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Search of human proteins with 7662046
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
(2715 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 5672 0.0
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [... 989 0.0
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s... 188 5e-47
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 185 5e-46
gi|210032580 SET domain containing 1B [Homo sapiens] 178 6e-44
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 162 4e-39
gi|55741677 SET domain containing 1A [Homo sapiens] 156 3e-37
gi|163965366 nascent polypeptide-associated complex alpha subuni... 133 3e-30
gi|47132519 Ras association and pleckstrin homology domains 1 is... 126 3e-28
gi|116284392 mucin 2 precursor [Homo sapiens] 125 7e-28
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 121 8e-27
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 119 4e-26
gi|110349719 titin isoform N2-A [Homo sapiens] 115 6e-25
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 114 1e-24
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 112 6e-24
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 112 6e-24
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 112 6e-24
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 112 6e-24
gi|160707881 formin 2 [Homo sapiens] 112 6e-24
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 111 8e-24
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 111 8e-24
gi|153792074 proline rich 12 [Homo sapiens] 105 5e-22
gi|110832843 TBP-associated factor 4 [Homo sapiens] 105 6e-22
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 103 2e-21
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 102 7e-21
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 101 1e-20
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 101 1e-20
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 101 1e-20
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 99 6e-20
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 97 2e-19
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 5672 bits (14714), Expect = 0.0
Identities = 2715/2715 (100%), Positives = 2715/2715 (100%)
Query: 1 MAAAAGGGSCPGPGSARGRFPGRPRGAGGGGGRGGRGNGAERVRVALRRGGGATGPGGAE 60
MAAAAGGGSCPGPGSARGRFPGRPRGAGGGGGRGGRGNGAERVRVALRRGGGATGPGGAE
Sbjct: 1 MAAAAGGGSCPGPGSARGRFPGRPRGAGGGGGRGGRGNGAERVRVALRRGGGATGPGGAE 60
Query: 61 PGEDTALLRLLGLRRGLRRLRRLWAGPRVQRGRGRGRGRGWGPSRGCVPEEESSDGESDE 120
PGEDTALLRLLGLRRGLRRLRRLWAGPRVQRGRGRGRGRGWGPSRGCVPEEESSDGESDE
Sbjct: 61 PGEDTALLRLLGLRRGLRRLRRLWAGPRVQRGRGRGRGRGWGPSRGCVPEEESSDGESDE 120
Query: 121 EEFQGFHSDEDVAPSSLRSALRSQRGRAPRGRGRKHKTTPLPPPRLADVAPTPPKTPARK 180
EEFQGFHSDEDVAPSSLRSALRSQRGRAPRGRGRKHKTTPLPPPRLADVAPTPPKTPARK
Sbjct: 121 EEFQGFHSDEDVAPSSLRSALRSQRGRAPRGRGRKHKTTPLPPPRLADVAPTPPKTPARK 180
Query: 181 RGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVV 240
RGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVV
Sbjct: 181 RGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVV 240
Query: 241 AEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGG 300
AEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGG
Sbjct: 241 AEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGG 300
Query: 301 LPFVIKFVSRAKKVKMGQLSLGLESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQK 360
LPFVIKFVSRAKKVKMGQLSLGLESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQK
Sbjct: 301 LPFVIKFVSRAKKVKMGQLSLGLESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQK 360
Query: 361 LDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPP 420
LDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPP
Sbjct: 361 LDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPP 420
Query: 421 STSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRA 480
STSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRA
Sbjct: 421 STSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRA 480
Query: 481 EREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVI 540
EREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVI
Sbjct: 481 EREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVI 540
Query: 541 KTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKR 600
KTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKR
Sbjct: 541 KTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKR 600
Query: 601 RSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLK 660
RSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLK
Sbjct: 601 RSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLK 660
Query: 661 IYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVS 720
IYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVS
Sbjct: 661 IYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVS 720
Query: 721 PHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGV 780
PHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGV
Sbjct: 721 PHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGV 780
Query: 781 GSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISDRG 840
GSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISDRG
Sbjct: 781 GSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISDRG 840
Query: 841 PVRSEDESVEAKRERPSGPESPVQGPRIKHVCRHAAVALGQARAMVPEDVPRLSALPLRD 900
PVRSEDESVEAKRERPSGPESPVQGPRIKHVCRHAAVALGQARAMVPEDVPRLSALPLRD
Sbjct: 841 PVRSEDESVEAKRERPSGPESPVQGPRIKHVCRHAAVALGQARAMVPEDVPRLSALPLRD 900
Query: 901 RQDLATEDTSSASETESVPSRSRRGKVEAAGPGGESEPTGSGGTLAHTPRRSLPSHHGKK 960
RQDLATEDTSSASETESVPSRSRRGKVEAAGPGGESEPTGSGGTLAHTPRRSLPSHHGKK
Sbjct: 901 RQDLATEDTSSASETESVPSRSRRGKVEAAGPGGESEPTGSGGTLAHTPRRSLPSHHGKK 960
Query: 961 MRMARCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQCCVYRKCDKIEARKMERLAKKG 1020
MRMARCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQCCVYRKCDKIEARKMERLAKKG
Sbjct: 961 MRMARCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQCCVYRKCDKIEARKMERLAKKG 1020
Query: 1021 RTIVKTLLPWDSDESPEASPGPPGPRRGAGAGGPREEVVAHPGPEEQDSLLQRKSARRCV 1080
RTIVKTLLPWDSDESPEASPGPPGPRRGAGAGGPREEVVAHPGPEEQDSLLQRKSARRCV
Sbjct: 1021 RTIVKTLLPWDSDESPEASPGPPGPRRGAGAGGPREEVVAHPGPEEQDSLLQRKSARRCV 1080
Query: 1081 KQRPSYDIFEDSDDSEPGGPPAPRRRTPRENELPLPEPEEQSRPRKPTLQPVLQLKARRR 1140
KQRPSYDIFEDSDDSEPGGPPAPRRRTPRENELPLPEPEEQSRPRKPTLQPVLQLKARRR
Sbjct: 1081 KQRPSYDIFEDSDDSEPGGPPAPRRRTPRENELPLPEPEEQSRPRKPTLQPVLQLKARRR 1140
Query: 1141 LDKDALAPGPFASFPNGWTGKQKSPDGVHRVRVDFKEDCDLENVWLMGGLSVLTSVPGGP 1200
LDKDALAPGPFASFPNGWTGKQKSPDGVHRVRVDFKEDCDLENVWLMGGLSVLTSVPGGP
Sbjct: 1141 LDKDALAPGPFASFPNGWTGKQKSPDGVHRVRVDFKEDCDLENVWLMGGLSVLTSVPGGP 1200
Query: 1201 PMVCLLCASKGLHELVFCQVCCDPFHPFCLEEAERPLPQHHDTWCCRRCKFCHVCGRKGR 1260
PMVCLLCASKGLHELVFCQVCCDPFHPFCLEEAERPLPQHHDTWCCRRCKFCHVCGRKGR
Sbjct: 1201 PMVCLLCASKGLHELVFCQVCCDPFHPFCLEEAERPLPQHHDTWCCRRCKFCHVCGRKGR 1260
Query: 1261 GSKHLLECERCRHAYHPACLGPSYPTRATRKRRHWICSACVRCKSCGATPGKNWDVEWSG 1320
GSKHLLECERCRHAYHPACLGPSYPTRATRKRRHWICSACVRCKSCGATPGKNWDVEWSG
Sbjct: 1261 GSKHLLECERCRHAYHPACLGPSYPTRATRKRRHWICSACVRCKSCGATPGKNWDVEWSG 1320
Query: 1321 DYSLCPRCTQLYEKGNYCPICTRCYEDNDYESKMMQCAQCDHWVHAKCEGLSDEDYEILS 1380
DYSLCPRCTQLYEKGNYCPICTRCYEDNDYESKMMQCAQCDHWVHAKCEGLSDEDYEILS
Sbjct: 1321 DYSLCPRCTQLYEKGNYCPICTRCYEDNDYESKMMQCAQCDHWVHAKCEGLSDEDYEILS 1380
Query: 1381 GLPDSVLYTCGPCAGAAQPRWREALSGALQGGLRQVLQGLLSSKVVGPLLLCTQCGPDGK 1440
GLPDSVLYTCGPCAGAAQPRWREALSGALQGGLRQVLQGLLSSKVVGPLLLCTQCGPDGK
Sbjct: 1381 GLPDSVLYTCGPCAGAAQPRWREALSGALQGGLRQVLQGLLSSKVVGPLLLCTQCGPDGK 1440
Query: 1441 QLHPGPCGLQAVSQRFEDGHYKSVHSFMEDMVGILMRHSEEGETPDRRAGGQMKGLLLKL 1500
QLHPGPCGLQAVSQRFEDGHYKSVHSFMEDMVGILMRHSEEGETPDRRAGGQMKGLLLKL
Sbjct: 1441 QLHPGPCGLQAVSQRFEDGHYKSVHSFMEDMVGILMRHSEEGETPDRRAGGQMKGLLLKL 1500
Query: 1501 LESAFGWFDAHDPKYWRRSTRLPNGVLPNAVLPPSLDHVYAQWRQQEPETPESGQPPGDP 1560
LESAFGWFDAHDPKYWRRSTRLPNGVLPNAVLPPSLDHVYAQWRQQEPETPESGQPPGDP
Sbjct: 1501 LESAFGWFDAHDPKYWRRSTRLPNGVLPNAVLPPSLDHVYAQWRQQEPETPESGQPPGDP 1560
Query: 1561 SAAFQGKDPAAFSHLEDPRQCALCLKYGDADSKEAGRLLYIGQNEWTHVNCAIWSAEVFE 1620
SAAFQGKDPAAFSHLEDPRQCALCLKYGDADSKEAGRLLYIGQNEWTHVNCAIWSAEVFE
Sbjct: 1561 SAAFQGKDPAAFSHLEDPRQCALCLKYGDADSKEAGRLLYIGQNEWTHVNCAIWSAEVFE 1620
Query: 1621 ENDGSLKNVHAAVARGRQMRCELCLKPGATVGCCLSSCLSNFHFMCARASYCIFQDDKKV 1680
ENDGSLKNVHAAVARGRQMRCELCLKPGATVGCCLSSCLSNFHFMCARASYCIFQDDKKV
Sbjct: 1621 ENDGSLKNVHAAVARGRQMRCELCLKPGATVGCCLSSCLSNFHFMCARASYCIFQDDKKV 1680
Query: 1681 FCQKHTDLLDGKEIVNPDGFDVLRRVYVDFEGINFKRKFLTGLEPDAINVLIGSIRIDSL 1740
FCQKHTDLLDGKEIVNPDGFDVLRRVYVDFEGINFKRKFLTGLEPDAINVLIGSIRIDSL
Sbjct: 1681 FCQKHTDLLDGKEIVNPDGFDVLRRVYVDFEGINFKRKFLTGLEPDAINVLIGSIRIDSL 1740
Query: 1741 GTLSDLSDCEGRLFPIGYQCSRLYWSTVDARRRCWYRCRILEYRPWGPREEPAHLEAAEE 1800
GTLSDLSDCEGRLFPIGYQCSRLYWSTVDARRRCWYRCRILEYRPWGPREEPAHLEAAEE
Sbjct: 1741 GTLSDLSDCEGRLFPIGYQCSRLYWSTVDARRRCWYRCRILEYRPWGPREEPAHLEAAEE 1800
Query: 1801 NQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSF 1860
NQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSF
Sbjct: 1801 NQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSF 1860
Query: 1861 SGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLA 1920
SGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLA
Sbjct: 1861 SGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLA 1920
Query: 1921 PRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDM 1980
PRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDM
Sbjct: 1921 PRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDM 1980
Query: 1981 EVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVT 2040
EVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVT
Sbjct: 1981 EVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVT 2040
Query: 2041 VVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAG 2100
VVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAG
Sbjct: 2041 VVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAG 2100
Query: 2101 DRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPT 2160
DRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPT
Sbjct: 2101 DRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPT 2160
Query: 2161 RTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPL 2220
RTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPL
Sbjct: 2161 RTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPL 2220
Query: 2221 PPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKR 2280
PPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKR
Sbjct: 2221 PPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKR 2280
Query: 2281 VSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRP 2340
VSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRP
Sbjct: 2281 VSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRP 2340
Query: 2341 GEPAGEESPGPLQERSPLLPLPEDGPPQVPDGPPDLLLESQWHHYSGEASSSEEEPPSPD 2400
GEPAGEESPGPLQERSPLLPLPEDGPPQVPDGPPDLLLESQWHHYSGEASSSEEEPPSPD
Sbjct: 2341 GEPAGEESPGPLQERSPLLPLPEDGPPQVPDGPPDLLLESQWHHYSGEASSSEEEPPSPD 2400
Query: 2401 DKENQAPKRTGPHLRFEISSEDGFSVEAESLEGAWRTLIEKVQEARGHARLRHLSFSGMS 2460
DKENQAPKRTGPHLRFEISSEDGFSVEAESLEGAWRTLIEKVQEARGHARLRHLSFSGMS
Sbjct: 2401 DKENQAPKRTGPHLRFEISSEDGFSVEAESLEGAWRTLIEKVQEARGHARLRHLSFSGMS 2460
Query: 2461 GARLLGIHHDAVIFLAEQLPGAQRCQHYKFRYHQQGEGQEEPPLNPHGAARAEVYLRKCT 2520
GARLLGIHHDAVIFLAEQLPGAQRCQHYKFRYHQQGEGQEEPPLNPHGAARAEVYLRKCT
Sbjct: 2461 GARLLGIHHDAVIFLAEQLPGAQRCQHYKFRYHQQGEGQEEPPLNPHGAARAEVYLRKCT 2520
Query: 2521 FDMFNFLASQHRVLPEGATCDEEEDEVQLRSTRRATSLELPMAMRFRHLKKTSKEAVGVY 2580
FDMFNFLASQHRVLPEGATCDEEEDEVQLRSTRRATSLELPMAMRFRHLKKTSKEAVGVY
Sbjct: 2521 FDMFNFLASQHRVLPEGATCDEEEDEVQLRSTRRATSLELPMAMRFRHLKKTSKEAVGVY 2580
Query: 2581 RSAIHGRGLFCKRNIDAGEMVIEYSGIVIRSVLTDKREKFYDGKGIGCYMFRMDDFDVVD 2640
RSAIHGRGLFCKRNIDAGEMVIEYSGIVIRSVLTDKREKFYDGKGIGCYMFRMDDFDVVD
Sbjct: 2581 RSAIHGRGLFCKRNIDAGEMVIEYSGIVIRSVLTDKREKFYDGKGIGCYMFRMDDFDVVD 2640
Query: 2641 ATMHGNAARFINHSCEPNCFSRVIHVEGQKHIVIFALRRILRGEELTYDYKFPIEDASNK 2700
ATMHGNAARFINHSCEPNCFSRVIHVEGQKHIVIFALRRILRGEELTYDYKFPIEDASNK
Sbjct: 2641 ATMHGNAARFINHSCEPNCFSRVIHVEGQKHIVIFALRRILRGEELTYDYKFPIEDASNK 2700
Query: 2701 LPCNCGAKRCRRFLN 2715
LPCNCGAKRCRRFLN
Sbjct: 2701 LPCNCGAKRCRRFLN 2715
>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo
sapiens]
Length = 3969
Score = 989 bits (2557), Expect = 0.0
Identities = 680/1930 (35%), Positives = 943/1930 (48%), Gaps = 298/1930 (15%)
Query: 331 QHEESWQDVPQRRVGSGQGGSPCWKKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEM 390
Q E Q +P+ R + + P Q + + + + ++ + + ++ +
Sbjct: 491 QASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGSRTTKKLST-L 549
Query: 391 MPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQ 450
A +++ + PPPPL P PPP P S S P PP P++ P LP+ P
Sbjct: 550 QSAPQQQTSSSPPPPLLTP---PPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQG 606
Query: 451 EEQEESPPPVVPATCSR-KRGRPPLTPSQRAEREAARAGP--EGTSPPTPTPSTATGGPP 507
+ + P T + R P S + +E P + PP TP
Sbjct: 607 KRKSILREPTFRWTSLKHSRSEPQYFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASG 666
Query: 508 EDSPTVAPKSTTF--LKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRP 565
+ A + F L + +F M + S +++ PR E + + P R
Sbjct: 667 FSASGTAASARLFSPLHSGTRFDMH----KRSPLLRAPRFTPSEAHSRIFESVTLPSNRT 722
Query: 566 PITTSPPVPQEP-------APVPSPPRAPT---------------PPSTPVPLPEKRRSI 603
TS +P+ S PR+P+ P TP SI
Sbjct: 723 SAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSI 782
Query: 604 LREP----------TFRWTSLTRELPPPPPAPPPPPAPSPPPAP-ATSSRRPLLLRAPQF 652
P TF SLT+ P S P P ++SS PL P F
Sbjct: 783 SVSPLATSALNPTFTFPSHSLTQSGESAEKNQRPRKQTSAPAEPFSSSSPTPLF---PWF 839
Query: 653 TPSEAHLKIYESVLTPPPLG----APEAPEPEPPPADDSPAEPEPRA------------- 695
TP + P L A ++ E + D E E +
Sbjct: 840 TPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEI 899
Query: 696 --------VGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQ 747
VGR + + ++ K + + +G + L A++T+
Sbjct: 900 QSSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTK 959
Query: 748 LLPQA-----------LPPPQPQLQPPPSPQQMPPLE---KARIAGVGSL-----PLSGV 788
+L + L P P L+ + P K + +GS+ L
Sbjct: 960 ILIKKGRGNLEKTNLDLGPTAPSLEKEKTLCLSTPSSSTVKHSTSSIGSMLAQADKLPMT 1019
Query: 789 EEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISDRGPVRSEDES 848
++++ SLLK+AK QL KI++ + K + +
Sbjct: 1020 DKRVASLLKKAKAQLCKIEKSKSLK-------------------------------QTDQ 1048
Query: 849 VEAKRERPSGPESPVQGPRIKHVCRHAAVALGQARAMVPEDVPRLSALPLRDRQ----DL 904
+A+ + E+ V+GPRIKHVCR AAVALG+ RA+ P+D+P LSALP +R+ +
Sbjct: 1049 PKAQGQESDSSETSVRGPRIKHVCRRAAVALGRKRAVFPDDMPTLSALPWEEREKILSSM 1108
Query: 905 ATEDTSSASETESVPSRSRRGKVEAAGPGGESEPTGSGGTLAHTPRRSLPSHHGKKMRMA 964
+D SS + +E A P +P T P+ P G++ R
Sbjct: 1109 GNDDKSSIAGSEDAEP--------LAPPIKPIKPV----TRNKAPQEP-PVKKGRRSR-- 1153
Query: 965 RCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQCCVYRKCDKIE-----------ARKM 1013
RCG C GC +DCG C NCLDKPKFGG N KKQCC RKC ++ A+ +
Sbjct: 1154 RCGQCPGCQVPEDCGVCTNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAV 1213
Query: 1014 ERLAKKGRT----------IVKTLLPWDSDESPEASPGP-PGPRRGAGAGGPREEV---- 1058
++ KK +T +VK ++ DS + P S P P++ + PR+ V
Sbjct: 1214 KKKEKKSKTSEKKDSKESSVVKNVV--DSSQKPTPSAREDPAPKKSSSEPPPRKPVEEKS 1271
Query: 1059 ----VAHPGPEEQDSLL--QRKSARRCVKQRPSYDIFEDSDDSEPGGPPAPRRRT--PRE 1110
V+ PGPE + + RKS+++ +P+ I + P P+ P++
Sbjct: 1272 EEGNVSAPGPESKQATTPASRKSSKQV--SQPALVIPPQPPTTGPPRKEVPKTTPSEPKK 1329
Query: 1111 NELPLPEP-EEQSRPRKPTLQPVLQLKARRRLDKDALAPGP------------FASFPNG 1157
+ P PE EQS+ +K +P + +K + K+ P P ++ NG
Sbjct: 1330 KQPPPPESGPEQSKQKKVAPRPSIPVKQK---PKEKEKPPPVNKQENAGTLNILSTLSNG 1386
Query: 1158 WTGKQKSP-DGVHRVRVDFKEDCDLENVWLMGGLSVLTSVPGGPPMVCLLCASKGLHELV 1216
+ KQK P DGVHR+RVDFKEDC+ ENVW MGGL +LTSVP P +VC LCAS G E V
Sbjct: 1387 NSSKQKIPADGVHRIRVDFKEDCEAENVWEMGGLGILTSVPITPRVVCFLCASSGHVEFV 1446
Query: 1217 FCQVCCDPFHPFCLEEAERPLPQHHDTWCCRRCKFCHVCGRKGRGSKHLLECERCRHAYH 1276
+CQVCC+PFH FCLEE ERPL + WCCRRCKFCHVCGR+ + +K LLEC +CR++YH
Sbjct: 1447 YCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATKQLLECNKCRNSYH 1506
Query: 1277 PACLGPSYPTRATRKRRHWICSACVRCKSCGAT-PGKNWDVEWSGDYSLCPRCTQLYEKG 1335
P CLGP+YPT+ T+K++ WIC+ CVRCKSCG+T PGK WD +WS D+SLC C +L+ KG
Sbjct: 1507 PECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHDFSLCHDCAKLFAKG 1566
Query: 1336 NYCPICTRCYEDNDYESKMMQCAQCDHWVHAKCEGLSDEDYEILSGLPDSVLYTCGPCAG 1395
N+CP+C +CY+D+DYESKMMQC +CD WVH+KCE LSDE YEILS LP+SV YTC C
Sbjct: 1567 NFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSDEMYEILSNLPESVAYTCVNCTE 1626
Query: 1396 AAQPRWREALSGALQGGLRQVLQGLLSSKVVGPLLLCTQC-------------------- 1435
WR AL LQ L+QVL LL+S+ LL Q
Sbjct: 1627 RHPAEWRLALEKELQISLKQVLTALLNSRTTSHLLRYRQAAKPPDLNPETEESIPSRSSP 1686
Query: 1436 -GPD-------GKQLHPGPCGLQAVSQRFEDGHYKSVHSFMEDMVGILMR--HSEEGETP 1485
GPD KQ P L+ V ++ + G+Y SV F +D+V I+ +S+ G+
Sbjct: 1687 EGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSVLEFSDDIVKIIQAAINSDGGQPE 1746
Query: 1486 DRRAGGQMKGLLLKLLESAFGWFDAHDPKYWRRSTRLPN-GVLPNAVLPPSLDHVYAQWR 1544
++A +K ++ +E F WF ++W + N G+LPNAVLPPSLDH YAQW+
Sbjct: 1747 IKKANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGMLPNAVLPPSLDHNYAQWQ 1806
Query: 1545 QQE-------------------------PETPESGQPPGDP--SAAFQGKDPAAFSH--- 1574
++E P++P PP P S +D +
Sbjct: 1807 EREENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPILSTDRSREDSPELNPPPG 1866
Query: 1575 LEDPRQCALCLKYGDADSKEAGRLLYIGQNEWTHVNCAIWSAEVFEENDGSLKNVHAAVA 1634
+ED RQCALCL YGD + +AGRLLYIGQNEWTHVNCA+WSAEVFE++DGSLKNVH AV
Sbjct: 1867 IEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSAEVFEDDDGSLKNVHMAVI 1926
Query: 1635 RGRQMRCELCLKPGATVGCCLSSCLSNFHFMCARASYCIFQDDKKVFCQKHTDLLDGKEI 1694
RG+Q+RCE C KPGATVGCCL+SC SN+HFMC+RA C+F DDKKV+CQ+H DL+ G E+
Sbjct: 1927 RGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLIKG-EV 1985
Query: 1695 VNPDGFDVLRRVYVDFEGINFKRKFLTGLEPDAINVLIGSIRIDSLGTLSDLSDCEGRLF 1754
V +GF+V RRV+VDFEGI+ +RKFL GLEP+ I+++IGS+ ID LG L+DLSDCE +LF
Sbjct: 1986 VPENGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMMIGSMTIDCLGILNDLSDCEDKLF 2045
Query: 1755 PIGYQCSRLYWSTVDARRRCWYRCRILEYRPWGPREEPAHLEAAE--ENQTIVHSPAPSS 1812
PIGYQCSR+YWST DAR+RC Y C+I+E RP P EP E EN+TI HSP +
Sbjct: 2046 PIGYQCSRVYWSTTDARKRCVYTCKIVECRP--PVVEPDINSTVEHDENRTIAHSPTSFT 2103
Query: 1813 EPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSP 1872
E E +++ P +P+R PP SGS RI+ P+YSP
Sbjct: 2104 ESSSKESQN-TAEIISPPSPDR--------PPHSQTSGSCYYHVISKV--PRIRTPSYSP 2152
Query: 1873 SRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPR----RSRRPSPLAPRPPPSRW 1928
++R G PLPS GSP+ TH I TVGDP + R R S L+P+ R
Sbjct: 2153 TQRSPG---CRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLRI 2209
Query: 1929 ASPPLKTSPQLRVPPPTSVVTALTPTSGE---------LAPPGPAPSPPPPEDLGPDFED 1979
S P++T +SV T T T E L P + S + +
Sbjct: 2210 MS-PMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSSNLQR 2268
Query: 1980 MEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPV 2039
V G + LD ++S ++ A+ + S G+ ++ SS +S V
Sbjct: 2269 TVVTVGNKNSHLDGSSS-----SEMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNV 2323
Query: 2040 TVVSAPGLAP 2049
P LAP
Sbjct: 2324 AYPGIPKLAP 2333
Score = 487 bits (1254), Expect = e-137
Identities = 267/501 (53%), Positives = 334/501 (66%), Gaps = 36/501 (7%)
Query: 2215 VKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQ 2274
V+ P P SP++P+S P V G +P P L L +G +
Sbjct: 3505 VQASPTSPGGSPSSPSSGQRSASP-----SVPGPTKPKPKTKRFQLPLDKGNGK----KH 3555
Query: 2275 AIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGV 2334
+ R S+ P E T G G+ G + T +V
Sbjct: 3556 KVSHLRTSSSEAHIPD----------------QETTSLTSGTGTPGAEAEQQDTASVEQS 3599
Query: 2335 LDLDRPGEPAGEESPGPLQERSPLLPLPEDGPPQVPDGPPDLLLESQWHHYSGEASSSEE 2394
+ G+PAG+ + P + + ++ + P + E + + S ++
Sbjct: 3600 SQKEC-GQPAGQVAV------LPEVQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQ 3652
Query: 2395 EPPSPDDKENQAPKRTGPHLRFEISSEDGFSVEAESLEGAWRTLIEKVQEARGHARLRHL 2454
E + + PK+ L FEISS+DGF + AES+E AW++L +KVQEAR +ARL+ L
Sbjct: 3653 EQKRKESITEKKPKKG---LVFEISSDDGFQICAESIEDAWKSLTDKVQEARSNARLKQL 3709
Query: 2455 SFSGMSGARLLGIHHDAVIFLAEQLPGAQRCQHYKFRYHQQGEGQEEPPLNPHGAARAEV 2514
SF+G++G R+LGI HDAV+FL EQL GA+ C++YKFR+H+ E E PPLNPHG+ARAEV
Sbjct: 3710 SFAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANE-PPLNPHGSARAEV 3768
Query: 2515 YLRKCTFDMFNFLASQHRVLPEGATCDEEEDEVQLRSTRRATSLELPMAMRFRHLKKTSK 2574
+LRK FDMFNFLAS+HR PE DEEE+EVQL+S RRATS++LPM MRFRHLKKTSK
Sbjct: 3769 HLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLPMPMRFRHLKKTSK 3828
Query: 2575 EAVGVYRSAIHGRGLFCKRNIDAGEMVIEYSGIVIRSVLTDKREKFYDGKGIGCYMFRMD 2634
EAVGVYRS IHGRGLFCKRNIDAGEMVIEY+G VIRS+ TDKREK+YD KGIGCYMFR+D
Sbjct: 3829 EAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRID 3888
Query: 2635 DFDVVDATMHGNAARFINHSCEPNCFSRVIHVEGQKHIVIFALRRILRGEELTYDYKFPI 2694
D +VVDATMHGNAARFINHSCEPNC+SRVI+++GQKHIVIFA+R+I RGEELTYDYKFPI
Sbjct: 3889 DSEVVDATMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPI 3948
Query: 2695 EDASNKLPCNCGAKRCRRFLN 2715
EDASNKLPCNCGAK+CR+FLN
Sbjct: 3949 EDASNKLPCNCGAKKCRKFLN 3969
Score = 88.2 bits (217), Expect = 1e-16
Identities = 196/874 (22%), Positives = 301/874 (34%), Gaps = 244/874 (27%)
Query: 15 SARGRFPGRPRGAGGGGGRGGRG-NGAERVRVALRR-------GGGATG----------- 55
S R RFP RP GGGGG G RG GA R RV GGG G
Sbjct: 4 SCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAA 63
Query: 56 -----------PGGAE------------------------------PGEDTALLRLLGLR 74
PGGA PG D AL +
Sbjct: 64 AAAAGSSGAGVPGGAAAASAASSSSASSSSSSSSSASSGPALLRVGPGFDAALQVSAAIG 123
Query: 75 RGLRRLRRLWAGPRVQRGRGRGRGRGWGPSRGCVPEEESSDGESDEEEFQGFHSDEDVAP 134
LRR R ++ + G G G G ++E+F GF SDE+V
Sbjct: 124 TNLRRFRAVFG----ESGGGGGSG--------------------EDEQFLGFGSDEEV-- 157
Query: 135 SSLRSALRSQRGRAPRGRGRKHKTTPLPPPRLADVAPTPPKTPARKRGEEGTERMVQALT 194
R R+P R KT+P P R R G++R L+
Sbjct: 158 ----------RVRSPT-RSPSVKTSPRKP---------------RGRPRSGSDRNSAILS 191
Query: 195 E-----LLRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIPK 249
+ L +++ + + + + + RGRPP P + + + +PK
Sbjct: 192 DPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIK-----ITHGKDISELPK 246
Query: 250 PEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGGL-PFVIKFV 308
+ +K TP Q + + + R G L P KF
Sbjct: 247 GNKEDSLKKIKR----------------TPSATFQQATKIK----KLRAGKLSPLKSKF- 285
Query: 309 SRAKKVKMGQLSLGLESGQGQGQHEE-----------SWQDVPQRRVGSGQGGSPCWKKQ 357
+ K+++G+ + + +G+ E S + PQ+ +G P K
Sbjct: 286 -KTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTK-- 342
Query: 358 EQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAA--------EKEEAKLPPPPLTPP 409
E K + ++ + + ++ + +A++++ A EKE A+L +
Sbjct: 343 EDKTVVRQSPRRIKPVRIIPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQ 402
Query: 410 APSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKR 469
+ + P ++ + P + PP A+ E + P+ S ++
Sbjct: 403 VKNIRQFIMPVVSAISSRIIKTPRRFIEDEDY-DPPIKIARLESTPNSRFSAPSCGSSEK 461
Query: 470 GRPPLTPSQRAEREAARAGPEGTSPPTPT---------PSTATGGPPEDSPTVAPKSTTF 520
S + +++R+ T + P + P P +S
Sbjct: 462 SSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPEN 521
Query: 521 LKNIRQFIMPVVSARS--SRVIK-------TPRRFMDEDPPKPPKVEVSPVLRPPITTSP 571
N R+ VS RS SR K P++ PP PP + P L+P + S
Sbjct: 522 ESNDRRSRRYSVSERSFGSRTTKKLSTLQSAPQQQTSSSPP-PPLLTPPPPLQPASSISD 580
Query: 572 PVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSL--TRELP---------- 619
P P P +P P++ P+ KR+SILREPTFRWTSL +R P
Sbjct: 581 HTPWLMPPT-IPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQYFSSAKYAK 639
Query: 620 -------------PPPPAPPPPPAPSPPPAPATSS-----------------RRPLLLRA 649
PPP P S A T++ +R LLRA
Sbjct: 640 EGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRA 699
Query: 650 PQFTPSEAHLKIYESVLTP-----PPLGAPEAPEPEPPPADDSPAEPEPRAVG-----RT 699
P+FTPSEAH +I+ESV P + + SP EPR+ R+
Sbjct: 700 PRFTPSEAHSRIFESVTLPSNRTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRS 759
Query: 700 NHLSLPRFAPV-----VTTPVKAEVSPHGAPALS 728
LS +P+ V++ + VSP AL+
Sbjct: 760 GRLSSSELSPLTPPSSVSSSLSISVSPLATSALN 793
Score = 37.0 bits (84), Expect = 0.27
Identities = 63/291 (21%), Positives = 107/291 (36%), Gaps = 58/291 (19%)
Query: 1823 DTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRS----FSGARIKVPNYSPSRRPLG 1878
D + +PG P+ PP++ + + APR + +K+ N S S+ L
Sbjct: 2489 DKGLSMPGVPKA--------PPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALK 2540
Query: 1879 GVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQ 1938
SP SP + PT P + P+A +P P+ + +++
Sbjct: 2541 E------SSPASPLQIESTSPTE-----PISASENPGDGPVA-QPSPNNTSCQDSQSNNY 2588
Query: 1939 LRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAAS-L 1997
+P + P P P++ G S + +++ F + L
Sbjct: 2589 QNLPVQDRNLML--------------PDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPL 2634
Query: 1998 LGTEPFQEEIVA--AGAMGSSHG-----GPGDSSEEESSPTSR---YIHFPVTVVSAPGL 2047
G + EE + + + G G G D +++ S+ Y +F TV+S+ G
Sbjct: 2635 YGVRSYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGE 2694
Query: 2048 APSATPGA---------PRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPG 2089
A+ P+I QLDGVDDGT+S+ R P G
Sbjct: 2695 ERLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNG 2745
Score = 35.4 bits (80), Expect = 0.77
Identities = 39/179 (21%), Positives = 71/179 (39%), Gaps = 32/179 (17%)
Query: 101 WGPSRGCVPEEESSDGESDEEEFQGFHSDEDVAPSSLRSALRSQRGRAPRGRGRKHKTTP 160
W PS+ + ++++ + E++ + + S +++ + S + P R
Sbjct: 1199 WMPSKAYL-QKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSARED------ 1251
Query: 161 LPPPRLADVAPTPPKTPARKRGEEGT-----ERMVQALTELLRRAQA----------PQA 205
P P+ + P PP+ P ++ EEG QA T R++ PQ
Sbjct: 1252 -PAPKKSSSEP-PPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQP 1309
Query: 206 PRSRACEPSTPRRS-----RGRPPGRPAGPCRRKQQAVVVAEAAVTIPKP---EPPPPV 256
P + P+ + + +PP +GP + KQ+ V + KP E PPPV
Sbjct: 1310 PTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPRPSIPVKQKPKEKEKPPPV 1368
Score = 32.0 bits (71), Expect = 8.5
Identities = 53/247 (21%), Positives = 92/247 (37%), Gaps = 24/247 (9%)
Query: 2020 PGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAP--RIEQLDGVDDGTDSEAEAVQQ 2077
P DSS S P+ + S + + +P P +L + D + +
Sbjct: 2906 PVDSSVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITE- 2964
Query: 2078 PRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEI-VDFVLKNLGGPGDGGAGPREESL 2136
+ + S P ++ GV P + + D + G + G G ++
Sbjct: 2965 -KSVASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLT 3023
Query: 2137 PPAPPLANGSQPSQGLTASPADPTRTFAWLPGA---PGVRVLSLGPAPEPP---KPATSK 2190
N S P + SP P + ++P + PG +S P KPAT K
Sbjct: 3024 ------RNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEK 3077
Query: 2191 IILVNKLGQVFVKMAGEGEPVPPPVKQP-PLPPTIS--PTAPTSWTLPPGPLLGVLPVVG 2247
+I+VN+ Q + + +P V Q L ++S P+ + T GP+ G L +
Sbjct: 3078 LIVVNQNMQPLYVL----QTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTT 3133
Query: 2248 VVRPAPP 2254
+ P+ P
Sbjct: 3134 GLNPSLP 3140
>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
sapiens]
Length = 4911
Score = 188 bits (478), Expect = 5e-47
Identities = 109/294 (37%), Positives = 160/294 (54%), Gaps = 19/294 (6%)
Query: 2430 SLEGAWRTLIEKVQEARGHARLRHLSFSGMSGARLLGIHHDAVIFLAEQLPGAQRCQHYK 2489
S +G W ++E V R + + L + + G L G+ AV +AE LPG + C++Y
Sbjct: 4629 SPKGVWDKILEPVACVRKKSEMLQLFPAYLKGEDLFGLTVSAVARIAESLPGVEACENYT 4688
Query: 2490 FRYHQQGEGQEEPPLNPHGAARAEVYLRKCTFDMFNFLASQHRVLPEGATCDEEEDEVQL 2549
FRY + + +NP G AR+E K + + F+ H T +
Sbjct: 4689 FRYGRNPLMELPLAVNPTGCARSEP---KMSAHVKRFVLRPH-------TLNSTSTSKSF 4738
Query: 2550 RSTRRATSLELPMAMRFRHLKKTS--------KEAVGVYRSAIHGRGLFCKRNIDAGEMV 2601
+ST L P + +F H K + K V + RS I G GL+ R+I+ MV
Sbjct: 4739 QSTVTG-ELNAPYSKQFVHSKSSQYRKMKTEWKSNVYLARSRIQGLGLYAARDIEKHTMV 4797
Query: 2602 IEYSGIVIRSVLTDKREKFYDGKGIGCYMFRMDDFDVVDATMHGNAARFINHSCEPNCFS 2661
IEY G +IR+ + +++EK Y+ + G YMFRMD+ V+DAT+ G AR+INHSC PNC +
Sbjct: 4798 IEYIGTIIRNEVANRKEKLYESQNRGVYMFRMDNDHVIDATLTGGPARYINHSCAPNCVA 4857
Query: 2662 RVIHVEGQKHIVIFALRRILRGEELTYDYKFPIEDASNKLPCNCGAKRCRRFLN 2715
V+ E I+I + RRI +GEEL YDYKF ED +K+PC+CGA CR+++N
Sbjct: 4858 EVVTFERGHKIIISSSRRIQKGEELCYDYKFDFEDDQHKIPCHCGAVNCRKWMN 4911
Score = 139 bits (349), Expect = 5e-32
Identities = 81/211 (38%), Positives = 107/211 (50%), Gaps = 7/211 (3%)
Query: 1576 EDPRQCALCLKYGDADSKEAGRLLYIGQNEWTHVNCAIWSAEVFEENDGSLKNVHAAVAR 1635
+D R+C C + GD + RLL + + W H+NCA+WS EV+E G+L NV A+ R
Sbjct: 4397 KDYRKCCFCHEEGDGLTDGPARLLNLDLDLWVHLNCALWSTEVYETQAGALINVELALRR 4456
Query: 1636 GRQMRCELCLKPGATVGCCLSSCLSNFHFMCARASYCIFQDDKKVFCQKHTDLLDGKEIV 1695
G QM+C C K GAT GC C + +HF CA + C+F DK + C H G
Sbjct: 4457 GLQMKCVFCHKTGATSGCHRFRCTNIYHFTCAIKAQCMFFKDKTMLCPMHKP--KGIHEQ 4514
Query: 1696 NPDGFDVLRRVYVDFEGINFKRKFLTGLEPDAINVLIGSIRIDSLGTL----SDLSDCEG 1751
F V RRVYV + + + E D +GS+ ++G L
Sbjct: 4515 ELSYFAVFRRVYVQRDEVRQIASIVQRGERDH-TFRVGSLIFHTIGQLLPQQMQAFHSPK 4573
Query: 1752 RLFPIGYQCSRLYWSTVDARRRCWYRCRILE 1782
LFP+GY+ SRLYWST A RRC Y C I E
Sbjct: 4574 ALFPVGYEASRLYWSTRYANRRCRYLCSIEE 4604
Score = 107 bits (267), Expect = 2e-22
Identities = 59/176 (33%), Positives = 82/176 (46%), Gaps = 16/176 (9%)
Query: 1203 VCLLCASKGLH---ELVFCQVCCDPFHPFCLEEAERPLPQHHDTWCCRRCKFCHVCGRKG 1259
+C++C S G L+ C C +HP+C+ + W C C C CG K
Sbjct: 959 MCVVCGSFGQGAEGRLLACSQCGQCYHPYCVSIKITKVVLSKG-WRCLECTVCEACG-KA 1016
Query: 1260 RGSKHLLECERCRHAYHPACLGPSYPTRATRKRRHWICSACVRCKSCGATPGKNWDVEWS 1319
LL C+ C +YH CL P T + W C CV C+ CGAT EW
Sbjct: 1017 TDPGRLLLCDDCDISYHTYCLDPPLQTVP---KGGWKCKWCVWCRHCGATSA-GLRCEWQ 1072
Query: 1320 GDYSLCPRCTQLYEKGNYCPICTRCYEDNDYESKMMQCAQCDHWVHAKCEGLSDED 1375
+Y+ C C L + CP+C R Y + D ++QC QCD W+HA C+ L+ E+
Sbjct: 1073 NNYTQCAPCASL----SSCPVCYRNYREEDL---ILQCRQCDRWMHAVCQNLNTEE 1121
Score = 105 bits (261), Expect = 8e-22
Identities = 58/178 (32%), Positives = 80/178 (44%), Gaps = 20/178 (11%)
Query: 1204 CLLCASKG-LHELVFCQVCCDPFHPFCLEEAERPLPQHHDTWCCRRCKFCHVCGRKGRGS 1262
C +C S G L + FC C +H CL+ A PL + W C CK C C + G S
Sbjct: 344 CAVCDSPGDLLDQFFCTTCGQHYHGMCLDIAVTPLKRAG--WQCPECKVCQNCKQSGEDS 401
Query: 1263 KHLLECERCRHAYHPACLGP---SYPTRATRKRRHWICSACVRCKSCGATPGKNWDVEWS 1319
K +L C+ C YH CL P S PT W C C C CG +W
Sbjct: 402 K-MLVCDTCDKGYHTFCLQPVMKSVPTNG------WKCKNCRICIECGTRSSS----QWH 450
Query: 1320 GDYSLCPRCTQLYEKGNYCPICTRCYEDNDYESKMMQCAQCDHWVHAKCEGLSDEDYE 1377
+ +C C Q ++ N CP C +CY + + M+ C C WVH +C+ +D + +
Sbjct: 451 HNCLICDNCYQ--QQDNLCPFCGKCYHP-ELQKDMLHCNMCKRWVHLECDKPTDHELD 505
Score = 73.2 bits (178), Expect = 3e-12
Identities = 119/501 (23%), Positives = 181/501 (36%), Gaps = 76/501 (15%)
Query: 327 QGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQKLDDEEEEKKEEEEKD--------KEG 378
Q + +HE+ W+ Q R S Q + QKL+ + E+++++++ + G
Sbjct: 1742 QRESEHEQEWKFRQQMRQKSKQQAKI---EATQKLEQVKNEQQQQQQQQFGSQHLLVQSG 1798
Query: 379 EEKEERAVAEEMMPAAEK----------EEAKLPPPPLTPPA---------PSPPPPLPP 419
+ + + P +E PP TP + P PPP P
Sbjct: 1799 SDTPSSGIQSPLTPQPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVFVKPQAPPPPPA 1858
Query: 420 PSTSP------PPPLCPPPPPPVSPPPL-----PSPPPPPAQEEQEESPPPVVPATCSRK 468
PS P PP P V P PSP P A+ PPPV + R
Sbjct: 1859 PSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVGHSFSRRN 1918
Query: 469 RGRP-----PLT----PSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTT 519
P PL+ P Q E A R P + T + P D+P +
Sbjct: 1919 SAAPVENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNNDPYAKPPDTPRPV-MTDQ 1977
Query: 520 FLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAP 579
F K++ PVVS ++++ D P+ +V R P + + P+ PAP
Sbjct: 1978 FPKSLGLSRSPVVSEQTAKG-PIAAGTSDHFTKPSPRADVFQRQRIPDSYARPL-LTPAP 2035
Query: 580 VPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPAT 639
+ S P P P P + + + + R + E P P P + + P +
Sbjct: 2036 LDSGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYS 2095
Query: 640 SSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEP--EPP----PADDSPAEPEP 693
+P L P S AH + P + P + +P +PP P DS ++
Sbjct: 2096 ---QPPLTPHPAVNESFAHPS--RAFSQPGTISRPTSQDPYSQPPGTPRPVVDSYSQSSG 2150
Query: 694 RAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQAL 753
A T+ S P P TT V P+ + P TQ L Q P A
Sbjct: 2151 TARSNTDPYSQPPGTPRPTT-----VDPYSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAH 2205
Query: 754 PP--PQPQL-----QPPPSPQ 767
PP P+P + QPP +P+
Sbjct: 2206 PPGTPRPGISVPYSQPPATPR 2226
Score = 61.6 bits (148), Expect = 1e-08
Identities = 32/84 (38%), Positives = 39/84 (46%), Gaps = 3/84 (3%)
Query: 1606 WTHVNCAIWSAEVFEENDGSLKNVHAAVARGRQMRCELCLKPGATVGCCLSSCLSNFHFM 1665
W H C WS V + + L NV AV G RC C GAT+ CC C +H+
Sbjct: 250 WAHHRCVEWSLGVCQMEEPLLVNVDKAVVSGSTERCAFCKHLGATIKCCEEKCTQMYHYP 309
Query: 1666 CARASYCIFQDDKKVF--CQKHTD 1687
CA A FQD +F C +H D
Sbjct: 310 CA-AGAGTFQDFSHIFLLCPEHID 332
Score = 52.0 bits (123), Expect = 8e-06
Identities = 124/580 (21%), Positives = 186/580 (32%), Gaps = 113/580 (19%)
Query: 427 PLCPPPPPPVSPPPLPSP-PPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAA 485
PL P P P P +P PPP+ ++ S RP LTP
Sbjct: 2029 PLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHN 2088
Query: 486 RAGPEGTSPP-TPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPR 544
++ + PP TP P+ + +F R F P +R +
Sbjct: 2089 QSNDPYSQPPLTPHPAV---------------NESFAHPSRAFSQPGTISRPT------- 2126
Query: 545 RFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTP---------PSTPVP 595
+DP P PV+ +S P PP P P P TP P
Sbjct: 2127 ---SQDPYSQPPGTPRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRP 2183
Query: 596 LPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPS 655
+ + T +T + P A PP +P P + +P P+ +
Sbjct: 2184 STQTDLFV--------TPVTNQRHSDPYAHPPG---TPRPGISVPYSQPPATPRPRISEG 2232
Query: 656 EAHLKIYESVLTP---PPLGA-----PEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRF 707
+ VL P P L A P P P P D P P G ++ S
Sbjct: 2233 FTRSSMTRPVLMPNQDPFLQAAQNRGPALPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSP 2292
Query: 708 APVVTTPVKAEVSPHGAPALSNGPQTQAQLL-QPLQALQTQLLPQALPPPQPQLQPPPSP 766
+ ++ ++P QT + QP + + P Q Q
Sbjct: 2293 SAARDPYDQSPMTPRSQSDSFGTSQTAHDVADQPRPGSEGSFCASSNSPMHSQGQQFSGV 2352
Query: 767 QQMPPLEKARIAGVGSLPLSGVEEKMFS----------LLKRAKVQLFKIDQQQQQKVAA 816
Q+P G +P SGV + + L +R K++ + QQQQ+K+A
Sbjct: 2353 SQLP----------GPVPTSGVTDTQNTVNMAQADTEKLRQRQKLREIILQQQQQKKIA- 2401
Query: 817 SMPLSPGGQMEEVAGAVKQISDRGPVRS-EDESVEAKRERP--------SGPESPVQGPR 867
G+ E+ + + GP++ + E+V RP P +P GPR
Sbjct: 2402 -------GRQEKGSQDSPAVPHPGPLQHWQPENVNQAFTRPPPPYPGNIRSPVAPPLGPR 2454
Query: 868 IKHVCRHAAVALGQARAMVPEDVPRLSALPLRDRQDL--ATEDTSSASETESVPSRSRRG 925
AV R P DV + P R + T + E VP + +G
Sbjct: 2455 Y-------AVFPKDQRGPYPPDVASMGMRPHGFRFGFPGGSHGTMPSQERFLVPPQQIQG 2507
Query: 926 -----------KVEAAGPGGESEPTGSGGTLAHTPRRSLP 954
V+ P S+ G H +SLP
Sbjct: 2508 SGVSPQLRRSVSVDMPRPLNNSQMNNPVGLPQHFSPQSLP 2547
Score = 47.8 bits (112), Expect = 2e-04
Identities = 36/159 (22%), Positives = 59/159 (37%), Gaps = 43/159 (27%)
Query: 1203 VCLLCASKGLH-ELVFCQVCCDPFHPFCLEEAERPLPQHHDTWCCRRCKFCHVCGRKGRG 1261
VC C G +++ C C +H FCL+ + +P + W C+ C+ C CG +
Sbjct: 390 VCQNCKQSGEDSKMLVCDTCDKGYHTFCLQPVMKSVPTNG--WKCKNCRICIECGTRSSS 447
Query: 1262 SKH-------------------------------LLECERCRHAYHPACLGPSYPTRATR 1290
H +L C C+ H C P+ T+
Sbjct: 448 QWHHNCLICDNCYQQQDNLCPFCGKCYHPELQKDMLHCNMCKRWVHLECDKPTDHELDTQ 507
Query: 1291 KRRHWICSACVRCKSCGA-----TPGKNWDV-EWSGDYS 1323
+ +I C+ CK GA PG+ ++ E + DY+
Sbjct: 508 LKEEYI---CMYCKHLGAEMDRLQPGEEVEIAELTTDYN 543
Score = 39.7 bits (91), Expect = 0.041
Identities = 41/170 (24%), Positives = 64/170 (37%), Gaps = 23/170 (13%)
Query: 355 KKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEK-EEAKLPPPPLTPPAPSP 413
KK ++ +E+ E+ + + + +K+ + ++ AE E+ ++ AP
Sbjct: 3220 KKAGREFPEEDAEQLKHVTEQQSMVQKQLEQIRKQQKEHAELIEDYRIKQQQQCAMAP-- 3277
Query: 414 PPPLPPPSTSPPPPLCP-PPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRP 472
P PS P PPL P PP +S P P P Q+ Q + V+ S R
Sbjct: 3278 --PTMMPSVQPQPPLIPGATPPTMSQPTFPMVP----QQLQHQQHTTVISGHTSPV--RM 3329
Query: 473 PLTPSQRAEREAAR--AGPEGTSPP---------TPTPSTATGGPPEDSP 511
P P + A P PP TP P T + P+ P
Sbjct: 3330 PSLPGWQPNSAPAHLPLNPPRIQPPIAQLPIKTCTPAPGTVSNANPQSGP 3379
Score = 35.8 bits (81), Expect = 0.59
Identities = 25/71 (35%), Positives = 34/71 (47%), Gaps = 3/71 (4%)
Query: 349 GGSPCWKKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAE-KEEAKLPPPPLT 407
GGS KKQ K EK K ++ +E+E++A+ K++ L PP T
Sbjct: 3842 GGSET-KKQRSKRTQRTGEKAAPRSKKRKKDEEEKQAMYSSTDTFTHLKQQNNLSNPP-T 3899
Query: 408 PPAPSPPPPLP 418
PPA PP P P
Sbjct: 3900 PPASLPPTPPP 3910
Score = 35.4 bits (80), Expect = 0.77
Identities = 20/50 (40%), Positives = 25/50 (50%), Gaps = 5/50 (10%)
Query: 442 PSPPPPPAQEEQEESPPPVVPATCSRKRGRP---PLTPSQRAEREAARAG 488
P PPPPP +E +P P A R RGRP +P QRA ++ G
Sbjct: 12 PQPPPPPPEEPGAPAPSPA--AADKRPRGRPRKDGASPFQRARKKPRSRG 59
Score = 34.3 bits (77), Expect = 1.7
Identities = 14/28 (50%), Positives = 18/28 (64%), Gaps = 1/28 (3%)
Query: 617 ELPPPPPAPPPPPAPSPPPAPATSSRRP 644
E P PPP PP P +P P+PA + +RP
Sbjct: 10 EQPQPPPPPPEEPG-APAPSPAAADKRP 36
Score = 33.9 bits (76), Expect = 2.2
Identities = 20/66 (30%), Positives = 25/66 (37%)
Query: 431 PPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPE 490
PPPPP P P+P P A + P + R R +P E E + G E
Sbjct: 14 PPPPPPEEPGAPAPSPAAADKRPRGRPRKDGASPFQRARKKPRSRGKTAVEDEDSMDGLE 73
Query: 491 GTSPPT 496
T T
Sbjct: 74 TTETET 79
Score = 32.7 bits (73), Expect = 5.0
Identities = 14/26 (53%), Positives = 14/26 (53%)
Query: 619 PPPPPAPPPPPAPSPPPAPATSSRRP 644
PPPPP P PAPSP A RP
Sbjct: 15 PPPPPEEPGAPAPSPAAADKRPRGRP 40
Score = 32.7 bits (73), Expect = 5.0
Identities = 36/114 (31%), Positives = 45/114 (39%), Gaps = 23/114 (20%)
Query: 215 TPRRSRGRP--------PGRPAGPCRRKQQAVVVAEAAVTIPKPEPP----PPVVPVKHQ 262
TP+ G+P PGRP R +Q V+ P P + +
Sbjct: 820 TPKIGMGKPAITKRKFSPGRP-----RSKQGAWSTHNTVSPPSWSPDISEGREIFKPRQL 874
Query: 263 TGS--WKCKEGPG---PGPGTPRRGGQSSRGGRGGRGRGRGGGLPFVIKFVSRA 311
GS W K G G PG PR G S RGGR GR + + G V+ VS A
Sbjct: 875 PGSAIWSIKVGRGSGFPGKRRPRGAGLSGRGGR-GRSKLKSGIGAVVLPGVSTA 927
Score = 32.3 bits (72), Expect = 6.5
Identities = 32/114 (28%), Positives = 39/114 (34%), Gaps = 9/114 (7%)
Query: 412 SPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPAT-CSRKRG 470
S PP P P+T P P P P + L P + + PP P S
Sbjct: 2160 SQPPGTPRPTTVDPYSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYS 2219
Query: 471 RPPLTPSQRAEREAARAGPEGTSP---PTPTP---STATGGPPEDSPTVAPKST 518
+PP TP R R+ T P P P + GP P V P T
Sbjct: 2220 QPPATPRPRISEGFTRSSM--TRPVLMPNQDPFLQAAQNRGPALPGPLVRPPDT 2271
Score = 32.3 bits (72), Expect = 6.5
Identities = 20/55 (36%), Positives = 24/55 (43%), Gaps = 3/55 (5%)
Query: 405 PLTPPAPSP--PPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESP 457
P + PA P PP + PP P C P P VS P PPP E + +P
Sbjct: 3337 PNSAPAHLPLNPPRIQPPIAQLPIKTCTPAPGTVSNAN-PQSGPPPRVEFDDNNP 3390
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 185 bits (470), Expect = 5e-46
Identities = 103/291 (35%), Positives = 158/291 (54%), Gaps = 17/291 (5%)
Query: 2430 SLEGAWRTLIEKVQEARGHARLRHLSFSGMSGARLLGIHHDAVIFLAEQLPGAQRCQHYK 2489
S + W +IE V R A + L + G L G+ AV+ +AE LPG + CQ+Y
Sbjct: 5259 SPQAVWNRIIEPVAAMRKEADMLRLFPEYLKGEELFGLTVHAVLRIAESLPGVESCQNYL 5318
Query: 2490 FRYHQQGEGQEEPPLNPHGAARAEV-----YLRKCTFDMFNFLASQHRVLPEGATCDEEE 2544
FRY + + +NP G AR+E Y R T + + + +
Sbjct: 5319 FRYGRHPLMELPLMINPTGCARSEPKILTHYKRPHTLNSTSMSKAYQSTFTGETNTPYSK 5378
Query: 2545 DEVQLRSTRRATSLELPMAMRFRHLKKTSKEAVGVYRSAIHGRGLFCKRNIDAGEMVIEY 2604
V +S++ +R L+ K V + RS I G GL+ ++++ MVIEY
Sbjct: 5379 QFVHSKSSQ------------YRRLRTEWKNNVYLARSRIQGLGLYAAKDLEKHTMVIEY 5426
Query: 2605 SGIVIRSVLTDKREKFYDGKGIGCYMFRMDDFDVVDATMHGNAARFINHSCEPNCFSRVI 2664
G +IR+ + ++REK Y+ + G YMFR+++ V+DAT+ G AR+INHSC PNC + V+
Sbjct: 5427 IGTIIRNEVANRREKIYEEQNRGIYMFRINNEHVIDATLTGGPARYINHSCAPNCVAEVV 5486
Query: 2665 HVEGQKHIVIFALRRILRGEELTYDYKFPIEDASNKLPCNCGAKRCRRFLN 2715
+ + I+I + RRI +GEELTYDY+F ED +K+PC+CGA CR+++N
Sbjct: 5487 TFDKEDKIIIISSRRIPKGEELTYDYQFDFEDDQHKIPCHCGAWNCRKWMN 5537
Score = 129 bits (324), Expect = 4e-29
Identities = 71/211 (33%), Positives = 109/211 (51%), Gaps = 9/211 (4%)
Query: 1577 DPRQCALCLKYGDADSKEAGRLLYIGQNEWTHVNCAIWSAEVFEENDGSLKNVHAAVARG 1636
D R+C C + GD + RLL + + W H+NCA+WS EV+E G+L NV A+ RG
Sbjct: 5028 DMRRCCFCHEEGDGATDGPARLLNLDLDLWVHLNCALWSTEVYETQGGALMNVEVALHRG 5087
Query: 1637 RQMRCELCLKPGATVGCCLSSCLSNFHFMCARASYCIFQDDKKVFCQKHTDLLDGKEIVN 1696
+C LC + GAT C C + +HF CA + C+F DK + C H + G
Sbjct: 5088 LLTKCSLCQRTGATSSCNRMRCPNVYHFACAIRAKCMFFKDKTMLCPMHK--IKGPCEQE 5145
Query: 1697 PDGFDVLRRVYVDFEGINFKRKFLTGLEPDAINVL-IGSIRIDSLGTL--SDLSDCEG-- 1751
F V RRVY++ + + + + +++ +G + ++G L ++D
Sbjct: 5146 LSSFAVFRRVYIERDEVKQIASIIQ--RGERLHMFRVGGLVFHAIGQLLPHQMADFHSAT 5203
Query: 1752 RLFPIGYQCSRLYWSTVDARRRCWYRCRILE 1782
L+P+GY+ +R+YWS RRC YRC I E
Sbjct: 5204 ALYPVGYEATRIYWSLRTNNRRCCYRCSIGE 5234
Score = 125 bits (313), Expect = 7e-28
Identities = 137/457 (29%), Positives = 183/457 (40%), Gaps = 66/457 (14%)
Query: 371 EEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPL-PPPSTSP--PP- 426
EE E+ + E P + EE+ L PP +PP+P+ PL PPP SP PP
Sbjct: 490 EESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPF 549
Query: 427 ---PLCPPP------PPP----VSPPPLPSPPPPPAQEEQEESPPP----VVPATCSRKR 469
PL PPP PPP +SPPP SP PP EE SPPP + P
Sbjct: 550 EESPLSPPPEELPTSPPPEASRLSPPPEESPMSPP-PEESPMSPPPEASRLFPPFEESPL 608
Query: 470 GRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIM 529
PP EA+R P PP +P + PPE+SP P + L +
Sbjct: 609 SPPPEESPLSPPPEASRLSP----PPEDSPMSP---PPEESPMSPPPEVSRLSP-----L 656
Query: 530 PVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPR---- 585
PVVS S ++P E+ P P E S + PP + P E +P PP
Sbjct: 657 PVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLM 716
Query: 586 -APTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRP 644
P S +PLPE EP S L P P P P P P + + P
Sbjct: 717 SLPLEESPLLPLPE-------EPQLCPRSEGPHLSPRPEEPHLSPRPEEPHL-SPQAEEP 768
Query: 645 LLLRAPQ-----FTPSEAHL--KIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVG 697
L P+ P E HL + L+P P +P+ E P P EP
Sbjct: 769 HLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQP 828
Query: 698 RTNHLSLPRFAPVVT-TPVKAEVSPH-GAPALSNGPQTQAQLLQPLQALQTQLLPQALPP 755
+HLS P ++ P ++ +SP P LS P+ + +P Q + LP PP
Sbjct: 829 EESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPE--EPGQCPAPEELPLFPPP 886
Query: 756 PQPQLQPPPSPQQMPPLEKARIAGVGSLPLSGVEEKM 792
+P L P L + ++ G PLS + E++
Sbjct: 887 GEPSLS--------PLLGEPALSEPGEPPLSPLPEEL 915
Score = 120 bits (302), Expect = 1e-26
Identities = 122/392 (31%), Positives = 165/392 (42%), Gaps = 67/392 (17%)
Query: 405 PLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPAT 464
PL P L P P L PP P+SPPP SP PP + + PP +PA+
Sbjct: 418 PLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPAS 477
Query: 465 CSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNI 524
P R E+ + P SP +P P ++ P E+SP P+ +
Sbjct: 478 -----PLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESP----- 527
Query: 525 RQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPP--ITTSPPVPQEPAPVPS 582
S ++TP E P P E SP+ PP + TSPP P+ P
Sbjct: 528 -----------PSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPP-PEASRLSPP 575
Query: 583 P---PRAPTPPSTPV-PLPEKRRSILREPTFRWTSLT-----RELPPPPPA----PPPPP 629
P P +P P +P+ P PE R P F + L+ L PPP A PPP
Sbjct: 576 PEESPMSPPPEESPMSPPPEASRLF---PPFEESPLSPPPEESPLSPPPEASRLSPPPED 632
Query: 630 AP-SPPPAPATSSRRPLLLR-APQFTPSEAHLKIYESVLTPPPLGAPEAPEPE-----PP 682
+P SPPP + S P + R +P S ES L+PPP +P +P PE PP
Sbjct: 633 SPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPP 692
Query: 683 PAD--------DSPAEPEPRAVGRTNHLSLP-RFAPVVTTPVKAEVSPHG-APALSNGPQ 732
P D DSPA P P + +SLP +P++ P + ++ P P LS P+
Sbjct: 693 PEDSPTSPPPEDSPASPPP----EDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLS--PR 746
Query: 733 TQAQLLQPLQALQTQLLPQALPPPQPQLQPPP 764
+ L P + + L PQA +P L P P
Sbjct: 747 PEEPHLSP-RPEEPHLSPQA---EEPHLSPQP 774
Score = 104 bits (259), Expect = 1e-21
Identities = 68/210 (32%), Positives = 93/210 (44%), Gaps = 31/210 (14%)
Query: 1203 VCLLCASKGLH---ELVFCQVCCDPFHPFCLEEAERPLPQHHDTWCCRRCKFCHVCGRKG 1259
+C++C S G L+ C C +HP+C+ + W C C C VCG+
Sbjct: 1379 MCVVCGSFGRGAEGHLLACSQCSQCYHPYCVNSKITKVMLLKG-WRCVECIVCEVCGQAS 1437
Query: 1260 RGSKHLLECERCRHAYHPACLGPSYPTRATRKRRHWICSACVRCKSCGA-TPGKNWDVEW 1318
S+ LL C+ C +YH CL P T + W C CV C CGA +PG + EW
Sbjct: 1438 DPSRLLL-CDDCDISYHTYCLDPPL---LTVPKGGWKCKWCVSCMQCGAASPG--FHCEW 1491
Query: 1319 SGDYSLCPRCTQLYEKGNYCPICTRCYEDNDYESKMMQCAQCDHWVHAKCEGL------- 1371
Y+ C C L CPIC Y + D ++QC C+ W+HA CE L
Sbjct: 1492 QNSYTHCGPCASLVT----CPICHAPYVEEDL---LIQCRHCERWMHAGCESLFTEDDVE 1544
Query: 1372 --SDEDYEILSGLPDSVLYTCGPCAGAAQP 1399
+DE ++ +S P Y P A A P
Sbjct: 1545 QAADEGFDCVSCQP----YVVKPVAPVAPP 1570
Score = 83.6 bits (205), Expect = 2e-15
Identities = 51/149 (34%), Positives = 66/149 (44%), Gaps = 15/149 (10%)
Query: 1204 CLLCASKG-LHELVFCQVCCDPFHPFCLEEAERPLPQHHDTWCCRRCKFCHVCGRKGRGS 1262
C +C G L +L FC C +H CL+ A + W C CK C C + G S
Sbjct: 229 CAVCEGPGELCDLFFCTSCGHHYHGACLDTALTA--RKRAGWQCPECKVCQACRKPGNDS 286
Query: 1263 KHLLECERCRHAYHPACLGPSYPTRATRKRRHWICSACVRCKSCGATPGK-NWDVEWSGD 1321
K +L CE C YH CL P W C AC C++CGA + N + EW +
Sbjct: 287 K-MLVCETCDKGYHTFCLKPPMEELPAHS---WKCKACRVCRACGAGSAELNPNSEWFEN 342
Query: 1322 YSLCPRC-------TQLYEKGNYCPICTR 1343
YSLC RC T + P+C+R
Sbjct: 343 YSLCHRCHKAQGGQTIRSVAEQHTPVCSR 371
Score = 80.1 bits (196), Expect = 3e-14
Identities = 155/637 (24%), Positives = 214/637 (33%), Gaps = 112/637 (17%)
Query: 162 PPPRLADVAPTPPKTPARKRGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPRRSRG 221
PPP + ++P P +P EE ++ L +P SR P
Sbjct: 619 PPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRL-----SPLPVVSRLSPPPEESPLSP 673
Query: 222 RPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPG-PGPGTPR 280
P P P + E + T P PE P P + S +E P P P P+
Sbjct: 674 PPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQ 733
Query: 281 RGGQSSRGGRGGRGRGRGGGLPFVIKFVSRAKKVKMGQLSLGLESGQGQGQHEESWQ-DV 339
+S G L + + + + LS E Q EE V
Sbjct: 734 LCPRSE-----------GPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAV 782
Query: 340 PQRRVGSGQGGSPCWKKQEQKLDDEEEEKK-------EEEEKDKEGEEKEERAVAEEMMP 392
P+ S Q P Q ++L + ++ EE + EE +EE
Sbjct: 783 PEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCL 842
Query: 393 AAEKEEAKLPPPPLTPP-APSPPPPLPPPSTSPPP---PLCPPP-PPPVSP----PPLPS 443
+ EE+ L P PP +P P P P P P PL PPP P +SP P L
Sbjct: 843 SPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSE 902
Query: 444 PPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTAT 503
P PP EE P+ P+ G P L+P PP P
Sbjct: 903 PGEPPLSPLPEEL--PLSPS------GEPSLSPQ--------------LMPPDPL----- 935
Query: 504 GGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVL 563
PP SP + + L + + P + D DP P +P+L
Sbjct: 936 --PPPLSPIITAAAPPALSPLGELEYPFGAKG------------DSDPESP---LAAPIL 978
Query: 564 RPPITTSP------PVPQEPAPVPSPPRAPTPPSTPV---PLPEKRRSILREPTFRWTSL 614
PI+ P P P P +P P +P P++P+ PLP + +L+ S
Sbjct: 979 ETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNS- 1037
Query: 615 TRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPP-PLGA 673
PP PP P P+P + P+ +E H E V P P
Sbjct: 1038 ------PPSQCSPPALPLSVPSPLS----PIGKVVGVSDEAELHEMETEKVSEPECPALE 1087
Query: 674 PEAPEPEPPPADD-SPAEPEPRAVGRTNHLSLPRFAPV--VTTPVKAEVSPHGAPALSNG 730
P A P P P D S P P +L F+ + T P+ +P P
Sbjct: 1088 PSATSPLPSPMGDLSCPAPSPAP-------ALDDFSGLGEDTAPLDGIDAPGSQP---EP 1137
Query: 731 PQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQ 767
QT L L+ L P+ L P P P Q
Sbjct: 1138 GQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQ 1174
Score = 79.3 bits (194), Expect = 5e-14
Identities = 149/584 (25%), Positives = 196/584 (33%), Gaps = 103/584 (17%)
Query: 1810 PSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPN 1869
P E P E+ PL L P SP P P S P P + + P
Sbjct: 428 PQLEAPLNEEMPL----LPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPL--PE 481
Query: 1870 YSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSP-----LAPRPP 1924
RPL P P S P + P P PSP L+P PP
Sbjct: 482 ALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSP-PP 540
Query: 1925 PSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELA-PPGPAPSPPPPED--LGPDFEDME 1981
+ SPP + SP PPP + T+ P + L+ PP +P PPPE+ + P E
Sbjct: 541 EASPLSPPFEESPLS--PPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPE--- 595
Query: 1982 VVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTV 2041
AS L PF+E ++ S P ++S P + P
Sbjct: 596 -------------ASRL-FPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPP--- 638
Query: 2042 VSAPGLAP-SATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAG 2100
P +P S P R+ L V + E+ P + +P S P A
Sbjct: 639 ---PEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPP--------PEAS 687
Query: 2101 DRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPT 2160
+ PPED P+ + P E+S PA P S S L SP P
Sbjct: 688 RLSPPPEDSPT-----------------SPPPEDS--PASPPPEDSLMSLPLEESPLLP- 727
Query: 2161 RTFAWLPGAPGVRVLSLGP--APEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQP 2218
LP P + S GP +P P +P S L + +P P +
Sbjct: 728 -----LPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAV 782
Query: 2219 PLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQ---- 2274
P P +SP A P L + P +P P P L+ SP +
Sbjct: 783 PEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCL 842
Query: 2275 --AIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVR 2332
+S + P +P P K P A E+ P P G S +
Sbjct: 843 SPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLS-------PLL 895
Query: 2333 GVLDLDRPGEPAGEESPGPLQERSPLLPLPEDGPPQVPDGPPDL 2376
G L PGEP PL PLPE+ P P G P L
Sbjct: 896 GEPALSEPGEP-------------PLSPLPEE-LPLSPSGEPSL 925
Score = 76.6 bits (187), Expect = 3e-13
Identities = 120/417 (28%), Positives = 156/417 (37%), Gaps = 83/417 (19%)
Query: 2047 LAPSATPGAPRIEQLDGVDDGTDSEAEAVQ-----QPRG---QGTPPSGPGVVR--AGVL 2096
+A TP R + D TD E +A+ QP+G P PG ++ A L
Sbjct: 361 VAEQHTPVCSRFSPPEPGDTPTD-EPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPL 419
Query: 2097 GAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPP--LANGSQPSQGLTA 2154
G AG + P + P ++ + L P + P E P +PP + S P + L A
Sbjct: 420 GKAGVQLEPQLEAP---LNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPA 476
Query: 2155 SPADP----TRTFAWLPGAPGVRVLSLGPAPE--PPKPATSKIILVNKLGQVFVKMAGEG 2208
SP +R P +P L P PE P P E
Sbjct: 477 SPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPL-------------------EE 517
Query: 2209 EPVPPPVKQPPL---------PPTISPTAP---TSWTLPPGPLLGVLPVVGVVRPAPPPP 2256
P+ PP + PP PP SP +P S PP L P R +PPP
Sbjct: 518 SPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPE 577
Query: 2257 PPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEAS------EDT 2310
P++ P SPP +A R+ F SP +PPP ++P L EAS ED+
Sbjct: 578 ESPMSPPPEESPMSPPPEASRL--FPPFE-ESPLSPPPEESP-LSPPPEASRLSPPPEDS 633
Query: 2311 PQVPGLGSGGFSRVRMKTPTVRGVLDL-----------DRPGEPAGEESP-GPLQERSPL 2358
P P S P V + L + P P EESP P E S L
Sbjct: 634 PMSPPPEESPMS----PPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRL 689
Query: 2359 LPLPEDGPPQVPDGPPDLLLESQWHHYSGEASSSEEEPPSPDDKENQ-APKRTGPHL 2414
P PED P PP+ S S + EE P P +E Q P+ GPHL
Sbjct: 690 SPPPEDSP---TSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHL 743
Score = 72.0 bits (175), Expect = 7e-12
Identities = 134/528 (25%), Positives = 190/528 (35%), Gaps = 164/528 (31%)
Query: 1914 RRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELA-PPGPAPSPPPPE- 1971
+ P PL P A L+ PQL P + P L+ PP +P+ PPPE
Sbjct: 407 KEPGPLQCEAKPLGKAGVQLE--PQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEA 464
Query: 1972 -DLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSP 2030
L P E+ L A+ L A L + P +E ++ S P ESSP
Sbjct: 465 SRLSPPPEE------LPASPLPEALHL--SRPLEESPLSPPPEESPLSPP-----PESSP 511
Query: 2031 TSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGV 2090
S P++ P +P +P + E P + +P S P
Sbjct: 512 FSPLEESPLS-------PPEESPPSPAL--------------ETPLSPPPEASPLSPP-- 548
Query: 2091 VRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQ 2150
+ PPE+LP+ P P E P +PP P +
Sbjct: 549 ------FEESPLSPPPEELPTS---------PPPEASRLSPPPEESPMSPP------PEE 587
Query: 2151 GLTASPADPTRTFAWLPGAPGVRVLSLGPAPE----PPKPATSKIILVNKLGQVFVKMAG 2206
+ P + +R F +P L P PE P P S++
Sbjct: 588 SPMSPPPEASRLFPPFEESP------LSPPPEESPLSPPPEASRL-----------SPPP 630
Query: 2207 EGEPVPPPVKQPPL--PPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVL 2264
E P+ PP ++ P+ PP +S +P LPVV R +PPP PL+
Sbjct: 631 EDSPMSPPPEESPMSPPPEVSRLSP-------------LPVVS--RLSPPPEESPLSPPP 675
Query: 2265 SSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRV 2324
P SPP +A R+S SP +PPP ED+P P
Sbjct: 676 EESPTSPPPEA---SRLSPPPEDSPTSPPP-------------EDSPASP---------- 709
Query: 2325 RMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLPLPEDGPPQV---PDGP-------- 2373
P ++ L PL+E SPLLPLPE+ PQ+ +GP
Sbjct: 710 ----PPEDSLMSL-------------PLEE-SPLLPLPEE--PQLCPRSEGPHLSPRPEE 749
Query: 2374 PDLLLESQWHHYSGEA-----SSSEEEP--PSPDDKENQAPKRTGPHL 2414
P L + H S +A S EEP + ++ + +P+ GPHL
Sbjct: 750 PHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHL 797
Score = 70.9 bits (172), Expect = 2e-11
Identities = 113/415 (27%), Positives = 143/415 (34%), Gaps = 81/415 (19%)
Query: 402 PPPPLTPPAPSPPPPLPPPSTSPPPPLCPP-----------------PPPPVSPPPLPSP 444
P PL P P+ PP PP + P PP PP +P PS
Sbjct: 2181 PAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPST 2240
Query: 445 PPP---PAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAE-REAARAGPEGTSPPTPTPS 500
P P P + P P K P L+P E R+A E +P
Sbjct: 2241 PDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSP--- 2297
Query: 501 TATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVS 560
+ GPP +P S T L + +KTP F P+ +VE
Sbjct: 2298 --SYGPPNLGFVDSPSSGTHLGGLE--------------LKTPDVFKAPLTPRASQVE-- 2339
Query: 561 PVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPP 620
P PQEP P + AP+PPS P R +P + R PP
Sbjct: 2340 ----PQSPGLGLRPQEPPPAQA--LAPSPPSHPDIF---RPGSYTDPYAQPPLTPRPQPP 2390
Query: 621 PPP---APPPPPAPSPP-------PAPATSSRRPLL---LRAPQFTPSEAHLKIYESVLT 667
PP A PP PS P P +SS+ PL L A F PS +
Sbjct: 2391 PPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPY 2450
Query: 668 PPPLGAPEAPEPEPPPADDSPAEPEPRAV----GRTNHLSL-----PRFAPV-VTTPVKA 717
P P++ +P P P P+P V G H SL P P + A
Sbjct: 2451 SRPPSRPQSRDPFAPL--HKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHA 2508
Query: 718 EVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPP-PSPQQMPP 771
+V P P T A + P T PQA+ +P L+PP P P PP
Sbjct: 2509 KVPSGQPPNFVRSPGTGAFVGTPSPMRFT--FPQAV--GEPSLKPPVPQPGLPPP 2559
Score = 69.3 bits (168), Expect = 5e-11
Identities = 164/669 (24%), Positives = 216/669 (32%), Gaps = 132/669 (19%)
Query: 1782 EYRPWGPREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSP---I 1838
E P P E + L E + SP P P PP ++ + P R SP +
Sbjct: 604 EESPLSPPPEESPLSPPPEASRL--SPPPEDSPMS--PPPEESPMSPPPEVSRLSPLPVV 659
Query: 1839 QNLDPP-----LRP---DSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGS 1890
L PP L P +S ++PPP S P SP+ P P P
Sbjct: 660 SRLSPPPEESPLSPPPEESPTSPPPEASRLSPP----PEDSPTSPPPEDSPASPPPEDSL 715
Query: 1891 PSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKT--SPQLRVP----PP 1944
S P + P+ P RS P L+PRP + P + SPQ P P
Sbjct: 716 MSLPLEESPLLPLPEEPQLCPRSEGPH-LSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQP 774
Query: 1945 TSVVTALTPTSGELAPP--GPAPSPPPPE-DLGPDFEDMEVVSGLSAADLDFAASLLGTE 2001
P L+P GP SP P E L P E+ + L
Sbjct: 775 EEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLS 834
Query: 2002 PFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSAT-------PG 2054
P EE + SH P E E P S P PG P+ PG
Sbjct: 835 PQSEEPCLSPRPEESHLSP----ELEKPPLSPR---PEKPPEEPGQCPAPEELPLFPPPG 887
Query: 2055 APRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGD-----RARPPEDL 2109
P + L G A+ +P G PP P + L +G+ + PP+ L
Sbjct: 888 EPSLSPLLG--------EPALSEP---GEPPLSP-LPEELPLSPSGEPSLSPQLMPPDPL 935
Query: 2110 PSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGA 2169
P + ++ P G E P A G + A+P T P +
Sbjct: 936 PPPLSP-IITAAAPPALSPLGELEY-----PFGAKGDSDPESPLAAPILET------PIS 983
Query: 2170 PGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPP--PVKQPPLPPTISP- 2226
P P P PP + G PV P P+ PLPP SP
Sbjct: 984 PPPEANCTDPEPVPP----------------MILPPSPGSPVGPASPILMEPLPPQCSPL 1027
Query: 2227 --------TAPTSWTLPPG-------PLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASP 2271
+P S PP PL + VVGV A + PA
Sbjct: 1028 LQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALE 1087
Query: 2272 PRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTV 2331
P + S S PAP P AP LD+ EDT + G
Sbjct: 1088 PSATSPLP--SPMGDLSCPAPSP--APALDDFSGLGEDTAPLDG---------------- 1127
Query: 2332 RGVLDLDRPG-EPAGEESPGPLQERSPLLPLPEDGPPQVPDGPPDLLLESQWHHYSGEAS 2390
+D PG +P ++PG L P+ D P P ++ E + G
Sbjct: 1128 -----IDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPC 1182
Query: 2391 SSEEEPPSP 2399
+EEP +P
Sbjct: 1183 EEQEEPRAP 1191
Score = 62.8 bits (151), Expect = 5e-09
Identities = 101/423 (23%), Positives = 146/423 (34%), Gaps = 61/423 (14%)
Query: 1788 PREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQN---LDPP 1844
PR E +HL E + P E PG P + + P SP+ L P
Sbjct: 844 PRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEP 903
Query: 1845 LRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSP---SSLTHHIPTV 1901
P P P S SG P+ SP P PLP P SP ++ + +
Sbjct: 904 GEPPLSPLPEELPLSPSGE----PSLSPQLMPPD-----PLPPPLSPIITAAAPPALSPL 954
Query: 1902 GDPDFPAPPRRSRRP-SPLAP-------RPPPSRWASPPLKTSPQLRVPPPTSVVTALTP 1953
G+ ++P + P SPLA PPP + P P + P P S V +P
Sbjct: 955 GELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASP 1014
Query: 1954 TSGELAPP--------GPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQE 2005
E PP P PP P + V S LS +G
Sbjct: 1015 ILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSP---------IGKVVGVS 1065
Query: 2006 EIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVD 2065
+ M + + E S TS + P+ +S P +P AP ++ G+
Sbjct: 1066 DEAELHEMETEKVSEPECPALEPSATSP-LPSPMGDLSCPAPSP-----APALDDFSGLG 1119
Query: 2066 DGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDL----PSEIVDFVLKNL 2121
+ T + + + P Q P PG + + + G+ PE+L P E+ +
Sbjct: 1120 EDT-APLDGIDAPGSQPEPGQTPGSLASELKGS--PVLLDPEELAPVTPMEVYPECKQTA 1176
Query: 2122 --GGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGP 2179
G P + PR P P L ++ S D + +F PG L P
Sbjct: 1177 GQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASASF------PGSEPLLGSP 1230
Query: 2180 APE 2182
PE
Sbjct: 1231 DPE 1233
Score = 61.6 bits (148), Expect = 1e-08
Identities = 159/638 (24%), Positives = 207/638 (32%), Gaps = 107/638 (16%)
Query: 1782 EYRPWGPREEPAHLEAAEENQTIVHSP--APSSEPPGGED-PPLDTDVLVPGAPERHSPI 1838
E P P E HL E + P +P S PP PL+ L P PE P
Sbjct: 472 EELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSP--PEESPPS 529
Query: 1839 QNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLP--SPGSPSSLTH 1896
L+ PL P ++P P S P P+ P P P SP SP
Sbjct: 530 PALETPLSPPPEASPLSPPFEESPLS-PPPEELPTSPPPEASRLSPPPEESPMSP----- 583
Query: 1897 HIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSG 1956
P P P PP SR P P SPP + SP PPP + + P
Sbjct: 584 --PPEESPMSP-PPEASRLFPPFEESP-----LSPPPEESPLS--PPPEASRLSPPPEDS 633
Query: 1957 ELAPPGPAPSP--PPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMG 2014
++PP P SP PPPE VS LS + S L P + +
Sbjct: 634 PMSPP-PEESPMSPPPE-----------VSRLSPLPV---VSRLSPPPEESPL------- 671
Query: 2015 SSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEA 2074
S E SPTS P S P +P +P E DS
Sbjct: 672 --------SPPPEESPTS-----PPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSL 718
Query: 2075 VQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREE 2134
+ P P + R P P + P P E
Sbjct: 719 PLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEP-HLSPQPEEP 777
Query: 2135 SLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPP--KPATSKII 2192
L P + S ++G SP L +P L P PE P P +
Sbjct: 778 CLCAVPEEPHLSPQAEGPHLSPQPEE-----LHLSPQTEEPHLSPVPEEPCLSPQPEESH 832
Query: 2193 LVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPA 2252
L + + + E + P +++PPL P P P P P G P +
Sbjct: 833 LSPQSEEPCLSPRPEESHLSPELEKPPLSP--RPEKP-----PEEP--GQCPAPEELPLF 883
Query: 2253 PPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEAS----- 2307
PPP P L+ +L S P G P +P P + P L GE S
Sbjct: 884 PPPGEPSLSPLLGEPALSEP-------------GEPPLSPLPEELP-LSPSGEPSLSPQL 929
Query: 2308 -EDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESP-GPLQERSPLLPLPEDG 2365
P P L P + + +L+ P G+ P PL +P+L P
Sbjct: 930 MPPDPLPPPLSP---IITAAAPPALSPLGELEYPFGAKGDSDPESPL--AAPILETPISP 984
Query: 2366 PPQV----PDGPPDLLLESQWHHYSGEASSSEEEPPSP 2399
PP+ P+ P ++L G AS EP P
Sbjct: 985 PPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPP 1022
Score = 58.9 bits (141), Expect = 7e-08
Identities = 134/580 (23%), Positives = 190/580 (32%), Gaps = 100/580 (17%)
Query: 1837 PIQNLDPPLRPDSGSAPPPA--PRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSL 1894
P +L P +P + +PPPA P F G+ S S G +P P SP L
Sbjct: 2100 PALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGEL 2159
Query: 1895 THHIPTVGD------------PDFPAPPRRSRRPSPLAPRPPPS-RWASPPLKTSPQLRV 1941
+P P +P PR P P P P+ A PP+ +
Sbjct: 2160 FLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGA----- 2214
Query: 1942 PPPTSVVTALTPTSGELAPPGP---APSPPPP--EDLGPDFEDMEVVSGLSAADLDFAAS 1996
+S A P PPG PS P P + P +++ V +
Sbjct: 2215 ---SSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEP 2271
Query: 1997 LLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSA----- 2051
LL PF E + A+ G SS P ++ P + GL
Sbjct: 2272 LLSPPPFGE---SRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFK 2328
Query: 2052 TPGAPRIEQLDGVDDGTDSEAEAVQQPRGQG---TPPSGPGVVRAGVLGAAGDRARPPED 2108
P PR Q++ G + + P Q +PPS P + R G A+PP
Sbjct: 2329 APLTPRASQVEPQSPGLGLRPQ--EPPPAQALAPSPPSHPDIFRPG--SYTDPYAQPP-- 2382
Query: 2109 LPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPG 2168
PR + P PP + + P + L P+DP F+ +P
Sbjct: 2383 --------------------LTPRPQ---PPPPESCCALPPRSL---PSDP---FSRVPA 2413
Query: 2169 APGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTA 2228
+P + S +P P+P +++ + + F P P + P P P
Sbjct: 2414 SP--QSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPR 2471
Query: 2229 PTSWTLPPGPLL--GVLPVVGVVRPAPPP--PPPPLTLVLSSGPASPPRQAIRVKRVSTF 2284
P PP G L + P P P + + P+ P +R F
Sbjct: 2472 PQ----PPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAF 2527
Query: 2285 SGRSPPAPPPYKAPRLDEDGEASEDTPQVPGL----------GSGGFSRVRMKTPTVRGV 2334
G P+P + P+ + PQ PGL G G T
Sbjct: 2528 VG--TPSPMRFTFPQAVGEPSLKPPVPQ-PGLPPPHGINSHFGPGPTLGKPQSTNYTVAT 2584
Query: 2335 LDLDRPGEPAGEE--SPGPLQERSPLLPLPEDGPPQVPDG 2372
+ G P G S G SPL P P PP PDG
Sbjct: 2585 GNFHPSGSPLGPSSGSTGESYGLSPLRP-PSVLPPPAPDG 2623
Score = 57.8 bits (138), Expect = 1e-07
Identities = 165/734 (22%), Positives = 240/734 (32%), Gaps = 125/734 (17%)
Query: 103 PSRGCVPEEESSDGESDEEEFQGFHSDEDVAPSSLRSALRSQRGRA--PRGRGRKHKTTP 160
PS G + DG S+ +E +D P R G+A P K +P
Sbjct: 1797 PSFGLGTPKAKGDGGSERKELPTSQKGDD-GPDIADEESRGLEGKADTPGPEDGGVKASP 1855
Query: 161 LPPPRLADVAPTPPKTPA---------RKRGEEGTERMVQALTELLRRAQAPQAPRSRAC 211
+P P P TP R EE + + L +L + + + C
Sbjct: 1856 VPSD------PEKPGTPGEGMLSSDLDRISTEELPKMESKDLQQLFKDVLGSEREQHLGC 1909
Query: 212 EPSTPRRSRGRPP-GRPAGPCRRKQQAVVVAEAAVTIPKPEPP----PPVVPVKHQTGSW 266
TP R P RP Q + + + P P P + + + G +
Sbjct: 1910 --GTPGLEGSRTPLQRPF-----LQGGLPLGNLPSSSPMDSYPGLCQSPFLDSRERGGFF 1962
Query: 267 KCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGGLPFVIKFVSRAKK-VKMGQLSLGLES 325
+ G P T GG + G G GL + + + R +K ++GQLS
Sbjct: 1963 SPEPGEPDSPWTGS-GGTTPSTPTTPTTEGEGDGLSYNQRSLQRWEKDEELGQLSTISPV 2021
Query: 326 GQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQ---------EQKLDDEEEEKKEEEEKDK 376
QD P Q W+K ++ D+ + + +K
Sbjct: 2022 LYANINFPNLKQDYPDWSSRCKQI-MKLWRKVPAADKAPYLQKAKDNRAAHRINKVQKQA 2080
Query: 377 EGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPV 436
E + ++ V + + ++ L PP P A PPP P+ P P
Sbjct: 2081 ESQINKQTKVGD-IARKTDRPALHLRIPP-QPGALGSPPPAAAPTIFIGSPTTPAGLSTS 2138
Query: 437 SP----PPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGT 492
+ PP S P P + E PP VPA PSQ P G
Sbjct: 2139 ADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQ----------VPSQ---------DPFGL 2179
Query: 493 SPPTPT----PSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMD 548
+P P P+ PP SPT AP P++ A S P F
Sbjct: 2180 APAYPLEPRFPTAPPTYPPYPSPTGAPAQP-----------PMLGASSRPGAGQPGEF-H 2227
Query: 549 EDPPKPPKVEVS---PVLRP--PITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSI 603
PP P+ + S P L+P P + VP+ P +A P +P P E R+++
Sbjct: 2228 TTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPG--VGGGKASEPLLSPPPFGESRKAL 2285
Query: 604 LREPTFRWTSLTRELPP-----------------PPPAPPPPPAPSPPPAPATSSRRPLL 646
+ S PP P AP P A + P L
Sbjct: 2286 EVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGL 2345
Query: 647 LRAPQFTP--------SEAHLKIYE-SVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVG 697
PQ P +H I+ T P P P P+PPP + A P PR+
Sbjct: 2346 GLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALP-PRS-- 2402
Query: 698 RTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQ 757
L F+ V +P S +P +A P+ P + PP +
Sbjct: 2403 ----LPSDPFSRVPASPQSQSSSQ--SPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSR 2456
Query: 758 PQLQPPPSPQQMPP 771
PQ + P +P PP
Sbjct: 2457 PQSRDPFAPLHKPP 2470
Score = 57.4 bits (137), Expect = 2e-07
Identities = 162/658 (24%), Positives = 209/658 (31%), Gaps = 139/658 (21%)
Query: 1807 SPAPSSEPPGG------EDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSF 1860
+P P PP P D VP +P+ S Q+ P RP S A P+P +
Sbjct: 2384 TPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTP-RPLSAEAFCPSPVT- 2441
Query: 1861 SGARIKVPN-YS-PSRRPLGGVSFGPLPSPGSPS---------SLTHHIPTVGDPDFPA- 1908
R + P+ YS P RP F PL P P SL H ++G FPA
Sbjct: 2442 --PRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAH--TSLGAGGFPAA 2497
Query: 1909 -PPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSP 1967
P + P P + P T + P P L PP P P
Sbjct: 2498 LPAGPAGELHAKVPSGQPPNFVRSP-GTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGL 2556
Query: 1968 PPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHG--GPGDSSE 2025
PPP + F LG VA G S GP S
Sbjct: 2557 PPPHGINSHFG---------------PGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGST 2601
Query: 2026 EESSPTSRYIHFPVTVVSAP-GLAPSATPGAPR-------IEQLDGVDDGTDSEAEAVQQ 2077
ES S V AP G P + GA + +E+ + G S +
Sbjct: 2602 GESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAEL 2661
Query: 2078 PRGQGTPPSGPGVVRAGVLGAAGDRARPPEDL------------PSEIVDFVLKNLGGPG 2125
P GT G + L R R E L E +G PG
Sbjct: 2662 P---GTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPG 2718
Query: 2126 DGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLS--LGPA--- 2180
GA P S P L+ G P G T+ + L G P ++ LGP
Sbjct: 2719 SWGAEP---SSPAFEQLSRGQTPFAG--------TQDKSSLVGLPPSKLSGPILGPGSFP 2767
Query: 2181 -----PEPPKPATSKIILVNKL-----GQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPT 2230
PP PAT + VN Q F + A +P +Q L TA T
Sbjct: 2768 SDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAAT 2827
Query: 2231 S--------WTLPPGPLLG----VLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRV 2278
S + PGP LG P+ G+ P P P GPA P Q I +
Sbjct: 2828 SMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEP------VPGPAG-PAQFIEL 2880
Query: 2279 KR---------VSTFSGRSPPAPPPYKAPRLDEDGEASE---------------DTPQVP 2314
+ + F G+ PP P + D A E P P
Sbjct: 2881 RHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAP 2940
Query: 2315 GLGSGGFSRVRMKTPTVRGVLDL-DRPGEPAGEESPGPLQERSPLLPLPEDGPPQVPD 2371
L + K PT+ L+L +RP P PL + LP + P++ D
Sbjct: 2941 ELNNSLHPTPHTKGPTLPTGLELVNRPPSSTELGRPNPLALEAGKLPCED---PELDD 2995
Score = 54.3 bits (129), Expect = 2e-06
Identities = 76/306 (24%), Positives = 108/306 (35%), Gaps = 53/306 (17%)
Query: 390 MMPAAEKEEAKLP--------PPPLTPPAPSPP--PPL--PPPSTSP--PPPLCPPPPPP 435
+ P A + E + P PPP APSPP P + P T P PPL P P PP
Sbjct: 2331 LTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPP 2390
Query: 436 -------VSPPPLPSPP---PPPAQEEQEESPPPVVPATCSRKRGRP-PLTPSQRAEREA 484
+ P LPS P P + + Q S P+ P S + P P+TP ++
Sbjct: 2391 PPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPY 2450
Query: 485 AR--AGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKN-----------IRQFIMPV 531
+R + P+ P P PPE + + T L + V
Sbjct: 2451 SRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKV 2510
Query: 532 VSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPS 591
S + +++P P P + + P + PPVPQ P P + P
Sbjct: 2511 PSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEP-SLKPPVPQPGLPPPHGINSHFGPG 2569
Query: 592 TPVPLPEKRRSILREPTFR--------WTSLTRE------LPPPPPAPPPPPAPSPPPAP 637
+ P+ + F + T E L PP PPP P S P
Sbjct: 2570 PTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLS 2629
Query: 638 ATSSRR 643
+S+R
Sbjct: 2630 HGASQR 2635
Score = 53.9 bits (128), Expect = 2e-06
Identities = 139/594 (23%), Positives = 195/594 (32%), Gaps = 139/594 (23%)
Query: 1792 PAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGS 1851
PA L A + +H+ PS +PP P + +P R + Q + P S
Sbjct: 2495 PAALPAGPAGE--LHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEP------S 2546
Query: 1852 APPPAPRSFSGARIKVPNYSPSRRPLGGVS--FGPLPSPGSPSSLTHHIPT-----VGDP 1904
PP P+ P P G++ FGP P+ G P S + + T G P
Sbjct: 2547 LKPPVPQ-------------PGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSP 2593
Query: 1905 DFPAPPR--RSRRPSPLAPR---PPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELA 1959
P+ S SPL P PPP+ S P + + TS V +
Sbjct: 2594 LGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMG 2653
Query: 1960 PPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLD-----------FAASLLGTEPFQEEIV 2008
P +D G +SGLS +L+ + ++E
Sbjct: 2654 SSLATAELPGTQDPG--------MSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKE 2705
Query: 2009 AAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGT 2068
A A + G PG E SSP L+ TP A GT
Sbjct: 2706 TAAAAAGAVGPPGSWGAEPSSPAFEQ------------LSRGQTPFA-----------GT 2742
Query: 2069 DSEAEAVQQPRGQGTPPS---GPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPG 2125
++ V G PPS GP ++ G + +RPP +D + L G
Sbjct: 2743 QDKSSLV------GLPPSKLSGP-ILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGS 2795
Query: 2126 DGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPK 2185
A + P + PL Q + A A +R P P
Sbjct: 2796 Q--AFYQRAPYPGSLPLQQQQQQLWQQQQATA-----------ATSMRFAMSARFPSTPG 2842
Query: 2186 PATSKIILVNKLGQVFVKMAGEGEPVPPPV-------------------------KQPPL 2220
P + L + L + ++ G GEPVP P + PP
Sbjct: 2843 PELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQ 2902
Query: 2221 PPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAP-PPPPPPLTLVL-----SSGPASPP-R 2273
P P + L P L G L V G+ P PP P L L + GP P
Sbjct: 2903 RPRFYPVSEDPHRLAPEGLRG-LAVSGLPPQKPSAPPAPELNNSLHPTPHTKGPTLPTGL 2961
Query: 2274 QAIRVKRVSTFSGRSPP-----APPPYKAPRLDEDGEAS---EDTPQVPGLGSG 2319
+ + ST GR P P + P LD+D +A ED ++ LG G
Sbjct: 2962 ELVNRPPSSTELGRPNPLALEAGKLPCEDPELDDDFDAHKALEDDEELAHLGLG 3015
Score = 53.1 bits (126), Expect = 4e-06
Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 1/87 (1%)
Query: 1602 GQNEWTHVNCAIWSAEVFEENDGSLKNVHAAVARGRQMRCELCLKPGATVGCCLSSCLSN 1661
G + W H CA WSA V+ + L V A+ G RC C + GA++ C C
Sbjct: 133 GGSCWAHHWCAAWSAGVWGQEGPELCGVDKAIFSGISQRCSHCTRLGASIPCRSPGCPRL 192
Query: 1662 FHFMCARAS-YCIFQDDKKVFCQKHTD 1687
+HF CA AS + ++ C +H++
Sbjct: 193 YHFPCATASGSFLSMKTLQLLCPEHSE 219
Score = 52.8 bits (125), Expect = 5e-06
Identities = 123/511 (24%), Positives = 170/511 (33%), Gaps = 82/511 (16%)
Query: 1911 RRSRRPSPLAPRPP-PSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPP-GPAPSPP 1968
R++ RP+ PP P SPP +P + + PT+ T G L PP G P P
Sbjct: 2095 RKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPD 2154
Query: 1969 PPEDLG---PDFEDMEVVS----GLSAA---DLDFAASLLGTEPFQEEIVAAGAM----G 2014
P +L P +V S GL+ A + F + P+ A
Sbjct: 2155 SPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGA 2214
Query: 2015 SSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQL-----DGVDDGTD 2069
SS G G E ++P H P T P P P ++ L GV G
Sbjct: 2215 SSRPGAGQPGEFHTTPPGTPRHQPSTP------DPFLKPRCPSLDNLAVPESPGVGGGKA 2268
Query: 2070 SEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGA 2129
SE P G+ V+ LGA+ PP + FV G GG
Sbjct: 2269 SEPLLSPPPFGESRKAL---EVKKEELGASSPSYGPPN------LGFVDSPSSGTHLGGL 2319
Query: 2130 GPREESLPPAP--PLANGSQP-SQGLTASPADPTRTFAWLPGAPGVRVL----------- 2175
+ + AP P A+ +P S GL P +P A P P +
Sbjct: 2320 ELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYA 2379
Query: 2176 --SLGPAPEPPKPAT-----SKIILVNKLGQVFVKMAGEGEPVPPPVKQP-------PLP 2221
L P P+PP P + + + + +V + P +P P P
Sbjct: 2380 QPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSP 2439
Query: 2222 PTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKRV 2281
T +P ++ PP P + +P P P PP + S +
Sbjct: 2440 VTPRFQSPDPYSRPPSRPQSRDPFAPLHKP-PRPQPPEVAFKAGS-----------LAHT 2487
Query: 2282 STFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGF----SRVRMKTPTVRGVLDL 2337
S +G P A P A L + + V G+G F S +R P G L
Sbjct: 2488 SLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSL 2547
Query: 2338 DRPGEPAGEESPGPLQERSPLLPLPEDGPPQ 2368
P G P P S P P G PQ
Sbjct: 2548 KPPVPQPG--LPPPHGINSHFGPGPTLGKPQ 2576
Score = 51.6 bits (122), Expect = 1e-05
Identities = 129/541 (23%), Positives = 186/541 (34%), Gaps = 152/541 (28%)
Query: 407 TPPAPSPPPPLPPPSTSPPPPLC---PPPPPPVSPPPLPSPPPPPAQEEQ---------- 453
TP + + P PS S L P P P S L P P Q++Q
Sbjct: 4054 TPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGG 4113
Query: 454 ------------EESPPPVVPATCSRKRGRPP------LTPSQRAEREAARAGPEGTSPP 495
E S P + A S G P L Q+ E G PP
Sbjct: 4114 GSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPP 4173
Query: 496 TPTPSTATG--------------------GPPEDSPTVAPKSTTFLKNIRQFIMPVVSAR 535
P P +G G +P + S + ++ +M +
Sbjct: 4174 KPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQ 4233
Query: 536 SSRVIKTPRRFMDEDPPKPPKVEVSPVLR-----------PPITTSP-------PVPQEP 577
S V +TP P + P + SP+ P T P P PQ P
Sbjct: 4234 SQAVRQTP-------PYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGP 4286
Query: 578 APVPSPPRA-----------PTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPP 626
+P+PP A PTPP + P KR S L P+ + + +LPP P P
Sbjct: 4287 PRLPAPPGALSTGPVLGPVHPTPPPSS-PQEPKRPSQLPSPSSQLPT-EAQLPPTHPGTP 4344
Query: 627 PPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHL--KIYESVLTP--PPLGAPEAPEPE-- 680
P P+ P P + +P+ A L ++ L P PP E +PE
Sbjct: 4345 KPQGPTLEPPPG------------RVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQS 4392
Query: 681 ---PPPADDSPAEPEPRAVGRTNHLSL---PRFAPVV--TTPVKAEVS--PHGAPALSN- 729
P D + P A + LS+ PR P VK E + P GAP SN
Sbjct: 4393 SLVPGHLDQVNGQVVPEA----SQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNH 4448
Query: 730 ----GPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGVGSLPL 785
GP+++A L LL + L QL + + +A I G L
Sbjct: 4449 LLLAGPRSEAGHL---------LLQKLLRAKNVQLSTGRGSEGL----RAEINGHIDSKL 4495
Query: 786 SGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISDRGPVRSE 845
+G+E+K+ + ++ AA PL+P + + A + + +S R +R E
Sbjct: 4496 AGLEQKL------------QGTPSNKEDAAARKPLTPKPKRVQKA-SDRLVSSRKKLRKE 4542
Query: 846 D 846
D
Sbjct: 4543 D 4543
Score = 50.4 bits (119), Expect = 2e-05
Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 1/74 (1%)
Query: 400 KLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPP 459
+L PP P+P P P P P++ P PL P P++ PP+PSP P + E P
Sbjct: 4905 QLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPR 4964
Query: 460 VVPATCSRKRGRPP 473
P + RPP
Sbjct: 4965 ARPPE-EGEDSRPP 4977
Score = 49.7 bits (117), Expect = 4e-05
Identities = 129/564 (22%), Positives = 190/564 (33%), Gaps = 108/564 (19%)
Query: 635 PAPATSSRRPLLLRAPQFTPS-EAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEP 693
P P +PL Q P EA L E L PPP +P +P PE +SP P P
Sbjct: 409 PGPLQCEAKPLGKAGVQLEPQLEAPLN-EEMPLLPPPEESPLSPPPE-----ESPTSPPP 462
Query: 694 RAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQA-QLLQPLQALQTQLLPQA 752
A + LS P P PA P +A L +PL+ P +
Sbjct: 463 EA----SRLSPP---------------PEELPA---SPLPEALHLSRPLEES-----PLS 495
Query: 753 LPPPQPQLQPPPSPQQMPPLEKARIAGVGSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQ 812
PP + L PPP PLE++ ++ P S E S A ++
Sbjct: 496 PPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLS 555
Query: 813 KVAASMPLSPGGQMEEVAGAVKQISDRGPVRSEDES--VEAKRERPSGPESPVQGP---- 866
+P SP + ++ ++ P S EA R P ESP+ P
Sbjct: 556 PPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEES 615
Query: 867 ---------RIKHVCRHAAVALGQARAMV--PEDVPRLSALPLRDRQDLATEDTSSASET 915
R+ + ++ + + P +V RLS LP+ R E++ +
Sbjct: 616 PLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPP 675
