Search of human proteins with 7657419

Search of human proteins with 7657419

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7657419 opticin precursor [Homo sapiens]
         (332 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7657419 opticin precursor [Homo sapiens]                           661   0.0  
gi|68800360 dermatan sulfate proteoglycan 3 precursor [Homo sapi...   242   3e-64
gi|7661704 osteoglycin preproprotein [Homo sapiens]                   211   6e-55
gi|14916498 osteoglycin preproprotein [Homo sapiens]                  211   6e-55
gi|41349454 proline arginine-rich end leucine-rich repeat protei...    91   2e-18
gi|4506041 proline arginine-rich end leucine-rich repeat protein...    91   2e-18
gi|4826876 osteomodulin [Homo sapiens]                                 89   5e-18
gi|19743846 decorin isoform a preproprotein [Homo sapiens]             86   6e-17
gi|4503271 decorin isoform a preproprotein [Homo sapiens]              86   6e-17
gi|4505047 lumican precursor [Homo sapiens]                            86   6e-17
gi|109809759 leucine rich repeat transmembrane neuronal 3 [Homo ...    82   7e-16
gi|4502403 biglycan preproprotein [Homo sapiens]                       81   1e-15
gi|226342933 podocan-like 1 isoform 2 [Homo sapiens]                   79   4e-15
gi|226342931 podocan-like 1 isoform 1 [Homo sapiens]                   79   4e-15
gi|41350214 asporin [Homo sapiens]                                     79   6e-15
gi|5901992 keratocan [Homo sapiens]                                    78   1e-14
gi|126517478 peroxidasin homolog-like [Homo sapiens]                   78   1e-14
gi|156139147 leucine rich repeat transmembrane neuronal 4 isofor...    77   2e-14
gi|197927168 leucine rich repeat transmembrane neuronal 4 isofor...    77   2e-14
gi|226342935 podocan-like 1 isoform 3 [Homo sapiens]                   73   3e-13
gi|188528675 slit homolog 1 [Homo sapiens]                             73   3e-13
gi|86990456 leucine rich repeat transmembrane neuronal 1 [Homo s...    72   7e-13
gi|4557543 extracellular matrix protein 2 precursor [Homo sapiens]     72   7e-13
gi|45505137 podocan [Homo sapiens]                                     72   9e-13
gi|7662102 leucine rich repeat transmembrane neuronal 2 [Homo sa...    71   1e-12
gi|40217817 slit and trk like 1 protein [Homo sapiens]                 69   6e-12
gi|11321571 slit homolog 3 [Homo sapiens]                              69   6e-12
gi|40217823 SLIT and NTRK-like family, member 5 [Homo sapiens]         69   8e-12
gi|38202222 fibronectin leucine rich transmembrane protein 3 pre...    68   1e-11
gi|7019383 fibronectin leucine rich transmembrane protein 3 prec...    68   1e-11

>gi|7657419 opticin precursor [Homo sapiens]
          Length = 332

 Score =  661 bits (1706), Expect = 0.0
 Identities = 332/332 (100%), Positives = 332/332 (100%)

Query: 1   MRLLAFLSLLALVLQETGTASLPRKERKRREEQMPREGDSFEVLPLRNDVLNPDNYGEVI 60
           MRLLAFLSLLALVLQETGTASLPRKERKRREEQMPREGDSFEVLPLRNDVLNPDNYGEVI
Sbjct: 1   MRLLAFLSLLALVLQETGTASLPRKERKRREEQMPREGDSFEVLPLRNDVLNPDNYGEVI 60

Query: 61  DLSNYEELTDYGDQLPEVKVTSLAPATSISPAKSTTAPGTPSSNPTMTRPTTAGLLLSSQ 120
           DLSNYEELTDYGDQLPEVKVTSLAPATSISPAKSTTAPGTPSSNPTMTRPTTAGLLLSSQ
Sbjct: 61  DLSNYEELTDYGDQLPEVKVTSLAPATSISPAKSTTAPGTPSSNPTMTRPTTAGLLLSSQ 120

Query: 121 PNHGLPTCLVCVCLGSSVYCDDIDLEDIPPLPRRTAYLYARFNRISRIRAEDFKGLTKLK 180
           PNHGLPTCLVCVCLGSSVYCDDIDLEDIPPLPRRTAYLYARFNRISRIRAEDFKGLTKLK
Sbjct: 121 PNHGLPTCLVCVCLGSSVYCDDIDLEDIPPLPRRTAYLYARFNRISRIRAEDFKGLTKLK 180

Query: 181 RIDLSNNLISSIDNDAFRLLHALQDLILPENQLEALPVLPSGIEFLDVRLNRLQSSGIQP 240
           RIDLSNNLISSIDNDAFRLLHALQDLILPENQLEALPVLPSGIEFLDVRLNRLQSSGIQP
Sbjct: 181 RIDLSNNLISSIDNDAFRLLHALQDLILPENQLEALPVLPSGIEFLDVRLNRLQSSGIQP 240

Query: 241 AAFRAMEKLQFLYLSDNLLDSIPGPLPLSLRSVHLQNNLIETMQRDVFCDPEEHKHTRRQ 300
           AAFRAMEKLQFLYLSDNLLDSIPGPLPLSLRSVHLQNNLIETMQRDVFCDPEEHKHTRRQ
Sbjct: 241 AAFRAMEKLQFLYLSDNLLDSIPGPLPLSLRSVHLQNNLIETMQRDVFCDPEEHKHTRRQ 300

Query: 301 LEDIRLDGNPINLSLFPSAYFCLPRLPIGRFT 332
           LEDIRLDGNPINLSLFPSAYFCLPRLPIGRFT
Sbjct: 301 LEDIRLDGNPINLSLFPSAYFCLPRLPIGRFT 332


>gi|68800360 dermatan sulfate proteoglycan 3 precursor [Homo
           sapiens]
          Length = 322

 Score =  242 bits (618), Expect = 3e-64
 Identities = 117/214 (54%), Positives = 151/214 (70%)

Query: 116 LLSSQPNHGLPTCLVCVCLGSSVYCDDIDLEDIPPLPRRTAYLYARFNRISRIRAEDFKG 175
           +L    N   PTCL+C C+ ++VYCDD +L+ IPPLP+ TAY Y+RFNRI +I   DF  
Sbjct: 106 VLGPHTNEDFPTCLLCTCISTTVYCDDHELDAIPPLPKNTAYFYSRFNRIKKINKNDFAS 165

Query: 176 LTKLKRIDLSNNLISSIDNDAFRLLHALQDLILPENQLEALPVLPSGIEFLDVRLNRLQS 235
           L+ LKRIDL++NLIS ID DAFR L  L++L+L +N++  LP LP+ + F+D+  NRL  
Sbjct: 166 LSDLKRIDLTSNLISEIDEDAFRKLPQLRELVLRDNKIRQLPELPTTLTFIDISNNRLGR 225

Query: 236 SGIQPAAFRAMEKLQFLYLSDNLLDSIPGPLPLSLRSVHLQNNLIETMQRDVFCDPEEHK 295
            GI+  AF+ M  L  LYL+DN LD IP PLP +LR++HLQNN I  M  D FC+ +   
Sbjct: 226 KGIKQEAFKDMYDLHHLYLTDNNLDHIPLPLPENLRALHLQNNNILEMHEDTFCNVKNLT 285

Query: 296 HTRRQLEDIRLDGNPINLSLFPSAYFCLPRLPIG 329
           + R+ LEDIRLDGNPINLS  P AY CLPRLP+G
Sbjct: 286 YIRKALEDIRLDGNPINLSKTPQAYMCLPRLPVG 319


>gi|7661704 osteoglycin preproprotein [Homo sapiens]
          Length = 298

 Score =  211 bits (538), Expect = 6e-55
 Identities = 108/278 (38%), Positives = 162/278 (58%), Gaps = 16/278 (5%)

Query: 54  DNYGEVIDLSNYEELTDYGDQLPEVKVTSLAPATSISPAKSTTAPGTPSSNPTMTRPTTA 113
           DN+ E I   +YE+    G  + E +   +    S+   K       P            
Sbjct: 36  DNFEESIFSQDYEDKYLDGKNIKEKETVIIPNEKSLQLQKDEAITPLPPK---------- 85

Query: 114 GLLLSSQPNHGLPTCLVCVCLGSSVYCDDIDLEDIPPLPRRTAYLYARFNRISRIRAEDF 173
                 + N  +PTCL+CVCL  SVYC+++D++ +PPLP+ +AYLYARFN+I ++ A+DF
Sbjct: 86  ------KENDEMPTCLLCVCLSGSVYCEEVDIDAVPPLPKESAYLYARFNKIKKLTAKDF 139

Query: 174 KGLTKLKRIDLSNNLISSIDNDAFRLLHALQDLILPENQLEALPVLPSGIEFLDVRLNRL 233
             +  L+R+D + NLI  I++  F  L  L++L L ENQL  LPVLP  +   + + N++
Sbjct: 140 ADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQLLKLPVLPPKLTLFNAKYNKI 199

Query: 234 QSSGIQPAAFRAMEKLQFLYLSDNLLDSIPGPLPLSLRSVHLQNNLIETMQRDVFCDPEE 293
           +S GI+  AF+ +  L FLYL  N L+S+P  LP SLR +HLQ N I ++  D FC   +
Sbjct: 200 KSRGIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIHLQFNNIASITDDTFCKAND 259

Query: 294 HKHTRRQLEDIRLDGNPINLSLFPSAYFCLPRLPIGRF 331
             + R ++E+IRL+GNPI L   P+++ CL RLPIG +
Sbjct: 260 TSYIRDRIEEIRLEGNPIVLGKHPNSFICLKRLPIGSY 297


>gi|14916498 osteoglycin preproprotein [Homo sapiens]
          Length = 298

 Score =  211 bits (538), Expect = 6e-55
 Identities = 108/278 (38%), Positives = 162/278 (58%), Gaps = 16/278 (5%)

Query: 54  DNYGEVIDLSNYEELTDYGDQLPEVKVTSLAPATSISPAKSTTAPGTPSSNPTMTRPTTA 113
           DN+ E I   +YE+    G  + E +   +    S+   K       P            
Sbjct: 36  DNFEESIFSQDYEDKYLDGKNIKEKETVIIPNEKSLQLQKDEAITPLPPK---------- 85

Query: 114 GLLLSSQPNHGLPTCLVCVCLGSSVYCDDIDLEDIPPLPRRTAYLYARFNRISRIRAEDF 173
                 + N  +PTCL+CVCL  SVYC+++D++ +PPLP+ +AYLYARFN+I ++ A+DF
Sbjct: 86  ------KENDEMPTCLLCVCLSGSVYCEEVDIDAVPPLPKESAYLYARFNKIKKLTAKDF 139

