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Search of human proteins with 74136883
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|74136883 heterogeneous nuclear ribonucleoprotein U isoform a
[Homo sapiens]
(825 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|74136883 heterogeneous nuclear ribonucleoprotein U isoform a ... 1704 0.0
gi|14141161 heterogeneous nuclear ribonucleoprotein U isoform b ... 1653 0.0
gi|21536326 heterogeneous nuclear ribonucleoprotein U-like 1 iso... 617 e-176
gi|118601081 heterogeneous nuclear ribonucleoprotein U-like 2 [H... 587 e-167
gi|21536320 heterogeneous nuclear ribonucleoprotein U-like 1 iso... 584 e-166
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 89 2e-17
gi|4826686 DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 [Homo sapiens] 88 4e-17
gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo sap... 74 7e-13
gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b... 70 6e-12
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma... 66 2e-10
gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isofor... 65 3e-10
gi|4504447 heterogeneous nuclear ribonucleoprotein A2/B1 isoform... 65 3e-10
gi|109452587 family with sequence similarity 98, member B isofor... 64 6e-10
gi|12056465 fibrillarin [Homo sapiens] 59 2e-08
gi|4504445 heterogeneous nuclear ribonucleoprotein A1 isoform a ... 58 3e-08
gi|166795264 AE binding protein 2 isoform b [Homo sapiens] 58 4e-08
gi|166795262 AE binding protein 2 isoform a [Homo sapiens] 58 4e-08
gi|56699482 hypothetical protein LOC25940 [Homo sapiens] 56 1e-07
gi|21735415 centromere protein B [Homo sapiens] 56 2e-07
gi|27894378 chloride intracellular channel 6 [Homo sapiens] 55 2e-07
gi|156151396 heterogeneous nuclear ribonucleoprotein R isoform 3... 55 3e-07
gi|156151394 heterogeneous nuclear ribonucleoprotein R isoform 1... 55 3e-07
gi|156151392 heterogeneous nuclear ribonucleoprotein R isoform 4... 55 3e-07
gi|5031755 heterogeneous nuclear ribonucleoprotein R isoform 2 [... 55 3e-07
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 55 3e-07
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 55 3e-07
gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo sap... 55 3e-07
gi|158966674 proline-rich protein HaeIII subfamily 2 [Homo sapiens] 54 5e-07
gi|4826944 proline-rich protein HaeIII subfamily 2 [Homo sapiens] 54 5e-07
gi|228008295 synaptotagmin binding, cytoplasmic RNA interacting ... 54 6e-07
>gi|74136883 heterogeneous nuclear ribonucleoprotein U isoform a
[Homo sapiens]
Length = 825
Score = 1704 bits (4413), Expect = 0.0
Identities = 825/825 (100%), Positives = 825/825 (100%)
Query: 1 MSSSPVNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSL 60
MSSSPVNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSL
Sbjct: 1 MSSSPVNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSL 60
Query: 61 DLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGP 120
DLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGP
Sbjct: 61 DLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGP 120
Query: 121 MEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAA 180
MEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAA
Sbjct: 121 MEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAA 180
Query: 181 KEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGKKKAEGGGGGGRPGAPAAGDGKTEQKGG 240
KEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGKKKAEGGGGGGRPGAPAAGDGKTEQKGG
Sbjct: 181 KEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGKKKAEGGGGGGRPGAPAAGDGKTEQKGG 240
Query: 241 DKKRGVKRPREDHGRGYFEYIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFK 300
DKKRGVKRPREDHGRGYFEYIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFK
Sbjct: 241 DKKRGVKRPREDHGRGYFEYIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFK 300
Query: 301 ISRDRLSASSLTMESFAFLWAGGRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVR 360
ISRDRLSASSLTMESFAFLWAGGRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVR
Sbjct: 301 ISRDRLSASSLTMESFAFLWAGGRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVR 360
Query: 361 IGWSLTTSGMLLGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVITCFANFESDEVELS 420
IGWSLTTSGMLLGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVITCFANFESDEVELS
Sbjct: 361 IGWSLTTSGMLLGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVITCFANFESDEVELS 420
Query: 421 YAKNGQDLGVAFKISKEVLAGRPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVP 480
YAKNGQDLGVAFKISKEVLAGRPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVP
Sbjct: 421 YAKNGQDLGVAFKISKEVLAGRPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVP 480
Query: 481 LEDRVRGPKGPEEKKDCEVVMMIGLPGAGKTTWVTKHAAENPGKYNILGTNTIMDKMMVA 540
LEDRVRGPKGPEEKKDCEVVMMIGLPGAGKTTWVTKHAAENPGKYNILGTNTIMDKMMVA
Sbjct: 481 LEDRVRGPKGPEEKKDCEVVMMIGLPGAGKTTWVTKHAAENPGKYNILGTNTIMDKMMVA 540
Query: 541 GFKKQMADTGKLNTLLQRAPQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQ 600
GFKKQMADTGKLNTLLQRAPQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQ
Sbjct: 541 GFKKQMADTGKLNTLLQRAPQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQ 600
Query: 601 RKAVVVCPKDEDYKQRTQKKAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKE 660
RKAVVVCPKDEDYKQRTQKKAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKE
Sbjct: 601 RKAVVVCPKDEDYKQRTQKKAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKE 660
Query: 661 EAQKLLEQYKEESKKALPPEKKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNFR 720
EAQKLLEQYKEESKKALPPEKKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNFR
Sbjct: 661 EAQKLLEQYKEESKKALPPEKKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNFR 720
Query: 721 GGAPGNRGGYNRRGNMPQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRG 780
GGAPGNRGGYNRRGNMPQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRG
Sbjct: 721 GGAPGNRGGYNRRGNMPQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRG 780
Query: 781 NYNQNFRGRGNNRGYKNQSQGYNQWQQGQFWGQKPWSQHYHQGYY 825
NYNQNFRGRGNNRGYKNQSQGYNQWQQGQFWGQKPWSQHYHQGYY
Sbjct: 781 NYNQNFRGRGNNRGYKNQSQGYNQWQQGQFWGQKPWSQHYHQGYY 825
>gi|14141161 heterogeneous nuclear ribonucleoprotein U isoform b
[Homo sapiens]
Length = 806
Score = 1653 bits (4280), Expect = 0.0
Identities = 806/825 (97%), Positives = 806/825 (97%), Gaps = 19/825 (2%)
Query: 1 MSSSPVNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSL 60
MSSSPVNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSL
Sbjct: 1 MSSSPVNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSL 60
Query: 61 DLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGP 120
DLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGP
Sbjct: 61 DLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGP 120
Query: 121 MEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAA 180
MEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAA
Sbjct: 121 MEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAA 180
Query: 181 KEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGKKKAEGGGGGGRPGAPAAGDGKTEQKGG 240
KEAAGKSSGPTSLFAVTVAPPGARQGQQQAGG DGKTEQKGG
Sbjct: 181 KEAAGKSSGPTSLFAVTVAPPGARQGQQQAGG-------------------DGKTEQKGG 221
Query: 241 DKKRGVKRPREDHGRGYFEYIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFK 300
DKKRGVKRPREDHGRGYFEYIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFK
Sbjct: 222 DKKRGVKRPREDHGRGYFEYIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFK 281
Query: 301 ISRDRLSASSLTMESFAFLWAGGRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVR 360
ISRDRLSASSLTMESFAFLWAGGRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVR
Sbjct: 282 ISRDRLSASSLTMESFAFLWAGGRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVR 341
Query: 361 IGWSLTTSGMLLGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVITCFANFESDEVELS 420
IGWSLTTSGMLLGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVITCFANFESDEVELS
Sbjct: 342 IGWSLTTSGMLLGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVITCFANFESDEVELS 401
Query: 421 YAKNGQDLGVAFKISKEVLAGRPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVP 480
YAKNGQDLGVAFKISKEVLAGRPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVP
Sbjct: 402 YAKNGQDLGVAFKISKEVLAGRPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVP 461
Query: 481 LEDRVRGPKGPEEKKDCEVVMMIGLPGAGKTTWVTKHAAENPGKYNILGTNTIMDKMMVA 540
LEDRVRGPKGPEEKKDCEVVMMIGLPGAGKTTWVTKHAAENPGKYNILGTNTIMDKMMVA
Sbjct: 462 LEDRVRGPKGPEEKKDCEVVMMIGLPGAGKTTWVTKHAAENPGKYNILGTNTIMDKMMVA 521
Query: 541 GFKKQMADTGKLNTLLQRAPQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQ 600
GFKKQMADTGKLNTLLQRAPQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQ
Sbjct: 522 GFKKQMADTGKLNTLLQRAPQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQ 581
Query: 601 RKAVVVCPKDEDYKQRTQKKAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKE 660
RKAVVVCPKDEDYKQRTQKKAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKE
Sbjct: 582 RKAVVVCPKDEDYKQRTQKKAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKE 641