Query: 916 ESVPSRSRRGKVEAAGPGGESEPTG---SGGTLAHTPRRSLPSHHGKKMRMARCGHCRGC 972
E P+ S + P E PT + P SL S ++ +
Sbjct: 676 EESPT-SPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPE---- 730
Query: 973 LRVQDCGSCVNCLDKPKFGGPNTKKQCCVYRKCDKIEARKMERLAKKGRTIVKTLLPWDS 1032
Q C P+ GP+ + + E + A++ L P
Sbjct: 731 -EPQLC---------PRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPH-----LSP--Q 773
Query: 1033 DESPEASPGPPGPRRGAGAGGPR-----EEVVAHPGPEE----------------QDSLL 1071
E P P P A GP EE+ P EE ++S L
Sbjct: 774 PEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHL 833
Query: 1072 QRKSARRCVKQRP-----SYDIFEDSDDSEPGGPPAPRRRTPRENELPLPEPEEQSRPRK 1126
+S C+ RP S ++ + P PP + P ELPL P P +
Sbjct: 834 SPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPP-----PGE 888
Query: 1127 PTLQPVLQLKARRRLDKDALAPGP 1150
P+L P+L A + L+P P
Sbjct: 889 PSLSPLLGEPALSEPGEPPLSPLP 912
Score = 48.1 bits (113), Expect = 1e-04
Identities = 63/226 (27%), Positives = 84/226 (37%), Gaps = 39/226 (17%)
Query: 392 PAAEKEEAKLPPPPLTPPAP-SPPPPLPPPSTSPPPPLCPPP-----PPPVSPPPLPSPP 445
P A + + PP + PP+P SP P P P PP C P P SPP SPP
Sbjct: 986 PEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPP 1045
Query: 446 PPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGG 505
P SP V S + + + +E E P TSP P+P
Sbjct: 1046 ALPLSVPSPLSPIGKVVGV-SDEAELHEMETEKVSEPECPALEPSATSP-LPSPMGDLSC 1103
Query: 506 PPEDSPTVAPKSTTFLKNIRQFIMPV--VSARSSRVI--KTPRRFMDEDPPKPPKVEVSP 561
P +P+ AP F + + P+ + A S+ +TP E ++ SP
Sbjct: 1104 P---APSPAPALDDF-SGLGEDTAPLDGIDAPGSQPEPGQTPGSLASE-------LKGSP 1152
Query: 562 VLRPPITTSPPVPQEPAPV----------------PSPPRAPTPPS 591
VL P +P P E P P P APTPP+
Sbjct: 1153 VLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPT 1198
Score = 47.0 bits (110), Expect = 3e-04
Identities = 114/484 (23%), Positives = 166/484 (34%), Gaps = 82/484 (16%)
Query: 403 PPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPL-PSPPPPPAQEEQEESPPPVV 461
PPP +P P P LP PS+ P PP P +P P P+ PPP + SP
Sbjct: 4309 PPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGR----VSPAAAQ 4364
Query: 462 PATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFL 521
A +G P P + A PE + S G + + V P+++
Sbjct: 4365 LADTLFSKGLGPWDP---PDNLAETQKPEQS-------SLVPGHLDQVNGQVVPEASQL- 4413
Query: 522 KNIRQFIMPVVSARSSRVIKTPRRFMDEDPP--------KPPKVEVSPVLRPPITTSPPV 573
+I+Q A ++ +K P P+ E +L + + V
Sbjct: 4414 -SIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNV 4472
Query: 574 PQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSP 633
RA L + + P+ + + R+ P P P
Sbjct: 4473 QLSTGRGSEGLRAEINGHIDSKLAGLEQKLQGTPSNKEDAAARK-----PLTPKPKRVQK 4527
Query: 634 PPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEP 693
SSR+ L + SEA LK + L+ PL P
Sbjct: 4528 ASDRLVSSRKK-LRKEDGVRASEALLKQLKQELSLLPLTEPAI----------------- 4569
Query: 694 RAVGRTNHLSLPRFAPVVT-TPVKAEVSPHGA---PALSNGPQTQAQLLQPLQALQTQLL 749
T + SL FAP + PV + GA AL GP +QLL
Sbjct: 4570 -----TANFSL--FAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPTP 4622
Query: 750 PQALPPPQPQLQPPPSPQQMPPLEKARIAGVGSLPLSGVEEKMFSLLKRAKVQLFKIDQQ 809
P +LPP PPPS QQ + GV G K + + ++ L +
Sbjct: 4623 PSSLPP-----TPPPSVQQ------KMVNGVTPSEELGEHPKDAASARDSERALRDTSEV 4671
Query: 810 QQQKVAASMPLSPGGQMEEVAGAVKQISDRGPVRSEDESVEAKRERPSGPESPV--QGPR 867
+ + A++P P Q E+V + SD S D V A S PES + + PR
Sbjct: 4672 KSLDLLAALPTPPHNQTEDVRMESDEDSD-----SPDSIVPA-----SSPESILGEEAPR 4721
Query: 868 IKHV 871
H+
Sbjct: 4722 FPHL 4725
Score = 44.3 bits (103), Expect = 0.002
Identities = 80/358 (22%), Positives = 117/358 (32%), Gaps = 67/358 (18%)
Query: 367 EKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPP--------LTPPAPSPPPPLP 418
E+ E KD ERA+ + + A LP PP + S P
Sbjct: 4646 EELGEHPKDAASARDSERALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSI 4705
Query: 419 PPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQ 478
P++SP L P P L S E+++ + PV+P R P+ P
Sbjct: 4706 VPASSPESILGEEAP---RFPHLGSG----RWEQEDRALSPVIPLI---PRASIPVFPDT 4755
Query: 479 RAEREAARAGPEGTSPPTPTPSTA-TGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSS 537
+ G G P P T G + + S KN+ ++ V S
Sbjct: 4756 KPY------GALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSM 4809
Query: 538 RVIKTPRRFMDEDPPK------------PPKVEVSPVLRPPITTSPPVPQEPAPVPSPPR 585
++ + E P + P E + P T + Q A +P
Sbjct: 4810 KIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTL 4869
Query: 586 APT-------PPSTPVPLPEKRRSILREPTFRWTSL-TRELPPPPPAPPPPPAPSPPPAP 637
+P P P + S T+ ++L R+L PPP P PP P+P
Sbjct: 4870 KSQLDILSLLKQESPAPEPPTQHSY----TYNVSNLDVRQLSAPPPEEPSPPPSPLAPSP 4925
Query: 638 ATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRA 695
A+ PL+ L PL P P P P + A P+PRA
Sbjct: 4926 ASPPTEPLV------------------ELPTEPLAEPPVPSPLPLASSPESARPKPRA 4965
Score = 43.5 bits (101), Expect = 0.003
Identities = 159/671 (23%), Positives = 213/671 (31%), Gaps = 150/671 (22%)
Query: 1832 PERHSPIQNL--DPPLRPD---SGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLP 1886
P+ P Q L PP PD GS P + P +P +P S LP
Sbjct: 2349 PQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQ---------PPLTPRPQPPPPESCCALP 2399
Query: 1887 SPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTS 1946
PS +P +P +S SPL PRP + A P +P+ + P P S
Sbjct: 2400 PRSLPSDPFSRVPA-------SPQSQSSSQSPLTPRPLSAE-AFCPSPVTPRFQSPDPYS 2451
Query: 1947 VVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEE 2006
+ + AP P P PPE A L A + LG F
Sbjct: 2452 RPPSRPQSRDPFAPLHKPPRPQPPE------------VAFKAGSL--AHTSLGAGGFPAA 2497
Query: 2007 IVAAGAMGSSHG------------GPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPG 2054
+ AG G H PG + +P+ FP V P PG
Sbjct: 2498 L-PAGPAGELHAKVPSGQPPNFVRSPG-TGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPG 2555
Query: 2055 APRIEQLD---------GVDDGTD-SEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRAR 2104
P ++ G T+ + A P G PS + L R
Sbjct: 2556 LPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSP----LR 2611
Query: 2105 PPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFA 2164
PP LP D L L GA R P+ P G+ +S A A
Sbjct: 2612 PPSVLPPPAPDGSLPYL----SHGASQRSGI---TSPVEKREDPGTGMGSSLAT-----A 2659
Query: 2165 WLPGA--PGVRVLSLGPAPEPPKPATSKIILV------NKLGQVFVKMAGEGEPVPPP-- 2214
LPG PG+ LS + + + +L+ N L Q A V PP
Sbjct: 2660 ELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGS 2719
Query: 2215 ----VKQPPLPPTISPTAPTSWT--------LPPGPLLGVLPVVGVVR-------PAPPP 2255
P P + T LPP L G P++G PPP
Sbjct: 2720 WGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSG--PILGPGSFPSDDRLSRPPP 2777
Query: 2256 PPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSP---PAPPPYKAPRLDEDGEASEDT-- 2310
P P ++ ++S QA F R+P P + +L + +A+ T
Sbjct: 2778 PATPSSMDVNSRQLVGGSQA--------FYQRAPYPGSLPLQQQQQQLWQQQQATAATSM 2829
Query: 2311 --------PQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPA-GEESPGPLQERSPLL-- 2359
P PG G R + +P L PGEP G P E +
Sbjct: 2830 RFAMSARFPSTPGPELG---RQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQK 2886
Query: 2360 -------PLPEDGPPQVP------DGPPDLLLES-QWHHYSGEASSSEEEPPSPD--DKE 2403
P P GPPQ P + P L E + SG PP+P+ +
Sbjct: 2887 GLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSL 2946
Query: 2404 NQAPKRTGPHL 2414
+ P GP L
Sbjct: 2947 HPTPHTKGPTL 2957
Score = 43.5 bits (101), Expect = 0.003
Identities = 81/359 (22%), Positives = 119/359 (33%), Gaps = 80/359 (22%)
Query: 340 PQRRVGSGQGGSPCWKKQEQKLDDEEEEKK-----------EEEEKDKEGEEKEERAVAE 388
P +G + + E+ L D E K + +D E E+ +
Sbjct: 4644 PSEELGEHPKDAASARDSERALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPD 4703
Query: 389 EMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPP-------- 440
++PA+ E P P S + SP PL P PV P
Sbjct: 4704 SIVPASSPESILGEEAPRFPHLGSGRWEQEDRALSPVIPLIPRASIPVFPDTKPYGALGL 4763
Query: 441 -LPSPPPPPAQEEQEESPPPVV----PATCSRKRG-----------RPPLTPSQRAEREA 484
+P P E+ + S V+ A G + P +
Sbjct: 4764 EVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESP 4823
Query: 485 ARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQF--IMPVVSARSSRVIKT 542
ARAG E P G SP P ++QF ++P + +S I +
Sbjct: 4824 ARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDW------LKQFDAVLPGYTLKSQLDILS 4877
Query: 543 PRRFMDEDPPKPP----------KVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPST 592
+ + P+PP ++V + PP P+EP+P PSP AP+P S
Sbjct: 4878 LLK-QESPAPEPPTQHSYTYNVSNLDVRQLSAPP-------PEEPSPPPSP-LAPSPASP 4928
Query: 593 PVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQ 651
P EP ELP P A PP P+P P + S+R R P+
Sbjct: 4929 PT-----------EPLV-------ELPTEPLAEPPVPSPLPLASSPESARPKPRARPPE 4969
Score = 42.7 bits (99), Expect = 0.005
Identities = 32/97 (32%), Positives = 41/97 (42%), Gaps = 18/97 (18%)
Query: 1884 PLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRR--PSPLAPRPPPSRWASPP------LKT 1935
P P P + S T+++ + APP PSPLAP P ASPP L T
Sbjct: 4884 PAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSP-----ASPPTEPLVELPT 4938
Query: 1936 SPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPED 1972
P P P+ + A +P S P P PPE+
Sbjct: 4939 EPLAEPPVPSPLPLASSPESAR-----PKPRARPPEE 4970
Score = 42.4 bits (98), Expect = 0.006
Identities = 33/105 (31%), Positives = 41/105 (39%), Gaps = 12/105 (11%)
Query: 396 KEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPP-PVSPPPLPSPPPPPAQEEQE 454
K+E+ P PP L S PPP P PPP P++P P P P + E
Sbjct: 4880 KQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTE 4939
Query: 455 ESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGP----EGTSPP 495
P VP+ PL S + R RA P E + PP
Sbjct: 4940 PLAEPPVPSPL-------PLASSPESARPKPRARPPEEGEDSRPP 4977
Score = 41.6 bits (96), Expect = 0.011
Identities = 101/457 (22%), Positives = 145/457 (31%), Gaps = 98/457 (21%)
Query: 249 KPEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGR------------GGRGRG 296
KP P P +P H S GPGP G P+ + G G G
Sbjct: 2548 KPPVPQPGLPPPHGINS---HFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGES 2604
Query: 297 RG----------------GGLPFVIKFVSRAKKVKMGQLSLGLESGQGQGQHEESWQDVP 340
G G LP++ S+ + + + G G G + +
Sbjct: 2605 YGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGIT-SPVEKREDPGTGMGSSLATAELPG 2663
Query: 341 QRRVGSGQGGSPCWKKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVA------------E 388
+ G +KQ Q+ E +++ +++ +EKE A A E
Sbjct: 2664 TQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAE 2723
Query: 389 EMMPAAEKEEAKLPPPPLT---------PPAPSPPPPLPPPSTSPPPPLCPPPPPPV--- 436
PA E+ P T PP+ P L P S L PPPP
Sbjct: 2724 PSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSS 2783
Query: 437 ----------------SPPPLPSPPPPPAQEEQEESPPPVVPATCSR--KRGRPPLTPSQ 478
P P P Q++Q AT R R P TP
Sbjct: 2784 MDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGP 2843
Query: 479 RAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSR 538
R+A + G S P P G P P + N+++ + P
Sbjct: 2844 ELGRQALGSPLAGISTRLPGP-----GEPVPGPAGPAQFIELRHNVQKGLGPG------- 2891
Query: 539 VIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPE 598
TP F + PP+ P+ PV P +P + A PP+ P+ P P PE
Sbjct: 2892 --GTP--FPGQGPPQRPR--FYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAP----PAPE 2941
Query: 599 KRRSILREPTFRWTSLTR--ELPPPPPAPPPPPAPSP 633
S+ P + +L EL PP+ P+P
Sbjct: 2942 LNNSLHPTPHTKGPTLPTGLELVNRPPSSTELGRPNP 2978
Score = 41.6 bits (96), Expect = 0.011
Identities = 29/74 (39%), Positives = 37/74 (50%), Gaps = 7/74 (9%)
Query: 391 MPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPP---PVSPPPLPSPPPP 447
+ A EE PP PL P+P+ PP P P PL PP P P++ P + P P
Sbjct: 4906 LSAPPPEEPSPPPSPL-APSPA-SPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKP 4963
Query: 448 PAQ--EEQEESPPP 459
A+ EE E+S PP
Sbjct: 4964 RARPPEEGEDSRPP 4977
Score = 41.2 bits (95), Expect = 0.014
Identities = 103/447 (23%), Positives = 149/447 (33%), Gaps = 79/447 (17%)
Query: 1879 GVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASP-PLKTSP 1937
G+ PL SP +L + G P S A P + P + T+P
Sbjct: 4000 GMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSE----ATEGPSTHQGGPLAIGTTP 4055
Query: 1938 QLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASL 1997
+ P V +L+ S +L P P P P S+ L L
Sbjct: 4056 ESMATEPGEVKPSLSGDS-QLLLVQPQPQPQP-----------------SSLQLQPPLRL 4097
Query: 1998 LGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFP-VTVVSAPGLAPSAT--PG 2054
G + Q ++ A G SHG G S E+S + P V++ PG P
Sbjct: 4098 PGQQQQQVSLLHT-AGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQ 4156
Query: 2055 APRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIV 2114
P +E+ + G Q P+ SG G+ G++ G L +++
Sbjct: 4157 QPMLERPMQNNTGP-------QPPKPGPVLQSGQGLPGVGIMPTVGQ-------LRAQLQ 4202
Query: 2115 DFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPA--DPTRTFAWLPGAPGV 2172
+ KN P P+++ A + Q SQ + +P +P + L G G
Sbjct: 4203 GVLAKN---PQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGC 4259
Query: 2173 RVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSW 2232
+ LG P P ++ G G P P P LP
Sbjct: 4260 QP-QLGGFPGPQTGPLQEL--------------GAG---PRPQGPPRLPA---------- 4291
Query: 2233 TLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAP 2292
PPG L PV+G V P PPP P S P+ + + T G P
Sbjct: 4292 --PPGAL-STGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQG 4348
Query: 2293 PPYKAP--RLDEDGEASEDTPQVPGLG 2317
P + P R+ DT GLG
Sbjct: 4349 PTLEPPPGRVSPAAAQLADTLFSKGLG 4375
Score = 41.2 bits (95), Expect = 0.014
Identities = 37/160 (23%), Positives = 55/160 (34%), Gaps = 26/160 (16%)
Query: 392 PAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPL---------- 441
P K ++LP P P + PP P + P P PPP VSP
Sbjct: 4314 PQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKG 4373
Query: 442 --PSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGP---------- 489
P PP E Q+ +VP + G+ SQ + ++ R P
Sbjct: 4374 LGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKR 4433
Query: 490 EGTSPPTPTPSTAT----GGPPEDSPTVAPKSTTFLKNIR 525
E P P T+ GP ++ + + KN++
Sbjct: 4434 EANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQ 4473
Score = 37.4 bits (85), Expect = 0.20
Identities = 48/165 (29%), Positives = 65/165 (39%), Gaps = 38/165 (23%)
Query: 2134 ESLPPAPPLANGSQPSQGLTASPADPTRTF----------------AWLPG---APGVRV 2174
E L P P G++P +G P + A LPG + +
Sbjct: 4816 EVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDI 4875
Query: 2175 LSL----GPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPT 2230
LSL PAPEPP + + N + V+ PP ++P PP SP AP+
Sbjct: 4876 LSLLKQESPAPEPPTQHSYTYNVSN----LDVRQLSA-----PPPEEPSPPP--SPLAPS 4924
Query: 2231 SWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQA 2275
+ P PL+ LP + A PP P PL L S A P +A
Sbjct: 4925 PASPPTEPLV-ELPTEPL---AEPPVPSPLPLASSPESARPKPRA 4965
Score = 37.0 bits (84), Expect = 0.27
Identities = 36/105 (34%), Positives = 42/105 (40%), Gaps = 25/105 (23%)
Query: 1872 PSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPP-RRSRRP--SPLAPRPPPSRW 1928
P PL + GP P G P PAPP S P P+ P PPPS
Sbjct: 4269 PQTGPLQELGAGPRPQ--------------GPPRLPAPPGALSTGPVLGPVHPTPPPS-- 4312
Query: 1929 ASPPLKTSPQLRVPPPTSVV---TALTPT-SGELAPPGPAPSPPP 1969
SP P ++P P+S + L PT G P GP PPP
Sbjct: 4313 -SPQEPKRPS-QLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPP 4355
Score = 36.6 bits (83), Expect = 0.35
Identities = 78/356 (21%), Positives = 127/356 (35%), Gaps = 85/356 (23%)
Query: 188 RMVQALTE------LLRRAQ-APQAPRSR---ACEPSTPRRSRGRPP--------GRPAG 229
R+V++ E LLR + P P R A + S PR + P GR
Sbjct: 3071 RLVESANEKAEREALLRGVEPGPLGPEERPPPAADASEPRLASVLPEVKPKVEEGGRHPS 3130
Query: 230 PCRRKQQAVVVAEAAVTIPKPEPPPP-------VVPVKHQTGSWKCKEGPGPGPGTPRRG 282
PC + + PK EP P + P + GS + G GP +
Sbjct: 3131 PC----------QFTIATPKVEPAPAANSLGLGLKPGQSMMGSRDTRMGTGPFSSSGHTA 3180
Query: 283 GQSSRGGRGGRGR---------GRGGGLPFVIKFVSRAKKVKMGQLSLGLESGQGQGQHE 333
++S G GG G GG S +K ++ +L L G E
Sbjct: 3181 EKASFGATGGPPAHLLTPSPLSGPGGS--------SLLEKFELESGALTLPGGPAASGDE 3232
Query: 334 ESWQDVPQRRVGSGQGGSPCWKKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPA 393
++ S S E L E EKKE ++K + ++ ++ PA
Sbjct: 3233 LD-------KMESSLVASELPLLIEDLL---EHEKKELQKKQQ---------LSAQLQPA 3273
Query: 394 AEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPP---------LCPPPPPPVSPPPLPSP 444
++++ + L+ P P+ LP +SP L P + P +P+
Sbjct: 3274 QQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQLSLGLAGARQPGLPQPLMPTQ 3333
Query: 445 PPPPAQEEQEESPPPVVP----ATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPT 496
PP A +++ +V + G+ L P Q ++ ++ P GT PP+
Sbjct: 3334 PPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQSSQPVLSQK-PMGTMPPS 3388
Score = 36.6 bits (83), Expect = 0.35
Identities = 124/532 (23%), Positives = 176/532 (33%), Gaps = 106/532 (19%)
Query: 1792 PAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQN-LDPPLRPDSG 1850
P L +E T+ PA SSE G + + PE + + P L DS
Sbjct: 4017 PTLLLTGKEQNTV--DPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQ 4074
Query: 1851 SA---PPPAPRSFSGARIKVPNYSPSRRP--------LGGVSFGPLPSPGSP--SSLTHH 1897
P P P+ S +++ P P ++ GG S G L S S SS+ H
Sbjct: 4075 LLLVQPQPQPQP-SSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHL 4133
Query: 1898 I--PTVGDPDFPAPPRRSRR--PSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTP 1953
+ P+V D P ++ P+ RP + P K P L+ V + P
Sbjct: 4134 LAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGV-GIMP 4192
Query: 1954 TSGELAPP--GPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAG 2011
T G+L G P L P + ++ + L L + ++ T P+QE
Sbjct: 4193 TVGQLRAQLQGVLAKNPQLRHLSPQ-QQQQLQALLMQRQLQQSQAVRQTPPYQE------ 4245
Query: 2012 AMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGA----PRIEQLDGVDDG 2067
PG S G P++ G G
Sbjct: 4246 ---------------------------------PGTQTSPLQGLLGCQPQLGGFPGPQTG 4272
Query: 2068 TDSEAEAVQQPRGQGTPPSGPGVVRAG-VLGAAGDRARPPEDLPSEIVDFVLKNLGGPGD 2126
E A +P+G P+ PG + G VLG PP P E + P
Sbjct: 4273 PLQELGAGPRPQGPPRLPAPPGALSTGPVLGPV--HPTPPPSSPQE----PKRPSQLPSP 4326
Query: 2127 GGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGP------A 2180
P E LPP P G+ QG T P + A A + LGP
Sbjct: 4327 SSQLPTEAQLPPTHP---GTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNL 4383
Query: 2181 PEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLL 2240
E KP S ++ L QV ++ E + +KQ P P A L
Sbjct: 4384 AETQKPEQSSLV-PGHLDQVNGQVVPEASQL--SIKQEPRE---EPCA-----------L 4426
Query: 2241 GVLPVVGVVRPAPPPPPPPLTLVLSSGPASPP-----RQAIRVKRVSTFSGR 2287
G V P P +L +GP S ++ +R K V +GR
Sbjct: 4427 GAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGR 4478
Score = 36.2 bits (82), Expect = 0.45
Identities = 36/117 (30%), Positives = 42/117 (35%), Gaps = 23/117 (19%)
Query: 405 PLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPAT 464
PL P P PP +PP L P V P P+PPP QE + S P
Sbjct: 4273 PLQELGAGPRPQGPPRLPAPPGALSTGP---VLGPVHPTPPPSSPQEPKRPSQLP----- 4324
Query: 465 CSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPED--SPTVAPKSTT 519
+PS + EA T P TP P T PP SP A + T
Sbjct: 4325 ----------SPSSQLPTEAQL---PPTHPGTPKPQGPTLEPPPGRVSPAAAQLADT 4368
Score = 36.2 bits (82), Expect = 0.45
Identities = 34/107 (31%), Positives = 42/107 (39%), Gaps = 25/107 (23%)
Query: 1829 PGAPERHS---PIQNLD-------PPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLG 1878
P P +HS + NLD PP P +PPP+P + S A SP PL
Sbjct: 4886 PEPPTQHSYTYNVSNLDVRQLSAPPPEEP----SPPPSPLAPSPA-------SPPTEPLV 4934
Query: 1879 GVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPP 1925
+ PL P PS L P P+ P R+R P PP
Sbjct: 4935 ELPTEPLAEPPVPSPL----PLASSPESARPKPRARPPEEGEDSRPP 4977
Score = 35.4 bits (80), Expect = 0.77
Identities = 57/234 (24%), Positives = 88/234 (37%), Gaps = 32/234 (13%)
Query: 626 PPPPAPSPPPAPATSSRRPLLLRA-PQFTPSEAHLKIYESVLTPPPLGAPEA-PEPEPPP 683
P P P P PA + P L P+ P K+ E P P A P+ EP P
Sbjct: 3091 PGPLGPEERPPPAADASEPRLASVLPEVKP-----KVEEGGRHPSPCQFTIATPKVEPAP 3145
Query: 684 ADDSPA---EPEPRAVG-RTNHLSLPRFAPVVTTPVKAEVSPHGAPA---LSNGPQTQAQ 736
A +S +P +G R + F+ T KA G P L+ P +
Sbjct: 3146 AANSLGLGLKPGQSMMGSRDTRMGTGPFSSSGHTAEKASFGATGGPPAHLLTPSPLSGPG 3205
Query: 737 LLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGVGSLPLSGV---EEKMF 793
L+ + + LP P S ++ +E + +A L + + E+K
Sbjct: 3206 GSSLLEKFELESGALTLPGG-----PAASGDELDKMESSLVASELPLLIEDLLEHEKKEL 3260
Query: 794 SLLKRAKVQLFKIDQQQQQKVAASMPLSPG----------GQMEEVAGAVKQIS 837
++ QL QQQQQ+ S+ +PG G +AG+ +Q+S
Sbjct: 3261 QKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQLS 3314
Score = 34.3 bits (77), Expect = 1.7
Identities = 80/366 (21%), Positives = 115/366 (31%), Gaps = 61/366 (16%)
Query: 2086 SGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANG 2145
S PG + +L ++ + SE + + GGP G P + P +
Sbjct: 4010 SSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSL 4069
Query: 2146 SQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLG-----QV 2200
S SQ L P P L L P P ++ L++ G Q+
Sbjct: 4070 SGDSQLLLVQPQPQ----------PQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQL 4119
Query: 2201 FVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPL 2260
+ E VP + QP + P + T L P + P+ P PP P P
Sbjct: 4120 GSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGP-- 4177
Query: 2261 TLVLSSGPASP-------------PRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEAS 2307
VL SG P Q + K SP +A + + S
Sbjct: 4178 --VLQSGQGLPGVGIMPTVGQLRAQLQGVLAKN-PQLRHLSPQQQQQLQALLMQRQLQQS 4234
Query: 2308 EDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDR-----PGEPAG---EESPGPLQERSPLL 2359
+ Q P G +T ++G+L PG G E GP + P L
Sbjct: 4235 QAVRQTPPYQEPG-----TQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRL 4289
Query: 2360 PLPEDG-----------PPQVPDGPPDLLLESQWHHYSGEASSSEEEPPSPDDKENQAPK 2408
P P P P P + SQ S + + + PP+ PK
Sbjct: 4290 PAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPT----HPGTPK 4345
Query: 2409 RTGPHL 2414
GP L
Sbjct: 4346 PQGPTL 4351
Score = 32.3 bits (72), Expect = 6.5
Identities = 46/174 (26%), Positives = 69/174 (39%), Gaps = 26/174 (14%)
Query: 667 TPPPLGAPEAPEPEPPPADDSP---AEPEPRAVGRTNHLSLPRFAP-----VVTTPVKAE 718
T P A E E +P + DS +P+P+ + L P P V+ A
Sbjct: 4053 TTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAG 4112
Query: 719 VSPHGAPALSNGPQTQAQ-----LLQPLQALQTQ---LLPQALPPPQPQLQPP------P 764
HG L +G ++A L QP +L Q + L P QP L+ P P
Sbjct: 4113 GGSHGQ--LGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGP 4170
Query: 765 SPQQMPPLEKAR--IAGVGSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAA 816
P + P+ ++ + GVG +P G + QL + QQQQ++ A
Sbjct: 4171 QPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQA 4224
Score = 32.0 bits (71), Expect = 8.5
Identities = 37/149 (24%), Positives = 49/149 (32%), Gaps = 6/149 (4%)
Query: 375 DKEGEEKEERAVAEEMMPAAEKEEAKLPPPPL---TPPAPSPPPPLPPPSTSPPPPLCPP 431
D E + +++ + E + E K L P P P PPP+ P
Sbjct: 3054 DPELDTGDKKDIFNEHLRLVESANEKAEREALLRGVEPGPLGPEERPPPAADASEPRLAS 3113
Query: 432 PPPPVSPP-PLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPE 490
P V P P P Q PA S G P + GP
Sbjct: 3114 VLPEVKPKVEEGGRHPSPCQFTIATPKVEPAPAANSLGLGLKPGQSMMGSRDTRMGTGPF 3173
Query: 491 GTSPPTPTPST--ATGGPPEDSPTVAPKS 517
+S T ++ ATGGPP T +P S
Sbjct: 3174 SSSGHTAEKASFGATGGPPAHLLTPSPLS 3202
Score = 32.0 bits (71), Expect = 8.5
Identities = 24/78 (30%), Positives = 33/78 (42%), Gaps = 5/78 (6%)
Query: 545 RFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEP-APVPSPPRAPTPPSTPVPLPEKRRSI 603
R + PP+ P SP+ P SPP EP +P+ P A P +P+PL S
Sbjct: 4904 RQLSAPPPEEPSPPPSPLAPSP--ASPPT--EPLVELPTEPLAEPPVPSPLPLASSPESA 4959
Query: 604 LREPTFRWTSLTRELPPP 621
+P R + PP
Sbjct: 4960 RPKPRARPPEEGEDSRPP 4977
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 178 bits (452), Expect = 6e-44
Identities = 247/855 (28%), Positives = 326/855 (38%), Gaps = 217/855 (25%)
Query: 2001 EPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQ 2060
E +EE+VA +M S+ GP D ++ G + PGAP ++
Sbjct: 1146 EEEEEEMVAEESMASA--GPEDFEQD-------------------GEEAALAPGAPAVDS 1184
Query: 2061 LDGVDDGTDSEAEAV------------------QQPRGQGTPPSGPGVVRAGVLGAAGD- 2101
L G+++ D E EAV ++P PP PG+ + G + + +
Sbjct: 1185 L-GMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEP 1243
Query: 2102 -----RARPP---EDLPSEIVD-------FVLKNLGGPGDGGAGPREESLPPAPPLANGS 2146
ARPP E P ++ + L P PR S PP P + S
Sbjct: 1244 PAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDAS 1303
Query: 2147 QPS--------------QGLTASPA--DPTRTFAWLPGAP-----GVRVLSLGPAPEP-- 2183
PS GL S A T T PG G LSL P
Sbjct: 1304 HPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGS 1363
Query: 2184 ------PKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQP-PLP---------PTISPT 2227
P P+ S L G+ F EP P + PLP P SP
Sbjct: 1364 PFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPV 1423
Query: 2228 A-PTSWTLP---PGPLLGVLP-VVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKRV- 2281
T LP P PL LP V+ AP P PP L L+S P R+ R +R
Sbjct: 1424 LLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSP 1483
Query: 2282 -STFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRP 2340
S S P PP A L + PQ P S R TV LD
Sbjct: 1484 PSMLSLDGPLVRPPAGAA-LGRELLLLPGQPQTPVFPSTHDPR------TV--TLDFRNA 1534
Query: 2341 GEPAGEESPGPLQERSPLLPLPEDGPPQVPDGPPDLLLESQWHHYSGEASSSEEEPPSPD 2400
G PA P PL + P P P PP P P L++QW SE PP P
Sbjct: 1535 GIPA---PPPPLPPQPPPPPPP---PPVEPTKLPFKELDNQW--------PSEAIPPGPR 1580
Query: 2401 DKE-----------NQAPKRTGPHLRFEISSEDGFSVEAESLEGAWRTLIEKVQEA---- 2445
++ ++ P R P R E S E + +R E +
Sbjct: 1581 GRDEVTEEYMELAKSRGPWRRPPKKRHEDLVPPAGSPELSPPQPLFRPRSEFEEMTILYD 1640
Query: 2446 --RGHARLRHLSFSGMSGARLLG-------------IHHDAVIF-----------LAEQL 2479
G + F ++ RLL ++H + + E +
Sbjct: 1641 IWNGGIDEEDIRFLCVTYERLLQQDNGMDWLNDTLWVYHPSTSLSSAKKKKRDDGIREHV 1700
Query: 2480 PGAQRCQHY-------KFRYHQQGEGQ-EEPPLN---------PHGAARAEVYLRKCTFD 2522
G R + + K RY +EPP + PH + RA R
Sbjct: 1701 TGCARSEGFYTIDKKDKLRYLNSSRASTDEPPADTQGMSIPAQPHASTRAGSERR----- 1755
Query: 2523 MFNFLASQHRVLPE-GATCDEEEDEVQLRSTRRATSLELPMAMRFRHLKKTSKEAVGVYR 2581
+ Q R+L +CD + ++F LK K+ + +
Sbjct: 1756 -----SEQRRLLSSFTGSCDSD-------------------LLKFNQLKFRKKK-LKFCK 1790
Query: 2582 SAIHGRGLFCKRNIDAGEMVIEYSGIVIRSVLTDKREKFYDGKGIGC-YMFRMDDFDVVD 2640
S IH GLF I A EMVIEY G IR V+ D REK Y+ +GIG YMFR+D ++D
Sbjct: 1791 SHIHDWGLFAMEPIAADEMVIEYVGQNIRQVIADMREKRYEDEGIGSSYMFRVDHDTIID 1850
Query: 2641 ATMHGNAARFINHSCEPNCFSRVIHVEGQKHIVIFALRRILRGEELTYDYKFPIEDASNK 2700
AT GN ARFINHSC PNC+++VI VE QK IVI++ + I EE+TYDYKFPIED K
Sbjct: 1851 ATKCGNFARFINHSCNPNCYAKVITVESQKKIVIYSKQHINVNEEITYDYKFPIEDV--K 1908
Query: 2701 LPCNCGAKRCRRFLN 2715
+PC CG++ CR LN
Sbjct: 1909 IPCLCGSENCRGTLN 1923
Score = 94.7 bits (234), Expect = 1e-18
Identities = 115/426 (26%), Positives = 150/426 (35%), Gaps = 128/426 (30%)
Query: 366 EEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPA------PSPP----- 414
EE + E +E +E A+ P A++ EA+ P P P P PP
Sbjct: 1217 EEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPL 1276
Query: 415 ---PPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATC-----S 466
PPLPPP PP P PPP P + PS PP P E+ PP P C S
Sbjct: 1277 PLQPPLPPPR--PPRPPSPPPEPETTDASHPSVPPEPLAEDH----PPHTPGLCGSLAKS 1330
Query: 467 RKRGRPPLTPSQRAEREAARAGPEGTSP---------PTPTPSTATGGPPEDSPTVAPKS 517
+ P TP +G +SP P P+PS ++GG P +
Sbjct: 1331 QSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFT 1390
Query: 518 TTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVP--- 574
TF + ++PV + T RR P P V + L P+ P+P
Sbjct: 1391 PTFSEPSGPLLLPVCP------LPTGRRDERSGPLASP-VLLETGLPLPLPLPLPLPLAL 1443
Query: 575 ------QEPAPVPSPPRAPTP-PSTPVPLPEK----RRS----------ILREPTFRWTS 613
Q AP P PP P P S P P+ K RRS ++R P +
Sbjct: 1444 PAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPA--GAA 1501
Query: 614 LTREL------------------------------PPPPPAPPPPPAPSPPPAPATSSRR 643
L REL P PPP PP P P PPP P ++
Sbjct: 1502 LGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKL 1561
Query: 644 PLLLRAPQFTPSEA----------------------------HLKIYESVLTPPPLGAPE 675
P Q+ PSEA K +E ++ PP G+PE
Sbjct: 1562 PFKELDNQW-PSEAIPPGPRGRDEVTEEYMELAKSRGPWRRPPKKRHEDLV--PPAGSPE 1618
Query: 676 APEPEP 681
P+P
Sbjct: 1619 LSPPQP 1624
Score = 83.2 bits (204), Expect = 3e-15
Identities = 121/464 (26%), Positives = 163/464 (35%), Gaps = 77/464 (16%)
Query: 356 KQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPP 415
++++ ++EEE ++EEEE+D + ++ ++R +E + E+ L S
Sbjct: 1043 EEQESTEEEEEAEEEEEEEDDDDDDSDDRDESEN-----DDEDTALSEASEKDEGDSDEE 1097
Query: 416 PLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLT 475
TS S S P + E++EE +R+
Sbjct: 1098 ETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEE--------VVAREEEEEEEE 1149
Query: 476 PSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSAR 535
AE A AGPE + A G P DS + + V
Sbjct: 1150 EEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEE---------------VDIE 1194
Query: 536 SSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPV--PSPPRAPT---PP 590
+ V R M ++PP P VE R P P + QE A + P PP PP
Sbjct: 1195 TEAVAPEERPSMLDEPPLPVGVEEPADSREP-PEEPGLSQEGAMLLSPEPPAKEVEARPP 1253
Query: 591 STPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSR-------R 643
+P PE + EP L L PP P P PP PSPPP P T+
Sbjct: 1254 LSPERAPEHDLEVEPEPPM---MLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPE 1310
Query: 644 PLLLRAPQFTP----SEAHLKIYESV-LTP---PPLG------------APEAPEPEPPP 683
PL P TP S A + E+V TP PPL P +P P P
Sbjct: 1311 PLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAP 1370
Query: 684 ADDSPAEPEPRAVGRT-------NHLSLPRFAPVVTTPVKAEVSPHGAPA----LSNGPQ 732
+ + PR GR + S P PV P G A L G
Sbjct: 1371 SPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLP 1430
Query: 733 TQAQLLQPLQ-ALQTQLLPQA-LPPPQPQLQPPPSPQQMPPLEK 774
L PL AL L QA P P P L P P PP+++
Sbjct: 1431 LPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKR 1474
Score = 75.9 bits (185), Expect = 5e-13
Identities = 34/63 (53%), Positives = 37/63 (58%), Gaps = 1/63 (1%)
Query: 401 LPPPPLTPPAPSPPPPLPP-PSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPP 459
LPPPP PP P PPPP PP P PPPL PPPPPP P + PPPP PPP
Sbjct: 681 LPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPP 740
Query: 460 VVP 462
++P
Sbjct: 741 ILP 743
Score = 75.5 bits (184), Expect = 7e-13
Identities = 131/525 (24%), Positives = 178/525 (33%), Gaps = 102/525 (19%)
Query: 1886 PSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPL----------APRPPPSRWASPPLKT 1935
P+PG S+ + + V FP PP + AP PPP A P K
Sbjct: 389 PAPGFKSAFSPYQTPVAH--FPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKE 446
Query: 1936 SPQLRVPPPTSVVTALT----PTSGELAPPGPAPSPPPPED--LGPDFEDMEVVSGLSAA 1989
P PP ++ PT G P +P P E GP+ + S +
Sbjct: 447 KPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEML 506
Query: 1990 DLDFAASLLGT-EPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLA 2048
+ LL EP + + G P SS + SP + P S PG
Sbjct: 507 LKEQRTKLLFLREPDSDTEL------QMEGSPISSSSSQLSPLA-----PFGTNSQPGFR 555
Query: 2049 ----PSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRAR 2104
PS+ P + +E + E E + G PP AG+L + A
Sbjct: 556 GPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVAL 615
Query: 2105 PPEDLPSEIVDFVLKNLGGPGDGGAGPR--EESLPPAP------PLANGSQPSQGLTASP 2156
DL + K G G ++ +P AP P P A+P
Sbjct: 616 ---DLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAP 672
Query: 2157 ADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVK 2216
+ T LP PG L P P PP+P G P+PPP+
Sbjct: 673 SVLAPTLP-LPPPPGFPPLPPPPPPPPPQP---------------------GFPMPPPLP 710
Query: 2217 QPPLPPTISPTAPTSWTLPPGPLLGV--LPVVGVVRPAPPPPP---PPLTLVLS------ 2265
PP PP P A + T+PP PL +P ++ P PP PP P + + +S
Sbjct: 711 PPPPPP---PPAHPAVTVPPPPLPAPPGVPPPPILPPLPPFPPGLFPVMQVDMSHVLGGQ 767
Query: 2266 --SGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSR 2323
P S Q + R+ T G P PP+ A S G
Sbjct: 768 WGGMPMSFQMQTQVLSRLMTGQGACP--YPPFMA--------------AAAAAASAGLQF 811
Query: 2324 VRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLPLPEDGPPQ 2368
V + P RG L G G+ P PL + P +P P P Q
Sbjct: 812 VNL--PPYRGPFSLSNSGPGRGQHWP-PLPKFDPSVPPPGYMPRQ 853
Score = 73.2 bits (178), Expect = 3e-12
Identities = 45/113 (39%), Positives = 57/113 (50%), Gaps = 16/113 (14%)
Query: 367 EKKEEEEKDKEGEEK--EERAVAEEMMPAAEKEEAKLPPPPLTPP------APS---PPP 415
++ EK EG++ E+ ++++ MP+A A P P + P APS P
Sbjct: 620 DRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTL 679
Query: 416 PLPPPSTSPPPPLCPPPPPPVS----PPPLPS-PPPPPAQEEQEESPPPVVPA 463
PLPPP PP P PPPPPP PPPLP PPPPP PPP +PA
Sbjct: 680 PLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPA 732
Score = 67.0 bits (162), Expect = 2e-10
Identities = 103/408 (25%), Positives = 137/408 (33%), Gaps = 87/408 (21%)
Query: 399 AKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPL--------------PSP 444
A PPP PAP P T P+ PPPP P P+P
Sbjct: 379 AHTPPPAQATPAPGFKSAFSPYQT----PVAHFPPPPEEPTATAAFGARDSGEFRRAPAP 434
Query: 445 PP-PPAQEEQEESP--PPVVPATCSRKRGRPPLTPSQR-AEREAARAGPEGT-SPPTPTP 499
PP PPA+ +E P PP P PP T S R PE SP TPT
Sbjct: 435 PPLPPAEPLAKEKPGTPPGPP---------PPDTNSMELGGRPTFGWSPEPCDSPGTPTL 485
Query: 500 STATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEV 559
++ GP + ++ + LK R ++ + S ++ M+ P ++
Sbjct: 486 ESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQ-----MEGSPISSSSSQL 540
Query: 560 SPVLRPPITTSPPVPQEPAPVPSPPRAP-TPPSTPVPLPEKRRSILREPTFRWTSLTREL 618
SP L P T S P + P P S P + +P PLP+ L L
Sbjct: 541 SP-LAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDED---------EELDLGL 590
Query: 619 PPPPPAPPPPPAPS-------PPPAPATSSRRPLLLRAPQFTPSEAH-LKIYESVLTPPP 670
P PP P PP P+ R P + + S ++I + + P
Sbjct: 591 GPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAP 650
Query: 671 LGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNG 730
+ + + P+P P AV AP V P P G P L
Sbjct: 651 ITSADCPKP-------MVVTPGAAAVA----------APSVLAPTLPLPPPPGFPPLPPP 693
Query: 731 PQTQAQLLQPLQALQTQLLPQALPPPQPQLQP-------PPSPQQMPP 771
P P +P LPPP P P PP P PP
Sbjct: 694 PP-------PPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPP 734
Score = 65.5 bits (158), Expect = 7e-10
Identities = 131/538 (24%), Positives = 173/538 (32%), Gaps = 130/538 (24%)
Query: 404 PPLTPPAPSPPPPLPPPSTSP--------------PPPLCPPPPPPVSPPPLPSPPPPPA 449
P TP A PPPP P +T+ PPPL P P P P PPPP
Sbjct: 399 PYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPD 458
Query: 450 QEEQEESPPPVV---PATCSRKRGRPPLTPSQRAEREAARAGPEGT-------------- 492
E P P C G P L E++ AGPE
Sbjct: 459 TNSMELGGRPTFGWSPEPCDSP-GTPTL--------ESSPAGPEKPHDSLDSRIEMLLKE 509
Query: 493 ---------SPPTPTPSTATGGPPEDSPT----VAPKSTTFLKNIRQFIMPVVSARSSRV 539
P + T G P S + +AP T R P S SS
Sbjct: 510 QRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPGFRG-PTPPSSRPSSTG 568
Query: 540 IK--TPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQ-------EPAPVPSPPRAPTP- 589
++ +P D D + + + P RPP PP P E A R PT
Sbjct: 569 LEDISPTPLPDSDEDEELDLGLGP--RPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSE 626
Query: 590 --------------------PSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPP 629
PS P+ + + ++ P + L P P PPPP
Sbjct: 627 KMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPG 686
Query: 630 A-----PSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEP--P 682
P PPP P P L P P AH + + PPPL AP P P P
Sbjct: 687 FPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAV---TVPPPPLPAPPGVPPPPILP 743
Query: 683 PADDSPAEPEPRAVGRTNHL------SLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQ 736
P P P +H+ +P + T + ++ G A P A
Sbjct: 744 PLPPFPPGLFPVMQVDMSHVLGGQWGGMPMSFQMQTQVLSRLMTGQG--ACPYPPFMAAA 801
Query: 737 LLQPLQALQ-TQLLPQALP--------------PPQPQLQPP-PSPQQMPPLE---KARI 777
LQ L P P PP P+ P P P MP E KA +
Sbjct: 802 AAAASAGLQFVNLPPYRGPFSLSNSGPGRGQHWPPLPKFDPSVPPPGYMPRQEDPHKATV 861
Query: 778 AGVGSLPLSGVEEKMFSLLKRAKVQLFKI-------DQQQQQKVAASMPLSPGGQMEE 828
GV + L ++ M L R V++ D++++ A+ P+ G +E
Sbjct: 862 DGVLLVVLKELKAIMKRDLNRKMVEVVAFRAFDEWWDKKERMAKASLTPVKSGEHKDE 919
Score = 64.7 bits (156), Expect = 1e-09
Identities = 95/362 (26%), Positives = 108/362 (29%), Gaps = 142/362 (39%)
Query: 397 EEAKLPPPPLTPPA-------PSPPPPLPPPST-------------SPPPPLCPPPPPPV 436
E + P PP PPA P PP PPP T SP P P P
Sbjct: 427 EFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLE 486
Query: 437 SPPPLPSPP------------------------PPPAQEEQEESPP---------PVVP- 462
S P P P P E Q E P P+ P
Sbjct: 487 SSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPF 546
Query: 463 ATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPST----------ATGGPPEDSPT 512
T S+ R P PS R + G E SP TP P + PPE P
Sbjct: 547 GTNSQPGFRGPTPPSSRP----SSTGLEDISP-TPLPDSDEDEELDLGLGPRPPPEPGP- 600
Query: 513 VAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDE----------------------- 549
P L + + +V R+ K MDE
Sbjct: 601 --PDPAGLLSQTAEVALDLVGDRTPTSEK-----MDEGQQSSGEDMEISDDEMPSAPITS 653
Query: 550 -DPPKP------------PKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPL 596
D PKP P V + PP PP+P P P P P P PP P P
Sbjct: 654 ADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPP 713
Query: 597 PEKRRSILREPTFRWTSLTRELPPPPPAP----PPPPAPSPPPAPATSSRRPLLLRAPQF 652
P PPPP P PPPP P+PP P P+L P F
Sbjct: 714 P---------------------PPPPAHPAVTVPPPPLPAPPGVPPP----PILPPLPPF 748
Query: 653 TP 654
P
Sbjct: 749 PP 750
Score = 60.8 bits (146), Expect = 2e-08
Identities = 30/59 (50%), Positives = 32/59 (54%), Gaps = 4/59 (6%)
Query: 392 PAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPL--PSPPPPP 448
P + P PP PP P PPPP P T PPPPL P PP V PPP+ P PP PP
Sbjct: 694 PPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPL--PAPPGVPPPPILPPLPPFPP 750
Score = 52.0 bits (123), Expect = 8e-06
Identities = 23/40 (57%), Positives = 24/40 (60%), Gaps = 2/40 (5%)
Query: 402 PPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPL 441
PPPP P PPPPLP P PPPP+ PP PP PP L
Sbjct: 715 PPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPP--FPPGL 752
Score = 49.3 bits (116), Expect = 5e-05
Identities = 111/476 (23%), Positives = 149/476 (31%), Gaps = 95/476 (19%)
Query: 1785 PWGPREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPP 1844
P P + +E EE + AP P ++PPL V P + +PP
Sbjct: 1177 PGAPAVDSLGME--EEVDIETEAVAPEERPSMLDEPPLPVGV--------EEPADSREPP 1226
Query: 1845 LRPDSGSA-----PPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIP 1899
P P P AR P SP R P + P P P L +P
Sbjct: 1227 EEPGLSQEGAMLLSPEPPAKEVEAR---PPLSPERAPEHDLEVEPEPPMMLPLPLQPPLP 1283
Query: 1900 TVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTS---VVTALTPTSG 1956
PPR R PSP P P + + P + P PP + + S
Sbjct: 1284 ---------PPRPPRPPSP-PPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQST 1333
Query: 1957 ELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSS 2016
E P P PP +SG ++ L ++ + PF S
Sbjct: 1334 ETVPATPGGEPP--------------LSG-GSSGLSLSSPQVPGSPF------------S 1366
Query: 2017 HGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQ 2076
+ P S P + F T + P P P D+ + A V
Sbjct: 1367 YPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPL--PTGRRDERSGPLASPVL 1424
Query: 2077 QPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESL 2136
G P P + + +AR P LP ++ L + P G R
Sbjct: 1425 LETGLPLPLPLPLPLPLALPAVLRAQARAPTPLP-PLLPAPLASCPPPMKRKPG-RPRRS 1482
Query: 2137 PPAPPLANGSQPSQGLTASPADPT--RTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILV 2194
PP+ +G L PA R LPG P V P+ P+ T
Sbjct: 1483 PPSMLSLDGP-----LVRPPAGAALGRELLLLPGQPQTPVF---PSTHDPRTVT------ 1528
Query: 2195 NKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPT------------SWTLPPGP 2238
+ + AG P PP QPP PP P PT S +PPGP
Sbjct: 1529 -----LDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGP 1579
Score = 48.9 bits (115), Expect = 7e-05
Identities = 122/490 (24%), Positives = 155/490 (31%), Gaps = 102/490 (20%)
Query: 1796 EAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHS---------PIQNLDPPLR 1846
E EE + +V + +S P + + L PGAP S + + P R
Sbjct: 1144 EEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEER 1203
Query: 1847 PDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPS--------PGSPSSLTHHI 1898
P PP A + P P G + P P P SP H
Sbjct: 1204 PSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHD 1263
Query: 1899 PTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGEL 1958
V P PP P PL P PP R PP SP PP A P+
Sbjct: 1264 LEVE----PEPPMML--PLPLQPPLPPPR---PPRPPSP----PPEPETTDASHPS---- 1306
Query: 1959 APPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHG 2018
PP P PP G SL ++ E V A G
Sbjct: 1307 VPPEPLAEDHPPHTPG------------------LCGSLAKSQ--STETVPATPGGEPPL 1346
Query: 2019 GPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGA-PRIEQLDGVDDGTDSEAEA--- 2074
G S SSP P + S P +PS + G PR D T SE
Sbjct: 1347 SGGSSGLSLSSP-----QVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLL 1401
Query: 2075 ---VQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEI-VDFVLKNLGGPGDGGAG 2130
P G+ SGP + + VL G P LP + + VL+
Sbjct: 1402 LPVCPLPTGRRDERSGP--LASPVLLETGLPLPLPLPLPLPLALPAVLR--------AQA 1451
Query: 2131 PREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSK 2190
LPP P S P + P P R+ P + L GP PP A
Sbjct: 1452 RAPTPLPPLLPAPLASCPPP-MKRKPGRPRRS------PPSMLSLD-GPLVRPPAGAA-- 1501
Query: 2191 IILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVR 2250
LG+ + + G+ + P P T+ PP PL +
Sbjct: 1502 ------LGRELLLLPGQPQTPVFPSTHDPRTVTLD-FRNAGIPAPPPPL--------PPQ 1546
Query: 2251 PAPPPPPPPL 2260
P PPPPPPP+
Sbjct: 1547 PPPPPPPPPV 1556
Score = 46.6 bits (109), Expect = 3e-04
Identities = 52/210 (24%), Positives = 75/210 (35%), Gaps = 29/210 (13%)
Query: 1785 PWGPREEPAHL----EAAEENQTIVHSPAPSSEPPGGEDPPLDTDV-----LVPGAPERH 1835
P+G +P ++ + T + +P+ P ED LD + PG P+
Sbjct: 545 PFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPA 604
Query: 1836 SPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPNY--SPSRRPLGGVSFGPLPSPG--SP 1891
+ G P + + G + + S P ++ P P +P
Sbjct: 605 GLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTP 664
Query: 1892 SSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWA---SPPLKTSPQLRVPPPTSVV 1948
+ P+V P P PP P P P PPP + PPL P PPP
Sbjct: 665 GAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPP----PPPPPAH 720
Query: 1949 TALTPTSGELAPPGPAPSP---PPPEDLGP 1975
A+T PP P P+P PPP L P
Sbjct: 721 PAVT------VPPPPLPAPPGVPPPPILPP 744
Score = 44.7 bits (104), Expect = 0.001
Identities = 86/366 (23%), Positives = 117/366 (31%), Gaps = 81/366 (22%)
Query: 2069 DSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGG 2128
DS A P Q TP G + PPE+ P+ F G D G
Sbjct: 374 DSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEE-PTATAAF------GARDSG 426
Query: 2129 AGPREESLPPAPPLANGSQPSQGLTASPADPTR---------TFAWLP---GAPGVRVLS 2176
R + PP PP ++ G P P TF W P +PG L
Sbjct: 427 EFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLE 486
Query: 2177 LGPA-PEPP------------KPATSKIILVNKL---------GQVFVKMAGEGEPVPP- 2213
PA PE P K +K++ + + G + + P+ P
Sbjct: 487 SSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPF 546
Query: 2214 -----PVKQPPLPPTISPTAPTSWTLPPGPL----------LGVLPVVGVVRPAPPPPPP 2258
P + P PP+ P++ + P PL LG+ P RP P P PP
Sbjct: 547 GTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGP-----RPPPEPGPP 601
Query: 2259 PLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLD-EDGEASEDTPQVPGLG 2317
PA Q V + R+P + + + ED E S+D +
Sbjct: 602 D--------PAGLLSQTAEVA-LDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPIT 652
Query: 2318 SGGFSRVRMKTPTVRGV---------LDLDRPGEPAGEESPGPLQERSPLLPLPEDGPPQ 2368
S + + TP V L L P P P P P+P PP
Sbjct: 653 SADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPP 712
Query: 2369 VPDGPP 2374
P PP
Sbjct: 713 PPPPPP 718
Score = 42.4 bits (98), Expect = 0.006
Identities = 87/389 (22%), Positives = 124/389 (31%), Gaps = 76/389 (19%)
Query: 2011 GAMGSSHG--GPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGT 2068
GA+G + G GP ++ + S T + P APG + +P +
Sbjct: 355 GAVGGTGGSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFP------ 408
Query: 2069 DSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGG 2128
PP P A +G+ R P P + + K G G
Sbjct: 409 --------------PPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPG- 453
Query: 2129 AGPREESLPPAPPLAN----GSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPP 2184
P PP N G +P+ G + P D PG P + GP +P
Sbjct: 454 ---------PPPPDTNSMELGGRPTFGWSPEPCDS-------PGTPTLESSPAGP-EKPH 496
Query: 2185 KPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLP 2244
S+I ++ K + + E P L SP + +S L P G
Sbjct: 497 DSLDSRIEMLLKEQRTKLLFLRE------PDSDTELQMEGSPISSSSSQLSPLAPFGTNS 550
Query: 2245 VVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAP-PPYKAPRLDED 2303
G P PP P T + P P + R PP P PP A L +
Sbjct: 551 QPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQT 610
Query: 2304 GEASED-----TPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEP-AGEESPGPL----- 2352
E + D TP + G + + + D + P P + P P+
Sbjct: 611 AEVALDLVGDRTPTSEKMDEG-----QQSSGEDMEISDDEMPSAPITSADCPKPMVVTPG 665
Query: 2353 -------QERSPLLPLPEDGPPQVPDGPP 2374
+P LPLP PP P PP
Sbjct: 666 AAAVAAPSVLAPTLPLPP--PPGFPPLPP 692
Score = 39.7 bits (91), Expect = 0.041
Identities = 57/204 (27%), Positives = 68/204 (33%), Gaps = 49/204 (24%)
Query: 1791 EPAHL--EAAEENQTIVHSPAPSSEP------PGGEDPPLDTDVLVPGAPERHSPIQNLD 1842
+PA L + AE +V P+SE GED + D + P AP
Sbjct: 602 DPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEM-PSAPIT-------- 652
Query: 1843 PPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVG 1902
S P P + A + P+ PL P PG P P
Sbjct: 653 ------SADCPKPMVVTPGAAAVAAPSVLAPTLPLP-------PPPGFPPLPPPPPPPPP 699
Query: 1903 DPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPG 1962
P FP PP P P P PP P + VPPP L G PP
Sbjct: 700 QPGFPMPPPL---PPPPPPPPP----------AHPAVTVPPP-----PLPAPPGVPPPPI 741
Query: 1963 PAPSPPPPEDLGPDFE-DMEVVSG 1985
P PP P L P + DM V G
Sbjct: 742 LPPLPPFPPGLFPVMQVDMSHVLG 765
Score = 38.1 bits (87), Expect = 0.12
Identities = 16/30 (53%), Positives = 18/30 (60%)
Query: 401 LPPPPLTPPAPSPPPPLPPPSTSPPPPLCP 430
+PPPPL P PPPP+ PP PP L P
Sbjct: 725 VPPPPLPAPPGVPPPPILPPLPPFPPGLFP 754
Score = 34.3 bits (77), Expect = 1.7
Identities = 43/153 (28%), Positives = 55/153 (35%), Gaps = 23/153 (15%)
Query: 134 PSSLRSALRSQRGRAPRGRGRKHKTTPLPPPRLADVAPTPP---KTPARKRGEEGTERMV 190
P +L + LR+Q RAP TPLPP A +A PP + P R R M+
Sbjct: 1440 PLALPAVLRAQ-ARAP---------TPLPPLLPAPLASCPPPMKRKPGRPR--RSPPSML 1487
Query: 191 QALTELLRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIPKP 250
L+R R P P+ P + A + A P+P
Sbjct: 1488 SLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQP 1547
Query: 251 EPPPPVVPV-------KHQTGSWKCKEGPGPGP 276
PPPP PV K W + P PGP
Sbjct: 1548 PPPPPPPPVEPTKLPFKELDNQWPSEAIP-PGP 1579
Score = 32.3 bits (72), Expect = 6.5
Identities = 39/159 (24%), Positives = 54/159 (33%), Gaps = 23/159 (14%)
Query: 630 APSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPA 689
AP P + + + P E S+L PPL P PAD S
Sbjct: 1176 APGAPAVDSLGMEEEVDIETEAVAPEER-----PSMLDEPPL-----PVGVEEPAD-SRE 1224
Query: 690 EPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLL 749
PE + + + L P + +SP AP + + ++ PL
Sbjct: 1225 PPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLP------- 1277
Query: 750 PQALPPPQPQLQP--PPSPQQMPPLEKARIAGVGSLPLS 786
L PP P +P PPSP P A V PL+
Sbjct: 1278 ---LQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLA 1313
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 162 bits (410), Expect = 4e-39
Identities = 223/886 (25%), Positives = 309/886 (34%), Gaps = 160/886 (18%)
Query: 138 RSALRSQRGRAPR----GRGRKHKTTPLPPPRLADVAPTPPKTPARKRGEE-----GTER 188
RSA S R A R GRG + PP + + +P P +P R G G +
Sbjct: 81 RSAGTSSRNPASRPPASGRGER-----APPAK--NTSPGPVSSPGRASGTTRPGPLGQKG 133
Query: 189 MVQALTELLRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIP 248
+ + E + R +A +AP+ A R + G PG P+ R+ +A A V +P
Sbjct: 134 LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA---AGTEVGLP 190
Query: 249 KPEPP----PPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGGLPFV 304
+P P PP + S P P RR GGGL
Sbjct: 191 RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA-------------GGGLQ-- 235
Query: 305 IKFVSRAKKVKMGQLSLGLESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQE--QKLD 362
+ SR+ LS SG P R P K + Q L
Sbjct: 236 -RPASRSLSSSATPLSSPARSG-------------PSARGTPRAPAHPSQPKPKGLQALR 281
Query: 363 DEEEEKKEEEEKDKEGEEKEERAVAE-----EMMPAAEKEEAKLPPPPLTPPAP--SPPP 415
+ ++ G + P + A P P PP+P + P
Sbjct: 282 PPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPL 341
Query: 416 PLPPPSTSPPPPL----CPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGR 471
PL PPS S PP L PP PP PP + PP A + PP VP + + +
Sbjct: 342 PLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQ 401
Query: 472 PPLTPSQRAEREAARA---------------GPEGTSPPTPTPSTATGGPPEDSPTVAPK 516
P +P + +A + P T +PS PP+ P AP
Sbjct: 402 APPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPL 461
Query: 517 STTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTS-----P 571
S ++ + P VS SS + P + + P+ +S ++ PP+ T P
Sbjct: 462 SLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPP 521
Query: 572 PVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRW----TSLTRELPPPPPAPPP 627
+ PA + +PP P P PL + + L P + PP P PP
Sbjct: 522 SLQTPPASLTTPPLENLPSLAPPPL-QTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPP 580
Query: 628 PPAPS-----PPPAPATSSRRPLL-LRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEP 681
P PS PP AP + PL L +P +P L PPL AP +P P
Sbjct: 581 PETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASP 640
Query: 682 ---PPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNG-------- 730
P A SP P AV HL F+P + PV+A SP +P +S
Sbjct: 641 PLSPLATPSPQAPNALAV----HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP 696
Query: 731 PQTQAQLLQ--PLQALQTQLLPQALPPPQ-------PQLQPPPSPQQMPPLEKARI---- 777
P A LQ P + P A PPPQ P LQ PPSP PP+ +
Sbjct: 697 PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPR 756
Query: 778 -----------------AGVGSLPLSGVEEKMFSLLKRAKVQLF-----KIDQQQQQKVA 815
A + PL+ + L +Q Q +
Sbjct: 757 VPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS 816
Query: 816 ASMPLSPGGQMEEVAGAV--KQISDRGPVRSEDESVEAKRERPS-GPESPVQGPRIKHVC 872
AS+P+SP A V + P +++A R P+ GP++ V GPR
Sbjct: 817 ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPR----- 871
Query: 873 RHAAVALGQARAMVPEDVPRLSALPLRDRQDLATEDTSSASETESV 918
L A A P P S DLA +S+ S E +
Sbjct: 872 ------LTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEEL 911
Score = 105 bits (263), Expect = 5e-22
Identities = 107/378 (28%), Positives = 142/378 (37%), Gaps = 51/378 (13%)
Query: 392 PAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQE 451
P + +A PP P +PS PP P + PPL PP PP SPP PS PPP
Sbjct: 668 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 727
Query: 452 EQEESPPPVVPATCSRKRGRPPLTPSQRAEREA--ARAGPEGTSPPTPTPSTATGGPPED 509
+PP VP + PP++PS A P PP+P P++ P
Sbjct: 728 PPLAAPPLQVPPS---PPASPPMSPSATPPPRVPPLLAAPPLQVPPSP-PASLPMSPLAK 783
Query: 510 SPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITT 569
P AP + ++ P S +P + P P + PVL P+
Sbjct: 784 PPPQAPPALA-TPPLQALPSPPASFPGQAPF-SPSASLPMSPLATPPPQAPPVLAAPLLQ 841
Query: 570 SPPVPQEPAPVPSPPRAPTP-PSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPP 628
PP P + +P R PTP P T V P LT L P PPPP
Sbjct: 842 VPPSPPASPTLQAPRRPPTPGPDTSVSGPR---------------LTLAL---APGPPPP 883
Query: 629 PAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSP 688
P+ SP +T S L + T + L+ Y+S P GA +P PP A+ +
Sbjct: 884 PSRSP---SSTLSGPDLAGHSSSATSTPEELRGYDS---GPEGGAAASP---PPDAELAA 934
Query: 689 AEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQL 748
P + G L+ R AP P P A L +T+
Sbjct: 935 CHPAAWSRGPAPPLAF-RGAPGAPLPWPPATGPGSADGLCTIYETEG------------- 980
Query: 749 LPQALPPPQPQLQPPPSP 766
P++ P L P PSP
Sbjct: 981 -PESATPAPGALDPGPSP 997
Score = 101 bits (252), Expect = 9e-21
Identities = 175/703 (24%), Positives = 239/703 (33%), Gaps = 119/703 (16%)
Query: 1784 RPWGPREEPAH-LEAAEENQTIVHSPAPSSEPP--GGEDPPLDTDVLVPGAPERHSPIQN 1840
RP P E P + +A E+ T SPA P GG P + P SP ++
Sbjct: 197 RPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP-LSSPARS 255
Query: 1841 LDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRP----LGGVSFGPLPSPGSPSSLTH 1896
A P P+ ++ P +P R+ LG +S PL +P +
Sbjct: 256 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKAR 315
Query: 1897 HIPTVGDPDFPAPPRRSRRPSPLAPRP--PPSRWASPPLKTSPQLRVPPPTSVVTALTPT 1954
+P + P P P P P PPS A P L+T P PP+ ++T T
Sbjct: 316 PVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMT-T 374
Query: 1955 SGELAPPGPAPSPP--------------PPEDLGPDFEDMEVVSGLSAADLDFAASLLGT 2000
APP PP PP L ++ + L + L S L
Sbjct: 375 PPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLA--LSSLQATTSLGSPTLQATHSFLTM 432
Query: 2001 EPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATP-GAPR-- 2057
P Q + A +S P S+ +S P + P + L+P+ +P +P
Sbjct: 433 SPRQTQ-----ASLTSPSRPA-STPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTI 486
Query: 2058 --IEQLDGVDDGTDS-----------EAEAVQQPRGQGTPPSG---------PGVVRAGV 2095
++ L + + E ++ P TPP+ P + +
Sbjct: 487 HPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPL 546
Query: 2096 LGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESL---PPAPPLANGSQPSQGL 2152
A+ P + P L+ P S+ PP P A S P QGL
Sbjct: 547 QTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGL 606
Query: 2153 TASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKP---------ATSKIILVNKLGQVFVK 2203
+ P P T P L+L P PP P AT N L V +
Sbjct: 607 PSPPLSPLAT----PPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALA-VHLL 661
Query: 2204 MAGEGEPVPPPVK---QPPLPPTISPTAPTSWTLPPG---PLLGVLPVVGVVRP----AP 2253
A P PPV+ PP P +SP+A PP P L V P P A
Sbjct: 662 QAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 721
Query: 2254 PPP--PPPLTL----VLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEAS 2307
PPP PPPL V S PASPP +S + P PP AP L
Sbjct: 722 PPPQAPPPLAAPPLQVPPSPPASPP--------MSPSATPPPRVPPLLAAPPLQVPPSPP 773
Query: 2308 EDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLPLPEDGPP 2367
P P + + TP ++ + P PA P + L P PP
Sbjct: 774 ASLPMSPLAKPPPQAPPALATPPLQAL-----PSPPASFPGQAPFSPSASLPMSPLATPP 828
Query: 2368 QVPDGPPDLLLESQWHHYSGEASSSEEEPPSPDDKEN-QAPKR 2409
P PP L A+ + PPSP QAP+R
Sbjct: 829 --PQAPPVL------------AAPLLQVPPSPPASPTLQAPRR 857
Score = 80.1 bits (196), Expect = 3e-14
Identities = 77/274 (28%), Positives = 100/274 (36%), Gaps = 40/274 (14%)
Query: 392 PAAEKEEAKLPPPPLTPPAPSPPP---PLPPPSTSPPPPLCPPPP---PPVSPPPLPSPP 445
PA+ PPP PP + PP P PP++ P PL PPP P ++ PPL + P
Sbjct: 742 PASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALP 801
Query: 446 PPPAQEEQEE----------SP--------PPVVPATCSRKRGRPPLTPSQRAEREAARA 487
PPA + SP PPV+ A + PP +P+ +A R
Sbjct: 802 SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP 861
Query: 488 GPE-GTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRF 546
GP+ S P T + A G PP P+ +P ST P ++ SS TP
Sbjct: 862 GPDTSVSGPRLTLALAPGPPPP--PSRSPSST--------LSGPDLAGHSSSATSTPEEL 911
Query: 547 MDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILRE 606
D SP + P P P P P P+P P +
Sbjct: 912 RGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAP-PLAFRGAPGAPLPWPPATGPGSAD 970
Query: 607 PTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATS 640
E P A P P A P P+P TS
Sbjct: 971 GL----CTIYETEGPESATPAPGALDPGPSPGTS 1000
Score = 79.7 bits (195), Expect = 4e-14
Identities = 147/577 (25%), Positives = 194/577 (33%), Gaps = 99/577 (17%)
Query: 1831 APERHSPIQNLDPPLR-PDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPG 1889
+P R + PPL+ P S A PP S S P SP PL + PL +
Sbjct: 443 SPSRPASTPPDSPPLQAPLSLPASPPLQTSLS------PAVSPLSSPL---TIHPLQAL- 492
Query: 1890 SPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAP---RPPPSRWASPPLKTSPQLRVPPPTS 1946
SSL H P PP ++ S LAP + PP+ +PPL+ P L PPP
Sbjct: 493 --SSLASHSPQAPLSSLIMPPLETQ--SSLAPPSLQTPPASLTTPPLENLPSL-APPPLQ 547
Query: 1947 VVTALTPTSGELAPPGPAPSP---PPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPF 2003
+A T PP PAP P PP P E + A A L + P
Sbjct: 548 TASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSI----ATPPPQAPPALASPPL 603
Query: 2004 QEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDG 2063
Q G P ++P + P + P AP + P +P + L
Sbjct: 604 Q-------------GLPSPPLSPLATPPPQA---PPXLALPPLQAPPSPPASPPLSPL-A 646
Query: 2064 VDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAA---GDRARPPEDLPSEIVDFVLKN 2120
A AV + +PP P V A+ A PP P + L+
Sbjct: 647 TPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV 706
Query: 2121 LGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPA 2180
P + PP P + P Q + PA P + + P +L+ P
Sbjct: 707 PPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPL 766
Query: 2181 PEPPKPATSKIILVNKLGQVFVKMAGEGEPVP--------PPVKQPPLPPTISP-TAP-- 2229
PP P S + M+ +P P PP++ P PP P AP
Sbjct: 767 QVPPSPPAS------------LPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS 814
Query: 2230 TSWTLPPGPLLGVLPVVGVVRPAP------PPPPPPLTLVLSSGPASPPRQAIRVKRVST 2283
S +LP PL P V AP PP P P P ++ R++
Sbjct: 815 PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTL 874
Query: 2284 FSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEP 2343
PP PPP ++P G P + G S T T + D E
Sbjct: 875 ALAPGPP-PPPSRSPSSTLSG------PDLAGHSSSA-------TSTPEELRGYDSGPEG 920
Query: 2344 AGEESPGPLQE----------RSPLLPLPEDGPPQVP 2370
SP P E R P PL G P P
Sbjct: 921 GAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAP 957
Score = 77.4 bits (189), Expect = 2e-13
Identities = 127/517 (24%), Positives = 171/517 (33%), Gaps = 168/517 (32%)
Query: 395 EKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPL------------- 441
++++AK TP A +P +P PP P PPPPV+P L
Sbjct: 4 KRDKAKAGAAARTPAARAPG------LLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKP 57
Query: 442 -------------PSPPP------------------PPAQEEQEESPP-------PV--- 460
P P PPA E +PP PV
Sbjct: 58 LAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSP 117
Query: 461 ------------------VPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTP--- 499
+ A + RG+ P + A AR G +P TP+P
Sbjct: 118 GRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMA 177
Query: 500 --STATG---GPPEDSPTVAPKSTT----------------------------------- 519
S A G G P +P+ P+ T
Sbjct: 178 RRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRP 237
Query: 520 FLKNIRQFIMPVVS-ARSSRVIK-TPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEP 577
+++ P+ S ARS + TPR PKP ++ LRPP T P P
Sbjct: 238 ASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQ---ALRPPQVTPPRKDAAP 294
Query: 578 APVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPP----PPAPSP 633
A P + +P +TP P K R + P T L LPP PP P PP+PS
Sbjct: 295 A---LGPLSSSPLATPSPSGTKARPV-PPPDNAATPLPATLPPSPPLATPLPLAPPSPSA 350
Query: 634 PPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPP-------PADD 686
PP+ T L P PS+A +T PP+ AP + + PP +
Sbjct: 351 PPSLQT------LPSPPATPPSQA-----PPSMTTPPMQAPPSLQTIPPIQVPHSLTSPS 399
Query: 687 SPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQT 746
A P P A+ + + T +SP QTQA L P +
Sbjct: 400 LQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPR---------QTQASLTSPSR---- 446
Query: 747 QLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGVGSL 783
P + PP P LQ P S PPL+ + V L
Sbjct: 447 ---PASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPL 480
Score = 76.3 bits (186), Expect = 4e-13
Identities = 127/509 (24%), Positives = 169/509 (33%), Gaps = 93/509 (18%)
Query: 1820 PPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGG 1879
PPL+T + + P PPL APPP + A + P+ P
Sbjct: 510 PPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTA--SAPLTTPHLETPPCP--- 564
Query: 1880 VSFGPLPSPGSPSSLTHHIP----TVGDPDFPAPPRRSRRP---------SPLAPRPP-- 1924
P P PS LT P ++ P APP + P SPLA PP
Sbjct: 565 ---APCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQA 621
Query: 1925 PSRWASPPLKTSPQLRVPPPTSVVTALTPTSGEL-------APPGPAPSPPPPEDLGPDF 1977
P A PPL+ P PP S + +P + AP P PSPP P
Sbjct: 622 PPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 681
Query: 1978 EDMEVVSGL--SAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYI 2035
S S A AA L P A+ M S P + ++P +
Sbjct: 682 SPPVSPSATPPSQAPPSLAAPPLQVPPSPP---ASPPMSPSATPPPQAPPPLAAPP---L 735
Query: 2036 HFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGV 2095
P + ++P ++PSATP PR+ L + P Q PPS P +
Sbjct: 736 QVPPSPPASPPMSPSATP-PPRVPPL-------------LAAPPLQ-VPPSPPASLPMSP 780
Query: 2096 LGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPR----EESLPPAPPLANGSQPSQG 2151
L A+PP P + L+ L P G SLP +P Q
Sbjct: 781 L------AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV 834
Query: 2152 LTAS--------PADPTRTFAWLPGAPG----------VRVLSLGPAPEPPKPATSKIIL 2193
L A PA PT P PG L+ GP P P + +S +
Sbjct: 835 LAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSG 894
Query: 2194 VNKLGQVFVKMAGEGE-------PVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVV 2246
+ G + E P PP ++ P +W+ P P L
Sbjct: 895 PDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAP 954
Query: 2247 GVVRPAPPPPPPP-----LTLVLSSGPAS 2270
G P PP P T+ + GP S
Sbjct: 955 GAPLPWPPATGPGSADGLCTIYETEGPES 983
Score = 75.1 bits (183), Expect = 9e-13
Identities = 99/365 (27%), Positives = 140/365 (38%), Gaps = 64/365 (17%)
Query: 1809 APSSEPPGGEDPPLDTDVL-VPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKV 1867
+PS+ PP PPL L VP +P PP+ P S + PP P + ++V
Sbjct: 717 SPSATPPPQAPPPLAAPPLQVPPSPPA-------SPPMSP-SATPPPRVPPLLAAPPLQV 768
Query: 1868 PNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDP------DFPAPPRRSRRPSPLAP 1921
P P+ P+ ++ P +P P+ T + + P P P S SPLA
Sbjct: 769 PPSPPASLPMSPLAKPPPQAP--PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLAT 826
Query: 1922 RPPPSRWASPPLKTSPQLRVPP-----PTSVVTALTPTSG-ELAPPGP------APSPPP 1969
PP + PP+ +P L+VPP PT PT G + + GP AP PPP
Sbjct: 827 PPPQA----PPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 882
Query: 1970 PEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEES- 2028
P P S LS DL +S + P + +G G + P +E +
Sbjct: 883 PPSRSPS-------STLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAAC 935
Query: 2029 --SPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEA-EAVQQPRGQGTPP 2085
+ SR P+ APG AP P A DG+ ++E E+ G P
Sbjct: 936 HPAAWSRGPAPPLAFRGAPG-APLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPG 994
Query: 2086 SGPGVV--RAGVLGAAGDRARPPED----------LPSEIVDFVLKNL-------GGPGD 2126
PG +A AG +R P+ L + +V +L G G
Sbjct: 995 PSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGG 1054
Query: 2127 GGAGP 2131
G GP
Sbjct: 1055 SGGGP 1059
Score = 62.4 bits (150), Expect = 6e-09
Identities = 151/613 (24%), Positives = 207/613 (33%), Gaps = 139/613 (22%)
Query: 1850 GSAPPPAPRSFSGARIKVPNYSPSRRPL-------GGVSF-------GPLPSPGSPSSLT 1895
GS PP P + + R+ + R+PL GG + GP S G+ S
Sbjct: 31 GSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNP 90
Query: 1896 HHIPTVGDPDFPAPPRRSRRPSPLA--------PRPPP----------------SRWASP 1931
P APP ++ P P++ RP P +
Sbjct: 91 ASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEA 150
Query: 1932 PLKTSPQLRVPPPTSVVTALTPTSG----------ELAPPGPAPS--PPPPEDLGPDFED 1979
P +++ TS T TP+ E+ P PAPS P PP + GP
Sbjct: 151 PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE-GP---- 205
Query: 1980 MEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPV 2039
+ A+ TEP AA S+ GG P SR +
Sbjct: 206 --------RKSVSSASEHSTTEPSP----AARRRPSAGGG-------LQRPASRSLSSSA 246
Query: 2040 TVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEA---EAVQQPRGQGTPPSGP-GVVRAGV 2095
T +S+P + + G PR +A V PR P GP
Sbjct: 247 TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT 306
Query: 2096 LGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTAS 2155
+G +ARP P D A P +LPP+PPLA P S
Sbjct: 307 PSPSGTKARPVP----------------PPDNAATPLPATLPPSPPLAT---PLPLAPPS 347
Query: 2156 PADPTRTFAWLPGAPGVRVLSLGPA-PEPPKPATSKIILVNKLGQVFVKMAGEGEPVPP- 2213
P+ P + LP P P+ PP A + + + QV + PP
Sbjct: 348 PSAPP-SLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPI-QVPHSLTSPSLQAPPS 405
Query: 2214 PVKQPPLPPTISPTAPTSWT----LPPGPLLGVLPVVGVVRPA-PPPPPPPLTLVLSSGP 2268
P+ L T S +PT L P + RPA PP PPL LS P
Sbjct: 406 PLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSL-P 464
Query: 2269 ASPPRQAI---------------RVKRVSTFSGRSPPAP------PPYK-----APRLDE 2302
ASPP Q ++ +S+ + SP AP PP + AP +
Sbjct: 465 ASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQ 524
Query: 2303 DGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQ-ERSPLLPL 2361
AS TP + L S ++ + + L+ P PA P PLQ SPL
Sbjct: 525 TPPASLTTPPLENLPSLAPPPLQTASAPLT-TPHLETPPCPA----PCPLQAPPSPLTTP 579
Query: 2362 PEDGPPQVPDGPP 2374
P + P + PP
Sbjct: 580 PPETPSSIATPPP 592
Score = 48.1 bits (113), Expect = 1e-04
Identities = 95/343 (27%), Positives = 118/343 (34%), Gaps = 65/343 (18%)
Query: 2070 SEAEAVQQPRGQGTPPSGPGVVRAG--VLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDG 2127
+ A + PR G+P P V A VLGAAG R P + + GG G G
Sbjct: 19 ARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKP----------LAERAGGIG-G 67
Query: 2128 GAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPA 2187
P ES P A P + S+ + P R AP + S GP P +
Sbjct: 68 ATIP--ESAPRAGPTRSAGTSSRNPASRPPASGRG----ERAPPAKNTSPGPVSSPGR-- 119
Query: 2188 TSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTA--PTSWTLP--PGPLL--- 2240
S LGQ ++++ E + P +S A TS P P P +
Sbjct: 120 ASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARR 179
Query: 2241 --GVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAP 2298
VG+ RPAP P P P PR K VS+ S S P P
Sbjct: 180 SRAAGTEVGLPRPAPSARPRP--------PTEGPR-----KSVSSASEHSTTEPSPAARR 226
Query: 2299 RLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGP--LQERS 2356
R G Q P S S + +P G P PA P P LQ
Sbjct: 227 RPSAGGGL-----QRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALR 281
Query: 2357 PLLPLPEDGPPQVPDGPPDLLLESQWHHYSGEASSSEEEPPSP 2399
P P+ PP+ D P L G SSS PSP
Sbjct: 282 P----PQVTPPR-KDAAPAL----------GPLSSSPLATPSP 309
Score = 34.7 bits (78), Expect = 1.3
Identities = 31/109 (28%), Positives = 39/109 (35%), Gaps = 14/109 (12%)
Query: 1033 DESPEASPGPPGPRRGAGAGGPREEVVAHPGPEEQDSL---LQRKSARRCVKQRPSYDIF 1089
+ +P A PGP G R PGP Q L + AR + P
Sbjct: 101 ERAPPAKNTSPGPVSSPG----RASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSAL 156
Query: 1090 EDSDDSEPGGP----PAP---RRRTPRENELPLPEPEEQSRPRKPTLQP 1131
+ GP P+P RR E+ LP P +RPR PT P
Sbjct: 157 SAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGP 205
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 156 bits (394), Expect = 3e-37
Identities = 181/650 (27%), Positives = 245/650 (37%), Gaps = 135/650 (20%)
Query: 2179 PAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGP 2238
P E P P + + +V V G PV P +Q P P PT + P P
Sbjct: 1080 PPREVPVPTPAPV-------EVPVPERVAGSPVTPLPEQEASPAR--PAGPTEESPPSAP 1130
Query: 2239 LLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSG-RSPPAPPPY-- 2295
L P G PAP P P + + P R+ + + PPA PP
Sbjct: 1131 LRPPEPPAGPPAPAPRPDERPSSPIPLLPPPKKRRKTVSFSAIEVVPAPEPPPATPPQAK 1190
Query: 2296 -------KAPR----------LDED---------------------GEASEDTPQVPG-- 2315
KAPR LD G +E+ PG
Sbjct: 1191 FPGPASRKAPRGVERTIRNLPLDHASLVKSWPEEVSRGGRSRAGGRGRLTEEEEAEPGTE 1250
Query: 2316 -----LGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQER-----------SPLL 2359
L + R P + V D + E P PL P
Sbjct: 1251 VDLAVLADLALTPARRGLPALPAVEDSEATETSDEAERPRPLLSHILLEHNYALAVKPTP 1310
Query: 2360 PLPEDGPPQ-VP------DGPPDLLLESQWHHYSGEASSSEEEPPSPDDKENQAPK--RT 2410
P P PP+ VP P D +LE+ E +E E P P + Q +
Sbjct: 1311 PAPALRPPEPVPAPAALFSSPADEVLEAP------EVVVAEAEEPKPQQLQQQREEGEEE 1364
Query: 2411 GPHLRFEISSEDGFSVEAESLEGAWRTLIEKVQEARGHARLRH----------LSFSGMS 2460
G E E S + EGA R + R HAR R ++ S
Sbjct: 1365 GEEEGEEEEEESSDSSSSSDGEGALRR-----RSLRSHARRRRPPPPPPPPPPRAYEPRS 1419
Query: 2461 GARLLGIHHD----------------AVIFLAEQLPGAQRCQHYKFRYH---------QQ 2495
+ I +D L +Q GA + +H ++
Sbjct: 1420 EFEQMTILYDIWNSGLDSEDMSYLRLTYERLLQQTSGADWLNDTHWVHHTITNLTTPKRK 1479
Query: 2496 GEGQEEPPLNPHGAARAEVY--LRKCTFDMFNFLASQHRVLPEGA-------TCDEEEDE 2546
Q+ P + G+AR+E Y + K D + + EG E E
Sbjct: 1480 RRPQDGPREHQTGSARSEGYYPISKKEKDKYLDVCPVSARQLEGVDTQGTNRVLSERRSE 1539
Query: 2547 VQLRSTRRATSLELPMAMRFRHLKKTSKEAVGVYRSAIHGRGLFCKRNIDAGEMVIEYSG 2606
+ + TS + + + K K+ + RS IH GLF I A EMVIEY G
Sbjct: 1540 QRRLLSAIGTSAIMDSDLLKLNQLKFRKKKLRFGRSRIHEWGLFAMEPIAADEMVIEYVG 1599
Query: 2607 IVIRSVLTDKREKFYDGKGIGC-YMFRMDDFDVVDATMHGNAARFINHSCEPNCFSRVIH 2665
IR ++ D REK Y +GIG Y+FR+D ++DAT GN ARFINH C PNC+++VI
Sbjct: 1600 QNIRQMVADMREKRYVQEGIGSSYLFRVDHDTIIDATKCGNLARFINHCCTPNCYAKVIT 1659
Query: 2666 VEGQKHIVIFALRRILRGEELTYDYKFPIEDASNKLPCNCGAKRCRRFLN 2715
+E QK IVI++ + I EE+TYDYKFP+ED NK+PC CG + CR LN
Sbjct: 1660 IESQKKIVIYSKQPIGVDEEITYDYKFPLED--NKIPCLCGTESCRGSLN 1707
Score = 81.3 bits (199), Expect = 1e-14
Identities = 87/312 (27%), Positives = 117/312 (37%), Gaps = 51/312 (16%)
Query: 373 EKDKEGEEKEERAVAEEMMPAAEKEEAKLP---PPPLTPPAP-----SPPPPLPPPSTSP 424
E E EE+EER A +P+A ++P P P+ P P SP PLP SP
Sbjct: 1059 ESSSEDEEEEERPAA---LPSASPPPREVPVPTPAPVEVPVPERVAGSPVTPLPEQEASP 1115
Query: 425 PPPLCP----PPPPPVSPPPLPSPPPPPA--QEEQEESPPPVVPATCSRKRGRPPLTPSQ 478
P P PP P+ PP P+ PP PA +E+ SP P++P PP +
Sbjct: 1116 ARPAGPTEESPPSAPLRPPEPPAGPPAPAPRPDERPSSPIPLLP---------PPKKRRK 1166
Query: 479 RAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIM--------- 529
A P PP P GP + AP+ + IR +
Sbjct: 1167 TVSFSAIEVVPAPEPPPATPPQAKFPGP---ASRKAPRGVE--RTIRNLPLDHASLVKSW 1221
Query: 530 PVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPP---VPQEPAPVPSPPRA 586
P +R R R + E+ P EV + + +P +P PA V
Sbjct: 1222 PEEVSRGGRSRAGGRGRLTEEEEAEPGTEVDLAVLADLALTPARRGLPALPA-VEDSEAT 1280
Query: 587 PTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPP-PPPAPSPPPAPATSSRRPL 645
T P P +L + + P PPAP PP P P PA SS
Sbjct: 1281 ETSDEAERPRPLLSHILLEH------NYALAVKPTPPAPALRPPEPVPAPAALFSSPADE 1334
Query: 646 LLRAPQFTPSEA 657
+L AP+ +EA
Sbjct: 1335 VLEAPEVVVAEA 1346
Score = 68.9 bits (167), Expect = 6e-11
Identities = 89/361 (24%), Positives = 112/361 (31%), Gaps = 80/361 (22%)
Query: 128 SDEDVAPSSLRSALRSQRGRAP---RGRGRKHKTTPLPPPRLADVAPTPPKTPARKRGEE 184
S + SS S RS P R + T PP R P P E
Sbjct: 346 SSSSSSSSSSSSQFRSSDANYPAYYESWNRYQRHTSYPPRRATREEP-----PGAPFAEN 400
Query: 185 GTERMVQALTELLRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVVAEAA 244
ER + T L EPS P RPP A
Sbjct: 401 TAERFPPSYTSYLPP------------EPSRPTDQDYRPPASEA---------------- 432
Query: 245 VTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGR--GGGLP 302
P PEPP P G GP P R + + R G +P
Sbjct: 433 ---PPPEPPEP--------GGGGGGGGPSPEREEVRTSPRPASPARSGSPAPETTNESVP 481
Query: 303 FV--------IKFVSRAKKVKMGQLSLGLESGQGQGQHEESWQDVPQRRVGSGQGGSPCW 354
F I+ + + ++ K L+ E + +D V SG G PC
Sbjct: 482 FAQHSSLDSRIEMLLKEQRSKFSFLASDTEEEEENSSMVLGARDTGSE-VPSGSGHGPCT 540
Query: 355 KK------QEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTP 408
++ E E G+ + + + M ++ + PPP TP
Sbjct: 541 PPPAPANFEDVAPTGSGEPGATRESPKANGQNQASPCSSGDDMEISDDDRGGSPPPAPTP 600
Query: 409 PAPSPPPPLPPPSTSPPPPLC-------PPPPPPVSPPPLPSPPPPPAQEEQEESPPPVV 461
P PPPP PPP PPPP PP P PP P PPPP E PPP
Sbjct: 601 PQQPPPPPPPPP---PPPPYLASLPLGYPPHQPAYLLPPRPDGPPPP------EYPPPPP 651
Query: 462 P 462
P
Sbjct: 652 P 652
Score = 67.0 bits (162), Expect = 2e-10
Identities = 106/385 (27%), Positives = 139/385 (36%), Gaps = 73/385 (18%)
Query: 533 SARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPP-- 590
S+ SS + E + + E P P + SPP + P P P+P P P
Sbjct: 1043 SSSSSSSSSSSSSSSSESSSEDEEEEERPAALP--SASPPPREVPVPTPAPVEVPVPERV 1100
Query: 591 --STPVPLPEKRRSILREPTFRWTSLTRELPPP----PPAPPP-PPAPSPPPAPATSSRR 643
S PLPE+ S R T E PP PP PP PPAP+P P SS
Sbjct: 1101 AGSPVTPLPEQEASPARP-----AGPTEESPPSAPLRPPEPPAGPPAPAPRPDERPSSPI 1155
Query: 644 PLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPAD-DSPAEPE-PRAVGRT-N 700
PLL P + + S + P APE P PP A PA + PR V RT
Sbjct: 1156 PLLP-----PPKKRRKTVSFSAIEVVP--APEPPPATPPQAKFPGPASRKAPRGVERTIR 1208
Query: 701 HLSLPRFAPVVTTPVKAEVSPHG-APALSNGPQTQAQLLQPLQALQTQLLPQ-ALPP--- 755
+L L + V + P EVS G + A G T+ + +P + +L AL P
Sbjct: 1209 NLPLDHASLVKSWP--EEVSRGGRSRAGGRGRLTEEEEAEPGTEVDLAVLADLALTPARR 1266
Query: 756 ----------------------PQPQLQ--------------PPPSPQQMPPLEKARIAG 779
P+P L PP+P PP A
Sbjct: 1267 GLPALPAVEDSEATETSDEAERPRPLLSHILLEHNYALAVKPTPPAPALRPPEPVPAPAA 1326
Query: 780 VGSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISD- 838
+ S P V E ++ A+ K Q QQQ+ G+ EE + S
Sbjct: 1327 LFSSPADEVLEAPEVVVAEAEEP--KPQQLQQQREEGEEEGEEEGEEEEEESSDSSSSSD 1384
Query: 839 -RGPVRSEDESVEAKRERPSGPESP 862
G +R A+R RP P P
Sbjct: 1385 GEGALRRRSLRSHARRRRPPPPPPP 1409
Score = 65.5 bits (158), Expect = 7e-10
Identities = 83/305 (27%), Positives = 102/305 (33%), Gaps = 88/305 (28%)
Query: 384 RAVAEEM--MPAAEKEEAKLPPPPLT--PPAPSPPPPLP--PPSTSPPPPLCPPP----- 432
RA EE P AE + PP + PP PS P PP++ PPP P P
Sbjct: 386 RATREEPPGAPFAENTAERFPPSYTSYLPPEPSRPTDQDYRPPASEAPPPEPPEPGGGGG 445
Query: 433 --------------PPPVSPPPLPSPPPPPAQEE----QEESPPPVVPATCSRKRGRPPL 474
P P SP SP P E Q S + +R +
Sbjct: 446 GGGPSPEREEVRTSPRPASPARSGSPAPETTNESVPFAQHSSLDSRIEMLLKEQRSKFSF 505
Query: 475 TPSQRAERE--------AARAGPE-----GTSPPTPTPSTA-------TGGPPEDSPTVA 514
S E E A G E G P TP P+ A TG + +
Sbjct: 506 LASDTEEEEENSSMVLGARDTGSEVPSGSGHGPCTPPPAPANFEDVAPTGSGEPGATRES 565
Query: 515 PKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVP 574
PK+ N + P S + D+D P PP +P P
Sbjct: 566 PKA-----NGQNQASPCSSGDDMEI-------SDDDRGGSP---------PP---APTPP 601
Query: 575 QEPAPVPSPPRAPTP--PSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPS 632
Q+P P P PP P P S P+ P + + L LPP P PPPP P
Sbjct: 602 QQPPPPPPPPPPPPPYLASLPLGYPPHQPAYL-------------LPPRPDGPPPPEYPP 648
Query: 633 PPPAP 637
PPP P
Sbjct: 649 PPPPP 653
Score = 58.2 bits (139), Expect = 1e-07
Identities = 86/335 (25%), Positives = 104/335 (31%), Gaps = 95/335 (28%)
Query: 404 PPLTPPAPSPPPPLPPPSTS--PPPPLCPP-----PPPPVSPPPLPSPP--------PPP 448
PP P A + PP TS PP P P PP +PPP P P P P
Sbjct: 392 PPGAPFAENTAERFPPSYTSYLPPEPSRPTDQDYRPPASEAPPPEPPEPGGGGGGGGPSP 451
Query: 449 AQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPP- 507
+EE SP P P AR+G +P P T P
Sbjct: 452 EREEVRTSPRPASP----------------------ARSG-------SPAPETTNESVPF 482
Query: 508 EDSPTVAPKSTTFLKNIRQFIMPVVS------ARSSRVIKTPRRFMDEDPPKPPKVEVSP 561
++ + LK R + S SS V+ D P P
Sbjct: 483 AQHSSLDSRIEMLLKEQRSKFSFLASDTEEEEENSSMVLGA----RDTGSEVPSGSGHGP 538
Query: 562 VLRPPITTS-----PPVPQEPAPVPSPPRA-------PTPPSTPVPLPEKRRSILREPTF 609
PP + P EP P+A P + + + R P
Sbjct: 539 CTPPPAPANFEDVAPTGSGEPGATRESPKANGQNQASPCSSGDDMEISDDDRGGSPPPA- 597
Query: 610 RWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPP 669
P PP PPPPP P PPP P +S L L P P+ +L P
Sbjct: 598 ---------PTPPQQPPPPPPPPPPPPPYLAS---LPLGYPPHQPA--------YLLPPR 637
Query: 670 PLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSL 704
P G P P PPP P P N L L
Sbjct: 638 PDGPPPPEYPPPPP-------PPPHIYDFVNSLEL 665
Score = 50.4 bits (119), Expect = 2e-05
Identities = 65/247 (26%), Positives = 93/247 (37%), Gaps = 36/247 (14%)
Query: 1833 ERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLP----SP 1888
ER + + + PP P P PAP ++VP P R + G PLP SP
Sbjct: 1069 ERPAALPSASPP--PREVPVPTPAP-------VEVP--VPER--VAGSPVTPLPEQEASP 1115
Query: 1889 GSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVV 1948
P+ T P P PP P AP P P S P+ +PPP
Sbjct: 1116 ARPAGPTEESPPSAPLRPPEPPA-----GPPAPAPRPDERPSSPIP-----LLPPPKKRR 1165
Query: 1949 TALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAA----DLDFAASLLGTEPFQ 2004
++ ++ E+ P P PP+ P + G+ LD ASL+ + P
Sbjct: 1166 KTVSFSAIEVVPAPEPPPATPPQAKFPGPASRKAPRGVERTIRNLPLDH-ASLVKSWP-- 1222
Query: 2005 EEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGV 2064
EE+ G S GG G +EEE + + V A A P P +E +
Sbjct: 1223 EEVSRGGR--SRAGGRGRLTEEEEAEPGTEVDLAVLADLALTPARRGLPALPAVEDSEAT 1280
Query: 2065 DDGTDSE 2071
+ ++E
Sbjct: 1281 ETSDEAE 1287
Score = 48.9 bits (115), Expect = 7e-05
Identities = 94/419 (22%), Positives = 129/419 (30%), Gaps = 66/419 (15%)
Query: 114 SDGESDEEEFQGFHSDEDVAPSSLRSALRSQRGRAPRGRGRKHKTTPLP----PPRLADV 169
+D SD E S + SS S+ S + + + LP PPR V
Sbjct: 1027 NDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPREVPV 1086
Query: 170 ---APTPPKTPARKRGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPRRS----RGR 222
AP P R G T Q + ++P S P P R
Sbjct: 1087 PTPAPVEVPVPERVAGSPVTPLPEQEASPARPAGPTEESPPSAPLRPPEPPAGPPAPAPR 1146
Query: 223 PPGRPAGPCR-----RKQQAVVVAEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGPG 277
P RP+ P +K++ V A +P PEPPP P + PGP
Sbjct: 1147 PDERPSSPIPLLPPPKKRRKTVSFSAIEVVPAPEPPPATPP-----------QAKFPGPA 1195
Query: 278 TPRRGGQSSRGGRGGRGRGRGGGLPFVIKFVSRAKKVKMGQLSLGLESGQGQGQHEESWQ 337
S + RG R L S ++V G G G+G+ E +
Sbjct: 1196 -------SRKAPRGVERTIRNLPLDHASLVKSWPEEVSRG----GRSRAGGRGRLTEEEE 1244
Query: 338 DVPQRRVG----------SGQGGSPCWKKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVA 387
P V + G P E D E E +E E+ R +
Sbjct: 1245 AEPGTEVDLAVLADLALTPARRGLPALPAVE---DSEATETSDEAERP--------RPLL 1293
