + + L+E+ +R ++ E +R +E+ +IE + R+++L
Sbjct: 299 LSDARSARMYRDELDALREKAVRVDKLESEVSRY---------KERLHDIEFYKARVEEL 349
Query: 552 DEENS------------------------ELRSCTPCLKANIERLEEEK---QKLLDEI- 583
E+N EL LKA + +E E+ +K ++E+
Sbjct: 350 KEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELM 409
Query: 584 -ESLTLRLSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHL---QLLKLEA 639
E++TL ++++Q + L E Q R E ++ + L ++ L +LLKLE
Sbjct: 410 EENMTLEMAQKQSMDESL--HLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEM 467
Query: 640 EQRRGRSSSMGLQEYHSRARESE-LEQEVRRLKQDNRNLKEQNEELNGQII--TLSIQGA 696
E +S + ++E + E ++ +++++N+ L ++ E L +I+ S+Q
Sbjct: 468 E---NQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNC 524
Query: 697 KSLFSTAFSESLAAEISSVSRDELMEAIQKQEEINFRLQDYIDRIIVAIMETNPSILEVK 756
++L E E + + L E ++Q +I + +++++ + ++ + + E +
Sbjct: 525 QNLSKDLMKEKAQLE---KTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEAR 581
Score = 42.7 bits (99), Expect = 0.001
Identities = 59/292 (20%), Positives = 125/292 (42%), Gaps = 36/292 (12%)
Query: 469 LERRVLELEKDTAATGEQ---HSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRR 525
LE + LE EK+ G + S + E L++ ++ +E Q ++ L +++
Sbjct: 725 LENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLES 784
Query: 526 QKELLCKMEREKSIEIENLQT---RLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDE 582
+ + L + +E L+ RL+QL++EN L T L+ + ++LE+E ++L +
Sbjct: 785 ELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQ 844
Query: 583 IESLTLRLSE--------EQENKRRMGDRLSHERHQFQRDKEATQE-------------- 620
E L E E+ENK + + + R KE +E
Sbjct: 845 AEIKDTTLEENNVKIGNLEKENK-TLSKEIGIYKESCVRLKELEKENKELVKRATIDIKT 903
Query: 621 ---LIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARESELEQEVRRLKQDNRNL 677
L EDL + Q + + E+ +GL + E + + L+ +
Sbjct: 904 LVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLEST 963
Query: 678 KEQNEELNGQIITLSIQGAKSLFSTAFSESLAAEISSVSRDELMEAIQKQEE 729
+++ E+ + ++ A+ ST +++ L E+ +V ++ EA++++++
Sbjct: 964 LKKSLEIKEE--KIAALEARLEESTNYNQQLRQELKTVKKN--YEALKQRQD 1011
>gi|34577114 cytomatrix protein p110 [Homo sapiens]
Length = 957
Score = 67.8 bits (164), Expect = 4e-11
Identities = 74/331 (22%), Positives = 148/331 (44%), Gaps = 61/331 (18%)
Query: 459 EEDIADKVVFLERRVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQE------ 512
EE +++K +ER + E+D E+ R+EN L + NAL+ +L E+E
Sbjct: 587 EEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDL 646
Query: 513 -----------------LRACEMVLEETRRQ-KELLCKMEREKSIEIEN-----LQTRLQ 549
L++ E+ +E+ + + +L ++++ +IE ++ +++
Sbjct: 647 KEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAHNIEDDSRMNPEFADQIK 706
Query: 550 QLDEENSELRSCTPCLKANIERLEE----------EKQKLLDEIESLTLRLSEEQENKRR 599
QLD+E S R +A ++RL E +K K + E+ESLTLR ++Q K
Sbjct: 707 QLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTLRHMKDQNKK-- 764
Query: 600 MGDRLSHERHQFQRDKEATQELIEDLRKQ-------LEHLQLLKLEAEQRRGRSSSMGLQ 652
+++ +H Q +K+ +L+E++R++ +HLQ+ +L + R +
Sbjct: 765 ----VANLKHNQQLEKKKNAQLLEEVRRREDSMADNSQHLQIEELMNALEKTRQELDATK 820
Query: 653 EYHSRARESELEQE-------VRRLKQDNRNLKEQNEELNGQIITLSIQGAKSLFSTAFS 705
+ ++S E+E + R KQ L+ + E L I A S +
Sbjct: 821 ARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEALLAAISEKDANIALLELSASKK 880
Query: 706 ESLAAEISSVSR--DELMEAIQKQEEINFRL 734
+ E+ ++ R D L+ +++Q + +L
Sbjct: 881 KKTQEEVMALKREKDRLVHQLKQQTQNRMKL 911
Score = 60.8 bits (146), Expect = 4e-09
Identities = 71/302 (23%), Positives = 131/302 (43%), Gaps = 48/302 (15%)
Query: 473 VLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELLCK 532
V+E++ A+ E++ R ++ +Q++ L + +E+E++ E+ ++ K + +
Sbjct: 379 VIEMKDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQ 438
Query: 533 MERE---KSIEIENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLR 589
+++E K E+ LQT+L+ L +NS+ + LK ++ E+ L E+++L LR
Sbjct: 439 LKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLR 498
Query: 590 LSEEQE--NK-------------------RRMGDRLSHERHQ---FQRDKEATQELIEDL 625
L E++ NK R M D L + + Q+ E QE + D
Sbjct: 499 LEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDK 558
Query: 626 RKQLEHLQ----------------LLKLEAEQRRGRSSSMGLQEYHSRARESELEQEVRR 669
KQL +L+ L LE L+E R LE E+
Sbjct: 559 DKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLE-EIES 617
Query: 670 LKQDNRNLKEQNEELNGQII--TLSIQGAKSLFSTAFSESLAAEISSVSRDELMEAIQKQ 727
+++N++LKE+ L ++ S+ K S+ S L + S + +E QK+
Sbjct: 618 FRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIE--QKK 675
Query: 728 EE 729
EE
Sbjct: 676 EE 677
Score = 35.8 bits (81), Expect = 0.15
Identities = 48/214 (22%), Positives = 92/214 (42%), Gaps = 29/214 (13%)
Query: 507 QLKEQELRACEMVLEETRRQKELLCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCLK 566
+L E+ R + + ++ LL K E + IE + L DE +L
Sbjct: 257 ELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKG 316
Query: 567 ANIERLEE--EKQKLLDEIES----LTLRLSEEQENKRRMGDRLSHERHQFQRD---KEA 617
+ LE+ E+ + + E ES L + L ++++ + + L H R Q Q + +A
Sbjct: 317 LPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREEL-HRRSQLQPEPAKTKA 375
Query: 618 TQELIE-----------DLRKQLEHLQLLK----LEAEQRRGRSSSMGLQEYHSRARESE 662
Q +IE ++R + +Q+LK L E R + + + HS+ +++
Sbjct: 376 LQTVIEMKDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTK 435
Query: 663 LEQEVRRLKQDNRNLKEQNEELNGQIITLSIQGA 696
++Q LKQ+ + + L ++ TLS Q +
Sbjct: 436 IDQ----LKQELSKKESELLALQTKLETLSNQNS 465
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 67.4 bits (163), Expect = 5e-11
Identities = 74/314 (23%), Positives = 135/314 (42%), Gaps = 35/314 (11%)
Query: 455 MEGPEEDIADKVVFLERRVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQELR 514
+E E++ ++ LE LE++ + + RQ N L RA L +QL+ ++
Sbjct: 721 LEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEI 780
Query: 515 ACEMVLEETRRQ------KELLCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKAN 568
L+ ++ K+ L K E EK I ++ +T Q+ ++ EL +
Sbjct: 781 VSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTE 840
Query: 569 IERLEEEKQKLLDEIESLTLRLSE------------EQENKRRMGDRLSHER------HQ 610
+++++ EK+ L+ E+ ++ +LS+ E+EN++ L E+ HQ
Sbjct: 841 LQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQ 900
Query: 611 FQRDKEAT----QELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARESELEQE 666
Q E T +EL + L K+ E LKLE + + + E +L+
Sbjct: 901 LQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGN 960
Query: 667 VRRLKQDNRNLKEQNEELNGQIITLSIQGAK-----SLFSTAFSESLAAEISSVSRDELM 721
+ LKQ + K+Q E L G++ +Q + T ++ LAAE +S L
Sbjct: 961 INELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKIS--VLQ 1018
Query: 722 EAIQKQEEINFRLQ 735
+K +E +LQ
Sbjct: 1019 NNYEKSQETFKQLQ 1032
Score = 62.8 bits (151), Expect = 1e-09
Identities = 66/279 (23%), Positives = 129/279 (46%), Gaps = 22/279 (7%)
Query: 470 ERRVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQK-- 527
+ ++++ K AT EQ S +++ LQ R AL++ KE+ L+ E+V E+++ +
Sbjct: 1073 QNKLIQELKTAKATLEQDSAKKEQQLQ--ERCKALQDIQKEKSLKEKELVNEKSKLAEIE 1130
Query: 528 ELLCKMERE-------------KSI-EIENLQTRLQQLDEENSELRSCTPCLKANIERLE 573
E+ C+ E+E +SI EI NL+ Q L ++ EL+ LKA +E+ +
Sbjct: 1131 EIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEK 1190
Query: 574 EEKQKLLDEIESLTLRLSEE-QENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHL 632
+Q L D+++ L +E E + ++ + + ++ +E +L + E+L
Sbjct: 1191 RNQQILKDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENL 1250
Query: 633 QLLKLEAEQRRGRSSSMGLQEYHSRARESELEQEVRRLKQDNRNLKEQNEELNGQIITLS 692
+K E + + R S + Q R + LE V+ + + R L E+ + G+I L
Sbjct: 1251 GTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKGEGEIEKLQ 1310
Query: 693 IQGAKSLFSTAFSESLAAEISSVSRDELMEAIQKQEEIN 731
K L ++ A + + R+ I+ + +N
Sbjct: 1311 ---TKVLELQRKLDNTTAAVQELGRENQSLQIKHTQALN 1346
Score = 57.8 bits (138), Expect = 4e-08
Identities = 70/302 (23%), Positives = 138/302 (45%), Gaps = 55/302 (18%)
Query: 469 LERRVLELEKDTAATGEQHSRLRQE----------------NLQLVHRANALEEQLKEQE 512
L ++LE E+ GE H RL+++ +LQL + + LEEQLKE+
Sbjct: 419 LHSKLLETERQL---GEAHGRLKEQRQLSSEKLMDKEQQVADLQL--KLSRLEEQLKEKV 473
Query: 513 LRACEMV--LEETRRQKELLCKMEREKSIEIENLQTRLQQL-------DEENSELRSCTP 563
+ E+ L++T++Q + +++ + ++ Q L+Q+ D++ L +
Sbjct: 474 TNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQ 533
Query: 564 CLKANIERLEEEKQKLLDEI---ESLTLRLSEEQENKRRMGDRLSHE----RHQFQRDKE 616
K NI LE+E++ L +I E T L++ QE + ++++ ++Q + K+
Sbjct: 534 KSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQ 593
Query: 617 ATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARESELEQEVRRLKQDNRN 676
A + L + +++Q HL+ A Q R S + E +S+ ES+ ++ Q +
Sbjct: 594 AQENLHDQVQEQKAHLR-----AAQDRVLSLETSVNELNSQLNESK-----EKVSQLDIQ 643
Query: 677 LKEQNEELNGQIITLSIQGAKSLFSTAFSESL--AAEISSVSRDELMEAIQKQEEINFRL 734
+K + E + LS + AK+ L A + EL + + +++ +L
Sbjct: 644 IKAKTE------LLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKL 697
Query: 735 QD 736
QD
Sbjct: 698 QD 699
Score = 46.6 bits (109), Expect = 9e-05
Identities = 64/311 (20%), Positives = 129/311 (41%), Gaps = 44/311 (14%)
Query: 464 DKVVFLERRVLELEKDTAATGEQHSRL------RQENLQLVHRANALEEQLKEQELRACE 517
D+V+ LE V EL + E+ S+L + E L A + + L +
Sbjct: 614 DRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQ 673
Query: 518 MVLEETRRQ--------KELLCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKANI 569
L++ +++ ++ K++ +K L++ L++ E+ L T L+ I
Sbjct: 674 NALQDKQQELNKITTQLDQVTAKLQ-DKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQI 732
Query: 570 ERLEEEKQKLLDEIESLTLRLSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQL 629
++LE + ++ E L ++++ + R + Q + +KE DL+K+
Sbjct: 733 KKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKS 792
Query: 630 EHLQLLKLEAEQRRGRSSSMGLQEYHSRARESELEQEVRRLKQD----NRNLKEQNEELN 685
E L+ +K + ++ E+E + LKQD ++ K Q+EELN
Sbjct: 793 EALESIKQKLTKQ---------------------EEEKQILKQDFETLSQETKIQHEELN 831
Query: 686 GQIITLSIQGAKSLFSTAFSESLAAEISSVSRDELMEAIQKQEEINFRLQDYIDRIIVAI 745
+I T + K E+L E+S+V +D+L + + + + AI
Sbjct: 832 NRIQTTVTELQKVKME---KEALMTELSTV-KDKLSKVSDSLKNSKSEFEKENQKGKAAI 887
Query: 746 METNPSILEVK 756
++ + E+K
Sbjct: 888 LDLEKTCKELK 898
Score = 46.2 bits (108), Expect = 1e-04
Identities = 62/283 (21%), Positives = 126/283 (44%), Gaps = 21/283 (7%)
Query: 463 ADKVVFLERRVLELEKDTAATGEQHSRLRQENLQLVHR-ANALEEQLKEQELRACEMVLE 521
AD++ V + D+ GE + L+++++ L+ + L+ LKE++ + E+ E
Sbjct: 53 ADELFKHYEAVHDAGNDSGHGGESNLALKRDDVTLLRQEVQDLQASLKEEKWYSEELKKE 112
Query: 522 ETRRQKELLCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLD 581
+ Q L + E + + + LQ L+++ E ++ +K + E++ +L
Sbjct: 113 LEKYQG--LQQQEAKPDGLVTDSSAELQSLEQQLEEAQTENFNIKQMKDLFEQKAAQLAT 170
Query: 582 EIESLTLRLSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDL--RKQLEHLQLLKLEA 639
EI + + EE+ + +++ + ++ Q+L +L R +E + +LK E
Sbjct: 171 EIADIKSKYDEERSLREAAEQKVTRLTEELNKEATVIQDLKTELLQRPGIEDVAVLKKEL 230
Query: 640 EQRRGRSSSMGLQEYHSRARESELEQEVRRLKQDNRNLKEQNEELNGQIITLSIQGAKSL 699
Q + +M L+ R RESE +LK + + L+ Q I L + AK
Sbjct: 231 VQVQTLMDNMTLE----RERESE------KLKDECKKLQSQYASSEATISQLRSELAKGP 280
Query: 700 FSTA-FSESLAAEISSVS-----RDELMEAIQKQEEINFRLQD 736
A + + L SSV+ L E + K+E+ +L++
Sbjct: 281 QEVAVYVQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEE 323
Score = 39.7 bits (91), Expect = 0.010
Identities = 52/253 (20%), Positives = 110/253 (43%), Gaps = 31/253 (12%)
Query: 442 LTMEALEDPSPELMEGPEEDIADKVVFLERRVLELEKDTAATGEQHSRLRQENLQLVHRA 501
L E L+ P E + ++++ ++ LE E+++ ++ +L+ +
Sbjct: 210 LKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDECKKLQSQYASSEATI 269
Query: 502 NALEEQLKEQELRACEMVLEETRRQKELLCKMEREKSIEIENLQTRLQ---QLDEENSEL 558
+ L +L + V +E ++ K + ++ ++ ENL + Q +L+E+++E
Sbjct: 270 SQLRSELAKGPQEVAVYV-QELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNE- 327
Query: 559 RSCTPCLKANIERLEEEKQKLLDEIESLTLRLSEEQENKRRMGDRLSHERHQFQRDKEAT 618
K NI+ +K +++S RLS + + R+ LS + EAT
Sbjct: 328 ---ESVSKKNIQATLHQKDLDCQQLQS---RLSASETSLHRIHVELSEKG-------EAT 374
Query: 619 QELIEDLRK---QLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARESELEQEVRRLKQDNR 675
Q+L E+L + + +HL+ + +Q+R GLQ L+ E+ +L
Sbjct: 375 QKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQ----------LQSEINQLHSKLL 424
Query: 676 NLKEQNEELNGQI 688
+ Q E +G++
Sbjct: 425 ETERQLGEAHGRL 437
Score = 37.4 bits (85), Expect = 0.052
Identities = 62/316 (19%), Positives = 122/316 (38%), Gaps = 30/316 (9%)
Query: 428 SSKKVARYLHQSGALTMEALEDPSPELMEGPEEDIADKVVFLERRVLELEKDTAATGEQH 487
+SK +Q G + LE EL + + + + + LEK+ A+ +
Sbjct: 871 NSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLK 930
Query: 488 SRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELLCKMEREKSIEIENLQTR 547
L QL+ N L++ KE++ + + E ++ E +K +IE LQ
Sbjct: 931 LELNSMQEQLIQAQNTLKQNEKEEQ--QLQGNINELKQSSE-------QKKKQIEALQGE 981
Query: 548 LQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLRLSEEQENKRRMGDRLSHE 607
L+ + +EL + +L+++ + E+ + ++S Q N + +
Sbjct: 982 LKIAVLQKTELEN----------KLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQL 1031
Query: 608 RHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARESELEQEV 667
+ F + +DL+ E L L + + R + + + ++ LEQ+
Sbjct: 1032 QSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDS 1091
Query: 668 RRLKQDNRNLKEQNEELNGQIITLSIQGAKSLFSTAF--SESLAAEISSVSRDELMEAIQ 725
+ +Q L+E+ + L IQ KSL +S AEI + + E +
Sbjct: 1092 AKKEQ---QLQERCKALQ------DIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITK 1142
Query: 726 KQEEINFRLQDYIDRI 741
EE+ + I I
Sbjct: 1143 LNEELKSHKLESIKEI 1158
>gi|14165274 golgi-associated microtubule-binding protein HOOK3
[Homo sapiens]
Length = 718
Score = 67.0 bits (162), Expect = 6e-11
Identities = 91/344 (26%), Positives = 146/344 (42%), Gaps = 53/344 (15%)
Query: 453 ELM--EGPEEDIADKVVFLERRVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKE 510
ELM E P D V L+R +L+K T E S ++E Q H + L+E
Sbjct: 156 ELMSKESPVSAGNDAYVDLDR---QLKKTTEELNEALSA-KEEIAQRCHELDMQVAALQE 211
Query: 511 QE--LRACEMVLEETRRQKELLCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKAN 568
++ L A VL E Q + + LQT+L+QL EE L + +
Sbjct: 212 EKSSLLAENQVLMERLNQSDSIEDPNSPAGRRHLQLQTQLEQLQEETFRLEAAKDDYRIR 271
Query: 569 IERLEEEKQKLLDEIESLTLRLSEEQENK------RRMGDRLSHERHQFQRDKEATQELI 622
E LE+E +L + + LT E Q K R D++S Q + K+ ++L
Sbjct: 272 CEELEKEISELRQQNDELTTLADEAQSLKDEIDVLRHSSDKVSKLEGQVESYKKKLEDL- 330
Query: 623 EDLRKQLEHLQ---------LLKLEAEQRRGRSSSMGLQEY------------------- 654
DLR+Q++ L+ + LE E R+ ++ L+ Y
Sbjct: 331 GDLRRQVKLLEEKNTMYMQNTVSLEEELRKANAARSQLETYKRQVVELQNRLSEESKKAD 390
Query: 655 -----HSRARE--SELEQEVRRLKQDNRNLKEQNEEL---NGQIITLSIQGAKSLFSTAF 704
+ R +E L++E RL+ + +LKE EEL Q L+ QG L S
Sbjct: 391 KLDFEYKRLKEKVDSLQKEKDRLRTERDSLKETIEELRCVQAQEGQLTTQGLMPLGSQES 450
Query: 705 SESLAAEISSVSRDELMEAIQKQEEINFRLQDYIDRIIVAIMET 748
S+SLAAEI + E + +Q + ++ Q+ D +A++++
Sbjct: 451 SDSLAAEIVTPEIREKLIRLQHENKMLKLNQEGSDNEKIALLQS 494
Score = 53.9 bits (128), Expect = 5e-07
Identities = 92/369 (24%), Positives = 154/369 (41%), Gaps = 73/369 (19%)
Query: 430 KKVARYLHQSGALTMEALEDPSPELMEGPEEDI----ADKVVFLERRVLELEKDTAATGE 485
K+++ Q+ LT L D + L + E D+ +DKV LE +V +K G+
Sbjct: 277 KEISELRQQNDELT--TLADEAQSLKD--EIDVLRHSSDKVSKLEGQVESYKKKLEDLGD 332
Query: 486 ---QHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELLCKMEREKSIEIE 542
Q L ++N + +LEE+L++ A LE +RQ +
Sbjct: 333 LRRQVKLLEEKNTMYMQNTVSLEEELRKAN--AARSQLETYKRQ--------------VV 376
Query: 543 NLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLT-----LRLSEEQENK 597
LQ RL + ++ +L LK ++ L++EK +L E +SL LR + QE +
Sbjct: 377 ELQNRLSEESKKADKLDFEYKRLKEKVDSLQKEKDRLRTERDSLKETIEELRCVQAQEGQ 436
Query: 598 RRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQ----LLKLEAEQRRGRSSSMGLQE 653
