Search of human proteins with 7662068

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo
sapiens]
         (842 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens]  1647   0.0  
gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo sapi...  1563   0.0  
gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens]  1361   0.0  
gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo sapi...  1358   0.0  
gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo sapi...  1261   0.0  
gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens]  1259   0.0  
gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo sapi...  1238   0.0  
gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens]  1236   0.0  
gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo sapi...  1201   0.0  
gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo sap...  1200   0.0  
gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo sapi...  1200   0.0  
gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens]  1199   0.0  
gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo sapi...  1193   0.0  
gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens]  1192   0.0  
gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo sap...  1191   0.0  
gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo sapi...  1185   0.0  
gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens]  1184   0.0  
gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens]  1181   0.0  
gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo sapi...  1180   0.0  
gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapi...  1178   0.0  
gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo sapi...  1174   0.0  
gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens]  1170   0.0  
gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo sap...  1160   0.0  
gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo sapi...  1157   0.0  
gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo sap...  1150   0.0  
gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo sapi...  1150   0.0  
gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo sap...   792   0.0  
gi|14165402 protocadherin alpha 1 isoform 3 precursor [Homo sapi...   791   0.0  
gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo sapi...   781   0.0  
gi|14277677 protocadherin gamma subfamily C, 3 isoform 2 precurs...   593   e-169

>gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens]
          Length = 842

 Score = 1647 bits (4264), Expect = 0.0
 Identities = 842/842 (100%), Positives = 842/842 (100%)

Query: 1   MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60
           MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV
Sbjct: 1   MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD
Sbjct: 61  PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120

Query: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180
           VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL
Sbjct: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180

Query: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240
           DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP
Sbjct: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240

Query: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300
           VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG
Sbjct: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300

Query: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360
           AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK
Sbjct: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360

Query: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420
           EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA
Sbjct: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480
           YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR
Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA
Sbjct: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600

Query: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660
           SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660

Query: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720
           ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV
Sbjct: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720

Query: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780
           LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA
Sbjct: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780

Query: 781 GSTERTGEPSASSDSTGKVGFSSILFIYIIFFLERYYRLLPGAVQIVLFIFLEIQQIFFL 840
           GSTERTGEPSASSDSTGKVGFSSILFIYIIFFLERYYRLLPGAVQIVLFIFLEIQQIFFL
Sbjct: 781 GSTERTGEPSASSDSTGKVGFSSILFIYIIFFLERYYRLLPGAVQIVLFIFLEIQQIFFL 840

Query: 841 IK 842
           IK
Sbjct: 841 IK 842


>gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo
           sapiens]
          Length = 950

 Score = 1563 bits (4048), Expect = 0.0
 Identities = 798/798 (100%), Positives = 798/798 (100%)

Query: 1   MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60
           MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV
Sbjct: 1   MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD
Sbjct: 61  PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120

Query: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180
           VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL
Sbjct: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180

Query: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240
           DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP
Sbjct: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240

Query: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300
           VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG
Sbjct: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300

Query: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360
           AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK
Sbjct: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360

Query: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420
           EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA
Sbjct: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480
           YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR
Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA
Sbjct: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600

Query: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660
           SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660

Query: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720
           ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV
Sbjct: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720

Query: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780
           LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA
Sbjct: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780

Query: 781 GSTERTGEPSASSDSTGK 798
           GSTERTGEPSASSDSTGK
Sbjct: 781 GSTERTGEPSASSDSTGK 798


>gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens]
          Length = 937

 Score = 1361 bits (3522), Expect = 0.0
 Identities = 697/783 (89%), Positives = 724/783 (92%)

Query: 8   DPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLD 67
           DP G+ LLL ++ILA W  G GQLHYSVPEEA+HG FVGRIAQDLGLELAELVPRLF+  
Sbjct: 8   DPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAV 67

Query: 68  SKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIN 127
            K RGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIV+RPLQVFHVDVEVKDIN
Sbjct: 68  CKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDIN 127

Query: 128 DNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQ 187
           DNPPVFPATQ+NLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQ
Sbjct: 128 DNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQ 187

Query: 188 QVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLY 247
           QVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLY
Sbjct: 188 QVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLY 247

Query: 248 TVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGH 307
           TVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGH
Sbjct: 248 TVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGH 307

Query: 308 MDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGT 367
           MDFEESRAHKIPVEAVDKGFPPLAGHCT+LVEVVDVNDNAPQLT+ +LS+P+ EDAQ GT
Sbjct: 308 MDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGT 367

Query: 368 VIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTA 427
           VI LISV D D   NGQVTCSLTP VPFKLVST+KNYYSLVLD ALDRESVSAYELVVTA
Sbjct: 368 VITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTA 427

Query: 428 RDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQEN 487
           RDGGSPSLWATA VSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQ+N
Sbjct: 428 RDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKN 487

Query: 488 ALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS 547
           ALVSYSLVE R+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS
Sbjct: 488 ALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS 547

Query: 548 NVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWL 607
           NVTLQVFVLDENDNAPALL PR+ GT GAV E+V RSVGAG VV KVRAVDADSGYNAWL
Sbjct: 548 NVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWL 607

Query: 608 SYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLV 667
           SYELQP  A ASIPFRVGLYTGEISTTRALDETDAPR RLLVLVKDHGEP+LTATATVLV
Sbjct: 608 SYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLV 667

Query: 668 SLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMP 727
           SLVESGQAPK+SSRAS+G  GPE  LVDVNVYLIIAICAVSSLLVLTLLLYT LRCSA  
Sbjct: 668 SLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPS 727

Query: 728 TEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCAGSTERTG 787
           +EG C+  KPTLVCSSAVGSWS+SQQRRQRVCSGEG  KTDLMAFSP L     ST+   
Sbjct: 728 SEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTDNPR 787

Query: 788 EPS 790
           +P+
Sbjct: 788 QPN 790


>gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo
           sapiens]
          Length = 789

 Score = 1358 bits (3515), Expect = 0.0
 Identities = 696/777 (89%), Positives = 721/777 (92%)

Query: 8   DPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLD 67
           DP G+ LLL ++ILA W  G GQLHYSVPEEA+HG FVGRIAQDLGLELAELVPRLF+  
Sbjct: 8   DPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAV 67

Query: 68  SKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIN 127
            K RGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIV+RPLQVFHVDVEVKDIN
Sbjct: 68  CKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDIN 127

Query: 128 DNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQ 187
           DNPPVFPATQ+NLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQ
Sbjct: 128 DNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQ 187

Query: 188 QVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLY 247
           QVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLY
Sbjct: 188 QVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLY 247

Query: 248 TVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGH 307
           TVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGH
Sbjct: 248 TVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGH 307

Query: 308 MDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGT 367
           MDFEESRAHKIPVEAVDKGFPPLAGHCT+LVEVVDVNDNAPQLT+ +LS+P+ EDAQ GT
Sbjct: 308 MDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGT 367

Query: 368 VIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTA 427
           VI LISV D D   NGQVTCSLTP VPFKLVST+KNYYSLVLD ALDRESVSAYELVVTA
Sbjct: 368 VITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTA 427

Query: 428 RDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQEN 487
           RDGGSPSLWATA VSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQ+N
Sbjct: 428 RDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKN 487

Query: 488 ALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS 547
           ALVSYSLVE R+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS
Sbjct: 488 ALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS 547

Query: 548 NVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWL 607
           NVTLQVFVLDENDNAPALL PR+ GT GAV E+V RSVGAG VV KVRAVDADSGYNAWL
Sbjct: 548 NVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWL 607

Query: 608 SYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLV 667
           SYELQP  A ASIPFRVGLYTGEISTTRALDETDAPR RLLVLVKDHGEP+LTATATVLV
Sbjct: 608 SYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLV 667

Query: 668 SLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMP 727
           SLVESGQAPK+SSRAS+G  GPE  LVDVNVYLIIAICAVSSLLVLTLLLYT LRCSA  
Sbjct: 668 SLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPS 727

Query: 728 TEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCAGSTE 784
           +EG C+  KPTLVCSSAVGSWS+SQQRRQRVCSGEG  KTDLMAFSP L     ST+
Sbjct: 728 SEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTD 784


>gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo
           sapiens]
          Length = 798

 Score = 1261 bits (3262), Expect = 0.0
 Identities = 651/799 (81%), Positives = 701/799 (87%), Gaps = 3/799 (0%)

Query: 1   MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60
           M +S     E + LLL LL+LA W  G+GQLHYSV EEA+HGTFVGRIAQDLGLELAELV
Sbjct: 1   MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLF++ SKGRG LLEVNLQNGILFVNSRIDREELC RSAECSIHLEVIVDRPLQVFHVD
Sbjct: 61  PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD 120

Query: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180
           VEV+DINDNPPVFPATQKNL IAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYF L
Sbjct: 121 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL 180

Query: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240
           + P  ++ VK LGL+LRK LDREE PE+ L+LTATDGGKPELTGTVQLLITVLD NDNAP
Sbjct: 181 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP 240

Query: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300
            FDRT+Y V+L ENV  GTLVI  NASDLDEGLNGDI+YSFS+D+SP++KSKFH+DP++G
Sbjct: 241 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG 300

Query: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360
            I V G++DFEES++++I VE +DKG  PL+GHC ++VEV D NDN P L  K+LS+P++
Sbjct: 301 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR 360

Query: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420
           EDA LGTVIALISV D D   NG VTCSLT HVPFKLVST+KNYYSLVLD ALDRESVSA
Sbjct: 361 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480
           YELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA 
Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480

Query: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQENALVSYSLVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARDA
Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL PR  GT GAVSE+V  SVG G VV KVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660
           SGYNAWLSYELQP T  A IPFRVGLYTGEISTTRALDETDAPR RLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT 660

Query: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720
           ATATVLVSLVESGQAPK+SSRA VGA GP+  LVDVNVYLIIAICAVSSLLVLTLLLYT 
Sbjct: 661 ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780
           LRCSA+PTEG CAPGKPTLVCSSAVGSWSYSQQRR RVCSGEG  KTDLMAFSP L    
Sbjct: 721 LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSL---P 777

Query: 781 GSTERTGEPSASSDSTGKV 799
            S +R  +   + +S  KV
Sbjct: 778 DSRDREDQLQTTEESFAKV 796


>gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens]
          Length = 947

