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Search of human proteins with 7662036
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7662036 sparc/osteonectin, cwcv and kazal-like domains
proteoglycan (testican) 2 isoform 2 [Homo sapiens]
(424 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7662036 sparc/osteonectin, cwcv and kazal-like domains proteo... 898 0.0
gi|93141001 testican 3 isoform 2 [Homo sapiens] 414 e-116
gi|93141003 testican 3 isoform 1 [Homo sapiens] 403 e-112
gi|4759164 sparc/osteonectin, cwcv and kazal-like domains proteo... 375 e-104
gi|197313714 sparc/osteonectin, cwcv and kazal-like domains prot... 133 3e-31
gi|190194423 SPARC-like 1 [Homo sapiens] 61 2e-09
gi|190341024 SPARC-like 1 [Homo sapiens] 61 2e-09
gi|115298674 nidogen 1 precursor [Homo sapiens] 60 5e-09
gi|68448544 CD74 antigen isoform a [Homo sapiens] 56 5e-08
gi|24308277 SPARC related modular calcium binding 2 [Homo sapiens] 56 5e-08
gi|4507171 secreted protein, acidic, cysteine-rich [Homo sapiens] 55 1e-07
gi|11321593 insulin-like growth factor binding protein 6 [Homo s... 55 2e-07
gi|78190498 secreted modular calcium-binding protein 1 isoform 1... 53 5e-07
gi|11545873 secreted modular calcium-binding protein 1 isoform 2... 53 5e-07
gi|62243068 insulin-like growth factor binding protein 3 isoform... 52 8e-07
gi|62243248 insulin-like growth factor binding protein 3 isoform... 52 8e-07
gi|55770862 thyroglobulin [Homo sapiens] 52 1e-06
gi|144953895 nidogen 2 precursor [Homo sapiens] 51 2e-06
gi|10834982 insulin-like growth factor binding protein 5 [Homo s... 49 7e-06
gi|54873613 agrin [Homo sapiens] 49 9e-06
gi|5901956 follistatin-like 1 precursor [Homo sapiens] 47 3e-05
gi|4504615 insulin-like growth factor binding protein 1 precurso... 43 5e-04
gi|5453652 follistatin isoform FST317 precursor [Homo sapiens] 43 6e-04
gi|7242222 follistatin isoform FST344 precursor [Homo sapiens] 43 6e-04
gi|55925576 insulin-like growth factor binding protein 2, 36kDa ... 42 8e-04
gi|166795236 tumor-associated calcium signal transducer 2 precur... 42 8e-04
gi|19923632 Kazal-type serine peptidase inhibitor domain 1 precu... 42 0.001
gi|29568105 transmembrane protein with EGF-like and two follista... 41 0.002
gi|218505670 epithelial cell adhesion molecule precursor [Homo s... 41 0.002
gi|62243290 insulin-like growth factor binding protein 4 precurs... 39 0.007
>gi|7662036 sparc/osteonectin, cwcv and kazal-like domains
proteoglycan (testican) 2 isoform 2 [Homo sapiens]
Length = 424
Score = 898 bits (2321), Expect = 0.0
Identities = 424/424 (100%), Positives = 424/424 (100%)
Query: 1 MRAPGCGRLVLPLLLLAAAALAEGDAKGLKEGETPGNFMEDEQWLSSISQYSGKIKHWNR 60
MRAPGCGRLVLPLLLLAAAALAEGDAKGLKEGETPGNFMEDEQWLSSISQYSGKIKHWNR
Sbjct: 1 MRAPGCGRLVLPLLLLAAAALAEGDAKGLKEGETPGNFMEDEQWLSSISQYSGKIKHWNR 60
Query: 61 FRDEVEDDYIKSWEDNQQGDEALDTTKDPCQKVKCSRHKVCIAQGYQRAMCISRKKLEHR 120
FRDEVEDDYIKSWEDNQQGDEALDTTKDPCQKVKCSRHKVCIAQGYQRAMCISRKKLEHR
Sbjct: 61 FRDEVEDDYIKSWEDNQQGDEALDTTKDPCQKVKCSRHKVCIAQGYQRAMCISRKKLEHR 120
Query: 121 IKQPTVKLHGNKDSICKPCHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQLAVRCEGPC 180
IKQPTVKLHGNKDSICKPCHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQLAVRCEGPC
Sbjct: 121 IKQPTVKLHGNKDSICKPCHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQLAVRCEGPC 180
Query: 181 PCPTEQAATSTADGKPETCTGQDLADLGDRLRDWFQLLHENSKQNGSASSVAGPASGLDK 240
PCPTEQAATSTADGKPETCTGQDLADLGDRLRDWFQLLHENSKQNGSASSVAGPASGLDK
Sbjct: 181 PCPTEQAATSTADGKPETCTGQDLADLGDRLRDWFQLLHENSKQNGSASSVAGPASGLDK 240
Query: 241 SLGASCKDSIGWMFSKLDTSADLFLDQTELAAINLDKYEVCIRPFFNSCDTYKDGRVSTA 300
SLGASCKDSIGWMFSKLDTSADLFLDQTELAAINLDKYEVCIRPFFNSCDTYKDGRVSTA
Sbjct: 241 SLGASCKDSIGWMFSKLDTSADLFLDQTELAAINLDKYEVCIRPFFNSCDTYKDGRVSTA 300
Query: 301 EWCFCFWREKPPCLAELERIQIQEAAKKKPGIFIPSCDEDGYYRKMQCDQSSGDCWCVDQ 360
EWCFCFWREKPPCLAELERIQIQEAAKKKPGIFIPSCDEDGYYRKMQCDQSSGDCWCVDQ
Sbjct: 301 EWCFCFWREKPPCLAELERIQIQEAAKKKPGIFIPSCDEDGYYRKMQCDQSSGDCWCVDQ 360
Query: 361 LGLELTGTRTHGSPDCDDIVGFSGDFGSGVGWEDEEEKETEEAGEEAEEEEGEAGEADDG 420
LGLELTGTRTHGSPDCDDIVGFSGDFGSGVGWEDEEEKETEEAGEEAEEEEGEAGEADDG
Sbjct: 361 LGLELTGTRTHGSPDCDDIVGFSGDFGSGVGWEDEEEKETEEAGEEAEEEEGEAGEADDG 420
Query: 421 GYIW 424
GYIW
Sbjct: 421 GYIW 424
>gi|93141001 testican 3 isoform 2 [Homo sapiens]
Length = 436
Score = 414 bits (1064), Expect = e-116
Identities = 204/413 (49%), Positives = 272/413 (65%), Gaps = 13/413 (3%)
Query: 18 AAALAEGDAKGLKEGETPGNFMEDEQWLSSISQYSGKIKHWNRFRDEVEDDYIKSWEDNQ 77
AAA A A G +G GNF++D+QWL++ISQY ++ WN+FRDEVEDDY ++W +