L Q D A + + ++R++L LQ +LKL E ++ LQ
Sbjct: 437 LTT-QGLMPLGSQESSDSLAAEIVTPEIREKLIRLQHENKMLKLNQEGSDNEKIAL-LQS 494
Query: 654 YHSRA--RESELEQEVRRLKQDNRNLKEQNEELNGQIITLSIQGAKSLFSTAFSESLAAE 711
A R++ELE E R + Q ++ Q EEL +L QG+K+ S + L
Sbjct: 495 LLDDANLRKNELETENRLVNQRLLEVQSQVEELQK---SLQDQGSKAEDSVLLKKKLEEH 551
Query: 712 I--------------------------SSVSRDELMEAIQKQEE----INFRLQDYIDRI 741
+ SS+ +EL EA++K+EE + R + Y+++
Sbjct: 552 LEKLHEANNELQKKRAIIEDLEPRFNNSSLKIEELQEALRKKEEEMKQMEERYKKYLEKA 611
Query: 742 IVAIMETNP 750
I +P
Sbjct: 612 KSVIRTLDP 620
Score = 38.5 bits (88), Expect = 0.023
Identities = 61/265 (23%), Positives = 112/265 (42%), Gaps = 38/265 (14%)
Query: 424 TKRLSSKKVARYLH----QSGALTMEAL------EDPSPELMEGPEEDIADKVVFLERRV 473
T+R S K+ L Q G LT + L E E +I +K++ L+
Sbjct: 415 TERDSLKETIEELRCVQAQEGQLTTQGLMPLGSQESSDSLAAEIVTPEIREKLIRLQHEN 474
Query: 474 LELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELLCKM 533
L+ + + + L Q L+ AN + +L E E R L E + Q E L K
Sbjct: 475 KMLKLNQEGSDNEKIALLQS---LLDDANLRKNEL-ETENRLVNQRLLEVQSQVEELQKS 530
Query: 534 EREKSIEIEN-------LQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESL 586
+++ + E+ L+ L++L E N+EL+ +A IE LE +
Sbjct: 531 LQDQGSKAEDSVLLKKKLEEHLEKLHEANNELQK----KRAIIEDLE-------PRFNNS 579
Query: 587 TLRLSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDL-----RKQLEHLQLLKLEAEQ 641
+L++ E QE R+ + + ++++ E + +I L + +Q LK + ++
Sbjct: 580 SLKIEELQEALRKKEEEMKQMEERYKKYLEKAKSVIRTLDPKQNQGAAPEIQALKNQLQE 639
Query: 642 RRGRSSSMGLQEYHSRARESELEQE 666
R S+ +EY + E+E++
Sbjct: 640 RDRLFHSLE-KEYEKTKSQREMEEK 663
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 66.6 bits (161), Expect = 8e-11
Identities = 58/233 (24%), Positives = 104/233 (44%), Gaps = 21/233 (9%)
Query: 453 ELMEGPEEDIADKVVFLERRVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQE 512
+L EE+ ++ + LE E ++ EQ R QE + EE+ +Q
Sbjct: 475 QLKRDQEEERRERWLKLEE---EERREQQERREQQLRREQEERREQRLKRQEEEERLQQR 531
Query: 513 LRACEMVLEETRRQKELLCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKANIERL 572
LR+ + + E ++E L K E EK +E E + RL++ EE + ++R
Sbjct: 532 LRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQL---------LKRE 582
Query: 573 EEEKQKLL--DEIESLTLRLSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQLE 630
EE +Q+ L ++ E L RL E+ + +R + + ++E Q+L++ ++
Sbjct: 583 EERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEER 642
Query: 631 HLQLLKLEAEQRRGRSSSMGLQEYHSRARESELEQEVRRLKQDNRNLKEQNEE 683
Q L+ E ++RR Q E LEQ ++R ++ R +E EE
Sbjct: 643 RQQQLRREQQERRE-------QRLKREEEEERLEQRLKREHEEERREQELAEE 688
Score = 63.2 bits (152), Expect = 9e-10
Identities = 74/244 (30%), Positives = 111/244 (45%), Gaps = 29/244 (11%)
Query: 452 PELMEGPEEDI-ADKVVFLERRVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKE 510
P L E E + A++ E+R L E++ Q R R++ LQ + EEQL+
Sbjct: 788 PPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQR-REREKELQFLEE----EEQLQR 842
Query: 511 QELRACEMVLEETRRQKELLCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKANIE 570
+E RA ++ EE Q++ ER +S E Q QL+EE R A E
Sbjct: 843 RE-RAQQLQEEEDGLQED----QERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQE 897
Query: 571 RLEEEKQKLLDEIESL-----TLRLSEEQENKRRMGDRLSHERHQF---QRDKEATQELI 622
+L +E+Q L +E E L R +EQE + R ++L E Q +R+K QE
Sbjct: 898 QLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERE 957
Query: 623 EDLRK----QLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARESELEQEVRRLKQDNRNLK 678
RK Q + QLL E E+RR + +E E EL+QE +L ++ R +
Sbjct: 958 RQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYRE------EEELQQEEEQLLREEREKR 1011
Query: 679 EQNE 682
+ E
Sbjct: 1012 RRQE 1015
Score = 62.0 bits (149), Expect = 2e-09
Identities = 69/262 (26%), Positives = 122/262 (46%), Gaps = 43/262 (16%)
Query: 438 QSGALTMEALEDPSPELMEGPEEDIADKVVFLERRVLELEKDTAATGEQHSRLRQENLQL 497
+ G + ++ EL EG E+ ++K LE+R D E+ R RQE +
Sbjct: 132 EPGQRRRQKRQEQERELAEGEEQ--SEKQERLEQR------DRQRRDEELWRQRQEWQER 183
Query: 498 VHRANALEEQLKEQELRAC------EMVLEETRRQKELL---CKMEREKSIEIENLQTRL 548
R + +E++L++C E EE R++ELL K EK + Q R+
Sbjct: 184 EER------RAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRV 237
Query: 549 QQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLRLSEEQENKRRMGDRLSHER 608
Q +EE E R L+ E+L+EE+ + E++ EE+E R++ ER
Sbjct: 238 FQ-EEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQ-------EEEEQLRKL------ER 283
Query: 609 HQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARESELEQEVR 668
+ +R+++ ++ + LR++ QL + + E+RR + Q+ +E EQ++R
Sbjct: 284 QELRRERQEEEQQQQRLRREQ---QLRRKQEEERREQQEERREQQERREQQEERREQQLR 340
Query: 669 RLKQDNRN---LKEQNEELNGQ 687
R +++ R +EQ EE Q
Sbjct: 341 REQEERREQQLRREQEEERREQ 362
Score = 60.1 bits (144), Expect = 7e-09
Identities = 59/226 (26%), Positives = 109/226 (48%), Gaps = 30/226 (13%)
Query: 460 EDIADKVVFLERRVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMV 519
E+ D+ R +LEL + +Q R RQ+ + ++ +E+E R E V
Sbjct: 202 EEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVF---------QEEEEKEWRKRETV 252
Query: 520 LEETRRQKELLCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQ-- 577
L R+++E L + E ++ E++ + +L++L E ELR ER EEE+Q
Sbjct: 253 L---RKEEEKLQEEEPQRQRELQEEEEQLRKL--ERQELRR---------ERQEEEQQQQ 298
Query: 578 KLLDEIESLTLRLSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKL 637
+L E + LR +E+E + + +R + + Q+++ Q+L + ++ E Q L+
Sbjct: 299 RLRREQQ---LRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERRE--QQLRR 353
Query: 638 EAEQRRGRSSSMGLQEYHSRARESELEQEVRRLKQDNRNLKEQNEE 683
E E+ R QE R ++ EQ++RR +Q R + + E+
Sbjct: 354 EQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQ 399
Score = 60.1 bits (144), Expect = 7e-09
Identities = 71/231 (30%), Positives = 104/231 (45%), Gaps = 32/231 (13%)
Query: 468 FLERRVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQK 527
+ E L+ E++ E+ R RQE + + L++ KE++L E E+ RRQ
Sbjct: 930 YREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQ--KEEQLLGEEP--EKRRRQ- 984
Query: 528 ELLCKMEREKSI-EIENLQTRLQQLDEENSELRSCTPC---LKANIERLEEEKQKLLDEI 583
EREK E E LQ +QL E E R + E +EE+Q L +E
Sbjct: 985 ------EREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREER 1038
Query: 584 ESLTLRLSEEQENKRRMGDRLSHERHQF---QRDKEATQELIEDLRK----QLEHLQLLK 636
E L +E+E + R + L E Q +R+ QEL RK Q E QLL+
Sbjct: 1039 EKRRL---QERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLR 1095
Query: 637 LEAEQRRGRSSSMGLQEYHSRARESELEQEVRRLKQDNRNLKEQNEELNGQ 687
E E+RR + +E E EL+QE +L ++ R K + +EL Q
Sbjct: 1096 EEPEKRRRQERERQCRE------EEELQQEEEQLLREERE-KRRRQELERQ 1139
Score = 59.7 bits (143), Expect = 1e-08
Identities = 60/246 (24%), Positives = 105/246 (42%), Gaps = 10/246 (4%)
Query: 442 LTMEALEDPSPELMEGPEEDIADKVVFLERRVLELEKDTAATGEQHSRLRQENLQLVHRA 501
L E E+ + E+ + K R E ++ EQ R++ L+
Sbjct: 286 LRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEE 345
Query: 502 NALEEQLKEQELRACEMVLEETRRQKELLCKMEREKSIEIENLQTRLQQLDEENSELRSC 561
++ +EQE E L + ++ ++ RE+ + E R QQL E R
Sbjct: 346 RREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQ 405
Query: 562 TPCLKANIERLEE--EKQKLLDEIESLTLRLSEEQENKRRMGDRLSHERHQFQRDKEATQ 619
+ + R ++ +Q+L E E EQE + + R ER + + +E T+
Sbjct: 406 QLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETE 465
Query: 620 ELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARESELEQEVRRLKQDNR--NL 677
++ RKQ QL + + E+RR R + L+E R ++ EQ++RR +++ R L
Sbjct: 466 RHEQERRKQ----QLKRDQEEERRER--WLKLEEEERREQQERREQQLRREQEERREQRL 519
Query: 678 KEQNEE 683
K Q EE
Sbjct: 520 KRQEEE 525
Score = 59.3 bits (142), Expect = 1e-08
Identities = 49/223 (21%), Positives = 108/223 (48%), Gaps = 16/223 (7%)
Query: 467 VFLERRVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQ 526
VF E E K ++ +L++E Q EEQL++ E + +E +Q
Sbjct: 237 VFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQ 296
Query: 527 KELLCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLL--DEIE 584
++ ++ RE+ + + + R +Q +E + + E+ EE +++ L ++ E
Sbjct: 297 QQ---RLRREQQLRRKQEEERREQQEERREQ--------QERREQQEERREQQLRREQEE 345
Query: 585 SLTLRLSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRG 644
+L EQE +RR +L E+ + +R+++ +E + LR++ + + +L EQ+
Sbjct: 346 RREQQLRREQEEERR-EQQLRREQEEERREQQLRRE--QQLRREQQLRREQQLRREQQLR 402
Query: 645 RSSSMGLQEYHSRARESELEQEVRRLKQDNRNLKEQNEELNGQ 687
R + ++ R ++ EQ++RR +++ R+ ++ +E Q
Sbjct: 403 REQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQ 445
Score = 57.4 bits (137), Expect = 5e-08
Identities = 56/215 (26%), Positives = 98/215 (45%), Gaps = 23/215 (10%)
Query: 470 ERRVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKEL 529
E+++L+ E++ E+ R RQE R EEQL+++E + E+ RRQ+
Sbjct: 902 EQQLLQEEEEELQREEREKRRRQEQ----ERQYREEEQLQQEEEQLLREEREKRRRQER- 956
Query: 530 LCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLR 589
ER+ + + Q Q L EE + R + E+ E+++L E E L
Sbjct: 957 ----ERQYRKDKKLQQKEEQLLGEEPEKRR------RQEREKKYREEEELQQEEEQL--- 1003
Query: 590 LSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSM 649
L EE+E +RR Q+++ E QE + LR++ E +L + E + R
Sbjct: 1004 LREEREKRRR-----QEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQ 1058
Query: 650 GLQEYHSRARESELEQEVRRLKQDNRNLKEQNEEL 684
++ RE+ QE+ R + L+++ E+L
Sbjct: 1059 EEEQLLGEERETRRRQELERQYRKEEELQQEEEQL 1093
Score = 56.2 bits (134), Expect = 1e-07
Identities = 67/250 (26%), Positives = 115/250 (46%), Gaps = 37/250 (14%)
Query: 445 EALEDPSPELMEGPEEDIADKVVFLERRVLELEKDTAATGEQHSRLRQENLQLVHRANAL 504
E L++ P+ +E+ +++ LER+ EL ++ +Q RLR+E Q + R
Sbjct: 258 EKLQEEEPQRQRELQEE-EEQLRKLERQ--ELRRERQEEEQQQQRLRRE--QQLRRKQ-- 310
Query: 505 EEQLKEQELRACEMVLEETRRQKELLCKME--REKSIEIENLQTRLQQLDEENSELRSCT 562
EE+ +EQ+ EE R Q+E + E RE+ + E + R QQL E E
Sbjct: 311 EEERREQQ--------EERREQQERREQQEERREQQLRREQEERREQQLRREQEE----- 357
Query: 563 PCLKANIERLEEEKQKLLDEIESLTLRLSEEQENKRRMGDRLSHERHQFQRDKEATQELI 622
ER E++ ++ +E E +L EQ+ +R ++ Q +R+++ +E
Sbjct: 358 -------ERREQQLRREQEE-ERREQQLRREQQLRR---EQQLRREQQLRREQQLRREQQ 406
Query: 623 EDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARESEL--EQEVRR--LKQDNRNLK 678
+QL Q L+ E + RR + Q++ RE L EQE RR LK++ +
Sbjct: 407 LRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETER 466
Query: 679 EQNEELNGQI 688
+ E Q+
Sbjct: 467 HEQERRKQQL 476
Score = 56.2 bits (134), Expect = 1e-07
Identities = 52/221 (23%), Positives = 100/221 (45%), Gaps = 13/221 (5%)
Query: 470 ERRVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKEL 529
E+++ E+D E+ RQE + Q + ++ R E +L+E R+++
Sbjct: 1420 EQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQE--REEQQ 1477
Query: 530 LCKMEREKSIEIENLQTRLQQLDEE--NSELRSCTPCLKANIERLEEEKQKLLDEIESLT 587
L + ER++ E Q R Q+ D + ELRS P K LEEE+Q + +
Sbjct: 1478 LHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKF----LEEEQQLHRQQRQRKF 1533
Query: 588 LRLSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSS 647
L+ ++ + R R +F+ +++ QE E + E + +LE ++ R +
Sbjct: 1534 LQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQ 1593
Query: 648 SMGLQEYHSRARESELEQEV-----RRLKQDNRNLKEQNEE 683
E + R E +Q++ R+ ++D + L+E+ E+
Sbjct: 1594 ERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQ 1634
Score = 55.8 bits (133), Expect = 1e-07
Identities = 55/202 (27%), Positives = 96/202 (47%), Gaps = 22/202 (10%)
Query: 470 ERRVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKEL 529
ERR L+++ EQ RL++E ++ + + E++LK +E EE RRQ+ L
Sbjct: 584 ERRQQRLKREQEERLEQ--RLKREEVERLEQEERREQRLKREEP-------EEERRQQLL 634
Query: 530 LCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLR 589
+ + E+ R QQL E E R + ERLE+ ++ +E E
Sbjct: 635 KSEEQEER---------RQQQLRREQQERREQRLKREEEEERLEQRLKREHEE-ERREQE 684
Query: 590 LSEEQEN--KRRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSS 647
L+EE++ + R+ R+ + Q + + +A Q + ++ E + + + E+RR R S
Sbjct: 685 LAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRES 744
Query: 648 SMGLQEYHSRARESELEQEVRR 669
+ QE RA + E+E RR
Sbjct: 745 ELQWQE-EERAHRQQQEEEQRR 765
Score = 55.8 bits (133), Expect = 1e-07
Identities = 74/277 (26%), Positives = 117/277 (42%), Gaps = 43/277 (15%)
Query: 425 KRLSSKKVARYLHQSGALTMEALEDPSPELMEGPEEDIADKVVFLERRVLELEKDTAATG 484
+R +K ++L + L E +G +ED ERR + ++
Sbjct: 823 QRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQED-------QERRRSQEQRRDQKWR 875
Query: 485 EQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEE-----TRRQKELLCKMEREKSI 539
Q R+ ++ AL+EQL++++ +L+E R ++E + E+E+
Sbjct: 876 WQLEEERKRRRHTLYAKPALQEQLRKEQ-----QLLQEEEEELQREEREKRRRQEQERQY 930
Query: 540 -EIENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESL-----TLRLSEE 593
E E LQ +QL E E R + ER + +KL + E L R +E
Sbjct: 931 REEEQLQQEEEQLLREEREKRR-----RQERERQYRKDKKLQQKEEQLLGEEPEKRRRQE 985
Query: 594 QENKRRMGDRLSHERHQF---QRDKEATQELIEDLRK----QLEHLQLLKLEAEQRRGRS 646
+E K R + L E Q +R+K QE RK Q E QLL+ E E+RR
Sbjct: 986 REKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRR--- 1042
Query: 647 SSMGLQEYHSRAR-ESELEQEVRRLKQDNRNLKEQNE 682
LQE + R E EL+QE +L + R + + E
Sbjct: 1043 ----LQERERQYREEEELQQEEEQLLGEERETRRRQE 1075
Score = 55.5 bits (132), Expect = 2e-07
Identities = 64/266 (24%), Positives = 114/266 (42%), Gaps = 57/266 (21%)
Query: 470 ERRVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMV-------LEE 522
ERR +L ++ EQ + ++E +L R + ++ +EQE R +++ LE+
Sbjct: 501 ERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQ 560
Query: 523 TRRQKELLCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKANIERLEEE------- 575
RR++ L + E + ++ + R QQ + E R + +ERLE+E
Sbjct: 561 ERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRL 620
Query: 576 KQKLLDEIESLTLRLSEEQENKR-----------------------RMGDRLSHERHQFQ 612
K++ +E L SEEQE +R R+ RL E + +
Sbjct: 621 KREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEER 680
Query: 613 RDKEATQELIEDLRKQLEHL-----QLLKLEAEQRRGRSSSMGL----------QEYHSR 657
R++E +E E R++++ L+ EA+ R+ + S QE R
Sbjct: 681 REQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRR 740
Query: 658 ARESELEQEVRRLKQDNRNLKEQNEE 683
RESEL+ + ++ R ++Q EE
Sbjct: 741 RRESELQWQ-----EEERAHRQQQEE 761
Score = 54.3 bits (129), Expect = 4e-07
Identities = 74/255 (29%), Positives = 108/255 (42%), Gaps = 36/255 (14%)
Query: 454 LMEGPEEDIADKVVFLER-RVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQE 512
L EG E+ + + ER R E+ E+ + QE QL R LE + +E+E
Sbjct: 1676 LQEGEEQQLRRQ----ERDRKFREEEQQLRRQERERKFLQEEQQL--RRQELERKFREEE 1729
Query: 513 LRACEMVLEETRRQKELLCKMEREK-SIEIENLQTRLQQLDE------------ENSELR 559
E E+ RRQ+ +E E+ E E Q R Q+ D E +LR
Sbjct: 1730 QLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLR 1789
Query: 560 SCTPCLKANIE---RLEEEKQKLLDEIESLTLRLSEEQENKRRMGDRLSHERHQFQRDKE 616
S K E R E E+Q+L + R EEQ RL ER + R +E
Sbjct: 1790 SQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEE 1849
Query: 617 --ATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARESELEQEVRRLKQDN 674
ATQE K Q L E EQ+R + L+E H R ++ E EQ R++ +
Sbjct: 1850 QFATQE------KSRREEQELWQEEEQKRRQERERKLREEHIRRQQKE-EQRHRQVGE-- 1900
Query: 675 RNLKEQNEELNGQII 689
+K Q + +G+++
Sbjct: 1901 --IKSQEGKGHGRLL 1913
Score = 53.9 bits (128), Expect = 5e-07
Identities = 69/281 (24%), Positives = 118/281 (41%), Gaps = 48/281 (17%)
Query: 470 ERRVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKEL 529
ERR +L ++ EQ R R++ L+ + ++ +EQ+LR ++ RR+++L
Sbjct: 371 ERREQQLRREQQLRREQQLR-REQQLRREQQLRREQQLRREQQLRR----EQQLRREQQL 425
Query: 530 LCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKL---------- 579
+ E E+ + + R Q+L E E R + ER E+E++K
Sbjct: 426 RREQEEERHEQKHEQERREQRLKREQEERRDWLK-REEETERHEQERRKQQLKRDQEEER 484
Query: 580 ------LDEIESLTLRLSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQ 633