Query: 388 EEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPP-STSPPPPLCPPPPPPVSPPPLPSPPP 446
++ A P PP P P P P +SP + P V+ P P
Sbjct: 1294 SHILLEHNYALAVKPTPPAPALRPPEPVPAPAALFSSPADEVLEAPEVVVAEAEEPKPQQ 1353
Query: 447 PPAQEE------QEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTP 499
Q E +EE ++ S +R+ R AR PP P P
Sbjct: 1354 LQQQREEGEEEGEEEGEEEEEESSDSSSSSDGEGALRRRSLRSHARRRRPPPPPPPPPP 1412
Score = 45.8 bits (107), Expect = 6e-04
Identities = 87/375 (23%), Positives = 112/375 (29%), Gaps = 127/375 (33%)
Query: 1909 PPRRSRRPSPL-APRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGP-APS 1966
PPRR+ R P AP + PP TS +PP S PT + PP AP
Sbjct: 383 PPRRATREEPPGAPFAENTAERFPPSYTS---YLPPEPS-----RPTDQDYRPPASEAPP 434
Query: 1967 PPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEE 2026
P PPE G GG G S E
Sbjct: 435 PEPPEP-----------------------------------------GGGGGGGGPSPER 453
Query: 2027 ESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDD----------------GTDS 2070
E TS P + + AP T + Q +D +D+
Sbjct: 454 EEVRTSPR---PASPARSGSPAPETTNESVPFAQHSSLDSRIEMLLKEQRSKFSFLASDT 510
Query: 2071 EAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAG 2130
E E G +G + V +G P P+ D G PG
Sbjct: 511 EEEEENSSMVLGARDTG-----SEVPSGSGHGPCTPPPAPANFEDVAPTGSGEPGATRES 565
Query: 2131 PREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSK 2190
P+ A P ++G +D R G+P PAP PP+
Sbjct: 566 PKANGQNQASPCSSGDD------MEISDDDRG-----GSPP-------PAPTPPQ----- 602
Query: 2191 IILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTIS------PTAPTSWTLPPGPLLGVLP 2244
+P PPP PP PP ++ P ++ LPP P P
Sbjct: 603 ------------------QPPPPPPPPPPPPPYLASLPLGYPPHQPAYLLPPRPDGPPPP 644
Query: 2245 VVGVVRPAPPPPPPP 2259
PPPPPPP
Sbjct: 645 EY-----PPPPPPPP 654
Score = 44.3 bits (103), Expect = 0.002
Identities = 50/202 (24%), Positives = 69/202 (34%), Gaps = 21/202 (10%)
Query: 1853 PPPAPRSFSGARIK---VPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAP 1909
PPPAP +F P + G + S G ++ P P P
Sbjct: 541 PPPAPANFEDVAPTGSGEPGATRESPKANGQNQASPCSSGDDMEISDDDRGGSPPPAPTP 600
Query: 1910 PRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPP 1969
P++ P P P PPP AS PL PP L P PP P PPP
Sbjct: 601 PQQPPPPPP-PPPPPPPYLASLPLGY-------PPHQPAYLLPPRPDGPPPPEYPPPPPP 652
Query: 1970 PEDLGPDFEDMEVVSGLSA----ADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSE 2025
P + +E++ L A + F + G + +S G PG +
Sbjct: 653 PPHIYDFVNSLELMDRLGAQWGGMPMSFQMQTQMLTRLHQLRQGKGLIAASAGPPGGAFG 712
Query: 2026 EESSPTSRYIHFPVTVVSAPGL 2047
E ++ FP +A GL
Sbjct: 713 E------AFLPFPPPQEAAYGL 728
Score = 43.5 bits (101), Expect = 0.003
Identities = 72/271 (26%), Positives = 89/271 (32%), Gaps = 59/271 (21%)
Query: 543 PRRFMDEDPPKPPKVEVSPVLRPPITTS--PPVPQEP-----------APVPSPPRAPTP 589
PRR E+PP P E + PP TS PP P P AP P PP
Sbjct: 384 PRRATREEPPGAPFAENTAERFPPSYTSYLPPEPSRPTDQDYRPPASEAPPPEPPEPGGG 443
Query: 590 PSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAP-----SPPPAPATS--SR 642
P PE R + P P PA PAP S P A +S SR
Sbjct: 444 GGGGGPSPE-REEVRTSPR-----------PASPARSGSPAPETTNESVPFAQHSSLDSR 491
Query: 643 RPLLLRAPQ----FTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGR 698
+LL+ + F S+ + S + LGA + P + P P P
Sbjct: 492 IEMLLKEQRSKFSFLASDTEEEEENSSMV---LGARDTGSEVPSGSGHGPCTPPPAPA-- 546
Query: 699 TNHLSLPRFAPVVTT----PVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALP 754
F V T P SP P + ++ + P A
Sbjct: 547 -------NFEDVAPTGSGEPGATRESPKANGQNQASPCSSGDDMEISDDDRGGSPPPAPT 599
Query: 755 PPQPQLQPPPSPQQMPPLEKARIAGVGSLPL 785
PPQ PPP P PP + SLPL
Sbjct: 600 PPQQPPPPPPPPPPPPPY-------LASLPL 623
Score = 43.5 bits (101), Expect = 0.003
Identities = 83/362 (22%), Positives = 123/362 (33%), Gaps = 59/362 (16%)
Query: 1796 EAAEENQTIVHSPA--PSSEPPGGEDP---PLDTDVLVP----GAPERHSPIQNLDP--- 1843
E++ E++ PA PS+ PP E P P +V VP G+P P Q P
Sbjct: 1059 ESSSEDEEEEERPAALPSASPPPREVPVPTPAPVEVPVPERVAGSPVTPLPEQEASPARP 1118
Query: 1844 -----------PLRPDSGSA--PPPAPRSFSGARIKVPNYSPSRRPLGGVSFG-----PL 1885
PLRP A P PAPR +P P ++ VSF P
Sbjct: 1119 AGPTEESPPSAPLRPPEPPAGPPAPAPRPDERPSSPIPLLPPPKKRRKTVSFSAIEVVPA 1178
Query: 1886 PSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRW-----------ASPPLK 1934
P P + P P R+ R PL W A +
Sbjct: 1179 PEPPPATPPQAKFPGPASRKAPRGVERTIRNLPLDHASLVKSWPEEVSRGGRSRAGGRGR 1238
Query: 1935 TSPQLRVPPPTSV------VTALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSA 1988
+ + P T V ALTP L P PA + + E +
Sbjct: 1239 LTEEEEAEPGTEVDLAVLADLALTPARRGL-PALPAVEDSEATETSDEAERPRPLLSHIL 1297
Query: 1989 ADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLA 2048
+ ++A ++ T P A A+ P ++ SSP + P VV+ A
Sbjct: 1298 LEHNYALAVKPTPP-------APALRPPEPVPAPAA-LFSSPADEVLEAPEVVVAE---A 1346
Query: 2049 PSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPED 2108
P + ++ +G ++G + E ++ + G G +R L + R RPP
Sbjct: 1347 EEPKPQQLQQQREEGEEEGEEEGEEEEEESSDSSSSSDGEGALRRRSLRSHARRRRPPPP 1406
Query: 2109 LP 2110
P
Sbjct: 1407 PP 1408
Score = 40.0 bits (92), Expect = 0.031
Identities = 84/381 (22%), Positives = 124/381 (32%), Gaps = 102/381 (26%)
Query: 499 PSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVE 558
P AT P +P + F + ++ P S + + + P + PP+PP+
Sbjct: 384 PRRATREEPPGAPFAENTAERFPPSYTSYLPPEPSRPTDQDYRPPAS--EAPPPEPPEPG 441
Query: 559 -------VSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVP----LPEKRRSILREP 607
SP R + TSP P PA SP T S P L + +L+E
Sbjct: 442 GGGGGGGPSPE-REEVRTSPR-PASPARSGSPAPETTNESVPFAQHSSLDSRIEMLLKEQ 499
Query: 608 TFRWTSLTREL------------------------------PPPPPAPPPPPAPSPPPAP 637
+++ L + PPP PA AP+ P
Sbjct: 500 RSKFSFLASDTEEEEENSSMVLGARDTGSEVPSGSGHGPCTPPPAPANFEDVAPTGSGEP 559
Query: 638 ATSSRRPLLLRAPQFTP----SEAHLKIYESVLTPPPLGAP-EAPEPEPPPADDSPAEPE 692
+ P Q +P + + + +PPP P + P P PPP P P
Sbjct: 560 GATRESPKANGQNQASPCSSGDDMEISDDDRGGSPPPAPTPPQQPPPPPPP----PPPPP 615
Query: 693 PRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQA 752
P SLP L P A LL P P
Sbjct: 616 PYLA------SLP---------------------LGYPPHQPAYLLPP--------RPDG 640
Query: 753 LPPPQPQLQPPPSPQQMPPLEKARI-----AGVGSLPLSGVEEKMFSLLKRAKVQLFKID 807
PPP+ PPP P + + A G +P+S F + + +L ++
Sbjct: 641 PPPPEYPPPPPPPPHIYDFVNSLELMDRLGAQWGGMPMS------FQMQTQMLTRLHQLR 694
Query: 808 QQQQQKVAASMPLSPGGQMEE 828
Q + A++ P PGG E
Sbjct: 695 QGKGLIAASAGP--PGGAFGE 713
Score = 38.1 bits (87), Expect = 0.12
Identities = 62/255 (24%), Positives = 76/255 (29%), Gaps = 47/255 (18%)
Query: 21 PGRPRGAGGGGGRGGRGNGAERVRVALRRGGGATG--PGGAEPGEDTALLRLLGLRRGLR 78
P P GGGGG GG E VR + R A P E + L +
Sbjct: 434 PPEPPEPGGGGGGGGPSPEREEVRTSPRPASPARSGSPAPETTNESVPFAQHSSLDSRIE 493
Query: 79 RLRRLWAGPRVQRGRGRGRGRGWGPSRGCVPEEESSDGESDEEEFQGFHSDEDVAPSSLR 138
L + QR + +SD E +EE SS+
Sbjct: 494 MLLK------EQRSKFSFL---------------ASDTEEEEEN------------SSMV 520
Query: 139 SALRSQRGRAPRGRGRKHKTTPLPPPRLADVAPTPPKTPARKRGEEGTERMVQA------ 192
R P G G T P P DVAPT P R QA
Sbjct: 521 LGARDTGSEVPSGSGHGPCTPPPAPANFEDVAPTGSGEPGATRESPKANGQNQASPCSSG 580
Query: 193 ----LTELLRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPC--RRKQQAVVVAEAAVT 246
+++ R P AP P P PP + P Q A ++
Sbjct: 581 DDMEISDDDRGGSPPPAPTPPQQPPPPPPPPPPPPPYLASLPLGYPPHQPAYLLPPRPDG 640
Query: 247 IPKPEPPPPVVPVKH 261
P PE PPP P H
Sbjct: 641 PPPPEYPPPPPPPPH 655
Score = 37.0 bits (84), Expect = 0.27
Identities = 52/226 (23%), Positives = 74/226 (32%), Gaps = 65/226 (28%)
Query: 1787 GPREEPAHLEAAEENQTIVHSPAPSS----EPPGGEDPPLDTDVLVPGAPERHSPIQNLD 1842
G R+ + + + + PAP++ P G +P + + SP + D
Sbjct: 522 GARDTGSEVPSGSGHGPCTPPPAPANFEDVAPTGSGEPGATRESPKANGQNQASPCSSGD 581
Query: 1843 PP--LRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPT 1900
D G +PPPAP +P ++P P P P P +P
Sbjct: 582 DMEISDDDRGGSPPPAP-------------TPPQQPP-----PPPPPPPPPPPYLASLPL 623
Query: 1901 VGDPDFPA---PPRRSRRPSPLAPRPPP-------------------SRWASPPLKTSPQ 1938
P PA PPR P P P PPP ++W P+ Q
Sbjct: 624 GYPPHQPAYLLPPRPDGPPPPEYPPPPPPPPHIYDFVNSLELMDRLGAQWGGMPMSFQMQ 683
Query: 1939 LRVPPPTSVVTALTP-------TSGELAPPGPA------PSPPPPE 1971
T ++T L + PPG A P PPP E
Sbjct: 684 ------TQMLTRLHQLRQGKGLIAASAGPPGGAFGEAFLPFPPPQE 723
Score = 36.2 bits (82), Expect = 0.45
Identities = 27/74 (36%), Positives = 35/74 (47%), Gaps = 8/74 (10%)
Query: 359 QKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLP 418
Q+L + EE EEE ++EGEE+EE + ++ E L L A PP P
Sbjct: 1352 QQLQQQREEG--EEEGEEEGEEEEEESSDSS---SSSDGEGALRRRSLRSHARRRRPPPP 1406
Query: 419 PPSTSPPPPLCPPP 432
PP PPPP P
Sbjct: 1407 PP---PPPPRAYEP 1417
Score = 34.7 bits (78), Expect = 1.3
Identities = 34/134 (25%), Positives = 42/134 (31%), Gaps = 30/134 (22%)
Query: 2178 GPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTS------ 2231
GP PP PA F +A G P ++ P + +P S
Sbjct: 537 GPCTPPPAPAN------------FEDVAPTGSGEPGATRESPKANGQNQASPCSSGDDME 584
Query: 2232 -------WTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKRVSTF 2284
+ PP P P P PPPPPPP + S PP Q +
Sbjct: 585 ISDDDRGGSPPPAPTPPQQPP-----PPPPPPPPPPPYLASLPLGYPPHQPAYLLPPRPD 639
Query: 2285 SGRSPPAPPPYKAP 2298
P PPP P
Sbjct: 640 GPPPPEYPPPPPPP 653
Score = 34.7 bits (78), Expect = 1.3
Identities = 17/62 (27%), Positives = 28/62 (45%)
Query: 355 KKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPP 414
+++E+ ++ EEE +EEEE+ + + A + PPPP PP P
Sbjct: 1356 QQREEGEEEGEEEGEEEEEESSDSSSSSDGEGALRRRSLRSHARRRRPPPPPPPPPPRAY 1415
Query: 415 PP 416
P
Sbjct: 1416 EP 1417
Score = 34.3 bits (77), Expect = 1.7
Identities = 21/43 (48%), Positives = 21/43 (48%), Gaps = 7/43 (16%)
Query: 1029 PWDSDESPEAS----PGPPGPRRGAGAGGP---REEVVAHPGP 1064
P D D P AS P PP P G G GGP REEV P P
Sbjct: 420 PTDQDYRPPASEAPPPEPPEPGGGGGGGGPSPEREEVRTSPRP 462
Score = 32.3 bits (72), Expect = 6.5
Identities = 26/101 (25%), Positives = 43/101 (42%), Gaps = 9/101 (8%)
Query: 2339 RPGEPAGEESPGPLQERSPLLP-LPEDGPPQVPDGP--------PDLLLESQWHHYSGEA 2389
RP PA E+ P QE+ P P PP+ + L+S+ S E+
Sbjct: 913 RPSTPAEEDEDDPEQEKEAGEPGRPGTKPPKRDEERGKTQGKHRKSFALDSEGEEASQES 972
Query: 2390 SSSEEEPPSPDDKENQAPKRTGPHLRFEISSEDGFSVEAES 2430
SS ++E +D+E++ + + E DG E++S
Sbjct: 973 SSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDS 1013
Score = 32.3 bits (72), Expect = 6.5
Identities = 43/158 (27%), Positives = 56/158 (35%), Gaps = 36/158 (22%)
Query: 1031 DSDESPEASPGPPGPRRGAGAGGPREEVVAHPGPEEQDSLLQRKSARRCVKQRPSYDIF- 1089
+ +E P A P P PRE V P P E + + A V P +
Sbjct: 1066 EEEERPAALPSASPP--------PREVPVPTPAPVEVP--VPERVAGSPVTPLPEQEASP 1115
Query: 1090 -------EDSDDSEPGGPPAPRRRTPRENELPLPEPEEQSRPRKPTLQPVLQLKARRRLD 1142
E+S S P PP P P P P P+E+ P L P K R+ +
Sbjct: 1116 ARPAGPTEESPPSAPLRPPEPPAGPPA----PAPRPDERPSSPIPLLPP--PKKRRKTVS 1169
Query: 1143 KDAL----------APGPFASFPNGWTGKQKSPDGVHR 1170
A+ A P A FP +K+P GV R
Sbjct: 1170 FSAIEVVPAPEPPPATPPQAKFPG--PASRKAPRGVER 1205
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 133 bits (334), Expect = 3e-30
Identities = 157/604 (25%), Positives = 210/604 (34%), Gaps = 101/604 (16%)
Query: 381 KEERAV-AEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPP---PV 436
K+ RA A + +PA+ + PP TPP+P P P P +P PP PP P P
Sbjct: 919 KKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPA 978
Query: 437 SPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRG--RPPLTPSQRAEREAARAGPEGTS- 493
+P P +P PP A P PAT S K P +TP AA P+G S
Sbjct: 979 TPSPKGAPTPPAATPPS----PKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGAST 1034
Query: 494 PPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPK 553
PP TP + G P + T PK P A + + +P+ P
Sbjct: 1035 PPAATPPSPKGSP---AATPLPKGA-----------PTTPAAT---LPSPK-----GGPA 1072
Query: 554 PPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTS 613
P ++ +P PP T PP P+ PSP AP PP+ P P + L P +
Sbjct: 1073 TPSLKGAPT--PPAAT-PPSPKGGPATPSPKGAPMPPAATPPSP---KGGLATPPHKGAP 1126
Query: 614 LTRELPPPPP-----APPPPPAPSPPPAPATSSRRPLLLRAPQ---FTPSEAHLKIYESV 665
T PP P PPP AP+ P A S + L P+ TP+ +
Sbjct: 1127 TTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGL 1186
Query: 666 LTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRT---------NHLSLPRFAPVVTTPVK 716
TP P GAP P PP A P P+ T L+ P TTP
Sbjct: 1187 ATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1246
Query: 717 AEVSPHGAPA-----------------LSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQ 759
SP G PA L G T P A+ T P+ P P
Sbjct: 1247 TPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPP 1306
Query: 760 LQPPPSPQQMPPLEKARIAGVGSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMP 819
P P PP K G+ P G K P
Sbjct: 1307 KGAPTPPAATPPSPK---GSPGTPPPKGAPTPPAVTPPSPK----------------GTP 1347
Query: 820 LSPGGQMEEVAGAVKQISDRGPVRSEDESVEAKRERPS-GPESPVQGPRIKHVCRHAAVA 878
P G S GP + + + + P+ P SP +GP I +
Sbjct: 1348 TLPATTPSSKGGPTTPSSKEGP--TPPAATPSHKGGPAMTPPSPKRGPAIP-----SPKG 1400
Query: 879 LGQARAMVPEDVPRLSALPLRDRQDLATEDTSSASETESVPSRSRRGKVEAAGPGGESEP 938
+ A++P + A P+ R+ AT + P ++ +A GG + P
Sbjct: 1401 DPTSPAVIPLSPKKAPATPV-TREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATP 1459
Query: 939 TGSG 942
+ G
Sbjct: 1460 SSKG 1463
Score = 115 bits (288), Expect = 6e-25
Identities = 115/411 (27%), Positives = 158/411 (38%), Gaps = 57/411 (13%)
Query: 392 PAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPP---PVSPPPLPSPPPPP 448
PA + PP TPP+P P PPP +P PP PP P P P PS P
Sbjct: 1301 PATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGP 1360
Query: 449 AQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPE 508
+E P P PA +G P +TP +R A P+G PT +P+ P +
Sbjct: 1361 TTPSSKEGPTP--PAATPSHKGGPAMTPPS-PKRGPAIPSPKG--DPT-SPAVIPLSPKK 1414
Query: 509 DSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVL---RP 565
T + + P V+ S + K P + P P + P L P
Sbjct: 1415 APATPVTREGAATPSKGDLTPPAVTPVSLK--KAPATSAPKGGPATPSSKGDPTLPAVTP 1472
Query: 566 PITTSPPVPQEPAPVPSPPRAP-TP-----PSTPVPLPEKRRSILREPTFR-------WT 612
P PP P++ A SP +AP TP P+ P +P + + P+ R T
Sbjct: 1473 PSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTAT 1532
Query: 613 SLTRELPP---------PP----PAPPPPPA-PSPPPAPATSSRR----PLLLRAPQF-- 652
L+++ P PP P+P PA P+P APAT S + P + +
Sbjct: 1533 LLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKG 1592
Query: 653 TPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVT 712
PS L I +V +P P AP P PP + PA P P+ P PV
Sbjct: 1593 APSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGT--------PTSPPVTP 1644
Query: 713 TPVK-AEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQP 762
+ +K + SP QA P + T L + L P P+ P
Sbjct: 1645 SSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPT-ALKEVLVAPAPESTP 1694
Score = 110 bits (274), Expect = 2e-23
Identities = 169/716 (23%), Positives = 230/716 (32%), Gaps = 115/716 (16%)
Query: 148 APRGRGRKHKTTPLPPPRLADV------APTPPK-TPARKRGEEGTERMVQALTELLRRA 200
+P+G TP P P+ APTPP TP +G T A T A
Sbjct: 935 SPKGAPTPPAATP-PSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTP---PA 990
Query: 201 QAPQAPRSRACEPS---TPRRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVV 257
P +P+ PS P PP P A T P P+ P
Sbjct: 991 ATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAAT 1050
Query: 258 PVKHQTGSWKCKEGPGP--GPGTPRRGG------QSSRGGRGGRGRGRGGGLPFVIKFVS 309
P+ + P P GP TP G + +GG G P
Sbjct: 1051 PLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATP 1110
Query: 310 RAKKVKMGQLSLGLESGQGQGQHEESWQDVPQRRVG------SGQGGSPCWKKQEQKLDD 363
+ K GL + +G P + G G +P K
Sbjct: 1111 PSPKG-------GLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGL 1163
Query: 364 EEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPL------------TPPAP 411
K + +A A A PP P T PA
Sbjct: 1164 ATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1223
Query: 412 SPPPP-----LPPPSTSPPPPLCPPPPP---PVSPPPLPSPPPPP----------AQEEQ 453
+PP P P P +P P PP P P +PPP +P PP A
Sbjct: 1224 TPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPH 1283
Query: 454 EESPPPVVPATCSRKRG----RPPLTPSQRAEREAARAGPEGTSPP--TPTPSTATGGPP 507
+ +P P V S K G P P+ A + G GT PP PTP T P
Sbjct: 1284 KGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSP 1343
Query: 508 EDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPI 567
+ +PT+ P +T K + SS+ TP P SP P I
Sbjct: 1344 KGTPTL-PATTPSSKG-------GPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAI 1395
Query: 568 TTSPPVPQEPAPVP-SPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTR--ELPPPPPA 624
+ P PA +P SP +AP P T + L P SL + P
Sbjct: 1396 PSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGG 1455
Query: 625 PPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPA 684
P P + P PA + P AP+ + + K ++ TP P+GAP P P
Sbjct: 1456 PATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPK--KAPATPAPMGAPTLPAVIPSSP 1513
Query: 685 DDSPAEPEPR------------------------AVGRTNHLSLPRFAPVVTTPVKAEVS 720
+ PA P R + + P+ P + TP +A +
Sbjct: 1514 KEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPAT 1573
Query: 721 PHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQP------PPSPQQMP 770
P A S+ P + + + L+P A+ P P+ P PPSP++ P
Sbjct: 1574 PSSKEA-SSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGP 1628
Score = 101 bits (252), Expect = 9e-21
Identities = 175/801 (21%), Positives = 238/801 (29%), Gaps = 136/801 (16%)
Query: 397 EEAKLPPPPLTPPAPSPPPPLPPPSTSPPP----PLCPPPPPPVSPPPLPSPPPPPAQEE 452
+E L PL P A P P P + P L P P V P LP PP ++
Sbjct: 691 KEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKK 750
Query: 453 QEE-------SPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPE----GTSPPTPTPST 501
+ +P P C + T S + P SP T P T
Sbjct: 751 VDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPT 810
Query: 502 ATGGPPEDSPT------VAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPP 555
G D+P V+P +FL P S +P PP P
Sbjct: 811 KKGSAGPDTPIGNLSSPVSPVEASFL--------PENSLSFQGSKDSPATTHSPTPPSPK 862
Query: 556 KVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTP---PSTPVPL-----------PEKRR 601
+ P +P + P PS P P P+TP P P+K R
Sbjct: 863 GAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKAR 922
Query: 602 SILREPTFRWTSLTRELPPPPPAPPPPP-----APSPPPAPATSSRRPLLLRAPQFTPSE 656
+ + + P PP A PP P PSP AP + P + TPS
Sbjct: 923 ATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSP 982
Query: 657 AHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVK 716
+ P P G P P P+ P + P P+ P TP
Sbjct: 983 KGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPS 1042
Query: 717 AEVSPHGAPALSNGPQTQAQLL------QPLQALQTQLLPQALPPPQPQ---LQPPPSPQ 767
+ SP P P T A L +L+ P A PP P+ P P
Sbjct: 1043 PKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGA 1102
Query: 768 QMPP--LEKARIAGVGSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQ 825
MPP + G+ + P G + K L + A+ P SP G
Sbjct: 1103 PMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG 1162
Query: 826 M--EEVAGAVKQISDRGPVRSEDESVEAKRERPSGPESPVQGPRIKHVCRHAAVALGQAR 883
+ GA + P + + + P+ P + P+ G
Sbjct: 1163 LATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK------------GGLA 1210
Query: 884 AMVPEDVPRL-SALPLRDRQDLATEDTSSASETESVPSRSRRGKVEAAGPGGESEPTGS- 941
P+ P +A P + LAT A T + S +G P G P +
Sbjct: 1211 TPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAAT 1270
Query: 942 ----GGTLAHTPRRSLPSHHGKKMRMARCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKK 997
G LA P + P+ V PK GGP T
Sbjct: 1271 PPSLKGGLATPPHKGAPN------------------------PAVVTPPSPK-GGPATS- 1304
Query: 998 QCCVYRKCDKIEARKMERLAKKGRTIVKTLLPWDSDESPEASPGPPGPRRGAGAGGPREE 1057
KG P SP+ SPG P P+ G P
Sbjct: 1305 -------------------PPKGAPTPPAATP----PSPKGSPGTPPPK-----GAPTPP 1336
Query: 1058 VVAHPGPEEQDSLLQRKSARRCVKQRPSYDIFEDSDDSEPGGPPAPRRRTPRENELP-LP 1116
V P P+ +L + + PS + P P P P +P
Sbjct: 1337 AVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIP 1396
Query: 1117 EPEEQSRPRKPTLQPVLQLKA 1137
P + P P + P+ KA
Sbjct: 1397 SP--KGDPTSPAVIPLSPKKA 1415
Score = 100 bits (249), Expect = 2e-20
Identities = 119/456 (26%), Positives = 158/456 (34%), Gaps = 86/456 (18%)
Query: 376 KEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPP--- 432
K+G + + P + E + LP L+ P T P P P P
Sbjct: 811 KKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAV 870
Query: 433 ----------PPPVSPPP----LPSPPPPPAQEEQEESPPPVVPATCSRK-RGRP----- 472
PP +P P LP P PA +++P + ++ +K R P
Sbjct: 871 TPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGI 930
Query: 473 PLTPSQR-------AEREAARAGPEGTSP---PTP---TPSTATGGPPEDSPTVAPKSTT 519
P +PS + A + + GP SP PTP TP + GGP SP AP
Sbjct: 931 PASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPA 990
Query: 520 FLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRP-------PITTSPP 572
S + +P+ PP + SP P P +PP
Sbjct: 991 ---------ATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPP 1041
Query: 573 VPQ-EPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPP---- 627
P+ PA P P APT P+ +P P+ + T + P PP A PP
Sbjct: 1042 SPKGSPAATPLPKGAPTTPAATLPSPKGGPA---------TPSLKGAPTPPAATPPSPKG 1092
Query: 628 -PPAPSP----------PPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEA 676
P PSP PP+P P AP TP+ + TPPP GAP
Sbjct: 1093 GPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPT-TPAATPPSPKGGLATPPPKGAPTT 1151
Query: 677 PEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPA--LSNGPQTQ 734
P PP A P P+ T + P + TP SP GAP + P +
Sbjct: 1152 PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATP-----SPKGAPTTPAATPPSPK 1206
Query: 735 AQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMP 770
L P P A PP PSP+ P
Sbjct: 1207 GGLATP-SPKGAPTTPAATPPSPKGGLATPSPKGAP 1241
Score = 90.5 bits (223), Expect = 2e-17
Identities = 150/613 (24%), Positives = 194/613 (31%), Gaps = 107/613 (17%)
Query: 1808 PAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKV 1867
P S G +D P T P +P + +P + PL P + PP + S +
Sbjct: 837 PENSLSFQGSKDSPATTHSPTPPSP-KGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPF 895
Query: 1868 PNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIP-----TVGDPDFPAPPRRSRRPSPLAPR 1922
P P+ P P S+T P T PA P P+P A
Sbjct: 896 PKEGPAT---------PAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAAT 946
Query: 1923 PP--------PS-RWA-SPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPED 1972
PP PS +WA +PP T P + P T PT PP P P P
Sbjct: 947 PPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKG-APTPPAATPPSPKGGPATPSP 1005
Query: 1973 LG----PDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEES 2028
G P +A AS T P A S G P + +
Sbjct: 1006 KGAPTPPAVTPPSPKGSPAATPFPKGAS---TPP-------AATPPSPKGSPAATPLPKG 1055
Query: 2029 SPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGP 2088
+PT+ P + +P P ATP + A P+G PP+
Sbjct: 1056 APTT-----PAATLPSPKGGP-ATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAAT 1109
Query: 2089 GVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAP-------- 2140
G L + P P+ L P GA + PP+P
Sbjct: 1110 PPSPKGGLATPPHKGAP--TTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPP 1167
Query: 2141 -------PLANGSQPSQGL-TASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKII 2192
P A P GL T SP T A P +P + + P P PA +
Sbjct: 1168 PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS 1227
Query: 2193 LVNKLGQVFVKMA----------GEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGV 2242
L K A +G P PP K P PP +P + P
Sbjct: 1228 PKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATP------ 1281
Query: 2243 LPVVGVVRPAPPPPPPPLTLVLSSGPA-SPPRQAIRVKRVSTFSGR-SPPAPPPYKAPRL 2300
P G PA PP P GPA SPP+ A + S + SP PPP AP
Sbjct: 1282 -PHKGAPNPAVVTPPSP-----KGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAP-- 1333
Query: 2301 DEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLP 2360
P V G + TP+ +G P P+ +E P P P
Sbjct: 1334 --------TPPAVTPPSPKGTPTLPATTPSSKG-----GPTTPSSKEGPTP----PAATP 1376
Query: 2361 LPEDGPPQVPDGP 2373
+ GP P P
Sbjct: 1377 SHKGGPAMTPPSP 1389
Score = 89.4 bits (220), Expect = 5e-17
Identities = 160/643 (24%), Positives = 212/643 (32%), Gaps = 90/643 (13%)
Query: 1807 SPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPR------SF 1860
SPA + P G PP T P +P + SP P P + +A P+P+ S
Sbjct: 1022 SPAATPFPKGASTPPAAT----PPSP-KGSPAATPLPKGAPTTPAATLPSPKGGPATPSL 1076
Query: 1861 SGARIKV------PNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPA------ 1908
GA P P+ G P +P SP P G P PA
Sbjct: 1077 KGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSP 1136
Query: 1909 ------PPRRSRRPSPLAPRPPPSRW-ASPPLKTSPQLRVPPPTSVVTALTPTSGELAPP 1961
PP + +P A P P A+PP K +P P S L S + AP
Sbjct: 1137 KGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPT 1196
Query: 1962 GPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPG 2021
PA +PP P+ + +A L P A S GGP
Sbjct: 1197 TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPA 1256
Query: 2022 DSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQ 2081
+ + +PT P GLA GAP V + A P+G
Sbjct: 1257 -TPPPKGAPTPPAATPPSL---KGGLATPPHKGAPNPAV---VTPPSPKGGPATSPPKGA 1309
Query: 2082 GTPPSGPGVVRAGVLGAAGDRARPPEDL---PSEIVDFVLKNLGGPGDGGAGPREESLPP 2138
TPP+ G G + P PS L GG P
Sbjct: 1310 PTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGP 1369
Query: 2139 APPLANGSQPSQGLTASPADPTRTFAWLPGAPG----VRVLSLGPAPEPPKPATSKIILV 2194
PP A S G +P P R A +P G V+ L P P P T +
Sbjct: 1370 TPPAATPSHKG-GPAMTPPSPKRGPA-IPSPKGDPTSPAVIPLSPKKAPATPVTREGAAT 1427
Query: 2195 NKLGQ--------VFVKMA--------------GEGEP-----VPPPVKQPPLPPTI-SP 2226
G V +K A +G+P PP K+PP P + +
Sbjct: 1428 PSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATS 1487
Query: 2227 TAPTSWTLPPGP-----LLGVLPVVGVVRPAPP-----PPPPPLTLVLSSGPAS-PPRQA 2275
++P P P L V+P PA P P P TL+ PA+ P++A
Sbjct: 1488 SSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEA 1547
Query: 2276 IRVKRVSTFSGRSPPA-PPPYKAPRLDEDGEASEDTPQVPGLGSGGFS-RVRMKTPTVRG 2333
+ ++ S + PA P P +AP EAS P G S + + P V
Sbjct: 1548 LIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTS 1607
Query: 2334 VLDLDRPGEPAGEESPGPLQERSPLLPLPEDGPPQVPDGPPDL 2376
+ P PA P E+ P P P+ P P P L
Sbjct: 1608 PSPKEAPTPPA---VTPPSPEKGPATPAPKGTPTSPPVTPSSL 1647
Score = 87.0 bits (214), Expect = 2e-16
Identities = 178/751 (23%), Positives = 256/751 (34%), Gaps = 133/751 (17%)
Query: 162 PPPRLADVAPTPPK-TPARKRGEEGTERMVQALTELLRRAQAPQ----------APRSRA 210
PPP+ APTPP TP +G T A + +P+ AP A
Sbjct: 1258 PPPK---GAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPA 1314
Query: 211 CEPSTPRRSRGRPP--GRPAGPCRRKQQAVVVAEAAVTIPKPEPPP--PVVPVKHQTGSW 266
P +P+ S G PP G P P AVT P P+ P P + G
Sbjct: 1315 ATPPSPKGSPGTPPPKGAPTPP-------------AVTPPSPKGTPTLPATTPSSKGGPT 1361
Query: 267 --KCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGGLPFVIKFVSRAKKVKMGQLSLGLE 324
KEGP P TP G + + RG +P + + +
Sbjct: 1362 TPSSKEGPTPPAATPSHKGGPAMTPPSPK---RGPAIPSPKGDPTSPAVIPLSPKKAPAT 1418
Query: 325 SGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQKLDDEEEEKKEEEEKDKEGEEKEER 384
+G S D+ V KK +G
Sbjct: 1419 PVTREGAATPSKGDLTPPAV------------------TPVSLKKAPATSAPKGGPATPS 1460
Query: 385 AVAEEMMPAAEKEEAKLPPPP---LTPPAPSPPPPLPPPSTSPPPPLCPPPPP---PVSP 438
+ + +PA K PP P T +P P P P +P P P P P +P
Sbjct: 1461 SKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATP 1520
Query: 439 PPLPSPPPPPAQEEQEESPPP-------VVPATCSRKRGRPPLTPSQRAEREAARAGPEG 491
P P A +++P + PA + P P+ + E A + E
Sbjct: 1521 SSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPK-EAPATPSSKEA 1579
Query: 492 TSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDP 551
+SPP TPST G P +PK I P V++ S + TP P
Sbjct: 1580 SSPPAVTPSTYKGAP-------SPKEL--------LIPPAVTSPSPKEAPTPPAV---TP 1621
Query: 552 PKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRA------PTPPSTPVPLPEKR----- 600
P P K +P + T+ P P P+ P + T P LP K+
Sbjct: 1622 PSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTAL 1681
Query: 601 RSILREPTFRWTSL----TRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAP------ 650
+ +L P T + TR+ P + P P P+ S+ PL AP
Sbjct: 1682 KEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPV 1741
Query: 651 QFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPA---DDSPAEPEPRAVGR--TNHLSLP 705
Q S+ S PL PE+ P A + +PE +V + +SLP
Sbjct: 1742 QKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLP 1801
Query: 706 RF-APVVTTPVKAEVSPHG------APALSNGPQTQAQLL-----QPLQ-ALQTQLLPQA 752
+PV T P K + P +P+ P + +LL +P+ + Q +
Sbjct: 1802 LAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVN 1861
Query: 753 LPPPQPQLQPPPSPQQMPPLEKARIAGVGSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQ 812
+P P+ P P+P P+ K GS S +E + L ++ Q QQ Q
Sbjct: 1862 MPTPKSAGIPVPTPSAKQPVTK---NNKGSGTESDSDESVPELEEQDSTQ--ATTQQAQL 1916
Query: 813 KVAASM---PLSPGGQMEEVAGAVKQISDRG 840
AA + P+S Q A K +S G
Sbjct: 1917 AAAAEIDEEPVSKAKQSRSEKKARKAMSKLG 1947
Score = 83.2 bits (204), Expect = 3e-15
Identities = 166/713 (23%), Positives = 233/713 (32%), Gaps = 125/713 (17%)
Query: 162 PPPRLADVAPTPPKTPARKRGEEGTERMVQALTELLRRAQAPQAPRSRACEPS---TPRR 218
PPP+ A TP TP +G T A T A P +P+ PS P
Sbjct: 1166 PPPKGAPT--TPAATPPSPKGGLATPSPKGAPTT---PAATPPSPKGGLATPSPKGAPTT 1220
Query: 219 SRGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPE-----PPPPVVPVKHQTGSWKCKEGPG 273
PP G + AA T P P+ PPP P K G
Sbjct: 1221 PAATPPSPKGGLATPSPKGAPTTPAA-TPPSPKGGPATPPPKGAPTPPAATPPSLKGGLA 1279
Query: 274 PGP--GTPRRGGQSSRGGRGGRGRGRGGGLPFVIKFVSRAKKVKMGQLSLGLESGQGQGQ 331
P G P + +GG G P + K G
Sbjct: 1280 TPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGT------------- 1326
Query: 332 HEESWQDVPQRRVGSGQGGSPCWKKQEQKLDDEEEEKK--EEEEKDKEGEEKEERAVAEE 389
P + + +P K L K KEG + +
Sbjct: 1327 -------PPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHK 1379
Query: 390 ----MMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPP--------PPLCPPPPPPVS 437
M P + K +P P P +P+ P P + + P P PP V+
Sbjct: 1380 GGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVT 1439
Query: 438 PPPLPSPPPPPAQEEQEESP----PPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTS 493
P L P A + +P P +PA PP P Q A + + P +
Sbjct: 1440 PVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPP-APKQVATSSSPKKAPATPA 1498
Query: 494 P-PTPTPSTATGGPPEDSPT--------VAPKSTTFLKNIRQFIMP----------VVSA 534
P PT P++ P +AP +T K + P V S
Sbjct: 1499 PMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSP 1558
Query: 535 RSSRVIKTPRRFMDEDPPKPPKVEVS--PVLRPPITTSPPVPQE---PAPV--PSPPRAP 587
+ + I TP+ E P P E S P + P P P+E P V PSP AP
Sbjct: 1559 KKTPAIPTPK----EAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAP 1614
Query: 588 TPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSP-PPAPATSSRRPLL 646
TPP+ P PEK + T + P PP P SP PA T +
Sbjct: 1615 TPPAVTPPSPEKGPA---------TPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATV 1665
Query: 647 LRAPQFTPS-EAHLKIYESVLTPPPLGAP-------EAPEPEPPPADDSPAEPEPRAV-G 697
+A + P+ + + E ++ P P P + P+ + A P P+P A G
Sbjct: 1666 PQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNG 1725
Query: 698 RTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQ-----TQAQLLQPLQALQ-TQLLPQ 751
LS AP++ + + G A S+ P+ +++ PL A ++LP+
Sbjct: 1726 SKGPLSTVAPAPLLPVQKDSSKTAKGKDA-SHSPKGPLAPPESKASTPLTAAAFEKVLPK 1784
Query: 752 -------ALPPPQPQLQPPPSP-------QQMPPLEKARIAGVGSLPLSGVEE 790
A P P L PSP QQ P + S PL+ +E
Sbjct: 1785 PESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADE 1837
Score = 81.3 bits (199), Expect = 1e-14
Identities = 184/841 (21%), Positives = 279/841 (33%), Gaps = 145/841 (17%)
Query: 134 PSSLRSALRSQRGRAPRGRGRKHKTTPLPPPRLADVAPTPPK--------TPARKRGEEG 185
P SL+ L + P +G + PP A +PPK TP +G G
Sbjct: 1271 PPSLKGGLAT-----PPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPG 1325
Query: 186 TERMVQALTELLRRAQAPQAPRSRACEPSTPRRSRGRP--------PGRPAGPCRRKQQA 237
T A T A P +P+ P+T S+G P P PA K
Sbjct: 1326 TPPPKGAPTP---PAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGP 1382
Query: 238 VVVAEA-----AVTIPKPEPPPPVV-----------PVKHQTGSWKCKEGPGPGPGTP-- 279
+ + A+ PK +P P V PV + + K P TP
Sbjct: 1383 AMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVS 1442
Query: 280 RRGGQSSRGGRGGRGRGRGGGLPFVIKFVSRAKKVKMGQLSLGLESGQGQGQHEESWQDV 339
+ ++ +GG G P + + K + S + +
Sbjct: 1443 LKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGA 1502
Query: 340 PQRRVGSGQGGSPCWKKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEA 399
P + D +K +E + M + K+
Sbjct: 1503 PTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTP 1562
Query: 400 KLPPPPLTPPAPS----PPPPLPPPST-----SPPPPLCPPPPPPVSPPPLPSPP--PPP 448
+P P P PS PP PST SP L PP SP P+PP PP
Sbjct: 1563 AIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPP 1622
Query: 449 AQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPE 508
+ E+ +P P T PP+TPS + + A T P + G P +
Sbjct: 1623 SPEKGPATPAPKGTPT------SPPVTPSSLKDSPTSPASVTCKMGAT-VPQASKGLPAK 1675
Query: 509 DSPTV--------APKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVS 560
PT AP+ST P+++A + + +T ++ PP P
Sbjct: 1676 KGPTALKEVLVAPAPEST-----------PIITAPTRKGPQT-KKSSATSPPICPDPSAK 1723
Query: 561 PVLRPPITTSPPVPQEPAPVPSPPR-----APTPPSTPVPLPEKRRSILREPTFRWTSLT 615
+ P++T P P P S A P P+ PE + S T +
Sbjct: 1724 NGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKAS-----TPLTAAAF 1778
Query: 616 RELPPPPPAPPPPPAPSPPPA-PATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAP 674
++ P P + APSPP + P S P L QF PS L VL P P
Sbjct: 1779 EKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGL-----VLESP--SKP 1831
Query: 675 EAPEPEPPPADDSPAEPEPRAVGRTN---HLSLPRFA--PVVTTPVKAEV---------- 719
AP E P EP V + ++ P+ A PV T K V
Sbjct: 1832 LAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTE 1891
Query: 720 --SPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARI 777
S P L TQA Q A ++ + + + + + M L ++
Sbjct: 1892 SDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQV 1951
Query: 778 AGVGSLPLSGVEEKMFSLLK----------------RAKVQLFKIDQQQQQKVAASMPLS 821
GV + + + +F + K AK++ D QQ ++AA+
Sbjct: 1952 TGVTRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIE----DLSQQAQLAAAEKFK 2007
Query: 822 PGGQMEEVAGAVKQISDRGPVRSEDESVEAKRERPSGPESPVQGPRIKHVCRHAAVALGQ 881
G+ AV I + ++ +V+ + E E+ V+ I+ V A V+ +
Sbjct: 2008 VQGE------AVSNIQE----NTQTPTVQEESEEEEVDETGVEVKDIELVMSQANVSRAK 2057
Query: 882 A 882
A
Sbjct: 2058 A 2058
Score = 71.6 bits (174), Expect = 1e-11
Identities = 151/659 (22%), Positives = 203/659 (30%), Gaps = 89/659 (13%)
Query: 1785 PWGPREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPP 1844
P G PA + + P + PP P L + P P + +P + P
Sbjct: 1237 PKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATP--PHKGAPNPAVVTP 1294
Query: 1845 LRPDSGSA--PPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVG 1902
P G A PP + A P SP P G P +P SP T +P
Sbjct: 1295 PSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKG-TPTLPATT 1353
Query: 1903 DPDFPAPPRRSRRPSPLAPRPPPSRWASPPL-----KTSPQLRVPPPTSVVTALTPTSGE 1957
P S + P P PS P + K P + P A+ P S +
Sbjct: 1354 PSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPK 1413
Query: 1958 LAPPGP----APSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAM 2013
AP P + P DL P V+ +S L P A
Sbjct: 1414 KAPATPVTREGAATPSKGDLTP-----PAVTPVS----------LKKAPATSAPKGGPAT 1458
Query: 2014 GSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAE 2073
SS G P + SP V S+P AP ATP L V + E
Sbjct: 1459 PSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAP-ATPAPMGAPTLPAVIPSSPKEVP 1517
Query: 2074 AVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPRE 2133
A R P+ + + P P E + + P A P
Sbjct: 1518 ATPSSRRDPIAPTATLL----------SKKTPATLAPKEALIPPAMTVPSPKKTPAIPTP 1567
Query: 2134 ESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPA---PEPPKPATSK 2190
+ P P S P P T + GAP + L + PA P P + T
Sbjct: 1568 KEAPATPSSKEASSP----------PAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPP 1617
Query: 2191 IILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVR 2250
+ + A +G P PPV L SPT+P S T G +P
Sbjct: 1618 AVTPPSPEKGPATPAPKGTPTSPPVTPSSLKD--SPTSPASVTCKMG---ATVPQASKGL 1672
Query: 2251 PAPPPPPPPLTLVLSSGPAS------PPRQAIRVKRVSTFS-----------GRSPP--- 2290
PA P ++++ P S P R+ + K+ S S G P
Sbjct: 1673 PAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLST 1732
Query: 2291 -APPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESP 2349
AP P + D A G + TP + P + S
Sbjct: 1733 VAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSA 1792
Query: 2350 GPLQERSPLLPLPEDGPPQVPDGPP-DLLLESQWHHYSGEASSSEEEPPSPDDKENQAP 2407
P SP + LP P VP PP L S G S +P +P D++ P
Sbjct: 1793 AP----SPPVSLPL-APSPVPTLPPKQQFLPSS----PGLVLESPSKPLAPADEDELLP 1842
Score = 70.1 bits (170), Expect = 3e-11
Identities = 107/420 (25%), Positives = 146/420 (34%), Gaps = 79/420 (18%)
Query: 2042 VSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRA--GVLGAA 2099
V +P L P+ TP P +++DG+ T + A P+ T SG + G L
Sbjct: 734 VPSPSLPPAGTP--PGTKKVDGISH-TSALAPVASSPKECPTEDSGASATASSKGTLTYL 790
Query: 2100 GDRA------------RPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLA-NGS 2146
D RPP S D + NL P P E S P L+ GS
Sbjct: 791 ADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSP----VSPVEASFLPENSLSFQGS 846
Query: 2147 QPSQGLTASPADPTRTFAWLPGA----------------PGVRVLSL-----GPAPEPPK 2185
+ S T SP P+ A P A P V++L GPA PK
Sbjct: 847 KDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPK 906
Query: 2186 PATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPV 2245
A + + + + A +G P P K P PP +P +P P P P
Sbjct: 907 QAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTP- 965
Query: 2246 VGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGE 2305
PA PP P GPA+P S +PPA P +P+
Sbjct: 966 -----PAATPPSP------KGGPATP----------SPKGAPTPPAATP-PSPKGGPATP 1003
Query: 2306 ASEDTPQVPGLGSGGFSRVRMKTPTVRGVL--DLDRPGEPAGEESPGPLQERSP-----L 2358
+ + P P + TP +G P P G + PL + +P
Sbjct: 1004 SPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAAT 1063
Query: 2359 LPLPEDGP--PQVPDGPPDLLLESQWHHYSGEASSSEEEPPSPDDKENQAPK---RTGPH 2413
LP P+ GP P + G P + G A+ S + P P +PK T PH
Sbjct: 1064 LPSPKGGPATPSL-KGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPH 1122
Score = 57.8 bits (138), Expect = 1e-07
Identities = 96/401 (23%), Positives = 140/401 (34%), Gaps = 102/401 (25%)
Query: 405 PLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPAT 464
PL AP P S+SP PL P AT
Sbjct: 561 PLVQAAPKNSPSFQSTSSSPEIPLSP-------------------------------EAT 589
Query: 465 CSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNI 524
++K PL + A + G ++ T S A GP P + KS+ +
Sbjct: 590 LAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYA--GPDSAGPLL--KSSLITPTV 645
Query: 525 RQF---------IMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVP- 574
F + P + +S T F++ PK PV +TT P VP
Sbjct: 646 AAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNH--PVKEGTLTTLPLVPT 703
Query: 575 -QEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSP 633
E PV AP+P +T PL L E+P P+P PPA +P
Sbjct: 704 ASENCPV-----APSPQNTCAPLAT-------------LVLAPEIPKSVPSPSLPPAGTP 745
Query: 634 PPAPA------TSSRRPLLLRAPQFTPSE----AHLKIYESVLT-----PPPLGAPEAPE 678
P TS+ P + +P+ P+E + + LT P PLG +P+
Sbjct: 746 PGTKKVDGISHTSALAP-VASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQ 804
Query: 679 PEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHG---------APALSN 729
+ PP A P+ +LS P +PV+A P +PA ++
Sbjct: 805 TKRPPTKKGSAGPDT----PIGNLSSP------VSPVEASFLPENSLSFQGSKDSPATTH 854
Query: 730 GPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMP 770
P + P + T L P+ + P P+ P PS +P
Sbjct: 855 SPTPPSPKGAPTPSAVTPLSPKGVTLP-PKETPTPSVVNLP 894
Score = 50.1 bits (118), Expect = 3e-05
Identities = 100/445 (22%), Positives = 146/445 (32%), Gaps = 43/445 (9%)
Query: 378 GEEKEERAVAEEMMPAAEKEEAKLPPPP---LTPPAPSPPPPLPPPSTSPPPPLCP---- 430
GE E E+ +P + E A LP +T P P LPPP SP P CP
Sbjct: 3 GEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPC-SPAPQQCPLSAA 61
Query: 431 ------PPPPPVSPPPLPSP-PPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAERE 483
P P ++ PL P P + P P G PP++P+ A
Sbjct: 62 NQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIG-PPISPAALALAS 120
Query: 484 AARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTP 543
A +P + P P KS+ F N+ V A S VI
Sbjct: 121 PMIAPTLKGTPSSSAPLALVALAPHS----VQKSSAFPPNLLTSPPSVAVAESGSVITLS 176
Query: 544 RRFMDEDP-PKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRS 602
+P KV V P T SPP P + S LP+ +
Sbjct: 177 APIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPT 236
Query: 603 ---ILREPTFRWTSLTREL-PPPPPAPPPPPAPSPPPAPATSSRRPLLL------RAPQF 652
+ P + T+++ L P P P PPA + S + L + A
Sbjct: 237 TTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPN 296
Query: 653 TPSEAHLKI--YESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPV 710
TP + + + + + L G+ + P A P + S P V
Sbjct: 297 TPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSV 356
Query: 711 V--------TTPVKAEVSPHGAPALSNGPQTQAQL-LQPLQALQTQLLPQALPPPQPQLQ 761
+ P P AP++ GP T + + P +L P L+
Sbjct: 357 IPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILK 416
Query: 762 PPPSPQQMPPL-EKARIAGVGSLPL 785
P+ PL + ++ VG+ PL
Sbjct: 417 SSPNATYHYPLVAQMPVSSVGTTPL 441
Score = 40.0 bits (92), Expect = 0.031
Identities = 72/323 (22%), Positives = 121/323 (37%), Gaps = 53/323 (16%)
Query: 512 TVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDP--PKPPKVEVSPVLRPPITT 569
T+A TT + P+ S S + T + P PK P +V+ LR P++
Sbjct: 448 TIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSP 507
Query: 570 SPPVPQE---------------------PAPVPSPPRAP-----TPPSTPVPLPEKRRSI 603
P P++ PA + P +P T P LP + +
Sbjct: 508 PLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAP 567
Query: 604 LREPTFRWTSLTRELPPPPPAPPPPPA---PSPPPAPATSSRRPL-------LLRAPQFT 653
P+F+ TS + E+P P A + P P PA+S PL +++ +
Sbjct: 568 KNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYA 627
Query: 654 -PSEAHLKIYESVLTPP----PLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSL-PRF 707
P A + S++TP PL + + P A + + +SL P+
Sbjct: 628 GPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKN 687
Query: 708 APV----VTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQ-PQLQP 762
PV +TT + P + T A L + A + +P+++P P P
Sbjct: 688 HPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPE---IPKSVPSPSLPPAGT 744
Query: 763 PPSPQQMPPL-EKARIAGVGSLP 784
PP +++ + + +A V S P
Sbjct: 745 PPGTKKVDGISHTSALAPVASSP 767
Score = 36.2 bits (82), Expect = 0.45
Identities = 52/193 (26%), Positives = 73/193 (37%), Gaps = 35/193 (18%)
Query: 1899 PTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGEL 1958
PT+ P PAP + PL+ S + SP S L VP P S +SG
Sbjct: 43 PTLPPPCSPAPQQ-----CPLSAANQASPFPSPSTIASTPLEVPFPQS-------SSGTA 90
Query: 1959 APPGPAPSPPP--PEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSS 2016
P G AP P P +GP + L+ A A +L GT P +A A+
Sbjct: 91 LPLGTAPEAPTFLPNLIGPPISP----AALALASPMIAPTLKGT-PSSSAPLALVAL--- 142
Query: 2017 HGGPGDSSEEESSPTSRYIHFPVTVVSAPG----LAPSATPGAPRIEQLDGVDDGTDSEA 2072
P + + P + P V+ G L+ P P+ L+ V +
Sbjct: 143 --APHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPK-TNLNKV------PS 193
Query: 2073 EAVQQPRGQGTPP 2085
E V P+G +PP
Sbjct: 194 EVVPNPKGTPSPP 206
Score = 35.0 bits (79), Expect = 1.0
Identities = 45/183 (24%), Positives = 58/183 (31%), Gaps = 26/183 (14%)
Query: 126 FHSDEDVAPSSLRSALRSQRGRAPRGRGRKHKTTPLPPPRLADV----APTPPK-TPARK 180
F + P+ ++ S +P+ K + TP P A APTPP TP
Sbjct: 895 FPKEGPATPAPKQAPALSMTSSSPK----KARATPAPKGIPASPSPKGAPTPPAATPPSP 950
Query: 181 RGEEGTERMVQALTELLRRAQAPQAPRSRACEPS---TPRRSRGRPPGRPAGPCRRKQQA 237
+G T A T A P +P+ PS P PP GP +
Sbjct: 951 KGGPATPSPKWAPTP---PAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKG 1007
Query: 238 VVV-----------AEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSS 286
+ AA PK PP GS P P TP S
Sbjct: 1008 APTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSP 1067
Query: 287 RGG 289
+GG
Sbjct: 1068 KGG 1070
Score = 33.1 bits (74), Expect = 3.8
Identities = 42/160 (26%), Positives = 60/160 (37%), Gaps = 22/160 (13%)
Query: 132 VAPSSLRSALRSQRGRAPRGRGRKHKTTPLPPPRLADVAPTPPKTPARKRGEEGTERMVQ 191
V P SL+ A + AP+G G ++ P A P+P + PA K+ +
Sbjct: 1438 VTPVSLKKAPATS---APKG-GPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKA 1493
Query: 192 ALTELLRRAQAPQ-APRSRACEPSTPRR-----SRGRPPGRPAGPCRRKQQAVVVAEA-- 243
T AP AP A PS+P+ S R P P K+ +A
Sbjct: 1494 PATP------APMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEA 1547
Query: 244 ----AVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGPGTP 279
A+T+P P+ P + K + KE P TP
Sbjct: 1548 LIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTP 1587
Score = 32.0 bits (71), Expect = 8.5
Identities = 66/274 (24%), Positives = 93/274 (33%), Gaps = 49/274 (17%)
Query: 2109 LPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPG 2168
LP V LG PG P + P PL+ +Q S + S T P
Sbjct: 26 LPMSSALSVTAALGQPGPTLPPPCSPA-PQQCPLSAANQASPFPSPSTIASTPLEVPFPQ 84
Query: 2169 APGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTA 2228
+ L LG APE P L N +G P + P + PT+ T
Sbjct: 85 SSSGTALPLGTAPEAP------TFLPNLIGPPI-------SPAALALASPMIAPTLKGTP 131
Query: 2229 PTSWTLPPGPLLGVLPVVGVVRPAPPP---PPPPLTLVLSSG----------PASPPRQA 2275
+S P L+ + P A PP PP V SG P+ P
Sbjct: 132 SSS---APLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNL 188
Query: 2276 IRVKRVSTFSGRSPPAPP------PYK--APRLD-EDGEASEDTPQVPGLGSGGFSRVRM 2326
+V + + P+PP PY P + G AS PQ + + ++
Sbjct: 189 NKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVAS--LPQTTPTTTLAIASPQV 246
Query: 2327 KTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLP 2360
K T+ VL ++PG L + P+ P
Sbjct: 247 KDTTISSVL--------ISPQNPGSLSLKGPVSP 272
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 126 bits (317), Expect = 3e-28
Identities = 116/430 (26%), Positives = 160/430 (37%), Gaps = 81/430 (18%)
Query: 380 EKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPP 439
E +R E A E P L PP P + P + S P P PPPPPP PP
Sbjct: 579 EAWKRGTQLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPP 638
Query: 440 PLPSPPPPPAQEEQ------EESPPPVVPATCSRKRG---------RPPLTPSQRAE--R 482
P P PPPPP Q +P V +T +R + +PP P +++ +
Sbjct: 639 PPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVK 698
Query: 483 EAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKT 542
P G PP P P PP +P A + P A S
Sbjct: 699 PQILVPPNGVVPPPPPP------PPPPTPGSAMAQ----------LKPAPCAPSLPQFSA 742
Query: 543 PRRFMDEDPPKPPKV-EVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRR 601
PP P K+ +V + + T PP P P P P PP+AP P +P P +
Sbjct: 743 --------PPPPLKIHQVQHITQVAPPTPPPPP--PIPAPLPPQAPPKPLVTIPAPTSTK 792
Query: 602 SILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKI 661
++ + + PP P PP PPA P PA+ + +P P
Sbjct: 793 TV--------APVVTQAAPPTPTPPVPPAKKQPAFPAS-----YIPPSPPTPPVP----- 834
Query: 662 YESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGR-TNHLSLPRFAPVVTT----PVK 716
+ PP L ++ +PPP SP P P V + + P P + + PV
Sbjct: 835 ----VPPPTLPKQQSFCAKPPP---SPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVP 887
Query: 717 AEVSPHGAPALSNGPQTQAQLL-------QPLQALQTQLLPQALPPPQPQLQPPPSPQQM 769
A V+P PA+ P+ Q + P + + P P P P PPP P
Sbjct: 888 ANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTAS 947
Query: 770 PPLEKARIAG 779
P +K+ G
Sbjct: 948 PTPDKSGSPG 957
Score = 120 bits (300), Expect = 2e-26
Identities = 136/514 (26%), Positives = 182/514 (35%), Gaps = 110/514 (21%)
Query: 372 EEKDKEGEEKEERAVAEEMMPAAEKEE------AKLPPPPLTPPAPSPPPPLPPPSTSPP 425
EE K E R + P + + + A P PPL PP P PPPP PPP PP
Sbjct: 588 EESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPP 647
Query: 426 P---------------------------------PLCPPPPPPVS--------------- 437
P L PP PPV
Sbjct: 648 PLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNG 707
Query: 438 ---PPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSP 494
PPP P PPP P + P P P+ PPL Q + + P P
Sbjct: 708 VVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQ--VQHITQVAPPTPPP 765
Query: 495 PTPTPSTATG-GPPEDSPTV-APKST-TFLKNIRQFIMPVVSARSSRVIKTPR---RFMD 548
P P P+ PP+ T+ AP ST T + Q P + K P ++
Sbjct: 766 PPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIP 825
Query: 549 EDPPKPPKVEVSPVL--------RPPITTSPPVPQ-------EPAPVPSPPRAPTPPSTP 593
PP PP P L +PP + PVP + P P+PP + P P
Sbjct: 826 PSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKP 885
Query: 594 VPL---PEKRRSILREPTFRWTSL---TRELPPPPPA-----PPPPPAP---SPPPAPAT 639
VP P+ ++ +P ++ +S+ + + PPPPP PPPPP+P PPP P T
Sbjct: 886 VPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPT 945
Query: 640 SSRRPLLLRAPQFTPSEAHLKIYESVLTPPPL----------GAPEAPEPEPPPADDSPA 689
+S P +P S+ + PPP E PEP+ P D +
Sbjct: 946 ASPTPDKSGSPGKKTSKTSSPGGKK---PPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVS 1002
Query: 690 EPEPRAV-GRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQL 748
+ P A G + +LP A P K +S P + A+ L
Sbjct: 1003 KFTPPAESGSPSKETLPPPA-APPKPGKLNLSGVNLPGVLQQGCVSAKA-PVLSGRGKDS 1060
Query: 749 LPQALPPPQPQLQPPPSPQQMPPLEKARIAGVGS 782
+ + PP PPP P+ PL I V S
Sbjct: 1061 VVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFS 1094
Score = 82.4 bits (202), Expect = 6e-15
Identities = 161/655 (24%), Positives = 223/655 (34%), Gaps = 149/655 (22%)
Query: 1796 EAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPP 1855
E+++ ++ P S PP P + T P + SP L PP P PPP
Sbjct: 589 ESSKARMESMNRPYTSLVPPLSPQPKIVT----PYTASQPSP--PLPPPPPPPPPPPPPP 642
Query: 1856 -----------APRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDP 1904
AP + S A + V + +R G L P +P + P
Sbjct: 643 PPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSV---KP 699
Query: 1905 DFPAPPRRSRRPSPLAPRPPPSRWASPPLKTS------PQLRVPPPTSVVTALTPTSGEL 1958
PP P P P PP A LK + PQ PPP + + + ++
Sbjct: 700 QILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHIT-QV 758
Query: 1959 APPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHG 2018
APP P P PP P L P +V T P
Sbjct: 759 APPTPPPPPPIPAPLPPQAPPKPLV----------------TIP---------------- 786
Query: 2019 GPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQP 2078
+PTS PV +AP P+ TP P + + A
Sbjct: 787 ----------APTSTKTVAPVVTQAAP---PTPTPPVPPAK-----------KQPAFPAS 822
Query: 2079 RGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPP 2138
+PP+ P V L P P V V+K + + PP
Sbjct: 823 YIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIA----------SQFPPP 872
Query: 2139 APPLANGSQPSQGLTA--SPADPTRTFA---WLPGAPGVRVLSLGPAPE-PPKPATSKII 2192
P A SQP + + A +P P A W P + V P+P+ PP P S ++
Sbjct: 873 PTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPV------PSPDFPPPPPESSLV 926
Query: 2193 LVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPA 2252
P P P PP PPT SPT S + PG G +P
Sbjct: 927 F------------PPPPPSPVPAPPPPPPPTASPTPDKSGS--PGKKTSKTSSPGGKKP- 971
Query: 2253 PPPPPPPLTLVLSSGPASP-PRQAIRVKRVSTFSGRSPPA----------PPPYKAPRLD 2301
PP P ++ SSG P P++ VS F +PPA PPP P+
Sbjct: 972 PPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKF---TPPAESGSPSKETLPPPAAPPK-- 1026
Query: 2302 EDGEASEDTPQVPGLGSGGFSRVRMKTPTVRG---VLDLDRPGEPAGEESPGPLQERSPL 2358
G+ + +PG+ G V K P + G ++ P P+ + P P E
Sbjct: 1027 -PGKLNLSGVNLPGVLQQGC--VSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETE-- 1081
Query: 2359 LPLPEDGPPQVPDG---PPDLLLESQWHHYSGEASSSEEEPPSPDDKENQAPKRT 2410
LPLP P V G P ++ Q +S S ++ PP K N + + T
Sbjct: 1082 LPLPPIEIPAVFSGNTSPKVAVVNPQPQQWS--KMSVKKAPPPTRPKRNDSTRLT 1134
Score = 81.6 bits (200), Expect = 9e-15
Identities = 105/401 (26%), Positives = 142/401 (35%), Gaps = 119/401 (29%)
Query: 391 MPAAEKEEAKLPPPPLTPPA--------------PSPPP-------------PLPPPSTS 423
+P+ K+ A PPP TPPA P PP P+P P
Sbjct: 858 VPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFP 917
Query: 424 PPPP-----LCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQ 478
PPPP PPPP PV PP P PP ++ SP T S +PP TP Q
Sbjct: 918 PPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTP-Q 976
Query: 479 RAEREAARAGPEGTSPPTP---------TPSTATGGPPEDS---PTVAPK------STTF 520
R + +G E P P TP +G P +++ P PK S
Sbjct: 977 RNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVN 1036
Query: 521 LKNIRQ-----FIMPVVSAR-SSRVIKTPRRFMDED-PPKPPKVE--VSPVLRPPI---T 568
L + Q PV+S R V++ P D D PP PP+ E + P+ P +
Sbjct: 1037 LPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGN 1096
Query: 569 TSP------PVPQE-------PAPVPSPPR------------------------APTPPS 591
TSP P PQ+ AP P+ P+ PT P
Sbjct: 1097 TSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPK 1156
Query: 592 T-----PVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLL 646
+ P L + R++ R+ R SL+ + P PPP P LL
Sbjct: 1157 SSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTATMDDMALPPPPP------ELL 1210
Query: 647 LRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDS 687
+ +H+ Y ++ PP P PP D +
Sbjct: 1211 SDQQKAGYGGSHISGYATLRRGPP--------PAPPKRDQN 1243
Score = 74.3 bits (181), Expect = 1e-12
Identities = 157/644 (24%), Positives = 204/644 (31%), Gaps = 145/644 (22%)
Query: 1814 PPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPS 1873
PP + + +LVP P + PP P PPP P S + A++K +PS
Sbjct: 689 PPVMQSQSVKPQILVP-------PNGVVPPPPPPP----PPPTPGS-AMAQLKPAPCAPS 736
Query: 1874 RRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPL 1933
P P HI V P P PP P+PL P+ PP
Sbjct: 737 LPQFSA------PPPPLKIHQVQHITQVAPPTPPPPPPI---PAPLPPQAPPK------- 780
Query: 1934 KTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDF 1993
P + +P PTS T + P + APP P P P PP P F + +
Sbjct: 781 ---PLVTIPAPTSTKT-VAPVVTQAAPPTPTP-PVPPAKKQPAFPASYIPPSPPTPPVPV 835
Query: 1994 AASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVS-APGLAPSAT 2052
L P Q+ A P S P V A P T
Sbjct: 836 PPPTL---PKQQSFCA------------------KPPPSPLSPVPSVVKQIASQFPPPPT 874
Query: 2053 PGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSE 2112
P A + L +P P P V+A P D P
Sbjct: 875 PPAMESQPL---------------KPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPP 919
Query: 2113 IVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAP-- 2170
+ L P P PP PP A+ + G T + P
Sbjct: 920 PPESSLVFPPPP----PSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTP 975
Query: 2171 ----GVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISP 2226
++ S PEP +P+ V+ L F A G P + LPP +P
Sbjct: 976 QRNSSIKSSSGAEHPEPKRPS------VDSLVSKFTPPAESGSP-----SKETLPPPAAP 1024
Query: 2227 TAPTSWTLPPGPLLGVL---------PVVG-------VVRPAPP-----PPPPPLTLV-- 2263
P L L GVL PV+ V P+PP PPPPP T +
Sbjct: 1025 PKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPL 1084
Query: 2264 -------LSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDE----DGEASED--- 2309
+ SG SP + + APPP + R D E SE
Sbjct: 1085 PPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTM 1144
Query: 2310 ---TPQVPGLGSGGFSRVRMKTPTVRGVL-DLDRPGEPAGEESPGPLQER-SPLLPLPED 2364
PQVP S G L DL+R + G L R S P
Sbjct: 1145 ATVVPQVPTSPKSSLS-------VQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTATM 1197
Query: 2365 GPPQVPDGPPDLLLESQ-----WHHYSGEASSSEEEPPSPDDKE 2403
+P PP+LL + Q H SG A+ PP+P ++
Sbjct: 1198 DDMALPPPPPELLSDQQKAGYGGSHISGYATLRRGPPPAPPKRD 1241
Score = 36.6 bits (83), Expect = 0.35
Identities = 40/165 (24%), Positives = 57/165 (34%), Gaps = 15/165 (9%)
Query: 674 PEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQT 733
PE+ +D ++ +P R+ + F+ + E S N P T
Sbjct: 544 PESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSKARMESMNRPYT 603
Query: 734 --------QAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGVGSLPL 785
Q +++ P A Q P PPP P PPP P PPL GS
Sbjct: 604 SLVPPLSPQPKIVTPYTASQPSP-PLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAP 662
Query: 786 SGVEEKMFSLLKRAKVQ---LFKIDQ---QQQQKVAASMPLSPGG 824
V+ + L+ A LFK Q Q V + + P G
Sbjct: 663 MFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNG 707
Score = 36.2 bits (82), Expect = 0.45
Identities = 30/122 (24%), Positives = 42/122 (34%), Gaps = 16/122 (13%)
Query: 160 PLPPPRLADVAPTPPKTPARKRGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPRRS 219
P PPP P PP P++ G+ + + R Q +P TP
Sbjct: 633 PPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTP--- 689
Query: 220 RGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGP-GPGT 278
P + + ++V V P P PPPP P GS + P P P
Sbjct: 690 -------PVMQSQSVKPQILVPPNGVVPPPPPPPPPPTP-----GSAMAQLKPAPCAPSL 737
Query: 279 PR 280
P+
Sbjct: 738 PQ 739
Score = 32.0 bits (71), Expect = 8.5
Identities = 35/123 (28%), Positives = 45/123 (36%), Gaps = 13/123 (10%)
Query: 160 PLPPPRLADVAPTP--PKTPARKRGEEGTE-RMVQALTELLRRAQAPQAPRSRACEPSTP 216
P P +A + P P P P + VQ +T++ P P P P
Sbjct: 719 PTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAP 778
Query: 217 RRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGP 276
+ P P K A VV +AA P P PPV P K Q ++ P P P
Sbjct: 779 PKPLVTIPA----PTSTKTVAPVVTQAA----PPTPTPPVPPAKKQP-AFPASYIP-PSP 828
Query: 277 GTP 279
TP
Sbjct: 829 PTP 831
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 125 bits (313), Expect = 7e-28
Identities = 99/355 (27%), Positives = 128/355 (36%), Gaps = 34/355 (9%)
Query: 392 PAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPL---CPPPPPPVSPPPLPSPPPP- 447
P+ PPP TP P PPP+T+P PP+ PPP PP +P PP
Sbjct: 1422 PSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPT 1481
Query: 448 --PAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPT----PST 501
P+ + PP P T P+TP P SPPT T P T
Sbjct: 1482 TTPSPPTTTTTTPP--PTTTPSPPTTTPITPPASTTTLPPTTTP---SPPTTTTTTPPPT 1536
Query: 502 ATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSP 561
T PP +P P STT L P + + TP P PP + +
Sbjct: 1537 TTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSP-PTTTTPSPPTITTT- 1594
Query: 562 VLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPP 621
PP TT+P P P P P+PP+T P + L T T PP
Sbjct: 1595 --TPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPP 1652
Query: 622 PPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAP---- 677
P P PP + P P T++ P P + ++ TP P P +P
Sbjct: 1653 PTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTT 1712
Query: 678 -------EPEPPP---ADDSP-AEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSP 721
P PPP SP P P T +P+ TTP+ ++P
Sbjct: 1713 TTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITP 1767
Score = 117 bits (292), Expect = 2e-25
Identities = 101/377 (26%), Positives = 128/377 (33%), Gaps = 43/377 (11%)
Query: 406 LTPPAPSPPPPLPPP--STSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPA 463
+T P+P P PPP +T+ PP P PP + P P+ P P PP P+
Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPS 1455
Query: 464 TCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPT----PSTATGGPPEDSPTVAPKSTT 519
PP T + SPPT T P T T PP +P P STT
Sbjct: 1456 PPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTT 1515
Query: 520 FLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAP 579
L P + + TP P P + P TT+P P
Sbjct: 1516 TLPPTTTPSPPTTTTTTPPPTTTP-----SPPTTTPITPPTSTTTLPPTTTPSPPPTTTT 1570
Query: 580 VPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPAT 639
P P P+PP+T P P + PT + T PPP P P + P P T
Sbjct: 1571 TPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPT 1630
Query: 640 SSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAP-EPEPPPADDSPAEPEPRAVGR 698
S+ P TPS + TPPP P P P P + P P
Sbjct: 1631 ST----TTLPPTTTPSPPP----TTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPS 1682
Query: 699 TNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQAL----P 754
+P+ TTP SP + P T P + T P + P
Sbjct: 1683 ---------SPITTTP-----SPPTTTMTTPSPTT-----TPSSPITTTTTPSSTTTPSP 1723
Query: 755 PPQPQLQPPPSPQQMPP 771
PP P P+ PP
Sbjct: 1724 PPTTMTTPSPTTTPSPP 1740
Score = 105 bits (263), Expect = 5e-22
Identities = 97/345 (28%), Positives = 120/345 (34%), Gaps = 56/345 (16%)
Query: 402 PPPPLT-----PPAPSPPPPL-----PPPSTSPPPPLCPPPPPPV--SPPPLPSPPPPPA 449
P PP+T PP +P PP+ PPP+T+P PP P PP SPP + PPP
Sbjct: 1438 PSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPT 1497
Query: 450 QEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPST----ATGG 505
+ P+ P S P TPS SPPT TP T T
Sbjct: 1498 TTPSPPTTTPITPPA-STTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTL 1556
Query: 506 PPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKT--PRRFMDEDPPK------PPKV 557
PP +P+ P +TT P + S I T P PP PP
Sbjct: 1557 PPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTT 1616
Query: 558 EVSPVLRPPIT-----------TSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILRE 606
SP PIT T+P P P P P+PP+T P P +
Sbjct: 1617 TPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPP 1676
Query: 607 PTFRWTSLTRELPPPP------PAPPPPPA--------------PSPPPAPATSSRRPLL 646
PT +S P PP P+P P+ PSPPP T+
Sbjct: 1677 PTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTT 1736
Query: 647 LRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEP 691
P T + S LT PL P P + +P P
Sbjct: 1737 PSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTP 1781
Score = 105 bits (261), Expect = 8e-22
Identities = 76/266 (28%), Positives = 100/266 (37%), Gaps = 19/266 (7%)
Query: 392 PAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPP---VSPPPLPSPPPPP 448
P+ PPP TP P+ P PP ST+ PP P PPP +PPP +P PP
Sbjct: 1523 PSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPT 1582
Query: 449 AQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPE 508
SPP + T P T + P T+P TP P++ T PP
Sbjct: 1583 T---TTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITP-PTSTTTLPPT 1638
Query: 509 DSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPIT 568
+P+ P +TT P + S TP + PP S PIT
Sbjct: 1639 TTPSPPPTTTT--------TPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPS----SPIT 1686
Query: 569 TSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPP 628
T+P P PSP P+ P T P + PT T P PP
Sbjct: 1687 TTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTT 1746
Query: 629 PAPSPPPAPATSSRRPLLLRAPQFTP 654
P+ +P T++ P + P F+P
Sbjct: 1747 LPPTTTSSPLTTTPLPPSITPPTFSP 1772
Score = 98.2 bits (243), Expect = 1e-19
Identities = 92/360 (25%), Positives = 114/360 (31%), Gaps = 84/360 (23%)
Query: 416 PLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLT 475
P+ T+P PP P PPP S LP P +PPP + PP+T
Sbjct: 1391 PMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPS-------PPIT 1443
Query: 476 PSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSAR 535
+ T PPT TPS PP + T P +TT
Sbjct: 1444 TTT-------------TPPPTTTPS-----PPISTTTTPPPTTT---------------- 1469
Query: 536 SSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVP 595
P PP SP TT+P P P P P+PP+T
Sbjct: 1470 ----------------PSPPTTTPSPP-----TTTPSPPTTTTTTPPPTTTPSPPTTTPI 1508
Query: 596 LPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPS 655
P + L T T PPP P PP +P P +++ P P TPS
Sbjct: 1509 TPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLP-----PTTTPS 1563
Query: 656 EAHLKIYESVLTPPPLGAPEAPE---PEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVT 712
+ TPPP P P P PP + P T + P P T
Sbjct: 1564 PPPT----TTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTP---PPTT 1616
Query: 713 TPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPL 772
TP +P P T L P PPP PP + PP+
Sbjct: 1617 TPSPPTTTPITPP-------TSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPI 1669
Score = 85.5 bits (210), Expect = 6e-16
Identities = 64/205 (31%), Positives = 80/205 (39%), Gaps = 25/205 (12%)
Query: 402 PPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSP---PPLPSPPPPPAQEEQEESPP 458
PPP TP P+ PPP+T+P PP P PP S PP +P PPP PP
Sbjct: 1596 PPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTP--PP 1653
Query: 459 PVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPS---TATGGPPEDSPTVAP 515
P+ + PP+T + T PPT TPS T T PP + T
Sbjct: 1654 TTTPSPPTTTTPSPPITTTT-------------TPPPTTTPSSPITTTPSPPTTTMTTPS 1700
Query: 516 KSTTFLKNIRQFIMPVVSARSS---RVIKTPRRFMDEDPPKPPKVEVSPVLRP-PITTSP 571
+TT I P + S + TP PP + P P+TT+P
Sbjct: 1701 PTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTP 1760
Query: 572 PVPQEPAPVPSPPRAPTPPSTPVPL 596
P P SP TP + VPL
Sbjct: 1761 LPPSITPPTFSPFSTTTPTTPCVPL 1785
Score = 80.9 bits (198), Expect = 2e-14
Identities = 100/417 (23%), Positives = 134/417 (32%), Gaps = 43/417 (10%)
Query: 392 PAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQE 451
P + P T P+P P T+ P P +P +P P
Sbjct: 3891 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3950
Query: 452 EQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTP-STATGGPPEDS 510
+P P T + P TP P GT PT TP +T T P +
Sbjct: 3951 TTTVTPTPTPTGTQT-----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 4005
Query: 511 PTVAPKSTTFLKNIRQFIMPVVSARSSRV-IKTPRRFMDEDPPKPPKVEVSPVLRPPITT 569
PT TT + P + ++ TP P P PITT
Sbjct: 4006 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 4065
Query: 570 SPPVPQEPAPVPSPPRAPTPPST-----PVPLPEKRRSILREPTFRWTSLTRELPPPPPA 624
+ V P P + TP +T P P P ++ P T++T P P
Sbjct: 4066 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-----PTPT 4120
Query: 625 PPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPA 684
P P+ P T++ P TP+ + +V TP P P
Sbjct: 4121 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPIT 4179
Query: 685 DDSPAEPEPRAVG-RTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQA 743
+ P P G +T + AP+ AE++ P S+ PQT PL
Sbjct: 4180 TTTTVTPTPTPTGTQTGPPTHTSTAPI------AELTTSNPPPESSTPQTSRSTSSPLTE 4233
Query: 744 LQTQL--LPQAL------PPPQPQ----------LQPPPSPQQMPPLEKARIAGVGS 782
T L LP A+ PP P L PPPS PP R GS
Sbjct: 4234 STTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS 4290
Score = 70.1 bits (170), Expect = 3e-11
Identities = 111/504 (22%), Positives = 147/504 (29%), Gaps = 120/504 (23%)
Query: 1821 PLDTDVLVPGAPERH-SPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGG 1879
P+D + P P SP L P + +PP + P +PS
Sbjct: 1391 PMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTT-----TPPPTTTPSPPITTT 1445
Query: 1880 VSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQL 1939
+ P +P P S T P P +PP + P P PP + +PP T+P
Sbjct: 1446 TTPPPTTTPSPPISTTTTPPPTTTP---SPPTTTPSPPTTTPSPPTTTTTTPPPTTTPS- 1501
Query: 1940 RVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLG 1999
PP T+ +T P S PP PSPP P
Sbjct: 1502 --PPTTTPIT--PPASTTTLPPTTTPSPPTTTTTTP------------------------ 1533
Query: 2000 TEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIE 2059
+ S PT+ I P + + P P+ TP P
Sbjct: 1534 ----------------------PPTTTPSPPTTTPITPPTSTTTLP---PTTTPSPPPTT 1568
Query: 2060 QLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLK 2119
T S T PS P + PP PS
Sbjct: 1569 TTTPPPTTTPSPPTT--------TTPSPPTITTT---------TPPPTTTPS-------- 1603
Query: 2120 NLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGP 2179
P + P+PP P T P PT T P P + P
Sbjct: 1604 ----PPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLP--PTTT----PSPPPTTTTTPPP 1653
Query: 2180 --APEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPG 2237
P PP T + PPP P P T +P+ PT+ P
Sbjct: 1654 TTTPSPPTTTTPSPPITT-------------TTTPPPTTTPSSPITTTPSPPTTTMTTPS 1700
Query: 2238 P-LLGVLPVVGVVRPA----PPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSG--RSPP 2290
P P+ P+ P PPP +T + SPP + +T S + P
Sbjct: 1701 PTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTP 1760
Query: 2291 APPPYKAPRLDEDGEASEDTPQVP 2314
PP P + TP VP
Sbjct: 1761 LPPSITPPTFSPFSTTTPTTPCVP 1784
Score = 70.1 bits (170), Expect = 3e-11
Identities = 84/383 (21%), Positives = 117/383 (30%), Gaps = 22/383 (5%)
Query: 392 PAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQE 451
P + P T P+P P T+ P P +P +P P
Sbjct: 2120 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2179
Query: 452 EQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTP-STATGGPPEDS 510
+P P T + P TP P GT PT TP +T T P +
Sbjct: 2180 TTTVTPTPTPTGTQT-----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2234
Query: 511 PTVAPKSTTFLKNIRQFIMPVVSARSSRV-IKTPRRFMDEDPPKPPKVEVSPVLRPPITT 569
PT TT + P + ++ TP P P PITT
Sbjct: 2235 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2294
Query: 570 SPPVPQEPAPVPSPPRAPTPPS-----TPVPLPEKRRSILREPTFRWTSLTRELPPPPPA 624
+ V P P + TP + TP P P ++ P T++T P P
Sbjct: 2295 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-----PTPT 2349
Query: 625 PPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPA 684
P P+ P T++ P TP+ + +V TP P P
Sbjct: 2350 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPIT 2408
Query: 685 DDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQAL 744
+ P P G + P TT V +P G + P T + P
Sbjct: 2409 TTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2465
Query: 745 QTQLLPQALP-PPQPQLQPPPSP 766
P P + P P+P
Sbjct: 2466 TGTQTPTTTPITTTTTVTPTPTP 2488
Score = 70.1 bits (170), Expect = 3e-11
Identities = 84/383 (21%), Positives = 117/383 (30%), Gaps = 22/383 (5%)
Query: 392 PAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQE 451
P + P T P+P P T+ P P +P +P P
Sbjct: 2396 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2455
Query: 452 EQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTP-STATGGPPEDS 510
+P P T + P TP P GT PT TP +T T P +
Sbjct: 2456 TTTVTPTPTPTGTQT-----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2510
Query: 511 PTVAPKSTTFLKNIRQFIMPVVSARSSRV-IKTPRRFMDEDPPKPPKVEVSPVLRPPITT 569
PT TT + P + ++ TP P P PITT
Sbjct: 2511 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2570
Query: 570 SPPVPQEPAPVPSPPRAPTPPS-----TPVPLPEKRRSILREPTFRWTSLTRELPPPPPA 624
+ V P P + TP + TP P P ++ P T++T P P
Sbjct: 2571 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-----PTPT 2625
Query: 625 PPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPA 684
P P+ P T++ P TP+ + +V TP P P
Sbjct: 2626 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPIT 2684
Query: 685 DDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQAL 744
+ P P G + P TT V +P G + P T + P
Sbjct: 2685 TTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2741
Query: 745 QTQLLPQALP-PPQPQLQPPPSP 766
P P + P P+P
Sbjct: 2742 TGTQTPTTTPITTTTTVTPTPTP 2764
Score = 70.1 bits (170), Expect = 3e-11
Identities = 84/383 (21%), Positives = 117/383 (30%), Gaps = 22/383 (5%)
Query: 392 PAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQE 451
P + P T P+P P T+ P P +P +P P
Sbjct: 2672 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2731
Query: 452 EQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTP-STATGGPPEDS 510
+P P T + P TP P GT PT TP +T T P +
Sbjct: 2732 TTTVTPTPTPTGTQT-----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2786
Query: 511 PTVAPKSTTFLKNIRQFIMPVVSARSSRV-IKTPRRFMDEDPPKPPKVEVSPVLRPPITT 569
PT TT + P + ++ TP P P PITT
Sbjct: 2787 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2846
Query: 570 SPPVPQEPAPVPSPPRAPTPPS-----TPVPLPEKRRSILREPTFRWTSLTRELPPPPPA 624
+ V P P + TP + TP P P ++ P T++T P P
Sbjct: 2847 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-----PTPT 2901
Query: 625 PPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPA 684
P P+ P T++ P TP+ + +V TP P P
Sbjct: 2902 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPIT 2960
Query: 685 DDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQAL 744
+ P P G + P TT V +P G + P T + P
Sbjct: 2961 TTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3017
Query: 745 QTQLLPQALP-PPQPQLQPPPSP 766
P P + P P+P
Sbjct: 3018 TGTQTPTTTPITTTTTVTPTPTP 3040
Score = 70.1 bits (170), Expect = 3e-11
Identities = 84/383 (21%), Positives = 117/383 (30%), Gaps = 22/383 (5%)
Query: 392 PAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQE 451
P + P T P+P P T+ P P +P +P P
Sbjct: 2948 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3007
Query: 452 EQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTP-STATGGPPEDS 510
+P P T + P TP P GT PT TP +T T P +
Sbjct: 3008 TTTVTPTPTPTGTQT-----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3062
Query: 511 PTVAPKSTTFLKNIRQFIMPVVSARSSRV-IKTPRRFMDEDPPKPPKVEVSPVLRPPITT 569
PT TT + P + ++ TP P P PITT
Sbjct: 3063 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3122
Query: 570 SPPVPQEPAPVPSPPRAPTPPS-----TPVPLPEKRRSILREPTFRWTSLTRELPPPPPA 624
+ V P P + TP + TP P P ++ P T++T P P
Sbjct: 3123 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-----PTPT 3177
Query: 625 PPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPA 684
P P+ P T++ P TP+ + +V TP P P
Sbjct: 3178 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPIT 3236
Query: 685 DDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQAL 744
+ P P G + P TT V +P G + P T + P
Sbjct: 3237 TTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3293
Query: 745 QTQLLPQALP-PPQPQLQPPPSP 766
P P + P P+P
Sbjct: 3294 TGTQTPTTTPITTTTTVTPTPTP 3316
Score = 70.1 bits (170), Expect = 3e-11
Identities = 84/383 (21%), Positives = 117/383 (30%), Gaps = 22/383 (5%)
Query: 392 PAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQE 451
P + P T P+P P T+ P P +P +P P
Sbjct: 3224 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3283
Query: 452 EQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTP-STATGGPPEDS 510
+P P T + P TP P GT PT TP +T T P +
Sbjct: 3284 TTTVTPTPTPTGTQT-----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3338
Query: 511 PTVAPKSTTFLKNIRQFIMPVVSARSSRV-IKTPRRFMDEDPPKPPKVEVSPVLRPPITT 569
PT TT + P + ++ TP P P PITT
Sbjct: 3339 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3398
Query: 570 SPPVPQEPAPVPSPPRAPTPPS-----TPVPLPEKRRSILREPTFRWTSLTRELPPPPPA 624
+ V P P + TP + TP P P ++ P T++T P P
Sbjct: 3399 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-----PTPT 3453
Query: 625 PPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPA 684
P P+ P T++ P TP+ + +V TP P P
Sbjct: 3454 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPIT 3512
Query: 685 DDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQAL 744
+ P P G + P TT V +P G + P T + P
Sbjct: 3513 TTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3569
Query: 745 QTQLLPQALP-PPQPQLQPPPSP 766
P P + P P+P
Sbjct: 3570 TGTQTPTTTPITTTTTVTPTPTP 3592
Score = 70.1 bits (170), Expect = 3e-11
Identities = 84/383 (21%), Positives = 117/383 (30%), Gaps = 22/383 (5%)
Query: 392 PAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQE 451
P + P T P+P P T+ P P +P +P P
Sbjct: 3500 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3559
Query: 452 EQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTP-STATGGPPEDS 510
+P P T + P TP P GT PT TP +T T P +
Sbjct: 3560 TTTVTPTPTPTGTQT-----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3614
Query: 511 PTVAPKSTTFLKNIRQFIMPVVSARSSRV-IKTPRRFMDEDPPKPPKVEVSPVLRPPITT 569
PT TT + P + ++ TP P P PITT
Sbjct: 3615 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3674
Query: 570 SPPVPQEPAPVPSPPRAPTPPS-----TPVPLPEKRRSILREPTFRWTSLTRELPPPPPA 624
+ V P P + TP + TP P P ++ P T++T P P
Sbjct: 3675 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-----PTPT 3729
Query: 625 PPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPA 684
P P+ P T++ P TP+ + +V TP P P
Sbjct: 3730 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPIT 3788
Query: 685 DDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQAL 744
+ P P G + P TT V +P G + P T + P
Sbjct: 3789 TTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3845
Query: 745 QTQLLPQALP-PPQPQLQPPPSP 766
P P + P P+P
Sbjct: 3846 TGTQTPTTTPITTTTTVTPTPTP 3868
Score = 70.1 bits (170), Expect = 3e-11
Identities = 84/383 (21%), Positives = 117/383 (30%), Gaps = 22/383 (5%)
Query: 392 PAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQE 451
P + P T P+P P T+ P P +P +P P
Sbjct: 3776 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3835
Query: 452 EQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTP-STATGGPPEDS 510
+P P T + P TP P GT PT TP +T T P +
Sbjct: 3836 TTTVTPTPTPTGTQT-----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3890
Query: 511 PTVAPKSTTFLKNIRQFIMPVVSARSSRV-IKTPRRFMDEDPPKPPKVEVSPVLRPPITT 569
PT TT + P + ++ TP P P PITT
Sbjct: 3891 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3950
Query: 570 SPPVPQEPAPVPSPPRAPTPPS-----TPVPLPEKRRSILREPTFRWTSLTRELPPPPPA 624
+ V P P + TP + TP P P ++ P T++T P P
Sbjct: 3951 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-----PTPT 4005
Query: 625 PPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPA 684
P P+ P T++ P TP+ + +V TP P P
Sbjct: 4006 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPIT 4064
Query: 685 DDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQAL 744
+ P P G + P TT V +P G + P T + P
Sbjct: 4065 TTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 4121
Query: 745 QTQLLPQALP-PPQPQLQPPPSP 766
P P + P P+P
Sbjct: 4122 TGTQTPTTTPITTTTTVTPTPTP 4144
Score = 69.7 bits (169), Expect = 4e-11
Identities = 91/384 (23%), Positives = 123/384 (32%), Gaps = 39/384 (10%)
Query: 392 PAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQE 451
P + P T P+P P T+ P P +P +P P
Sbjct: 3960 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 4019
Query: 452 EQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTP-STATGGPPEDS 510
+P P T + P TP P GT PT TP +T T P +
Sbjct: 4020 TTTVTPTPTPTGTQT-----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 4074
Query: 511 PTVAPKSTTFLKNIRQFIMPVVSARSSRV-IKTPRRFMDEDPPKPPKVEVSPVLRPPITT 569
PT TT + P + ++ TP P P PITT
Sbjct: 4075 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 4134
Query: 570 SPPVPQEPAPVPSPPRAPTPPST-----PVPLPEKRRSILREPTFRWTSLTRELPPPPP- 623