Query: 174 KGLTKLKRIDLSNNLISSIDNDAFRLLHALQDLILPENQLEALPVLPSGIEFLDVRLNRL 233
             +  L+R+D + NLI  I++  F  L  L++L L ENQL  LPVLP  +   + + N++
Sbjct: 140 ADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQLLKLPVLPPKLTLFNAKYNKI 199

Query: 234 QSSGIQPAAFRAMEKLQFLYLSDNLLDSIPGPLPLSLRSVHLQNNLIETMQRDVFCDPEE 293
           +S GI+  AF+ +  L FLYL  N L+S+P  LP SLR +HLQ N I ++  D FC   +
Sbjct: 200 KSRGIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIHLQFNNIASITDDTFCKAND 259

Query: 294 HKHTRRQLEDIRLDGNPINLSLFPSAYFCLPRLPIGRF 331
             + R ++E+IRL+GNPI L   P+++ CL RLPIG +
Sbjct: 260 TSYIRDRIEEIRLEGNPIVLGKHPNSFICLKRLPIGSY 297


>gi|41349454 proline arginine-rich end leucine-rich repeat protein
           precursor [Homo sapiens]
          Length = 382

 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 73/254 (28%), Positives = 108/254 (42%), Gaps = 40/254 (15%)

Query: 75  LPEVKVTSLAPATSISPAKSTTAPGT---PSSNPTMT--------RPTTAGLLLSSQPNH 123
           LP + + S+A        +  T PG    P   PT +         PT     L   P  
Sbjct: 9   LPLLILASVAQGQPTRRPRPGTGPGRRPRPRPRPTPSFPQPDEPAEPTDLPPPLPPGPPS 68

Query: 124 GLPTC-LVCVC---LGSSVYCDDIDLEDIPPLPRRTAYLYARFNRISRIRAEDFKGLTKL 179
             P C   C C     S++YCD  +L  +P +P R  YLY + N I+ +  E F+  T L
Sbjct: 69  IFPDCPRECYCPPDFPSALYCDSRNLRKVPVIPPRIHYLYLQNNFITELPVESFQNATGL 128

Query: 180 KRIDLSNNLISSIDNDAFRLLHALQDLILPENQLEALP-VLPSGIE-------------- 224
           + I+L NN I  ID      L  L  L + +NQLE +P  LP  +E              
Sbjct: 129 RWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIPP 188

Query: 225 ----------FLDVRLNRLQSSGIQPAAFRAMEKLQFLYLSDNLLDSIPGPLPLSLRSVH 274
                      LD++ NRL     +P  F  ++ L  L L+ N+L  +P  +P ++  ++
Sbjct: 189 GVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTAIHQLY 248

Query: 275 LQNNLIETMQRDVF 288
           L +N IET+    F
Sbjct: 249 LDSNKIETIPNGYF 262



 Score = 29.3 bits (64), Expect = 5.1
 Identities = 35/142 (24%), Positives = 62/142 (43%), Gaps = 20/142 (14%)

Query: 145 LEDIPP-LPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLIS--SIDNDAFRLLH 201
           L  +PP +P     LY   N+I  I    FK    L  I L+ N ++   +  ++F + +
Sbjct: 233 LRKMPPRVPTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSFNISN 292

Query: 202 ALQDLILPENQLEALPVLPSGIEFLDVRLNRLQS-SGIQ------------PAAFRAMEK 248
            L  L L  N++ ++P + + +E L +  N ++  +G Q             +    +  
Sbjct: 293 LLV-LHLSHNRISSVPAINNRLEHLYLNNNSIEKINGTQICPNDLVAFHDFSSDLENVPH 351

Query: 249 LQFLYLSDNLLDSIPGPLPLSL 270
           L++L L  N L     P+PL L
Sbjct: 352 LRYLRLDGNYLKP---PIPLDL 370


>gi|4506041 proline arginine-rich end leucine-rich repeat protein
           precursor [Homo sapiens]
          Length = 382

 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 73/254 (28%), Positives = 108/254 (42%), Gaps = 40/254 (15%)

Query: 75  LPEVKVTSLAPATSISPAKSTTAPGT---PSSNPTMT--------RPTTAGLLLSSQPNH 123
           LP + + S+A        +  T PG    P   PT +         PT     L   P  
Sbjct: 9   LPLLILASVAQGQPTRRPRPGTGPGRRPRPRPRPTPSFPQPDEPAEPTDLPPPLPPGPPS 68

Query: 124 GLPTC-LVCVC---LGSSVYCDDIDLEDIPPLPRRTAYLYARFNRISRIRAEDFKGLTKL 179
             P C   C C     S++YCD  +L  +P +P R  YLY + N I+ +  E F+  T L
Sbjct: 69  IFPDCPRECYCPPDFPSALYCDSRNLRKVPVIPPRIHYLYLQNNFITELPVESFQNATGL 128

Query: 180 KRIDLSNNLISSIDNDAFRLLHALQDLILPENQLEALP-VLPSGIE-------------- 224
           + I+L NN I  ID      L  L  L + +NQLE +P  LP  +E              
Sbjct: 129 RWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIPP 188

Query: 225 ----------FLDVRLNRLQSSGIQPAAFRAMEKLQFLYLSDNLLDSIPGPLPLSLRSVH 274
                      LD++ NRL     +P  F  ++ L  L L+ N+L  +P  +P ++  ++
Sbjct: 189 GVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTAIHQLY 248

Query: 275 LQNNLIETMQRDVF 288
           L +N IET+    F
Sbjct: 249 LDSNKIETIPNGYF 262



 Score = 29.3 bits (64), Expect = 5.1
 Identities = 35/142 (24%), Positives = 62/142 (43%), Gaps = 20/142 (14%)

Query: 145 LEDIPP-LPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLIS--SIDNDAFRLLH 201
           L  +PP +P     LY   N+I  I    FK    L  I L+ N ++   +  ++F + +
Sbjct: 233 LRKMPPRVPTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSFNISN 292

Query: 202 ALQDLILPENQLEALPVLPSGIEFLDVRLNRLQS-SGIQ------------PAAFRAMEK 248
            L  L L  N++ ++P + + +E L +  N ++  +G Q             +    +  
Sbjct: 293 LLV-LHLSHNRISSVPAINNRLEHLYLNNNSIEKINGTQICPNDLVAFHDFSSDLENVPH 351

Query: 249 LQFLYLSDNLLDSIPGPLPLSL 270
           L++L L  N L     P+PL L
Sbjct: 352 LRYLRLDGNYLKP---PIPLDL 370


>gi|4826876 osteomodulin [Homo sapiens]
          Length = 421

 Score = 89.0 bits (219), Expect = 5e-18
 Identities = 74/218 (33%), Positives = 96/218 (44%), Gaps = 32/218 (14%)

Query: 131 CVC---LGSSVYCDDIDLEDIPPLPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNN 187
           C C     SS+YCD+  L+ IP +P     LY +FN I  + A  F   T LK I+LS+N
Sbjct: 66  CFCPTNFPSSMYCDNRKLKTIPNIPMHIQQLYLQFNEIEAVTANSFINATHLKEINLSHN 125

Query: 188 LISS--IDNDAFRLLHALQDLILPENQLEALPV-LPSGIE-------------------- 224
            I S  ID   F  L  L  L L  N LE  P  LP  +E                    
Sbjct: 126 KIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTNAMDGL 185

Query: 225 ----FLDVRLNRLQSSGIQPAAFRAMEKLQFLYLSDNLLDSIPGPLPLSLRSVHLQNNLI 280
                LD+  N L  S ++   F  MEKL  L L  N L+S+P  LP SL  + L+NN I
Sbjct: 186 VNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSLENNSI 245

Query: 281 ETMQRDVFCDPEEHKHTRRQLEDIRLDGNPINLSLFPS 318
            ++    F D     HT R   + +L   P N+   P+
Sbjct: 246 SSIPEKYF-DKLPKLHTLRMSHN-KLQDIPYNIFNLPN 281



 Score = 74.3 bits (181), Expect = 1e-13
 Identities = 63/212 (29%), Positives = 94/212 (44%), Gaps = 35/212 (16%)

Query: 144 DLEDIP-PLPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLI--SSIDNDAFRLL 200
           +LE+ P PLP+    L   +N IS+++     GL  L  +DL  N +  S + +  F  +
Sbjct: 152 NLEEFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKM 211

Query: 201 HALQDLILPENQLEALPV-LPSGIEFLDVRLNRLQSSGIQPAAFRAMEKLQFLYLSDNLL 259
             L  L L  N+LE++P  LPS + +L +  N + S  I    F  + KL  L +S N L
Sbjct: 212 EKLMQLNLCSNRLESMPPGLPSSLMYLSLENNSISS--IPEKYFDKLPKLHTLRMSHNKL 269

Query: 260 DSIPGPL----------------------PLSLRSVHLQNNLIETMQRDVFC---DPEEH 294
             IP  +                      P +L  ++LQNN IE M   V C   DP  +
Sbjct: 270 QDIPYNIFNLPNIVELSVGHNKLKQAFYIPRNLEHLYLQNNEIEKMNLTVMCPSIDPLHY 329

Query: 295 KHTRRQLEDIRLDGNPINLSLFPSAYFCLPRL 326
            H    L  IR+D N +   +    +FC P +
Sbjct: 330 HH----LTYIRVDQNKLKEPISSYIFFCFPHI 357


>gi|19743846 decorin isoform a preproprotein [Homo sapiens]
          Length = 359

 Score = 85.5 bits (210), Expect = 6e-17
 Identities = 64/188 (34%), Positives = 93/188 (49%), Gaps = 28/188 (14%)

Query: 120 QPNHGLPTC-LVCVCLGSSVYCDDIDLEDIPP-LPRRTAYLYARFNRISRIRAEDFKGLT 177
           +P+ G P C   C C    V C D+ L+ +P  LP  T  L  + N+I+ I+  DFK L 
Sbjct: 47  EPSLG-PVCPFRCQCHLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLK 105

Query: 178 KLKRIDLSNNLISSIDNDAFRLLHALQDLILPENQLEALPV-LPSGIEFL---------- 226
            L  + L NN IS +   AF  L  L+ L L +NQL+ LP  +P  ++ L          
Sbjct: 106 NLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKV 165

Query: 227 --------------DVRLNRLQSSGIQPAAFRAMEKLQFLYLSDNLLDSIPGPLPLSLRS 272
                         ++  N L+SSGI+  AF+ M+KL ++ ++D  + SIP  LP SL  
Sbjct: 166 RKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTE 225

Query: 273 VHLQNNLI 280
           +HL  N I
Sbjct: 226 LHLDGNKI 233



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 28/77 (36%), Positives = 42/77 (54%), Gaps = 1/77 (1%)