L+E E + EQ+ +R E + QR K +E E L+++L Q
Sbjct: 485 RERWLKLEEEERREQQERREQQLRR------EQEERREQRLKRQEEE--ERLQQRLRSEQ 536
Query: 634 LLKLEAEQRRGRSSSMGLQEYHSRARESELEQEVRRLKQDNRNLKEQNEELNGQIITLSI 693
L+ E E+RR ++ R E LEQE R + LK + EE Q++
Sbjct: 537 QLRREQEERR--------EQLLKREEEKRLEQERR-----EQRLKREQEERRDQLLKREE 583
Query: 694 QGAKSLFSTAFSESL-----AAEISSVSRDELMEAIQKQEE 729
+ + E L E+ + ++E E K+EE
Sbjct: 584 ERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREE 624
Score = 53.9 bits (128), Expect = 5e-07
Identities = 62/237 (26%), Positives = 105/237 (44%), Gaps = 23/237 (9%)
Query: 468 FLERRVLELEKDTAATGEQHSRLRQENLQLVHRANAL---EEQLKEQELRACEMVLEETR 524
+ E ++ E++ E R RQE + L EEQL +E E
Sbjct: 1140 YREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQY 1199
Query: 525 RQKELLCKMEREKSIEIENLQTRLQ---QLDEENSELRSCTPCLKANIERLEEEKQKLLD 581
R++E L + +R++ E+ ++ L+ + ++EN+ + C E+ + + L
Sbjct: 1200 REEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLR 1259
Query: 582 EIES---LTLRLSEEQEN-----KRRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQ 633
+ +S L L E+QE +RR R H + Q ++E +E RK E Q
Sbjct: 1260 DRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQ 1319
Query: 634 LLKLEAEQRRGRSSSMGLQEYHSRARESE---LEQEVRRLKQDNRNLKEQNEELNGQ 687
LL+ E E++R R QE + RE E E+E + L++ R+ K + EEL Q
Sbjct: 1320 LLREEREEKRRR------QETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQ 1370
Score = 53.5 bits (127), Expect = 7e-07
Identities = 69/250 (27%), Positives = 117/250 (46%), Gaps = 35/250 (14%)
Query: 453 ELMEGPEEDIADKVVFLERRVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQE 512
+L EE+ ++ ERR L+++ E+ L++E H ++QLK +
Sbjct: 424 QLRREQEEERHEQKHEQERREQRLKREQE---ERRDWLKREEETERHEQERRKQQLKRDQ 480
Query: 513 LRACEMVLEETRRQKELLCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKANIERL 572
EE RR++ L K+E E+ E + + R QQL E E R + ERL
Sbjct: 481 --------EEERRERWL--KLEEEERREQQ--ERREQQLRREQEERREQRLKRQEEEERL 528
Query: 573 EEE---KQKLLDEIESLTLRLSEEQENKR----RMGDRLSHERHQ-----FQRDKEATQE 620
++ +Q+L E E +L + +E KR R RL E+ + +R++E Q+
Sbjct: 529 QQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQ 588
Query: 621 LI-----EDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRAR--ESELEQEVRRLKQD 673
+ E L ++L+ ++ +LE E+RR + E R + +SE EQE RR +Q
Sbjct: 589 RLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSE-EQEERRQQQL 647
Query: 674 NRNLKEQNEE 683
R +E+ E+
Sbjct: 648 RREQQERREQ 657
Score = 53.5 bits (127), Expect = 7e-07
Identities = 71/275 (25%), Positives = 119/275 (43%), Gaps = 46/275 (16%)
Query: 419 LTPSPTKRLSSKKVARYLHQSGALTMEALEDPSPELMEGPEEDIADKVVFLERRVLELEK 478
L P KR ++ +Y + E L+ +L+ E +RR E E+
Sbjct: 974 LGEEPEKRRRQEREKKYREE------EELQQEEEQLLREERE---------KRRRQEWER 1018
Query: 479 DTAATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELLCKMERE-- 536
E L+QE QL+ R + +L+E+E + E EE ++++E L ERE
Sbjct: 1019 QYRKKDE----LQQEEEQLL-REEREKRRLQERERQYREE--EELQQEEEQLLGEERETR 1071
Query: 537 KSIEIENLQTRLQQLDEENSELRSCTPCLKANIERLEE--EKQKLLDEIESLTLRLSEEQ 594
+ E+E + ++L +E +L P + ER + E+++L E E L L EE+
Sbjct: 1072 RRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQL---LREER 1128
Query: 595 ENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEY 654
E +RR +E ++ E+ Q E QLL+ E E+RR + +E
Sbjct: 1129 EKRRR---------------QELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREE 1173
Query: 655 HSRARESE--LEQEVRRLKQDNRNLKEQNEELNGQ 687
+E E L +E + +Q+ + EEL Q
Sbjct: 1174 EELQQEEEQLLREEQEKRRQERERQYREEEELQRQ 1208
Score = 52.8 bits (125), Expect = 1e-06
Identities = 48/220 (21%), Positives = 99/220 (45%), Gaps = 25/220 (11%)
Query: 470 ERRVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKEL 529
ER+ LE E+ Q L++E Q ++++ R E + +E R+++
Sbjct: 1514 ERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQE--REEQQ 1571
Query: 530 LCKMEREKSIEIENLQTRLQQLD----EENSELRSCTPCLKANIERLEEEKQKLLDEIES 585
L + ER++ +E + R Q+ + E+ +LR + ++L +E+ + E E
Sbjct: 1572 LSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRR-----QEGQQQLRQERDRKFREDEQ 1626
Query: 586 LTLRLSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQ---R 642
L E+Q +++ + E Q +R ++ +QL H + K E+ +
Sbjct: 1627 LLQEREEQQLHRQERDRKFLEEEPQLRR---------QEREQQLRHDRDRKFREEEQLLQ 1677
Query: 643 RGRSSSMGLQEYHSRARESELEQEVRRLKQDNRNLKEQNE 682
G + QE + RE EQ++RR +++ + L+E+ +
Sbjct: 1678 EGEEQQLRRQERDRKFREE--EQQLRRQERERKFLQEEQQ 1715
Score = 52.4 bits (124), Expect = 2e-06
Identities = 55/215 (25%), Positives = 94/215 (43%), Gaps = 25/215 (11%)
Query: 485 EQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELLCKMEREKSIEIENL 544
EQ R ++ + + L Q +EQ+LR + R +++ L + ER++ E
Sbjct: 1380 EQRLRRQERERKFLKEEQQLRCQEREQQLRQDRD--RKFREEEQQLSRQERDRKFREEEQ 1437
Query: 545 QTRLQQLD----EENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLRLSE------EQ 594
Q R Q+ + EE +LR R E+++LL E E L E E+
Sbjct: 1438 QVRRQERERKFLEEEQQLRQ-------ERHRKFREEEQLLQEREEQQLHRQERDRKFLEE 1490
Query: 595 ENKRRMGDRLSHERHQFQRDKEATQELIED---LRKQLEHLQLLKLEAEQRRGRSSSMGL 651
E + R +R R Q R +E ++ +E+ L +Q + L+ E + RR
Sbjct: 1491 EQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRR 1550
Query: 652 QEYHSRARESE---LEQEVRRLKQDNRNLKEQNEE 683
Q+ + RE E E+E ++L + R+ K + EE
Sbjct: 1551 QDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEE 1585
Score = 50.4 bits (119), Expect = 6e-06
Identities = 56/233 (24%), Positives = 103/233 (44%), Gaps = 23/233 (9%)
Query: 472 RVLELEKDTAATGEQHSRLRQENLQLVHRANALE-EQLKEQELRACEMVLEETRRQKELL 530
R LE+ EQ + ++ QL + + Q ++++ R E +L+E R+++ L
Sbjct: 1579 RKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQE--REEQQL 1636
Query: 531 CKMEREKSIEIENLQTRLQQLDEE-----NSELRSCTPCLKANIE---RLEEEKQKLLDE 582
+ ER++ E Q R Q+ +++ + + R L+ E R +E +K +E
Sbjct: 1637 HRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREE 1696
Query: 583 IESLTLR------LSEEQENKRRMGDRLSHERHQFQRDKEATQ-ELIEDLRKQLEHLQLL 635
+ L + L EEQ+ +R+ +R E Q +++ E Q E RK LE QL
Sbjct: 1697 EQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLR 1756
Query: 636 KLEAEQRRGRSSSMGLQEYHSRARESELEQEVRRLKQDNR-----NLKEQNEE 683
EQ+ R + R+ EQ++R + D + L+++ EE
Sbjct: 1757 PEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREE 1809
Score = 50.4 bits (119), Expect = 6e-06
Identities = 63/249 (25%), Positives = 104/249 (41%), Gaps = 33/249 (13%)
Query: 470 ERRVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKEL 529
+R+ LE E+ E+ +LR + + L ++ +EQ+LR E + R +++
Sbjct: 1642 DRKFLE-EEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERD-RKFREEEQQ 1699
Query: 530 LCKMEREKSIEIENLQTRLQQLDE---ENSELRSCTP------------CLKANIERLEE 574
L + ERE+ E Q R Q+L+ E +LR T L+ R E
Sbjct: 1700 LRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPER 1759
Query: 575 EKQKLLDEIESLTLRLS-------EEQENKRRMGDRLSHERHQFQRDKE----ATQELIE 623
E+Q+L + R EEQ+ + + DR E Q ++++E Q+
Sbjct: 1760 EEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDG 1819
Query: 624 DLRKQLEHLQLLKLEAEQRRGRSSSMGLQEY-----HSRARESELEQEVRRLKQDNRNLK 678
R + E LQL + E R+ R +E SR E EL QE + ++ R K
Sbjct: 1820 KYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERK 1879
Query: 679 EQNEELNGQ 687
+ E + Q
Sbjct: 1880 LREEHIRRQ 1888
Score = 50.1 bits (118), Expect = 8e-06
Identities = 51/216 (23%), Positives = 94/216 (43%), Gaps = 21/216 (9%)
Query: 485 EQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELLCKMEREKSIEIENL 544
E R + QL Q ++++ R E++ +Q+ L + + + E+
Sbjct: 117 EDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQ 176
Query: 545 QTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLRLSEEQENKRR-MGDR 603
+ Q+ +E +E C E +E+Q E+ L + EE++ +RR DR
Sbjct: 177 RQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDR 236
Query: 604 LSHERHQ---------FQRDKEATQELIEDLRKQL--EHLQLLKLEAEQ-RRGRSSSMGL 651
+ E + ++++E QE +++L E QL KLE ++ RR R
Sbjct: 237 VFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRER------ 290
Query: 652 QEYHSRARESELEQEVRRLKQDNRNLKEQNEELNGQ 687
QE + + EQ++RR +++ R +EQ EE Q
Sbjct: 291 QEEEQQQQRLRREQQLRRKQEEER--REQQEERREQ 324
Score = 50.1 bits (118), Expect = 8e-06
Identities = 51/203 (25%), Positives = 86/203 (42%), Gaps = 16/203 (7%)
Query: 489 RLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELLCKMEREKSIEIENLQTRL 548
R RQ L H +E+ +EQE R + +++L + ++E Q
Sbjct: 1259 RDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEK 1318
Query: 549 QQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLR-------LSEEQENKRRMG 601
Q L EE E R + +R E+++LL E E LR EE+ + G
Sbjct: 1319 QLLREEREEKRR-----RQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQG 1373
Query: 602 DRLSHERHQFQRDKEATQELIED--LRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRAR 659
+ E + +R + + L E+ LR Q QL + + R + QE + R
Sbjct: 1374 RKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFR 1433
Query: 660 ESELEQEVRRLKQDNRNLKEQNE 682
E E Q+VRR +++ + L+E+ +
Sbjct: 1434 EEE--QQVRRQERERKFLEEEQQ 1454
Score = 48.9 bits (115), Expect = 2e-05
Identities = 57/221 (25%), Positives = 104/221 (47%), Gaps = 12/221 (5%)
Query: 470 ERRVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKEL 529
E+ + E E+ E+ + +E QL R + + +EQELR+ E + +++L
Sbjct: 1467 EQLLQEREEQQLHRQERDRKFLEEEQQL--RRQERDRKFREQELRSQEPERKFLEEEQQL 1524
Query: 530 LCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLR 589
+ +R++ E Q R Q+ ++ + R + + R E E+Q+L + R
Sbjct: 1525 H-RQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQL-RQEREEQQLSRQERDRKFR 1582
Query: 590 LSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDL-RKQLEHLQLLKLEAEQRRGRSS- 647
L EEQ+ +R+ +R E Q R +E Q+L ++ RK E QLL+ EQ+ R
Sbjct: 1583 L-EEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQER 1641
Query: 648 SMGLQEYHSRARESELEQEV-----RRLKQDNRNLKEQNEE 683
E + R E EQ++ R+ +++ + L+E E+
Sbjct: 1642 DRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQ 1682
Score = 42.7 bits (99), Expect = 0.001
Identities = 51/210 (24%), Positives = 89/210 (42%), Gaps = 27/210 (12%)
Query: 485 EQHSRLRQENLQLVHRANALEEQLKEQELRACE---MVLEETRRQKELLC-----KMERE 536
E+ R R+ LQ A +Q +E++ R E++ R ++ L + +RE
Sbjct: 736 EEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRE 795
Query: 537 KSIEIENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLRLSEEQEN 596
+ + E Q R Q+ E E K R E++K L +E EE++
Sbjct: 796 RQLRAEERQQREQRFLPEEEE--------KEQRRRQRREREKELQFLE-------EEEQL 840
Query: 597 KRR-MGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYH 655
+RR +L E Q D+E + E R Q QL + +R + LQE
Sbjct: 841 QRRERAQQLQEEEDGLQEDQERRRSQ-EQRRDQKWRWQLEEERKRRRHTLYAKPALQEQL 899
Query: 656 SRARE--SELEQEVRRLKQDNRNLKEQNEE 683
+ ++ E E+E++R +++ R +EQ +
Sbjct: 900 RKEQQLLQEEEEELQREEREKRRRQEQERQ 929
Score = 42.7 bits (99), Expect = 0.001
Identities = 68/271 (25%), Positives = 112/271 (41%), Gaps = 41/271 (15%)
Query: 445 EALEDPSPELMEGPEEDIADKVV--FLERRVLELEKDTAATGEQHSRLRQENLQLVHRAN 502
E ++ L E PE+ ++ + E L+ E++ EQ R RQE +
Sbjct: 1145 EVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKR-RQERERQYREEE 1203
Query: 503 ALEEQLKEQELR----------ACEMVLEETRRQKELLCK-MEREKSIEIENLQTRLQQL 551
L+ Q ++Q R E E R ++ CK E E+ ++E+ Q R +Q
Sbjct: 1204 ELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQS 1263
Query: 552 DEENSELRSCTPCLKANIERLEEEKQKLLDEI-----ESLTLRLSEEQENKRRMGDRLSH 606
++ L L ER E++++ + E L E++E KRR DR S
Sbjct: 1264 QQDLQHL------LGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRR--DRKSQ 1315
Query: 607 ERHQFQRD-KEATQELIEDLRKQLEHLQLLKLEAEQ--------RRGRSSSMGLQEYHSR 657
E Q R+ +E + E RK E QLL+ EQ R+ R + QE +
Sbjct: 1316 EEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRK 1375
Query: 658 ARESEL-----EQEVRRLKQDNRNLKEQNEE 683
E E E+E + LK++ + ++ E+
Sbjct: 1376 FLEEEQRLRRQERERKFLKEEQQLRCQEREQ 1406
>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
Length = 1745
Score = 66.2 bits (160), Expect = 1e-10
Identities = 65/214 (30%), Positives = 82/214 (38%), Gaps = 27/214 (12%)
Query: 7 ASPPGSE-PPGPDPEPG--GPDG----------PGAAQLAPGPAELRLGAPVGGPDPQSP 53
A PPG + PPG D G GP G PG + + P E VGGP P
Sbjct: 1240 AGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGA 1299
Query: 54 GLDEPAPGAAADGGARWSAG--PAPGLEGGPRDPGPSAPPPRSGPRGQLASPDAPGPGPR 111
+ APG G G G +G +PGP PP R+GP G P GP
Sbjct: 1300 SGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGL 1359
Query: 112 SEAPLPELDPLFSWTEEPEECGPAS--CPESAPFRLQGSSSSHRARGEVDVFSPF-PAPT 168
P P +P P + GP P P L+G + +G + + P
Sbjct: 1360 RGIPGPVGEP--GLLGAPGQMGPPGPLGPSGLP-GLKGDTGPKGEKGHIGLIGLIGPPGE 1416
Query: 169 AGELALEQGPG--SPPQPSDLSQTHPLPSEPVGS 200
AGE + PG PP P + P P P+GS
Sbjct: 1417 AGEKGDQGLPGVQGPPGP----KGDPGPPGPIGS 1446
Score = 50.8 bits (120), Expect = 5e-06
Identities = 46/150 (30%), Positives = 58/150 (38%), Gaps = 38/150 (25%)
Query: 5 PPASPPGSEPPGPDPEPGGPDGPGA-AQLA-------PGPAELRLG--------APVGG- 47
PP P PPG + G P PG +L PGPA + LG P+G
Sbjct: 876 PPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGV-LGPQGKTGEVGPLGER 934
Query: 48 --PDPQSPGLDEPAPGAAADGGARWSAGPA--------------PGLEGGPRDPGPSAPP 91
P P P ++ PG GA+ GP PG +GGP DPGP+
Sbjct: 935 GPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLK 994
Query: 92 PRSGPRGQLASPDAPGP----GPRSEAPLP 117
GP G + + +PG GP LP
Sbjct: 995 GDKGPPGPVGANGSPGERGPLGPAGGIGLP 1024
Score = 49.3 bits (116), Expect = 1e-05
Identities = 64/219 (29%), Positives = 73/219 (33%), Gaps = 26/219 (11%)
Query: 6 PASPPGSEPPGPDPEPGGPDGPG----AAQLAPGPAELRLGAPVGGPDPQSPGLDEPAPG 61
P G PPG EPG P PG + + E GA G P P P PG
Sbjct: 1288 PGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAK-GEPGPDGP------PG 1340
Query: 62 AAADGGARWSAGPAPGLEGGPRDPGPSAPPPRSGPRGQLASPDAPGP----------GPR 111
GAR G G EG PGP P G GQ+ P GP GP+
Sbjct: 1341 RTGPMGARGPPGRV-GPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPK 1399
Query: 112 SEAPLPELDPLFSWTEEPEECGPASCP-ESAPFRLQGSSSSHRARGEVDVFSPFPAPTAG 170
E L L E E G P P +G G + P P AG
Sbjct: 1400 GEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLG--HPGPPGVAG 1457
Query: 171 ELALEQGPGSPPQPSDLSQTHPL-PSEPVGSQEDGPRLR 208
L + GSP T P P P G+ + LR
Sbjct: 1458 PLGQKGSKGSPGSMGPRGDTGPAGPPGPPGAPAELHGLR 1496
Score = 48.1 bits (113), Expect = 3e-05
Identities = 56/187 (29%), Positives = 67/187 (35%), Gaps = 34/187 (18%)
Query: 9 PPGSEP-PGPDPEPG--GPDGPGAAQLAPGPAELRLGAPVGGPDPQSPGLDEPAPGAAAD 65
PPG + PGP E G G G APGP PQ P E PG
Sbjct: 1146 PPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPR-----------GPQGPTGSEGTPGLPGG 1194
Query: 66 GGARWSAGPAPGLEGGPRDPGPSAPPPRSGPRGQLASPDAPGP----GPRSEAPLPELDP 121
G + G G G DPGP P GP+G + GP GP + P D
Sbjct: 1195 VGQPGAVGEK-GERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDG 1253
Query: 122 L---FSWTEEPEECGPASCPESAPFRLQGSSSSHRARGEV-DVFSPFPAPTAGELALEQG 177
T P + GP P + G S +G+ DV P P +GE
Sbjct: 1254 AKGSVGPTGLPGDLGPPGDP-----GVSGIDGSPGEKGDPGDVGGPGPPGASGE------ 1302
Query: 178 PGSPPQP 184
PG+P P
Sbjct: 1303 PGAPGPP 1309
Score = 48.1 bits (113), Expect = 3e-05
Identities = 64/229 (27%), Positives = 74/229 (32%), Gaps = 53/229 (23%)
Query: 6 PASPPGSEPPGPDPEPGGPDGPGAAQLAPGPAELR--LGAP--VGGPDPQSPGLDEPAPG 61
P PPG P P G GP + PGP LGAP +G P P P PG
Sbjct: 1335 PDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPS---GLPG 1391
Query: 62 AAADGGARWSAGPA-----------------PGLEGGPRDPGPSAPPPRSGPRGQLASPD 104
D G + G GL G PGP P GP G L P
Sbjct: 1392 LKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPG 1451
Query: 105 APG-PGPRSEAPLPELDPLFSWTEEPEECGPASCPESAPFRLQGSSSSHRARGEVDVFSP 163
PG GP + + GP P AP L G R F P
Sbjct: 1452 PPGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPG-PPGAPAELHGLRRRRR-------FVP 1503
Query: 164 FPAP-------------TAGELALEQ---GPGSPPQPS----DLSQTHP 192
P P T+ L LEQ PG+ +P +L + HP