+ V P P + TP +T P P P ++ P T++T P P P
Sbjct: 4135 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT---PTPTPT 4191
Query: 624 ---APPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVL--TPPPLGAPEAPE 678
PP + P A T+S P PQ + S + + L T PP A E
Sbjct: 4192 GTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPP--AIEMTS 4249
Query: 679 PEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLL 738
PP +P P + G T ++ P SP G P + G T +
Sbjct: 4250 TAPP---STPTAPTTTSGGHT-----------LSPPPSTTTSPPGTP--TRGTTTGSSSA 4293
Query: 739 QPLQALQTQLLPQALPPPQPQLQP 762
+QT P P P P
Sbjct: 4294 PTPSTVQTTTTSAWTPTPTPLSTP 4317
Score = 65.9 bits (159), Expect = 5e-10
Identities = 83/373 (22%), Positives = 117/373 (31%), Gaps = 25/373 (6%)
Query: 405 PLTPPAPSPPPPLPPPSTSPPP-PLCPPPPPPVSPPPLP--SPPPPPAQEEQEESPPPVV 461
P+T P P P + +P P+ +P P +P P +P P
Sbjct: 2383 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2442
Query: 462 PATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTP-STATGGPPEDSPTVAPKSTTF 520
T + P TP P GT PT TP +T T P +PT TT
Sbjct: 2443 TGTQT-----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2497
Query: 521 LKNIRQFIMPVVSARSSRV-IKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAP 579
+ P + ++ TP P P PITT+ V P P
Sbjct: 2498 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2557
Query: 580 VPSPPRAPTPPS-----TPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPP 634
+ TP + TP P P ++ P T++T P P P P+
Sbjct: 2558 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-----PTPTPTGTQTPTTT 2612
Query: 635 PAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPR 694
P T++ P TP+ + +V TP P P + P P
Sbjct: 2613 PITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPT 2671
Query: 695 AVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALP 754
G + P TT V +P G + P T + P P P
Sbjct: 2672 PTGTQTPTTTP---ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2728
Query: 755 -PPQPQLQPPPSP 766
+ P P+P
Sbjct: 2729 ITTTTTVTPTPTP 2741
Score = 65.9 bits (159), Expect = 5e-10
Identities = 83/373 (22%), Positives = 117/373 (31%), Gaps = 25/373 (6%)
Query: 405 PLTPPAPSPPPPLPPPSTSPPP-PLCPPPPPPVSPPPLP--SPPPPPAQEEQEESPPPVV 461
P+T P P P + +P P+ +P P +P P +P P
Sbjct: 2659 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2718
Query: 462 PATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTP-STATGGPPEDSPTVAPKSTTF 520
T + P TP P GT PT TP +T T P +PT TT
Sbjct: 2719 TGTQT-----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2773
Query: 521 LKNIRQFIMPVVSARSSRV-IKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAP 579
+ P + ++ TP P P PITT+ V P P
Sbjct: 2774 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2833
Query: 580 VPSPPRAPTPPS-----TPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPP 634
+ TP + TP P P ++ P T++T P P P P+
Sbjct: 2834 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-----PTPTPTGTQTPTTT 2888
Query: 635 PAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPR 694
P T++ P TP+ + +V TP P P + P P
Sbjct: 2889 PITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPT 2947
Query: 695 AVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALP 754
G + P TT V +P G + P T + P P P
Sbjct: 2948 PTGTQTPTTTP---ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3004
Query: 755 -PPQPQLQPPPSP 766
+ P P+P
Sbjct: 3005 ITTTTTVTPTPTP 3017
Score = 65.9 bits (159), Expect = 5e-10
Identities = 83/373 (22%), Positives = 117/373 (31%), Gaps = 25/373 (6%)
Query: 405 PLTPPAPSPPPPLPPPSTSPPP-PLCPPPPPPVSPPPLP--SPPPPPAQEEQEESPPPVV 461
P+T P P P + +P P+ +P P +P P +P P
Sbjct: 2935 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2994
Query: 462 PATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTP-STATGGPPEDSPTVAPKSTTF 520
T + P TP P GT PT TP +T T P +PT TT
Sbjct: 2995 TGTQT-----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3049
Query: 521 LKNIRQFIMPVVSARSSRV-IKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAP 579
+ P + ++ TP P P PITT+ V P P
Sbjct: 3050 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3109
Query: 580 VPSPPRAPTPPS-----TPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPP 634
+ TP + TP P P ++ P T++T P P P P+
Sbjct: 3110 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-----PTPTPTGTQTPTTT 3164
Query: 635 PAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPR 694
P T++ P TP+ + +V TP P P + P P
Sbjct: 3165 PITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPT 3223
Query: 695 AVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALP 754
G + P TT V +P G + P T + P P P
Sbjct: 3224 PTGTQTPTTTP---ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3280
Query: 755 -PPQPQLQPPPSP 766
+ P P+P
Sbjct: 3281 ITTTTTVTPTPTP 3293
Score = 65.9 bits (159), Expect = 5e-10
Identities = 83/373 (22%), Positives = 117/373 (31%), Gaps = 25/373 (6%)
Query: 405 PLTPPAPSPPPPLPPPSTSPPP-PLCPPPPPPVSPPPLP--SPPPPPAQEEQEESPPPVV 461
P+T P P P + +P P+ +P P +P P +P P
Sbjct: 3211 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3270
Query: 462 PATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTP-STATGGPPEDSPTVAPKSTTF 520
T + P TP P GT PT TP +T T P +PT TT
Sbjct: 3271 TGTQT-----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3325
Query: 521 LKNIRQFIMPVVSARSSRV-IKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAP 579
+ P + ++ TP P P PITT+ V P P
Sbjct: 3326 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3385
Query: 580 VPSPPRAPTPPS-----TPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPP 634
+ TP + TP P P ++ P T++T P P P P+
Sbjct: 3386 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-----PTPTPTGTQTPTTT 3440
Query: 635 PAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPR 694
P T++ P TP+ + +V TP P P + P P
Sbjct: 3441 PITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPT 3499
Query: 695 AVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALP 754
G + P TT V +P G + P T + P P P
Sbjct: 3500 PTGTQTPTTTP---ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3556
Query: 755 -PPQPQLQPPPSP 766
+ P P+P
Sbjct: 3557 ITTTTTVTPTPTP 3569
Score = 65.9 bits (159), Expect = 5e-10
Identities = 83/373 (22%), Positives = 117/373 (31%), Gaps = 25/373 (6%)
Query: 405 PLTPPAPSPPPPLPPPSTSPPP-PLCPPPPPPVSPPPLP--SPPPPPAQEEQEESPPPVV 461
P+T P P P + +P P+ +P P +P P +P P
Sbjct: 3487 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3546
Query: 462 PATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTP-STATGGPPEDSPTVAPKSTTF 520
T + P TP P GT PT TP +T T P +PT TT
Sbjct: 3547 TGTQT-----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3601
Query: 521 LKNIRQFIMPVVSARSSRV-IKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAP 579
+ P + ++ TP P P PITT+ V P P
Sbjct: 3602 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3661
Query: 580 VPSPPRAPTPPS-----TPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPP 634
+ TP + TP P P ++ P T++T P P P P+
Sbjct: 3662 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-----PTPTPTGTQTPTTT 3716
Query: 635 PAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPR 694
P T++ P TP+ + +V TP P P + P P
Sbjct: 3717 PITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPT 3775
Query: 695 AVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALP 754
G + P TT V +P G + P T + P P P
Sbjct: 3776 PTGTQTPTTTP---ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3832
Query: 755 -PPQPQLQPPPSP 766
+ P P+P
Sbjct: 3833 ITTTTTVTPTPTP 3845
Score = 65.9 bits (159), Expect = 5e-10
Identities = 83/373 (22%), Positives = 117/373 (31%), Gaps = 25/373 (6%)
Query: 405 PLTPPAPSPPPPLPPPSTSPPP-PLCPPPPPPVSPPPLP--SPPPPPAQEEQEESPPPVV 461
P+T P P P + +P P+ +P P +P P +P P
Sbjct: 3763 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3822
Query: 462 PATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTP-STATGGPPEDSPTVAPKSTTF 520
T + P TP P GT PT TP +T T P +PT TT
Sbjct: 3823 TGTQT-----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3877
Query: 521 LKNIRQFIMPVVSARSSRV-IKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAP 579
+ P + ++ TP P P PITT+ V P P
Sbjct: 3878 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3937
Query: 580 VPSPPRAPTPPS-----TPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPP 634
+ TP + TP P P ++ P T++T P P P P+
Sbjct: 3938 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-----PTPTPTGTQTPTTT 3992
Query: 635 PAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPR 694
P T++ P TP+ + +V TP P P + P P
Sbjct: 3993 PITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPT 4051
Query: 695 AVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALP 754
G + P TT V +P G + P T + P P P
Sbjct: 4052 PTGTQTPTTTP---ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4108
Query: 755 -PPQPQLQPPPSP 766
+ P P+P
Sbjct: 4109 ITTTTTVTPTPTP 4121
Score = 63.9 bits (154), Expect = 2e-09
Identities = 95/448 (21%), Positives = 129/448 (28%), Gaps = 54/448 (12%)
Query: 1868 PNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFP----APPRRSRRPSP---LA 1920
P +PS P + P +P P++ T P P P P + PSP
Sbjct: 1402 PTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTT 1461
Query: 1921 PRPPPSRWASPPLKT-SPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPED--LGPDF 1977
PPP+ SPP T SP P P + T P + +PP P PP L P
Sbjct: 1462 TTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTT 1521
Query: 1978 EDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHF 2037
+ + S T P ++ P PT+
Sbjct: 1522 TPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSP--------PPTTTTTPP 1573
Query: 2038 PVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLG 2097
P T S P + TP P I T S T PS P +
Sbjct: 1574 PTTTPSPP---TTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPP--TTTPITP 1628
Query: 2098 AAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASP- 2156
PP PS P P + P P S P T P
Sbjct: 1629 PTSTTTLPPTTTPSP-----------PPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPP 1677
Query: 2157 -ADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPV 2215
P+ P P + + P P P T+ + P PPP
Sbjct: 1678 TTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTT-----------TTPSSTTTPSPPPT 1726
Query: 2216 KQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQA 2275
T++ +PT+ PP + LP P P PP + P S
Sbjct: 1727 -------TMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPT 1779
Query: 2276 IRVKRVSTFSGRSPPAPPPYKAPRLDED 2303
+ ++G P + P D +
Sbjct: 1780 TPCVPLCNWTGWLDSGKPNFHKPGGDTE 1807
Score = 63.5 bits (153), Expect = 3e-09
Identities = 78/349 (22%), Positives = 109/349 (31%), Gaps = 25/349 (7%)
Query: 429 CPPPPPPVSPPPLPSPPPP---PAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAA 485
C P ++ +P PP P +P P T + P TP
Sbjct: 1878 CVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQT-----PTTTPITTTTTVTP 1932
Query: 486 RAGPEGTSPPTPTP-STATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRV-IKTP 543
P GT PT TP +T T P +PT TT + P + ++ TP
Sbjct: 1933 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 1992
Query: 544 RRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPS-----TPVPLPE 598
P P PITT+ V P P + TP + TP P P
Sbjct: 1993 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2052
Query: 599 KRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAH 658
++ P T++T P P P P+ P T++ P TP+
Sbjct: 2053 GTQTPTTTPITTTTTVT-----PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2107
Query: 659 LKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAE 718
+ +V TP P P + P P G + P TT V
Sbjct: 2108 ITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPT 2163
Query: 719 VSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALP-PPQPQLQPPPSP 766
+P G + P T + P P P + P P+P
Sbjct: 2164 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2212
Score = 61.2 bits (147), Expect = 1e-08
Identities = 46/176 (26%), Positives = 60/176 (34%), Gaps = 16/176 (9%)
Query: 1803 TIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFSG 1862
T +P P++ P PP T + P + P PP + P P
Sbjct: 1489 TTTTTPPPTTTP----SPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTP----- 1539
Query: 1863 ARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPR 1922
P +P P + P +P P + T P P P S P+
Sbjct: 1540 ---SPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPS-PPTITTTT 1595
Query: 1923 PPPSRWASPPLKTS---PQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGP 1975
PPP+ SPP T+ P P P + PTS PP PSPPP P
Sbjct: 1596 PPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTP 1651
Score = 61.2 bits (147), Expect = 1e-08
Identities = 88/400 (22%), Positives = 123/400 (30%), Gaps = 46/400 (11%)
Query: 402 PPPPLTPP-------APSPPPP-LPPPSTSP---PPPLCPPPPPPVSPPPLPSP------ 444
P PP T P P+P P P+T+P + P P P + P +P
Sbjct: 1893 PTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 1952
Query: 445 --PPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTP--- 499
P P Q + P+ T P T +Q T PTPT
Sbjct: 1953 VTPTPTPTGTQTPTTTPITTTTTVTPTPTP--TGTQTPTTTPITTTTTVTPTPTPTGTQT 2010
Query: 500 ------STATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRV-IKTPRRFMDEDPP 552
+T T P +PT TT + P + ++ TP P
Sbjct: 2011 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2070
Query: 553 KPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPS-----TPVPLPEKRRSILREP 607
P PITT+ V P P + TP + TP P P ++ P
Sbjct: 2071 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2130
Query: 608 TFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLT 667
T++T P P P P+ P T++ P TP+ + +V T
Sbjct: 2131 ITTTTTVT-----PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-T 2184
Query: 668 PPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPAL 727
P P P + P P G + P TT V +P G
Sbjct: 2185 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPTPTGTQTP 2241
Query: 728 SNGPQTQAQLLQPLQALQTQLLPQALP-PPQPQLQPPPSP 766
+ P T + P P P + P P+P
Sbjct: 2242 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2281
Score = 57.8 bits (138), Expect = 1e-07
Identities = 83/401 (20%), Positives = 125/401 (31%), Gaps = 51/401 (12%)
Query: 402 PPPP---LTPPAPSPPPPLPPPSTSPPPPLCPPPPPPV-----SPPPLPSPPP------P 447
P PP +T P+P+ P P +T+ P P PPP SP PSPP P
Sbjct: 1689 PSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLP 1748
Query: 448 PAQEEQEES----PPPVVPATCSRKRGRPPLTPSQRAEREAA---RAGPEGTSPPTPTPS 500
P + PP + P T S P TP P P T
Sbjct: 1749 PTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTEL 1808
Query: 501 TATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPP----- 555
P + ++ ++T + +P+ + V + ++ + P
Sbjct: 1809 IGDVCGPGWAANISCRATMYPD------VPIGQLGQTVVCDVSVGLICKNEDQKPGGVIP 1862
Query: 556 ---------KVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILRE 606
V+ + P T + + P P + P T TP P P ++
Sbjct: 1863 MAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTT 1922
Query: 607 PTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVL 666
P T++T P P P P+ P T++ P TP+ + +V
Sbjct: 1923 PITTTTTVT-----PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV- 1976
Query: 667 TPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPA 726
TP P P + P P G + P TT V +P G
Sbjct: 1977 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPTPTGTQT 2033
Query: 727 LSNGPQTQAQLLQPLQALQTQLLPQALP-PPQPQLQPPPSP 766
+ P T + P P P + P P+P
Sbjct: 2034 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2074
Score = 55.5 bits (132), Expect = 7e-07
Identities = 99/473 (20%), Positives = 138/473 (29%), Gaps = 90/473 (19%)
Query: 1805 VHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFSGAR 1864
+ +P+P + P PP T L P PP P + +PP +
Sbjct: 1396 ITTPSPPTTTPS--PPPTSTTTLPPTTTPSPPTTTTTTPP--PTTTPSPP-----ITTTT 1446
Query: 1865 IKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRR-PSPLAPRP 1923
P +PS P+ + P + SP + T PT P+PP + P P
Sbjct: 1447 TPPPTTTPSP-PISTTTTPPPTTTPSPPTTTPSPPTTT----PSPPTTTTTTPPPTTTPS 1501
Query: 1924 PPSRW-ASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEV 1982
PP+ +PP T+ +PP T T PT+ PP P +P PP
Sbjct: 1502 PPTTTPITPPASTT---TLPPTT---TPSPPTTTTTTPP-PTTTPSPPT----------- 1543
Query: 1983 VSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVV 2042
T P ++ P ++ PT+
Sbjct: 1544 -----------------TTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTT---------- 1576
Query: 2043 SAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDR 2102
P + TP P I T S T PS P +
Sbjct: 1577 -TPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPP--TTTPITPPTSTT 1633
Query: 2103 ARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASP--ADPT 2160
PP PS P P + P P S P T P P+
Sbjct: 1634 TLPPTTTPSP-----------PPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPS 1682
Query: 2161 RTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPL 2220
P P + + P P P T+ + P PPP
Sbjct: 1683 SPITTTPSPPTTTMTTPSPTTTPSSPITTT-----------TTPSSTTTPSPPPTTMTTP 1731
Query: 2221 PPTISPTAPTS--WTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASP 2271
PT +P+ PT+ TLPP L + PP P + + P P
Sbjct: 1732 SPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVP 1784
Score = 55.5 bits (132), Expect = 7e-07
Identities = 103/456 (22%), Positives = 142/456 (31%), Gaps = 92/456 (20%)
Query: 1803 TIVHSPAPSSE----PPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPR 1858
T SP P+S P PP T P PI P P + + PP
Sbjct: 1403 TTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTP--PPTTTPSPP--- 1457
Query: 1859 SFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPA------PPRR 1912
S P +PS P P +P P++ T P P P P
Sbjct: 1458 -ISTTTTPPPTTTPS--PPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPAST 1514
Query: 1913 SRRPSPLAPRPPPSRWASPPLKTSPQ----LRVPPPTSVVTALTPTSGELAPPGPAPSPP 1968
+ P P PP + +PP T+P + PPTS T L PT+ P P +
Sbjct: 1515 TTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTT-LPPTT--TPSPPPTTTTT 1571
Query: 1969 PPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEES 2028
PP P S ++ T P + ++ P + S
Sbjct: 1572 PPPTTTPSPPTTTTPS---------PPTITTTTPPPTTTPSPPTTTTTTPPP---TTTPS 1619
Query: 2029 SPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGP 2088
PT+ I P + + P P+ TP P T S T PS P
Sbjct: 1620 PPTTTPITPPTSTTTLP---PTTTPSPPPTTTTTPPPTTTPSPPTT--------TTPSPP 1668
Query: 2089 GVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQP 2148
PP PS + + P+PP + P
Sbjct: 1669 ---------ITTTTTPPPTTTPSSPI--------------------TTTPSPPTTTMTTP 1699
Query: 2149 SQGLTASPADP-----TRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVK 2203
S T +P+ P T + P P + + P P P T+ + L
Sbjct: 1700 SP--TTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTT----MTTLPPTTTS 1753
Query: 2204 MAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPL 2239
P+PP + PPT SP + T+ T P PL
Sbjct: 1754 SPLTTTPLPPSI----TPPTFSPFSTTTPTTPCVPL 1785
Score = 51.2 bits (121), Expect = 1e-05
Identities = 53/247 (21%), Positives = 72/247 (29%), Gaps = 50/247 (20%)
Query: 2138 PAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKL 2197
P+PP++ + P T SP T + +P + P P P T+
Sbjct: 1454 PSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTT------- 1506
Query: 2198 GQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGV--------- 2248
P+ PP LPPT +P+ PT+ T P P P
Sbjct: 1507 ------------PITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTT 1554
Query: 2249 -VRPAPPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEAS 2307
+ P P PPP T +P T + +PP P
Sbjct: 1555 TLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPP 1614
Query: 2308 EDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLPLPEDGPP 2367
TP P + + PT L P SP P +P PP
Sbjct: 1615 TTTPSPP-------TTTPITPPTSTTTL------PPTTTPSPPPTTTTTP--------PP 1653
Query: 2368 QVPDGPP 2374
PP
Sbjct: 1654 TTTPSPP 1660
Score = 42.4 bits (98), Expect = 0.006
Identities = 87/470 (18%), Positives = 129/470 (27%), Gaps = 68/470 (14%)
Query: 1803 TIVHSPAPSSEPPGGEDP---PLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRS 1859
T + P+ P G + P P+ T V P P+ + P P P
Sbjct: 3880 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3939
Query: 1860 FSGARIKVPNYSPSRRPLGGVS-FGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSP 1918
+P+ P+ + P P+P + T T P P +
Sbjct: 3940 ---------TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3990
Query: 1919 LAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGP-----------APSP 1967
P + P T Q P + T +TPT P P+P
Sbjct: 3991 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 4050
Query: 1968 PPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEE 2027
P P + + ++ T P P +
Sbjct: 4051 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT---------PTPTPTGT 4101
Query: 2028 SSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSG 2087
+PT+ I TV P + TP I T + P G TP +
Sbjct: 4102 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTT 4153
Query: 2088 PGVVRAGVLGA-AGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPP-------- 2138
P V + P P V G P S P
Sbjct: 4154 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSN 4213
Query: 2139 APPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLG 2198
PP ++ Q S+ ++ + T + LP P + + S P P P T+ G
Sbjct: 4214 PPPESSTPQTSRSTSSPLTESTTLLSTLP--PAIEMTSTAPPSTPTAPTTTS-------G 4264
Query: 2199 QVFVKMAGEGEPVPPPV---------KQPPLPPTISPTAPTSWTLPPGPL 2239
+ PP P P T+ T ++WT P PL
Sbjct: 4265 GHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPL 4314
Score = 36.2 bits (82), Expect = 0.45
Identities = 19/47 (40%), Positives = 20/47 (42%), Gaps = 5/47 (10%)
Query: 411 PSPPPPLPPPSTSPPPPLCPP-----PPPPVSPPPLPSPPPPPAQEE 452
PS P P P PS S P P P P P PP P PP + E
Sbjct: 4377 PSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQENE 4423
Score = 35.0 bits (79), Expect = 1.0
Identities = 42/167 (25%), Positives = 51/167 (30%), Gaps = 36/167 (21%)
Query: 382 EERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPL-PPPSTSPPPPLCPPPPPPV--SP 438
E + + PA E P P P S L PPPST+ PP P S
Sbjct: 4233 ESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSS 4292
Query: 439 PPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPP----------LTPSQRAEREAARAG 488
P PS +P P+ + R G P L + A E G
Sbjct: 4293 APTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNG 4352
Query: 489 PEG-----------------------TSPPTPTPSTATGGPPEDSPT 512
G T PTPTPS +T P + S T
Sbjct: 4353 TYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSST 4399
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 121 bits (304), Expect = 8e-27
Identities = 183/717 (25%), Positives = 240/717 (33%), Gaps = 157/717 (21%)
Query: 138 RSALRSQRGRAPR----GRGRKHKTTPLPPPRLADVAPTPPKTPARKRGEE-----GTER 188
RSA S R A R GRG + PP + + +P P +P R G G +
Sbjct: 81 RSAGTSSRNPASRPPASGRGER-----APPAK--NTSPGPVSSPGRASGTTRPGPLGQKG 133
Query: 189 MVQALTELLRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIP 248
+ + E + R +A +AP+ A R + G PG P+ R+ +A A V +P
Sbjct: 134 LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA---AGTEVGLP 190
Query: 249 KPEPP----PPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGGLPFV 304
+P P PP + S P P RR GGGL
Sbjct: 191 RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA-------------GGGLQ-- 235
Query: 305 IKFVSRAKKVKMGQLSLGLESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQE--QKLD 362
+ SR+ LS SG P R P K + Q L
Sbjct: 236 -RPASRSLSSSATPLSSPARSG-------------PSARGTPRAPAHPSQPKPKGLQALR 281
Query: 363 DEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPS------PPPP 416
+ ++ G P+A + P P TP + S P P
Sbjct: 282 PPQVTPPRKDAAPALGPLSSSPLATPS--PSAALQSQAPPTLPATPHSSSLTCQLATPLP 339
Query: 417 LPPPSTSPPPPLCPPPPPPVSPP-------------------------PLPSPPP--PPA 449
L PPS S PP L P PP +PP PL +PPP PPA
Sbjct: 340 LAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPA 399
Query: 450 QEEQEESPPPVVPATCSRKRGRPPL----TPSQRAEREAARAGPEGTSPPTPTPSTATGG 505
PP PA+ PPL TPS +A A + P P+P
Sbjct: 400 LALPPLQAPPSPPAS-------PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF 452
Query: 506 PPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLR- 564
P SP V+P +T + P + S P PP+ P +P L+
Sbjct: 453 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL 512
Query: 565 -------PPITTSPPVPQEPAPVPS-PPRAPTPPSTPVPL------PEKRRSILREPTFR 610
PP +PP+ P+P S P +AP PS +P+ P + +L P
Sbjct: 513 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL- 571
Query: 611 WTSLTRELPPPPPAPPPPPAPSPPPAPA--TSSRRPLLL------------RAPQFTPSE 656
++PP PPA P AP PP P TS P L R+P T S
Sbjct: 572 ------QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSG 625
Query: 657 AHLKIYESVLTPPPL------GAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLP-RFAP 709
L + S T P PE PP D A P A R L R AP
Sbjct: 626 PDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAP 685
Query: 710 VVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSP 766
P P A L +T+ P++ P L P PSP
Sbjct: 686 GAPLPWPPATGPGSADGLCTIYETEG--------------PESATPAPGALDPGPSP 728
Score = 102 bits (253), Expect = 7e-21
Identities = 174/683 (25%), Positives = 230/683 (33%), Gaps = 203/683 (29%)
Query: 395 EKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPL------------- 441
++++AK TP A +P +P PP P PPPPV+P L
Sbjct: 4 KRDKAKAGAAARTPAARAPG------LLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKP 57
Query: 442 -------------PSPPP------------------PPAQEEQEESPP-------PV--- 460
P P PPA E +PP PV
Sbjct: 58 LAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSP 117
Query: 461 ------------------VPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTP--- 499
+ A + RG+ P + A AR G +P TP+P
Sbjct: 118 GRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMA 177
Query: 500 --STATG---GPPEDSPTVAPKSTT----------------------------------- 519
S A G G P +P+ P+ T
Sbjct: 178 RRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRP 237
Query: 520 FLKNIRQFIMPVVS-ARSSRVIK-TPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEP 577
+++ P+ S ARS + TPR PKP ++ LRPP T P P
Sbjct: 238 ASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQ---ALRPPQVTPPRKDAAP 294
Query: 578 A--PVPSPPRAPTPPS------TPVPLPEKRRSILREPTFRWTSLTREL-------PPPP 622
A P+ S P A PS P LP S +SLT +L PP P
Sbjct: 295 ALGPLSSSPLATPSPSAALQSQAPPTLPATPHS---------SSLTCQLATPLPLAPPSP 345
Query: 623 PAPP-----PPPAPSPPPAPATSSRRPLL------LRAPQFTPSEAHLKIYESVLTPPPL 671
APP P P +PP TS P L L +P +P L PPL
Sbjct: 346 SAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPL 405
Query: 672 GAPEAPEPEP---PPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALS 728
AP +P P P A SP P AV HL F+P + PV+A SP +P +S
Sbjct: 406 QAPPSPPASPPLSPLATPSPQAPNALAV----HLLQAPFSPPPSPPVQAPFSPPASPPVS 461
Query: 729 NG--PQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPS---PQQMPPLEKAR-----IA 778
P +QA LQ P A PP P PPP P PPL+ A+
Sbjct: 462 PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPP 521
Query: 779 GVGSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAV--KQI 836
+ + PL + S +A +AS+P+SP A V +
Sbjct: 522 ALATPPLQALPSPPASFPGQAPF-----------SPSASLPMSPLATPPPQAPPVLAAPL 570
Query: 837 SDRGPVRSEDESVEAKRERPS-GPESPVQGPRIKHVCRHAAVALGQARAMVPEDVPRLSA 895
P +++A R P+ GP++ V GPR L A A P P S
Sbjct: 571 LQVPPSPPASPTLQAPRRPPTPGPDTSVSGPR-----------LTLALAPGPPPPPSRSP 619
Query: 896 LPLRDRQDLATEDTSSASETESV 918
DLA +S+ S E +
Sbjct: 620 SSTLSGPDLAGHSSSATSTPEEL 642
Score = 78.6 bits (192), Expect = 8e-14
Identities = 128/537 (23%), Positives = 177/537 (32%), Gaps = 69/537 (12%)
Query: 1784 RPWGPREEPAH-LEAAEENQTIVHSPAPSSEPP--GGEDPPLDTDVLVPGAPERHSPIQN 1840
RP P E P + +A E+ T SPA P GG P + P SP ++
Sbjct: 197 RPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP-LSSPARS 255
Query: 1841 LDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRP----LGGVSFGPLPSPGSPSSLTH 1896
A P P+ ++ P +P R+ LG +S PL +P ++L
Sbjct: 256 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQS 315
Query: 1897 HIPTVGDPDFPAPPRRSRRPSPLA---PRPPPSRWASPPLKTSPQLRVPPPTSVVTAL-- 1951
P P PA P S LA P PPS A P L+T P PP+ T+L
Sbjct: 316 QAP----PTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGS 371
Query: 1952 ---TPTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIV 2008
T L P +P PP P + + S + L P +
Sbjct: 372 PTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNAL 431
Query: 2009 AAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGT 2068
A + + S P S + P + ++P ++PSATP + L
Sbjct: 432 AVHLLQAPF----------SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV 481
Query: 2069 DSEAEAVQQPRGQGTPP-SGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDG 2127
A TPP P + A L A+PP P + L+ L P
Sbjct: 482 PPSPPASPPMSPSATPPPQAPPPLAAPPL----QLAKPPPQAPPALATPPLQALPSPPAS 537
Query: 2128 GAGPR----EESLPPAPPLANGSQPSQGLTAS--------PADPTRTFAWLPGAPG---- 2171
G SLP +P Q L A PA PT P PG
Sbjct: 538 FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTS 597
Query: 2172 ------VRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGE-------PVPPPVKQP 2218
L+ GP P P + +S + + G + E P P
Sbjct: 598 VSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASP 657
Query: 2219 PLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPP-----LTLVLSSGPAS 2270
P ++ P +W+ P P L G P PP P T+ + GP S
Sbjct: 658 PPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPES 714
Score = 75.1 bits (183), Expect = 9e-13
Identities = 73/267 (27%), Positives = 91/267 (34%), Gaps = 60/267 (22%)
Query: 402 PPPPLTPPAPSPP------PPLPPPSTSPPPPLCPPPPP-------PVSP------PPLP 442
PPP PP +PP PP PP+ + PP P PP P SP PL
Sbjct: 497 PPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 556
Query: 443 SPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTA 502
+PPP PPV+ A + PP +P+ +A R PPTP P T+
Sbjct: 557 TPPP---------QAPPVLAAPLLQVPPSPPASPTLQAPRR----------PPTPGPDTS 597
Query: 503 TGGP---------PEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPK 553
GP P P+ +P ST P ++ SS TP D
Sbjct: 598 VSGPRLTLALAPGPPPPPSRSPSST--------LSGPDLAGHSSSATSTPEELRGYDSGP 649
Query: 554 PPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTS 613
SP + P P P P P P+P P +
Sbjct: 650 EGGAAASPPPDAELAACHPAAWSRGPAP-PLAFRGAPGAPLPWP----PATGPGSADGLC 704
Query: 614 LTRELPPPPPAPPPPPAPSPPPAPATS 640
E P A P P A P P+P TS
Sbjct: 705 TIYETEGPESATPAPGALDPGPSPGTS 731
Score = 67.0 bits (162), Expect = 2e-10
Identities = 158/661 (23%), Positives = 213/661 (32%), Gaps = 184/661 (27%)
Query: 1810 PSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPP---PAPRSFSGARIK 1866
P+S PP G ER P +N P G A P P G RI
Sbjct: 90 PASRPPAS------------GRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS 137
Query: 1867 VPNY--------SPSRRPL--GGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSR-- 1914
+P R L G P+PG+PS PA RRSR
Sbjct: 138 AEETVARGKATEAPKRSALSAGARRDTSGPTPGTPS--------------PAMARRSRAA 183
Query: 1915 -------RPSPLA-PRPPP--------------SRWASPPLKTSPQ----LRVPPPTSVV 1948
RP+P A PRPP + SP + P L+ P S+
Sbjct: 184 GTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS 243
Query: 1949 TALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIV 2008
++ TP S A GP+ P P + + L + T P ++
Sbjct: 244 SSATPLSSP-ARSGPSARGTPRAPAHPSQPKPKGLQALRPPQV--------TPPRKDAAP 294
Query: 2009 AAGAMGSSH---GGPGDSSEEESSPTSRYIHFPVTVVSAP---------GLAPSATPGAP 2056
A G + SS P + + ++ PT P T S+ LAP + P
Sbjct: 295 ALGPLSSSPLATPSPSAALQSQAPPT-----LPATPHSSSLTCQLATPLPLAPPSPSAPP 349
Query: 2057 RIEQLDGVDDGTDSEAE-AVQQPRGQGT------PPSGPGVVRAGVLGAAGDRARPPEDL 2109
++ L S+A ++ P Q T PP P A PP
Sbjct: 350 SLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSP-------------LATPPPQA 396
Query: 2110 PSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTA----------SPADP 2159
P + L L P P + PP PLA S + A P+ P
Sbjct: 397 PPALA---LPPLQAP------PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP 447
Query: 2160 TRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPP 2219
+ P +P V + P+ PP A PP++ PP
Sbjct: 448 VQAPFSPPASPPVSPSATPPSQAPPSLAA------------------------PPLQVPP 483
Query: 2220 LPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPP----PPLTLVLSSGPASPPRQA 2275
PP P +P++ P P P + + +P P PP PPL L S PAS P QA
Sbjct: 484 SPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQ-ALPSPPASFPGQA 542
Query: 2276 IRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVL 2335
S SP A PP PQ P + + +V P +
Sbjct: 543 PFSPSASL--PMSPLATPP----------------PQAPPVLAAPLLQVPPSPPASPTLQ 584
Query: 2336 DLDRPGEPAGEESPGPLQERSPLLPLPEDGPPQVPDGPPDLLLES-QWHHYSGEASSSEE 2394
RP P + S + L P GPP P P L +S A+S+ E
Sbjct: 585 APRRPPTPGPDTSVSGPRLTLALAP----GPPPPPSRSPSSTLSGPDLAGHSSSATSTPE 640
Query: 2395 E 2395
E
Sbjct: 641 E 641
Score = 66.2 bits (160), Expect = 4e-10
Identities = 100/372 (26%), Positives = 131/372 (35%), Gaps = 69/372 (18%)
Query: 1807 SPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLR---------PDSGSA--PPP 1855
SP PS PP V P +P PPL+ P S SA PP
Sbjct: 441 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 500
Query: 1856 APRSFSGARIKVPNYSPSRRP-LGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSR 1914
AP + +++ P P L LPSP P P P S
Sbjct: 501 APPPLAAPPLQLAKPPPQAPPALATPPLQALPSP----------PASFPGQAPFSPSASL 550
Query: 1915 RPSPLAPRPPPSRWASPPLKTSPQLRVPP-----PTSVVTALTPTSG-ELAPPGP----- 1963
SPLA PP +PP+ +P L+VPP PT PT G + + GP
Sbjct: 551 PMSPLATPPP----QAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLA 606
Query: 1964 -APSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGD 2022
AP PPPP P S LS DL +S + P + +G G + P
Sbjct: 607 LAPGPPPPPSRSPS-------STLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPP 659
Query: 2023 SSEEES---SPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEA-EAVQQP 2078
+E + + SR P+ APG AP P A DG+ ++E E+
Sbjct: 660 DAELAACHPAAWSRGPAPPLAFRGAPG-APLPWPPATGPGSADGLCTIYETEGPESATPA 718
Query: 2079 RGQGTPPSGPGVV--RAGVLGAAGDRARPPED----------LPSEIVDFVLKNL----- 2121
G P PG +A AG +R P+ L + +V +L
Sbjct: 719 PGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAA 778
Query: 2122 --GGPGDGGAGP 2131
G G G GP
Sbjct: 779 AEGAAGGSGGGP 790
Score = 49.7 bits (117), Expect = 4e-05
Identities = 98/352 (27%), Positives = 123/352 (34%), Gaps = 66/352 (18%)
Query: 2070 SEAEAVQQPRGQGTPPSGPGVVRAG--VLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDG 2127
+ A + PR G+P P V A VLGAAG R P + + GG G G
Sbjct: 19 ARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKP----------LAERAGGIG-G 67
Query: 2128 GAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPA 2187
P ES P A P + S+ + P R AP + S GP P +
Sbjct: 68 ATIP--ESAPRAGPTRSAGTSSRNPASRPPASGRG----ERAPPAKNTSPGPVSSPGR-- 119
Query: 2188 TSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTA--PTSWTLP--PGPLL--- 2240
S LGQ ++++ E + P +S A TS P P P +
Sbjct: 120 ASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARR 179
Query: 2241 --GVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAP 2298
VG+ RPAP P P P PR K VS+ S S P P
Sbjct: 180 SRAAGTEVGLPRPAPSARPRP--------PTEGPR-----KSVSSASEHSTTEPSPAARR 226
Query: 2299 RLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGP--LQERS 2356
R G Q P S S + +P G P PA P P LQ
Sbjct: 227 RPSAGGGL-----QRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALR 281
Query: 2357 PLLPLPEDGPPQVPDGPPDLLLESQWHHYSGEASSSEEEPPSPDDK-ENQAP 2407
P P+ PP+ D P L G SSS PSP ++QAP
Sbjct: 282 P----PQVTPPR-KDAAPAL----------GPLSSSPLATPSPSAALQSQAP 318
Score = 34.7 bits (78), Expect = 1.3
Identities = 31/109 (28%), Positives = 39/109 (35%), Gaps = 14/109 (12%)
Query: 1033 DESPEASPGPPGPRRGAGAGGPREEVVAHPGPEEQDSL---LQRKSARRCVKQRPSYDIF 1089
+ +P A PGP G R PGP Q L + AR + P
Sbjct: 101 ERAPPAKNTSPGPVSSPG----RASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSAL 156
Query: 1090 EDSDDSEPGGP----PAP---RRRTPRENELPLPEPEEQSRPRKPTLQP 1131
+ GP P+P RR E+ LP P +RPR PT P
Sbjct: 157 SAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGP 205
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 119 bits (298), Expect = 4e-26
Identities = 172/677 (25%), Positives = 232/677 (34%), Gaps = 132/677 (19%)
Query: 134 PSSLRSALRSQRGRAPR-GRGRKHKTTPLPPPRLADVAPTPPKTPARKRGEE-----GTE 187
P S A ++ R P GRG + PP + + +P P +P R G G +
Sbjct: 71 PESAPRAGPTRTSRPPASGRGER-----APPAK--NTSPGPVSSPGRASGTTRPGPLGQK 123
Query: 188 RMVQALTELLRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVVAEAAVTI 247
+ + E + R +A +AP+ A R + G PG P+ R+ +A A V +
Sbjct: 124 GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA---AGTEVGL 180
Query: 248 PKPEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGGLPFVIKF 307
P+P P P EGP + + R GGGL +
Sbjct: 181 PRPAPSARPRPPT---------EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ---RP 228
Query: 308 VSRAKKVKMGQLSLGLESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQKLDDEEEE 367
SR+ LS SG P R G+P
Sbjct: 229 ASRSLSSSATPLSSPARSG-------------PSAR------GTP--------------- 254
Query: 368 KKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPP 427
RA A P + +A L PP +TPP P L P S+SP
Sbjct: 255 ----------------RAPAHPSQPKPKGLQA-LRPPQVTPPRKDAAPALGPLSSSPLAT 297
Query: 428 LCPPPPPPVSPPP----LPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAERE 483
P PP S PP LPSPP P + P + AT S PPL+P
Sbjct: 298 PSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPS-PPLSP---LATP 353
Query: 484 AARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTP 543
+A P PP P + PP SP P + S S ++ P
Sbjct: 354 PPQAPPALALPPLQAPPSPPASPPL-SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP 412
Query: 544 RRFMDEDPPKPPKVEVS---PVLRPPITTSPPVPQEPAPVPSPPRAPT---PPSTPVPLP 597
PP P V S P PP +PP+ P+P SPP +P+ PP P PL
Sbjct: 413 -----FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA 467
Query: 598 EKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAP----ATSSRRPLLLRAPQFT 653
+ + P +L PP A P PPA P AP A+ PL PQ
Sbjct: 468 APPLQLAKPPPQAPPALA---TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP 524
Query: 654 PSEAHLKIYESVLTPPPLGAPEAPEPEPPPADD------------SPAEPEPRAVGRTNH 701
P A + + +PP +AP P P D +P P P + ++
Sbjct: 525 PVLA-APLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSST 583
Query: 702 LSLPRFA----PVVTTPVKA---EVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALP 754
LS P A +TP + + P G A S P + L A +
Sbjct: 584 LSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAE------LAACHPAAWSRGPA 637
Query: 755 PPQPQLQPPPSPQQMPP 771
PP P +P PP
Sbjct: 638 PPLAFRGAPGAPLPWPP 654
Score = 110 bits (274), Expect = 2e-23
Identities = 166/621 (26%), Positives = 214/621 (34%), Gaps = 156/621 (25%)
Query: 402 PPPPLTPPA---------------------------PSPPPPLPPPSTSPPPPLC----P 430
PPPP+TP A P P P TS PP
Sbjct: 35 PPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPPASGRGERA 94
Query: 431 PPPPPVSPPPLPSP--------PPPPAQEEQEESPPPVVP---ATCSRKR---------- 469
PP SP P+ SP P P Q+ S V AT + KR
Sbjct: 95 PPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRD 154
Query: 470 --GRPPLTPSQRAEREAARAGPEGTSP---PTPTPSTATGGPPEDSPTVAPKSTT----- 519
G P TPS R + AG E P P+ P T GP + + + STT
Sbjct: 155 TSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPA 214
Query: 520 --------------FLKNIRQFIMPVVS-ARSSRVIK-TPRRFMDEDPPKP--------- 554
+++ P+ S ARS + TPR PKP
Sbjct: 215 ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPP 274
Query: 555 ----PKVEVSPVLRP----PITT-SPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILR 605
P+ + +P L P P+ T SP P P+ PS P+PP+TP P + + L
Sbjct: 275 QVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATP---PSQATTSLG 331
Query: 606 EPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESV 665
PT + T LP PP +P P P PPA
Sbjct: 332 SPTLQATHSF--LPSPPLSPLATPPPQAPPA----------------------------- 360
Query: 666 LTPPPLGAPEAPEPEPPP---ADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPH 722
L PPL AP +P PP A SP P AV HL F+P + PV+A SP
Sbjct: 361 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAV----HLLQAPFSPPPSPPVQAPFSPP 416
Query: 723 GAPALSNG--PQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGV 780
+P +S P +QA LQ P A PP P PPP Q PPL + +
Sbjct: 417 ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP--QAPPPLAAPPLQ-L 473
Query: 781 GSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAV--KQISD 838
P L+ Q +AS+P+SP A V +
Sbjct: 474 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ 533
Query: 839 RGPVRSEDESVEAKRERPS-GPESPVQGPRIKHVCRHAAVALGQARAMVPEDVPRLSALP 897
P +++A R P+ GP++ V GPR L A A P P S
Sbjct: 534 VPPSPPASPTLQAPRRPPTPGPDTSVSGPR-----------LTLALAPGPPPPPSRSPSS 582
Query: 898 LRDRQDLATEDTSSASETESV 918
DLA +S+ S E +
Sbjct: 583 TLSGPDLAGHSSSATSTPEEL 603
Score = 98.6 bits (244), Expect = 7e-20
Identities = 103/376 (27%), Positives = 133/376 (35%), Gaps = 91/376 (24%)
Query: 392 PAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQE 451
P + +A PP P +PS PP P + PPL PP PP SPP PS PPP
Sbjct: 404 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP--- 460
Query: 452 EQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSP 511
++PPP+ PPL + A+ P+ P A PP P
Sbjct: 461 ---QAPPPL---------AAPPL--------QLAKPPPQAPPALATPPLQALPSPPASFP 500
Query: 512 TVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSP 571
AP S P + P P + PVL P+ P
Sbjct: 501 GQAPFS-------------------------PSASLPMSPLATPPPQAPPVLAAPLLQVP 535
Query: 572 PVPQEPAPVPSPPRAPTP-PSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPA 630
P P + +P R PTP P T V P LT L P PPPPP+
Sbjct: 536 PSPPASPTLQAPRRPPTPGPDTSVSGPR---------------LTLAL---APGPPPPPS 577
Query: 631 PSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAE 690
SP +T S L + T + L+ Y+S P GA +P PP A+ +
Sbjct: 578 RSP---SSTLSGPDLAGHSSSATSTPEELRGYDS---GPEGGAAASP---PPDAELAACH 628
Query: 691 PEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLP 750
P + G L+ R AP P P A L +T+ P
Sbjct: 629 PAAWSRGPAPPLAF-RGAPGAPLPWPPATGPGSADGLCTIYETEG--------------P 673
Query: 751 QALPPPQPQLQPPPSP 766
++ P L P PSP
Sbjct: 674 ESATPAPGALDPGPSP 689
Score = 84.3 bits (207), Expect = 1e-15
Identities = 78/287 (27%), Positives = 104/287 (36%), Gaps = 47/287 (16%)
Query: 386 VAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPP---PPLCPPP-----PPPVS 437
V+ P ++ + PP PP+P PP+ P +T PP PPL PP PPP +
Sbjct: 421 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA 480
Query: 438 PPPLPSPP----PPPAQEEQEESP-------------------PPVVPATCSRKRGRPPL 474
PP L +PP P P ++P PPV+ A + PP
Sbjct: 481 PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPA 540
Query: 475 TPSQRAEREAARAGPE-GTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVS 533
+P+ +A R GP+ S P T + A G PP P+ +P ST P ++
Sbjct: 541 SPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP--PSRSPSST--------LSGPDLA 590
Query: 534 ARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTP 593
SS TP D SP + P P P P P P
Sbjct: 591 GHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAP-PLAFRGAPGAP 649
Query: 594 VPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATS 640
+P P + E P A P P A P P+P TS
Sbjct: 650 LPWPPATGPGSADGL----CTIYETEGPESATPAPGALDPGPSPGTS 692
Score = 75.5 bits (184), Expect = 7e-13
Identities = 124/508 (24%), Positives = 178/508 (35%), Gaps = 94/508 (18%)
Query: 1920 APRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFED 1979
APR P+R + PP + R PP A + G ++ PG A P LG
Sbjct: 74 APRAGPTRTSRPPASGRGE-RAPP------AKNTSPGPVSSPGRASGTTRPGPLGQ---- 122
Query: 1980 MEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPV 2039
GL + + A TE + ++AGA + G + + SR
Sbjct: 123 ----KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG--- 175
Query: 2040 TVVSAPGLAPSATPGAPRIEQLDGVDDGTD--------------SEAEAVQQPRGQG--- 2082
T V P APSA P P V ++ S +Q+P +
Sbjct: 176 TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS 235
Query: 2083 --TPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAP 2140
TP S P G A P + P L+ L P PR+++ P
Sbjct: 236 SATPLSSPARSGPSARGTPRAPAHPSQPKPKG-----LQALRPPQV--TPPRKDAAPALG 288
Query: 2141 PLANG--SQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLG 2198
PL++ + PS SP+ P P ++ L PA P + TS LG
Sbjct: 289 PLSSSPLATPSPSAPPSPSAP----------PSLQTLPSPPATPPSQATTS-------LG 331
Query: 2199 QVFVKMAGEGEPVPP--PVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPP 2256
++ P PP P+ PP P AP + LPP + P PP
Sbjct: 332 SPTLQATHSFLPSPPLSPLATPP------PQAPPALALPP-----------LQAPPSPPA 374
Query: 2257 PPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGL 2316
PPL+ + + P +P A+ + + SPP PP +AP + P
Sbjct: 375 SPPLSPLATPSPQAPNALAVHLLQAPF----SPPPSPPVQAPFSPPASPPVSPSATPPSQ 430
Query: 2317 GSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLPLPEDGPPQVPDG---P 2373
+ ++ P P ++P PL +P L L + PPQ P P
Sbjct: 431 APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL--AAPPLQLAKP-PPQAPPALATP 487
Query: 2374 PDLLLESQWHHYSGEA--SSSEEEPPSP 2399
P L S + G+A S S P SP
Sbjct: 488 PLQALPSPPASFPGQAPFSPSASLPMSP 515
Score = 74.7 bits (182), Expect = 1e-12
Identities = 142/589 (24%), Positives = 189/589 (32%), Gaps = 150/589 (25%)
Query: 1913 SRRPSPLAPRPPPSRWASPPLKTSPQLRV----------------------------PPP 1944
+R P L PRPP S PP+ T LRV P
Sbjct: 19 ARAPGLLTPRPPGSPRPPPPV-TPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRA 77
Query: 1945 TSVVTALTPTS--GELAPP----GPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLL 1998
T+ P S GE APP P P P G GL + + A
Sbjct: 78 GPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGK 137
Query: 1999 GTEPFQEEIVAAGAMGSSHG-GPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPR 2057
TE + ++AGA + G PG S +R T V P APSA P P
Sbjct: 138 ATEAPKRSALSAGARRDTSGPTPG----TPSPAMARRSRAAGTEVGLPRPAPSARPRPPT 193
Query: 2058 IEQLDGVDDGTD--------------SEAEAVQQPRGQ-----GTPPSGPGVVRAGVLGA 2098
V ++ S +Q+P + TP S P G
Sbjct: 194 EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGT 253
Query: 2099 AGDRARPPEDLPSEIVDFVLKNLGGP--------GDGGAGPREESLPPAPPLANGSQPSQ 2150
A P + P + + P G + P P APP + Q
Sbjct: 254 PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQ 313
Query: 2151 GLTASPADPTRTFAWLPGAPGVRVL-------SLGPAPEPPKPATSKIILVNKLGQVFVK 2203
L + PA P G+P ++ L P PP A + L
Sbjct: 314 TLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALAL---------- 363
Query: 2204 MAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLV 2263
PP++ PP PP P +P + P P L V + P PPP PP+
Sbjct: 364 ---------PPLQAPPSPPASPPLSPLATPSPQAP--NALAVHLLQAPFSPPPSPPVQAP 412
Query: 2264 LS-------SGPASPPRQA--------IRV-------KRVSTFSGRSPPAPPPYKAPRLD 2301
S S A+PP QA ++V +S + P APPP AP L
Sbjct: 413 FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL- 471
Query: 2302 EDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLPL 2361
+ ++ PQ P + TP ++ + P PA P + L
Sbjct: 472 ---QLAKPPPQAP---------PALATPPLQAL-----PSPPASFPGQAPFSPSASLPMS 514
Query: 2362 PEDGPPQVPDGPPDLLLESQWHHYSGEASSSEEEPPSPDDKEN-QAPKR 2409
P PP P PP L A+ + PPSP QAP+R
Sbjct: 515 PLATPP--PQAPPVL------------AAPLLQVPPSPPASPTLQAPRR 549
Score = 71.6 bits (174), Expect = 1e-11
Identities = 111/418 (26%), Positives = 148/418 (35%), Gaps = 72/418 (17%)
Query: 1807 SPAPSSEPPGGEDPPLDTDVLVPGAPERH------SPIQNL------DPPLRPDSGSAPP 1854
+P+PS+ P P L T P P SP PPL P + PP
Sbjct: 297 TPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSP-LATPPP 355
Query: 1855 PAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSR 1914
AP + + ++ P P+ PL ++ PSP +P++L H+ P+PP ++
Sbjct: 356 QAPPALALPPLQAPPSPPASPPLSPLA---TPSPQAPNALAVHLLQAPFSPPPSPPVQAP 412
Query: 1915 RPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLG 1974
P +P P S A+PP + P L PP V P S ++P P PP
Sbjct: 413 FSPPASP--PVSPSATPPSQAPPSLAAPP--LQVPPSPPASPPMSPSATPPPQAPPPLAA 468
Query: 1975 PDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRY 2034
P + A A L T P Q A + +S G S S P S
Sbjct: 469 PPLQ--------LAKPPPQAPPALATPPLQ----ALPSPPASFPGQAPFSPSASLPMSPL 516
Query: 2035 IHFP---VTVVSAPGL----APSATP--GAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPP 2085
P V++AP L +P A+P APR G D + G PP
Sbjct: 517 ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPP 576
Query: 2086 S-GPGVVRAG--VLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAG------------ 2130
S P +G + G + PE+L GP G A
Sbjct: 577 SRSPSSTLSGPDLAGHSSSATSTPEELRGYD--------SGPEGGAAASPPPDAELAACH 628
Query: 2131 PREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPG-APGVRVLSLGPAPEPPKPA 2187
P S PAPPLA P L PA PG A G+ + PE PA
Sbjct: 629 PAAWSRGPAPPLAFRGAPGAPLPWPPATG-------PGSADGLCTIYETEGPESATPA 679
Score = 68.6 bits (166), Expect = 8e-11
Identities = 98/358 (27%), Positives = 130/358 (36%), Gaps = 70/358 (19%)
Query: 1810 PSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPN 1869
PS PP PPL VP +P PP+ P S + PP AP + +++
Sbjct: 428 PSQAPPSLAAPPLQ----VPPSPPA-------SPPMSP-SATPPPQAPPPLAAPPLQLAK 475
Query: 1870 YSPSRRP-LGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRW 1928
P P L LPSP P P P S SPLA PP +
Sbjct: 476 PPPQAPPALATPPLQALPSP----------PASFPGQAPFSPSASLPMSPLATPPPQA-- 523
Query: 1929 ASPPLKTSPQLRVPP-----PTSVVTALTPTSG-ELAPPGP------APSPPPPEDLGPD 1976
PP+ +P L+VPP PT PT G + + GP AP PPPP P
Sbjct: 524 --PPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPS 581
Query: 1977 FEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEES---SPTSR 2033
S LS DL +S + P + +G G + P +E + + SR
Sbjct: 582 -------STLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSR 634
Query: 2034 YIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEA-EAVQQPRGQGTPPSGPGVV- 2091
P+ APG AP P A DG+ ++E E+ G P PG
Sbjct: 635 GPAPPLAFRGAPG-APLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSG 693
Query: 2092 -RAGVLGAAGDRARPPED----------LPSEIVDFVLKNL-------GGPGDGGAGP 2131
+A AG +R P+ L + +V +L G G G GP
Sbjct: 694 GKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGP 751
Score = 68.2 bits (165), Expect = 1e-10
Identities = 149/624 (23%), Positives = 206/624 (33%), Gaps = 130/624 (20%)
Query: 1850 GSAPPPAPRSFSGARIKVPNYSPSRRPL----GGVSFGPLP--SPGSPSSLTHHIPTVGD 1903
GS PP P + + R+ + R+PL GG+ +P +P + + T P G
Sbjct: 31 GSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPPASGR 90
Query: 1904 PDFPAPPRRSRRPSPLAP--------RPPP----------------SRWASPPLKTSPQL 1939
+ APP ++ P P++ RP P + P +++
Sbjct: 91 GE-RAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSA 149
Query: 1940 RVPPPTSVVTALTPTSG----------ELAPPGPAPS--PPPPEDLGPDFEDMEVVSGLS 1987
TS T TP+ E+ P PAPS P PP + GP
Sbjct: 150 GARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE-GP------------ 196
Query: 1988 AADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGL 2047
+ A+ TEP AA S+ GG P SR + T +S+P
Sbjct: 197 RKSVSSASEHSTTEPSP----AARRRPSAGGGL-------QRPASRSLSSSATPLSSPAR 245
Query: 2048 APSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPE 2107
+ + G PR +A++ P Q TPP G L ++ P
Sbjct: 246 SGPSARGTPRAPAHPS--QPKPKGLQALRPP--QVTPPRKDAAPALGPLSSSPLATPSPS 301
Query: 2108 DLPSEIVDFVLKNLGGPGDGGAGPREESL-----------------------PPAPPLAN 2144
PS L+ L P SL PP P A
Sbjct: 302 APPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL 361
Query: 2145 GSQPSQGLTASPADPTRTFAWLPG--APGVRVLSLGPAP--EPPKPATSKIILVNKLGQV 2200
P Q + PA P + P AP + L AP PP P V
Sbjct: 362 ALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV 421
Query: 2201 FVKMAGEGEPVP----PPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPP 2256
+ P PP++ PP PP P +P++ P P P + + +P P P
Sbjct: 422 SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP 481
Query: 2257 P----PPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQ 2312
P PPL L S PAS P QA S SP A PP PQ
Sbjct: 482 PALATPPLQ-ALPSPPASFPGQAPFSPSASL--PMSPLATPP----------------PQ 522
Query: 2313 VPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLPLPEDGPPQVPDG 2372
P + + +V P + RP P + S + L P GPP P
Sbjct: 523 APPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP----GPPPPPSR 578
Query: 2373 PPDLLLES-QWHHYSGEASSSEEE 2395
P L +S A+S+ EE
Sbjct: 579 SPSSTLSGPDLAGHSSSATSTPEE 602
Score = 67.0 bits (162), Expect = 2e-10
Identities = 126/501 (25%), Positives = 171/501 (34%), Gaps = 90/501 (17%)
Query: 1785 PWGPREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPP 1844
P P A A + + PAPS+ P + P + V A E + +
Sbjct: 160 PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKS---VSSASEHSTTEPSPAAR 216
Query: 1845 LRPDSGSA-PPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGD 1903
RP +G PA RS S + P SP+R G + G +P PS
Sbjct: 217 RRPSAGGGLQRPASRSLSSSA--TPLSSPARS--GPSARGTPRAPAHPSQPKPKGLQALR 272
Query: 1904 PDFPAPPRRSRRP-------SPLAPRPPPSR----WASPPLKTSPQLRVPPPTSVVTA-- 1950
P PPR+ P SPLA P PS A P L+T P PP+ T+
Sbjct: 273 PPQVTPPRKDAAPALGPLSSSPLAT-PSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLG 331
Query: 1951 ---LTPTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEI 2007
L T L P +P PP P + + S + L P
Sbjct: 332 SPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNA 391
Query: 2008 VAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDG 2067
+A + + S P S + P + ++P ++PSATP + L
Sbjct: 392 LAVHLLQAPF----------SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL------ 435
Query: 2068 TDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDG 2127
A +Q P +PP+ P + A PP P + L+ L P
Sbjct: 436 ---AAPPLQVP---PSPPASPPM---------SPSATPPPQAPPPLAAPPLQ-LAKP--- 476
Query: 2128 GAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPA 2187
PP P A + P Q L + PA + P A L + P PP A
Sbjct: 477 ---------PPQAPPALATPPLQALPSPPASFPGQAPFSPSAS----LPMSPLATPPPQA 523
Query: 2188 TSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVG 2247
+L L QV P P ++ P PPT P S GP L +
Sbjct: 524 PP--VLAAPLLQV-----PPSPPASPTLQAPRRPPTPGPDTSVS-----GPRLTL----- 566
Query: 2248 VVRPAPPPPPPPLTLVLSSGP 2268
+ P PPPPP SGP
Sbjct: 567 ALAPGPPPPPSRSPSSTLSGP 587
Score = 34.7 bits (78), Expect = 1.3
Identities = 31/109 (28%), Positives = 39/109 (35%), Gaps = 14/109 (12%)
Query: 1033 DESPEASPGPPGPRRGAGAGGPREEVVAHPGPEEQDSL---LQRKSARRCVKQRPSYDIF 1089
+ +P A PGP G R PGP Q L + AR + P
Sbjct: 92 ERAPPAKNTSPGPVSSPG----RASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSAL 147
Query: 1090 EDSDDSEPGGP----PAP---RRRTPRENELPLPEPEEQSRPRKPTLQP 1131
+ GP P+P RR E+ LP P +RPR PT P
Sbjct: 148 SAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGP 196
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 115 bits (288), Expect = 6e-25
Identities = 151/598 (25%), Positives = 228/598 (38%), Gaps = 88/598 (14%)
Query: 355 KKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPP 414
KK K+ +E + E K+ +E+ V EE K LPP + P P
Sbjct: 10453 KKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPV 10512
Query: 415 PPLPPPSTSPPP--------------PLCPPPPPPVSPPPLPSPPP--------PPAQEE 452
PP P PP P+ PP P V P +P P P A
Sbjct: 10513 PPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPP 10572
Query: 453 QEESPPPVVPATCSR--KRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDS 510
+ ESPPP VP + P P ++ E + PE +P P PP
Sbjct: 10573 KPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKV-PE--APKEVVPEKKVPVPPPKK 10629
Query: 511 PTV-------APKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVL 563
P V PK K + + I P + V + P E+PP E P
Sbjct: 10630 PEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAA 10689
Query: 564 RPPITTSP--PVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELP-P 620
P +T P PVP++ AP A P PV +PE + ++ E +++P
Sbjct: 10690 PPQVTVPPKKPVPEKKAPAVV---AKKPELPPVKVPEVPKEVVPE---------KKVPLV 10737
Query: 621 PPPAPPPPPAPSPP-PAPATSSRRPLLLRAPQFTPSEAHLKIYESVL-TPPPLGAPEAPE 678
P P PPA P P ++ + + P+ P++ + VL P + PE E
Sbjct: 10738 VPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAE 10797
Query: 679 PEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPH-GAPALSNGPQTQAQL 737
PP + P E P ++ PV PV E P PA+ P+
Sbjct: 10798 SPPPEVYEEPEEIAPE-----EEIAPEEEKPV---PVAEEEEPEVPPPAVPEEPKK---- 10845
Query: 738 LQPLQALQTQLLPQALPPPQPQ---------LQP-PPSPQQMPPLE--KARIAGVGSLPL 785
+ P + + P+A PP +P+ L+P PP P PP E K +I + ++P
Sbjct: 10846 IIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPK 10905
Query: 786 SGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISDRGPVRSE 845
V EK + ++ ++ K+ ++KV +P EEV +K + + P E
Sbjct: 10906 KKVPEKP-QVPEKVELTPLKV-PGGEKKVRKLLPERKPEPKEEV--VLKSVLRKRP-EEE 10960
Query: 846 DESVEAKR----ERPSGPESPVQGPRIKHVCRHAAVALGQARAMVPEDVPRLS-ALPL 898
+ VE K+ ++P+ PE P P+ V + + P VP + A+PL
Sbjct: 10961 EPKVEPKKLEKVKKPAVPEPP--PPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPL 11016
Score = 101 bits (251), Expect = 1e-20
Identities = 176/853 (20%), Positives = 289/853 (33%), Gaps = 163/853 (19%)
Query: 110 EEESSDGESDEEEFQGFHSDED-VAPSSLRSALRSQRGRAPRGRGRKHKTTPLPPPRLAD 168
EE + E++ E++ E+ V L + R+ K L P A
Sbjct: 9512 EEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAK 9571
Query: 169 VAPTPPKTPARKRGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPRRSRGRPPG--- 225
+ PP + E+ V A + P+ P EP P + PP
Sbjct: 9572 IEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPE----EPKKPVPEKKVPPKVIK 9627
Query: 226 ----RPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRR 281
PA R Q + V + K E PP K + P P
Sbjct: 9628 MEEPLPAKVTERHMQITQEEKVLVAVTKKEAPP------------KARVPEEPKRAVPEE 9675
Query: 282 GGQSSRGGRGGRGRGRGGGLPFVIKFVSRAKKVKMGQLSLGLESGQGQGQHEESWQDVPQ 341
+ R + V +F R + VK ++S+ + Q E + + +
Sbjct: 9676 KVLKLKPKREEEPPAK------VTEF--RKRVVKEEKVSIEAPKREPQPIKEVTIMEEKE 9727
Query: 342 RRVGSGQGGSPCWKKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKL 401
R + +++E + +E + K+ EE + E ++ E E E EE
Sbjct: 9728 RAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYIT 9787
Query: 402 PPPPLTPPAPSPPPPLPPPSTSPPPPL----CPPPPPPVSPPPLPSPPPPPAQEEQEESP 457
P P P P P+P +PP + P PV P PPPP EE ++
Sbjct: 9788 EPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVF 9847
Query: 458 PPVVPATCSRKR--------GRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPED 509
+ + +++ + P+ P + E + +PP P PE+
Sbjct: 9848 EEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEE 9907
Query: 510 -----------SPTVAPKSTTFLKNIRQFIM--PVVSARSSRVIKTPRRFMDED------ 550
+ + ++ +FI VV +V + PR+ + E+
Sbjct: 9908 VAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPV 9967
Query: 551 --------------PPKP--------PKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPT 588
P KP PK E P + P PVP+E PVP P +
Sbjct: 9968 PKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEA 10027
Query: 589 PPS--------------TPVPLPEKRRSILREPTFRWTSLTRELPP----PPPAP----- 625
PP+ PVP P+K + P + + ++L P P P P
Sbjct: 10028 PPAKVPEVPKKPVPEKKVPVPAPKK----VEAPPAKVPEVPKKLIPEEKKPTPVPKKVEA 10083
Query: 626 PPPPAP---SPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPE----APE 678
PPP P P P P + +L + P E L E VL PE PE
Sbjct: 10084 PPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPE 10143
Query: 679 PEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLL 738
E P ++ PE V F P + EV P P +
Sbjct: 10144 EEEIPPEEEEVPPEEEYVPEEE-----EFVP------EEEVLPEVKPKV----------- 10181
Query: 739 QPLQALQTQLLPQALPPPQPQLQPPPSPQQ--MPPLEKARIAGVGSLPLSGVEEKMFSLL 796
+P P P+++ + ++ +P E+A A V +P VEEK L
Sbjct: 10182 -------------PVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVP-KKVEEKRIILP 10227
Query: 797 KRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISDRGPVRSEDESVEAKRERP 856
K +V ++ ++ +++ P+S ++ E +++++ + P R + +A E P
Sbjct: 10228 KEEEVLPVEVTEEPEEE-----PISE-EEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAP 10281
Query: 857 SGPESPVQGPRIK 869
+ V+ P K
Sbjct: 10282 TPVPKKVEAPPAK 10294
Score = 93.6 bits (231), Expect = 2e-18
Identities = 153/660 (23%), Positives = 218/660 (33%), Gaps = 140/660 (21%)
Query: 161 LPPPRLADVAP----TPPK---TPARKRGEEGTERMVQALTELLRRAQAPQAPRSRACEP 213
+PP ++ +V P P K P K+ E ++ +A E++ + P P + P
Sbjct: 10490 VPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKK---P 10546
Query: 214 STPRRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVP--VKHQTGSWKCKEG 271
P P + A P ++ +A+ PKPE PPP VP K K
Sbjct: 10547 EVPPTKVPEVP-KAAVPEKKVPEAIP--------PKPESPPPEVPEAPKEVVPEKKVPAA 10597
Query: 272 PGPGPG-TPRRGGQSSRGGRGGRGRGRGGGLPFVIKFVSRAKKVKMGQLSLGLESGQGQG 330
P P TP + +P K V KKV +
Sbjct: 10598 PPKKPEVTPVK-------------------VPEAPKEVVPEKKVPV-------------- 10624
Query: 331 QHEESWQDVPQRRVGSGQGGSPCWKKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEM 390
+VP +V P E+K+ E K E + EE EE VA E
Sbjct: 10625 -PPPKKPEVPPTKVPE----VPKVAVPEKKV-PEAIPPKPESPPPEVFEEPEE--VALEE 10676
Query: 391 MPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPP-PPVSPPPLPSPPPPPA 449
PA EE P P PP + PP P P P + P PPV P +P P
Sbjct: 10677 PPAEVVEE----PEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVP-- 10730
Query: 450 QEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPED 509
E+ P VVP + P P + + + PP P E+
Sbjct: 10731 ----EKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEE 10786
Query: 510 SPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITT 569
P V + + P V + +E+ P P E P + PP
Sbjct: 10787 KPAVP------VPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVP 10840
Query: 570 SPP---VPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAP- 625
P +P++ PV P AP P P PEK ++ +P L PPPPPAP
Sbjct: 10841 EEPKKIIPEKKVPVIKKPEAPPPKE---PEPEK---VIEKP-----KLKPRPPPPPPAPP 10889
Query: 626 --------------PPPPAPSPPPAPATSSRRPLLLRA---------PQFTPSEAHLKIY 662
P P P P PL + P+ P +
Sbjct: 10890 KEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVL 10949
Query: 663 ESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFA--------PVVTTP 714
+SVL P EP+ PA PEP + +P P
Sbjct: 10950 KSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPE 11009
Query: 715 VKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEK 774
+K + P AP P+ + + ++P PP +P+ P +P +P + K
Sbjct: 11010 IKPAI-PLPAPEPKPKPEAEVKTIKP-------------PPVEPEPTPIAAPVTVPVVGK 11055
Score = 85.1 bits (209), Expect = 8e-16
Identities = 152/654 (23%), Positives = 213/654 (32%), Gaps = 156/654 (23%)
Query: 157 KTTPLPPPRLADVAPTP-PKTPARKRGEEGTERMVQALTELLRRAQAPQAPRSRACEPST 215
K P+PPP+ +V PT P+ P E+ + E + P+AP+ E
Sbjct: 10536 KKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPE-SPPPEVPEAPKEVVPEKKV 10594
Query: 216 PRRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIP---KPEPPPPVVP--VKHQTGSWKCKE 270
P +P P ++ VV E V +P KPE PP VP K K E
Sbjct: 10595 PAAPPKKPEVTPVKVPEAPKE--VVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPE 10652
Query: 271 GPGPGPGTPRRGGQSSRGGRGGRGRGRGGGLPFVIKFVSRAKKVKMGQLSLGLESGQGQG 330
P P +P +V + LE +
Sbjct: 10653 AIPPKPESP-------------------------------PPEVFEEPEEVALEEPPAEV 10681
Query: 331 QHEESWQDVPQRRVGSGQGGSPCWKKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEM 390
E PQ V P K +K KK E K E +E V E+
Sbjct: 10682 VEEPEPAAPPQVTV-------PPKKPVPEKKAPAVVAKKPELPPVKVPEVPKE-VVPEKK 10733
Query: 391 MPAAEKEEAKLPP--------------------PPLTPPA------------PSPPPPLP 418
+P ++ + PP P PPA P P+P
Sbjct: 10734 VPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVP 10793
Query: 419 PPSTSPPPPLCPPP---PPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLT 475
+ SPPP + P P P P P A+EE+ E PPP VP + +
Sbjct: 10794 ERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKK------II 10847
Query: 476 PSQRAEREAARAGPEGTSPPTPTPSTATGGP-----PEDSPTVAPKSTTFLKNIRQFIMP 530
P ++ PE P P P P P P PK
Sbjct: 10848 PEKKV---PVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKED------------ 10892
Query: 531 VVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPP 590
V + ++ P++ + E P P KVE++P+ P ++ P R P P
Sbjct: 10893 -VKEKIFQLKAIPKKKVPEKPQVPEKVELTPL-------KVPGGEKKVRKLLPERKPEPK 10944
Query: 591 STPVPLPEKRRSILR------EPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRR- 643
V +S+LR EP L + P P PPPP P + R
Sbjct: 10945 EEVV-----LKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRER 10999
Query: 644 --PLLLRAPQFTPSEAHLKIYESVLTPPPLGAPE---APEPEPPPADDSPAEPEPRAVGR 698
P + P+ P+ PL APE PE E P EPEP +
Sbjct: 11000 KIPEPTKVPEIKPA-------------IPLPAPEPKPKPEAEVKTIKPPPVEPEPTPI-- 11044
Query: 699 TNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGP--QTQAQLLQPLQALQTQLLP 750
+ P PVV +A+ +P A GP + P++A + +L P
Sbjct: 11045 ----AAPVTVPVVGKKAEAK-APKEEAAKPKGPIKGVPKKTPSPIEAERRKLRP 11093
Score = 79.3 bits (194), Expect = 5e-14
Identities = 91/368 (24%), Positives = 139/368 (37%), Gaps = 49/368 (13%)
Query: 157 KTTPLPPPRLADVAPTP-----PKTPARKRGEEGTERMVQALTELLRRAQ-APQ----AP 206
K +PP ++ +V P P P +R E + + E+ + AP+ P
Sbjct: 10766 KKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVP 10825
Query: 207 RSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVPVKHQT-GS 265
+ EP P PP P P + ++ + I KPE PPP P +
Sbjct: 10826 VAEEEEPEVP------PPAVPEEP-----KKIIPEKKVPVIKKPEAPPPKEPEPEKVIEK 10874
Query: 266 WKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGGLPFVIKFVSRAKKVKMGQL--SLGL 323
K K P P P P + + F +K + + K + Q+ + L
Sbjct: 10875 PKLKPRPPPPPPAPPKEDVKEK--------------IFQLKAIPKKKVPEKPQVPEKVEL 10920
Query: 324 ESGQGQGQHEESWQDVPQRRVGSGQG---GSPCWKKQEQKLDDEEEEKKEEEEKDKEGEE 380
+ G ++ + +P+R+ + S K+ E++ E +K E+ +K E
Sbjct: 10921 TPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEP 10980
Query: 381 KEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPL----CPPPPPPV 436
+ V E +P K E K+P P P P PLP P P P PPP
Sbjct: 10981 PPPKPVEEVEVPTVTKRERKIPEPTKVPEI-KPAIPLPAPEPKPKPEAEVKTIKPPPVEP 11039
Query: 437 SPPPLPSPPPPPAQEEQEESPPPVVPATCSRK--RGRPPLTPSQ-RAEREAARAGPEGTS 493
P P+ +P P ++ E+ P A + +G P TPS AER R G G
Sbjct: 11040 EPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRPGSGGEK 11099
Query: 494 PPTPTPST 501
PP P T
Sbjct: 11100 PPDEAPFT 11107
Score = 79.0 bits (193), Expect = 6e-14
Identities = 110/515 (21%), Positives = 184/515 (35%), Gaps = 48/515 (9%)
Query: 364 EEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTS 423
EE +EEEE E EE ++P E + P P P P P PP+
Sbjct: 9919 EEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKV 9978
Query: 424 PPPPLCPPPPPPVSPPPLPSPPPP-----PAQEEQEESPPPVVPATCSRKRGRPPLTPSQ 478
P P P PV P PPP P + EE P VP + P P +
Sbjct: 9979 PEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKK 10038
Query: 479 RA-EREAARAGPEGT-SPPTPTPSTATGGPPED-SPTVAPKSTTF----LKNIRQFIMPV 531
E++ P+ +PP P PE+ PT PK + R+ +
Sbjct: 10039 PVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVP 10098
Query: 532 VSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPS 591
V+ + + E+ P + EV P + V E +P P PP
Sbjct: 10099 VALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIP-PEEEEVPPE 10157
Query: 592 TPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQ 651
+PE+ + E E+ P P PAP P + ++ ++ + +
Sbjct: 10158 EEY-VPEEEEFVPEE----------EVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEE 10206
Query: 652 FTPS---EAHLKIYESVLTPP------PLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHL 702
P+ E K+ E + P P+ E PE EP ++ P EP ++ +
Sbjct: 10207 APPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPP--SIEEVEEV 10264
Query: 703 SLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQP 762
+ PR V+ V +P P P + P + + + + PP + P
Sbjct: 10265 APPRVPEVIKKAVPEAPTP--VPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVP 10322
Query: 763 PPSPQQ--MPPLEKARIAGVGSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPL 820
P++ + P ++A G L EEK+ ++ V +++ + + +P
Sbjct: 10323 KKVPEKKVLVPKKEAVPPAKGRTVL---EEKVSVAFRQEVVVKERLELEVVEAEVEEIP- 10378
Query: 821 SPGGQMEEVAGAVKQISDRGPVRSEDESVEAKRER 855
EE V++ + G +E ++ ++ R
Sbjct: 10379 -----EEEEFHEVEEYFEEGEFHEVEEFIKLEQHR 10408
Score = 73.2 bits (178), Expect = 3e-12
Identities = 103/413 (24%), Positives = 146/413 (35%), Gaps = 70/413 (16%)
Query: 338 DVPQRRVGSGQGGSPCWKKQEQKLDDEEEEKKEEEEK------------DKEGEEKEERA 385
+VP++ V + P KK+E E K+ EEK + E ++
Sbjct: 9952 EVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKP 10011
Query: 386 VAEEMMPAAEKEEAKLPPP--PLTP--PAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPL 441
V EE +P ++ + PP P P P P P+P P PP P P P
Sbjct: 10012 VPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEE 10071
Query: 442 PSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPST 501
P P P ++ E+PPP VP K+ P P + E E P
Sbjct: 10072 KKPTPVP---KKVEAPPPKVP-----KKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEE 10123
Query: 502 ATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSP 561
P E+ V P+ L + I P + ++ E+ P+ EV P
Sbjct: 10124 EEVLPEEEE--VLPEEEEVLPE-EEEIPP-----EEEEVPPEEEYVPEEEEFVPEEEVLP 10175
Query: 562 VLRPPITTSPPVP-------QEPAPVPSPPRAPTP--PSTPVPLPEKRRSILREPTFRWT 612
++P + PVP ++ +P AP P P + EKR + +E
Sbjct: 10176 EVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPV 10235
Query: 613 SLT----------RELPPPPP--------APPPPPAPSPPPAPATSSRRPLLLRAPQFTP 654
+T E+P PP APP P P + P + AP P
Sbjct: 10236 EVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAP---P 10292
Query: 655 SEAHLKI-YESVLTP------PPLGAPEAPEPEPPPADDSP-AEPEPRAVGRT 699
++ KI E V P PP PE P+ P P E P A GRT
Sbjct: 10293 AKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAKGRT 10345
Score = 71.2 bits (173), Expect = 1e-11
Identities = 151/692 (21%), Positives = 245/692 (35%), Gaps = 148/692 (21%)
Query: 329 QGQHEESWQDVPQRRVGSGQGGSPCWKKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAE 388
Q +EE +D + +V + + W++ + E +E E EE EGEE+ E A E
Sbjct: 9091 QPYYEEPDEDYEEIKVEAKKEVHEEWEEDFE----EGQEYYEREEGYDEGEEEWEEAYQE 9146
Query: 389 EMMPAAEKE------EAKLPPPPLTPPAPSPPPPLPPP------STS---PPPPLCPPPP 433
+ +KE E K+P AP PP + P TS +
Sbjct: 9147 REVIQVQKEVYEESHERKVPAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKV 9206
Query: 434 PPVSPPPLPSPPP-PPAQEEQEESPPPVVPATCSRKR--GRPPLTPSQRAEREAARAGPE 490
P VS +P P P QEE E VPA ++K + + E E + PE
Sbjct: 9207 PEVSKKIVPQKPSRTPVQEEVIEVK---VPAVHTKKMVISEEKMFFASHTEEEVSVTVPE 9263
Query: 491 -----------------GTSPPTPTPSTATGGPPED-SPTVAPKSTTFLKNIRQFIMPVV 532
PP P PE+ +P PK V
Sbjct: 9264 VQKEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKK--------------V 9309
Query: 533 SARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSP--PVPQEPAPVPSPPRAPTPP 590
+ +V + P++ + E+ P + P P + P PVP+E PVP + PP
Sbjct: 9310 EPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPP 9369
Query: 591 STPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAP 650
+ +PE ++ ++ E + T +T+ PPPA P P P R+P+ +
Sbjct: 9370 A---KVPEVQKGVVTEE--KITIVTQREESPPPAVPEIPKKKVP-----EERKPVPRKEE 9419
Query: 651 QFTPSEAHLKIYESVLTPPPLGA-PEAPEPEPPPADDSPA---EPEPRA-VGRTNHLSLP 705
+ P PP + A P+ P PE A P P PRA V + +
Sbjct: 9420 EVPP-------------PPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEK 9466
Query: 706 RFAP----VVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQ 761
RF P + EV+ H A ++ + + + + + + +
Sbjct: 9467 RFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYE 9526
Query: 762 PPPSPQQMPPLEKARIAGVGSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLS 821
P++ VEEK+ + KR + + ++ ++Q++K+ P
Sbjct: 9527 VMEEPEEYV-----------------VEEKLHIISKRVEAEPAEVTERQEKKIVLK-PKI 9568
Query: 822 PGGQMEEVAGAVKQISDRGPVRSEDESVEAKRER------PSGPESPVQGPRI------- 868
P E V + + + + K+E+ P P+ PV ++
Sbjct: 9569 PAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKM 9628
Query: 869 ------KHVCRH----------AAVALGQA--RAMVPED----VPRLSALPLRDRQDLAT 906
K RH AV +A +A VPE+ VP L L+ ++
Sbjct: 9629 EEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKR---- 9684
Query: 907 EDTSSASETESVPSRSRRGKVEAAGPGGESEP 938
E+ A TE + KV P E +P
Sbjct: 9685 EEEPPAKVTEFRKRVVKEEKVSIEAPKREPQP 9716
Score = 58.9 bits (141), Expect = 7e-08
Identities = 148/671 (22%), Positives = 225/671 (33%), Gaps = 163/671 (24%)
Query: 1788 PREE--PAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPL 1845
P EE P E E + V P E P + VP ++ + + + P
Sbjct: 10149 PEEEEVPPEEEYVPEEEEFV----PEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKK 10204
Query: 1846 RPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPD 1905
+ P P+ RI +P P+ V+ P P S + P++ + +
Sbjct: 10205 EEAPPAKVPEVPKKVEEKRIILPK-EEEVLPVE-VTEEPEEEPISEEEIPEEPPSIEEVE 10262
Query: 1906 FPAPPRRS---RRPSPLAPRPPPSRWASPPLKTS---PQLRVPPPTSVVTALTPTSGELA 1959
APPR ++ P AP P P + +PP K S P+ +VP P + A
Sbjct: 10263 EVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEKVP---------VPVQKKEA 10313
Query: 1960 PPGPAPSPPP--PED--LGPDFEDMEVVSGLSAAD----LDFAASLLGTEPFQEEIVAAG 2011
PP P P PE L P E + G + + + F ++ E + E+V A
Sbjct: 10314 PPAKVPEVPKKVPEKKVLVPKKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAE 10373
Query: 2012 AMGSSHGGPGDSSEEESSPTSRYIHFPV--TVVSAPGLAPSATPGAPRIEQLDGVDDGTD 2069
EEE Y V L R+E++ V + +
Sbjct: 10374 VEEIPE-------EEEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFE 10426
Query: 2070 SE-AEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGG 2128
+E E ++P+ PP GP + ++ PP+ P+++V
Sbjct: 10427 AEEVEVFEKPKA---PPKGPEI---------SEKIIPPKKPPTKVV-------------- 10460
Query: 2129 AGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPAT 2188
PR+E PPA P P + VRV PE P+
Sbjct: 10461 --PRKE--PPAKV--------------PEVPKKIVV----EEKVRV------PEEPRVPP 10492
Query: 2189 SKIILVNKLGQVFVKMAGEGEPVPP----PVKQPPLPPTISPTAPTSWTLPPGPLLGVLP 2244
+K+ E +PP P K+ P+PP P AP P + P
Sbjct: 10493 TKV----------------PEVLPPKEVVPEKKVPVPPAKKPEAPP-------PKVPEAP 10529
Query: 2245 VVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDG 2304
V P PPP V + P+ A+ K+V P +PPP + P ++
Sbjct: 10530 KEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPP-EVPEAPKEV 10588
Query: 2305 EASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEES---PGPLQERSP---- 2357
+ P P K P V V + P E E+ P P + P
Sbjct: 10589 VPEKKVPAAP-----------PKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKV 10637
Query: 2358 ----------------LLPLPEDGPPQVPDGPPDLLLESQWHHYSGEASSSEEEPPSPDD 2401
+ P PE PP+V + P ++ LE A EE P+
Sbjct: 10638 PEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEP------PAEVVEEPEPAAPP 10691
Query: 2402 KENQAPKRTGP 2412
+ PK+ P
Sbjct: 10692 QVTVPPKKPVP 10702
Score = 57.0 bits (136), Expect = 2e-07
Identities = 211/1057 (19%), Positives = 344/1057 (32%), Gaps = 240/1057 (22%)
Query: 130 EDVAPSSLRSALRSQRGRAPRGRGRK--HKTTPLPPPRLADVAPTP-PKTPARKRGEEGT 186
E+VAP + + + P + + P+P P+ AP P+ P + EE
Sbjct: 9298 EEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKI 9357
Query: 187 ERMVQALTELLRRAQAPQAPRSRACEPS---TPRRSRGRPPGRPAGPCRRKQQAVVVAEA 243
V E A+ P+ + E +R PP P P ++ V E
Sbjct: 9358 PVPVAKKKEA-PPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKK------VPEE 9410
Query: 244 AVTIPKPE---PPPPVVPVKHQTGSWKCKEG---PGPGPGTPRRGGQSSRGGRGGRGRGR 297
+P+ E PPPP VP + + K P P R S +
Sbjct: 9411 RKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKK---------- 9460
Query: 298 GGGLPFVIKFVSRAKKVKMGQLSLGLESGQGQGQHE----ESWQDVPQRRVGSGQGGSPC 353
V + V +LS + +HE E W + +G S
Sbjct: 9461 --------TVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEE-----EGVSIS 9507
Query: 354 WKKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSP 413
++E++ ++EE E E E EE EE V E++ +++ EA+ P +T
Sbjct: 9508 VYREEEREEEEEAEVTEYEVM----EEPEEYVVEEKLHIISKRVEAE--PAEVTERQEKK 9561
Query: 414 ---PPPLPPPSTSPPPPLCPPPPPPVSPPP-LPSPPPPPAQEEQEESPPPVVPATCSRKR 469
P +P PPP P P + P +P+P P ++E+ PPP VP
Sbjct: 9562 IVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVP-----KKEKVPPPKVP------- 9609
Query: 470 GRPPLTPSQRAEREAARAGPEGTSPPT------PTPSTATGGPPEDSPTVAPKSTTFLKN 523
E + PE PP P P+ T E + + +
Sbjct: 9610 ------------EEPKKPVPEKKVPPKVIKMEEPLPAKVT----ERHMQITQEEKVLVAV 9653
Query: 524 IRQFIMPVVSARSSRVIKTPRRFMDEDP--PKPPKVEVSPVLRPPITTSPPVPQEPAPVP 581
++ P +RV + P+R + E+ PK E P + V +E +
Sbjct: 9654 TKKEAPP-----KARVPEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIE 9708
Query: 582 SPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSS 641
+P R P P + EK R+ E A S
Sbjct: 9709 APKREPQPIKEVTIMEEKERAYTLE-----------------------------EEAVSV 9739
Query: 642 RRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNH 701
+R E + YE E E EP D E E R R
Sbjct: 9740 QR------------EEEYEEYEE------YDYKEFEEYEPTEEYDQYEEYEEREYERYEE 9781
Query: 702 LSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQ 761
P PVK V P P P + L+ + + +P P P+
Sbjct: 9782 HEEYITEPEKPIPVK-PVPEEPVPTKPKAP--------PAKVLKKAVPEEKVPVPIPKKL 9832
Query: 762 PPPSPQQMPPLEKARIAGVGSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLS 821
PP P+ V P EEK+ ++ + K +++Q + AA +P+
Sbjct: 9833 KPPPPK------------VPEEPKKVFEEKI-------RISITKREKEQVTEPAAKVPMK 9873
Query: 822 PGGQMEEVAGAVKQISDRGPVRSEDESVEAKRERPSGPESPVQGPRIKHVCRHAA----- 876
P + E V + PVR + E + E + E V HV +
Sbjct: 9874 PKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEVV-----THVEEYLVEEEEE 9928
Query: 877 --------VALGQARAMVPEDVPRLSALPLRDRQDLATEDTSSASETESVPS--RSRRGK 926
+ + ++P VP + P+ + + + VP + K
Sbjct: 9929 YIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEK 9988
Query: 927 VEAAGPGGESEPTGSGGTLAHTPRRSLPSHHGKKMRMARCGHCRGCLRVQDCGSCVNCLD 986
V P E P + P++ +P +K+ + ++
Sbjct: 9989 VPVLIPKKEKPPPAK---VPEVPKKPVPE---EKVPV----------------PVPKKVE 10026
Query: 987 KPKFGGPNTKKQCCVYRKCDKIEARKMERLAKKGRTIVKTLLPWDSDESP----EASPGP 1042
P P K+ +K +K+E K + K L+P + +P +P P
Sbjct: 10027 APPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPP 10086
Query: 1043 PGPRRGAGAGGPREEV-VAHPGPEEQDSLLQRKSARRCVKQRPSYDIFEDSDDSEPGGP- 1100
P++ RE V V P+E++ L + + P ++ + ++ P
Sbjct: 10087 KVPKK-------REPVPVPVALPQEEEVLFEEEIV-------PEEEVLPEEEEVLPEEEE 10132
Query: 1101 --PAPRRRTPRENELPLPE----PEEQSRPRKPTLQP 1131
P P E E+P E PEE+ P + P
Sbjct: 10133 VLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVP 10169
Score = 54.7 bits (130), Expect = 1e-06
