Guide to the Human Genome
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Search of human proteins with 7662146

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7662146 DnaJ (Hsp40) homolog, subfamily C, member 6 [Homo
sapiens]
         (913 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7662146 DnaJ (Hsp40) homolog, subfamily C, member 6 [Homo sap...  1889   0.0  
gi|157384971 cyclin G associated kinase [Homo sapiens]                775   0.0  
gi|65288071 tensin 3 [Homo sapiens]                                   121   3e-27
gi|38787970 tensin like C1 domain containing phosphatase isoform...   120   4e-27
gi|38787957 tensin like C1 domain containing phosphatase isoform...   120   4e-27
gi|38787941 tensin like C1 domain containing phosphatase isoform...   120   4e-27
gi|66529407 tensin [Homo sapiens]                                     120   8e-27
gi|73765544 phosphatase and tensin homolog [Homo sapiens]             109   1e-23
gi|213972593 TPTE and PTEN homologous inositol lipid phosphatase...   103   1e-21
gi|213972591 TPTE and PTEN homologous inositol lipid phosphatase...   103   1e-21
gi|213972589 TPTE and PTEN homologous inositol lipid phosphatase...   103   1e-21
gi|40549435 transmembrane phosphatase with tensin homology isofo...    97   5e-20
gi|40549433 transmembrane phosphatase with tensin homology isofo...    97   5e-20
gi|109689707 transmembrane phosphatase with tensin homology isof...    97   5e-20
gi|163965366 nascent polypeptide-associated complex alpha subuni...    58   5e-08
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     55   2e-07
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ...    55   3e-07
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ...    55   3e-07
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    54   7e-07
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ...    54   9e-07
gi|54860079 nadrin isoform 1 [Homo sapiens]                            52   3e-06
gi|54860105 nadrin isoform 2 [Homo sapiens]                            52   3e-06
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi...    51   4e-06
gi|7662228 synaptosomal-associated protein, 91kDa homolog [Homo ...    51   6e-06
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H...    51   6e-06
gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens]    50   7e-06
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]             49   2e-05
gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]    49   2e-05
gi|39995080 hypothetical protein LOC79567 [Homo sapiens]               49   2e-05
gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]           47   6e-05

>gi|7662146 DnaJ (Hsp40) homolog, subfamily C, member 6 [Homo
           sapiens]
          Length = 913

 Score = 1889 bits (4892), Expect = 0.0
 Identities = 913/913 (100%), Positives = 913/913 (100%)

Query: 1   MKDSENKGASSPDMEPSYGGGLFDMVKGGAGRLFSNLKDNLKDTLKDTSSRVIQSVTSYT 60
           MKDSENKGASSPDMEPSYGGGLFDMVKGGAGRLFSNLKDNLKDTLKDTSSRVIQSVTSYT
Sbjct: 1   MKDSENKGASSPDMEPSYGGGLFDMVKGGAGRLFSNLKDNLKDTLKDTSSRVIQSVTSYT 60

Query: 61  KGDLDFTYVTSRIIVMSFPLDNVDIGFRNQVDDIRSFLDSRHLDHYTVYNLSPKSYRTAK 120
           KGDLDFTYVTSRIIVMSFPLDNVDIGFRNQVDDIRSFLDSRHLDHYTVYNLSPKSYRTAK
Sbjct: 61  KGDLDFTYVTSRIIVMSFPLDNVDIGFRNQVDDIRSFLDSRHLDHYTVYNLSPKSYRTAK 120

Query: 121 FHSRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDGRAASSILVGAMFI 180
           FHSRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDGRAASSILVGAMFI
Sbjct: 121 FHSRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDGRAASSILVGAMFI 180

Query: 181 FCNLYSTPGPAIRLLYAKRPGIGLSPSHRRYLGYMCDLLADKPYRPHFKPLTIKSITVSP 240
           FCNLYSTPGPAIRLLYAKRPGIGLSPSHRRYLGYMCDLLADKPYRPHFKPLTIKSITVSP
Sbjct: 181 FCNLYSTPGPAIRLLYAKRPGIGLSPSHRRYLGYMCDLLADKPYRPHFKPLTIKSITVSP 240

Query: 241 IPFFNKQRNGCRPYCDVLIGETKIYSTCTDFERMKEYRVQDGKIFIPLNITVQGDVVVSM 300
           IPFFNKQRNGCRPYCDVLIGETKIYSTCTDFERMKEYRVQDGKIFIPLNITVQGDVVVSM
Sbjct: 241 IPFFNKQRNGCRPYCDVLIGETKIYSTCTDFERMKEYRVQDGKIFIPLNITVQGDVVVSM 300

Query: 301 YHLRSTIGSRLQAKVTNTQIFQLQFHTGFIPLDTTVLKFTKPELDACDVPEKYPQLFQVT 360
           YHLRSTIGSRLQAKVTNTQIFQLQFHTGFIPLDTTVLKFTKPELDACDVPEKYPQLFQVT
Sbjct: 301 YHLRSTIGSRLQAKVTNTQIFQLQFHTGFIPLDTTVLKFTKPELDACDVPEKYPQLFQVT 360

Query: 361 LDVELQPHDKVIDLTPPWEHYCTKDVNPSILFSSHQEHQDTLALGGQAPIDIPPDNPRHY 420
           LDVELQPHDKVIDLTPPWEHYCTKDVNPSILFSSHQEHQDTLALGGQAPIDIPPDNPRHY
Sbjct: 361 LDVELQPHDKVIDLTPPWEHYCTKDVNPSILFSSHQEHQDTLALGGQAPIDIPPDNPRHY 420

Query: 421 GQSGFFASLCWQDQKSEKSFCEEDHAALVNQESEQSDDELLTLSSPHGNANGDKPHGVKK 480
           GQSGFFASLCWQDQKSEKSFCEEDHAALVNQESEQSDDELLTLSSPHGNANGDKPHGVKK
Sbjct: 421 GQSGFFASLCWQDQKSEKSFCEEDHAALVNQESEQSDDELLTLSSPHGNANGDKPHGVKK 480

Query: 481 PSKKQQEPAAPPPPEDVDLLGLEGSAMSNSFSPPAAPPTNSELLSDLFGGGGAAGPTQAG 540
           PSKKQQEPAAPPPPEDVDLLGLEGSAMSNSFSPPAAPPTNSELLSDLFGGGGAAGPTQAG
Sbjct: 481 PSKKQQEPAAPPPPEDVDLLGLEGSAMSNSFSPPAAPPTNSELLSDLFGGGGAAGPTQAG 540

Query: 541 QSGVEDVFHPSGPASTQSTPRRSATSTSASPTLRVGEGATFDPFGAPSKPSGQDLLGSFL 600
           QSGVEDVFHPSGPASTQSTPRRSATSTSASPTLRVGEGATFDPFGAPSKPSGQDLLGSFL
Sbjct: 541 QSGVEDVFHPSGPASTQSTPRRSATSTSASPTLRVGEGATFDPFGAPSKPSGQDLLGSFL 600

Query: 601 NTSSASSDPFLQPTRSPSPTVHASSTPAVNIQPDVSGGWDWHAKPGGFGMGSKSAATSPT 660
           NTSSASSDPFLQPTRSPSPTVHASSTPAVNIQPDVSGGWDWHAKPGGFGMGSKSAATSPT
Sbjct: 601 NTSSASSDPFLQPTRSPSPTVHASSTPAVNIQPDVSGGWDWHAKPGGFGMGSKSAATSPT 660

Query: 661 GSSHGTPTHQSKPQTLDPFADLGTLGSSSFASKPTTPTGLGGGFPPLSSPQKASPQPMGG 720
           GSSHGTPTHQSKPQTLDPFADLGTLGSSSFASKPTTPTGLGGGFPPLSSPQKASPQPMGG
Sbjct: 661 GSSHGTPTHQSKPQTLDPFADLGTLGSSSFASKPTTPTGLGGGFPPLSSPQKASPQPMGG 720

Query: 721 GWQQGGAYNWQQPQPKPQPSMPHSSPQNRPNYNVSFSAMPGGQNERGKGSSNLEGKQKAA 780
           GWQQGGAYNWQQPQPKPQPSMPHSSPQNRPNYNVSFSAMPGGQNERGKGSSNLEGKQKAA
Sbjct: 721 GWQQGGAYNWQQPQPKPQPSMPHSSPQNRPNYNVSFSAMPGGQNERGKGSSNLEGKQKAA 780

Query: 781 DFEDLLSGQGFNAHKDKKGPRTIAEMRKEEMAKEMDPEKLKILEWIEGKERNIRALLSTM 840
           DFEDLLSGQGFNAHKDKKGPRTIAEMRKEEMAKEMDPEKLKILEWIEGKERNIRALLSTM
Sbjct: 781 DFEDLLSGQGFNAHKDKKGPRTIAEMRKEEMAKEMDPEKLKILEWIEGKERNIRALLSTM 840

Query: 841 HTVLWAGETKWKPVGMADLVTPEQVKKVYRKAVLVVHPDKATGQPYEQYAKMIFMELNDA 900
           HTVLWAGETKWKPVGMADLVTPEQVKKVYRKAVLVVHPDKATGQPYEQYAKMIFMELNDA
Sbjct: 841 HTVLWAGETKWKPVGMADLVTPEQVKKVYRKAVLVVHPDKATGQPYEQYAKMIFMELNDA 900

Query: 901 WSEFENQGQKPLY 913
           WSEFENQGQKPLY
Sbjct: 901 WSEFENQGQKPLY 913


>gi|157384971 cyclin G associated kinase [Homo sapiens]
          Length = 1311

 Score =  775 bits (2000), Expect = 0.0
 Identities = 435/981 (44%), Positives = 583/981 (59%), Gaps = 128/981 (13%)

Query: 20   GGLFDMVKGGAGRLFSNLKDNLKDTLKDTSSRVIQSVTSYTKGDLDFTYVTSRIIVMSFP 79
            GG  D+++GG  RLF+NLKD        TSS+VIQSV +Y KGDLD +Y+TSRI VMSFP
Sbjct: 372  GGFLDILRGGTERLFTNLKD--------TSSKVIQSVANYAKGDLDISYITSRIAVMSFP 423

Query: 80   LDNVDIGFRNQVDDIRSFLDSRHLDHYTVYNLSPKSYRTAKFHSRVSECSWPIRQAPSLH 139
             + V+   +N ++D+R FLDS+H  HY VYNLSP++YR ++FH+RVSEC W  R+AP LH
Sbjct: 424  AEGVESALKNNIEDVRLFLDSKHPGHYAVYNLSPRTYRPSRFHNRVSECGWAARRAPHLH 483

Query: 140  NLFAVCRNMYNWLLQNPKNVCVVHCLDGRAASSILVGAMFIFCNLYSTPGPAIRLLYAKR 199
             L+ +CRNM+ WL Q+ KNVCVVHC+DGRAAS++ V +   FC L+ST   A+ +   KR
Sbjct: 484  TLYNICRNMHAWLRQDHKNVCVVHCMDGRAASAVAVCSFLCFCRLFSTAEAAVYMFSMKR 543

Query: 200  PGIGLSPSHRRYLGYMCDLLADKPYRPHFKPLTIKSITVSPIPFFNKQRNGCRPYCDVLI 259
               G+ PSH+RY+ YMCD++A++P  PH KP+ ++++ ++P+P F+KQR+GCRP+C+V +
Sbjct: 544  CPPGIWPSHKRYIEYMCDMVAEEPITPHSKPILVRAVVMTPVPLFSKQRSGCRPFCEVYV 603

Query: 260  GETKIYSTCTDFERMKEYRVQDGKIFIPLNITVQGDVVVSMYHLRSTIGSRLQAKVTNTQ 319
            G+ ++ ST  ++++M++++++DGK  IPL +TVQGDV++ +YH RST+G RLQAK+ + +
Sbjct: 604  GDERVASTSQEYDKMRDFKIEDGKAVIPLGVTVQGDVLIVIYHARSTLGGRLQAKMASMK 663

Query: 320  IFQLQFHTGFIPLDTTVLKFTKPELDACDVPEKYPQLFQVTLDVELQPHDKVIDLTPPWE 379
            +FQ+QFHTGF+P + T +KF K +LDACD+ EKYP LFQV L+VE++P D+     PPWE
Sbjct: 664  MFQIQFHTGFVPRNATTVKFAKYDLDACDIQEKYPDLFQVNLEVEVEPRDRPSREAPPWE 723

Query: 380  HYCTKDVNPSILFSSHQEHQDTLALGGQAPIDIPPDNPRHY------------------- 420
            +   + +NP ILFSS +E QD L+  G+  +   P +   Y                   
Sbjct: 724  NSSMRGLNPKILFSSREEQQDILSKFGKPELPRQPGSTAQYDAGAGSPEAEPTDSDSPPS 783

Query: 421  ---GQSGFFASLCWQDQK-----SEKSFCEEDHAALV--NQESEQSDDELLTLSSPHGNA 470
                 S F  +L WQ++K     +E +  +E  +AL+    ESE SD+    +SS     
Sbjct: 784  SSADASRFLHTLDWQEEKEAETGAENASSKESESALMEDRDESEVSDEGGSPISSEGQEP 843

Query: 471  NGD-KPHGVKKPSKKQ------QEPAAPPPP----EDVDLLGLEGSAMSNSFSPP---AA 516
              D +P G+     +Q      + PA  P P    + VDLLGL     +    PP    A
Sbjct: 844  RADPEPPGLAAGLVQQDLVFEVETPAVLPEPVPQEDGVDLLGLHSEVGAGPAVPPQACKA 903

Query: 517  PPTNSELLSDLFGGGGAAGPTQAGQSGVEDVF--------HPSGPASTQSTPRRSATSTS 568
            P +N++LLS L G      P  A Q   ED+          P+ P S QSTPR       
Sbjct: 904  PSSNTDLLSCLLG-----PPEAASQGPPEDLLSEDPLLLASPAPPLSVQSTPRG------ 952

Query: 569  ASPTLRVGEGATFDPFGAPSKPSGQ--------DLLGSFLNTSSASSDP-FLQPTRSPSP 619
                   G  A  DPFG     SG         DL G FLN+ S +  P F     +P P
Sbjct: 953  -------GPPAAADPFGPLLPSSGNNSQPCSNPDLFGEFLNSDSVTVPPSFPSAHSAPPP 1005

Query: 620  TVHA------------SSTPAVNIQPDVSGGWDWHAKPGGFGMGSKSAATSPTGSSHGTP 667
            +  A            S   A +  PD+ GGW    +     +    A   P  S  G P
Sbjct: 1006 SCSADFLHLGDLPGEPSKMTASSSNPDLLGGWAAWTETAASAVAPTPATEGPLFSPGGQP 1065

Query: 668  ------THQSKPQTLDPFADLGTLGSSSFASKPTTPTGLGGGFPPLSSPQKASPQPMG-G 720
                     +K Q  DPFADLG L S           G   GFPP     K +  P G  
Sbjct: 1066 APCGSQASWTKSQNPDPFADLGDLSSGL--------QGSPAGFPPGGFIPKTATTPKGSS 1117

Query: 721  GWQ------QGGAYNWQQPQPKPQPSMPHSSPQNRPNYNVSFSAMPGGQNERGKGSSNLE 774
             WQ      QG ++    PQ KP P    +  Q RPNY  +FS + G + ERG  + +  
Sbjct: 1118 SWQTSRPPAQGASW---PPQAKPPPK---ACTQPRPNYASNFSVI-GAREERGVRAPSFA 1170