Query: 661 EAQKLLEQYKEESKKALPPEKKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNFR 720
EAQKLLEQYKEESKKALPPEKKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNFR
Sbjct: 642 EAQKLLEQYKEESKKALPPEKKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNFR 701
Query: 721 GGAPGNRGGYNRRGNMPQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRG 780
GGAPGNRGGYNRRGNMPQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRG
Sbjct: 702 GGAPGNRGGYNRRGNMPQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRG 761
Query: 781 NYNQNFRGRGNNRGYKNQSQGYNQWQQGQFWGQKPWSQHYHQGYY 825
NYNQNFRGRGNNRGYKNQSQGYNQWQQGQFWGQKPWSQHYHQGYY
Sbjct: 762 NYNQNFRGRGNNRGYKNQSQGYNQWQQGQFWGQKPWSQHYHQGYY 806
>gi|21536326 heterogeneous nuclear ribonucleoprotein U-like 1
isoform a [Homo sapiens]
Length = 856
Score = 617 bits (1591), Expect = e-176
Identities = 362/795 (45%), Positives = 471/795 (59%), Gaps = 115/795 (14%)
Query: 6 VNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSLDLGGD 65
++V++LKV+EL+EEL++R L +GLKAEL ERLQAAL+ EE ++ D
Sbjct: 1 MDVRRLKVNELREELQRRGLDTRGLKAELAERLQAALEAEEPDDERELD--------ADD 52
Query: 66 SAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGPMEEEE 125
GR G E+ GG E E + G+ E G +G G +
Sbjct: 53 EPGRPGHINEEVETEGGSELEGTAQPPPPGL-------QPHAEPGGYSG--PDGHYAMDN 103
Query: 126 AASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAAKEAAG 185
+++ D Q ++ E+E G E +P +QQQ + +
Sbjct: 104 ITRQNQFYDTQVIKQ-ENESGYER--------------RPLEMEQQQAYRPE---MKTEM 145
Query: 186 KSSGPTSLFAVTVAPPGARQGQQQAGGKKKAEGGGGGGRPGAPAAGDGKTEQKGGDKKRG 245
K PTS PP A Q + Q+ +KR
Sbjct: 146 KQGAPTSFL-----PPEASQLKPD--------------------------RQQFQSRKRP 174
Query: 246 VKRPREDHGRGYFEYIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFKISRDR 305
+ E+ GRGYFE+ E+ R +SPQPP EE+++ FDDT+V +DTYNCDLHFK++RDR
Sbjct: 175 YE---ENRGRGYFEHREDR---RGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDR 228
Query: 306 LSASSLTMESFAFLWAGGRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVRIGWSL 365
S LT+E FA+LW+G RASYGV +G+VCFEMK+ E+I V+HL + + D H VRIGWSL
Sbjct: 229 SSGYPLTIEGFAYLWSGARASYGVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSL 288
Query: 366 TTSGMLLGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVITCFANFE-SDEVELSYAKN 424
+ LGEE FSYGY G K+ N E+YG+KF ENDVI CFA+FE ++VELS+ KN
Sbjct: 289 DSCSTQLGEEPFSYGYGGTGKKSTNSRFENYGDKFAENDVIGCFADFECGNDVELSFTKN 348
Query: 425 GQDLGVAFKISKEVLAGRPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVPLEDR 484
G+ +G+AF+I KE L G+ L+PHVL NCAVEFNFGQ+ +PY + +TFIQ++PL +R
Sbjct: 349 GKWMGIAFRIQKEALGGQALYPHVLVKNCAVEFNFGQRAEPYCSVLPGFTFIQHLPLSER 408
Query: 485 VRGPKGPEEKKDCEVVMMIGLPGAGKTTWVTKHAAENPG-KYNILGTNTIMDKMMVAGFK 543
+RG GP+ K +CE++MM+GLP AGKTTW KHAA NP KYNILGTN IMDKM V G +
Sbjct: 409 IRGTVGPKSKAECEILMMVGLPAAGKTTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLR 468
Query: 544 KQMADTGKLNTLLQRAPQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQRKA 603
+Q G+ + L+Q+A QCL + I+IAARKKRN+ILDQTNV +AQRRKM F GFQRKA
Sbjct: 469 RQRNYAGRWDVLIQQATQCLNRLIQIAARKKRNYILDQTNVYGSAQRRKMRPFEGFQRKA 528
Query: 604 VVVCPKDEDYKQRTQKKAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKEEAQ 663
+V+CP DED K RT K+ + EGKD+P+HAVL+MK NFTLP+V + DE+ ++ELQ+EEA
Sbjct: 529 IVICPTDEDLKDRTIKRTDEEGKDVPDHAVLEMKANFTLPDVGDFLDEVLFIELQREEAD 588
Query: 664 KLLEQYKEESKKALPPEKKQ--NTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNF-- 719
KL+ QY EE +KA PP +K+ N G GGG RGRGG GG F
Sbjct: 589 KLVRQYNEEGRKAGPPPEKRFDNRG----------------GGGFRGRGG----GGGFQR 628
Query: 720 ---RGGAPGNRGGYNRRGNMPQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGM 776
RG GNRGG+ RGGG GG G + R+ G G YS NR G
Sbjct: 629 YENRGPPGGNRGGFQ------NRGGGSGGGGNYRGGFNRS----GGGGYSQ----NRWGN 674
Query: 777 PNRGNYNQNFRGRGN 791
NR N N N RG N
Sbjct: 675 NNRDNNNSNNRGSYN 689
Score = 575 bits (1481), Expect = e-164
Identities = 338/735 (45%), Positives = 433/735 (58%), Gaps = 105/735 (14%)
Query: 122 EEEEAASEDENGDDQGFQEGEDELG------DEEEGAGDENGHGEQQPQPPATQQQQPQQ 175
E +AA E E DD+ + +DE G +E E G G QP PP Q P
Sbjct: 31 ERLQAALEAEEPDDERELDADDEPGRPGHINEEVETEGGSELEGTAQPPPPGLQ---PHA 87
Query: 176 QRGAAKEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGKKKAEGGGGGGRPGAPAAG---- 231
+ G SGP +A+ RQ Q K E G R
Sbjct: 88 EPGGY-------SGPDGHYAMDNI---TRQNQFYDTQVIKQENESGYERRPLEMEQQQAY 137
Query: 232 --DGKTEQKGG---------------DKKRGVKRPR---EDHGRGYFEYIEENKYSRAKS 271
+ KTE K G D+++ R R E+ GRGYFE+ E+ R +S
Sbjct: 138 RPEMKTEMKQGAPTSFLPPEASQLKPDRQQFQSRKRPYEENRGRGYFEHREDR---RGRS 194
Query: 272 PQPPVEEEDEHFDDTVVCLDTYNCDLHFKISRDRLSASSLTMESFAFLWAGGRASYGVSK 331
PQPP EE+++ FDDT+V +DTYNCDLHFK++RDR S LT+E FA+LW+G RASYGV +
Sbjct: 195 PQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFAYLWSGARASYGVRR 254
Query: 332 GKVCFEMKVTEKIPVRHLYTKDIDIHEVRIGWSLTTSGMLLGEEEFSYGYSLKGIKTCNC 391
G+VCFEMK+ E+I V+HL + + D H VRIGWSL + LGEE FSYGY G K+ N
Sbjct: 255 GRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSLDSCSTQLGEEPFSYGYGGTGKKSTNS 314
Query: 392 ETEDYGEKFDENDVITCFANFE-SDEVELSYAKNGQDLGVAFKISKEVLAGRPLFPHVLC 450
E+YG+KF ENDVI CFA+FE ++VELS+ KNG+ +G+AF+I KE L G+ L+PHVL
Sbjct: 315 RFENYGDKFAENDVIGCFADFECGNDVELSFTKNGKWMGIAFRIQKEALGGQALYPHVLV 374
Query: 451 HNCAVEFNFGQKEKPYFPIPEEYTFIQNVPLEDRVRGPKGPEEKKDCEVVMMIGLPGAGK 510
NCAVEFNFGQ+ +PY + +TFIQ++PL +R+RG GP+ K +CE++MM+GLP AGK
Sbjct: 375 KNCAVEFNFGQRAEPYCSVLPGFTFIQHLPLSERIRGTVGPKSKAECEILMMVGLPAAGK 434
Query: 511 TTWVTKHAAENPGK-YNILGTNTIMDKMMVAGFKKQMADTGKLNTLLQRAPQCLGKFIEI 569
TTW KHAA NP K YNILGTN IMDKM V G ++Q G+ + L+Q+A QCL + I+I
Sbjct: 435 TTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLRRQRNYAGRWDVLIQQATQCLNRLIQI 494
Query: 570 AARKKRNFILDQTNVSAAAQRRKMCLFAGFQRKAVVVCPKDEDYKQRTQKKAEVEGKDLP 629
AARKKRN+ILDQTNV +AQRRKM F GFQRKA+V+CP DED K RT K+ + EGKD+P
Sbjct: 495 AARKKRNYILDQTNVYGSAQRRKMRPFEGFQRKAIVICPTDEDLKDRTIKRTDEEGKDVP 554
Query: 630 EHAVLKMKGNFTLPEVAECFDEITYVELQKEEAQKLLEQYKEESKKALPPEKKQNTGSKK 689
+HAVL+MK NFTLP+V + DE+ ++ELQ+EEA KL+ QY EE +KA PP +K+
Sbjct: 555 DHAVLEMKANFTLPDVGDFLDEVLFIELQREEADKLVRQYNEEGRKAGPPPEKRFD---- 610
Query: 690 SNKNKSGKNQFNRGGGHRGRGGFNMRGGNFRGGAPGNRGGYNRRGNMPQRGGGGGGSGGI 749
NRGGG GF RGG GG+ R N RG GG GG
Sbjct: 611 -----------NRGGG-----GFRGRGGG---------GGFQRYEN---RGPPGGNRGG- 641
Query: 750 GYPYPRAPVFPGRGSYSNRGNYNRGGMPNRGNYNQNFRGR------GNNRGYKNQSQ--- 800
+ NRG + GG RG +N++ G GNN N S
Sbjct: 642 ---------------FQNRGGGSGGGGNYRGGFNRSGGGGYSQNRWGNNNRDNNNSNNRG 686
Query: 801 GYNQWQQGQFWGQKP 815
YN+ Q Q Q+P
Sbjct: 687 SYNRAPQQQPPPQQP 701
>gi|118601081 heterogeneous nuclear ribonucleoprotein U-like 2 [Homo
sapiens]
Length = 747
Score = 587 bits (1514), Expect = e-167
Identities = 330/737 (44%), Positives = 456/737 (61%), Gaps = 62/737 (8%)
Query: 6 VNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALD----DEEAGGRPAMEPGNGSLD 61
+ VK+LKV+EL+ EL++R L +GLK +L +RLQ ALD ++EAGG A PG G+
Sbjct: 1 MEVKRLKVTELRSELQRRGLDSRGLKVDLAQRLQEALDAEMLEDEAGGGGA-GPG-GACK 58
Query: 62 LGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGPM 121
SG G GGDEEE+EEEEEE+ + L+ + E AA P
Sbjct: 59 AEPRPVAASGGG------PGGDEEEDEEEEEEDEEALLEDEDEEPPPAQALGQAAQPPPE 112
Query: 122 EEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAAK 181
E AA E D + E G G+E G G++ ++ +P+++ G
Sbjct: 113 PPEAAAMEAAAEPDASEKPAEATAGSGGVNGGEEQGLGKR-------EEDEPEERSG--D 163
Query: 182 EAAGKSSGPTSLFAVTVAPPGARQGQQQAGGKKKAEGGGGGGRPGAPAAGDGKTEQKGGD 241
E G PG + ++Q G PA DG
Sbjct: 164 ETPGSE------------VPGDKAAEEQ--------GDDQDSEKSKPAGSDG-------- 195
Query: 242 KKRGVKRPR---EDHGRGYFEYIEENKYSRAKSPQPPVEE-EDEHFDDTVVCLDTYNCDL 297
++RGVKR R ++HGR Y+E+ EE +SR+KSP PP EE +DE D T+V LDTY DL
Sbjct: 196 ERRGVKRQRDEKDEHGRAYYEFREEAYHSRSKSPLPPEEEAKDEEEDQTLVNLDTYTSDL 255
Query: 298 HFKISRDRLSASSLTMESFAFLWAGGRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIH 357
HF++S+DR L E F LW+G R++YGV+KGKVCFE KVT+ +P++ T ++
Sbjct: 256 HFQVSKDRYGGQPLFSEKFPTLWSGARSTYGVTKGKVCFEAKVTQNLPMKEGCT---EVS 312
Query: 358 EVRIGWSLTTSGMLLGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVITCFANFESDEV 417
+R+GWS+ S LGE+EFSYG+ +G+K N + E++G+ F ENDVI CFANFE++EV
Sbjct: 313 LLRVGWSVDFSRPQLGEDEFSYGFDGRGLKAENGQFEEFGQTFGENDVIGCFANFETEEV 372
Query: 418 ELSYAKNGQDLGVAFKISKEVLAGRPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQ 477
ELS++KNG+DLGVAF ISK+ LA R L PHVLC NC VE NFGQKE+P+FP PEE+ FI
Sbjct: 373 ELSFSKNGEDLGVAFWISKDSLADRALLPHVLCKNCVVELNFGQKEEPFFPPPEEFVFIH 432
Query: 478 NVPLEDRVRGPKGPEEKKDCEVVMMIGLPGAGKTTWVTKHAAENPGK-YNILGTNTIMDK 536
VP+E+RVR P+ ++CEV++M+GLPG+GKT W K+A ENP K YN+LG T++++
Sbjct: 433 AVPVEERVRTAVPPKTIEECEVILMVGLPGSGKTQWALKYAKENPEKRYNVLGAETVLNQ 492
Query: 537 MMVAGFKKQMADTGKLNTLLQRAPQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLF 596
M + G ++ D + L+Q+A QCL K ++IA+R KRNFILDQ NV + QRRK+ LF
Sbjct: 493 MRMKGLEEPEMDPKSRDLLVQQASQCLSKLVQIASRTKRNFILDQCNVYNSGQRRKLLLF 552
Query: 597 AGFQRKAVVVCPKDEDYKQRTQKKAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVE 656
F RK VVV P +ED+K+R + + EVEG D+PE +L+MK NF+LPE + DE+TY E
Sbjct: 553 KTFSRKVVVVVPNEEDWKKRLELRKEVEGDDVPESIMLEMKANFSLPEKCDYMDEVTYGE 612