Query: 142 DIDLEDIPP-LPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLISSIDNDAFRLL 200
           D ++  IP  LP     L+   N+ISR+ A   KGL  L ++ LS N IS++DN +    
Sbjct: 209 DTNITSIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANT 268

Query: 201 HALQDLILPENQLEALP 217
             L++L L  N+L  +P
Sbjct: 269 PHLRELHLDNNKLTRVP 285


>gi|4503271 decorin isoform a preproprotein [Homo sapiens]
          Length = 359

 Score = 85.5 bits (210), Expect = 6e-17
 Identities = 64/188 (34%), Positives = 93/188 (49%), Gaps = 28/188 (14%)

Query: 120 QPNHGLPTC-LVCVCLGSSVYCDDIDLEDIPP-LPRRTAYLYARFNRISRIRAEDFKGLT 177
           +P+ G P C   C C    V C D+ L+ +P  LP  T  L  + N+I+ I+  DFK L 
Sbjct: 47  EPSLG-PVCPFRCQCHLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLK 105

Query: 178 KLKRIDLSNNLISSIDNDAFRLLHALQDLILPENQLEALPV-LPSGIEFL---------- 226
            L  + L NN IS +   AF  L  L+ L L +NQL+ LP  +P  ++ L          
Sbjct: 106 NLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKV 165

Query: 227 --------------DVRLNRLQSSGIQPAAFRAMEKLQFLYLSDNLLDSIPGPLPLSLRS 272
                         ++  N L+SSGI+  AF+ M+KL ++ ++D  + SIP  LP SL  
Sbjct: 166 RKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTE 225

Query: 273 VHLQNNLI 280
           +HL  N I
Sbjct: 226 LHLDGNKI 233



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 28/77 (36%), Positives = 42/77 (54%), Gaps = 1/77 (1%)

Query: 142 DIDLEDIPP-LPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLISSIDNDAFRLL 200
           D ++  IP  LP     L+   N+ISR+ A   KGL  L ++ LS N IS++DN +    
Sbjct: 209 DTNITSIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANT 268

Query: 201 HALQDLILPENQLEALP 217
             L++L L  N+L  +P
Sbjct: 269 PHLRELHLDNNKLTRVP 285


>gi|4505047 lumican precursor [Homo sapiens]
          Length = 338

 Score = 85.5 bits (210), Expect = 6e-17
 Identities = 66/224 (29%), Positives = 109/224 (48%), Gaps = 30/224 (13%)

Query: 119 SQPNHGLPTCLVCVCLGSSVYCDDIDLEDIPPLPRRTAYLYARFNRISRIRAEDFKGLTK 178
           S PN   P C       S++YCD++ L+ +P +P    YLY R N+I  I  + F+ +T 
Sbjct: 33  SSPNCA-PECNCPESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQIDHIDEKAFENVTD 91

Query: 179 LKRIDLSNNLI--SSIDNDAFRLLHALQDLILPENQL-EALPVLPSGIE----------- 224
           L+ + L +NL+  S I    F  L  L+ L +  N L E++  LP  +E           
Sbjct: 92  LQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITK 151

Query: 225 -----------FLDVRLNRLQSSGIQPAAFRAMEKLQFLYLSDNLLDSIPGPLPLSLRSV 273
                      F+ ++ NRL+   +  AAF+ ++ L++L LS N +  +P  LP+SL ++
Sbjct: 152 LGSFEGLVNLTFIHLQHNRLKEDAVS-AAFKGLKSLEYLDLSFNQIARLPSGLPVSLLTL 210

Query: 274 HLQNNLIETMQRDVFCDPEEHKHTR---RQLEDIRLDGNPINLS 314
           +L NN I  +  + F      ++ R    +L D  + GN  N+S
Sbjct: 211 YLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVS 254



 Score = 36.6 bits (83), Expect = 0.032
 Identities = 28/91 (30%), Positives = 48/91 (52%), Gaps = 3/91 (3%)

Query: 151 LPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLI--SSIDNDAFRLLHALQDLIL 208
           LP     LY   N+IS I  E FK    L+ + LS+N +  S I  ++F +  +L +L L
Sbjct: 203 LPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNV-SSLVELDL 261

Query: 209 PENQLEALPVLPSGIEFLDVRLNRLQSSGIQ 239
             N+L+ +P +   +E   + +N+L+   I+
Sbjct: 262 SYNKLKNIPTVNENLENYYLEVNQLEKFDIK 292


>gi|109809759 leucine rich repeat transmembrane neuronal 3 [Homo
           sapiens]
          Length = 581

 Score = 82.0 bits (201), Expect = 7e-16
 Identities = 68/219 (31%), Positives = 110/219 (50%), Gaps = 26/219 (11%)

Query: 112 TAGLLLSSQPNHGLPTCLVCVCLGSSVYCDDIDLEDIPP-LPRRTAYLYARFNRISRIRA 170
           T  L + S    G P    C C G  VYC+   L++IP  +      L  R+N + +++ 
Sbjct: 21  TVLLTMLSSAERGCPKG--CRCEGKMVYCESQKLQEIPSSISAGCLGLSLRYNSLQKLKY 78

Query: 171 EDFKGLTKLKRIDLSNNLISSIDNDAFRLLHALQDLILPENQLEAL------PVLPSGIE 224
             FKGL +L  + L +N IS+ID +AF  +  L++LIL  N++         PV  + + 
Sbjct: 79  NQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPV--TNLR 136

Query: 225 FLDVRLNRLQSSGIQPAAFRAMEKLQFLYLSDNLLDSIPGPLPLSLRSVHLQN---NLIE 281
            LD+  N+L S G +   FR + KL  L+L  N L +IP  +    R++ L +   N I 
Sbjct: 137 NLDLSYNQLHSLGSE--QFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIR 194

Query: 282 TMQRDVFCDPEEHKHTRRQLEDIRLDGN---PINLSLFP 317
           ++ R+VF           +L+++ L+ N    +NL+LFP
Sbjct: 195 SLARNVFAG-------MIRLKELHLEHNQFSKLNLALFP 226



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 37/128 (28%), Positives = 64/128 (50%), Gaps = 10/128 (7%)

Query: 162 FNRISRIRAEDFKGLTKLKRIDLSNNLISSIDNDAFRLLHALQDLILPENQL----EALP 217
           +NRI  +    F G+ +LK + L +N  S ++   F  L +LQ+L L  N++    + + 
Sbjct: 190 YNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMS 249

Query: 218 VLPSGIEFLDVRLNRLQS-SGIQPAAFRAMEKLQFLYLSDNLLDSIPGPLP---LSLRSV 273
              S ++ LD+  N +++ SG  P+ F+ +  LQ L L  N L  I   +    +SL  +
Sbjct: 250 WTWSSLQRLDLSGNEIEAFSG--PSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLNDI 307

Query: 274 HLQNNLIE 281
            L  N+ E
Sbjct: 308 SLAGNIWE 315


>gi|4502403 biglycan preproprotein [Homo sapiens]
          Length = 368

 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 61/180 (33%), Positives = 86/180 (47%), Gaps = 27/180 (15%)

Query: 131 CVCLGSSVYCDDIDLEDIPP-LPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLI 189
           C C    V C D+ L+ +P  +   T  L  + N IS +R +DFKGL  L  + L NN I
Sbjct: 67  CHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKI 126

Query: 190 SSIDNDAFRLLHALQDLILPENQL-EALPVLPSGIEFLDVRLNR---------------- 232
           S I   AF  L  LQ L + +N L E  P LPS +  L +  NR                
Sbjct: 127 SKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMN 186

Query: 233 --------LQSSGIQPAAFRAMEKLQFLYLSDNLLDSIPGPLPLSLRSVHLQNNLIETMQ 284
                   L++SG +P AF  + KL +L +S+  L  IP  LP +L  +HL +N I+ ++
Sbjct: 187 CIEMGGNPLENSGFEPGAFDGL-KLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIE 245



 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 44/140 (31%), Positives = 61/140 (43%), Gaps = 30/140 (21%)

Query: 182 IDLSNNLISSIDNDAFRLLHALQDLILPENQLEALPVLPSGIEFLDVRLNRLQSSGIQPA 241
           +DL NN IS +  D F+ L  L  L+L  N++                      S I   
Sbjct: 95  LDLQNNDISELRKDDFKGLQHLYALVLVNNKI----------------------SKIHEK 132

Query: 242 AFRAMEKLQFLYLSDNLLDSIPGPLPLSLRSVHLQNNLIETMQRDVFCDPEEHKHTRRQL 301
           AF  + KLQ LY+S N L  IP  LP SL  + + +N I  + + VF          R +
Sbjct: 133 AFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSG-------LRNM 185

Query: 302 EDIRLDGNPINLSLF-PSAY 320
             I + GNP+  S F P A+
Sbjct: 186 NCIEMGGNPLENSGFEPGAF 205



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 23/67 (34%), Positives = 34/67 (50%)

Query: 151 LPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLISSIDNDAFRLLHALQDLILPE 210
           LP     L+   N+I  I  ED    +KL R+ L +N I  I+N +   L  L++L L  
Sbjct: 227 LPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDN 286

Query: 211 NQLEALP 217
           N+L  +P
Sbjct: 287 NKLARVP 293


>gi|226342933 podocan-like 1 isoform 2 [Homo sapiens]
          Length = 510

 Score = 79.3 bits (194), Expect = 4e-15
 Identities = 67/212 (31%), Positives = 99/212 (46%), Gaps = 36/212 (16%)

Query: 110 PTTAGLLLSSQPNHG-----LPTC--LVCVCLG-SSVYCDDIDLEDIPP-LPRRTAYLYA 160
           P  AGL  ++ P+ G     LP    L C C    +V CD +DL   P  + R   +L  
Sbjct: 20  PPVAGLEDAAFPHLGESLQPLPRACPLRCSCPRVDTVDCDGLDLRVFPDNITRAAQHLSL 79

Query: 161 RFNRISRIRAEDFKGLTKLKRIDLSNNLISS--IDNDAFRLLHALQDLILPENQLEALP- 217
           + N++  +   +   L+ L+ ++L NNLISS  + ++AF  L  LQ L +  N+L   P 
Sbjct: 80  QNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAHNKLSVAPQ 139

Query: 218 VLPSGIEFLDVRLNR------------------------LQSSGIQPAAFRAMEKLQFLY 253
            LP  +   D+  N+                        L ++G+ P AFR  E +  L 
Sbjct: 140 FLPRSLRVADLAANQVMEIFPLTFGEKPALRSVYLHNNQLSNAGLPPDAFRGSEAIATLS 199

Query: 254 LSDNLLDSIPGPLPLSLRSVHLQNNLIETMQR 285
           LS+N L  +P  LP SL  +HLQNNLI  + R
Sbjct: 200 LSNNQLSYLPPSLPPSLERLHLQNNLISKVPR 231



