BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens] (842 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens] 1647 0.0 gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo sapi... 1563 0.0 gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens] 1361 0.0 gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo sapi... 1358 0.0 gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo sapi... 1261 0.0 gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens] 1259 0.0 gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo sapi... 1238 0.0 gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens] 1236 0.0 gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo sapi... 1201 0.0 gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo sap... 1200 0.0 gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo sapi... 1200 0.0 gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens] 1199 0.0 gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo sapi... 1193 0.0 gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens] 1192 0.0 gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo sap... 1191 0.0 gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo sapi... 1185 0.0 gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens] 1184 0.0 gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens] 1181 0.0 gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo sapi... 1180 0.0 gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapi... 1178 0.0 gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo sapi... 1174 0.0 gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens] 1170 0.0 gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo sap... 1160 0.0 gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo sapi... 1157 0.0 gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo sap... 1150 0.0 gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo sapi... 1150 0.0 gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo sap... 792 0.0 gi|14165402 protocadherin alpha 1 isoform 3 precursor [Homo sapi... 791 0.0 gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo sapi... 781 0.0 gi|14277677 protocadherin gamma subfamily C, 3 isoform 2 precurs... 593 e-169 >gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens] Length = 842 Score = 1647 bits (4264), Expect = 0.0 Identities = 842/842 (100%), Positives = 842/842 (100%) Query: 1 MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60 MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV Sbjct: 1 MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD Sbjct: 61 PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 Query: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL Sbjct: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180 Query: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP Sbjct: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240 Query: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG Sbjct: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300 Query: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK Sbjct: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360 Query: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA Sbjct: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600 Query: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT Sbjct: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV Sbjct: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720 Query: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA Sbjct: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780 Query: 781 GSTERTGEPSASSDSTGKVGFSSILFIYIIFFLERYYRLLPGAVQIVLFIFLEIQQIFFL 840 GSTERTGEPSASSDSTGKVGFSSILFIYIIFFLERYYRLLPGAVQIVLFIFLEIQQIFFL Sbjct: 781 GSTERTGEPSASSDSTGKVGFSSILFIYIIFFLERYYRLLPGAVQIVLFIFLEIQQIFFL 840 Query: 841 IK 842 IK Sbjct: 841 IK 842 >gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1563 bits (4048), Expect = 0.0 Identities = 798/798 (100%), Positives = 798/798 (100%) Query: 1 MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60 MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV Sbjct: 1 MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD Sbjct: 61 PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 Query: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL Sbjct: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180 Query: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP Sbjct: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240 Query: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG Sbjct: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300 Query: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK Sbjct: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360 Query: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA Sbjct: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600 Query: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT Sbjct: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV Sbjct: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720 Query: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA Sbjct: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780 Query: 781 GSTERTGEPSASSDSTGK 798 GSTERTGEPSASSDSTGK Sbjct: 781 GSTERTGEPSASSDSTGK 798 >gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens] Length = 937 Score = 1361 bits (3522), Expect = 0.0 Identities = 697/783 (89%), Positives = 724/783 (92%) Query: 8 DPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLD 67 DP G+ LLL ++ILA W G GQLHYSVPEEA+HG FVGRIAQDLGLELAELVPRLF+ Sbjct: 8 DPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAV 67 Query: 68 SKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIN 127 K RGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIV+RPLQVFHVDVEVKDIN Sbjct: 68 CKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDIN 127 Query: 128 DNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQ 187 DNPPVFPATQ+NLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQ Sbjct: 128 DNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQ 187 Query: 188 QVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLY 247 QVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLY Sbjct: 188 QVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLY 247 Query: 248 TVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGH 307 TVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGH Sbjct: 248 TVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGH 307 Query: 308 MDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGT 367 MDFEESRAHKIPVEAVDKGFPPLAGHCT+LVEVVDVNDNAPQLT+ +LS+P+ EDAQ GT Sbjct: 308 MDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGT 367 Query: 368 VIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTA 427 VI LISV D D NGQVTCSLTP VPFKLVST+KNYYSLVLD ALDRESVSAYELVVTA Sbjct: 368 VITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTA 427 Query: 428 RDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQEN 487 RDGGSPSLWATA VSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQ+N Sbjct: 428 RDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKN 487 Query: 488 ALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS 547 ALVSYSLVE R+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS Sbjct: 488 ALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS 547 Query: 548 NVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWL 607 NVTLQVFVLDENDNAPALL PR+ GT GAV E+V RSVGAG VV KVRAVDADSGYNAWL Sbjct: 548 NVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWL 607 Query: 608 SYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLV 667 SYELQP A ASIPFRVGLYTGEISTTRALDETDAPR RLLVLVKDHGEP+LTATATVLV Sbjct: 608 SYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLV 667 Query: 668 SLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMP 727 SLVESGQAPK+SSRAS+G GPE LVDVNVYLIIAICAVSSLLVLTLLLYT LRCSA Sbjct: 668 SLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPS 727 Query: 728 TEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCAGSTERTG 787 +EG C+ KPTLVCSSAVGSWS+SQQRRQRVCSGEG KTDLMAFSP L ST+ Sbjct: 728 SEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTDNPR 787 Query: 788 EPS 790 +P+ Sbjct: 788 QPN 790 >gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo sapiens] Length = 789 Score = 1358 bits (3515), Expect = 0.0 Identities = 696/777 (89%), Positives = 721/777 (92%) Query: 8 DPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLD 67 DP G+ LLL ++ILA W G GQLHYSVPEEA+HG FVGRIAQDLGLELAELVPRLF+ Sbjct: 8 DPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAV 67 Query: 68 SKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIN 127 K RGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIV+RPLQVFHVDVEVKDIN Sbjct: 68 CKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDIN 127 Query: 128 DNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQ 187 DNPPVFPATQ+NLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQ Sbjct: 128 DNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQ 187 Query: 188 QVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLY 247 QVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLY Sbjct: 188 QVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLY 247 Query: 248 TVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGH 307 TVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGH Sbjct: 248 TVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGH 307 Query: 308 MDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGT 367 MDFEESRAHKIPVEAVDKGFPPLAGHCT+LVEVVDVNDNAPQLT+ +LS+P+ EDAQ GT Sbjct: 308 MDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGT 367 Query: 368 VIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTA 427 VI LISV D D NGQVTCSLTP VPFKLVST+KNYYSLVLD ALDRESVSAYELVVTA Sbjct: 368 VITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTA 427 Query: 428 RDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQEN 487 RDGGSPSLWATA VSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQ+N Sbjct: 428 RDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKN 487 Query: 488 ALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS 547 ALVSYSLVE R+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS Sbjct: 488 ALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS 547 Query: 548 NVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWL 607 NVTLQVFVLDENDNAPALL PR+ GT GAV E+V RSVGAG VV KVRAVDADSGYNAWL Sbjct: 548 NVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWL 607 Query: 608 SYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLV 667 SYELQP A ASIPFRVGLYTGEISTTRALDETDAPR RLLVLVKDHGEP+LTATATVLV Sbjct: 608 SYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLV 667 Query: 668 SLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMP 727 SLVESGQAPK+SSRAS+G GPE LVDVNVYLIIAICAVSSLLVLTLLLYT LRCSA Sbjct: 668 SLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPS 727 Query: 728 TEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCAGSTE 784 +EG C+ KPTLVCSSAVGSWS+SQQRRQRVCSGEG KTDLMAFSP L ST+ Sbjct: 728 SEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTD 784 >gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo sapiens] Length = 798 Score = 1261 bits (3262), Expect = 0.0 Identities = 651/799 (81%), Positives = 701/799 (87%), Gaps = 3/799 (0%) Query: 1 MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60 M +S E + LLL LL+LA W G+GQLHYSV EEA+HGTFVGRIAQDLGLELAELV Sbjct: 1 MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLF++ SKGRG LLEVNLQNGILFVNSRIDREELC RSAECSIHLEVIVDRPLQVFHVD Sbjct: 61 PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD 120 Query: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180 VEV+DINDNPPVFPATQKNL IAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYF L Sbjct: 121 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL 180 Query: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240 + P ++ VK LGL+LRK LDREE PE+ L+LTATDGGKPELTGTVQLLITVLD NDNAP Sbjct: 181 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP 240 Query: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300 FDRT+Y V+L ENV GTLVI NASDLDEGLNGDI+YSFS+D+SP++KSKFH+DP++G Sbjct: 241 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG 300 Query: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360 I V G++DFEES++++I VE +DKG PL+GHC ++VEV D NDN P L K+LS+P++ Sbjct: 301 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR 360 Query: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420 EDA LGTVIALISV D D NG VTCSLT HVPFKLVST+KNYYSLVLD ALDRESVSA Sbjct: 361 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 Query: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PR GT GAVSE+V SVG G VV KVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660 SGYNAWLSYELQP T A IPFRVGLYTGEISTTRALDETDAPR RLLVLVKDHGEPALT Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720 ATATVLVSLVESGQAPK+SSRA VGA GP+ LVDVNVYLIIAICAVSSLLVLTLLLYT Sbjct: 661 ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780 LRCSA+PTEG CAPGKPTLVCSSAVGSWSYSQQRR RVCSGEG KTDLMAFSP L Sbjct: 721 LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSL---P 777 Query: 781 GSTERTGEPSASSDSTGKV 799 S +R + + +S KV Sbjct: 778 DSRDREDQLQTTEESFAKV 796 >gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens] Length = 947 Score = 1259 bits (3258), Expect = 0.0 Identities = 650/798 (81%), Positives = 700/798 (87%), Gaps = 3/798 (0%) Query: 1 MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60 M +S E + LLL LL+LA W G+GQLHYSV EEA+HGTFVGRIAQDLGLELAELV Sbjct: 1 MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLF++ SKGRG LLEVNLQNGILFVNSRIDREELC RSAECSIHLEVIVDRPLQVFHVD Sbjct: 61 PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD 120 Query: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180 VEV+DINDNPPVFPATQKNL IAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYF L Sbjct: 121 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL 180 Query: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240 + P ++ VK LGL+LRK LDREE PE+ L+LTATDGGKPELTGTVQLLITVLD NDNAP Sbjct: 181 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP 240 Query: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300 FDRT+Y V+L ENV GTLVI NASDLDEGLNGDI+YSFS+D+SP++KSKFH+DP++G Sbjct: 241 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG 300 Query: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360 I V G++DFEES++++I VE +DKG PL+GHC ++VEV D NDN P L K+LS+P++ Sbjct: 301 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR 360 Query: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420 EDA LGTVIALISV D D NG VTCSLT HVPFKLVST+KNYYSLVLD ALDRESVSA Sbjct: 361 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 Query: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PR GT GAVSE+V SVG G VV KVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660 SGYNAWLSYELQP T A IPFRVGLYTGEISTTRALDETDAPR RLLVLVKDHGEPALT Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720 ATATVLVSLVESGQAPK+SSRA VGA GP+ LVDVNVYLIIAICAVSSLLVLTLLLYT Sbjct: 661 ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780 LRCSA+PTEG CAPGKPTLVCSSAVGSWSYSQQRR RVCSGEG KTDLMAFSP L Sbjct: 721 LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSL---P 777 Query: 781 GSTERTGEPSASSDSTGK 798 S +R + + +S K Sbjct: 778 DSRDREDQLQTTEESFAK 795 >gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo sapiens] Length = 824 Score = 1238 bits (3202), Expect = 0.0 Identities = 635/806 (78%), Positives = 701/806 (86%) Query: 1 MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60 ML+S R DP Q LLLSLL+LA VGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV Sbjct: 1 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLF++ SK GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+ Sbjct: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 Query: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180 VEVKDINDN PVFP KNLFI+ESR SRF LEGASDADIG N+LLTY L EYF L Sbjct: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180 Query: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240 DV +++++K LGLVL+K L+RE+TP+ +LL+TA DGGKPELTGT QL ITVLD NDNAP Sbjct: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240 Query: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300 F+RT+Y V+L EN GTLV+ NA+DLDEG+N DI YSF++D+S DI SKFH+DP++G Sbjct: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300 Query: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360 I+V G++DFEES++++I VEA DKG PP++ HCT+L+E+VD+NDN P+L I++LS+PV Sbjct: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360 Query: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420 ED+ L TVIALISV D D+ NGQVTCSLTPHVPFKLVST+KNYYSLVLD LDRESVSA Sbjct: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATA VSVEVADVNDNAPAF+QSEYTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PR+ G GAVSE+V RSVGAG VV KVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660 SGYNAWLSYELQP T A IPFRVGLYTGEISTTRALDE DAPR RLLVLVKDHGEP+LT Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660 Query: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720 ATATVLVSLVESGQAPK+SS+AS GATGPE LVDVNVYLI+AICAVSSLLVLTLLLYT Sbjct: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780 LRCSA PTEG+C PGKPTLVCSSAVGSWSYSQQR+QRVCSGEG KTDLMAFSP L PC Sbjct: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780 Query: 781 GSTERTGEPSASSDSTGKVGFSSILF 806 S +R + D + KV + F Sbjct: 781 ISRDREEKQDVDVDLSAKVSNFYLFF 806 >gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1236 bits (3197), Expect = 0.0 Identities = 633/798 (79%), Positives = 698/798 (87%) Query: 1 MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60 ML+S R DP Q LLLSLL+LA VGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV Sbjct: 1 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLF++ SK GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+ Sbjct: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 Query: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180 VEVKDINDN PVFP KNLFI+ESR SRF LEGASDADIG N+LLTY L EYF L Sbjct: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180 Query: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240 DV +++++K LGLVL+K L+RE+TP+ +LL+TA DGGKPELTGT QL ITVLD NDNAP Sbjct: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240 Query: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300 F+RT+Y V+L EN GTLV+ NA+DLDEG+N DI YSF++D+S DI SKFH+DP++G Sbjct: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300 Query: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360 I+V G++DFEES++++I VEA DKG PP++ HCT+L+E+VD+NDN P+L I++LS+PV Sbjct: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360 Query: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420 ED+ L TVIALISV D D+ NGQVTCSLTPHVPFKLVST+KNYYSLVLD LDRESVSA Sbjct: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATA VSVEVADVNDNAPAF+QSEYTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PR+ G GAVSE+V RSVGAG VV KVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660 SGYNAWLSYELQP T A IPFRVGLYTGEISTTRALDE DAPR RLLVLVKDHGEP+LT Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660 Query: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720 ATATVLVSLVESGQAPK+SS+AS GATGPE LVDVNVYLI+AICAVSSLLVLTLLLYT Sbjct: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780 LRCSA PTEG+C PGKPTLVCSSAVGSWSYSQQR+QRVCSGEG KTDLMAFSP L PC Sbjct: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780 Query: 781 GSTERTGEPSASSDSTGK 798 S +R + D + K Sbjct: 781 ISRDREEKQDVDVDLSAK 798 >gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo sapiens] Length = 807 Score = 1201 bits (3106), Expect = 0.0 Identities = 615/799 (76%), Positives = 686/799 (85%) Query: 1 MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60 M++S RG + LLL LL+LA W VGSGQLHYS+PEEA+HGTFVGR+AQDLGLELAELV Sbjct: 1 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60 Query: 61 PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLF++ SK DLLEVNLQNGILFVNSRIDREELC SAECSIHLE+I DRPLQVFHV+ Sbjct: 61 PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120 Query: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180 V+VKDINDNPPVF ++ +FI ESR L+SRFP+EGA+DADIG NALLTY LSP++YF L Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180 Query: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240 DV S++ K L L LRK LDREETPELHLLLTATDGGKPEL GTV+LLITVLD NDNAP Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240 Query: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300 +FD+ +Y V L E + GTLV NASD DEG+NG++++SF S +S DI+ KF +D SG Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300 Query: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360 I +I +D+EE+++++I V+AVDKG PP++ HC +LV+V+DVNDNAP+L + +L +P++ Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360 Query: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420 EDA L TVIALI+V D D+ ANGQVTCSL PHVPFKLVST+KNYYSLVLD ALDRES+S Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420 Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERR+GER+LS+YVSVHAESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PR+ GT GAVSE+V R VGAG VV KVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660 SGYNAWLSYELQP A IPFRVGLYTGEISTTR LDE D R RLLVLVKDHGEPALT Sbjct: 601 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720 ATATVLVSLVESGQAPK+SSRASVG GPE LVDVNVYLIIAICAVSSLLVLTLLLYT Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780 LRCS PTEG PGKPTLVCSSA+GSWS SQQRRQRVCS EG KTDLMAFSPGLSP Sbjct: 721 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL 780 Query: 781 GSTERTGEPSASSDSTGKV 799 ++ER +P A+ D +G V Sbjct: 781 NTSERNEQPEANLDLSGNV 799 >gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo sapiens] Length = 807 Score = 1200 bits (3105), Expect = 0.0 Identities = 618/799 (77%), Positives = 678/799 (84%) Query: 1 MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60 ML S +G P + LLL LLILA W GSGQLHYSVPEEA+HGTFVGRIAQDLGLELAELV Sbjct: 1 MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLF++ SK GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+ Sbjct: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 Query: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180 V+V+DINDNPP+FP ++K + IAESRP ++RFPL+GASDADIG N+ LTYRL PN+YF L Sbjct: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180 Query: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240 D S +Q+ L LVLRK LDREE E LLLTA+DGGKPELTGTVQLLIT+LD NDNAP Sbjct: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240 Query: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300 F +++Y V + EN GTLVI NA+D D+G NGDI+YSF V P + F ++P +G Sbjct: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300 Query: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360 I G +DFEE + ++I VEAVDKG P+AGHCTLLVEV+DVNDNAP++TI +LS+P++ Sbjct: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360 Query: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420 ED Q +IALISV D D+ +NGQVTC+LTPHVPFKLVSTYKNYYSLVLD ALDRESVSA Sbjct: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATA VSV VADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA+ Sbjct: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480 Query: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD+ Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALLTP G VSE++ RSVGAG VV KVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660 SGYNAWLSYELQ A IPFRVGLYTGEISTTR LDE DAP RLLVLVKDHGEPALT Sbjct: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720 ATATVL+SLVESGQAP++SSRAS GA GPE LVDVNVYLIIAICAVSSLLVLTLLLYT Sbjct: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780 LRCSA PTEG CAPGKPTLVCSSA GSWSYSQQRR RVCSGEG KTDLMAFSP L PC Sbjct: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL 780 Query: 781 GSTERTGEPSASSDSTGKV 799 GS E TG+ S+ +V Sbjct: 781 GSAEGTGQREEDSECLKEV 799 >gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1200 bits (3104), Expect = 0.0 Identities = 617/794 (77%), Positives = 676/794 (85%) Query: 1 MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60 ML S +G P + LLL LLILA W GSGQLHYSVPEEA+HGTFVGRIAQDLGLELAELV Sbjct: 1 MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLF++ SK GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+ Sbjct: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 Query: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180 V+V+DINDNPP+FP ++K + IAESRP ++RFPL+GASDADIG N+ LTYRL PN+YF L Sbjct: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180 Query: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240 D S +Q+ L LVLRK LDREE E LLLTA+DGGKPELTGTVQLLIT+LD NDNAP Sbjct: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240 Query: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300 F +++Y V + EN GTLVI NA+D D+G NGDI+YSF V P + F ++P +G Sbjct: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300 Query: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360 I G +DFEE + ++I VEAVDKG P+AGHCTLLVEV+DVNDNAP++TI +LS+P++ Sbjct: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360 Query: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420 ED Q +IALISV D D+ +NGQVTC+LTPHVPFKLVSTYKNYYSLVLD ALDRESVSA Sbjct: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATA VSV VADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA+ Sbjct: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480 Query: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD+ Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALLTP G VSE++ RSVGAG VV KVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660 SGYNAWLSYELQ A IPFRVGLYTGEISTTR LDE DAP RLLVLVKDHGEPALT Sbjct: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720 ATATVL+SLVESGQAP++SSRAS GA GPE LVDVNVYLIIAICAVSSLLVLTLLLYT Sbjct: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780 LRCSA PTEG CAPGKPTLVCSSA GSWSYSQQRR RVCSGEG KTDLMAFSP L PC Sbjct: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL 780 Query: 781 GSTERTGEPSASSD 794 GS E TG+ S+ Sbjct: 781 GSAEGTGQREEDSE 794 >gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1199 bits (3102), Expect = 0.0 Identities = 614/797 (77%), Positives = 685/797 (85%) Query: 1 MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60 M++S RG + LLL LL+LA W VGSGQLHYS+PEEA+HGTFVGR+AQDLGLELAELV Sbjct: 1 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60 Query: 61 PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLF++ SK DLLEVNLQNGILFVNSRIDREELC SAECSIHLE+I DRPLQVFHV+ Sbjct: 61 PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120 Query: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180 V+VKDINDNPPVF ++ +FI ESR L+SRFP+EGA+DADIG NALLTY LSP++YF L Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180 Query: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240 DV S++ K L L LRK LDREETPELHLLLTATDGGKPEL GTV+LLITVLD NDNAP Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240 Query: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300 +FD+ +Y V L E + GTLV NASD DEG+NG++++SF S +S DI+ KF +D SG Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300 Query: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360 I +I +D+EE+++++I V+AVDKG PP++ HC +LV+V+DVNDNAP+L + +L +P++ Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360 Query: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420 EDA L TVIALI+V D D+ ANGQVTCSL PHVPFKLVST+KNYYSLVLD ALDRES+S Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420 Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERR+GER+LS+YVSVHAESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PR+ GT GAVSE+V R VGAG VV KVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660 SGYNAWLSYELQP A IPFRVGLYTGEISTTR LDE D R RLLVLVKDHGEPALT Sbjct: 601 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720 ATATVLVSLVESGQAPK+SSRASVG GPE LVDVNVYLIIAICAVSSLLVLTLLLYT Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780 LRCS PTEG PGKPTLVCSSA+GSWS SQQRRQRVCS EG KTDLMAFSPGLSP Sbjct: 721 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL 780 Query: 781 GSTERTGEPSASSDSTG 797 ++ER +P A+ D +G Sbjct: 781 NTSERNEQPEANLDLSG 797 >gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo sapiens] Length = 803 Score = 1193 bits (3086), Expect = 0.0 Identities = 610/788 (77%), Positives = 673/788 (85%) Query: 12 QPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGR 71 Q LLL LL+LA W VGSGQLHYSVPEEA+HGTFVGRIAQDLGLELAELVPRLF++ SK R Sbjct: 12 QCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDR 71 Query: 72 GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPP 131 DLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEV+DINDNPP Sbjct: 72 EDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPP 131 Query: 132 VFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKP 191 +FP ++ + I ESR DS FPLEGASDAD+G N++LTY+LS +EYF LDV ++ K Sbjct: 132 LFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQ 191 Query: 192 LGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKL 251 +GL+L+K LDREE P +L LTATDGGKPELTGTVQLL+TVLD NDNAP F+++ Y V++ Sbjct: 192 IGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRI 251 Query: 252 PENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFE 311 EN GT VI NASD DEG NG I YSF+S V+ + F +D +G I + G++DFE Sbjct: 252 FENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFE 311 Query: 312 ESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIAL 371 + +KI ++A DKG PP+AGHCT+LV ++D NDN P++ + +LS+PV+EDAQ GTVIAL Sbjct: 312 QENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIAL 371 Query: 372 ISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGG 431 ISV DLD+ ANGQV CSLTPHVPFKLVST+KNYYSLVLD ALDRESVSAYELVVTARDGG Sbjct: 372 ISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG 431 Query: 432 SPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVS 491 SPSLWATA +SVEVAD+NDNAPAFAQ EYTVFVKENNPPGCHIFTVSARDADAQENALVS Sbjct: 432 SPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVS 491 Query: 492 YSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL 551 YSLVERR+GER+LSSY+SVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL Sbjct: 492 YSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL 551 Query: 552 QVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLSYEL 611 QVFVLDENDNAPALL PR+ GT GAVSE+V RS+GAG VV KVRAVDADSGYNAWLSYEL Sbjct: 552 QVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSYEL 611 Query: 612 QPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVSLVE 671 QP +SA PFRVGLYTGEISTTR LDE D+PR RLLVLVKDHGEPALTATATVLVSLVE Sbjct: 612 QPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVE 671 Query: 672 SGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMPTEGE 731 SGQAPK+SSRASVGA GPE LVDVNVYLIIAICAVSSLLVLTLLLYT LRCSA PTEG Sbjct: 672 SGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGA 731 Query: 732 CAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCAGSTERTGEPSA 791 C KPTLVCSSAVGSWSYSQQRRQRVCSGEG K DLMAFSP LSPC + Sbjct: 732 CTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAENQDL 791 Query: 792 SSDSTGKV 799 + D KV Sbjct: 792 NEDHDAKV 799 >gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1192 bits (3083), Expect = 0.0 Identities = 607/768 (79%), Positives = 668/768 (86%) Query: 12 QPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGR 71 Q LLL LL+LA W VGSGQLHYSVPEEA+HGTFVGRIAQDLGLELAELVPRLF++ SK R Sbjct: 12 QCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDR 71 Query: 72 GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPP 131 DLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEV+DINDNPP Sbjct: 72 EDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPP 131 Query: 132 VFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKP 191 +FP ++ + I ESR DS FPLEGASDAD+G N++LTY+LS +EYF LDV ++ K Sbjct: 132 LFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQ 191 Query: 192 LGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKL 251 +GL+L+K LDREE P +L LTATDGGKPELTGTVQLL+TVLD NDNAP F+++ Y V++ Sbjct: 192 IGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRI 251 Query: 252 PENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFE 311 EN GT VI NASD DEG NG I YSF+S V+ + F +D +G I + G++DFE Sbjct: 252 FENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFE 311 Query: 312 ESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIAL 371 + +KI ++A DKG PP+AGHCT+LV ++D NDN P++ + +LS+PV+EDAQ GTVIAL Sbjct: 312 QENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIAL 371 Query: 372 ISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGG 431 ISV DLD+ ANGQV CSLTPHVPFKLVST+KNYYSLVLD ALDRESVSAYELVVTARDGG Sbjct: 372 ISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG 431 Query: 432 SPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVS 491 SPSLWATA +SVEVAD+NDNAPAFAQ EYTVFVKENNPPGCHIFTVSARDADAQENALVS Sbjct: 432 SPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVS 491 Query: 492 YSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL 551 YSLVERR+GER+LSSY+SVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL Sbjct: 492 YSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL 551 Query: 552 QVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLSYEL 611 QVFVLDENDNAPALL PR+ GT GAVSE+V RS+GAG VV KVRAVDADSGYNAWLSYEL Sbjct: 552 QVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSYEL 611 Query: 612 QPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVSLVE 671 QP +SA PFRVGLYTGEISTTR LDE D+PR RLLVLVKDHGEPALTATATVLVSLVE Sbjct: 612 QPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVE 671 Query: 672 SGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMPTEGE 731 SGQAPK+SSRASVGA GPE LVDVNVYLIIAICAVSSLLVLTLLLYT LRCSA PTEG Sbjct: 672 SGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGA 731 Query: 732 CAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPC 779 C KPTLVCSSAVGSWSYSQQRRQRVCSGEG K DLMAFSP LSPC Sbjct: 732 CTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPC 779 >gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo sapiens] Length = 844 Score = 1191 bits (3081), Expect = 0.0 Identities = 628/821 (76%), Positives = 683/821 (83%), Gaps = 5/821 (0%) Query: 12 QPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGR 71 Q LLLSLL+LA W VGSGQLHYSV EEA HGTFVGRIAQDLGLELAELV RLF++ SK Sbjct: 11 QCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASKRH 70 Query: 72 GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPP 131 GDLLEVNLQNGILFVNSRIDREELCGRS ECSIHLEVIVDRPLQVFHVDVEVKDINDNPP Sbjct: 71 GDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDNPP 130 Query: 132 VFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKP 191 F T++ L I ESR LDSRFPLEGASDAD+GENALLTY+LSPNEYF LD+ + K Sbjct: 131 RFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKDKF 190 Query: 192 LGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKL 251 LVLRKLLDREE P+L LLLTATDGGKPE TG+V LLI VLD NDNAP+FDR +Y VK+ Sbjct: 191 PVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEVKM 250 Query: 252 PENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFE 311 EN TLVI NASD DEG+N +++YSFSS V P I+ KF ++ +G I V +DFE Sbjct: 251 YENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAIDFE 310 Query: 312 ESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIAL 371 +S ++I V+ DKG PP+ GHCT+LVE++D NDN+P++ + +LS+PVKEDAQ+GTVIAL Sbjct: 311 DSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVIAL 370 Query: 372 ISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGG 431 ISV D D+ ANGQVTCSLTPHVPFKLVSTYKNYYSLVLD ALDRE VSAYELVVTARDGG Sbjct: 371 ISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARDGG 430 Query: 432 SPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVS 491 SP LWATA VSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSA DADAQENALVS Sbjct: 431 SPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENALVS 490 Query: 492 YSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL 551 YSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD GVPPLGSN+TL Sbjct: 491 YSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNLTL 550 Query: 552 QVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLSYEL 611 QVFVLDENDNAPALL GAVSE+VLRSV AG VV KVRAVDADSGYNAWLSYEL Sbjct: 551 QVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSYEL 610 Query: 612 QPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVSLVE 671 Q A IPFRVGLYTGEISTTRALDETD+PRQRLLVLVKDHGEP+LTATATVLVSLVE Sbjct: 611 QSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSLVE 670 Query: 672 SGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMPTEGE 731 QAPK+SSRASVG PEV LVDVNVYLIIAICAVSSLLVLTLLLYT LRCSA PTEG Sbjct: 671 GSQAPKASSRASVG-VAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPTEGA 729 Query: 732 CAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCAGSTERTGEPSA 791 C P KPTLVCSSAVGSWSYSQQRRQRVCSGEG K DLMAFSP L PC + S Sbjct: 730 CGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCPMVDVDGEDQSI 789 Query: 792 SSDSTGKVGFSSILFIYIIFFLERY--YRLLPGAVQIVLFI 830 D + KVG+ +FI+++ F+ YR+ Q + F+ Sbjct: 790 GGDHSRKVGY--YVFIFLLCFMNNIFSYRIFSNMYQNISFL 828 >gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo sapiens] Length = 814 Score = 1185 bits (3066), Expect = 0.0 Identities = 612/799 (76%), Positives = 673/799 (84%) Query: 1 MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60 M Y RG+ LLL LL+LA W VGSGQLHYSVPEEA+HGTFVGRIAQDLGLELAELV Sbjct: 1 MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLF++ SK DLLEV+LQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD Sbjct: 61 PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 Query: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180 VEVKD+NDNPPVF + LF++ESR DSRFPLEGASDAD+G N++LTYRLS ++YF L Sbjct: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180 Query: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240 DV + N + K + LVLRK LDRE+ P HL LTATDGGKPELTGTVQLL+TVLD NDNAP Sbjct: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 Query: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300 F+++ Y V++ EN GT VI NASD DEG NG I YSF+S V + F +D +G Sbjct: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300 Query: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360 I + G++DFE+ +KI ++A DKG PP+AGHCT+LV ++D NDN P++ + +LS+PV+ Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 Query: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420 EDAQ GTVIALISV DLD+ ANGQVTCSL PHVPFKLVST+KNYYSLVLD ALDRE VSA Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420 Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATA +SVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERR+GERSLSSY+SVH ESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PR+ GT GA S++V RSVGAG VV KVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660 SGYNAWLSYELQP +S IPFRVGLYTGEISTTR LDE D+PR RLLVLVKDHGEPALT Sbjct: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720 ATATVLVSLVESGQAPK+SSR S G GPE LVDVNVYLIIAICAVSSLLVLTLLLYT Sbjct: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780 LRCSA+PTEG C GKPTLVCSSAVGSWSYSQQ+ QRVCSGEG KTDLMAFSP L P Sbjct: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL 780 Query: 781 GSTERTGEPSASSDSTGKV 799 GS + E + D KV Sbjct: 781 GSVDVGEEQDLNVDHGLKV 799 >gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1184 bits (3064), Expect = 0.0 Identities = 610/794 (76%), Positives = 671/794 (84%) Query: 1 MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60 M Y RG+ LLL LL+LA W VGSGQLHYSVPEEA+HGTFVGRIAQDLGLELAELV Sbjct: 1 MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLF++ SK DLLEV+LQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD Sbjct: 61 PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 Query: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180 VEVKD+NDNPPVF + LF++ESR DSRFPLEGASDAD+G N++LTYRLS ++YF L Sbjct: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180 Query: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240 DV + N + K + LVLRK LDRE+ P HL LTATDGGKPELTGTVQLL+TVLD NDNAP Sbjct: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 Query: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300 F+++ Y V++ EN GT VI NASD DEG NG I YSF+S V + F +D +G Sbjct: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300 Query: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360 I + G++DFE+ +KI ++A DKG PP+AGHCT+LV ++D NDN P++ + +LS+PV+ Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 Query: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420 EDAQ GTVIALISV DLD+ ANGQVTCSL PHVPFKLVST+KNYYSLVLD ALDRE VSA Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420 Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATA +SVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERR+GERSLSSY+SVH ESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PR+ GT GA S++V RSVGAG VV KVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660 SGYNAWLSYELQP +S IPFRVGLYTGEISTTR LDE D+PR RLLVLVKDHGEPALT Sbjct: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720 ATATVLVSLVESGQAPK+SSR S G GPE LVDVNVYLIIAICAVSSLLVLTLLLYT Sbjct: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780 LRCSA+PTEG C GKPTLVCSSAVGSWSYSQQ+ QRVCSGEG KTDLMAFSP L P Sbjct: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL 780 Query: 781 GSTERTGEPSASSD 794 GS + E + D Sbjct: 781 GSVDVGEEQDLNVD 794 >gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens] Length = 936 Score = 1181 bits (3055), Expect = 0.0 Identities = 613/790 (77%), Positives = 671/790 (84%), Gaps = 1/790 (0%) Query: 1 MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60 M+YS RG G LLL L+LA W GSGQLHYS+PEEA+HGTFVGRIAQDLGLELAELV Sbjct: 1 MVYSRRGSL-GSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59 Query: 61 PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLF++ SKGRGDLLEVNLQNGILFVNSRIDREELC R AECSIHLEVIVDRPLQVFHV+ Sbjct: 60 PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119 Query: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180 V VKDINDNPP F ++ LFI ESR DSRFPLEGASD DIG NA L YRL+PNEYF L Sbjct: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179 Query: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240 DV T+ ++ L LVLRK LDREET E LL+ ATDGGKPELTGTVQLLI VLD NDNAP Sbjct: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239 Query: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300 FD+++Y V+L EN GTLVI NASD DEG+N +I+Y FS+ V D+KSKF ++ +G Sbjct: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299 Query: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360 I V G +D+E+ +++I ++A+DK PL+GHC ++V+++DVNDN P++ I TL +PVK Sbjct: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359 Query: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420 EDA L TVIALISV D D+ ANGQVTCSL PHVPFKLVST+KNYYSLVLD ALDRESVS Sbjct: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419 Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQ +YTVFVKENNPPGCHIFTVSAR Sbjct: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479 Query: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERR+GER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDA Sbjct: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PR+ GT GAVSE+V RSVGAG VV KVRAVD D