Sbjct: 1504 VPLPVVEGGLEEVLASLTSLSLELEQLRRPPGTAERPGLVCHELHRNHP 1552
Score = 47.8 bits (112), Expect = 4e-05
Identities = 45/139 (32%), Positives = 51/139 (36%), Gaps = 43/139 (30%)
Query: 14 PPGPDPEPG--GPDGPGAAQLAPGPAELRLGAPVGGPDPQS-PGLD--EPAPGAAADGGA 68
PPG D E G GP GP PGP L LG P G P P PG+ + APGA + G
Sbjct: 576 PPGEDGERGAEGPPGPTGQAGEPGPRGL-LG-PRGSPGPTGRPGVTGIDGAPGAKGNVGP 633
Query: 69 RWSAGPA-----------------------------PGLEGGPRDPGPSAPPPRSGPRGQ 99
GP PG+ G P GP P GP G+
Sbjct: 634 PGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGE 693
Query: 100 LASPDAPG-------PGPR 111
+ PG PGPR
Sbjct: 694 KGAQGPPGSAGPPGYPGPR 712
Score = 47.4 bits (111), Expect = 5e-05
Identities = 62/219 (28%), Positives = 74/219 (33%), Gaps = 34/219 (15%)
Query: 6 PASPPGSEPPGPDPEPG--GPDGPGAAQLAPGPAELRLGAPVGGPDPQSPGLDEPAPGAA 63
P G PGP G GP GP A +PG E P GG E G A
Sbjct: 979 PGPKGGPGDPGPTGLKGDKGPPGPVGANGSPG--ERGPLGPAGGIGLPGQSGSEGPVGPA 1036
Query: 64 ADGGARWSAGP--APGLEGGPRDPGPSAPPPRSGPRGQLASP-DAPGPGPR-SEAPLPEL 119
G+R GP G +G P GP PP +GP G+ D PG + S+ +
Sbjct: 1037 GKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDA 1096
Query: 120 DPLFSWTEEPEECGPASCP----------ESAPFRLQGSSSSHRARGEVDVFSPFPAPTA 169
P +P GPA P P L G RG V V P
Sbjct: 1097 GP----PGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGP-----P 1147
Query: 170 GELALEQGPGSPPQPSDLSQTHPL-------PSEPVGSQ 201
G L PG + D+ P P P GS+
Sbjct: 1148 GLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSE 1186
Score = 46.2 bits (108), Expect = 1e-04
Identities = 58/214 (27%), Positives = 76/214 (35%), Gaps = 51/214 (23%)
Query: 5 PPASP-----PGSEPPGPDPEPGGPDGPGAAQLAPGPAELRLGAPVGGPDPQ-------S 52
PP +P PGS+ P P GP G AQ PG A P G P P+ +
Sbjct: 666 PPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSA-----GPPGYPGPRGVKGTSGN 720
Query: 53 PGLDEPAPGAAADG--GARWSAGPAPGLEGGPRDPGP------------------SAPPP 92
GL DG G + G G +G P PGP PP
Sbjct: 721 RGLQGEKGEKGEDGFPGFKGDVG-LKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPG 779
Query: 93 RSGPRGQLASPDAPG----PGPRSEAPLP-ELDPLFSWTEEPEECGPASCPESAPFRLQG 147
+G +G+L P PG PGP+ P L P+ + + P E P +G
Sbjct: 780 SAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRG 839
Query: 148 SSSSHRARGEVDVFSPFPAPTAGELALEQGPGSP 181
A G+ P P G++ + PG P
Sbjct: 840 ERGQPGATGQ-------PGP-KGDVGQDGAPGIP 865
Score = 45.8 bits (107), Expect = 1e-04
Identities = 63/209 (30%), Positives = 78/209 (37%), Gaps = 42/209 (20%)
Query: 11 GSEPP-GPDPEPG-----GPDGPGAAQLAPGPAELRLGAPVGGPDPQSPGLDEPAPGAAA 64
GSE P GP + G GP GP PGP P+G P P +E G
Sbjct: 1028 GSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPL-----GPLGPPGAAGPSGEE---GDKG 1079
Query: 65 DGGARWSAGPAPGLEGGPRDPGPSAPPPRSGPRGQLASPDAPG-PGPRSEAPLPELDPLF 123
D GA PG +G D G + PP + G RG P PG G + P L
Sbjct: 1080 DVGA-------PGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGL---- 1128
Query: 124 SWTEEPEECGPASCPESAPFRLQGSSSSHRARGEV-DVFS--PFPAPTAGELALEQGPGS 180
+ ++ ++ P LQG +GEV DV S P AP GP
Sbjct: 1129 -FGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAP---------GPRG 1178
Query: 181 PPQPSDLSQTHPLP---SEPVGSQEDGPR 206
P P+ T LP +P E G R
Sbjct: 1179 PQGPTGSEGTPGLPGGVGQPGAVGEKGER 1207
Score = 45.1 bits (105), Expect = 2e-04
Identities = 64/221 (28%), Positives = 75/221 (33%), Gaps = 45/221 (20%)
Query: 14 PPGPDPEPG--GPDGPGAAQLAPGPAELR--LGAP--VGGPDPQSPGLDEPAPGAAADGG 67
P GP E G G G + GP R G P G P P+ + APG + G
Sbjct: 810 PLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKG 869
Query: 68 ARWSAGPAPGLEGGPRDPGPSAPPPRSGPRGQLASPDAPG----------PGPRS----E 113
PGL+G P PGP PP G G+ P G PGP +
Sbjct: 870 L-------PGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQ 922
Query: 114 APLPELDPLFSWTEEPEECGPASCP-ESAPFRLQGSSSSHRARGEVDVFSPFPAPTAGEL 172
E+ PL E GP P L G A+GE+ P P G
Sbjct: 923 GKTGEVGPL-------GERGPPGPPGPPGEQGLPGLEGREGAKGELG--PPGPLGKEGPA 973
Query: 173 ALEQGPGSPPQPSDLSQT----HPLPSEPVGSQ----EDGP 205
L PG P D T P PVG+ E GP
Sbjct: 974 GLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGP 1014
Score = 43.9 bits (102), Expect = 6e-04
Identities = 62/217 (28%), Positives = 72/217 (33%), Gaps = 35/217 (16%)
Query: 6 PASPPGSEPPGPDPEPG--GPDGPGAAQLAPGPAEL--RLGAPVGGPDPQSPGLDEPA-- 59
P PG PG E G GP GP Q GP ++G P PG P
Sbjct: 492 PVGLPGH--PGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGD 549
Query: 60 ------PGAAADGGARWSAG----PAP----GLEGGPRDPGPSAPPPRSGPRGQLASPDA 105
PG + G R G P P G G PGP+ GPRG L +
Sbjct: 550 RGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGS 609
Query: 106 PGPGPRSEAPLPELDPLFSWTEEPEECGPASCPESAPFRLQGSSSSHRARGEVDVFSPFP 165
PGP R P + + GP E P QG+ S G +
Sbjct: 610 PGPTGR-----PGVTGIDGAPGAKGNVGPPG--EPGPPGQQGNHGSQGLPGPQGLIG--- 659
Query: 166 APTAGELALEQGPGSPPQP-SDLSQTHPLPSEPVGSQ 201
T GE PG P P SD HP P G +
Sbjct: 660 --TPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEK 694
Score = 35.0 bits (79), Expect = 0.26
Identities = 30/93 (32%), Positives = 34/93 (36%), Gaps = 12/93 (12%)
Query: 60 PGAAADGGARWSAGPAPG--LEGGPRDPGPSAPPPRSGPRGQLASPDAPG-PGPRSEAPL 116
PGA G A G EG P PGP SGP G P PG PGP +
Sbjct: 370 PGAGEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGI 429
Query: 117 PELDPLFSWTEEPEECGPASCPESAPFRLQGSS 149
P +D + GP PF+ G S
Sbjct: 430 PGIDGI---------RGPPGTVIMMPFQFAGGS 453
Score = 35.0 bits (79), Expect = 0.26
Identities = 37/122 (30%), Positives = 44/122 (36%), Gaps = 19/122 (15%)
Query: 5 PPASPPG------SEPPGPDPEPGGPDGPGAAQL--APGPAELRLGAP----------VG 46
PP +P S PPGP PG P PG A L PG +R G P G
Sbjct: 393 PPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIR-GPPGTVIMMPFQFAG 451
Query: 47 GPDPQSPGLDEPAPGAAADGGARWSAGPAPGLEGGPRDPGPSAPPPRSGPRGQLASPDAP 106
G P + A A + S PG G PGP P G +G+ +
Sbjct: 452 GSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQ 511
Query: 107 GP 108
GP
Sbjct: 512 GP 513
Score = 33.1 bits (74), Expect = 0.98
Identities = 62/232 (26%), Positives = 76/232 (32%), Gaps = 34/232 (14%)
Query: 6 PASPPGSEPPG--PDPEPGGPDG----PGAAQLAPGPAELRL------GAPVGGPDPQSP 53
P+ PPG PPG DP P GP G PG + P + + G GP
Sbjct: 405 PSGPPG--PPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQ 462
Query: 54 GLDEPAPGAAADGGARWSAGPA-----PGLEGGPRDPGPSAPPPRSGPRGQ--LASPDAP 106
A + GP PG G P PG GP+G L P P
Sbjct: 463 QAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGP 522
Query: 107 GPGPRSEAPLPELDPLFSWTEEPEECGPASCPESAPFRLQGSSSSHRARGEV-DVFSPFP 165
PG + P D P + GP + L G RG+ V P P
Sbjct: 523 -PGRVGKMGRPGADGARGL---PGDTGPKG--DRGFDGLPGLPGEKGQRGDFGHVGQPGP 576
Query: 166 APTAGELALEQGPGSPPQPSDLSQTHPLPSEPVGSQ-EDGPRLRAVFDALDG 216
GE E PG Q + P P +G + GP R +DG
Sbjct: 577 PGEDGERGAEGPPGPTGQAGE-----PGPRGLLGPRGSPGPTGRPGVTGIDG 623
Score = 33.1 bits (74), Expect = 0.98
Identities = 38/137 (27%), Positives = 48/137 (35%), Gaps = 30/137 (21%)
Query: 3 SAPPASPPGSEPPGPDPEPGGPDGPGAAQLAPGPAELRL-----------GAPVGGPDPQ 51
S PP P PGP G P PG + P + + G PV Q
Sbjct: 406 SGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQ 465
Query: 52 SPGLDEPA----PGAAADGGARWSAGPA-----PGLEG-----GPRDP----GPSAPPPR 93
+ + + G G GP PGL+G GP+ P GP PP R
Sbjct: 466 AQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGR 525
Query: 94 SGPRGQLASPDAPG-PG 109
G G+ + A G PG
Sbjct: 526 VGKMGRPGADGARGLPG 542
>gi|111955084 5-azacytidine induced 1 isoform a [Homo sapiens]
Length = 1080
Score = 65.9 bits (159), Expect = 1e-10
Identities = 73/288 (25%), Positives = 130/288 (45%), Gaps = 30/288 (10%)
Query: 475 ELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELLCKME 534
+LE++ A G+Q ++ Q + +EQ Q+ R + + E ++E L +
Sbjct: 755 QLEREKEALGQQERERARQRFQ----QHLEQEQWALQQQR--QRLYSEVAEERERLGQQA 808
Query: 535 REKSIEIENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLRLSEEQ 594
+ E+E L+ QQL+E +S L T L+A E+ EE+++ ++E TL+ E
Sbjct: 809 ARQRAELEELR---QQLEESSSAL---TRALRAEFEKGREEQERR-HQMELNTLKQQLEL 861
Query: 595 ENKR-RMGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQE 653
E + G E R++E +E+ + K++E L + +LEA+ + S E
Sbjct: 862 ERQAWEAGRTRKEEAWLLNREQELREEIRKGRDKEIE-LVIHRLEADMALAKEESEKAAE 920
Query: 654 YHSRARESELEQEVRRLKQDNRNLKEQNEELNGQI-----ITLSIQGAKSLFSTAFSESL 708
+ + E E+ L+Q R L+E+ EL GQ+ L +QG A ++
Sbjct: 921 SRIKRLRDKYEAELSELEQSERKLQERCSELKGQLGEAEGENLRLQGLVRQKERALEDAQ 980
Query: 709 AA-EISSVSRDELMEAIQKQEEINFRLQDYIDRIIVAIMETNPSILEV 755
A E S R L + I+ Q++ DR+ + ET + E+
Sbjct: 981 AVNEQLSSERSNLAQVIR---------QEFEDRLAASEEETRQAKAEL 1019
Score = 49.7 bits (117), Expect = 1e-05
Identities = 64/255 (25%), Positives = 112/255 (43%), Gaps = 35/255 (13%)
Query: 425 KRLSSKKVARYLHQSGALTMEALEDPSPELMEGPEEDIADKVVFLE--RRVLELEKDTAA 482
+R +++ + L +S + AL E +G EE + L ++ LELE+
Sbjct: 811 QRAELEELRQQLEESSSALTRALR---AEFEKGREEQERRHQMELNTLKQQLELERQAWE 867
Query: 483 TGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELLCKMEREKSIEIE 542
G R R+E L++R L E++++ + E+V+ L K E EK+ E
Sbjct: 868 AG----RTRKEEAWLLNREQELREEIRKGRDKEIELVIHRLEADM-ALAKEESEKAAE-- 920
Query: 543 NLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLRLSE-EQENKRRMG 601
+R+++L ++ +A + LE+ ++KL + L +L E E EN R G
Sbjct: 921 ---SRIKRLRDK----------YEAELSELEQSERKLQERCSELKGQLGEAEGENLRLQG 967
Query: 602 DRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRA--- 658
L ++ + D +A E + R L Q+++ E E R S Q A
Sbjct: 968 --LVRQKERALEDAQAVNEQLSSERSNL--AQVIRQEFEDRLAASEEETRQAKAELATLQ 1023
Query: 659 --RESELEQEVRRLK 671
++ ELE+ RR+K
Sbjct: 1024 ARQQLELEEVHRRVK 1038
Score = 45.1 bits (105), Expect = 2e-04
Identities = 65/275 (23%), Positives = 106/275 (38%), Gaps = 43/275 (15%)
Query: 452 PELMEGPEEDIADKVVFLERRVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQ 511
PE GP E ++ + R LE+E+ A L Q+ R E+ L Q
Sbjct: 553 PEAGPGPLELGSEVSTSVMRLKLEVEEKKQAMLLLQRALAQQRDLTARRVKETEKALSRQ 612
Query: 512 ELRACEMVLEETRRQKELLCKMEREKSIEIENLQTRLQQLDEEN---------------- 555
R E +R + ++ +K + E + + +L +E+
Sbjct: 613 LQRQREHYEATIQRHLAFIDQLIEDKKVLSEKCEAVVAELKQEDQRCTERVAQAQAQHEL 672
Query: 556 -----SELRSCTPCLKANIERLEEEKQKLLDEIESLTLR------LSEEQENKRRMGDRL 604
EL S T KA E+ EK K + E+ L ++ ++ RR+ +
Sbjct: 673 EIKKLKELMSATE--KARREKWISEKTKKIKEVTVRGLEPEIQKLIARHKQEVRRL--KS 728
Query: 605 SHERHQFQRDKEATQELI---EDLRKQLEHLQLLKLEAEQRRGR--------SSSMGLQE 653
HE Q D+ A+Q + E+LR+QLE + + E+ R R LQ+
Sbjct: 729 LHEAELLQSDERASQRCLRQAEELREQLEREKEALGQQERERARQRFQQHLEQEQWALQQ 788
Query: 654 YHSRARESELEQEVRRLKQDNRNLKEQNEELNGQI 688
R SE+ +E RL Q + + EEL Q+
Sbjct: 789 QRQRL-YSEVAEERERLGQQAARQRAELEELRQQL 822
Score = 34.3 bits (77), Expect = 0.44
Identities = 44/160 (27%), Positives = 67/160 (41%), Gaps = 20/160 (12%)
Query: 422 SPTKRLSSKKVARY--LHQSGALTMEALEDPSPELMEGPEEDIA-DKVVFLERRVLELEK 478
S KRL K A L QS E + +L E E++ +V + R LE
Sbjct: 921 SRIKRLRDKYEAELSELEQSERKLQERCSELKGQLGEAEGENLRLQGLVRQKERALE--- 977
Query: 479 DTAATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELLCKMEREKS 538
D A EQ S R Q++ + E++L E EETR+ K L ++ +
Sbjct: 978 DAQAVNEQLSSERSNLAQVIRQE--FEDRLAASE--------EETRQAKAELATLQARQQ 1027
Query: 539 IEIE----NLQTRLQQLDEENSELRSCTPCLKANIERLEE 574
+E+E ++T L + +E S LR+ + LEE
Sbjct: 1028 LELEEVHRRVKTALARKEEAVSSLRTQHEAAVKRADHLEE 1067
>gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo
sapiens]
Length = 693
Score = 65.1 bits (157), Expect = 2e-10
Identities = 63/265 (23%), Positives = 122/265 (46%), Gaps = 36/265 (13%)
Query: 456 EGPEEDIADKVVFLERRVLELEKDTAATGEQ---------------HSRLRQ---ENLQL 497
E +D+A ++ + +R+ ELE+ A Q H RL+Q E L
Sbjct: 152 EEESKDLAGRLQYSLQRIQELERALCAVSTQQQEEDRSSSCREAVLHRRLQQTIKERALL 211
Query: 498 VHRANALEEQLKEQELRACEM---VLEETRRQKELLCKMERE-KSIEIENLQT--RLQQL 551
+ E LK+ +L E + E R +E + KM E ++++ E + R+Q+L
Sbjct: 212 NAHVTQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIHRIQEL 271
Query: 552 DEENSELRS--------CTPCLKANIERLEEEKQKLLDEIESLTLRLSEEQENKRRMGDR 603
+ SEL++ P + + +E+L++E + L E+E L +L + EN + +
Sbjct: 272 ERSLSELKNQMAKPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQALSLL 331
Query: 604 LSHERHQFQRDKEATQEL-IEDLRKQ---LEHLQLLKLEAEQRRGRSSSMGLQEYHSRAR 659
++ + Q +E +E ++ +R+Q E + L+ + + + + + QE R +
Sbjct: 332 SKEQKQRLQEQEEMLREQEVQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQ 391
Query: 660 ESELEQEVRRLKQDNRNLKEQNEEL 684
E L +E RL++ + L +Q E L
Sbjct: 392 EERLRKEEERLQKQEKRLWDQEERL 416
Score = 55.5 bits (132), Expect = 2e-07
Identities = 63/273 (23%), Positives = 120/273 (43%), Gaps = 28/273 (10%)
Query: 474 LELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELLCKM 533
++LE+D A + R R + + + + + LKE++ R + E R EL +M
Sbjct: 225 VQLERDEYAKHIKGERARWQ--ERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQM 282
Query: 534 EREKSIEIENLQTRLQQLDEENSELRSCTPCLKANIERL-----------EEEKQKLLDE 582
+ S+ + + ++QL +E LR L+ ++ +E+KQ+L ++
Sbjct: 283 AKPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQ 342
Query: 583 IESLTLRLSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQR 642
E L E++ + R +RL + + + ++ QE E LRKQ + +L ++
Sbjct: 343 EE----MLREQEVQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQ-----RLRKQEE 393
Query: 643 RGRSSSMGLQEYHSRARESE---LEQEVRRLKQDNRNLKEQNEELNGQII--TLSIQGAK 697
R R LQ+ R + E ++E R KQ+ R QN +L+ Q+ S +
Sbjct: 394 RLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLN 453
Query: 698 SLFSTAFS-ESLAAEISSVSRDELMEAIQKQEE 729
+ +A E E+ +E +EA +Q +
Sbjct: 454 NEKKSALQLEQQVKELQEKLDEEHLEAASQQNQ 486
Score = 55.1 bits (131), Expect = 2e-07
Identities = 50/231 (21%), Positives = 101/231 (43%), Gaps = 29/231 (12%)
Query: 451 SPELMEGPEEDIADKVVFLERRVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKE 510
+P + E + D+ L + V LE + E + L + + R EE L+E
Sbjct: 289 APPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLRE 348
Query: 511 QELRACEMVLEETRRQKELLCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKANIE 570
QE++ R++E LC+ + + LQ + ++L ++ LR L+ E
Sbjct: 349 QEVQRV--------REQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEE 400
Query: 571 RLEEEKQKLLDEIESLTLRLSEEQENKRRMGDRLS-HERHQFQRDKEATQELIEDLRKQL 629
RL++++++L D+ E RL +++E ++ +RL+ + H+ + Q EDL +
Sbjct: 401 RLQKQEKRLWDQEE----RLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNE- 455
Query: 630 EHLQLLKLEAEQRRGRSSSMGLQEYHSRARESELEQEVRRLKQDNRNLKEQ 680
+ S++ L++ +E E+ + Q N+ L+ Q
Sbjct: 456 ---------------KKSALQLEQQVKELQEKLDEEHLEAASQQNQQLETQ 491
Score = 36.2 bits (82), Expect = 0.12
Identities = 27/136 (19%), Positives = 62/136 (45%), Gaps = 7/136 (5%)
Query: 573 EEEKQKLLDEIESLTLRLSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHL 632
+ + Q+L +ES ++ +S+ EN + + HQ + K+ E+ + ++LE +
Sbjct: 68 DSQYQELAVALESSSVTISQLNENIESLKQQKKQVEHQLEEAKKTNNEIHKAQMERLETI 127
Query: 633 QLLKLEAEQRRGRSSSMGLQEYHSRARESELEQEVRRLKQDNRNLKEQNEELNGQIITLS 692
+L LE + + YH++ E+E + L + ++ +EL + +S
Sbjct: 128 NILTLE-------KADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQRIQELERALCAVS 180
Query: 693 IQGAKSLFSTAFSESL 708
Q + S++ E++
Sbjct: 181 TQQQEEDRSSSCREAV 196
>gi|41872583 Rho-associated, coiled-coil containing protein kinase 2
[Homo sapiens]
Length = 1388
Score = 64.7 bits (156), Expect = 3e-10
Identities = 84/317 (26%), Positives = 146/317 (46%), Gaps = 49/317 (15%)
Query: 455 MEGPEEDIADKVVFLERRVLELEKD-----TAATGEQHSRLRQENL--QLVHRANALEEQ 507
+E D+ DK LE L+LEK+ +A E+ R + L R LEE
Sbjct: 595 LESNNRDLQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGRICGLEED 654
Query: 508 LKEQELRACEMVLEETRRQKELLCKMEREKS-IEIE---NLQTRLQQLDEENSELRSCTP 563
LK ++ ++ LE+ R+ +E +E+EKS +EI+ L+ Q L++E +E ++
Sbjct: 655 LKNGKILLAKVELEK-RQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKA 713
Query: 564 CLKAN---IERLEEEKQKLLDEIESLTLRLSEEQENKRRMGDRLSHERHQ---FQRDKEA 617
L E +EE K + + E+E +L EE+ K+++ + L + D +
Sbjct: 714 RLADKNKIYESIEEAKSEAMKEMEK---KLLEERTLKQKVENLLLEAEKRCSLLDCDLKQ 770