Query: 657 LQKEEAQKLLEQYKEESKKALPPEKKQNTGSKKSNKNKSGKNQFNRGGGHRG---RGGFN 713
L+KEEAQ ++ +YKEE++K LPP +K+ ++++N+NK + +RG G+ G RG N
Sbjct: 613 LEKEEAQPIVTKYKEEARKLLPPSEKRT--NRRNNRNKRNRQNRSRGQGYVGGQRRGYDN 670
Query: 714 MRGGNFRGGAPGNRGGY 730
G G PGNRGGY
Sbjct: 671 RAYGQQYWGQPGNRGGY 687
>gi|21536320 heterogeneous nuclear ribonucleoprotein U-like 1
isoform d [Homo sapiens]
Length = 756
Score = 584 bits (1505), Expect = e-166
Identities = 304/555 (54%), Positives = 383/555 (69%), Gaps = 47/555 (8%)
Query: 247 KRPREDH-GRGYFEYIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFKISRDR 305
KRP E++ GRGYFE+ E+ R +SPQPP EE+++ FDDT+V +DTYNCDLHFK++RDR
Sbjct: 72 KRPYEENRGRGYFEHREDR---RGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDR 128
Query: 306 LSASSLTMESFAFLWAGGRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVRIGWSL 365
S LT+E FA+LW+G RASYGV +G+VCFEMK+ E+I V+HL + + D H VRIGWSL
Sbjct: 129 SSGYPLTIEGFAYLWSGARASYGVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSL 188
Query: 366 TTSGMLLGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVITCFANFE-SDEVELSYAKN 424
+ LGEE FSYGY G K+ N E+YG+KF ENDVI CFA+FE ++VELS+ KN
Sbjct: 189 DSCSTQLGEEPFSYGYGGTGKKSTNSRFENYGDKFAENDVIGCFADFECGNDVELSFTKN 248
Query: 425 GQDLGVAFKISKEVLAGRPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVPLEDR 484
G+ +G+AF+I KE L G+ L+PHVL NCAVEFNFGQ+ +PY + +TFIQ++PL +R
Sbjct: 249 GKWMGIAFRIQKEALGGQALYPHVLVKNCAVEFNFGQRAEPYCSVLPGFTFIQHLPLSER 308
Query: 485 VRGPKGPEEKKDCEVVMMIGLPGAGKTTWVTKHAAENPGK-YNILGTNTIMDKMMVAGFK 543
+RG GP+ K +CE++MM+GLP AGKTTW KHAA NP K YNILGTN IMDKM V G +
Sbjct: 309 IRGTVGPKSKAECEILMMVGLPAAGKTTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLR 368
Query: 544 KQMADTGKLNTLLQRAPQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQRKA 603
+Q G+ + L+Q+A QCL + I+IAARKKRN+ILDQTNV +AQRRKM F GFQRKA
Sbjct: 369 RQRNYAGRWDVLIQQATQCLNRLIQIAARKKRNYILDQTNVYGSAQRRKMRPFEGFQRKA 428
Query: 604 VVVCPKDEDYKQRTQKKAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKEEAQ 663
+V+CP DED K RT K+ + EGKD+P+HAVL+MK NFTLP+V + DE+ ++ELQ+EEA
Sbjct: 429 IVICPTDEDLKDRTIKRTDEEGKDVPDHAVLEMKANFTLPDVGDFLDEVLFIELQREEAD 488
Query: 664 KLLEQYKEESKKALPPEKKQ--NTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNF-- 719
KL+ QY EE +KA PP +K+ N G GGG RGRGG GG F
Sbjct: 489 KLVRQYNEEGRKAGPPPEKRFDNRG----------------GGGFRGRGG----GGGFQR 528
Query: 720 ---RGGAPGNRGGYNRRGNMPQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGM 776
RG GNRGG+ RGGG GG G + R+ G G YS NR G
Sbjct: 529 YENRGPPGGNRGGFQ------NRGGGSGGGGNYRGGFNRS----GGGGYSQ----NRWGN 574
Query: 777 PNRGNYNQNFRGRGN 791
NR N N N RG N
Sbjct: 575 NNRDNNNSNNRGSYN 589
Score = 30.0 bits (66), Expect = 9.1
Identities = 28/101 (27%), Positives = 38/101 (37%), Gaps = 25/101 (24%)
Query: 200 PPGARQGQQQAGGKKKAEGGGGG-------GRPGAPAAG---DGKTEQKGGDKKRGVKRP 249
PP ++ + GG + GGGGG G PG G G GG+ + G R
Sbjct: 503 PPPEKRFDNRGGGGFRGRGGGGGFQRYENRGPPGGNRGGFQNRGGGSGGGGNYRGGFNR- 561
Query: 250 REDHGRGYFEYIEEN------------KYSRAKSPQPPVEE 278
G GY + N Y+RA QPP ++
Sbjct: 562 --SGGGGYSQNRWGNNNRDNNNSNNRGSYNRAPQQQPPPQQ 600
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 88.6 bits (218), Expect = 2e-17
Identities = 76/253 (30%), Positives = 121/253 (47%), Gaps = 12/253 (4%)
Query: 19 ELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSLDLGGDSAGRSGAGLEQEA 78
E KK + K K E E Q ++EE GR + G ++ GG+ G E+E
Sbjct: 774 ERKKEERAGKEEKGE-EEGDQGEGEEEETEGRGEEKEEGGEVE-GGEVEEGKGEREEEEE 831
Query: 79 AAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGPMEEEEAASEDENGDDQGF 138
G+EEE E EEEE +G+ GEE G G + EE E E+E G+ +G
Sbjct: 832 EGEGEEEEGEGEEEEGEGEEEEGEGK--GEEEGEEGEGEE-EGEEGEGEGEEEEGEGEGE 888
Query: 139 QEGEDELGDEE-EGAGDENGHGE-QQPQPPATQQQQPQQQRGAAKEAAGKSSGPTSLFAV 196
+EGE E +EE EG G+E G GE ++ + +++ ++ G +E G+ G
Sbjct: 889 EEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDG-EGE 947
Query: 197 TVAPPGARQGQQQAG---GKKKAEGGGGGGR-PGAPAAGDGKTEQKGGDKKRGVKRPRED 252
G +G+++ G G+++ EG G G G G+G+ E++ G+++ + E+
Sbjct: 948 GEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEE 1007
Query: 253 HGRGYFEYIEENK 265
G G E EE +
Sbjct: 1008 EGEGEGEEEEEGE 1020
Score = 82.8 bits (203), Expect = 1e-15
Identities = 75/275 (27%), Positives = 116/275 (42%), Gaps = 43/275 (15%)
Query: 43 DDEEAGGRPAMEPGNGSLDLGGDSAGRSGAGLEQEAAAGGDEEEEEE---EEEEEGISAL 99
+ EE G E G + + AG+ G E+E G EEEE E EE+EEG +
Sbjct: 760 EGEEVEGEREKEEGERKKE---ERAGKEEKG-EEEGDQGEGEEEETEGRGEEKEEG-GEV 814
Query: 100 DGDQMELG------EENGAAGAADSGPMEEEEAASEDENGDDQGFQEGEDELGDEE---- 149
+G ++E G EE G + G EEEE E+E G+ +G +EGE+ G+EE
Sbjct: 815 EGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEG 874
Query: 150 ---------EGAGDENGHGEQQPQPPATQQQQPQQQRGAAKEAAGKSSGPTSLFAVTVAP 200
EG G+E G GE + + + ++ + G +E GK
Sbjct: 875 EGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGE--------EEGE 926
Query: 201 PGARQGQQQAGGKKKAEGGGGGGR-----PGAPAAGDGKTEQKG---GDKKRGVKRPRED 252
G +G+++ G + +G G G G G+G+ E++G G++ G E
Sbjct: 927 EGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEG 986
Query: 253 HGRGYFEYIEENKYSRAKSPQPPVEEEDEHFDDTV 287
G G E EE + + E +E + V
Sbjct: 987 EGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEV 1021
Score = 80.9 bits (198), Expect = 5e-15
Identities = 75/269 (27%), Positives = 119/269 (44%), Gaps = 41/269 (15%)
Query: 43 DDEEAGGRPAMEPGNGSLDLG-GDSAGRSGAGLEQEAAAGGDEEEEEEE---EEEEGISA 98
++EE G E G G + G G+ G G E+ G+EE EE E EEEEG
Sbjct: 827 EEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEG--- 883
Query: 99 LDGDQMELGEENGAAGAADSGPMEEEEAASEDENGDDQGFQEGE--DELGDEEEGAGD-E 155
+G+ E GE G + EE E E+E G+ +G +EGE + G+EEEG G+ E
Sbjct: 884 -EGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGE 942
Query: 156 NGHGEQQPQPPATQQQQP--------------QQQRGAAKEAAGKSSGPTSLFAVTVAPP 201
+G GE + + + ++ ++ G +E G+ G
Sbjct: 943 DGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEE--------E 994
Query: 202 GARQGQQQAGGKKKAEGGGGGGRPGAPAA------GDGKTEQKGGDKKRGVKRPREDHGR 255
G +G+++ G+++ EG G G G+G+ E++ G+++ G +R +E G
Sbjct: 995 GEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEE-GEEREKEGEGE 1053
Query: 256 GYFEYIEENKYSRAKSPQPPVEEEDEHFD 284
EE + K Q EEE+E D
Sbjct: 1054 ENRRNREEEEEEEGKY-QETGEEENERQD 1081
Score = 67.8 bits (164), Expect = 4e-11
Identities = 75/301 (24%), Positives = 115/301 (38%), Gaps = 57/301 (18%)
Query: 7 NVKKLKVSELKEELKKRRLSDKGLKAE-LMERLQAALDDEEAGGRPAMEPGN-------- 57
NVK + K E+ L+DK +E + + A D E G E G+
Sbjct: 612 NVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQD 671
Query: 58 -----GSLDLGGDSAGRSGAG----LEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGE 108
G D G R G G E+E D EE+E++E E+ G Q E +
Sbjct: 672 EEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQ------GHQKERNQ 725
Query: 109 ENGAAGAADSGPMEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPAT 168
E G + G EEEE E+E +E+EG G E G GE+
Sbjct: 726 EMEEGGEEEHGEGEEEEGDREEE---------------EEKEGEGKEEGEGEEVEGEREK 770
Query: 169 QQQQPQQQRGAAKEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGKKKAEGG--------- 219
++ + +++ A KE G+ G + + + G++K EGG
Sbjct: 771 EEGERKKEERAGKEEKGEEEGDQG---------EGEEEETEGRGEEKEEGGEVEGGEVEE 821
Query: 220 GGGGRPGAPAAGDGKTEQKGGDKKRGVKRPREDHGRGYFEYIEENKYSRAKSPQPPVEEE 279
G G R G+G+ E+ G+++ G E G+G E E + + EEE
Sbjct: 822 GKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEE 881
Query: 280 D 280
+
Sbjct: 882 E 882
Score = 63.2 bits (152), Expect = 1e-09
Identities = 51/184 (27%), Positives = 78/184 (42%), Gaps = 18/184 (9%)
Query: 43 DDEEAGGRPAMEPGNGSLDLGGDSAGRSGAGL--EQEAAAGGDEEEEEEEEEEEGISALD 100
++EE E G G + G+ G G G E+E G+EEE EEE EEEG
Sbjct: 949 EEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGE---- 1004
Query: 101 GDQMELGEENGAAGAADSGPMEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGE 160
GEE G EEEE E E ++G EGE+E G+EE ++ G GE
Sbjct: 1005 ------GEEEGEGEGE-----EEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGE 1053
Query: 161 QQPQPPATQQQQPQQQRGAAKEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGKKKAEGGG 220
+ + ++++ + + +E + G V+ + G+ + KK
Sbjct: 1054 ENRRNREEEEEEEGKYQETGEEENERQDG-EEYKKVSKIKGSVKYGKHKTYQKKSVTNTQ 1112
Query: 221 GGGR 224
G G+
Sbjct: 1113 GNGK 1116
Score = 42.0 bits (97), Expect = 0.002
Identities = 66/329 (20%), Positives = 123/329 (37%), Gaps = 59/329 (17%)
Query: 7 NVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSLDLGGDS 66
N K LK+S ++++ K++ + + L E D +E M+ G
Sbjct: 511 NEKSLKLSPVQKQKKQQTIGELTQDTALTEND----DSDEYEEMSEMKEGKACKQHVSQG 566
Query: 67 AGRSGAGLEQEAAAGGDEEEEEEEE---EEEGISALDGDQMELGEEN------------- 110
+ EA + +E E EE+ E+ + ++ ++E EEN
Sbjct: 567 IFMTQPATTIEAFSD-EEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEI 625
Query: 111 ----------------GAAGAADSGPMEEEEAASEDENGDDQGFQEGEDELGDEEEGAG- 153
+ G A+ GP + E+ + + +Q+ E E G++++G G
Sbjct: 626 LSDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGE 685
Query: 154 -DENGHGEQQ-------PQPPATQQQQPQQQRGAAKEAAGK-SSGPTSLFAVTVAPPGAR 204
+ G GE++ + +Q+Q ++++G KE + G G R