Sbjct: 21 AAAAAVAAAGGRSDG---GNFLDDKQWLTTISQYDKEVGQWNKFRDEVEDDYFRTWSPGK 77
Query: 78 QGDEALDTTKDPCQKVKCSRHKVCIAQGYQRAMCISRKKLEHRIKQPTV---KLHGNKDS 134
D+ALD KDPC K+KCSRHKVCIAQ Q A+CIS ++L HR+K+ V + G S
Sbjct: 78 PFDQALDPAKDPCLKMKCSRHKVCIAQDSQTAVCISHRRLTHRMKEAGVDHRQWRGPILS 137
Query: 135 ICKPCHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQLAVRCEGPCPCPTEQAATSTADG 194
CK C + + VCGSDGHTYS CKLE QAC+ KQ++V+CEG CPCP+++ TST+
Sbjct: 138 TCKQCPVVYPSPVCGSDGHTYSFQCKLEYQACVLGKQISVKCEGHCPCPSDK-PTSTSRN 196
Query: 195 KPETCTGQDLADLGDRLRDWFQLLHENSKQNGSASSVAGP-ASGLDKSLGASCKDSIGWM 253
C+ + ++ +RLRDWF+ LHE+ QN ++ P S D S+ CKDS+GWM
Sbjct: 197 VKRACSDLEFREVANRLRDWFKALHESGSQNKKTKTLLRPERSRFDTSILPICKDSLGWM 256
Query: 254 FSKLDTSADLFLDQTELAAINLDKYEVCIRPFFNSCDTYKDGRVSTAEWCFCFWREK-PP 312
F++LDT+ DL LDQ+EL +I LDK E C + FFNSCDTYKD +S EWC+CF R++ PP
Sbjct: 257 FNRLDTNYDLLLDQSELRSIYLDKNEQCTKAFFNSCDTYKDSLISNNEWCYCFQRQQDPP 316
Query: 313 CLAELERIQIQEAAKKKPGIFIPSCDEDGYYRKMQCDQSSGDCWCVDQLGLELTGTRTHG 372
C EL IQ ++ KK G +IP CDEDGYY+ QC S G CWCVD+ G E+ G+R +G
Sbjct: 317 CQTELSNIQKRQGVKKLLGQYIPLCDEDGYYKPTQCHGSVGQCWCVDRYGNEVMGSRING 376
Query: 373 SPDCDDIVGFSGDFGSG--VGWEDEEEKETE--EAGEEAEEEEGEAGEADDGG 421
DC SGDF SG W D+E+ E + +E E+++ + G+ DDGG
Sbjct: 377 VADCAIDFEISGDFASGDFHEWTDDEDDEDDIMNDEDEIEDDDEDEGDDDDGG 429
>gi|93141003 testican 3 isoform 1 [Homo sapiens]
Length = 433
Score = 403 bits (1036), Expect = e-112
Identities = 201/413 (48%), Positives = 269/413 (65%), Gaps = 16/413 (3%)
Query: 18 AAALAEGDAKGLKEGETPGNFMEDEQWLSSISQYSGKIKHWNRFRDEVEDDYIKSWEDNQ 77
AAA A A G +G GNF++D+QWL++ISQY ++ WN+FRD DDY ++W +
Sbjct: 21 AAAAAVAAAGGRSDG---GNFLDDKQWLTTISQYDKEVGQWNKFRD---DDYFRTWSPGK 74
Query: 78 QGDEALDTTKDPCQKVKCSRHKVCIAQGYQRAMCISRKKLEHRIKQPTV---KLHGNKDS 134
D+ALD KDPC K+KCSRHKVCIAQ Q A+CIS ++L HR+K+ V + G S
Sbjct: 75 PFDQALDPAKDPCLKMKCSRHKVCIAQDSQTAVCISHRRLTHRMKEAGVDHRQWRGPILS 134
Query: 135 ICKPCHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQLAVRCEGPCPCPTEQAATSTADG 194
CK C + + VCGSDGHTYS CKLE QAC+ KQ++V+CEG CPCP+++ TST+
Sbjct: 135 TCKQCPVVYPSPVCGSDGHTYSFQCKLEYQACVLGKQISVKCEGHCPCPSDKP-TSTSRN 193
Query: 195 KPETCTGQDLADLGDRLRDWFQLLHENSKQNGSASSVAGPA-SGLDKSLGASCKDSIGWM 253
C+ + ++ +RLRDWF+ LHE+ QN ++ P S D S+ CKDS+GWM
Sbjct: 194 VKRACSDLEFREVANRLRDWFKALHESGSQNKKTKTLLRPERSRFDTSILPICKDSLGWM 253
Query: 254 FSKLDTSADLFLDQTELAAINLDKYEVCIRPFFNSCDTYKDGRVSTAEWCFCFWREK-PP 312
F++LDT+ DL LDQ+EL +I LDK E C + FFNSCDTYKD +S EWC+CF R++ PP
Sbjct: 254 FNRLDTNYDLLLDQSELRSIYLDKNEQCTKAFFNSCDTYKDSLISNNEWCYCFQRQQDPP 313
Query: 313 CLAELERIQIQEAAKKKPGIFIPSCDEDGYYRKMQCDQSSGDCWCVDQLGLELTGTRTHG 372
C EL IQ ++ KK G +IP CDEDGYY+ QC S G CWCVD+ G E+ G+R +G
Sbjct: 314 CQTELSNIQKRQGVKKLLGQYIPLCDEDGYYKPTQCHGSVGQCWCVDRYGNEVMGSRING 373
Query: 373 SPDCDDIVGFSGDFGSG--VGWEDEEEKETE--EAGEEAEEEEGEAGEADDGG 421
DC SGDF SG W D+E+ E + +E E+++ + G+ DDGG
Sbjct: 374 VADCAIDFEISGDFASGDFHEWTDDEDDEDDIMNDEDEIEDDDEDEGDDDDGG 426
>gi|4759164 sparc/osteonectin, cwcv and kazal-like domains
proteoglycan 1 precursor [Homo sapiens]
Length = 439
Score = 375 bits (963), Expect = e-104
Identities = 202/445 (45%), Positives = 269/445 (60%), Gaps = 42/445 (9%)
Query: 13 LLLLAAAALA---------EGDAKGLKEGETPGNFMEDEQWLSSISQYSGKIKHWNRFRD 63
+ +LAAAA A DA G GNF++++QWLS++SQY + K+WNRFRD
Sbjct: 4 IAVLAAAAAAWCFLQVESRHLDALAGGAGPNHGNFLDNDQWLSTVSQYD-RDKYWNRFRD 62
Query: 64 EVEDDYIKSWEDNQQGDEALDTTKDPCQKVKCSRHKVCIAQGYQRAMCISRKKLEHRIKQ 123
DDY ++W N+ D+ALD +KDPC KVKCS HKVC+ Q YQ A+C+SRK L R K+
Sbjct: 63 ---DDYFRNWNPNKPFDQALDPSKDPCLKVKCSPHKVCVTQDYQTALCVSRKHLLPRQKK 119
Query: 124 PTVKLH---GNKDSI-CKPCHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQLAVRCEGP 179
V G + + CKPC +AQ A VCGSDGH+Y+S CKLE AC + K LA C+GP
Sbjct: 120 GNVAQKHWVGPSNLVKCKPCPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGP 179
Query: 180 CPCPTEQAATSTADGKPETCTGQDLADLGDRLRDWFQLLHENSKQNGSASSVAGPASGLD 239
CPC E + CT ++L +L RL+DWF LHE++ + +S D
Sbjct: 180 CPCLPEPEPPKHK-AERSACTDKELRNLASRLKDWFGALHEDANRVIKPTSSNTAQGRFD 238
Query: 240 KSLGASCKDSIGWMFSKLDTSADLFLDQTELAAINLDKYEVCIRPFFNSCDTYKDGRVST 299
S+ CKDS+GWMF+KLD + DL LD +E+ AI LDKYE CI+P FNSCD++KDG++S
Sbjct: 239 TSILPICKDSLGWMFNKLDMNYDLLLDPSEINAIYLDKYEPCIKPLFNSCDSFKDGKLSN 298
Query: 300 AEWCFCFWREKP---PCLAELERIQIQEAAKKKPGIFIPSCDEDGYYRKMQCDQSSGDCW 356
EWC+CF +KP PC E+ RIQ K G FIP C+E+GYY+ QC S+G CW
Sbjct: 299 NEWCYCF--QKPGGLPCQNEMNRIQKLSKGKSLLGAFIPRCNEEGYYKATQCHGSTGQCW 356
Query: 357 CVDQLGLELTGTRTHGSPDCDDIVGFSGDFGSG--------------VGWEDEEEK---E 399
CVD+ G EL G+R G+ C++ SGDFGSG +G +D+E K
Sbjct: 357 CVDKYGNELAGSRKQGAVSCEEEQETSGDFGSGGSVVLLDDLEYERELGPKDKEGKLRVH 416