 Score = 1259 bits (3258), Expect = 0.0
 Identities = 650/798 (81%), Positives = 700/798 (87%), Gaps = 3/798 (0%)

Query: 1   MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60
           M +S     E + LLL LL+LA W  G+GQLHYSV EEA+HGTFVGRIAQDLGLELAELV
Sbjct: 1   MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLF++ SKGRG LLEVNLQNGILFVNSRIDREELC RSAECSIHLEVIVDRPLQVFHVD
Sbjct: 61  PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD 120

Query: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180
           VEV+DINDNPPVFPATQKNL IAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYF L
Sbjct: 121 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL 180

Query: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240
           + P  ++ VK LGL+LRK LDREE PE+ L+LTATDGGKPELTGTVQLLITVLD NDNAP
Sbjct: 181 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP 240

Query: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300
            FDRT+Y V+L ENV  GTLVI  NASDLDEGLNGDI+YSFS+D+SP++KSKFH+DP++G
Sbjct: 241 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG 300

Query: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360
            I V G++DFEES++++I VE +DKG  PL+GHC ++VEV D NDN P L  K+LS+P++
Sbjct: 301 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR 360

Query: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420
           EDA LGTVIALISV D D   NG VTCSLT HVPFKLVST+KNYYSLVLD ALDRESVSA
Sbjct: 361 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480
           YELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA 
Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480

Query: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQENALVSYSLVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARDA
Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL PR  GT GAVSE+V  SVG G VV KVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660
           SGYNAWLSYELQP T  A IPFRVGLYTGEISTTRALDETDAPR RLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT 660

Query: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720
           ATATVLVSLVESGQAPK+SSRA VGA GP+  LVDVNVYLIIAICAVSSLLVLTLLLYT 
Sbjct: 661 ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780
           LRCSA+PTEG CAPGKPTLVCSSAVGSWSYSQQRR RVCSGEG  KTDLMAFSP L    
Sbjct: 721 LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSL---P 777

Query: 781 GSTERTGEPSASSDSTGK 798
            S +R  +   + +S  K
Sbjct: 778 DSRDREDQLQTTEESFAK 795


>gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo
           sapiens]
          Length = 824

 Score = 1238 bits (3202), Expect = 0.0
 Identities = 635/806 (78%), Positives = 701/806 (86%)

Query: 1   MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60
           ML+S R DP  Q LLLSLL+LA   VGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV
Sbjct: 1   MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLF++ SK  GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+
Sbjct: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120

Query: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180
           VEVKDINDN PVFP   KNLFI+ESR   SRF LEGASDADIG N+LLTY L   EYF L
Sbjct: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180

Query: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240
           DV  +++++K LGLVL+K L+RE+TP+ +LL+TA DGGKPELTGT QL ITVLD NDNAP
Sbjct: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240

Query: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300
            F+RT+Y V+L EN   GTLV+  NA+DLDEG+N DI YSF++D+S DI SKFH+DP++G
Sbjct: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300

Query: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360
            I+V G++DFEES++++I VEA DKG PP++ HCT+L+E+VD+NDN P+L I++LS+PV 
Sbjct: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360

Query: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420
           ED+ L TVIALISV D D+  NGQVTCSLTPHVPFKLVST+KNYYSLVLD  LDRESVSA
Sbjct: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480
           YELVVTARDGGSPSLWATA VSVEVADVNDNAPAF+QSEYTVFVKENNPPGCHIFTVSAR
Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQENALVSYSLVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA
Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL PR+ G  GAVSE+V RSVGAG VV KVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660
           SGYNAWLSYELQP T  A IPFRVGLYTGEISTTRALDE DAPR RLLVLVKDHGEP+LT
Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660

Query: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720
           ATATVLVSLVESGQAPK+SS+AS GATGPE  LVDVNVYLI+AICAVSSLLVLTLLLYT 
Sbjct: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780
           LRCSA PTEG+C PGKPTLVCSSAVGSWSYSQQR+QRVCSGEG  KTDLMAFSP L PC 
Sbjct: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780

Query: 781 GSTERTGEPSASSDSTGKVGFSSILF 806
            S +R  +     D + KV    + F
Sbjct: 781 ISRDREEKQDVDVDLSAKVSNFYLFF 806


>gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score = 1236 bits (3197), Expect = 0.0
 Identities = 633/798 (79%), Positives = 698/798 (87%)

Query: 1   MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60
           ML+S R DP  Q LLLSLL+LA   VGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV
Sbjct: 1   MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLF++ SK  GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+
Sbjct: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120

Query: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180
           VEVKDINDN PVFP   KNLFI+ESR   SRF LEGASDADIG N+LLTY L   EYF L
Sbjct: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180

Query: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240
           DV  +++++K LGLVL+K L+RE+TP+ +LL+TA DGGKPELTGT QL ITVLD NDNAP
Sbjct: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240

Query: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300
            F+RT+Y V+L EN   GTLV+  NA+DLDEG+N DI YSF++D+S DI SKFH+DP++G
Sbjct: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300

Query: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360
            I+V G++DFEES++++I VEA DKG PP++ HCT+L+E+VD+NDN P+L I++LS+PV 
Sbjct: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360

Query: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420
           ED+ L TVIALISV D D+  NGQVTCSLTPHVPFKLVST+KNYYSLVLD  LDRESVSA
Sbjct: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480
           YELVVTARDGGSPSLWATA VSVEVADVNDNAPAF+QSEYTVFVKENNPPGCHIFTVSAR
Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQENALVSYSLVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA
Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL PR+ G  GAVSE+V RSVGAG VV KVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660
           SGYNAWLSYELQP T  A IPFRVGLYTGEISTTRALDE DAPR RLLVLVKDHGEP+LT
Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660

Query: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720
           ATATVLVSLVESGQAPK+SS+AS GATGPE  LVDVNVYLI+AICAVSSLLVLTLLLYT 
Sbjct: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780
           LRCSA PTEG+C PGKPTLVCSSAVGSWSYSQQR+QRVCSGEG  KTDLMAFSP L PC 
Sbjct: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780

Query: 781 GSTERTGEPSASSDSTGK 798
            S +R  +     D + K
Sbjct: 781 ISRDREEKQDVDVDLSAK 798


>gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 807

 Score = 1201 bits (3106), Expect = 0.0
 Identities = 615/799 (76%), Positives = 686/799 (85%)

Query: 1   MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60
           M++S RG    + LLL LL+LA W VGSGQLHYS+PEEA+HGTFVGR+AQDLGLELAELV
Sbjct: 1   MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60

Query: 61  PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLF++ SK   DLLEVNLQNGILFVNSRIDREELC  SAECSIHLE+I DRPLQVFHV+
Sbjct: 61  PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120

Query: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180
           V+VKDINDNPPVF   ++ +FI ESR L+SRFP+EGA+DADIG NALLTY LSP++YF L
Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180

Query: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240
           DV  S++  K L L LRK LDREETPELHLLLTATDGGKPEL GTV+LLITVLD NDNAP
Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240

Query: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300
           +FD+ +Y V L E  + GTLV   NASD DEG+NG++++SF S +S DI+ KF +D  SG
Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300

Query: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360
            I +I  +D+EE+++++I V+AVDKG PP++ HC +LV+V+DVNDNAP+L + +L +P++
Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360

Query: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420
           EDA L TVIALI+V D D+ ANGQVTCSL PHVPFKLVST+KNYYSLVLD ALDRES+S 
Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420

Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480
           YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSAR
Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQENALVSYSLVERR+GER+LS+YVSVHAESGKVYALQPLDHEELELLQFQVSARDA
Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL PR+ GT GAVSE+V R VGAG VV KVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660
           SGYNAWLSYELQP    A IPFRVGLYTGEISTTR LDE D  R RLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT 660

Query: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720
           ATATVLVSLVESGQAPK+SSRASVG  GPE  LVDVNVYLIIAICAVSSLLVLTLLLYT 
Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780
           LRCS  PTEG   PGKPTLVCSSA+GSWS SQQRRQRVCS EG  KTDLMAFSPGLSP  
Sbjct: 721 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL 780

Query: 781 GSTERTGEPSASSDSTGKV 799
            ++ER  +P A+ D +G V
Sbjct: 781 NTSERNEQPEANLDLSGNV 799


>gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo
           sapiens]
          Length = 807

 Score = 1200 bits (3105), Expect = 0.0
 Identities = 618/799 (77%), Positives = 678/799 (84%)

Query: 1   MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60
           ML S +G P  + LLL LLILA W  GSGQLHYSVPEEA+HGTFVGRIAQDLGLELAELV
Sbjct: 1   MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLF++ SK  GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+
Sbjct: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120

Query: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180
           V+V+DINDNPP+FP ++K + IAESRP ++RFPL+GASDADIG N+ LTYRL PN+YF L
Sbjct: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180

Query: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240
           D   S +Q+  L LVLRK LDREE  E  LLLTA+DGGKPELTGTVQLLIT+LD NDNAP
Sbjct: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240

Query: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300
            F +++Y V + EN   GTLVI  NA+D D+G NGDI+YSF   V P +   F ++P +G
Sbjct: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300

Query: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360
            I   G +DFEE + ++I VEAVDKG  P+AGHCTLLVEV+DVNDNAP++TI +LS+P++
Sbjct: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360

Query: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420
           ED Q   +IALISV D D+ +NGQVTC+LTPHVPFKLVSTYKNYYSLVLD ALDRESVSA
Sbjct: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480
           YELVVTARDGGSPSLWATA VSV VADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA+
Sbjct: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480

Query: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQENALVSYSLVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD+
Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALLTP      G VSE++ RSVGAG VV KVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660
           SGYNAWLSYELQ     A IPFRVGLYTGEISTTR LDE DAP  RLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660

Query: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720
           ATATVL+SLVESGQAP++SSRAS GA GPE  LVDVNVYLIIAICAVSSLLVLTLLLYT 
Sbjct: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780
           LRCSA PTEG CAPGKPTLVCSSA GSWSYSQQRR RVCSGEG  KTDLMAFSP L PC 
Sbjct: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL 780

Query: 781 GSTERTGEPSASSDSTGKV 799
           GS E TG+    S+   +V
Sbjct: 781 GSAEGTGQREEDSECLKEV 799


>gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo
           sapiens]
          Length = 950