Sbjct: 686 MERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDR 745
Query: 205 QGQQQAGGKKKAEGGG----------GGGRPGAPAAGDGKTEQKGGDKKRGVKRPREDHG 254
+ +++ G+ K EG G G R AG + ++ GD+ G + E G
Sbjct: 746 EEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRG 805
Query: 255 RGYFE--YIEENKYSRAKSPQPPVEEEDE 281
E +E + K + EEE E
Sbjct: 806 EEKEEGGEVEGGEVEEGKGEREEEEEEGE 834
Score = 32.3 bits (72), Expect = 1.8
Identities = 35/169 (20%), Positives = 62/169 (36%), Gaps = 19/169 (11%)
Query: 658 QKEEAQKLLEQYKEESKKALPPEKKQNTGSKK----SNKNKSGKNQFNRGGGHR----GR 709
++EE +K E +E + + E+++ G +K + K + G+ + ++G G GR
Sbjct: 745 REEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGR 804
Query: 710 GGFNMRGGNFRGG----APGNRGGYNRRGNMPQRGGGGGGSGGIGYPYPRAPVFPGRGSY 765
G GG GG G R G + G G G G G G
Sbjct: 805 GEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEE------EGEGKG 858
Query: 766 SNRGNYNRGGMPNRGNYNQNFRGRGNNRGYKNQSQGYNQWQQGQFWGQK 814
G G + G G + + +G + ++G+ G++
Sbjct: 859 EEEGEEGEGEEEGEEGEGEGEEEEGEGEG-EEEGEGEGEEEEGEGEGEE 906
>gi|4826686 DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 [Homo sapiens]
Length = 740
Score = 87.8 bits (216), Expect = 4e-17
Identities = 57/194 (29%), Positives = 99/194 (51%), Gaps = 27/194 (13%)
Query: 290 LDTYNCDLHFKISRDRLSASSLTMESFAFLWAGGRASYGVSKGKVCFEMKVTEKIPVRHL 349
++ Y+ F I D L S ++ W G RA+ G+ KGK H
Sbjct: 93 MNPYDRGSAFAIGSDGLCCQSREVKE----WHGCRATKGLMKGK--------------HY 134
Query: 350 YTKDIDIHE---VRIGWSLTTSGMLLGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVI 406
Y ++ H+ R+GWS + + LG ++F +G+ G K+ N + ++YGE+F +D I
Sbjct: 135 Y--EVSCHDQGLCRVGWSTMQASLDLGTDKFGFGFGGTGKKSHNKQFDNYGEEFTMHDTI 192
Query: 407 TCFANFESDEVELSYAKNGQDLGVAFKISKEVLAGRPLFPHVLCHNCAVEFNFGQKEKPY 466
C+ + + V+ ++KNG+DLG+AF+I + + LFP + N ++FNFG++E
Sbjct: 193 GCYLDIDKGHVK--FSKNGKDLGLAFEIPPH-MKNQALFPACVLKNAELKFNFGEEEFK- 248
Query: 467 FPIPEEYTFIQNVP 480
FP + + + P
Sbjct: 249 FPPKDGFVALSKAP 262
>gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo
sapiens]
Length = 378
Score = 73.6 bits (179), Expect = 7e-13
Identities = 62/195 (31%), Positives = 77/195 (39%), Gaps = 23/195 (11%)
Query: 649 FDEITYVELQKEEAQKLLEQYKEESKKALPPEKKQNTGSKKSNKNKSGKNQFNRGGGHRG 708
FD+ V+ + + + E KKAL ++ Q+ GS++ SG N RGG G
Sbjct: 174 FDDHDTVDKIVVQKYHTINGHNCEVKKALSKQEMQSAGSQRGRGGGSG-NFMGRGGNFGG 232
Query: 709 RGGFNMRGGNFRGGAPGNRGGYNRRGNMPQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNR 768
GG RGGNF G GG RG+ GG G GG G Y P + RG Y
Sbjct: 233 GGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDGGYNGFGGDGGNYGGGPGYSSRGGYGGG 292
Query: 769 G-----------------NYNRGGMPNRGNY--NQNFRGRGNNRGYKNQSQGYNQWQQGQ 809
G YN GG GNY N+ GN G Q Y + G
Sbjct: 293 GPGYGNQGGGYGGGGGYDGYNEGGNFGGGNYGGGGNYNDFGNYSG--QQQSNYGPMKGGS 350
Query: 810 FWGQKPWSQHYHQGY 824
F G+ S Y GY
Sbjct: 351 FGGRSSGSP-YGGGY 364
Score = 44.7 bits (104), Expect = 4e-04
Identities = 31/91 (34%), Positives = 37/91 (40%), Gaps = 27/91 (29%)
Query: 687 SKKSNKNKSGKNQFNRGGGHRGRGGFN--MRGGNFRGGAPGNRGGYNRRGNM-------- 736
S + G N+GGG+ G GG++ GGNF GG G G YN GN
Sbjct: 284 SSRGGYGGGGPGYGNQGGGYGGGGGYDGYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNY 343
Query: 737 -PQRGGG----------------GGGSGGIG 750
P +GG GGGSGG G
Sbjct: 344 GPMKGGSFGGRSSGSPYGGGYGSGGGSGGYG 374
Score = 34.7 bits (78), Expect = 0.37
Identities = 43/171 (25%), Positives = 56/171 (32%), Gaps = 34/171 (19%)
Query: 56 GNGSLDLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAA-- 113
G G+ GG+ GR G G GG + G + GD G G +
Sbjct: 233 GGGNFGRGGNFGGRGGYG------GGGGGSRGSYGGGDGGYNGFGGDGGNYGGGPGYSSR 286
Query: 114 -GAADSGPMEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQ 172
G GP + G G+ EG + G G G+ N G Q QQ
Sbjct: 287 GGYGGGGPGYGNQGGGYGGGGGYDGYNEGGNFGGGNYGGGGNYNDFGNYSGQ----QQSN 342
Query: 173 PQQQRGAAKEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGKKKAEGGGGGG 223
+G + G+SSG +P G G GGG GG
Sbjct: 343 YGPMKGGS--FGGRSSG---------SPYGGGYG----------SGGGSGG 372
Score = 32.0 bits (71), Expect = 2.4
Identities = 24/86 (27%), Positives = 33/86 (38%), Gaps = 4/86 (4%)
Query: 156 NGHGEQQPQPPATQQQQPQQQRGAAKEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGKKK 215
NGH + + + Q+ Q + +G G F G G+ G +
Sbjct: 192 NGHNCEVKKALSKQEMQSAGSQRGRGGGSGNFMGRGGNFG----GGGGNFGRGGNFGGRG 247
Query: 216 AEGGGGGGRPGAPAAGDGKTEQKGGD 241
GGGGGG G+ GDG GGD
Sbjct: 248 GYGGGGGGSRGSYGGGDGGYNGFGGD 273
>gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b
[Homo sapiens]
Length = 372
Score = 70.5 bits (171), Expect = 6e-12
Identities = 58/165 (35%), Positives = 73/165 (44%), Gaps = 27/165 (16%)
Query: 672 ESKKALPPEKKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNF--RGGAPGNRG- 728
E +KAL ++ + S + ++ SG RGGG G F RGGNF RGG G+RG
Sbjct: 176 EVRKALSKQEMASASSSQRGRSGSGNFGGGRGGGFGGNDNFG-RGGNFSGRGGFGGSRGG 234
Query: 729 --------GYNRRGNMPQRGGGGG---------GSGGIGYPYPRAPVFPGRGSYSNRGNY 771
GYN GN GGGG GSGG GY + + G GSY + N
Sbjct: 235 GGYGGSGDGYNGFGNDGGYGGGGPGYSGGSRGYGSGGQGYG-NQGSGYGGSGSYDSYNNG 293
Query: 772 NRGGMPNRGNYNQNFRGRGNNR---GYKNQSQGYNQWQQGQFWGQ 813
GG G NF G G+ Y NQS + + G F G+
Sbjct: 294 GGGGF--GGGSGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGR 336
Score = 36.6 bits (83), Expect = 0.098
Identities = 25/71 (35%), Positives = 31/71 (43%), Gaps = 9/71 (12%)
Query: 684 NTGSKKSNKNKSGKNQFNRGGGHRGRGGFN--------MRGGNFRGGAPGNRGGYNRRGN 735
N G SG N F GG + G +N M+GGNF G + G GG +
Sbjct: 291 NNGGGGGFGGGSGSN-FGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFA 349
Query: 736 MPQRGGGGGGS 746
P+ GG GGS
Sbjct: 350 KPRNQGGYGGS 360
Score = 34.7 bits (78), Expect = 0.37
Identities = 33/102 (32%), Positives = 43/102 (42%), Gaps = 14/102 (13%)
Query: 683 QNTGSKKSNKNKSGK--NQFNRGGGHRGRGGFNMRGGNFRGGAPGNR-GGYNRRGNM--P 737
Q G++ S SG + N GGG G G G NF GG N G YN + + P
Sbjct: 272 QGYGNQGSGYGGSGSYDSYNNGGGGGFGGGS----GSNFGGGGSYNDFGNYNNQSSNFGP 327
Query: 738 QRGGGGGGS-----GGIGYPYPRAPVFPGRGSYSNRGNYNRG 774
+GG GG GG G + + G G S+ +Y G
Sbjct: 328 MKGGNFGGRSSGPYGGGGQYFAKPRNQGGYGGSSSSSSYGSG 369
>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
[Homo sapiens]
Length = 526
Score = 65.9 bits (159), Expect = 2e-10
Identities = 62/223 (27%), Positives = 89/223 (39%), Gaps = 44/223 (19%)
Query: 615 QRTQKKAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKEEAQKLLEQYKEESK 674
Q ++ +E + D V + N T+ VA+ F +I ++ K+ Q ++ Y +
Sbjct: 271 QGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRET 330
Query: 675 KAL----------PP---------EKKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMR 715
L PP + K+ +G+ + + FNRGGG+ GRGG
Sbjct: 331 GKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGN-GRGGRGRG 389
Query: 716 GGNFRGGAPGNRGGYNRRGNMPQRGGGGGG---SGGIGYPYPRA---------------- 756
G RGG G G RG P GGGGGG +G P P
Sbjct: 390 GPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKA 449
Query: 757 --PVFPGRGSYSNR--GNYNRGGMPNRGNYNQ-NFRGRGNNRG 794
P PG G + GNY RG Y++ +RGRG +RG
Sbjct: 450 PKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRG 492
Score = 51.2 bits (121), Expect = 4e-06
Identities = 39/109 (35%), Positives = 52/109 (47%), Gaps = 21/109 (19%)
Query: 696 GKNQFNRGGGHRGRGGFNMRGGNFRGGAPGNRGGYNRRGNMPQRGGGGGGSGGIGYPYPR 755
G Q +RGG RGRGG GG GG + GGY RG RGGG GG GG+G
Sbjct: 207 GYGQQDRGG--RGRGGSGGGGGGGGGGYNRSSGGYEPRG----RGGGRGGRGGMG----- 255
Query: 756 APVFPGRGSYSNRGNYNR-GGMPNRGNYNQNFRGRGNNRGYKNQSQGYN 803
S+RG +N+ GG ++G+ + + + +N Q G N
Sbjct: 256 ---------GSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGEN 295
Score = 50.8 bits (120), Expect = 5e-06
Identities = 43/140 (30%), Positives = 56/140 (40%), Gaps = 15/140 (10%)
Query: 681 KKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNF------RGGAPGNRGGYNRRG 734
++Q+ G ++S G Q N+ G GG GGN+ G+ GGY G
Sbjct: 139 QQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGY---G 195
Query: 735 NMPQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRGNYNQNFRGRGNNRG 794
N Q GGGG G G R G G G YNR G Y RGRG RG
Sbjct: 196 NQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSS----GGYEP--RGRGGGRG 249
Query: 795 YKNQSQGYNQWQQGQFWGQK 814
+ G ++ +F G +
Sbjct: 250 GRGGMGGSDRGGFNKFGGPR 269
Score = 50.4 bits (119), Expect = 7e-06
Identities = 39/131 (29%), Positives = 57/131 (43%), Gaps = 12/131 (9%)
Query: 683 QNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNFRGGAPGNR--------GGYNR-- 732
Q G + + SG GGG+ G+ +M G GG GN+ GGY +
Sbjct: 153 QGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQD 212
Query: 733 RGNMPQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRGNYNQNFRGRGNN 792
RG + G GGGG GG G + + RG RG G +RG +N+ G +
Sbjct: 213 RGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNK--FGGPRD 270
Query: 793 RGYKNQSQGYN 803
+G ++ S+ N
Sbjct: 271 QGSRHDSEQDN 281
Score = 47.0 bits (110), Expect = 7e-05
Identities = 37/108 (34%), Positives = 48/108 (44%), Gaps = 27/108 (25%)
Query: 691 NKNKSGKNQFNR------GGGHRGRGGFNMRGGNFRGGAPGNRGGYNR---RGNMPQRGG 741
N N S +N+ N+ G G GG +M GGN+ G RGGY+R RG RGG
Sbjct: 435 NMNFSWRNECNQCKAPKPDGPGGGPGGSHM-GGNYGDDRRGGRGGYDRGGYRGRGGDRGG 493