Query: 400 TEEAGEEAEEEEGEAGEADDGGYIW 424
T E+ E+E+ + + D+ GYIW
Sbjct: 417 TRAVTEDDEDEDDD--KEDEVGYIW 439
>gi|197313714 sparc/osteonectin, cwcv and kazal-like domains
proteoglycan (testican) 2 isoform 1 [Homo sapiens]
Length = 77
Score = 133 bits (335), Expect = 3e-31
Identities = 64/68 (94%), Positives = 64/68 (94%)
Query: 1 MRAPGCGRLVLPLLLLAAAALAEGDAKGLKEGETPGNFMEDEQWLSSISQYSGKIKHWNR 60
MRAPGCGRLVLPLLLLAAAALAEGDAKGLKEGETPGNFMEDEQWLSSISQYSGKIKHWNR
Sbjct: 1 MRAPGCGRLVLPLLLLAAAALAEGDAKGLKEGETPGNFMEDEQWLSSISQYSGKIKHWNR 60
Query: 61 FRDEVEDD 68
FRD D
Sbjct: 61 FRDVPSSD 68
>gi|190194423 SPARC-like 1 [Homo sapiens]
Length = 664
Score = 60.8 bits (146), Expect = 2e-09
Identities = 65/248 (26%), Positives = 86/248 (34%), Gaps = 56/248 (22%)
Query: 88 DPCQKVKCSRHKVCIAQGYQRAMCISRKKLEHRIKQPTVKLHGNKDSICKPCHMAQLASV 147
D C +C R +C A + C+ + + C P L V
Sbjct: 431 DSCMSFQCKRGHICKADQQGKPHCVCQDPVT-----------------CPPTK--PLDQV 471
Query: 148 CGSDGHTYSSVCKLEQQACLSSKQLAVRCEGPCPCPTEQAATSTADGKPETCTGQDLADL 207
CG+D TY+S C L C R EG Q A TCT ++
Sbjct: 472 CGTDNQTYASSCHLFATKC--------RLEGTKKGHQLQLDYFGACKSIPTCTDFEVIQF 523
Query: 208 GDRLRDWF-----QLLHENS--------KQNGSASSVAGPASGL---DKSLGASCKD--- 248
R+RDW QL NS KQ + L D + +D
Sbjct: 524 PLRMRDWLKNILMQLYEANSEHAGYLNEKQRNKVKKIYLDEKRLLAGDHPIDLLLRDFKK 583
Query: 249 -------SIGWMFSKLDTSA-DLFLDQTELAAI--NLDKYEVCIRPFFNSCDTYKDGRVS 298
+ W FS+LD D L +ELA + +L E CI FF CD KD ++
Sbjct: 584 NYHMYVYPVHWQFSELDQHPMDRVLTHSELAPLRASLVPMEHCITRFFEECDPNKDKHIT 643
Query: 299 TAEWCFCF 306
EW CF
Sbjct: 644 LKEWGHCF 651
>gi|190341024 SPARC-like 1 [Homo sapiens]
Length = 664
Score = 60.8 bits (146), Expect = 2e-09
Identities = 65/248 (26%), Positives = 86/248 (34%), Gaps = 56/248 (22%)
Query: 88 DPCQKVKCSRHKVCIAQGYQRAMCISRKKLEHRIKQPTVKLHGNKDSICKPCHMAQLASV 147
D C +C R +C A + C+ + + C P L V
Sbjct: 431 DSCMSFQCKRGHICKADQQGKPHCVCQDPVT-----------------CPPTK--PLDQV 471
Query: 148 CGSDGHTYSSVCKLEQQACLSSKQLAVRCEGPCPCPTEQAATSTADGKPETCTGQDLADL 207
CG+D TY+S C L C R EG Q A TCT ++
Sbjct: 472 CGTDNQTYASSCHLFATKC--------RLEGTKKGHQLQLDYFGACKSIPTCTDFEVIQF 523
Query: 208 GDRLRDWF-----QLLHENS--------KQNGSASSVAGPASGL---DKSLGASCKD--- 248
R+RDW QL NS KQ + L D + +D
Sbjct: 524 PLRMRDWLKNILMQLYEANSEHAGYLNEKQRNKVKKIYLDEKRLLAGDHPIDLLLRDFKK 583
Query: 249 -------SIGWMFSKLDTSA-DLFLDQTELAAI--NLDKYEVCIRPFFNSCDTYKDGRVS 298
+ W FS+LD D L +ELA + +L E CI FF CD KD ++
Sbjct: 584 NYHMYVYPVHWQFSELDQHPMDRVLTHSELAPLRASLVPMEHCITRFFEECDPNKDKHIT 643
Query: 299 TAEWCFCF 306
EW CF
Sbjct: 644 LKEWGHCF 651
>gi|115298674 nidogen 1 precursor [Homo sapiens]
Length = 1247
Score = 59.7 bits (143), Expect = 5e-09
Identities = 32/75 (42%), Positives = 39/75 (52%), Gaps = 7/75 (9%)
Query: 309 EKPPCLAELERIQIQEAAKKK-----PGIFIPSCDEDGYYRKMQCDQSSGDCWCVDQLGL 363
EK C E E I A PG+F+P CD G+Y QC S+G CWCVD+ G
Sbjct: 845 EKTRCQHEREHILGAAGATDPQRPIPPGLFVPECDAHGHYAPTQCHGSTGYCWCVDRDGR 904
Query: 364 ELTGTRTHG--SPDC 376
E+ GTRT +P C
Sbjct: 905 EVEGTRTRPGMTPPC 919
>gi|68448544 CD74 antigen isoform a [Homo sapiens]
Length = 296
Score = 56.2 bits (134), Expect = 5e-08
Identities = 29/83 (34%), Positives = 42/83 (50%), Gaps = 1/83 (1%)
Query: 309 EKPPCLAELERIQIQEAAKKKPGIFIPSCDEDGYYRKMQCDQSSGDCWCVDQLGLELTGT 368
+ PP + + ++ PG F P CDE+G Y +QC S G CWCV G E+ T
Sbjct: 204 DAPPKVLTKCQEEVSHIPAVHPGSFRPKCDENGNYLPLQCYGSIGYCWCVFPNGTEVPNT 263
Query: 369 RTHGSPDCDDIVGFSGDFGSGVG 391
R+ G +C + + D SG+G
Sbjct: 264 RSRGHHNCSESLELE-DPSSGLG 285
>gi|24308277 SPARC related modular calcium binding 2 [Homo sapiens]
Length = 457
Score = 56.2 bits (134), Expect = 5e-08
Identities = 33/99 (33%), Positives = 53/99 (53%), Gaps = 8/99 (8%)
Query: 283 RPFFNSCDTY----KDGRVSTAEWCFCFWREKPPCLAELERIQIQEAAKKKPGIFIPSCD 338
R F + C+ KD ++ A C ++ C+AE + Q ++A K+ +FIP C+
Sbjct: 58 RTFLSRCEFQRAKCKDPQLEIAYRGNC--KDVSRCVAERKYTQ-EQARKEFQQVFIPECN 114
Query: 339 EDGYYRKMQCDQSSGDCWCVDQLGLELTGTR-THGSPDC 376
+DG Y ++QC +G CWCV G ++GT H +P C
Sbjct: 115 DDGTYSQVQCHSYTGYCWCVTPNGRPISGTAVAHKTPRC 153
Score = 44.7 bits (104), Expect = 2e-04
Identities = 23/60 (38%), Positives = 33/60 (55%), Gaps = 3/60 (5%)
Query: 322 IQEAAK-KKPGIFIPSCDEDGYYRKMQCDQSSGDCWCV-DQLGLELTGTRT-HGSPDCDD 378
++EA + K + IP C G Y+ +QC S+G CWCV G + GT T + P CD+
Sbjct: 235 LEEAKQPKNDNVVIPECAHGGLYKPVQCHPSTGYCWCVLVDTGRPIPGTSTRYEQPKCDN 294
Score = 30.4 bits (67), Expect = 3.2
Identities = 16/56 (28%), Positives = 27/56 (48%), Gaps = 2/56 (3%)
Query: 126 VKLHGNKDSICK-PCHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQLAVRCEGPC 180
+++ +KD C C + +C SDG T+ S C+ ++ C QL + G C