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 52/186 (27%), Positives = 82/186 (44%), Gaps = 32/186 (17%)

Query: 151 LPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLISSIDNDA-----FRLLHAL-- 203
           LPR  A L+   NRI ++ A    G   L+ + L +N + S    A      R LH L  
Sbjct: 283 LPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHL 342

Query: 204 ----------------QDLILPENQLEALP----VLPSGIEFLDVRLNRLQSSGIQPAAF 243
                           + L+LP N + AL     V   G+  L++  NRL S+ +   AF
Sbjct: 343 YGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAF 402

Query: 244 RAMEKLQFLYLSDNLLDSIPGPLPLSLRSVHLQNNLIETMQRDVFCDPEEHK-----HTR 298
           R +  L+ L L+ N L  +P  LP  LR++ LQ N +  ++ +     ++ +     H R
Sbjct: 403 RRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNR 462

Query: 299 RQLEDI 304
            ++ DI
Sbjct: 463 LRVGDI 468



 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 53/195 (27%), Positives = 78/195 (40%), Gaps = 34/195 (17%)

Query: 151 LPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLISS--IDNDAFRLLHALQDLIL 208
           LPR         N++  I    F     L+ + L NN +S+  +  DAFR   A+  L L
Sbjct: 141 LPRSLRVADLAANQVMEIFPLTFGEKPALRSVYLHNNQLSNAGLPPDAFRGSEAIATLSL 200

Query: 209 PENQLEALPV-LPSGIEFLDVRLN------------------------RLQSSGIQPAAF 243
             NQL  LP  LP  +E L ++ N                        +L  SG+    F
Sbjct: 201 SNNQLSYLPPSLPPSLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTF 260

Query: 244 RAMEKLQFLYLSDNLLDSIPGPLPLSLRSVHLQNNLIETMQRDVFCDPEEHKHTRRQLED 303
             +  L++L LS N L ++P  LP +L  +HL  N I  ++           H  R L  
Sbjct: 261 SKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVE-------AARLHGARGLRY 313

Query: 304 IRLDGNPINLSLFPS 318
           + L  N +  S  P+
Sbjct: 314 LLLQHNQLGSSGLPA 328


>gi|226342931 podocan-like 1 isoform 1 [Homo sapiens]
          Length = 512

 Score = 79.3 bits (194), Expect = 4e-15
 Identities = 67/212 (31%), Positives = 99/212 (46%), Gaps = 36/212 (16%)

Query: 110 PTTAGLLLSSQPNHG-----LPTC--LVCVCLG-SSVYCDDIDLEDIPP-LPRRTAYLYA 160
           P  AGL  ++ P+ G     LP    L C C    +V CD +DL   P  + R   +L  
Sbjct: 22  PPVAGLEDAAFPHLGESLQPLPRACPLRCSCPRVDTVDCDGLDLRVFPDNITRAAQHLSL 81

Query: 161 RFNRISRIRAEDFKGLTKLKRIDLSNNLISS--IDNDAFRLLHALQDLILPENQLEALP- 217
           + N++  +   +   L+ L+ ++L NNLISS  + ++AF  L  LQ L +  N+L   P 
Sbjct: 82  QNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAHNKLSVAPQ 141

Query: 218 VLPSGIEFLDVRLNR------------------------LQSSGIQPAAFRAMEKLQFLY 253
            LP  +   D+  N+                        L ++G+ P AFR  E +  L 
Sbjct: 142 FLPRSLRVADLAANQVMEIFPLTFGEKPALRSVYLHNNQLSNAGLPPDAFRGSEAIATLS 201

Query: 254 LSDNLLDSIPGPLPLSLRSVHLQNNLIETMQR 285
           LS+N L  +P  LP SL  +HLQNNLI  + R
Sbjct: 202 LSNNQLSYLPPSLPPSLERLHLQNNLISKVPR 233



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 52/186 (27%), Positives = 82/186 (44%), Gaps = 32/186 (17%)

Query: 151 LPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLISSIDNDA-----FRLLHAL-- 203
           LPR  A L+   NRI ++ A    G   L+ + L +N + S    A      R LH L  
Sbjct: 285 LPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHL 344

Query: 204 ----------------QDLILPENQLEALP----VLPSGIEFLDVRLNRLQSSGIQPAAF 243
                           + L+LP N + AL     V   G+  L++  NRL S+ +   AF
Sbjct: 345 YGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAF 404

Query: 244 RAMEKLQFLYLSDNLLDSIPGPLPLSLRSVHLQNNLIETMQRDVFCDPEEHK-----HTR 298
           R +  L+ L L+ N L  +P  LP  LR++ LQ N +  ++ +     ++ +     H R
Sbjct: 405 RRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNR 464

Query: 299 RQLEDI 304
            ++ DI
Sbjct: 465 LRVGDI 470



 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 53/195 (27%), Positives = 78/195 (40%), Gaps = 34/195 (17%)

Query: 151 LPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLISS--IDNDAFRLLHALQDLIL 208
           LPR         N++  I    F     L+ + L NN +S+  +  DAFR   A+  L L
Sbjct: 143 LPRSLRVADLAANQVMEIFPLTFGEKPALRSVYLHNNQLSNAGLPPDAFRGSEAIATLSL 202

Query: 209 PENQLEALPV-LPSGIEFLDVRLN------------------------RLQSSGIQPAAF 243
             NQL  LP  LP  +E L ++ N                        +L  SG+    F
Sbjct: 203 SNNQLSYLPPSLPPSLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTF 262

Query: 244 RAMEKLQFLYLSDNLLDSIPGPLPLSLRSVHLQNNLIETMQRDVFCDPEEHKHTRRQLED 303
             +  L++L LS N L ++P  LP +L  +HL  N I  ++           H  R L  
Sbjct: 263 SKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVE-------AARLHGARGLRY 315

Query: 304 IRLDGNPINLSLFPS 318
           + L  N +  S  P+
Sbjct: 316 LLLQHNQLGSSGLPA 330


>gi|41350214 asporin [Homo sapiens]
          Length = 380

 Score = 79.0 bits (193), Expect = 6e-15
 Identities = 55/184 (29%), Positives = 87/184 (47%), Gaps = 27/184 (14%)

Query: 131 CVCLGSSVYCDDIDLEDIPP-LPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLI 189
           C C    V+C D+ L  +P  +P  T  L  + N+I  I+  DFKGLT L  + L+NN +
Sbjct: 79  CQCYSRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKL 138

Query: 190 SSIDNDAFRLLHALQDLILPENQLEALPV-LP------------------------SGIE 224
           + I   AF     L+ L L  NQL  +P+ LP                        + + 
Sbjct: 139 TKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLPKSLAELRIHENKVKKIQKDTFKGMNALH 198

Query: 225 FLDVRLNRLQSSGIQPAAFRAMEKLQFLYLSDNLLDSIPGPLPLSLRSVHLQNNLIETMQ 284
            L++  N L ++GI+P AF  +     + +++  L S+P  LP +L  +HL  N I T++
Sbjct: 199 VLEMSANPLDNNGIEPGAFEGVTVFH-IRIAEAKLTSVPKGLPPTLLELHLDYNKISTVE 257

Query: 285 RDVF 288
            + F
Sbjct: 258 LEDF 261



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 23/78 (29%), Positives = 45/78 (57%)

Query: 151 LPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLISSIDNDAFRLLHALQDLILPE 210
           LP     L+  +N+IS +  EDFK   +L+R+ L NN I+ I+N +   +  ++++ L  
Sbjct: 239 LPPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIHLEN 298

Query: 211 NQLEALPVLPSGIEFLDV 228
           N+L+ +P     +++L +
Sbjct: 299 NKLKKIPSGLPELKYLQI 316


>gi|5901992 keratocan [Homo sapiens]
          Length = 352

 Score = 77.8 bits (190), Expect = 1e-14
 Identities = 63/229 (27%), Positives = 107/229 (46%), Gaps = 37/229 (16%)

Query: 123 HGLPTCLVCVCLGS---SVYCDDIDLEDIPPLPRRTAYLYARFNRISRIRAEDFKGLTKL 179
           H     + C C  S   ++YC++  L++IP +P R  YLY + N I  I  + F+  T+L
Sbjct: 38  HDFECPMECFCPPSFPTALYCENRGLKEIPAIPSRIWYLYLQNNLIETIPEKPFENATQL 97

Query: 180 KRIDLSNNLISS--IDNDAFRLLHALQDLILPENQLEALP-VLPSGIE------------ 224
           + I+L+ N I++  I+  A   L  L  L L +N+LE +P  LP  +E            
Sbjct: 98  RWINLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRI 157

Query: 225 ------------FLDVRLNRLQSSGIQPAAFRAMEKLQFLYLSDNLLDSIPGPLPLSLRS 272
                        LD++ N+L  +  Q   F+ ++ L  L ++ N L ++P  LP +   
Sbjct: 158 PQGTFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQ 217

Query: 273 VHLQNNLIETMQRDVFCDPEEHKHTRRQLEDIRLDGNPINLSLFPSAYF 321
           + L NN IE +       PE + +   ++  +RL+ N ++    PS  F
Sbjct: 218 LFLDNNSIEGI-------PENYFNVIPKVAFLRLNHNKLSDEGLPSRGF 259


>gi|126517478 peroxidasin homolog-like [Homo sapiens]
          Length = 1463

 Score = 77.8 bits (190), Expect = 1e-14
 Identities = 52/144 (36%), Positives = 75/144 (52%), Gaps = 6/144 (4%)

Query: 124 GLPTCLVCVCLGSSVYCDDIDLEDIPPLPRRTAYLYARFNRISRIRAEDFKGLTKLKRID 183
           GLP    C+C  S+V C  + L+ IP +P++T  L  RFNRI  I    FK L  L  + 
Sbjct: 21  GLPCPSRCLCFKSTVRCMHLMLDHIPQVPQQTTVLDLRFNRIREIPGSAFKKLKNLNTLL 80

Query: 184 LSNNLISSIDNDAFRLLHALQDLILPENQLEALPVLP----SGIEFLDVRLNRLQSSGIQ 239
           L+NN I  I  +AF  L  L  L L +N++ AL          +E L +  N+L+   +Q
Sbjct: 81  LNNNHIRKISRNAFEGLENLLYLYLYKNEIHALDKQTFKGLISLEHLYIHFNQLEM--LQ 138

Query: 240 PAAFRAMEKLQFLYLSDNLLDSIP 263
           P  F  + +L+ L+L +N L  IP
Sbjct: 139 PETFGDLLRLERLFLHNNKLSKIP 162



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 21/57 (36%), Positives = 33/57 (57%)