Query: 742 GGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRGNYNQNFRGR 789
GG GG +RG + G M +RG + Q+ R R
Sbjct: 494 FRGGRGG-----------------GDRGGFGPGKMDSRGEHRQDRRER 524
Score = 46.6 bits (109), Expect = 9e-05
Identities = 40/143 (27%), Positives = 51/143 (35%), Gaps = 14/143 (9%)
Query: 679 PEKKQNTGSKKSNKNKSGKNQFNRGGGHR--GRGGFNMRGGNFRGGAPGNRGGYNRRGNM 736
P +GS S+ S Q G + GG G + P G + N
Sbjct: 104 PAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNS 163
Query: 737 PQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRGNYNQNFR--------- 787
GGGGGG GG Y ++ + G GS GN ++ G G Y Q R
Sbjct: 164 SS-GGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSG 222
Query: 788 --GRGNNRGYKNQSQGYNQWQQG 808
G G GY S GY +G
Sbjct: 223 GGGGGGGGGYNRSSGGYEPRGRG 245
Score = 46.2 bits (108), Expect = 1e-04
Identities = 42/203 (20%), Positives = 68/203 (33%), Gaps = 16/203 (7%)
Query: 49 GRPAMEPGNGSLDLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGE 108
G+ + PG G ++G G+ Q ++ G + ++ G G Q G+
Sbjct: 92 GQQSSYPGYGQQPAPSSTSGSYGSS-SQSSSYGQPQSGSYSQQPSYG-----GQQQSYGQ 145
Query: 109 ENGAAGAADSGPMEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPAT 168
+ G + ++S G G G+D+ G G G+G Q
Sbjct: 146 QQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQ-SSMSSGGGSGGGYGNQDQSGGGG 204
Query: 169 QQQQPQQQRGAAKEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGKKKAEGGGGGGRPGAP 228
QQ RG G G + G + + GGG GGR G
Sbjct: 205 SGGYGQQDRGGRGRGGSGGGGGGG---------GGGYNRSSGGYEPRGRGGGRGGRGGMG 255
Query: 229 AAGDGKTEQKGGDKKRGVKRPRE 251
+ G + GG + +G + E
Sbjct: 256 GSDRGGFNKFGGPRDQGSRHDSE 278
Score = 37.4 bits (85), Expect = 0.057
Identities = 35/160 (21%), Positives = 60/160 (37%), Gaps = 19/160 (11%)
Query: 128 SEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAAKEAAGKS 187
S++ Q +G G ++ +G+Q P QQ P G+ ++ S
Sbjct: 61 SQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSS 120
Query: 188 S-GPTSLFAVTVAPPGARQGQQQAGGKKKA----------------EGGGGGGRPGAPAA 230
S G + + P + GQQQ+ G++++ GGGGGG G
Sbjct: 121 SYGQPQSGSYSQQP--SYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYG 178
Query: 231 GDGKTEQKGGDKKRGVKRPREDHGRGYFEYIEENKYSRAK 270
D + GG G + G G Y ++++ R +
Sbjct: 179 QDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGR 218
Score = 32.3 bits (72), Expect = 1.8
Identities = 62/267 (23%), Positives = 95/267 (35%), Gaps = 48/267 (17%)
Query: 44 DEEAGGRPAMEPGNGSLDLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQ 103
D+ GG G G D GG G SG G GG E G G +
Sbjct: 198 DQSGGGGSG---GYGQQDRGGRGRGGSGGG---GGGGGGGYNRSSGGYEPRGRGGGRGGR 251
Query: 104 MELGEE-----NGAAGAADSGPMEEEEAASEDEN-------GDDQGFQEGED---ELG-- 146
+G N G D G + E + D N G++ + D ++G
Sbjct: 252 GGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGII 311
Query: 147 --DEEEGAGDENGHGEQQP---QPPATQQ-QQPQQQRGAAKEAAGK--SSGPTSLFAVTV 198
+++ G N + +++ + AT P + A GK S P + T
Sbjct: 312 KTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATR 371
Query: 199 APPGARQGQQQAGGKKKAE----------GGGGGGRPGAPA-AGDGKTEQKGGDKKRGVK 247
R G GG+ + G GGGGR G P+ G G +Q+ GD K
Sbjct: 372 RADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWK--CP 429
Query: 248 RPREDHGRGYFEYIEENKYSRAKSPQP 274
P ++ + N+ ++ K+P+P
Sbjct: 430 NPTCEN----MNFSWRNECNQCKAPKP 452
>gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isoform
B1 [Homo sapiens]
Length = 353
Score = 65.1 bits (157), Expect = 3e-10
Identities = 56/183 (30%), Positives = 72/183 (39%), Gaps = 17/183 (9%)
Query: 650 DEITYVELQKEEAQKLLEQYKEESKKALPPEKKQNTGSKKSNKNKS-GKNQFNRGGGHRG 708
D + + LQK + + E +KAL ++ Q S +S + + G GGG+ G
Sbjct: 164 DPVDKIVLQKYHT---INGHNAEVRKALSRQEMQEVQSSRSGRGGNFGFGDSRGGGGNFG 220
Query: 709 RGGFNMRGGNFRGGAPG---NRG---GYNRRGNMPQRGGGGGGSGGIGYPYPRAPVFPGR 762
G G NFRGG+ G RG GYN G P GGG G GY R G
Sbjct: 221 PGP----GSNFRGGSDGYGSGRGFGDGYNGYGGGP---GGGNFGGSPGYGGGRGGYGGGG 273
Query: 763 GSYSNRGNYNRGGMPNRGNYNQNFRGRGNNRGYKNQSQGYNQWQQGQFWGQKPWSQHYHQ 822
Y N+G GG N G N + Y Q Y + G F G + Y
Sbjct: 274 PGYGNQGGGYGGGYDNYGGGNYGSGNYNDFGNYNQQPSNYGPMKSGNFGGSRNMGGPYGG 333
Query: 823 GYY 825
G Y
Sbjct: 334 GNY 336
Score = 47.8 bits (112), Expect = 4e-05
Identities = 32/99 (32%), Positives = 44/99 (44%), Gaps = 10/99 (10%)
Query: 686 GSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNFRGGAPGNRGGYNRRGNM--PQRGGGG 743
G + G N+GGG+ G G N GGN+ G + G YN++ + P + G
Sbjct: 263 GGGRGGYGGGGPGYGNQGGGYGG-GYDNYGGGNYGSGNYNDFGNYNQQPSNYGPMKSGNF 321
Query: 744 GGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRGNY 782
GGS +G PY G G+Y G+ GG R Y
Sbjct: 322 GGSRNMGGPY-------GGGNYGPGGSGGSGGYGGRSRY 353
>gi|4504447 heterogeneous nuclear ribonucleoprotein A2/B1 isoform A2
[Homo sapiens]
Length = 341
Score = 65.1 bits (157), Expect = 3e-10
Identities = 56/183 (30%), Positives = 72/183 (39%), Gaps = 17/183 (9%)
Query: 650 DEITYVELQKEEAQKLLEQYKEESKKALPPEKKQNTGSKKSNKNKS-GKNQFNRGGGHRG 708
D + + LQK + + E +KAL ++ Q S +S + + G GGG+ G
Sbjct: 152 DPVDKIVLQKYHT---INGHNAEVRKALSRQEMQEVQSSRSGRGGNFGFGDSRGGGGNFG 208
Query: 709 RGGFNMRGGNFRGGAPG---NRG---GYNRRGNMPQRGGGGGGSGGIGYPYPRAPVFPGR 762
G G NFRGG+ G RG GYN G P GGG G GY R G
Sbjct: 209 PGP----GSNFRGGSDGYGSGRGFGDGYNGYGGGP---GGGNFGGSPGYGGGRGGYGGGG 261
Query: 763 GSYSNRGNYNRGGMPNRGNYNQNFRGRGNNRGYKNQSQGYNQWQQGQFWGQKPWSQHYHQ 822
Y N+G GG N G N + Y Q Y + G F G + Y
Sbjct: 262 PGYGNQGGGYGGGYDNYGGGNYGSGNYNDFGNYNQQPSNYGPMKSGNFGGSRNMGGPYGG 321
Query: 823 GYY 825
G Y
Sbjct: 322 GNY 324
Score = 47.8 bits (112), Expect = 4e-05
Identities = 32/99 (32%), Positives = 44/99 (44%), Gaps = 10/99 (10%)
Query: 686 GSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNFRGGAPGNRGGYNRRGNM--PQRGGGG 743
G + G N+GGG+ G G N GGN+ G + G YN++ + P + G
Sbjct: 251 GGGRGGYGGGGPGYGNQGGGYGG-GYDNYGGGNYGSGNYNDFGNYNQQPSNYGPMKSGNF 309
Query: 744 GGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRGNY 782
GGS +G PY G G+Y G+ GG R Y
Sbjct: 310 GGSRNMGGPY-------GGGNYGPGGSGGSGGYGGRSRY 341
>gi|109452587 family with sequence similarity 98, member B isoform 1
[Homo sapiens]
Length = 433
Score = 63.9 bits (154), Expect = 6e-10
Identities = 43/104 (41%), Positives = 47/104 (45%), Gaps = 3/104 (2%)
Query: 703 GGGHRGRGGFNMRGGNFRGGAPGNRGGYNRRGNMPQRGGGGGGSGGIGYPYPRAPVFPGR 762
GGG G GG GG GG G RGG+ G GGGGGG G G R F GR
Sbjct: 332 GGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGG-FQGR 390
Query: 763 GSYSNRGNY-NRGGMPNRGNYNQNFRGRGNNRGYKNQSQGYNQW 805
G Y RG Y RGG RG Y + G G G GY ++
Sbjct: 391 GDYGGRGGYGGRGGYGGRG-YGDPYGGGGGGGGGGGGGGGYRRY 433
Score = 36.6 bits (83), Expect = 0.098
Identities = 31/99 (31%), Positives = 38/99 (38%), Gaps = 3/99 (3%)
Query: 160 EQQPQPPATQQQQPQQQRGAAKEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGKKKAEGG 219
E +P PP Q +Q+ G + G G G R G GG GG
Sbjct: 314 EIEPPPPEMPPWQKRQEGGGGRGGWGGGGGGGGRGGG--GGGGGRGGWGGGGGGWGGGGG 371
Query: 220 GGGGRPGAPAAGDGKTEQKGGDKKRGVKRPREDH-GRGY 257
GGGG G G G + +G RG R + GRGY
Sbjct: 372 GGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGY 410
>gi|12056465 fibrillarin [Homo sapiens]
Length = 321
Score = 58.5 bits (140), Expect = 2e-08
Identities = 39/84 (46%), Positives = 41/84 (48%), Gaps = 15/84 (17%)
Query: 702 RGGGHRGRGGFNMRGGNFRGGAPGNRGGYNRRGNMPQRG----GGGGGSGGIGYPYPRAP 757
RGGG GRGGF RGG RGG G GG R G RG GGGGG GG G
Sbjct: 8 RGGGFGGRGGFGDRGG--RGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGG------- 58
Query: 758 VFPGRGSYSNRGNYNRGGMPNRGN 781
G G + + GN RG RGN
Sbjct: 59 --RGGGGFHSGGNRGRGRGGKRGN 80
Score = 49.3 bits (116), Expect = 1e-05
Identities = 45/107 (42%), Positives = 48/107 (44%), Gaps = 41/107 (38%)
Query: 696 GKNQFNRGGGHRGRGGFNM---RGGNFRGGAPGNRGGYNRRGNMPQRGGGGGGSGGIGYP 752
G+ F GG GRGGF RGG FRG RG RGGGGGG GG G
Sbjct: 14 GRGGFGDRGGRGGRGGFGGGRGRGGGFRG-----RG----------RGGGGGGGGGGG-- 56
Query: 753 YPRAPVFPGRGSYSNRGNYNRGGMPNRGNYNQNFRGRGNNRGYKNQS 799
GRG G ++ GG NRG RGRG RG NQS
Sbjct: 57 -------GGRGG----GGFHSGG--NRG------RGRGGKRG--NQS 82
Score = 32.7 bits (73), Expect = 1.4
Identities = 23/62 (37%), Positives = 28/62 (45%), Gaps = 1/62 (1%)
Query: 702 RGGGHRGRGGFNMRGGNFRGGAPGNRGGYNRRGNMPQRGGGGGGSGGIGYPYPRAPVFPG 761
RG G G GG GG RGG + GG RG +RG G + + P+ VF
Sbjct: 41 RGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGRGRGGKRGNQSGKNVMV-EPHRHEGVFIC 99
Query: 762 RG 763
RG
Sbjct: 100 RG 101
>gi|4504445 heterogeneous nuclear ribonucleoprotein A1 isoform a
[Homo sapiens]
Length = 320
Score = 58.2 bits (139), Expect = 3e-08
Identities = 44/122 (36%), Positives = 55/122 (45%), Gaps = 13/122 (10%)
Query: 672 ESKKALPPEKKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNFRGGAPGNRGGYN 731
E +KAL ++ + S + ++ SG RGGG G F RGGNF G RGG+
Sbjct: 176 EVRKALSKQEMASASSSQRGRSGSGNFGGGRGGGFGGNDNFG-RGGNFSG-----RGGFG 229
Query: 732 RRGNMPQRGGGGGGSGGIGYP--YPRAPVFPGRGSYSNRGNYNRGGMPNRGNYNQNFRGR 789
RGGGG G G GY F G GSY++ GNYN NF GR
Sbjct: 230 -----GSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGR 284
Query: 790 GN 791
+
Sbjct: 285 SS 286
Score = 37.4 bits (85), Expect = 0.057
Identities = 33/97 (34%), Positives = 42/97 (43%), Gaps = 15/97 (15%)
Query: 693 NKSGKNQF--NRGGGH-----RGRGGFNMRGGNFRGGAPGNR-GGYNRRGNM--PQRGGG 742