Sbjct: 30 LRVDQDKDKDCSLDCAGSPQKPLCASDGRTFLSRCEFQRAKC-KDPQLEIAYRGNC 84
>gi|4507171 secreted protein, acidic, cysteine-rich [Homo sapiens]
Length = 303
Score = 55.1 bits (131), Expect = 1e-07
Identities = 59/271 (21%), Positives = 88/271 (32%), Gaps = 66/271 (24%)
Query: 70 IKSWEDNQQGDEALDTTKDPCQKVKCSRHKVCIAQGYQRAMCISRKKLEHRIKQPTVKLH 129
+ ++D + E ++PCQ C KVC MC+ +
Sbjct: 52 VGEFDDGAEETEEEVVAENPCQNHHCKHGKVCELDENNTPMCVCQ--------------- 96
Query: 130 GNKDSICKPCHMAQLASVCGSDGHTYSSVCKLEQQACL-----SSKQLAVRCEGPCPCPT 184
D P + + VC +D T+ S C C +L + GPC
Sbjct: 97 ---DPTSCPAPIGEFEKVCSNDNKTFDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIP 153
Query: 185 EQAATSTADGKPETCTGQDLADLGDRLRDWFQ-------------------------LLH 219
C +L + R+RDW + +H
Sbjct: 154 P-------------CLDSELTEFPLRMRDWLKNVLVTLYERDEDNNLLTEKQKLRVKKIH 200
Query: 220 ENSKQ-NGSASSVAGPASGLDKSLGASCKDSIGWMFSKLDTSA-DLFLDQTELAAIN--L 275
EN K+ V A +K+ + W F +LD D +L TELA + L
Sbjct: 201 ENEKRLEAGDHPVELLARDFEKNYNMYIFP-VHWQFGQLDQHPIDGYLSHTELAPLRAPL 259
Query: 276 DKYEVCIRPFFNSCDTYKDGRVSTAEWCFCF 306
E C FF +CD D ++ EW CF
Sbjct: 260 IPMEHCTTRFFETCDLDNDKYIALDEWAGCF 290
>gi|11321593 insulin-like growth factor binding protein 6 [Homo
sapiens]
Length = 240
Score = 54.7 bits (130), Expect = 2e-07
Identities = 29/76 (38%), Positives = 42/76 (55%), Gaps = 8/76 (10%)
Query: 309 EKPPCLAELERI--QIQ-EAAKKKPGIFIPSCDEDGYYRKMQCDQSSGD----CWCVDQL 361
E PC L+ + Q+Q E + +++P+CD G+YRK QC S G CWCVD++
Sbjct: 159 EMGPCRRHLDSVLQQLQTEVYRGAQTLYVPNCDHRGFYRKRQCRSSQGQRRGPCWCVDRM 218
Query: 362 GLELTGTRT-HGSPDC 376
G L G+ +GS C
Sbjct: 219 GKSLPGSPDGNGSSSC 234
>gi|78190498 secreted modular calcium-binding protein 1 isoform 1
[Homo sapiens]
Length = 435
Score = 53.1 bits (126), Expect = 5e-07
Identities = 70/281 (24%), Positives = 111/281 (39%), Gaps = 36/281 (12%)
Query: 119 HRIKQPTVKLHGNKDSICK-PCHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQLAV--- 174
HR P L ++D C C Q +C SDG +Y S+C+ ++ C V
Sbjct: 27 HRTTGPRF-LISDRDPQCNLHCSRTQPKPICASDGRSYESMCEYQRAKCRDPTLGVVHRG 85
Query: 175 RCE--GPCPCPTEQAATSTADGKPETCT-----GQDLADLGDRLRDW----FQLLHENSK 223
RC+ G C E+A KP+ G+D + + + + + +
Sbjct: 86 RCKDAGQSKCRLERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKP 145
Query: 224 QNGSASSVAGP---ASGLDKSL--GASCKDSIGWMFSKLDTSADLFLDQTELAAINLDKY 278
+GS+ P S DK L G S + G + + +F D E+ A L
Sbjct: 146 ISGSSVQNKTPVCSGSVTDKPLSQGNSGRKDDGSKPTPTMETQPVF-DGDEITAPTLWIK 204
Query: 279 EVCIRPFFNSCDTYKDGRVSTAEWCFCFWREKPPCLAELERIQIQEAAKKKPGIFIPSCD 338
+ I+ + + +E + +E+ L E ++ + GI IP C
Sbjct: 205 HLVIKD-----SKLNNTNIRNSEKVYSCDQERQSALEEAQQ-------NPREGIVIPECA 252
Query: 339 EDGYYRKMQCDQSSGDCWCV-DQLGLELTGTRT-HGSPDCD 377
G Y+ +QC QS+G CWCV G L GT T + P C+
Sbjct: 253 PGGLYKPVQCHQSTGYCWCVLVDTGRPLPGTSTRYVMPSCE 293
Score = 52.8 bits (125), Expect = 6e-07
Identities = 30/86 (34%), Positives = 43/86 (50%), Gaps = 2/86 (2%)
Query: 317 LERIQIQEAAKK-KPGIFIPSCDEDGYYRKMQCDQSSGDCWCVDQLGLELTGTRTHG-SP 374
LER Q E AKK + +F+P C EDG + ++QC +G CWCV G ++G+ +P
Sbjct: 97 LERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTP 156
Query: 375 DCDDIVGFSGDFGSGVGWEDEEEKET 400
C V G +D+ K T
Sbjct: 157 VCSGSVTDKPLSQGNSGRKDDGSKPT 182
Score = 33.9 bits (76), Expect = 0.29
Identities = 35/148 (23%), Positives = 60/148 (40%), Gaps = 17/148 (11%)
Query: 168 SSKQLAVRCEGPCPCPTEQAATSTAD----GKPETCTGQDLADLGDRLR-DWFQLLHENS 222
S++ + CE T +A D G PE + + L D L D Q ++ +
Sbjct: 284 STRYVMPSCESDARAKTTEADDPFKDRELPGCPEGKKMEFITSLLDALTTDMVQAINSAA 343
Query: 223 KQNGSASSVAGPASGLDKSLGASCKDSIGWMFSKLDTSADLFLDQTELAAINL-----DK 277
G S P+ L++ + + W FS+LD+++ +++ E+ K
Sbjct: 344 PTGGGRFSEPDPSHTLEERV-------VHWYFSQLDSNSSNDINKREMKPFKRYVKKKAK 396
Query: 278 YEVCIRPFFNSCDTYKDGRVSTAEWCFC 305
+ C R F + CD KD +S E C
Sbjct: 397 PKKCARRFTDYCDLNKDKVISLPELKGC 424
>gi|11545873 secreted modular calcium-binding protein 1 isoform 2
[Homo sapiens]
Length = 434
Score = 53.1 bits (126), Expect = 5e-07
Identities = 70/281 (24%), Positives = 111/281 (39%), Gaps = 36/281 (12%)
Query: 119 HRIKQPTVKLHGNKDSICK-PCHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQLAV--- 174
HR P L ++D C C Q +C SDG +Y S+C+ ++ C V
Sbjct: 27 HRTTGPRF-LISDRDPQCNLHCSRTQPKPICASDGRSYESMCEYQRAKCRDPTLGVVHRG 85
Query: 175 RCE--GPCPCPTEQAATSTADGKPETCT-----GQDLADLGDRLRDW----FQLLHENSK 223
RC+ G C E+A KP+ G+D + + + + + +
Sbjct: 86 RCKDAGQSKCRLERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKP 145
Query: 224 QNGSASSVAGP---ASGLDKSL--GASCKDSIGWMFSKLDTSADLFLDQTELAAINLDKY 278
+GS+ P S DK L G S + G + + +F D E+ A L
Sbjct: 146 ISGSSVQNKTPVCSGSVTDKPLSQGNSGRKDDGSKPTPTMETQPVF-DGDEITAPTLWIK 204