Query: 775  GKQKAA--DFEDLLSGQGFNAHKDKKGPRTIAEMRKEEMAKEMDPEKLKILEWIEGKERN 832
             K K +  DFEDLLS QGF++  DKKGP+TIAEMRK+++AK+ DP KLK+L+WIEGKERN
Sbjct: 1171 QKPKVSENDFEDLLSNQGFSSRSDKKGPKTIAEMRKQDLAKDTDPLKLKLLDWIEGKERN 1230

Query: 833  IRALLSTMHTVLWAGETKWKPVGMADLVTPEQVKKVYRKAVLVVHPDKATGQPYEQYAKM 892
            IRALLST+HTVLW GE++W PVGMADLV PEQVKK YR+AVL VHPDKA GQPYEQ+AKM
Sbjct: 1231 IRALLSTLHTVLWDGESRWTPVGMADLVAPEQVKKHYRRAVLAVHPDKAAGQPYEQHAKM 1290

Query: 893  IFMELNDAWSEFENQGQKPLY 913
            IFMELNDAWSEFENQG +PL+
Sbjct: 1291 IFMELNDAWSEFENQGSRPLF 1311


>gi|65288071 tensin 3 [Homo sapiens]
          Length = 1445

 Score =  121 bits (304), Expect = 3e-27
 Identities = 95/366 (25%), Positives = 163/366 (44%), Gaps = 40/366 (10%)

Query: 64  LDFTYVTSRIIVMSFPLDNVDIGFRNQVDDIRSFLDSRHLDHYTVYNLSPKSYRTAKFHS 123
           LD TY+T RII +SFP    +  + + + ++   L S+H D+Y V NLS K Y   K + 
Sbjct: 7   LDLTYITERIIAVSFPAGCSEESYLHNLQEVTRMLKSKHGDNYLVLNLSEKRYDLTKLNP 66

Query: 124 RVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDGRAASSILVGAMFIFCN 183
           ++ +  WP   AP L  +  +C+   +WL  N ++V V+HC  G+    +++ +   F N
Sbjct: 67  KIMDVGWPELHAPPLDKMCTICKAQESWLNSNLQHVVVIHCRGGKGRIGVVISSYMHFTN 126

Query: 184 LYSTPGPAI-----RLLYAKRPGIGLSPSHRRYLGYMCDLLADKPYRPHFKPLTIKSITV 238
           + ++   A+     +  Y  +    + PS +RY+ ++  LL+    + +  PL +  + +
Sbjct: 127 VSASADQALDRFAMKKFYDDKVSALMQPSQKRYVQFLSGLLSGS-VKMNASPLFLHFVIL 185

Query: 239 SPIPFFNKQRNGCRPYCDVLIGETKIYSTCTDFERMKEYRVQDGKIFIPLNITVQGDVVV 298
              P F+     CRP+  +      +Y T   +    E   +   +  P  + ++GDV+V
Sbjct: 186 HGTPNFD-TGGVCRPFLKLYQAMQPVY-TSGIYNVGPENPSRICIVIEPAQL-LKGDVMV 242

Query: 299 SMYHLRSTIGSRLQAKVTNTQIFQLQFHTGFIPLDTTVLKFTKPELDACDVPEKYPQLFQ 358
             YH       +     T   IF+LQFHTG +      L F K +LD     +++P   +
Sbjct: 243 KCYH-------KKYRSATRDVIFRLQFHTGAV--QGYGLVFGKEDLDNASKDDRFPDYGK 293

Query: 359 VTLDVELQP------------HDKVIDLTPPWEHYCTKDVNPSILFSSHQE-HQDTLALG 405
           V L     P            H  ++D       Y T D  P I + S++    D   L 
Sbjct: 294 VELVFSATPEKIQGSEHLYNDHGVIVD-------YNTTD--PLIRWDSYENLSADGEVLH 344

Query: 406 GQAPID 411
            Q P+D
Sbjct: 345 TQGPVD 350


>gi|38787970 tensin like C1 domain containing phosphatase isoform 3
           [Homo sapiens]
          Length = 1285

 Score =  120 bits (302), Expect = 4e-27
 Identities = 93/353 (26%), Positives = 166/353 (47%), Gaps = 28/353 (7%)

Query: 63  DLDFTYVTSRIIVMSFPLDNVDIGFRNQVDDIRSFLDSRHLDHYTVYNLSPKSYRTAKFH 122
           DLD TYVT RI+  +FP    +   R  + ++   L S+H D Y ++NLS K +   + +
Sbjct: 6   DLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRHDLTRLN 65

Query: 123 SRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDGRAASSILVGAMFIFC 182
            +V +  WP   AP L  L ++C+ M  WL  +P++V V++C   +    ++V A   + 
Sbjct: 66  PKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSAYMHYS 125

Query: 183 NLYSTPGPAIRLLYAK-----RPGIGLSPSHRRYLGYMCDLLADKPYRPHFKPLTIKSIT 237
            + +    A+  L  +     +    L PS RRY+ Y   LL+    R +  PL +  + 
Sbjct: 126 KISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGS-IRMNSSPLFLHYVL 184

Query: 238 VSPIPFFNKQRNGCRPYCDVLIGETKIYSTCTDFERMKEYRVQDGKIFIPLNITVQGDVV 297
           +  +P F +   G +P+  +      +Y+  +    +     Q   I +   + ++GDV+
Sbjct: 185 IPMLPAF-EPGTGFQPFLKIYQSMQLVYT--SGVYHIAGPGPQQLCISLEPALLLKGDVM 241

Query: 298 VSMYHLRSTIGSRLQAKVTNTQIFQLQFHTGFIPLDTTVLKFTKPELDACDVPEKYPQLF 357
           V+ YH     G R       T +F++QFHT    +    L F K +LD     E++P  F
Sbjct: 242 VTCYHK----GGR---GTDRTLVFRVQFHT--CTIHGPQLTFPKDQLDEAWTDERFP--F 290

Query: 358 QVTLD-VELQPHDKVIDLTPPWEHYCTKDVN---PSILFSSH----QEHQDTL 402
           Q +++ V     +K+   TP  +   + D N   P++ + S+    Q H+D++
Sbjct: 291 QASVEFVFSSSPEKIKGSTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSV 343



 Score = 38.5 bits (88), Expect = 0.029
 Identities = 69/326 (21%), Positives = 104/326 (31%), Gaps = 62/326 (19%)

Query: 468 GNANGDKPHGVKKPSKKQQEPAAPPPPEDVDL-LGLEGSAMSNSFSPP-----AAPPTNS 521
           G   G    G   P      P +PP P+   L   +      + +  P     A P  ++
Sbjct: 689 GEGRGYPSPGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASA 748

Query: 522 ELLSDLFGGGGAAG-------PTQAGQSGVEDVFHPSGPAST-------QSTPRRSATST 567
           E L  +    G +G       P  A  S   ++  PS P  T       +ST R+   S 
Sbjct: 749 ESLEPVSWREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSP 808

Query: 568 SASPTLRVGEGATFDPFGAPSKPSGQDLLGSFLNTSSASSDPFLQPTRSPSPTVHASSTP 627
           +++PT R+  G    P                ++ +     P L     P P   +  +P
Sbjct: 809 TSAPTQRLSPGEALPP----------------VSQAGTGKAPELPSGSGPEPLAPSPVSP 852

Query: 628 AVNIQPDVSGGWDWHAKPGGFGMGSKSAATSPT---GSSHGT-PTHQSKPQTLDPFADLG 683
                P     W     PGG   G+   +  PT   G  H      +  P + D      
Sbjct: 853 --TFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPD------ 904

Query: 684 TLGSSSFASKPTTPTGLGGGFPPLSSPQKASPQPMGGGWQQGGAYNWQQP---------- 733
             GS         P  +    PP SSP  A   P+   +   G      P          
Sbjct: 905 --GSPLTPVPSQMPWLVASPEPPQSSPTPAF--PLAASYDTNGLSQPPLPEKRHLPGPGQ 960

Query: 734 QPKPQPSMPHSSPQNRPNYNVSFSAM 759
           QP P      SSP    +++V+F+ +
Sbjct: 961 QPGPWGPEQASSPARGISHHVTFAPL 986


>gi|38787957 tensin like C1 domain containing phosphatase isoform 2
           [Homo sapiens]
          Length = 1409

 Score =  120 bits (302), Expect = 4e-27
 Identities = 93/353 (26%), Positives = 166/353 (47%), Gaps = 28/353 (7%)

Query: 63  DLDFTYVTSRIIVMSFPLDNVDIGFRNQVDDIRSFLDSRHLDHYTVYNLSPKSYRTAKFH 122
           DLD TYVT RI+  +FP    +   R  + ++   L S+H D Y ++NLS K +   + +
Sbjct: 130 DLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRHDLTRLN 189

Query: 123 SRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDGRAASSILVGAMFIFC 182
            +V +  WP   AP L  L ++C+ M  WL  +P++V V++C   +    ++V A   + 
Sbjct: 190 PKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSAYMHYS 249

Query: 183 NLYSTPGPAIRLLYAK-----RPGIGLSPSHRRYLGYMCDLLADKPYRPHFKPLTIKSIT 237
            + +    A+  L  +     +    L PS RRY+ Y   LL+    R +  PL +  + 
Sbjct: 250 KISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGS-IRMNSSPLFLHYVL 308

Query: 238 VSPIPFFNKQRNGCRPYCDVLIGETKIYSTCTDFERMKEYRVQDGKIFIPLNITVQGDVV 297
           +  +P F +   G +P+  +      +Y+  +    +     Q   I +   + ++GDV+
Sbjct: 309 IPMLPAF-EPGTGFQPFLKIYQSMQLVYT--SGVYHIAGPGPQQLCISLEPALLLKGDVM 365

Query: 298 VSMYHLRSTIGSRLQAKVTNTQIFQLQFHTGFIPLDTTVLKFTKPELDACDVPEKYPQLF 357
           V+ YH     G R       T +F++QFHT    +    L F K +LD     E++P  F
Sbjct: 366 VTCYHK----GGR---GTDRTLVFRVQFHT--CTIHGPQLTFPKDQLDEAWTDERFP--F 414

Query: 358 QVTLD-VELQPHDKVIDLTPPWEHYCTKDVN---PSILFSSH----QEHQDTL 402
           Q +++ V     +K+   TP  +   + D N   P++ + S+    Q H+D++
Sbjct: 415 QASVEFVFSSSPEKIKGSTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSV 467



 Score = 38.5 bits (88), Expect = 0.029
 Identities = 69/326 (21%), Positives = 104/326 (31%), Gaps = 62/326 (19%)

Query: 468  GNANGDKPHGVKKPSKKQQEPAAPPPPEDVDL-LGLEGSAMSNSFSPP-----AAPPTNS 521
            G   G    G   P      P +PP P+   L   +      + +  P     A P  ++
Sbjct: 813  GEGRGYPSPGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASA 872

Query: 522  ELLSDLFGGGGAAG-------PTQAGQSGVEDVFHPSGPAST-------QSTPRRSATST 567
            E L  +    G +G       P  A  S   ++  PS P  T       +ST R+   S 
Sbjct: 873  ESLEPVSWREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSP 932

Query: 568  SASPTLRVGEGATFDPFGAPSKPSGQDLLGSFLNTSSASSDPFLQPTRSPSPTVHASSTP 627
            +++PT R+  G    P                ++ +     P L     P P   +  +P
Sbjct: 933  TSAPTQRLSPGEALPP----------------VSQAGTGKAPELPSGSGPEPLAPSPVSP 976

Query: 628  AVNIQPDVSGGWDWHAKPGGFGMGSKSAATSPT---GSSHGT-PTHQSKPQTLDPFADLG 683
                 P     W     PGG   G+   +  PT   G  H      +  P + D      
Sbjct: 977  --TFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPD------ 1028

Query: 684  TLGSSSFASKPTTPTGLGGGFPPLSSPQKASPQPMGGGWQQGGAYNWQQP---------- 733
              GS         P  +    PP SSP  A   P+   +   G      P          
Sbjct: 1029 --GSPLTPVPSQMPWLVASPEPPQSSPTPAF--PLAASYDTNGLSQPPLPEKRHLPGPGQ 1084

Query: 734  QPKPQPSMPHSSPQNRPNYNVSFSAM 759
            QP P      SSP    +++V+F+ +
Sbjct: 1085 QPGPWGPEQASSPARGISHHVTFAPL 1110


>gi|38787941 tensin like C1 domain containing phosphatase isoform 1
           [Homo sapiens]
          Length = 1419

 Score =  120 bits (302), Expect = 4e-27
 Identities = 93/353 (26%), Positives = 166/353 (47%), Gaps = 28/353 (7%)

Query: 63  DLDFTYVTSRIIVMSFPLDNVDIGFRNQVDDIRSFLDSRHLDHYTVYNLSPKSYRTAKFH 122
           DLD TYVT RI+  +FP    +   R  + ++   L S+H D Y ++NLS K +   + +
Sbjct: 140 DLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRHDLTRLN 199

Query: 123 SRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDGRAASSILVGAMFIFC 182
            +V +  WP   AP L  L ++C+ M  WL  +P++V V++C   +    ++V A   + 
Sbjct: 200 PKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSAYMHYS 259

Query: 183 NLYSTPGPAIRLLYAK-----RPGIGLSPSHRRYLGYMCDLLADKPYRPHFKPLTIKSIT 237
            + +    A+  L  +     +    L PS RRY+ Y   LL+    R +  PL +  + 
Sbjct: 260 KISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGS-IRMNSSPLFLHYVL 318

Query: 238 VSPIPFFNKQRNGCRPYCDVLIGETKIYSTCTDFERMKEYRVQDGKIFIPLNITVQGDVV 297
           +  +P F +   G +P+  +      +Y+  +    +     Q   I +   + ++GDV+
Sbjct: 319 IPMLPAF-EPGTGFQPFLKIYQSMQLVYT--SGVYHIAGPGPQQLCISLEPALLLKGDVM 375

Query: 298 VSMYHLRSTIGSRLQAKVTNTQIFQLQFHTGFIPLDTTVLKFTKPELDACDVPEKYPQLF 357
           V+ YH     G R       T +F++QFHT    +    L F K +LD     E++P  F
Sbjct: 376 VTCYHK----GGR---GTDRTLVFRVQFHT--CTIHGPQLTFPKDQLDEAWTDERFP--F 424

Query: 358 QVTLD-VELQPHDKVIDLTPPWEHYCTKDVN---PSILFSSH----QEHQDTL 402
           Q +++ V     +K+   TP  +   + D N   P++ + S+    Q H+D++
Sbjct: 425 QASVEFVFSSSPEKIKGSTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSV 477



 Score = 38.5 bits (88), Expect = 0.029
 Identities = 69/326 (21%), Positives = 104/326 (31%), Gaps = 62/326 (19%)

Query: 468  GNANGDKPHGVKKPSKKQQEPAAPPPPEDVDL-LGLEGSAMSNSFSPP-----AAPPTNS 521
            G   G    G   P      P +PP P+   L   +      + +  P     A P  ++
Sbjct: 823  GEGRGYPSPGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASA 882

Query: 522  ELLSDLFGGGGAAG-------PTQAGQSGVEDVFHPSGPAST-------QSTPRRSATST 567
            E L  +    G +G       P  A  S   ++  PS P  T       +ST R+   S 
Sbjct: 883  ESLEPVSWREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSP 942

Query: 568  SASPTLRVGEGATFDPFGAPSKPSGQDLLGSFLNTSSASSDPFLQPTRSPSPTVHASSTP 627
            +++PT R+  G    P                ++ +     P L     P P   +  +P
Sbjct: 943  TSAPTQRLSPGEALPP----------------VSQAGTGKAPELPSGSGPEPLAPSPVSP 986