Query: 618 TQELIEDLRKQLEHLQ------LLKLEAEQRR----GRSSSMGLQEYHS-RARESELEQE 666
+Q+ I +L KQ + L LK+E E ++ M Q+ ++ + E +L+QE
Sbjct: 771 SQQKINELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQE 830
Query: 667 VRRLKQDNRNLKEQNEEL-------NGQIITLSIQ-GAKSLFSTAFSESLAAEISSVSRD 718
L + NL++QN EL +GQ+ L Q A+ FST + +
Sbjct: 831 NNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVR--------- 881
Query: 719 ELMEAIQKQEEINFRLQ 735
EL E +++ ++ LQ
Sbjct: 882 ELKEECEEKTKLGKELQ 898
Score = 53.9 bits (128), Expect = 5e-07
Identities = 58/279 (20%), Positives = 123/279 (44%), Gaps = 40/279 (14%)
Query: 445 EALEDPSPELMEGPEEDIADKVVF---LERRVLELEKDTAATGEQHSRLRQENLQLVHRA 501
E++E+ E M+ E+ + ++ +E +LE EK + + +Q+ +L+ +
Sbjct: 723 ESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLKQK 782
Query: 502 NALEEQLKEQELRACEMVLEETRRQKELLCKMEREKSIEIENLQTRLQQLDEENSELRSC 561
+ L E ++ L+ + + Q +L KM+ + ++ L+ +QL +EN+ L
Sbjct: 783 DVLNEDVRNLTLKIEQETQKRCLTQNDL--KMQTQ---QVNTLKMSEKQLKQENNHLMEM 837
Query: 562 TPCLKANIERLEEEKQ-------KLLDEIE----------SLTLRLSEEQENKRRMGDRL 604
L+ L +E+Q +L D++E + L EE E K ++G L
Sbjct: 838 KMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKEL 897
Query: 605 SHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAE------QRRGRSSSMGLQEYHSRA 658
++ + Q ++++ +E + + QL + AE ++ + ++E +R
Sbjct: 898 QQKKQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARH 957
Query: 659 RE---------SELEQEVRRLKQDNRNLKEQNEELNGQI 688
++ + LE+ R L D NL + EELN ++
Sbjct: 958 KQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKL 996
Score = 46.6 bits (109), Expect = 9e-05
Identities = 50/239 (20%), Positives = 101/239 (42%), Gaps = 37/239 (15%)
Query: 450 PSPELMEGPEEDIADKVVFLERRVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLK 509
P P+ G + + E +L T SR +E+ ++ + LEE L
Sbjct: 398 PIPKAFVGNQLPFIGFTYYRENLLLSDSPSCRETDSIQSRKNEESQEIQKKLYTLEEHLS 457
Query: 510 EQELRACEMVLEETRRQKELLCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKANI 569
EM +E QK CK ++ TRL++ +E E + +++ +
Sbjct: 458 N------EMQAKEELEQK---CK----------SVNTRLEKTAKELEEEITLRKSVESAL 498
Query: 570 ERLEEEKQKLLDEIESLTLRLSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQL 629
+LE EK L + + E + KR + + D + ++ +EDL+K+
Sbjct: 499 RQLEREKALLQHKNAEYQRKADHEADKKRNL-----------ENDVNSLKDQLEDLKKRN 547
Query: 630 EHLQLLKLEAEQ-RRGRSSSMGLQEYHS------RARESELEQEVRRLKQDNRNLKEQN 681
++ Q+ + Q +R + L S R ++E +++++L+ +NR+L+++N
Sbjct: 548 QNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESNNRDLQDKN 606
Score = 36.2 bits (82), Expect = 0.12
Identities = 58/297 (19%), Positives = 119/297 (40%), Gaps = 44/297 (14%)
Query: 475 ELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKE-QELRACEMVLEETRRQKELLCKM 533
+L+++ E L ++N +L + Q+KE Q+ E + + K
Sbjct: 826 QLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKE 885
Query: 534 EREKSIEI-ENLQTRLQQLDEENSELRSCTPCL--KANIERLEE----------EKQKLL 580
E E+ ++ + LQ + Q+L +E L + KA+ E+L EK+K++
Sbjct: 886 ECEEKTKLGKELQQKKQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIM 945
Query: 581 DEIESLTLRLSEEQE--------------NKRRMGD--RLSHERHQFQRDKEATQELIED 624
E+E + +QE N+ D L++E+ + + QE +
Sbjct: 946 KELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLSR 1005
Query: 625 LRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARESELEQ--------EVRRLKQDNR- 675
L+ + +K + E++ ++ Q + A ++ +VRR +++NR
Sbjct: 1006 LKDEEISAAAIKAQFEKQLLTERTLKTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKENRK 1065
Query: 676 ---NLKEQNEELNGQIITLSIQGAKSLFSTAFSESLAAEISSV--SRDELMEAIQKQ 727
LK + E+L Q+I + + A + E+ S+D +E ++ Q
Sbjct: 1066 LHMELKSEREKLTQQMIKYQKELNEMQAQIAEESQIRIELQMTLDSKDSDIEQLRSQ 1122
Score = 35.0 bits (79), Expect = 0.26
Identities = 54/254 (21%), Positives = 110/254 (43%), Gaps = 39/254 (15%)
Query: 469 LERRVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQELR------ACEMVLEE 522
LER L+ A + + L + N+L++QL++ + R + E V +
Sbjct: 501 LEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQLEDLKKRNQNSQISTEKVNQL 560
Query: 523 TRRQKEL--LCKMEREKSIEIENLQT----RLQQLDEENSELRSCTPCLKANIERLEEE- 575
R+ E L + E + + + Q ++QQL+ N +L+ L+ +LE+E
Sbjct: 561 QRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESNNRDLQDKNCLLETAKLKLEKEF 620
Query: 576 ----------------KQKLLDEIESLTLRLSEEQENKRRMGDRLSHERHQFQR---DKE 616
+++++++ L E+ +N + + ++ E+ Q Q D E
Sbjct: 621 INLQSALESERRDRTHGSEIINDLQGRICGLEEDLKNGKILLAKVELEKRQLQERFTDLE 680
Query: 617 ATQELIE-DLRKQLEHLQLLKLEAEQRRGRSSSMGLQE----YHS-RARESELEQEVRRL 670
+ +E D+ QL+ +Q LE E+ +++ L + Y S +SE +E+ +
Sbjct: 681 KEKSNMEIDMTYQLKVIQ-QSLEQEEAEHKATKARLADKNKIYESIEEAKSEAMKEMEKK 739
Query: 671 KQDNRNLKEQNEEL 684
+ R LK++ E L
Sbjct: 740 LLEERTLKQKVENL 753
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 64.3 bits (155), Expect = 4e-10
Identities = 68/214 (31%), Positives = 82/214 (38%), Gaps = 34/214 (15%)
Query: 6 PASPPGSE-PPGPDPEPGGPDGPGAAQLAPGPAELRLGAPVGGPDPQSPGLDEPAPGAAA 64
PA PGS PG EPG P G AQ PGP + G+P G + G+ PGA
Sbjct: 355 PAGSPGSNGAPGQRGEPG-PQGHAGAQGPPGPPGIN-GSPGGKGEMGPAGI----PGAPG 408
Query: 65 DGGARWSAGPA-----PGLEGGPRDPGPSAPPPRSGPRGQLASPDAPG-PGPRSEAPLPE 118
GAR GPA PGL GG +PG + GPRG+ PG PG + E
Sbjct: 409 LMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGE----- 463
Query: 119 LDPLFSWTEEPEECG-PASCPESAPFRLQGSSSSHRARGEVDVFSPFPAP-------TAG 170
D EP G P + E +G + + GE AP AG
Sbjct: 464 -DGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAG 522
Query: 171 ELALEQGPGSPPQPSDLSQTHPLPSEPVGSQEDG 204
E + PG P +P P G DG
Sbjct: 523 EPGRDGVPGGPGM-------RGMPGSPGGPGSDG 549
Score = 64.3 bits (155), Expect = 4e-10
Identities = 72/214 (33%), Positives = 84/214 (39%), Gaps = 25/214 (11%)
Query: 3 SAPPASPPGSEPPGPDPEPGGPDGPGAAQLA-----PGPAEL-----RLGAPVGGPDPQS 52
+ PP P PGP G PGA L+ PGP L G P +P S
Sbjct: 959 AGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGS 1018
Query: 53 PGLD--EPAPGAAADGGARWSAGPAPGLEGGPRDPGPSAPPPRSGPRGQL--ASP-DAPG 107
GL + +PG D G S G APG G P PGP P +SG RG+ A P APG
Sbjct: 1019 DGLPGRDGSPGGKGDRGENGSPG-APGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPG 1077
Query: 108 PGPRSEAPLPELDPLFSWTEEPEECGPASCP--ESAPFRLQGSSSSHRARGEVDVFSPFP 165
P AP P+ P E E G A P S A + + SP P
Sbjct: 1078 PAGSRGAPGPQ-GPRGDKGETGER-GAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGP 1135
Query: 166 APTAGELALEQGPGSPPQPSDLSQTHPLPSEPVG 199
A G + GP PP D + HP P P G
Sbjct: 1136 AGPRGPV----GPSGPP-GKDGTSGHPGPIGPPG 1164
Score = 63.5 bits (153), Expect = 7e-10
Identities = 76/225 (33%), Positives = 86/225 (38%), Gaps = 49/225 (21%)
Query: 6 PASPPGSEPPGPDPEPGGPDGPGAAQLA-----PGPAELRLGAPVGGPDPQ-SPGLDEP- 58
PA PPG P G E G P GPGAA PGP G P G P P SPG D P
Sbjct: 850 PAGPPG--PQGVKGERGSPGGPGAAGFPGARGLPGPPGSN-GNP-GPPGPSGSPGKDGPP 905
Query: 59 -------APGAAADGGARWSAGP-----APGLEGGPRDPGPSAPPPRSGPRGQLASPDAP 106
APG+ G + AG +PG +G P PGP +G RG P P
Sbjct: 906 GPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMP 965
Query: 107 GP-------GPRSEAPLPELDPLFSWTEEPEECGPASCPESA-----PFRLQGSSSSHRA 154
GP G + E+ P + L P GP P A P R G+ S
Sbjct: 966 GPRGSPGPQGVKGESGKPGANGLSGERGPP---GPQGLPGLAGTAGEPGR-DGNPGSDGL 1021
Query: 155 RGEVDVFSPFPAPTAGELALEQGPGSPPQPSDLSQTHPLPSEPVG 199
G SP GE PG+P P HP P PVG
Sbjct: 1022 PGRDG--SPGGKGDRGE---NGSPGAPGAPG-----HPGPPGPVG 1056
Score = 62.8 bits (151), Expect = 1e-09
Identities = 68/217 (31%), Positives = 78/217 (35%), Gaps = 28/217 (12%)
Query: 6 PASPPGSE----PPGPDP-----EPGGPDGPGAAQLAPGPA--ELRLGAPVGGPDPQSPG 54
P P G + PPGP GGP G PGP GAP G D +PG
Sbjct: 622 PTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPG 681
Query: 55 LDEPAPGAAADGGARWSAGPAPGLEGGPRDPGPSAPPPRSGPRGQLASP------DAPGP 108
P PG A G R AGP PG EGG GP PP +G G P +PGP
Sbjct: 682 ERGP-PGLAGAPGLRGGAGP-PGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGP 739
Query: 109 -GPRSEAPLPELDPLFSWTEEPEECGPASCPESAPFRLQGSSSSHRARGEVDVFSPFPAP 167
G + E P D + GP P P G A G + P +P
Sbjct: 740 KGDKGEPGGPGADGVPGKDGPRGPTGPIGPP--GPAGQPGDKGEGGAPGLPGIAGPRGSP 797
Query: 168 TAGELALEQGPGSPPQPSDLSQTHPLPSEPVGSQEDG 204
E+G PP P+ EP G E G
Sbjct: 798 G------ERGETGPPGPAGFPGAPGQNGEPGGKGERG 828
Score = 59.7 bits (143), Expect = 1e-08
Identities = 68/237 (28%), Positives = 83/237 (35%), Gaps = 46/237 (19%)
Query: 6 PASPPGSE-PPGPDPEPGGPDGPGAAQLAPGP-AELRLGAP-----VGGPDPQSPGLDEP 58
PA P G+ PG D PGGP G GP ++ + G P G P P P
Sbjct: 514 PAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRG 573
Query: 59 APGAAADGGARWSAGPAPGL---EGGPRDPGPSAPPPRSGPRGQLASPDAPG-------- 107
PG G + + G APG GGP PGP PP ++G G P G
Sbjct: 574 QPGVMGFPGPKGNDG-APGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDT 632
Query: 108 --PGPRSEAPLPELDPLFSWTEEPEECGP---ASCP-------------ESAPFRLQGSS 149
PGP+ LP +P E GP A P E P L G+
Sbjct: 633 GPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAP 692
Query: 150 SSHRARGEVDVFSPFPAPTAGELALEQGPGSPPQPSDLSQTHPLPSEPVGSQEDGPR 206
G P P G+ A GP PP + +P E G GP+
Sbjct: 693 GLRGGAGP-------PGPEGGKGA--AGPPGPPGAAGTPGLQGMPGERGGLGSPGPK 740
Score = 59.7 bits (143), Expect = 1e-08
Identities = 66/235 (28%), Positives = 75/235 (31%), Gaps = 42/235 (17%)
Query: 9 PPGSE----PPGPDPEPGGPDGPGAAQLAPGPAE-----------LRLGAPVGGPDPQSP 53
PPG PGP + G P PG A P E LR GA GP+
Sbjct: 649 PPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKG 708
Query: 54 GLDEPA-PGAAADGGARWSAGPAPGL--------EGGPRDPGPSAPPPRSGPRGQLASPD 104
P PGAA G + G GL +G P PG P + GPRG
Sbjct: 709 AAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIG 768
Query: 105 APG----PGPRSEAPLPELDPLFSWTEEPEECGPASCPESAPF-------RLQGSSSSHR 153
PG PG + E P L + P E G P A F G
Sbjct: 769 PPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERG 828
Query: 154 ARGEVDVFSP--FPAPTAGELALEQGPGSPPQPSDLSQTHPLPSEPVGSQEDGPR 206
A GE P P G GP PP P + P P + G R
Sbjct: 829 APGEKGEGGPPGVAGPPGG-----SGPAGPPGPQGVKGERGSPGGPGAAGFPGAR 878
Score = 56.2 bits (134), Expect = 1e-07
Identities = 59/192 (30%), Positives = 71/192 (36%), Gaps = 20/192 (10%)
Query: 6 PASPPG-SEPPGPDPEPGGPDGPGAAQLAPGPAEL-RLGAPVGGPDPQSPGLDEPAPGAA 63
P PPG + PG E G P PG A P E G P P +PG + G
Sbjct: 766 PIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKG 825
Query: 64 ADG--GARWSAGPAPGLEGGPRDPGPSAPPPRSGPRGQLASPDAPG----PGPRSEAPLP 117
G G + GP PG+ G P GP+ PP G +G+ SP PG PG R P
Sbjct: 826 ERGAPGEKGEGGP-PGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPP 884
Query: 118 ELDPLFSWTEEPEECGPASCP-ESAPFRLQGSSSSHRARGEVDVFSP-FPAPTAGELALE 175
P GP+ P + P G + + A G V P A GE
Sbjct: 885 ------GSNGNPGPPGPSGSPGKDGP---PGPAGNTGAPGSPGVSGPKGDAGQPGEKGSP 935
Query: 176 QGPGSPPQPSDL 187
G P P L
Sbjct: 936 GAQGPPGAPGPL 947
Score = 55.5 bits (132), Expect = 2e-07
Identities = 48/149 (32%), Positives = 54/149 (36%), Gaps = 49/149 (32%)
Query: 6 PASPPGSEPPGPDPEPG-----GPDGPGAAQLAPGPAELRLGAPVGGPDPQSPGLDEP-- 58
P +P PPGP G G GP APGPA R G P PQ P D+
Sbjct: 1043 PGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSR-----GAPGPQGPRGDKGET 1097
Query: 59 ----------------------APGAAADGGARWSAGPA-----------PGLEGGPRDP 85
+PG A GA S GPA PG +G P
Sbjct: 1098 GERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHP 1157
Query: 86 GPSAPPPRSGPRGQLASPDAPG----PGP 110
GP PP G RG+ S +PG PGP
Sbjct: 1158 GPIGPPGPRGNRGERGSEGSPGHPGQPGP 1186
Score = 54.3 bits (129), Expect = 4e-07
Identities = 68/224 (30%), Positives = 78/224 (34%), Gaps = 35/224 (15%)
Query: 6 PASPPGSEPPGPDPEPG--GPDGPGAAQLAPG----PAEL-RLGAPVGGPDPQSPGLDEP 58
P G+ PPGP+ G GP GP A PG P E LG+P D PG
Sbjct: 692 PGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPG-GPG 750
Query: 59 APGAAADGGARWSAGP--APGLEGGPRDPGPSAPP-------PRSGPRGQLASPDAPGPG 109
A G G R GP PG G P D G P PR P G+ PGP
Sbjct: 751 ADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSP-GERGETGPPGPA 809
Query: 110 PRSEAPLPELDPLFSWTEEPEECGPASCPESAPFRLQGSSSSHRARGEVDVFSPFPAPTA 169
AP +P + E P E P + G G P P
Sbjct: 810 GFPGAPGQNGEP----GGKGERGAPGEKGEGGPPGVAGPPGGSGPAG-----PPGPQGVK 860
Query: 170 GELALEQGPGSPPQPSDL-------SQTHPLPSEPVGSQ-EDGP 205
GE GPG+ P S +P P P GS +DGP
Sbjct: 861 GERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGP 904
Score = 53.5 bits (127), Expect = 7e-07
Identities = 67/228 (29%), Positives = 80/228 (35%), Gaps = 62/228 (27%)
Query: 4 APPASPPG-------SEPPGPDPEPGGPDGPGAAQLAPGPAELRLGAPVGG--------- 47
A P+ PPG S P G D E G P PG L PGP ++ A + G
Sbjct: 209 AGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGL-PGPPGIKGPAGIPGFPGMKGHRG 267
Query: 48 --------PDPQSPGLDEPAPGAAADGGARWSAGP--APGLEGGPRDPGPSAPPPRSGPR 97
+ +PGL + G + GA GP APG G P PG + G R
Sbjct: 268 FDGRNGEKGETGAPGL-KGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGAR 326
Query: 98 GQLASPDAPGPGPRSEAPLPELDPLFSWTEEPEECGPASCPESAPFRLQGSSSSHRARGE 157
G P PGP + P E GPA P GS+ + RGE
Sbjct: 327 GSDGQPGPPGPPGTAGFP--------GSPGAKGEVGPAGSP--------GSNGAPGQRGE 370
Query: 158 VDVFSPFPAPTAGELALEQGPGSPPQPSDLSQTHPLPSEPVGSQEDGP 205
P P AG QGP PP + P G E GP
Sbjct: 371 -----PGPQGHAG----AQGPPGPP---------GINGSPGGKGEMGP 400
Score = 52.8 bits (125), Expect = 1e-06
Identities = 67/220 (30%), Positives = 86/220 (39%), Gaps = 38/220 (17%)
Query: 6 PASPPGSEPPGPDPEPGGPDGPGAAQLAPGPAELRLGAPVGGPDPQSPGLDEPAPGAAAD 65
PA PPG PPGP G P PG+ P E P G P P PG P+ A D
Sbjct: 175 PAGPPG--PPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGP--PGAIGPSGPAGKD 230
Query: 66 GGARWSAGPAP-GLEGGPRDPGPSAPP------------PRSGPRGQLASPDAPG----P 108
G + P GL G P GP+ P R+G +G+ +P G P
Sbjct: 231 GESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLP 290
Query: 109 GPRSEAPLPELDPLFSWTEEPEECGPASCPESAPFRLQGSSSSHRARGEVDVFSP----- 163
G + AP P + P P E G P +A R G+ + + G+ P
Sbjct: 291 G-ENGAPGP-MGP----RGAPGERGRPGLPGAAGAR--GNDGARGSDGQPGPPGPPGTAG 342
Query: 164 FP-APTA-GELALEQGPGSPPQPSDLSQTHPLPSEPVGSQ 201
FP +P A GE+ PGS P + P P G+Q
Sbjct: 343 FPGSPGAKGEVGPAGSPGSNGAPGQRGE--PGPQGHAGAQ 380
Score = 52.4 bits (124), Expect = 2e-06
Identities = 60/214 (28%), Positives = 71/214 (33%), Gaps = 19/214 (8%)
Query: 6 PASPPGSEPPGPDPEPGGPDG---PGAAQLAPGPAELRLGAPVGGPDPQSPGLDEPAPGA 62
P P G D PG P PGAA P P G P + P + APG
Sbjct: 455 PGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGP 514
Query: 63 AADGGARWSAGP-----APGLEGGPRDPGPSAPPPRSGP---RGQLASPDAPGP-GPRSE 113
A GA G PG+ G P PG + GP +G+ P PGP GPR +
Sbjct: 515 AGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQ 574
Query: 114 APLPELDPLFSWTEEPEECGPASCPESAPFRLQGSSSSHRARGEVDVFSPFPAPTA-GEL 172
+ P + G P G GE P P PT G
Sbjct: 575 PGVMGFPGPKGNDGAPGKNGERGGPGG-----PGPQGPPGKNGETGPQGP-PGPTGPGGD 628
Query: 173 ALEQGPGSPPQPSDLSQTHPLPSEPVGSQEDGPR 206
+ GP P L T P E E GP+
Sbjct: 629 KGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPK 662
Score = 51.6 bits (122), Expect = 3e-06
Identities = 43/135 (31%), Positives = 50/135 (37%), Gaps = 28/135 (20%)
Query: 3 SAPPASPPGSEPPGPDPEPGGPDGPG-----------AAQLAPGPAELRLGAPVGGPDPQ 51
+AP P G P GP +PG P PG + +PGP + P G P
Sbjct: 93 TAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTG-PQNY 151
Query: 52 SPGLDE-PAPGAAADGGARWSAGPA--------------PGLEGGPRDPGPSAPPPRSGP 96
SP D A GG GPA PG G P GP P ++GP
Sbjct: 152 SPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGP 211
Query: 97 RGQLASPDAPGP-GP 110
G P A GP GP
Sbjct: 212 SGPPGPPGAIGPSGP 226
Score = 51.2 bits (121), Expect = 3e-06
Identities = 31/100 (31%), Positives = 37/100 (37%), Gaps = 1/100 (1%)
Query: 16 GPDPEPGGPDGPGAAQLAPGPAELRLGAPVGGPDPQSPGLDEPAPGAAADGGARWSAGPA 75
G D +PG P PG A P P G P PG GA+ GP
Sbjct: 327 GSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGP- 385
Query: 76 PGLEGGPRDPGPSAPPPRSGPRGQLASPDAPGPGPRSEAP 115
PG+ G P G P G G + + PGP + AP
Sbjct: 386 PGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAP 425
Score = 51.2 bits (121), Expect = 3e-06