Query: 279 EVCIRPFFNSCDTYKDGRVSTAEWCFCFWREKPPCLAELERIQIQEAAKKKPGIFIPSCD 338
+ I+ + + +E + +E+ L E ++ + GI IP C
Sbjct: 205 HLVIKD-----SKLNNTNIRNSEKVYSCDQERQSALEEAQQ-------NPREGIVIPECA 252
Query: 339 EDGYYRKMQCDQSSGDCWCV-DQLGLELTGTRT-HGSPDCD 377
G Y+ +QC QS+G CWCV G L GT T + P C+
Sbjct: 253 PGGLYKPVQCHQSTGYCWCVLVDTGRPLPGTSTRYVMPSCE 293
Score = 52.8 bits (125), Expect = 6e-07
Identities = 30/86 (34%), Positives = 43/86 (50%), Gaps = 2/86 (2%)
Query: 317 LERIQIQEAAKK-KPGIFIPSCDEDGYYRKMQCDQSSGDCWCVDQLGLELTGTRTHG-SP 374
LER Q E AKK + +F+P C EDG + ++QC +G CWCV G ++G+ +P
Sbjct: 97 LERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTP 156
Query: 375 DCDDIVGFSGDFGSGVGWEDEEEKET 400
C V G +D+ K T
Sbjct: 157 VCSGSVTDKPLSQGNSGRKDDGSKPT 182
Score = 33.9 bits (76), Expect = 0.29
Identities = 35/148 (23%), Positives = 60/148 (40%), Gaps = 17/148 (11%)
Query: 168 SSKQLAVRCEGPCPCPTEQAATSTAD----GKPETCTGQDLADLGDRLR-DWFQLLHENS 222
S++ + CE T +A D G PE + + L D L D Q ++ +
Sbjct: 284 STRYVMPSCESDARAKTTEADDPFKDRELPGCPEGKKMEFITSLLDALTTDMVQAINSAA 343
Query: 223 KQNGSASSVAGPASGLDKSLGASCKDSIGWMFSKLDTSADLFLDQTELAAINL-----DK 277
G S P+ L++ + + W FS+LD+++ +++ E+ K
Sbjct: 344 PTGGGRFSEPDPSHTLEERV-------VHWYFSQLDSNSSNDINKREMKPFKRYVKKKAK 396
Query: 278 YEVCIRPFFNSCDTYKDGRVSTAEWCFC 305
+ C R F + CD KD +S E C
Sbjct: 397 PKKCARRFTDYCDLNKDKVISLPELKGC 424
>gi|62243068 insulin-like growth factor binding protein 3 isoform b
precursor [Homo sapiens]
Length = 291
Score = 52.4 bits (124), Expect = 8e-07
Identities = 23/49 (46%), Positives = 29/49 (59%), Gaps = 4/49 (8%)
Query: 331 GIFIPSCDEDGYYRKMQCDQSSGD----CWCVDQLGLELTGTRTHGSPD 375
G+ IP+CD+ G+Y+K QC S G CWCVD+ G L G T G D
Sbjct: 234 GVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKED 282
>gi|62243248 insulin-like growth factor binding protein 3 isoform a
precursor [Homo sapiens]
Length = 297
Score = 52.4 bits (124), Expect = 8e-07
Identities = 23/49 (46%), Positives = 29/49 (59%), Gaps = 4/49 (8%)
Query: 331 GIFIPSCDEDGYYRKMQCDQSSGD----CWCVDQLGLELTGTRTHGSPD 375
G+ IP+CD+ G+Y+K QC S G CWCVD+ G L G T G D
Sbjct: 240 GVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKED 288
>gi|55770862 thyroglobulin [Homo sapiens]
Length = 2768
Score = 52.0 bits (123), Expect = 1e-06
Identities = 25/50 (50%), Positives = 33/50 (66%), Gaps = 3/50 (6%)
Query: 330 PGIFIPSCD-EDGYYRKMQCDQSSGDCWCVDQLGLELTGTR-THGSPDCD 377
PG ++P+C EDG + +QCDQ+ G CWCV G E+ GTR T G P C+
Sbjct: 1163 PG-YVPACRAEDGGFSPVQCDQAQGSCWCVMDSGEEVPGTRVTGGQPACE 1211
Score = 51.6 bits (122), Expect = 1e-06
Identities = 21/42 (50%), Positives = 28/42 (66%), Gaps = 1/42 (2%)
Query: 333 FIPSCDEDGYYRKMQCDQSSGDCWCVDQLGLELTGTRTHGSP 374
++PSC +G Y+ +QC Q+ G CWCVD G E+ GTR G P
Sbjct: 315 YVPSCRRNGDYQAVQC-QTEGPCWCVDAQGKEMHGTRQQGEP 355
Score = 50.8 bits (120), Expect = 2e-06
Identities = 21/62 (33%), Positives = 31/62 (50%)
Query: 313 CLAELERIQIQEAAKKKPGIFIPSCDEDGYYRKMQCDQSSGDCWCVDQLGLELTGTRTHG 372
C + ++I + ++P C + G Y +QCD CWCVD G+E+ GTR G
Sbjct: 96 CQLQKQQILLSGYINSTDTSYLPQCQDSGDYAPVQCDVQQVQCWCVDAEGMEVYGTRQLG 155
Query: 373 SP 374
P
Sbjct: 156 RP 157
Score = 50.1 bits (118), Expect = 4e-06
Identities = 25/63 (39%), Positives = 33/63 (52%), Gaps = 6/63 (9%)
Query: 312 PCLAELERIQIQEAAKKKPGIFIPSCDEDGYYRKMQCDQSSGDCWCVDQLGLELTGTRTH 371
PC EL+R E A K ++P C EDG ++ +QC CWCV G E+ G+R
Sbjct: 33 PC--ELQR----ETAFLKQADYVPQCAEDGSFQTVQCQNDGRSCWCVGANGSEVLGSRQP 86
Query: 372 GSP 374
G P
Sbjct: 87 GRP 89
Score = 50.1 bits (118), Expect = 4e-06
Identities = 24/62 (38%), Positives = 36/62 (58%), Gaps = 4/62 (6%)
Query: 317 LERIQIQEAAKKKPG-IFIPSCDEDGYYRKMQCDQSSGDCWCVDQLGLELTGTRTH-GSP 374
+E + + ++ P +F+PSC +G Y +QC SG+CWCV+ G EL G+R G P
Sbjct: 599 METVLSSQTCEQTPERLFVPSCTTEGSYEDVQC--FSGECWCVNSWGKELPGSRVRGGQP 656
Query: 375 DC 376
C
Sbjct: 657 RC 658
Score = 47.4 bits (111), Expect = 3e-05
Identities = 33/107 (30%), Positives = 52/107 (48%), Gaps = 21/107 (19%)
Query: 283 RPFFNSCDT---YKDGRVSTAE-WCFCFW-REKP-----------PCLAELERIQIQEAA 326
R F SC T Y+D + + E WC W +E P P E +R ++Q
Sbjct: 614 RLFVPSCTTEGSYEDVQCFSGECWCVNSWGKELPGSRVRGGQPRCPTDCEKQRARMQSLM 673
Query: 327 KKKPG---IFIPSCDEDGYYRKMQCDQSSGDCWCVDQLGLELTGTRT 370
+P +F+P+C +G++ +QC S +C+CVD G + GTR+
Sbjct: 674 GSQPAGSTLFVPACTSEGHFLPVQCFNS--ECYCVDAEGQAIPGTRS 718
Score = 46.2 bits (108), Expect = 6e-05
Identities = 30/105 (28%), Positives = 43/105 (40%), Gaps = 14/105 (13%)
Query: 325 AAKKKPGIFIPSCDEDGYYRKMQCDQSSGDCWCVDQLGLELTGTRTHGS---PDCDDIVG 381
+A + G ++P CD G + +QC +G CWCVD+ G + G+ T S P C
Sbjct: 1019 SALLRSGPYMPQCDAFGSWEPVQCHAGTGHCWCVDEKGGFIPGSLTARSLQIPQCPTTCE 1078