Sbjct: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599 Query: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660 SGYNAWLSYELQP SA IPFRVGLYTGEISTTR+LDET+APR RLLVLVKDHGEP LT Sbjct: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659 Query: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720 ATATVLVSLVESGQAPK+SSRAS GA GPE LVDVNVYLIIAICAVSSLLVLTLLLYT Sbjct: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719 Query: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780 LRCSA PTE C GKPTL+CSSAVGSWSYSQQRRQRVCSGE KTDLMAFSP L Sbjct: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGP 779 Query: 781 GSTERTGEPS 790 ST+ +P+ Sbjct: 780 TSTDNPRQPN 789 >gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo sapiens] Length = 948 Score = 1180 bits (3052), Expect = 0.0 Identities = 616/768 (80%), Positives = 660/768 (85%), Gaps = 1/768 (0%) Query: 12 QPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGR 71 Q LLLSLL+LA W VGSGQLHYSV EEA HGTFVGRIAQDLGLELAELV RLF++ SK Sbjct: 11 QCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASKRH 70 Query: 72 GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPP 131 GDLLEVNLQNGILFVNSRIDREELCGRS ECSIHLEVIVDRPLQVFHVDVEVKDINDNPP Sbjct: 71 GDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDNPP 130 Query: 132 VFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKP 191 F T++ L I ESR LDSRFPLEGASDAD+GENALLTY+LSPNEYF LD+ + K Sbjct: 131 RFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKDKF 190 Query: 192 LGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKL 251 LVLRKLLDREE P+L LLLTATDGGKPE TG+V LLI VLD NDNAP+FDR +Y VK+ Sbjct: 191 PVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEVKM 250 Query: 252 PENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFE 311 EN TLVI NASD DEG+N +++YSFSS V P I+ KF ++ +G I V +DFE Sbjct: 251 YENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAIDFE 310 Query: 312 ESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIAL 371 +S ++I V+ DKG PP+ GHCT+LVE++D NDN+P++ + +LS+PVKEDAQ+GTVIAL Sbjct: 311 DSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVIAL 370 Query: 372 ISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGG 431 ISV D D+ ANGQVTCSLTPHVPFKLVSTYKNYYSLVLD ALDRE VSAYELVVTARDGG Sbjct: 371 ISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARDGG 430 Query: 432 SPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVS 491 SP LWATA VSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSA DADAQENALVS Sbjct: 431 SPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENALVS 490 Query: 492 YSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL 551 YSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD GVPPLGSN+TL Sbjct: 491 YSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNLTL 550 Query: 552 QVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLSYEL 611 QVFVLDENDNAPALL GAVSE+VLRSV AG VV KVRAVDADSGYNAWLSYEL Sbjct: 551 QVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSYEL 610 Query: 612 QPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVSLVE 671 Q A IPFRVGLYTGEISTTRALDETD+PRQRLLVLVKDHGEP+LTATATVLVSLVE Sbjct: 611 QSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSLVE 670 Query: 672 SGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMPTEGE 731 QAPK+SSRASVG PEV LVDVNVYLIIAICAVSSLLVLTLLLYT LRCSA PTEG Sbjct: 671 GSQAPKASSRASVG-VAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPTEGA 729 Query: 732 CAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPC 779 C P KPTLVCSSAVGSWSYSQQRRQRVCSGEG K DLMAFSP L PC Sbjct: 730 CGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPC 777 >gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapiens] Length = 816 Score = 1178 bits (3048), Expect = 0.0 Identities = 612/784 (78%), Positives = 668/784 (85%), Gaps = 1/784 (0%) Query: 1 MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60 M+YS RG G LLL L+LA W GSGQLHYS+PEEA+HGTFVGRIAQDLGLELAELV Sbjct: 1 MVYSRRGSL-GSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59 Query: 61 PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLF++ SKGRGDLLEVNLQNGILFVNSRIDREELC R AECSIHLEVIVDRPLQVFHV+ Sbjct: 60 PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119 Query: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180 V VKDINDNPP F ++ LFI ESR DSRFPLEGASD DIG NA L YRL+PNEYF L Sbjct: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179 Query: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240 DV T+ ++ L LVLRK LDREET E LL+ ATDGGKPELTGTVQLLI VLD NDNAP Sbjct: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239 Query: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300 FD+++Y V+L EN GTLVI NASD DEG+N +I+Y FS+ V D+KSKF ++ +G Sbjct: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299 Query: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360 I V G +D+E+ +++I ++A+DK PL+GHC ++V+++DVNDN P++ I TL +PVK Sbjct: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359 Query: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420 EDA L TVIALISV D D+ ANGQVTCSL PHVPFKLVST+KNYYSLVLD ALDRESVS Sbjct: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419 Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQ +YTVFVKENNPPGCHIFTVSAR Sbjct: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479 Query: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERR+GER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDA Sbjct: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PR+ GT GAVSE+V RSVGAG VV KVRAVD D Sbjct: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599 Query: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660 SGYNAWLSYELQP SA IPFRVGLYTGEISTTR+LDET+APR RLLVLVKDHGEP LT Sbjct: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659 Query: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720 ATATVLVSLVESGQAPK+SSRAS GA GPE LVDVNVYLIIAICAVSSLLVLTLLLYT Sbjct: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719 Query: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780 LRCSA PTE C GKPTL+CSSAVGSWSYSQQRRQRVCSGE KTDLMAFSP L Sbjct: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGP 779 Query: 781 GSTE 784 ST+ Sbjct: 780 TSTD 783 >gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo sapiens] Length = 824 Score = 1174 bits (3037), Expect = 0.0 Identities = 609/805 (75%), Positives = 679/805 (84%), Gaps = 2/805 (0%) Query: 15 LLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGRGDL 74 LLSLL+LA W VGSGQL YSVPEEA+HGTFVGRIAQDLGLEL ELVPRLF++ SK GDL Sbjct: 15 LLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDL 74 Query: 75 LEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPPVFP 134 LEVNLQNGILFVNSRIDREELCGRSAECSIH+EVIVDRPLQVFHV+VEVKDINDNPP+FP Sbjct: 75 LEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDNPPIFP 134 Query: 135 ATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLGL 194 T K + ESR LDSRFPLEGASDADIG NALL+Y+LS +E+FFLD+ +++ + L L Sbjct: 135 MTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELSESLSL 194 Query: 195 VLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPEN 254 VL K LDREET E++LLL ATDGGKPELTGTVQ+LI VLD NDN P F +++Y VKL EN Sbjct: 195 VLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLEN 254 Query: 255 VSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEESR 314 + GTLV+ NASD DEG N +I+YS SDVS I++KF +DP+SG I G +D+EE++ Sbjct: 255 TANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAK 314 Query: 315 AHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIALISV 374 +++I V A DKG P ++GHC + +++VD+NDN P+++I +LS+P+ E+A LGTVIALI+V Sbjct: 315 SYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITV 374 Query: 375 IDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGGSPS 434 D D+ NG VTCSLTPHVPFKLVST+KNYYSLVLD ALDRESVSAYELVVTARDGGSPS Sbjct: 375 SDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434 Query: 435 LWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSL 494 LWAT VS+EVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQENALVSYSL Sbjct: 435 LWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494 Query: 495 VERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVF 554 VERR+GER+LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLGSNVTLQVF Sbjct: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVF 554 Query: 555 VLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLSYELQPE 614 VLDENDNAPALL PR GAVSE+V SVGAG VV KVRAVDADSGYNAWLSYELQ Sbjct: 555 VLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLG 614 Query: 615 TASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVSLVESGQ 674 T SA IPFRVGLYTGEISTTRALDE D+PR RLLVLVKDHGEPALTATATVLVSLVESGQ Sbjct: 615 TGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674 Query: 675 APKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMPTEGECAP 734 APK+SSRA VGA G E TLVDVNVYLIIAICAVSSLLVLT+LLYT LRCS PTEG AP Sbjct: 675 APKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTEGARAP 734 Query: 735 GKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCAGSTERTGEPSASSD 794 GKPTLVCSSAVGSWSYSQQRRQRVCSGE KTDLMAFSP LS S E + + S+ Sbjct: 735 GKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAEE--KQLSESE 792 Query: 795 STGKVGFSSILFIYIIFFLERYYRL 819 GKV L I +++Y + Sbjct: 793 YVGKVSLLLFLANSKIVLFKKFYMI 817 >gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens] Length = 948 Score = 1170 bits (3026), Expect = 0.0 Identities = 605/784 (77%), Positives = 671/784 (85%), Gaps = 2/784 (0%) Query: 15 LLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGRGDL 74 LLSLL+LA W VGSGQL YSVPEEA+HGTFVGRIAQDLGLEL ELVPRLF++ SK GDL Sbjct: 15 LLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDL 74 Query: 75 LEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPPVFP 134 LEVNLQNGILFVNSRIDREELCGRSAECSIH+EVIVDRPLQVFHV+VEVKDINDNPP+FP Sbjct: 75 LEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDNPPIFP 134 Query: 135 ATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLGL 194 T K + ESR LDSRFPLEGASDADIG NALL+Y+LS +E+FFLD+ +++ + L L Sbjct: 135 MTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELSESLSL 194 Query: 195 VLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPEN 254 VL K LDREET E++LLL ATDGGKPELTGTVQ+LI VLD NDN P F +++Y VKL EN Sbjct: 195 VLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLEN 254 Query: 255 VSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEESR 314 + GTLV+ NASD DEG N +I+YS SDVS I++KF +DP+SG I G +D+EE++ Sbjct: 255 TANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAK 314 Query: 315 AHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIALISV 374 +++I V A DKG P ++GHC + +++VD+NDN P+++I +LS+P+ E+A LGTVIALI+V Sbjct: 315 SYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITV 374 Query: 375 IDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGGSPS 434 D D+ NG VTCSLTPHVPFKLVST+KNYYSLVLD