Query: 157 YLYARFNRISRIRAEDFKGLTKLKRIDLSNNLISSIDNDAFRLLHALQDLILPENQL 213
           +LY  FN++  ++ E F  L +L+R+ L NN +S I   +F  L +L+ L L  N L
Sbjct: 126 HLYIHFNQLEMLQPETFGDLLRLERLFLHNNKLSKIPAGSFSNLDSLKRLRLDSNAL 182


>gi|156139147 leucine rich repeat transmembrane neuronal 4 isoform b
           [Homo sapiens]
          Length = 518

 Score = 77.0 bits (188), Expect = 2e-14
 Identities = 61/203 (30%), Positives = 102/203 (50%), Gaps = 24/203 (11%)

Query: 131 CVCLGSSVYCDDIDLEDIPP-LPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLI 189
           C C G  VYC+     DIP  +   +  L  RFN I ++++  F GL +L  + L +N I
Sbjct: 38  CRCDGKIVYCESHAFADIPENISGGSQGLSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYI 97

Query: 190 SSIDNDAFRLLHALQDLILPENQLEAL------PVLPSGIEFLDVRLNRLQSSGIQPAAF 243
           SS+D DAF+ +  L++LIL  N++  L      PV    +  LD+  N+LQ+  +Q   F
Sbjct: 98  SSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPV--PNLRNLDLSYNKLQT--LQSEQF 153

Query: 244 RAMEKLQFLYLSDNLLDSIPGPLPLSLRS---VHLQNNLIETMQRDVFCDPEEHKHTRRQ 300
           + + KL  L+L  N L ++P  +    R+   + L  N + ++ R+ F           +
Sbjct: 154 KGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAG-------LLK 206

Query: 301 LEDIRLDGN---PINLSLFPSAY 320
           L+++ L+ N    IN + FP  +
Sbjct: 207 LKELHLEHNQFSKINFAHFPRLF 229



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 42/136 (30%), Positives = 64/136 (47%), Gaps = 9/136 (6%)

Query: 153 RRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLISSIDNDAFRLLHALQDLILPENQ 212
           R   +L   +NR+  +    F GL KLK + L +N  S I+   F  L  L+ + L  N+
Sbjct: 181 RNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNR 240

Query: 213 L----EALPVLPSGIEFLDVRLNRLQSSGIQPAAFRAMEKLQFLYLSDNLLDSIPGPLP- 267
           +    + L    S +  LD+  N +Q  GI+P  F+ +  LQ L L  N L +I      
Sbjct: 241 IRSISQGLTWTWSSLHNLDLSGNDIQ--GIEPGTFKCLPNLQKLNLDSNKLTNISQETVN 298

Query: 268 --LSLRSVHLQNNLIE 281
             +SL S+ L  N+ E
Sbjct: 299 AWISLISITLSGNMWE 314


>gi|197927168 leucine rich repeat transmembrane neuronal 4 isoform a
           [Homo sapiens]
          Length = 590

 Score = 77.0 bits (188), Expect = 2e-14
 Identities = 61/203 (30%), Positives = 102/203 (50%), Gaps = 24/203 (11%)

Query: 131 CVCLGSSVYCDDIDLEDIPP-LPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLI 189
           C C G  VYC+     DIP  +   +  L  RFN I ++++  F GL +L  + L +N I
Sbjct: 38  CRCDGKIVYCESHAFADIPENISGGSQGLSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYI 97

Query: 190 SSIDNDAFRLLHALQDLILPENQLEAL------PVLPSGIEFLDVRLNRLQSSGIQPAAF 243
           SS+D DAF+ +  L++LIL  N++  L      PV    +  LD+  N+LQ+  +Q   F
Sbjct: 98  SSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPV--PNLRNLDLSYNKLQT--LQSEQF 153

Query: 244 RAMEKLQFLYLSDNLLDSIPGPLPLSLRS---VHLQNNLIETMQRDVFCDPEEHKHTRRQ 300
           + + KL  L+L  N L ++P  +    R+   + L  N + ++ R+ F           +
Sbjct: 154 KGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAG-------LLK 206

Query: 301 LEDIRLDGN---PINLSLFPSAY 320
           L+++ L+ N    IN + FP  +
Sbjct: 207 LKELHLEHNQFSKINFAHFPRLF 229



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 42/136 (30%), Positives = 64/136 (47%), Gaps = 9/136 (6%)

Query: 153 RRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLISSIDNDAFRLLHALQDLILPENQ 212
           R   +L   +NR+  +    F GL KLK + L +N  S I+   F  L  L+ + L  N+
Sbjct: 181 RNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNR 240

Query: 213 L----EALPVLPSGIEFLDVRLNRLQSSGIQPAAFRAMEKLQFLYLSDNLLDSIPGPLP- 267
           +    + L    S +  LD+  N +Q  GI+P  F+ +  LQ L L  N L +I      
Sbjct: 241 IRSISQGLTWTWSSLHNLDLSGNDIQ--GIEPGTFKCLPNLQKLNLDSNKLTNISQETVN 298

Query: 268 --LSLRSVHLQNNLIE 281
             +SL S+ L  N+ E
Sbjct: 299 AWISLISITLSGNMWE 314


>gi|226342935 podocan-like 1 isoform 3 [Homo sapiens]
          Length = 421

 Score = 73.2 bits (178), Expect = 3e-13
 Identities = 65/227 (28%), Positives = 105/227 (46%), Gaps = 25/227 (11%)

Query: 110 PTTAGLLLSSQPNHG-----LPTC--LVCVCLG-SSVYCDDIDLEDIPP-LPRRTAYLYA 160
           P  AGL  ++ P+ G     LP    L C C    +V CD +DL   P  + R   +L  
Sbjct: 20  PPVAGLEDAAFPHLGESLQPLPRACPLRCSCPRVDTVDCDGLDLRVFPDNITRAAQHLSL 79

Query: 161 RFNRISRIRAEDFKGLTKLKRIDLSNNLISS--IDNDAFRLLHALQDLILPENQLEALPV 218
           + N++  +   +   L+ L+ ++L NNLISS  + ++AF  L  LQ L +  N+   +  
Sbjct: 80  QNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAHNKNNLISK 139

Query: 219 LPSG-------IEFLDVRLNRLQSSGIQPAAFRAMEKLQFLYLSDNLLDSIPGPLPLSLR 271
           +P G       +  L ++ N+L  SG+    F  +  L++L LS N L ++P  LP +L 
Sbjct: 140 VPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLA 199

Query: 272 SVHLQNNLIETMQRDVFCDPEEHKHTRRQLEDIRLDGNPINLSLFPS 318
            +HL  N I  ++           H  R L  + L  N +  S  P+
Sbjct: 200 ILHLGRNRIRQVE-------AARLHGARGLRYLLLQHNQLGSSGLPA 239



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 52/186 (27%), Positives = 82/186 (44%), Gaps = 32/186 (17%)

Query: 151 LPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLISSIDNDA-----FRLLHAL-- 203
           LPR  A L+   NRI ++ A    G   L+ + L +N + S    A      R LH L  
Sbjct: 194 LPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHL 253

Query: 204 ----------------QDLILPENQLEALP----VLPSGIEFLDVRLNRLQSSGIQPAAF 243
                           + L+LP N + AL     V   G+  L++  NRL S+ +   AF
Sbjct: 254 YGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAF 313

Query: 244 RAMEKLQFLYLSDNLLDSIPGPLPLSLRSVHLQNNLIETMQRDVFCDPEEHK-----HTR 298
           R +  L+ L L+ N L  +P  LP  LR++ LQ N +  ++ +     ++ +     H R
Sbjct: 314 RRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNR 373

Query: 299 RQLEDI 304
            ++ DI
Sbjct: 374 LRVGDI 379


>gi|188528675 slit homolog 1 [Homo sapiens]
          Length = 1534

 Score = 73.2 bits (178), Expect = 3e-13
 Identities = 67/225 (29%), Positives = 104/225 (46%), Gaps = 41/225 (18%)

Query: 98  PGTPSSNPTMTRPTTAGLLLSSQPNHGLPTC-LVCVCLGSSVYCDDIDLEDIPP-LPRRT 155
           PG  SS   + RP    LL ++    G   C  +C C G++V C    L+ IP  +PR T
Sbjct: 5   PGWGSSAGPV-RPELWLLLWAAAWRLGASACPALCTCTGTTVDCHGTGLQAIPKNIPRNT 63

Query: 156 AYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLISSIDNDAF-------------RLLHA 202
             L    N I+RI   DF GL +L+ + L  N I +++  AF               LH 
Sbjct: 64  ERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHM 123

Query: 203 LQDLI-----------LPENQLEALP--VLPSGIEFLDVRLNRLQSSGIQPAAFRAMEKL 249
           L +L+           L EN ++A+P        +  +++L++ Q S I+  AFRA+  L
Sbjct: 124 LPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGL 183

Query: 250 QFLYLSDNLLDSIP----GPLPLSLRSVHLQNNLIETMQRDVFCD 290
           + L L++N + +IP      +P  LR+  L +N        +FCD
Sbjct: 184 EVLTLNNNNITTIPVSSFNHMP-KLRTFRLHSN-------HLFCD 220



 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 57/168 (33%), Positives = 80/168 (47%), Gaps = 14/168 (8%)

Query: 125 LPTCLV--------CVCLGSSVYCDDIDLEDIPP-LPRRTAYLYARFNRISRIRAEDFKG 175
           +PTC +        C C    V C    L  IP  LP     +    N I  I    F  
Sbjct: 272 VPTCTLSSGSCPAMCTCSNGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSP 331

Query: 176 LTKLKRIDLSNNLISSIDNDAFRLLHALQDLILPENQLEALP-VLPSGIEFLD-VRLNRL 233
             KL+RIDLSNN I+ I  DAF+ L +L  L+L  N++  LP  +  G+  L  + LN  
Sbjct: 332 YRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNAN 391

Query: 234 QSSGIQPAAFRAMEKLQFLYLSDNLLDSIPGPLPLSLRSV---HLQNN 278
           + + I+P AF+ ++ L  L L DN + S+      SLR++   HL  N
Sbjct: 392 KINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN 439



 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 63/208 (30%), Positives = 91/208 (43%), Gaps = 34/208 (16%)

Query: 110 PTTAGLLLSSQPNHGLPTCLVCVCLGSSVYCDDIDLEDIPP-LPRRTAYLYARFNRISRI 168
           P T    L+S+ N  +     C C  + V C  + L  IP  +P+ TA L    N IS +
Sbjct: 496 PGTEDYQLNSECNSDVVCPHKCRCEANVVECSSLKLTKIPERIPQSTAELRLNNNEISIL 555