Query: 382 FSGDFGSGVGWEDEEEKETE-----------EAGEEAEEEEGEAG 415
S G W+ +E E GE A + AG
Sbjct: 1079 KSRTSGLLSSWKQARSQENPSPKDLFVPACLETGEYARLQASGAG 1123
Score = 33.1 bits (74), Expect = 0.49
Identities = 14/29 (48%), Positives = 18/29 (62%)
Query: 337 CDEDGYYRKMQCDQSSGDCWCVDQLGLEL 365
CD++G YR Q D+ SG +CVD G L
Sbjct: 1523 CDQNGQYRASQKDRGSGKAFCVDGEGRRL 1551
Score = 31.6 bits (70), Expect = 1.4
Identities = 19/66 (28%), Positives = 30/66 (45%), Gaps = 3/66 (4%)
Query: 314 LAELERIQIQEAAKKKPGIFIPSCDEDGYYRKMQCDQSSGDCWCVDQLGLELTGTRTHGS 373
L+ ++ + QE K +F+P+C E G Y ++Q S WCVD E + S
Sbjct: 1086 LSSWKQARSQENPSPKD-LFVPACLETGEYARLQA--SGAGTWCVDPASGEELRPGSSSS 1142
Query: 374 PDCDDI 379
C +
Sbjct: 1143 AQCPSL 1148
Score = 30.8 bits (68), Expect = 2.4
Identities = 13/25 (52%), Positives = 16/25 (64%), Gaps = 2/25 (8%)
Query: 354 DCWCVDQLGLELTGTRTHGS--PDC 376
+CWCVD+ G EL G R+ S P C
Sbjct: 897 NCWCVDEAGQELEGMRSEPSKLPTC 921
>gi|144953895 nidogen 2 precursor [Homo sapiens]
Length = 1375
Score = 50.8 bits (120), Expect = 2e-06
Identities = 27/61 (44%), Positives = 33/61 (54%), Gaps = 5/61 (8%)
Query: 312 PCLAELERIQIQEAAKKKPG--IFIPSCDEDGYYRKMQCDQSSGDCWCVDQLGLELTGTR 369
PC + Q Q A PG IP CDE G + +QC S+G CWCVD G E+ GT+
Sbjct: 939 PCEQQQRHAQAQYAY---PGARFHIPQCDEQGNFLPLQCHGSTGFCWCVDPDGHEVPGTQ 995
Query: 370 T 370
T
Sbjct: 996 T 996
Score = 49.3 bits (116), Expect = 7e-06
Identities = 22/64 (34%), Positives = 36/64 (56%), Gaps = 2/64 (3%)
Query: 309 EKPPCLAELERIQIQE--AAKKKPGIFIPSCDEDGYYRKMQCDQSSGDCWCVDQLGLELT 366
++PP + E R + E + ++P CD+ G++ +QC S CWCVD+ G E+
Sbjct: 1013 QRPPTICERWRENLLEHYGGTPRDDQYVPQCDDLGHFIPLQCHGKSDFCWCVDKDGREVQ 1072
Query: 367 GTRT 370
GTR+
Sbjct: 1073 GTRS 1076
>gi|10834982 insulin-like growth factor binding protein 5 [Homo
sapiens]
Length = 272
Score = 49.3 bits (116), Expect = 7e-06
Identities = 22/66 (33%), Positives = 39/66 (59%), Gaps = 7/66 (10%)
Query: 309 EKPPCLAELERI--QIQEAAKKKP-GIFIPSCDEDGYYRKMQCDQSSGD----CWCVDQL 361
E+ PC +E +++ + + P +++P+CD G+Y++ QC S G CWCVD+
Sbjct: 188 EQGPCRRHMEASLQELKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGICWCVDKY 247
Query: 362 GLELTG 367
G++L G
Sbjct: 248 GMKLPG 253
>gi|54873613 agrin [Homo sapiens]
Length = 2045
Score = 48.9 bits (115), Expect = 9e-06
Identities = 34/126 (26%), Positives = 50/126 (39%), Gaps = 33/126 (26%)
Query: 85 TTKDPCQKVKCSRHKVCI--AQGYQRAMCISRKKLEHRIKQPTVKLHGNKDSICKPCHMA 142
T D C+ + C VC A+G RA C+ +K PC
Sbjct: 167 TPPDACRGMLCGFGAVCEPNAEGPGRASCVCKKS---------------------PCPSV 205
Query: 143 QLASVCGSDGHTYSSVCKLEQQACLSSKQLAVRCEGPC---------PCPTEQAATSTAD 193
+A VCGSD TYS+ C+L++ C +++ + GPC C +AD
Sbjct: 206 -VAPVCGSDASTYSNECELQRAQCSQQRRIRLLSRGPCGSRDPCSNVTCSFGSTCARSAD 264
Query: 194 GKPETC 199
G +C
Sbjct: 265 GLTASC 270
Score = 47.0 bits (110), Expect = 3e-05
Identities = 20/46 (43%), Positives = 24/46 (52%)
Query: 135 ICKPCHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQLAVRCEGPC 180
+C C VCGSDG TY S C+L + ACL Q+ GPC
Sbjct: 619 VCPRCEHPPPGPVCGSDGVTYGSACELREAACLQQTQIEEARAGPC 664
Score = 45.4 bits (106), Expect = 1e-04
Identities = 26/78 (33%), Positives = 37/78 (47%), Gaps = 9/78 (11%)
Query: 126 VKLHGNKDSICK--PCHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQLAVRCEGPC--- 180
V+ G+ +C C A VCGSDG TY + C+L+ AC Q++++ GPC
Sbjct: 913 VEESGSAHCVCPMLTCPEANATKVCGSDGVTYGNECQLKTIACRQGLQISIQSLGPCQEA 972
Query: 181 ----PCPTEQAATSTADG 194
PT + T T G
Sbjct: 973 VAPSTHPTSASVTVTTPG 990
Score = 44.3 bits (103), Expect = 2e-04
Identities = 18/34 (52%), Positives = 23/34 (67%)
Query: 147 VCGSDGHTYSSVCKLEQQACLSSKQLAVRCEGPC 180
VCGSDG TY S C+LE AC +++ V +GPC
Sbjct: 501 VCGSDGVTYGSACELEATACTLGREIQVARKGPC 534
Score = 43.9 bits (102), Expect = 3e-04
Identities = 21/46 (45%), Positives = 23/46 (50%)
Query: 135 ICKPCHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQLAVRCEGPC 180
+C +A VCGSDGHTY S C L AC L V GPC
Sbjct: 554 VCPSECVALAQPVCGSDGHTYPSECMLHVHACTHQISLHVASAGPC 599
Score = 43.9 bits (102), Expect = 3e-04
Identities = 20/46 (43%), Positives = 27/46 (58%)
Query: 139 CHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQLAVRCEGPCPCPT 184
C + VCGSDG TYS+ C+L++ C S + L V +G C PT
Sbjct: 709 CQSVPGSPVCGSDGVTYSTECELKKARCESQRGLYVAAQGACRGPT 754
Score = 41.6 bits (96), Expect = 0.001
Identities = 29/100 (29%), Positives = 40/100 (40%), Gaps = 26/100 (26%)
Query: 86 TKDPCQKVKCSRHKVCI--AQGYQRAMCISRKKLEHRIKQPTVKLHGNKDSICKPCHMAQ 143
++DPC V CS C A G A C+ C A
Sbjct: 244 SRDPCSNVTCSFGSTCARSADGLT-ASCLCPAT----------------------CRGAP 280