Identities = 82/277 (29%), Positives = 93/277 (33%), Gaps = 68/277 (24%)
Query: 2 ASAPPA------SPPGSEPPGPDPEPG--------GPDGPGAAQLAPGPAELRLGA---- 43
A PP SP G GP PG GP GP A APG LR GA
Sbjct: 379 AQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPG---LRGGAGEPG 435
Query: 44 ---PVGGPDPQS-------PGLDEPAPGAAADGGARWSAGP--------APGLEGGPRDP 85
G P P+ PG+ PGA + G S G A G G P
Sbjct: 436 KNGAKGEPGPRGERGEAGIPGV----PGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFR 491
Query: 86 GPSAPPPRSGPRGQLASPDAPGP-GPRSEAPLPELDPLFSWT----EEPEECGPASCPES 140
GP+ P G +G APGP GPR A P D + GP S +
Sbjct: 492 GPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKP 551
Query: 141 APFRLQGSS------SSHRARGEVDVFSPFPAPTA--------GELALEQGPGSPPQPSD 186
P QG S RG+ V FP P GE GPG P
Sbjct: 552 GPPGSQGESGRPGPPGPSGPRGQPGVMG-FPGPKGNDGAPGKNGERGGPGGPGPQGPPGK 610
Query: 187 LSQTHPL----PSEPVGSQED-GPRLRAVFDALDGDG 218
+T P P+ P G + D GP L G G
Sbjct: 611 NGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTG 647
Score = 47.8 bits (112), Expect = 4e-05
Identities = 41/137 (29%), Positives = 51/137 (37%), Gaps = 28/137 (20%)
Query: 5 PPASPPGSEPPGPDPEPGGPDGPGAAQLAP----GPA---------ELRLGAPVGG---- 47
PP P + PG +PG P PG + GP +++ G VGG
Sbjct: 113 PPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGY 172
Query: 48 PDPQSPGLDEPAPGAAADGGARWSAGPAPGLEGGPRDP------GPSAPPPRSGPRGQLA 101
P P P PG + G+ S PG +G P +P GP PP GP G
Sbjct: 173 PGPAGPPGPPGPPGTSGHPGSPGS----PGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAG 228
Query: 102 SPDAPG-PGPRSEAPLP 117
G PG E LP
Sbjct: 229 KDGESGRPGRPGERGLP 245
Score = 41.2 bits (95), Expect = 0.004
Identities = 36/126 (28%), Positives = 43/126 (34%), Gaps = 14/126 (11%)
Query: 82 PRDP-GPSAPPPRSGPRGQLASPDAPG-PGPRSEAPLPELDPLFSWTEEPEECGPASCPE 139
P+ P P+ PP GP+G P PG PG + +P P GP E
Sbjct: 89 PQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIP------GQPGSPGSPGPPGICE 142
Query: 140 SAPFRLQGSSSSHRARGEVDVFSPFPAPTAGELALEQGPGSPPQPSDLSQTHPLPSEPVG 199
S P Q S + D + G LA GP PP P T P P
Sbjct: 143 SCPTGPQNYSPQY------DSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGS 196
Query: 200 SQEDGP 205
GP
Sbjct: 197 PGYQGP 202
Score = 34.7 bits (78), Expect = 0.34
Identities = 39/123 (31%), Positives = 44/123 (35%), Gaps = 28/123 (22%)
Query: 1 MASAPPASPPGSEPPGPDPEPGGPDGPGAAQLAPGPAELRLGAPVGGPDPQSPGLDEPAP 60
+ S PA P G P G P GP G PGP GP P
Sbjct: 1130 IGSPGPAGPRG--PVG----PSGPPGKDGTSGHPGPI---------GP-----------P 1163
Query: 61 GAAADGGARWSAGPAPGLEGGPRDPG-PSAPPPRSGPRGQLASPDAPGPGPRSEAPLPEL 119
G + G R S G +PG G P PG P AP P G G A G AP
Sbjct: 1164 GPRGNRGERGSEG-SPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEKAGGFAPYYGD 1222
Query: 120 DPL 122
+P+
Sbjct: 1223 EPM 1225
Score = 30.0 bits (66), Expect = 8.3
Identities = 27/86 (31%), Positives = 35/86 (40%), Gaps = 10/86 (11%)
Query: 6 PASPPGSEP----PGP--DPEPGGPDGPGAAQLAPG-PAELRLGAPVGGPDPQSPGLDEP 58
P+ PPG + PGP P P G G ++ +PG P + P G P P G+
Sbjct: 1144 PSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGV--- 1200
Query: 59 APGAAADGGARWSAGPAPGLEGGPRD 84
A A G + G AP P D
Sbjct: 1201 GAAAIAGIGGEKAGGFAPYYGDEPMD 1226
>gi|4502443 dystonin isoform 1e precursor [Homo sapiens]
Length = 2649
Score = 64.3 bits (155), Expect = 4e-10
Identities = 67/303 (22%), Positives = 134/303 (44%), Gaps = 32/303 (10%)
Query: 425 KRLSSKKVARYLHQS--GALTMEALEDPSPELMEGPEEDIADKVVFLERRVLELEKDTAA 482
KRL +++ R S GA + + L+ ++E + + K+ LER V EL+K +
Sbjct: 1100 KRLEEEEIKRCKETSEHGAYS-DLLQRQKATVLENSK--LTGKISELERMVAELKKQKSR 1156
Query: 483 TGEQHSRLRQE---------------NLQLVHRANALEEQLKEQE--LRACEMVLEETRR 525
E+ ++R+ +LQ + + ++ +E E +R E E R
Sbjct: 1157 VEEELPKVREAAENELRKQQRNVEDISLQKIRAESEAKQYRRELETIVREKEAAERELER 1216
Query: 526 QKELLCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKA---NIERLEEEKQKLLDE 582
++L + E +++ ENL QL+E R+ LK ++ LE++K KL++E
Sbjct: 1217 VRQLTIEAEAKRAAVEENLLNFRNQLEENTFTRRTLEDHLKRKDLSLNDLEQQKNKLMEE 1276
Query: 583 IESLTLRLSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLE---- 638
+ E + ++M L+ ++ ++ + Q++ + R+++ +Q E
Sbjct: 1277 LRRKRDNEEELLKLIKQMEKDLAFQKQVAEKQLKEKQKIELEARRKITEIQYTCRENALP 1336
Query: 639 ---AEQRRGRSSSMGLQEYHSRARESELEQEVRRLKQDNRNLKEQNEELNGQIITLSIQG 695
Q + GLQ+ H + + EL+Q+V L NR ++ EL ++ L ++
Sbjct: 1337 VCPITQATSCRAVTGLQQEHDKQKAEELKQQVDELTAANRKAEQDMRELTYELNALQLEK 1396
Query: 696 AKS 698
S
Sbjct: 1397 TSS 1399
Score = 55.8 bits (133), Expect = 1e-07
Identities = 69/328 (21%), Positives = 143/328 (43%), Gaps = 36/328 (10%)
Query: 430 KKVARYLHQSGALTMEALEDPSP------------ELMEGPEEDIADKVVFLERRVLELE 477
+++ R L+Q+ EA+++ S E + + + +V + R E
Sbjct: 1439 RELGRQLNQTTGKAEEAMQEASDLKKIKRNYQLELESLNHEKGKLQREVDRITRAHAVAE 1498
Query: 478 KDTAATGEQ-HSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELLCKMER- 535
K+ Q HS ++ L+ + + LKEQ ++ E +L+ + +KE K++R
Sbjct: 1499 KNIQHLNSQIHSFRDEKELERLQICQRKSDHLKEQFEKSHEQLLQNIKAEKENNDKIQRL 1558
Query: 536 ----EKSIEI-ENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLRL 590
EKS E E L+ ++++L +N+E + ++A E + EKQ + E+L ++
Sbjct: 1559 NEELEKSNECAEMLKQKVEELTRQNNETKLMMQRIQAESENIVLEKQTIQQRCEALKIQA 1618
Query: 591 SEEQENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQR-------- 642
++ R + L + Q + + L EDL K + K + +Q+
Sbjct: 1619 DGFKDQLRSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIIIQNTK 1678
Query: 643 ---RGRSSSMGLQEYHSRARESELEQEVRRLKQDNRNLKEQNEELNGQIITLSIQGAKSL 699
R ++ + + R E +++ + ++++ N LK+ +EL+ + I + K +
Sbjct: 1679 KEVRNLNAELNASKEEKRRGEQKVQLQQAQVQELNNRLKKVQDELHLKTIEEQMTHRKMV 1738
Query: 700 F----STAFSESLAAEISSVSRDELMEA 723
S F +S AE ++LME+
Sbjct: 1739 LFQEESGKFKQS--AEEFRKKMEKLMES 1764
Score = 53.5 bits (127), Expect = 7e-07
Identities = 59/249 (23%), Positives = 109/249 (43%), Gaps = 34/249 (13%)
Query: 506 EQLKEQELRACEMVLEETRRQKELLCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCL 565
++L+E+E++ C+ ET ++R+K+ +EN +L + SEL L
Sbjct: 1100 KRLEEEEIKRCK----ETSEHGAYSDLLQRQKATVLEN-----SKLTGKISELERMVAEL 1150
Query: 566 KANIERLEEEKQKLLDEIESLTLRLSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDL 625
K R+EEE K+ + E+ + E+ R E Q++R+ E E
Sbjct: 1151 KKQKSRVEEELPKVREAAENELRKQQRNVEDISLQKIRAESEAKQYRRELETIVREKEAA 1210
Query: 626 RKQLEHLQLLKLEAEQRRGRSSSMGLQ---------------EYHSRARE---SELEQEV 667
++LE ++ L +EAE +R L E H + ++ ++LEQ+
Sbjct: 1211 ERELERVRQLTIEAEAKRAAVEENLLNFRNQLEENTFTRRTLEDHLKRKDLSLNDLEQQK 1270
Query: 668 RRLKQDNRNLKEQNEELNGQIITLSIQGAKSLFSTAFSESLAAEISSVSRDELMEAIQKQ 727
+L ++ R ++ EEL + L Q K L AF + +A + + +EA +K
Sbjct: 1271 NKLMEELRRKRDNEEEL----LKLIKQMEKDL---AFQKQVAEKQLKEKQKIELEARRKI 1323
Query: 728 EEINFRLQD 736
EI + ++
Sbjct: 1324 TEIQYTCRE 1332
Score = 43.5 bits (101), Expect = 7e-04
Identities = 38/177 (21%), Positives = 81/177 (45%), Gaps = 17/177 (9%)
Query: 474 LELEKDTAATGEQHSRLRQENLQ-LVHRANALEEQLK----EQELRACEMVL-------- 520
L K+ GEQ +L+Q +Q L +R ++++L E+++ +MVL
Sbjct: 1688 LNASKEEKRRGEQKVQLQQAQVQELNNRLKKVQDELHLKTIEEQMTHRKMVLFQEESGKF 1747
Query: 521 ----EETRRQKELLCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKANIERLEEEK 576
EE R++ E L + + +I ++ L +ENS + + NI+ LE +
Sbjct: 1748 KQSAEEFRKKMEKLMESKVITENDISGIRLDFVSLQQENSRAQENAKLCETNIKELERQL 1807
Query: 577 QKLLDEIESLTLRLSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQ 633
Q+ ++++ + + +++ D L ++ + + K+ + I++ QL LQ
Sbjct: 1808 QQYREQMQQGQHMEANHYQKCQKLEDELIAQKREVENLKQKMDQQIKEHEHQLVLLQ 1864
Score = 42.0 bits (97), Expect = 0.002
Identities = 59/301 (19%), Positives = 126/301 (41%), Gaps = 34/301 (11%)
Query: 459 EEDIADKVVFLERRV-LELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQELRACE 517
E++ A++ + R++ +E E AA E R + + LE+ LK ++L
Sbjct: 1206 EKEAAERELERVRQLTIEAEAKRAAVEENLLNFRNQLEENTFTRRTLEDHLKRKDLS--- 1262
Query: 518 MVLEETRRQKELLCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQ 577
L + +QK L + R K E L ++Q++++ + + +++E E +
Sbjct: 1263 --LNDLEQQKNKLMEELRRKRDNEEELLKLIKQMEKDLAFQKQVAEKQLKEKQKIELEAR 1320
Query: 578 KLLDEIE-----------------SLTLRLSEEQENKRRMGDRLSHERHQFQRDKEATQE 620
+ + EI+ S +QE+ ++ + L + + ++
Sbjct: 1321 RKITEIQYTCRENALPVCPITQATSCRAVTGLQQEHDKQKAEELKQQVDELTAANRKAEQ 1380
Query: 621 LIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARESELEQEVRRLKQDNRNLKEQ 680
+ +L +L LQL K +E+ + R L E ++ R +LE E R Q + +Q
Sbjct: 1381 DMRELTYELNALQLEKTSSEE-KARLLKDKLDETNNTLRCLKLELE--RKDQAEKGYSQQ 1437
Query: 681 NEELNGQIITLSIQGAKSLFSTAFSESLAAEISSVSRDELMEAIQKQEEINFRLQDYIDR 740
EL Q+ + + +++ A+++ + R+ +E ++ +LQ +DR
Sbjct: 1438 LRELGRQLNQTTGKAEEAM-------QEASDLKKIKRNYQLE-LESLNHEKGKLQREVDR 1489
Query: 741 I 741
I
Sbjct: 1490 I 1490
Score = 38.1 bits (87), Expect = 0.030
Identities = 53/250 (21%), Positives = 105/250 (42%), Gaps = 36/250 (14%)
Query: 459 EEDIADKVVFLERRVLELEKDTAATGEQHSRLRQENLQL------VHRANALEEQLKEQE 512
E+D K+ LE +L K E + Q+N+ + V NA KE++
Sbjct: 1639 EQDFQRKIKCLEE---DLAKSQNLVSEFKQKCDQQNIIIQNTKKEVRNLNAELNASKEEK 1695
Query: 513 LRACEMVLEETRRQKEL---LCKMERE---KSIEIENLQTRLQQLDEENSELRSCTPCLK 566
R + V + + +EL L K++ E K+IE + ++ EE+ + + +
Sbjct: 1696 RRGEQKVQLQQAQVQELNNRLKKVQDELHLKTIEEQMTHRKMVLFQEESGKFKQSAEEFR 1755
Query: 567 ANIERLEEEKQKLLDEIESLTLR-LSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDL 625
+E+L E K ++I + L +S +QEN R Q + + + I++L
Sbjct: 1756 KKMEKLMESKVITENDISGIRLDFVSLQQENSRA------------QENAKLCETNIKEL 1803
Query: 626 RKQLEHLQLLKLEAEQRRGRSSSMGLQEYHS-RARESELEQEVRRLKQDNRNLKEQNEEL 684
+QL+ + ++ + M Y + E EL + R ++ + + +Q +E
Sbjct: 1804 ERQLQ-------QYREQMQQGQHMEANHYQKCQKLEDELIAQKREVENLKQKMDQQIKEH 1856
Query: 685 NGQIITLSIQ 694
Q++ L +
Sbjct: 1857 EHQLVLLQCE 1866
Score = 32.3 bits (72), Expect = 1.7
Identities = 43/202 (21%), Positives = 75/202 (37%), Gaps = 40/202 (19%)
Query: 541 IENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLRLSEEQENKRRM 600
+ NLQ+R + E++ E + + ++I +LE+E + L E++ +
Sbjct: 683 LSNLQSRFEDFLEDSQESQVFSG---SDITQLEKEVNVCKQYYQELLKSAEREEQEESVY 739
Query: 601 GDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARE 660
+S R+ R + LI +R LE L E R E
Sbjct: 740 NLYISEVRNIRLRLENCEDRLIRQIRTPLERDDL-----------------HESVFRITE 782
Query: 661 SE-LEQEVRRLKQDNRNLKEQNEELNGQIITLSIQGAKSLFSTAFSESLAAEISSVSRDE 719
E L++E+ RLK D + + EE FS++ A+ R E
Sbjct: 783 QEKLKKELERLKDDLGTITNKCEEF-------------------FSQAAASSSVPTLRSE 823
Query: 720 LMEAIQKQEEINFRLQDYIDRI 741
L +Q ++ YID++
Sbjct: 824 LNVVLQNMNQVYSMSSTYIDKL 845
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 64.3 bits (155), Expect = 4e-10
Identities = 79/308 (25%), Positives = 133/308 (43%), Gaps = 51/308 (16%)
Query: 472 RVLELEKDTAATGEQHSRLRQEN---LQLVHRANALEEQLKEQELRACEMVLEETRRQKE 528
+V EL++ A Q RL+ E+ +L+ L QL + A + LEE RRQ E
Sbjct: 1311 KVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQS-LEELRRQLE 1369
Query: 529 LL-----------------CKMEREKSIEIENLQTRLQQ-LDEENSELRSCTPCLKAN-- 568
C + RE+ E Q LQ+ L + N+E+ +A+
Sbjct: 1370 EESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAI 1429
Query: 569 --IERLEEEKQKL-----------------LDEIESLTLRLSEEQENKRRMGDRLSHERH 609
E LEE K+KL +E LRL E E+ +R +
Sbjct: 1430 QRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAA 1489
Query: 610 QFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARESELEQEVRR 669
+ + + +E+ R+Q E +Q +LEA QR R +G + + R E + +
Sbjct: 1490 ALDKKQRHLERALEERRRQEEEMQ-RELEAAQRESR--GLGTELFRLRHGHEEALEALET 1546
Query: 670 LKQDNRNLKEQNEELNGQIITLSIQGAKSLFSTAFSESLAAEISSV--SRDELMEAIQKQ 727
LK++N+NL+E+ +L Q ++LS + + L T ++L E S + + +E A++ +
Sbjct: 1547 LKRENKNLQEEISDLTDQ-VSLSGKSIQELEKT--KKALEGEKSEIQAALEEAEGALELE 1603
Query: 728 EEINFRLQ 735
E R+Q
Sbjct: 1604 ETKTLRIQ 1611
Score = 53.9 bits (128), Expect = 5e-07
Identities = 64/247 (25%), Positives = 104/247 (42%), Gaps = 32/247 (12%)
Query: 465 KVVFLERRVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQL---------------- 508
K+ L+ R ELE++ A +R+ ++ + L E+L
Sbjct: 1156 KIKELQARAEELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRK 1215
Query: 509 KEQELRACEMVLEETRRQKELLCKMEREKSIE--------IENLQTRLQQLDEENSELRS 560
+E EL LEE + E R K E +++LQ Q+L++E SELR
Sbjct: 1216 REAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRM 1275
Query: 561 CTPCLKANIERLEEEKQKLLDEIESLTLRLSEE----QENKRRMGDRLSHERHQFQRDKE 616
L AN+E L K + +LSE +E +R++ D S +R + Q +
Sbjct: 1276 EVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLAD-ASTQRGRLQTESG 1334
Query: 617 ATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARESELEQEVRRLKQDNRN 676
L+E+ K+ QL + +A + E S+A+ S L V+ L+ D
Sbjct: 1335 ELSRLLEE--KECLISQLSRGKALAAQSLEELRRQLEEESKAK-SALAHAVQALRHDCDL 1391
Query: 677 LKEQNEE 683
L+EQ+EE
Sbjct: 1392 LREQHEE 1398
Score = 53.5 bits (127), Expect = 7e-07
Identities = 74/299 (24%), Positives = 124/299 (41%), Gaps = 47/299 (15%)
Query: 474 LELEKDTAATGEQHSRLR-QENLQLVHRANALEEQLKEQE-----LRACEMVLEE--TRR 525
L+ E+D A E+ L + +QL + L E+L+++E L A LE+ T
Sbjct: 940 LQAEQDNLADAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTEL 999
Query: 526 QKEL------LCKMEREKSI---EIENLQTRLQQLDEENSELRSCTPCLKANIERLEEEK 576
+K++ L K E+EK +++NL + LDE + L L+ ++ +
Sbjct: 1000 KKDIDDLKLTLAKAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDL 1059
Query: 577 QKLLDEIESLT------------LRLSEEQENKRRMGDRLSHERHQFQRDKEATQELIED 624
Q D + +LT L S EQE K RM + + + + D + TQE + D
Sbjct: 1060 QAEEDRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERA--KRKLEGDLKLTQESVAD 1117
Query: 625 -----------LRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARESELEQEVRRLKQD 673
L+K+ L L L E + + M + +AR ELE+E+ +
Sbjct: 1118 AAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAA 1177
Query: 674 NRNLKEQNEELNGQIITLSIQ----GAKSLFSTAFSESLAAEISSVSRDELMEAIQKQE 728
+++Q E ++ LS + G S AE+ + R EL EA + E
Sbjct: 1178 RARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRR-ELEEAALRHE 1235
Score = 53.5 bits (127), Expect = 7e-07
Identities = 65/277 (23%), Positives = 116/277 (41%), Gaps = 18/277 (6%)
Query: 460 EDIADKVVFLERRVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLK---------E 510
E++ + L R+ E E+ A + S L + L+L + + +L+ +
Sbjct: 1433 EELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALD 1492
Query: 511 QELRACEMVLEETRRQKELLCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKANIE 570
++ R E LEE RRQ+E + + E L T L +L + E LK +
Sbjct: 1493 KKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENK 1552
Query: 571 RLEEEKQKLLDEIESLTLRLSEEQENKRRMGDRLSHERHQFQRDKEATQ-ELIEDLRKQL 629
L+EE L D++ + E ++ K+ + S + + + A + E + LR QL
Sbjct: 1553 NLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQL 1612
Query: 630 EHLQLLKLEAEQRRGRSSS--MGLQEYHSRARES---ELEQEVRRLKQDNRNLKEQNEEL 684
E L +K E +++ L+ H RA ES L+ E R + R K+ +L
Sbjct: 1613 E-LSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDL 1671
Query: 685 NGQIITLSIQGAKSLFSTAFSESLAAEI--SSVSRDE 719
N + L ++ + A + + A++ RDE
Sbjct: 1672 NDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDE 1708
Score = 39.7 bits (91), Expect = 0.010
Identities = 58/280 (20%), Positives = 110/280 (39%), Gaps = 41/280 (14%)
Query: 453 ELMEGPEEDIADKVVFLERRVLELEKDTA---ATGEQHSRLRQENLQLVHRANALEEQLK 509
+L+ E+ A+ L+R + + + A + E + R E L+ + AL Q
Sbjct: 1390 DLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEA 1449
Query: 510 EQELRACEMVLEETRRQKELLCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKANI 569
E+ + A + K L + ++E+E + LD++ + ++
Sbjct: 1450 EEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKK-----------QRHL 1498
Query: 570 ERLEEEKQKLLDEIESLTLRLSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQL 629
ER EE+++ +E++ L Q R +G L RH + + L
Sbjct: 1499 ERALEERRRQEEEMQR---ELEAAQRESRGLGTELFRLRHGHE--------------EAL 1541
Query: 630 EHLQLLKLEAEQRRGRSSSMGLQEYHSRARESELEQEVRRLKQDNRNLKEQNEELNGQII 689