Query: 169 RAED-FKGLTKLKRIDLSNNLISSIDNDAFRLLHALQDLILPENQLEALPVLPSGIEFLD 227
            A   FK LT LK+I+LSNN +S I++ AF    ++ +L L  NQLE+            
Sbjct: 556 EATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLES------------ 603

Query: 228 VRLNRLQSSGIQPAAFRAMEKLQFLYLSDNLLDSIPGPLPLSLRSVH---LQNNLIETMQ 284
                     I+   FR ++ L+ L L +N +  I       LR+V    L +N I T+ 
Sbjct: 604 ----------IRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVS 653

Query: 285 RDVFCDPEEHKHTRRQLEDIRLDGNPIN 312
              F        T + L  + L  NP N
Sbjct: 654 PGAF-------DTLQSLSTLNLLANPFN 674



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 42/136 (30%), Positives = 62/136 (45%), Gaps = 12/136 (8%)

Query: 131 CVCLGSSVYCDDIDLEDIPP-LPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLI 189
           C CL + V C +  L  +P  +P+    LY   N+ + +  +       L+ +DLSNN I
Sbjct: 738 CACLDTVVRCSNKHLRALPKGIPKNVTELYLDGNQFTLVPGQ-LSTFKYLQLVDLSNNKI 796

Query: 190 SSIDNDAFRLLHALQDLILPENQLEALPVLPSGIEFLDVRLNRLQS------SGIQPAAF 243
           SS+ N +F  +  L  LIL  N L+ +P L     F  +R  RL S      S +Q   F
Sbjct: 797 SSLSNSSFTNMSQLTTLILSYNALQCIPPL----AFQGLRSLRLLSLHGNDISTLQEGIF 852

Query: 244 RAMEKLQFLYLSDNLL 259
             +  L  L +  N L
Sbjct: 853 ADVTSLSHLAIGANPL 868



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 33/97 (34%), Positives = 46/97 (47%), Gaps = 6/97 (6%)

Query: 205 DLILPENQLEALPVLPSGIEFLD-VRLNRLQSSGIQPAAFRAMEKLQFLYLSDNLLDSIP 263
           +L L  NQ   +P   S  ++L  V L+  + S +  ++F  M +L  L LS N L  IP
Sbjct: 765 ELYLDGNQFTLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIP 824

Query: 264 GPLPL----SLRSVHLQNNLIETMQRDVFCDPEEHKH 296
            PL      SLR + L  N I T+Q  +F D     H
Sbjct: 825 -PLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSH 860


>gi|86990456 leucine rich repeat transmembrane neuronal 1 [Homo
           sapiens]
          Length = 522

 Score = 72.0 bits (175), Expect = 7e-13
 Identities = 48/167 (28%), Positives = 88/167 (52%), Gaps = 11/167 (6%)

Query: 130 VCVCLGSSVYCDDIDLEDIPPLPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLI 189
           +C C G  +YC+ ++L + P        L  R+N +S +RA  F GL +L  + L +N I
Sbjct: 42  LCRCEGRLLYCEALNLTEAPHNLSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHI 101

Query: 190 SSIDNDAFRLLHALQDLILPENQLEALP-----VLPSGIEFLDVRLNRLQSSGIQPAAFR 244
            S+  DAF+ L  +++L L  NQ+  LP      +P+ +  +D+  N+LQ+  + P  F 
Sbjct: 102 CSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPN-LRSVDLSYNKLQA--LAPDLFH 158

Query: 245 AMEKLQFLYLSDNLLDSIPGPL---PLSLRSVHLQNNLIETMQRDVF 288
            + KL  L++  N +  +P  +     SL+ + +  N ++++ R+ F
Sbjct: 159 GLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSF 205


>gi|4557543 extracellular matrix protein 2 precursor [Homo sapiens]
          Length = 699

 Score = 72.0 bits (175), Expect = 7e-13
 Identities = 64/192 (33%), Positives = 90/192 (46%), Gaps = 36/192 (18%)

Query: 137 SVYCDDIDLEDIPPL--PRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLISS--I 192
           ++ C +  L  IPPL  P+ T+ L    N I+ I  E F GL  L+R+DLS N I+S  I
Sbjct: 326 TISCINAMLTQIPPLTAPQITS-LELTGNSIASIPDEAFNGLPNLERLDLSKNNITSSGI 384

Query: 193 DNDAFRLLHALQDLILPENQLEALPV-LPSGIEFLDVRLNRLQS---------------- 235
              AF+LL  L  L +  N L  +P  LPS +E L V  N LQ+                
Sbjct: 385 GPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELKVNENNLQAIDEESLSDLNQLVTLE 444

Query: 236 --------SGIQPAAFRAMEKLQFLYLSDNLLDSIPGPLPLSLRSVHLQNNLIETMQRDV 287
                   + + P AF+ ++ L +L L  N    IP  LP S+  ++L+NN IE +    
Sbjct: 445 LEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQGLPGSIEELYLENNQIEEITEIC 504

Query: 288 FCDPEEHKHTRR 299
           F       HTR+
Sbjct: 505 F------NHTRK 510



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 38/135 (28%), Positives = 63/135 (46%), Gaps = 27/135 (20%)

Query: 178 KLKRIDLSNNLISSIDNDAFRLLHALQDLILPENQLEALPVLPSGIEFLDVRLNRLQSSG 237
           ++  ++L+ N I+SI ++AF                  LP     +E LD+  N + SSG
Sbjct: 344 QITSLELTGNSIASIPDEAFN----------------GLP----NLERLDLSKNNITSSG 383

Query: 238 IQPAAFRAMEKLQFLYLSDNLLDSIPGPLPLSLRSVHLQNNLIETMQRDVFCDPEEHKHT 297
           I P AF+ ++KL  L +  N L  IP  LP +L  + +  N ++ +        EE    
Sbjct: 384 IGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELKVNENNLQAID-------EESLSD 436

Query: 298 RRQLEDIRLDGNPIN 312
             QL  + L+GN ++
Sbjct: 437 LNQLVTLELEGNNLS 451


>gi|45505137 podocan [Homo sapiens]
          Length = 661

 Score = 71.6 bits (174), Expect = 9e-13
 Identities = 59/172 (34%), Positives = 81/172 (47%), Gaps = 28/172 (16%)

Query: 145 LEDIPP-LPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLISS--IDNDAFRLLH 201
           LE +P  LPRR   L    N+I+ I  EDF     L+ ++LS N I+S  +  DAFR L 
Sbjct: 419 LERVPSGLPRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRITSPQVHRDAFRKLR 478

Query: 202 ALQDLILPENQLEALPV-LPSGIEFLDVRLN------------------------RLQSS 236
            L+ L L  N+L  LP  LP  +  L V+ N                        RL+S 
Sbjct: 479 LLRSLDLSGNRLHTLPPGLPRNVHVLKVKRNELAALARGALVGMAQLRELYLTSNRLRSR 538

Query: 237 GIQPAAFRAMEKLQFLYLSDNLLDSIPGPLPLSLRSVHLQNNLIETMQRDVF 288
            + P A+  +  LQ L ++ N L  IP  LP SL  ++LQNN I  +  + F
Sbjct: 539 ALGPRAWVDLAHLQLLDIAGNQLTEIPEGLPESLEYLYLQNNKISAVPANAF 590



 Score = 66.2 bits (160), Expect = 4e-11
 Identities = 65/248 (26%), Positives = 101/248 (40%), Gaps = 40/248 (16%)

Query: 83  LAPATSISPAKSTTAPGTPSSNPTMTRPTTAG-------LLLSSQ---PNHGLPTC-LVC 131
           L P   + P  +  APG   S      P           L+LS +   P     +C   C
Sbjct: 61  LPPQLHLGPVLAVRAPGFGRSGGHSLSPEENEFAEEEPVLVLSPEEPGPGPAAVSCPRDC 120

Query: 132 VCLGSSVY-CDDIDLEDIP-PLPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLI 189
            C    V  C  IDL + P  LP  T +L  + N++ +I  E+   L +L+ ++L NN +
Sbjct: 121 ACSQEGVVDCGGIDLREFPGDLPEHTNHLSLQNNQLEKIYPEELSRLHRLETLNLQNNRL 180

Query: 190 SS--IDNDAFRLLHALQDLILPENQLEALP-VLPSGIEFLD------------------- 227
           +S  +   AF  L  L  L L  N+L   P  LP+ +  +D                   
Sbjct: 181 TSRGLPEKAFEHLTNLNYLYLANNKLTLAPRFLPNALISVDFAANYLTKIYGLTFGQKPN 240

Query: 228 -----VRLNRLQSSGIQPAAFRAMEKLQFLYLSDNLLDSIPGPLPLSLRSVHLQNNLIET 282
                +  N+L  +G+    F     ++ L LS N L  +P  LP +L  +HL+NN +E 
Sbjct: 241 LRSVYLHNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPALYKLHLKNNKLEK 300

Query: 283 MQRDVFCD 290
           +    F +
Sbjct: 301 IPPGAFSE 308



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 50/188 (26%), Positives = 88/188 (46%), Gaps = 34/188 (18%)

Query: 151 LPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLISS--IDNDAFRLLHALQDLIL 208
           LP     L+ + N++ +I    F  L+ L+ + L NN ++   +DN+ F  L +L+ L L
Sbjct: 284 LPPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDL 343

Query: 209 PENQLEALPV-LPSGI------------------------EFLDVRLNRLQSSGIQPAAF 243
             N L  +P  LP  +                        E+L +  N+L+  GI P AF
Sbjct: 344 SSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAF 403

Query: 244 RAMEKLQFLYLSDNLLDSIPGPLPLSLRSVHLQNNLIETMQRDVFCDPEEHKHTRRQLED 303
           + +++L  ++L +N L+ +P  LP  +R++ + +N I  + R+ F        T   LE+
Sbjct: 404 QGLKRLHTVHLYNNALERVPSGLPRRVRTLMILHNQITGIGREDFA-------TTYFLEE 456

Query: 304 IRLDGNPI 311
           + L  N I
Sbjct: 457 LNLSYNRI 464



 Score = 37.7 bits (86), Expect = 0.014
 Identities = 37/142 (26%), Positives = 62/142 (43%), Gaps = 28/142 (19%)

Query: 145 LEDIPP-LPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLISS--IDNDAFRLLH 201
           L  +PP LPR    L  + N ++ +      G+ +L+ + L++N + S  +   A+  L 
Sbjct: 490 LHTLPPGLPRNVHVLKVKRNELAALARGALVGMAQLRELYLTSNRLRSRALGPRAWVDLA 549

Query: 202 ALQDLILPENQLEALPV-LPSGIEFLDV------------------------RLNRLQSS 236
            LQ L +  NQL  +P  LP  +E+L +                        R N+L   
Sbjct: 550 HLQLLDIAGNQLTEIPEGLPESLEYLYLQNNKISAVPANAFDSTPNLKGIFLRFNKLAVG 609