Identities = 156/690 (22%), Positives = 220/690 (31%), Gaps = 137/690 (19%)
Query: 1788 PREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPG---APERHSPIQ----- 1839
PR+EP + +V E P PP ++P PE+ P+
Sbjct: 10461 PRKEPPAKVPEVPKKIVVEEKVRVPEEP--RVPPTKVPEVLPPKEVVPEKKVPVPPAKKP 10518
Query: 1840 NLDPPLRPDSGS-------APPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPS 1892
PP P++ P P P+ KVP + P V P P SP
Sbjct: 10519 EAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPP 10578
Query: 1893 SLTHHIP--TVGDPDFPAPPRRSRRPSPL--------------APRPPPSRWASPPLKTS 1936
P V + PA P + +P+ P PPP + PP K
Sbjct: 10579 PEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVP 10638
Query: 1937 PQLRVPPPTSVVTALTPTSGELAPPGPAPSPPP-----PEDLGPDFEDMEVVSGLSAADL 1991
+V P V E PP P SPPP PE++ + EVV A
Sbjct: 10639 EVPKVAVPEKKVP-------EAIPPKPE-SPPPEVFEEPEEVALEEPPAEVVEEPEPAAP 10690
Query: 1992 DFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSE--EESSPTSRYIHFPVTVVSAPGLAP 2049
++ +P E+ A P E +E P + P+ V P P
Sbjct: 10691 P-QVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKV---PLVVPKKPEAPP 10746
Query: 2050 SATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSG-PGVVRAGVLGA-----AGDRA 2103
+ P P+ + V + + V P+ PP+ P V + VL +RA
Sbjct: 10747 AKVPEVPK----EVVPE------KKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERA 10796
Query: 2104 R-PPEDLPSEIVDFVLKNLGGPGDGGAGP-REESLPPAPPLANGSQPSQGLTASPADPTR 2161
PP ++ E + + P + P EE P PP A +P + + +
Sbjct: 10797 ESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIK 10856
Query: 2162 TFAWLPGAPG---------VRVLSLGPAPEPPKPATSKIILVNKLGQVFV---KMAGEGE 2209
P AP + L P P PP PA K + K+ Q+ K E
Sbjct: 10857 K----PEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKP 10912
Query: 2210 PVPPPVKQPPLP-----PTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPP---PPPLT 2261
VP V+ PL + P P + VL V RP P P L
Sbjct: 10913 QVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEV--VLKSVLRKRPEEEEPKVEPKKLE 10970
Query: 2262 LVLSSG-PASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGG 2320
V P PP + + V T + R P P K P E P +P
Sbjct: 10971 KVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVP---------EIKPAIP------ 11015
Query: 2321 FSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLPLPEDGPPQVPDGPPDLLLES 2380
PA E P P E + P P + P P + +
Sbjct: 11016 ---------------------LPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVG 11054
Query: 2381 QWHHYSGEASSSEEEPPSPDDKENQAPKRT 2410
+ EA + +EE P PK+T
Sbjct: 11055 K----KAEAKAPKEEAAKPKGPIKGVPKKT 11080
Score = 52.0 bits (123), Expect = 8e-06
Identities = 119/574 (20%), Positives = 178/574 (31%), Gaps = 97/574 (16%)
Query: 1788 PREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVL----VPGAPERHSPIQNLDP 1843
P + P +AA + + + P E P E P +V+ VP AP + + +
Sbjct: 10550 PTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKV 10609
Query: 1844 PLRPDS----GSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIP 1899
P P P P P+ KVP P V P P SP P
Sbjct: 10610 PEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEP 10669
Query: 1900 -----------TVGDPDFPAPPR----------RSRRPSPLAPRP--PPSRWASPPLKTS 1936
V +P+ APP+ + P+ +A +P PP + P +
Sbjct: 10670 EEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVV 10729
Query: 1937 PQLRVP---------PPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLS 1987
P+ +VP PP V E P PP + P+ V+
Sbjct: 10730 PEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKV-PEVPKKPVLEEKP 10788
Query: 1988 AADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGL 2047
A + A E ++E P + + EE PV P +
Sbjct: 10789 AVPVPERAESPPPEVYEE--------------PEEIAPEEEIAPEEEKPVPVAEEEEPEV 10834
Query: 2048 APSATPGAPR----------IEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLG 2097
P A P P+ I++ + + +++P+ + PP P
Sbjct: 10835 PPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPP--------- 10885
Query: 2098 AAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPA 2157
A P ED+ +I F LK + P + +P L P
Sbjct: 10886 ----PAPPKEDVKEKI--FQLKAI----PKKKVPEKPQVPEKVELTPLKVPGGEKKVRKL 10935
Query: 2158 DPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNK-----------LGQVFVKMAG 2206
P R VL P E PK K+ V K + +V V
Sbjct: 10936 LPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVT 10995
Query: 2207 EGE-PVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLS 2265
+ E +P P K P + P I AP P + + P P P P + +V
Sbjct: 10996 KRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGK 11055
Query: 2266 SGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPR 2299
A P++ K G P P +A R
Sbjct: 11056 KAEAKAPKEE-AAKPKGPIKGVPKKTPSPIEAER 11088
Score = 48.1 bits (113), Expect = 1e-04
Identities = 54/234 (23%), Positives = 87/234 (37%), Gaps = 34/234 (14%)
Query: 2190 KIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGV- 2248
++I V + +V V + P P + + +PP PT PP + V + V
Sbjct: 10420 RVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVE 10479
Query: 2249 ----VRPAPPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDG 2304
V P PP + VL PP++ + K+V + P APPP K P ++
Sbjct: 10480 EKVRVPEEPRVPPTKVPEVL------PPKEVVPEKKVPVPPAKKPEAPPP-KVPEAPKEV 10532
Query: 2305 EASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLPLPED 2364
+ P P P V P P + E P P PE
Sbjct: 10533 VPEKKVPVPP--------------PKKPEVPPTKVPEVPKAAVPEKKVPEAIP--PKPES 10576
Query: 2365 GPPQVPDGPPDLLLESQWHHYSGEASSSEEEPPSPDDKENQAPKRTGPHLRFEI 2418
PP+VP+ P +++ E + ++ ++P K +APK P + +
Sbjct: 10577 PPPEVPEAPKEVVPEKK------VPAAPPKKPEVTPVKVPEAPKEVVPEKKVPV 10624
Score = 43.9 bits (102), Expect = 0.002
Identities = 96/446 (21%), Positives = 142/446 (31%), Gaps = 70/446 (15%)
Query: 1796 EAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPP 1855
E E + + P E P P V VP E P + + P +P+ P
Sbjct: 9935 EFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEA-PPAKVPEVPKKPEE-KVPVL 9992
Query: 1856 APRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRR 1915
P+ KVP P V P+P P + +P V P P P ++
Sbjct: 9993 IPKKEKPPPAKVPEVPKKPVPEEKV---PVPVPKKVEAPPAKVPEV--PKKPVPEKKVPV 10047
Query: 1916 PSPLAPRPPPSRWASPPLKTSPQLRVPPPT-SVVTALTPTSGELAPPGPAPSPPPPED-- 1972
P+P PP++ P K P+ + P P V A P + P P P P E+
Sbjct: 10048 PAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEV 10107
Query: 1973 -----LGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEE 2027
+ P+ E + + + + P +EEI EEE
Sbjct: 10108 LFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEI--------------PPEEEE 10153
Query: 2028 SSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSG 2087
P Y+ V + P P P + + + + P+ + PP+
Sbjct: 10154 VPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVI--PKKEEAPPAK 10211
Query: 2088 PGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQ 2147
V V + E LP E+ + P + EE +P PP +
Sbjct: 10212 VPEVPKKVEEKRIILPKEEEVLPVEVTE-------EPEEEPIS--EEEIPEEPPSIEEVE 10262
Query: 2148 PSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPE----PPKPATSKIILVNKLGQVFVK 2203
A P P +P AP P P+ PP + KI
Sbjct: 10263 E----VAPPRVPEVIKKAVPEAPT-------PVPKKVEAPPAKVSKKI------------ 10299
Query: 2204 MAGEGEPVPPPVKQPPLPPTISPTAP 2229
E VP PV++ PP P P
Sbjct: 10300 ---PEEKVPVPVQKKEAPPAKVPEVP 10322
Score = 40.4 bits (93), Expect = 0.024
Identities = 111/566 (19%), Positives = 191/566 (33%), Gaps = 78/566 (13%)
Query: 379 EEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSP 438
E + E E+ ++ + +L PP + P P P P PP + PPV
Sbjct: 8910 EPRGEARSTAELYLTTKEIKLELKPPDI--PDSRVPIPTMPIRAVPPEEI-----PPVVA 8962
Query: 439 PPLPSPPPPPAQEEQEESPPP----VVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSP 494
PP+P P P +E+ PPP V + + P + RE P
Sbjct: 8963 PPIPLLLPTP----EEKKPPPKRIEVTKKAVKKDAKKVVAKPKEMTPREEIVKKP----- 9013
Query: 495 PTPTPSTATGGPPEDSPTVAPKS------TTFLKNIRQFIMPVVSARSSRVIKTPRRFMD 548
P P+T + V+ K+ T K Q V + V K R F++
Sbjct: 9014 --PPPTTLIPAKAPEIIDVSSKAEEVKIMTITRKKEVQKEKEAVYEKKQAVHKEKRVFIE 9071
Query: 549 EDPPKPPKVEVSPVLRP---PITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILR 605
++EV P P P P E V + + E + R
Sbjct: 9072 SFEEPYDELEVEPYTEPFEQPYYEEPDEDYEEIKVEA--KKEVHEEWEEDFEEGQEYYER 9129
Query: 606 EPTF-----RWTSLTRELP---------------PPPPAPPPPPAPSPPPAPATSSRRPL 645
E + W +E P P AP PP ++P+
Sbjct: 9130 EEGYDEGEEEWEEAYQEREVIQVQKEVYEESHERKVPAKVPEKKAPPPPKV----IKKPV 9185
Query: 646 LLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPE-PEPPPADDSPAEPEPRAVGRTNHLSL 704
+ + + + K+ V P + P+ P P + E + AV T + +
Sbjct: 9186 IEKIEKTSRRMEEEKV--QVTKVPEVSKKIVPQKPSRTPVQEEVIEVKVPAV-HTKKMVI 9242
Query: 705 PRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQ-PQLQPP 763
+ + EVS P+ Q +++ + + + + PPP+ P+L
Sbjct: 9243 SEEKMFFASHTEEEVS-------VTVPEVQKEIVTE-EKIHVAISKRVEPPPKVPELPEK 9294
Query: 764 PSPQQMPPLE-----KARIAGVGSLPLSGV--EEKMFSLLKRAKVQLFKIDQQQQQKVAA 816
P+P+++ P+ + V +P V E+K + K+ K+ + ++ V
Sbjct: 9295 PAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPE 9354
Query: 817 SMPLSPGGQMEEVAGAVKQISDRGPVRSEDESVEAKRERPSGPESPVQGPRIKHVCRHAA 876
P + +E A +G V E ++ +RE P P + P+ K
Sbjct: 9355 EKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVP-EIPKKKVPEERKP 9413
Query: 877 VALGQARAMVPEDVPRLSALPLRDRQ 902
V + P VP L P+ + +
Sbjct: 9414 VPRKEEEVPPPPKVPALPKKPVPEEK 9439
Score = 36.6 bits (83), Expect = 0.35
Identities = 55/256 (21%), Positives = 84/256 (32%), Gaps = 52/256 (20%)
Query: 2186 PATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPV 2245
P K I+ + V + E P P + + P P ++P PP P + +P
Sbjct: 9262 PEVQKEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPK 9321
Query: 2246 VGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGE 2305
V P P P PA+PP +V V P P P + + +
Sbjct: 9322 KPVPEEKKPVPVP------KKEPAAPP----KVPEV-------PKKPVPEEKIPVPVAKK 9364
Query: 2306 ASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLPLPEDG 2365
+VP + G + ++ T R EESP P P +PE+
Sbjct: 9365 KEAPPAKVPEVQKGVVTEEKITIVTQR-------------EESPPPAVPEIPKKKVPEER 9411
Query: 2366 PPQVPDGPPDLLLESQWHHYSGEASSSEEEPPSPDDKENQAPKRTGPHLRFEISSEDGFS 2425
P VP EE PP P K PK+ P + +
Sbjct: 9412 KP-VP-------------------RKEEEVPPPP--KVPALPKKPVPEEKVAVPVPVAKK 9449
Query: 2426 VEAESLEGAWRTLIEK 2441
E + +T++E+
Sbjct: 9450 APPPRAEVSKKTVVEE 9465
Score = 35.4 bits (80), Expect = 0.77
Identities = 32/111 (28%), Positives = 46/111 (41%), Gaps = 18/111 (16%)
Query: 151 GRGRKHKTTPLPPPRLADVAPTPPKTPARKR-GEEGTERMVQALTELLRRAQAPQAPRSR 209
G+ HKT P PP+ +PTPP A+ + + + ++ +R +AP R
Sbjct: 246 GQQLPHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIRHSPSPVRHVRAPTPSPVR 305
Query: 210 ACEP-----STPRRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPP 255
+ P ++P RS P RK QA VA PE PPP
Sbjct: 306 SVSPAARISTSPIRSVRSP------LLMRKTQASTVATG------PEVPPP 344
Score = 35.0 bits (79), Expect = 1.0
Identities = 35/159 (22%), Positives = 53/159 (33%), Gaps = 10/159 (6%)
Query: 365 EEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSP 424
E + E+K + + A E ++ A ++ PP PP P P PP +
Sbjct: 215 ESRQTRIEKKIEAHFDARSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPPSIAAK 274
Query: 425 PPPLCPPPPPPVSPPPLP-----SPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQR 479
P P+ P P +P P P + P +T + R PL ++
Sbjct: 275 AQLARQQSPSPIRHSPSPVRHVRAPTPSPVRSVS----PAARISTSPIRSVRSPLL-MRK 329
Query: 480 AEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKST 518
+ GPE P A+ E T ST
Sbjct: 330 TQASTVATGPEVPPPWKQEGYVASSSEAEMRETTLTTST 368
Score = 34.3 bits (77), Expect = 1.7
Identities = 47/202 (23%), Positives = 71/202 (35%), Gaps = 15/202 (7%)
Query: 2179 PAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLP--- 2235
P P+ + +K+ V K + V + + PPP K P +P P +P
Sbjct: 9966 PVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKV 10025
Query: 2236 --PGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPP 2293
P + +P V P P P + P++ I ++ T + APP
Sbjct: 10026 EAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPP 10085
Query: 2294 PYKAPRLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQ 2353
P K P+ E PQ V + V L E EE L
Sbjct: 10086 P-KVPKKREPVPVPVALPQE--------EEVLFEEEIVPEEEVLPEEEEVLPEEEE-VLP 10135
Query: 2354 ERSPLLPLPEDGPPQVPDGPPD 2375
E +LP E+ PP+ + PP+
Sbjct: 10136 EEEEVLPEEEEIPPEEEEVPPE 10157
Score = 33.9 bits (76), Expect = 2.2
Identities = 27/82 (32%), Positives = 33/82 (40%), Gaps = 9/82 (10%)
Query: 579 PVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPP---APPPPPAPSPPP 635
P +PPR P P + P P + + + S R P P AP P P S P
Sbjct: 250 PHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIRHSPSPVRHVRAPTPSPVRSVSP 309
Query: 636 A------PATSSRRPLLLRAPQ 651
A P S R PLL+R Q
Sbjct: 310 AARISTSPIRSVRSPLLMRKTQ 331
Score = 32.7 bits (73), Expect = 5.0
Identities = 27/113 (23%), Positives = 46/113 (40%), Gaps = 4/113 (3%)
Query: 2187 ATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVV 2246
AT ++++ GQ P P P + P PP+I+ A + P P+ V
Sbjct: 235 ATVEMVIDGAAGQQLPHKTPPRIP-PKPKSRSPTPPSIAAKAQLARQQSPSPIRHSPSPV 293
Query: 2247 GVVRPAPPPPPPPLTLV--LSSGPASPPRQAIRVKRVSTFS-GRSPPAPPPYK 2296
VR P P ++ +S+ P R + +++ + P PPP+K
Sbjct: 294 RHVRAPTPSPVRSVSPAARISTSPIRSVRSPLLMRKTQASTVATGPEVPPPWK 346
Score = 32.7 bits (73), Expect = 5.0
Identities = 31/93 (33%), Positives = 40/93 (43%), Gaps = 12/93 (12%)
Query: 541 KTPRRFMDEDP---PKPPKVEVSPVLR-----PPITTSP-PVPQEPAPVPSPPRAPTPPS 591
KTP R + P PP + L PI SP PV AP PSP R+ +P +
Sbjct: 252 KTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIRHSPSPVRHVRAPTPSPVRSVSPAA 311
Query: 592 --TPVPLPEKRRSILREPTFRWTSLT-RELPPP 621
+ P+ R +L T T T E+PPP
Sbjct: 312 RISTSPIRSVRSPLLMRKTQASTVATGPEVPPP 344
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 114 bits (286), Expect = 1e-24
Identities = 123/456 (26%), Positives = 169/456 (37%), Gaps = 64/456 (14%)
Query: 408 PPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPS---------PPPPPAQEEQEESPP 458
P P PPPPLPPP PPPL PPPPP S PP+ + P A +
Sbjct: 2 PVPPPPPPPLPPP----PPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGT 57
Query: 459 PVVPATCSRKRGRPPLTPSQRAERE-AARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKS 517
+ T R P + S+ +E A G S P GG P + P
Sbjct: 58 RLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGG----FPVLRPAG 113
Query: 518 TTFLKNIRQFIMPVVSARSSRVIKTPRRFMDED--PPKPPKVEVSPVLRPPITTSPPVPQ 575
+ + P A S R+ P + + PP P++ + T+PP P
Sbjct: 114 QRDVAGGKTGQGPGSRAPSPRL---PNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPN 170
Query: 576 EPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTF---------RWTSLTRELPPPPPAPP 626
PAP PP P PP P+P P S ++ P + +P PP PP
Sbjct: 171 VPAP---PPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPP 227
Query: 627 PPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHL-KIYESVLTPPPLGAPEAPEPEPPPAD 685
PPP P+PPP P S ++ PQ P HL I + PP G P PA
Sbjct: 228 PPPPPTPPPLPPASVLSDKAVK-PQLAP--LHLPPIPPPLPLLPPCGYPGLKAEPASPAQ 284
Query: 686 DSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQL---LQPLQ 742
D+ P P P P + +A + P +++ +T L Q
Sbjct: 285 DAQEPPAPP----------PPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQ 334
Query: 743 ALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGVGSLPLSGVEEKMFSLLKRAKVQ 802
A + QALP PP P P L+K R P +G + A+
Sbjct: 335 APPQKAGAQALP------APPAPPGSQPFLQKKR----HGRPGAGGGKLNPPPAPPARSP 384
Query: 803 LFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISD 838
++ + QQ A + PGGQ+ G++ I D
Sbjct: 385 TTELSSKSQQATAWTPTQQPGGQLRN--GSLHIIDD 418
Score = 85.5 bits (210), Expect = 6e-16
Identities = 105/371 (28%), Positives = 126/371 (33%), Gaps = 87/371 (23%)
Query: 2055 APRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAG--VLGAAGDRARPPEDLPSE 2112
AP+IE GT+ E RG TPP+ + G VL AG R D+
Sbjct: 70 APQIES----SKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQR-----DVAGG 120
Query: 2113 IVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGV 2172
K GPG PR + + PL + P G T+ RT P P V
Sbjct: 121 ------KTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAART---APPRPNV 171
Query: 2173 RVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSW 2232
PAP PP P PPP PPLPP + ++P
Sbjct: 172 ------PAPPPPTPP------------------------PPP---PPLPPPLPSSSPIKT 198
Query: 2233 TL--PPGPLL-GVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSG--R 2287
L PPGPL G LPVV P PPPPPP + P PP + K V
Sbjct: 199 PLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPP--PPTPPPLPPASVLSDKAVKPQLAPLH 256
Query: 2288 SPPAPPP-----------YKAPRLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLD 2336
PP PPP KA +A E P L R P
Sbjct: 257 LPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAP----- 311
Query: 2337 LDRPGEPAGEESPGPLQERSPLLPLPED--------GPPQVPDGPPDLLLESQWHHYSGE 2388
PG + E+P PL +SP P PP P P L+ + H G
Sbjct: 312 -PLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQP--FLQKKRHGRPGA 368
Query: 2389 ASSSEEEPPSP 2399
PP+P
Sbjct: 369 GGGKLNPPPAP 379
Score = 84.0 bits (206), Expect = 2e-15
Identities = 84/295 (28%), Positives = 107/295 (36%), Gaps = 88/295 (29%)
Query: 393 AAEKEEAKLPPPPLTPPAPSP-PPPLP------PPSTSPPPPLCP------PPPPPVSPP 439
A + PPPP PP P P PPPLP P SPP PL PP P +PP
Sbjct: 165 APPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPP 224
Query: 440 PLPSPPPPPAQEEQEESPPPVVPAT-CSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPT 498
P P PPPP +PPP+ PA+ S K +P L P PP P
Sbjct: 225 PPPPPPPP--------TPPPLPPASVLSDKAVKPQLAPLH--------------LPPIPP 262
Query: 499 PSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVE 558
P P + P LK P A+ + ++PP PP
Sbjct: 263 P----------LPLLPPCGYPGLK-----AEPASPAQDA-----------QEPPAPP--- 293
Query: 559 VSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTREL 618
P L P + S P+ P P P + TP PLP K S + P + +
Sbjct: 294 --PPLPPYASCS---PRASLPAPPLPGVNSSSETPPPLPPKSPS-FQAPPQKAGAQALPA 347
Query: 619 PPPPPAPPP-----------------PPAPSPPPAPATSSRRPLLLRAPQFTPSE 656
PP PP P P P+PP T+ +A +TP++
Sbjct: 348 PPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQATAWTPTQ 402
Score = 60.8 bits (146), Expect = 2e-08
Identities = 42/128 (32%), Positives = 54/128 (42%), Gaps = 15/128 (11%)
Query: 387 AEEMMPAAEKEEAKLPPPPL------TPPAPSPPPPLP-PPSTSPPPPLCPPPPPPVSPP 439
AE PA + +E PPPPL +P A P PPLP S+S PP PP P P
Sbjct: 277 AEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAP 336
Query: 440 P-------LPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGT 492
P LP+PP PP + + P K PP P++ E + + T
Sbjct: 337 PQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQAT 396
Query: 493 S-PPTPTP 499
+ PT P
Sbjct: 397 AWTPTQQP 404
Score = 56.2 bits (134), Expect = 4e-07
Identities = 92/368 (25%), Positives = 129/368 (35%), Gaps = 64/368 (17%)
Query: 1811 SSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPNY 1870
S+ G PP D+ G P LRP +G ++ G + P+
Sbjct: 86 SANTRGASTPPTLGDLFAGGFPV-----------LRP-AGQRDVAGGKTGQGPGSRAPS- 132
Query: 1871 SPSRRPLGGVSFGPLPSPGSP----SSLTHHIPTVGDPDFPAPPRRSRRPSPLAPR-PPP 1925
R P +S GPL P SP +S H APPR + P+P P PPP
Sbjct: 133 --PRLPNKTIS-GPLIPPASPRLGNTSEAHGAART------APPRPNV-PAPPPPTPPPP 182
Query: 1926 SRWASPPLKTSPQLRVP---PPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEV 1982
PPL +S ++ P PP + P P P P PPPP P V
Sbjct: 183 PPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASV 242
Query: 1983 VSGLSAADLDFAASLLGTEPFQEEIVAAGAMG--SSHGGPGDSSEEESSPTSRYIHFPVT 2040
+S + L P + G G + P ++E +P P
Sbjct: 243 LSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAP-------PPP 295
Query: 2041 VVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAG 2100
+ +P A+ AP L GV+ +++ + PP AG
Sbjct: 296 LPPYASCSPRASLPAP---PLPGVNSSSETPPPLPPKSPSFQAPPQ-----------KAG 341
Query: 2101 DRARPPEDLPSEIVDFVLKNL-GGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADP 2159
+A P P F+ K G PG GG + + PPAPP P+ L++
Sbjct: 342 AQALPAPPAPPGSQPFLQKKRHGRPGAGGG---KLNPPPAPP---ARSPTTELSSKSQQA 395
Query: 2160 TRTFAWLP 2167
T AW P
Sbjct: 396 T---AWTP 400
Score = 52.8 bits (125), Expect = 5e-06
Identities = 66/274 (24%), Positives = 93/274 (33%), Gaps = 52/274 (18%)
Query: 1808 PAPSSEPPGGEDPPLDTDVLVPGAPERHS-------PIQNLDPPLRPDSGSAPPP-APRS 1859
P P PP P+ T ++ P P P+ PP P PPP P S
Sbjct: 182 PPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPAS 241
Query: 1860 FSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPL 1919
+ P +P P P+P P +P G P A P + +
Sbjct: 242 VLSDKAVKPQLAPLHLP-------PIPPP------LPLLPPCGYPGLKAEPASPAQDAQE 288
Query: 1920 APRPPPSRWASPPLKTSPQLRVP-PPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFE 1978
P PPP P SP+ +P PP V + + T L P P+ PP +
Sbjct: 289 PPAPPPP--LPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQK------- 339
Query: 1979 DMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFP 2038
A L + G++PF ++ HG PG + + P + P
Sbjct: 340 -------AGAQALPAPPAPPGSQPFLQK--------KRHGRPGAGGGKLNPPPAPPARSP 384
Query: 2039 VTVVS-----APGLAPSATPGAP-RIEQLDGVDD 2066
T +S A P+ PG R L +DD
Sbjct: 385 TTELSSKSQQATAWTPTQQPGGQLRNGSLHIIDD 418
Score = 48.9 bits (115), Expect = 7e-05
Identities = 60/218 (27%), Positives = 77/218 (35%), Gaps = 42/218 (19%)
Query: 2210 PVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPA 2269
PVPPP P PP LPP P P +G P PP PP T S A
Sbjct: 2 PVPPP----PPPP-----------LPPPP-----PPLGAPPPPPPSAPPVSTDTSSLRRA 41
Query: 2270 SPP---------RQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEA----SEDTPQVPGL 2316
P +Q R+++V+ + RS P K + G A + P + L
Sbjct: 42 DPKGRSALLADIQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDL 101
Query: 2317 GSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLPLPEDGPPQVPDGPPDL 2376
+GGF P +R D G G + PG + SP LP P +P P L
Sbjct: 102 FAGGF-------PVLRPAGQRDVAGGKTG-QGPGS-RAPSPRLPNKTISGPLIPPASPRL 152
Query: 2377 LLESQWHHYSGEASSSEEEPPSPDDKENQAPKRTGPHL 2414
S+ H + A P P P P L
Sbjct: 153 GNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPL 190
Score = 39.3 bits (90), Expect = 0.053
Identities = 64/248 (25%), Positives = 78/248 (31%), Gaps = 46/248 (18%)
Query: 2185 KPATSKIILVNKLGQVFVKMAGEGEPVPPP------VKQPPLPPTISPTAPTSW------ 2232
+PA + + K GQ G G P P + P +PP TS
Sbjct: 110 RPAGQRDVAGGKTGQ------GPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAAR 163
Query: 2233 TLPPGPLLGVLPVVGVVRPAPPPP--PPPL--------TLVLSSGPASPPRQAIRVKRVS 2282
T PP P + P P PPPP PPPL LV GP + + V
Sbjct: 164 TAPPRPNV---PAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVP 220
Query: 2283 TFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGE 2342
PP PPP P D P L + P + E
Sbjct: 221 CAPPPPPPPPPPTPPPL--PPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAE 278
Query: 2343 PA--GEESPGPLQERSPLLPLPEDGPPQVPDGPPDLLLESQWHHYSGEASSSEEEPPSPD 2400
PA +++ P PL P P PP G SSSE PP P
Sbjct: 279 PASPAQDAQEPPAPPPPLPPYASCSPRASLPAPP----------LPGVNSSSETPPPLPP 328
Query: 2401 DKEN-QAP 2407
+ QAP
Sbjct: 329 KSPSFQAP 336
Score = 33.9 bits (76), Expect = 2.2
Identities = 39/150 (26%), Positives = 50/150 (33%), Gaps = 26/150 (17%)
Query: 141 LRSQRGRAPRGRGRKHKTTPLPPPRLADV--APTPPKTPARKRGEEGTERMVQALTELLR 198
+ S +G G G + PP L D+ P PA +R G
Sbjct: 73 IESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAG------------- 119
Query: 199 RAQAPQAPRSRACEPSTPRRSRGRPPGRPAGP-CRRKQQAVVVAEAAVTIPK-------- 249
+ Q P SRA P P ++ P PA P +A A A P
Sbjct: 120 -GKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPT 178
Query: 250 -PEPPPPVVPVKHQTGSWKCKEGPGPGPGT 278
P PPPP+ P + K PGP T
Sbjct: 179 PPPPPPPLPPPLPSSSPIKTPLVSPPGPLT 208
Score = 32.0 bits (71), Expect = 8.5
Identities = 51/210 (24%), Positives = 75/210 (35%), Gaps = 26/210 (12%)
Query: 59 AEPGEDTALLRLLGLRRGLRRLRRL--WAGPRVQRGRGRGR-GRGWGPSRGCVPEEESSD 115
A+P +ALL + LR++ ++ + P+++ +G + G G +RG D
Sbjct: 41 ADPKGRSALLADIQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGD 100
Query: 116 GESDEEEFQGFHSDEDVAPSSLRSALRSQRGRAPRGRGRKHKTTPLPPPRLADVAPTPPK 175
+ GF + P+ R + G+ P R P PRL + + P
Sbjct: 101 LFAG-----GFPV---LRPAGQRDVAGGKTGQGPGSRA--------PSPRLPNKTISGPL 144
Query: 176 TP-ARKRGEEGTERMVQALTELLR-RAQAPQAPRSRACEPSTPRRSRGRPPGR-----PA 228
P A R +E A T R AP P P P P + P
Sbjct: 145 IPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPP 204
Query: 229 GPCRRKQQAVVVAEAAVTIPKPEPPPPVVP 258
GP + VV P P PPPP P
Sbjct: 205 GPLTKGNLPVVAPPVPCAPPPPPPPPPPTP 234
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 112 bits (279), Expect = 6e-24
Identities = 114/431 (26%), Positives = 161/431 (37%), Gaps = 58/431 (13%)
Query: 357 QEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMM--PAAEKEEAKLPPPPLTPPAPSPP 414
++ D +E+ +E + E ++ A +++ P + E P TP P+P
Sbjct: 160 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPT 219
Query: 415 PPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPL 474
P P ST+P P P S P P P P + +P P T P
Sbjct: 220 TPKEPASTTPKEPT---PTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK 276
Query: 475 TPSQRAEREAARAGPEG--TSPPTPTPST----ATGGPPEDSPTVAPKSTTFLKNIRQFI 528
P+ +E A + T+P P P+T A P E +PT PK T
Sbjct: 277 EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPT-TPKEPT--------- 326
Query: 529 MPVVSARSSRVIKTPRRFMDEDP-PKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAP 587
P + K P ++P P PK P P +P P+EPAP + +P
Sbjct: 327 -PTTPKEPAPTTKEPAPTTPKEPAPTAPK---KPAPTTPKEPAPTTPKEPAPTTTKEPSP 382
Query: 588 TPPSTPVPLPEKRR-SILREPTFRWTSLTRELPPPPPAPPP----PPAPSPPPAPA-TSS 641
T P P P K + +EP + T+ P P P P PAP+ P PA T+
Sbjct: 383 TTPKEPAPTTTKSAPTTTKEPA---PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP 439
Query: 642 RRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPE-APEPEPPPADDSPAEPEPRAVGRTN 700
++P AP TP E P P E AP PA +P EP P T
Sbjct: 440 KKP----APT-TPKE-----------PAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 483
Query: 701 HLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQL 760
+ + P TTP K + PA P T +L T P+ P P+
Sbjct: 484 PTTPKKLTP--TTPEKLAPTTPEKPA----PTTPEELAPTTPEEPTPTTPEEPAPTTPKA 537
Query: 761 QPPPSPQQMPP 771
P +P++ P
Sbjct: 538 AAPNTPKEPAP 548
Score = 112 bits (279), Expect = 6e-24
Identities = 168/746 (22%), Positives = 240/746 (32%), Gaps = 168/746 (22%)
Query: 140 ALRSQRGRAPRGRGRKHKTTPLPP-PRLADVAPTPPKTPARKRGEEGTERMVQALTELLR 198
AL + + P TTP P P APT PK PA +
Sbjct: 209 ALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTK--------------- 253
Query: 199 RAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVP 258
AP P+ A P+T + P PA P K+ A ++A T PK P P P
Sbjct: 254 --SAPTTPKEPA--PTTTKEPAPTTPKEPA-PTTTKEPAPTTTKSAPTTPK--EPAPTTP 306
Query: 259 VKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGGLPFVIKFVSRAKKVKMGQ 318
K P P TP+ ++
Sbjct: 307 KK-------------PAPTTPKEPAPTT-------------------------------- 321
Query: 319 LSLGLESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQKLDDEEEEKKEEEEKDKEG 378
+E P+ + + +P K+ ++ +E
Sbjct: 322 -------------PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 368
Query: 379 EEKEERAVAEEMMPAAEKEEA-----------KLPPPPLTPPAPSPPPPLPPPSTSPPPP 427
++ +E P KE A K P P T AP+ P P +T P P
Sbjct: 369 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 428
Query: 428 LCPPPPPPVSP-PPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAAR 486
P P P +P P P+ P PA +E P T ++K P+ +E A
Sbjct: 429 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP-----TTTKK-------PAPTTPKEPAP 476
Query: 487 AGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRF 546
P+ T+P TP T T P + +PT K TP
Sbjct: 477 TTPKETAPTTPKKLTPT-TPEKLAPTTPEKPAP---------------------TTPEEL 514
Query: 547 MDEDPPKP-PKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILR 605
P +P P P P +P P+EPAP APT P P P K
Sbjct: 515 APTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKE----- 569
Query: 606 EPTFRWTSLTRELPPPPPAPP--PPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYE 663
T P AP PAP+ P PA P + P T + +
Sbjct: 570 ---------TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD------K 614
Query: 664 SVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHG 723
T P AP P+ PA +P EP P T +L AP TTP K
Sbjct: 615 PAPTTPKGTAPTTPK---EPAPTTPKEPAPTTPKGTAPTTLKEPAP--TTP-KKPAPKEL 668
Query: 724 APALSNGP-QTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGVGS 782
AP + GP T + P +T P P +P P+ + PP + + S
Sbjct: 669 APTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEV----S 724
Query: 783 LPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISDRGPV 842
P + E ++ K ++ + K + P PG + A K
Sbjct: 725 TPTTTKEPT--TIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATK---PEMTT 779
Query: 843 RSEDESVEAKRERPSGPESPVQGPRI 868
++D++ E R+ + PE+ P++
Sbjct: 780 TAKDKTTE--RDLRTTPETTTAAPKM 803
Score = 111 bits (277), Expect = 1e-23
Identities = 143/586 (24%), Positives = 205/586 (34%), Gaps = 77/586 (13%)
Query: 130 EDVAPSSLRSALRSQRGRAPRGRGRKHKTTPLPPPRLA-DVAPTPPKTPARKRGEEGTER 188
++ P++++SA + + AP T P P + APT PK PA +E
Sbjct: 230 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPT 289
Query: 189 MVQALTELLRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIP 248
++ + AP P+ A P+TP+ P P P K+ A E A T P
Sbjct: 290 TTKS-APTTPKEPAPTTPKKPA--PTTPKEPAPTTPKEPT-PTTPKEPAPTTKEPAPTTP 345
Query: 249 KPEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGGLPFVIKFV 308
K P P P K + K P P TP+ P K
Sbjct: 346 KE--PAPTAPKKPAPTTPK-----EPAPTTPKEPA------------------PTTTKEP 380
Query: 309 SRAKKVKMGQLSLGLESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQKLDDEEEEK 368
S + + +S + + +P K+ +E
Sbjct: 381 SPTTPKEPAPTTT------------KSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 428
Query: 369 KEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSP--PP 426
+E +K +E P KE A P P P P P T+P P
Sbjct: 429 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK 488
Query: 427 PLCPPPPPPVSP--PPLPSPPPP----PAQEEQEESPPPVVPATCSRKRGRP--PLTPSQ 478
L P P ++P P P+P P P E+ P PA + K P P P+
Sbjct: 489 KLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP 548
Query: 479 RAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTV--APKSTTFLKNIRQFIMPVVSARS 536
+E A P+ +P TP TA P +PT P TT K + + P +
Sbjct: 549 TTPKEPAPTTPKEPAPTTP-KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEP 607
Query: 537 SRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPL 596
+ D+ P PK + P +P P+EPAP APT P P
Sbjct: 608 TSTT------CDKPAPTTPKGTAPTTPKEP---APTTPKEPAPTTPKGTAPTTLKEPAPT 658
Query: 597 PEKR---RSILREPTFRWTSLTRELPPP------PPAPPPPPAPSPPPAPA-TSSRRPLL 646
K+ + + T TS T + P P P P PAP+ P PA T+ P
Sbjct: 659 TPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPP 718
Query: 647 LRAPQFTPSEAHLKIYESVLTPPPLGAPE-APEPEPPPADDSPAEP 691
+ TP+ K ++ P PE + EP P ++SP EP
Sbjct: 719 TTSEVSTPTTT--KEPTTIHKSPDESTPELSAEPTPKALENSPKEP 762
Score = 110 bits (274), Expect = 2e-23
Identities = 137/577 (23%), Positives = 188/577 (32%), Gaps = 56/577 (9%)
Query: 388 EEMMPAAEKEEAKLPPPPLTPP----APSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPS 443
+E P KE A P TP AP+ P P +T P P P + P P+
Sbjct: 214 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 273
Query: 444 PPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTAT 503
P PA +E P + + + P TP + A P T+P PTP+T
Sbjct: 274 TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP--TTPKEPTPTT-- 329
Query: 504 GGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVL 563
P E +PT + T K P +A TP+ E P PK
Sbjct: 330 --PKEPAPTTKEPAPTTPKE------PAPTAPKKPAPTTPK----EPAPTTPKEPAPTTT 377
Query: 564 RPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRR-SILREPTFRWTSLTRELPPPP 622
+ P SP P+EPAP + APT P P K + +EP+ T P
Sbjct: 378 KEP---SPTTPKEPAPT-TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 433
Query: 623 PAP--PPPPAPSPPPAPA-TSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEP 679
PAP P PAP+ P PA T+ + P AP T A E T P AP P+
Sbjct: 434 PAPTTPKKPAPTTPKEPAPTTPKEP----APTTTKKPAPTTPKEPAPTTPKETAPTTPKK 489
Query: 680 EPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQ 739
P + A P T L P TP P+ A
Sbjct: 490 LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTT--------------PEEPAPTTP 535
Query: 740 PLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGVGSLPLSGVEEKMFSLLKRA 799
A T P P +P P P P E A G+ P + E + K A
Sbjct: 536 KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA 595
Query: 800 KVQLFKIDQQQQQKVAAS--MPLSPGGQMEEVAGAVKQISDRGPVRSEDESVEAKRERPS 857
+L ++ P +P G + + P + + +
Sbjct: 596 PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEP 655
Query: 858 GPESPVQGPRIKHVCRHAAVALGQARAMVPEDVPRLSALPLRDRQDLATEDTSSASETES 917
P +P + P K + + P P ++ T A T
Sbjct: 656 APTTP-KKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPE 714
Query: 918 VPSRSRRGKVEAAGPGGESEPTGSGGTLAHTPRRSLP 954
P + E + P EPT T+ +P S P
Sbjct: 715 TPPPTTS---EVSTPTTTKEPT----TIHKSPDESTP 744
Score = 98.2 bits (243), Expect = 1e-19
Identities = 106/423 (25%), Positives = 152/423 (35%), Gaps = 59/423 (13%)
Query: 367 EKKEEEEKDKE-GEEKEERAVAEEMMPAAEKEEAK-LPPPPLTPPAPSPPPPLPPPSTSP 424
E KE +K+ + +E+ + + + EK AK L P P+P +
Sbjct: 151 ETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPAL 210
Query: 425 PPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREA 484
P P P P P P P + + P T ++ P P+ +E
Sbjct: 211 TTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP 270
Query: 485 ARAGPEGTSPPT---PTPSTATGGP--PEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRV 539
A P+ +P T P P+T P P++ PK P +
Sbjct: 271 APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK------------PAPTTPKEPA 318
Query: 540 IKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEK 599
TP+ E P PK E +P + P +P P+EPAP APT P P P K
Sbjct: 319 PTTPK----EPTPTTPK-EPAPTTKEP---APTTPKEPAPTAPKKPAPTTPKEPAPTTPK 370
Query: 600 RRSILREPTFRWTSLTRELPPPPPAPPPP------PAPSPPPAPATSSRRPLLLRAPQFT 653
EP + T+E P P P P P + PAP T+ P + P T
Sbjct: 371 ------EPA---PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPT 421
Query: 654 PSEAHLKIYESVLTPPPLGAPEAPEPEPP-----PADDSPAEPEPRAVGRTNHLSLPRFA 708
++ E T P AP P+ P PA +P EP P + + A
Sbjct: 422 TTK------EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 475
Query: 709 PVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQ 768
P TTP E +P L+ P T +L P+ L P P+ P +P++
Sbjct: 476 P--TTP--KETAPTTPKKLT--PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE 529
Query: 769 MPP 771
P
Sbjct: 530 PAP 532
Score = 74.7 bits (182), Expect = 1e-12
Identities = 111/488 (22%), Positives = 162/488 (33%), Gaps = 70/488 (14%)
Query: 157 KTTPLPPPRLADVAPTPPKTPARKRGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTP 216
K TP P +LA PT P+ PA EE + T AP P++ A P+TP
Sbjct: 489 KLTPTTPEKLA---PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA--PNTP 543
Query: 217 RRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGP 276
+ P PA ++ E A T PK P + KE P P
Sbjct: 544 KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTL------------KE---PAP 588
Query: 277 GTPRRGGQSSRGGRGGRGRGRGGGLPFVIKFVSRAKKVKMGQLSLGLESGQGQGQHEESW 336
TP++ P K + K + G +E
Sbjct: 589 TTPKKPAPKELA-------------PTTTKEPTSTTCDKPAPTT---PKGTAPTTPKEPA 632
Query: 337 QDVPQRRVGSG-QGGSPCWKKQEQKLDDEEEEKKEEEEKDKEG-----EEKEERAVAEEM 390
P+ + +G +P K+ ++ KE +G +K +E
Sbjct: 633 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 692
Query: 391 MPAAEKEEAKLPPPPLTPPAPSPPPP-LPPPSTSP-------PPPLCPPPPPPVSPPPLP 442
P KE P P TP P+P P PPP+TS P P S P L
Sbjct: 693 APTTPKE-----PAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELS 747
Query: 443 SPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQR---AEREAARAGPEGTSPPTPTP 499
+ P P A E + P VP T + +P +T + + ER+ T+ P T
Sbjct: 748 AEPTPKALENSPKEPG--VPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTK 805
Query: 500 STATGGPPEDSPTVAPKSTTFLKNIRQFIMPV------VSARSSRVIKTPRRFMDEDPPK 553
TAT + +T Q P + + +V T + +
Sbjct: 806 ETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMN 865
Query: 554 PPKVEVSPVLRPPIT-TSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWT 612
P+ P R + + P PQ+P P P + P T +P R+ + T
Sbjct: 866 KPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKT---MPRVRKPKTTPTPRKMT 922
Query: 613 SLTRELPP 620
S EL P
Sbjct: 923 STMPELNP 930
Score = 72.4 bits (176), Expect = 6e-12
Identities = 142/647 (21%), Positives = 198/647 (30%), Gaps = 87/647 (13%)
Query: 1797 AAEENQTIVHSPA----PSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSA 1852
+A+E Q+I + A P+S+ P +T P P P P S +
Sbjct: 172 SAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTT--PKEPASTTP 229
Query: 1853 PPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPA---- 1908
P P + A P P S P +P++ PT P
Sbjct: 230 KEPTPTTIKSA----PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKE 285
Query: 1909 PPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPP 1968
P + + +P P+ P P T+P + P PT+ T E AP P+P
Sbjct: 286 PAPTTTKSAPTTPKEPAPTTPKKPAPTTP--KEPAPTTPKEPTPTTPKEPAPTTKEPAPT 343
Query: 1969 PPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEES 2028
P++ P A EP ++ P ++ +E
Sbjct: 344 TPKEPAPTAPKKP-------------APTTPKEPAP----------TTPKEPAPTTTKEP 380
Query: 2029 SPTSRYIHFPVTVVSAPGL----APSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTP 2084
SPT+ P T SAP AP+ T AP + + ++P T
Sbjct: 381 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP--TT 438
Query: 2085 PSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGG--PGDGGAGPREESLPPAPPL 2142
P P A P P E K P + +E+ P P
Sbjct: 439 PKKP---------APTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKK 489
Query: 2143 ANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFV 2202
+ P + +P P T AP PE P P T K N
Sbjct: 490 LTPTTPEKLAPTTPEKPAPTTPE-ELAPTTPEEPTPTTPEEPAPTTPKAAAPN------- 541
Query: 2203 KMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTL 2262
E P P P P +PT P T P P G P + PAP P P
Sbjct: 542 -TPKEPAPTTPKEPAPTTPKEPAPTTPKE-TAPTTP-KGTAPTT-LKEPAPTTPKKPAPK 597
Query: 2263 VLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDED--------------GEASE 2308
L+ P K T + P P AP ++ E +
Sbjct: 598 ELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP 657
Query: 2309 DTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGE--PAGEESPGPLQERSPLLPLPEDGP 2366
TP+ P + + T T P E P + P P + P PE P
Sbjct: 658 TTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPP 717
Query: 2367 PQVPD-GPPDLLLESQWHHYSGEASSSE-EEPPSPDDKENQAPKRTG 2411
P + P E H S + S+ E P+P EN +PK G
Sbjct: 718 PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALEN-SPKEPG 763
Score = 68.6 bits (166), Expect = 8e-11
Identities = 124/588 (21%), Positives = 178/588 (30%), Gaps = 56/588 (9%)
Query: 1790 EEPAHLEAAEENQTIVHSPAPS---SEPPGGEDPPLDTDVLVPGAPERHSPIQNLDP--- 1843
+EP E T P P+ S P ++P T P P+ +P +P
Sbjct: 214 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 273
Query: 1844 -PLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPS-PGSPSSLTHHIPTV 1901
P P + PAP + A + + P P P+ P P+ T PT
Sbjct: 274 TPKEPAPTTTKEPAPTTTKSAP------TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTP 327
Query: 1902 GDPDFPAP------PRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTS 1955
P PAP P + P+P AP+ P P T+P + P PT+ T
Sbjct: 328 TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTP--KEPAPTTTKEPSPTTP 385
Query: 1956 GELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGS 2015
E AP +P ++ P + + T +
Sbjct: 386 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 445
Query: 2016 SHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAV 2075
+ P ++ +E +PT+ T AP P P+ T + E +
Sbjct: 446 TPKEPAPTTPKEPAPTT-------TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL 498
Query: 2076 QQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREES 2135
+ P+ P + A P P E P A
Sbjct: 499 APTTPEKPAPTTPEEL------APTTPEEPTPTTPEE---------PAPTTPKAAAPNTP 543
Query: 2136 LPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVN 2195
PAP P+ +P P T P L PAP PK K +
Sbjct: 544 KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK-EPAPTTPKKPAPKELAPT 602
Query: 2196 KLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLL--GVLPVVGVVRPAP 2253
+ + P P P P +PT P P P G P + PAP
Sbjct: 603 TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKE----PAPTTPKGTAPTT-LKEPAP 657
Query: 2254 PPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQV 2313
P P L+ P K T + P P AP + + + TP+
Sbjct: 658 TTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPK--KPAPTTPET 715
Query: 2314 PGLGSGGFSR-VRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLP 2360
P + S K PT + E + E +P L E SP P
Sbjct: 716 PPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKAL-ENSPKEP 762
Score = 67.0 bits (162), Expect = 2e-10
Identities = 112/481 (23%), Positives = 162/481 (33%), Gaps = 55/481 (11%)
Query: 1790 EEPAHLEAAEENQTIVHSPAPSSEPPGGEDP----PLDTDVLVPGAPERHSPIQNLDPP- 1844
+EPA E T PAP+++ P P P P P+ +P +P
Sbjct: 315 KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP 374
Query: 1845 ---LRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTV 1901
P + PAP + A P + P S P SP++ PT
Sbjct: 375 TTTKEPSPTTPKEPAPTTTKSA----PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT 430
Query: 1902 GDPDFPAP-------PRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVP--PPTSVVTA-- 1950
P PAP P + P+P P+ P P T+P+ P P + T
Sbjct: 431 --PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK 488
Query: 1951 -LTPTSGE-LAPPGP-APSPPPPEDLGPDF-EDMEVVSGLSAADLDFAASLLGTEPFQEE 2006
LTPT+ E LAP P P+P PE+L P E+ + A A+ T
Sbjct: 489 KLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP 548
Query: 2007 IVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQL--DGV 2064
++ P ++ +E++PT+ P T+ AP+ TP P ++L
Sbjct: 549 TTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP---APT-TPKKPAPKELAPTTT 604
Query: 2065 DDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGP 2124
+ T + + +GT P+ P A P P LK
Sbjct: 605 KEPTSTTCDKPAPTTPKGTAPTTPKE------PAPTTPKEPAPTTPKGTAPTTLKEPAPT 658
Query: 2125 GDGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLP--GAPGVRVLSLGPAPE 2182
P+E AP G + +P P T P AP PE
Sbjct: 659 TPKKPAPKE----LAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPE 714
Query: 2183 PPKPATSKII--LVNKLGQVFVKMAGE------GEPVPPPVKQPPLPPTISPTAPTSWTL 2234
P P TS++ K K E EP P ++ P P + T + T
Sbjct: 715 TPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATK 774
Query: 2235 P 2235
P
Sbjct: 775 P 775
Score = 57.8 bits (138), Expect = 1e-07
Identities = 105/513 (20%), Positives = 165/513 (32%), Gaps = 81/513 (15%)
Query: 1918 PLAPRP--PPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGP 1975
P+ PRP PP+ S L V T+V T T T+ + + ++
Sbjct: 123 PINPRPSLPPNSDTSK----ETSLTVNKETTVETKETTTTNK-------QTSTDGKEKTT 171
Query: 1976 DFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYI 2035
++ + + SA DL + +L + E G ++ P ++ +E + T+
Sbjct: 172 SAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKE 231
Query: 2036 HFPVTVVSAPGL----APSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVV 2091
P T+ SAP AP+ T AP + + ++P T P
Sbjct: 232 PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT 291
Query: 2092 RAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQG 2151
++ P E P+ P++ + P P + P +
Sbjct: 292 KSA-------PTTPKEPAPTT------------------PKKPA-PTTPKEPAPTTPKEP 325
Query: 2152 LTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPV 2211
+P +P T AP AP+ P P T K EP
Sbjct: 326 TPTTPKEPAPTTK--EPAPTTPKEPAPTAPKKPAPTTPK------------------EPA 365
Query: 2212 PPPVKQP-------PLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVL 2264
P K+P P P T APT+ P P P P P P T
Sbjct: 366 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP-TTTK 424
Query: 2265 SSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRV 2324
P +P A + + PAP K P + + TP+ P +
Sbjct: 425 EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP-----TTP 479
Query: 2325 RMKTPTVRGVLDLDRPGE--PAGEESPGPLQERSPLLPLPEDGPPQVPDGPPDLLLESQW 2382
+ PT L P + P E P P PE+ P P+ P ++
Sbjct: 480 KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA 539
Query: 2383 HHYSGEASSSEEEPPSPDDKENQA---PKRTGP 2412
+ E + + + P+P + A PK T P
Sbjct: 540 PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 572
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 112 bits (279), Expect = 6e-24
Identities = 114/431 (26%), Positives = 161/431 (37%), Gaps = 58/431 (13%)
Query: 357 QEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMM--PAAEKEEAKLPPPPLTPPAPSPP 414
++ D +E+ +E + E ++ A +++ P + E P TP P+P
Sbjct: 201 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPT 260
Query: 415 PPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPL 474
P P ST+P P P S P P P P + +P P T P
Sbjct: 261 TPKEPASTTPKEPT---PTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK 317
Query: 475 TPSQRAEREAARAGPEG--TSPPTPTPST----ATGGPPEDSPTVAPKSTTFLKNIRQFI 528
P+ +E A + T+P P P+T A P E +PT PK T
Sbjct: 318 EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPT-TPKEPT--------- 367
Query: 529 MPVVSARSSRVIKTPRRFMDEDP-PKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAP 587
P + K P ++P P PK P P +P P+EPAP + +P
Sbjct: 368 -PTTPKEPAPTTKEPAPTTPKEPAPTAPK---KPAPTTPKEPAPTTPKEPAPTTTKEPSP 423
Query: 588 TPPSTPVPLPEKRR-SILREPTFRWTSLTRELPPPPPAPPP----PPAPSPPPAPA-TSS 641
T P P P K + +EP + T+ P P P P PAP+ P PA T+
Sbjct: 424 TTPKEPAPTTTKSAPTTTKEPA---PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP 480
Query: 642 RRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPE-APEPEPPPADDSPAEPEPRAVGRTN 700
++P AP TP E P P E AP PA +P EP P T
Sbjct: 481 KKP----APT-TPKE-----------PAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 524
Query: 701 HLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQL 760
+ + P TTP K + PA P T +L T P+ P P+
Sbjct: 525 PTTPKKLTP--TTPEKLAPTTPEKPA----PTTPEELAPTTPEEPTPTTPEEPAPTTPKA 578
Query: 761 QPPPSPQQMPP 771
P +P++ P
Sbjct: 579 AAPNTPKEPAP 589
Score = 112 bits (279), Expect = 6e-24
Identities = 168/746 (22%), Positives = 240/746 (32%), Gaps = 168/746 (22%)
Query: 140 ALRSQRGRAPRGRGRKHKTTPLPP-PRLADVAPTPPKTPARKRGEEGTERMVQALTELLR 198
AL + + P TTP P P APT PK PA +
Sbjct: 250 ALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTK--------------- 294
Query: 199 RAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVP 258
AP P+ A P+T + P PA P K+ A ++A T PK P P P
Sbjct: 295 --SAPTTPKEPA--PTTTKEPAPTTPKEPA-PTTTKEPAPTTTKSAPTTPK--EPAPTTP 347
Query: 259 VKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGGLPFVIKFVSRAKKVKMGQ 318
K P P TP+ ++
Sbjct: 348 KK-------------PAPTTPKEPAPTT-------------------------------- 362
Query: 319 LSLGLESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQKLDDEEEEKKEEEEKDKEG 378
+E P+ + + +P K+ ++ +E
Sbjct: 363 -------------PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 409
Query: 379 EEKEERAVAEEMMPAAEKEEA-----------KLPPPPLTPPAPSPPPPLPPPSTSPPPP 427
++ +E P KE A K P P T AP+ P P +T P P
Sbjct: 410 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 469
Query: 428 LCPPPPPPVSP-PPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAAR 486
P P P +P P P+ P PA +E P T ++K P+ +E A
Sbjct: 470 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP-----TTTKK-------PAPTTPKEPAP 517
Query: 487 AGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRF 546
P+ T+P TP T T P + +PT K TP
Sbjct: 518 TTPKETAPTTPKKLTPT-TPEKLAPTTPEKPAP---------------------TTPEEL 555
Query: 547 MDEDPPKP-PKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILR 605
P +P P P P +P P+EPAP APT P P P K
Sbjct: 556 APTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKE----- 610
Query: 606 EPTFRWTSLTRELPPPPPAPP--PPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYE 663
T P AP PAP+ P PA P + P T + +
Sbjct: 611 ---------TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD------K 655
Query: 664 SVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHG 723
T P AP P+ PA +P EP P T +L AP TTP K
Sbjct: 656 PAPTTPKGTAPTTPK---EPAPTTPKEPAPTTPKGTAPTTLKEPAP--TTP-KKPAPKEL 709
Query: 724 APALSNGP-QTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGVGS 782
AP + GP T + P +T P P +P P+ + PP + + S
Sbjct: 710 APTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEV----S 765
Query: 783 LPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISDRGPV 842
P + E ++ K ++ + K + P PG + A K
Sbjct: 766 TPTTTKEPT--TIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATK---PEMTT 820
Query: 843 RSEDESVEAKRERPSGPESPVQGPRI 868
++D++ E R+ + PE+ P++
Sbjct: 821 TAKDKTTE--RDLRTTPETTTAAPKM 844
Score = 111 bits (277), Expect = 1e-23
Identities = 143/586 (24%), Positives = 205/586 (34%), Gaps = 77/586 (13%)
Query: 130 EDVAPSSLRSALRSQRGRAPRGRGRKHKTTPLPPPRLA-DVAPTPPKTPARKRGEEGTER 188
++ P++++SA + + AP T P P + APT PK PA +E
Sbjct: 271 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPT 330
Query: 189 MVQALTELLRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIP 248
++ + AP P+ A P+TP+ P P P K+ A E A T P
Sbjct: 331 TTKS-APTTPKEPAPTTPKKPA--PTTPKEPAPTTPKEPT-PTTPKEPAPTTKEPAPTTP 386
Query: 249 KPEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGGLPFVIKFV 308
K P P P K + K P P TP+ P K
Sbjct: 387 KE--PAPTAPKKPAPTTPK-----EPAPTTPKEPA------------------PTTTKEP 421
Query: 309 SRAKKVKMGQLSLGLESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQKLDDEEEEK 368
S + + +S + + +P K+ +E
Sbjct: 422 SPTTPKEPAPTTT------------KSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 469
Query: 369 KEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSP--PP 426
+E +K +E P KE A P P P P P T+P P
Sbjct: 470 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK 529
Query: 427 PLCPPPPPPVSP--PPLPSPPPP----PAQEEQEESPPPVVPATCSRKRGRP--PLTPSQ 478
L P P ++P P P+P P P E+ P PA + K P P P+
Sbjct: 530 KLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP 589
Query: 479 RAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTV--APKSTTFLKNIRQFIMPVVSARS 536
+E A P+ +P TP TA P +PT P TT K + + P +
Sbjct: 590 TTPKEPAPTTPKEPAPTTP-KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEP 648
Query: 537 SRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPL 596
+ D+ P PK + P +P P+EPAP APT P P
Sbjct: 649 TSTT------CDKPAPTTPKGTAPTTPKEP---APTTPKEPAPTTPKGTAPTTLKEPAPT 699
Query: 597 PEKR---RSILREPTFRWTSLTRELPPP------PPAPPPPPAPSPPPAPA-TSSRRPLL 646
K+ + + T TS T + P P P P PAP+ P PA T+ P
Sbjct: 700 TPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPP 759
Query: 647 LRAPQFTPSEAHLKIYESVLTPPPLGAPE-APEPEPPPADDSPAEP 691
+ TP+ K ++ P PE + EP P ++SP EP
Sbjct: 760 TTSEVSTPTTT--KEPTTIHKSPDESTPELSAEPTPKALENSPKEP 803
Score = 110 bits (274), Expect = 2e-23
Identities = 137/577 (23%), Positives = 188/577 (32%), Gaps = 56/577 (9%)
Query: 388 EEMMPAAEKEEAKLPPPPLTPP----APSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPS 443
+E P KE A P TP AP+ P P +T P P P + P P+
Sbjct: 255 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 314
Query: 444 PPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTAT 503
P PA +E P + + + P TP + A P T+P PTP+T
Sbjct: 315 TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP--TTPKEPTPTT-- 370
Query: 504 GGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVL 563
P E +PT + T K P +A TP+ E P PK
Sbjct: 371 --PKEPAPTTKEPAPTTPKE------PAPTAPKKPAPTTPK----EPAPTTPKEPAPTTT 418
Query: 564 RPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRR-SILREPTFRWTSLTRELPPPP 622
+ P SP P+EPAP + APT P P K + +EP+ T P
Sbjct: 419 KEP---SPTTPKEPAPT-TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 474
Query: 623 PAP--PPPPAPSPPPAPA-TSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEP 679
PAP P PAP+ P PA T+ + P AP T A E T P AP P+
Sbjct: 475 PAPTTPKKPAPTTPKEPAPTTPKEP----APTTTKKPAPTTPKEPAPTTPKETAPTTPKK 530
Query: 680 EPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQ 739
P + A P T L P TP P+ A
Sbjct: 531 LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTT--------------PEEPAPTTP 576
Query: 740 PLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGVGSLPLSGVEEKMFSLLKRA 799
A T P P +P P P P E A G+ P + E + K A
Sbjct: 577 KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA 636
Query: 800 KVQLFKIDQQQQQKVAAS--MPLSPGGQMEEVAGAVKQISDRGPVRSEDESVEAKRERPS 857
+L ++ P +P G + + P + + +
Sbjct: 637 PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEP 696
Query: 858 GPESPVQGPRIKHVCRHAAVALGQARAMVPEDVPRLSALPLRDRQDLATEDTSSASETES 917
P +P + P K + + P P ++ T A T
Sbjct: 697 APTTP-KKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPE 755
Query: 918 VPSRSRRGKVEAAGPGGESEPTGSGGTLAHTPRRSLP 954
P + E + P EPT T+ +P S P
Sbjct: 756 TPPPTTS---EVSTPTTTKEPT----TIHKSPDESTP 785
Score = 98.2 bits (243), Expect = 1e-19
Identities = 106/423 (25%), Positives = 152/423 (35%), Gaps = 59/423 (13%)
Query: 367 EKKEEEEKDKE-GEEKEERAVAEEMMPAAEKEEAK-LPPPPLTPPAPSPPPPLPPPSTSP 424
E KE +K+ + +E+ + + + EK AK L P P+P +
Sbjct: 192 ETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPAL 251
Query: 425 PPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREA 484
P P P P P P P + + P T ++ P P+ +E
Sbjct: 252 TTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP 311
Query: 485 ARAGPEGTSPPT---PTPSTATGGP--PEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRV 539
A P+ +P T P P+T P P++ PK P +
Sbjct: 312 APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK------------PAPTTPKEPA 359
Query: 540 IKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEK 599
TP+ E P PK E +P + P +P P+EPAP APT P P P K
Sbjct: 360 PTTPK----EPTPTTPK-EPAPTTKEP---APTTPKEPAPTAPKKPAPTTPKEPAPTTPK 411
Query: 600 RRSILREPTFRWTSLTRELPPPPPAPPPP------PAPSPPPAPATSSRRPLLLRAPQFT 653
EP + T+E P P P P P + PAP T+ P + P T
Sbjct: 412 ------EPA---PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPT 462
Query: 654 PSEAHLKIYESVLTPPPLGAPEAPEPEPP-----PADDSPAEPEPRAVGRTNHLSLPRFA 708
++ E T P AP P+ P PA +P EP P + + A
Sbjct: 463 TTK------EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 516
Query: 709 PVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQ 768
P TTP E +P L+ P T +L P+ L P P+ P +P++
Sbjct: 517 P--TTP--KETAPTTPKKLT--PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE 570
Query: 769 MPP 771
P
Sbjct: 571 PAP 573
Score = 74.7 bits (182), Expect = 1e-12
Identities = 111/488 (22%), Positives = 162/488 (33%), Gaps = 70/488 (14%)
Query: 157 KTTPLPPPRLADVAPTPPKTPARKRGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTP 216
K TP P +LA PT P+ PA EE + T AP P++ A P+TP
Sbjct: 530 KLTPTTPEKLA---PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA--PNTP 584
Query: 217 RRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGP 276
+ P PA ++ E A T PK P + KE P P
Sbjct: 585 KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTL------------KE---PAP 629
Query: 277 GTPRRGGQSSRGGRGGRGRGRGGGLPFVIKFVSRAKKVKMGQLSLGLESGQGQGQHEESW 336
TP++ P K + K + G +E
Sbjct: 630 TTPKKPAPKELA-------------PTTTKEPTSTTCDKPAPTT---PKGTAPTTPKEPA 673
Query: 337 QDVPQRRVGSG-QGGSPCWKKQEQKLDDEEEEKKEEEEKDKEG-----EEKEERAVAEEM 390
P+ + +G +P K+ ++ KE +G +K +E
Sbjct: 674 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 733
Query: 391 MPAAEKEEAKLPPPPLTPPAPSPPPP-LPPPSTSP-------PPPLCPPPPPPVSPPPLP 442
P KE P P TP P+P P PPP+TS P P S P L
Sbjct: 734 APTTPKE-----PAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELS 788
Query: 443 SPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQR---AEREAARAGPEGTSPPTPTP 499
+ P P A E + P VP T + +P +T + + ER+ T+ P T
Sbjct: 789 AEPTPKALENSPKEPG--VPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTK 846
Query: 500 STATGGPPEDSPTVAPKSTTFLKNIRQFIMPV------VSARSSRVIKTPRRFMDEDPPK 553
TAT + +T Q P + + +V T + +
Sbjct: 847 ETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMN 906
Query: 554 PPKVEVSPVLRPPIT-TSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWT 612
P+ P R + + P PQ+P P P + P T +P R+ + T
Sbjct: 907 KPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKT---MPRVRKPKTTPTPRKMT 963
Query: 613 SLTRELPP 620
S EL P
Sbjct: 964 STMPELNP 971
Score = 72.4 bits (176), Expect = 6e-12
Identities = 142/647 (21%), Positives = 198/647 (30%), Gaps = 87/647 (13%)
Query: 1797 AAEENQTIVHSPA----PSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSA 1852
+A+E Q+I + A P+S+ P +T P P P P S +
Sbjct: 213 SAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTT--PKEPASTTP 270
Query: 1853 PPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPA---- 1908
P P + A P P S P +P++ PT P
Sbjct: 271 KEPTPTTIKSA----PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKE 326
Query: 1909 PPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPP 1968
P + + +P P+ P P T+P + P PT+ T E AP P+P
Sbjct: 327 PAPTTTKSAPTTPKEPAPTTPKKPAPTTP--KEPAPTTPKEPTPTTPKEPAPTTKEPAPT 384
Query: 1969 PPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEES 2028
P++ P A EP ++ P ++ +E
Sbjct: 385 TPKEPAPTAPKKP-------------APTTPKEPAP----------TTPKEPAPTTTKEP 421
Query: 2029 SPTSRYIHFPVTVVSAPGL----APSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTP 2084
SPT+ P T SAP AP+ T AP + + ++P T
Sbjct: 422 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP--TT 479
Query: 2085 PSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGG--PGDGGAGPREESLPPAPPL 2142
P P A P P E K P + +E+ P P
Sbjct: 480 PKKP---------APTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKK 530
Query: 2143 ANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFV 2202
+ P + +P P T AP PE P P T K N
Sbjct: 531 LTPTTPEKLAPTTPEKPAPTTPE-ELAPTTPEEPTPTTPEEPAPTTPKAAAPN------- 582
Query: 2203 KMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTL 2262
E P P P P +PT P T P P G P + PAP P P
Sbjct: 583 -TPKEPAPTTPKEPAPTTPKEPAPTTPKE-TAPTTP-KGTAPTT-LKEPAPTTPKKPAPK 638
Query: 2263 VLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDED--------------GEASE 2308
L+ P K T + P P AP ++ E +
Sbjct: 639 ELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP 698
Query: 2309 DTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGE--PAGEESPGPLQERSPLLPLPEDGP 2366
TP+ P + + T T P E P + P P + P PE P
Sbjct: 699 TTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPP 758
Query: 2367 PQVPD-GPPDLLLESQWHHYSGEASSSE-EEPPSPDDKENQAPKRTG 2411
P + P E H S + S+ E P+P EN +PK G
Sbjct: 759 PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALEN-SPKEPG 804
Score = 68.6 bits (166), Expect = 8e-11
Identities = 124/588 (21%), Positives = 178/588 (30%), Gaps = 56/588 (9%)
Query: 1790 EEPAHLEAAEENQTIVHSPAPS---SEPPGGEDPPLDTDVLVPGAPERHSPIQNLDP--- 1843
+EP E T P P+ S P ++P T P P+ +P +P
Sbjct: 255 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 314
Query: 1844 -PLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPS-PGSPSSLTHHIPTV 1901
P P + PAP + A + + P P P+ P P+ T PT
Sbjct: 315 TPKEPAPTTTKEPAPTTTKSAP------TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTP 368
Query: 1902 GDPDFPAP------PRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTS 1955
P PAP P + P+P AP+ P P T+P + P PT+ T
Sbjct: 369 TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTP--KEPAPTTTKEPSPTTP 426
Query: 1956 GELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGS 2015
E AP +P ++ P + + T +
Sbjct: 427 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 486
Query: 2016 SHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAV 2075
+ P ++ +E +PT+ T AP P P+ T + E +
Sbjct: 487 TPKEPAPTTPKEPAPTT-------TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL 539
Query: 2076 QQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREES 2135
+ P+ P + A P P E P A
Sbjct: 540 APTTPEKPAPTTPEEL------APTTPEEPTPTTPEE---------PAPTTPKAAAPNTP 584
Query: 2136 LPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVN 2195
PAP P+ +P P T P L PAP PK K +
Sbjct: 585 KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK-EPAPTTPKKPAPKELAPT 643
Query: 2196 KLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLL--GVLPVVGVVRPAP 2253
+ + P P P P +PT P P P G P + PAP
Sbjct: 644 TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKE----PAPTTPKGTAPTT-LKEPAP 698
Query: 2254 PPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQV 2313
P P L+ P K T + P P AP + + + TP+
Sbjct: 699 TTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPK--KPAPTTPET 756
Query: 2314 PGLGSGGFSR-VRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLP 2360
P + S K PT + E + E +P L E SP P
Sbjct: 757 PPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKAL-ENSPKEP 803
Score = 67.0 bits (162), Expect = 2e-10
Identities = 112/481 (23%), Positives = 162/481 (33%), Gaps = 55/481 (11%)
Query: 1790 EEPAHLEAAEENQTIVHSPAPSSEPPGGEDP----PLDTDVLVPGAPERHSPIQNLDPP- 1844
+EPA E T PAP+++ P P P P P+ +P +P
Sbjct: 356 KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP 415
Query: 1845 ---LRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTV 1901
P + PAP + A P + P S P SP++ PT
Sbjct: 416 TTTKEPSPTTPKEPAPTTTKSA----PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT 471
Query: 1902 GDPDFPAP-------PRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVP--PPTSVVTA-- 1950
P PAP P + P+P P+ P P T+P+ P P + T
Sbjct: 472 --PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK 529
Query: 1951 -LTPTSGE-LAPPGP-APSPPPPEDLGPDF-EDMEVVSGLSAADLDFAASLLGTEPFQEE 2006
LTPT+ E LAP P P+P PE+L P E+ + A A+ T
Sbjct: 530 KLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP 589
Query: 2007 IVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQL--DGV 2064
++ P ++ +E++PT+ P T+ AP+ TP P ++L
Sbjct: 590 TTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP---APT-TPKKPAPKELAPTTT 645
Query: 2065 DDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGP 2124
+ T + + +GT P+ P A P P LK
Sbjct: 646 KEPTSTTCDKPAPTTPKGTAPTTPKE------PAPTTPKEPAPTTPKGTAPTTLKEPAPT 699
Query: 2125 GDGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLP--GAPGVRVLSLGPAPE 2182
P+E AP G + +P P T P AP PE
Sbjct: 700 TPKKPAPKE----LAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPE 755
Query: 2183 PPKPATSKII--LVNKLGQVFVKMAGE------GEPVPPPVKQPPLPPTISPTAPTSWTL 2234
P P TS++ K K E EP P ++ P P + T + T
Sbjct: 756 TPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATK 815
Query: 2235 P 2235
P
Sbjct: 816 P 816
Score = 57.8 bits (138), Expect = 1e-07
Identities = 105/513 (20%), Positives = 165/513 (32%), Gaps = 81/513 (15%)
Query: 1918 PLAPRP--PPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGP 1975
P+ PRP PP+ S L V T+V T T T+ + + ++
Sbjct: 164 PINPRPSLPPNSDTSK----ETSLTVNKETTVETKETTTTNK-------QTSTDGKEKTT 212
Query: 1976 DFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYI 2035
++ + + SA DL + +L + E G ++ P ++ +E + T+
Sbjct: 213 SAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKE 272
Query: 2036 HFPVTVVSAPGL----APSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVV 2091
P T+ SAP AP+ T AP + + ++P T P
Sbjct: 273 PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT 332
Query: 2092 RAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQG 2151
++ P E P+ P++ + P P + P +
Sbjct: 333 KSA-------PTTPKEPAPTT------------------PKKPA-PTTPKEPAPTTPKEP 366
Query: 2152 LTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPV 2211
+P +P T AP AP+ P P T K EP
Sbjct: 367 TPTTPKEPAPTTK--EPAPTTPKEPAPTAPKKPAPTTPK------------------EPA 406
Query: 2212 PPPVKQP-------PLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVL 2264
P K+P P P T APT+ P P P P P P T
Sbjct: 407 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP-TTTK 465
Query: 2265 SSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRV 2324
P +P A + + PAP K P + + TP+ P +
Sbjct: 466 EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP-----TTP 520
Query: 2325 RMKTPTVRGVLDLDRPGE--PAGEESPGPLQERSPLLPLPEDGPPQVPDGPPDLLLESQW 2382
+ PT L P + P E P P PE+ P P+ P ++
Sbjct: 521 KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA 580
Query: 2383 HHYSGEASSSEEEPPSPDDKENQA---PKRTGP 2412
+ E + + + P+P + A PK T P
Sbjct: 581 PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 613
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 112 bits (279), Expect = 6e-24
Identities = 114/431 (26%), Positives = 161/431 (37%), Gaps = 58/431 (13%)
Query: 357 QEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMM--PAAEKEEAKLPPPPLTPPAPSPP 414
++ D +E+ +E + E ++ A +++ P + E P TP P+P
Sbjct: 253 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPT 312
Query: 415 PPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPL 474
P P ST+P P P S P P P P + +P P T P
Sbjct: 313 TPKEPASTTPKEPT---PTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK 369
Query: 475 TPSQRAEREAARAGPEG--TSPPTPTPST----ATGGPPEDSPTVAPKSTTFLKNIRQFI 528
P+ +E A + T+P P P+T A P E +PT PK T
Sbjct: 370 EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPT-TPKEPT--------- 419
Query: 529 MPVVSARSSRVIKTPRRFMDEDP-PKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAP 587
P + K P ++P P PK P P +P P+EPAP + +P
Sbjct: 420 -PTTPKEPAPTTKEPAPTTPKEPAPTAPK---KPAPTTPKEPAPTTPKEPAPTTTKEPSP 475
Query: 588 TPPSTPVPLPEKRR-SILREPTFRWTSLTRELPPPPPAPPP----PPAPSPPPAPA-TSS 641
T P P P K + +EP + T+ P P P P PAP+ P PA T+
Sbjct: 476 TTPKEPAPTTTKSAPTTTKEPA---PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP 532
Query: 642 RRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPE-APEPEPPPADDSPAEPEPRAVGRTN 700
++P AP TP E P P E AP PA +P EP P T
Sbjct: 533 KKP----APT-TPKE-----------PAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 576
Query: 701 HLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQL 760
+ + P TTP K + PA P T +L T P+ P P+
Sbjct: 577 PTTPKKLTP--TTPEKLAPTTPEKPA----PTTPEELAPTTPEEPTPTTPEEPAPTTPKA 630
Query: 761 QPPPSPQQMPP 771
P +P++ P
Sbjct: 631 AAPNTPKEPAP 641
Score = 112 bits (279), Expect = 6e-24
Identities = 168/746 (22%), Positives = 240/746 (32%), Gaps = 168/746 (22%)
Query: 140 ALRSQRGRAPRGRGRKHKTTPLPP-PRLADVAPTPPKTPARKRGEEGTERMVQALTELLR 198
AL + + P TTP P P APT PK PA +
Sbjct: 302 ALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTK--------------- 346
Query: 199 RAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVP 258
AP P+ A P+T + P PA P K+ A ++A T PK P P P
Sbjct: 347 --SAPTTPKEPA--PTTTKEPAPTTPKEPA-PTTTKEPAPTTTKSAPTTPK--EPAPTTP 399
Query: 259 VKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGGLPFVIKFVSRAKKVKMGQ 318
K P P TP+ ++
Sbjct: 400 KK-------------PAPTTPKEPAPTT-------------------------------- 414
Query: 319 LSLGLESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQKLDDEEEEKKEEEEKDKEG 378
+E P+ + + +P K+ ++ +E
Sbjct: 415 -------------PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 461
Query: 379 EEKEERAVAEEMMPAAEKEEA-----------KLPPPPLTPPAPSPPPPLPPPSTSPPPP 427
++ +E P KE A K P P T AP+ P P +T P P
Sbjct: 462 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 521
Query: 428 LCPPPPPPVSP-PPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAAR 486
P P P +P P P+ P PA +E P T ++K P+ +E A
Sbjct: 522 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP-----TTTKK-------PAPTTPKEPAP 569
Query: 487 AGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRF 546
P+ T+P TP T T P + +PT K TP
Sbjct: 570 TTPKETAPTTPKKLTPT-TPEKLAPTTPEKPAP---------------------TTPEEL 607
Query: 547 MDEDPPKP-PKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILR 605
P +P P P P +P P+EPAP APT P P P K
Sbjct: 608 APTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKE----- 662
Query: 606 EPTFRWTSLTRELPPPPPAPP--PPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYE 663
T P AP PAP+ P PA P + P T + +
Sbjct: 663 ---------TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD------K 707
Query: 664 SVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHG 723
T P AP P+ PA +P EP P T +L AP TTP K
Sbjct: 708 PAPTTPKGTAPTTPK---EPAPTTPKEPAPTTPKGTAPTTLKEPAP--TTP-KKPAPKEL 761
Query: 724 APALSNGP-QTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGVGS 782
AP + GP T + P +T P P +P P+ + PP + + S
Sbjct: 762 APTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEV----S 817
Query: 783 LPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISDRGPV 842
P + E ++ K ++ + K + P PG + A K
Sbjct: 818 TPTTTKEPT--TIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATK---PEMTT 872
Query: 843 RSEDESVEAKRERPSGPESPVQGPRI 868
++D++ E R+ + PE+ P++
Sbjct: 873 TAKDKTTE--RDLRTTPETTTAAPKM 896
Score = 111 bits (277), Expect = 1e-23
Identities = 143/586 (24%), Positives = 205/586 (34%), Gaps = 77/586 (13%)
Query: 130 EDVAPSSLRSALRSQRGRAPRGRGRKHKTTPLPPPRLA-DVAPTPPKTPARKRGEEGTER 188
++ P++++SA + + AP T P P + APT PK PA +E
Sbjct: 323 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPT 382
Query: 189 MVQALTELLRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIP 248
++ + AP P+ A P+TP+ P P P K+ A E A T P
Sbjct: 383 TTKS-APTTPKEPAPTTPKKPA--PTTPKEPAPTTPKEPT-PTTPKEPAPTTKEPAPTTP 438
Query: 249 KPEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGGLPFVIKFV 308
K P P P K + K P P TP+ P K
Sbjct: 439 KE--PAPTAPKKPAPTTPK-----EPAPTTPKEPA------------------PTTTKEP 473
Query: 309 SRAKKVKMGQLSLGLESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQKLDDEEEEK 368
S + + +S + + +P K+ +E
Sbjct: 474 SPTTPKEPAPTTT------------KSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 521
Query: 369 KEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSP--PP 426
+E +K +E P KE A P P P P P T+P P
Sbjct: 522 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK 581
Query: 427 PLCPPPPPPVSP--PPLPSPPPP----PAQEEQEESPPPVVPATCSRKRGRP--PLTPSQ 478
L P P ++P P P+P P P E+ P PA + K P P P+
Sbjct: 582 KLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP 641
Query: 479 RAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTV--APKSTTFLKNIRQFIMPVVSARS 536
+E A P+ +P TP TA P +PT P TT K + + P +
Sbjct: 642 TTPKEPAPTTPKEPAPTTP-KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEP 700
Query: 537 SRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPL 596
+ D+ P PK + P +P P+EPAP APT P P
Sbjct: 701 TSTT------CDKPAPTTPKGTAPTTPKEP---APTTPKEPAPTTPKGTAPTTLKEPAPT 751
Query: 597 PEKR---RSILREPTFRWTSLTRELPPP------PPAPPPPPAPSPPPAPA-TSSRRPLL 646
K+ + + T TS T + P P P P PAP+ P PA T+ P
Sbjct: 752 TPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPP 811
Query: 647 LRAPQFTPSEAHLKIYESVLTPPPLGAPE-APEPEPPPADDSPAEP 691
+ TP+ K ++ P PE + EP P ++SP EP
Sbjct: 812 TTSEVSTPTTT--KEPTTIHKSPDESTPELSAEPTPKALENSPKEP 855
Score = 110 bits (274), Expect = 2e-23
Identities = 137/577 (23%), Positives = 188/577 (32%), Gaps = 56/577 (9%)
Query: 388 EEMMPAAEKEEAKLPPPPLTPP----APSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPS 443
+E P KE A P TP AP+ P P +T P P P + P P+
Sbjct: 307 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 366
Query: 444 PPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTAT 503
P PA +E P + + + P TP + A P T+P PTP+T
Sbjct: 367 TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP--TTPKEPTPTT-- 422
Query: 504 GGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVL 563
P E +PT + T K P +A TP+ E P PK
Sbjct: 423 --PKEPAPTTKEPAPTTPKE------PAPTAPKKPAPTTPK----EPAPTTPKEPAPTTT 470
Query: 564 RPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRR-SILREPTFRWTSLTRELPPPP 622
+ P SP P+EPAP + APT P P K + +EP+ T P
Sbjct: 471 KEP---SPTTPKEPAPT-TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 526
Query: 623 PAP--PPPPAPSPPPAPA-TSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEP 679
PAP P PAP+ P PA T+ + P AP T A E T P AP P+
Sbjct: 527 PAPTTPKKPAPTTPKEPAPTTPKEP----APTTTKKPAPTTPKEPAPTTPKETAPTTPKK 582
Query: 680 EPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQ 739
P + A P T L P TP P+ A
Sbjct: 583 LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTT--------------PEEPAPTTP 628
Query: 740 PLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGVGSLPLSGVEEKMFSLLKRA 799
A T P P +P P P P E A G+ P + E + K A
Sbjct: 629 KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA 688
Query: 800 KVQLFKIDQQQQQKVAAS--MPLSPGGQMEEVAGAVKQISDRGPVRSEDESVEAKRERPS 857
+L ++ P +P G + + P + + +
Sbjct: 689 PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEP 748
Query: 858 GPESPVQGPRIKHVCRHAAVALGQARAMVPEDVPRLSALPLRDRQDLATEDTSSASETES 917
P +P + P K + + P P ++ T A T
Sbjct: 749 APTTP-KKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPE 807
Query: 918 VPSRSRRGKVEAAGPGGESEPTGSGGTLAHTPRRSLP 954
P + E + P EPT T+ +P S P
Sbjct: 808 TPPPTTS---EVSTPTTTKEPT----TIHKSPDESTP 837
Score = 98.2 bits (243), Expect = 1e-19
Identities = 106/423 (25%), Positives = 152/423 (35%), Gaps = 59/423 (13%)
Query: 367 EKKEEEEKDKE-GEEKEERAVAEEMMPAAEKEEAK-LPPPPLTPPAPSPPPPLPPPSTSP 424
E KE +K+ + +E+ + + + EK AK L P P+P +
Sbjct: 244 ETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPAL 303
Query: 425 PPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREA 484
P P P P P P P + + P T ++ P P+ +E
Sbjct: 304 TTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP 363
Query: 485 ARAGPEGTSPPT---PTPSTATGGP--PEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRV 539
A P+ +P T P P+T P P++ PK P +
Sbjct: 364 APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK------------PAPTTPKEPA 411
Query: 540 IKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEK 599
TP+ E P PK E +P + P +P P+EPAP APT P P P K
Sbjct: 412 PTTPK----EPTPTTPK-EPAPTTKEP---APTTPKEPAPTAPKKPAPTTPKEPAPTTPK 463
Query: 600 RRSILREPTFRWTSLTRELPPPPPAPPPP------PAPSPPPAPATSSRRPLLLRAPQFT 653
EP + T+E P P P P P + PAP T+ P + P T
Sbjct: 464 ------EPA---PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPT 514
Query: 654 PSEAHLKIYESVLTPPPLGAPEAPEPEPP-----PADDSPAEPEPRAVGRTNHLSLPRFA 708
++ E T P AP P+ P PA +P EP P + + A
Sbjct: 515 TTK------EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 568
Query: 709 PVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQ 768
P TTP E +P L+ P T +L P+ L P P+ P +P++
Sbjct: 569 P--TTP--KETAPTTPKKLT--PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE 622
Query: 769 MPP 771
P
Sbjct: 623 PAP 625
Score = 74.7 bits (182), Expect = 1e-12
Identities = 111/488 (22%), Positives = 162/488 (33%), Gaps = 70/488 (14%)
Query: 157 KTTPLPPPRLADVAPTPPKTPARKRGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTP 216
K TP P +LA PT P+ PA EE + T AP P++ A P+TP
Sbjct: 582 KLTPTTPEKLA---PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA--PNTP 636
Query: 217 RRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGP 276
+ P PA ++ E A T PK P + KE P P
Sbjct: 637 KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTL------------KE---PAP 681
Query: 277 GTPRRGGQSSRGGRGGRGRGRGGGLPFVIKFVSRAKKVKMGQLSLGLESGQGQGQHEESW 336
TP++ P K + K + G +E
Sbjct: 682 TTPKKPAPKELA-------------PTTTKEPTSTTCDKPAPTT---PKGTAPTTPKEPA 725
Query: 337 QDVPQRRVGSG-QGGSPCWKKQEQKLDDEEEEKKEEEEKDKEG-----EEKEERAVAEEM 390
P+ + +G +P K+ ++ KE +G +K +E
Sbjct: 726 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 785
Query: 391 MPAAEKEEAKLPPPPLTPPAPSPPPP-LPPPSTSP-------PPPLCPPPPPPVSPPPLP 442
P KE P P TP P+P P PPP+TS P P S P L
Sbjct: 786 APTTPKE-----PAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELS 840
Query: 443 SPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQR---AEREAARAGPEGTSPPTPTP 499
+ P P A E + P VP T + +P +T + + ER+ T+ P T
Sbjct: 841 AEPTPKALENSPKEPG--VPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTK 898
Query: 500 STATGGPPEDSPTVAPKSTTFLKNIRQFIMPV------VSARSSRVIKTPRRFMDEDPPK 553
TAT + +T Q P + + +V T + +
Sbjct: 899 ETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMN 958
Query: 554 PPKVEVSPVLRPPIT-TSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWT 612
P+ P R + + P PQ+P P P + P T +P R+ + T
Sbjct: 959 KPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKT---MPRVRKPKTTPTPRKMT 1015
Query: 613 SLTRELPP 620
S EL P
Sbjct: 1016 STMPELNP 1023
Score = 72.4 bits (176), Expect = 6e-12
Identities = 142/647 (21%), Positives = 198/647 (30%), Gaps = 87/647 (13%)
Query: 1797 AAEENQTIVHSPA----PSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSA 1852
+A+E Q+I + A P+S+ P +T P P P P S +
Sbjct: 265 SAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTT--PKEPASTTP 322
Query: 1853 PPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPA---- 1908
P P + A P P S P +P++ PT P
Sbjct: 323 KEPTPTTIKSA----PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKE 378
Query: 1909 PPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPP 1968
P + + +P P+ P P T+P + P PT+ T E AP P+P
Sbjct: 379 PAPTTTKSAPTTPKEPAPTTPKKPAPTTP--KEPAPTTPKEPTPTTPKEPAPTTKEPAPT 436
Query: 1969 PPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEES 2028
P++ P A EP ++ P ++ +E
Sbjct: 437 TPKEPAPTAPKKP-------------APTTPKEPAP----------TTPKEPAPTTTKEP 473
Query: 2029 SPTSRYIHFPVTVVSAPGL----APSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTP 2084
SPT+ P T SAP AP+ T AP + + ++P T
Sbjct: 474 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP--TT 531
Query: 2085 PSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGG--PGDGGAGPREESLPPAPPL 2142
P P A P P E K P + +E+ P P
Sbjct: 532 PKKP---------APTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKK 582
Query: 2143 ANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFV 2202
+ P + +P P T AP PE P P T K N
Sbjct: 583 LTPTTPEKLAPTTPEKPAPTTPE-ELAPTTPEEPTPTTPEEPAPTTPKAAAPN------- 634
Query: 2203 KMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTL 2262
E P P P P +PT P T P P G P + PAP P P
Sbjct: 635 -TPKEPAPTTPKEPAPTTPKEPAPTTPKE-TAPTTP-KGTAPTT-LKEPAPTTPKKPAPK 690
Query: 2263 VLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDED--------------GEASE 2308
L+ P K T + P P AP ++ E +