Query: 144 LASVCGSDGHTYSSVCKLEQQACLSSKQLAVRCEGPC-PC 182
+VCGSDG Y C+L ++AC + + + +GPC PC
Sbjct: 281 EGTVCGSDGADYPGECQLLRRACARQENVFKKFDGPCDPC 320
Score = 35.0 bits (79), Expect = 0.13
Identities = 17/47 (36%), Positives = 22/47 (46%), Gaps = 5/47 (10%)
Query: 147 VCGSDGHTYSSVCKLEQQACLSSKQLAVRCEGPC-----PCPTEQAA 188
VC DG TY S C +Q C + + + +GPC PC Q A
Sbjct: 428 VCAQDGRTYDSDCWRQQAECRQQRAIPSKHQGPCDQAPSPCLGVQCA 474
Score = 33.1 bits (74), Expect = 0.49
Identities = 34/129 (26%), Positives = 50/129 (38%), Gaps = 24/129 (18%)
Query: 142 AQLASVCGSDGHTYSSVCKLEQ----QACLSSKQLAVRCEGPCPCPTE---QAATSTADG 194
A+ A VCG DG TY + C + + + L K + +C+G CP A + G
Sbjct: 351 ARQAPVCGDDGVTYENDCVMGRSGAARGLLLQKVRSGQCQGRDQCPEPCRFNAVCLSRRG 410
Query: 195 KPE------TCTG-------QD----LADLGDRLRDWFQLLHENSKQNGSASSVAGPASG 237
+P TC G QD +D + + Q SK G P G
Sbjct: 411 RPRCSCDRVTCDGAYRPVCAQDGRTYDSDCWRQQAECRQQRAIPSKHQGPCDQAPSPCLG 470
Query: 238 LDKSLGASC 246
+ + GA+C
Sbjct: 471 VQCAFGATC 479
>gi|5901956 follistatin-like 1 precursor [Homo sapiens]
Length = 308
Score = 47.4 bits (111), Expect = 3e-05
Identities = 56/241 (23%), Positives = 91/241 (37%), Gaps = 51/241 (21%)
Query: 78 QGDEALDTTKDPCQKVKCSRHKVCIA--QGYQRAMCISRKKLEHRIKQPTVKLHGNKDSI 135
+ +E L + C V C + C +G +CI +
Sbjct: 19 RAEEELRSKSKICANVFCGAGRECAVTEKGEPTCLCIEQ--------------------- 57
Query: 136 CKPCHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQLAVRCEGPCPCPTEQAATSTADGK 195
CKP VCGS+G TY + C+L + ACL+ ++ V +G C ++ + +
Sbjct: 58 CKP----HKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHC----KEKKSVSPSAS 109
Query: 196 PETCTGQDLADLGDRLRDWFQLLHENSKQNGSASSVAGPASGLDKSLGASCKDSIGWMFS 255
P C + +L R+ W L +G S + + LDK S
Sbjct: 110 PVVCYQSNRDELRRRIIQW---LEAEIIPDGWFSKGSNYSEILDKYFKNFDNGD-----S 161
Query: 256 KLDTSADL-FLDQTELAAINLDKYE----------VCIRPFFNSCDTYKDGRVSTAEWCF 304
+LD+S L F++Q E AIN+ Y +C+ D D ++S E+
Sbjct: 162 RLDSSEFLKFVEQNE-TAINITTYPDQENNKLLRGLCVDALIELSDENADWKLSFQEFLK 220
Query: 305 C 305
C
Sbjct: 221 C 221
>gi|4504615 insulin-like growth factor binding protein 1 precursor
[Homo sapiens]
Length = 259
Score = 43.1 bits (100), Expect = 5e-04
Identities = 26/80 (32%), Positives = 41/80 (51%), Gaps = 18/80 (22%)
Query: 307 WREKPPCLAELERIQIQEAAKKKPG-------IFIPSCDEDGYYRKMQCDQS----SGDC 355
W+E PC EL R+ ++ AK + ++P+C+++G+Y QC+ S +G C
Sbjct: 172 WKE--PCRIELYRV-VESLAKAQETSGEEISKFYLPNCNKNGFYHSRQCETSMDGEAGLC 228
Query: 356 WCVDQLGLELTGTRTHGSPD 375
WCV G R GSP+
Sbjct: 229 WCV----YPWNGKRIPGSPE 244
>gi|5453652 follistatin isoform FST317 precursor [Homo sapiens]
Length = 317
Score = 42.7 bits (99), Expect = 6e-04
Identities = 26/95 (27%), Positives = 38/95 (40%), Gaps = 21/95 (22%)
Query: 87 KDPCQKVKCSRHKVCIAQGYQRAMCISRKKLEHRIKQPTVKLHGNKDSIC-KPCHMAQLA 145
K C+ V C C+ A C++ + IC +P Q
Sbjct: 165 KKTCRDVFCPGSSTCVVDQTNNAYCVTCNR------------------ICPEPASSEQY- 205
Query: 146 SVCGSDGHTYSSVCKLEQQACLSSKQLAVRCEGPC 180
+CG+DG TYSS C L + CL + + + EG C
Sbjct: 206 -LCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKC 239
Score = 38.5 bits (88), Expect = 0.012
Identities = 27/120 (22%), Positives = 42/120 (35%), Gaps = 25/120 (20%)
Query: 63 DEVEDDYIKSWEDNQQGDEALDTTKDPCQKVKCSRHKVCIAQGYQRAMCISRKKLEHRIK 122
++V D+ + W G K+ C+ V C K C + C+
Sbjct: 68 EDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCGPGKKCRMNKKNKPRCV---------- 117
Query: 123 QPTVKLHGNKDSICKP--CHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQLAVRCEGPC 180
C P ++ VCG DG TY + C L + C +L V+ +G C
Sbjct: 118 -------------CAPDCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGRC 164
Score = 35.0 bits (79), Expect = 0.13
Identities = 15/34 (44%), Positives = 20/34 (58%)
Query: 147 VCGSDGHTYSSVCKLEQQACLSSKQLAVRCEGPC 180
VC SD TY+S C +++ AC S L V+ G C
Sbjct: 283 VCASDNATYASECAMKEAACSSGVLLEVKHSGSC 316
>gi|7242222 follistatin isoform FST344 precursor [Homo sapiens]
Length = 344
Score = 42.7 bits (99), Expect = 6e-04
Identities = 26/95 (27%), Positives = 38/95 (40%), Gaps = 21/95 (22%)
Query: 87 KDPCQKVKCSRHKVCIAQGYQRAMCISRKKLEHRIKQPTVKLHGNKDSIC-KPCHMAQLA 145
K C+ V C C+ A C++ + IC +P Q
Sbjct: 165 KKTCRDVFCPGSSTCVVDQTNNAYCVTCNR------------------ICPEPASSEQY- 205
Query: 146 SVCGSDGHTYSSVCKLEQQACLSSKQLAVRCEGPC 180
+CG+DG TYSS C L + CL + + + EG C
Sbjct: 206 -LCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKC 239
Score = 38.5 bits (88), Expect = 0.012
Identities = 27/120 (22%), Positives = 42/120 (35%), Gaps = 25/120 (20%)
Query: 63 DEVEDDYIKSWEDNQQGDEALDTTKDPCQKVKCSRHKVCIAQGYQRAMCISRKKLEHRIK 122
++V D+ + W G K+ C+ V C K C + C+
Sbjct: 68 EDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCGPGKKCRMNKKNKPRCV---------- 117