ALDRESVSAYELVVTARDGGSPS Sbjct: 375 SDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434 Query: 435 LWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSL 494 LWAT VS+EVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQENALVSYSL Sbjct: 435 LWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494 Query: 495 VERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVF 554 VERR+GER+LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLGSNVTLQVF Sbjct: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVF 554 Query: 555 VLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLSYELQPE 614 VLDENDNAPALL PR GAVSE+V SVGAG VV KVRAVDADSGYNAWLSYELQ Sbjct: 555 VLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLG 614 Query: 615 TASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVSLVESGQ 674 T SA IPFRVGLYTGEISTTRALDE D+PR RLLVLVKDHGEPALTATATVLVSLVESGQ Sbjct: 615 TGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674 Query: 675 APKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMPTEGECAP 734 APK+SSRA VGA G E TLVDVNVYLIIAICAVSSLLVLT+LLYT LRCS PTEG AP Sbjct: 675 APKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTEGARAP 734 Query: 735 GKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCAGSTERTGEPSASSD 794 GKPTLVCSSAVGSWSYSQQRRQRVCSGE KTDLMAFSP LS S E + + S+ Sbjct: 735 GKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAEE--KQLSESE 792 Query: 795 STGK 798 GK Sbjct: 793 YVGK 796 >gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo sapiens] Length = 810 Score = 1160 bits (3002), Expect = 0.0 Identities = 604/792 (76%), Positives = 668/792 (84%), Gaps = 3/792 (0%) Query: 14 LLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGRGD 73 L L LL+L W VGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLF++ SK GD Sbjct: 14 LQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRVASKTHGD 73 Query: 74 LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPPVF 133 LLEVNLQNGILFVNSRIDREELCG+SAECSIHLEVIVDRPLQVFHV+VEVKDINDNPPVF Sbjct: 74 LLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDINDNPPVF 133 Query: 134 PATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLG 193 ++ L IAES+ DSRFPLEGASDADI ENALLTYRLS NEYF LD PT+ +Q+K L Sbjct: 134 SLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNGKQIKRLS 193 Query: 194 LVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPE 253 L+L+K LDRE+TPEL+LLLTATDGGKPELTGTV+LL+ VLD NDN P FD++ Y V L E Sbjct: 194 LILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSEYKVSLME 253 Query: 254 NVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEES 313 N + TLV+ NA+D DEG+NG++ YS S + P+ + F +D +G + V G +D+EE+ Sbjct: 254 NAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVNGTLDYEEN 312 Query: 314 RAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIALIS 373 + +KI V+A DKG PP+AGHCT+ VE++D NDN+P++ + +LS+PV+EDAQ TVIALIS Sbjct: 313 KFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPSTVIALIS 372 Query: 374 VIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGGSP 433 V D D+ NGQVTCSLTPHVPFKLVST+KNYYSLVLD ALDRE+V AYELVVTARDGGSP Sbjct: 373 VSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVTARDGGSP 432 Query: 434 SLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYS 493 SLWATARVSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSARDADAQENALVSYS Sbjct: 433 SLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYS 492 Query: 494 LVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQV 553 LVERRLG+R+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL SNVTLQV Sbjct: 493 LVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLSSNVTLQV 552 Query: 554 FVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLSYELQP 613 FVLDENDNAPALL + GAV+++V RSVGAG VV KVRAVDADSGYNAWLSYELQP Sbjct: 553 FVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQP 612 Query: 614 ETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVSLVESG 673 + IPFRVGLYTGEISTTRALDE D+PR RLLVLVKDHGEPALTATATVLVSLVESG Sbjct: 613 AAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESG 672 Query: 674 QAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMPTEGECA 733 QAPK+SSR GA PE LVDVNVYLIIAIC VSSLLVLTLLLYT L SA PTEG CA Sbjct: 673 QAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSATPTEGACA 732 Query: 734 PGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCAGSTERTGE-PSAS 792 PGKPTLVCS AVGSWSYSQQRRQRVCS EG KTDLMAFSP L P + E GE Sbjct: 733 PGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSL-PLGLNKEEEGERQEPG 791 Query: 793 SDSTGKVGFSSI 804 S+ G+V F I Sbjct: 792 SNHPGQVSFLQI 803 >gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo sapiens] Length = 949 Score = 1157 bits (2994), Expect = 0.0 Identities = 599/775 (77%), Positives = 661/775 (85%), Gaps = 2/775 (0%) Query: 14 LLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGRGD 73 L L LL+L W VGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLF++ SK GD Sbjct: 14 LQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRVASKTHGD 73 Query: 74 LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPPVF 133 LLEVNLQNGILFVNSRIDREELCG+SAECSIHLEVIVDRPLQVFHV+VEVKDINDNPPVF Sbjct: 74 LLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDINDNPPVF 133 Query: 134 PATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLG 193 ++ L IAES+ DSRFPLEGASDADI ENALLTYRLS NEYF LD PT+ +Q+K L Sbjct: 134 SLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNGKQIKRLS 193 Query: 194 LVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPE 253 L+L+K LDRE+TPEL+LLLTATDGGKPELTGTV+LL+ VLD NDN P FD++ Y V L E Sbjct: 194 LILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSEYKVSLME 253 Query: 254 NVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEES 313 N + TLV+ NA+D DEG+NG++ YS S + P+ + F +D +G + V G +D+EE+ Sbjct: 254 NAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVNGTLDYEEN 312 Query: 314 RAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIALIS 373 + +KI V+A DKG PP+AGHCT+ VE++D NDN+P++ + +LS+PV+EDAQ TVIALIS Sbjct: 313 KFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPSTVIALIS 372 Query: 374 VIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGGSP 433 V D D+ NGQVTCSLTPHVPFKLVST+KNYYSLVLD ALDRE+V AYELVVTARDGGSP Sbjct: 373 VSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVTARDGGSP 432 Query: 434 SLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYS 493 SLWATARVSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSARDADAQENALVSYS Sbjct: 433 SLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYS 492 Query: 494 LVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQV 553 LVERRLG+R+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL SNVTLQV Sbjct: 493 LVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLSSNVTLQV 552 Query: 554 FVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLSYELQP 613 FVLDENDNAPALL + GAV+++V RSVGAG VV KVRAVDADSGYNAWLSYELQP Sbjct: 553 FVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQP 612 Query: 614 ETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVSLVESG 673 + IPFRVGLYTGEISTTRALDE D+PR RLLVLVKDHGEPALTATATVLVSLVESG Sbjct: 613 AAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESG 672 Query: 674 QAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMPTEGECA 733 QAPK+SSR GA PE LVDVNVYLIIAIC VSSLLVLTLLLYT L SA PTEG CA Sbjct: 673 QAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSATPTEGACA 732 Query: 734 PGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCAGSTERTGE 788 PGKPTLVCS AVGSWSYSQQRRQRVCS EG KTDLMAFSP L P + E GE Sbjct: 733 PGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSL-PLGLNKEEEGE 786 >gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo sapiens] Length = 792 Score = 1150 bits (2975), Expect = 0.0 Identities = 599/768 (77%), Positives = 648/768 (84%) Query: 9 PEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDS 68 P Q LLLSLL+LA W VGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELVPRLF++ S Sbjct: 9 PGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68 Query: 69 KGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIND 128 K GDLLEVNLQNGILFVNSRIDRE+LCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIND Sbjct: 69 KRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIND 128 Query: 129 NPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQ 188 NPPVF ++ + ++ES PLDS FPLEGASDADIG N+LLTY LS NE F L + T + Sbjct: 129 NPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDK 188 Query: 189 VKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYT 248 LVLRKLLDRE+TP+L+LLL DGGKPELTG+VQ+ ITVLD NDN P FD+ Y Sbjct: 189 SILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYK 248 Query: 249 VKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHM 308 V L ENV T VI NASD DEGLNG+I Y + K F ++P +G I + G + Sbjct: 249 VVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGEL 308 Query: 309 DFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTV 368 DFEE+ A++I V A+DKG P +AGH +LVEV+DVNDN P++ + +LS+PV+EDAQ+GTV Sbjct: 309 DFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTV 368 Query: 369 IALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTAR 428 IALISV D D+ ANGQV CSLTPHVPFKLVSTYKNYYSLVLD ALDRESVSAYELVVTAR Sbjct: 369 IALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTAR 428 Query: 429 DGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENA 488 DGGSPSLWATARVSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQ+NA Sbjct: 429 DGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNA 488 Query: 489 LVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548 LVSYSLVERR+GE +LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN Sbjct: 489 LVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548 Query: 549 VTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLS 608 VTLQVFVLDENDNAPALL GAVSE+V RSVGAG VV KVRAVDADSGYNAWLS Sbjct: 549 VTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLS 608 Query: 609 YELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVS 668 YELQP A IPF VGLYTGEISTTR LDE DAPR RLLVLVKDHGEPALT+TATVLVS Sbjct: 609 YELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLVS 668 Query: 669 LVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMPT 728 LVE+GQAPK+SSRASVGA PE LVD+NVYLIIAICAVSSLLVLTLLLYT LRCSA PT Sbjct: 669 LVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728 Query: 729 EGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGL 776 CAPGKPTLVCSSAVGSWSYSQQRRQRVCS E KTDLMAFSP L Sbjct: 729 VSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776 >gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo sapiens] Length = 941 Score = 1150 bits (2975), Expect = 0.0 Identities = 599/768 (77%), Positives = 648/768 (84%) Query: 9 PEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDS 68 P Q LLLSLL+LA W VGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELVPRLF++ S Sbjct: 9 PGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68 Query: 69 KGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIND 128 K GDLLEVNLQNGILFVNSRIDRE+LCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIND Sbjct: 69 KRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIND 128 Query: 129 NPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQ 188 NPPVF ++ + ++ES PLDS FPLEGASDADIG N+LLTY LS NE F L + T + Sbjct: 129 NPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDK 188 Query: 189 VKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYT 248 LVLRKLLDRE+TP+L+LLL DGGKPELTG+VQ+ ITVLD NDN P FD+ Y Sbjct: 189 SILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYK 248 Query: 249 VKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHM 308 V L ENV T VI NASD DEGLNG+I Y + K F ++P +G I + G + Sbjct: 249 VVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGEL 308 Query: 309 DFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTV 368 DFEE+ A++I V A+DKG P +AGH +LVEV+DVNDN P++ + +LS+PV+EDAQ+GTV Sbjct: 309 DFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTV 368 Query: 369 IALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTAR 428 IALISV D D+ ANGQV CSLTPHVPFKLVSTYKNYYSLVLD ALDRESVSAYELVVTAR Sbjct: 369 IALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTAR 428 Query: 429 DGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENA 488 DGGSPSLWATARVSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQ+NA Sbjct: 429 DGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNA 488 Query: 489 LVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548 LVSYSLVERR+GE +LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN Sbjct: 489 LVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548 Query: 549 VTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLS 608 VTLQVFVLDENDNAPALL GAVSE+V RSVGAG VV KVRAVDADSGYNAWLS Sbjct: 549 VTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLS 608 Query: 609 YELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVS 668 YELQP A IPF VGLYTGEISTTR LDE DAPR RLLVLVKDHGEPALT+TATVLVS Sbjct: 609 YELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLVS 668 Query: 669 LVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMPT 728 LVE+GQAPK+SSRASVGA PE LVD+NVYLIIAICAVSSLLVLTLLLYT LRCSA PT Sbjct: 669 LVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728 Query: 729 EGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGL 776 CAPGKPTLVCSSAVGSWSYSQQRRQRVCS E KTDLMAFSP L Sbjct: 729 VSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776 >gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo sapiens] Length = 685 Score = 792 bits (2045), Expect = 0.0 Identities = 410/523 (78%), Positives = 449/523 (85%) Query: 12 QPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGR 71 Q LLLSLL+LA W VGSGQLHYSV EEA HGTFVGRIAQDLGLELAELV RLF++ SK Sbjct: 11 QCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASKRH 70 Query: 72 GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPP 131 GDLLEVNLQNGILFVNSRIDREELCGRS ECSIHLEVIVDRPLQVFHVDVEVKDINDNPP Sbjct: 71 GDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDNPP 130 Query: 132 VFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKP 191 F T++ L I ESR LDSRFPLEGASDAD+GENALLTY+LSPNEYF LD+ + K Sbjct: 131 RFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKDKF 190 Query: 192 LGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKL 251 LVLRKLLDREE P+L LLLTATDGGKPE TG+V LLI VLD NDNAP+FDR +Y VK+ Sbjct: 191 PVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEVKM 250 Query: 252 PENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFE 311 EN TLVI NASD DEG+N +++YSFSS V P I+ KF ++ +G I V +DFE Sbjct: 251 YENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAIDFE 310 Query: 312 ESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIAL 371 +S ++I V+ DKG PP+ GHCT+LVE++D NDN+P++ + +LS+PVKEDAQ+GTVIAL Sbjct: 311 DSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVIAL 370 Query: 372 ISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGG 431 ISV D D+ ANGQVTCSLTPHVPFKLVSTYKNYYSLVLD ALDRE VSAYELVVTARDGG Sbjct: 371 ISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARDGG 430 Query: 432 SPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVS 491 SP LWATA VSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSA DADAQENALVS Sbjct: 431 SPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENALVS 490 Query: 492 YSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQ 534 YSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQ Sbjct: 491 YSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQ 533 Score = 134 bits (336), Expect = 5e-31 Identities = 100/341 (29%), Positives = 155/341 (45%), Gaps = 21/341 (6%) Query: 338 VEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKL 397 VEV D+NDN P+ ++ + + E L + L D D N +T L+P+ F L Sbjct: 120 VEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVL 179 Query: 398 VSTYKN----YYSLVLDRALDRESVSAYELVVTARDGGSPSLWATARVSVEVADVNDNAP 453 K + LVL + LDRE +L++TA DGG P + + + V D NDNAP Sbjct: 180 DIINKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAP 239 Query: 454 AFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRLGERSLSSYVSVHAE 513 F + Y V + EN + ++A D+D N + YS L ++ ++ Sbjct: 240 IFDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSS--LVPPTIRRKFWINER 297 Query: 514 SGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLTPRMRGT 573 +G++ +D E+ + V D G PP+ + T+ V +LDENDN+P ++ Sbjct: 298 TGEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVT----- 352 Query: 574 DGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLSYELQPETASASIPFR-VGLYTGEIS 632 ++S V G V+ + D DSG N ++ L P +PF+ V Y S Sbjct: 353 --SLSLPVKEDAQVGTVIALISVSDHDSGANGQVTCSLTPH-----VPFKLVSTYKNYYS 405 Query: 633 TT--RALDETDAPRQRLLVLVKDHGEPALTATATVLVSLVE 671 ALD L+V +D G P L ATA+V V + + Sbjct: 406 LVLDSALDRERVSAYELVVTARDGGSPPLWATASVSVEVAD 446 Score = 132 bits (333), Expect = 1e-30 Identities = 112/387 (28%), Positives = 178/387 (45%), Gaps = 18/387 (4%) Query: 230 ITVLDNNDNAPVFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSD--VSP 287 + V D NDN P F T + +PE+ + + ASD D G N + Y S + Sbjct: 120 VEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVL 179 Query: 288 DIKSKFHMDPLSGAITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNA 347 DI +K D + + +D EE+ K+ + A D G P G +LL+ V+D NDNA Sbjct: 180 DIINKKDKDKFP-VLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNA 238 Query: 348 PQLTIKTLSVPVKEDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTY---KNY 404 P V + E+ T++ ++ D D N ++ S + VP + + + Sbjct: 239 PIFDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERT 298 Query: 405 YSLVLDRALDRESVSAYELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFV 464 + ++ A+D E + YE+ V D G+P + V VE+ D NDN+P + ++ V Sbjct: 299 GEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPV 358 Query: 465 KENNPPGCHIFTVSARDADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLD 524 KE+ G I +S D D+ N V+ SL + + +S+Y + ++ + LD Sbjct: 359 KEDAQVGTVIALISVSDHDSGANGQVTCSLTPH-VPFKLVSTYKNYYS----LVLDSALD 413 Query: 525 HEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRS 584 E + + V+ARD G PPL + ++ V V D NDNAPA + V + Sbjct: 414 RERVSAYELVVTARDGGSPPLWATASVSVEVADVNDNAPAF-------AQSEYTVFVKEN 466 Query: 585 VGAGVVVGKVRAVDADSGYNAWLSYEL 611 G + V A DAD+ NA +SY L Sbjct: 467 NPPGCHIFTVSAWDADAQENALVSYSL 493 Score = 90.9 bits (224), Expect = 4e-18 Identities = 82/272 (30%), Positives = 118/272 (43%), Gaps = 19/272 (6%) Query: 441 VSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRLG 500 V VEV D+NDN P F+ +E + + E+ A DAD ENAL++Y L Sbjct: 118 VDVEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYF 177 Query: 501 ERSLSSYVSVHAESGKVYALQPL-DHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDEN 559 + + + V L+ L D EE L+ ++A D G P +V+L + VLD N Sbjct: 178 VLDIIN--KKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDAN 235 Query: 560 DNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLSYE---LQPETA 616 DNAP P +M V +V+ ++ A D+D G N + Y L P T Sbjct: 236 DNAPIFDRPVYE------VKMYENQVNQTLVI-RLNASDSDEGINKEMMYSFSSLVPPTI 288 Query: 617 SASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVSLVESGQAP 676 F + TGEI A+D D+ + V V D G P + TVLV L++ Sbjct: 289 RRK--FWINERTGEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNS 346 Query: 677 KSSSRASVGATGPEVTLVDVNVYLIIAICAVS 708 S+ E D V +IA+ +VS Sbjct: 347 PEVIVTSLSLPVKE----DAQVGTVIALISVS 374 >gi|14165402 protocadherin alpha 1 isoform 3 precursor [Homo sapiens] Length = 686 Score = 791 bits (2042), Expect = 0.0 Identities = 399/534 (74%), Positives = 461/534 (86%) Query: 1 MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60 M++S RG + LLL LL+LA W VGSGQLHYS+PEEA+HGTFVGR+AQDLGLELAELV Sbjct: 1 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60 Query: 61 PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLF++ SK DLLEVNLQNGILFVNSRIDREELC SAECSIHLE+I DRPLQVFHV+ Sbjct: 61 PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120 Query: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180 V+VKDINDNPPVF ++ +FI ESR L+SRFP+EGA+DADIG NALLTY LSP++YF L Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180 Query: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240 DV S++ K L L LRK LDREETPELHLLLTATDGGKPEL GTV+LLITVLD NDNAP Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240 Query: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300 +FD+ +Y V L E + GTLV NASD DEG+NG++++SF S +S DI+ KF +D SG Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300 Query: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360 I +I +D+EE+++++I V+AVDKG PP++ HC +LV+V+DVNDNAP+L + +L +P++ Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360 Query: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420 EDA L TVIALI+V D D+ ANGQVTCSL PHVPFKLVST+KNYYSLVLD ALDRES+S Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420 Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQ 534 DADAQENALVSYSLVERR+GER+LS+YVSVHAESGKVYALQPLDHEELELLQFQ Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQ 534 Score = 147 bits (370), Expect = 5e-35 Identities = 132/433 (30%), Positives = 200/433 (46%), Gaps = 37/433 (8%) Query: 194 LVLRKLLDREETPE------LHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLY 247 L + +DREE + +HL L A +P V+ + V D NDN PVF Sbjct: 84 LFVNSRIDREELCQWSAECSIHLELIAD---RPLQVFHVE--VKVKDINDNPPVFRGREQ 138 Query: 248 TVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSD--VSPDIKSKFHMDPLSGAI--T 303 + +PE+ + + A+D D G N + Y+ S S D+++ D LS ++ Sbjct: 139 IIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSLDVEAS---DELSKSLWLE 195 Query: 304 VIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDA 363 + ++D EE+ + + A D G