 Score = 1200 bits (3104), Expect = 0.0
 Identities = 617/794 (77%), Positives = 676/794 (85%)

Query: 1   MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60
           ML S +G P  + LLL LLILA W  GSGQLHYSVPEEA+HGTFVGRIAQDLGLELAELV
Sbjct: 1   MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLF++ SK  GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+
Sbjct: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120

Query: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180
           V+V+DINDNPP+FP ++K + IAESRP ++RFPL+GASDADIG N+ LTYRL PN+YF L
Sbjct: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180

Query: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240
           D   S +Q+  L LVLRK LDREE  E  LLLTA+DGGKPELTGTVQLLIT+LD NDNAP
Sbjct: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240

Query: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300
            F +++Y V + EN   GTLVI  NA+D D+G NGDI+YSF   V P +   F ++P +G
Sbjct: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300

Query: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360
            I   G +DFEE + ++I VEAVDKG  P+AGHCTLLVEV+DVNDNAP++TI +LS+P++
Sbjct: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360

Query: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420
           ED Q   +IALISV D D+ +NGQVTC+LTPHVPFKLVSTYKNYYSLVLD ALDRESVSA
Sbjct: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480
           YELVVTARDGGSPSLWATA VSV VADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA+
Sbjct: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480

Query: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQENALVSYSLVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD+
Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALLTP      G VSE++ RSVGAG VV KVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660
           SGYNAWLSYELQ     A IPFRVGLYTGEISTTR LDE DAP  RLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660

Query: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720
           ATATVL+SLVESGQAP++SSRAS GA GPE  LVDVNVYLIIAICAVSSLLVLTLLLYT 
Sbjct: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780
           LRCSA PTEG CAPGKPTLVCSSA GSWSYSQQRR RVCSGEG  KTDLMAFSP L PC 
Sbjct: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL 780

Query: 781 GSTERTGEPSASSD 794
           GS E TG+    S+
Sbjct: 781 GSAEGTGQREEDSE 794


>gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score = 1199 bits (3102), Expect = 0.0
 Identities = 614/797 (77%), Positives = 685/797 (85%)

Query: 1   MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60
           M++S RG    + LLL LL+LA W VGSGQLHYS+PEEA+HGTFVGR+AQDLGLELAELV
Sbjct: 1   MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60

Query: 61  PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLF++ SK   DLLEVNLQNGILFVNSRIDREELC  SAECSIHLE+I DRPLQVFHV+
Sbjct: 61  PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120

Query: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180
           V+VKDINDNPPVF   ++ +FI ESR L+SRFP+EGA+DADIG NALLTY LSP++YF L
Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180

Query: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240
           DV  S++  K L L LRK LDREETPELHLLLTATDGGKPEL GTV+LLITVLD NDNAP
Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240

Query: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300
           +FD+ +Y V L E  + GTLV   NASD DEG+NG++++SF S +S DI+ KF +D  SG
Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300

Query: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360
            I +I  +D+EE+++++I V+AVDKG PP++ HC +LV+V+DVNDNAP+L + +L +P++
Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360

Query: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420
           EDA L TVIALI+V D D+ ANGQVTCSL PHVPFKLVST+KNYYSLVLD ALDRES+S 
Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420

Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480
           YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSAR
Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQENALVSYSLVERR+GER+LS+YVSVHAESGKVYALQPLDHEELELLQFQVSARDA
Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL PR+ GT GAVSE+V R VGAG VV KVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660
           SGYNAWLSYELQP    A IPFRVGLYTGEISTTR LDE D  R RLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT 660

Query: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720
           ATATVLVSLVESGQAPK+SSRASVG  GPE  LVDVNVYLIIAICAVSSLLVLTLLLYT 
Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780
           LRCS  PTEG   PGKPTLVCSSA+GSWS SQQRRQRVCS EG  KTDLMAFSPGLSP  
Sbjct: 721 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL 780

Query: 781 GSTERTGEPSASSDSTG 797
            ++ER  +P A+ D +G
Sbjct: 781 NTSERNEQPEANLDLSG 797


>gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo
           sapiens]
          Length = 803

 Score = 1193 bits (3086), Expect = 0.0
 Identities = 610/788 (77%), Positives = 673/788 (85%)

Query: 12  QPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGR 71
           Q LLL LL+LA W VGSGQLHYSVPEEA+HGTFVGRIAQDLGLELAELVPRLF++ SK R
Sbjct: 12  QCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDR 71

Query: 72  GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPP 131
            DLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEV+DINDNPP
Sbjct: 72  EDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPP 131

Query: 132 VFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKP 191
           +FP  ++ + I ESR  DS FPLEGASDAD+G N++LTY+LS +EYF LDV  ++   K 
Sbjct: 132 LFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQ 191

Query: 192 LGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKL 251
           +GL+L+K LDREE P  +L LTATDGGKPELTGTVQLL+TVLD NDNAP F+++ Y V++
Sbjct: 192 IGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRI 251

Query: 252 PENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFE 311
            EN   GT VI  NASD DEG NG I YSF+S V+  +   F +D  +G I + G++DFE
Sbjct: 252 FENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFE 311

Query: 312 ESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIAL 371
           +   +KI ++A DKG PP+AGHCT+LV ++D NDN P++ + +LS+PV+EDAQ GTVIAL
Sbjct: 312 QENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIAL 371

Query: 372 ISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGG 431
           ISV DLD+ ANGQV CSLTPHVPFKLVST+KNYYSLVLD ALDRESVSAYELVVTARDGG
Sbjct: 372 ISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG 431

Query: 432 SPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVS 491
           SPSLWATA +SVEVAD+NDNAPAFAQ EYTVFVKENNPPGCHIFTVSARDADAQENALVS
Sbjct: 432 SPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVS 491

Query: 492 YSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL 551
           YSLVERR+GER+LSSY+SVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL
Sbjct: 492 YSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL 551

Query: 552 QVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLSYEL 611
           QVFVLDENDNAPALL PR+ GT GAVSE+V RS+GAG VV KVRAVDADSGYNAWLSYEL
Sbjct: 552 QVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSYEL 611

Query: 612 QPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVSLVE 671
           QP  +SA  PFRVGLYTGEISTTR LDE D+PR RLLVLVKDHGEPALTATATVLVSLVE
Sbjct: 612 QPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVE 671

Query: 672 SGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMPTEGE 731
           SGQAPK+SSRASVGA GPE  LVDVNVYLIIAICAVSSLLVLTLLLYT LRCSA PTEG 
Sbjct: 672 SGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGA 731

Query: 732 CAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCAGSTERTGEPSA 791
           C   KPTLVCSSAVGSWSYSQQRRQRVCSGEG  K DLMAFSP LSPC     +      
Sbjct: 732 CTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAENQDL 791

Query: 792 SSDSTGKV 799
           + D   KV
Sbjct: 792 NEDHDAKV 799


>gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score = 1192 bits (3083), Expect = 0.0
 Identities = 607/768 (79%), Positives = 668/768 (86%)

Query: 12  QPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGR 71
           Q LLL LL+LA W VGSGQLHYSVPEEA+HGTFVGRIAQDLGLELAELVPRLF++ SK R
Sbjct: 12  QCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDR 71

Query: 72  GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPP 131
            DLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEV+DINDNPP
Sbjct: 72  EDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPP 131

Query: 132 VFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKP 191
           +FP  ++ + I ESR  DS FPLEGASDAD+G N++LTY+LS +EYF LDV  ++   K 
Sbjct: 132 LFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQ 191

Query: 192 LGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKL 251
           +GL+L+K LDREE P  +L LTATDGGKPELTGTVQLL+TVLD NDNAP F+++ Y V++
Sbjct: 192 IGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRI 251

Query: 252 PENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFE 311
            EN   GT VI  NASD DEG NG I YSF+S V+  +   F +D  +G I + G++DFE
Sbjct: 252 FENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFE 311

Query: 312 ESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIAL 371
           +   +KI ++A DKG PP+AGHCT+LV ++D NDN P++ + +LS+PV+EDAQ GTVIAL
Sbjct: 312 QENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIAL 371

Query: 372 ISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGG 431
           ISV DLD+ ANGQV CSLTPHVPFKLVST+KNYYSLVLD ALDRESVSAYELVVTARDGG
Sbjct: 372 ISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG 431

Query: 432 SPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVS 491
           SPSLWATA +SVEVAD+NDNAPAFAQ EYTVFVKENNPPGCHIFTVSARDADAQENALVS
Sbjct: 432 SPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVS 491

Query: 492 YSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL 551
           YSLVERR+GER+LSSY+SVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL
Sbjct: 492 YSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL 551

Query: 552 QVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLSYEL 611
           QVFVLDENDNAPALL PR+ GT GAVSE+V RS+GAG VV KVRAVDADSGYNAWLSYEL
Sbjct: 552 QVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSYEL 611

Query: 612 QPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVSLVE 671
           QP  +SA  PFRVGLYTGEISTTR LDE D+PR RLLVLVKDHGEPALTATATVLVSLVE
Sbjct: 612 QPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVE 671

Query: 672 SGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMPTEGE 731
           SGQAPK+SSRASVGA GPE  LVDVNVYLIIAICAVSSLLVLTLLLYT LRCSA PTEG 
Sbjct: 672 SGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGA 731

Query: 732 CAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPC 779
           C   KPTLVCSSAVGSWSYSQQRRQRVCSGEG  K DLMAFSP LSPC
Sbjct: 732 CTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPC 779


>gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo
           sapiens]
          Length = 844

 Score = 1191 bits (3081), Expect = 0.0
 Identities = 628/821 (76%), Positives = 683/821 (83%), Gaps = 5/821 (0%)

Query: 12  QPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGR 71
           Q LLLSLL+LA W VGSGQLHYSV EEA HGTFVGRIAQDLGLELAELV RLF++ SK  
Sbjct: 11  QCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASKRH 70

Query: 72  GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPP 131
           GDLLEVNLQNGILFVNSRIDREELCGRS ECSIHLEVIVDRPLQVFHVDVEVKDINDNPP
Sbjct: 71  GDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDNPP 130

Query: 132 VFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKP 191
            F  T++ L I ESR LDSRFPLEGASDAD+GENALLTY+LSPNEYF LD+     + K 
Sbjct: 131 RFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKDKF 190