N SG+ F +RGGG G GF G NF GG N G YN + + P +GG
Sbjct: 221 NFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGN 280
Query: 743 GGGS-----GGIGYPYPRAPVFPGRGSYSNRGNYNRG 774
GG GG G + + G G S+ +Y G
Sbjct: 281 FGGRSSGPYGGGGQYFAKPRNQGGYGGSSSSSSYGSG 317
>gi|166795264 AE binding protein 2 isoform b [Homo sapiens]
Length = 517
Score = 57.8 bits (138), Expect = 4e-08
Identities = 47/197 (23%), Positives = 74/197 (37%), Gaps = 16/197 (8%)
Query: 43 DDEEAGGRPAMEPGNGSLDLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGD 102
D EE + PG+ SA R A +E +EEEE E E + G
Sbjct: 10 DLEELSRLSPLPPGSPG------SAARGRAEPPEEEEEEEEEEEEAEAEAVAALLLNGGS 63
Query: 103 QMELGEENGAAGAADSGPMEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQ 162
G G G ++ M E S + G+D+ +E ++E DE +G +
Sbjct: 64 GGGGGGGGGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAE 123
Query: 163 PQPPATQQQQPQQQRGAAKEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGKKKAEGGGGG 222
++ + R + AA SSG ++G ++ G + ++GGGGG
Sbjct: 124 SLVGSSGGSSSDETRSLSPGAASSSSGDGD----------GKEGLEEPKGPRGSQGGGGG 173
Query: 223 GRPGAPAAGDGKTEQKG 239
G + G E G
Sbjct: 174 GSSSSSVVSSGGDEGYG 190
Score = 35.8 bits (81), Expect = 0.17
Identities = 29/141 (20%), Positives = 57/141 (40%), Gaps = 1/141 (0%)
Query: 14 SELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSLDLGGDSAGRSGAG 73
+E EE ++ ++ +AE + L GG G G + + + S +
Sbjct: 33 AEPPEEEEEEEEEEEEAEAEAVAALLLNGGSGGGGGGGGGGVGGGEAETMSEPSPESASQ 92
Query: 74 LEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGPMEEEEAASEDENG 133
++ D+EEEE+E G + L +G + + ++ + A+S +G
Sbjct: 93 AGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDETRSLSPGAASSSSGDG 152
Query: 134 D-DQGFQEGEDELGDEEEGAG 153
D +G +E + G + G G
Sbjct: 153 DGKEGLEEPKGPRGSQGGGGG 173
>gi|166795262 AE binding protein 2 isoform a [Homo sapiens]
Length = 503
Score = 57.8 bits (138), Expect = 4e-08
Identities = 47/197 (23%), Positives = 74/197 (37%), Gaps = 16/197 (8%)
Query: 43 DDEEAGGRPAMEPGNGSLDLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGD 102
D EE + PG+ SA R A +E +EEEE E E + G
Sbjct: 10 DLEELSRLSPLPPGSPG------SAARGRAEPPEEEEEEEEEEEEAEAEAVAALLLNGGS 63
Query: 103 QMELGEENGAAGAADSGPMEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQ 162
G G G ++ M E S + G+D+ +E ++E DE +G +
Sbjct: 64 GGGGGGGGGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAE 123
Query: 163 PQPPATQQQQPQQQRGAAKEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGKKKAEGGGGG 222
++ + R + AA SSG ++G ++ G + ++GGGGG
Sbjct: 124 SLVGSSGGSSSDETRSLSPGAASSSSGDGD----------GKEGLEEPKGPRGSQGGGGG 173
Query: 223 GRPGAPAAGDGKTEQKG 239
G + G E G
Sbjct: 174 GSSSSSVVSSGGDEGYG 190
Score = 35.8 bits (81), Expect = 0.17
Identities = 29/141 (20%), Positives = 57/141 (40%), Gaps = 1/141 (0%)
Query: 14 SELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSLDLGGDSAGRSGAG 73
+E EE ++ ++ +AE + L GG G G + + + S +
Sbjct: 33 AEPPEEEEEEEEEEEEAEAEAVAALLLNGGSGGGGGGGGGGVGGGEAETMSEPSPESASQ 92
Query: 74 LEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGPMEEEEAASEDENG 133
++ D+EEEE+E G + L +G + + ++ + A+S +G
Sbjct: 93 AGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDETRSLSPGAASSSSGDG 152
Query: 134 D-DQGFQEGEDELGDEEEGAG 153
D +G +E + G + G G
Sbjct: 153 DGKEGLEEPKGPRGSQGGGGG 173
>gi|56699482 hypothetical protein LOC25940 [Homo sapiens]
Length = 518
Score = 56.2 bits (134), Expect = 1e-07
Identities = 60/182 (32%), Positives = 77/182 (42%), Gaps = 44/182 (24%)
Query: 677 LPPEKKQNTGSKKSNKNKSGKNQFNRGG-GHRGRGGFNMRGGNFRGGAPGNRGGYNR--- 732
+PP +K+ G ++ + G RGG H GG RGG+ +GG G RGGY+
Sbjct: 319 MPPWQKRQDGPQQQTGGRGG----GRGGYEHSSYGG---RGGHEQGGGRGGRGGYDHGGR 371
Query: 733 ---RGNMPQRGGGGGGSGGIG----YPYPRAPVFPG--RGSYSNRGNYNRGGMP------ 777
RGN Q G GGSGG G Y + PG G +S+ G Y GG
Sbjct: 372 GGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSS-GGYQGGGYGGFQTSS 430
Query: 778 -------NRGNYNQNFR--------GRGNNRGYKNQSQGY-NQWQQGQFWGQKPWSQHYH 821
G Y Q+ R RG RG + G + QG WG + SQ+YH
Sbjct: 431 SYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGR-GSQNYH 489
Query: 822 QG 823
QG
Sbjct: 490 QG 491
Score = 48.5 bits (114), Expect = 2e-05
Identities = 39/123 (31%), Positives = 54/123 (43%), Gaps = 11/123 (8%)
Query: 683 QNTGSKKSNKNKSGKNQFNRGGGHRGRG--GF----NMRGGNFRGGAPGNRGGYNRRGNM 736
Q+ G + S G + + GG++G G GF + G ++GG Y G+
Sbjct: 395 QDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHH 454
Query: 737 PQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNR----GNYNQNFRGRGNN 792
RGGG GG GG G RA G G ++ NY++GG + G Y N G G
Sbjct: 455 GDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQ-NYHQGGQFEQHFQHGGYQYNHSGFGQG 513
Query: 793 RGY 795
R Y
Sbjct: 514 RHY 516
Score = 40.8 bits (94), Expect = 0.005
Identities = 35/110 (31%), Positives = 45/110 (40%), Gaps = 12/110 (10%)
Query: 721 GGAPGNRGGYNR-----RGNMPQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGG 775
GG G RGGY RG Q GGG GG GG Y GRG+ ++G + GG
Sbjct: 334 GGRGGGRGGYEHSSYGGRGGHEQ-GGGRGGRGG----YDHGGRGGGRGN-KHQGGWTDGG 387
Query: 776 MPNRGNYNQ-NFRGRGNNRGYKNQSQGYNQWQQGQFWGQKPWSQHYHQGY 824
G Y +R G G + +Q G + G + S + GY
Sbjct: 388 SGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGY 437
Score = 33.1 bits (74), Expect = 1.1
Identities = 45/176 (25%), Positives = 60/176 (34%), Gaps = 23/176 (13%)
Query: 100 DGDQMELGEENGAAGAADSGPM-----EEEEAASEDENGDDQGFQEGEDELGDEEEGA-- 152
DG Q + G G G + E+ G D G + G G++ +G
Sbjct: 327 DGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGR--GNKHQGGWT 384
Query: 153 -GDENGHGEQQPQPPATQQQQPQQQRGAAKEAAGKSSGPTSLFAVTVAPPGA-------- 203
G G G Q QP G + G G F + + G+
Sbjct: 385 DGGSGGGGGYQDGGYRDSGFQPGGYHGG-HSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQ 443
Query: 204 RQGQQQAGGKKKAEGGGGGGRPGAPAAGDGKTEQKGGDKKRGVKRPREDHGRGYFE 259
+ + Q GG GGG GGR G G G+ Q GG RG + H G FE
Sbjct: 444 QDNRYQDGGHHGDRGGGRGGRGGRGGRG-GRAGQGGGWGGRG---SQNYHQGGQFE 495
Score = 32.7 bits (73), Expect = 1.4
Identities = 29/97 (29%), Positives = 38/97 (39%), Gaps = 15/97 (15%)
Query: 145 LGDEEEGAGDENGHGEQQPQPPATQQQQ--PQQQRGAAKEAAGKSSGPTSLFAVTVAPPG 202
+G + G N P+ P Q++Q PQQQ G G+ S + G
Sbjct: 299 MGRVPDRGGRPNEIEPPPPEMPPWQKRQDGPQQQTGG--RGGGRGGYEHSSY-------G 349
Query: 203 ARQGQQQAGGKKKAEGGGGGGRPGAPAAGDGKTEQKG 239
R G +Q GG+ GG GG G G G Q G
Sbjct: 350 GRGGHEQGGGR----GGRGGYDHGGRGGGRGNKHQGG 382
Score = 31.2 bits (69), Expect = 4.1
Identities = 22/58 (37%), Positives = 27/58 (46%), Gaps = 7/58 (12%)
Query: 200 PPGARQGQQQAGGKKKAEGGGGGGRPG---APAAGDGKTEQKGGDKKRGVKRPREDHG 254
PP Q++ G ++ GG GGGR G + G G EQ GG RG DHG
Sbjct: 316 PPEMPPWQKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRG----GYDHG 369
>gi|21735415 centromere protein B [Homo sapiens]
Length = 599
Score = 55.8 bits (133), Expect = 2e-07
Identities = 40/130 (30%), Positives = 57/130 (43%), Gaps = 10/130 (7%)
Query: 43 DDEEAGGRPAMEPGNGSLDLGGDSAGRSGAGLEQEAAAGGD-----EEEEEEEEEEEGIS 97
++EE G E G + GG+ G E+E GD EEEE+EE EG+
Sbjct: 416 EEEEGEGEEEEEEGEEEEEEGGEG---EELGEEEEVEEEGDVDSDEEEEEDEESSSEGLE 472
Query: 98 ALDGDQ--MELGEENGAAGAADSGPMEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDE 155
A D Q +E G GA GA + E+ D +E ++E DE+E D+
Sbjct: 473 AEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDD 532
Query: 156 NGHGEQQPQP 165
G++ P P
Sbjct: 533 EEDGDEVPVP 542
Score = 47.8 bits (112), Expect = 4e-05
Identities = 30/88 (34%), Positives = 41/88 (46%), Gaps = 9/88 (10%)
Query: 83 DEEEEEEEEEEEGISALDGDQMELGEENGAAG--------AADSGPMEEEEAASEDENGD 134
+EEEEEEEEEEEG + ++ E EE G G + G ++ +E EDE
Sbjct: 408 EEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESS 467
Query: 135 DQGFQEGEDELGDEEEGAGDENGHGEQQ 162
+G E ED E G +G Q+
Sbjct: 468 SEGL-EAEDWAQGVVEAGGSFGAYGAQE 494
Score = 46.2 bits (108), Expect = 1e-04
Identities = 30/89 (33%), Positives = 41/89 (46%), Gaps = 13/89 (14%)
Query: 68 GRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGPMEEEEAA 127
G A + + G+EEEEEEEEEEE EE + G EEEE
Sbjct: 391 GGPNATITTSLKSEGEEEEEEEEEEEE-------------EEGEGEEEEEEGEEEEEEGG 437
Query: 128 SEDENGDDQGFQEGEDELGDEEEGAGDEN 156
+E G+++ +E D DEEE +E+
Sbjct: 438 EGEELGEEEEVEEEGDVDSDEEEEEDEES 466
Score = 32.3 bits (72), Expect = 1.8
Identities = 18/50 (36%), Positives = 30/50 (60%), Gaps = 5/50 (10%)
Query: 122 EEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQ 171
EEEE E+E +++G E E+E G+EEE +E G GE+ + +++
Sbjct: 407 EEEEEEEEEE--EEEGEGEEEEEEGEEEE---EEGGEGEELGEEEEVEEE 451
>gi|27894378 chloride intracellular channel 6 [Homo sapiens]
Length = 686
Score = 55.5 bits (132), Expect = 2e-07
Identities = 70/258 (27%), Positives = 99/258 (38%), Gaps = 54/258 (20%)
Query: 45 EEAGGRPAMEPGNGSLDLGG--DSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGD 102
EEA RP + G+ S + G D+ G G +E E AG E E + GD
Sbjct: 139 EEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPAGDSVEAEGRVGDSVDAEGPAGD 198
Query: 103 QME----LGEENGAAG-AADSGPMEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENG 157
++ LG+ A G A DS E S D G + E +GD E AGD G
Sbjct: 199 SVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAGDSVDAEGRVGDSVE-AGDPAG 257