P L G LL+ V+DVNDNAP V + E Sbjct: 196 LRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAPLFDQAVYRVHLLETT 255 Query: 364 QLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYS---LVLDRALDRESVSA 420 GT++ ++ D D NG+V S + + +K S + L LD E + Sbjct: 256 ANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSGEIRLIDKLDYEETKS 315 Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480 YE+ V A D GSP + +V V+V DVNDNAP A + + ++E+ P I ++ Sbjct: 316 YEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIREDAPLSTVIALITVS 375 Query: 481 DADAQENALVSYSLVERRLGE--RSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSAR 538 D D+ N V+ SL+ + + +Y S+ +S LD E L + + V+AR Sbjct: 376 DRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSA-------LDRESLSVYELVVTAR 428 Query: 539 DAGVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVD 598 D G P L + + V V D NDNAPA P + V + G + V A D Sbjct: 429 DGGSPSLWATARVSVEVADVNDNAPAFAQPE-------YTVFVKENNPPGCHIFTVSARD 481 Query: 599 ADSGYNAWLSYEL 611 AD+ NA +SY L Sbjct: 482 ADAQENALVSYSL 494 Score = 144 bits (364), Expect = 3e-34 Identities = 110/344 (31%), Positives = 158/344 (45%), Gaps = 27/344 (7%) Query: 338 VEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKL 397 V+V D+NDN P + + + E L + + D D AN +T +L+P F L Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180 Query: 398 VSTYKNYYS----LVLDRALDRESVSAYELVVTARDGGSPSLWATARVSVEVADVNDNAP 453 + S L L + LDRE L++TA DGG P L T + + V DVNDNAP Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240 Query: 454 AFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRLGERSLSSYVSVHAE 513 F Q+ Y V + E G + T++A DAD N V +S R + V + Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGI--SRDIQEKFKVDSS 298 Query: 514 SGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLTPRMRGT 573 SG++ + LD+EE + + QV A D G PP+ ++ + V VLD NDNAP L Sbjct: 299 SGEIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPEL-------- 350 Query: 574 DGAVSEMVL---RSVGAGVVVGKVRAVDADSGYNAWLSYELQPETASASIPFR-VGLYTG 629 AV+ + L V+ + D DSG N ++ L P +PF+ V + Sbjct: 351 --AVTSLYLPIREDAPLSTVIALITVSDRDSGANGQVTCSLMPH-----VPFKLVSTFKN 403 Query: 630 EISTT--RALDETDAPRQRLLVLVKDHGEPALTATATVLVSLVE 671 S ALD L+V +D G P+L ATA V V + + Sbjct: 404 YYSLVLDSALDRESLSVYELVVTARDGGSPSLWATARVSVEVAD 447 >gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo sapiens] Length = 686 Score = 781 bits (2017), Expect = 0.0 Identities = 394/523 (75%), Positives = 449/523 (85%) Query: 12 QPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGR 71 Q LLL LL+LA W VGSGQLHYSVPEEA+HGTFVGRIAQDLGLELAELVPRLF++ SK R Sbjct: 12 QCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDR 71 Query: 72 GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPP 131 DLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEV+DINDNPP Sbjct: 72 EDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPP 131 Query: 132 VFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKP 191 +FP ++ + I ESR DS FPLEGASDAD+G N++LTY+LS +EYF LDV ++ K Sbjct: 132 LFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQ 191 Query: 192 LGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKL 251 +GL+L+K LDREE P +L LTATDGGKPELTGTVQLL+TVLD NDNAP F+++ Y V++ Sbjct: 192 IGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRI 251 Query: 252 PENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFE 311 EN GT VI NASD DEG NG I YSF+S V+ + F +D +G I + G++DFE Sbjct: 252 FENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFE 311 Query: 312 ESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIAL 371 + +KI ++A DKG PP+AGHCT+LV ++D NDN P++ + +LS+PV+EDAQ GTVIAL Sbjct: 312 QENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIAL 371 Query: 372 ISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGG 431 ISV DLD+ ANGQV CSLTPHVPFKLVST+KNYYSLVLD ALDRESVSAYELVVTARDGG Sbjct: 372 ISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG 431 Query: 432 SPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVS 491 SPSLWATA +SVEVAD+NDNAPAFAQ EYTVFVKENNPPGCHIFTVSARDADAQENALVS Sbjct: 432 SPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVS 491 Query: 492 YSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQ 534 YSLVERR+GER+LSSY+SVHAESGKVYALQPLDHEELELLQFQ Sbjct: 492 YSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQ 534 Score = 155 bits (393), Expect = 1e-37 Identities = 109/341 (31%), Positives = 161/341 (47%), Gaps = 21/341 (6%) Query: 338 VEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIALISVIDLDADANGQVTCSLTPHVPF-- 395 VEV D+NDN P ++ V + E +V L D D +N +T L+ F Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180 Query: 396 --KLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGGSPSLWATARVSVEVADVNDNAP 453 K+ S L+L ++LDRE A+ L +TA DGG P L T ++ V V DVNDNAP Sbjct: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 Query: 454 AFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRLGERSLSSYVSVHAE 513 F QSEY V + EN G + ++A D D N +SYS L + + S+ Sbjct: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSF--NSLVAAMVIDHFSIDRN 298 Query: 514 SGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLTPRMRGT 573 +G++ LD E+ L + + A D G PP+ + T+ V +LD+NDN P + Sbjct: 299 TGEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALT----- 353 Query: 574 DGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLSYELQPETASASIPFR-VGLYTGEIS 632 ++S V G V+ + D DSG N ++ L P +PF+ V + S Sbjct: 354 --SLSLPVREDAQFGTVIALISVNDLDSGANGQVNCSLTPH-----VPFKLVSTFKNYYS 406 Query: 633 TT--RALDETDAPRQRLLVLVKDHGEPALTATATVLVSLVE 671 ALD L+V +D G P+L ATA++ V + + Sbjct: 407 LVLDSALDRESVSAYELVVTARDGGSPSLWATASLSVEVAD 447 Score = 150 bits (379), Expect = 5e-36 Identities = 119/388 (30%), Positives = 178/388 (45%), Gaps = 20/388 (5%) Query: 230 ITVLDNNDNAPVFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDI 289 + V D NDN P+F V + E+ ++ ASD D G N + Y SS + Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180 Query: 290 KSKFHMDPLSG-AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAP 348 K + D + + +D EE+ AH + + A D G P L G LLV V+DVNDNAP Sbjct: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 Query: 349 QLTIKTLSVPVKEDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTY---KNYY 405 V + E+A GT + ++ D D ANG ++ S V ++ + +N Sbjct: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300 Query: 406 SLVLDRALDRESVSAYELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVK 465 +V+ LD E + Y++++ A D G P + V V + D NDN P A + ++ V+ Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 Query: 466 ENNPPGCHIFTVSARDADAQENALVSYSLVERRLGE--RSLSSYVSVHAESGKVYALQPL 523 E+ G I +S D D+ N V+ SL + + +Y S+ +S L Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSA-------L 413 Query: 524 DHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLR 583 D E + + V+ARD G P L + +L V V D NDNAPA P + V Sbjct: 414 DRESVSAYELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPE-------YTVFVKE 466 Query: 584 SVGAGVVVGKVRAVDADSGYNAWLSYEL 611 + G + V A DAD+ NA +SY L Sbjct: 467 NNPPGCHIFTVSARDADAQENALVSYSL 494 >gi|14277677 protocadherin gamma subfamily C, 3 isoform 2 precursor [Homo sapiens] Length = 863 Score = 593 bits (1528), Expect = e-169 Identities = 336/814 (41%), Positives = 487/814 (59%), Gaps = 27/814 (3%) Query: 18 LLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGRGDLLEV 77 LL+L S +HY +PEE E G VG + +LGL+L L R F++ S EV Sbjct: 20 LLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFEV 79 Query: 78 NLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPPVFPATQ 137 N + G +FVN R+DREELCG C++ LE++V+ PL++F V+V ++DINDN P FP + Sbjct: 80 NRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQE 139 Query: 138 KNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLGLVLR 197 L I+E+ +RFPLE A D D+G N+L TY LS NEYF L V T K LVL Sbjct: 140 MKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVLE 199 Query: 198 KLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPENVSI 257 + LDRE P L L+LTA DGG P L+ ++ + I VLD NDNAPVF+++LY ++ E+ Sbjct: 200 RALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAPS 259 Query: 258 GTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEESRAHK 317 GT V+ A+DLDEG NG+IIYSF S ++ F +D ++G +T+ G +DFE+++ H+ Sbjct: 260 GTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLHE 319 Query: 318 IPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIALISVIDL 377 I ++A DKG P HC +LVEVVDVNDNAP++T+ ++ PV EDA LGTVIAL+SV DL Sbjct: 320 IYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTDL 379 Query: 378 DADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGGSPSLWA 437 DA NG VTC + P +PF L S+ KNY++L LDRE+V Y L +TARD G+PSL A Sbjct: 380 DAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLSA 439 Query: 438 TARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVER 497 V V+V+D+NDN P +QS Y V+++ENN PG I +S D DA +NA +S+ L+E+ Sbjct: 440 LTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLEQ 499 Query: 498 RLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLD 557 + Y +++ ++G V +L PLD+E+ + D G P L +N+++ +FV D Sbjct: 500 GAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVTD 559 Query: 558 ENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLSYELQPETAS 617 NDNAP +L PR G+ EM+ R AG +V +V DAD+G+NAWLSY L Sbjct: 560 RNDNAPQVLYPR---PGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSPNQ 616 Query: 618 ASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVSLVESGQAPK 677 + F +GL+TG+IST R + +TD+PRQ L VL+KD+GEP+L+ TAT+ VS+ E +P+ Sbjct: 617 SL--FAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTE--DSPE 672 Query: 678 SSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLT---LLLYTVLRCS------AMPT 728 + + G + P ++ YL++++ VS V+T ++++ V + P Sbjct: 673 ARAEFPSG-SAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYRAPV 731 Query: 729 EGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCAG--STERT 786 P+L + G Q + + ++ L+ SP A +T R+ Sbjct: 732 SSLYRTPGPSLHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQNTLRS 791 Query: 787 GEP-------SASSDSTGKVGFS-SILFIYIIFF 812 +P A S G+V FS S L + ++F+ Sbjct: 792 CDPVFYRQVLGAESAPPGQVRFSKSCLTLLVLFY 825 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.135 0.386 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 31,769,826 Number of Sequences: 37866 Number of extensions: 1443025 Number of successful extensions: 9879 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 187 Number of HSP's successfully gapped in prelim test: 23 Number of HSP's that attempted gapping in prelim test: 3024 Number of HSP's gapped (non-prelim): 697 length of query: 842 length of database: 18,247,518 effective HSP length: 111 effective length of query: 731 effective length of database: 14,044,392 effective search space: 10266450552 effective search space used: 10266450552 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.