Query: 192 LGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKL 251
             LVLRKLLDREE P+L LLLTATDGGKPE TG+V LLI VLD NDNAP+FDR +Y VK+
Sbjct: 191 PVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEVKM 250

Query: 252 PENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFE 311
            EN    TLVI  NASD DEG+N +++YSFSS V P I+ KF ++  +G I V   +DFE
Sbjct: 251 YENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAIDFE 310

Query: 312 ESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIAL 371
           +S  ++I V+  DKG PP+ GHCT+LVE++D NDN+P++ + +LS+PVKEDAQ+GTVIAL
Sbjct: 311 DSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVIAL 370

Query: 372 ISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGG 431
           ISV D D+ ANGQVTCSLTPHVPFKLVSTYKNYYSLVLD ALDRE VSAYELVVTARDGG
Sbjct: 371 ISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARDGG 430

Query: 432 SPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVS 491
           SP LWATA VSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSA DADAQENALVS
Sbjct: 431 SPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENALVS 490

Query: 492 YSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL 551
           YSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD GVPPLGSN+TL
Sbjct: 491 YSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNLTL 550

Query: 552 QVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLSYEL 611
           QVFVLDENDNAPALL        GAVSE+VLRSV AG VV KVRAVDADSGYNAWLSYEL
Sbjct: 551 QVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSYEL 610

Query: 612 QPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVSLVE 671
           Q     A IPFRVGLYTGEISTTRALDETD+PRQRLLVLVKDHGEP+LTATATVLVSLVE
Sbjct: 611 QSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSLVE 670

Query: 672 SGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMPTEGE 731
             QAPK+SSRASVG   PEV LVDVNVYLIIAICAVSSLLVLTLLLYT LRCSA PTEG 
Sbjct: 671 GSQAPKASSRASVG-VAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPTEGA 729

Query: 732 CAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCAGSTERTGEPSA 791
           C P KPTLVCSSAVGSWSYSQQRRQRVCSGEG  K DLMAFSP L PC        + S 
Sbjct: 730 CGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCPMVDVDGEDQSI 789

Query: 792 SSDSTGKVGFSSILFIYIIFFLERY--YRLLPGAVQIVLFI 830
             D + KVG+   +FI+++ F+     YR+     Q + F+
Sbjct: 790 GGDHSRKVGY--YVFIFLLCFMNNIFSYRIFSNMYQNISFL 828


>gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo
           sapiens]
          Length = 814

 Score = 1185 bits (3066), Expect = 0.0
 Identities = 612/799 (76%), Positives = 673/799 (84%)

Query: 1   MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60
           M Y  RG+     LLL LL+LA W VGSGQLHYSVPEEA+HGTFVGRIAQDLGLELAELV
Sbjct: 1   MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLF++ SK   DLLEV+LQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD
Sbjct: 61  PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120

Query: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180
           VEVKD+NDNPPVF    + LF++ESR  DSRFPLEGASDAD+G N++LTYRLS ++YF L
Sbjct: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180

Query: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240
           DV + N + K + LVLRK LDRE+ P  HL LTATDGGKPELTGTVQLL+TVLD NDNAP
Sbjct: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240

Query: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300
            F+++ Y V++ EN   GT VI  NASD DEG NG I YSF+S V   +   F +D  +G
Sbjct: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300

Query: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360
            I + G++DFE+   +KI ++A DKG PP+AGHCT+LV ++D NDN P++ + +LS+PV+
Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360

Query: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420
           EDAQ GTVIALISV DLD+ ANGQVTCSL PHVPFKLVST+KNYYSLVLD ALDRE VSA
Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420

Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480
           YELVVTARDGGSPSLWATA +SVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSAR
Sbjct: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQENALVSYSLVERR+GERSLSSY+SVH ESGKVYALQPLDHEELELLQFQVSARDA
Sbjct: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL PR+ GT GA S++V RSVGAG VV KVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660
           SGYNAWLSYELQP  +S  IPFRVGLYTGEISTTR LDE D+PR RLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660

Query: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720
           ATATVLVSLVESGQAPK+SSR S G  GPE  LVDVNVYLIIAICAVSSLLVLTLLLYT 
Sbjct: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780
           LRCSA+PTEG C  GKPTLVCSSAVGSWSYSQQ+ QRVCSGEG  KTDLMAFSP L P  
Sbjct: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL 780

Query: 781 GSTERTGEPSASSDSTGKV 799
           GS +   E   + D   KV
Sbjct: 781 GSVDVGEEQDLNVDHGLKV 799


>gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score = 1184 bits (3064), Expect = 0.0
 Identities = 610/794 (76%), Positives = 671/794 (84%)

Query: 1   MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60
           M Y  RG+     LLL LL+LA W VGSGQLHYSVPEEA+HGTFVGRIAQDLGLELAELV
Sbjct: 1   MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLF++ SK   DLLEV+LQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD
Sbjct: 61  PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120

Query: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180
           VEVKD+NDNPPVF    + LF++ESR  DSRFPLEGASDAD+G N++LTYRLS ++YF L
Sbjct: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180

Query: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240
           DV + N + K + LVLRK LDRE+ P  HL LTATDGGKPELTGTVQLL+TVLD NDNAP
Sbjct: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240

Query: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300
            F+++ Y V++ EN   GT VI  NASD DEG NG I YSF+S V   +   F +D  +G
Sbjct: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300

Query: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360
            I + G++DFE+   +KI ++A DKG PP+AGHCT+LV ++D NDN P++ + +LS+PV+
Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360

Query: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420
           EDAQ GTVIALISV DLD+ ANGQVTCSL PHVPFKLVST+KNYYSLVLD ALDRE VSA
Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420

Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480
           YELVVTARDGGSPSLWATA +SVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSAR
Sbjct: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQENALVSYSLVERR+GERSLSSY+SVH ESGKVYALQPLDHEELELLQFQVSARDA
Sbjct: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL PR+ GT GA S++V RSVGAG VV KVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660
           SGYNAWLSYELQP  +S  IPFRVGLYTGEISTTR LDE D+PR RLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660

Query: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720
           ATATVLVSLVESGQAPK+SSR S G  GPE  LVDVNVYLIIAICAVSSLLVLTLLLYT 
Sbjct: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780
           LRCSA+PTEG C  GKPTLVCSSAVGSWSYSQQ+ QRVCSGEG  KTDLMAFSP L P  
Sbjct: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL 780

Query: 781 GSTERTGEPSASSD 794
           GS +   E   + D
Sbjct: 781 GSVDVGEEQDLNVD 794


>gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens]
          Length = 936

 Score = 1181 bits (3055), Expect = 0.0
 Identities = 613/790 (77%), Positives = 671/790 (84%), Gaps = 1/790 (0%)

Query: 1   MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60
           M+YS RG   G  LLL  L+LA W  GSGQLHYS+PEEA+HGTFVGRIAQDLGLELAELV
Sbjct: 1   MVYSRRGSL-GSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59

Query: 61  PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLF++ SKGRGDLLEVNLQNGILFVNSRIDREELC R AECSIHLEVIVDRPLQVFHV+
Sbjct: 60  PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119

Query: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180
           V VKDINDNPP F   ++ LFI ESR  DSRFPLEGASD DIG NA L YRL+PNEYF L
Sbjct: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179

Query: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240
           DV T+ ++   L LVLRK LDREET E  LL+ ATDGGKPELTGTVQLLI VLD NDNAP
Sbjct: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239

Query: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300
            FD+++Y V+L EN   GTLVI  NASD DEG+N +I+Y FS+ V  D+KSKF ++  +G
Sbjct: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299

Query: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360
            I V G +D+E+  +++I ++A+DK   PL+GHC ++V+++DVNDN P++ I TL +PVK
Sbjct: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359

Query: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420
           EDA L TVIALISV D D+ ANGQVTCSL PHVPFKLVST+KNYYSLVLD ALDRESVS 
Sbjct: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419

Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480
           YELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQ +YTVFVKENNPPGCHIFTVSAR
Sbjct: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479

Query: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQENALVSYSLVERR+GER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDA
Sbjct: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL PR+ GT GAVSE+V RSVGAG VV KVRAVD D
Sbjct: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599

Query: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660
           SGYNAWLSYELQP   SA IPFRVGLYTGEISTTR+LDET+APR RLLVLVKDHGEP LT
Sbjct: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659

Query: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720
           ATATVLVSLVESGQAPK+SSRAS GA GPE  LVDVNVYLIIAICAVSSLLVLTLLLYT 
Sbjct: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719

Query: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780
           LRCSA PTE  C  GKPTL+CSSAVGSWSYSQQRRQRVCSGE   KTDLMAFSP L    
Sbjct: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGP 779

Query: 781 GSTERTGEPS 790
            ST+   +P+
Sbjct: 780 TSTDNPRQPN 789


>gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo
           sapiens]
          Length = 948

 Score = 1180 bits (3052), Expect = 0.0
 Identities = 616/768 (80%), Positives = 660/768 (85%), Gaps = 1/768 (0%)

Query: 12  QPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGR 71
           Q LLLSLL+LA W VGSGQLHYSV EEA HGTFVGRIAQDLGLELAELV RLF++ SK  
Sbjct: 11  QCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASKRH 70

Query: 72  GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPP 131
           GDLLEVNLQNGILFVNSRIDREELCGRS ECSIHLEVIVDRPLQVFHVDVEVKDINDNPP
Sbjct: 71  GDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDNPP 130

Query: 132 VFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKP 191
            F  T++ L I ESR LDSRFPLEGASDAD+GENALLTY+LSPNEYF LD+     + K 
Sbjct: 131 RFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKDKF 190

Query: 192 LGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKL 251
             LVLRKLLDREE P+L LLLTATDGGKPE TG+V LLI VLD NDNAP+FDR +Y VK+
Sbjct: 191 PVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEVKM 250

Query: 252 PENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFE 311
            EN    TLVI  NASD DEG+N +++YSFSS V P I+ KF ++  +G I V   +DFE
Sbjct: 251 YENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAIDFE 310

Query: 312 ESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIAL 371
           +S  ++I V+  DKG PP+ GHCT+LVE++D NDN+P++ + +LS+PVKEDAQ+GTVIAL
Sbjct: 311 DSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVIAL 370