Sbjct: 691 ELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP 750
Query: 2309 DTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGE--PAGEESPGPLQERSPLLPLPEDGP 2366
TP+ P + + T T P E P + P P + P PE P
Sbjct: 751 TTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPP 810
Query: 2367 PQVPD-GPPDLLLESQWHHYSGEASSSE-EEPPSPDDKENQAPKRTG 2411
P + P E H S + S+ E P+P EN +PK G
Sbjct: 811 PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALEN-SPKEPG 856
Score = 68.6 bits (166), Expect = 8e-11
Identities = 124/588 (21%), Positives = 178/588 (30%), Gaps = 56/588 (9%)
Query: 1790 EEPAHLEAAEENQTIVHSPAPS---SEPPGGEDPPLDTDVLVPGAPERHSPIQNLDP--- 1843
+EP E T P P+ S P ++P T P P+ +P +P
Sbjct: 307 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 366
Query: 1844 -PLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPS-PGSPSSLTHHIPTV 1901
P P + PAP + A + + P P P+ P P+ T PT
Sbjct: 367 TPKEPAPTTTKEPAPTTTKSAP------TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTP 420
Query: 1902 GDPDFPAP------PRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTS 1955
P PAP P + P+P AP+ P P T+P + P PT+ T
Sbjct: 421 TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTP--KEPAPTTTKEPSPTTP 478
Query: 1956 GELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGS 2015
E AP +P ++ P + + T +
Sbjct: 479 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 538
Query: 2016 SHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAV 2075
+ P ++ +E +PT+ T AP P P+ T + E +
Sbjct: 539 TPKEPAPTTPKEPAPTT-------TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL 591
Query: 2076 QQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREES 2135
+ P+ P + A P P E P A
Sbjct: 592 APTTPEKPAPTTPEEL------APTTPEEPTPTTPEE---------PAPTTPKAAAPNTP 636
Query: 2136 LPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVN 2195
PAP P+ +P P T P L PAP PK K +
Sbjct: 637 KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK-EPAPTTPKKPAPKELAPT 695
Query: 2196 KLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLL--GVLPVVGVVRPAP 2253
+ + P P P P +PT P P P G P + PAP
Sbjct: 696 TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKE----PAPTTPKGTAPTT-LKEPAP 750
Query: 2254 PPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQV 2313
P P L+ P K T + P P AP + + + TP+
Sbjct: 751 TTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPK--KPAPTTPET 808
Query: 2314 PGLGSGGFSR-VRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLP 2360
P + S K PT + E + E +P L E SP P
Sbjct: 809 PPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKAL-ENSPKEP 855
Score = 67.0 bits (162), Expect = 2e-10
Identities = 112/481 (23%), Positives = 162/481 (33%), Gaps = 55/481 (11%)
Query: 1790 EEPAHLEAAEENQTIVHSPAPSSEPPGGEDP----PLDTDVLVPGAPERHSPIQNLDPP- 1844
+EPA E T PAP+++ P P P P P+ +P +P
Sbjct: 408 KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP 467
Query: 1845 ---LRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTV 1901
P + PAP + A P + P S P SP++ PT
Sbjct: 468 TTTKEPSPTTPKEPAPTTTKSA----PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT 523
Query: 1902 GDPDFPAP-------PRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVP--PPTSVVTA-- 1950
P PAP P + P+P P+ P P T+P+ P P + T
Sbjct: 524 --PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK 581
Query: 1951 -LTPTSGE-LAPPGP-APSPPPPEDLGPDF-EDMEVVSGLSAADLDFAASLLGTEPFQEE 2006
LTPT+ E LAP P P+P PE+L P E+ + A A+ T
Sbjct: 582 KLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP 641
Query: 2007 IVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQL--DGV 2064
++ P ++ +E++PT+ P T+ AP+ TP P ++L
Sbjct: 642 TTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP---APT-TPKKPAPKELAPTTT 697
Query: 2065 DDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGP 2124
+ T + + +GT P+ P A P P LK
Sbjct: 698 KEPTSTTCDKPAPTTPKGTAPTTPKE------PAPTTPKEPAPTTPKGTAPTTLKEPAPT 751
Query: 2125 GDGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLP--GAPGVRVLSLGPAPE 2182
P+E AP G + +P P T P AP PE
Sbjct: 752 TPKKPAPKE----LAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPE 807
Query: 2183 PPKPATSKII--LVNKLGQVFVKMAGE------GEPVPPPVKQPPLPPTISPTAPTSWTL 2234
P P TS++ K K E EP P ++ P P + T + T
Sbjct: 808 TPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATK 867
Query: 2235 P 2235
P
Sbjct: 868 P 868
Score = 60.1 bits (144), Expect = 3e-08
Identities = 122/607 (20%), Positives = 179/607 (29%), Gaps = 116/607 (19%)
Query: 370 EEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPST------- 422
E E+ +E + + ++ P E A++ P P + PPP T
Sbjct: 35 ESFERGRECDCDAQCKKYDKCCPDYESFCAEVHNPTSPPSSKKAPPPSGASQTIKSTTKR 94
Query: 423 SPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRK-------------- 468
SP PP + + +E S ++ RK
Sbjct: 95 SPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQ 154
Query: 469 -----------RGRPPLTPSQRAEREAARAGPEG----TSPPTPT---------PSTATG 504
R + TP EA G T+P T T P T
Sbjct: 155 KKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTA 214
Query: 505 GPPEDSPTVAPKS----------------------TTFLKNIRQFIMPVVSAR------- 535
P P++ P S TT + SA+
Sbjct: 215 KPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEK 274
Query: 536 -SSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTP----- 589
S++ + + + + PK P L P +P P+EPA + P+ PTP
Sbjct: 275 TSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPA--STTPKEPTPTTIKS 332
Query: 590 -PSTP-VPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPP------------------- 628
P+TP P P +S P + T+E P P P P
Sbjct: 333 APTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPK 392
Query: 629 -PAPSPPPAPATSSRRPLLLRAPQ----FTPSEAHLKIYESVLTPPPLGAPEAPEPEPP- 682
PAP+ P PA ++ + P+ TP E E T P AP AP+ P
Sbjct: 393 EPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT 452
Query: 683 ----PADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKA---EVSPHGAPALSNGPQTQA 735
PA +P EP P + + AP T E +P + P+ +
Sbjct: 453 TPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPS 512
Query: 736 QLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGVGSLPLSGVEEKMFSL 795
A T P P +P P P P E A P + E +
Sbjct: 513 PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP 572
Query: 796 LKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISDRGPVRSEDESVEAKRER 855
+ A K+ +K+A + P P E E K
Sbjct: 573 KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA 632
Query: 856 PSGPESP 862
P+ P+ P
Sbjct: 633 PNTPKEP 639
Score = 57.8 bits (138), Expect = 1e-07
Identities = 105/513 (20%), Positives = 165/513 (32%), Gaps = 81/513 (15%)
Query: 1918 PLAPRP--PPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGP 1975
P+ PRP PP+ S L V T+V T T T+ + + ++
Sbjct: 216 PINPRPSLPPNSDTSK----ETSLTVNKETTVETKETTTTNK-------QTSTDGKEKTT 264
Query: 1976 DFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYI 2035
++ + + SA DL + +L + E G ++ P ++ +E + T+
Sbjct: 265 SAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKE 324
Query: 2036 HFPVTVVSAPGL----APSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVV 2091
P T+ SAP AP+ T AP + + ++P T P
Sbjct: 325 PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT 384
Query: 2092 RAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQG 2151
++ P E P+ P++ + P P + P +
Sbjct: 385 KSA-------PTTPKEPAPTT------------------PKKPA-PTTPKEPAPTTPKEP 418
Query: 2152 LTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPV 2211
+P +P T AP AP+ P P T K EP
Sbjct: 419 TPTTPKEPAPTTK--EPAPTTPKEPAPTAPKKPAPTTPK------------------EPA 458
Query: 2212 PPPVKQP-------PLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVL 2264
P K+P P P T APT+ P P P P P P T
Sbjct: 459 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP-TTTK 517
Query: 2265 SSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRV 2324
P +P A + + PAP K P + + TP+ P +
Sbjct: 518 EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP-----TTP 572
Query: 2325 RMKTPTVRGVLDLDRPGE--PAGEESPGPLQERSPLLPLPEDGPPQVPDGPPDLLLESQW 2382
+ PT L P + P E P P PE+ P P+ P ++
Sbjct: 573 KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA 632
Query: 2383 HHYSGEASSSEEEPPSPDDKENQA---PKRTGP 2412
+ E + + + P+P + A PK T P
Sbjct: 633 PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 665
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 112 bits (279), Expect = 6e-24
Identities = 114/431 (26%), Positives = 161/431 (37%), Gaps = 58/431 (13%)
Query: 357 QEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMM--PAAEKEEAKLPPPPLTPPAPSPP 414
++ D +E+ +E + E ++ A +++ P + E P TP P+P
Sbjct: 294 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPT 353
Query: 415 PPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPL 474
P P ST+P P P S P P P P + +P P T P
Sbjct: 354 TPKEPASTTPKEPT---PTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK 410
Query: 475 TPSQRAEREAARAGPEG--TSPPTPTPST----ATGGPPEDSPTVAPKSTTFLKNIRQFI 528
P+ +E A + T+P P P+T A P E +PT PK T
Sbjct: 411 EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPT-TPKEPT--------- 460
Query: 529 MPVVSARSSRVIKTPRRFMDEDP-PKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAP 587
P + K P ++P P PK P P +P P+EPAP + +P
Sbjct: 461 -PTTPKEPAPTTKEPAPTTPKEPAPTAPK---KPAPTTPKEPAPTTPKEPAPTTTKEPSP 516
Query: 588 TPPSTPVPLPEKRR-SILREPTFRWTSLTRELPPPPPAPPP----PPAPSPPPAPA-TSS 641
T P P P K + +EP + T+ P P P P PAP+ P PA T+
Sbjct: 517 TTPKEPAPTTTKSAPTTTKEPA---PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP 573
Query: 642 RRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPE-APEPEPPPADDSPAEPEPRAVGRTN 700
++P AP TP E P P E AP PA +P EP P T
Sbjct: 574 KKP----APT-TPKE-----------PAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 617
Query: 701 HLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQL 760
+ + P TTP K + PA P T +L T P+ P P+
Sbjct: 618 PTTPKKLTP--TTPEKLAPTTPEKPA----PTTPEELAPTTPEEPTPTTPEEPAPTTPKA 671
Query: 761 QPPPSPQQMPP 771
P +P++ P
Sbjct: 672 AAPNTPKEPAP 682
Score = 112 bits (279), Expect = 6e-24
Identities = 168/746 (22%), Positives = 240/746 (32%), Gaps = 168/746 (22%)
Query: 140 ALRSQRGRAPRGRGRKHKTTPLPP-PRLADVAPTPPKTPARKRGEEGTERMVQALTELLR 198
AL + + P TTP P P APT PK PA +
Sbjct: 343 ALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTK--------------- 387
Query: 199 RAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVP 258
AP P+ A P+T + P PA P K+ A ++A T PK P P P
Sbjct: 388 --SAPTTPKEPA--PTTTKEPAPTTPKEPA-PTTTKEPAPTTTKSAPTTPK--EPAPTTP 440
Query: 259 VKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGGLPFVIKFVSRAKKVKMGQ 318
K P P TP+ ++
Sbjct: 441 KK-------------PAPTTPKEPAPTT-------------------------------- 455
Query: 319 LSLGLESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQKLDDEEEEKKEEEEKDKEG 378
+E P+ + + +P K+ ++ +E
Sbjct: 456 -------------PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 502
Query: 379 EEKEERAVAEEMMPAAEKEEA-----------KLPPPPLTPPAPSPPPPLPPPSTSPPPP 427
++ +E P KE A K P P T AP+ P P +T P P
Sbjct: 503 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 562
Query: 428 LCPPPPPPVSP-PPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAAR 486
P P P +P P P+ P PA +E P T ++K P+ +E A
Sbjct: 563 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP-----TTTKK-------PAPTTPKEPAP 610
Query: 487 AGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRF 546
P+ T+P TP T T P + +PT K TP
Sbjct: 611 TTPKETAPTTPKKLTPT-TPEKLAPTTPEKPAP---------------------TTPEEL 648
Query: 547 MDEDPPKP-PKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILR 605
P +P P P P +P P+EPAP APT P P P K
Sbjct: 649 APTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKE----- 703
Query: 606 EPTFRWTSLTRELPPPPPAPP--PPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYE 663
T P AP PAP+ P PA P + P T + +
Sbjct: 704 ---------TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD------K 748
Query: 664 SVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHG 723
T P AP P+ PA +P EP P T +L AP TTP K
Sbjct: 749 PAPTTPKGTAPTTPK---EPAPTTPKEPAPTTPKGTAPTTLKEPAP--TTP-KKPAPKEL 802
Query: 724 APALSNGP-QTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGVGS 782
AP + GP T + P +T P P +P P+ + PP + + S
Sbjct: 803 APTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEV----S 858
Query: 783 LPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISDRGPV 842
P + E ++ K ++ + K + P PG + A K
Sbjct: 859 TPTTTKEPT--TIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATK---PEMTT 913
Query: 843 RSEDESVEAKRERPSGPESPVQGPRI 868
++D++ E R+ + PE+ P++
Sbjct: 914 TAKDKTTE--RDLRTTPETTTAAPKM 937
Score = 111 bits (277), Expect = 1e-23
Identities = 143/586 (24%), Positives = 205/586 (34%), Gaps = 77/586 (13%)
Query: 130 EDVAPSSLRSALRSQRGRAPRGRGRKHKTTPLPPPRLA-DVAPTPPKTPARKRGEEGTER 188
++ P++++SA + + AP T P P + APT PK PA +E
Sbjct: 364 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPT 423
Query: 189 MVQALTELLRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIP 248
++ + AP P+ A P+TP+ P P P K+ A E A T P
Sbjct: 424 TTKS-APTTPKEPAPTTPKKPA--PTTPKEPAPTTPKEPT-PTTPKEPAPTTKEPAPTTP 479
Query: 249 KPEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGGLPFVIKFV 308
K P P P K + K P P TP+ P K
Sbjct: 480 KE--PAPTAPKKPAPTTPK-----EPAPTTPKEPA------------------PTTTKEP 514
Query: 309 SRAKKVKMGQLSLGLESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQKLDDEEEEK 368
S + + +S + + +P K+ +E
Sbjct: 515 SPTTPKEPAPTTT------------KSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 562
Query: 369 KEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSP--PP 426
+E +K +E P KE A P P P P P T+P P
Sbjct: 563 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK 622
Query: 427 PLCPPPPPPVSP--PPLPSPPPP----PAQEEQEESPPPVVPATCSRKRGRP--PLTPSQ 478
L P P ++P P P+P P P E+ P PA + K P P P+
Sbjct: 623 KLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP 682
Query: 479 RAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTV--APKSTTFLKNIRQFIMPVVSARS 536
+E A P+ +P TP TA P +PT P TT K + + P +
Sbjct: 683 TTPKEPAPTTPKEPAPTTP-KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEP 741
Query: 537 SRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPL 596
+ D+ P PK + P +P P+EPAP APT P P
Sbjct: 742 TSTT------CDKPAPTTPKGTAPTTPKEP---APTTPKEPAPTTPKGTAPTTLKEPAPT 792
Query: 597 PEKR---RSILREPTFRWTSLTRELPPP------PPAPPPPPAPSPPPAPA-TSSRRPLL 646
K+ + + T TS T + P P P P PAP+ P PA T+ P
Sbjct: 793 TPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPP 852
Query: 647 LRAPQFTPSEAHLKIYESVLTPPPLGAPE-APEPEPPPADDSPAEP 691
+ TP+ K ++ P PE + EP P ++SP EP
Sbjct: 853 TTSEVSTPTTT--KEPTTIHKSPDESTPELSAEPTPKALENSPKEP 896
Score = 110 bits (274), Expect = 2e-23
Identities = 137/577 (23%), Positives = 188/577 (32%), Gaps = 56/577 (9%)
Query: 388 EEMMPAAEKEEAKLPPPPLTPP----APSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPS 443
+E P KE A P TP AP+ P P +T P P P + P P+
Sbjct: 348 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 407
Query: 444 PPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTAT 503
P PA +E P + + + P TP + A P T+P PTP+T
Sbjct: 408 TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP--TTPKEPTPTT-- 463
Query: 504 GGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVL 563
P E +PT + T K P +A TP+ E P PK
Sbjct: 464 --PKEPAPTTKEPAPTTPKE------PAPTAPKKPAPTTPK----EPAPTTPKEPAPTTT 511
Query: 564 RPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRR-SILREPTFRWTSLTRELPPPP 622
+ P SP P+EPAP + APT P P K + +EP+ T P
Sbjct: 512 KEP---SPTTPKEPAPT-TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 567
Query: 623 PAP--PPPPAPSPPPAPA-TSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEP 679
PAP P PAP+ P PA T+ + P AP T A E T P AP P+
Sbjct: 568 PAPTTPKKPAPTTPKEPAPTTPKEP----APTTTKKPAPTTPKEPAPTTPKETAPTTPKK 623
Query: 680 EPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQ 739
P + A P T L P TP P+ A
Sbjct: 624 LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTT--------------PEEPAPTTP 669
Query: 740 PLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGVGSLPLSGVEEKMFSLLKRA 799
A T P P +P P P P E A G+ P + E + K A
Sbjct: 670 KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA 729
Query: 800 KVQLFKIDQQQQQKVAAS--MPLSPGGQMEEVAGAVKQISDRGPVRSEDESVEAKRERPS 857
+L ++ P +P G + + P + + +
Sbjct: 730 PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEP 789
Query: 858 GPESPVQGPRIKHVCRHAAVALGQARAMVPEDVPRLSALPLRDRQDLATEDTSSASETES 917
P +P + P K + + P P ++ T A T
Sbjct: 790 APTTP-KKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPE 848
Query: 918 VPSRSRRGKVEAAGPGGESEPTGSGGTLAHTPRRSLP 954
P + E + P EPT T+ +P S P
Sbjct: 849 TPPPTTS---EVSTPTTTKEPT----TIHKSPDESTP 878
Score = 98.2 bits (243), Expect = 1e-19
Identities = 106/423 (25%), Positives = 152/423 (35%), Gaps = 59/423 (13%)
Query: 367 EKKEEEEKDKE-GEEKEERAVAEEMMPAAEKEEAK-LPPPPLTPPAPSPPPPLPPPSTSP 424
E KE +K+ + +E+ + + + EK AK L P P+P +
Sbjct: 285 ETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPAL 344
Query: 425 PPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREA 484
P P P P P P P + + P T ++ P P+ +E
Sbjct: 345 TTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP 404
Query: 485 ARAGPEGTSPPT---PTPSTATGGP--PEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRV 539
A P+ +P T P P+T P P++ PK P +
Sbjct: 405 APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK------------PAPTTPKEPA 452
Query: 540 IKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEK 599
TP+ E P PK E +P + P +P P+EPAP APT P P P K
Sbjct: 453 PTTPK----EPTPTTPK-EPAPTTKEP---APTTPKEPAPTAPKKPAPTTPKEPAPTTPK 504
Query: 600 RRSILREPTFRWTSLTRELPPPPPAPPPP------PAPSPPPAPATSSRRPLLLRAPQFT 653
EP + T+E P P P P P + PAP T+ P + P T
Sbjct: 505 ------EPA---PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPT 555
Query: 654 PSEAHLKIYESVLTPPPLGAPEAPEPEPP-----PADDSPAEPEPRAVGRTNHLSLPRFA 708
++ E T P AP P+ P PA +P EP P + + A
Sbjct: 556 TTK------EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 609
Query: 709 PVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQ 768
P TTP E +P L+ P T +L P+ L P P+ P +P++
Sbjct: 610 P--TTP--KETAPTTPKKLT--PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE 663
Query: 769 MPP 771
P
Sbjct: 664 PAP 666
Score = 74.7 bits (182), Expect = 1e-12
Identities = 111/488 (22%), Positives = 162/488 (33%), Gaps = 70/488 (14%)
Query: 157 KTTPLPPPRLADVAPTPPKTPARKRGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTP 216
K TP P +LA PT P+ PA EE + T AP P++ A P+TP
Sbjct: 623 KLTPTTPEKLA---PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA--PNTP 677
Query: 217 RRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGP 276
+ P PA ++ E A T PK P + KE P P
Sbjct: 678 KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTL------------KE---PAP 722
Query: 277 GTPRRGGQSSRGGRGGRGRGRGGGLPFVIKFVSRAKKVKMGQLSLGLESGQGQGQHEESW 336
TP++ P K + K + G +E
Sbjct: 723 TTPKKPAPKELA-------------PTTTKEPTSTTCDKPAPTT---PKGTAPTTPKEPA 766
Query: 337 QDVPQRRVGSG-QGGSPCWKKQEQKLDDEEEEKKEEEEKDKEG-----EEKEERAVAEEM 390
P+ + +G +P K+ ++ KE +G +K +E
Sbjct: 767 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 826
Query: 391 MPAAEKEEAKLPPPPLTPPAPSPPPP-LPPPSTSP-------PPPLCPPPPPPVSPPPLP 442
P KE P P TP P+P P PPP+TS P P S P L
Sbjct: 827 APTTPKE-----PAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELS 881
Query: 443 SPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQR---AEREAARAGPEGTSPPTPTP 499
+ P P A E + P VP T + +P +T + + ER+ T+ P T
Sbjct: 882 AEPTPKALENSPKEPG--VPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTK 939
Query: 500 STATGGPPEDSPTVAPKSTTFLKNIRQFIMPV------VSARSSRVIKTPRRFMDEDPPK 553
TAT + +T Q P + + +V T + +
Sbjct: 940 ETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMN 999
Query: 554 PPKVEVSPVLRPPIT-TSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWT 612
P+ P R + + P PQ+P P P + P T +P R+ + T
Sbjct: 1000 KPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKT---MPRVRKPKTTPTPRKMT 1056
Query: 613 SLTRELPP 620
S EL P
Sbjct: 1057 STMPELNP 1064
Score = 72.4 bits (176), Expect = 6e-12
Identities = 142/647 (21%), Positives = 198/647 (30%), Gaps = 87/647 (13%)
Query: 1797 AAEENQTIVHSPA----PSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSA 1852
+A+E Q+I + A P+S+ P +T P P P P S +
Sbjct: 306 SAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTT--PKEPASTTP 363
Query: 1853 PPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPA---- 1908
P P + A P P S P +P++ PT P
Sbjct: 364 KEPTPTTIKSA----PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKE 419
Query: 1909 PPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPP 1968
P + + +P P+ P P T+P + P PT+ T E AP P+P
Sbjct: 420 PAPTTTKSAPTTPKEPAPTTPKKPAPTTP--KEPAPTTPKEPTPTTPKEPAPTTKEPAPT 477
Query: 1969 PPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEES 2028
P++ P A EP ++ P ++ +E
Sbjct: 478 TPKEPAPTAPKKP-------------APTTPKEPAP----------TTPKEPAPTTTKEP 514
Query: 2029 SPTSRYIHFPVTVVSAPGL----APSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTP 2084
SPT+ P T SAP AP+ T AP + + ++P T
Sbjct: 515 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP--TT 572
Query: 2085 PSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGG--PGDGGAGPREESLPPAPPL 2142
P P A P P E K P + +E+ P P
Sbjct: 573 PKKP---------APTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKK 623
Query: 2143 ANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFV 2202
+ P + +P P T AP PE P P T K N
Sbjct: 624 LTPTTPEKLAPTTPEKPAPTTPE-ELAPTTPEEPTPTTPEEPAPTTPKAAAPN------- 675
Query: 2203 KMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTL 2262
E P P P P +PT P T P P G P + PAP P P
Sbjct: 676 -TPKEPAPTTPKEPAPTTPKEPAPTTPKE-TAPTTP-KGTAPTT-LKEPAPTTPKKPAPK 731
Query: 2263 VLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDED--------------GEASE 2308
L+ P K T + P P AP ++ E +
Sbjct: 732 ELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP 791
Query: 2309 DTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGE--PAGEESPGPLQERSPLLPLPEDGP 2366
TP+ P + + T T P E P + P P + P PE P
Sbjct: 792 TTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPP 851
Query: 2367 PQVPD-GPPDLLLESQWHHYSGEASSSE-EEPPSPDDKENQAPKRTG 2411
P + P E H S + S+ E P+P EN +PK G
Sbjct: 852 PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALEN-SPKEPG 897
Score = 68.6 bits (166), Expect = 8e-11
Identities = 124/588 (21%), Positives = 178/588 (30%), Gaps = 56/588 (9%)
Query: 1790 EEPAHLEAAEENQTIVHSPAPS---SEPPGGEDPPLDTDVLVPGAPERHSPIQNLDP--- 1843
+EP E T P P+ S P ++P T P P+ +P +P
Sbjct: 348 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 407
Query: 1844 -PLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPS-PGSPSSLTHHIPTV 1901
P P + PAP + A + + P P P+ P P+ T PT
Sbjct: 408 TPKEPAPTTTKEPAPTTTKSAP------TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTP 461
Query: 1902 GDPDFPAP------PRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTS 1955
P PAP P + P+P AP+ P P T+P + P PT+ T
Sbjct: 462 TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTP--KEPAPTTTKEPSPTTP 519
Query: 1956 GELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGS 2015
E AP +P ++ P + + T +
Sbjct: 520 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 579
Query: 2016 SHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAV 2075
+ P ++ +E +PT+ T AP P P+ T + E +
Sbjct: 580 TPKEPAPTTPKEPAPTT-------TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL 632
Query: 2076 QQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREES 2135
+ P+ P + A P P E P A
Sbjct: 633 APTTPEKPAPTTPEEL------APTTPEEPTPTTPEE---------PAPTTPKAAAPNTP 677
Query: 2136 LPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVN 2195
PAP P+ +P P T P L PAP PK K +
Sbjct: 678 KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK-EPAPTTPKKPAPKELAPT 736
Query: 2196 KLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLL--GVLPVVGVVRPAP 2253
+ + P P P P +PT P P P G P + PAP
Sbjct: 737 TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKE----PAPTTPKGTAPTT-LKEPAP 791
Query: 2254 PPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQV 2313
P P L+ P K T + P P AP + + + TP+
Sbjct: 792 TTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPK--KPAPTTPET 849
Query: 2314 PGLGSGGFSR-VRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLP 2360
P + S K PT + E + E +P L E SP P
Sbjct: 850 PPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKAL-ENSPKEP 896
Score = 67.0 bits (162), Expect = 2e-10
Identities = 112/481 (23%), Positives = 162/481 (33%), Gaps = 55/481 (11%)
Query: 1790 EEPAHLEAAEENQTIVHSPAPSSEPPGGEDP----PLDTDVLVPGAPERHSPIQNLDPP- 1844
+EPA E T PAP+++ P P P P P+ +P +P
Sbjct: 449 KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP 508
Query: 1845 ---LRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTV 1901
P + PAP + A P + P S P SP++ PT
Sbjct: 509 TTTKEPSPTTPKEPAPTTTKSA----PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT 564
Query: 1902 GDPDFPAP-------PRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVP--PPTSVVTA-- 1950
P PAP P + P+P P+ P P T+P+ P P + T
Sbjct: 565 --PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK 622
Query: 1951 -LTPTSGE-LAPPGP-APSPPPPEDLGPDF-EDMEVVSGLSAADLDFAASLLGTEPFQEE 2006
LTPT+ E LAP P P+P PE+L P E+ + A A+ T
Sbjct: 623 KLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP 682
Query: 2007 IVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQL--DGV 2064
++ P ++ +E++PT+ P T+ AP+ TP P ++L
Sbjct: 683 TTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP---APT-TPKKPAPKELAPTTT 738
Query: 2065 DDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGP 2124
+ T + + +GT P+ P A P P LK
Sbjct: 739 KEPTSTTCDKPAPTTPKGTAPTTPKE------PAPTTPKEPAPTTPKGTAPTTLKEPAPT 792
Query: 2125 GDGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLP--GAPGVRVLSLGPAPE 2182
P+E AP G + +P P T P AP PE
Sbjct: 793 TPKKPAPKE----LAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPE 848
Query: 2183 PPKPATSKII--LVNKLGQVFVKMAGE------GEPVPPPVKQPPLPPTISPTAPTSWTL 2234
P P TS++ K K E EP P ++ P P + T + T
Sbjct: 849 TPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATK 908
Query: 2235 P 2235
P
Sbjct: 909 P 909
Score = 60.1 bits (144), Expect = 3e-08
Identities = 122/607 (20%), Positives = 179/607 (29%), Gaps = 116/607 (19%)
Query: 370 EEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPST------- 422
E E+ +E + + ++ P E A++ P P + PPP T
Sbjct: 76 ESFERGRECDCDAQCKKYDKCCPDYESFCAEVHNPTSPPSSKKAPPPSGASQTIKSTTKR 135
Query: 423 SPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRK-------------- 468
SP PP + + +E S ++ RK
Sbjct: 136 SPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQ 195
Query: 469 -----------RGRPPLTPSQRAEREAARAGPEG----TSPPTPT---------PSTATG 504
R + TP EA G T+P T T P T
Sbjct: 196 KKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTA 255
Query: 505 GPPEDSPTVAPKS----------------------TTFLKNIRQFIMPVVSAR------- 535
P P++ P S TT + SA+
Sbjct: 256 KPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEK 315
Query: 536 -SSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTP----- 589
S++ + + + + PK P L P +P P+EPA + P+ PTP
Sbjct: 316 TSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPA--STTPKEPTPTTIKS 373
Query: 590 -PSTP-VPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPP------------------- 628
P+TP P P +S P + T+E P P P P
Sbjct: 374 APTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPK 433
Query: 629 -PAPSPPPAPATSSRRPLLLRAPQ----FTPSEAHLKIYESVLTPPPLGAPEAPEPEPP- 682
PAP+ P PA ++ + P+ TP E E T P AP AP+ P
Sbjct: 434 EPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT 493
Query: 683 ----PADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKA---EVSPHGAPALSNGPQTQA 735
PA +P EP P + + AP T E +P + P+ +
Sbjct: 494 TPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPS 553
Query: 736 QLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGVGSLPLSGVEEKMFSL 795
A T P P +P P P P E A P + E +
Sbjct: 554 PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP 613
Query: 796 LKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISDRGPVRSEDESVEAKRER 855
+ A K+ +K+A + P P E E K
Sbjct: 614 KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA 673
Query: 856 PSGPESP 862
P+ P+ P
Sbjct: 674 PNTPKEP 680
Score = 57.8 bits (138), Expect = 1e-07
Identities = 105/513 (20%), Positives = 165/513 (32%), Gaps = 81/513 (15%)
Query: 1918 PLAPRP--PPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGP 1975
P+ PRP PP+ S L V T+V T T T+ + + ++
Sbjct: 257 PINPRPSLPPNSDTSK----ETSLTVNKETTVETKETTTTNK-------QTSTDGKEKTT 305
Query: 1976 DFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYI 2035
++ + + SA DL + +L + E G ++ P ++ +E + T+
Sbjct: 306 SAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKE 365
Query: 2036 HFPVTVVSAPGL----APSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVV 2091
P T+ SAP AP+ T AP + + ++P T P
Sbjct: 366 PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT 425
Query: 2092 RAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQG 2151
++ P E P+ P++ + P P + P +
Sbjct: 426 KSA-------PTTPKEPAPTT------------------PKKPA-PTTPKEPAPTTPKEP 459
Query: 2152 LTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPV 2211
+P +P T AP AP+ P P T K EP
Sbjct: 460 TPTTPKEPAPTTK--EPAPTTPKEPAPTAPKKPAPTTPK------------------EPA 499
Query: 2212 PPPVKQP-------PLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVL 2264
P K+P P P T APT+ P P P P P P T
Sbjct: 500 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP-TTTK 558
Query: 2265 SSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRV 2324
P +P A + + PAP K P + + TP+ P +
Sbjct: 559 EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP-----TTP 613
Query: 2325 RMKTPTVRGVLDLDRPGE--PAGEESPGPLQERSPLLPLPEDGPPQVPDGPPDLLLESQW 2382
+ PT L P + P E P P PE+ P P+ P ++
Sbjct: 614 KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA 673
Query: 2383 HHYSGEASSSEEEPPSPDDKENQA---PKRTGP 2412
+ E + + + P+P + A PK T P
Sbjct: 674 PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 706
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 112 bits (279), Expect = 6e-24
Identities = 113/389 (29%), Positives = 130/389 (33%), Gaps = 89/389 (22%)
Query: 390 MMPAAEKEEAKLPPPPLTPPAPSPPP--------PLPPP---STSPPPPLCP----PPPP 434
++P A +PPPP P A PPP PLPPP + PPPP P PPPP
Sbjct: 931 ILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPP 990
Query: 435 PV------SPPPLPS---PPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAA 485
P+ PPPLP PPPPP PPP+ A G PP P A
Sbjct: 991 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA------GIPPPPPLPGA----- 1039
Query: 486 RAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRR 545
G PP P P PP P P+ A P
Sbjct: 1040 -----GIPPPPPLPGAGIPPPPPLPGAGIPPPP-----------PLPGAGIPPPPPLPGA 1083
Query: 546 FMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAP---TPPSTPVPLPEKRRS 602
+ PP P P P + PP P A +P PP P PP P+P
Sbjct: 1084 GIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP------- 1136
Query: 603 ILREPTFRWTSLTRELPPPPP-----APPPPPAPS-----PPPAPATSSRRPLLLRAPQF 652
+PPPPP PPPPP P PPP P P L
Sbjct: 1137 ------------GAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGI 1184
Query: 653 TPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVT 712
P + + PPPL P P P P P P P + P PV
Sbjct: 1185 PPPPPLPGV--GIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSG 1242
Query: 713 TPVKAEVSPHGAPALSNGPQTQAQLLQPL 741
P+ +V P PQ L PL
Sbjct: 1243 PPLLPQVGSSTLPT----PQVCGFLPPPL 1267
Score = 110 bits (276), Expect = 1e-23
Identities = 118/408 (28%), Positives = 133/408 (32%), Gaps = 110/408 (26%)
Query: 402 PPPPLTPPAPSPPPPLP----------PPSTSPPPPLCP----PPPPPVS------PPPL 441
PPPPL PPPPLP P + PPPP P PPPPP+ PPPL
Sbjct: 911 PPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPL 970
Query: 442 PS---PPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPT 498
P PPPPP PPP+ A G PP P A G PP P
Sbjct: 971 PGAGIPPPPPLPGAGIPPPPPLPGA------GIPPPPPLPGA----------GIPPPPPL 1014
Query: 499 PSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVE 558
P PP P+ A P + PP P
Sbjct: 1015 PGAGIPPPP----------------------PLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1052
Query: 559 VSPVLRPPITTSPPVPQEPAPVPSPPRAP---TPPSTPVPLPEKRRSILREPTFRWTSLT 615
P P PP P A +P PP P PP P+P
Sbjct: 1053 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP-------------------G 1093
Query: 616 RELPPPPP-----APPPPPAPS-----PPPAPATSSRRPLLLRAPQFTPSEAHLKIYESV 665
+PPPPP PPPPP P PPP P P L P ++ +
Sbjct: 1094 AGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRV--GI 1151
Query: 666 LTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAP 725
PPPL P P P P P P VG + P P V P + G P
Sbjct: 1152 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVG----IPPPPPLPGVGIPPPPPLPGAGIP 1207
Query: 726 ALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPP-SPQQMPPL 772
P + P A LPPP + PPP P PPL
Sbjct: 1208 P---PPPLPGMGIPPAPA-------PPLPPPGTGIPPPPLLPVSGPPL 1245
Score = 84.0 bits (206), Expect = 2e-15
Identities = 122/498 (24%), Positives = 152/498 (30%), Gaps = 138/498 (27%)
Query: 376 KEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLC------ 429
+E E + R + + + + EE + P P PP P + P C
Sbjct: 729 EEKEVRHHRILEAKSIQTSPTEEGGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLI 788
Query: 430 ---------------------PPPPP----------PVSPPP------------------ 440
PPPPP P S PP
Sbjct: 789 VSPRRISVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSA 848
Query: 441 ------LPSPPPPPAQEEQEE--------SPPPVVPATCSRKRGRPPLTPSQRAEREAAR 486
+PSPPP P E PPP +P P PS +
Sbjct: 849 FKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGM------TVPTLPSTAIPQPPPL 902
Query: 487 AGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRF 546
G E PP P P G PP P P + I+P+ + + P
Sbjct: 903 QGTE-MLPPPPPPLPGAGIPP---PPPLPGAG---------ILPLPPLPGAGIPPPPPLP 949
Query: 547 MDEDPPKPPKVEVSPVLRPPITTS---PPVPQEPAPVPSPPRAP---TPPSTPVPLPEKR 600
PP PP L PP+ + PP P A +P PP P PP P+P
Sbjct: 950 GAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP----- 1004
Query: 601 RSILREPTFRWTSLTRELPPPPP-----APPPPPAPS-----PPPAPATSSRRPLLLRAP 650
+PPPPP PPPPP P PPP P P L
Sbjct: 1005 --------------GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1050
Query: 651 QFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPV 710
P PPP P A P PPP + P P G + P P
Sbjct: 1051 GIPPPPP----LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA--GIPPPPPLPG 1104
Query: 711 VTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMP 770
V P + G P P + P L +P PPP P++ PP P
Sbjct: 1105 VGIPPPPPLPGAGIPP---PPPLPGAGIPPPPPLPGAGIPP--PPPLPRVGIPPP----P 1155
Query: 771 PLEKARIAGVGSLPLSGV 788
PL A I LP +G+
Sbjct: 1156 PLPGAGIPPPPPLPGAGI 1173
Score = 79.3 bits (194), Expect = 5e-14
Identities = 146/569 (25%), Positives = 186/569 (32%), Gaps = 144/569 (25%)
Query: 1814 PPGGEDPPLD---TDVLVPGAPER-------HSPIQNLDPPLRPDS----------GSAP 1853
PPG E P +++ + +P R H P Q++ P P S GS P
Sbjct: 770 PPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQP 829
Query: 1854 PPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRS 1913
P + + + S + S PLP S SS+ P +G P PP
Sbjct: 830 PHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSM----PGLGMVPPPPPPLPG 885
Query: 1914 RR----PSPLAPRPPP---SRWASPPLKTSPQLRVPPPTSV----VTALTPTSGELAPPG 1962
PS P+PPP + PP P +PPP + + L P G PP
Sbjct: 886 MTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPP 945
Query: 1963 P----APSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHG 2018
P A PPPP L A + L G + +
Sbjct: 946 PPLPGAAIPPPPP--------------LPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPP 991
Query: 2019 GPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQP 2078
PG I P + A P PGA G+ + P
Sbjct: 992 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA-------GIPPPPPLPGAGIPPP 1044
Query: 2079 R---GQGTPPSGP----GVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGP 2131
G G PP P G+ L AG PP LP + P GAG
Sbjct: 1045 PPLPGAGIPPPPPLPGAGIPPPPPLPGAG--IPPPPPLPGAGIP------PPPPLPGAG- 1095
Query: 2132 REESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKI 2191
+PP PPL P G+ P P P PG G P PP P
Sbjct: 1096 ----IPPPPPL-----PGVGIPPPPPLPGAGIPPPPPLPGA-----GIPPPPPLP----- 1136
Query: 2192 ILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGV-----LPVV 2246
G G P PPP+ + +PP P P + PP PL G P+
Sbjct: 1137 --------------GAGIPPPPPLPRVGIPPP--PPLPGAGIPPPPPLPGAGIPPPPPLP 1180
Query: 2247 GVVRPAPP-------PPPPPLTLVLSSG-PASPPRQAIRVKRVSTFSGRSPPAPPPYKA- 2297
GV P PP PPPPPL +G P PP + + +PP PPP
Sbjct: 1181 GVGIPPPPPLPGVGIPPPPPLP---GAGIPPPPPLPGMGIP-----PAPAPPLPPPGTGI 1232
Query: 2298 -----------PRLDEDGEASEDTPQVPG 2315
P L + G ++ TPQV G
Sbjct: 1233 PPPPLLPVSGPPLLPQVGSSTLPTPQVCG 1261
Score = 69.7 bits (169), Expect = 4e-11
Identities = 103/358 (28%), Positives = 121/358 (33%), Gaps = 62/358 (17%)
Query: 2043 SAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGT---PPSGPGVVRAGVLGAA 2099
S PGL P P L G+ T Q P QGT PP P + AG+
Sbjct: 869 SMPGLGMVPPPPPP----LPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGI---- 920
Query: 2100 GDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPRE-ESLPPAPPLANGSQPSQGLTASPAD 2158
PP LP + L L G G P ++PP PPL P G+ P
Sbjct: 921 ----PPPPPLPGAGI-LPLPPLPGAGIPPPPPLPGAAIPPPPPL-----PGAGIPLPPPL 970
Query: 2159 PTRTFAWLPGAPGVRVLSLGPAP----EPPKPATSKIILVNKLGQVFVKMAGEGEPVPPP 2214
P P PG + P P PP P I + G G P PPP
Sbjct: 971 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP------PLPGAGIPPPPP 1024
Query: 2215 VKQPPLPPTISPTAPTSWTLPPGPLLGV-----LPVVGVVRPAPP-------PPPPPLTL 2262
+ +PP P P + PP PL G P+ G P PP PPPPPL
Sbjct: 1025 LPGAGIPPP--PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP- 1081
Query: 2263 VLSSG-PASPPRQAIRVKRVSTFSGRSPPAPPPYKA----PRLDEDGEASEDTPQVPGLG 2317
+G P PP + G P PPP P G P +PG G
Sbjct: 1082 --GAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1139
Query: 2318 SGGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQERS--PLLPLPEDGPPQVPDGP 2373
+ P R + P AG P PL P PLP G P P P
Sbjct: 1140 ------IPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLP 1191
Score = 69.3 bits (168), Expect = 5e-11
Identities = 132/476 (27%), Positives = 155/476 (32%), Gaps = 142/476 (29%)
Query: 1808 PAPSSEPPGGEDPPLDTDVLVPGA---PERHSPIQNLDPPLRPDSGSAPPPAPRSFSGAR 1864
P P P G PP +PGA P P + PP + PPP P GA
Sbjct: 910 PPPPPLPGAGIPPPPP----LPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPP--LPGAG 963
Query: 1865 IKVPNYSPSRRPLGGVSFGPLPS-PGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRP 1923
I +P PL G P P PG+ +P G P P PP P P P
Sbjct: 964 IPLPP------PLPGAGIPPPPPLPGAGIPPPPPLPGAGIP--PPPPL----PGAGIPPP 1011
Query: 1924 PPSRWAS-PPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPS---PPPPEDLGPDFED 1979
PP A PP P +PPP + P +G + PP P P PPPP G
Sbjct: 1012 PPLPGAGIPPPPPLPGAGIPPPPPL-----PGAG-IPPPPPLPGAGIPPPPPLPGAGIPP 1065
Query: 1980 MEVVSGLSAADLDFAASLLGTE-PFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFP 2038
+ G A + L G P + AG P
Sbjct: 1066 PPPLPG---AGIPPPPPLPGAGIPPPPPLPGAGIPPPP---------------------P 1101
Query: 2039 VTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQP---RGQGTPPSGPGVVRAGV 2095
+ V P P G P L G + P G G PP P + R G+
Sbjct: 1102 LPGVGIPPPPPLPGAGIPPPPPLPGA---------GIPPPPPLPGAGIPPP-PPLPRVGI 1151
Query: 2096 LGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTAS 2155
PP LP GAG +PP PPL P G+
Sbjct: 1152 --------PPPPPLP-----------------GAG-----IPPPPPL-----PGAGIPPP 1176
Query: 2156 PADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPV 2215
P P P PGV G P PP P G G P PPP+
Sbjct: 1177 PPLPGVGIPPPPPLPGV-----GIPPPPPLP-------------------GAGIPPPPPL 1212
Query: 2216 KQPPLPPTISPTAPTSWT-LPPGPLLGV-----LPVVG-VVRPAP------PPPPP 2258
+PP +P P T +PP PLL V LP VG P P PPP P
Sbjct: 1213 PGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLP 1268
Score = 54.3 bits (129), Expect = 2e-06
Identities = 63/233 (27%), Positives = 79/233 (33%), Gaps = 48/233 (20%)
Query: 2156 PADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPV 2215
P T + + +PG L + P P PP P G + P PPP+
Sbjct: 860 PLPCTESSSSMPG------LGMVPPPPPPLP-----------GMTVPTLPSTAIPQPPPL 902
Query: 2216 KQPPLPPTISPTAPTSWTLPPGPLLG-----VLPVVGVVRPAPP-------PPPPPLTLV 2263
+ + P P P + PP PL G + P+ G P PP PPPPPL
Sbjct: 903 QGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLP-- 960
Query: 2264 LSSG-PASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFS 2322
+G P PP + G P PPP G P +PG G
Sbjct: 961 -GAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPL-------PGAGIPPPPPLPGAG----- 1007
Query: 2323 RVRMKTPTVRGVLDLDRPGEPAGEESPGPLQERS--PLLPLPEDGPPQVPDGP 2373
+ P + P AG P PL P PLP G P P P
Sbjct: 1008 -IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1059
Score = 49.7 bits (117), Expect = 4e-05
Identities = 32/79 (40%), Positives = 35/79 (44%), Gaps = 6/79 (7%)
Query: 401 LPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPP--PVSPPPLPSPPPPPAQEEQEESPP 458
+PPPP P A PPPP P PP P P PPP + PPPL PP + S
Sbjct: 1195 IPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTL 1254
Query: 459 PVVPATCSRKRGRPPLTPS 477
P P C PP PS
Sbjct: 1255 P-TPQVCG---FLPPPLPS 1269
Score = 48.9 bits (115), Expect = 7e-05
Identities = 49/163 (30%), Positives = 56/163 (34%), Gaps = 18/163 (11%)
Query: 1808 PAPSSEPPGGEDPPLDTDVLVPGA---PERHSPIQNLDPPLRPDSGSAPPPAPRSFSGAR 1864
P P P G PP +PGA P P + PP PPP P +G
Sbjct: 1119 PPPPPLPGAGIPPPPP----LPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGI- 1173
Query: 1865 IKVPNYSPSRRPLGGVSFGPLPS-PGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRP 1923
P PL GV P P PG +P G P P P P+P P P
Sbjct: 1174 -------PPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLP 1226
Query: 1924 PPSRWASPP--LKTSPQLRVPPPTSVVTALTPTSGELAPPGPA 1964
PP PP L S +P S G L PP P+
Sbjct: 1227 PPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPS 1269
Score = 43.1 bits (100), Expect = 0.004
Identities = 60/257 (23%), Positives = 86/257 (33%), Gaps = 73/257 (28%)
Query: 2147 QPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNK--LGQVFVKM 2204
QP+Q ++ P P+ ++ G PG +PP +++ ++ + F
Sbjct: 802 QPTQSISQPPPPPSLLWSAGQGQPG---------SQPPHSISTEFQTSHEHSVSSAFKNS 852
Query: 2205 AGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPP--------- 2255
+P P PPLP T S ++ +P +G+V P PPP
Sbjct: 853 CN----IPSP---PPLPCTESSSS--------------MPGLGMVPPPPPPLPGMTVPTL 891
Query: 2256 -----------------PPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAP 2298
PPPP L + P PP + + G P PPP
Sbjct: 892 PSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPL--- 948
Query: 2299 RLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQERS-- 2356
G A P +PG G + + P + P AG P PL
Sbjct: 949 ----PGAAIPPPPPLPGAG------IPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 998
Query: 2357 PLLPLPEDGPPQVPDGP 2373
P PLP G P P P
Sbjct: 999 PPPPLPGAGIPPPPPLP 1015
Score = 34.3 bits (77), Expect = 1.7
Identities = 76/306 (24%), Positives = 97/306 (31%), Gaps = 55/306 (17%)
Query: 2094 GVLGAAGDRARPPE---------DLPSEIVDFVLKNLGGPGDGGAGPREE-SLPPAPPLA 2143
G G AG+ P+ DLP + + P GG E SLP A P A
Sbjct: 255 GPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAA 314
Query: 2144 NGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVK 2203
S S A P A GAP V G E + + G+ +
Sbjct: 315 KDSPSSTAFPFPEAGPGEEAA---GAP---VRGAGDTDEEGEEDAFEDAPRGSPGEEWAP 368
Query: 2204 MAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPP---PPL 2260
GE P + + P P AP + +LP P P +P P P
Sbjct: 369 EVGED--APQRLGEEPEEEAQGPDAPAAASLPGSP----APSQRCFKPYPLITPCYIKTT 422
Query: 2261 TLVLSS---GPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLG 2317
T LSS P+ P Q+ R+KR P R AS P
Sbjct: 423 TRQLSSPNHSPSQSPNQSPRIKR-----------RPEPSLSRGSRTALASVAAPAKKHRA 471
Query: 2318 SGGFS-----------RVRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLPLPEDGP 2366
GG + + +TP V G L G +S G + SP L G
Sbjct: 472 DGGLAAGLSRSADWTEELGARTPRVGGSAHLLERG--VASDSGGGV---SPALAAKASGA 526
Query: 2367 PQVPDG 2372
P DG
Sbjct: 527 PAAADG 532
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 111 bits (278), Expect = 8e-24
Identities = 114/384 (29%), Positives = 140/384 (36%), Gaps = 97/384 (25%)
Query: 404 PPLTPPA-----------PSPPPPLPPPS----TSPPPPL---CPPPPPPVSPPPLPSPP 445
PPL PP PS P P PS + PP P PPP P V P PP
Sbjct: 126 PPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPP 185
Query: 446 PPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTP-TPSTATG 504
P P+ +S P RG PP+ R + P T PP P TA G
Sbjct: 186 PVPSTPRPIQSSP--------HNRGSPPVPGGPR------QPSPGPTPPPFPGNRGTALG 231
Query: 505 GPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSR--VIKTPRRFMDEDPPKPPKVEVSPV 562
G +IRQ + S S+R + TP R +D+ PP PP
Sbjct: 232 GG----------------SIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPP------- 268
Query: 563 LRPPITTSPPVPQEPAPVPSPPRAPTP-PSTPVPLPEKRRSILREPTFRWTSLTRELPPP 621
PP+ P + +E P P P P PSTP P S + + PPP
Sbjct: 269 --PPVGNRPSIHREAVPPPPPQNNKPPVPSTPRP-----------------SASSQAPPP 309
Query: 622 PPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEP 681
PP PP P PPP P +SS R PQ +L + S PPL +P P P
Sbjct: 310 PP---PPSRPGPPPLPPSSSGNDETPRLPQ-----RNLSLSSST---PPLPSPGRSGPLP 358
Query: 682 PPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPL 741
PP + P P GR+ L P P V+ + P L + + P
Sbjct: 359 PPPSERPPPPVRDPPGRSGPLPPP---PPVSRNGSTSRALPATPQLPSRSGVDSPRSGPR 415
Query: 742 QALQTQLLPQALPPPQPQLQPPPS 765
L PPP PPPS
Sbjct: 416 PPLPPDRPSAGAPPP-----PPPS 434
Score = 90.9 bits (224), Expect = 2e-17
Identities = 104/346 (30%), Positives = 118/346 (34%), Gaps = 72/346 (20%)
Query: 392 PAAEKEEAKLPPPPLTP---PAPSP--------------PPPLPPPSTSP---PPPLCPP 431
P AK PP P P PSP PPP P + P PPP+
Sbjct: 131 PGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPST 190
Query: 432 PPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEG 491
P P S P PP P Q SP P P RG L + + + P
Sbjct: 191 PRPIQSSPHNRGSPPVPGGPRQ-PSPGP-TPPPFPGNRG-TALGGGSIRQSPLSSSSPFS 247
Query: 492 TSPP-TPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSS--RVIKTPRRFMD 548
PP PTPS A P P P V R S R P +
Sbjct: 248 NRPPLPPTPSRALDDKPPPPP------------------PPVGNRPSIHREAVPPPPPQN 289
Query: 549 EDPPKP--PKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILRE 606
PP P P+ S PP PP P P P P PP + TP LP++ S+
Sbjct: 290 NKPPVPSTPRPSASSQAPPP----PPPPSRPGPPPLPPSSSGNDETP-RLPQRNLSLSSS 344
Query: 607 -PTFRWTSLTRELPPPPPAPPPPPA----------PSPPPAPATSSRRPLLLRAPQFTPS 655
P + LPPPP PPPP P PPP S L PQ PS
Sbjct: 345 TPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQL-PS 403
Query: 656 EAHLKIYESVLTPP-PLGAPEAPEPEPPPA--------DDSPAEPE 692
+ + S PP P P A P PPP DSP E E
Sbjct: 404 RSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDE 449
Score = 85.5 bits (210), Expect = 6e-16
Identities = 130/519 (25%), Positives = 169/519 (32%), Gaps = 134/519 (25%)
Query: 1960 PPGPAPSPPPPEDLG----PDFEDMEVVSGLSA--ADLDFAASLLGT------EPFQEEI 2007
PP PAP PPP L P E +G +A +D+ L T P ++
Sbjct: 4 PPPPAPPPPPTFALANTEKPTLNKTEQ-AGRNALLSDISKGKKLKKTVTNDRSAPILDKP 62
Query: 2008 VAAGA------------MGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGA 2055
AGA G GG G S P PGL G
Sbjct: 63 KGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGP--------------PGLGGLFQAGM 108
Query: 2056 PRIEQLDGVDDGTDSEAEAVQQPRGQGT------PPSGPGVV-------RAGV------- 2095
P++ D+ + + P G+ T PPSGPG R+G
Sbjct: 109 PKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNR 168
Query: 2096 -------LGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQP 2148
+G+ D PP + N G P G GPR+ S P PP G++
Sbjct: 169 MPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPG-GPRQPSPGPTPPPFPGNRG 227
Query: 2149 SQ----GLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKM 2204
+ + SP + F+ P P +L P PP P +++
Sbjct: 228 TALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHR-------- 279
Query: 2205 AGEGEPVPPPVK-QPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPP----- 2258
E P PPP +PP+P T P+A + PP P RP PPP PP
Sbjct: 280 --EAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPP---------PSRPGPPPLPPSSSGN 328
Query: 2259 ------------------PLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRL 2300
PL SGP PP V GRS P PPP P +
Sbjct: 329 DETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPP---PPV 385
Query: 2301 DEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLP 2360
+G S P P L P+ GV D P +G P P S P
Sbjct: 386 SRNGSTSRALPATPQL------------PSRSGV---DSP--RSGPRPPLPPDRPSAGAP 428
Query: 2361 LPEDGPPQVPDGPPDLLLESQWHHYSGEASSSEEEPPSP 2399
P + +G D E +W S+ PP P
Sbjct: 429 PPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEP 467
Score = 83.2 bits (204), Expect = 3e-15
Identities = 79/275 (28%), Positives = 97/275 (35%), Gaps = 67/275 (24%)
Query: 404 PPLTPPAPS------PPPPLPPPSTSPP--PPLCPPPPPPVSPPPLPSPPPPPAQEEQEE 455
PPL PP PS PPPP PP P PPPPP + PP+PS P P A +
Sbjct: 250 PPL-PPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPP 308
Query: 456 SPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAP 515
PPP + G PPL PS E R P S ++ PP SP
Sbjct: 309 PPPP------PSRPGPPPLPPSSSGNDETPRL-------PQRNLSLSSSTPPLPSP---- 351
Query: 516 KSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQ 575
RS + P PP P +R P P
Sbjct: 352 ------------------GRSGPL------------PPPPSERPPPPVRDP-------PG 374
Query: 576 EPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPP 635
P+P PP ST LP + + P+ R P PP P P A +PPP
Sbjct: 375 RSGPLPPPPPVSRNGSTSRALP----ATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPP 430
Query: 636 APATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPP 670
P ++S R +P E+ + PPP
Sbjct: 431 PPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPP 465
Score = 76.6 bits (187), Expect = 3e-13
Identities = 82/317 (25%), Positives = 112/317 (35%), Gaps = 68/317 (21%)
Query: 470 GRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIM 529
G P L + + ++ G+ PP P + SP P +F +
Sbjct: 107 GMPKLRSTANRDNDSG-----GSRPPLLPPGGRSTSAKPFSPPSGPG---------RFPV 152
Query: 530 PVVSARSSRVIKTPRRFMDEDPPKPPKVEVSP-VLRPPITTSP-PVPQEP-----APVPS 582
P RS P + PP P V P + PP+ ++P P+ P PVP
Sbjct: 153 PSPGHRSG----PPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPG 208
Query: 583 PPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPS------PPPA 636
PR P+P TP P P R + L + R + L+ P PP PP PS PPP
Sbjct: 209 GPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSS-SPFSNRPPLPPTPSRALDDKPPPP 267
Query: 637 PATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPP-PADDSPAEPEPRA 695
P RP I+ + PPP + P P P P+ S A P P
Sbjct: 268 PPPVGNRP---------------SIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPP-- 310
Query: 696 VGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPP 755
P + P P S+G +L Q +L + P P
Sbjct: 311 ------------------PPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPG 352
Query: 756 PQPQLQPPPSPQQMPPL 772
L PPPS + PP+
Sbjct: 353 RSGPLPPPPSERPPPPV 369
Score = 68.2 bits (165), Expect = 1e-10
Identities = 98/379 (25%), Positives = 126/379 (33%), Gaps = 57/379 (15%)
Query: 1807 SPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPP--PAPRSFSGAR 1864
S P S P G P+ + G PE P +N PP RPD GS P P P +
Sbjct: 137 SAKPFSPPSGPGRFPVPSPGHRSGPPE---PQRNRMPPPRPDVGSKPDSIPPPVPSTPRP 193
Query: 1865 IKVPNYSPSRRPLGGVSFGPLPSPGSP-----------------SSLTHHIPTVGDPDFP 1907
I+ ++ P+ G P P P P S L+ P P P
Sbjct: 194 IQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLP 253
Query: 1908 APPRRSRRPSPLAPRPP----PS--RWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPP 1961
P R+ P P PP PS R A PP PQ PP S T S + PP
Sbjct: 254 PTPSRALDDKPPPPPPPVGNRPSIHREAVPP--PPPQNNKPPVPS--TPRPSASSQAPPP 309
Query: 1962 GPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPG 2021
P PS P P L P + L +L ++S T P + + G G P
Sbjct: 310 PPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSS---TPP----LPSPGRSGPLPPPPS 362
Query: 2022 DSSEEE-SSPTSRYIHF-PVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAV--QQ 2077
+ P R P VS G A P P++ GVD + +
Sbjct: 363 ERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDR 422
Query: 2078 PRGQGTPPSGPGV-VRAGVLGAAGD-------------RARPPEDLPSEIVDFVLKNLGG 2123
P PP P +R G + + PPE + K
Sbjct: 423 PSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLARN 482
Query: 2124 PGDGGAGPREESLPPAPPL 2142
G+ RE PP PP+
Sbjct: 483 ESRSGSNRRERGAPPLPPI 501
Score = 64.7 bits (156), Expect = 1e-09
Identities = 65/178 (36%), Positives = 70/178 (39%), Gaps = 25/178 (14%)
Query: 1801 NQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSF 1860
N+ +H A PP PP VP P R S PP P S PPP P S
Sbjct: 273 NRPSIHREAVPPPPPQNNKPP------VPSTP-RPSASSQAPPPPPPPSRPGPPPLPPSS 325
Query: 1861 SGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLA 1920
SG + P P R S PLPSPG L P PP RS PL
Sbjct: 326 SG-NDETPRL-PQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRS---GPLP 380
Query: 1921 PRPPPSR--WASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGP------APSPPPP 1970
P PP SR S L +PQL P S V +P SG P P AP PPPP
Sbjct: 381 PPPPVSRNGSTSRALPATPQL---PSRSGVD--SPRSGPRPPLPPDRPSAGAPPPPPP 433
Score = 58.9 bits (141), Expect = 7e-08
Identities = 126/513 (24%), Positives = 172/513 (33%), Gaps = 126/513 (24%)
Query: 23 RPRGAGGGGGRGGRGNGAERVRVALRRGGGATGPGGAEPGEDTALLRLLGL-RRGLRRLR 81
+P+GAG GGG GG G G GGG+ G GG PG L GL + G+ +LR
Sbjct: 61 KPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFG-GGGPPG-------LGGLFQAGMPKLR 112
Query: 82 RL--------WAGPRVQRGRGRGRGR-----GWGPSRGCVPEEESSDGESDEEEFQ---- 124
+ P + GR GP R VP G + + +
Sbjct: 113 STANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPP 172
Query: 125 --GFHSDEDVAPSSLRSALRSQRGRAPRGRGRKHKTTPLP-PPRLADVAPTPPKTPARKR 181
S D P + S R + +P RG + P+P PR PTPP P
Sbjct: 173 RPDVGSKPDSIPPPVPSTPRPIQS-SPHNRG----SPPVPGGPRQPSPGPTPPPFP---- 223
Query: 182 GEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVVA 241
G GT ++ + + +P + +R P TP R+ P P P + +
Sbjct: 224 GNRGTALGGGSIRQSPLSSSSPFS--NRPPLPPTPSRALDDKPPPPPPPVGNRPS---IH 278
Query: 242 EAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGGL 301
AV P P+ P VP + + P P P P G
Sbjct: 279 REAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRP-------------------GPP 319
Query: 302 PFVIKFVSRAKKVKMGQLSLGLESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQKL 361
P + ++ Q +L L S S +P G+ G L
Sbjct: 320 PLPPSSSGNDETPRLPQRNLSLSS---------STPPLP----SPGRSG---------PL 357
Query: 362 DDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPS--------- 412
E+ +D G R+ P + + P TP PS
Sbjct: 358 PPPPSERPPPPVRDPPG-----RSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRS 412
Query: 413 -PPPPLPP--PSTSPPPPLCPPPPPPV------SP-----------PPLPSPPPPPAQEE 452
P PPLPP PS PPP PPP + SP P+ PPP +
Sbjct: 413 GPRPPLPPDRPSAGAPPP--PPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQ 470
Query: 453 QEESPPPVVPATCS------RKRGRPPLTPSQR 479
+S P + S R+RG PPL P R
Sbjct: 471 TTKSYPSKLARNESRSGSNRRERGAPPLPPIPR 503
Score = 55.5 bits (132), Expect = 7e-07
Identities = 64/226 (28%), Positives = 80/226 (35%), Gaps = 51/226 (22%)
Query: 1788 PREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNL-----D 1842
P P H E Q + P P G P D + P P PIQ+
Sbjct: 151 PVPSPGHRSGPPEPQ---RNRMPPPRPDVGSKP----DSIPPPVPSTPRPIQSSPHNRGS 203
Query: 1843 PPL-----RPDSGSAPPPAP----RSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSS 1893
PP+ +P G PPP P + G I+ S S P PS
Sbjct: 204 PPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDK 263
Query: 1894 LTHHIPTVGD-PDF------PAPPRRSRRPSPLAPRP-----------PPSRWASPPLKT 1935
P VG+ P P PP+ ++ P P PRP PPSR PPL
Sbjct: 264 PPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPP 323
Query: 1936 SPQ-----LRVPPPTSVVTALTP------TSGELAPPGPAPSPPPP 1970
S R+P +++ TP SG L PP P+ PPPP
Sbjct: 324 SSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPP-PSERPPPP 368
Score = 32.7 bits (73), Expect = 5.0
Identities = 41/153 (26%), Positives = 51/153 (33%), Gaps = 7/153 (4%)
Query: 1035 SPEASPGPPGPRRGAGAGGPREEVVAHPGPEEQDSLLQRK-SARRCVKQRPSYDIFEDSD 1093
S +A P PP P R GP + G +E L QR S PS
Sbjct: 303 SSQAPPPPPPPSRP----GPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLP 358
Query: 1094 DSEPGGPPAPRRRTP-RENELPLPEPEEQSRPRKPTLQPVLQLKARRRLDKDALAPGPFA 1152
PP P R P R LP P P ++ L QL +R +D P P
Sbjct: 359 PPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPL 418
Query: 1153 SFPNGWTGKQKSPDGVHRVRVDFKEDCDLENVW 1185
G P +R F +D E+ W
Sbjct: 419 PPDRPSAGAPPPPPPSTSIRNGF-QDSPCEDEW 450
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 111 bits (278), Expect = 8e-24
Identities = 114/384 (29%), Positives = 140/384 (36%), Gaps = 97/384 (25%)
Query: 404 PPLTPPA-----------PSPPPPLPPPS----TSPPPPL---CPPPPPPVSPPPLPSPP 445
PPL PP PS P P PS + PP P PPP P V P PP
Sbjct: 126 PPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPP 185
Query: 446 PPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTP-TPSTATG 504
P P+ +S P RG PP+ R + P T PP P TA G
Sbjct: 186 PVPSTPRPIQSSP--------HNRGSPPVPGGPR------QPSPGPTPPPFPGNRGTALG 231
Query: 505 GPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSR--VIKTPRRFMDEDPPKPPKVEVSPV 562
G +IRQ + S S+R + TP R +D+ PP PP
Sbjct: 232 GG----------------SIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPP------- 268
Query: 563 LRPPITTSPPVPQEPAPVPSPPRAPTP-PSTPVPLPEKRRSILREPTFRWTSLTRELPPP 621
PP+ P + +E P P P P PSTP P S + + PPP
Sbjct: 269 --PPVGNRPSIHREAVPPPPPQNNKPPVPSTPRP-----------------SASSQAPPP 309
Query: 622 PPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEP 681
PP PP P PPP P +SS R PQ +L + S PPL +P P P
Sbjct: 310 PP---PPSRPGPPPLPPSSSGNDETPRLPQ-----RNLSLSSST---PPLPSPGRSGPLP 358
Query: 682 PPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPL 741
PP + P P GR+ L P P V+ + P L + + P
Sbjct: 359 PPPSERPPPPVRDPPGRSGPLPPP---PPVSRNGSTSRALPATPQLPSRSGVDSPRSGPR 415
Query: 742 QALQTQLLPQALPPPQPQLQPPPS 765
L PPP PPPS
Sbjct: 416 PPLPPDRPSAGAPPP-----PPPS 434
Score = 90.9 bits (224), Expect = 2e-17
Identities = 104/346 (30%), Positives = 118/346 (34%), Gaps = 72/346 (20%)
Query: 392 PAAEKEEAKLPPPPLTP---PAPSP--------------PPPLPPPSTSP---PPPLCPP 431
P AK PP P P PSP PPP P + P PPP+
Sbjct: 131 PGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPST 190
Query: 432 PPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEG 491
P P S P PP P Q SP P P RG L + + + P
Sbjct: 191 PRPIQSSPHNRGSPPVPGGPRQ-PSPGP-TPPPFPGNRG-TALGGGSIRQSPLSSSSPFS 247
Query: 492 TSPP-TPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSS--RVIKTPRRFMD 548
PP PTPS A P P P V R S R P +
Sbjct: 248 NRPPLPPTPSRALDDKPPPPP------------------PPVGNRPSIHREAVPPPPPQN 289
Query: 549 EDPPKP--PKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILRE 606
PP P P+ S PP PP P P P P PP + TP LP++ S+
Sbjct: 290 NKPPVPSTPRPSASSQAPPP----PPPPSRPGPPPLPPSSSGNDETP-RLPQRNLSLSSS 344
Query: 607 -PTFRWTSLTRELPPPPPAPPPPPA----------PSPPPAPATSSRRPLLLRAPQFTPS 655
P + LPPPP PPPP P PPP S L PQ PS
Sbjct: 345 TPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQL-PS 403
Query: 656 EAHLKIYESVLTPP-PLGAPEAPEPEPPPA--------DDSPAEPE 692
+ + S PP P P A P PPP DSP E E
Sbjct: 404 RSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDE 449
Score = 85.5 bits (210), Expect = 6e-16
Identities = 130/519 (25%), Positives = 169/519 (32%), Gaps = 134/519 (25%)
Query: 1960 PPGPAPSPPPPEDLG----PDFEDMEVVSGLSA--ADLDFAASLLGT------EPFQEEI 2007
PP PAP PPP L P E +G +A +D+ L T P ++
Sbjct: 4 PPPPAPPPPPTFALANTEKPTLNKTEQ-AGRNALLSDISKGKKLKKTVTNDRSAPILDKP 62
Query: 2008 VAAGA------------MGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGA 2055
AGA G GG G S P PGL G
Sbjct: 63 KGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGP--------------PGLGGLFQAGM 108
Query: 2056 PRIEQLDGVDDGTDSEAEAVQQPRGQGT------PPSGPGVV-------RAGV------- 2095
P++ D+ + + P G+ T PPSGPG R+G
Sbjct: 109 PKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNR 168
Query: 2096 -------LGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQP 2148
+G+ D PP + N G P G GPR+ S P PP G++
Sbjct: 169 MPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPG-GPRQPSPGPTPPPFPGNRG 227
Query: 2149 SQ----GLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKM 2204
+ + SP + F+ P P +L P PP P +++
Sbjct: 228 TALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHR-------- 279
Query: 2205 AGEGEPVPPPVK-QPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPP----- 2258
E P PPP +PP+P T P+A + PP P RP PPP PP
Sbjct: 280 --EAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPP---------PSRPGPPPLPPSSSGN 328
Query: 2259 ------------------PLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRL 2300
PL SGP PP V GRS P PPP P +
Sbjct: 329 DETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPP---PPV 385
Query: 2301 DEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLP 2360
+G S P P L P+ GV D P +G P P S P
Sbjct: 386 SRNGSTSRALPATPQL------------PSRSGV---DSP--RSGPRPPLPPDRPSAGAP 428
Query: 2361 LPEDGPPQVPDGPPDLLLESQWHHYSGEASSSEEEPPSP 2399
P + +G D E +W S+ PP P
Sbjct: 429 PPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEP 467
Score = 83.2 bits (204), Expect = 3e-15
Identities = 79/275 (28%), Positives = 97/275 (35%), Gaps = 67/275 (24%)
Query: 404 PPLTPPAPS------PPPPLPPPSTSPP--PPLCPPPPPPVSPPPLPSPPPPPAQEEQEE 455
PPL PP PS PPPP PP P PPPPP + PP+PS P P A +
Sbjct: 250 PPL-PPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPP 308
Query: 456 SPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAP 515
PPP + G PPL PS E R P S ++ PP SP
Sbjct: 309 PPPP------PSRPGPPPLPPSSSGNDETPRL-------PQRNLSLSSSTPPLPSP---- 351
Query: 516 KSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQ 575
RS + P PP P +R P P
Sbjct: 352 ------------------GRSGPL------------PPPPSERPPPPVRDP-------PG 374
Query: 576 EPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPP 635
P+P PP ST LP + + P+ R P PP P P A +PPP
Sbjct: 375 RSGPLPPPPPVSRNGSTSRALP----ATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPP 430
Query: 636 APATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPP 670
P ++S R +P E+ + PPP
Sbjct: 431 PPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPP 465
Score = 76.6 bits (187), Expect = 3e-13
Identities = 82/317 (25%), Positives = 112/317 (35%), Gaps = 68/317 (21%)
Query: 470 GRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIM 529
G P L + + ++ G+ PP P + SP P +F +
Sbjct: 107 GMPKLRSTANRDNDSG-----GSRPPLLPPGGRSTSAKPFSPPSGPG---------RFPV 152
Query: 530 PVVSARSSRVIKTPRRFMDEDPPKPPKVEVSP-VLRPPITTSP-PVPQEP-----APVPS 582
P RS P + PP P V P + PP+ ++P P+ P PVP
Sbjct: 153 PSPGHRSG----PPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPG 208
Query: 583 PPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPS------PPPA 636
PR P+P TP P P R + L + R + L+ P PP PP PS PPP
Sbjct: 209 GPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSS-SPFSNRPPLPPTPSRALDDKPPPP 267
Query: 637 PATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPP-PADDSPAEPEPRA 695
P RP I+ + PPP + P P P P+ S A P P
Sbjct: 268 PPPVGNRP---------------SIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPP-- 310
Query: 696 VGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPP 755
P + P P S+G +L Q +L + P P
Sbjct: 311 ------------------PPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPG 352
Query: 756 PQPQLQPPPSPQQMPPL 772
L PPPS + PP+
Sbjct: 353 RSGPLPPPPSERPPPPV 369
Score = 68.2 bits (165), Expect = 1e-10
Identities = 98/379 (25%), Positives = 126/379 (33%), Gaps = 57/379 (15%)
Query: 1807 SPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPP--PAPRSFSGAR 1864
S P S P G P+ + G PE P +N PP RPD GS P P P +
Sbjct: 137 SAKPFSPPSGPGRFPVPSPGHRSGPPE---PQRNRMPPPRPDVGSKPDSIPPPVPSTPRP 193
Query: 1865 IKVPNYSPSRRPLGGVSFGPLPSPGSP-----------------SSLTHHIPTVGDPDFP 1907
I+ ++ P+ G P P P P S L+ P P P
Sbjct: 194 IQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLP 253
Query: 1908 APPRRSRRPSPLAPRPP----PS--RWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPP 1961
P R+ P P PP PS R A PP PQ PP S T S + PP
Sbjct: 254 PTPSRALDDKPPPPPPPVGNRPSIHREAVPP--PPPQNNKPPVPS--TPRPSASSQAPPP 309
Query: 1962 GPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPG 2021
P PS P P L P + L +L ++S T P + + G G P
Sbjct: 310 PPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSS---TPP----LPSPGRSGPLPPPPS 362
Query: 2022 DSSEEE-SSPTSRYIHF-PVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAV--QQ 2077
+ P R P VS G A P P++ GVD + +
Sbjct: 363 ERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDR 422
Query: 2078 PRGQGTPPSGPGV-VRAGVLGAAGD-------------RARPPEDLPSEIVDFVLKNLGG 2123
P PP P +R G + + PPE + K
Sbjct: 423 PSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLARN 482
Query: 2124 PGDGGAGPREESLPPAPPL 2142
G+ RE PP PP+
Sbjct: 483 ESRSGSNRRERGAPPLPPI 501
Score = 64.7 bits (156), Expect = 1e-09
Identities = 65/178 (36%), Positives = 70/178 (39%), Gaps = 25/178 (14%)
Query: 1801 NQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSF 1860
N+ +H A PP PP VP P R S PP P S PPP P S
Sbjct: 273 NRPSIHREAVPPPPPQNNKPP------VPSTP-RPSASSQAPPPPPPPSRPGPPPLPPSS 325
Query: 1861 SGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLA 1920
SG + P P R S PLPSPG L P PP RS PL
Sbjct: 326 SG-NDETPRL-PQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRS---GPLP 380
Query: 1921 PRPPPSR--WASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGP------APSPPPP 1970
P PP SR S L +PQL P S V +P SG P P AP PPPP
Sbjct: 381 PPPPVSRNGSTSRALPATPQL---PSRSGVD--SPRSGPRPPLPPDRPSAGAPPPPPP 433
Score = 58.9 bits (141), Expect = 7e-08
Identities = 126/513 (24%), Positives = 172/513 (33%), Gaps = 126/513 (24%)
Query: 23 RPRGAGGGGGRGGRGNGAERVRVALRRGGGATGPGGAEPGEDTALLRLLGL-RRGLRRLR 81
+P+GAG GGG GG G G GGG+ G GG PG L GL + G+ +LR
Sbjct: 61 KPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFG-GGGPPG-------LGGLFQAGMPKLR 112
Query: 82 RL--------WAGPRVQRGRGRGRGR-----GWGPSRGCVPEEESSDGESDEEEFQ---- 124
+ P + GR GP R VP G + + +
Sbjct: 113 STANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPP 172
Query: 125 --GFHSDEDVAPSSLRSALRSQRGRAPRGRGRKHKTTPLP-PPRLADVAPTPPKTPARKR 181
S D P + S R + +P RG + P+P PR PTPP P
Sbjct: 173 RPDVGSKPDSIPPPVPSTPRPIQS-SPHNRG----SPPVPGGPRQPSPGPTPPPFP---- 223
Query: 182 GEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVVA 241
G GT ++ + + +P + +R P TP R+ P P P + +
Sbjct: 224 GNRGTALGGGSIRQSPLSSSSPFS--NRPPLPPTPSRALDDKPPPPPPPVGNRPS---IH 278
Query: 242 EAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGGL 301
AV P P+ P VP + + P P P P G
Sbjct: 279 REAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRP-------------------GPP 319
Query: 302 PFVIKFVSRAKKVKMGQLSLGLESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQKL 361
P + ++ Q +L L S S +P G+ G L
Sbjct: 320 PLPPSSSGNDETPRLPQRNLSLSS---------STPPLP----SPGRSG---------PL 357
Query: 362 DDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPS--------- 412
E+ +D G R+ P + + P TP PS
Sbjct: 358 PPPPSERPPPPVRDPPG-----RSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRS 412
Query: 413 -PPPPLPP--PSTSPPPPLCPPPPPPV------SP-----------PPLPSPPPPPAQEE 452
P PPLPP PS PPP PPP + SP P+ PPP +
Sbjct: 413 GPRPPLPPDRPSAGAPPP--PPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQ 470
Query: 453 QEESPPPVVPATCS------RKRGRPPLTPSQR 479
+S P + S R+RG PPL P R
Sbjct: 471 TTKSYPSKLARNESRSGSNRRERGAPPLPPIPR 503
Score = 55.5 bits (132), Expect = 7e-07
Identities = 64/226 (28%), Positives = 80/226 (35%), Gaps = 51/226 (22%)
Query: 1788 PREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNL-----D 1842
P P H E Q + P P G P D + P P PIQ+
Sbjct: 151 PVPSPGHRSGPPEPQ---RNRMPPPRPDVGSKP----DSIPPPVPSTPRPIQSSPHNRGS 203
Query: 1843 PPL-----RPDSGSAPPPAP----RSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSS 1893
PP+ +P G PPP P + G I+ S S P PS
Sbjct: 204 PPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDK 263
Query: 1894 LTHHIPTVGD-PDF------PAPPRRSRRPSPLAPRP-----------PPSRWASPPLKT 1935
P VG+ P P PP+ ++ P P PRP PPSR PPL
Sbjct: 264 PPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPP 323
Query: 1936 SPQ-----LRVPPPTSVVTALTP------TSGELAPPGPAPSPPPP 1970
S R+P +++ TP SG L PP P+ PPPP
Sbjct: 324 SSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPP-PSERPPPP 368
Score = 32.7 bits (73), Expect = 5.0
Identities = 41/153 (26%), Positives = 51/153 (33%), Gaps = 7/153 (4%)
Query: 1035 SPEASPGPPGPRRGAGAGGPREEVVAHPGPEEQDSLLQRK-SARRCVKQRPSYDIFEDSD 1093
S +A P PP P R GP + G +E L QR S PS
Sbjct: 303 SSQAPPPPPPPSRP----GPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLP 358
Query: 1094 DSEPGGPPAPRRRTP-RENELPLPEPEEQSRPRKPTLQPVLQLKARRRLDKDALAPGPFA 1152
PP P R P R LP P P ++ L QL +R +D P P
Sbjct: 359 PPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPL 418
Query: 1153 SFPNGWTGKQKSPDGVHRVRVDFKEDCDLENVW 1185
G P +R F +D E+ W
Sbjct: 419 PPDRPSAGAPPPPPPSTSIRNGF-QDSPCEDEW 450
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 105 bits (263), Expect = 5e-22
Identities = 157/654 (24%), Positives = 223/654 (34%), Gaps = 139/654 (21%)
Query: 156 HKTTPLPPPRLADVAPTPPKTPARKR----------GEEGTERMVQALTELLRRAQAP-- 203
H+ P PPP P PP PA + + + + + LLRR P
Sbjct: 1035 HQAAPPPPP-----PPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQ 1089
Query: 204 ------------QAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPE 251
+A +A P+ R + R P + CR + + + P P
Sbjct: 1090 TPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSS-CRSRPALSPLGDIDFCPPNPG 1148
Query: 252 PPPPVVPVKHQTGSWKCKEGPGPGPGTPR--------RGGQSSR-----GGRGGRGRGRG 298
P P + T + + +GP G PR G +S G + RGRGRG
Sbjct: 1149 PDGPRRRGRKPTKAKR--DGPPRPRGRPRIRPLEVPTTAGPASASTPTDGAKKPRGRGRG 1206
Query: 299 GGLPFVIKFVSRAKKVKMGQLSLGLESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQE 358
G +R + +K ++ L VP+ G G +
Sbjct: 1207 RGRKAEEAGGTRLEPLKPLKIKLS----------------VPKAGEGLGTSSGDAISGTD 1250
Query: 359 QKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLP 418
D +++ E K KE EEK+ + M + ++ PPL A PP P
Sbjct: 1251 HNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQ-AGLTPPLSP 1309
Query: 419 PPSTSPPPPLCPPPPPPVSPPPLPSPPPPPA-------QEEQEESPPPVVPATCSR---- 467
P S P P P P + P +P PPP A + + E P+ C R
Sbjct: 1310 PKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDEE 1369
Query: 468 -KRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQ 526
KR L PS ++ E + A + +A +D P PK T+
Sbjct: 1370 LKRNLETL-PSFSSDEEDSVAKNRDLQESISSAISAL----DDPPLAGPKDTSTPDG--- 1421
Query: 527 FIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRA 586
P+ A + P PP + P T PP+ +E P P+PP A
Sbjct: 1422 --PPLAPAAAV--------------PGPPPLPGLPSANSNGTPEPPLLEEKPP-PTPPPA 1464
Query: 587 PTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPA--PSPPPAPATSSRRP 644
PTP P P P + L P + T PPPPP PPPPP PSPPP
Sbjct: 1465 PTPQPQPPPPPPPPQPALPSPP-PLVAPTPSSPPPPPLPPPPPPAMPSPPP--------- 1514
Query: 645 LLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPP--PADDSPAEPEPRAVGRTNHL 702
PPP AP A PE P P+ + P P+ R + HL
Sbjct: 1515 ----------------------PPPPAAAPLAAPPEEPAAPSPEDPELPDTRPL----HL 1548
Query: 703 SLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPP 756
+ + V E G + + + +L+ L PPP
Sbjct: 1549 AKKQETAAVCGETDEEAGESGGEGIFRERDEFVIRAEDIPSLKLALQTGREPPP 1602
Score = 84.0 bits (206), Expect = 2e-15
Identities = 104/371 (28%), Positives = 134/371 (36%), Gaps = 105/371 (28%)
Query: 392 PAAEKEEAKLPPPPLTP-PAPSPPPPLPPPSTSPPPPLCPP-----PPPPVSPPP---LP 442
P E++ PPP TP P P PPPP P P+ PPPL P PPPP+ PPP +P
Sbjct: 1451 PLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMP 1510
Query: 443 SPPPPPAQEEQEESPPPVVPATCSRKRGRPPLT-PSQRAER------------EAARAGP 489
SPPPPP + PP PA S + P T P A++ EA +G
Sbjct: 1511 SPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGETDEEAGESGG 1570
Query: 490 EGT------------SPPTPTPSTATGGPPED----SPTVAPKSTTFLKN-IRQFI---- 528
EG P+ + TG P + K T +K+ RQF
Sbjct: 1571 EGIFRERDEFVIRAEDIPSLKLALQTGREPPPIWRVQKALLQKFTPEIKDGQRQFCATSN 1630
Query: 529 -MPVVSARSSRVIKTPRRFMDEDPPKPPKVEV---SPVLRPPIT---------------T 569
+ +R + +F+ E+ K V V P RPP+ +
Sbjct: 1631 YLGYFGDAKNRYQRLYVKFL-ENVNKKDYVRVCARKPWHRPPVPVRRSGQAKNPVSAGGS 1689
Query: 570 SPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPP---PPPAPP 626
S P P+ PAP PP+ TP T T E PP P A P
Sbjct: 1690 SAPPPKAPAP---PPKPETPEKT----------------------TSEKPPEQTPETAMP 1724
Query: 627 PPPAPSPP-----------PAPATSSRRPL---LLRAPQFTPSEAHLKIYESVLTPPPLG 672
PPAP P T RPL + + T E L + + P
Sbjct: 1725 EPPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKA 1784
Query: 673 APEAPEPEPPP 683
P + EPPP
Sbjct: 1785 RPTKVKAEPPP 1795
Score = 82.8 bits (203), Expect = 4e-15
Identities = 235/1060 (22%), Positives = 327/1060 (30%), Gaps = 238/1060 (22%)
Query: 5 AGGGSCPGPGSARGRFPGR---PRGAGGGGGRGGRGNGAERVR---VALRRGGGATGPGG 58
AG S GP A GR P AGGGG GG G ++ +GG GG
Sbjct: 343 AGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGG 402
Query: 59 A---EPGEDTALLRLLGLRRGLRRLRRLWAGPRVQRGRGRGRGRGWGPSRGCVP-EEESS 114
A P TA + L GP G+ G G + P + +
Sbjct: 403 ATRPPPPRSTATPKCQSL-----------GGPAAAYATGKASGAGGAGGQAYSPGQPQGL 451
Query: 115 DGESDEEEFQGFHSDEDVAPSSLRSALRSQRGRAPRGRGRKHKTTPLPPPRLADV-APTP 173
G + G +D++ + S Q P PPP LA + +P
Sbjct: 452 LGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGP------------PPPGLATCQSYSP 499
Query: 174 PKTPARKRGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRR 233
+ + G +G A +P S P+ G P G
Sbjct: 500 DQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEA 559
Query: 234 KQQAVV--VAEAAVTIPKPEPPPPVVPVKHQT---GSWKCKEGPGPGPGTPRRGGQSSRG 288
++ + T P P P K+ + S PG G GG +G
Sbjct: 560 SPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKG 619
Query: 289 -------GRGGRGRGRGGGLPFVIKFVSRAKKVKMGQLSLGLESGQGQGQHEESWQDVPQ 341
G GG R F+I+ + +A + GL E+ D +
Sbjct: 620 DGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVG-------EDGAADASK 672
Query: 342 RRVGSGQGGSPCWKKQEQKLDDEEEE---------------------------KKEEEEK 374
GSG G P E +D + K++++
Sbjct: 673 GLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGP 732
Query: 375 DKEGEEKEERAVAEEMMPAAEKE-----EAKLPPPPLTPPAPSPPP-PLPPPSTSPPPPL 428
++ GE E A + A KE + PPPP T + P P L + P PL
Sbjct: 733 ERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPL 792
Query: 429 CPPPPPP----------VSPPP-----------------LPSPPPPPAQEEQEESPPPVV 461
PPPPP SP P P PPPPP PPP +
Sbjct: 793 VLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPP------PPPPPPM 846
Query: 462 PATCS---RKRGRPPLTPSQRAEREAARAGP-------EGTSPPTPTPSTATGGPPED-- 509
P R G P PS R E + P P P P GPP
Sbjct: 847 PLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEG 906
Query: 510 -SPTVAPKSTTFLKNIRQFIMPVVSA--RSSRVIKTPRRFM-------------DEDPPK 553
P A +S + +P+ S S + R F D
Sbjct: 907 KDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAG 966
Query: 554 PPKVEVSPVLRPPITTSPPVPQEPAPV---------PSPPRAPTPPSTPVPLPEKRRSIL 604
PP+ E P PP P P P P+ P LP ++
Sbjct: 967 PPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPS---TVN 1023
Query: 605 REPTFRWTSLTRE-LPPPPPAPPPPPAPSPPP-----APATSSRRP-----------LLL 647
EP S + PPPPP PPPPPAP+ P +P S +P L
Sbjct: 1024 AEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRR 1083
Query: 648 RAPQF-TPSEAHLKIYE-------------------------------SVLTP------- 668
R P F TP + + + YE L+P
Sbjct: 1084 RDPPFQTPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSPLGDIDFC 1143
Query: 669 PPLGAPEAP--EPEPPPADDSPAEPEPRAVGRTNHLSLPRFA--PVVTTPVKAEVSPHGA 724
PP P+ P P P PR R L +P A +TP P G
Sbjct: 1144 PPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPTDGAKKPRGR 1203
Query: 725 PALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGV--GS 782
G +A+ +A T+L P L P + +L P + + + I+G S
Sbjct: 1204 ---GRGRGRKAE-----EAGGTRLEP--LKPLKIKLSVPKAGEGLGTSSGDAISGTDHNS 1253
Query: 783 LPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISDRGPV 842
L S EK+ + +K + K + + +A+ + G+ P
Sbjct: 1254 LDSSLTREKIEAKIKEVEE---KQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPP 1310
Query: 843 RSEDESVEAKRERPSGPESPVQGPRIKHVCRHAAVALGQA 882
+S SV A+ +P P +P + H A LG A
Sbjct: 1311 KSVPPSVPARGLQPQPPATPA----VPHPPPSGAFGLGGA 1346
Score = 74.3 bits (181), Expect = 1e-12
Identities = 159/688 (23%), Positives = 232/688 (33%), Gaps = 136/688 (19%)
Query: 551 PPKPPKVEVSPVLRPPITTSP-----------PVPQEPAPVPSPPRAPTPPSTPV----- 594
PP PP++ S + P + SP P ++ AP P PP P PP P+
Sbjct: 795 PPPPPQLLPSVLSHAP-SPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAH 853
Query: 595 ----------PLPEKRRSILREPTFRWTSLTRELPPPPPAPP-----PPPAPSPPPAPAT 639
P P R +P L L P PPAP PP + PA A
Sbjct: 854 LRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAY 913
Query: 640 SSRRPLLLRAPQFTP------SEAHLKIYESVLTPPPL-----GAPEAPEPEPPPADDSP 688
S P +AP+F P ++ L+ E P GA + PP D
Sbjct: 914 RSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPED--- 970
Query: 689 AEPEPRAVGRTNHLSLPRFAPVVT-TPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQ 747
E +P+A G P + P P +A + P L P +L + A
Sbjct: 971 -EGDPKA-GAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLG 1028
Query: 748 LLP----QALPPPQPQLQPPPSPQQMPPLEKARIAGVGSLPLSGVEEKMFSLLKR----- 798
L+ QA PPP P PPP+P P + P ++ F LL+R