Query: 628  AVNIQPDVSGGWDWHAKPGGFGMGSKSAATSPT---GSSHGT-PTHQSKPQTLDPFADLG 683
                 P     W     PGG   G+   +  PT   G  H      +  P + D      
Sbjct: 987  --TFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPD------ 1038

Query: 684  TLGSSSFASKPTTPTGLGGGFPPLSSPQKASPQPMGGGWQQGGAYNWQQP---------- 733
              GS         P  +    PP SSP  A   P+   +   G      P          
Sbjct: 1039 --GSPLTPVPSQMPWLVASPEPPQSSPTPAF--PLAASYDTNGLSQPPLPEKRHLPGPGQ 1094

Query: 734  QPKPQPSMPHSSPQNRPNYNVSFSAM 759
            QP P      SSP    +++V+F+ +
Sbjct: 1095 QPGPWGPEQASSPARGISHHVTFAPL 1120


>gi|66529407 tensin [Homo sapiens]
          Length = 1735

 Score =  120 bits (300), Expect = 8e-27
 Identities = 86/303 (28%), Positives = 147/303 (48%), Gaps = 20/303 (6%)

Query: 63  DLDFTYVTSRIIVMSFPLDNVDIGFRNQVDDIRSFLDSRHLDHYTVYNLSPKSYRTAKFH 122
           +LD  YVT RII +SFP    +  FR+ + ++   L S+H  +Y ++NLS +     K H
Sbjct: 12  ELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNLSERRPDITKLH 71

Query: 123 SRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDGRAASSILVGAMFIFC 182
           ++V E  WP    P+L  + ++C+ M  WL  +P NV V+H    R    +++ A   + 
Sbjct: 72  AKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGVVIAAYMHYS 131

Query: 183 NLYSTPGPAIRLLYAKR------PGIGLSPSHRRYLGYMCDLLADKPYRPHFKPLTIKSI 236
           N+ ++   A+     KR        IG  PS RRY+ Y   LL+    + + KPL +  +
Sbjct: 132 NISASADQALDRFAMKRFYEDKIVPIG-QPSQRRYVHYFSGLLSGS-IKMNNKPLFLHHV 189

Query: 237 TVSPIPFFNKQRNGCRPYCDVLIGETKIYSTCTDFERMKEYRVQDGKIFIPLNITVQGDV 296
            +  IP F + + GCRP+  +      +Y+  +    +         I I   + ++GD+
Sbjct: 190 IMHGIPNF-ESKGGCRPFLRIYQAMQPVYT--SGIYNIPGDSQTSVCITIEPGLLLKGDI 246

Query: 297 VVSMYHLRSTIGSRLQAKVTNTQIFQLQFHTGFIPLDTTVLKFTKPELDACDVPEKYPQL 356
           ++  YH +    +R         IF++QFHT  I  D  V+ F K +LD     +++P+ 
Sbjct: 247 LLKCYHKKFRSPAR-------DVIFRVQFHTCAIH-DLGVV-FGKEDLDDAFKDDRFPEY 297

Query: 357 FQV 359
            +V
Sbjct: 298 GKV 300


>gi|73765544 phosphatase and tensin homolog [Homo sapiens]
          Length = 403

 Score =  109 bits (273), Expect = 1e-23
 Identities = 77/275 (28%), Positives = 132/275 (48%), Gaps = 21/275 (7%)

Query: 63  DLDFTYVTSRIIVMSFPLDNVDIGFRNQVDDIRSFLDSRHLDHYTVYNL-SPKSYRTAKF 121
           DLD TY+   II M FP + ++  +RN +DD+  FLDS+H +HY +YNL + + Y TAKF
Sbjct: 22  DLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKF 81

Query: 122 HSRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDGRAASSILVGAMFIF 181
           + RV++  +     P L  +   C ++  WL ++  +V  +HC  G+  + +++ A  + 
Sbjct: 82  NCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLH 141

Query: 182 CNLYSTPGPAI----RLLYAKRPGIGLSPSHRRYLGYMCDLLADK-PYRPHFKPLTIKSI 236
              +     A+     +    + G+ + PS RRY+ Y   LL +   YRP    L    +
Sbjct: 142 RGKFLKAQEALDFYGEVRTRDKKGVTI-PSQRRYVYYYSYLLKNHLDYRP--VALLFHKM 198

Query: 237 TVSPIPFFNKQRNGCRPYCDVLIGETKIYSTCTDFERMKEYRVQDGKIFIPLNITVQGDV 296
               IP F+     C P   V   + KIYS+ +   R ++  +       P  + V GD+
Sbjct: 199 MFETIPMFS--GGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMY---FEFPQPLPVCGDI 253

Query: 297 VVSMYHLRSTIGSRLQAKVTNTQIFQLQFHTGFIP 331
            V  +H ++ +       +   ++F    +T FIP
Sbjct: 254 KVEFFHKQNKM-------LKKDKMFHFWVNTFFIP 281


>gi|213972593 TPTE and PTEN homologous inositol lipid phosphatase
           isoform delta [Homo sapiens]
          Length = 411

 Score =  103 bits (256), Expect = 1e-21
 Identities = 57/178 (32%), Positives = 90/178 (50%), Gaps = 11/178 (6%)

Query: 52  VIQSVTSYTKG--DLDFTYVTSRIIVMSFPLDNVDIGFRNQVDDIRSFLDSRHLDHYTVY 109
           V ++   YT+   DLD TYVT RII MSFP       +RN ++++  FLD +H +HY VY
Sbjct: 94  VSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVY 153

Query: 110 NL-SPKSYRTAKFHSRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDGR 168
           NL S ++Y    FH+RVS         P+LH +    + +  W+ Q+ +N+  +HC  G+
Sbjct: 154 NLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGK 213

Query: 169 AASSILVGAMFIFCNLYSTPGPAIRLLYAKRPGIGLS--------PSHRRYLGYMCDL 218
             +  +V A+ I   ++ T   ++     +R     S        PS  RY+GY   +
Sbjct: 214 GRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFAQV 271


>gi|213972591 TPTE and PTEN homologous inositol lipid phosphatase
           isoform gamma [Homo sapiens]
          Length = 522

 Score =  103 bits (256), Expect = 1e-21
 Identities = 57/178 (32%), Positives = 90/178 (50%), Gaps = 11/178 (6%)

Query: 52  VIQSVTSYTKG--DLDFTYVTSRIIVMSFPLDNVDIGFRNQVDDIRSFLDSRHLDHYTVY 109
           V ++   YT+   DLD TYVT RII MSFP       +RN ++++  FLD +H +HY VY
Sbjct: 205 VSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVY 264

Query: 110 NL-SPKSYRTAKFHSRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDGR 168
           NL S ++Y    FH+RVS         P+LH +    + +  W+ Q+ +N+  +HC  G+
Sbjct: 265 NLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGK 324

Query: 169 AASSILVGAMFIFCNLYSTPGPAIRLLYAKRPGIGLS--------PSHRRYLGYMCDL 218
             +  +V A+ I   ++ T   ++     +R     S        PS  RY+GY   +
Sbjct: 325 GRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFAQV 382


>gi|213972589 TPTE and PTEN homologous inositol lipid phosphatase
           isoform alpha [Homo sapiens]
          Length = 445

 Score =  103 bits (256), Expect = 1e-21
 Identities = 57/178 (32%), Positives = 90/178 (50%), Gaps = 11/178 (6%)

Query: 52  VIQSVTSYTKG--DLDFTYVTSRIIVMSFPLDNVDIGFRNQVDDIRSFLDSRHLDHYTVY 109
           V ++   YT+   DLD TYVT RII MSFP       +RN ++++  FLD +H +HY VY
Sbjct: 128 VSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVY 187

Query: 110 NL-SPKSYRTAKFHSRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDGR 168
           NL S ++Y    FH+RVS         P+LH +    + +  W+ Q+ +N+  +HC  G+
Sbjct: 188 NLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGK 247

Query: 169 AASSILVGAMFIFCNLYSTPGPAIRLLYAKRPGIGLS--------PSHRRYLGYMCDL 218
             +  +V A+ I   ++ T   ++     +R     S        PS  RY+GY   +
Sbjct: 248 GRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFAQV 305


>gi|40549435 transmembrane phosphatase with tensin homology isoform
           gamma [Homo sapiens]
          Length = 513

 Score = 97.4 bits (241), Expect = 5e-20
 Identities = 57/180 (31%), Positives = 89/180 (49%), Gaps = 13/180 (7%)

Query: 51  RVIQSVTSYTKG--DLDFTYVTSRIIVMSFPLDNVDIGFRNQVDDIRSFLDSRHLDHYTV 108
           RV ++   YT+   DLD TYVT RII MSFP       +RN + ++  FLD +H +HY V
Sbjct: 184 RVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRV 243

Query: 109 YNL-SPKSYRTAKFHSRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDG 167
           YNL S ++Y    FH+RV          P+LH +    + +  W+ Q+ +N+  +HC  G
Sbjct: 244 YNLCSERAYDPKHFHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGG 303

Query: 168 RAASSILVGAMFIFCNLYSTPGPAIRLLYAKR---------PGIGLSPSHRRYLGYMCDL 218
              +  +V A  I   + ST   ++     +R          G+  +PS +RY+ Y   +
Sbjct: 304 TDRTGTMVCAFLIASEICSTAKESLYYFGERRTDKTHSEKFQGVE-TPSQKRYVAYFAQV 362


>gi|40549433 transmembrane phosphatase with tensin homology isoform
           beta [Homo sapiens]
          Length = 533

 Score = 97.4 bits (241), Expect = 5e-20
 Identities = 57/180 (31%), Positives = 89/180 (49%), Gaps = 13/180 (7%)

Query: 51  RVIQSVTSYTKG--DLDFTYVTSRIIVMSFPLDNVDIGFRNQVDDIRSFLDSRHLDHYTV 108
           RV ++   YT+   DLD TYVT RII MSFP       +RN + ++  FLD +H +HY V
Sbjct: 204 RVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRV 263

Query: 109 YNL-SPKSYRTAKFHSRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDG 167
           YNL S ++Y    FH+RV          P+LH +    + +  W+ Q+ +N+  +HC  G
Sbjct: 264 YNLCSERAYDPKHFHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGG 323

Query: 168 RAASSILVGAMFIFCNLYSTPGPAIRLLYAKR---------PGIGLSPSHRRYLGYMCDL 218
              +  +V A  I   + ST   ++     +R          G+  +PS +RY+ Y   +
Sbjct: 324 TDRTGTMVCAFLIASEICSTAKESLYYFGERRTDKTHSEKFQGVE-TPSQKRYVAYFAQV 382


>gi|109689707 transmembrane phosphatase with tensin homology isoform
           alpha [Homo sapiens]
          Length = 551

 Score = 97.4 bits (241), Expect = 5e-20
 Identities = 57/180 (31%), Positives = 89/180 (49%), Gaps = 13/180 (7%)

Query: 51  RVIQSVTSYTKG--DLDFTYVTSRIIVMSFPLDNVDIGFRNQVDDIRSFLDSRHLDHYTV 108
           RV ++   YT+   DLD TYVT RII MSFP       +RN + ++  FLD +H +HY V
Sbjct: 222 RVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRV 281

Query: 109 YNL-SPKSYRTAKFHSRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDG 167
           YNL S ++Y    FH+RV          P+LH +    + +  W+ Q+ +N+  +HC  G
Sbjct: 282 YNLCSERAYDPKHFHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGG 341

Query: 168 RAASSILVGAMFIFCNLYSTPGPAIRLLYAKR---------PGIGLSPSHRRYLGYMCDL 218
              +  +V A  I   + ST   ++     +R          G+  +PS +RY+ Y   +
Sbjct: 342 TDRTGTMVCAFLIASEICSTAKESLYYFGERRTDKTHSEKFQGVE-TPSQKRYVAYFAQV 400


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 57.8 bits (138), Expect = 5e-08
 Identities = 91/364 (25%), Positives = 124/364 (34%), Gaps = 70/364 (19%)

Query: 437  EKSFCEEDHAALVNQESEQSDDELLTLSSPHGNANGD-----KPHGVKKPSKKQQEPA-- 489
            E SF  E+  +    +   +     T  SP G           P GV  P K+   P+  
Sbjct: 832  EASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVV 891

Query: 490  ---------APPPPEDVDLLGLEGSAMSN------------SFSPPAAPPTNSELLSDLF 528
                     A P P+    L +  S+               S SP  AP   +       
Sbjct: 892  NLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPK 951

Query: 529  GGGGAAGPTQAGQSGVEDVFHPSGPASTQSTPRRSATSTSASPTLRVGEGATFDPFGAPS 588
            GG     P  A          P G  +T S P+ + T  +A+P    G  AT  P GAP+
Sbjct: 952  GGPATPSPKWAPTPPAATPPSPKGGPATPS-PKGAPTPPAATPPSPKGGPATPSPKGAPT 1010

Query: 589  -------KPSGQDLLGSF---LNTSSASSDPFLQPTRSPSPT---VHASSTPAVNIQPDV 635
                    P G      F    +T  A++ P   P  SP+ T     A +TPA  + P  
Sbjct: 1011 PPAVTPPSPKGSPAATPFPKGASTPPAATPP--SPKGSPAATPLPKGAPTTPAATL-PSP 1067

Query: 636  SGGWDWHAKPGGFGMGSKSAATSPT---GSSHGTPTHQSKPQTLDPFADLGTLGSSSFAS 692
             GG    A P   G  +  AAT P+   G +  +P     P    P +  G L +     
Sbjct: 1068 KGG---PATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKG 1124

Query: 693  KPTTPTGL------GGGFPP----LSSPQKASPQPMGGGWQQGGAYNWQQPQPKPQPSMP 742
             PTTP         G   PP     ++P    P P GG            P PK  P+ P
Sbjct: 1125 APTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG---------LATPPPKGAPTTP 1175

Query: 743  HSSP 746
             ++P
Sbjct: 1176 AATP 1179



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 82/294 (27%), Positives = 117/294 (39%), Gaps = 48/294 (16%)

Query: 462  TLSSPHGNANGDKPHGVKKPSKKQQEPAAPPPPEDVDLLGLEGSAMSNSFSPPAAPPTNS 521
            T  SP G      P G           A PP P+     GL   +   + + PAA P + 
Sbjct: 1155 TPPSPKGGLATPPPKGAPTTPA-----ATPPSPKG----GLATPSPKGAPTTPAATPPSP 1205

Query: 522  ELLSDLFGGGGAAGPTQAGQSGVEDVFHPS--GPASTQSTPRRSATSTSASPTLRVGEGA 579
            +        GG A P+  G         PS  G  +T S P+ + T+ +A+P    G  A
Sbjct: 1206 K--------GGLATPSPKGAPTTPAATPPSPKGGLATPS-PKGAPTTPAATPPSPKGGPA 1256

Query: 580  TFDPFGAPSKPSGQDLLGSFLNTSSASSDPFLQPTRSPSPTVHASSTPAVNIQPDVSGGW 639
            T  P GAP+ P              A++ P L+   + +P    +  PAV   P   GG 
Sbjct: 1257 TPPPKGAPTPP--------------AATPPSLKGGLA-TPPHKGAPNPAVVTPPSPKGG- 1300

Query: 640  DWHAKPGGFGMGSKSAATSPTGSSHGTPTHQS--KPQTLDPFADLG--TLGSSSFASK-- 693
               + P G      +   SP GS  GTP  +    P  + P +  G  TL +++ +SK  
Sbjct: 1301 PATSPPKGAPTPPAATPPSPKGSP-GTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGG 1359