Query: 372 ISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGG 431
           ISV D D+ ANGQVTCSLTPHVPFKLVSTYKNYYSLVLD ALDRE VSAYELVVTARDGG
Sbjct: 371 ISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARDGG 430

Query: 432 SPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVS 491
           SP LWATA VSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSA DADAQENALVS
Sbjct: 431 SPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENALVS 490

Query: 492 YSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL 551
           YSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD GVPPLGSN+TL
Sbjct: 491 YSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNLTL 550

Query: 552 QVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLSYEL 611
           QVFVLDENDNAPALL        GAVSE+VLRSV AG VV KVRAVDADSGYNAWLSYEL
Sbjct: 551 QVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSYEL 610

Query: 612 QPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVSLVE 671
           Q     A IPFRVGLYTGEISTTRALDETD+PRQRLLVLVKDHGEP+LTATATVLVSLVE
Sbjct: 611 QSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSLVE 670

Query: 672 SGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMPTEGE 731
             QAPK+SSRASVG   PEV LVDVNVYLIIAICAVSSLLVLTLLLYT LRCSA PTEG 
Sbjct: 671 GSQAPKASSRASVG-VAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPTEGA 729

Query: 732 CAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPC 779
           C P KPTLVCSSAVGSWSYSQQRRQRVCSGEG  K DLMAFSP L PC
Sbjct: 730 CGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPC 777


>gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo
           sapiens]
          Length = 816

 Score = 1178 bits (3048), Expect = 0.0
 Identities = 612/784 (78%), Positives = 668/784 (85%), Gaps = 1/784 (0%)

Query: 1   MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60
           M+YS RG   G  LLL  L+LA W  GSGQLHYS+PEEA+HGTFVGRIAQDLGLELAELV
Sbjct: 1   MVYSRRGSL-GSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59

Query: 61  PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLF++ SKGRGDLLEVNLQNGILFVNSRIDREELC R AECSIHLEVIVDRPLQVFHV+
Sbjct: 60  PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119

Query: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180
           V VKDINDNPP F   ++ LFI ESR  DSRFPLEGASD DIG NA L YRL+PNEYF L
Sbjct: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179

Query: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240
           DV T+ ++   L LVLRK LDREET E  LL+ ATDGGKPELTGTVQLLI VLD NDNAP
Sbjct: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239

Query: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300
            FD+++Y V+L EN   GTLVI  NASD DEG+N +I+Y FS+ V  D+KSKF ++  +G
Sbjct: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299

Query: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360
            I V G +D+E+  +++I ++A+DK   PL+GHC ++V+++DVNDN P++ I TL +PVK
Sbjct: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359

Query: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420
           EDA L TVIALISV D D+ ANGQVTCSL PHVPFKLVST+KNYYSLVLD ALDRESVS 
Sbjct: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419

Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480
           YELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQ +YTVFVKENNPPGCHIFTVSAR
Sbjct: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479

Query: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQENALVSYSLVERR+GER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDA
Sbjct: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL PR+ GT GAVSE+V RSVGAG VV KVRAVD D
Sbjct: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599

Query: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660
           SGYNAWLSYELQP   SA IPFRVGLYTGEISTTR+LDET+APR RLLVLVKDHGEP LT
Sbjct: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659

Query: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720
           ATATVLVSLVESGQAPK+SSRAS GA GPE  LVDVNVYLIIAICAVSSLLVLTLLLYT 
Sbjct: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719

Query: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780
           LRCSA PTE  C  GKPTL+CSSAVGSWSYSQQRRQRVCSGE   KTDLMAFSP L    
Sbjct: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGP 779

Query: 781 GSTE 784
            ST+
Sbjct: 780 TSTD 783


>gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo
           sapiens]
          Length = 824

 Score = 1174 bits (3037), Expect = 0.0
 Identities = 609/805 (75%), Positives = 679/805 (84%), Gaps = 2/805 (0%)

Query: 15  LLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGRGDL 74
           LLSLL+LA W VGSGQL YSVPEEA+HGTFVGRIAQDLGLEL ELVPRLF++ SK  GDL
Sbjct: 15  LLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDL 74

Query: 75  LEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPPVFP 134
           LEVNLQNGILFVNSRIDREELCGRSAECSIH+EVIVDRPLQVFHV+VEVKDINDNPP+FP
Sbjct: 75  LEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDNPPIFP 134

Query: 135 ATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLGL 194
            T K +   ESR LDSRFPLEGASDADIG NALL+Y+LS +E+FFLD+  +++  + L L
Sbjct: 135 MTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELSESLSL 194

Query: 195 VLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPEN 254
           VL K LDREET E++LLL ATDGGKPELTGTVQ+LI VLD NDN P F +++Y VKL EN
Sbjct: 195 VLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLEN 254

Query: 255 VSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEESR 314
            + GTLV+  NASD DEG N +I+YS  SDVS  I++KF +DP+SG I   G +D+EE++
Sbjct: 255 TANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAK 314

Query: 315 AHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIALISV 374
           +++I V A DKG P ++GHC + +++VD+NDN P+++I +LS+P+ E+A LGTVIALI+V
Sbjct: 315 SYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITV 374

Query: 375 IDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGGSPS 434
            D D+  NG VTCSLTPHVPFKLVST+KNYYSLVLD ALDRESVSAYELVVTARDGGSPS
Sbjct: 375 SDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434

Query: 435 LWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSL 494
           LWAT  VS+EVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQENALVSYSL
Sbjct: 435 LWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494

Query: 495 VERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVF 554
           VERR+GER+LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLGSNVTLQVF
Sbjct: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVF 554

Query: 555 VLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLSYELQPE 614
           VLDENDNAPALL PR     GAVSE+V  SVGAG VV KVRAVDADSGYNAWLSYELQ  
Sbjct: 555 VLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLG 614

Query: 615 TASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVSLVESGQ 674
           T SA IPFRVGLYTGEISTTRALDE D+PR RLLVLVKDHGEPALTATATVLVSLVESGQ
Sbjct: 615 TGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674

Query: 675 APKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMPTEGECAP 734
           APK+SSRA VGA G E TLVDVNVYLIIAICAVSSLLVLT+LLYT LRCS  PTEG  AP
Sbjct: 675 APKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTEGARAP 734

Query: 735 GKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCAGSTERTGEPSASSD 794
           GKPTLVCSSAVGSWSYSQQRRQRVCSGE   KTDLMAFSP LS    S E   +  + S+
Sbjct: 735 GKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAEE--KQLSESE 792

Query: 795 STGKVGFSSILFIYIIFFLERYYRL 819
             GKV     L    I   +++Y +
Sbjct: 793 YVGKVSLLLFLANSKIVLFKKFYMI 817


>gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens]
          Length = 948

 Score = 1170 bits (3026), Expect = 0.0
 Identities = 605/784 (77%), Positives = 671/784 (85%), Gaps = 2/784 (0%)

Query: 15  LLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGRGDL 74
           LLSLL+LA W VGSGQL YSVPEEA+HGTFVGRIAQDLGLEL ELVPRLF++ SK  GDL
Sbjct: 15  LLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDL 74

Query: 75  LEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPPVFP 134
           LEVNLQNGILFVNSRIDREELCGRSAECSIH+EVIVDRPLQVFHV+VEVKDINDNPP+FP
Sbjct: 75  LEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDNPPIFP 134

Query: 135 ATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLGL 194
            T K +   ESR LDSRFPLEGASDADIG NALL+Y+LS +E+FFLD+  +++  + L L
Sbjct: 135 MTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELSESLSL 194

Query: 195 VLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPEN 254
           VL K LDREET E++LLL ATDGGKPELTGTVQ+LI VLD NDN P F +++Y VKL EN
Sbjct: 195 VLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLEN 254

Query: 255 VSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEESR 314
            + GTLV+  NASD DEG N +I+YS  SDVS  I++KF +DP+SG I   G +D+EE++
Sbjct: 255 TANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAK 314

Query: 315 AHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIALISV 374
           +++I V A DKG P ++GHC + +++VD+NDN P+++I +LS+P+ E+A LGTVIALI+V
Sbjct: 315 SYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITV 374

Query: 375 IDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGGSPS 434
            D D+  NG VTCSLTPHVPFKLVST+KNYYSLVLD ALDRESVSAYELVVTARDGGSPS
Sbjct: 375 SDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434

Query: 435 LWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSL 494
           LWAT  VS+EVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQENALVSYSL
Sbjct: 435 LWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494

Query: 495 VERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVF 554
           VERR+GER+LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLGSNVTLQVF
Sbjct: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVF 554

Query: 555 VLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLSYELQPE 614
           VLDENDNAPALL PR     GAVSE+V  SVGAG VV KVRAVDADSGYNAWLSYELQ  
Sbjct: 555 VLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLG 614

Query: 615 TASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVSLVESGQ 674
           T SA IPFRVGLYTGEISTTRALDE D+PR RLLVLVKDHGEPALTATATVLVSLVESGQ
Sbjct: 615 TGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674

Query: 675 APKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMPTEGECAP 734
           APK+SSRA VGA G E TLVDVNVYLIIAICAVSSLLVLT+LLYT LRCS  PTEG  AP
Sbjct: 675 APKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTEGARAP 734

Query: 735 GKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCAGSTERTGEPSASSD 794
           GKPTLVCSSAVGSWSYSQQRRQRVCSGE   KTDLMAFSP LS    S E   +  + S+
Sbjct: 735 GKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAEE--KQLSESE 792

Query: 795 STGK 798
             GK
Sbjct: 793 YVGK 796


>gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo
           sapiens]
          Length = 810

 Score = 1160 bits (3002), Expect = 0.0
 Identities = 604/792 (76%), Positives = 668/792 (84%), Gaps = 3/792 (0%)

Query: 14  LLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGRGD 73
           L L LL+L  W VGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLF++ SK  GD
Sbjct: 14  LQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRVASKTHGD 73

Query: 74  LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPPVF 133
           LLEVNLQNGILFVNSRIDREELCG+SAECSIHLEVIVDRPLQVFHV+VEVKDINDNPPVF
Sbjct: 74  LLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDINDNPPVF 133