E L+ LK E + + S + Q S ELE+ + L+ + ++ EE G
Sbjct: 1542 EALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEG--- 1598
Query: 690 TLSIQGAKSLFSTAFSESLAAEISSVSRDELMEAIQKQEE 729
L ++ K+L + E+S V + + +K EE
Sbjct: 1599 ALELEETKTL-------RIQLELSQVKAEVDRKLAEKDEE 1631
Score = 35.8 bits (81), Expect = 0.15
Identities = 36/169 (21%), Positives = 70/169 (41%), Gaps = 29/169 (17%)
Query: 545 QTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLRLSEEQEN-------- 596
+ L L E LR +A + LEE + E L L+L EQ+N
Sbjct: 895 EEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEERC 954
Query: 597 -------------KRRMGDRLSHERHQFQRDKEATQELIED----LRKQLEHLQLLKLEA 639
+ + +RL E + D A + +ED L+K ++ L+L +A
Sbjct: 955 HLLIKSKVQLEGKVKELSERLEDE-EEVNADLAARRRKLEDECTELKKDIDDLKLTLAKA 1013
Query: 640 EQRRGRSSSMGLQEYHSRARESELEQEVRRLKQDNRNLKEQNEELNGQI 688
E+ + + + + + + L++ V RL ++ + L+E +++ G +
Sbjct: 1014 EKEKQATEN---KVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDL 1059
Score = 35.4 bits (80), Expect = 0.20
Identities = 57/272 (20%), Positives = 111/272 (40%), Gaps = 42/272 (15%)
Query: 490 LRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELLCKMEREKSIEIENLQTRLQ 549
L LQL H E L ++ E+ R +E ++ E + + L+ R
Sbjct: 1671 LNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQ--RLAAELHEQAQALERRAS 1728
Query: 550 QLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLRLSEE----QENKRRMGD--R 603
L E ELR+ L+ +Q+LL+ E L L S+ + K+ D +
Sbjct: 1729 LLAAELEELRA---ALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQ 1785
Query: 604 LSHERHQFQRDKEATQE-----------LIEDLRKQLE---HLQLLKLEAEQRRGRSSSM 649
LS E + +++ +E + E+L+K+ + HL+ +K EQ
Sbjct: 1786 LSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQT------- 1838
Query: 650 GLQEYHSRARESELEQEVRRLKQDNRNLKEQNEELNGQIITLSIQGAKSLFSTAFSESLA 709
++E +R E+E + +R K+ + L+ + EL ++ + A++L E
Sbjct: 1839 -VRELQARLEEAE-QAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRV 1896
Query: 710 AEISSVSRDELMEAIQKQEEINFRLQDYIDRI 741
E++ + ++ R+QD +D++
Sbjct: 1897 KELAYQAEEDRKNLA--------RMQDLVDKL 1920
Score = 31.6 bits (70), Expect = 2.8
Identities = 36/208 (17%), Positives = 86/208 (41%), Gaps = 18/208 (8%)
Query: 455 MEGPEEDIADKVVFLERRVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQELR 514
+ G E+ A + E + + D A E+ + + + L LE+ ++E + R
Sbjct: 1786 LSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQAR 1845
Query: 515 ACEMVLEETRRQKELLCKMEREKSIEIENLQTRLQQLDEE-NSELRSCTPCLKANIERLE 573
E R K+ +++ L+ ++++L+ E ++E + LK + + E
Sbjct: 1846 LEEAEQAALRGGKK-----------QVQKLEAKVRELEAELDAEQKKHAEALK-GVRKHE 1893
Query: 574 EEKQKLLDEIESLTLRLSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQ 633
++L + E L+ Q+ ++ ++ + QF+ ++ + RK L
Sbjct: 1894 RRVKELAYQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELD 1953
Query: 634 LLKLEAEQRRGRSSSMGLQEYHSRARES 661
+AE+R + + + +R R++
Sbjct: 1954 ----DAEERADMAETQA-NKLRARTRDA 1976
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 63.9 bits (154), Expect = 5e-10
Identities = 49/129 (37%), Positives = 53/129 (41%), Gaps = 16/129 (12%)
Query: 5 PPASPPGSE-PPGPDPE----PGGPDGPGAAQLAPGPAELRLGAPVGGPD--PQSPGLDE 57
PP PPG PPGP P P GP P P L G P G P P PG
Sbjct: 239 PPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPP 298
Query: 58 PAPGAAADGGARWSAGPAPGLEGGPRDPGPSAPPPRS--GPRGQLASPD-APGPGPRSEA 114
P PG GP P +G P PGP P P GP LA P PGP P +
Sbjct: 299 PVPGYGPP------PGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPP 352
Query: 115 PLPELDPLF 123
P P ++P F
Sbjct: 353 PAPHVNPAF 361
Score = 55.1 bits (131), Expect = 2e-07
Identities = 56/190 (29%), Positives = 61/190 (32%), Gaps = 29/190 (15%)
Query: 5 PPASPPGSEPPGPDPEPGGPDGPGAAQLAPGPAELRLGAPVGGPDPQSPGLDEPAPGAAA 64
P A P G PGP PGGP P A P L P G P P PG P P A
Sbjct: 208 PGAVPGGDRFPGP-AGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGP 266
Query: 65 DG------------GARWSAGPAPGLEGGPRDPGPSAPPPRSGPRGQLASPDAPGPGPRS 112
G + P L GP P P PP P Q P PGP P
Sbjct: 267 PNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFP-- 324
Query: 113 EAPLPELDPLFSWTEEPEECGPASCPESAPFRLQGSSSSHRARGEVDVFSPFPAPTAGEL 172
P L P + P GP P AP + + FP PT +
Sbjct: 325 PRPPGPLGPPLTLAPPPHLPGP---PPGAPPPAPHVNPAF-----------FPPPTNSGM 370
Query: 173 ALEQGPGSPP 182
G PP
Sbjct: 371 PTSDSRGPPP 380
Score = 43.5 bits (101), Expect = 7e-04
Identities = 43/146 (29%), Positives = 48/146 (32%), Gaps = 23/146 (15%)
Query: 60 PGAAADGGARWSAGPAPGLEGGPRDPGPSAPPPRSGPRGQLASPDAPGPGPRSEAPLPEL 119
PGA GG R+ P P GGP P P+ P P G P PGP P + P L
Sbjct: 208 PGAVP-GGDRF---PGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPL 263
Query: 120 DPLFSWTEEPEECGPASCPESAPFRLQGSSSSHRARGEVDVFSPFPAPTAGELALEQGPG 179
P G P P G G + P P P G G
Sbjct: 264 -------AGPPNRGDRPPP---PVLFPGQPFGQPPLGPLPPGPPPPVP---------GYG 304
Query: 180 SPPQPSDLSQTHPLPSEPVGSQEDGP 205
PP P Q P P P + GP
Sbjct: 305 PPPGPPPPQQGPPPPPGPFPPRPPGP 330
>gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo
sapiens]
Length = 479
Score = 63.9 bits (154), Expect = 5e-10
Identities = 76/278 (27%), Positives = 119/278 (42%), Gaps = 33/278 (11%)
Query: 430 KKVARYLHQSGALTMEALEDPSPELMEGPEEDIADKVVFLERRVLELEKDTAATGEQHSR 489
+K+ R L + T E L +PE GP KV L+ L K+ + G Q
Sbjct: 131 QKLGRSLFKLKNQTAEPL---APEPPAGPS-----KVEQLQDETNHLRKELESVGRQLQA 182
Query: 490 LRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELLCKMEREKSIEIENLQTRLQ 549
+ N L EE+L+EQE R E E Q+E LC+ E + E L+ + +
Sbjct: 183 EVENNQMLSLLNRRQEERLREQEERLHEQE-ERLHEQEERLCEQEERLCEQEERLREQEE 241
Query: 550 QLDEENSELRSCTPCLKANIERL--------EEEK----QKLLDEIESLTLRLSEEQENK 597
+L E+ L L ERL E+EK ++LL+E+E L L QE +
Sbjct: 242 RLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPGQERLLEEVEKL-LEQERRQEEQ 300
Query: 598 RRMGDR----------LSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSS 647
R+ +R L ER + Q ++ QE + +L + E +L +LE + R
Sbjct: 301 ERLLERERLLDEVEELLEQERLRQQDERLWQQETLRELERLRELERLRELERLRELERML 360
Query: 648 SMGLQE-YHSRARESELEQEVRRLKQDNRNLKEQNEEL 684
+G + Y RA +E+ + L++Q +EL
Sbjct: 361 ELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKEL 398
Score = 43.5 bits (101), Expect = 7e-04
Identities = 67/280 (23%), Positives = 115/280 (41%), Gaps = 40/280 (14%)
Query: 470 ERRVLELEKDTAATGEQHSR------LRQENLQLVHRANALEEQLKEQELR---ACEMVL 520
+++V DTA +G HS + E LE Q +E + + ++
Sbjct: 47 KKKVNGSSPDTATSGGYHSPGDSATGIYGEGRASSTTLQDLESQYQELAVALDSSSAIIS 106
Query: 521 EETRRQKELLCKMEREKSIEI---ENLQTRLQQLDEENSE-LRSCTPCLKANIERLEEEK 576
+ T L+ + EK EI + L L +L + +E L P + +E+L++E
Sbjct: 107 QLTENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDET 166
Query: 577 QKLLDEIESLTLRLSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLK 636
L E+ES+ +L E EN + + L + R + E LR+Q E L
Sbjct: 167 NHLRKELESVGRQLQAEVENNQMLS--LLNRRQE------------ERLREQEERLH--- 209
Query: 637 LEAEQRRGRSSSMGLQEYHSRARESELEQEVRRLKQDNRNLKEQNEELNGQIITLSIQGA 696
E E+R + QE +E L ++ RL++ L+EQ E L+ Q L Q
Sbjct: 210 -EQEER------LHEQEERLCEQEERLCEQEERLREQEERLREQEERLHEQEERLCEQEE 262
Query: 697 KSLFSTAFSESLAAEISSVSRDELMEAIQKQEEINFRLQD 736
+ E L + ++ L+E ++K E R ++
Sbjct: 263 RLCEQ---EERLCEQEKLPGQERLLEEVEKLLEQERRQEE 299
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 63.9 bits (154), Expect = 5e-10
Identities = 66/213 (30%), Positives = 72/213 (33%), Gaps = 57/213 (26%)
Query: 6 PASPPGSEPPGPDPEPGGPDG-PGAAQLA----------PGPAELRLGAPVGGPDPQSPG 54
P+ PPG P DP P GP G PG A PGP E GG P PG
Sbjct: 1372 PSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGE-------GGIAPGEPG 1424
Query: 55 LDEPAPGAAADGGARWSAGP-------------APGLEGGPRDP---GPSAPPPRSGPRG 98
L PG G + GP APGL G P P GP PP GP+G
Sbjct: 1425 L----PGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKG 1480
Query: 99 QLASPDAPG----------PGPRSEAPLPELDPLFSWTEEPEECGPASCPESAPFRLQGS 148
P G PGP LP + P GP P P QG
Sbjct: 1481 DRGFPGPLGEAGEKGERGPPGPAGSRGLPGV------AGRPGAKGPEGPP--GPTGRQGE 1532
Query: 149 SSSHRARGEVDVFSPFPAPTAGELALEQGPGSP 181
G+ V P A GE + GP P
Sbjct: 1533 KGEPGRPGDPAVVGPAVAGPKGEKG-DVGPAGP 1564
Score = 61.2 bits (147), Expect = 3e-09
Identities = 72/229 (31%), Positives = 83/229 (36%), Gaps = 46/229 (20%)
Query: 14 PPGPDPEPGGPDGPGAAQLAPGPAELRLGAPVGGPDPQSPGLDEPA------PGAAADGG 67
P G EPG G Q+ P P + L G P PQ P A PGA G
Sbjct: 1252 PKGQKGEPGEMGLRG--QVGP-PGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPG 1308
Query: 68 ARWSAGP-----APGLEGGPRDPGPSAPPPRSGPRGQLASPDAPGPGPRSEAP-LP--EL 119
+ AG APGL+G P PGP P GPRG P APG E P LP +
Sbjct: 1309 SPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKG 1368
Query: 120 DPLFSWTEEPE----ECGPASCPESAPFRLQGSSSSHRARGEVDVFSPFPAPTAGELAL- 174
DP S P + GP P ++G RG P P G +A
Sbjct: 1369 DPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGP-------PGPGEGGIAPG 1421
Query: 175 ------------EQGPGSPP----QPSDLSQTHP-LPSEPVGSQEDGPR 206
QGP PP + D P LP +P E GPR
Sbjct: 1422 EPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPR 1470
Score = 55.5 bits (132), Expect = 2e-07
Identities = 39/111 (35%), Positives = 49/111 (44%), Gaps = 12/111 (10%)
Query: 7 ASPPG-SEPPGPDPEPGGPDGPGAAQLAPGPAELRLGAPVGGPDPQSPGLDEPAPGAAAD 65
A PPG S PPG +PG P PG + P + +G P PGL PG A +
Sbjct: 1603 AGPPGDSGPPGEKGDPGRPGPPGP--VGPRGRDGEVGEKGDEGPPGDPGL----PGKAGE 1656
Query: 66 GGARWSAGPA-----PGLEGGPRDPGPSAPPPRSGPRGQLASPDAPGPGPR 111
G R + G G +G P + G + P SGP+G P PGP R
Sbjct: 1657 RGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGR 1707
Score = 55.1 bits (131), Expect = 2e-07
Identities = 39/109 (35%), Positives = 49/109 (44%), Gaps = 10/109 (9%)
Query: 15 PGPDPEPGGPDGPGAAQLAPGPAELRLGAPVGGPDPQSPGLDEPAPGAAADGGARWSAGP 74
PGP + G P PG +A + L P G P P D PGA G GP
Sbjct: 2143 PGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGP 2202
Query: 75 APGLEGGPRDPGPSAPPPR--SGPRGQLASPDAPGP----GPRSEAPLP 117
+ GL+G +PG + PP R +GP G + P PGP GP+ LP
Sbjct: 2203 S-GLKG---EPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLP 2247
Score = 53.9 bits (128), Expect = 5e-07
Identities = 61/188 (32%), Positives = 71/188 (37%), Gaps = 39/188 (20%)
Query: 15 PGP-----DPEPGGPDGPGAAQLAPGPAELR--LGAP--------VGGPDPQSPGLDEPA 59
PGP DP G P PG PGP ++ LG P VG P P +
Sbjct: 2362 PGPKGFKGDPGVGVPGSPGP----PGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQ 2417
Query: 60 PGAAADGGARWSAGPA-----PGLEGGPRDPGPSAPPPRSGPRGQLASPDAPGPGPRSEA 114
PG + G R AGP PG G P PG PP SG +G P PGPR E
Sbjct: 2418 PGPS---GERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGER 2474
Query: 115 PLPELDPLFSWTEEPEECGPASCPESAPFRLQGSSSSHRARGEV-DVFSPFPAPTAGELA 173
P + E+ P + P L G S RGE DV S G+ A
Sbjct: 2475 GEPGI--------RGEDGRPG---QEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSA 2523
Query: 174 LEQGPGSP 181
+ GP P
Sbjct: 2524 VILGPPGP 2531
Score = 52.8 bits (125), Expect = 1e-06
Identities = 66/230 (28%), Positives = 79/230 (34%), Gaps = 52/230 (22%)
Query: 6 PASPPGSEPPGPDPEPGGPDGPGAAQLAPGPAELRLGAP-------VGGPDPQSP-GLDE 57
P SP P GP EPG PG A + A+ GAP VG P + GL
Sbjct: 2277 PGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPG 2336
Query: 58 P-----------APGAAADGGARWSAGPA-----PGLEGGPRDPGPSAPPPRSGPRGQLA 101
P PG + G + + GP PG+ G P PGP PP G G
Sbjct: 2337 PRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGV-GVPGSPGPPGPPGVKGDLGLPG 2395
Query: 102 SPDAPG----------------PGPRSEAPL---PELDPLFSWTEEPEECGPASCPESAP 142
P APG PGP E L P + + P GP P S
Sbjct: 2396 LPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGI------PGPLGPPGPPGSV- 2448
Query: 143 FRLQGSSSSHRARGEVDVFSPFPAPTAGELALEQGPGSPPQPSDLSQTHP 192
G+S +G+ V P P GE + G P Q T P
Sbjct: 2449 -GPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGP 2497
Score = 51.6 bits (122), Expect = 3e-06
Identities = 63/218 (28%), Positives = 73/218 (33%), Gaps = 36/218 (16%)
Query: 6 PASPPGSEPPGPDPEPGGPDGPGAAQLAPGPAELRLGAPVGGPDPQSPGLDEPAPGAAAD 65
P PPG P G E G P PG + GPA + P G P A G +
Sbjct: 1520 PEGPPG--PTGRQGEKGEPGRPGDPAVV-GPA---VAGPKGEKGDVGPAGPRGATGVQGE 1573
Query: 66 GGARWSAGPA-PGLEGGPRDPGP------SAPPPRSGPRGQLASPDAPGP----GPRSEA 114
G P PG +G P D GP + PP SGP G+ P PGP GPR
Sbjct: 1574 RGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRD 1633
Query: 115 PLPELDPLFSWTEEPEECGPASCPESAPFRLQGSSSSHRARGEVDVFSPF----PAPTAG 170
E + GP P L G + RG V P G
Sbjct: 1634 ---------GEVGEKGDEGPPGDP-----GLPGKAGERGLRGAPGVRGPVGEKGDQGDPG 1679
Query: 171 ELALEQGPGSPPQPSDLSQTHPLPSEPVGSQEDGPRLR 208
E PGS D + P P P + GP R
Sbjct: 1680 EDGRNGSPGSSGPKGDRGEPGP-PGPPGRLVDTGPGAR 1716
Score = 50.4 bits (119), Expect = 6e-06
Identities = 47/141 (33%), Positives = 52/141 (36%), Gaps = 28/141 (19%)
Query: 5 PPASPPGSEPPGPDPEPG-----GPDGPGAAQLAPG---PAELRLGAPVG--------GP 48
PP G PGP PG GP GP + PG P L P G GP
Sbjct: 2175 PPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGP 2234
Query: 49 D----PQ-SPGL-----DEPAPGAAADGGARWSAGP--APGLEGGPRDPGPSAPPPRSGP 96
PQ SPGL + PGA GA G +PG+ G P PGP P GP
Sbjct: 2235 SGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGP 2294
Query: 97 RGQLASPDAPGPGPRSEAPLP 117
G PG + E P
Sbjct: 2295 TGAPGQAVVGLPGAKGEKGAP 2315
Score = 48.9 bits (115), Expect = 2e-05
Identities = 62/201 (30%), Positives = 71/201 (35%), Gaps = 31/201 (15%)
Query: 4 APPASPPGSE----PPGP-----DPEPGGPDGPGAAQLAPGPAELRLGAPVGGPDPQSPG 54
A P PG + PPGP DP P G G GP+ L+ G P G P G
Sbjct: 2161 AGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLK-GEP-GETGPPGRG 2218
Query: 55 LDEP--APGAAADGGARWSAGP--APGLEGGPRDPGPSAPPPRSGPRGQ---------LA 101
L P A G G GP +PGL G + G P R G G+
Sbjct: 2219 LTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPG 2278
Query: 102 SPDAPGP-GPRSEAPLPELDPLFSWTEEPEECGPASCPESAPFRLQGSSSSHRARGEVDV 160
SP PGP GP+ E P P P + P G P L G + RG
Sbjct: 2279 SPGLPGPVGPKGE-PGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRG---- 2333
Query: 161 FSPFPAPTAGELALEQGPGSP 181
P P GE PG P
Sbjct: 2334 -LPGPRGEKGEAGRAGEPGDP 2353
Score = 48.1 bits (113), Expect = 3e-05
Identities = 47/147 (31%), Positives = 53/147 (36%), Gaps = 34/147 (23%)
Query: 5 PPASPPGSEPPGPDPEPGGPDGPGAAQLAPGP-------AELRLGAPVGGPDPQSPGLDE 57
PP G PG PG P PG Q GP + GAP P SPG
Sbjct: 1410 PPGPGEGGIAPGEPGLPGLPGSPG-PQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQG 1468
Query: 58 P--APGA---------------AADGGARWSAGPA-----PGLEGGPRDPGPSAPPPRSG 95
P PGA A + G R GPA PG+ G P GP PP +G
Sbjct: 1469 PRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTG 1528
Query: 96 PRGQLASPDAPGP----GPRSEAPLPE 118
+G+ P PG GP P E
Sbjct: 1529 RQGEKGEPGRPGDPAVVGPAVAGPKGE 1555
Score = 48.1 bits (113), Expect = 3e-05
Identities = 67/234 (28%), Positives = 82/234 (35%), Gaps = 51/234 (21%)
Query: 7 ASPPGSE----PPGPDPEPGGPDGPGAAQL----------APGPAELRLGAPVGGPDPQS 52
A PPG E P GP PG PGA+ L PGP R + G D +
Sbjct: 2427 AGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGR- 2485
Query: 53 PGLDEP-----APGAAADGGARWSAGPAPGLEG------------GPR-------DPGPS 88
PG + P PG+ + G + G A GL+G GPR + GP
Sbjct: 2486 PGQEGPRGLTGPPGSRGERGEKGDVGSA-GLKGDKGDSAVILGPPGPRGAKGDMGERGPR 2544
Query: 89 APPPRSGPRGQLASPDAPG----PGPRSEAPLPELDPLFSWTEEPEECGPASCPESAPFR 144
GPRG P G PG + A LP L L +P G P S
Sbjct: 2545 GLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGS---- 2600
Query: 145 LQGSSSSHRARGEV-DVFSPFPAPTAGELALEQGPGSPPQPSDLSQTHPLPSEP 197
G RGE DV P GE ++ G + D + P P P
Sbjct: 2601 -PGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGP-PGRP 2652
Score = 47.4 bits (111), Expect = 5e-05
Identities = 60/220 (27%), Positives = 72/220 (32%), Gaps = 43/220 (19%)
Query: 5 PPASPPGSEPPGPDPEPGGPDGPG---AAQLAPGPAELRLGAPVGGPDPQSPGLDEPAPG 61
PP P PPGP D PG + + P + G P G Q P D PG
Sbjct: 2077 PPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEP-GSNGDQGPKGDRGVPG 2135
Query: 62 AAADGGARWSAGP--APGL---------EGGPRDPGPSAPPPRSGPRGQLASPDAPG--- 107