Query: 694  PTTPTGLGGGFPPLSSP-QKASPQPMGGGWQQGGAYNWQQPQPKPQPSMPHSSP 746
            PTTP+   G  PP ++P  K  P       ++G A     P PK  P+ P   P
Sbjct: 1360 PTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAI----PSPKGDPTSPAVIP 1409



 Score = 37.4 bits (85), Expect = 0.064
 Identities = 70/261 (26%), Positives = 90/261 (34%), Gaps = 46/261 (17%)

Query: 481  PSKKQQEPAAPPPPEDVDLLGLEGSAMSNSFSPPAAPPTNSELLSDLFGGGGAAGPTQAG 540
            P K    PA   PP      G   S    + +PPAA P + +      G  G   P  A 
Sbjct: 1282 PHKGAPNPAVVTPPSPKG--GPATSPPKGAPTPPAATPPSPK------GSPGTPPPKGA- 1332

Query: 541  QSGVEDVFHPSGPASTQSTPRRSATSTSASPTLRVG-------EGATFDPFGAPSKPSGQ 593
                     P+ PA T  +P+ + T  + +P+ + G       EG T  P   PS   G 
Sbjct: 1333 ---------PTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPT-PPAATPSHKGGP 1382

Query: 594  DLLGSFLNTSSASSDPFLQPTRSPSPTVHASSTPAVNIQPDVSGGWDWHAK-----PGGF 648
             +         A   P   PT   SP V   S       P    G    +K     P   
Sbjct: 1383 AMTPPSPKRGPAIPSPKGDPT---SPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVT 1439

Query: 649  GMGSKSA-ATSP------TGSSHGTPTHQS--KPQTLDPFADLGTLGSSSFASKPTTPTG 699
             +  K A ATS       T SS G PT  +   P   +P A      SSS    P TP  
Sbjct: 1440 PVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAP 1499

Query: 700  LGGGFPPL---SSPQKASPQP 717
            +G    P    SSP++    P
Sbjct: 1500 MGAPTLPAVIPSSPKEVPATP 1520



 Score = 34.3 bits (77), Expect = 0.54
 Identities = 67/299 (22%), Positives = 96/299 (32%), Gaps = 63/299 (21%)

Query: 481 PSKKQQEPAAPPPPEDVDLLG--LEGSAMSNSFSPPAAPPTNSELLSDLFGGGGAAGPTQ 538
           P+  +  P AP P      L   +    +  S   P+ PP                  T 
Sbjct: 702 PTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAG----------------TP 745

Query: 539 AGQSGVEDVFHPSGPASTQSTPRRSATSTSASPTLRVGEGATFDPFGAPSKPSGQDLLGS 598
            G   V+ + H S  A   S+P+   T  S +      +G       +PS P G  +   
Sbjct: 746 PGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPS-PLGVSVSPQ 804

Query: 599 F----LNTSSASSDPFLQPTRSPSPTVHASSTP--AVNIQPDVSGGWDWHA--KPGGFGM 650
                    SA  D  +    SP   V AS  P  +++ Q         H+   P   G 
Sbjct: 805 TKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGA 864

Query: 651 GSKSAAT-------------SPTGSSHGTPTHQSKPQTLDPFADLGTLGSSSFASK---- 693
            + SA T             +PT S    P  +  P T  P        +SS   K    
Sbjct: 865 PTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARAT 924

Query: 694 ------PTTPTGLGGGFPPLSSPQKASPQPMGGGWQQGGAYNWQQPQPKPQPSMPHSSP 746
                 P +P+  G   PP ++P    P P GG            P PK  P+ P ++P
Sbjct: 925 PAPKGIPASPSPKGAPTPPAATP----PSPKGGP---------ATPSPKWAPTPPAATP 970


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 80/328 (24%), Positives = 100/328 (30%), Gaps = 59/328 (17%)

Query: 449 VNQESEQSDDELLTLSSPHGNA--NGDKPHGVKKPSKKQQEP---------AAPPPPEDV 497
           +N++  Q +   L   +P G     G+KP G   P  K Q P           PPPP   
Sbjct: 19  LNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKP 78

Query: 498 DLLGLEGSAMSNSFSPPAAP----PTNSELLSDLFGGGGAAGPTQAGQSGVEDVFHPSGP 553
                +G        PP  P    P   +  S     G   GP   G  G +    P  P
Sbjct: 79  QGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG--GNQPQGPPPPP 136

Query: 554 ASTQSTPRRSATSTSASPTLRVGEGATFDPFGAPSKPSGQDLLGSFLNTSSASSDPFLQP 613
              Q  P +        P               P KP G    G   N S +S  P   P
Sbjct: 137 GKPQGPPPQGGNKPQGPPP--------------PGKPQGPPPQGD--NKSRSSRSP---P 177

Query: 614 TRSPSPTVHASSTPAVNIQPDVSGGWDWHAKPGGFGMGSKSAATSPTGSSHGTPTHQSKP 673
            +   P     + P     P    G      P G   G+K     P G   G P      
Sbjct: 178 GKPQGPPPQGGNQPQ---GPPPPPGKPQGPPPQG---GNKPQGPPPPGKPQGPP------ 225

Query: 674 QTLDPFADLGTLGSSSFASKPTTPTGLGGGFPPLSSPQKASPQPMGGGWQQGGAYNWQQP 733
               P  D  +  + S   KP  P   GG  P    P    PQ   G   QGG     +P
Sbjct: 226 ----PQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQ---GPPPQGG----NKP 274

Query: 734 QPKPQPSMPHSSPQNRPNYNVSFSAMPG 761
           Q  P P  P   P    + + S  + PG
Sbjct: 275 QGPPPPGKPQGPPPQGGSKSRSSRSPPG 302



 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 76/302 (25%), Positives = 91/302 (30%), Gaps = 37/302 (12%)

Query: 466 PHGNANGDKPHGVKKPSKKQQ--EPAAPPPPEDVDLLGLEGSAMSNSFSPPAAPPTNSEL 523
           P G   G  P G K  S +    +P  PPP         +G        PP   P     
Sbjct: 94  PPGKPQGPPPQGDKSRSPRSPPGKPQGPPP---------QGGNQPQGPPPPPGKPQGPPP 144

Query: 524 LSDLFGGGGAAGPTQAGQSGVEDVFHPSGPASTQSTPRRSATSTSASPTLRVGEGATFD- 582
                GG    GP   G+        P GP        RS+ S    P     +G     
Sbjct: 145 Q----GGNKPQGPPPPGK--------PQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQ 192

Query: 583 -PFGAPSKPSGQDLLGSFLNTSSAS-SDPFLQPTRSPSPTVHASSTPAVNIQPDVSGGWD 640
            P   P KP G    G            P   P +  + +  A S P     P   GG  
Sbjct: 193 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQ 252

Query: 641 WHAKPGGFGMGSKSAATSPTGSSHGT-PTHQSKPQTLDPFADLGTLGSSSFASKPTTPTG 699
               P   G   K     P G +    P    KPQ   P     +  S S   KP  P  
Sbjct: 253 PQGPPPPPG---KPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPP 309

Query: 700 LGGGFPPLSSPQKASPQPMGGGWQQGGAYNWQQPQPKPQPSMPHSSPQNRPNYNVSFSAM 759
            GG  P    P    PQ   G   QGG     +PQ  P P  P   P    + + S  + 
Sbjct: 310 QGGNQPQGPPPPPGKPQ---GPPPQGG----NKPQGPPPPGKPQGPPPQGGSKSRSARSP 362

Query: 760 PG 761
           PG
Sbjct: 363 PG 364



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 78/303 (25%), Positives = 95/303 (31%), Gaps = 61/303 (20%)

Query: 455 QSDDELLTLSSPHGNANGDKPHGVKKPSKKQQEPAAP--PPPEDVDLLGLEGSAMSNSFS 512
           Q D++  +  SP G   G  P G  +P      P  P  PPP+     G +         
Sbjct: 165 QGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG----GNKPQGPPPPGK 220

Query: 513 PPAAPPT-NSELLSDLFGGGGAAGPTQAGQSGVEDVFHPSGPASTQSTPRRSATSTSASP 571
           P   PP  +++  S     G   GP   G  G +    P  P   Q  P +        P
Sbjct: 221 PQGPPPQGDNKSQSARSPPGKPQGPPPQG--GNQPQGPPPPPGKPQGPPPQGGNKPQGPP 278

Query: 572 TLRVGEGATFDPFGAPSKPSGQDLLGSFLNTSSASSDPFLQPTRSPSPTVHASSTPAVNI 631
                          P KP G    G   + SS S      P +   P     + P    
Sbjct: 279 P--------------PGKPQGPPPQGGSKSRSSRSP-----PGKPQGPPPQGGNQPQ--- 316

Query: 632 QPDVSGGWDWHAKPGGFGMGSKSAATSPTGSSHGTPTHQSKPQTLDPFADLGTLGSSSFA 691
            P    G      P G   G+K     P G   G P     PQ        G   S S  
Sbjct: 317 GPPPPPGKPQGPPPQG---GNKPQGPPPPGKPQGPP-----PQ--------GGSKSRSAR 360

Query: 692 SKPTTPTGLGGGFPPLSSPQKASPQPMGGGWQQGGAYNWQQPQPKP--QPSMPHSSPQ-N 748
           S P  P G          PQ+    P G     GG  N QQPQ  P  QP  P   PQ  
Sbjct: 361 SPPGKPQG---------PPQQEGNNPQGPPPPAGG--NPQQPQAPPAGQPQGPPRPPQGG 409

Query: 749 RPN 751
           RP+
Sbjct: 410 RPS 412


>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1
           [Homo sapiens]
          Length = 2231

 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 82/336 (24%), Positives = 114/336 (33%), Gaps = 49/336 (14%)

Query: 453 SEQSDDELLTLSSPHGNANGDKPHGVKKPSKKQQEPAAPPPPEDVDLLGLEG---SAMSN 509
           S+ S  + + +  P     G  PH   + S      +  PP      +G++G    AM+ 
Sbjct: 455 SQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAG 514

Query: 510 SFSPPAAPPTNSELLSDLFGGGGAAGPTQAGQSGV--EDVFHPSGPASTQSTPRRSATST 567
              P    P         +G  G +G  Q GQ     +    P  P   Q  P +S    
Sbjct: 515 MQYPQQQMPPQ-------YGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRY 567

Query: 568 SASPTL-RVGEGATFDPFGAPSKPSGQDLLGSFLNTSSASSDPFLQPTRSPSPT-VHASS 625
                + + G G    P  AP KP+ +DL  + +     SS P L  +    PT   A+ 
Sbjct: 568 QPQQDMSQEGYGTRSQPPLAPGKPNHEDL--NLIQQERPSSLPDLSGSIDDLPTGTEATL 625

Query: 626 TPAVNIQPDVSGGWDWHAKPGGFGMGSKSAATSPTGSSHGTPTHQSKPQTLDPFADLGTL 685
           + AV+     S   D             + A SP  S H +P   S P    P      +
Sbjct: 626 SSAVSASGSTSSQGD-----------QSNPAQSPF-SPHASPHLSSIPGGPSPSPVGSPV 673

Query: 686 GSSSFASKPTTPTGLGGGFPPLSSPQKAS-----------PQPMGGGWQQGGAYNWQQPQ 734
           GS+   S P +P  + G   P   P   S           P P   G+  G   N Q  Q
Sbjct: 674 GSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQ 733

Query: 735 PKPQPSMPHSSPQNRPNYNVSFSAMPGGQNERGKGS 770
             PQ + P  SP             PGGQ   G  S
Sbjct: 734 YGPQQTGPSMSPH----------PSPGGQMHAGISS 759



 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 67/258 (25%), Positives = 92/258 (35%), Gaps = 66/258 (25%)

Query: 529 GGGGAAGPTQAGQSGVEDVF--------HPSGPASTQSTPRRSATSTSASPTLRVGEGAT 580
           GGGGAA  ++A        F        HPSG     +TP  +   TS SP +R   G +
Sbjct: 325 GGGGAASLSKAAAGSAAGGFQRFAGQNQHPSG-----ATPTLNQLLTSPSPMMR-SYGGS 378

Query: 581 FDPFGAPSKP------------------SGQDL-----LGSFLNTSSASSDPFLQPTRSP 617
           +  + +PS P                   GQ       LG  +    A++ P     +  
Sbjct: 379 YPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQR 438

Query: 618 SPTVHASSTPAVNIQPDVSGGWDWHA--KPGGFGMGSKSAA----TSP-TGSSHGTPTHQ 670
           S    +  TP   +        D     +P  +GMGS   +    +SP  G S+G P  Q
Sbjct: 439 SHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQ 498

Query: 671 SKPQTLDPFADLGTLGSSSFASKPTTPTGLGG-GFPPLSSPQKASPQPMGGGWQQGGAYN 729
             P        +G  G         TP  + G  +P    P +   Q + G  QQG    
Sbjct: 499 RYP--------IGIQGR--------TPGAMAGMQYPQQQMPPQYGQQGVSGYCQQG---- 538

Query: 730 WQQPQPKPQPSMPHSSPQ 747
            QQP    QP  PH  PQ
Sbjct: 539 -QQPYYSQQPQPPHLPPQ 555



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 60/217 (27%), Positives = 83/217 (38%), Gaps = 40/217 (18%)

Query: 529 GGGGAAGPTQAGQSGVEDVFHPSGPASTQSTPRRSATSTSASPTLRVGEGATFDPFGAPS 588
           GGG   GP   G + +      S     Q    ++   + A+PTL            +PS
Sbjct: 317 GGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLN-------QLLTSPS 369

Query: 589 KPSGQDLLGSFLNTSSASSDPFLQPTRSPSPTVHASSTPAVNIQPDVSGGWDWHAKPG-G 647
            P  +   GS+   SS S+ P       P P+   S   A       +GG    A  G G
Sbjct: 370 -PMMRSYGGSYPEYSSPSAPP-------PPPSQPQSQAAAAGA---AAGGQQAAAGMGLG 418

Query: 648 FGMGSKSAATSPTGSSHGTPTHQS-KPQTLDPFADLGTLGSSSFASKPTTPTGL------ 700
             MG++ AA SP  ++    +H +  P T  P     T+G S     P  P  +      
Sbjct: 419 KDMGAQYAAASPAWAAAQQRSHPAMSPGTPGP-----TMGRSQ--GSPMDPMVMKRPQLY 471

Query: 701 GGGFPPLSSPQKASPQPMGGGWQQGGAYNWQQPQPKP 737
           G G  P S PQ++SP P       GG+Y    PQ  P
Sbjct: 472 GMGSNPHSQPQQSSPYP-------GGSYGPPGPQRYP 501



 Score = 39.3 bits (90), Expect = 0.017
 Identities = 76/320 (23%), Positives = 108/320 (33%), Gaps = 75/320 (23%)

Query: 484 KQQEPAAPPPP--EDVDLLGLEGSAMSNSFSPPAAPPTNSELLSDLFGGGGAAGPTQAGQ 541
           + Q P AP  P  ED++L+  E          P++ P  S  + DL  G      T+A  
Sbjct: 581 RSQPPLAPGKPNHEDLNLIQQER---------PSSLPDLSGSIDDLPTG------TEATL 625

Query: 542 SGVEDVFHPSGPASTQSTPRRSATSTSASPTLR-VGEGATFDPFGAP-------SKP-SG 592
           S        +     QS P +S  S  ASP L  +  G +  P G+P       S P S 
Sbjct: 626 SSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISP 685