Query: 237 GIQPAAFRAMEKLQFLYLSDNL 258
            +  +AFR ++ LQ L +  NL
Sbjct: 610 SVVDSAFRRLKHLQVLDIEGNL 631


>gi|7662102 leucine rich repeat transmembrane neuronal 2 [Homo
           sapiens]
          Length = 516

 Score = 71.2 bits (173), Expect = 1e-12
 Identities = 55/196 (28%), Positives = 90/196 (45%), Gaps = 10/196 (5%)

Query: 101 PSSNPTMTRPTTAGLLLSSQPNHGLPTCLVCVCLGSSVYCDDIDLEDIP-PLPRRTAYLY 159
           P   P +       ++L   P  G+     C C     YCD      +P    + +  L 
Sbjct: 8   PLGAPMLAAIYAMSMVLKMLPALGMACPPKCRCEKLLFYCDSQGFHSVPNATDKGSLGLS 67

Query: 160 ARFNRISRIRAEDFKGLTKLKRIDLSNNLISSIDNDAFRLLHALQDLILPENQLEALP-- 217
            R N I+ +  + F   ++L  + L +N IS++  DAF+ L+ L++LIL  N++  LP  
Sbjct: 68  LRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNT 127

Query: 218 --VLPSGIEFLDVRLNRLQSSGIQPAAFRAMEKLQFLYLSDNLLDSIPGPLPLSLRSVH- 274
                  ++ LD+  N+L  S + P  F  + KLQ L+L  N L +IP  L    RS+  
Sbjct: 128 TFTQLINLQNLDLSFNQL--SSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEF 185

Query: 275 --LQNNLIETMQRDVF 288
             L  N + ++ R+ F
Sbjct: 186 LDLSTNRLRSLARNGF 201



 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 55/170 (32%), Positives = 86/170 (50%), Gaps = 13/170 (7%)

Query: 119 SQPNHGLPTCLVCVCLGSSV---YCDDIDLEDIPPLPRRTAYLYARFNRISRIRAEDFKG 175
           SQ  H +P       LG S+   +  +++ +      + T +L+   N+IS ++ + F+G
Sbjct: 49  SQGFHSVPNATDKGSLGLSLRHNHITELERDQFASFSQLT-WLHLDHNQISTVKEDAFQG 107

Query: 176 LTKLKRIDLSNNLISSIDNDAFRLLHALQDLILPENQLEAL-PVLPSG---IEFLDVRLN 231
           L KLK + LS+N I  + N  F  L  LQ+L L  NQL +L P L  G   ++ L +R N
Sbjct: 108 LYKLKELILSSNKIFYLPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSN 167

Query: 232 RLQSSGIQPAAFRAMEKLQFLYLSDNLLDSIPG---PLPLSLRSVHLQNN 278
            L++  I    F     L+FL LS N L S+        + LR +HL++N
Sbjct: 168 SLRT--IPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHN 215



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 42/141 (29%), Positives = 64/141 (45%), Gaps = 11/141 (7%)

Query: 153 RRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLISSIDNDAFRLLHALQDLILPENQ 212
           R   +L    NR+  +    F GL KL+ + L +N ++ I+   F  L +L  L L  N+
Sbjct: 181 RSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNK 240

Query: 213 LEALPVLPSGIEFLDVRLNRLQSSG-----IQPAAFRAMEKLQFLYLSDNLLDSIPGPLP 267
           +     L  G+E+    L +L  +G     I    F  M  L+ L + +N L+S+   + 
Sbjct: 241 ISN---LTCGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKIL 297

Query: 268 LSLRS---VHLQNNLIETMQR 285
            SLRS   V L  NL E   R
Sbjct: 298 NSLRSLTTVGLSGNLWECSAR 318


>gi|40217817 slit and trk like 1 protein [Homo sapiens]
          Length = 696

 Score = 68.9 bits (167), Expect = 6e-12
 Identities = 72/248 (29%), Positives = 107/248 (43%), Gaps = 32/248 (12%)

Query: 61  DLSNYEELTDYGDQLPEVKVTSLAPATSISPAKSTTAP--GTPSSNPT-----------M 107
           DL   +   D     P  +  + AP    +P K+       TP S P             
Sbjct: 259 DLCPLKNRVDSSLPAPPAQEETFAPGPLPTPFKTNGQEDHATPGSAPNGGTKIPGNWQIK 318

Query: 108 TRPTTAGLLLSSQPN---HGLPTCLVCVC-----LGSSVYCDDID---LEDIPPLPRRTA 156
            RPT A    SS+     + LP    C C      G  + C++ +   L D+ P      
Sbjct: 319 IRPTAAIATGSSRNKPLANSLPCPGGCSCDHIPGSGLKMNCNNRNVSSLADLKPKLSNVQ 378

Query: 157 YLYARFNRISRIRAEDFKGLTKLKRIDLSNNLISSIDNDAFRLLHALQDLILPENQLEAL 216
            L+ R N+I  IR   F     L  +DL NN I++++N+ F+ L  L+ L +  N L+ L
Sbjct: 379 ELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTL 438

Query: 217 P----VLPSGIEFLDVRLNRLQSSGIQPAAFRAMEKLQFLYLSDNLLDSIPGPL--PLSL 270
                     +E+L+V  N +Q   I P  F AM KL+ L L++NLL S+P  +   +SL
Sbjct: 439 SREKFAGLQNLEYLNVEYNAIQL--ILPGTFNAMPKLRILILNNNLLRSLPVDVFAGVSL 496

Query: 271 RSVHLQNN 278
             + L NN
Sbjct: 497 SKLSLHNN 504



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 30/83 (36%), Positives = 45/83 (54%), Gaps = 7/83 (8%)

Query: 158 LYARFNRISRIRAEDFKGLTKLKRIDLSNNLISSIDNDAFRLLHALQDLILPENQLEALP 217
           L+   N+I   R + F GL  L+ +    NL+  ID  AF+ L+ L+ LIL +N +  LP
Sbjct: 111 LHINNNKIKSFRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLP 170

Query: 218 V-----LPSGIEFLDVRLNRLQS 235
                 +P  I  LD+R NRL++
Sbjct: 171 ANVFQYVP--ITHLDLRGNRLKT 191



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 31/133 (23%), Positives = 65/133 (48%), Gaps = 8/133 (6%)

Query: 157 YLYARFNRISRIRAEDFKGLTKLKRIDLSNNLISSIDNDAFRLLHALQDLILPENQLEAL 216
           +L+   N ++R+   +F        + + NN +  I   AF  L  ++ L +  N++++ 
Sbjct: 62  HLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSF 121

Query: 217 PVLP----SGIEFLDVRLNRLQSSGIQPAAFRAMEKLQFLYLSDNLLDSIPGPL--PLSL 270
                     +E+L    N L+   I P AF+ + KL+ L L+DNL+ ++P  +   + +
Sbjct: 122 RKQTFLGLDDLEYLQADFNLLRD--IDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPI 179

Query: 271 RSVHLQNNLIETM 283
             + L+ N ++T+
Sbjct: 180 THLDLRGNRLKTL 192


>gi|11321571 slit homolog 3 [Homo sapiens]
          Length = 1523

 Score = 68.9 bits (167), Expect = 6e-12
 Identities = 57/171 (33%), Positives = 83/171 (48%), Gaps = 8/171 (4%)

Query: 116 LLSSQPNHGLPTCLVCVCLGSSVYCDDIDLEDIPP-LPRRTAYLYARFNRISRIRAEDFK 174
           +LS  P    PT   C C  +SV C  + L  +P  +PR    L    N I+RI   DF 
Sbjct: 25  VLSGPPAVACPT--KCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFA 82

Query: 175 GLTKLKRIDLSNNLISSIDNDAFRLLHALQDLILPENQLEALPVL--PSGIEFLDVRLNR 232
           GL  L+ + L +N +S I+  AF+ L  L+ L L +N+L+ LP L   S  +   + L+ 
Sbjct: 83  GLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSE 142

Query: 233 LQSSGIQPAAFRAMEKLQFLYLSDNLLDSIPGPLPLSLRSVH---LQNNLI 280
            Q  GI   AFR +  ++ L L +N +  I      +LR +    L NN I
Sbjct: 143 NQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNI 193



 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 54/154 (35%), Positives = 77/154 (50%), Gaps = 6/154 (3%)

Query: 131 CVCLGSSVYCDDIDLEDIPP-LPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLI 189
           C C  + V C    L +IP  LP     +    N I  I A  F    KLKRID+S N I
Sbjct: 284 CTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQI 343

Query: 190 SSIDNDAFRLLHALQDLILPENQL-EALPVLPSGIEFLD-VRLNRLQSSGIQPAAFRAME 247
           S I  DAF+ L +L  L+L  N++ E    L  G+  L  + LN  + + ++   F+ ++
Sbjct: 344 SDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQ 403

Query: 248 KLQFLYLSDNLLDSIPGPL--PL-SLRSVHLQNN 278
            L  L L DN L +I   L  PL S++++HL  N
Sbjct: 404 NLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQN 437



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 50/157 (31%), Positives = 78/157 (49%), Gaps = 11/157 (7%)

Query: 131 CVCLGSSVYCDDIDLEDIPP-LPRRTAYLYARFNRISRIRAED-FKGLTKLKRIDLSNNL 188
           C C G+ V C +  L  IP  LP     L    N +S + A   FK L  L++I+LSNN 
Sbjct: 509 CRCEGTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNK 568

Query: 189 ISSIDNDAFRLLHALQDLILPENQLEALPVLP----SGIEFLDVRLNRLQSSGIQPAAFR 244
           I  +   AF    ++Q+L+L  NQLE +        SG++ L +R N +    +    F 
Sbjct: 569 IKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLI--GCVSNDTFA 626

Query: 245 AMEKLQFLYLSDNLLDSI-PGPLP--LSLRSVHLQNN 278
            +  ++ L L DN + +I PG     +SL +++L +N
Sbjct: 627 GLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSN 663



 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 42/132 (31%), Positives = 61/132 (46%), Gaps = 4/132 (3%)

Query: 131 CVCLGSSVYCDDIDLEDIPP-LPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLI 189
           C C+ + V C +  L  +P  +P+    LY   N ++ +  E    L  L  IDLSNN I
Sbjct: 729 CTCMETVVRCSNKGLRALPRGMPKDVTELYLEGNHLTAVPRE-LSALRHLTLIDLSNNSI 787

Query: 190 SSIDNDAFRLLHALQDLILPENQLEALPVLP-SGIEFLDV-RLNRLQSSGIQPAAFRAME 247
           S + N  F  +  L  LIL  N+L  +PV   +G+  L V  L+    S +   +F  + 
Sbjct: 788 SMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLT 847