Query: 158 HGEQQPQP-------------------PATQQQ----QPQQQ------------RGAAKE 182
G + P PA + + +PQQ AA E
Sbjct: 258 DGVEAGVPAGDSVEAEGPAGDSMDAEGPAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGE 317
Query: 183 AAGKSSGPTSLFAVTVAP-PGARQGQQQAGGKKKAEGGGGGGRPGAPAAGDGKTEQKGGD 241
+AG+S G + A A PG + ++ A G +A+ G GDG ++ G D
Sbjct: 318 SAGRSPGELAWDAAEEAEVPGVKGSEEAAPGDARADA-------GEDRVGDGPQQEPGED 370
Query: 242 ---KKRGVKRPREDHGRG 256
++R + PRE+ G
Sbjct: 371 EERRERSPEGPREEEAAG 388
Score = 44.3 bits (103), Expect = 5e-04
Identities = 51/194 (26%), Positives = 74/194 (38%), Gaps = 24/194 (12%)
Query: 43 DDEEAGGRPAMEPGNGSLDLGGDSA-GRSGAGLEQEAAAGGDEEEEEEEEEEEGISA--- 98
D EA G P S+D G + R +G Q++ G + E E G SA
Sbjct: 268 DSVEAEG-----PAGDSMDAEGPAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRS 322
Query: 99 ---LDGDQMELGEENGAAGAADSGPMEEEEAASEDENGDDQGFQEGEDELGDEE--EGAG 153
L D E E G G+ ++ P + A ED GD + GEDE E EG
Sbjct: 323 PGELAWDAAEEAEVPGVKGSEEAAPGDARADAGEDRVGDGPQQEPGEDEERRERSPEGPR 382
Query: 154 DENGHGEQQPQPPATQQQQPQQQRGAAKEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGK 213
+E G ++ P ++ + RGAA+ P + + +A G +G +A
Sbjct: 383 EEEAAGGEEESPDSS--PHGEASRGAAE--------PEAQLSNHLAEEGPAEGSGEAARV 432
Query: 214 KKAEGGGGGGRPGA 227
G P A
Sbjct: 433 NGRREDGEASEPRA 446
Score = 43.1 bits (100), Expect = 0.001
Identities = 51/205 (24%), Positives = 71/205 (34%), Gaps = 21/205 (10%)
Query: 46 EAGGRPAMEPGNGSLDLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGD-QM 104
E G P G G + A + G AGG + E E G G+ +
Sbjct: 26 ERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGGPDRGPEAEARGTRGAHGETEA 85
Query: 105 ELGEENGAA---GAADSGPMEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQ 161
E G GA G ++ ++ E AS QG GE + E+ A + EQ
Sbjct: 86 EEGAPEGAEVPQGGEETSGAQQVEGASPGRGA--QGEPRGEAQREPEDSAAPERQEEAEQ 143
Query: 162 QPQPPATQQQQPQQQRGAAKEAAGKS---SGPTSLFAVTVAPPG-ARQGQQQAGGKKKAE 217
+P+ P G+A AG S GP P G + + + + G AE
Sbjct: 144 RPEVP----------EGSASGEAGDSVDAEGPLGDNIEAEGPAGDSVEAEGRVGDSVDAE 193
Query: 218 GGGGGGRPGAPAAGDG-KTEQKGGD 241
G G GD + E GD
Sbjct: 194 GPAGDSVDAEGPLGDNIQAEGPAGD 218
Score = 32.3 bits (72), Expect = 1.8
Identities = 33/126 (26%), Positives = 49/126 (38%), Gaps = 16/126 (12%)
Query: 163 PQPPATQQQQPQQQRGAAKEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGKKKAEGGGGG 222
P+ PA ++P G A G++ GP GA + + A K+A GGG
Sbjct: 18 PEVPAPLAERP----GEPGAAGGEAEGPE-------GSEGAEEAPRGAAAVKEAGGGGPD 66
Query: 223 GRPGAPAAG----DGKTEQKGGDKKRGVKRPREDHGRGYFEYIEENKYSRAKSPQPPVEE 278
P A A G G+TE + G G + P+ + +E R +P E
Sbjct: 67 RGPEAEARGTRGAHGETEAEEG-APEGAEVPQGGEETSGAQQVEGASPGRGAQGEPRGEA 125
Query: 279 EDEHFD 284
+ E D
Sbjct: 126 QREPED 131
>gi|156151396 heterogeneous nuclear ribonucleoprotein R isoform 3
[Homo sapiens]
Length = 535
Score = 55.1 bits (131), Expect = 3e-07
Identities = 58/224 (25%), Positives = 88/224 (39%), Gaps = 63/224 (28%)
Query: 647 ECFDEITYVELQKEEAQKLLEQYKEESKKALPPEKK--QNTGSKKSNKNKSGKNQF---- 700
+ DE+ E++ EE + +L A PP+KK + +++++++ + ++ +
Sbjct: 291 KAMDEMNGKEIEGEEIEIVL---------AKPPDKKRKERQAARQASRSTAYEDYYYHPP 341
Query: 701 ----------NRGGGHRGRG----------------GFNMRGGNFRGGAPGNRGGYNRRG 734
RGGG G G G++ ++RGG GY+
Sbjct: 342 PRMPPPIRGRGRGGGRGGYGYPPDYYGYEDYYDDYYGYDYH--DYRGGYEDPYYGYDDGY 399
Query: 735 NMPQRGGGGGGSG------GIGYPYPR---------APVFPGRGSYSNRGN-----YNRG 774
+ RGGG GG G G G P PR AP+ P RGS RG RG
Sbjct: 400 AVRGRGGGRGGRGAPPPPRGRGAPPPRGRAGYSQRGAPLGPPRGSRGGRGGPAQQQRGRG 459
Query: 775 GMPNRGNYNQNFRGRGNNRGYKNQSQGYNQWQQGQFWGQKPWSQ 818
+RGN N G+ GY Q Q WG +P +Q
Sbjct: 460 SRGSRGNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWGSQPIAQ 503
Score = 44.3 bits (103), Expect = 5e-04
Identities = 48/141 (34%), Positives = 56/141 (39%), Gaps = 41/141 (29%)
Query: 702 RGGGHRGRGGFNMRGGNFRGGAPGNRG--GYNRRGNM--PQRGGGGGGSGGIGYPYPRAP 757
RGGG GRG G GAP RG GY++RG P RG GG G A
Sbjct: 404 RGGGRGGRGAPPPPRGR---GAPPPRGRAGYSQRGAPLGPPRGSRGGRGGP-------AQ 453
Query: 758 VFPGRGSYSNRGNY--NRGGMPNRGNYNQ--NFRGRGNNR-------------------- 793
GRGS +RGN N GG YNQ + R + NN+
Sbjct: 454 QQRGRGSRGSRGNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWGSQPIAQQPLQQGGDYS 513
Query: 794 ---GYKNQSQGYNQWQQGQFW 811
GY N +Q + Q GQ W
Sbjct: 514 GNYGYNNDNQEFYQDTYGQQW 534
Score = 30.4 bits (67), Expect = 7.0
Identities = 36/141 (25%), Positives = 50/141 (35%), Gaps = 28/141 (19%)
Query: 129 EDENGDDQGFQEGEDELGDEEEGAGDENGH----------GEQQPQPPATQQQQPQQQRG 178
ED D G+ + G E+ G ++G+ G P PP + P + R
Sbjct: 370 EDYYDDYYGYDYHDYRGGYEDPYYGYDDGYAVRGRGGGRGGRGAPPPPRGRGAPPPRGR- 428
Query: 179 AAKEAAGKSSGPTSLFAVTVAPPGARQG-----QQQAGGKKKAEGGGGGGRPGAPAAGDG 233
A G GP P G+R G QQQ G + G GG G DG
Sbjct: 429 AGYSQRGAPLGP---------PRGSRGGRGGPAQQQRGRGSRGSRGNRGGNVGGKRKADG 479
Query: 234 KTEQKGGDKKRGVKRPREDHG 254
+ D KR +++ G
Sbjct: 480 YNQP---DSKRRQTNNQQNWG 497
>gi|156151394 heterogeneous nuclear ribonucleoprotein R isoform 1
[Homo sapiens]
Length = 636
Score = 55.1 bits (131), Expect = 3e-07
Identities = 58/224 (25%), Positives = 88/224 (39%), Gaps = 63/224 (28%)
Query: 647 ECFDEITYVELQKEEAQKLLEQYKEESKKALPPEKK--QNTGSKKSNKNKSGKNQF---- 700
+ DE+ E++ EE + +L A PP+KK + +++++++ + ++ +
Sbjct: 392 KAMDEMNGKEIEGEEIEIVL---------AKPPDKKRKERQAARQASRSTAYEDYYYHPP 442
Query: 701 ----------NRGGGHRGRG----------------GFNMRGGNFRGGAPGNRGGYNRRG 734
RGGG G G G++ ++RGG GY+
Sbjct: 443 PRMPPPIRGRGRGGGRGGYGYPPDYYGYEDYYDDYYGYDYH--DYRGGYEDPYYGYDDGY 500
Query: 735 NMPQRGGGGGGSG------GIGYPYPR---------APVFPGRGSYSNRGN-----YNRG 774
+ RGGG GG G G G P PR AP+ P RGS RG RG
Sbjct: 501 AVRGRGGGRGGRGAPPPPRGRGAPPPRGRAGYSQRGAPLGPPRGSRGGRGGPAQQQRGRG 560
Query: 775 GMPNRGNYNQNFRGRGNNRGYKNQSQGYNQWQQGQFWGQKPWSQ 818
+RGN N G+ GY Q Q WG +P +Q
Sbjct: 561 SRGSRGNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWGSQPIAQ 604
Score = 44.3 bits (103), Expect = 5e-04
Identities = 48/141 (34%), Positives = 56/141 (39%), Gaps = 41/141 (29%)
Query: 702 RGGGHRGRGGFNMRGGNFRGGAPGNRG--GYNRRGNM--PQRGGGGGGSGGIGYPYPRAP 757
RGGG GRG G GAP RG GY++RG P RG GG G A
Sbjct: 505 RGGGRGGRGAPPPPRGR---GAPPPRGRAGYSQRGAPLGPPRGSRGGRGGP-------AQ 554
Query: 758 VFPGRGSYSNRGNY--NRGGMPNRGNYNQ--NFRGRGNNR-------------------- 793
GRGS +RGN N GG YNQ + R + NN+
Sbjct: 555 QQRGRGSRGSRGNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWGSQPIAQQPLQQGGDYS 614
Query: 794 ---GYKNQSQGYNQWQQGQFW 811
GY N +Q + Q GQ W
Sbjct: 615 GNYGYNNDNQEFYQDTYGQQW 635
Score = 30.4 bits (67), Expect = 7.0
Identities = 36/141 (25%), Positives = 50/141 (35%), Gaps = 28/141 (19%)
Query: 129 EDENGDDQGFQEGEDELGDEEEGAGDENGH----------GEQQPQPPATQQQQPQQQRG 178
ED D G+ + G E+ G ++G+ G P PP + P + R
Sbjct: 471 EDYYDDYYGYDYHDYRGGYEDPYYGYDDGYAVRGRGGGRGGRGAPPPPRGRGAPPPRGR- 529
Query: 179 AAKEAAGKSSGPTSLFAVTVAPPGARQG-----QQQAGGKKKAEGGGGGGRPGAPAAGDG 233
A G GP P G+R G QQQ G + G GG G DG
Sbjct: 530 AGYSQRGAPLGP---------PRGSRGGRGGPAQQQRGRGSRGSRGNRGGNVGGKRKADG 580
Query: 234 KTEQKGGDKKRGVKRPREDHG 254
+ D KR +++ G
Sbjct: 581 YNQP---DSKRRQTNNQQNWG 598
>gi|156151392 heterogeneous nuclear ribonucleoprotein R isoform 4
[Homo sapiens]
Length = 532
Score = 55.1 bits (131), Expect = 3e-07
Identities = 58/224 (25%), Positives = 88/224 (39%), Gaps = 63/224 (28%)
Query: 647 ECFDEITYVELQKEEAQKLLEQYKEESKKALPPEKK--QNTGSKKSNKNKSGKNQF---- 700
+ DE+ E++ EE + +L A PP+KK + +++++++ + ++ +
Sbjct: 288 KAMDEMNGKEIEGEEIEIVL---------AKPPDKKRKERQAARQASRSTAYEDYYYHPP 338
Query: 701 ----------NRGGGHRGRG----------------GFNMRGGNFRGGAPGNRGGYNRRG 734
RGGG G G G++ ++RGG GY+
Sbjct: 339 PRMPPPIRGRGRGGGRGGYGYPPDYYGYEDYYDDYYGYDYH--DYRGGYEDPYYGYDDGY 396
Query: 735 NMPQRGGGGGGSG------GIGYPYPR---------APVFPGRGSYSNRGN-----YNRG 774
+ RGGG GG G G G P PR AP+ P RGS RG RG
Sbjct: 397 AVRGRGGGRGGRGAPPPPRGRGAPPPRGRAGYSQRGAPLGPPRGSRGGRGGPAQQQRGRG 456
Query: 775 GMPNRGNYNQNFRGRGNNRGYKNQSQGYNQWQQGQFWGQKPWSQ 818
+RGN N G+ GY Q Q WG +P +Q
Sbjct: 457 SRGSRGNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWGSQPIAQ 500
Score = 44.3 bits (103), Expect = 5e-04
Identities = 48/141 (34%), Positives = 56/141 (39%), Gaps = 41/141 (29%)
Query: 702 RGGGHRGRGGFNMRGGNFRGGAPGNRG--GYNRRGNM--PQRGGGGGGSGGIGYPYPRAP 757
RGGG GRG G GAP RG GY++RG P RG GG G A
Sbjct: 401 RGGGRGGRGAPPPPRGR---GAPPPRGRAGYSQRGAPLGPPRGSRGGRGGP-------AQ 450
Query: 758 VFPGRGSYSNRGNY--NRGGMPNRGNYNQ--NFRGRGNNR-------------------- 793
GRGS +RGN N GG YNQ + R + NN+
Sbjct: 451 QQRGRGSRGSRGNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWGSQPIAQQPLQQGGDYS 510
Query: 794 ---GYKNQSQGYNQWQQGQFW 811
GY N +Q + Q GQ W
Sbjct: 511 GNYGYNNDNQEFYQDTYGQQW 531
Score = 30.4 bits (67), Expect = 7.0
Identities = 36/141 (25%), Positives = 50/141 (35%), Gaps = 28/141 (19%)
Query: 129 EDENGDDQGFQEGEDELGDEEEGAGDENGH----------GEQQPQPPATQQQQPQQQRG 178
ED D G+ + G E+ G ++G+ G P PP + P + R
Sbjct: 367 EDYYDDYYGYDYHDYRGGYEDPYYGYDDGYAVRGRGGGRGGRGAPPPPRGRGAPPPRGR- 425
Query: 179 AAKEAAGKSSGPTSLFAVTVAPPGARQG-----QQQAGGKKKAEGGGGGGRPGAPAAGDG 233
A G GP P G+R G QQQ G + G GG G DG
Sbjct: 426 AGYSQRGAPLGP---------PRGSRGGRGGPAQQQRGRGSRGSRGNRGGNVGGKRKADG 476