Sbjct: 1029 LIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPF 1088
Query: 799 -------AKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAG-----AVKQISD-------- 838
A+ F+ D+ + V A + L+P + V+ A+ + D
Sbjct: 1089 QTPKKLYAQEYEFEADEDKAD-VPADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNP 1147
Query: 839 --RGPVRSEDESVEAKRERPSGPESPVQGPRIKHVCRHAAVALGQARAMVPEDVPRLSAL 896
GP R + +AKR+ GP P PRI+ + G A A P D A
Sbjct: 1148 GPDGPRRRGRKPTKAKRD---GPPRPRGRPRIRPL--EVPTTAGPASASTPTD----GAK 1198
Query: 897 PLRDRQDLATEDTSSASETESVPSRSRRGKVEAAGPGGESEPTGSGGTLAHTPRRSLPSH 956
R R A T P + + K+ + GE T SG ++ T SL S
Sbjct: 1199 KPRGRGRGRGRKAEEAGGTRLEPLKPLKIKL-SVPKAGEGLGTSSGDAISGTDHNSLDSS 1257
Query: 957 HGKKMRMARCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQCCVYRKCDKIEARKMERL 1016
++ A+ G + LD K G K+ +Y+ +
Sbjct: 1258 LTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSG----KRHPPLYQ-------AGLTPP 1306
Query: 1017 AKKGRTIVKTLLPWDSDESPEASPGPPGP----------------RRGAGAGGPRE---- 1056
+++ ++ P A+P P P G G G P
Sbjct: 1307 LSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRL 1366
Query: 1057 --------EVVAHPGPEEQDSLLQRKSARRCVKQRPSY----DIFEDSDDSEPGGPP-AP 1103
E + +E+DS+ + + + + S + D S P GPP AP
Sbjct: 1367 DEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAP 1426
Query: 1104 RRRTPRENELP-LPEPEEQSRPRKPTLQ 1130
P LP LP P P L+
Sbjct: 1427 AAAVPGPPPLPGLPSANSNGTPEPPLLE 1454
Score = 72.4 bits (176), Expect = 6e-12
Identities = 158/638 (24%), Positives = 210/638 (32%), Gaps = 100/638 (15%)
Query: 1808 PAPSSEPPGGEDPPLDTDVLVPGAPERHS--PIQNLDPPLRP-------------DSGSA 1852
PAP+SEP GG P+ + S ++ DPP + D A
Sbjct: 1049 PAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKA 1108
Query: 1853 PPPAPRSFSGAR----IKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTH-HIPTVGDPDFP 1907
PA + R + P+ PLG + F P P+PG PT D P
Sbjct: 1109 DVPADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCP-PNPGPDGPRRRGRKPTKAKRDGP 1167
Query: 1908 APPRRSRRPSPL-APRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPS 1966
PR R PL P AS P + + R A L P P
Sbjct: 1168 PRPRGRPRIRPLEVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAGGTRLEPLKPLKI 1227
Query: 1967 ----PPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEI------VAAGAMGS- 2015
P E LG D +SG LD + + E +E+ + +G M S
Sbjct: 1228 KLSVPKAGEGLGTSSGD--AISGTDHNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASF 1285
Query: 2016 ------SHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPS--ATPGAPRIEQLDGVDDG 2067
P + P S P +V A GL P ATP P G
Sbjct: 1286 LDFLKSGKRHPPLYQAGLTPPLSPPKSVPPSV-PARGLQPQPPATPAVPHPPPSGAFGLG 1344
Query: 2068 TDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPS---EIVDFVLKN---- 2120
EA A + G G P + + R E LPS + D V KN
Sbjct: 1345 GALEA-AESEGLGLGCPSPCKRLDE--------ELKRNLETLPSFSSDEEDSVAKNRDLQ 1395
Query: 2121 ------LGGPGDGG-AGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVR 2173
+ D AGP++ S P PPLA P+ + P P A G P
Sbjct: 1396 ESISSAISALDDPPLAGPKDTSTPDGPPLA----PAAAVPGPPPLPGLPSANSNGTPEPP 1451
Query: 2174 VLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWT 2233
+L P P PP T + P PPP QP LP APT +
Sbjct: 1452 LLEEKPPPTPPPAPTPQ----------------PQPPPPPPPPQPALPSPPPLVAPTPSS 1495
Query: 2234 LPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPP 2293
PP PL P P+PPPPPPP L++ P P S P P
Sbjct: 1496 PPPPPLP---PPPPPAMPSPPPPPPPAAAPLAAPPEEPAAP-------SPEDPELPDTRP 1545
Query: 2294 PYKAPRLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQ 2353
+ A + + E + G G R R + + + G E P +
Sbjct: 1546 LHLAKKQETAAVCGETDEEAGESGGEGIFRERDEFVIRAEDIPSLKLALQTGREPPPIWR 1605
Query: 2354 ERSPLLPLPEDGPPQVPDGPPDLLLESQWHHYSGEASS 2391
+ LL + P++ DG S + Y G+A +
Sbjct: 1606 VQKALL---QKFTPEIKDGQRQFCATSNYLGYFGDAKN 1640
Score = 61.6 bits (148), Expect = 1e-08
Identities = 130/547 (23%), Positives = 178/547 (32%), Gaps = 123/547 (22%)
Query: 1847 PDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIP-----TV 1901
P+ G P G V +Y + LG P P + T P
Sbjct: 732 PERGGETP------EGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEA 785
Query: 1902 GDPDFPA---PPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGEL 1958
G PD P PP PS L+ P PS AS K L L P + +
Sbjct: 786 GGPDLPLVLPPPPPQLLPSVLSHAPSPSPSAS---KVGVHL-----------LEPATRDG 831
Query: 1959 APPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHG 2018
AP P P PPPP + +++ + L + L+ AA P +E + GAM G
Sbjct: 832 APQPPPPPPPPPPPM-----PLQLEAHLRSHGLEPAAPSPRLRP-EESLDPPGAMQELLG 885
Query: 2019 -------GPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSE 2071
PGD+ P + P +P +P T APR L +
Sbjct: 886 ALEPLPPAPGDTG---VGPPNSEGKDPAGAYRSP--SPQGTK-APRFVPLTSI-----CF 934
Query: 2072 AEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGP 2131
+++ Q + P+ + G G +A PPED G GAGP
Sbjct: 935 PDSLLQDEERSFFPTMEEMFGGGAADDYG-KAGPPED-------------EGDPKAGAGP 980
Query: 2132 REESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKI 2191
PP PP + P P R P PG L L P P P+T
Sbjct: 981 -----PPGPPAYD--------PYGPYCPGRASGAGPETPG---LGLDPNKPPELPST--- 1021
Query: 2192 ILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRP 2251
+ LG + +G + PPP PP PP P
Sbjct: 1022 VNAEPLGLI---QSGPHQAAPPPPPPPPPPPA---------------------------P 1051
Query: 2252 APPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTP 2311
A P + + S + P++ ++ R PP P K + + EA ED
Sbjct: 1052 ASEPKGGLTSPIFCS---TKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKA 1108
Query: 2312 QVPGLGSGGFSRVRMKTPTVRGVLDLDRPGE----PAGEESPGPLQERSPLLPLPEDGPP 2367
VP R+ + R L G+ P GP + DGPP
Sbjct: 1109 DVPADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNPGPDGPRRRGRKPTKAKRDGPP 1168
Query: 2368 QVPDGPP 2374
+ P G P
Sbjct: 1169 R-PRGRP 1174
Score = 58.5 bits (140), Expect = 9e-08
Identities = 130/567 (22%), Positives = 185/567 (32%), Gaps = 105/567 (18%)
Query: 1815 PGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSR 1874
P G DT + G+ + + NL L G P P+ S ++ + P++ +
Sbjct: 65 PAGLSGLFDTGLHHAGSAGPDASVMNLISALE-SRGPQPGPSASSLL-SQFRSPSWQTAM 122
Query: 1875 RPLGGVSF---GPLPSPGS-PSSLT----HHIPTVGDPDFPAPPRRSRRPSPLAPRPPPS 1926
G G LP + PSS H + G FP P S + P +P P +
Sbjct: 123 HTPGPTELFISGALPGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSP--PAN 180
Query: 1927 RWASPP--LKTSPQLRVPPPTSVVTALTPTSGELAP------------PGPAPSPPPPED 1972
SP L P P+S+ G L P PGP PPPP
Sbjct: 181 GLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRH 240
Query: 1973 LGPDFEDMEVVSGLSAAD-------LDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSE 2025
L F + S +AA +F+ + G P + + + + P +
Sbjct: 241 LPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQP 300
Query: 2026 EESSPTSRYI-HFPVTVVSAPGLA--------------PSATPGAPRIEQLDGVDDGTDS 2070
P + + H+ S P + PS G P G G
Sbjct: 301 PPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGPSGATAGASG 360
Query: 2071 EAEAVQQPRGQGTPPSGPG-----------VVRAGVLGAAGDRARPPEDLPSEIVDFVLK 2119
A + G G G G + G AAG RPP P +
Sbjct: 361 RATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPP--PRSTATPKCQ 418
Query: 2120 NLGGP----------GDGGAGPREESLPPAPPLANGSQPSQGLTASPA-DPTRTFAWLPG 2168
+LGGP G GGAG + S L QG A D ++ ++ G
Sbjct: 419 SLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGG 478
Query: 2169 APGVRVLSLGPAPEPPKPATSKIILVNKL-GQVFVKMAGEGEPVPPPVKQPPLPPTISPT 2227
P P PP AT + ++L GQ++ +GEP P P PT SP+
Sbjct: 479 PP-----QPPSGPPPPGLATCQSYSPDQLQGQLY---GVQGEPYPGPAAHSQGLPTASPS 530
Query: 2228 APTSWTLPP---------GPLL----GVLPVVGVVRPAPPPP----PPPLTLVLSSGPAS 2270
S P GP G ++RP PP PP + P +
Sbjct: 531 LSYSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPGV-----GSPGA 585
Query: 2271 PPRQAIRVKRVSTFSGRSPPAPPPYKA 2297
P + V + F +PP Y A
Sbjct: 586 PGKYLSSVLASAPF--LAPPGAGSYAA 610
Score = 57.0 bits (136), Expect = 2e-07
Identities = 99/438 (22%), Positives = 154/438 (35%), Gaps = 75/438 (17%)
Query: 118 SDEEEFQGFHSDEDVAPSSLRSALRSQRGRAPRGRGRKHKTTPLPPPRL-ADVAPTPPKT 176
SDEE+ + D + SS SAL P G K +TP PP A P PP
Sbjct: 1382 SDEEDSVAKNRDLQESISSAISALDD-----PPLAGPKDTSTPDGPPLAPAAAVPGPPPL 1436
Query: 177 PAR-KRGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQ 235
P GT LL P P + +P P PP P P
Sbjct: 1437 PGLPSANSNGTPE-----PPLLEEKPPPTPPPAPTPQPQPP------PPPPPPQPALPSP 1485
Query: 236 QAVVVAEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGR 295
+V + P P PPPP + P P P ++
Sbjct: 1486 PPLVAPTPSSPPPPPLPPPPPPAMPSP-----------PPPPPPAAAPLAAPPEEPAAPS 1534
Query: 296 GRGGGLPFVIKFVSRAKKVKMGQL------SLGLESGQGQGQHEESW----QDVPQRRVG 345
LP + + AKK + + G G+G + + + +D+P ++
Sbjct: 1535 PEDPELPDT-RPLHLAKKQETAAVCGETDEEAGESGGEGIFRERDEFVIRAEDIPSLKLA 1593
Query: 346 --SGQGGSPCWKKQEQKLDDEEEEKKEEEEKD----------KEGEEKEERAVAEEMMPA 393
+G+ P W+ Q+ L E K+ + + + + + +R + +
Sbjct: 1594 LQTGREPPPIWRVQKALLQKFTPEIKDGQRQFCATSNYLGYFGDAKNRYQRLYVKFLENV 1653
Query: 394 AEKEEAKL--------PPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPP 445
+K+ ++ PP P+ + P S++PPP PPP P +P S
Sbjct: 1654 NKKDYVRVCARKPWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEK 1713
Query: 446 PPPAQEE--QEESPPPVVPA---TCSRKRGRPPLTPSQRAER-EAARAGPEGTSPPTPTP 499
PP E E P P P+ +++ + +T +R R E A +G + P
Sbjct: 1714 PPEQTPETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQ----TRPER 1769
Query: 500 STATGGP-----PEDSPT 512
S ATG P P+ PT
Sbjct: 1770 SLATGQPATSRLPKARPT 1787
Score = 53.5 bits (127), Expect = 3e-06
Identities = 139/650 (21%), Positives = 210/650 (32%), Gaps = 109/650 (16%)
Query: 1802 QTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAP--PPAPRS 1859
QT + P P PP P ++L + + Q+ P L SG+AP PP R+
Sbjct: 223 QTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQS-SPQLYNFSGAAPGPPPPERA 281
Query: 1860 FSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPL 1919
+ +Y +RP S P P P +L H++ G +P+ R+
Sbjct: 282 LPRQDTVIKHY---QRP---ASAQPPPPPPPAHALQHYLSCGGS--YPSMGHRANLACSP 333
Query: 1920 APRPPPSRWASPPLKTSPQLRVPPPTSVVTA-------------------------LTPT 1954
PS A P K P + T T
Sbjct: 334 LGGGEPSPGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGK 393
Query: 1955 SGELAPPGPAPSPPPPEDLG-PDFEDMEVVSGLSAADLDFAASLLGTEPFQ----EEIVA 2009
G A G A PPPP P + + + A A G + + + ++
Sbjct: 394 GGYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLG 453
Query: 2010 AGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTD 2069
A G GG G + + +P+ Y P S P AT + +QL G G
Sbjct: 454 PQAYGQGFGG-GQAQDLSKAPS--YSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQ 510
Query: 2070 SEAEAVQQPRGQGTPPSGPGVVRA----------------GVLGAAGDRA-----RPPED 2108
E QG P + P + + LG G+ + RP +
Sbjct: 511 GEPYPGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIRPLQS 570
Query: 2109 LPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPG 2168
P+ + + G PG + + APP A G D + A G
Sbjct: 571 PPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGPGG 630
Query: 2169 APGVR-------VLSLGPAPEPPKPATSK-IILVNKLGQVFVKMAGEGEPVPPP------ 2214
P R + L AP PP+ + + ++ + + G G PP
Sbjct: 631 PPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAADASKGLGGSGGAGGPPGTPYEL 690
Query: 2215 VKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQ 2274
K+ P + TS +L G + +G ++ P G +P
Sbjct: 691 AKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGP--------ERGGETPEGL 742
Query: 2275 AIRV-------KRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRVRMK 2327
A V K + F +SPP PPP ++++ TP L +GG +
Sbjct: 743 ATSVVHYGAGAKELGAFLQKSPPPPPP--------TAQSTQPTPHGLLLEAGGPDLPLVL 794
Query: 2328 TPTVRGVLDLDRPGEPAGEESPGPLQERSP---LLPLPEDGPPQVPDGPP 2374
P +L P + SP P + L P DG PQ P PP
Sbjct: 795 PPPPPQLL----PSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPP 840
Score = 41.2 bits (95), Expect = 0.014
Identities = 34/96 (35%), Positives = 45/96 (46%), Gaps = 14/96 (14%)
Query: 2220 LPPTISPTAPTSWTLPPGPLLGVLPVVGV-------VRPAPP-PPPPPLTL-----VLSS 2266
L P+ +PT P+S GVL G+ RP PP PPPPP L +L+S
Sbjct: 191 LKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLAS 250
Query: 2267 GPASPPRQAIRVKRVSTFSGRSPPAPPPYKA-PRLD 2301
A+ ++ FSG +P PPP +A PR D
Sbjct: 251 SSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQD 286
Score = 40.0 bits (92), Expect = 0.031
Identities = 43/147 (29%), Positives = 59/147 (40%), Gaps = 43/147 (29%)
Query: 626 PPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPAD 685
PPP AP+PPP P T P+ T SE PP PE PEPP
Sbjct: 1692 PPPKAPAPPPKPET----------PEKTTSE-----------KPPEQTPETAMPEPP--- 1727
Query: 686 DSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVS----PHGAPALSNGPQTQAQLLQPL 741
+P +P SL R PV K +V+ P ++G QT+ +
Sbjct: 1728 -APEKP-----------SLLR--PVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLAT 1773
Query: 742 QALQTQLLPQALPPPQPQLQPPPSPQQ 768
T LP+A P + + +PPP ++
Sbjct: 1774 GQPATSRLPKA-RPTKVKAEPPPKKRK 1799
Score = 38.5 bits (88), Expect = 0.091
Identities = 42/146 (28%), Positives = 52/146 (35%), Gaps = 40/146 (27%)
Query: 595 PLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTP 654
P+P +R + P S PPP AP PPP P P T+S +P P+ TP
Sbjct: 1671 PVPVRRSGQAKNPV----SAGGSSAPPPKAPAPPPKPETP--EKTTSEKP-----PEQTP 1719
Query: 655 SEAHLKIYESVLTPPPLGAPEAP----------EPEPPPADDSPAEPEPRAVGR------ 698
E+ + PP APE P E E + P E GR
Sbjct: 1720 --------ETAMPEPP--APEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPER 1769
Query: 699 ---TNHLSLPRFAPVVTTPVKAEVSP 721
T + R T VKAE P
Sbjct: 1770 SLATGQPATSRLPKARPTKVKAEPPP 1795
Score = 38.1 bits (87), Expect = 0.12
Identities = 58/225 (25%), Positives = 78/225 (34%), Gaps = 34/225 (15%)
Query: 481 EREAARAGPEGTS------PPTPTPSTATGGPPEDSPTVA-PKSTTFLKNIRQFIMPVVS 533
E + GP +S P+ + T GP E + A P S+TF + +
Sbjct: 96 ESRGPQPGPSASSLLSQFRSPSWQTAMHTPGPTELFISGALPGSSTFPSSSALSAYQHPA 155
Query: 534 ARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTP 593
+ SR P +DPP P + +L P P +APT PS+
Sbjct: 156 SFGSRPFPVPSSLSLQDPPFSPPA--NGLLSPHDVLHL----------KPSQAPTVPSS- 202
Query: 594 VPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPP----------APSPPPAPATSSRR 643
+ + P + T P PP PPPPP A S A A
Sbjct: 203 LGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSS 262
Query: 644 PLLLR----APQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPA 684
P L AP P E L ++V+ A P P PPPA
Sbjct: 263 PQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPA 307
Score = 36.2 bits (82), Expect = 0.45
Identities = 39/148 (26%), Positives = 49/148 (33%), Gaps = 45/148 (30%)
Query: 401 LPPPPLTPPA-------------PSPPPPLPPP---------STSPPPPLCPPPPPPVSP 438
L PP +PPA PS P +P P L P PP P
Sbjct: 170 LQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRP 229
Query: 439 PPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPT 498
P P PPPPP P + A AA A E +SP
Sbjct: 230 GP-PDPPPPPRHL---------------------PTQFNLLASSSAAAAAAEQSSPQLYN 267
Query: 499 PSTATGGPPEDSPTVAPKSTTFLKNIRQ 526
S A GPP + P+ T +K+ ++
Sbjct: 268 FSGAAPGPPPPERAL-PRQDTVIKHYQR 294
Score = 34.3 bits (77), Expect = 1.7
Identities = 45/177 (25%), Positives = 59/177 (33%), Gaps = 44/177 (24%)
Query: 161 LPPPRLADVAPTPPKTPARKRGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPR--R 218
L P + P PP P R + LL + A A A E S+P+
Sbjct: 219 LGPAQTPPYRPGPPDPPP-------PPRHLPTQFNLLASSSAAAA----AAEQSSPQLYN 267
Query: 219 SRGRPPGRPAGPCRRKQQAVVVA--EAAVTIPKPEPPPPVVPVKHQT---GSW------- 266
G PG P +Q V+ + + P PPPP ++H GS+
Sbjct: 268 FSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRA 327
Query: 267 --KCKE----GPGPGPGTPRRGGQS-------------SRGGRGGRGRGRGGGLPFV 304
C P PG G P + G S G GG G G GG P +
Sbjct: 328 NLACSPLGGGEPSPGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPII 384
Score = 33.1 bits (74), Expect = 3.8
Identities = 40/151 (26%), Positives = 43/151 (28%), Gaps = 49/151 (32%)
Query: 404 PPLTPP-APSPPPPLPPPSTSP-------------------PPPL------CPPPPPPVS 437
P TPP P PP P PPP P P L P PPPP
Sbjct: 221 PAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPER 280
Query: 438 PPP---------------LPSPPPPPAQEEQE-----ESPPPV---VPATCSRKRGRPPL 474
P P PPPPPA Q S P + CS G P
Sbjct: 281 ALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPS 340
Query: 475 TPSQRAEREAARAGPEGTSPPTPTPSTATGG 505
+ + G S P A GG
Sbjct: 341 PGAGEPSKAGPSGATAGASGRATGPEAAGGG 371
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 105 bits (262), Expect = 6e-22
Identities = 131/513 (25%), Positives = 172/513 (33%), Gaps = 81/513 (15%)
Query: 392 PAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSP--PPLPSPP---- 445
PA P P A PPP P P PP P P P P+PP
Sbjct: 67 PAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKL 126
Query: 446 -PPPAQEEQEESPPPVVPATCSRKRGRP--PLTPSQRAEREAARAGPEGTSPPTPTPSTA 502
PPP +P P A + P P P+ A AARAGP P P P
Sbjct: 127 RPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAAL-AARAGPGPGPGPGPGPGPG 185
Query: 503 TGGPPEDSPTVAPKSTTFLKNIRQFIMPVVS---------------ARSSRVIKTPRRFM 547
G P + L N P VS A VI+TP
Sbjct: 186 PGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVG 245
Query: 548 DEDPPKP--PKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILR 605
PP P P +P P PP P PA + PP P P T P ++
Sbjct: 246 AAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAP------AVPP 299
Query: 606 EPTFRWTSLTRELPPPPPA---------PPPPPAPSPPPAPATSSRRPLLLRAPQFTPSE 656
+ P P PA P P A + PAP + P R Q P
Sbjct: 300 PAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESP--KRVVQAAPPA 357
Query: 657 AHL--------KIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFA 708
A V+ P GA +P PPPA +P A G SL R
Sbjct: 358 AQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQ-SLSRTP 416
Query: 709 PVVTTPVKAEVSPHG-APALSNGPQT-------------------QAQLLQPLQALQTQL 748
T+ ++A ++P AP L PQ QLL Q Q+
Sbjct: 417 TATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQM 476
Query: 749 LPQALPPPQPQLQP-PPSPQQMPPLEKARIAGVGSLPLSGVEEKMFSLLKRAKVQLFKID 807
QA PQ + P P +P PP++ + + G+ P+ + +++K+
Sbjct: 477 QAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPGT-PIIARQVTPTTIIKQVS------Q 529
Query: 808 QQQQQKVAASMPLSPGGQMEEVAGAVKQISDRG 840
Q + +A++ SPG Q + V G Q + G
Sbjct: 530 AQTTVQPSATLQRSPGVQPQLVLGGAAQTASLG 562
Score = 89.0 bits (219), Expect = 6e-17
Identities = 171/730 (23%), Positives = 230/730 (31%), Gaps = 160/730 (21%)
Query: 169 VAPTPPKTPARKRGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPRRSRGRP----P 224
+AP P+ A G G + + A A + P P R RP P
Sbjct: 43 LAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGP 102
Query: 225 GRPAGPCRRKQQAVVVAEAAVTIPKPEPPPP-----VVPVKHQTGSWKCKEGPGPGPGTP 279
RP P R+ +V A A K PPP PV GP P P P
Sbjct: 103 QRPGPPSPRRP--LVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAA---VAAGPEPAPAGP 157
Query: 280 RRGGQSSRGGRGGRGRGRGGGLPFVIKFVSRAKKVKMGQLSLGLESGQGQGQHEESWQDV 339
+ G +L +G G G
Sbjct: 158 AKPA---------------------------------GPAALAARAGPGPG--------- 175
Query: 340 PQRRVGSGQG-GSPCWKKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEE 398
P G G G G P Q L+ A +P
Sbjct: 176 PGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPG 235
Query: 399 AKLPPPPLTPPA--PSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEES 456
+ PP A P+P P PP + +P P PPPPP +P L PP PA
Sbjct: 236 TVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPA------G 289
Query: 457 PPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPK 516
PP PA PP +Q G++ P P+ A GGP S P
Sbjct: 290 PPTAAPAV-------PPPAAAQNG----------GSAGAAPAPAPAAGGPAGVSGQPGPG 332
Query: 517 STTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPV--P 574
+ P V A S P+R + PP + S P T + V P
Sbjct: 333 AAAAAP------APGVKAES------PKRVVQAAPPAAQTLAAS---GPASTAASMVIGP 377
Query: 575 QEPAPVPSPPRAPTP-PSTPVPLPE-----KRRSILREPTFRWTSLTRELPP---PPPAP 625
+PSP P P P TP LP+ +S+ R PT + + L P P P
Sbjct: 378 TMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLP 437
Query: 626 PPPPAPS-------PPPAPATSSRRPLLLRAPQFTPSEAHLKIY---ESVLTPPPLGAPE 675
PP P+ PP S LL PQ ++ + + ++ + P P
Sbjct: 438 QPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTS 497
Query: 676 APEPEPPPADDSPAEP-EPRAVGRTNHLSLPRFAPVVTTP-VKAEVSPHGAPALSNGPQT 733
AP P +P P R V T + A P + SP P L G
Sbjct: 498 AP-PVQISTVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAA 556
Query: 734 QAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGVGSLPLSGVEEKMF 793
Q L A+QT +PQ+ P G+ S +
Sbjct: 557 QTASLGTATAVQT-----------------GTPQRTVP---------GATTTSSAATETM 590
Query: 794 SLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISDR---GPVRSEDESVE 850
+K+ K L + K+A+S G Q E A VK++ G + +ED +
Sbjct: 591 ENVKKCKNFLSTL-----IKLASS-----GKQSTETAANVKELVQNLLDGKIEAEDFTSR 640
Query: 851 AKRERPSGPE 860
RE S P+
Sbjct: 641 LYRELNSSPQ 650
Score = 79.3 bits (194), Expect = 5e-14
Identities = 113/469 (24%), Positives = 159/469 (33%), Gaps = 95/469 (20%)
Query: 1854 PPAPRSFSGARIKVPNYSPSRRPLGGVSFGPL-PSPGSPSSLTHHIPTV------GDPDF 1906
P P + A + N+ S P G GP P+ G+P + P G P
Sbjct: 45 PRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQR 104
Query: 1907 PAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPT---SGELAPPGP 1963
P PP R P P PP ++ PP + S P P + A P +G P GP
Sbjct: 105 PGPPSPRRPLVPAGPAPPAAKLRPPP-EGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGP 163
Query: 1964 A-------PSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSS 2016
A P P P GP + +A L+ +A+LL + AA A+
Sbjct: 164 AALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHH-----AAAPAVSLV 218
Query: 2017 HGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQ 2076
+ GP + P + P TV+ P +A P AP
Sbjct: 219 NNGPA-ALLPLPKPAA-----PGTVIQTPPFVGAAAPPAPAAP----------------- 255
Query: 2077 QPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESL 2136
+PP+ P A A PP P+ L P AGP +
Sbjct: 256 ------SPPAAPA--------PAAPAAAPPPPPPAPAT------LARPPGHPAGPPTAAP 295
Query: 2137 PPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNK 2196
PP A + S G +PA A + G PG + PAP + +++
Sbjct: 296 AVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQA-- 353
Query: 2197 LGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAP--TSWTLPPGPLL-GVLPVVGVVRPAP 2253
PP T++ + P T+ ++ GP + G LP V
Sbjct: 354 --------------------APPAAQTLAASGPASTAASMVIGPTMQGALPSPAAV---- 389
Query: 2254 PPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDE 2302
PPP P L G A Q++ +T SG P APRL +
Sbjct: 390 PPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQ 438
Score = 72.8 bits (177), Expect = 4e-12
Identities = 91/358 (25%), Positives = 119/358 (33%), Gaps = 40/358 (11%)
Query: 2050 SATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPED- 2108
+A GA + G G A G P P RA G R PP
Sbjct: 52 AAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPR 111
Query: 2109 ---LPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAW 2165
+P+ K L P +G AG +P A +A G +P+ A PA P A
Sbjct: 112 RPLVPAGPAPPAAK-LRPPPEGSAGSCAP-VPAAAAVAAGPEPAPAGPAKPAGPAALAAR 169
Query: 2166 LPGAPGVRVLSLGPAPEPPKPA----------TSKIILVNKLGQVFVKMAGEGE----PV 2211
PG GP P P KPA ++ ++ + V + G P+
Sbjct: 170 AGPGPGPGP-GPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPL 228
Query: 2212 PPP------VKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLS 2265
P P ++ PP +P AP + P P P P PPPP P
Sbjct: 229 PKPAAPGTVIQTPPFVGAAAPPAPAA----PSPPAAPAPAAPAAAPPPPPPAPATLARPP 284
Query: 2266 SGPASPPRQAIRVKRVSTF----SGRSPPAPPPY---KAPRLDEDGEASEDTPQVPGLGS 2318
PA PP A V + S + PAP P A + G + PG+ +
Sbjct: 285 GHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKA 344
Query: 2319 GGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLPLPEDGPPQVPDGPPDL 2376
RV P L P A GP + + LP P PP P P L
Sbjct: 345 ESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGA--LPSPAAVPPPAPGTPTGL 400
Score = 63.5 bits (153), Expect = 3e-09
Identities = 116/505 (22%), Positives = 165/505 (32%), Gaps = 97/505 (19%)
Query: 1785 PWGPREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPP 1844
P GP A L E +P P++ P P P + P
Sbjct: 116 PAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPG 175
Query: 1845 LRPDSGSAPPP-------APRSFSGARIKVPNYSPSRRPLGGVSFGP-----LPSPGSPS 1892
P G P P A ++ +G+ + ++ + + V+ GP LP P +P
Sbjct: 176 PGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPG 235
Query: 1893 SLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALT 1952
++ P VG PAP PSP A P + A+PP PPP + T
Sbjct: 236 TVIQTPPFVGAAAPPAPAA----PSPPAAPAPAAPAAAPP---------PPPPAPATLAR 282
Query: 1953 PTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGA 2012
P PP AP+ PPP +G SA AA A
Sbjct: 283 PPGHPAGPPTAAPAVPPP---------AAAQNGGSAG-------------------AAPA 314
Query: 2013 MGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEA 2072
+ GGP S + + P +P A P A + G + A
Sbjct: 315 PAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASG---PASTAA 371
Query: 2073 EAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPR 2132
V P QG PS P V G P LP G AG
Sbjct: 372 SMVIGPTMQGALPS-PAAVPPPAPGT-------PTGLPK---------------GAAGAV 408
Query: 2133 EESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAP----GVRVLSLGPAPEPPKPAT 2188
+SL P + + G+ A+ PT LP P ++ L P +
Sbjct: 409 TQSLSRTP-----TATTSGIRAT-LTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSEN 462
Query: 2189 SKIILVNKLGQVFVKMAGEGEPVPPPVKQP-PLPPTISPTAPTSWTLPPG-PLLG--VLP 2244
+++++ + Q +M + P P P PT +P S PG P++ V P
Sbjct: 463 GQLLMIPQ--QALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPGTPIIARQVTP 520
Query: 2245 --VVGVVRPAPPPPPPPLTLVLSSG 2267
++ V A P TL S G
Sbjct: 521 TTIIKQVSQAQTTVQPSATLQRSPG 545
Score = 49.3 bits (116), Expect = 5e-05
Identities = 170/804 (21%), Positives = 241/804 (29%), Gaps = 154/804 (19%)
Query: 3 AAAGGGSCPGPGSARGRFPGRPRGAGGGGGR------GGRGNGAERVRVALRRGGGATGP 56
A GGG PG R P P G + G G+ A A G P
Sbjct: 95 ARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAP 154
Query: 57 GG-AEPGEDTALLRLLGLRRGLRRLRRLWAGPRVQRGRGRGRGRGWGPSRGCVPEEESSD 115
G A+P AL G GP G G G G G GP + P +
Sbjct: 155 AGPAKPAGPAALAARAG------------PGP----GPGPGPGPGPGPGKPAGPGAAQTL 198
Query: 116 GESDEEEFQGFHSDEDVAPSSLRSALRSQRGRAPRGRGRKHKTTPLPPPRLADVAPTPPK 175
S + A ++ P + T PP + AP P
Sbjct: 199 NGS-----AALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPA 253
Query: 176 TPARKRGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQ 235
P+ A AP AP + P + RPPG PAGP
Sbjct: 254 APSPPA------------------APAPAAPAAAPPPPPPAPATLARPPGHPAGP----- 290
Query: 236 QAVVVAEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGR 295
P PPP Q G G P P P GG + G+ G G
Sbjct: 291 ----------PTAAPAVPPPAAA---QNGG---SAGAAPAP-APAAGGPAGVSGQPGPGA 333
Query: 296 GRGGGLPFVIKFVSRAKKVKMGQLSLGLESGQGQGQHEESWQDVPQRRVGSGQGGSPCWK 355
P V K S + V+ + + G S P + QG P
Sbjct: 334 AAAAPAPGV-KAESPKRVVQAAPPAAQTLAASGPASTAASMVIGP-----TMQGALP--- 384
Query: 356 KQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPP 415
+ K G + +++ A L P L P P PP
Sbjct: 385 -SPAAVPPPAPGTPTGLPKGAAGAVTQ--SLSRTPTATTSGIRATLTPTVLAPRLPQPPQ 441
Query: 416 --------PLPP--------------------------PSTSPPPPLCPPPPPPVSPPPL 441
LPP P + P P P S PP+
Sbjct: 442 NPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPV 501
Query: 442 -------PSPP-------PPPAQEEQEESPPPVVP-ATCSRKRGRPPLTPSQRAEREAAR 486
P P P ++ ++ V P AT R G P A + A+
Sbjct: 502 QISTVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASL 561
Query: 487 AGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRF 546
T+ T TP G S + A ++ +K + F+ ++ SS T
Sbjct: 562 G--TATAVQTGTPQRTVPGATTTS-SAATETMENVKKCKNFLSTLIKLASSGKQST---- 614
Query: 547 MDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILRE 606
+ K V +L I + + S P+ P LP R+ L
Sbjct: 615 ---ETAANVKELVQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQ--LTP 669
Query: 607 PTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVL 666
+ + +++ PPPP + A + A SS T + A S+
Sbjct: 670 DSAAFIQQSQQQPPPPTS----QATTALTAVVLSSSVQRTAGKTAATVTSALQPPVLSLT 725
Query: 667 TPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPA 726
P +G + +P P P+P A+ R ++L + TP+ A PH
Sbjct: 726 QPTQVGVGKQGQPTPLVIQQ---PPKPGALIRPPQVTLTQ------TPMVALRQPHNRIM 776
Query: 727 LSNGPQTQAQLLQPLQALQTQLLP 750
L+ Q Q LQP+ ++ +LP
Sbjct: 777 LTTPQQIQLNPLQPVPVVKPAVLP 800
Score = 33.5 bits (75), Expect = 2.9
Identities = 15/28 (53%), Positives = 17/28 (60%)
Query: 1 MAAAAGGGSCPGPGSARGRFPGRPRGAG 28
+AA AG G PGPG G PG+P G G
Sbjct: 166 LAARAGPGPGPGPGPGPGPGPGKPAGPG 193
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 103 bits (258), Expect = 2e-21
Identities = 133/558 (23%), Positives = 200/558 (35%), Gaps = 88/558 (15%)
Query: 347 GQGGSPCWKKQEQKLDDEEEEKKEEEEKDKEG-----EEKEERAVAEEMMPAAEKEEAKL 401
G S E D E+ + E K K+ E+K+ + M A +
Sbjct: 697 GFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQ 756
Query: 402 PPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVV 461
PPPP P PPPP PP PPP PPP P P PPP Q P +
Sbjct: 757 PPPP---PQQPPPPP-PPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQL 812
Query: 462 PATCSRKRGR--PPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTT 519
P + G P+ + E P S P A PP
Sbjct: 813 PGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPA----------- 861
Query: 520 FLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVL-RPPITTSPPVPQEPA 578
+ + S S+R P + P +PP VSP L + P+ PP+ Q P
Sbjct: 862 ----LHNALPQQPSRPSNRAAALPPK-----PARPP--AVSPALTQTPLLPQPPMAQPPQ 910
Query: 579 PVPSPPRAPTPPSTPVPLPEKRRSI--LREPTFRWTSLTRELPPPPPAPPPP-------- 628
+ P PP T + + + + ++ PT S+ + PPPP PPPP
Sbjct: 911 VLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQL 970
Query: 629 ---PAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYE---SVLTPPPLGAPEAPEPEPP 682
P P PPP P +P + Q P HL+ + + PPP P+ +P P
Sbjct: 971 QQQPPPPPPPQP-----QPPPQQQHQPPPRPVHLQPMQFSTHIQQPPP---PQGQQPPHP 1022
Query: 683 PADDSPAEPEPRAVGRT-NHLSLPRF---APVVTTPVKAEVSPHGAPALSNGPQTQAQLL 738
P P P+P + H PR P T ++ S P + + PQ +
Sbjct: 1023 PPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPS----PLMIHSPQ-----M 1073
Query: 739 QPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGVGSLPLSGVEEKMFSLLKR 798
Q+L Q PQ P+ Q S Q PL + EEK+ S + R
Sbjct: 1074 SQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVK------------EEKIHSPIIR 1121
Query: 799 AK-----VQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISDRGPVRSEDESVEAKR 853
++ ++ + K +P P + +V V + ++ + ++
Sbjct: 1122 SEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQK 1181
Query: 854 ERPSGPESPVQGPRIKHV 871
+ P P +P + +IK++
Sbjct: 1182 QEPKTPVAPKKDLKIKNM 1199
Score = 89.4 bits (220), Expect = 5e-17
Identities = 122/481 (25%), Positives = 176/481 (36%), Gaps = 79/481 (16%)
Query: 352 PCWKKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAP 411
P K ++K D++E+KKE+ ++ +E EE ++ E +K + PAP
Sbjct: 531 PQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAP 590
Query: 412 SPPPPLPPPSTSPPPPLCPP----------------PPPPVS---------PPPLPSPPP 446
P PP S C P P + P L + P
Sbjct: 591 MKSKP-PPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNP 649
Query: 447 PPAQEEQEESPPPVV------PATCSRKRGRPPLTPSQRAEREAARAGPEG-TSPPTPTP 499
+ + E P + +C RK+ +P +++ + A + +G +S + +
Sbjct: 650 DEIEIDFETLKPSTLRELERYVTSCLRKKRKP---QAEKVDVIAGSSKMKGFSSSESESS 706
Query: 500 STATGGPPEDSPT-VAPKS-------TTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDP 551
S ++ EDS T +APKS K+ + A + + P P
Sbjct: 707 SESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPP 766
Query: 552 PKPPKVEVSPVLRPPITTSPPVPQEPAP-VPSPPRAPTPPSTPVPLPEKRRSILREPTFR 610
P PP+ + P PP P +PQ+ AP + S P PV P+ S+ +P
Sbjct: 767 PPPPQQQQQP---PPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVF-DPIGH 822
Query: 611 WTSLTRELPPP--PPAPPPPPAPSPPP---------APATSSRRPL-----LLRAPQFTP 654
+T LP P PP P PP S PP PA + P RA P
Sbjct: 823 FTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPP 882
Query: 655 SEAHLKIYESVLTPPPLGAPEAPEPEPPPA---DDSPAEPEPRAVGRTNHLSLPRFAPV- 710
A LT PL P+ P +PP D+ P P P L L + V
Sbjct: 883 KPARPPAVSPALTQTPL-LPQPPMAQPPQVLLEDEEP--PAPPLTSMQMQLYLQQLQKVQ 939
Query: 711 VTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMP 770
TP+ V P P P ++Q QL Q PPP PQ QPPP Q P
Sbjct: 940 PPTPLLPSVKVQSQPPPPLPP-------PPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQP 992
Query: 771 P 771
P
Sbjct: 993 P 993
Score = 64.7 bits (156), Expect = 1e-09
Identities = 114/489 (23%), Positives = 178/489 (36%), Gaps = 77/489 (15%)
Query: 356 KQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPP 415
+Q L ++ K +++EKDK+ E+K+E+ +E + +K +AK PPP T S
Sbjct: 523 EQLAALSQPQQNKPKKKEKDKK-EKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNS 581
Query: 416 PLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLT 475
+ P P+ S PPP + E+E+ P+ S + R
Sbjct: 582 NVSKKE----------------PAPMKSKPPPTYESEEEDKCKPM-----SYEEKRQLSL 620
Query: 476 PSQRAEREAARAGPEGTSPPTPTPSTATGGPPE---DSPTVAPKSTTFLKNIRQFIMPVV 532
+ E + G + PS P E D T+ P + L+ + +++ +
Sbjct: 621 DINKLPGE--KLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPST---LRELERYVTSCL 675
Query: 533 SARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPST 592
+ P+ KV+V + E + S + +
Sbjct: 676 RKKRK--------------PQAEKVDVI-AGSSKMKGFSSSESESSSESSSSDSEDSETE 720
Query: 593 PVPLPEKRRSILREPTFRWTSLTRELPPPP-PAP---PPPPAPSPPPAPATSSRRPLLLR 648
P +K+ RE +++ P P P PPPP PPP P ++P
Sbjct: 721 MAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPP 780
Query: 649 APQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFA 708
P P +A + S PPP A + P E P S +P HL P
Sbjct: 781 PPPSMPQQAAPAMKSS---PPPFIATQVPVLE-PQLPGSVFDPIGHFTQPILHLPQPELP 836
Query: 709 PVVTTPVKAEVSPH-------GAPALSNG-PQTQAQLLQPLQALQTQLLPQALPPPQPQL 760
P + P + PH PAL N PQ ++ AL PP+P
Sbjct: 837 PHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAAL----------PPKPAR 886
Query: 761 QPPPSP--QQMPPLEKARIAGVGSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASM 818
P SP Q P L + +A + L EE L ++QL+ QQ QKV
Sbjct: 887 PPAVSPALTQTPLLPQPPMAQPPQVLLED-EEPPAPPLTSMQMQLY---LQQLQKVQPPT 942
Query: 819 PLSPGGQME 827
PL P +++
Sbjct: 943 PLLPSVKVQ 951
Score = 61.2 bits (147), Expect = 1e-08
Identities = 62/220 (28%), Positives = 86/220 (39%), Gaps = 49/220 (22%)
Query: 360 KLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPP---- 415
+L EE E + K + G ++E A+ + PP P P+PPP
Sbjct: 163 ELPTEETEIMIVQAKGR-GRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQAT 221
Query: 416 PLPPPSTSP-------------PPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVP 462
P P P+ +P P PL PPP P P P P+P P P Q S PP++
Sbjct: 222 PHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQ-----SHPPIIA 276
Query: 463 ATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLK 522
AT P+ + +R+A P P PS PPE PK TT L
Sbjct: 277 AT------PQPVKTKKGVKRKADTTTPTTIDPIHEPPSL----PPE------PK-TTKLG 319
Query: 523 NIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPV 562
R+ SSR +K P++ + + P + S V
Sbjct: 320 QRRE---------SSRPVKPPKKDVPDSQQHPAPEKSSKV 350
Score = 61.2 bits (147), Expect = 1e-08
Identities = 52/177 (29%), Positives = 71/177 (40%), Gaps = 21/177 (11%)
Query: 556 KVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLT 615
K VS V ++PP Q P P P P +A TP P P ++ +
Sbjct: 190 KPGVSTVPNTTQASTPPQTQTPQPNPPPVQA-----TPHPFPAVTPDLIVQTPVMTVVPP 244
Query: 616 RELPPPPPAPP---PPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLG 672
+ L PPP PP PPPAP+P P S P++ PQ ++ +K TP +
Sbjct: 245 QPLQTPPPVPPQPQPPPAPAPQP---VQSHPPIIAATPQPVKTKKGVKRKADTTTPTTID 301
Query: 673 APEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSN 729
P EPP P EP+ +G+ S P P P + H AP S+
Sbjct: 302 ----PIHEPP---SLPPEPKTTKLGQRRESSRPVKPPKKDVP---DSQQHPAPEKSS 348
Score = 53.5 bits (127), Expect = 3e-06
Identities = 128/579 (22%), Positives = 184/579 (31%), Gaps = 144/579 (24%)
Query: 1896 HHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTS 1955
HH + P P + P P PPP + PP PPP S+ P
Sbjct: 741 HHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPP-------PPPPPPSMPQQAAPAM 793
Query: 1956 GELAPPGPAPSPP--PPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAM 2013
PP A P P+ G F+ + F +L Q E+
Sbjct: 794 KSSPPPFIATQVPVLEPQLPGSVFDPIG----------HFTQPILHLP--QPELPPHLPQ 841
Query: 2014 GSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAE 2073
H P ++ VVS P L +A P P S
Sbjct: 842 PPEHSTPPHLNQH-------------AVVSPPAL-HNALPQQP----------SRPSNRA 877
Query: 2074 AVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPRE 2133
A P+ P P + + +L +PP P +++ E
Sbjct: 878 AALPPKPARPPAVSPALTQTPLL------PQPPMAQPPQVL-----------------LE 914
Query: 2134 ESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIIL 2193
+ PPAPPL + P P P V+V S P P PP P S
Sbjct: 915 DEEPPAPPLTSMQMQLYLQQLQKVQPP-----TPLLPSVKVQSQPPPPLPPPPHPS---- 965
Query: 2194 VNKLGQVFVKMAGEGEPVPPPVKQ---PPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVR 2250
V + Q +P PPP +Q PP P + P ++ P P G P
Sbjct: 966 VQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPG 1025
Query: 2251 PAPPPPPP--PLTLVL--------SSGPAS-------PPRQAIRVKRVSTFSGRSPPAPP 2293
PPPP P P ++ S P S P I ++S F + +PP
Sbjct: 1026 QQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPP 1085
Query: 2294 PYKA-PRLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRG-----VLDLDRPGEPAGEE 2347
P+ E AS PQ + ++ +P +R L + P P +
Sbjct: 1086 QQNVQPKKQELRAASVVQPQPLVV----VKEEKIHSPIIRSEPFSPSLRPEPPKHPESIK 1141
Query: 2348 SPGPLQERSPLLPLPEDGP---PQVPDGPPDLLLESQWHHYSGEASSSEEEPPSPD-DKE 2403
+P L +R + P+ P P + PP P +PD DK+
Sbjct: 1142 APVHLPQRPEMKPVDVGRPVIRPPEQNAPP---------------------PGAPDKDKQ 1180
Query: 2404 NQAPKR-TGPHLRFEISSEDGFSVEAESLEGAWRTLIEK 2441
Q PK P +I + G+W +L++K
Sbjct: 1181 KQEPKTPVAPKKDLKIKN-----------MGSWASLVQK 1208
Score = 48.1 bits (113), Expect = 1e-04
Identities = 33/124 (26%), Positives = 47/124 (37%), Gaps = 12/124 (9%)
Query: 401 LPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQ--EESPP 458
+PP PL P P PP P PPP+ P P P S PP+ + P P + ++ +
Sbjct: 242 VPPQPLQTPPPVPPQPQPPPA--------PAPQPVQSHPPIIAATPQPVKTKKGVKRKAD 293
Query: 459 PVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKST 518
P T P L P + + R E + P P +P + K +
Sbjct: 294 TTTPTTIDPIHEPPSLPPEPKTTKLGQRR--ESSRPVKPPKKDVPDSQQHPAPEKSSKVS 351
Query: 519 TFLK 522
LK
Sbjct: 352 EQLK 355
Score = 45.4 bits (106), Expect = 7e-04
Identities = 53/222 (23%), Positives = 74/222 (33%), Gaps = 55/222 (24%)
Query: 1790 EEPAHLEAAEENQT--------IVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNL 1841
E P HL E+ T +V PA + P P + +P P R +
Sbjct: 834 ELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPA 893
Query: 1842 --DPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPL---------PSPGS 1890
PL P A PP ++ + + P PL + P+P
Sbjct: 894 LTQTPLLPQPPMAQPP--------QVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLL 945
Query: 1891 PSSLTHHIPTVGDPDFPAPPRRSRR---------PSPLAPRPPPSRWASPP--------L 1933
PS P P P PP S + P P P+PPP + PP +
Sbjct: 946 PSVKVQSQPP---PPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPM 1002
Query: 1934 KTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGP 1975
+ S ++ PPP P + P P PPPP+ P
Sbjct: 1003 QFSTHIQQPPP--------PQGQQPPHPPPGQQPPPPQPAKP 1036
Score = 41.6 bits (96), Expect = 0.011
Identities = 51/191 (26%), Positives = 65/191 (34%), Gaps = 25/191 (13%)
Query: 1789 REEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPD 1848
RE+ H + +P P PP + PP P P ++ P
Sbjct: 733 REQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPA 792
Query: 1849 SGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVG-DPDFP 1907
S+PPP +VP P L G F P+ G + H+P P P
Sbjct: 793 MKSSPPPF------IATQVPVLEPQ---LPGSVFDPI---GHFTQPILHLPQPELPPHLP 840
Query: 1908 APPRRSRRP---SPLAPRPPPSRWASPPLKTSPQLR---VPP----PTSVVTALTPTSGE 1957
PP S P PP A P + P R +PP P +V ALT T
Sbjct: 841 QPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQT--P 898
Query: 1958 LAPPGPAPSPP 1968
L P P PP
Sbjct: 899 LLPQPPMAQPP 909
Score = 39.3 bits (90), Expect = 0.053
Identities = 33/115 (28%), Positives = 50/115 (43%), Gaps = 17/115 (14%)
Query: 2209 EPVPPPVKQPPLP-PTISPT----APTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTL- 2262
+P PPPV+ P P P ++P P +PP PL PV +P P P P P+
Sbjct: 212 QPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSH 271
Query: 2263 --VLSSGPASPPRQAIRVKRVSTFS--------GRSPPAPPPYKAPRLDEDGEAS 2307
++++ P P + VKR + + P PP K +L + E+S
Sbjct: 272 PPIIAATP-QPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESS 325
Score = 38.9 bits (89), Expect = 0.070
Identities = 48/189 (25%), Positives = 67/189 (35%), Gaps = 29/189 (15%)
Query: 454 EESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTV 513
EE+ +V A R RGR ++ T P T TP PP T
Sbjct: 167 EETEIMIVQAK-GRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQP---NPPPVQATP 222
Query: 514 APKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPV 573
P I Q PV++ + ++TP PP PP+ + PP
Sbjct: 223 HPFPAVTPDLIVQ--TPVMTVVPPQPLQTP-------PPVPPQPQ------PP------- 260
Query: 574 PQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSP 633
PAP P P ++ P P P K + ++ T T + PP+ PP P +
Sbjct: 261 ---PAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTK 317
Query: 634 PPAPATSSR 642
SSR
Sbjct: 318 LGQRRESSR 326
Score = 38.9 bits (89), Expect = 0.070
Identities = 80/363 (22%), Positives = 122/363 (33%), Gaps = 61/363 (16%)
Query: 132 VAPSSLRSALRSQRGRAPRGRGRKHKTTPLPPPRLAD------VAPTPPKTPARKRGEEG 185
V+P +L +AL Q R P R P PP ++ + P PP + E
Sbjct: 857 VSPPALHNALPQQPSR-PSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLED 915
Query: 186 TERMVQALTELLRRAQAPQAPRSRACEPSTP--RRSRGRPPGRPAGPCRRKQQAVVVAEA 243
E LT + + Q + + P P + PP P P QQ +
Sbjct: 916 EEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPP 975
Query: 244 AVTIPKPEPP------PPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGR 297
P+P+PP PP PV Q + P P +G Q G +
Sbjct: 976 PPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPP----PPQGQQPPHPPPGQQPPPP 1031
Query: 298 GGGLPFVIKFVSRAKKVKMGQLSLGLESGQGQGQHEESWQDVPQRRVGSG---QGGSPCW 354
P Q QH S + +G + SP
Sbjct: 1032 QPAKP------------------------QQVIQHHHSPRHHKSDPYSTGHLREAPSPLM 1067
Query: 355 KKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVA-EEMMPAAEKEEAKLPPPPL--TPPAP 411
Q + + +++ + +++E RA + + P +E K+ P + P +P
Sbjct: 1068 IHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSP 1127
Query: 412 S--PPPPLPPPSTSPPPPLCPPPP--------PPVSPPPLPSPPP--PPAQEEQEESPPP 459
S P PP P S P L P P + PP +PPP P ++++E P
Sbjct: 1128 SLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTP 1187
Query: 460 VVP 462
V P
Sbjct: 1188 VAP 1190
Score = 35.8 bits (81), Expect = 0.59
Identities = 30/89 (33%), Positives = 36/89 (40%), Gaps = 11/89 (12%)
Query: 689 AEPEPRAVGRTNHLSLPRFAPVVTTPVK----AEVSPHGAPALSNG--PQTQAQLLQPLQ 742
A+P V T S P P TP + +PH PA++ QT + P Q
Sbjct: 189 AKPGVSTVPNTTQASTP---PQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQ 245
Query: 743 ALQTQLLPQALPPPQPQLQPPPSPQQMPP 771
LQT P P PQP P P P Q P
Sbjct: 246 PLQTP--PPVPPQPQPPPAPAPQPVQSHP 272
Score = 34.7 bits (78), Expect = 1.3
Identities = 46/187 (24%), Positives = 67/187 (35%), Gaps = 32/187 (17%)
Query: 2108 DLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLP 2167
+LP+E + ++ G G G R+E+ P ++ +Q T P +T P
Sbjct: 163 ELPTEETEIMIVQAKGRGRG----RKETGTAKPGVSTVPNTTQAST-----PPQTQTPQP 213
Query: 2168 GAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISP- 2226
P V+ P P T +I+ + V + P PP QPP P P
Sbjct: 214 NPPPVQA-----TPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPV 268
Query: 2227 -TAPTSWTLPPGPL---LGVLPVVGVVRPA--------PPPPPPPLTLVL-----SSGPA 2269
+ P P P+ GV P P PP P T L SS P
Sbjct: 269 QSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPV 328
Query: 2270 SPPRQAI 2276
PP++ +
Sbjct: 329 KPPKKDV 335
Score = 34.7 bits (78), Expect = 1.3
Identities = 38/141 (26%), Positives = 55/141 (39%), Gaps = 29/141 (20%)
Query: 1846 RPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPD 1905
R ++G+A P VPN + + P + P P+P + H P V PD
Sbjct: 183 RKETGTAKPGVST--------VPNTTQASTPPQTQT--PQPNPPPVQATPHPFPAV-TPD 231
Query: 1906 F----------PAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVT------ 1949
P P ++ P P P+PPP+ A P+++ P + P V T
Sbjct: 232 LIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAP-APQPVQSHPPIIAATPQPVKTKKGVKR 290
Query: 1950 -ALTPTSGELAPPGPAPSPPP 1969
A T T + P PS PP
Sbjct: 291 KADTTTPTTIDPIHEPPSLPP 311
Score = 32.7 bits (73), Expect = 5.0
Identities = 37/166 (22%), Positives = 49/166 (29%), Gaps = 47/166 (28%)
Query: 1810 PSSEPPGGEDPPLDTDVLVPGAPERHSP---IQNLDPPLRPDSG-----------SAPPP 1855
P P P L L+P P P +++ +PP P + PP
Sbjct: 882 PKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPP 941
Query: 1856 APRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRR 1915
P S +KV + P P P P P L P P PP++ +
Sbjct: 942 TPLLPS---VKVQSQPPPPLP-------PPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQ 991
Query: 1916 PSPLA-----------------------PRPPPSRWASPPLKTSPQ 1938
P P P PPP + PP PQ
Sbjct: 992 PPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQ 1037
Score = 32.0 bits (71), Expect = 8.5
Identities = 36/149 (24%), Positives = 62/149 (41%), Gaps = 24/149 (16%)
Query: 1003 RKCDKIEARKMERLAKKGRTIVKTLLPWDSDESPEASPGPPGPRRGAGAGGPREEVVAHP 1062
RK K +A K++ +A G + +K +S+ S E+S A P+ + HP
Sbjct: 676 RKKRKPQAEKVDVIA--GSSKMKGFSSSESESSSESSSSDSEDSETEMA--PKSKKKGHP 731
Query: 1063 GPEEQDSLLQRKSARRCVKQRPSYDIFEDSDDSEPGGPPAPRRRTPRENELPLPEPEEQS 1122
G E++ + ++Q P+ P PP P ++ P P P P++Q
Sbjct: 732 GREQKK---HHHHHHQQMQQAPA---------PVPQQPPPPPQQPP-----PPPPPQQQQ 774
Query: 1123 RPRKPTLQPVLQLKARRRLDKDALAPGPF 1151
+P P P + +A + +P PF
Sbjct: 775 QPPPPPPPPSMPQQAAPAMKS---SPPPF 800
>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
Length = 1682
Score = 102 bits (253), Expect = 7e-21
Identities = 154/600 (25%), Positives = 220/600 (36%), Gaps = 96/600 (16%)
Query: 397 EEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPV--SPPPLPSPPPPPAQEEQE 454
+++ PP P TP S S+SP P+ PPPP + S PLP PP P AQ Q+
Sbjct: 538 QDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSP-AQNPQD 596
Query: 455 ESPPPVVPATCSRKRGRPPLTPSQRAEREAAR-AGPEGTSPPTPTPSTATGGPPEDSPTV 513
PP+VP T + PP PS + + PE P P T GP P
Sbjct: 597 ---PPLVPLTLAL----PPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGP---GPPP 646
Query: 514 APKSTTFLKNIRQFIMPVVS---ARSSRVIKTPRRFMDEDPPKPPKVEVSP-----VLR- 564
P L Q + P V AR R+ P +++ +P + ++ P +++
Sbjct: 647 GP-----LSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKM 701
Query: 565 ---------------PPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTF 609
+ PP+ + A + SP T P+T P + T
Sbjct: 702 LDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTT 761
Query: 610 RWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAH-LKIYESVLTP 668
T + PPP PPPP A PPP S +P P PS A LK SVL
Sbjct: 762 TATQEEEKKPPPALPPPPPLAKFPPP----SQPQP----PPPPPPSPASLLKSLASVLEG 813
Query: 669 PP-----LGAPEAPEPEP-PPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPH 722
GA + P P P SP P G T +LP P A S
Sbjct: 814 QKYCYRGTGAAVSTRPGPLPTTQYSPGPPS----GAT---ALP--------PTSAAPSAQ 858
Query: 723 GAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGVGS 782
G+P S +Q A + + + +P P QPPP P +PP AR
Sbjct: 859 GSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPP-PLSLPP---ARSESEVL 914
Query: 783 LPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISDRGPV 842
+S E + + R+ + + + L P Q +E AG V +S
Sbjct: 915 EEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKEEAGGVAAVSGSCKR 974
Query: 843 RSEDESVEAKRERPSGPESPVQGPRIKHVCRHAAVALGQARAMVPEDVPRLSALPLRDRQ 902
R ++ E +R R + +S + PR + RA VP+ + +
Sbjct: 975 RQKEHQKEHRRHRRACKDSVGRRPR-------------EGRAKAKAKVPKEKSRRVLGNL 1021
Query: 903 DLATEDTSSASETESVPSRSRRGKVEAAGPGGESEPTGSGGTLAHTPRRSLPSHHGKKMR 962
DL +E+ ++ + + K A P S P S P S+P GKK R
Sbjct: 1022 DLQSEEIQGREKSRPDLGGASKAKPPTA-PAPPSAPAPSAQPT--PPSASVP---GKKAR 1075
Score = 94.4 bits (233), Expect = 1e-18
Identities = 215/920 (23%), Positives = 282/920 (30%), Gaps = 259/920 (28%)
Query: 397 EEAKLPPPPLTPPAPSPPPPLPPPSTSPP-PPLCPPPPPPVSPPPLPSP----------- 444
E+ LPP PP P PPPP PPP PP P L PP ++ P L S
Sbjct: 236 EQTGLPPGLPLPPPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERK 295
Query: 445 -PPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPST-- 501
PP ++EQ S P P PP A P G P P +
Sbjct: 296 GSAPPERQEQRHSLPHPYPYPAPAYTAHPP-------GHRLVPAAPPGPGPRPPGAESHG 348
Query: 502 ---ATGGPPED-----------SPTVAPKSTTFLKNIRQFIMP-----VVSARSSRVIKT 542
AT P D +V+P +TT P S+ SS T
Sbjct: 349 CLPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNT 408
Query: 543 PRRFMDEDPPKP-------PKVEVS--------------PVLRPPITTS----PPVPQEP 577
R ++ +P P P +EVS P L P T PP P P
Sbjct: 409 GLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSP 468
Query: 578 APVPSPP--RAPTPPS------------------------------TPVPLPEKRRSILR 605
P P P R P PP+ P PLP R L
Sbjct: 469 PPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPH-REGFLG 527
Query: 606 EPTFRWTSLTRE--LPPPPPAP----------------------PPPP------APSP-P 634
P R++ T++ PP PP P PPPP P P P
Sbjct: 528 PPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRP 587
Query: 635 PAPATSSRR----PLLLRAPQFTPSEAHLKIYESVLTP----PPLGAPEAPE--PEPPPA 684
P+PA + + PL L P PS H S P P + P+ PE P PPP
Sbjct: 588 PSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPG 647
Query: 685 DDSPA-EPEPRAVGRTNHLSLPRFAPVVTTPVKAE--------VSPHGAPALSN------ 729
S A +P P VG PR TP++ + + P G +
Sbjct: 648 PLSKAPQPVPPGVGELPARG-PRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESI 706
Query: 730 -----------GPQTQAQLLQPLQALQT-------------------------------- 746
G Q L +P +LQ+
Sbjct: 707 RKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQE 766
Query: 747 --QLLPQALPPPQPQLQ-PPPSPQQMPPLEKARIAGVGSLPLSGVEEKMF-----SLLKR 798
+ P ALPPP P + PPPS Q PP A + S +E + +
Sbjct: 767 EEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVS 826
Query: 799 AKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISDRGPVRSEDESVEAKRERPSG 858
+ Q + + L P G+ + + S A RER +G
Sbjct: 827 TRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWA-RERRAG 885
Query: 859 PESPVQGPRIKHVCRHAAVALGQARAMVPEDVPRLSALPLRDRQDLATEDTSSASETESV 918
E PV GP M P P +LP + E+ S A ET +
Sbjct: 886 -EEPVPGP------------------MTPTQPPPPLSLPPARSESEVLEEISRACET--L 924
Query: 919 PSRSRRGKVEAAGPGGESEPTGSGGTLAHTPRRSLPSHHGKKMRMARCGHCRGCLRVQD- 977
R R + A P +EP SG R LP K+ C R Q
Sbjct: 925 VERVGRSATDPADPVDTAEPADSG------TERLLPPAQAKEEAGGVAAVSGSCKRRQKE 978
Query: 978 -----------CGSCVNCLDKPKFGGPNTKKQCCVYR----------KCDKIEARKMERL 1016
C V +P+ G K + + + ++I+ R+ R
Sbjct: 979 HQKEHRRHRRACKDSVG--RRPREGRAKAKAKVPKEKSRRVLGNLDLQSEEIQGREKSRP 1036
Query: 1017 AKKGRTIVKTLLPWDSDESPEASPGPPGPRRGAGAGGPREEVVAHPGPEEQDSLLQRKSA 1076
G + K +P S P P REE PG D L R +
Sbjct: 1037 DLGGASKAKPPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPGPPGVSRADMLKLRSLS 1096
Query: 1077 RRCVKQRPSYDIFEDSDDSE 1096
K+ I +S D E
Sbjct: 1097 EGPPKELKIRLIKVESGDKE 1116
Score = 76.3 bits (186), Expect = 4e-13
Identities = 181/740 (24%), Positives = 237/740 (32%), Gaps = 183/740 (24%)
Query: 1808 PAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQN--LDPPLRPDSGSA----PPPAPRSFS 1861
P P PPG E PG+ R S +Q +D + P + +A P P
Sbjct: 335 PGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLP 394
Query: 1862 GARIKVPNYSPSRRPLGGVSFGPLPSPGSPSS---------LTHH-----------IPTV 1901
G + S S L GV P+PG P + ++HH P +
Sbjct: 395 GTTTSSSSSSSSNTGLRGVE----PNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFL 450
Query: 1902 GDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTA----LTPTSGE 1957
G P A P S P P +P PPP P L LR PPP + + GE
Sbjct: 451 GAP--AATPHLSLPPGPSSPPPPPC----PRL-----LRPPPPPAWLKGPACRAAREDGE 499
Query: 1958 L---------APPGPAPSPPPPED--LGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEE 2006
+ PP PAP P P + LGP S S D P
Sbjct: 500 ILEELFFGTEGPPRPAPPPLPHREGFLGPP------ASRFSVGTQDSHTPPTPPTP---- 549
Query: 2007 IVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDD 2066
SS+ G S + P S FP A + P P +P
Sbjct: 550 -----TTSSSNSNSGSHSSSPAGPVS----FPPPPYLARSIDPLPRPPSP---------- 590
Query: 2067 GTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGD 2126
+ + P PP+ P G+ R PE P V F GPG
Sbjct: 591 -AQNPQDPPLVPLTLALPPAPPSSCHQNTSGSF----RRPES-PRPRVSFPKTPEVGPG- 643
Query: 2127 GGAGPREESLPPAPPLANGSQP-SQGLTASPADPTRTFAWLPGAPGVRVLSLGPAP---E 2182
PP PL+ QP G+ PA G R+ P P +
Sbjct: 644 ----------PPPGPLSKAPQPVPPGVGELPAR------------GPRLFDFPPTPLEDQ 681
Query: 2183 PPKPATSKII---LVNKLGQVFVKMAGE--------GEPVPPPVKQP------PLP---- 2221
+PA KI+ L N + + + E G PP+K+P P P
Sbjct: 682 FEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTA 741
Query: 2222 -----PTISPTAPTSWT----------------LPPGPLLGVLPVVGVVRPAPPPPPPPL 2260
P ++ T T+ T LPP P L P +P PPPPP P
Sbjct: 742 PTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSPA 801
Query: 2261 TLVLSSGPASPPRQAIRVKRVSTFSGRSPPAP-------PPYKAPRLDEDGEA--SEDTP 2311
+L+ S ++ + S R P P PP A L A ++ +P
Sbjct: 802 SLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSP 861
Query: 2312 QVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEES-PGPLQERSPLLPLPEDGPPQVP 2370
Q S FS T G +R AGEE PGP+ P P P PP
Sbjct: 862 QPSASSSSQFS-------TSGGPWARER---RAGEEPVPGPMTPTQP--PPPLSLPPARS 909
Query: 2371 DGPPDLLLESQWHHYSGEASSSEEEPPSPDDKENQAPKRTGPHLRFEISSEDGFSVEAES 2430
+ + S +P P D A T L + E+ V A S
Sbjct: 910 ESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKEEAGGVAAVS 969
Query: 2431 LEGAWRTLIEKVQEARGHAR 2450
R E +E R H R
Sbjct: 970 -GSCKRRQKEHQKEHRRHRR 988
Score = 62.4 bits (150), Expect = 6e-09
Identities = 169/737 (22%), Positives = 238/737 (32%), Gaps = 146/737 (19%)
Query: 115 DGESDEEEFQGFHSDEDVAPSSL---RSALRSQRGRAPRGRGRKHKTTPLPPPRLADVAP 171
DGE EE F G AP L L R G H T P PP
Sbjct: 497 DGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSH-TPPTPP-------- 547
Query: 172 TPPKTPARKRGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPRRSRGRPP-GRPAGP 230
TP T + G+ + +P P S P P +R P RP P
Sbjct: 548 TP--TTSSSNSNSGSH------------SSSPAGPVSF---PPPPYLARSIDPLPRPPSP 590
Query: 231 CRRKQQAVVVAEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGR 290
+ Q +V +T+ P P PP ++ +GS++ E P P P+
Sbjct: 591 AQNPQDPPLVP---LTLALP-PAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPP 646
Query: 291 GGRGRGRGGGLPFVIKFVSRAKKVKMGQLSLGLESGQGQGQHEESWQDVPQRRVGSGQGG 350
G + P V + +R ++ + Q + ++ +P G
Sbjct: 647 GPLSKAPQPVPPGVGELPARGPRL----FDFPPTPLEDQFEEPAEFKILPD-------GL 695
Query: 351 SPCWKKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPP- 409
+ K ++ + EEE+++ E + KE A + P P +T
Sbjct: 696 ANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTT 755
Query: 410 -------APSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVP 462
A PPP+ PPPPL PPP P P PPPPP+ +S V+
Sbjct: 756 TTTTTTTATQEEEKKPPPALPPPPPLAKFPPP---SQPQPPPPPPPSPASLLKSLASVLE 812
Query: 463 AT--CSRKRGRPPLTPSQRAEREAARAGPEGTSPPTP-TPSTATGGPPEDSPTVAPKSTT 519
C R G T R GP T+ +P PS AT PP + A S
Sbjct: 813 GQKYCYRGTGAAVST----------RPGPLPTTQYSPGPPSGATALPPTSAAPSAQGS-- 860
Query: 520 FLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAP 579
P SA SS T P +EP P
Sbjct: 861 ----------PQPSASSSSQFSTS--------------------GGPWARERRAGEEPVP 890
Query: 580 VPSPPRAPTPP-STPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPA 638
P P P PP S P P + S + E R E P P + PA +
Sbjct: 891 GPMTPTQPPPPLSLP---PARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADS 947
Query: 639 TSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPAD----DSPAEPEPR 694
+ R L PP EA + E R
Sbjct: 948 GTER-----------------------LLPPAQAKEEAGGVAAVSGSCKRRQKEHQKEHR 984
Query: 695 AVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQL--LPQA 752
R S+ R KA+V + + Q++ +Q + + L +A
Sbjct: 985 RHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGNLDLQSEEIQGREKSRPDLGGASKA 1044
Query: 753 LPP--PQPQLQPPPSPQQMPPL-----EKARIAGVGSLPLSGVEE-KMFSLL----KRAK 800
PP P P P PS Q PP +KAR G +S + K+ SL K K
Sbjct: 1045 KPPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPGPPGVSRADMLKLRSLSEGPPKELK 1104
Query: 801 VQLFKIDQQQQQKVAAS 817
++L K++ ++ AS
Sbjct: 1105 IRLIKVESGDKETFIAS 1121
Score = 62.0 bits (149), Expect = 8e-09
Identities = 153/645 (23%), Positives = 196/645 (30%), Gaps = 204/645 (31%)
Query: 1775 WYRCRILEYRPWGPREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPER 1834
W + R +G + ++ A E + P + P GE+ L PG R
Sbjct: 177 WNLLHLEHKRNYGAKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEG------LSPGGKRR 230
Query: 1835 HS---------PIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGP- 1884
P L PP P PPP P PL G++ P
Sbjct: 231 RGCNSEQTGLPPGLPLPPPPLPPPPPPPPPPP-----------------PPLPGLATSPP 273
Query: 1885 --LPSPGSPSSLTHHIPTVGDPDFPAPPRRSRR----PSPLAPRPPPSRWASPPLKTSPQ 1938
L PG S+L H + APP R + P P P P P+ A P P
Sbjct: 274 FQLTKPGLWSTL-HGDAWGPERKGSAPPERQEQRHSLPHPY-PYPAPAYTAHP-----PG 326
Query: 1939 LRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLL 1998
R+ P APPGP P PP E G L
Sbjct: 327 HRLVP--------------AAPPGPGPRPPGAESHG---------------------CLP 351
Query: 1999 GTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIH--FPVTVVSAPGLAPSATPGAP 2056
T P PG E SR P + APS PG P
Sbjct: 352 ATRP-----------------PGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLP 394
Query: 2057 RIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPG----------VVRAGVLGAAGDRARPP 2106
G + S + + RG P PG V G LG + +R P
Sbjct: 395 ------GTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKP 448
Query: 2107 EDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWL 2166
LG P A SLPP P + P L P P AWL
Sbjct: 449 -------------FLGAP----AATPHLSLPPGPS-SPPPPPCPRLLRPPPPP----AWL 486
Query: 2167 PGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQ--------- 2217
G P R A E + L ++F G P PPP+
Sbjct: 487 KG-PACRA-----AREDGE----------ILEELFFGTEGPPRPAPPPLPHREGFLGPPA 530
Query: 2218 ------------PPLPPT--------------ISPTAPTSWTLPPGPLLGVLPVVGVVRP 2251
PP PPT SP P S+ PP + P+ P
Sbjct: 531 SRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSP 590
Query: 2252 APPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAP-PPYKAPRLDEDGEASEDT 2310
A P PPL + + P +PP + ++ S R P +P P P+ E G
Sbjct: 591 AQNPQDPPLVPLTLALPPAPPSSC---HQNTSGSFRRPESPRPRVSFPKTPEVG------ 641
Query: 2311 PQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQER 2355
PG G S+ P GV +L G + P PL+++
Sbjct: 642 ---PGPPPGPLSKAPQPVPP--GVGELPARGPRLFDFPPTPLEDQ 681
Score = 55.5 bits (132), Expect = 7e-07
Identities = 56/169 (33%), Positives = 67/169 (39%), Gaps = 32/169 (18%)
Query: 565 PPI--TTSPPVPQEPAPVPSPPRAPTPPSTPVPLP---EKRRSILREPTFRWTSLTRELP 619
PP+ PPV Q P PP A + PS L ++RR E T L LP
Sbjct: 195 PPVKRAAEPPVVQ-----PVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLP--LP 247
Query: 620 PPP-PAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIY--ESVLTPPPLGAPE- 675
PPP P PPPPP P PPP P ++ P L P S H + E + PP +
Sbjct: 248 PPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLW-STLHGDAWGPERKGSAPPERQEQR 306
Query: 676 --APEPEPPPA-------------DDSPAEPEPRAVGRTNHLSLPRFAP 709
P P P PA +P P PR G +H LP P
Sbjct: 307 HSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRP 355
Score = 54.7 bits (130), Expect = 1e-06
Identities = 135/526 (25%), Positives = 169/526 (32%), Gaps = 118/526 (22%)
Query: 1909 PPRRSRRPSPLAPRPPPS-RWASPPLKTSPQ-LRVPPPTSVVTALTPTSGELAPPGPAPS 1966
P +R+ P + P PP + S SP R S T L P PP P P
Sbjct: 196 PVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPPPP 255
Query: 1967 PPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEE 2026
PPPP P + GL+ + PFQ + G + HG +
Sbjct: 256 PPPPPPPPP-------LPGLAT-----------SPPFQ--LTKPGLWSTLHGDAWGPERK 295
Query: 2027 ESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPS 2086
S+P R P AP+ T P + P G G P
Sbjct: 296 GSAPPERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAA-------------PPGPG--PR 340
Query: 2087 GPGVVRAGVLGAAGDRARPP-EDLPSEIV--DFVLKNLGGPGDGGAGPREESLPPAPPLA 2143
PG G L A RPP DL V + ++ P S PP P
Sbjct: 341 PPGAESHGCLPA----TRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLP-- 394
Query: 2144 NGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPE--------PPKPATSKIILVN 2195
G+ S ++S R PG PG PA E P ++ K L
Sbjct: 395 -GTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQT-PALEVSHHGRLGPSAHSSRKPFLGA 452
Query: 2196 KLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPP--------GPLLGVL--PV 2245
+ + G PPP PP P + P P +W P G +L L
Sbjct: 453 PAATPHLSLP-PGPSSPPP---PPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGT 508
Query: 2246 VGVVRPAPPPPP-------PPLTLVL-----SSGPASPPRQAIRVKRVSTFSGRSPPA-- 2291
G RPAPPP P PP + S P +PP ++ S S PA
Sbjct: 509 EGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGP 568
Query: 2292 ----PPPYKA------PRLDEDGEASEDTPQVP--------------GLGSGGFSRVRMK 2327
PPPY A PR + +D P VP SG F R
Sbjct: 569 VSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESP 628
Query: 2328 TPTVRGVLDLDRPGEPAGEESPGPLQERSPLLPLPEDGPPQVPDGP 2373
P V P P E PGP PL P+ PP V + P
Sbjct: 629 RPRV------SFPKTP--EVGPGP--PPGPLSKAPQPVPPGVGELP 664
Score = 54.3 bits (129), Expect = 2e-06
Identities = 86/343 (25%), Positives = 114/343 (33%), Gaps = 47/343 (13%)
Query: 1785 PWGPREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLD--TDVLVPGAPER-------- 1834
P GP P A + P+P+ P +DPPL T L P P
Sbjct: 565 PAGPVSFPPPPYLARSIDPLPRPPSPAQNP---QDPPLVPLTLALPPAPPSSCHQNTSGS 621
Query: 1835 ----HSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVP---NYSPSRRPLGGVSFGPLPS 1887
SP + P P+ G PPP P S A VP P+R P F P P
Sbjct: 622 FRRPESPRPRVSFPKTPEVGPGPPPGP--LSKAPQPVPPGVGELPARGPRL-FDFPPTPL 678
Query: 1888 PGS----------PSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPP----------PSR 1927
P L + I + D + + + +AP+PP P
Sbjct: 679 EDQFEEPAEFKILPDGLAN-IMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFP 737
Query: 1928 WASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLS 1987
+ P T+P + V T+ T T T E P PA PPPP P +
Sbjct: 738 TDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPPP 797
Query: 1988 AADLDFAASLLGTEPFQEEIV-AAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPG 2046
+ SL Q+ GA S+ GP +++ P S P T +AP
Sbjct: 798 PSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPT-SAAPS 856
Query: 2047 LAPSATPGAPRIEQLDGVDDGTDSEAEAVQQP-RGQGTPPSGP 2088
S P A Q E A ++P G TP P
Sbjct: 857 AQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPP 899
Score = 51.2 bits (121), Expect = 1e-05
Identities = 93/360 (25%), Positives = 124/360 (34%), Gaps = 56/360 (15%)
Query: 439 PPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPT 498
PP+ PP + PV PA S G L+P + R + G P P
Sbjct: 195 PPVKRAAEPPVVQ-------PVPPAALSGPSGEEGLSPGGK-RRRGCNSEQTGLPPGLPL 246
Query: 499 PSTATGGPPEDSPTVAPKSTTFLKNIR-QFIMPVVSARSSRVIKTPRRFMDEDPPKPPKV 557
P PP P P + Q P + + P R PP+ +
Sbjct: 247 PPPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPER-KGSAPPERQEQ 305
Query: 558 EVS-----PVLRPPITTSPP----VP-QEPAPVPSPPRAPTPPSTPVPLPEKRRSILREP 607
S P P T PP VP P P P PP A + P P S LRE
Sbjct: 306 RHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPP--GSDLRES 363
Query: 608 TFRWTSLTRELPPPPPAPPPPPAPSPPPA-PATSSRRPLLLRAPQFTPSEAHLKIYESVL 666
+ + + + P P APS PP P T++ + + S L+ E
Sbjct: 364 RVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTT------SSSSSSSSNTGLRGVE--- 414
Query: 667 TPPPLGAPEAPEPEPP-----------PADDSPAEPEPRAVGRTNHLSLPRF-APVVTTP 714
P G P A + P P+ S +P A T HLSLP + P
Sbjct: 415 --PNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPP 472
Query: 715 VKAEVSPHGAPALSNGPQTQA-----QLLQPLQALQTQLLPQALPPPQPQ----LQPPPS 765
+ P PA GP +A ++L+ L T+ P+ PPP P L PP S
Sbjct: 473 CPRLLRPPPPPAWLKGPACRAAREDGEILEEL-FFGTEGPPRPAPPPLPHREGFLGPPAS 531
Score = 48.5 bits (114), Expect = 9e-05
Identities = 113/477 (23%), Positives = 144/477 (30%), Gaps = 63/477 (13%)
Query: 504 GGPP----EDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEV 559
GGPP + P V P L P S K R E PP + +
Sbjct: 193 GGPPVKRAAEPPVVQPVPPAALSG------PSGEEGLSPGGKRRRGCNSEQTGLPPGLPL 246
Query: 560 SPVLRPPITTSPPVPQEPAP--VPSPPRAPTPPSTPVPL------PEKRRSILREPTFRW 611
P PP PP P P P SPP T P L PE++ S E +
Sbjct: 247 PPPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQR 306
Query: 612 TSLTRELPPPPPA-----------PPPPPAPSPPPAPATSSRRPLLLRAP--QFTPSEAH 658
SL P P PA P PP P P P A S R P S
Sbjct: 307 HSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQ 366
Query: 659 LKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTP---- 714
+S ++P A P PP P + +++ L P P
Sbjct: 367 RSRMDSSVSPAATTACVPYAPSRPPG--LPGTTTSSSSSSSSNTGLRGVEPNPGIPGADH 424
Query: 715 ---VKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQM-P 770
EVS HG S + L P L P PP PPP P+ + P
Sbjct: 425 YQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPP-----PPPCPRLLRP 479
Query: 771 PLEKARIAGVGSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMP-----LSPGGQ 825
P A + G P + +L+ +LF + + +P L P
Sbjct: 480 PPPPAWLKG----PACRAAREDGEILE----ELFFGTEGPPRPAPPPLPHREGFLGPPAS 531
Query: 826 MEEVAGAVKQISDRGPVRSEDESVEAKRERPSGPESPVQGPRIKHVCRHA-AVALGQARA 884
V P + S S P PV P ++ R + + A
Sbjct: 532 RFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPA 591
Query: 885 MVPED---VPRLSALPLRDRQDLATEDTSSASETESVPSRSRRGKVEAAGPGGESEP 938
P+D VP ALP + S ES R K GPG P
Sbjct: 592 QNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGP 648
Score = 35.0 bits (79), Expect = 1.0
Identities = 43/168 (25%), Positives = 60/168 (35%), Gaps = 35/168 (20%)
Query: 130 EDVAPSSLRSALRSQRGRAPRGRGRKHKTT---------PLPPPRLADVAPTPPKTPARK 180
+ V P++L S + G +P G+ R+ + PLPPP L P PP P
Sbjct: 207 QPVPPAAL-SGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPPPPPPPPPPPPPL 265
Query: 181 RGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVV 240
G A +P ++ ST P + + P R++Q
Sbjct: 266 PG----------------LATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQ---- 305
Query: 241 AEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRG 288
++P P P P H G P PGPG PR G S G
Sbjct: 306 ---RHSLPHPYPYPAPAYTAHPPGHRLVPAAP-PGPG-PRPPGAESHG 348
Score = 34.3 bits (77), Expect = 1.7
Identities = 28/90 (31%), Positives = 33/90 (36%), Gaps = 8/90 (8%)
Query: 1047 RGAGAG-----GPREEVVAHPGPEEQDSLLQRKSARRCVKQRPSYDIFEDSDDSEPGGPP 1101
RG GA GP PGP + L SA + P S S GGP
Sbjct: 819 RGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPW 878
Query: 1102 APRRRTPRENELPLPEPEEQSRPRKPTLQP 1131
A RR E P+P P ++P P P
Sbjct: 879 ARERRAGEE---PVPGPMTPTQPPPPLSLP 905
Score = 32.3 bits (72), Expect = 6.5
Identities = 35/146 (23%), Positives = 57/146 (39%), Gaps = 5/146 (3%)
Query: 438 PPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTP 497
PP P+PP PA Q P VP +R+ P S RA+ R+ EG PP
Sbjct: 1046 PPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPGPPGVS-RADMLKLRSLSEG--PPKE 1102
Query: 498 TPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKV 557
D T S + +R + +S ++ V++ R + + +
Sbjct: 1103 LKIRLIKVESGDKETFI-ASEVEERRLRMADL-TISHCAADVVRASRNAKVKGKFRESYL 1160
Query: 558 EVSPVLRPPITTSPPVPQEPAPVPSP 583
+ ++P I T +P+E P+P
Sbjct: 1161 SPAQSVKPKINTEEKLPREKLNPPTP 1186
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 101 bits (251), Expect = 1e-20
Identities = 120/505 (23%), Positives = 175/505 (34%), Gaps = 91/505 (18%)
Query: 311 AKKVKMGQLSLGLESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQKLDDEEEEKKE 370
+KK K ++S +G+G+ +S R V P Q+ + +
Sbjct: 112 SKKTKTQEISRPNSPSEGEGESSDS------RSVNDEGSSDPKDIDQDNRSTSPSIPSPQ 165
Query: 371 EEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPA-PSPPPPLPPPSTSPPPP-- 427
+ E D + +++ A+ PA + P P PP P P P P PS + PP
Sbjct: 166 DNESDSDSSAQQQMLQAQP--PALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQG 223
Query: 428 ----------------------------LCPPPPPPVSPPPLPSPPPPPAQEEQEESPPP 459
L P PP PPP PS P PP Q + P
Sbjct: 224 SPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPS-PHPPLQPLTGSAGQP 282
Query: 460 VVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTT 519
P+ +PPL + +AGP P P P G PP+ S AP T+
Sbjct: 283 SAPS-----HAQPPLHGQGPPGPHSLQAGPLLQHPGPPQP---FGLPPQASQGQAPLGTS 334
Query: 520 FLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAP 579
+ + +++S+ + P R + P PP P ++PP TT P+PQ
Sbjct: 335 PAAAYPHTSLQLPASQSALQSQQPPR----EQPLPPAPLAMPHIKPPPTT--PIPQ---- 384
Query: 580 VPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPP-------PPPAPS 632
+P+P PP P P S+ LPPPP P PP+
Sbjct: 385 LPAPQAHKHPPHLSGPSP--------------FSMNANLPPPPALKPLSSLSTHHPPSAH 430
Query: 633 PPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAP----EAPEPEPPPADDS- 687
PPP +PL +P++ L PPP P P+PP A
Sbjct: 431 PPPLQLMPQSQPL-----PSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPF 485
Query: 688 -PAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQ-PLQALQ 745
P P P S P P + + +++ G +Q +AL
Sbjct: 486 VPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALD 545
Query: 746 TQLLPQALPPPQPQLQPPPSPQQMP 770
P++ PPP P P+ P
Sbjct: 546 DAEEPESPPPPPRSPSPEPTVVDTP 570
Score = 74.7 bits (182), Expect = 1e-12
Identities = 112/460 (24%), Positives = 156/460 (33%), Gaps = 134/460 (29%)
Query: 355 KKQEQKL-DDEEEEKKEEEEKDK-------------EGEEKEERAVAEEMMPAAEKEEAK 400
K+Q +K+ D EE + +K K EGE + R+V +E +++ ++
Sbjct: 94 KRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDE--GSSDPKDID 151
Query: 401 LPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPV 460
+P PSP +S + PP + P +P P A
Sbjct: 152 QDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSA----------- 200
Query: 461 VPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTF 520
PP TP P PTPS AT PP+ SPT +
Sbjct: 201 -----------PPGTPQ--------------LPTPGPTPS-ATAVPPQGSPTAS------ 228
Query: 521 LKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPV-PQEP-A 578
P P+ +PV I +P + PQ P +
Sbjct: 229 -----------------------------QAPNQPQAPTAPVPHTHIQQAPALHPQRPPS 259
Query: 579 PVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPA--------PPPPPA 630
P P P +P PP P+ + S P+ L + PP P + P PP
Sbjct: 260 PHPPPHPSPHPPLQPLTGSAGQPSA---PSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQ 316
Query: 631 PSPPPAPATSSRRPL-LLRAPQFTPSEAHLKIYESVLTP--PPLGAPEAPEP------EP 681
P P A+ + PL A + + L +S L PP P P P +P
Sbjct: 317 PFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKP 376
Query: 682 PPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPL 741
PP P P P+A HLS P +P N L+PL
Sbjct: 377 PPTTPIPQLPAPQAHKHPPHLSGP------------------SPFSMNANLPPPPALKPL 418
Query: 742 QALQTQLLPQALPPPQPQLQP-----PPSPQQMPPLEKAR 776
+L T P A PPP QL P P SP Q P L +++
Sbjct: 419 SSLSTHHPPSAHPPP-LQLMPQSQPLPSSPAQPPGLTQSQ 457
Score = 71.6 bits (174), Expect = 1e-11
Identities = 131/587 (22%), Positives = 171/587 (29%), Gaps = 160/587 (27%)
Query: 89 VQRGRGRGRGRGWGPSRGCVPEEESSDGESDEEEF----------QGFHSDEDVAPSSLR 138
+ R G G V +E SSD + +++ Q SD D +
Sbjct: 120 ISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQM 179
Query: 139 SALRSQRGRAPRGRGRKHKTTPLPPPRLADVAPTPPKTPARKRGEEGTERMVQALTELLR 198
+ +AP G + P P+L PTP T +G ++
Sbjct: 180 LQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGS-------PTASQAPN 232
Query: 199 RAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVP 258
+ QAP AP P RPP P P P P P PP+ P
Sbjct: 233 QPQAPTAPVPHTHIQQAPALHPQRPPS-PHPP-----------------PHPSPHPPLQP 274
Query: 259 VKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGR----GGRGRGRGGGLPFVIKFVSRAKKV 314
+ G + P P GQ G G + G PF
Sbjct: 275 LTGSAG-----QPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPF----------- 318
Query: 315 KMGQLSLGLESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQKLDDEEEEKKEEEEK 374
GL QGQ + G SP L + + ++
Sbjct: 319 -------GLPPQASQGQ--------------APLGTSPAAAYPHTSLQLPASQSALQSQQ 357
Query: 375 DKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLT--PPAPSPPPPLPPPSTSPPPPLCP-- 430
E+ +P A + PPP T P P+P PP S P P
Sbjct: 358 PPR----------EQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNA 407
Query: 431 --PPPPPVSPPPL------PSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAER 482
PPPP + P PS PPP Q + P P PA P LT SQ
Sbjct: 408 NLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQ------PPGLTQSQNLPP 461
Query: 483 EAARAGPEGTSPPTPTPSTA-----TGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSS 537
A P G P P A GGPP +P P ++T
Sbjct: 462 PPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTST------------------ 503
Query: 538 RVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLP 597
P P + PP A S + P V +
Sbjct: 504 -----------------------PPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIK 540
Query: 598 EKRRSILREPTFRWTSLTRELPPPPP-APPPPPAPSPPPAPATSSRR 643
E+ EP E PPPPP +P P P P+ A+ S R
Sbjct: 541 EEALDDAEEP---------ESPPPPPRSPSPEPTVVDTPSHASQSAR 578
Score = 62.8 bits (151), Expect = 5e-09
Identities = 46/153 (30%), Positives = 62/153 (40%), Gaps = 21/153 (13%)
Query: 389 EMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPP---------------PLCPPPP 433
++MP ++ LP P PP + LPPP S PP P P P
Sbjct: 435 QLMPQSQP----LPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGP 490
Query: 434 PPVSPPPLPSPPPPPAQEEQEESPPPVVPATC--SRKRGRPPLTPSQRAEREAARAGPEG 491
PP++PP PS PPA PP A S G P+ + + EA E
Sbjct: 491 PPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEP 550
Query: 492 TSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNI 524
SPP P S + D+P+ A +S F K++
Sbjct: 551 ESPPPPPRSPSPEPTVVDTPSHASQSARFYKHL 583
Score = 58.5 bits (140), Expect = 9e-08
Identities = 126/535 (23%), Positives = 172/535 (32%), Gaps = 142/535 (26%)
Query: 1811 SSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPNY 1870
SS+P + T +P + S + D + A PPA ++ +G P+
Sbjct: 144 SSDPKDIDQDNRSTSPSIPSPQDNES---DSDSSAQQQMLQAQPPALQAPTGVT-PAPSS 199
Query: 1871 SPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPS------------- 1917
+P P LP+PG S T +P G P P + + P+
Sbjct: 200 APPGTP-------QLPTPGPTPSATA-VPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPA 251
Query: 1918 -----PLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPA-------- 1964
P +P PPP PPL+ P++ A P G+ PPGP
Sbjct: 252 LHPQRPPSPHPPPHPSPHPPLQPLTG-SAGQPSAPSHAQPPLHGQ-GPPGPHSLQAGPLL 309
Query: 1965 --PSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGD 2022
P PP P L P + LGT P AA +S P
Sbjct: 310 QHPGPPQPFGLPPQASQ--------------GQAPLGTSP------AAAYPHTSLQLPAS 349
Query: 2023 SSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQG 2082
S +S R P ++ P + P T P++ P+
Sbjct: 350 QSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQL-----------------PAPQAHK 392
Query: 2083 TPP--SGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAP 2140
PP SGP + PP P L +L A P P
Sbjct: 393 HPPHLSGP-----SPFSMNANLPPPPALKP-------LSSLSTHHPPSAHP--------P 432
Query: 2141 PLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQV 2200
PL Q SQ L +SPA P PG + L PA PP L QV
Sbjct: 433 PLQLMPQ-SQPLPSSPAQP-------PGLTQSQNLPPPPASHPP----------TGLHQV 474
Query: 2201 FVKMAGEGEPVPPPVKQPPL----PPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPP 2256
P PP + P + PP PT P++ T P GP PP
Sbjct: 475 --------APQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGP---------GTSAQPPCS 517
Query: 2257 PPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTP 2311
+ +G +S P +++K + P +PPP PR DTP
Sbjct: 518 GAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPP--PPRSPSPEPTVVDTP 570
Score = 51.6 bits (122), Expect = 1e-05
Identities = 52/178 (29%), Positives = 68/178 (38%), Gaps = 17/178 (9%)
Query: 1807 SPAPSSEPPGGEDPPLDTDVLVPGA---PERHSPIQNLDPPLRPDSGSAPPPAPRSFSGA 1863
+PAPSS PPG P L T P A P + SP + P +P + +AP P
Sbjct: 194 TPAPSSAPPG--TPQLPTPGPTPSATAVPPQGSPTAS-QAPNQPQAPTAPVPHTHIQQAP 250
Query: 1864 RI---KVPNYSPSRRPLGGVSFGPLP-SPGSPSSLTHHIPTVGDPDFPAPPRRS-----R 1914
+ + P+ P P PL S G PS+ +H P + P P +
Sbjct: 251 ALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQ 310
Query: 1915 RPSPLAP--RPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPP 1970
P P P PP + PL TSP P + + A PP P PP P
Sbjct: 311 HPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAP 368
Score = 49.7 bits (117), Expect = 4e-05
Identities = 83/373 (22%), Positives = 120/373 (32%), Gaps = 77/373 (20%)
Query: 158 TTPLP----------PPRLADVAP------TPPKTPARKRGEEGTERMVQALTELLRRAQ 201
TTP+P PP L+ +P PP + T A L+
Sbjct: 379 TTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMP 438
Query: 202 APQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVPVKH 261
Q S +P +S+ PP + P Q A P PPP+ P
Sbjct: 439 QSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTC 498
Query: 262 QTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGGLPFVIKFVSRAKKVKMGQLSL 321
+ S GPG P G +S G G G LP V ++K L
Sbjct: 499 PSTSTP-PAGPGTSAQPPCSGAAASGGSIAG---GSSCPLPTV--------QIKEEALDD 546
Query: 322 GLESGQG-----QGQHEESWQDVPQRRVGSGQ----------------------GGSPCW 354
E E + D P S + GS
Sbjct: 547 AEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLA 606
Query: 355 KKQEQKLDD----------EEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPP 404
KK+E+ ++ EE E+++E+EK++E E + ER ++ E +L P
Sbjct: 607 KKREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDP 666
Query: 405 PLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPAT 464
L+ P P PPP+T + PP P P + E + P V+ T
Sbjct: 667 QLSGPGHMRPSFEPPPTTI------------AAVPPYIGPDTPALRTLSEYARPHVMSPT 714
Query: 465 CSRKRGRPPLTPS 477
PL P+
Sbjct: 715 NRNHPFYMPLNPT 727
Score = 47.8 bits (112), Expect = 2e-04
Identities = 127/527 (24%), Positives = 169/527 (32%), Gaps = 121/527 (22%)
Query: 1886 PSPGS-PSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPP 1944