Query: 134 PATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLG 193
              ++ L IAES+  DSRFPLEGASDADI ENALLTYRLS NEYF LD PT+ +Q+K L 
Sbjct: 134 SLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNGKQIKRLS 193

Query: 194 LVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPE 253
           L+L+K LDRE+TPEL+LLLTATDGGKPELTGTV+LL+ VLD NDN P FD++ Y V L E
Sbjct: 194 LILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSEYKVSLME 253

Query: 254 NVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEES 313
           N +  TLV+  NA+D DEG+NG++ YS  S + P+ +  F +D  +G + V G +D+EE+
Sbjct: 254 NAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVNGTLDYEEN 312

Query: 314 RAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIALIS 373
           + +KI V+A DKG PP+AGHCT+ VE++D NDN+P++ + +LS+PV+EDAQ  TVIALIS
Sbjct: 313 KFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPSTVIALIS 372

Query: 374 VIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGGSP 433
           V D D+  NGQVTCSLTPHVPFKLVST+KNYYSLVLD ALDRE+V AYELVVTARDGGSP
Sbjct: 373 VSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVTARDGGSP 432

Query: 434 SLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYS 493
           SLWATARVSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSARDADAQENALVSYS
Sbjct: 433 SLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYS 492

Query: 494 LVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQV 553
           LVERRLG+R+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL SNVTLQV
Sbjct: 493 LVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLSSNVTLQV 552

Query: 554 FVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLSYELQP 613
           FVLDENDNAPALL  +     GAV+++V RSVGAG VV KVRAVDADSGYNAWLSYELQP
Sbjct: 553 FVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQP 612

Query: 614 ETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVSLVESG 673
               + IPFRVGLYTGEISTTRALDE D+PR RLLVLVKDHGEPALTATATVLVSLVESG
Sbjct: 613 AAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESG 672

Query: 674 QAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMPTEGECA 733
           QAPK+SSR   GA  PE  LVDVNVYLIIAIC VSSLLVLTLLLYT L  SA PTEG CA
Sbjct: 673 QAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSATPTEGACA 732

Query: 734 PGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCAGSTERTGE-PSAS 792
           PGKPTLVCS AVGSWSYSQQRRQRVCS EG  KTDLMAFSP L P   + E  GE     
Sbjct: 733 PGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSL-PLGLNKEEEGERQEPG 791

Query: 793 SDSTGKVGFSSI 804
           S+  G+V F  I
Sbjct: 792 SNHPGQVSFLQI 803


>gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo
           sapiens]
          Length = 949

 Score = 1157 bits (2994), Expect = 0.0
 Identities = 599/775 (77%), Positives = 661/775 (85%), Gaps = 2/775 (0%)

Query: 14  LLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGRGD 73
           L L LL+L  W VGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLF++ SK  GD
Sbjct: 14  LQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRVASKTHGD 73

Query: 74  LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPPVF 133
           LLEVNLQNGILFVNSRIDREELCG+SAECSIHLEVIVDRPLQVFHV+VEVKDINDNPPVF
Sbjct: 74  LLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDINDNPPVF 133

Query: 134 PATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLG 193
              ++ L IAES+  DSRFPLEGASDADI ENALLTYRLS NEYF LD PT+ +Q+K L 
Sbjct: 134 SLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNGKQIKRLS 193

Query: 194 LVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPE 253
           L+L+K LDRE+TPEL+LLLTATDGGKPELTGTV+LL+ VLD NDN P FD++ Y V L E
Sbjct: 194 LILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSEYKVSLME 253

Query: 254 NVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEES 313
           N +  TLV+  NA+D DEG+NG++ YS  S + P+ +  F +D  +G + V G +D+EE+
Sbjct: 254 NAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVNGTLDYEEN 312

Query: 314 RAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIALIS 373
           + +KI V+A DKG PP+AGHCT+ VE++D NDN+P++ + +LS+PV+EDAQ  TVIALIS
Sbjct: 313 KFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPSTVIALIS 372

Query: 374 VIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGGSP 433
           V D D+  NGQVTCSLTPHVPFKLVST+KNYYSLVLD ALDRE+V AYELVVTARDGGSP
Sbjct: 373 VSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVTARDGGSP 432

Query: 434 SLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYS 493
           SLWATARVSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSARDADAQENALVSYS
Sbjct: 433 SLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYS 492

Query: 494 LVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQV 553
           LVERRLG+R+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL SNVTLQV
Sbjct: 493 LVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLSSNVTLQV 552

Query: 554 FVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLSYELQP 613
           FVLDENDNAPALL  +     GAV+++V RSVGAG VV KVRAVDADSGYNAWLSYELQP
Sbjct: 553 FVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQP 612

Query: 614 ETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVSLVESG 673
               + IPFRVGLYTGEISTTRALDE D+PR RLLVLVKDHGEPALTATATVLVSLVESG
Sbjct: 613 AAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESG 672

Query: 674 QAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMPTEGECA 733
           QAPK+SSR   GA  PE  LVDVNVYLIIAIC VSSLLVLTLLLYT L  SA PTEG CA
Sbjct: 673 QAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSATPTEGACA 732

Query: 734 PGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCAGSTERTGE 788
           PGKPTLVCS AVGSWSYSQQRRQRVCS EG  KTDLMAFSP L P   + E  GE
Sbjct: 733 PGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSL-PLGLNKEEEGE 786


>gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo
           sapiens]
          Length = 792

 Score = 1150 bits (2975), Expect = 0.0
 Identities = 599/768 (77%), Positives = 648/768 (84%)

Query: 9   PEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDS 68
           P  Q LLLSLL+LA W VGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELVPRLF++ S
Sbjct: 9   PGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68

Query: 69  KGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIND 128
           K  GDLLEVNLQNGILFVNSRIDRE+LCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIND
Sbjct: 69  KRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIND 128

Query: 129 NPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQ 188
           NPPVF   ++ + ++ES PLDS FPLEGASDADIG N+LLTY LS NE F L + T   +
Sbjct: 129 NPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDK 188

Query: 189 VKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYT 248
                LVLRKLLDRE+TP+L+LLL   DGGKPELTG+VQ+ ITVLD NDN P FD+  Y 
Sbjct: 189 SILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYK 248

Query: 249 VKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHM 308
           V L ENV   T VI  NASD DEGLNG+I Y     +    K  F ++P +G I + G +
Sbjct: 249 VVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGEL 308

Query: 309 DFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTV 368
           DFEE+ A++I V A+DKG P +AGH  +LVEV+DVNDN P++ + +LS+PV+EDAQ+GTV
Sbjct: 309 DFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTV 368

Query: 369 IALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTAR 428
           IALISV D D+ ANGQV CSLTPHVPFKLVSTYKNYYSLVLD ALDRESVSAYELVVTAR
Sbjct: 369 IALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTAR 428

Query: 429 DGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENA 488
           DGGSPSLWATARVSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQ+NA
Sbjct: 429 DGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNA 488

Query: 489 LVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548
           LVSYSLVERR+GE +LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN
Sbjct: 489 LVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548

Query: 549 VTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLS 608
           VTLQVFVLDENDNAPALL        GAVSE+V RSVGAG VV KVRAVDADSGYNAWLS
Sbjct: 549 VTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLS 608

Query: 609 YELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVS 668
           YELQP    A IPF VGLYTGEISTTR LDE DAPR RLLVLVKDHGEPALT+TATVLVS
Sbjct: 609 YELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLVS 668

Query: 669 LVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMPT 728
           LVE+GQAPK+SSRASVGA  PE  LVD+NVYLIIAICAVSSLLVLTLLLYT LRCSA PT
Sbjct: 669 LVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728

Query: 729 EGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGL 776
              CAPGKPTLVCSSAVGSWSYSQQRRQRVCS E   KTDLMAFSP L
Sbjct: 729 VSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776


>gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo
           sapiens]
          Length = 941

 Score = 1150 bits (2975), Expect = 0.0
 Identities = 599/768 (77%), Positives = 648/768 (84%)

Query: 9   PEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDS 68
           P  Q LLLSLL+LA W VGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELVPRLF++ S
Sbjct: 9   PGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68

Query: 69  KGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIND 128
           K  GDLLEVNLQNGILFVNSRIDRE+LCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIND
Sbjct: 69  KRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIND 128

Query: 129 NPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQ 188
           NPPVF   ++ + ++ES PLDS FPLEGASDADIG N+LLTY LS NE F L + T   +
Sbjct: 129 NPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDK 188

Query: 189 VKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYT 248
                LVLRKLLDRE+TP+L+LLL   DGGKPELTG+VQ+ ITVLD NDN P FD+  Y 
Sbjct: 189 SILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYK 248

Query: 249 VKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHM 308
           V L ENV   T VI  NASD DEGLNG+I Y     +    K  F ++P +G I + G +
Sbjct: 249 VVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGEL 308

Query: 309 DFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTV 368
           DFEE+ A++I V A+DKG P +AGH  +LVEV+DVNDN P++ + +LS+PV+EDAQ+GTV
Sbjct: 309 DFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTV 368

Query: 369 IALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTAR 428
           IALISV D D+ ANGQV CSLTPHVPFKLVSTYKNYYSLVLD ALDRESVSAYELVVTAR
Sbjct: 369 IALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTAR 428

Query: 429 DGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENA 488
           DGGSPSLWATARVSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQ+NA
Sbjct: 429 DGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNA 488

Query: 489 LVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548
           LVSYSLVERR+GE +LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN
Sbjct: 489 LVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548

Query: 549 VTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLS 608
           VTLQVFVLDENDNAPALL        GAVSE+V RSVGAG VV KVRAVDADSGYNAWLS
Sbjct: 549 VTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLS 608

Query: 609 YELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVS 668
           YELQP    A IPF VGLYTGEISTTR LDE DAPR RLLVLVKDHGEPALT+TATVLVS
Sbjct: 609 YELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLVS 668

Query: 669 LVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMPT 728
           LVE+GQAPK+SSRASVGA  PE  LVD+NVYLIIAICAVSSLLVLTLLLYT LRCSA PT
Sbjct: 669 LVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728

Query: 729 EGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGL 776
              CAPGKPTLVCSSAVGSWSYSQQRRQRVCS E   KTDLMAFSP L
Sbjct: 729 VSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776


>gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo
           sapiens]
          Length = 685

 Score =  792 bits (2045), Expect = 0.0
 Identities = 410/523 (78%), Positives = 449/523 (85%)

Query: 12  QPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGR 71
           Q LLLSLL+LA W VGSGQLHYSV EEA HGTFVGRIAQDLGLELAELV RLF++ SK  
Sbjct: 11  QCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASKRH 70

Query: 72  GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPP 131
           GDLLEVNLQNGILFVNSRIDREELCGRS ECSIHLEVIVDRPLQVFHVDVEVKDINDNPP
Sbjct: 71  GDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDNPP 130

Query: 132 VFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKP 191
            F  T++ L I ESR LDSRFPLEGASDAD+GENALLTY+LSPNEYF LD+     + K 
Sbjct: 131 RFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKDKF 190

Query: 192 LGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKL 251
             LVLRKLLDREE P+L LLLTATDGGKPE TG+V LLI VLD NDNAP+FDR +Y VK+
Sbjct: 191 PVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEVKM 250

Query: 252 PENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFE 311
            EN    TLVI  NASD DEG+N +++YSFSS V P I+ KF ++  +G I V   +DFE
Sbjct: 251 YENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAIDFE 310

Query: 312 ESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIAL 371
           +S  ++I V+  DKG PP+ GHCT+LVE++D NDN+P++ + +LS+PVKEDAQ+GTVIAL
Sbjct: 311 DSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVIAL 370

Query: 372 ISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGG 431
           ISV D D+ ANGQVTCSLTPHVPFKLVSTYKNYYSLVLD ALDRE VSAYELVVTARDGG
Sbjct: 371 ISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARDGG 430

Query: 432 SPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVS 491
           SP LWATA VSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSA DADAQENALVS
Sbjct: 431 SPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENALVS 490

Query: 492 YSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQ 534
           YSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQ
Sbjct: 491 YSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQ 533



 Score =  134 bits (336), Expect = 5e-31
 Identities = 100/341 (29%), Positives = 155/341 (45%), Gaps = 21/341 (6%)

Query: 338 VEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKL 397
           VEV D+NDN P+ ++    + + E   L +   L    D D   N  +T  L+P+  F L
Sbjct: 120 VEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVL 179

Query: 398 VSTYKN----YYSLVLDRALDRESVSAYELVVTARDGGSPSLWATARVSVEVADVNDNAP 453
               K     +  LVL + LDRE     +L++TA DGG P    +  + + V D NDNAP
Sbjct: 180 DIINKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAP 239

Query: 454 AFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRLGERSLSSYVSVHAE 513
            F +  Y V + EN      +  ++A D+D   N  + YS     L   ++     ++  
Sbjct: 240 IFDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSS--LVPPTIRRKFWINER 297

Query: 514 SGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLTPRMRGT 573
           +G++     +D E+    +  V   D G PP+  + T+ V +LDENDN+P ++       
Sbjct: 298 TGEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVT----- 352

Query: 574 DGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLSYELQPETASASIPFR-VGLYTGEIS 632
             ++S  V      G V+  +   D DSG N  ++  L P      +PF+ V  Y    S
Sbjct: 353 --SLSLPVKEDAQVGTVIALISVSDHDSGANGQVTCSLTPH-----VPFKLVSTYKNYYS 405

Query: 633 TT--RALDETDAPRQRLLVLVKDHGEPALTATATVLVSLVE 671
                ALD        L+V  +D G P L ATA+V V + +
Sbjct: 406 LVLDSALDRERVSAYELVVTARDGGSPPLWATASVSVEVAD 446



 Score =  132 bits (333), Expect = 1e-30
 Identities = 112/387 (28%), Positives = 178/387 (45%), Gaps = 18/387 (4%)

Query: 230 ITVLDNNDNAPVFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSD--VSP 287
           + V D NDN P F  T   + +PE+  + +      ASD D G N  + Y  S +     
Sbjct: 120 VEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVL 179

Query: 288 DIKSKFHMDPLSGAITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNA 347
           DI +K   D     + +   +D EE+   K+ + A D G P   G  +LL+ V+D NDNA
Sbjct: 180 DIINKKDKDKFP-VLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNA 238

Query: 348 PQLTIKTLSVPVKEDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTY---KNY 404
           P        V + E+    T++  ++  D D   N ++  S +  VP  +   +   +  
Sbjct: 239 PIFDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERT 298

Query: 405 YSLVLDRALDRESVSAYELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFV 464
             + ++ A+D E  + YE+ V   D G+P +     V VE+ D NDN+P    +  ++ V
Sbjct: 299 GEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPV 358

Query: 465 KENNPPGCHIFTVSARDADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLD 524
           KE+   G  I  +S  D D+  N  V+ SL    +  + +S+Y + ++    +     LD
Sbjct: 359 KEDAQVGTVIALISVSDHDSGANGQVTCSLTPH-VPFKLVSTYKNYYS----LVLDSALD 413

Query: 525 HEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRS 584
            E +   +  V+ARD G PPL +  ++ V V D NDNAPA             +  V  +
Sbjct: 414 RERVSAYELVVTARDGGSPPLWATASVSVEVADVNDNAPAF-------AQSEYTVFVKEN 466

Query: 585 VGAGVVVGKVRAVDADSGYNAWLSYEL 611
              G  +  V A DAD+  NA +SY L
Sbjct: 467 NPPGCHIFTVSAWDADAQENALVSYSL 493



 Score = 90.9 bits (224), Expect = 4e-18
 Identities = 82/272 (30%), Positives = 118/272 (43%), Gaps = 19/272 (6%)

Query: 441 VSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRLG 500
           V VEV D+NDN P F+ +E  + + E+           A DAD  ENAL++Y L      
Sbjct: 118 VDVEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYF 177

Query: 501 ERSLSSYVSVHAESGKVYALQPL-DHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDEN 559
              + +      +   V  L+ L D EE   L+  ++A D G P    +V+L + VLD N
Sbjct: 178 VLDIIN--KKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDAN 235

Query: 560 DNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLSYE---LQPETA 616
           DNAP    P          +M    V   +V+ ++ A D+D G N  + Y    L P T 
Sbjct: 236 DNAPIFDRPVYE------VKMYENQVNQTLVI-RLNASDSDEGINKEMMYSFSSLVPPTI 288

Query: 617 SASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVSLVESGQAP 676
                F +   TGEI    A+D  D+    + V V D G P +    TVLV L++     
Sbjct: 289 RRK--FWINERTGEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNS 346

Query: 677 KSSSRASVGATGPEVTLVDVNVYLIIAICAVS 708
                 S+     E    D  V  +IA+ +VS
Sbjct: 347 PEVIVTSLSLPVKE----DAQVGTVIALISVS 374


>gi|14165402 protocadherin alpha 1 isoform 3 precursor [Homo
           sapiens]
          Length = 686

 Score =  791 bits (2042), Expect = 0.0
 Identities = 399/534 (74%), Positives = 461/534 (86%)

Query: 1   MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60
           M++S RG    + LLL LL+LA W VGSGQLHYS+PEEA+HGTFVGR+AQDLGLELAELV
Sbjct: 1   MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60

Query: 61  PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120
           PRLF++ SK   DLLEVNLQNGILFVNSRIDREELC  SAECSIHLE+I DRPLQVFHV+
Sbjct: 61  PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120

Query: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180
           V+VKDINDNPPVF   ++ +FI ESR L+SRFP+EGA+DADIG NALLTY LSP++YF L
Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180

Query: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240
           DV  S++  K L L LRK LDREETPELHLLLTATDGGKPEL GTV+LLITVLD NDNAP
Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240

Query: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300
           +FD+ +Y V L E  + GTLV   NASD DEG+NG++++SF S +S DI+ KF +D  SG
Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300

Query: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360
            I +I  +D+EE+++++I V+AVDKG PP++ HC +LV+V+DVNDNAP+L + +L +P++
Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360

Query: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420
           EDA L TVIALI+V D D+ ANGQVTCSL PHVPFKLVST+KNYYSLVLD ALDRES+S 
Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420

Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480
           YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSAR
Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQ 534
           DADAQENALVSYSLVERR+GER+LS+YVSVHAESGKVYALQPLDHEELELLQFQ
Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQ 534



 Score =  147 bits (370), Expect = 5e-35
 Identities = 132/433 (30%), Positives = 200/433 (46%), Gaps = 37/433 (8%)

Query: 194 LVLRKLLDREETPE------LHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLY 247
           L +   +DREE  +      +HL L A    +P     V+  + V D NDN PVF     
Sbjct: 84  LFVNSRIDREELCQWSAECSIHLELIAD---RPLQVFHVE--VKVKDINDNPPVFRGREQ 138

Query: 248 TVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSD--VSPDIKSKFHMDPLSGAI--T 303
            + +PE+  + +      A+D D G N  + Y+ S     S D+++    D LS ++   
Sbjct: 139 IIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSLDVEAS---DELSKSLWLE 195

Query: 304 VIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDA 363
           +  ++D EE+    + + A D G P L G   LL+ V+DVNDNAP        V + E  
Sbjct: 196 LRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAPLFDQAVYRVHLLETT 255

Query: 364 QLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYS---LVLDRALDRESVSA 420
             GT++  ++  D D   NG+V  S    +   +   +K   S   + L   LD E   +
Sbjct: 256 ANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSGEIRLIDKLDYEETKS 315

Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480
           YE+ V A D GSP +    +V V+V DVNDNAP  A +   + ++E+ P    I  ++  
Sbjct: 316 YEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIREDAPLSTVIALITVS 375

Query: 481 DADAQENALVSYSLVERRLGE--RSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSAR 538
           D D+  N  V+ SL+     +   +  +Y S+  +S        LD E L + +  V+AR
Sbjct: 376 DRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSA-------LDRESLSVYELVVTAR 428

Query: 539 DAGVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVD 598
           D G P L +   + V V D NDNAPA   P         +  V  +   G  +  V A D
Sbjct: 429 DGGSPSLWATARVSVEVADVNDNAPAFAQPE-------YTVFVKENNPPGCHIFTVSARD 481

Query: 599 ADSGYNAWLSYEL 611
           AD+  NA +SY L
Sbjct: 482 ADAQENALVSYSL 494



 Score =  144 bits (364), Expect = 3e-34
 Identities = 110/344 (31%), Positives = 158/344 (45%), Gaps = 27/344 (7%)