Query: 593 QDLLGSFL------NTSSASSDPFLQPT-------------RSPSPTVHASSTPAVNIQP 633
             + GS +      + S +SS P L  +             R+P    +       ++ P
Sbjct: 686 ASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSP 745

Query: 634 DVSGGWDWHAKPGGFGMGSKSAATSPTGSSHGTPTHQSKPQTLDPFADLGTLGSSSFASK 693
             S G   HA    F   + S    P  S +G   + S+P              S   S 
Sbjct: 746 HPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAY-----------SGVPSA 794

Query: 694 PTTPTGLGGGFPPLSSPQKASP-QPMGGGWQQGGAYNWQQPQPKPQPSMPHSSPQNRP-- 750
             +  G G G    +      P QP G                 P   MP +  QNRP  
Sbjct: 795 SYSGPGPGMGISANNQMHGQGPSQPCGA---------------VPLGRMPSAGMQNRPFP 839

Query: 751 -NYNVSFSAMPGGQNERGKG 769
            N +    + PG   + G G
Sbjct: 840 GNMSSMTPSSPGMSQQGGPG 859



 Score = 31.2 bits (69), Expect = 4.6
 Identities = 86/388 (22%), Positives = 125/388 (32%), Gaps = 62/388 (15%)

Query: 412  IPPDNPRHYGQSGFFASLCWQDQKSEKSFCE--EDHAALVNQESEQSDDELLTLSSPHGN 469
            +PP  P    +S    +L       E+ F    + +  +     +Q+   +    SPH +
Sbjct: 693  MPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSM----SPHPS 748

Query: 470  ANGDKPHGVKKPSKKQQEPAAPPPPEDVDLLGLEGSAMSNSFSPPAAPPTNSELLSDLFG 529
              G    G+   S  QQ  ++      +   G +G    N   PPA     S   S    
Sbjct: 749  PGGQMHAGI---SSFQQSNSSGTYGPQMSQYGPQG----NYSRPPAYSGVPSASYSGPGP 801

Query: 530  GGGAAGPTQAGQSGVEDVFH-------PSGPASTQSTPRRSATSTSASPTLRVGEGATFD 582
            G G +   Q    G             PS     +  P   ++ T +SP +    G    
Sbjct: 802  GMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMG 861

Query: 583  P---------------FGAPSKPSGQDLLGSF--LNTSS--ASSDPFLQPTRSPSPTVHA 623
            P                   +  S Q   GSF  +N S   ASS P+ QP  + S  ++ 
Sbjct: 862  PPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNT 921

Query: 624  SSTPAVNIQPDVSGGWDWHAKPGGFGMGSKSAATSP-----TGSSHGTPTHQSKPQTLDP 678
             + P       V+      A  G   M S   +  P      G   GTP  +SK +  D 
Sbjct: 922  QAPPYSMAPAMVNSS---AASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSK--DS 976

Query: 679  FADLGTLGSSSFASKPTTPTGLGGGFPPLSSPQKASPQPMGGGWQQGGAYNWQQPQPKPQ 738
            +       SS   S+P TP  L    P   SP  AS     G        +   P     
Sbjct: 977  Y-------SSQGISQPPTPGNL--PVPSPMSPSSASISSFHGDESD----SISSPGWPKT 1023

Query: 739  PSMPHSSPQNRPNYNVSFSAMPGGQNER 766
            PS P SS        ++     G + ER
Sbjct: 1024 PSSPKSSSSTTTGEKITKVYELGNEPER 1051



 Score = 31.2 bits (69), Expect = 4.6
 Identities = 32/139 (23%), Positives = 53/139 (38%), Gaps = 6/139 (4%)

Query: 484  KQQEPAAPPPPEDVDLLGLEGSAMSNSFSPPAAPPTNSELLSDLFGGGGAAGPTQAGQSG 543
            K+Q    PP P +   L    +  S   +  A  P + +  +      G   P Q G+S 
Sbjct: 1155 KKQPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSS 1214

Query: 544  VEDVFHPSGPASTQSTPRRSATSTSASPTLRVGEGATF-DPFGAPSKPSGQDLLGSFLNT 602
               V  P    S  S P+R+    S +P     +G +  D  G       +D  G  +  
Sbjct: 1215 TISVHDPFSDVSDSSFPKRN----SMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGG-MRK 1269

Query: 603  SSASSDPFLQPTRSPSPTV 621
               SS+PF+   + P+ ++
Sbjct: 1270 VPGSSEPFMTQGQMPNSSM 1288


>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3
           [Homo sapiens]
          Length = 2178

 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 82/336 (24%), Positives = 114/336 (33%), Gaps = 49/336 (14%)

Query: 453 SEQSDDELLTLSSPHGNANGDKPHGVKKPSKKQQEPAAPPPPEDVDLLGLEG---SAMSN 509
           S+ S  + + +  P     G  PH   + S      +  PP      +G++G    AM+ 
Sbjct: 455 SQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAG 514

Query: 510 SFSPPAAPPTNSELLSDLFGGGGAAGPTQAGQSGV--EDVFHPSGPASTQSTPRRSATST 567
              P    P         +G  G +G  Q GQ     +    P  P   Q  P +S    
Sbjct: 515 MQYPQQQMPPQ-------YGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRY 567

Query: 568 SASPTL-RVGEGATFDPFGAPSKPSGQDLLGSFLNTSSASSDPFLQPTRSPSPT-VHASS 625
                + + G G    P  AP KP+ +DL  + +     SS P L  +    PT   A+ 
Sbjct: 568 QPQQDMSQEGYGTRSQPPLAPGKPNHEDL--NLIQQERPSSLPDLSGSIDDLPTGTEATL 625

Query: 626 TPAVNIQPDVSGGWDWHAKPGGFGMGSKSAATSPTGSSHGTPTHQSKPQTLDPFADLGTL 685
           + AV+     S   D             + A SP  S H +P   S P    P      +
Sbjct: 626 SSAVSASGSTSSQGD-----------QSNPAQSPF-SPHASPHLSSIPGGPSPSPVGSPV 673

Query: 686 GSSSFASKPTTPTGLGGGFPPLSSPQKAS-----------PQPMGGGWQQGGAYNWQQPQ 734
           GS+   S P +P  + G   P   P   S           P P   G+  G   N Q  Q
Sbjct: 674 GSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQ 733

Query: 735 PKPQPSMPHSSPQNRPNYNVSFSAMPGGQNERGKGS 770
             PQ + P  SP             PGGQ   G  S
Sbjct: 734 YGPQQTGPSMSPH----------PSPGGQMHAGISS 759



 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 67/258 (25%), Positives = 92/258 (35%), Gaps = 66/258 (25%)

Query: 529 GGGGAAGPTQAGQSGVEDVF--------HPSGPASTQSTPRRSATSTSASPTLRVGEGAT 580
           GGGGAA  ++A        F        HPSG     +TP  +   TS SP +R   G +
Sbjct: 325 GGGGAASLSKAAAGSAAGGFQRFAGQNQHPSG-----ATPTLNQLLTSPSPMMR-SYGGS 378

Query: 581 FDPFGAPSKP------------------SGQDL-----LGSFLNTSSASSDPFLQPTRSP 617
           +  + +PS P                   GQ       LG  +    A++ P     +  
Sbjct: 379 YPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQR 438

Query: 618 SPTVHASSTPAVNIQPDVSGGWDWHA--KPGGFGMGSKSAA----TSP-TGSSHGTPTHQ 670
           S    +  TP   +        D     +P  +GMGS   +    +SP  G S+G P  Q
Sbjct: 439 SHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQ 498

Query: 671 SKPQTLDPFADLGTLGSSSFASKPTTPTGLGG-GFPPLSSPQKASPQPMGGGWQQGGAYN 729
             P        +G  G         TP  + G  +P    P +   Q + G  QQG    
Sbjct: 499 RYP--------IGIQGR--------TPGAMAGMQYPQQQMPPQYGQQGVSGYCQQG---- 538

Query: 730 WQQPQPKPQPSMPHSSPQ 747
            QQP    QP  PH  PQ
Sbjct: 539 -QQPYYSQQPQPPHLPPQ 555



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 60/217 (27%), Positives = 83/217 (38%), Gaps = 40/217 (18%)

Query: 529 GGGGAAGPTQAGQSGVEDVFHPSGPASTQSTPRRSATSTSASPTLRVGEGATFDPFGAPS 588
           GGG   GP   G + +      S     Q    ++   + A+PTL            +PS
Sbjct: 317 GGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLN-------QLLTSPS 369

Query: 589 KPSGQDLLGSFLNTSSASSDPFLQPTRSPSPTVHASSTPAVNIQPDVSGGWDWHAKPG-G 647
            P  +   GS+   SS S+ P       P P+   S   A       +GG    A  G G
Sbjct: 370 -PMMRSYGGSYPEYSSPSAPP-------PPPSQPQSQAAAAGA---AAGGQQAAAGMGLG 418

Query: 648 FGMGSKSAATSPTGSSHGTPTHQS-KPQTLDPFADLGTLGSSSFASKPTTPTGL------ 700
             MG++ AA SP  ++    +H +  P T  P     T+G S     P  P  +      
Sbjct: 419 KDMGAQYAAASPAWAAAQQRSHPAMSPGTPGP-----TMGRSQ--GSPMDPMVMKRPQLY 471

Query: 701 GGGFPPLSSPQKASPQPMGGGWQQGGAYNWQQPQPKP 737
           G G  P S PQ++SP P       GG+Y    PQ  P
Sbjct: 472 GMGSNPHSQPQQSSPYP-------GGSYGPPGPQRYP 501



 Score = 39.3 bits (90), Expect = 0.017
 Identities = 76/320 (23%), Positives = 108/320 (33%), Gaps = 75/320 (23%)

Query: 484 KQQEPAAPPPP--EDVDLLGLEGSAMSNSFSPPAAPPTNSELLSDLFGGGGAAGPTQAGQ 541
           + Q P AP  P  ED++L+  E          P++ P  S  + DL  G      T+A  
Sbjct: 581 RSQPPLAPGKPNHEDLNLIQQER---------PSSLPDLSGSIDDLPTG------TEATL 625

Query: 542 SGVEDVFHPSGPASTQSTPRRSATSTSASPTLR-VGEGATFDPFGAP-------SKP-SG 592
           S        +     QS P +S  S  ASP L  +  G +  P G+P       S P S 
Sbjct: 626 SSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISP 685

Query: 593 QDLLGSFL------NTSSASSDPFLQPT-------------RSPSPTVHASSTPAVNIQP 633
             + GS +      + S +SS P L  +             R+P    +       ++ P
Sbjct: 686 ASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSP 745

Query: 634 DVSGGWDWHAKPGGFGMGSKSAATSPTGSSHGTPTHQSKPQTLDPFADLGTLGSSSFASK 693
             S G   HA    F   + S    P  S +G   + S+P              S   S 
Sbjct: 746 HPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAY-----------SGVPSA 794

Query: 694 PTTPTGLGGGFPPLSSPQKASP-QPMGGGWQQGGAYNWQQPQPKPQPSMPHSSPQNRP-- 750
             +  G G G    +      P QP G                 P   MP +  QNRP  
Sbjct: 795 SYSGPGPGMGISANNQMHGQGPSQPCGA---------------VPLGRMPSAGMQNRPFP 839

Query: 751 -NYNVSFSAMPGGQNERGKG 769
            N +    + PG   + G G
Sbjct: 840 GNMSSMTPSSPGMSQQGGPG 859



 Score = 31.2 bits (69), Expect = 4.6
 Identities = 32/139 (23%), Positives = 53/139 (38%), Gaps = 6/139 (4%)

Query: 484  KQQEPAAPPPPEDVDLLGLEGSAMSNSFSPPAAPPTNSELLSDLFGGGGAAGPTQAGQSG 543
            K+Q    PP P +   L    +  S   +  A  P + +  +      G   P Q G+S 
Sbjct: 1102 KKQPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSS 1161

Query: 544  VEDVFHPSGPASTQSTPRRSATSTSASPTLRVGEGATF-DPFGAPSKPSGQDLLGSFLNT 602
               V  P    S  S P+R+    S +P     +G +  D  G       +D  G  +  
Sbjct: 1162 TISVHDPFSDVSDSSFPKRN----SMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGG-MRK 1216

Query: 603  SSASSDPFLQPTRSPSPTV 621
               SS+PF+   + P+ ++
Sbjct: 1217 VPGSSEPFMTQGQMPNSSM 1235


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 53.9 bits (128), Expect = 7e-07
 Identities = 76/323 (23%), Positives = 95/323 (29%), Gaps = 72/323 (22%)

Query: 449 VNQESEQSDDELLTLSSPHGNA--NGDKPHGVKKPSKKQQ--------EPAAPPPPEDVD 498
           +N++  Q +   L   +P G +   G+KP G   P  K Q        +P  PPPP    
Sbjct: 19  LNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPG--- 75

Query: 499 LLGLEGSAMSNSFSPPAAPPTNSELLSDLFGGGGAAGPTQAGQSGVEDVFHPSGPASTQS 558
                         P   PP   +  S     G   GP   G  G +    P  P   Q 
Sbjct: 76  -------------KPQGPPPQGDKSRSPRSPPGKPQGPPPQG--GNQPQGPPPPPGKPQG 120

Query: 559 TPRRSATSTSASPTLRVGEGATFDPFGAPSKPSGQDLLGSFLNTSSASSDPFLQPTRSPS 618
            P +        P               P KP G    G        S  P   P +   
Sbjct: 121 PPPQGGNRPQGPPP--------------PGKPQGPPPQGD------KSRSPRSPPGKPQG 160

Query: 619 PTVHASSTPAVNIQPDVSGGWDWHAKPGGFGMGSKSAATSPTGSSHGTPTHQSKPQTLDP 678
           P     + P     P    G      P G   G K     P G   G P    K ++   
Sbjct: 161 PPPQGGNQPQ---GPPPPPGKPQGPPPQG---GKKPQGPPPPGKPQGPPPQGDKSRS--- 211

Query: 679 FADLGTLGSSSFASKPTTPTGLGGGFPPLSSPQKASPQPMGGGWQQGGAYNWQQPQPKPQ 738
                   S S   KP  P   GG  P    P    PQ   G   QGG     +PQ  P 
Sbjct: 212 --------SQSPPGKPQGPPPQGGNQPQGPPPPPGKPQ---GPPPQGG----NKPQGPPP 256

Query: 739 PSMPHSSPQNRPNYNVSFSAMPG 761
           P  P   P    + + S  + PG
Sbjct: 257 PGKPQGPPAQGGSKSQSARSPPG 279



 Score = 34.7 bits (78), Expect = 0.42
 Identities = 52/245 (21%), Positives = 67/245 (27%), Gaps = 46/245 (18%)

Query: 531 GGAAGPTQAGQSGVEDVFHPSGPASTQSTPRRSATSTSASPTLRVGEGATFDPFGAPSKP 590
           G   GP+  G  G +    P  P   Q  P +        P               P KP
Sbjct: 34  GNPQGPSPQG--GNKPQGPPPPPGKPQGPPPQGGNKPQGPPP--------------PGKP 77

Query: 591 SGQDLLGSFLNTSSASSDPFLQPTRSPSPTVHASSTPAVNIQPDVSGGWDWHAKPGGFGM 650
            G    G        S  P   P +   P     + P     P    G      P G   
Sbjct: 78  QGPPPQGD------KSRSPRSPPGKPQGPPPQGGNQPQ---GPPPPPGKPQGPPPQG--- 125