Query: 123 QPTVKLHGNKDSICKP--CHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQLAVRCEGPC 180
C P ++ VCG DG TY + C L + C +L V+ +G C
Sbjct: 118 -------------CAPDCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGRC 164
Score = 35.8 bits (81), Expect = 0.076
Identities = 17/47 (36%), Positives = 23/47 (48%)
Query: 147 VCGSDGHTYSSVCKLEQQACLSSKQLAVRCEGPCPCPTEQAATSTAD 193
VC SD TY+S C +++ AC S L V+ G C +E D
Sbjct: 283 VCASDNATYASECAMKEAACSSGVLLEVKHSGSCNSISEDTEEEEED 329
>gi|55925576 insulin-like growth factor binding protein 2, 36kDa
[Homo sapiens]
Length = 328
Score = 42.4 bits (98), Expect = 8e-04
Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 16/83 (19%)
Query: 310 KPPCLAELERIQIQEAAKKKP----------GIFIPSCDEDGYYRKMQCDQS----SGDC 355
+ PC EL+++ + + + P + IP+CD+ G Y QC S G+C
Sbjct: 227 RTPCQQELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGEC 286
Query: 356 WCVD-QLGLELTGTRT-HGSPDC 376
WCV+ G + G T G P+C
Sbjct: 287 WCVNPNTGKLIQGAPTIRGDPEC 309
>gi|166795236 tumor-associated calcium signal transducer 2 precursor
[Homo sapiens]
Length = 323
Score = 42.4 bits (98), Expect = 8e-04
Identities = 20/58 (34%), Positives = 34/58 (58%), Gaps = 2/58 (3%)
Query: 323 QEAAKKKPGIFIPSCDEDGYYRKMQCDQSSGDCWCVDQLGLELTGTRTHGSPDCDDIV 380
+ A G++ P CD +G ++ QC+Q+S CWCV+ +G+ T + S CD++V
Sbjct: 94 EHALVDNDGLYDPDCDPEGRFKARQCNQTS-VCWCVNSVGVRRT-DKGDLSLRCDELV 149
>gi|19923632 Kazal-type serine peptidase inhibitor domain 1
precursor [Homo sapiens]
Length = 304
Score = 41.6 bits (96), Expect = 0.001
Identities = 30/114 (26%), Positives = 50/114 (43%), Gaps = 22/114 (19%)
Query: 89 PCQKVKCSRHKVCIAQGYQRAM--CISRKKLEHRI--KQPTVKLHGN------------- 131
PC+ +C+ + C+A + A C LE ++ P+ +G+
Sbjct: 55 PCRPEECAAPRGCLAGRVRDACGCCWECANLEGQLCDLDPSAHFYGHCGEQLECRLDTGG 114
Query: 132 ---KDSICKP-CHMAQLASVCGSDGHTYSSVCKLEQQA-CLSSKQLAVRCEGPC 180
+ + +P C + +CGSDGHTYS +C+L++ A L V GPC
Sbjct: 115 DLSRGEVPEPLCACRSQSPLCGSDGHTYSQICRLQEAARARPDANLTVAHPGPC 168
>gi|29568105 transmembrane protein with EGF-like and two
follistatin-like domains 1 [Homo sapiens]
Length = 380
Score = 41.2 bits (95), Expect = 0.002
Identities = 30/124 (24%), Positives = 54/124 (43%), Gaps = 5/124 (4%)
Query: 131 NKDSICK-PCHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQLAVRCEGPCPCPTEQAAT 189
N +C C VC SDG +Y++ C + + +C+ +Q+ +R G C T+ T
Sbjct: 185 NVGCVCNIDCSGYSFNPVCASDGSSYNNPCFVREASCIKQEQIDIRHLGHC---TDTDDT 241
Query: 190 STADGKPETCTGQ-DLADLGDRLRDWFQLLHENSKQNGSASSVAGPASGLDKSLGASCKD 248
S K + + D+ D D+ D + H +N + + G + + ASC+
Sbjct: 242 SLLGKKDDGLQYRPDVKDASDQREDVYIGNHMPCPENLNGYCIHGKCEFIYSTQKASCRC 301
Query: 249 SIGW 252
G+
Sbjct: 302 ESGY 305
Score = 40.8 bits (94), Expect = 0.002
Identities = 18/42 (42%), Positives = 24/42 (57%), Gaps = 1/42 (2%)
Query: 139 CHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQLAVRCEGPC 180
CH + VCGS+G TY + C L + AC K++ V GPC
Sbjct: 103 CHTNYIP-VCGSNGDTYQNECFLRRAACKHQKEITVIARGPC 143
>gi|218505670 epithelial cell adhesion molecule precursor [Homo
sapiens]
Length = 314
Score = 40.8 bits (94), Expect = 0.002
Identities = 18/52 (34%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Query: 319 RIQIQEAAKKKPGIFIPSCDEDGYYRKMQCDQSSGDCWCVDQLGLELTGTRT 370
R + + A + G++ P CDE G ++ QC+ +S CWCV+ G+ T T
Sbjct: 81 RAKPEGALQNNDGLYDPDCDESGLFKAKQCNGTS-MCWCVNTAGVRRTDKDT 131
>gi|62243290 insulin-like growth factor binding protein 4 precursor
[Homo sapiens]
Length = 258
Score = 39.3 bits (90), Expect = 0.007
Identities = 27/79 (34%), Positives = 37/79 (46%), Gaps = 12/79 (15%)
Query: 313 CLAELERIQIQEAAKKKPG------IFIPSCDEDGYYRKMQC----DQSSGDCWCVD-QL 361
C +EL R + AA + I IP+CD +G + QC D G CWCVD +
Sbjct: 174 CQSELHRALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDRKT 233
Query: 362 GLELT-GTRTHGSPDCDDI 379
G++L G G DC +
Sbjct: 234 GVKLPGGLEPKGELDCHQL 252
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.424
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,035,563
Number of Sequences: 37866
Number of extensions: 938699
Number of successful extensions: 9513
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 218
Number of HSP's successfully gapped in prelim test: 70
Number of HSP's that attempted gapping in prelim test: 6364
Number of HSP's gapped (non-prelim): 2139
length of query: 424
length of database: 18,247,518
effective HSP length: 105
effective length of query: 319
effective length of database: 14,271,588
effective search space: 4552636572
effective search space used: 4552636572
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.