PS G SS + + G D + +R SP P P + S L+ PP
Sbjct: 126 PSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPP 185
Query: 1945 T-SVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPF 2003
T +TP APPG P P G P
Sbjct: 186 ALQAPTGVTPAPSS-APPGTPQLPTP-----------------------------GPTPS 215
Query: 2004 QEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGA-------- 2055
+ G+ +S + + +PT+ H + AP L P P
Sbjct: 216 ATAVPPQGSPTASQ-----APNQPQAPTAPVPH--THIQQAPALHPQRPPSPHPPPHPSP 268
Query: 2056 -PRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIV 2114
P ++ L G + + A GQG P GP ++AG L
Sbjct: 269 HPPLQPLTGSAGQPSAPSHAQPPLHGQGPP--GPHSLQAGPL------------------ 308
Query: 2115 DFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRV 2174
L++ G P G PP A+ Q G + + A P T LP +
Sbjct: 309 ---LQHPGPPQPFGL----------PPQASQGQAPLGTSPAAAYP-HTSLQLPASQSALQ 354
Query: 2175 LSLGPA--PEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQP---------PLPPT 2223
P P PP P I + A + PP + P P PP
Sbjct: 355 SQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPA 414
Query: 2224 ISPTAPTSWTLPPG---PLLGVLPVVGVVRPAPPPPPPPLTLV--LSSGPAS-PPRQAIR 2277
+ P + S PP P L ++P + P+ P PP LT L PAS PP +
Sbjct: 415 LKPLSSLSTHHPPSAHPPPLQLMPQSQPL-PSSPAQPPGLTQSQNLPPPPASHPPTGLHQ 473
Query: 2278 VKRVSTFSGRS--PPAPPPYKAPRLDED-----GEASEDTPQVPGLGSGGFSRV---RMK 2327
V F+ P PPP P G + P G + G S
Sbjct: 474 VAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCP 533
Query: 2328 TPTVRGVLD-LDRPGEPAGEESPGPLQERSPLLPLPEDGPPQVPDGP 2373
PTV+ + LD EP ESP P P P PE P V D P
Sbjct: 534 LPTVQIKEEALDDAEEP---ESPPP----PPRSPSPE---PTVVDTP 570
Score = 41.6 bits (96), Expect = 0.011
Identities = 41/159 (25%), Positives = 55/159 (34%), Gaps = 37/159 (23%)
Query: 1788 PREEPAHLEAAEENQTIVHSPA--------------PSSEPPGG-----EDPPLDTDVLV 1828
P P L+ ++Q + SPA P+S PP G PP V
Sbjct: 427 PSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFV 486
Query: 1829 PGAPERHSPI---QNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPL 1885
PG P +P PP P + + PP + + SG I G S PL
Sbjct: 487 PGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSI------------AGGSSCPL 534
Query: 1886 PSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPP 1924
P+ + +P+ P PP RS P P P
Sbjct: 535 PTVQIKEEA---LDDAEEPESPPPPPRSPSPEPTVVDTP 570
Score = 40.4 bits (93), Expect = 0.024
Identities = 47/168 (27%), Positives = 64/168 (38%), Gaps = 21/168 (12%)
Query: 1808 PAPSSEPPGGED--PPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARI 1865
P P PP PL T P A H+ +Q P + S PP + A +
Sbjct: 315 PQPFGLPPQASQGQAPLGTS---PAAAYPHTSLQL--PASQSALQSQQPPREQPLPPAPL 369
Query: 1866 KVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPA----PPRRSRRP-SPLA 1920
+P+ P P+P +P + H G F PP + +P S L+
Sbjct: 370 AMPHIKPPPTT-------PIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLS 422
Query: 1921 PRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPP 1968
PPS PPL+ PQ + P P+S T + PP PA PP
Sbjct: 423 THHPPSAHP-PPLQLMPQSQ-PLPSSPAQPPGLTQSQNLPPPPASHPP 468
Score = 40.0 bits (92), Expect = 0.031
Identities = 56/196 (28%), Positives = 67/196 (34%), Gaps = 35/196 (17%)
Query: 1810 PSSEPPGGEDP-----PLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPP----PAPRSF 1860
PS PP P PL P AP P + P P S A P P P
Sbjct: 258 PSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQP 317
Query: 1861 SGARIKVPNYSPSRRPLGGVSFGPLPS-----PGSPSSLTHHIPTVGDPDFPAPPRRS-- 1913
G P S + PLG P P S S+L P P PAP
Sbjct: 318 FGLP---PQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHI 374
Query: 1914 ---------RRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPA 1964
+ P+P A + PP S P S +PPP AL P S L+ P
Sbjct: 375 KPPPTTPIPQLPAPQAHKHPPH--LSGPSPFSMNANLPPP----PALKPLS-SLSTHHPP 427
Query: 1965 PSPPPPEDLGPDFEDM 1980
+ PPP L P + +
Sbjct: 428 SAHPPPLQLMPQSQPL 443
Score = 39.7 bits (91), Expect = 0.041
Identities = 53/172 (30%), Positives = 67/172 (38%), Gaps = 31/172 (18%)
Query: 1808 PAPSSEPPGGEDPPLDTDVLVPGAPE--RHSPIQNLDPPLRPDSGSAPPPAPRSFSGARI 1865
PAP + P PP T + AP+ +H P + P ++ PPPA + S
Sbjct: 366 PAPLAMPH--IKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLST 423
Query: 1866 KVPNYSPSRRPLG---GVSFGPLPS-PGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPL-- 1919
P PS P PLPS P P LT + P PP S P+ L
Sbjct: 424 HHP---PSAHPPPLQLMPQSQPLPSSPAQPPGLTQ------SQNLPPPPA-SHPPTGLHQ 473
Query: 1920 -APRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPP 1970
AP+PP +A P + PPT T+ TP P GP S PP
Sbjct: 474 VAPQPP---FAQHPFVPGGPPPITPPTCPSTS-TP------PAGPGTSAQPP 515
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 101 bits (251), Expect = 1e-20
Identities = 120/505 (23%), Positives = 175/505 (34%), Gaps = 91/505 (18%)
Query: 311 AKKVKMGQLSLGLESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQKLDDEEEEKKE 370
+KK K ++S +G+G+ +S R V P Q+ + +
Sbjct: 666 SKKTKTQEISRPNSPSEGEGESSDS------RSVNDEGSSDPKDIDQDNRSTSPSIPSPQ 719
Query: 371 EEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPA-PSPPPPLPPPSTSPPPP-- 427
+ E D + +++ A+ PA + P P PP P P P P PS + PP
Sbjct: 720 DNESDSDSSAQQQMLQAQP--PALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQG 777
Query: 428 ----------------------------LCPPPPPPVSPPPLPSPPPPPAQEEQEESPPP 459
L P PP PPP PS P PP Q + P
Sbjct: 778 SPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPS-PHPPLQPLTGSAGQP 836
Query: 460 VVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTT 519
P+ +PPL + +AGP P P P G PP+ S AP T+
Sbjct: 837 SAPS-----HAQPPLHGQGPPGPHSLQAGPLLQHPGPPQP---FGLPPQASQGQAPLGTS 888
Query: 520 FLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAP 579
+ + +++S+ + P R + P PP P ++PP TT P+PQ
Sbjct: 889 PAAAYPHTSLQLPASQSALQSQQPPR----EQPLPPAPLAMPHIKPPPTT--PIPQ---- 938
Query: 580 VPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPP-------PPPAPS 632
+P+P PP P P S+ LPPPP P PP+
Sbjct: 939 LPAPQAHKHPPHLSGPSP--------------FSMNANLPPPPALKPLSSLSTHHPPSAH 984
Query: 633 PPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAP----EAPEPEPPPADDS- 687
PPP +PL +P++ L PPP P P+PP A
Sbjct: 985 PPPLQLMPQSQPL-----PSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPF 1039
Query: 688 -PAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQ-PLQALQ 745
P P P S P P + + +++ G +Q +AL
Sbjct: 1040 VPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALD 1099
Query: 746 TQLLPQALPPPQPQLQPPPSPQQMP 770
P++ PPP P P+ P
Sbjct: 1100 DAEEPESPPPPPRSPSPEPTVVDTP 1124
Score = 74.7 bits (182), Expect = 1e-12
Identities = 112/460 (24%), Positives = 156/460 (33%), Gaps = 134/460 (29%)
Query: 355 KKQEQKL-DDEEEEKKEEEEKDK-------------EGEEKEERAVAEEMMPAAEKEEAK 400
K+Q +K+ D EE + +K K EGE + R+V +E +++ ++
Sbjct: 648 KRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDE--GSSDPKDID 705
Query: 401 LPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPV 460
+P PSP +S + PP + P +P P A
Sbjct: 706 QDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSA----------- 754
Query: 461 VPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTF 520
PP TP P PTPS AT PP+ SPT +
Sbjct: 755 -----------PPGTPQ--------------LPTPGPTPS-ATAVPPQGSPTAS------ 782
Query: 521 LKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPV-PQEP-A 578
P P+ +PV I +P + PQ P +
Sbjct: 783 -----------------------------QAPNQPQAPTAPVPHTHIQQAPALHPQRPPS 813
Query: 579 PVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPA--------PPPPPA 630
P P P +P PP P+ + S P+ L + PP P + P PP
Sbjct: 814 PHPPPHPSPHPPLQPLTGSAGQPSA---PSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQ 870
Query: 631 PSPPPAPATSSRRPL-LLRAPQFTPSEAHLKIYESVLTP--PPLGAPEAPEP------EP 681
P P A+ + PL A + + L +S L PP P P P +P
Sbjct: 871 PFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKP 930
Query: 682 PPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPL 741
PP P P P+A HLS P +P N L+PL
Sbjct: 931 PPTTPIPQLPAPQAHKHPPHLSGP------------------SPFSMNANLPPPPALKPL 972
Query: 742 QALQTQLLPQALPPPQPQLQP-----PPSPQQMPPLEKAR 776
+L T P A PPP QL P P SP Q P L +++
Sbjct: 973 SSLSTHHPPSAHPPP-LQLMPQSQPLPSSPAQPPGLTQSQ 1011
Score = 71.6 bits (174), Expect = 1e-11
Identities = 131/587 (22%), Positives = 171/587 (29%), Gaps = 160/587 (27%)
Query: 89 VQRGRGRGRGRGWGPSRGCVPEEESSDGESDEEEF----------QGFHSDEDVAPSSLR 138
+ R G G V +E SSD + +++ Q SD D +
Sbjct: 674 ISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQM 733
Query: 139 SALRSQRGRAPRGRGRKHKTTPLPPPRLADVAPTPPKTPARKRGEEGTERMVQALTELLR 198
+ +AP G + P P+L PTP T +G ++
Sbjct: 734 LQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGS-------PTASQAPN 786
Query: 199 RAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVP 258
+ QAP AP P RPP P P P P P PP+ P
Sbjct: 787 QPQAPTAPVPHTHIQQAPALHPQRPPS-PHPP-----------------PHPSPHPPLQP 828
Query: 259 VKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGR----GGRGRGRGGGLPFVIKFVSRAKKV 314
+ G + P P GQ G G + G PF
Sbjct: 829 LTGSAG-----QPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPF----------- 872
Query: 315 KMGQLSLGLESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQKLDDEEEEKKEEEEK 374
GL QGQ + G SP L + + ++
Sbjct: 873 -------GLPPQASQGQ--------------APLGTSPAAAYPHTSLQLPASQSALQSQQ 911
Query: 375 DKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLT--PPAPSPPPPLPPPSTSPPPPLCP-- 430
E+ +P A + PPP T P P+P PP S P P
Sbjct: 912 PPR----------EQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNA 961
Query: 431 --PPPPPVSPPPL------PSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAER 482
PPPP + P PS PPP Q + P P PA P LT SQ
Sbjct: 962 NLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQ------PPGLTQSQNLPP 1015
Query: 483 EAARAGPEGTSPPTPTPSTA-----TGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSS 537
A P G P P A GGPP +P P ++T
Sbjct: 1016 PPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTST------------------ 1057
Query: 538 RVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLP 597
P P + PP A S + P V +
Sbjct: 1058 -----------------------PPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIK 1094
Query: 598 EKRRSILREPTFRWTSLTRELPPPPP-APPPPPAPSPPPAPATSSRR 643
E+ EP E PPPPP +P P P P+ A+ S R
Sbjct: 1095 EEALDDAEEP---------ESPPPPPRSPSPEPTVVDTPSHASQSAR 1132
Score = 62.8 bits (151), Expect = 5e-09
Identities = 46/153 (30%), Positives = 62/153 (40%), Gaps = 21/153 (13%)
Query: 389 EMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPP---------------PLCPPPP 433
++MP ++ LP P PP + LPPP S PP P P P
Sbjct: 989 QLMPQSQP----LPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGP 1044
Query: 434 PPVSPPPLPSPPPPPAQEEQEESPPPVVPATC--SRKRGRPPLTPSQRAEREAARAGPEG 491
PP++PP PS PPA PP A S G P+ + + EA E
Sbjct: 1045 PPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEP 1104
Query: 492 TSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNI 524
SPP P S + D+P+ A +S F K++
Sbjct: 1105 ESPPPPPRSPSPEPTVVDTPSHASQSARFYKHL 1137
Score = 61.2 bits (147), Expect = 1e-08
Identities = 108/470 (22%), Positives = 151/470 (32%), Gaps = 135/470 (28%)
Query: 430 PPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGP 489
PP PV PPP P +E+++ R RG + R+ R+ A P
Sbjct: 543 PPIEKPVDPPPFMFKP----VKEEDDGLSGKHSMRTRRSRGS---MSTLRSGRKKQPASP 595
Query: 490 EGTSPP---------TPTPSTATGGPPEDSPTVAPKS--------TTFLKNIRQFIMPVV 532
+G + P +PS A+ + KS ++ LK+ ++ V
Sbjct: 596 DGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVA 655
Query: 533 S------ARSSRVIKT------------------PRRFMDEDPPKPPKVE-----VSPVL 563
S SS+ KT R DE P ++ SP +
Sbjct: 656 SDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSI 715
Query: 564 RPP---------------ITTSPPVPQEPAPV--------PSPPRAPTPPSTP--VPLPE 598
P + PP Q P V P P+ PTP TP +P
Sbjct: 716 PSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPP 775
Query: 599 KRRSILREPTFRWTSLTRELP--------------PPPPAPPPPPAPSPPPAPATSS--- 641
+ + + + T +P PP P PPP P+P PP P T S
Sbjct: 776 QGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQ 835
Query: 642 -------RRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPR 694
+ PL + P S + + P P G P P SPA P
Sbjct: 836 PSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPH 895
Query: 695 AVGR--------------------TNHLSLPRFAPVVTTPVKAEVSP--HGAPALSNGPQ 732
+ L++P P TTP+ +P H P +GP
Sbjct: 896 TSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPS 955
Query: 733 TQAQ--------LLQPLQALQTQLLPQALPPP---QPQLQPPPSPQQMPP 771
+ L+PL +L T P A PPP PQ QP PS PP
Sbjct: 956 PFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPP 1005
Score = 58.5 bits (140), Expect = 9e-08
Identities = 126/535 (23%), Positives = 172/535 (32%), Gaps = 142/535 (26%)
Query: 1811 SSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPNY 1870
SS+P + T +P + S + D + A PPA ++ +G P+
Sbjct: 698 SSDPKDIDQDNRSTSPSIPSPQDNES---DSDSSAQQQMLQAQPPALQAPTGVT-PAPSS 753
Query: 1871 SPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPS------------- 1917
+P P LP+PG S T +P G P P + + P+
Sbjct: 754 APPGTP-------QLPTPGPTPSATA-VPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPA 805
Query: 1918 -----PLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPA-------- 1964
P +P PPP PPL+ P++ A P G+ PPGP
Sbjct: 806 LHPQRPPSPHPPPHPSPHPPLQPLTG-SAGQPSAPSHAQPPLHGQ-GPPGPHSLQAGPLL 863
Query: 1965 --PSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGD 2022
P PP P L P + LGT P AA +S P
Sbjct: 864 QHPGPPQPFGLPPQASQ--------------GQAPLGTSP------AAAYPHTSLQLPAS 903
Query: 2023 SSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQG 2082
S +S R P ++ P + P T P++ P+
Sbjct: 904 QSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQL-----------------PAPQAHK 946
Query: 2083 TPP--SGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAP 2140
PP SGP + PP P L +L A P P
Sbjct: 947 HPPHLSGP-----SPFSMNANLPPPPALKP-------LSSLSTHHPPSAHP--------P 986
Query: 2141 PLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQV 2200
PL Q SQ L +SPA P PG + L PA PP L QV
Sbjct: 987 PLQLMPQ-SQPLPSSPAQP-------PGLTQSQNLPPPPASHPP----------TGLHQV 1028
Query: 2201 FVKMAGEGEPVPPPVKQPPL----PPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPP 2256
P PP + P + PP PT P++ T P GP PP
Sbjct: 1029 --------APQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGP---------GTSAQPPCS 1071
Query: 2257 PPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTP 2311
+ +G +S P +++K + P +PPP PR DTP
Sbjct: 1072 GAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPP--PPRSPSPEPTVVDTP 1124
Score = 51.6 bits (122), Expect = 1e-05
Identities = 52/178 (29%), Positives = 68/178 (38%), Gaps = 17/178 (9%)
Query: 1807 SPAPSSEPPGGEDPPLDTDVLVPGA---PERHSPIQNLDPPLRPDSGSAPPPAPRSFSGA 1863
+PAPSS PPG P L T P A P + SP + P +P + +AP P
Sbjct: 748 TPAPSSAPPG--TPQLPTPGPTPSATAVPPQGSPTAS-QAPNQPQAPTAPVPHTHIQQAP 804
Query: 1864 RI---KVPNYSPSRRPLGGVSFGPLP-SPGSPSSLTHHIPTVGDPDFPAPPRRS-----R 1914
+ + P+ P P PL S G PS+ +H P + P P +
Sbjct: 805 ALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQ 864
Query: 1915 RPSPLAP--RPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPP 1970
P P P PP + PL TSP P + + A PP P PP P
Sbjct: 865 HPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAP 922
Score = 49.7 bits (117), Expect = 4e-05
Identities = 83/373 (22%), Positives = 120/373 (32%), Gaps = 77/373 (20%)
Query: 158 TTPLP----------PPRLADVAP------TPPKTPARKRGEEGTERMVQALTELLRRAQ 201
TTP+P PP L+ +P PP + T A L+
Sbjct: 933 TTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMP 992
Query: 202 APQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVPVKH 261
Q S +P +S+ PP + P Q A P PPP+ P
Sbjct: 993 QSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTC 1052
Query: 262 QTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGGLPFVIKFVSRAKKVKMGQLSL 321
+ S GPG P G +S G G G LP V ++K L
Sbjct: 1053 PSTSTP-PAGPGTSAQPPCSGAAASGGSIAG---GSSCPLPTV--------QIKEEALDD 1100
Query: 322 GLESGQG-----QGQHEESWQDVPQRRVGSGQ----------------------GGSPCW 354
E E + D P S + GS
Sbjct: 1101 AEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLA 1160
Query: 355 KKQEQKLDD----------EEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPP 404
KK+E+ ++ EE E+++E+EK++E E + ER ++ E +L P
Sbjct: 1161 KKREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDP 1220
Query: 405 PLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPAT 464
L+ P P PPP+T + PP P P + E + P V+ T
Sbjct: 1221 QLSGPGHMRPSFEPPPTTI------------AAVPPYIGPDTPALRTLSEYARPHVMSPT 1268
Query: 465 CSRKRGRPPLTPS 477
PL P+
Sbjct: 1269 NRNHPFYMPLNPT 1281
Score = 47.8 bits (112), Expect = 2e-04
Identities = 127/527 (24%), Positives = 169/527 (32%), Gaps = 121/527 (22%)
Query: 1886 PSPGS-PSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPP 1944
PS G SS + + G D + +R SP P P + S L+ PP
Sbjct: 680 PSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPP 739
Query: 1945 T-SVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPF 2003
T +TP APPG P P G P
Sbjct: 740 ALQAPTGVTPAPSS-APPGTPQLPTP-----------------------------GPTPS 769
Query: 2004 QEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGA-------- 2055
+ G+ +S + + +PT+ H + AP L P P
Sbjct: 770 ATAVPPQGSPTASQ-----APNQPQAPTAPVPH--THIQQAPALHPQRPPSPHPPPHPSP 822
Query: 2056 -PRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIV 2114
P ++ L G + + A GQG P GP ++AG L
Sbjct: 823 HPPLQPLTGSAGQPSAPSHAQPPLHGQGPP--GPHSLQAGPL------------------ 862
Query: 2115 DFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRV 2174
L++ G P G PP A+ Q G + + A P T LP +
Sbjct: 863 ---LQHPGPPQPFGL----------PPQASQGQAPLGTSPAAAYP-HTSLQLPASQSALQ 908
Query: 2175 LSLGPA--PEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQP---------PLPPT 2223
P P PP P I + A + PP + P P PP
Sbjct: 909 SQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPA 968
Query: 2224 ISPTAPTSWTLPPG---PLLGVLPVVGVVRPAPPPPPPPLTLV--LSSGPAS-PPRQAIR 2277
+ P + S PP P L ++P + P+ P PP LT L PAS PP +
Sbjct: 969 LKPLSSLSTHHPPSAHPPPLQLMPQSQPL-PSSPAQPPGLTQSQNLPPPPASHPPTGLHQ 1027
Query: 2278 VKRVSTFSGRS--PPAPPPYKAPRLDED-----GEASEDTPQVPGLGSGGFSRV---RMK 2327
V F+ P PPP P G + P G + G S
Sbjct: 1028 VAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCP 1087
Query: 2328 TPTVRGVLD-LDRPGEPAGEESPGPLQERSPLLPLPEDGPPQVPDGP 2373
PTV+ + LD EP ESP P P P PE P V D P
Sbjct: 1088 LPTVQIKEEALDDAEEP---ESPPP----PPRSPSPE---PTVVDTP 1124
Score = 41.6 bits (96), Expect = 0.011
Identities = 41/159 (25%), Positives = 55/159 (34%), Gaps = 37/159 (23%)
Query: 1788 PREEPAHLEAAEENQTIVHSPA--------------PSSEPPGG-----EDPPLDTDVLV 1828
P P L+ ++Q + SPA P+S PP G PP V
Sbjct: 981 PSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFV 1040
Query: 1829 PGAPERHSPI---QNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPL 1885
PG P +P PP P + + PP + + SG I G S PL
Sbjct: 1041 PGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSI------------AGGSSCPL 1088
Query: 1886 PSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPP 1924
P+ + +P+ P PP RS P P P
Sbjct: 1089 PTVQIKEEA---LDDAEEPESPPPPPRSPSPEPTVVDTP 1124
Score = 40.4 bits (93), Expect = 0.024
Identities = 47/168 (27%), Positives = 64/168 (38%), Gaps = 21/168 (12%)
Query: 1808 PAPSSEPPGGED--PPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARI 1865
P P PP PL T P A H+ +Q P + S PP + A +
Sbjct: 869 PQPFGLPPQASQGQAPLGTS---PAAAYPHTSLQL--PASQSALQSQQPPREQPLPPAPL 923
Query: 1866 KVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPA----PPRRSRRP-SPLA 1920
+P+ P P+P +P + H G F PP + +P S L+
Sbjct: 924 AMPHIKPPPTT-------PIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLS 976
Query: 1921 PRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPP 1968
PPS PPL+ PQ + P P+S T + PP PA PP
Sbjct: 977 THHPPSAHP-PPLQLMPQSQ-PLPSSPAQPPGLTQSQNLPPPPASHPP 1022
Score = 40.0 bits (92), Expect = 0.031
Identities = 56/196 (28%), Positives = 67/196 (34%), Gaps = 35/196 (17%)
Query: 1810 PSSEPPGGEDP-----PLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPP----PAPRSF 1860
PS PP P PL P AP P + P P S A P P P
Sbjct: 812 PSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQP 871
Query: 1861 SGARIKVPNYSPSRRPLGGVSFGPLPS-----PGSPSSLTHHIPTVGDPDFPAPPRRS-- 1913
G P S + PLG P P S S+L P P PAP
Sbjct: 872 FGLP---PQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHI 928
Query: 1914 ---------RRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPA 1964
+ P+P A + PP S P S +PPP AL P S L+ P
Sbjct: 929 KPPPTTPIPQLPAPQAHKHPPH--LSGPSPFSMNANLPPP----PALKPLS-SLSTHHPP 981
Query: 1965 PSPPPPEDLGPDFEDM 1980
+ PPP L P + +
Sbjct: 982 SAHPPPLQLMPQSQPL 997
Score = 39.7 bits (91), Expect = 0.041
Identities = 53/172 (30%), Positives = 67/172 (38%), Gaps = 31/172 (18%)
Query: 1808 PAPSSEPPGGEDPPLDTDVLVPGAPE--RHSPIQNLDPPLRPDSGSAPPPAPRSFSGARI 1865
PAP + P PP T + AP+ +H P + P ++ PPPA + S
Sbjct: 920 PAPLAMPH--IKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLST 977
Query: 1866 KVPNYSPSRRPLG---GVSFGPLPS-PGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPL-- 1919
P PS P PLPS P P LT + P PP S P+ L
Sbjct: 978 HHP---PSAHPPPLQLMPQSQPLPSSPAQPPGLTQ------SQNLPPPPA-SHPPTGLHQ 1027
Query: 1920 -APRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPP 1970
AP+PP +A P + PPT T+ TP P GP S PP
Sbjct: 1028 VAPQPP---FAQHPFVPGGPPPITPPTCPSTS-TP------PAGPGTSAQPP 1069
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 101 bits (251), Expect = 1e-20
Identities = 120/505 (23%), Positives = 175/505 (34%), Gaps = 91/505 (18%)
Query: 311 AKKVKMGQLSLGLESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQKLDDEEEEKKE 370
+KK K ++S +G+G+ +S R V P Q+ + +
Sbjct: 666 SKKTKTQEISRPNSPSEGEGESSDS------RSVNDEGSSDPKDIDQDNRSTSPSIPSPQ 719
Query: 371 EEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPA-PSPPPPLPPPSTSPPPP-- 427
+ E D + +++ A+ PA + P P PP P P P P PS + PP
Sbjct: 720 DNESDSDSSAQQQMLQAQP--PALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQG 777
Query: 428 ----------------------------LCPPPPPPVSPPPLPSPPPPPAQEEQEESPPP 459
L P PP PPP PS P PP Q + P
Sbjct: 778 SPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPS-PHPPLQPLTGSAGQP 836
Query: 460 VVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTT 519
P+ +PPL + +AGP P P P G PP+ S AP T+
Sbjct: 837 SAPS-----HAQPPLHGQGPPGPHSLQAGPLLQHPGPPQP---FGLPPQASQGQAPLGTS 888
Query: 520 FLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAP 579
+ + +++S+ + P R + P PP P ++PP TT P+PQ
Sbjct: 889 PAAAYPHTSLQLPASQSALQSQQPPR----EQPLPPAPLAMPHIKPPPTT--PIPQ---- 938
Query: 580 VPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPP-------PPPAPS 632
+P+P PP P P S+ LPPPP P PP+
Sbjct: 939 LPAPQAHKHPPHLSGPSP--------------FSMNANLPPPPALKPLSSLSTHHPPSAH 984
Query: 633 PPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAP----EAPEPEPPPADDS- 687
PPP +PL +P++ L PPP P P+PP A
Sbjct: 985 PPPLQLMPQSQPL-----PSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPF 1039
Query: 688 -PAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQ-PLQALQ 745
P P P S P P + + +++ G +Q +AL
Sbjct: 1040 VPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALD 1099
Query: 746 TQLLPQALPPPQPQLQPPPSPQQMP 770
P++ PPP P P+ P
Sbjct: 1100 DAEEPESPPPPPRSPSPEPTVVDTP 1124
Score = 74.7 bits (182), Expect = 1e-12
Identities = 112/460 (24%), Positives = 156/460 (33%), Gaps = 134/460 (29%)
Query: 355 KKQEQKL-DDEEEEKKEEEEKDK-------------EGEEKEERAVAEEMMPAAEKEEAK 400
K+Q +K+ D EE + +K K EGE + R+V +E +++ ++
Sbjct: 648 KRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDE--GSSDPKDID 705
Query: 401 LPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPV 460
+P PSP +S + PP + P +P P A
Sbjct: 706 QDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSA----------- 754
Query: 461 VPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTF 520
PP TP P PTPS AT PP+ SPT +
Sbjct: 755 -----------PPGTPQ--------------LPTPGPTPS-ATAVPPQGSPTAS------ 782
Query: 521 LKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPV-PQEP-A 578
P P+ +PV I +P + PQ P +
Sbjct: 783 -----------------------------QAPNQPQAPTAPVPHTHIQQAPALHPQRPPS 813
Query: 579 PVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPA--------PPPPPA 630
P P P +P PP P+ + S P+ L + PP P + P PP
Sbjct: 814 PHPPPHPSPHPPLQPLTGSAGQPSA---PSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQ 870
Query: 631 PSPPPAPATSSRRPL-LLRAPQFTPSEAHLKIYESVLTP--PPLGAPEAPEP------EP 681
P P A+ + PL A + + L +S L PP P P P +P
Sbjct: 871 PFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKP 930
Query: 682 PPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPL 741
PP P P P+A HLS P +P N L+PL
Sbjct: 931 PPTTPIPQLPAPQAHKHPPHLSGP------------------SPFSMNANLPPPPALKPL 972
Query: 742 QALQTQLLPQALPPPQPQLQP-----PPSPQQMPPLEKAR 776
+L T P A PPP QL P P SP Q P L +++
Sbjct: 973 SSLSTHHPPSAHPPP-LQLMPQSQPLPSSPAQPPGLTQSQ 1011
Score = 71.6 bits (174), Expect = 1e-11
Identities = 131/587 (22%), Positives = 171/587 (29%), Gaps = 160/587 (27%)
Query: 89 VQRGRGRGRGRGWGPSRGCVPEEESSDGESDEEEF----------QGFHSDEDVAPSSLR 138
+ R G G V +E SSD + +++ Q SD D +
Sbjct: 674 ISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQM 733
Query: 139 SALRSQRGRAPRGRGRKHKTTPLPPPRLADVAPTPPKTPARKRGEEGTERMVQALTELLR 198
+ +AP G + P P+L PTP T +G ++
Sbjct: 734 LQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGS-------PTASQAPN 786
Query: 199 RAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVP 258
+ QAP AP P RPP P P P P P PP+ P
Sbjct: 787 QPQAPTAPVPHTHIQQAPALHPQRPPS-PHPP-----------------PHPSPHPPLQP 828
Query: 259 VKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGR----GGRGRGRGGGLPFVIKFVSRAKKV 314
+ G + P P GQ G G + G PF
Sbjct: 829 LTGSAG-----QPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPF----------- 872
Query: 315 KMGQLSLGLESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQKLDDEEEEKKEEEEK 374
GL QGQ + G SP L + + ++
Sbjct: 873 -------GLPPQASQGQ--------------APLGTSPAAAYPHTSLQLPASQSALQSQQ 911
Query: 375 DKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLT--PPAPSPPPPLPPPSTSPPPPLCP-- 430
E+ +P A + PPP T P P+P PP S P P
Sbjct: 912 PPR----------EQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNA 961
Query: 431 --PPPPPVSPPPL------PSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAER 482
PPPP + P PS PPP Q + P P PA P LT SQ
Sbjct: 962 NLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQ------PPGLTQSQNLPP 1015
Query: 483 EAARAGPEGTSPPTPTPSTA-----TGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSS 537
A P G P P A GGPP +P P ++T
Sbjct: 1016 PPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTST------------------ 1057
Query: 538 RVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLP 597
P P + PP A S + P V +
Sbjct: 1058 -----------------------PPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIK 1094
Query: 598 EKRRSILREPTFRWTSLTRELPPPPP-APPPPPAPSPPPAPATSSRR 643
E+ EP E PPPPP +P P P P+ A+ S R
Sbjct: 1095 EEALDDAEEP---------ESPPPPPRSPSPEPTVVDTPSHASQSAR 1132
Score = 62.8 bits (151), Expect = 5e-09
Identities = 46/153 (30%), Positives = 62/153 (40%), Gaps = 21/153 (13%)
Query: 389 EMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPP---------------PLCPPPP 433
++MP ++ LP P PP + LPPP S PP P P P
Sbjct: 989 QLMPQSQP----LPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGP 1044
Query: 434 PPVSPPPLPSPPPPPAQEEQEESPPPVVPATC--SRKRGRPPLTPSQRAEREAARAGPEG 491
PP++PP PS PPA PP A S G P+ + + EA E
Sbjct: 1045 PPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEP 1104
Query: 492 TSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNI 524
SPP P S + D+P+ A +S F K++
Sbjct: 1105 ESPPPPPRSPSPEPTVVDTPSHASQSARFYKHL 1137
Score = 61.2 bits (147), Expect = 1e-08
Identities = 108/470 (22%), Positives = 151/470 (32%), Gaps = 135/470 (28%)
Query: 430 PPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGP 489
PP PV PPP P +E+++ R RG + R+ R+ A P
Sbjct: 543 PPIEKPVDPPPFMFKP----VKEEDDGLSGKHSMRTRRSRGS---MSTLRSGRKKQPASP 595
Query: 490 EGTSPP---------TPTPSTATGGPPEDSPTVAPKS--------TTFLKNIRQFIMPVV 532
+G + P +PS A+ + KS ++ LK+ ++ V
Sbjct: 596 DGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVA 655
Query: 533 S------ARSSRVIKT------------------PRRFMDEDPPKPPKVE-----VSPVL 563
S SS+ KT R DE P ++ SP +
Sbjct: 656 SDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSI 715
Query: 564 RPP---------------ITTSPPVPQEPAPV--------PSPPRAPTPPSTP--VPLPE 598
P + PP Q P V P P+ PTP TP +P
Sbjct: 716 PSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPP 775
Query: 599 KRRSILREPTFRWTSLTRELP--------------PPPPAPPPPPAPSPPPAPATSS--- 641
+ + + + T +P PP P PPP P+P PP P T S
Sbjct: 776 QGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQ 835
Query: 642 -------RRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPR 694
+ PL + P S + + P P G P P SPA P
Sbjct: 836 PSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPH 895
Query: 695 AVGR--------------------TNHLSLPRFAPVVTTPVKAEVSP--HGAPALSNGPQ 732
+ L++P P TTP+ +P H P +GP
Sbjct: 896 TSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPS 955
Query: 733 TQAQ--------LLQPLQALQTQLLPQALPPP---QPQLQPPPSPQQMPP 771
+ L+PL +L T P A PPP PQ QP PS PP
Sbjct: 956 PFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPP 1005
Score = 58.5 bits (140), Expect = 9e-08
Identities = 126/535 (23%), Positives = 172/535 (32%), Gaps = 142/535 (26%)
Query: 1811 SSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPNY 1870
SS+P + T +P + S + D + A PPA ++ +G P+
Sbjct: 698 SSDPKDIDQDNRSTSPSIPSPQDNES---DSDSSAQQQMLQAQPPALQAPTGVT-PAPSS 753
Query: 1871 SPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPS------------- 1917
+P P LP+PG S T +P G P P + + P+
Sbjct: 754 APPGTP-------QLPTPGPTPSATA-VPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPA 805
Query: 1918 -----PLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPA-------- 1964
P +P PPP PPL+ P++ A P G+ PPGP
Sbjct: 806 LHPQRPPSPHPPPHPSPHPPLQPLTG-SAGQPSAPSHAQPPLHGQ-GPPGPHSLQAGPLL 863
Query: 1965 --PSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGD 2022
P PP P L P + LGT P AA +S P
Sbjct: 864 QHPGPPQPFGLPPQASQ--------------GQAPLGTSP------AAAYPHTSLQLPAS 903
Query: 2023 SSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQG 2082
S +S R P ++ P + P T P++ P+
Sbjct: 904 QSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQL-----------------PAPQAHK 946
Query: 2083 TPP--SGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAP 2140
PP SGP + PP P L +L A P P
Sbjct: 947 HPPHLSGP-----SPFSMNANLPPPPALKP-------LSSLSTHHPPSAHP--------P 986
Query: 2141 PLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQV 2200
PL Q SQ L +SPA P PG + L PA PP L QV
Sbjct: 987 PLQLMPQ-SQPLPSSPAQP-------PGLTQSQNLPPPPASHPP----------TGLHQV 1028
Query: 2201 FVKMAGEGEPVPPPVKQPPL----PPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPP 2256
P PP + P + PP PT P++ T P GP PP
Sbjct: 1029 --------APQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGP---------GTSAQPPCS 1071
Query: 2257 PPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTP 2311
+ +G +S P +++K + P +PPP PR DTP
Sbjct: 1072 GAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPP--PPRSPSPEPTVVDTP 1124
Score = 51.6 bits (122), Expect = 1e-05
Identities = 52/178 (29%), Positives = 68/178 (38%), Gaps = 17/178 (9%)
Query: 1807 SPAPSSEPPGGEDPPLDTDVLVPGA---PERHSPIQNLDPPLRPDSGSAPPPAPRSFSGA 1863
+PAPSS PPG P L T P A P + SP + P +P + +AP P
Sbjct: 748 TPAPSSAPPG--TPQLPTPGPTPSATAVPPQGSPTAS-QAPNQPQAPTAPVPHTHIQQAP 804
Query: 1864 RI---KVPNYSPSRRPLGGVSFGPLP-SPGSPSSLTHHIPTVGDPDFPAPPRRS-----R 1914
+ + P+ P P PL S G PS+ +H P + P P +
Sbjct: 805 ALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQ 864
Query: 1915 RPSPLAP--RPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPP 1970
P P P PP + PL TSP P + + A PP P PP P
Sbjct: 865 HPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAP 922
Score = 49.7 bits (117), Expect = 4e-05
Identities = 83/373 (22%), Positives = 120/373 (32%), Gaps = 77/373 (20%)
Query: 158 TTPLP----------PPRLADVAP------TPPKTPARKRGEEGTERMVQALTELLRRAQ 201
TTP+P PP L+ +P PP + T A L+
Sbjct: 933 TTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMP 992
Query: 202 APQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVPVKH 261
Q S +P +S+ PP + P Q A P PPP+ P
Sbjct: 993 QSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTC 1052
Query: 262 QTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGGLPFVIKFVSRAKKVKMGQLSL 321
+ S GPG P G +S G G G LP V ++K L
Sbjct: 1053 PSTSTP-PAGPGTSAQPPCSGAAASGGSIAG---GSSCPLPTV--------QIKEEALDD 1100
Query: 322 GLESGQG-----QGQHEESWQDVPQRRVGSGQ----------------------GGSPCW 354
E E + D P S + GS
Sbjct: 1101 AEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLA 1160
Query: 355 KKQEQKLDD----------EEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPP 404
KK+E+ ++ EE E+++E+EK++E E + ER ++ E +L P
Sbjct: 1161 KKREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDP 1220
Query: 405 PLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPAT 464
L+ P P PPP+T + PP P P + E + P V+ T
Sbjct: 1221 QLSGPGHMRPSFEPPPTTI------------AAVPPYIGPDTPALRTLSEYARPHVMSPT 1268
Query: 465 CSRKRGRPPLTPS 477
PL P+
Sbjct: 1269 NRNHPFYMPLNPT 1281
Score = 47.8 bits (112), Expect = 2e-04
Identities = 127/527 (24%), Positives = 169/527 (32%), Gaps = 121/527 (22%)
Query: 1886 PSPGS-PSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPP 1944
PS G SS + + G D + +R SP P P + S L+ PP
Sbjct: 680 PSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPP 739
Query: 1945 T-SVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPF 2003
T +TP APPG P P G P
Sbjct: 740 ALQAPTGVTPAPSS-APPGTPQLPTP-----------------------------GPTPS 769
Query: 2004 QEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGA-------- 2055
+ G+ +S + + +PT+ H + AP L P P
Sbjct: 770 ATAVPPQGSPTASQ-----APNQPQAPTAPVPH--THIQQAPALHPQRPPSPHPPPHPSP 822
Query: 2056 -PRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIV 2114
P ++ L G + + A GQG P GP ++AG L
Sbjct: 823 HPPLQPLTGSAGQPSAPSHAQPPLHGQGPP--GPHSLQAGPL------------------ 862
Query: 2115 DFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRV 2174
L++ G P G PP A+ Q G + + A P T LP +
Sbjct: 863 ---LQHPGPPQPFGL----------PPQASQGQAPLGTSPAAAYP-HTSLQLPASQSALQ 908
Query: 2175 LSLGPA--PEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQP---------PLPPT 2223
P P PP P I + A + PP + P P PP
Sbjct: 909 SQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPA 968
Query: 2224 ISPTAPTSWTLPPG---PLLGVLPVVGVVRPAPPPPPPPLTLV--LSSGPAS-PPRQAIR 2277
+ P + S PP P L ++P + P+ P PP LT L PAS PP +
Sbjct: 969 LKPLSSLSTHHPPSAHPPPLQLMPQSQPL-PSSPAQPPGLTQSQNLPPPPASHPPTGLHQ 1027
Query: 2278 VKRVSTFSGRS--PPAPPPYKAPRLDED-----GEASEDTPQVPGLGSGGFSRV---RMK 2327
V F+ P PPP P G + P G + G S
Sbjct: 1028 VAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCP 1087
Query: 2328 TPTVRGVLD-LDRPGEPAGEESPGPLQERSPLLPLPEDGPPQVPDGP 2373
PTV+ + LD EP ESP P P P PE P V D P
Sbjct: 1088 LPTVQIKEEALDDAEEP---ESPPP----PPRSPSPE---PTVVDTP 1124
Score = 41.6 bits (96), Expect = 0.011
Identities = 41/159 (25%), Positives = 55/159 (34%), Gaps = 37/159 (23%)
Query: 1788 PREEPAHLEAAEENQTIVHSPA--------------PSSEPPGG-----EDPPLDTDVLV 1828
P P L+ ++Q + SPA P+S PP G PP V
Sbjct: 981 PSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFV 1040
Query: 1829 PGAPERHSPI---QNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPL 1885
PG P +P PP P + + PP + + SG I G S PL
Sbjct: 1041 PGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSI------------AGGSSCPL 1088
Query: 1886 PSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPP 1924
P+ + +P+ P PP RS P P P
Sbjct: 1089 PTVQIKEEA---LDDAEEPESPPPPPRSPSPEPTVVDTP 1124
Score = 40.4 bits (93), Expect = 0.024
Identities = 47/168 (27%), Positives = 64/168 (38%), Gaps = 21/168 (12%)
Query: 1808 PAPSSEPPGGED--PPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARI 1865
P P PP PL T P A H+ +Q P + S PP + A +
Sbjct: 869 PQPFGLPPQASQGQAPLGTS---PAAAYPHTSLQL--PASQSALQSQQPPREQPLPPAPL 923
Query: 1866 KVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPA----PPRRSRRP-SPLA 1920
+P+ P P+P +P + H G F PP + +P S L+
Sbjct: 924 AMPHIKPPPTT-------PIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLS 976
Query: 1921 PRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPP 1968
PPS PPL+ PQ + P P+S T + PP PA PP
Sbjct: 977 THHPPSAHP-PPLQLMPQSQ-PLPSSPAQPPGLTQSQNLPPPPASHPP 1022
Score = 40.0 bits (92), Expect = 0.031
Identities = 56/196 (28%), Positives = 67/196 (34%), Gaps = 35/196 (17%)
Query: 1810 PSSEPPGGEDP-----PLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPP----PAPRSF 1860
PS PP P PL P AP P + P P S A P P P
Sbjct: 812 PSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQP 871
Query: 1861 SGARIKVPNYSPSRRPLGGVSFGPLPS-----PGSPSSLTHHIPTVGDPDFPAPPRRS-- 1913
G P S + PLG P P S S+L P P PAP
Sbjct: 872 FGLP---PQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHI 928
Query: 1914 ---------RRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPA 1964
+ P+P A + PP S P S +PPP AL P S L+ P
Sbjct: 929 KPPPTTPIPQLPAPQAHKHPPH--LSGPSPFSMNANLPPP----PALKPLS-SLSTHHPP 981
Query: 1965 PSPPPPEDLGPDFEDM 1980
+ PPP L P + +
Sbjct: 982 SAHPPPLQLMPQSQPL 997
Score = 39.7 bits (91), Expect = 0.041
Identities = 53/172 (30%), Positives = 67/172 (38%), Gaps = 31/172 (18%)
Query: 1808 PAPSSEPPGGEDPPLDTDVLVPGAPE--RHSPIQNLDPPLRPDSGSAPPPAPRSFSGARI 1865
PAP + P PP T + AP+ +H P + P ++ PPPA + S
Sbjct: 920 PAPLAMPH--IKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLST 977
Query: 1866 KVPNYSPSRRPLG---GVSFGPLPS-PGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPL-- 1919
P PS P PLPS P P LT + P PP S P+ L
Sbjct: 978 HHP---PSAHPPPLQLMPQSQPLPSSPAQPPGLTQ------SQNLPPPPA-SHPPTGLHQ 1027
Query: 1920 -APRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPP 1970
AP+PP +A P + PPT T+ TP P GP S PP
Sbjct: 1028 VAPQPP---FAQHPFVPGGPPPITPPTCPSTS-TP------PAGPGTSAQPP 1069
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 99.0 bits (245), Expect = 6e-20
Identities = 120/406 (29%), Positives = 144/406 (35%), Gaps = 92/406 (22%)
Query: 403 PPPLTPPAPSPP----PPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPP 458
PP L P P P LPPPST P P PP PPPL P P P Q +P
Sbjct: 692 PPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLP----QVLAPQ 747
Query: 459 PVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKST 518
PVVP P+ P PP P++ G P + P P++
Sbjct: 748 PVVPL--------QPVPPH---------------LPPYLAPASQVGAPAQLKPLQMPQA- 783
Query: 519 TFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPA 578
P + + + PP+ P + V PPIT + P
Sbjct: 784 ------------------------PLQPLAQVPPQMPPIPVV----PPITPLAGIDGLPP 815
Query: 579 PVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPA--------PPPPPA 630
+P P A P PVP P+ P SL LPP PA P PP A
Sbjct: 816 ALPDLPTATVP---PVPPPQ-----YFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGA 867
Query: 631 PSPPP----APATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPA-D 685
P P P + PLL AP P A L I+ +V P G P P P A
Sbjct: 868 PLAMPCRTIVPNAPATIPLLAVAP---PGVAALSIHSAVAQLP--GQPVYPAAFPQMAPT 922
Query: 686 DSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQAL- 744
D P P P P T P + + P P L P Q +P Q +
Sbjct: 923 DVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQ--PTLPPQPVLPPQPTRPPQPVL 980
Query: 745 --QTQLLPQALPPPQPQLQPPPSP-QQMPPLEKARIAGVGSLPLSG 787
Q L PQ + PPQP L P P Q P + A A GS L G
Sbjct: 981 PPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLG 1026
Score = 91.3 bits (225), Expect = 1e-17
Identities = 105/404 (25%), Positives = 142/404 (35%), Gaps = 49/404 (12%)
Query: 401 LPPP----PLTPPAPSPPPPLPPPSTSPPP---PLCPPPPPPVSPPPLPSPPPPPAQEEQ 453
LPPP P P P+PP PPP P P L P P P+ P P P PP A Q
Sbjct: 710 LPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVP-PHLPPYLAPASQ 768
Query: 454 EESPPPVVPATCSR------KRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPP 507
+P + P + + P + P AG +G P P TAT P
Sbjct: 769 VGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPV 828
Query: 508 EDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPK-------VEVS 560
+P L ++ + P A + +K P PP P V +
Sbjct: 829 PPPQYFSP--AVILPSLAAPLPPASPALPLQAVKLPH------PPGAPLAMPCRTIVPNA 880
Query: 561 PVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPP 620
P P + +PP + + + P P P P+ + + R PP
Sbjct: 881 PATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPP 940
Query: 621 PPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPE 680
P PP P P P P + P + PQ T + + VL P P+ P+P
Sbjct: 941 QPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPT------RPPQPVLPPQPM---LPPQPV 991
Query: 681 PPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQP 740
PP P PEP LP A TP + H AP + + P
Sbjct: 992 LPPQPALPVRPEPL------QPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP 1045
Query: 741 LQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGVGSLP 784
A+ + LP+ L P P+L P Q P A V S+P
Sbjct: 1046 PAAVLSPPLPEVLLPAAPELLP-----QFPSSLATVSASVQSVP 1084
Score = 81.3 bits (199), Expect = 1e-14
Identities = 104/396 (26%), Positives = 141/396 (35%), Gaps = 47/396 (11%)
Query: 385 AVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSP 444
A A ++ A+ + ++P PL P A PP P P P PL P + P LP+
Sbjct: 764 APASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTA 823
Query: 445 PPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTP-STAT 503
PP Q SP ++P+ + PL P+ A A P P P T
Sbjct: 824 TVPPVPPPQYFSPAVILPSLAA------PLPPASPALPLQAVKLPHPPGAPLAMPCRTIV 877
Query: 504 GGPPEDSP--TVAPKSTTFLKNIRQFI-----MPVVSARSSRVIKTPRRFMDEDPPKPPK 556
P P VAP L +I + PV A ++ T + PP P
Sbjct: 878 PNAPATIPLLAVAPPGVAAL-SIHSAVAQLPGQPVYPAAFPQMAPT------DVPPSPHH 930
Query: 557 VEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTR 616
+ PP PP P P P P P PT P PV P+ R +P +
Sbjct: 931 TVQNMRATPPQPALPPQPTLP-PQPVLPPQPTLPPQPVLPPQPTRP--PQPVLPPQPM-- 985
Query: 617 ELPPPPPAPPPPPAPSPP----------PAPATSSRRPLLLRAPQFTPSEAHLKIYESVL 666
LPP P PP P P P APA + +LL P P + +
Sbjct: 986 -LPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHP--APYAVDVAAQVPTV 1042
Query: 667 TPPPLGAPEAPEPE---PPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHG 723
PP P PE P + P P A + S+P + P + G
Sbjct: 1043 PVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLP--G 1100
Query: 724 APALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQ 759
P +++ T ++P+Q Q Q PP PQ
Sbjct: 1101 GPGIASPCPTVQLTVEPVQEEQAS---QDKPPGLPQ 1133
Score = 72.4 bits (176), Expect = 6e-12
Identities = 105/431 (24%), Positives = 143/431 (33%), Gaps = 93/431 (21%)
Query: 423 SPPPPLCPPPPPPV-----SPPPLPSPPPPPAQEEQEESPPPVVP---------ATCSRK 468
SP PP P V + P PP P E + PP +P +T
Sbjct: 560 SPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLPPTLPTSATSLASDSTFDSG 619
Query: 469 RGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQ-F 527
+G + SQ +++ + P+P+ PP V P+S L +Q
Sbjct: 620 QGSTVYSDSQSSQQSVMLG---SLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPT 676
Query: 528 IMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAP 587
P + S P P P + +PVL PP T P P +PAP P + P
Sbjct: 677 AAPGLPVGSVPAPACPPSLQQHFP--DPAMSFAPVLPPPSTPMPTGPGQPAP---PGQQP 731
Query: 588 TPPSTPVPLPEKRRSILREPTFRWTSLTRELPP--------------------------- 620
P + P PLP+ + +P + LPP
Sbjct: 732 PPLAQPTPLPQ---VLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPL 788
Query: 621 ---PPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFT-PSEAHLKIYESVLTPPPLGAPEA 676
PP PP P P P P L P T P + + + P L AP
Sbjct: 789 AQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLP 848
Query: 677 PE-----------PEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAP 725
P P PP A P R + ++P A V P A +S H A
Sbjct: 849 PASPALPLQAVKLPHPPGA---PLAMPCRTIVPNAPATIPLLA--VAPPGVAALSIHSAV 903
Query: 726 ALSNG----------------PQTQAQLLQPLQAL--QTQLLPQALPPPQPQLQPPPS-- 765
A G P + +Q ++A Q L PQ PPQP L P P+
Sbjct: 904 AQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLP 963
Query: 766 PQQMPPLEKAR 776
PQ + P + R
Sbjct: 964 PQPVLPPQPTR 974
Score = 70.1 bits (170), Expect = 3e-11
Identities = 172/698 (24%), Positives = 237/698 (33%), Gaps = 165/698 (23%)
Query: 1771 RRRCWYRCRILEYRPWGPREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPG 1830
R R W + E + G ++ + Q H+ A PP E+P D +L P
Sbjct: 543 RERIWPALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLPPT 602
Query: 1831 APERHSPIQNLDPPLRPDSGS---------------------APPPAPRSFSGARIKVPN 1869
P + + + D GS AP PA S + P
Sbjct: 603 LPTSATSLAS-DSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPV 661
Query: 1870 YSPSRRPLG---------GVSFGPLPSPGSPSSLTHHIPTVG---DPDFPAP----PRRS 1913
S LG G+ G +P+P P SL H P P P P P
Sbjct: 662 LPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGP 721
Query: 1914 RRPSPLAPRPPPSRWASP-PLKTSPQLRV---PPPTSVVTALTPTSGELAP----PGPAP 1965
+P+P +PPP +P P +PQ V P P + L P S AP P P
Sbjct: 722 GQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMP 781
Query: 1966 SPP--PPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDS 2023
P P + P + VV ++ A + G P ++ A
Sbjct: 782 QAPLQPLAQVPPQMPPIPVVPPITP-----LAGIDGLPPALPDLPTATV----------- 825
Query: 2024 SEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGT 2083
P +Y V + S P A+P P +AV+ P G
Sbjct: 826 ---PPVPPPQYFSPAVILPSLAAPLPPASPALP---------------LQAVKLPHPPGA 867
Query: 2084 P---------PSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPR-- 2132
P P+ P + +L A PP I V + G P A P+
Sbjct: 868 PLAMPCRTIVPNAPATI--PLLAVA-----PPGVAALSIHSAVAQLPGQPVYPAAFPQMA 920
Query: 2133 EESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPE-PPKPATSKI 2191
+PP+P Q + A+P P LP P +L P P PP+P
Sbjct: 921 PTDVPPSP-----HHTVQNMRATPPQPA-----LPPQP-----TLPPQPVLPPQPT---- 961
Query: 2192 ILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRP 2251
+PP QP LPP PT P LPP P+L PV+ +P
Sbjct: 962 -------------------LPP---QPVLPP--QPTRPPQPVLPPQPMLPPQPVL-PPQP 996
Query: 2252 APPPPPPPLT--LVLSSGPASPPRQAIRVKRVSTF----SGRSPPAPPPYKA---PRLDE 2302
A P P PL L + PA+ P I + + + + + P P P A P L E
Sbjct: 997 ALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPE 1056
Query: 2303 D--GEASEDTPQVP---GLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSP 2357
A E PQ P S V +T T+ + PG P G SP P + +
Sbjct: 1057 VLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLPGGP-GIASPCPTVQLT- 1114
Query: 2358 LLPLPEDGPPQVPDGPPDLLLESQWHHYSGEASSSEEE 2395
+ P+ E+ Q D PP L Y G +S +E
Sbjct: 1115 VEPVQEEQASQ--DKPPG--LPQSCESYGGSDVTSGKE 1148
Score = 62.0 bits (149), Expect = 8e-09
Identities = 90/369 (24%), Positives = 128/369 (34%), Gaps = 73/369 (19%)
Query: 430 PPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGP 489
P P P S PPLP PP E + P S+++ P SQ+ +A + P
Sbjct: 1322 PAPEAPESSPPLPLSSLPP---EASQDSAPYKDQLSSKEQ--PSFLASQQLLSQAGPSNP 1376
Query: 490 EGTSP----PTPTPSTAT---GGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKT 542
G P P+ P TA G P S P S T A + T
Sbjct: 1377 PGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGT--------------ASQAGGPGT 1422
Query: 543 PRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRS 602
P+ E P E T P+ +P V P P P +
Sbjct: 1423 PQGLTSELETSQPLAE---------THEAPLAVQPLVVGLAPCTPAPEAAST-------- 1465
Query: 603 ILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLR-APQFTPSEAHLKI 661
R S RE P P P+P P+P + + +P L + AP + + +
Sbjct: 1466 -------RDASAPRE---------PLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSL 1509
Query: 662 YESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSP 721
S L PPLG P P P+PP A +S E P PR V +T +
Sbjct: 1510 ATSQLPSPPLG-PTVP-PQPPSALESDGEGPP-----------PRVGFVDSTIKSLDEKL 1556
Query: 722 HGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGVG 781
+ P + A P++ + L QP+ + +PP+ K ++G
Sbjct: 1557 RTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRV 1616
Query: 782 SLPLSGVEE 790
LP VE+
Sbjct: 1617 QLPQPLVEK 1625
Score = 61.2 bits (147), Expect = 1e-08
Identities = 129/499 (25%), Positives = 183/499 (36%), Gaps = 77/499 (15%)
Query: 481 EREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVI 540
+ +A R GTSPP ST G E+S + + +N V+
Sbjct: 1264 DTDADRGSDPGTSPPHL--STCGLGTGEESRQSQANAPVYQQN---------------VL 1306
Query: 541 KTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKR 600
T +R+ + PV P +P P+ P+P P P ++
Sbjct: 1307 HTGKRWFI----------ICPVAEHP---APEAPESSPPLPLSSLPPEASQDSAPYKDQL 1353
Query: 601 RSILREPTFRWTSLTRELPP--PPPAPPPPPAPSPPP---------APATSSR-RPLLLR 648
S + L + P PP APP P APS PP APATS+ P
Sbjct: 1354 SSKEQPSFLASQQLLSQAGPSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGT 1413
Query: 649 APQFTPSEAHLKIYESVLTPPPLGAP-EAP-EPEPPPADDSPAEPEPRAVGRTNHLSLPR 706
A Q + + T PL EAP +P +P P P A T S PR
Sbjct: 1414 ASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAAS-TRDASAPR 1472
Query: 707 FAPVVTTPVKAEVSPH-GAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPS 765
P+ P E SPH G P + G Q L P L LP P L P
Sbjct: 1473 -EPL--PPPAPEPSPHSGTPQPALG---QPAPLLPAAVGAVSLATSQLP--SPPLGPTVP 1524
Query: 766 PQQMPPLEKARIAGVGSLPLSG-VEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPGG 824
PQ LE G G P G V+ + SL ++ + L++ + +A P+ G
Sbjct: 1525 PQPPSALESD---GEGPPPRVGFVDSTIKSLDEKLRTLLYQ-EHVPTSSASAGTPVEVGD 1580
Query: 825 QMEEVAGAVKQISDRGPVRSEDESV-----EAKRERPSGPESPVQGPRIKHVCRHAAVAL 879
+ + ++ R V D ++ EA R P+ V+ + R A +
Sbjct: 1581 R-DFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQPLVEKSELAPT-RGAVMEQ 1638
Query: 880 GQARAMVPEDVPRLSALPLRDRQDLATEDTSSASETESVPSRSRRGKVEA----AGPGGE 935
G + +M E PR RD + +A++ S + VP+ R +VE G GE
Sbjct: 1639 GTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAGE 1698
Query: 936 S--EPTGS-----GGTLAH 947
S EP S GG +H
Sbjct: 1699 SSAEPPPSDMGTVGGQASH 1717
Score = 52.0 bits (123), Expect = 8e-06
Identities = 110/448 (24%), Positives = 144/448 (32%), Gaps = 105/448 (23%)
Query: 1787 GPREEPAHLEAAEENQTIVHSP------APSSEPPGGE----DPPLDTDVLVPGAPERHS 1836
G + A Q ++H+ P +E P E PPL L P A + +
Sbjct: 1288 GEESRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPESSPPLPLSSLPPEASQDSA 1347
Query: 1837 PI---------------QNLDPPLRPDSGSAPPPAPRSFSGARIKV-------PNYSPSR 1874
P Q L P + PPAP + S + P S
Sbjct: 1348 PYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMP 1407
Query: 1875 RPLGGVSFGPLPSPGSPSSLTHHIPT------------------VG-DPDFPAPPRRSRR 1915
P G + PG+P LT + T VG P PAP S R
Sbjct: 1408 EPASGTA-SQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTR 1466
Query: 1916 PS--PLAPRPPPSRWASPPLKT-SPQLRVPPPT--SVVTALTPTSGELAPP--GPAPSPP 1968
+ P P PPP+ SP T P L P P + V A++ + +L P GP P
Sbjct: 1467 DASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQ 1526
Query: 1969 PPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGP-------- 2020
PP L D E G + + L T +QE + + A S G P
Sbjct: 1527 PPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSA---SAGTPVEVGDRDF 1583
Query: 2021 ------GDSSEEE------------SSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLD 2062
GD E S + P +V LAP T GA
Sbjct: 1584 TLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQPLVEKSELAP--TRGAV------ 1635
Query: 2063 GVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLG 2122
++ GT S A PR S G R G A+ P +P ++ FV
Sbjct: 1636 -MEQGTSSSMTAESSPR------SMLGYDRDGRQVASDSHVVP--SVPQDVPAFVRPARV 1686
Query: 2123 GPGDGGAGPREESLPPAPPLANGSQPSQ 2150
P D G ES PP G+ Q
Sbjct: 1687 EPTDRDGGEAGESSAEPPPSDMGTVGGQ 1714
Score = 48.9 bits (115), Expect = 7e-05
Identities = 60/239 (25%), Positives = 86/239 (35%), Gaps = 32/239 (13%)
Query: 379 EEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSP 438
E ++ A ++ + + E+ L+ PS PP +PP PL P PP +
Sbjct: 1341 EASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPP------GAPPAPLAPSSPPVTAL 1394
Query: 439 P-----PLPSPPPPPAQEEQEESPPPVVP-ATCSRKRGRPPLTPSQRAEREAARAGPEGT 492
P P S P PA ++ P P S PL + A A + G
Sbjct: 1395 PQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPL-AVQPLVVGL 1453
Query: 493 SPPTPTPSTAT----GGPPEDSPTVAPKSTTFLKNIRQFI---MPVVSARSSRVIKTPRR 545
+P TP P A+ P E P AP+ + + + P++ A V +
Sbjct: 1454 APCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQ 1513
Query: 546 FMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSIL 604
P PP L P + PP E PPR ST L EK R++L
Sbjct: 1514 L-----PSPP-------LGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLL 1560
Score = 48.1 bits (113), Expect = 1e-04
Identities = 73/278 (26%), Positives = 97/278 (34%), Gaps = 55/278 (19%)
Query: 551 PPKPPKVEVSPVLRPPITTSPPVPQE-------PAPVPSPPRAPTPPST----PVPLPEK 599
P PK E V P PPVP + A P PP P + P LP
Sbjct: 548 PALQPK-EQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLPPTLPTS 606
Query: 600 RRSILREPTF---RWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSE 656
S+ + TF + +++ + + P+PA P + P S
Sbjct: 607 ATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSL 666
Query: 657 AHLKIYESVLTPPPLGAPEAPEPE--------------------PPPADDSPAEP-EPRA 695
L Y+ P L P P PPP+ P P +P
Sbjct: 667 PSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPAP 726
Query: 696 VGR-----TNHLSLPR-FAP---VVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQT 746
G+ LP+ AP V PV + P+ APA G Q L+PLQ Q
Sbjct: 727 PGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQ---LKPLQMPQA 783
Query: 747 QLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGVGSLP 784
L P A PP Q PP P +PP+ +AG+ LP
Sbjct: 784 PLQPLAQVPP----QMPPIP-VVPPI--TPLAGIDGLP 814
Score = 48.1 bits (113), Expect = 1e-04
Identities = 87/362 (24%), Positives = 114/362 (31%), Gaps = 85/362 (23%)
Query: 388 EEMMPAAEKEEAKLPPPPLT------PPAP---------SPPPPLPPPSTSPPPPLCPPP 432
E P AE EA L PL PAP +P PLPPP+ P P P
Sbjct: 1431 ETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQ 1490
Query: 433 PPPVSPPP---------------LPSPP--------PPPAQEEQEESPPPVV-------- 461
P P P LPSPP PP A E E PPP V
Sbjct: 1491 PALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIK 1550
Query: 462 --------------PATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPT----------P 497
T S G TP + +R+ G P + P
Sbjct: 1551 SLDEKLRTLLYQEHVPTSSASAG----TPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPP 1606
Query: 498 TPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKV 557
P A G + + KS L R +M ++ S +PR + D
Sbjct: 1607 VPKEAVSGRVQLPQPLVEKSE--LAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVA 1664
Query: 558 EVSPVLRPPITTSPPVPQEPAPVPSPPR--APTPPSTPVPLPEKRRSILREPTFRWTSLT 615
S V+ P + P PA V R S+ P P ++ + + T
Sbjct: 1665 SDSHVV-PSVPQDVPAFVRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGA 1723
Query: 616 RELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPE 675
R L P P SP T R ++ ++T + H Y + PP + E
Sbjct: 1724 RALGSPRKRPEQQDVSSP---AKTVGRFSVVSTQDEWTLASPHSLRYSA---PPDVYLDE 1777
Query: 676 AP 677
AP
Sbjct: 1778 AP 1779
Score = 45.4 bits (106), Expect = 7e-04
Identities = 57/230 (24%), Positives = 82/230 (35%), Gaps = 55/230 (23%)
Query: 2084 PPSGPGVVRAGVLGAAGDRARPPEDL------PSEIVDFVLKNLGGPGDGGAGPREESLP 2137
P S P + + + A + P +D PS + L + GP + P P
Sbjct: 1327 PESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAPLAP 1386
Query: 2138 PAPPLA----NGSQPSQGLTASPADPTRTFAWLPGAP---------------------GV 2172
+PP+ +G+ P+ PA T + A PG P V
Sbjct: 1387 SSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPLAV 1446
Query: 2173 RVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSW 2232
+ L +G AP P P + + EP+PPP +P P + +P
Sbjct: 1447 QPLVVGLAPCTPAPEAASTR----------DASAPREPLPPPAPEPS-PHSGTPQPALG- 1494
Query: 2233 TLPPGPLL----GVLPVVGVVRPAPP-----PPPPPLTLVLSSGPASPPR 2273
P PLL G + + P+PP PP PP L S G PPR
Sbjct: 1495 --QPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALE-SDGEGPPPR 1541
Score = 40.4 bits (93), Expect = 0.024
Identities = 44/183 (24%), Positives = 63/183 (34%), Gaps = 27/183 (14%)
Query: 2128 GAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPA 2187
GAGP + P A G Q + +D PG+ P P+PP+P
Sbjct: 20 GAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEP-------PGLEAAE-APGPQPPQPL 71
Query: 2188 TSKIILVNKLGQVFVKMAGEGEPVPPP----VKQPPLPPTISPTAPTS-WTLPPGPLLGV 2242
+++L+ K ++ + A G P P V QP P + P T PGP
Sbjct: 72 QRRVLLLCKTRRLIAERA-RGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQEPGP---- 126
Query: 2243 LPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDE 2302
P+ V AP P GP +R + + P P +E
Sbjct: 127 DPIAAAVETAPAP---------DGGPREEAAATVRKEDEGAAEAKPEPGRTRRDEPEEEE 177
Query: 2303 DGE 2305
D E
Sbjct: 178 DDE 180
Score = 35.0 bits (79), Expect = 1.0
Identities = 28/86 (32%), Positives = 36/86 (41%), Gaps = 4/86 (4%)
Query: 388 EEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPP--PPLCPPPPPPVSPPPLPSPP 445
E ++PAA + + P T A P + PP PPL P P SP P
Sbjct: 1056 EVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPPL-PGGPGIASPCPTVQLT 1114
Query: 446 PPPAQEEQ-EESPPPVVPATCSRKRG 470
P QEEQ + PP +P +C G
Sbjct: 1115 VEPVQEEQASQDKPPGLPQSCESYGG 1140
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 97.4 bits (241), Expect = 2e-19
Identities = 127/488 (26%), Positives = 168/488 (34%), Gaps = 82/488 (16%)
Query: 392 PAAEKEEAK----LPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPP 447
PAA EA + P P PPA S P PL P P P +PP +P P
Sbjct: 608 PAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPS 667
Query: 448 PAQEEQEE-----SPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSP-------P 495
P E PP P + P +R+++ + GP + P P
Sbjct: 668 PGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAP 727
Query: 496 TPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPP 555
P A P + P++ + + P ++ +K P P
Sbjct: 728 PPAQDPAPATPVAKGAGLGPQA----PDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQA 783
Query: 556 KVEVSPVLRPPITTSPP--VPQEPAPVPSPPRAP-----TPPSTPVPLP---EKRRSILR 605
+ SP L P T PP P P V PP P PP P LP + +
Sbjct: 784 PLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGV 843
Query: 606 EPTFRWTSLTRELPPPPPAPPP--------PPAPSPPP---APATSSRRPLLLRAPQFTP 654
P + T PP PP P PPAP PP + A +S R P TP
Sbjct: 844 PPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTP 903
Query: 655 SEAHLKI------YESVLTPPPLG-APEAPEPEPPP-------ADDSPAEPEPRAVGRTN 700
S+ L+ ++S PP L PE P PPP PA P+P+A+
Sbjct: 904 SDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKAL---- 959
Query: 701 HLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQL 760
L RF V + + + GAPA PQT L PL + +L P
Sbjct: 960 ---LERFHQ-VPSGIILQNKAGGAPA---APQTSTS-LGPLTSPAASVLVSGQAPSGTPT 1011
Query: 761 QPPPSPQQMPPLEKARIAGVGSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPL 820
P +P P +A G PL E K F+ + K A+S P
Sbjct: 1012 APSHAPAPAP------MAATGLPPLLPAENKAFA---------SNLPTLNVAKAASSGPG 1056
Query: 821 SPGGQMEE 828
P G E
Sbjct: 1057 KPSGLQYE 1064
Score = 70.9 bits (172), Expect = 2e-11
Identities = 117/467 (25%), Positives = 163/467 (34%), Gaps = 92/467 (19%)
Query: 1885 LPSPGSPSSLTHHI-PTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPP 1943
L P +P++ T P + P P P PL + P ++ PP +PQ PP
Sbjct: 602 LVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQ--QPPQAPTPQAAAPP 659
Query: 1944 PTSVVTALTPTSGELAPP-----GPAPSPPPPEDLGPDFEDMEVVSGLSAADLDF----- 1993
T P+ G + P G PS P L D M + S L
Sbjct: 660 QA---TTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHL 716
Query: 1994 ---AASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAP--GLA 2048
A+ ++ P ++ A + G + + ++SP P +AP G
Sbjct: 717 SVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPA----PQIPAAAPLKGPG 772
Query: 2049 PSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPED 2108
PS++P P L G + R PPS P V PP+
Sbjct: 773 PSSSPSLPHQAPL-----GDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQA 827
Query: 2109 LPSEIVDFVLKN-LGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLP 2167
P+ FV++N LG P PP PPL SQP +G
Sbjct: 828 PPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEG---------------- 871
Query: 2168 GAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVK-QPPLPPTISP 2226
L PAP P +TS + + P P P Q PP+ P
Sbjct: 872 --------PLPPAPHLPPSSTSSAVASSS-------ETSSRLPAPTPSDFQLQFPPSQGP 916
Query: 2227 -TAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLT--LVLSSGPASPPRQAI--RVKRV 2281
+PT P P L ++P PA PPPPPP T +V + PA P +A+ R +V
Sbjct: 917 HKSPT-----PPPTLHLVP-----EPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQV 966
Query: 2282 ------STFSGRSPPAPP------PYKAPRLD--EDGEASEDTPQVP 2314
+G +P AP P +P G+A TP P
Sbjct: 967 PSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAP 1013
Score = 60.8 bits (146), Expect = 2e-08
Identities = 117/468 (25%), Positives = 155/468 (33%), Gaps = 140/468 (29%)
Query: 392 PAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPP--LCPPPPPPVSPPP--LPS---- 443
PA + K PP T A PP PP + S P L V P LP
Sbjct: 417 PALQANVFKQPPATTTGAA----PPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQF 472
Query: 444 --PPPPPAQEEQEESPPP----------VVPATCSRKRGRPPLTPSQRA----------- 480
P P Q Q+ S P P T + P LT A
Sbjct: 473 LLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAP 532
Query: 481 -----EREAARAGPEGTSPPT----PTPSTATGGPPEDSPTVA-PKSTTFLKNIRQFIMP 530
A P P P A P + P A P +TT L+ +
Sbjct: 533 HSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGV------ 586
Query: 531 VVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPP 590
+ + ++ TP + P E +PVL T P PQ P V
Sbjct: 587 TLPPSAVAMLNTPDGLVQPATPAAATGEAAPVL-----TVQPAPQAPPAV---------- 631
Query: 591 STPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAP--ATSSRRPLLLR 648
STP+PL ++ + P P P A PP A +P P+P A+S + +L +
Sbjct: 632 STPLPLGLQQPQAQQPPQ----------APTPQAAAPPQATTPQPSPGLASSPEKIVLGQ 681
Query: 649 APQFTPSE------------------------AHLKIYESVL--TPPPL----------- 671
P TP+ HL + SV+ PPP
Sbjct: 682 PPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAK 741
Query: 672 GA---PEAPEPE--PPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPA 726
GA P+AP+ + P PA PA + G ++ SLP AP+ +P SPH
Sbjct: 742 GAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLP--SPHPTRP 799
Query: 727 LSNGPQTQAQLLQPLQALQTQLLPQAL--PPPQPQLQPPPSPQQMPPL 772
S P PQ++ PP +P L P P PQ P L
Sbjct: 800 PSRPPSR----------------PQSVSRPPSEPPLHPCPPPQAPPTL 831
Score = 60.1 bits (144), Expect = 3e-08
Identities = 171/682 (25%), Positives = 231/682 (33%), Gaps = 156/682 (22%)
Query: 1809 APSSEPPG---GEDPPLDTDVLVPGAPERHSPIQNLDPPLRPD-SGSAPP------PAPR 1858
AP+ P G P L + LVP AP + + P++P +G PP P P
Sbjct: 315 APTGTPSGQPLAVAPGLGSSPLVP-AP--NVILHRTPTPIQPKPAGVLPPKLYQLTPKPF 371
Query: 1859 SFSGARIKVPNYSPSRRPLGGVSFGPLPS-PGSPSSLTHHIPTVGDPD-----FPAPPRR 1912
+ +GA + + G LP P +P +LT + FPAP +
Sbjct: 372 APAGATLTIQGEP-----------GALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQ 420
Query: 1913 S---RRP----SPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTA--LTPTSGELAPPGP 1963
+ ++P + AP PP + P S L + V+ A + P + PG
Sbjct: 421 ANVFKQPPATTTGAAPPQPPGALSKP---MSVHLLNQGSSIVIPAQHMLPGQNQFLLPG- 476
Query: 1964 APSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMG-----SSHG 2018
AP+ P+ L V + AA L P AG + + H
Sbjct: 477 APAVQLPQQLSA--LPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHS 534
Query: 2019 GPGDSSEEESSP--TSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQ 2076
G + ++P + F + V A G P+ + AP V G AV
Sbjct: 535 GAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVA 594
Query: 2077 QPRGQGTPPSGPGVVRAGVLGAAGDRARP-----PEDLPSEIVDFVLKNLGGPGDGGAGP 2131
TP G+V+ AA A P P V L LG P
Sbjct: 595 M---LNTPD---GLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLP-LGLQQPQAQQP 647
Query: 2132 REESLPPA--PPLANGSQPSQGLTASP----------ADPTRTFA------WLP------ 2167
+ P A PP A QPS GL +SP A PT +LP
Sbjct: 648 PQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQ 707
Query: 2168 ---------GAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQ- 2217
P ++S P + P PAT V K G A + + P P Q
Sbjct: 708 PLSAEGPHLSVPASVIVSAPPPAQDPAPATP----VAK-GAGLGPQAPDSQASPAPAPQI 762
Query: 2218 PPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIR 2277
P P P +S +LP LG P + P+P P PP S P S P+
Sbjct: 763 PAAAPLKGPGPSSSPSLPHQAPLGDSPHL----PSPHPTRPP------SRPPSRPQSV-- 810
Query: 2278 VKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDL 2337
R P PP + P PQ P PT+ G+ +
Sbjct: 811 --------SRPPSEPPLHPCP-----------PPQAP--------------PTLPGIFVI 837
Query: 2338 DRP-GEPAGEESPGPLQERSPLLPL-PEDGPPQVPDGPPDLLLESQWHHYSGEASSSEEE 2395
G P +P P P PL P+ PP+ P P L S S ASSSE
Sbjct: 838 QNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTS--SAVASSSETS 895
Query: 2396 P----PSPDDKENQAPKRTGPH 2413
P+P D + Q P GPH
Sbjct: 896 SRLPAPTPSDFQLQFPPSQGPH 917
Score = 58.5 bits (140), Expect = 9e-08
Identities = 77/266 (28%), Positives = 97/266 (36%), Gaps = 40/266 (15%)
Query: 1808 PAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKV 1867
P PSS P PL P P H PP RP S S PP P
Sbjct: 771 PGPSSSPSLPHQAPLGDS---PHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLH------- 820
Query: 1868 PNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRR-----PSPLAPR 1922
P P P F G P ++ PT P P PP R + P P AP
Sbjct: 821 PCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGP--PQPPLRPQSQPPEGPLPPAPH 878
Query: 1923 PPPSRWASPPL---KTSPQLRVPPPTSVVTALTPTSGELAPPGPAP---------SPPPP 1970
PPS +S +TS +L P P+ P+ G P P P +PPPP
Sbjct: 879 LPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPP 938
Query: 1971 EDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSP 2030
P V + A L +LL E F + V +G + + G G + ++S
Sbjct: 939 ----PPRTFQMVTTPFPA--LPQPKALL--ERFHQ--VPSGIILQNKAG-GAPAAPQTST 987
Query: 2031 TSRYIHFPVTVVSAPGLAPSATPGAP 2056
+ + P V G APS TP AP
Sbjct: 988 SLGPLTSPAASVLVSGQAPSGTPTAP 1013
Score = 57.0 bits (136), Expect = 2e-07
Identities = 62/195 (31%), Positives = 73/195 (37%), Gaps = 30/195 (15%)
Query: 1788 PREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRP 1847
P+E +AE V + S PP +DP T V GA P P
Sbjct: 701 PQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPV-AKGAGLG---------PQAP 750
Query: 1848 DSGSAPPPAPRSFSGARIKVPNYS-----PSRRPLGGVSFGPLPSPGSPSSLTHHIPTVG 1902
DS ++P PAP+ + A +K P S P + PLG P P P P S
Sbjct: 751 DSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPS--------R 802
Query: 1903 DPDFPAPPRRSRRPSPLAPRPPPSRWASPP--LKTSPQLRVPPPTS--VVTALTPTSGEL 1958
P P R PL P PPP + P QL VPPP S TA P L
Sbjct: 803 PPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPL 862
Query: 1959 AP---PGPAPSPPPP 1970
P P P PP P
Sbjct: 863 RPQSQPPEGPLPPAP 877
Score = 53.5 bits (127), Expect = 3e-06
Identities = 65/261 (24%), Positives = 85/261 (32%), Gaps = 31/261 (11%)
Query: 403 PPPLTPPAPSPP-PPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVV 461
PPP + PAP+ P PP PP PP P PP P PP S + E P P
Sbjct: 844 PPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAP-- 901
Query: 462 PATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFL 521
TPS + GP + P PT PE + P TF
Sbjct: 902 -------------TPSDFQLQFPPSQGPHKSPTPPPTLHLV----PEPAAPPPPPPRTFQ 944
Query: 522 KNIRQF-IMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPV 580
F +P A R + P + ++ K +P T+ P+ A V
Sbjct: 945 MVTTPFPALPQPKALLERFHQVPSGIILQN-----KAGGAPAAPQTSTSLGPLTSPAASV 999
Query: 581 ----PSPPRAPTPPS-TPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPP 635
+P PT PS P P P + + LP A P P
Sbjct: 1000 LVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPS 1059
Query: 636 APATSSRRPLLLRAPQFTPSE 656
S+ L + P PS+
Sbjct: 1060 GLQYESKLSGLKKPPTLQPSK 1080
Score = 53.5 bits (127), Expect = 3e-06
Identities = 82/329 (24%), Positives = 107/329 (32%), Gaps = 48/329 (14%)
Query: 347 GQGGSPC--WKKQEQKLDDEEEEKKEEEEKDKEGEE----------KEERAVAEEMMPAA 394
G GGSP W + L D + + K A + +
Sbjct: 1252 GAGGSPSVTWARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLK 1311
Query: 395 EKEEAKLPP----PPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQ 450
K+EA L L P PPPP PPP PPPPP PPP A
Sbjct: 1312 IKQEAGLSKVVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAP 1371
Query: 451 EEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDS 510
E + P P R PL + R E PEGT A GG P
Sbjct: 1372 ERKPLGTAPHCP--------RLPLRKTYR-ENVGGPGAPEGT-----PAGRARGGSPAPL 1417
Query: 511 PTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTS 570
P ++T+ L IR+ + V R++K P PP+P P
Sbjct: 1418 PAKVDEATSGL--IRE-LAAVEDELYQRMLKGP-------PPEPAASAAQGTGDPDWEAP 1467
Query: 571 PPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPA 630
P + SP S+ P + L+ +L + AP PA
Sbjct: 1468 GLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQ-------APGRTPA 1520
Query: 631 PS-PPPAPATSSRRPLLLRAPQFTPSEAH 658
PS P A A + P L P+ P +H
Sbjct: 1521 PSYPHAASAGTPASPPPLHRPEAYPPSSH 1549
Score = 52.4 bits (124), Expect = 6e-06
Identities = 45/168 (26%), Positives = 55/168 (32%), Gaps = 50/168 (29%)
Query: 390 MMPAAEKEEAKLPPPPLTPPAPSP-------------PPPLP-------PPSTSPPPPLC 429
+ P ++ E LPP P PP+ + P P P PPS P
Sbjct: 862 LRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPT 921
Query: 430 PPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVP---------------ATCSRKRGRPPL 474
PPP + P P PPPPP + +P P +P K G P
Sbjct: 922 PPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPA 981
Query: 475 TP----------SQRAEREAARAGPEGT-----SPPTPTPSTATGGPP 507
P S A + P GT P P P ATG PP
Sbjct: 982 APQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPP 1029
Score = 45.8 bits (107), Expect = 6e-04
Identities = 60/212 (28%), Positives = 78/212 (36%), Gaps = 38/212 (17%)
Query: 1785 PWGPREEPAHLEAAEENQTIVHSPAPSSEP----PGGEDPPLDTDVLVPGAPERHSPIQN 1840
P P + P L Q + P P+S P PG PPL P+ P
Sbjct: 821 PCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPL--------RPQSQPPEGP 872
Query: 1841 LDP-PLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIP 1899
L P P P S ++ A S + +R+ P S + S GP SP P +L H +P
Sbjct: 873 LPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPP-SQGPHKSPTPPPTL-HLVP 930
Query: 1900 TVGDPDFPAPPRRSRR---PSPLAPRPP---------PSRW----------ASPPLKTSP 1937
P P PPR + P P P+P PS A+P TS
Sbjct: 931 EPAAPP-PPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSL 989
Query: 1938 QLRVPPPTSVVTALTPTSGELAPPGPAPSPPP 1969
P SV+ + SG P AP+P P
Sbjct: 990 GPLTSPAASVLVSGQAPSGTPTAPSHAPAPAP 1021
Score = 44.7 bits (104), Expect = 0.001
Identities = 84/354 (23%), Positives = 120/354 (33%), Gaps = 52/354 (14%)
Query: 560 SPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELP 619
+P L+ + PP A P PP A + P + V L + SI+ + L
Sbjct: 416 APALQANVFKQPPATTTGAAPPQPPGALSKPMS-VHLLNQGSSIVIPAQHMLPGQNQFLL 474
Query: 620 PPPPAPPPPPAPSPPP-----------APATSSR---RPLL-------------LRAPQF 652
P PA P S P AP T + P+L + AP
Sbjct: 475 PGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHS 534
Query: 653 TPSEAHLKIYESVLTPPP--LGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPV 710
AH+ + P P + P PA P A ++LP A
Sbjct: 535 GAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVA 594
Query: 711 VTTPVKAEVSPHGAPALSNGPQTQAQLLQPL----QALQTQL-----LPQALPPPQ---P 758
+ V P PA + G +QP A+ T L PQA PPQ P
Sbjct: 595 MLNTPDGLVQP-ATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTP 653
Query: 759 QLQPPP---SPQQMPPLEKARIAGVGSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVA 815
Q PP +PQ P L + V P S ++L + +Q+F ++ QQ ++
Sbjct: 654 QAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPT---AILTQDSLQMFLPQERSQQPLS 710
Query: 816 ASMP-LSPGGQMEEVAGAVKQISDRGPVRSEDESVEAKRERPSGPESPVQGPRI 868
A P LS + + A D P + + P SP P+I
Sbjct: 711 AEGPHLSVPASV--IVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQI 762
Score = 43.9 bits (102), Expect = 0.002
Identities = 89/368 (24%), Positives = 129/368 (35%), Gaps = 78/368 (21%)
Query: 129 DEDVAPS---SLRSALRSQRGRAPRGRGRKHKTTP----LPPPRLADVAPTPPKTPARKR 181
DE V+ S L A S+ R P G G + P PPP L P K R
Sbjct: 1199 DEYVSSSRSLGLPIAASSEGHRLP-GHGPLSSSAPGASTQPPPHL------PTKLVIRHG 1251
Query: 182 GEEGTERMV--QALTELLRRAQAPQAPRSRACEPSTPRRSRGRPP-------GRPAGPCR 232
G G+ + +A + L + + A S + P SR RPP R +
Sbjct: 1252 GAGGSPSVTWARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLK 1311
Query: 233 RKQQAVVV------------------AEAAVTIPKPEPPPPVVP-------VKHQTGSWK 267
KQ+A + A V P P PPPP P V H +
Sbjct: 1312 IKQEAGLSKVVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAP 1371
Query: 268 CKEGPGPGPGTP----RRGGQSSRGGRGG-----RGRGRGGGLPFVIKFVSRAKKVKMGQ 318
++ G P P R+ + + GG G GR RGG + V A + +
Sbjct: 1372 ERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRE 1431
Query: 319 LSLGLESGQGQGQHEESWQDV-----PQRRVGSGQG-GSPCWKKQEQKLDDEEEEKKEEE 372
L+ +E +Q + P+ + QG G P W + L + K E
Sbjct: 1432 LA---------AVEDELYQRMLKGPPPEPAASAAQGTGDPDW--EAPGLPPAKRRKSESP 1480
Query: 373 EKDK---EGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLC 429
+ D+ + ++ + E + A + L P PAPS P + + PPPL
Sbjct: 1481 DVDQASFSSDSPQDDTLTEHLQSAID-SILNLQQAPGRTPAPSYPHAASAGTPASPPPLH 1539
Query: 430 PPPPPPVS 437
P P S
Sbjct: 1540 RPEAYPPS 1547
Score = 38.1 bits (87), Expect = 0.12
Identities = 43/157 (27%), Positives = 57/157 (36%), Gaps = 55/157 (35%)
Query: 619 PPPPPAP----PPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAP 674
PPPPPA PPP P PPP PPP G
Sbjct: 1333 PPPPPATLKVAEPPPRP-PPP--------------------------------PPPTGQM 1359
Query: 675 EAPEPEPPPADDSPAEPEPRAVGRTNHL-SLP---RFAPVVTTPVKAEVSPHG------- 723
PP PA PE + +G H LP + V P E +P G
Sbjct: 1360 NGTVDHPP-----PAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSP 1414
Query: 724 APALSNGPQTQAQLLQPLQALQTQLLPQAL--PPPQP 758
AP + + + L++ L A++ +L + L PPP+P
Sbjct: 1415 APLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEP 1451
Score = 37.0 bits (84), Expect = 0.27
Identities = 47/173 (27%), Positives = 64/173 (36%), Gaps = 24/173 (13%)
Query: 1832 PERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSP 1891
P + ++ +PP RP PPP +G P +P R+PLG P P
Sbjct: 1334 PPPPATLKVAEPPPRPPP---PPPPTGQMNGTVDHPPPAAPERKPLGTAPH----CPRLP 1386
Query: 1892 SSLTHHIPTVGDPDFP--APPRRSRRPSPLAPRPPPSRWASPPL----------KTSPQL 1939
T+ VG P P P R+R SP AP P A+ L L
Sbjct: 1387 LRKTYR-ENVGGPGAPEGTPAGRARGGSP-APLPAKVDEATSGLIRELAAVEDELYQRML 1444
Query: 1940 RVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLD 1992
+ PPP +A T P AP PP + + D++ S S + D
Sbjct: 1445 KGPPPEPAASAAQGTGD---PDWEAPGLPPAKRRKSESPDVDQASFSSDSPQD 1494
Score = 35.0 bits (79), Expect = 1.0
Identities = 60/233 (25%), Positives = 81/233 (34%), Gaps = 61/233 (26%)
Query: 2098 AAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPA 2157
A G +PP LP+++V +++ G G P + L++ S S ++ A
Sbjct: 1231 APGASTQPPPHLPTKLV---IRH----GGAGGSPSVTWARASSSLSSSSSSSSAASSLDA 1283
Query: 2158 DPTRTFAWLPGAPGVRVLSLGPAPEPPKP------ATSKIILVNKLGQVFVKMAGEGEPV 2211
D GP P +P A S+I L K+ Q
Sbjct: 1284 DED-----------------GPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTA 1326
Query: 2212 PPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAP-PPPPPPLTLVLSSGPAS 2270
PV QPP PP + V P P PPPPPP T ++
Sbjct: 1327 LDPVHQPPPPPA---------------------TLKVAEPPPRPPPPPPPTGQMNGTVDH 1365
Query: 2271 PPRQAIRVKRVSTFSGRSPPAP--PPYKAPRLDEDGE-ASEDTPQVPGLGSGG 2320
PP A K + G +P P P K R + G A E TP G GG
Sbjct: 1366 PPPAAPERKPL----GTAPHCPRLPLRKTYRENVGGPGAPEGTP--AGRARGG 1412
Score = 34.3 bits (77), Expect = 1.7
Identities = 43/167 (25%), Positives = 61/167 (36%), Gaps = 19/167 (11%)
Query: 2136 LPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVN 2195
LP PL++ S P P PT+ GA G ++ A ++S +
Sbjct: 1221 LPGHGPLSS-SAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAAS 1279
Query: 2196 KLGQVFVKMAGEGEPVP----PPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVG--VV 2249
L A E P+P PP+K T + L G+ VV +
Sbjct: 1280 SLD------ADEDGPMPSRNRPPIK------TYEARSRIGLKLKIKQEAGLSKVVHNTAL 1327
Query: 2250 RPAPPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYK 2296
P PPPPP TL ++ P PP +++ PPA P K
Sbjct: 1328 DPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERK 1374
Score = 32.7 bits (73), Expect = 5.0
Identities = 57/235 (24%), Positives = 84/235 (35%), Gaps = 25/235 (10%)
Query: 2078 PRGQGTPPSGPGVVRAGVLGAAGDR--ARPPEDLPSEIVDFVLKNLGGPG--DGGAGPRE 2133
P QG P PG A LG A + +P L + + K + G AGP E
Sbjct: 212 PGLQGLPNGSPGGATAATLGLAPIQVVGQPVMALNTPTSQLLAKQVPVSGYLASAAGPSE 271
Query: 2134 E---SLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEP--PKPAT 2188
+ P G + L+A+ A + GA + P+ +P P
Sbjct: 272 PVTLASAGVSPQGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGTPSGQPLAVAPGL 331
Query: 2189 SKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGV 2248
LV + + +P P V LPP + P + P G L + G
Sbjct: 332 GSSPLVPAPNVILHRTPTPIQPKPAGV----LPPKLYQLTPKPFA-PAGATLTIQGEPGA 386
Query: 2249 VRPAPPPPPPPLT----------LVLSSGPASPPRQAIRVKRVSTFSGRSPPAPP 2293
+ P P P LT +VLS PA + + + +T +G +PP PP
Sbjct: 387 L-PQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPP 440
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.136 0.428
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 162,692,025
Number of Sequences: 37866
Number of extensions: 12461044
Number of successful extensions: 301409
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1759
Number of HSP's successfully gapped in prelim test: 2654
Number of HSP's that attempted gapping in prelim test: 67301
Number of HSP's gapped (non-prelim): 104521
length of query: 2715
length of database: 18,247,518
effective HSP length: 120
effective length of query: 2595
effective length of database: 13,703,598
effective search space: 35560836810
effective search space used: 35560836810
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.