Query: 651 GSKSAATSPTGSSHGTPTHQSKPQTLDPFADLGTLGSSSFASKPTTPTGLGGGFPPLSSP 710
           G++     P G   G P    K ++                  P +P G   G PP    
Sbjct: 126 GNRPQGPPPPGKPQGPPPQGDKSRS------------------PRSPPGKPQGPPPQGGN 167

Query: 711 QKASPQPMGGGWQQGGAYNWQQPQPKPQPSMPHSSPQNRPNYNVSFSAMPGGQNERGKGS 770
           Q   P P  G  Q       ++PQ  P P  P   P        S S     Q    +G 
Sbjct: 168 QPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGG 227

Query: 771 SNLEG 775
           +  +G
Sbjct: 228 NQPQG 232


>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
           [Homo sapiens]
          Length = 2191

 Score = 53.5 bits (127), Expect = 9e-07
 Identities = 82/342 (23%), Positives = 117/342 (34%), Gaps = 48/342 (14%)

Query: 453 SEQSDDELLTLSSPHGNANGDKPHGVKKPSKKQQEPAAPPPPEDVDLLGLEG---SAMSN 509
           S+ S  + + +  P     G  PH   + S      +  PP      +G++G    AM+ 
Sbjct: 455 SQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAG 514

Query: 510 SFSPPAAPPTNSE------LLSDLFGGGGAAGPTQAGQSGV--EDVFHPSGPASTQSTPR 561
              P      ++       L+   +G  G +G  Q GQ     +    P  P   Q  P 
Sbjct: 515 MQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPS 574

Query: 562 RSATSTSASPTL-RVGEGATFDPFGAPSKPSGQDLLGSFLNTSSASSDPFLQPTRSPSPT 620
           +S         + + G G    P  AP KP+ +DL  + +     SS P L  +    PT
Sbjct: 575 QSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDL--NLIQQERPSSLPDLSGSIDDLPT 632

Query: 621 -VHASSTPAVNIQPDVSGGWDWHAKPGGFGMGSKSAATSPTGSSHGTPTHQSKPQTLDPF 679
              A+ + AV+     S   D             + A SP  S H +P   S P    P 
Sbjct: 633 GTEATLSSAVSASGSTSSQGD-----------QSNPAQSPF-SPHASPHLSSIPGGPSPS 680

Query: 680 ADLGTLGSSSFASKPTTPTGLGGGFPPLSSPQKAS-----------PQPMGGGWQQGGAY 728
                +GS+   S P +P  + G   P   P   S           P P   G+  G   
Sbjct: 681 PVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQR 740

Query: 729 NWQQPQPKPQPSMPHSSPQNRPNYNVSFSAMPGGQNERGKGS 770
           N Q  Q  PQ + P  SP             PGGQ   G  S
Sbjct: 741 NPQMAQYGPQQTGPSMSPH----------PSPGGQMHAGISS 772



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 60/217 (27%), Positives = 83/217 (38%), Gaps = 40/217 (18%)

Query: 529 GGGGAAGPTQAGQSGVEDVFHPSGPASTQSTPRRSATSTSASPTLRVGEGATFDPFGAPS 588
           GGG   GP   G + +      S     Q    ++   + A+PTL            +PS
Sbjct: 317 GGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLN-------QLLTSPS 369

Query: 589 KPSGQDLLGSFLNTSSASSDPFLQPTRSPSPTVHASSTPAVNIQPDVSGGWDWHAKPG-G 647
            P  +   GS+   SS S+ P       P P+   S   A       +GG    A  G G
Sbjct: 370 -PMMRSYGGSYPEYSSPSAPP-------PPPSQPQSQAAAAGA---AAGGQQAAAGMGLG 418

Query: 648 FGMGSKSAATSPTGSSHGTPTHQS-KPQTLDPFADLGTLGSSSFASKPTTPTGL------ 700
             MG++ AA SP  ++    +H +  P T  P     T+G S     P  P  +      
Sbjct: 419 KDMGAQYAAASPAWAAAQQRSHPAMSPGTPGP-----TMGRSQ--GSPMDPMVMKRPQLY 471

Query: 701 GGGFPPLSSPQKASPQPMGGGWQQGGAYNWQQPQPKP 737
           G G  P S PQ++SP P       GG+Y    PQ  P
Sbjct: 472 GMGSNPHSQPQQSSPYP-------GGSYGPPGPQRYP 501



 Score = 39.3 bits (90), Expect = 0.017
 Identities = 76/320 (23%), Positives = 108/320 (33%), Gaps = 75/320 (23%)

Query: 484 KQQEPAAPPPP--EDVDLLGLEGSAMSNSFSPPAAPPTNSELLSDLFGGGGAAGPTQAGQ 541
           + Q P AP  P  ED++L+  E          P++ P  S  + DL  G      T+A  
Sbjct: 594 RSQPPLAPGKPNHEDLNLIQQER---------PSSLPDLSGSIDDLPTG------TEATL 638

Query: 542 SGVEDVFHPSGPASTQSTPRRSATSTSASPTLR-VGEGATFDPFGAP-------SKP-SG 592
           S        +     QS P +S  S  ASP L  +  G +  P G+P       S P S 
Sbjct: 639 SSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISP 698

Query: 593 QDLLGSFL------NTSSASSDPFLQPT-------------RSPSPTVHASSTPAVNIQP 633
             + GS +      + S +SS P L  +             R+P    +       ++ P
Sbjct: 699 ASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSP 758

Query: 634 DVSGGWDWHAKPGGFGMGSKSAATSPTGSSHGTPTHQSKPQTLDPFADLGTLGSSSFASK 693
             S G   HA    F   + S    P  S +G   + S+P              S   S 
Sbjct: 759 HPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAY-----------SGVPSA 807

Query: 694 PTTPTGLGGGFPPLSSPQKASP-QPMGGGWQQGGAYNWQQPQPKPQPSMPHSSPQNRP-- 750
             +  G G G    +      P QP G                 P   MP +  QNRP  
Sbjct: 808 SYSGPGPGMGISANNQMHGQGPSQPCGA---------------VPLGRMPSAGMQNRPFP 852

Query: 751 -NYNVSFSAMPGGQNERGKG 769
            N +    + PG   + G G
Sbjct: 853 GNMSSMTPSSPGMSQQGGPG 872



 Score = 32.0 bits (71), Expect = 2.7
 Identities = 78/363 (21%), Positives = 112/363 (30%), Gaps = 76/363 (20%)

Query: 470 ANGDKPHGVKKPSKKQQEPAAPPPPEDVDLLGLEGSAMSNSF--------SPPAAPPTNS 521
           A G    G ++ + + Q P+   P   ++ L    S M  S+        SP A PP  S
Sbjct: 336 AAGSAAGGFQRFAGQNQHPSGATPT--LNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPS 393

Query: 522 ELLSDLFGGGGAAGPTQAG-------QSGVEDVFHPSGPASTQSTPRRSATSTSASPTLR 574
           +  S     G AAG  QA          G +        A+ Q     + +  +  PT+ 
Sbjct: 394 QPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMG 453

Query: 575 VGEGATFDP--------FGAPSKPSGQDLLGS-FLNTSSASSDPFLQPTRSPSPTVHASS 625
             +G+  DP        +G  S P  Q    S +   S     P   P      T  A +
Sbjct: 454 RSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMA 513

Query: 626 TPAVNIQPDVSGGWDWH----AKPGGFGM----GSKSAATSPTGSSHGTPTH-------- 669
                 Q D SG   W       P  +G     G       P  S    P H        
Sbjct: 514 GMQYPQQQD-SGDATWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYL 572

Query: 670 -QSKPQTLDPFADLGTLGSSSFASKPTTP-------------------TGLGGGFPPLSS 709
                Q   P  D+   G  + +  P  P                     L G    L +
Sbjct: 573 PSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPT 632

Query: 710 PQKASPQPMGGGWQQGGAYNWQ--QPQPKPQPSMPHSSPQNRPNYNVSFSAMPGGQNERG 767
             +A+   +       G+ + Q  Q  P   P  PH+SP          S++PGG +   
Sbjct: 633 GTEAT---LSSAVSASGSTSSQGDQSNPAQSPFSPHASPH--------LSSIPGGPSPSP 681

Query: 768 KGS 770
            GS
Sbjct: 682 VGS 684



 Score = 31.2 bits (69), Expect = 4.6
 Identities = 32/139 (23%), Positives = 53/139 (38%), Gaps = 6/139 (4%)

Query: 484  KQQEPAAPPPPEDVDLLGLEGSAMSNSFSPPAAPPTNSELLSDLFGGGGAAGPTQAGQSG 543
            K+Q    PP P +   L    +  S   +  A  P + +  +      G   P Q G+S 
Sbjct: 1115 KKQPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSS 1174

Query: 544  VEDVFHPSGPASTQSTPRRSATSTSASPTLRVGEGATF-DPFGAPSKPSGQDLLGSFLNT 602
               V  P    S  S P+R+    S +P     +G +  D  G       +D  G  +  
Sbjct: 1175 TISVHDPFSDVSDSSFPKRN----SMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGG-MRK 1229

Query: 603  SSASSDPFLQPTRSPSPTV 621
               SS+PF+   + P+ ++
Sbjct: 1230 VPGSSEPFMTQGQMPNSSM 1248


>gi|54860079 nadrin isoform 1 [Homo sapiens]
          Length = 881

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 81/321 (25%), Positives = 116/321 (36%), Gaps = 97/321 (30%)

Query: 450 NQESEQSDDELLTLSSPHGNANGDKPHGVKKPSKKQQEPAAPPPPEDVDLLGLEGSAMSN 509
           NQ    +    L++  PH NA G  PH +++  KK     AP PP+              
Sbjct: 602 NQPQAAAGSHQLSMGQPH-NAAGPSPHTLRRAVKKP----APAPPK-------------- 642

Query: 510 SFSPPAAPPTNSELLSDLFGGGGAAGPTQAGQSGVEDVFHPSGPASTQSTPRRSATSTSA 569
               P  PP          GG  ++G +Q          HP  P+ +   P RS +    
Sbjct: 643 ----PGNPPPGHP------GGQSSSGTSQ----------HP--PSLSPKPPTRSPSP--- 677

Query: 570 SPTLRVGEGATFDPFGAPSKPSGQDLLGSFLNTSSASSDPFLQPTRSPSPTVHASSTPAV 629
            PT   G+     P G PS PS       +    S+S  P   P   P P     +TP +
Sbjct: 678 -PTQHTGQ-----PPGQPSAPSQLSAPRRY----SSSLSPIQAPNHPP-PQPPTQATPLM 726

Query: 630 NIQPDVSGGWDWHAKPGGFGMGSKSAATSPTGSSHGTPTHQSKPQTLDPFADLGTLGSSS 689
           + +P+  G  +  A P   G+                P+H + PQT  P           
Sbjct: 727 HTKPNSQGPPNPMALPSEHGLEQ--------------PSH-TPPQTPTP----------- 760

Query: 690 FASKPTTPTGLGGGFPPLSSPQKASPQPMGGGWQQGGAYNWQQPQPKPQPSMPHSSPQNR 749
               P+TP  LG   P L +PQ  +    GG  +    +    P+P+P P      P+NR
Sbjct: 761 ----PSTPP-LGKQNPSLPAPQTLA----GGNPETAQPHAGTLPRPRPVP-----KPRNR 806

Query: 750 PNYNVSFSAMPGGQNERGKGS 770
           P  +V     P G +  G  S
Sbjct: 807 P--SVPPPPQPPGVHSAGDSS 825


>gi|54860105 nadrin isoform 2 [Homo sapiens]
          Length = 803

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 81/321 (25%), Positives = 116/321 (36%), Gaps = 97/321 (30%)

Query: 450 NQESEQSDDELLTLSSPHGNANGDKPHGVKKPSKKQQEPAAPPPPEDVDLLGLEGSAMSN 509
           NQ    +    L++  PH NA G  PH +++  KK     AP PP+              
Sbjct: 524 NQPQAAAGSHQLSMGQPH-NAAGPSPHTLRRAVKKP----APAPPK-------------- 564

Query: 510 SFSPPAAPPTNSELLSDLFGGGGAAGPTQAGQSGVEDVFHPSGPASTQSTPRRSATSTSA 569
               P  PP          GG  ++G +Q          HP  P+ +   P RS +    
Sbjct: 565 ----PGNPPPGHP------GGQSSSGTSQ----------HP--PSLSPKPPTRSPSP--- 599

Query: 570 SPTLRVGEGATFDPFGAPSKPSGQDLLGSFLNTSSASSDPFLQPTRSPSPTVHASSTPAV 629
            PT   G+     P G PS PS       +    S+S  P   P   P P     +TP +
Sbjct: 600 -PTQHTGQ-----PPGQPSAPSQLSAPRRY----SSSLSPIQAPNHPP-PQPPTQATPLM 648

Query: 630 NIQPDVSGGWDWHAKPGGFGMGSKSAATSPTGSSHGTPTHQSKPQTLDPFADLGTLGSSS 689
           + +P+  G  +  A P   G+                P+H + PQT  P           
Sbjct: 649 HTKPNSQGPPNPMALPSEHGLEQ--------------PSH-TPPQTPTP----------- 682

Query: 690 FASKPTTPTGLGGGFPPLSSPQKASPQPMGGGWQQGGAYNWQQPQPKPQPSMPHSSPQNR 749
               P+TP  LG   P L +PQ  +    GG  +    +    P+P+P P      P+NR
Sbjct: 683 ----PSTPP-LGKQNPSLPAPQTLA----GGNPETAQPHAGTLPRPRPVP-----KPRNR 728

Query: 750 PNYNVSFSAMPGGQNERGKGS 770
           P  +V     P G +  G  S
Sbjct: 729 P--SVPPPPQPPGVHSAGDSS 747


>gi|239752594 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 673

 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 87/335 (25%), Positives = 127/335 (37%), Gaps = 60/335 (17%)

Query: 464 SSPHGNANGDKPHGVKKPSKKQQEPAAPP-PPEDVDLLGLEGSAMSNSFSPPAAPPTNSE 522
           +SP G  +   P G   PS+     A+P   P    L GL  +A S + +PP A PT + 
Sbjct: 347 ASPTGKPSTASPTGT--PSR-----ASPTGSPSTASLTGLSSTA-SPTGTPPRASPTGTP 398

Query: 523 LLSDLFGGGGAAGPT-QAGQSGVEDVFHPSGPASTQSTPRRSATSTS--ASPT------L 573
             + L      A PT    ++ +  +   + P  T++ PR S T T   ASPT       
Sbjct: 399 STASLTRKPPRASPTGMLSRTSITKMDSTASP--TRTPPRASPTGTPPRASPTGTPSRAS 456

Query: 574 RVGEGATFDPFGAPS--KPSGQDLLGSFLNTSSASSDPFLQPTRSPSPTVHASSTPAVNI 631
             G  +T  P G+PS   P+G     S   + S +S   L  T S +      ST ++  
Sbjct: 457 PTGTQSTASPTGSPSTASPTGSPSTASPTGSPSRAS---LTRTPSRASLTKMESTASITR 513

Query: 632 QPD-VSGGWDWH-AKPGG-----FGMGSKSAAT------------SPTGSSHGTPTHQSK 672
            P   S  W    A P G       MGS S A             +P+ +S  TP+  S 
Sbjct: 514 TPSRASPTWTPSTASPTGSPSTALAMGSPSRAALTRTPSRASLTRTPSRASLTTPSRASL 573