Query: 248 KLQFLYLSDNLL 259
            L  L L  N L
Sbjct: 848 SLSHLALGTNPL 859



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 39/133 (29%), Positives = 62/133 (46%), Gaps = 9/133 (6%)

Query: 163 NRISRIRAEDFKGLTKLKRIDLSNNLISSIDNDAFRLLHALQDLILPENQLEALPVLPSG 222
           N+I  I  + F+G+T +K + L NN IS I++ AFR L  L+ L L  N +  + ++ S 
Sbjct: 143 NQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRI-LVTSF 201

Query: 223 IEFLDVRLNRLQSSGIQPAAFRAMEKLQFLYLSDNLLD-SIPGPLPLSLRSVHLQNNLIE 281
                +R  RL S+ +      A       +LSD L      G   L +  VHL+   + 
Sbjct: 202 NHMPKIRTLRLHSNHLYCDCHLA-------WLSDWLRQRRTVGQFTLCMAPVHLRGFNVA 254

Query: 282 TMQRDVFCDPEEH 294
            +Q+  +  P  H
Sbjct: 255 DVQKKEYVCPAPH 267


>gi|40217823 SLIT and NTRK-like family, member 5 [Homo sapiens]
          Length = 958

 Score = 68.6 bits (166), Expect = 8e-12
 Identities = 71/229 (31%), Positives = 105/229 (45%), Gaps = 36/229 (15%)

Query: 80  VTSLAPATS------ISPAKSTTAPGTPSSNPTMTRPT------TAGLLLSSQPNHGLPT 127
           V S+A ++S      + P K T  P  P   PT  +P+        G  ++ Q    +P 
Sbjct: 313 VNSVATSSSAVYKPPLKPPKGTRQPNKPRVRPTSRQPSKDLGYSNYGPSIAYQTKSPVPL 372

Query: 128 -C-LVCVC------LGSSVYCDDIDLEDIP---PLPRRTAYLYARFNRISRIRAEDFKGL 176
            C   C C      LG +V C +  +E I    P P     +Y   N I+ +R  DF   
Sbjct: 373 ECPTACSCNLQISDLGLNVNCQERKIESIAELQPKPYNPKKMYLTENYIAVVRRTDFLEA 432

Query: 177 TKLKRIDLSNNLISSIDNDAFRLLHALQDLILPENQLEAL-PVLPSG---IEFLDVRLNR 232
           T L  + L NN IS I + AF  L  L+ L L  N++E L P L  G   +++L ++ N 
Sbjct: 433 TGLDLLHLGNNRISMIQDRAFGDLTNLRRLYLNGNRIERLSPELFYGLQSLQYLFLQYNL 492

Query: 233 LQSSGIQPAAFRAMEKLQFLYLSDNLLDSIPGP-------LPLSLRSVH 274
           ++   IQ   F  +  LQ L+L++NLL ++P         L L+LRS H
Sbjct: 493 IRE--IQSGTFDPVPNLQLLFLNNNLLQAMPSGVFSGLTLLRLNLRSNH 539



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 50/147 (34%), Positives = 73/147 (49%), Gaps = 11/147 (7%)

Query: 137 SVYCDD---IDLEDIPPLPRRTAY-LYARFNRISRIRAEDFKGLTKLKRIDLSNNLISSI 192
           +V C++   I L +I P PR   Y L    N ++R+   +F   T    + L +N+I  I
Sbjct: 62  TVSCENRGIISLSEISP-PRFPIYHLLLSGNLLNRLYPNEFVNYTGASILHLGSNVIQDI 120

Query: 193 DNDAFRLLHALQDLILPENQLEALP----VLPSGIEFLDVRLNRLQSSGIQPAAFRAMEK 248
           +  AF  L  L+ L L  N+LE L     +    +E+L V  N +  S I+P AF  +  
Sbjct: 121 ETGAFHGLRGLRRLHLNNNKLELLRDDTFLGLENLEYLQVDYNYI--SVIEPNAFGKLHL 178

Query: 249 LQFLYLSDNLLDSIPGPLPLSLRSVHL 275
           LQ L L+DNLL S+P  L   +   HL
Sbjct: 179 LQVLILNDNLLSSLPNNLFRFVPLTHL 205



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 37/107 (34%), Positives = 58/107 (54%), Gaps = 12/107 (11%)

Query: 158 LYARFNRISRIRAEDFKGLTKLKRIDLSNNLISSIDNDAFRLLHALQDLILPENQLEALP 217
           L+   N++  +R + F GL  L+ + +  N IS I+ +AF  LH LQ LIL +N L +LP
Sbjct: 134 LHLNNNKLELLRDDTFLGLENLEYLQVDYNYISVIEPNAFGKLHLLQVLILNDNLLSSLP 193

Query: 218 -----VLPSGIEFLDVRLNRLQSSGIQP--AAFRAMEKLQFLYLSDN 257
                 +P  +  LD+R NRL+   + P     + M+K+  L L +N
Sbjct: 194 NNLFRFVP--LTHLDLRGNRLK---LLPYVGLLQHMDKVVELQLEEN 235


>gi|38202222 fibronectin leucine rich transmembrane protein 3
           precursor [Homo sapiens]
          Length = 649

 Score = 67.8 bits (164), Expect = 1e-11
 Identities = 60/190 (31%), Positives = 93/190 (48%), Gaps = 18/190 (9%)

Query: 130 VCVCLGSSVYCDDIDLEDIPP-LPRRTAYLYARFNRISRIRA-EDFKGLTKLKRIDLSNN 187
           VC C    +YC+D  L  IP  +P     LY + N+I+      D K L K++RI L +N
Sbjct: 34  VCRCDAGFIYCNDRFLTSIPTGIPEDATTLYLQNNQINNAGIPSDLKNLLKVERIYLYHN 93

Query: 188 LISSIDNDAFRLLHALQDLILPENQL-----EALPVLPSGIEFLDVRLNRLQSSGIQPAA 242
              S+D     L   +++L L EN +     ++L  +P  +E L +  N + +  I+  A
Sbjct: 94  ---SLDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPY-LEELHLDDNSVSAVSIEEGA 149

Query: 243 FRAMEKLQFLYLSDNLLDSIPGPLPLSLRSVHLQNNLIETMQRDVFCDPEEHKHTRRQLE 302
           FR    L+ L+LS N L +IP  LP ++  + L +N I T+       P     T   L+
Sbjct: 150 FRDSNYLRLLFLSRNHLSTIPWGLPRTIEELRLDDNRISTIS-----SPSLQGLT--SLK 202

Query: 303 DIRLDGNPIN 312
            + LDGN +N
Sbjct: 203 RLVLDGNLLN 212



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 39/115 (33%), Positives = 57/115 (49%), Gaps = 2/115 (1%)

Query: 151 LPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLISS--IDNDAFRLLHALQDLIL 208
           LPR    L    NRIS I +   +GLT LKR+ L  NL+++  + +  F  L  L +L L
Sbjct: 173 LPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSL 232

Query: 209 PENQLEALPVLPSGIEFLDVRLNRLQSSGIQPAAFRAMEKLQFLYLSDNLLDSIP 263
             N L A PV   G     + L     + + P AF  + +L  L +S+N L ++P
Sbjct: 233 VRNSLTAAPVNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLP 287



 Score = 36.6 bits (83), Expect = 0.032
 Identities = 20/54 (37%), Positives = 30/54 (55%)

Query: 158 LYARFNRISRIRAEDFKGLTKLKRIDLSNNLISSIDNDAFRLLHALQDLILPEN 211
           LY + N I+R+    F  L +L R+D+SNN +S++    F  L  +  LIL  N
Sbjct: 252 LYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLILRNN 305


>gi|7019383 fibronectin leucine rich transmembrane protein 3
           precursor [Homo sapiens]
          Length = 649

 Score = 67.8 bits (164), Expect = 1e-11
 Identities = 60/190 (31%), Positives = 93/190 (48%), Gaps = 18/190 (9%)

Query: 130 VCVCLGSSVYCDDIDLEDIPP-LPRRTAYLYARFNRISRIRA-EDFKGLTKLKRIDLSNN 187
           VC C    +YC+D  L  IP  +P     LY + N+I+      D K L K++RI L +N
Sbjct: 34  VCRCDAGFIYCNDRFLTSIPTGIPEDATTLYLQNNQINNAGIPSDLKNLLKVERIYLYHN 93

Query: 188 LISSIDNDAFRLLHALQDLILPENQL-----EALPVLPSGIEFLDVRLNRLQSSGIQPAA 242
              S+D     L   +++L L EN +     ++L  +P  +E L +  N + +  I+  A
Sbjct: 94  ---SLDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPY-LEELHLDDNSVSAVSIEEGA 149

Query: 243 FRAMEKLQFLYLSDNLLDSIPGPLPLSLRSVHLQNNLIETMQRDVFCDPEEHKHTRRQLE 302
           FR    L+ L+LS N L +IP  LP ++  + L +N I T+       P     T   L+
Sbjct: 150 FRDSNYLRLLFLSRNHLSTIPWGLPRTIEELRLDDNRISTIS-----SPSLQGLT--SLK 202

Query: 303 DIRLDGNPIN 312
            + LDGN +N
Sbjct: 203 RLVLDGNLLN 212



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 39/115 (33%), Positives = 57/115 (49%), Gaps = 2/115 (1%)

Query: 151 LPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLISS--IDNDAFRLLHALQDLIL 208
           LPR    L    NRIS I +   +GLT LKR+ L  NL+++  + +  F  L  L +L L
Sbjct: 173 LPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSL 232

Query: 209 PENQLEALPVLPSGIEFLDVRLNRLQSSGIQPAAFRAMEKLQFLYLSDNLLDSIP 263
             N L A PV   G     + L     + + P AF  + +L  L +S+N L ++P
Sbjct: 233 VRNSLTAAPVNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLP 287



 Score = 36.6 bits (83), Expect = 0.032
 Identities = 20/54 (37%), Positives = 30/54 (55%)

Query: 158 LYARFNRISRIRAEDFKGLTKLKRIDLSNNLISSIDNDAFRLLHALQDLILPEN 211
           LY + N I+R+    F  L +L R+D+SNN +S++    F  L  +  LIL  N
Sbjct: 252 LYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLILRNN 305


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.138    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,441,914
Number of Sequences: 37866
Number of extensions: 650910
Number of successful extensions: 5002
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 189
Number of HSP's successfully gapped in prelim test: 114
Number of HSP's that attempted gapping in prelim test: 3346
Number of HSP's gapped (non-prelim): 1261
length of query: 332
length of database: 18,247,518
effective HSP length: 103
effective length of query: 229
effective length of database: 14,347,320
effective search space: 3285536280
effective search space used: 3285536280
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.