D G G PGL EG P GP PP G G P APG
Sbjct: 2136 IKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAG 2195
Query: 108 -PGPRSEAPLPELDPLFSWTEEPEECGPASCPESAPFRLQGSSSSHRARGEVDVFSPFPA 166
GP+ + L EP E GP + P G P P
Sbjct: 2196 PAGPQGPSGL---------KGEPGETGPPGRGLTGPTGAVG--------------LPGPP 2232
Query: 167 PTAGELALEQGPGSPPQPSDLSQTHPLPSEPVGSQEDGPR 206
+G + + PG P Q + + P S +DG R
Sbjct: 2233 GPSGLVGPQGSPGLPGQVGETGKP-GAPGRDGASGKDGDR 2271
Score = 46.6 bits (109), Expect = 9e-05
Identities = 62/217 (28%), Positives = 74/217 (34%), Gaps = 38/217 (17%)
Query: 9 PPGSEPP------------GPDPEPGGPDGPGAAQLAP-GPAELRLGAPVGGPDPQSPGL 55
PPG E P DP P GP G + P GP+ L G P P PG
Sbjct: 1989 PPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLA-GEPGKPGIPGLPGR 2047
Query: 56 -----DEPAPGAAADGGARWSAGPAPGLEGGPRDPGPSAPPPRSGPRGQLASPDAPGPGP 110
+ PG + G + G G +G P PG PP GP G S D PGPG
Sbjct: 2048 AGGVGEAGRPGERGERGEKGERGEQ-GRDGPPGLPGTPGPP---GPPGPKVSVDEPGPGL 2103
Query: 111 RSEAPLPELDPLFSWTEEPEECGPASCPESAPFRLQGSSSSHRARGEVDVFSPFPAPTAG 170
E P L + + P S + P +G RGE P P G
Sbjct: 2104 SGEQGPPGL--------KGAKGEPGSNGDQGPKGDRGVPGIKGDRGE-----PGPRGQDG 2150
Query: 171 ELAL--EQGPGSPPQPSDLSQTHPLPSEPVGSQEDGP 205
L E+G P L P G + GP
Sbjct: 2151 NPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGP 2187
Score = 46.2 bits (108), Expect = 1e-04
Identities = 58/196 (29%), Positives = 72/196 (36%), Gaps = 35/196 (17%)
Query: 9 PPGSEP-PGPDPEPG--GPDGP-GAAQLAPGPA---------ELRLGAPVGGPD-PQSPG 54
PPG + G D +PG GP GP GAA A P E L P G P P PG
Sbjct: 1774 PPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPG 1833
Query: 55 LDEPAPGAAADGGARWSAGPAPGLEGGPRDPGPSAPPPRSGPRGQLASPDAPGPGPRSEA 114
++ PG G G G +G D G S R GP+G+ +P GP
Sbjct: 1834 -EDGKPGLNGKNGEPGDPGE-DGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGL 1891
Query: 115 PLPELDPLFSWTEEPEECGPASCPESAPFRLQGSSSSHRARGEVDVFSPFPAPTAGELAL 174
P P P + P GP +G ++GE + GE L
Sbjct: 1892 PGPVGPPGQGFPGVPGGTGP-----------KGDRGETGSKGEQGL--------PGERGL 1932
Query: 175 EQGPGSPPQPSDLSQT 190
PGS P L +T
Sbjct: 1933 RGEPGSVPNVDRLLET 1948
Score = 42.7 bits (99), Expect = 0.001
Identities = 77/265 (29%), Positives = 97/265 (36%), Gaps = 76/265 (28%)
Query: 3 SAPP--ASPPGSE-------PPGP------DPEPG--GPDGPGAAQLAPGPAELR--LGA 43
+ PP + PPG + PPGP D E G G +GP PG A R GA
Sbjct: 1603 AGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGA 1662
Query: 44 P-VGGP-----DPQSPGLD--EPAPGAAADGGARWSAGP----------APGL--EGGPR 83
P V GP D PG D +PG++ G R GP PG +G P
Sbjct: 1663 PGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPG 1722
Query: 84 DPGPSAPPPRSGPRGQLASPDAPG----------PGPRSEAPL------------PELDP 121
D G P GP+G P APG PGP+ + + P LD
Sbjct: 1723 DRGQEGP---RGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDG 1779
Query: 122 LFSWTEEPEECGPASCPESAPFRL--QGSSSSHRARGEVDVFSPFPAPTAGELALEQGPG 179
+P GP S P A + G RGE + P +G L PG
Sbjct: 1780 RSGLDGKPGAAGP-SGPNGAAGKAGDPGRDGLPGLRGEQGLPGP-----SGPPGLPGKPG 1833
Query: 180 SPPQPSDLSQTHPLPSEPVGSQEDG 204
+P L+ + P +P EDG
Sbjct: 1834 EDGKPG-LNGKNGEPGDP---GEDG 1854
Score = 42.4 bits (98), Expect = 0.002
Identities = 61/223 (27%), Positives = 73/223 (32%), Gaps = 58/223 (26%)
Query: 15 PGPDPEPGGPDGPGAAQLAPGPAELRLGAPVGGP-------DPQSPGLDEPAPGAAADGG 67
PG G P G+A L P L P G P DP SPG D PG + G
Sbjct: 2559 PGDKGSKGEPGDKGSAGL---PGLRGLLGPQGQPGAAGIPGDPGSPGKDG-VPGIRGEKG 2614
Query: 68 ARWSAGP-----------APGLEGGPRDPGPSAPPPR---SGPRGQLASPDAPG------ 107
GP A GL+G D G + PP R +G +G++ P PG
Sbjct: 2615 DVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPG 2674
Query: 108 ----------------PGP------RSEAPLPELDPLFSWTEEPEECGPASCPES----A 141
PGP + E P + + GP P S
Sbjct: 2675 KEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRG 2734
Query: 142 PFRLQGSSSSHRARGEVDVFSPFPAPTAGELALEQGPGSPPQP 184
P LQG GE V +P GE EQG P P
Sbjct: 2735 PEGLQGQKGERGPPGERVVGAPGVPGAPGERG-EQGRPGPAGP 2776
Score = 35.4 bits (80), Expect = 0.20
Identities = 27/94 (28%), Positives = 35/94 (37%), Gaps = 7/94 (7%)
Query: 6 PASPPGSEPPGPDPEPGGPDGPGAAQLAPGPAELRLGAPVGGPDPQSPGLDEPAPGAAAD 65
P G + P GG GP + GP P G P+ P + G
Sbjct: 2693 PKGDQGEKGERGTPGIGGFPGPSGNDGSAGPP-----GPPGSVGPRGPEGLQGQKGERGP 2747
Query: 66 GGARWSAGPAPGLEGGPRDPGPSAPPPRSGPRGQ 99
G R APG+ G P + G P +GPRG+
Sbjct: 2748 PGERVVG--APGVPGAPGERGEQGRPGPAGPRGE 2779
Score = 31.2 bits (69), Expect = 3.7
Identities = 43/160 (26%), Positives = 49/160 (30%), Gaps = 57/160 (35%)
Query: 6 PASPPGSEPPGPDPEPGGPDGPGAA--------------QLAPGPAELRLGAPVGGPD-- 49
P PPG P P G P PG Q PG LR G P P+
Sbjct: 1885 PQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLR-GEPGSVPNVD 1943
Query: 50 --------------------PQSPGLDEPAP-------GAAADGGARWSAGP-----APG 77
+S G P P G + + G GP G
Sbjct: 1944 RLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERG 2003
Query: 78 LEGGPRDPGPSAPPPRS-------GPRGQLASPDAPG-PG 109
L+G DPGP PP + GP G P PG PG
Sbjct: 2004 LKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPG 2043
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 63.9 bits (154), Expect = 5e-10
Identities = 82/336 (24%), Positives = 145/336 (43%), Gaps = 35/336 (10%)
Query: 431 KVARYLHQSGALTMEALEDP--SPELMEGPEEDIADKVVFLERRVLELEKDTAATGEQHS 488
KV R L A E E S E + D+++++ L+ + + TAA E +
Sbjct: 1111 KVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRT 1170
Query: 489 RLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELLCKMEREKSIEIENLQTRL 548
+ QE +L ALEE+ K E + +M +EL ++E+ K + NL+
Sbjct: 1171 KREQEVAEL---KKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKA-NLEKNK 1226
Query: 549 QQLDEENSELRSCTPCLKANIERLEEEKQKLLD-EIESLTLRLSEEQENKRRMGDRLSHE 607
Q L+ +N EL +C + ++ E K+K LD +++ L ++SE R+ L+ +
Sbjct: 1227 QGLETDNKEL-ACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGD----RLRVELAEK 1281
Query: 608 RHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARESELEQEV 667
+ Q + + L+E+ K + ++ K A + L + +R ++ L +
Sbjct: 1282 ASKLQNELDNVSTLLEEAEK--KGIKFAKDAASLESQLQDTQELLQEETR-QKLNLSSRI 1338
Query: 668 RRLKQDNRNLKEQNEE-------LNGQIITLSIQGA-------------KSLFSTAFSES 707
R+L+++ +L+EQ EE L Q++ L Q A +SL
Sbjct: 1339 RQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLL 1398
Query: 708 LAAEISSVSRDELMEAIQKQEEINFRLQDYIDRIIV 743
AE S +E A K E+ RLQ +D + V
Sbjct: 1399 KDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTV 1434
Score = 58.9 bits (141), Expect = 2e-08
Identities = 57/228 (25%), Positives = 109/228 (47%), Gaps = 13/228 (5%)
Query: 477 EKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELLCKMERE 536
EK T GE + +++ QL+ N L EQL+ + E+ E + L K +
Sbjct: 866 EKQTKVEGELEE-MERKHQQLLEEKNILAEQLQAET----ELFAEAEEMRARLAAKKQEL 920
Query: 537 KSIEIENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLRLSEEQEN 596
+ I + +L++R+++ +E N L++ ++A+I+ LEE+ + + L L +
Sbjct: 921 EEI-LHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAK 979
Query: 597 KRRMGDR---LSHERHQFQRDKEATQELIEDLRKQL-EHLQLLKLEAEQRRGRSSSMGLQ 652
++M + L + +F ++K+ ++ I + QL E + K A+ R + +
Sbjct: 980 IKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDL 1039
Query: 653 EYHSRARE---SELEQEVRRLKQDNRNLKEQNEELNGQIITLSIQGAK 697
E + E ELE+ R+L + +L++Q EL QI L +Q AK
Sbjct: 1040 EERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAK 1087
Score = 57.8 bits (138), Expect = 4e-08
Identities = 66/307 (21%), Positives = 142/307 (46%), Gaps = 29/307 (9%)
Query: 453 ELMEGPEEDIADKVVFLERRVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQE 512
E M E++ D++ E L LE + A Q R +LQ N +++L ++
Sbjct: 1542 EEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFER----DLQTRDEQNEEKKRLLIKQ 1597
Query: 513 LRACEMVLEETRRQKELLCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKANIERL 572
+R E LE+ R+Q+ L +++ I++++L+ +++ ++ E+ I++L
Sbjct: 1598 VRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEV----------IKQL 1647
Query: 573 EEEKQKLLDEIESLTLRLSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHL 632
+ + ++ D E E R D + + + ++ ++ + I L+++L
Sbjct: 1648 RKLQAQMKD--------YQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASS 1699
Query: 633 QLLKLEAEQRRGRSSSMGLQEYHSRARESELEQEVRRLKQDNRNLKEQNEELNGQIITLS 692
+ + AEQ R + + +S + +S L E RRL+ L+E+ EE + L+
Sbjct: 1700 ERARRHAEQER---DELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLN 1756
Query: 693 IQGAKSLFST-AFSESLAAEISSVSR-DELMEAIQKQ-EEINFRLQDYIDRIIVAIMETN 749
+ K+ + LAAE S+ + D + +++Q +E+ +LQ+ ++ + + +
Sbjct: 1757 DRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQE-LEGAVKSKFKAT 1815
Query: 750 PSILEVK 756
S LE K
Sbjct: 1816 ISALEAK 1822
Score = 53.9 bits (128), Expect = 5e-07
Identities = 44/224 (19%), Positives = 113/224 (50%), Gaps = 20/224 (8%)
Query: 519 VLEETRRQKELLCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQK 578
+L+ TR+++EL K E+ ++++ QT+++ EE ++ ++L EEK
Sbjct: 844 LLQVTRQEEELQAK--DEELLKVKEKQTKVEGELEE----------MERKHQQLLEEKNI 891
Query: 579 LLDEIESLTLRLSEEQENKRRMG------DRLSHERHQFQRDKEATQELIEDLRKQLE-H 631
L +++++ T +E +E + R+ + + H+ ++E +++++ +K+++ H
Sbjct: 892 LAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAH 951
Query: 632 LQLLKLEAEQRRGRSSSMGLQEYHSRARESELEQEVRRLKQDNRNLKEQNEELNGQIITL 691
+Q L+ + ++ G + L++ + A+ ++E+E+ L+ N ++ + + +I
Sbjct: 952 IQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAEC 1011
Query: 692 SIQGAKSLFSTAFSESLAAEISSVSRDELMEAIQKQEEINFRLQ 735
S Q A+ A + + V +L E ++K+E+ L+
Sbjct: 1012 SSQLAEE-EEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELE 1054
Score = 53.9 bits (128), Expect = 5e-07
Identities = 67/307 (21%), Positives = 136/307 (44%), Gaps = 51/307 (16%)
Query: 474 LELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELLCKM 533
L+ E D +T + + ++ ++ A +LE QL++ + E++ EETR++ L ++
Sbjct: 1285 LQNELDNVSTLLEEAE--KKGIKFAKDAASLESQLQDTQ----ELLQEETRQKLNLSSRI 1338
Query: 534 EREKSIEIENLQTRLQQLDEENSELRSCTPCLKAN--------------IERLEEEKQKL 579
R+ E +LQ + ++ +E L L++ IE LEE K+KL
Sbjct: 1339 -RQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKL 1397
Query: 580 LDEIESLTLRLSEE---QENKRRMGDRLSHERHQFQRDKEATQELIEDL-RKQLEHLQLL 635
L + E+L+ RL E+ + + +RL E D + +++ +L +KQ + QLL
Sbjct: 1398 LKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLL 1457
Query: 636 ---------------KLEAEQRRGRSSSMGLQEYHSRARES--ELEQEVRRLKQDNRNLK 678
+ EAE R + ++ L A E+ E E++ ++L+ D +L
Sbjct: 1458 AEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLM 1517
Query: 679 EQNEELNGQIITL---------SIQGAKSLFSTAFSESLAAEISSVSRDELMEAIQKQEE 729
+++ + L ++ ++ E A E + + + M+A++ Q E
Sbjct: 1518 SSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFE 1577
Query: 730 INFRLQD 736
+ + +D
Sbjct: 1578 RDLQTRD 1584
Score = 53.5 bits (127), Expect = 7e-07
Identities = 60/257 (23%), Positives = 118/257 (45%), Gaps = 39/257 (15%)
Query: 471 RRVLELE-KDTAATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKEL 529
++ +E++ KD A E ++ R E ++ + L+ Q+K+ + LEE R ++
Sbjct: 1619 KKKMEIDLKDLEAQIEAANKARDE---VIKQLRKLQAQMKDYQRE-----LEEARASRDE 1670
Query: 530 LCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLR 589
+ +E ++++L+ + QL EE + E+E+ +L DEI +
Sbjct: 1671 IFAQSKESEKKLKSLEAEILQLQEELASSERAR-------RHAEQERDELADEITNSASG 1723
Query: 590 LSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSM 649
S + KRR+ R++ + + ++++ EL+ D R + LQ+ L AE RS++
Sbjct: 1724 KSALLDEKRRLEARIAQLEEELE-EEQSNMELLND-RFRKTTLQVDTLNAELAAERSAA- 1780
Query: 650 GLQEYHSRARESELEQEVRRLKQDNRNLKEQNEELNGQIITLSIQGAKSLFSTAFSESLA 709
+ AR+ +L++ N+ LK + +EL G + KS F S +L
Sbjct: 1781 ---QKSDNARQ--------QLERQNKELKAKLQELEGAV--------KSKFKATIS-ALE 1820
Query: 710 AEISSVSRDELMEAIQK 726
A+I + EA ++
Sbjct: 1821 AKIGQLEEQLEQEAKER 1837
Score = 53.1 bits (126), Expect = 9e-07
Identities = 65/315 (20%), Positives = 148/315 (46%), Gaps = 31/315 (9%)
Query: 462 IADKVVFLERRVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLE 521
+A K LE + +LE E++ L+ E ++ LEEQL E+E ++ LE
Sbjct: 913 LAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLE 972
Query: 522 ET------RRQKELLCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKANIERLEEE 575
+ ++ +E + +E + S I+ + ++ E +S+L K N+ ++ +
Sbjct: 973 KVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAK-NLAKIRNK 1031
Query: 576 KQKLLDEIESLTLRLSEEQENKRRMGDRLSHERHQFQRDKEAT--QELIEDLRKQLEHLQ 633
++ ++ ++E RL +E++ ++ + E+ + + D E T Q+ I +L+ Q++ L+
Sbjct: 1032 QEVMISDLEE---RLKKEEKTRQEL------EKAKRKLDGETTDLQDQIAELQAQIDELK 1082
Query: 634 L-LKLEAEQRRGRSSSMGLQEYHS----------RARESELEQEVRRLKQDNRNLKEQNE 682
L L + E+ +G + + H +A+ +EL+++ K ++Q
Sbjct: 1083 LQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKR 1142
Query: 683 ELNGQIITLSIQGAKSLFSTAFSESLAAEISSVSRDELMEAIQKQ-EEINFRLQDYIDRI 741
+L+ ++ L + +L +TA + L + EL +A++++ + ++QD R
Sbjct: 1143 DLSEELEALKTELEDTLDTTAAQQELRTK-REQEVAELKKALEEETKNHEAQIQDMRQRH 1201
Query: 742 IVAIMETNPSILEVK 756
A+ E + + + K
Sbjct: 1202 ATALEELSEQLEQAK 1216
Score = 50.8 bits (120), Expect = 5e-06
Identities = 49/239 (20%), Positives = 106/239 (44%), Gaps = 30/239 (12%)
Query: 470 ERRVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKEL 529
E + +LE+ + L + +L L++Q+ E + + E+ L+ ++++EL
Sbjct: 1033 EVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEEL 1092
Query: 530 LCKMER--EKSIEIENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESL- 586
+ R ++++ N +++L + +EL+ KA+ + E++K+ L +E+E+L
Sbjct: 1093 QGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALK 1152
Query: 587 -----------------TLRLSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQL 629
T R E E K+ + + + Q Q ++ +E+L +QL
Sbjct: 1153 TELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQL 1212
Query: 630 EHLQLLKLEAEQRRGRSSSMGLQEYHSRARESELEQEVRRLKQDNRNLKEQNEELNGQI 688
E + K E+ + GL+ EL EV+ L+Q + + ++L+ Q+
Sbjct: 1213 EQAKRFKANLEKNK-----QGLE-----TDNKELACEVKVLQQVKAESEHKRKKLDAQV 1261
Score = 50.8 bits (120), Expect = 5e-06
Identities = 76/317 (23%), Positives = 138/317 (43%), Gaps = 48/317 (15%)
Query: 443 TMEALEDPSPELMEGPE------EDIA---DKVVFLERRVLELEKDTAATGEQHSRLRQE 493
T+E+LE+ +L++ E E+ A DK+ + R L+ E D H R
Sbjct: 1386 TIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNR-LQQELDDLTVDLDHQRQVAS 1444
Query: 494 NL--------QLVHRANALEEQLKEQELRACEMVLEETRRQKE---LLCKMEREKSIEI- 541
NL QL+ ++ + E+ RA E R+KE L E+++E
Sbjct: 1445 NLEKKQKKFDQLLAEEKSISARYAEERDRA-----EAEAREKETKALSLARALEEALEAK 1499
Query: 542 ENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLRLSEEQEN----- 596
E + + +QL + +L S + N+ LE+ K+ L ++E + +L E ++
Sbjct: 1500 EEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATE 1559
Query: 597 --KRRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAE------QRRGRSSS 648
K R+ + + QF+RD + E E+ +K+L Q+ +LEAE QR +S
Sbjct: 1560 DAKLRLEVNMQAMKAQFERDLQTRDEQNEE-KKRLLIKQVRELEAELEDERKQRALAVAS 1618
Query: 649 MGLQEYHSRARESELE-------QEVRRLKQDNRNLKEQNEELNGQIITLSIQGAKSLFS 701
E + E+++E + +++L++ +K+ EL + A+S S
Sbjct: 1619 KKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKES 1678
Query: 702 TAFSESLAAEISSVSRD 718
+SL AEI + +
Sbjct: 1679 EKKLKSLEAEILQLQEE 1695
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.131 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,397,107
Number of Sequences: 37866
Number of extensions: 2735842
Number of successful extensions: 46427
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 683
Number of HSP's successfully gapped in prelim test: 2798
Number of HSP's that attempted gapping in prelim test: 15996
Number of HSP's gapped (non-prelim): 15835
length of query: 756
length of database: 18,247,518
effective HSP length: 110
effective length of query: 646
effective length of database: 14,082,258
effective search space: 9097138668
effective search space used: 9097138668
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.