Query: 673 PQTLDPFADLGTLGSSSFASKP--TTPTGLGGGF--------------PPLSSPQKASPQ 716
            +T           S+S    P  T+PTG+                  PP +SP +  P+
Sbjct: 574 TRTPSTVLLTRMPPSASPTGMPSRTSPTGMPSSALLTKMDSTASITRTPPRASPTETPPR 633

Query: 717 PMGGGWQQGGAYNWQQPQPKPQPSMPHSSPQNRPN 751
               G     +     P+  P  + P +SP   P+
Sbjct: 634 ASPTGTPPRASPTGTPPRASPTGTPPRASPTGTPS 668



 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 64/225 (28%), Positives = 79/225 (35%), Gaps = 45/225 (20%)

Query: 505 SAMSNSFSPPAAPPTNSELLSDLFGGGGAAGPTQAGQSGVEDVFHPSGPASTQSTPRRSA 564
           S  S S +PP A  T +   +   G    A PT     G      P+G  ST S    + 
Sbjct: 327 STASISRTPPRASITRTPSRASPTGKPSTASPT-----GTPSRASPTGSPSTASL---TG 378

Query: 565 TSTSASPTLRVGEGATFDPFGAPS------KPSGQDLLGSFLNTSSASSDPFLQPTRSPS 618
            S++ASPT   G      P G PS      KP      G    TS    D    PTR+P 
Sbjct: 379 LSSTASPT---GTPPRASPTGTPSTASLTRKPPRASPTGMLSRTSITKMDSTASPTRTP- 434

Query: 619 PTVHASSTPAVNIQPDVSGGWDWHAKPGGFGMGSKSAATSPTGSSHGTPTHQS---KPQT 675
           P    + TP               A P G    +    T  T S  G+P+  S    P T
Sbjct: 435 PRASPTGTPP-------------RASPTGTPSRASPTGTQSTASPTGSPSTASPTGSPST 481

Query: 676 LDPFADLGTLGSSSFASKPTTP-----TGLGGGFPPLSSPQKASP 715
             P       GS S AS   TP     T +        +P +ASP
Sbjct: 482 ASP------TGSPSRASLTRTPSRASLTKMESTASITRTPSRASP 520



 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 69/324 (21%), Positives = 101/324 (31%), Gaps = 58/324 (17%)

Query: 446 AALVNQESEQSDDELLTLSSPHGNANGDKPHGVKKPSKKQQEPAA------PPPPEDVDL 499
           A+L   +S  S    L+ +SP G      P G    +     P+       PP      +
Sbjct: 200 ASLTKMDSTASITRTLSRASPTGTPPRASPTGSPPRASLSMMPSTALLIRTPPRASPTGM 259

Query: 500 LGLEGSAMSNSFS--------PPAAPPTNSELLSDLFGGGGAAG-------PTQAGQSGV 544
           L        +S +        P  A PT +   + L      A         +  G    
Sbjct: 260 LSRTSLTKMDSTASITRTPSRPSTASPTGTPSRASLSMTPSTASLMRMLPRASPTGMLSR 319

Query: 545 EDVFHPSGPASTQSTPRRSATSTSASPTLRVGEGATFDPFGAPSK--PSGQDLLGSFLNT 602
             +      AS   TP R++ + + S     G+ +T  P G PS+  P+G     S    
Sbjct: 320 TSLTKMDSTASISRTPPRASITRTPSRASPTGKPSTASPTGTPSRASPTGSPSTASLTGL 379

Query: 603 SSASSDPFLQPTRSPSPTVHASSTPAVNIQPDVSGGWDWHAKPGGFGMGSKSAATSPTGS 662
           SS +S     P  SP+ T    ST ++  +P         A P G    +       T S
Sbjct: 380 SSTASPTGTPPRASPTGT---PSTASLTRKPP-------RASPTGMLSRTSITKMDSTAS 429

Query: 663 SHGTPTHQSKPQTLDPFADLGTLGSSSFASKPTTPTGLGGGFPPLSSPQKASPQPMGGGW 722
              TP   S                         PTG      P  +P +ASP       
Sbjct: 430 PTRTPPRAS-------------------------PTGTPPRASPTGTPSRASPTGTQSTA 464

Query: 723 QQGGAYNWQQPQPKPQPSMPHSSP 746
              G+ +   P   P  + P  SP
Sbjct: 465 SPTGSPSTASPTGSPSTASPTGSP 488



 Score = 37.0 bits (84), Expect = 0.084
 Identities = 69/302 (22%), Positives = 102/302 (33%), Gaps = 67/302 (22%)

Query: 505 SAMSNSFSPPAAPPTNSELLSDLFGGGGAAGPTQAGQSGVEDVFHPSGPASTQSTPRRSA 564
           S  S + +PP A  T +   + L        P +A  +G+     P+G  ST S  +  +
Sbjct: 153 SRASLTRTPPRASLTMTPSTASL-----TRTPPRASPTGMPSRTSPTGMPSTASLTKMDS 207

Query: 565 TST------SASPTLRVGEGATFDPFGAPSK---------------PSGQDLLGSFLNTS 603
           T++       ASPT   G      P G+P +               P      G    TS
Sbjct: 208 TASITRTLSRASPT---GTPPRASPTGSPPRASLSMMPSTALLIRTPPRASPTGMLSRTS 264

Query: 604 SASSDPFLQPTRSPSPTVHASST-----PAVNIQPDVSGGWDWHAKPGGFGMGSKSAATS 658
               D     TR+PS    AS T      ++++ P  +       +    GM S+++ T 
Sbjct: 265 LTKMDSTASITRTPSRPSTASPTGTPSRASLSMTPSTASLMRMLPRASPTGMLSRTSLTK 324

Query: 659 -----------PTGSSHGTPTHQS---KPQTLDPFADLGTLGSSSFASKPTTP--TGLGG 702
                      P  S   TP+  S   KP T  P    GT   +S    P+T   TGL  
Sbjct: 325 MDSTASISRTPPRASITRTPSRASPTGKPSTASP---TGTPSRASPTGSPSTASLTGLSS 381

Query: 703 GFPPLSSPQKASP--------------QPMGGGWQQGGAYNWQQPQPKPQPSMPHSSPQN 748
              P  +P +ASP              +    G     +         P  + P +SP  
Sbjct: 382 TASPTGTPPRASPTGTPSTASLTRKPPRASPTGMLSRTSITKMDSTASPTRTPPRASPTG 441

Query: 749 RP 750
            P
Sbjct: 442 TP 443


>gi|7662228 synaptosomal-associated protein, 91kDa homolog [Homo
           sapiens]
          Length = 907

 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 83/317 (26%), Positives = 124/317 (39%), Gaps = 52/317 (16%)

Query: 487 EPAAPPPPEDVDLLGLEGSAMSNSFSPPAAPPTNSELLSDLFGGGGAAGPTQA------- 539
           E AA P P+    + L  +   +S    A+P   S L +DL      A P+ A       
Sbjct: 573 EVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAK 632

Query: 540 -GQSGVEDVFHPS-GPASTQSTP-RRSATSTSASPTLRVGEGATF-DPFGAPSKPSGQDL 595
              SGV D+F  + G ++++  P  ++A+S+SAS  L  G G +F  P  +P  P+  +L
Sbjct: 633 VDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNL 692

Query: 596 L--------GSFLNTSSASS-DP--------FLQPTRSPSPTVHASSTPAVNIQPDVSGG 638
           L        G+  +TSS+SS DP         L PT +P+        P   + P  +  
Sbjct: 693 LQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPA----GQPAPVSMVPPSPA-- 746

Query: 639 WDWHAKPGGFGMGSKSAATSPTGSSHGTPTHQSKPQTLDPFADLGTLGSSSFASKPTTPT 698
               A     G    S+  S  G+   + T   K        +    G +++  K   P 
Sbjct: 747 ---MAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQPK-VAPA 802

Query: 699 GLGGGFPPLSSPQKASP-----QPMGGGWQQG--GAYNWQQPQPKPQPSMPH-----SSP 746
               G PP +  Q A P      P+ G    G  GA     P     P MP      + P
Sbjct: 803 TWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAGTGMPMMPQQPVMFAQP 862

Query: 747 QNRPNYNVSFSAMPGGQ 763
             RP +    +A+PG Q
Sbjct: 863 MMRPPFGA--AAVPGTQ 877



 Score = 38.9 bits (89), Expect = 0.022
 Identities = 81/358 (22%), Positives = 116/358 (32%), Gaps = 74/358 (20%)

Query: 488 PAAPPPPEDV----DLLGLEGSA----------MSNSFSPPAAPPTNSELLSDLFGGGGA 533
           PA PPP        DLLG +  A          +S+ F+P   PPT +  ++        
Sbjct: 367 PAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATASASAST 426

Query: 534 AGPTQAGQSGVEDVFHPSGPASTQSTPRRS------ATSTSASPTLRVGEGATFDPFGAP 587
                A  + V D+F  +  AS    P  S      AT T  +  L    G   DPF AP
Sbjct: 427 TTTVTAVTAEV-DLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGN--DPF-AP 482

Query: 588 SKPSGQDL--LGSFLNTSSASSDPFLQPTRSPSPTVHASS-----------------TPA 628
           S+ S +    L  F      +S P + PT S +P V A++                 T A
Sbjct: 483 SEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAA 542

Query: 629 VNIQPDVSGGWDWHAKPGGFGMGSKSAAT-----------SPTGSSHGTPTHQSKPQTLD 677
                  S      A P     G    +T           +P+     T    S PQ   
Sbjct: 543 ATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSPPQGAS 602

Query: 678 PF------ADLGTLGSSSFASKPTTPT-------GLGGGFPPLSSPQKASPQPMGGGWQQ 724
           P       ADL ++ + +  S  TT +       G+   F        + PQP       
Sbjct: 603 PVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASS 662

Query: 725 GGA-------YNWQQPQPKPQPSMPHSSPQNRPNYNVSFSAMPGGQNERGKGSSNLEG 775
             A       +      P P P  P  +   +PN+  +F   P   +      S  +G
Sbjct: 663 SSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDG 720


>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
           sapiens]
          Length = 309

 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 83/336 (24%), Positives = 102/336 (30%), Gaps = 69/336 (20%)

Query: 447 ALVNQESEQSDDELLTLSSPHGNANGDKPHGVKKPSKKQQEPAAPPPPEDVDLLGLEGSA 506
           AL+   S QS +E ++        +G KP G ++P    Q    PPPP   +    +G  
Sbjct: 9   ALLALSSAQSLNEDVSQEESPSVISG-KPEG-RRPQGGNQPQRTPPPPGKPEGRPPQGGN 66

Query: 507 MSNSFSP----PAAPPTNSELLSDLFGGGGAAGPTQAGQSGVEDVFHPSGPASTQSTPRR 562
            S    P    P  PP          GG  + GP    + G  +   P G   +Q  P R
Sbjct: 67  QSQGPPPRPGKPEGPPPQ--------GGNQSQGPPP--RPGKPEGQPPQGGNQSQGPPPR 116

Query: 563 SATSTSASPTLRVGEGATFDPFGAPSKPSGQDLLGSFLNTSSASSDPFLQPTRSPSPTVH 622
                   P    G   +  P   P KP G    G                ++ P P   
Sbjct: 117 PGKPEGPPPQ---GGNQSQGPPPRPGKPEGPPPQGG-------------NQSQGPPPR-- 158

Query: 623 ASSTPAVNIQPDVSGGWDWHAKPGGFGMGSKSAATSPTGS--SHGTPTHQSKPQTLDPFA 680
               P     P   GG      P   G   K     P G   S G P    KP+   P  
Sbjct: 159 ----PGKPEGPPPQGGNQSQGPPPHPG---KPEGPPPQGGNQSQGPPPRPGKPEGPPPQG 211

Query: 681 DLGTLGSSSFASKPTTPTGLGGGFPPLSSPQKASPQ-----------------------P 717
              + G      KP  P   GG  P    P    PQ                       P
Sbjct: 212 GNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPP 271

Query: 718 MGGGWQQ---GGAYNWQQPQPKPQPSMPHSSPQNRP 750
            GG  QQ     A   Q P P PQ   PH  PQ +P
Sbjct: 272 PGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPPQGQP 307


>gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens]
          Length = 753

 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 73/322 (22%), Positives = 120/322 (37%), Gaps = 33/322 (10%)

Query: 433 DQKSEKSFCEEDHAALVNQESEQSDDELLTLSSPHGNANGDKPHGVKKPSKKQQEPAAPP 492
           D   +  F EE+     + + E     L+  S P  +   D+       +      ++P 
Sbjct: 212 DSSQDPDF-EENEFLYDDLDLEDIPQALVATSPPSHSHMEDEIFNQSSSTPTSTTSSSPI 270

Query: 493 PPEDVDLLGLEGSAMSNSFSPPAAPPTNSELL-SDLFGGGGAAGPTQAGQSGVEDVFHPS 551
           PP   +      +  ++         T+SE+  S    G       Q  QS      +PS
Sbjct: 271 PPSPANC-----TTENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPS 325

Query: 552 GP----ASTQSTPRRSATSTSASPTLRVGEGATFDPFGAPSKPSGQDLLGSFLNTSSASS 607
           GP    ++  +TP  +     A+P   +G  A+     APS  SG             + 
Sbjct: 326 GPPPAASALSTTPGNNGVPAPAAPPSALGPKAS----PAPSHNSG-------------TP 368

Query: 608 DPFLQPTRSPSPTVHASSTPAV-NIQPDVSGGWDWHAKPGGFGMGSKSAATSPTGSSHGT 666
            P+ Q    P+P+  +++ P   ++QP  SGG    +  GG    S S+A    G  +G 
Sbjct: 369 APYAQAVAPPAPSGPSTTQPRPPSVQP--SGGGGGGSGGGGSSSSSNSSAGGGAGKQNGA 426

Query: 667 PTHQSKPQTLDPFADLGTLGSSSFASKPTTPTGLGGGFPPLSSPQKASPQPMG-GGWQQG 725
            ++ S          L + G ++ +S+   P       PP +S + ++  P G GG   G
Sbjct: 427 TSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTGAGGVAPG 486

Query: 726 GAYNWQQPQ-PKPQPSMPHSSP 746
              N   P    P P  P SSP
Sbjct: 487 SGNNSGGPSLLVPLPVNPPSSP 508


>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
          Length = 1970

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 74/307 (24%), Positives = 111/307 (36%), Gaps = 42/307 (13%)

Query: 465  SPHGNANGDKPHGVKKPSKKQQEPAAPPPPEDVDLLGLEGSAMSNSFSP------PAAP- 517
            S   +A+G  P      S     P +P P      +   G AMS S+SP      P +P 
Sbjct: 1549 SAASDASGFSPGYSPAWSPTPGSPGSPGPSSPY--IPSPGGAMSPSYSPTSPAYEPRSPG 1606

Query: 518  ------PTNSELLSDLFGGGGAAGPTQAGQSGVEDVFHPSGPASTQSTPRRSATSTSASP 571
                  P+ S           +  PT    S     + P+ P+ + ++P  S TS S SP
Sbjct: 1607 GYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP 1666

Query: 572  TLRVGEGATFDPFGAPSKPSGQDLLGSFLNTSSASSDPFLQPTRSPSPTVHASSTPAVN- 630
            T          P  +P+ PS      S+  TS + S     P+ SP+   ++ ++P+ + 
Sbjct: 1667 T---------SPSYSPTSPSYSPTSPSYSPTSPSYSP--TSPSYSPTSPSYSPTSPSYSP 1715