Query: 338 VEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKL 397
           V+V D+NDN P    +   + + E   L +   +    D D  AN  +T +L+P   F L
Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180

Query: 398 VSTYKNYYS----LVLDRALDRESVSAYELVVTARDGGSPSLWATARVSVEVADVNDNAP 453
                +  S    L L + LDRE      L++TA DGG P L  T  + + V DVNDNAP
Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240

Query: 454 AFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRLGERSLSSYVSVHAE 513
            F Q+ Y V + E    G  + T++A DAD   N  V +S        R +     V + 
Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGI--SRDIQEKFKVDSS 298

Query: 514 SGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLTPRMRGT 573
           SG++  +  LD+EE +  + QV A D G PP+ ++  + V VLD NDNAP L        
Sbjct: 299 SGEIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPEL-------- 350

Query: 574 DGAVSEMVL---RSVGAGVVVGKVRAVDADSGYNAWLSYELQPETASASIPFR-VGLYTG 629
             AV+ + L          V+  +   D DSG N  ++  L P      +PF+ V  +  
Sbjct: 351 --AVTSLYLPIREDAPLSTVIALITVSDRDSGANGQVTCSLMPH-----VPFKLVSTFKN 403

Query: 630 EISTT--RALDETDAPRQRLLVLVKDHGEPALTATATVLVSLVE 671
             S     ALD        L+V  +D G P+L ATA V V + +
Sbjct: 404 YYSLVLDSALDRESLSVYELVVTARDGGSPSLWATARVSVEVAD 447


>gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo
           sapiens]
          Length = 686

 Score =  781 bits (2017), Expect = 0.0
 Identities = 394/523 (75%), Positives = 449/523 (85%)

Query: 12  QPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGR 71
           Q LLL LL+LA W VGSGQLHYSVPEEA+HGTFVGRIAQDLGLELAELVPRLF++ SK R
Sbjct: 12  QCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDR 71

Query: 72  GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPP 131
            DLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEV+DINDNPP
Sbjct: 72  EDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPP 131

Query: 132 VFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKP 191
           +FP  ++ + I ESR  DS FPLEGASDAD+G N++LTY+LS +EYF LDV  ++   K 
Sbjct: 132 LFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQ 191

Query: 192 LGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKL 251
           +GL+L+K LDREE P  +L LTATDGGKPELTGTVQLL+TVLD NDNAP F+++ Y V++
Sbjct: 192 IGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRI 251

Query: 252 PENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFE 311
            EN   GT VI  NASD DEG NG I YSF+S V+  +   F +D  +G I + G++DFE
Sbjct: 252 FENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFE 311

Query: 312 ESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIAL 371
           +   +KI ++A DKG PP+AGHCT+LV ++D NDN P++ + +LS+PV+EDAQ GTVIAL
Sbjct: 312 QENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIAL 371

Query: 372 ISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGG 431
           ISV DLD+ ANGQV CSLTPHVPFKLVST+KNYYSLVLD ALDRESVSAYELVVTARDGG
Sbjct: 372 ISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG 431

Query: 432 SPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVS 491
           SPSLWATA +SVEVAD+NDNAPAFAQ EYTVFVKENNPPGCHIFTVSARDADAQENALVS
Sbjct: 432 SPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVS 491

Query: 492 YSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQ 534
           YSLVERR+GER+LSSY+SVHAESGKVYALQPLDHEELELLQFQ
Sbjct: 492 YSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQ 534



 Score =  155 bits (393), Expect = 1e-37
 Identities = 109/341 (31%), Positives = 161/341 (47%), Gaps = 21/341 (6%)

Query: 338 VEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIALISVIDLDADANGQVTCSLTPHVPF-- 395
           VEV D+NDN P   ++   V + E     +V  L    D D  +N  +T  L+    F  
Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180

Query: 396 --KLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGGSPSLWATARVSVEVADVNDNAP 453
             K+ S       L+L ++LDRE   A+ L +TA DGG P L  T ++ V V DVNDNAP
Sbjct: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240

Query: 454 AFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRLGERSLSSYVSVHAE 513
            F QSEY V + EN   G  +  ++A D D   N  +SYS     L    +  + S+   
Sbjct: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSF--NSLVAAMVIDHFSIDRN 298

Query: 514 SGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLTPRMRGT 573
           +G++     LD E+  L +  + A D G PP+  + T+ V +LD+NDN P +        
Sbjct: 299 TGEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALT----- 353

Query: 574 DGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLSYELQPETASASIPFR-VGLYTGEIS 632
             ++S  V      G V+  +   D DSG N  ++  L P      +PF+ V  +    S
Sbjct: 354 --SLSLPVREDAQFGTVIALISVNDLDSGANGQVNCSLTPH-----VPFKLVSTFKNYYS 406

Query: 633 TT--RALDETDAPRQRLLVLVKDHGEPALTATATVLVSLVE 671
                ALD        L+V  +D G P+L ATA++ V + +
Sbjct: 407 LVLDSALDRESVSAYELVVTARDGGSPSLWATASLSVEVAD 447



 Score =  150 bits (379), Expect = 5e-36
 Identities = 119/388 (30%), Positives = 178/388 (45%), Gaps = 20/388 (5%)

Query: 230 ITVLDNNDNAPVFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDI 289
           + V D NDN P+F      V + E+    ++     ASD D G N  + Y  SS     +
Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180

Query: 290 KSKFHMDPLSG-AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAP 348
             K + D      + +   +D EE+ AH + + A D G P L G   LLV V+DVNDNAP
Sbjct: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240

Query: 349 QLTIKTLSVPVKEDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTY---KNYY 405
                   V + E+A  GT +  ++  D D  ANG ++ S    V   ++  +   +N  
Sbjct: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300

Query: 406 SLVLDRALDRESVSAYELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVK 465
            +V+   LD E  + Y++++ A D G P +     V V + D NDN P  A +  ++ V+
Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360

Query: 466 ENNPPGCHIFTVSARDADAQENALVSYSLVERRLGE--RSLSSYVSVHAESGKVYALQPL 523
           E+   G  I  +S  D D+  N  V+ SL      +   +  +Y S+  +S        L
Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSA-------L 413

Query: 524 DHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLR 583
           D E +   +  V+ARD G P L +  +L V V D NDNAPA   P         +  V  
Sbjct: 414 DRESVSAYELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPE-------YTVFVKE 466

Query: 584 SVGAGVVVGKVRAVDADSGYNAWLSYEL 611
           +   G  +  V A DAD+  NA +SY L
Sbjct: 467 NNPPGCHIFTVSARDADAQENALVSYSL 494


>gi|14277677 protocadherin gamma subfamily C, 3 isoform 2 precursor
           [Homo sapiens]
          Length = 863

 Score =  593 bits (1528), Expect = e-169
 Identities = 336/814 (41%), Positives = 487/814 (59%), Gaps = 27/814 (3%)

Query: 18  LLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGRGDLLEV 77
           LL+L      S  +HY +PEE E G  VG +  +LGL+L  L  R F++ S       EV
Sbjct: 20  LLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFEV 79

Query: 78  NLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPPVFPATQ 137
           N + G +FVN R+DREELCG    C++ LE++V+ PL++F V+V ++DINDN P FP  +
Sbjct: 80  NRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQE 139

Query: 138 KNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLGLVLR 197
             L I+E+    +RFPLE A D D+G N+L TY LS NEYF L V T     K   LVL 
Sbjct: 140 MKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVLE 199

Query: 198 KLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPENVSI 257
           + LDRE  P L L+LTA DGG P L+ ++ + I VLD NDNAPVF+++LY  ++ E+   
Sbjct: 200 RALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAPS 259

Query: 258 GTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEESRAHK 317
           GT V+   A+DLDEG NG+IIYSF S     ++  F +D ++G +T+ G +DFE+++ H+
Sbjct: 260 GTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLHE 319

Query: 318 IPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIALISVIDL 377
           I ++A DKG  P   HC +LVEVVDVNDNAP++T+ ++  PV EDA LGTVIAL+SV DL
Sbjct: 320 IYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTDL 379

Query: 378 DADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGGSPSLWA 437
           DA  NG VTC + P +PF L S+ KNY++L     LDRE+V  Y L +TARD G+PSL A
Sbjct: 380 DAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLSA 439

Query: 438 TARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVER 497
              V V+V+D+NDN P  +QS Y V+++ENN PG  I  +S  D DA +NA +S+ L+E+
Sbjct: 440 LTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLEQ 499

Query: 498 RLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLD 557
                 +  Y +++ ++G V +L PLD+E+    +      D G P L +N+++ +FV D
Sbjct: 500 GAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVTD 559

Query: 558 ENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLSYELQPETAS 617
            NDNAP +L PR     G+  EM+ R   AG +V +V   DAD+G+NAWLSY L      
Sbjct: 560 RNDNAPQVLYPR---PGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSPNQ 616

Query: 618 ASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVSLVESGQAPK 677
           +   F +GL+TG+IST R + +TD+PRQ L VL+KD+GEP+L+ TAT+ VS+ E   +P+
Sbjct: 617 SL--FAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTE--DSPE 672

Query: 678 SSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLT---LLLYTVLRCS------AMPT 728
           + +    G + P     ++  YL++++  VS   V+T   ++++ V +          P 
Sbjct: 673 ARAEFPSG-SAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYRAPV 731

Query: 729 EGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCAG--STERT 786
                   P+L   +  G         Q   + + ++   L+      SP A   +T R+
Sbjct: 732 SSLYRTPGPSLHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQNTLRS 791

Query: 787 GEP-------SASSDSTGKVGFS-SILFIYIIFF 812
            +P        A S   G+V FS S L + ++F+
Sbjct: 792 CDPVFYRQVLGAESAPPGQVRFSKSCLTLLVLFY 825


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,769,826
Number of Sequences: 37866
Number of extensions: 1443025
Number of successful extensions: 9879
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 187
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 3024
Number of HSP's gapped (non-prelim): 697
length of query: 842
length of database: 18,247,518
effective HSP length: 111
effective length of query: 731
effective length of database: 14,044,392
effective search space: 10266450552
effective search space used: 10266450552
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.