Query: 631  IQPDVSGGWDWHAKPGGFGMGSKSAATSPTGSSHGTPTHQSKPQTLDPFADLGTLGSSSF 690
              P  S        P        S + SPT  S+   +    P + +      +   +S 
Sbjct: 1716 TSPSYS--------PTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSP 1767

Query: 691  ASKPTTP--TGLGGGFPPLS---SPQKASPQPMGGGWQQGG-AYNWQQPQPKP-QPSMPH 743
            +  PT+P  T     + P S   SP   S  P    +      Y  Q P   P  PS   
Sbjct: 1768 SYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSP 1827

Query: 744  SSPQNRP 750
            SSP   P
Sbjct: 1828 SSPSYSP 1834



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 70/279 (25%), Positives = 100/279 (35%), Gaps = 26/279 (9%)

Query: 481  PSKKQQEPAAPPPPEDVDLLGLEGSAMSNSFSPPAAPPTNSELLSDLFGGGGAAGPTQAG 540
            PS     P+  P            S  S S+SP +  P+ S    +         PT   
Sbjct: 1704 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTS--PSYSPTSPNYSPTSPNYTPTSPS 1761

Query: 541  QSGVEDVFHPSGPASTQSTPRRSATSTSASPTLRVGEGATFDPFGAPSKP--SGQDLLGS 598
             S     + P+ P  T ++P  S TS S SPT      +   P  +PS P  + Q    +
Sbjct: 1762 YSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPT--SPSYSPTSPSYSPSSPRYTPQSPTYT 1819

Query: 599  FLNTSSASSDPFLQPTRSP-----SPTVHASSTPAVNIQPDVSGGWDWHAKPGGFGMGSK 653
              + S + S P   PT SP     SP+   SS       P  S        P       K
Sbjct: 1820 PSSPSYSPSSPSYSPT-SPKYTPTSPSYSPSSPEYTPTSPKYS-----PTSPKYSPTSPK 1873

Query: 654  SAATSPTGSSHGTPTHQSKPQTLDPFADLGTLGSSSFASKPTTPTGLGGGFPPLSSPQKA 713
             + TSPT  S  TP +     T  P + + T  S  ++  PT+PT     + P S     
Sbjct: 1874 YSPTSPT-YSPTTPKYSPTSPTYSPTSPVYTPTSPKYS--PTSPT-----YSPTSPKYSP 1925

Query: 714  SPQPMGGGWQQGGAYNWQQPQPKP-QPSMPHSSPQNRPN 751
            +         +G  Y+   P   P  P+   +SP   P+
Sbjct: 1926 TSPTYSPTSPKGSTYSPTSPGYSPTSPTYSLTSPAISPD 1964


>gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]
          Length = 987

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 82/314 (26%), Positives = 111/314 (35%), Gaps = 54/314 (17%)

Query: 427 ASLCWQDQKSEKSFCEEDHAALVNQESEQSDDELLTLSSPHGNANGDKPHGVKKPS---- 482
           ASL W +Q  E    + D A+    E+  +     T + P   A    P  +  PS    
Sbjct: 277 ASLQWFNQALED---KSDAASNSVTETPPTTQPSFTFTLPAA-ATASPPTSLLAPSTNPL 332

Query: 483 -----KKQQEPAAPPPPEDVDLLGLEGSAMSNSFSPPAAPPTNSELLSDLFGGGGAAGPT 537
                K Q  P+ PP PE        G+A + + SPP  P     LL  L  G   +GP 
Sbjct: 333 LESLKKMQTPPSLPPCPESA------GAATTEALSPPKTP----SLLPPL--GLSQSGPP 380

Query: 538 QAGQSGVEDVFHPSGPASTQSTPRR-SATSTSASPTLRVGEGATFDPFGAPSKPSGQDLL 596
               S   D   P+        P    AT T A PTL+           APS    Q  L
Sbjct: 381 GLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPKQSFL 440

Query: 597 GSFLNTSSASSDPFLQPTRSPSPTVHASSTPAVNIQPDVSGGWDWHAKPGGFGMGSKSAA 656
               NTS +            SP   A+S+ +   +P +        K G    G    A
Sbjct: 441 FGTQNTSPS------------SPAAPAASSASPMFKP-IFTAPPKSEKEGPTPPGPSVTA 487

Query: 657 TSPTGSSHGTPTHQSKPQTLDPFADLGTLGS----SSFASKPTTP-----------TGLG 701
           T+P+ SS  T T  + P     F+ +G   S    + F  + TTP           TGL 
Sbjct: 488 TAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLA 547

Query: 702 GGFPPLSSPQKASP 715
                ++    ASP
Sbjct: 548 SATSAVAPITSASP 561



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 56/242 (23%), Positives = 86/242 (35%), Gaps = 47/242 (19%)

Query: 493 PPEDVDLLGLEGSAMSNSFSPPAAPPTNSELLSDLFGGGGAAGPTQAGQSGVEDVFHPS- 551
           PP  V L          + +P  AP T + L + L     A  P  +     +    P+ 
Sbjct: 515 PPASVPL---PAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAF 571

Query: 552 ----GPASTQSTPRRSATSTSASPTLRVG----EGATFDP-------FGAPSKPSGQDLL 596
                  S+ S    ++T+T+AS     G      A+F P       FG P       L 
Sbjct: 572 GFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPA-----LP 626

Query: 597 GSFLNTSSASSDPFLQPTRSPSPTVH--------ASSTPAVNIQPDVSGGWDWHAKPGGF 648
            +   T+ + S P   PT + S            A+S PA + QP ++     +     F
Sbjct: 627 TTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFS---NTSTPTF 683

Query: 649 GMGSKSAATSPT------------GSSHGTPTHQSKPQTLDPFADLGTLGSSSFASKPTT 696
            +   S+A SP             G++ G P   +KP     F    T G+S+  +  T 
Sbjct: 684 NIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATA 743

Query: 697 PT 698
           PT
Sbjct: 744 PT 745



 Score = 32.3 bits (72), Expect = 2.1
 Identities = 78/356 (21%), Positives = 122/356 (34%), Gaps = 67/356 (18%)

Query: 437 EKSFCEEDHAALVNQESEQSDDELLTLSSPHGNANGDKPH-----GVKK------PSKKQ 485
           E+  C    ++      ++S  E    ++P    N +        G +K      PS++ 
Sbjct: 192 EEELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRG 251

Query: 486 QEPAAPPPP--------EDVDL----------LGLEGSAMSNSFSPPAAPPTNSELLSDL 527
           ++   PPPP        ED+DL            LE  + + S S    PPT     +  
Sbjct: 252 EQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPTTQPSFTFT 311

Query: 528 FGGGGAAGPTQAGQSGVEDVFHPSGPASTQSTPRRSATSTSASPTLRVGEGATFDPFGAP 587
                 A P  +       +  PS     +S  ++  T  S  P       AT +    P
Sbjct: 312 LPAAATASPPTS-------LLAPSTNPLLESL-KKMQTPPSLPPCPESAGAATTEALSPP 363

Query: 588 SKPSGQDLLGSFLNTSSASSDPFLQPT---RSPSPTVHASSTPAVNIQPDVSGGWDWHAK 644
             PS    LG      S S  P L P+    S  PT      PA ++ P      D  A 
Sbjct: 364 KTPSLLPPLG-----LSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVP----ATDTKAP 414

Query: 645 PGGFGMGSKSAATSPTGSSHGTPTHQSKPQTLDPFADLGTLGSSSFASKPTTPTGLGGGF 704
           P          AT P  +S  +P     P+    F    T  SS  A   ++ + +   F
Sbjct: 415 P----TLQAETATKPQATSAPSPA----PKQSFLFGTQNTSPSSPAAPAASSASPM---F 463

Query: 705 PPL-SSPQKASPQPMGGGWQQGGAYNWQQPQPKPQPSMPHSSPQNRPNYNVSFSAM 759
            P+ ++P K+  +   G    G +     P      S+P ++    P +   FS+M
Sbjct: 464 KPIFTAPPKSEKE---GPTPPGPSVTATAPS---SSSLPTTTSTTAPTFQPVFSSM 513


>gi|39995080 hypothetical protein LOC79567 [Homo sapiens]
          Length = 1219

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 70/271 (25%), Positives = 98/271 (36%), Gaps = 34/271 (12%)

Query: 513 PPAAPPTNSELLSDLFGGGGAAGPTQAGQSGVEDVFHPS---------GPASTQSTPRRS 563
           PPA  P +S   S L   G     T    S   D  H S         GP  T +    S
Sbjct: 495 PPALDPGHSATSSTLGTTGSVPTSTDPAPSAHLDSVHKSTDSGPSELPGPTHTTTGSTYS 554

Query: 564 A---TSTSASPTLRVGEGATFDPFGAPSKPSGQDL-LGSFLNTSSASSDPFLQPTRSPSP 619
           A   T ++ SP      G+T  P  +    +G  L +   + T+++ +     PT + + 
Sbjct: 555 AITTTHSAPSPLTHTTTGSTHKPIISTLTTTGPTLNIIGPVQTTTSPTHTMPSPTHTTAS 614

Query: 620 TVHASSTPA---VNIQPDVSGGWDWHAKPGGFGMGSKSAATSPTGSSHGTPTHQSKPQTL 676
             H S++P     +     S        P   GMG    ATSPT  +  +PTH +    L
Sbjct: 615 PTHTSTSPTHTPTSPTHKTSMSPPTTTSPTPSGMGLVQTATSPTHPT-TSPTHPTTSPIL 673

Query: 677 -----DPFADLGTLGSSSFASKPTTPTGLGGGFPPLSSPQKASPQPMGGGWQQGGAYNWQ 731
                    +L TL S S  S PT P   G    P S        P+   + Q      +
Sbjct: 674 INVSPSTSLELATLSSPSKHSDPTLP---GTDSLPCS-------PPVSNSYTQADPMAPR 723

Query: 732 QPQPKPQPS--MPHSSPQNRPNYNVSFSAMP 760
            P P P  S   P +SP   P+ +   S  P
Sbjct: 724 TPHPSPAHSSRKPLTSPAPDPSESTVQSLSP 754



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 58/255 (22%), Positives = 98/255 (38%), Gaps = 29/255 (11%)

Query: 462 TLSSPHGNANGDKPHGVKKPSKKQQEPAAPPPPEDVDLLGLEGSAMSNSFSPPA------ 515
           T + P  +A+ D  H           P+  P P      G   SA++ + S P+      
Sbjct: 517 TSTDPAPSAHLDSVH-----KSTDSGPSELPGPTHTTT-GSTYSAITTTHSAPSPLTHTT 570

Query: 516 APPTNSELLSDLFGGG---GAAGPTQAGQSGVEDVFHPSGPASTQSTPRRSATSTSASPT 572
              T+  ++S L   G      GP Q   S    +  PS P  T ++P  ++TS + +PT
Sbjct: 571 TGSTHKPIISTLTTTGPTLNIIGPVQTTTSPTHTM--PS-PTHTTASPTHTSTSPTHTPT 627

Query: 573 LRVGEGATFDPFGAPSKPSGQDLLGSFLNTSSASSDPFLQPTRSP-----SPTVHAS--- 624
               + +   P      PSG  L+ +  + +  ++ P   PT SP     SP+       
Sbjct: 628 SPTHKTSMSPPTTTSPTPSGMGLVQTATSPTHPTTSP-THPTTSPILINVSPSTSLELAT 686

Query: 625 -STPAVNIQPDVSGGWDWHAKPGGFGMGSKSAATSPTGSSHGTPTHQSKPQTLDPFADLG 683
            S+P+ +  P + G       P      +++   +P  + H +P H S+     P  D  
Sbjct: 687 LSSPSKHSDPTLPGTDSLPCSPPVSNSYTQADPMAPR-TPHPSPAHSSRKPLTSPAPDPS 745

Query: 684 TLGSSSFASKPTTPT 698
                S +  P+ PT
Sbjct: 746 ESTVQSLSPTPSPPT 760


>gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]
          Length = 984

 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 83/314 (26%), Positives = 108/314 (34%), Gaps = 54/314 (17%)

Query: 427 ASLCWQDQKSEKSFCEEDHAALVNQESEQSDDELLTLSSPHGNANGDKPHGVKKPS---- 482
           ASL W +Q  E    + D A+    E+        T + P   A    P  +  PS    
Sbjct: 277 ASLQWFNQALED---KSDAASNSVTETPPITQPSFTFTLPAA-APASPPTSLLAPSTNPL 332

Query: 483 -----KKQQEPAAPPPPEDVDLLGLEGSAMSNSFSPPAAPPTNSELLSDLFGGGGAAGPT 537
                K Q  P+ PP PE        G+A + + SPP  P     LL  L  G   +GP 
Sbjct: 333 LESLKKMQTPPSLPPCPESA------GAATTEALSPPKTP----SLLPPL--GLSQSGPP 380

Query: 538 QAGQSGVEDVFHPSGPASTQSTPRR-SATSTSASPTLRVGEGATFDPFGAPSKPSGQDLL 596
               S   D   P+        P    AT T A PTL+           APS    Q  L
Sbjct: 381 GLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPKQSFL 440

Query: 597 GSFLNTSSASSDPFLQPTRSPSPTVHASSTPAVNIQPDVSGGWDWHAKPGGFGMGSKSAA 656
               NTS +S      P  S +P +     P     P          K G    G    A
Sbjct: 441 FGTQNTSPSSP---AAPAASSAPPMF---KPIFTAPPK-------SEKEGPTPPGPSVTA 487

Query: 657 TSPTGSSHGTPTHQSKPQTLDPFADLGTLGS----SSFASKPTTP-----------TGLG 701
           T+P+ SS  T T  + P     F+ +G   S    + F  + TTP           TGL 
Sbjct: 488 TAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLA 547

Query: 702 GGFPPLSSPQKASP 715
                ++    ASP
Sbjct: 548 SATSAVAPITSASP 561



 Score = 38.5 bits (88), Expect = 0.029
 Identities = 52/236 (22%), Positives = 85/236 (36%), Gaps = 37/236 (15%)

Query: 493 PPEDVDLLGLEGSAMSNSFSPPAAPPTNSELLSDLFGGGGAAGPTQAGQSGVEDVFHPS- 551
           PP  V L          + +P  AP T + L + L     A  P  +     +    P+ 
Sbjct: 515 PPASVPL---PAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAF 571

Query: 552 ----GPASTQSTPRRSATSTSASPTLRVG----EGATFDP-------FGAPSKPSGQDLL 596
                  S+ S    ++T+T+AS     G      A+F P       FG P        +
Sbjct: 572 GFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTV 631

Query: 597 GSF---LNTSSASSDPFLQPTRSPSPTVHASSTPAVNIQPDVSGGWDWHAKPGGFGMGSK 653
            +F   L+T+  ++        S   +  A+S PA + QP ++     +     F +   
Sbjct: 632 TTFSQSLHTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFS---NTSTPTFNIPFG 688

Query: 654 SAATSPT------------GSSHGTPTHQSKPQTLDPFADLGTLGSSSFASKPTTP 697
           S+A SP             G++ G P   +KP     F    T G+S+  +   TP
Sbjct: 689 SSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALAPSFGSSFTFGNSAAPAAAPTP 744


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.132    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,436,203
Number of Sequences: 37866
Number of extensions: 2452258
Number of successful extensions: 10807
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 66
Number of HSP's successfully gapped in prelim test: 596
Number of HSP's that attempted gapping in prelim test: 8964
Number of HSP's gapped (non-prelim): 2020
length of query: 913
length of database: 18,247,518
effective HSP length: 111
effective length of query: 802
effective length of database: 14,044,392
effective search space: 11263602384
effective search space used: 11263602384
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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