Query: 234 KTEQKGGDKKRGVKRPREDHG 254
+ D KR +++ G
Sbjct: 477 YNQP---DSKRRQTNNQQNWG 494
>gi|5031755 heterogeneous nuclear ribonucleoprotein R isoform 2
[Homo sapiens]
Length = 633
Score = 55.1 bits (131), Expect = 3e-07
Identities = 58/224 (25%), Positives = 88/224 (39%), Gaps = 63/224 (28%)
Query: 647 ECFDEITYVELQKEEAQKLLEQYKEESKKALPPEKK--QNTGSKKSNKNKSGKNQF---- 700
+ DE+ E++ EE + +L A PP+KK + +++++++ + ++ +
Sbjct: 389 KAMDEMNGKEIEGEEIEIVL---------AKPPDKKRKERQAARQASRSTAYEDYYYHPP 439
Query: 701 ----------NRGGGHRGRG----------------GFNMRGGNFRGGAPGNRGGYNRRG 734
RGGG G G G++ ++RGG GY+
Sbjct: 440 PRMPPPIRGRGRGGGRGGYGYPPDYYGYEDYYDDYYGYDYH--DYRGGYEDPYYGYDDGY 497
Query: 735 NMPQRGGGGGGSG------GIGYPYPR---------APVFPGRGSYSNRGN-----YNRG 774
+ RGGG GG G G G P PR AP+ P RGS RG RG
Sbjct: 498 AVRGRGGGRGGRGAPPPPRGRGAPPPRGRAGYSQRGAPLGPPRGSRGGRGGPAQQQRGRG 557
Query: 775 GMPNRGNYNQNFRGRGNNRGYKNQSQGYNQWQQGQFWGQKPWSQ 818
+RGN N G+ GY Q Q WG +P +Q
Sbjct: 558 SRGSRGNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWGSQPIAQ 601
Score = 44.3 bits (103), Expect = 5e-04
Identities = 48/141 (34%), Positives = 56/141 (39%), Gaps = 41/141 (29%)
Query: 702 RGGGHRGRGGFNMRGGNFRGGAPGNRG--GYNRRGNM--PQRGGGGGGSGGIGYPYPRAP 757
RGGG GRG G GAP RG GY++RG P RG GG G A
Sbjct: 502 RGGGRGGRGAPPPPRGR---GAPPPRGRAGYSQRGAPLGPPRGSRGGRGGP-------AQ 551
Query: 758 VFPGRGSYSNRGNY--NRGGMPNRGNYNQ--NFRGRGNNR-------------------- 793
GRGS +RGN N GG YNQ + R + NN+
Sbjct: 552 QQRGRGSRGSRGNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWGSQPIAQQPLQQGGDYS 611
Query: 794 ---GYKNQSQGYNQWQQGQFW 811
GY N +Q + Q GQ W
Sbjct: 612 GNYGYNNDNQEFYQDTYGQQW 632
Score = 30.4 bits (67), Expect = 7.0
Identities = 36/141 (25%), Positives = 50/141 (35%), Gaps = 28/141 (19%)
Query: 129 EDENGDDQGFQEGEDELGDEEEGAGDENGH----------GEQQPQPPATQQQQPQQQRG 178
ED D G+ + G E+ G ++G+ G P PP + P + R
Sbjct: 468 EDYYDDYYGYDYHDYRGGYEDPYYGYDDGYAVRGRGGGRGGRGAPPPPRGRGAPPPRGR- 526
Query: 179 AAKEAAGKSSGPTSLFAVTVAPPGARQG-----QQQAGGKKKAEGGGGGGRPGAPAAGDG 233
A G GP P G+R G QQQ G + G GG G DG
Sbjct: 527 AGYSQRGAPLGP---------PRGSRGGRGGPAQQQRGRGSRGSRGNRGGNVGGKRKADG 577
Query: 234 KTEQKGGDKKRGVKRPREDHG 254
+ D KR +++ G
Sbjct: 578 YNQP---DSKRRQTNNQQNWG 595
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 54.7 bits (130), Expect = 3e-07
Identities = 70/307 (22%), Positives = 119/307 (38%), Gaps = 39/307 (12%)
Query: 6 VNVKKLKVSE--LKEELKKRRLSDKGLKAELMERLQAALDD---------EEAGGRPAME 54
V KLKV ++E +++ ++ D+ K+E+ E L A ++ +EA E
Sbjct: 441 VEAPKLKVQHKFVEEIIEETKVEDE--KSEMEEALTAITEELAVSMKEEKKEAAEEKEEE 498
Query: 55 PGNGSLDLGGDSAGRSGAGLEQEAAAG------GDEEEEEEEEEEEGISALDGDQMELGE 108
P ++ + E + G G EEEEEE+E + A +G + G
Sbjct: 499 PEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGS 558
Query: 109 ENGAAGAADSGPMEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPAT 168
G + G E E E E +++ +E +E+ +EE D ++ + P
Sbjct: 559 SEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPV- 617
Query: 169 QQQQPQQQRGAAK------EAAGKSSGPTSLFAVTVAPPGARQGQQQAG----GKKKAEG 218
+ P +++G + E GKS P S P + ++ G K E
Sbjct: 618 -PKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEE 676
Query: 219 GGGGGRPGAPA------AGDGKTEQKGGDKKRGVKRPREDHGRGYFEYIEENKYSRAKSP 272
P +P A GK EQK ++K + P+E+ E + K
Sbjct: 677 KAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEE--KPKDVPEKKKA 734
Query: 273 QPPVEEE 279
+ PV+EE
Sbjct: 735 ESPVKEE 741
Score = 34.3 bits (77), Expect = 0.48
Identities = 40/159 (25%), Positives = 67/159 (42%), Gaps = 20/159 (12%)
Query: 4 SPVNVKKLKVS-----ELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNG 58
SPV K K + +EE K+ + + K K E E + +++ P E
Sbjct: 685 SPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVA 744
Query: 59 SLDLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADS 118
+ S LE+E G ++E+E+E+ G +G E G + GA G+
Sbjct: 745 EVVTITKSVK---VHLEKETKEEGKPLQQEKEKEKAGG---EGGSEEEGSDKGAKGS--- 795
Query: 119 GPMEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENG 157
+E+ A NG+ +G +E E E ++ G +E G
Sbjct: 796 ---RKEDIAV---NGEVEGKEEVEQETKEKGSGREEEKG 828
Score = 33.9 bits (76), Expect = 0.63
Identities = 65/297 (21%), Positives = 113/297 (38%), Gaps = 57/297 (19%)
Query: 4 SPVNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSLDLG 63
SPV K E+KEE ++ ++G + E E A D E GG + + G+ + G
Sbjct: 511 SPV---KATAPEVKEEEGEKE-EEEGQEEEEEEDEGAKSDQAEEGG--SEKEGSSEKEEG 564
Query: 64 GDSAGRSGAGLEQEAAAGGDEEEEEEEEE------------------------------E 93
G + A E E A +E++ EE+ E E
Sbjct: 565 EQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEE 624
Query: 94 EGISALDGDQMELG----------EENGAAGAADSGPMEEEEAASEDENGDDQGFQEGED 143
+G S + +E EE G + S P+EE+ + ++ ++ +
Sbjct: 625 KGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKS-PVEEKGKSPVSKSPVEEKAKSPVP 683
Query: 144 ELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAAKEAAGK-------SSGPTSLFAV 196
+ EE + E G GEQ+ + ++ P++++ KE K + P AV
Sbjct: 684 KSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAV 743
Query: 197 TVAPPGARQGQQQAGGKKKAEGGG-GGGRPGAPAAGDGKTEQKGGDKKRGVKRPRED 252
+ + + K EG + A G+G +E++G DK G K R++
Sbjct: 744 AEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDK--GAKGSRKE 798
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 54.7 bits (130), Expect = 3e-07
Identities = 70/307 (22%), Positives = 119/307 (38%), Gaps = 39/307 (12%)
Query: 6 VNVKKLKVSE--LKEELKKRRLSDKGLKAELMERLQAALDD---------EEAGGRPAME 54
V KLKV ++E +++ ++ D+ K+E+ E L A ++ +EA E
Sbjct: 65 VEAPKLKVQHKFVEEIIEETKVEDE--KSEMEEALTAITEELAVSMKEEKKEAAEEKEEE 122
Query: 55 PGNGSLDLGGDSAGRSGAGLEQEAAAG------GDEEEEEEEEEEEGISALDGDQMELGE 108
P ++ + E + G G EEEEEE+E + A +G + G
Sbjct: 123 PEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGS 182
Query: 109 ENGAAGAADSGPMEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPAT 168
G + G E E E E +++ +E +E+ +EE D ++ + P
Sbjct: 183 SEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPV- 241
Query: 169 QQQQPQQQRGAAK------EAAGKSSGPTSLFAVTVAPPGARQGQQQAG----GKKKAEG 218
+ P +++G + E GKS P S P + ++ G K E
Sbjct: 242 -PKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEE 300
Query: 219 GGGGGRPGAPA------AGDGKTEQKGGDKKRGVKRPREDHGRGYFEYIEENKYSRAKSP 272
P +P A GK EQK ++K + P+E+ E + K
Sbjct: 301 KAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEE--KPKDVPEKKKA 358
Query: 273 QPPVEEE 279
+ PV+EE
Sbjct: 359 ESPVKEE 365
Score = 34.3 bits (77), Expect = 0.48
Identities = 40/159 (25%), Positives = 67/159 (42%), Gaps = 20/159 (12%)
Query: 4 SPVNVKKLKVS-----ELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNG 58
SPV K K + +EE K+ + + K K E E + +++ P E
Sbjct: 309 SPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVA 368
Query: 59 SLDLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADS 118
+ S LE+E G ++E+E+E+ G +G E G + GA G+
Sbjct: 369 EVVTITKSVK---VHLEKETKEEGKPLQQEKEKEKAGG---EGGSEEEGSDKGAKGS--- 419
Query: 119 GPMEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENG 157
+E+ A NG+ +G +E E E ++ G +E G
Sbjct: 420 ---RKEDIAV---NGEVEGKEEVEQETKEKGSGREEEKG 452
Score = 33.9 bits (76), Expect = 0.63
Identities = 65/297 (21%), Positives = 113/297 (38%), Gaps = 57/297 (19%)
Query: 4 SPVNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSLDLG 63
SPV K E+KEE ++ ++G + E E A D E GG + + G+ + G
Sbjct: 135 SPV---KATAPEVKEEEGEKE-EEEGQEEEEEEDEGAKSDQAEEGG--SEKEGSSEKEEG 188
Query: 64 GDSAGRSGAGLEQEAAAGGDEEEEEEEEE------------------------------E 93
G + A E E A +E++ EE+ E E
Sbjct: 189 EQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEE 248
Query: 94 EGISALDGDQMELG----------EENGAAGAADSGPMEEEEAASEDENGDDQGFQEGED 143
+G S + +E EE G + S P+EE+ + ++ ++ +
Sbjct: 249 KGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKS-PVEEKGKSPVSKSPVEEKAKSPVP 307
Query: 144 ELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAAKEAAGK-------SSGPTSLFAV 196
+ EE + E G GEQ+ + ++ P++++ KE K + P AV
Sbjct: 308 KSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAV 367
Query: 197 TVAPPGARQGQQQAGGKKKAEGGG-GGGRPGAPAAGDGKTEQKGGDKKRGVKRPRED 252
+ + + K EG + A G+G +E++G DK G K R++
Sbjct: 368 AEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDK--GAKGSRKE 422
>gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo
sapiens]
Length = 1101
Score = 54.7 bits (130), Expect = 3e-07
Identities = 66/256 (25%), Positives = 95/256 (37%), Gaps = 32/256 (12%)
Query: 46 EAGGRPAMEPGNGSLDLGGDSAG------RSGAGLEQEAAAGGDEE----------EEEE 89
E G EPG G LD+ ++ G +G E AGG +E EE E
Sbjct: 656 EVGEDKQAEPG-GRLDIREEAEGSPETKVEAGKASEDRGEAGGSQETKVRLREGSREETE 714
Query: 90 EEEEEGISALDGDQMELGEENGAAGAADSGPMEEEEAASEDENGDDQGFQEGED-ELGDE 148
+EE+ D ME G + E+E EDE ++ + G D E G +
Sbjct: 715 AKEEKSKGQKKADSMEAKGVEEPGGDEYTDEKEKEIEREEDEQREEAQVEAGRDLEQGAQ 774
Query: 149 EEGAGDENGHGEQQPQPPATQQQQPQQQRGAAKEAAGKSSGPTSLFAVTVAPPGARQGQQ 208
E+ +E Q+ + ++ + + QR A K G + +P A +G
Sbjct: 775 EDQVAEEKWEVVQKQEAEGVREDEDKGQREKGYHEARKDQGDGE---DSRSPEAATEG-- 829
Query: 209 QAGGKKKAEGGGGGGRPGAPAAGDGKTEQKGGDKKRGVKRPRED---HGRGYFEYIEENK 265
AG K G G G AG E+ + GV D G + +EE
Sbjct: 830 GAGEVSKERESGDGEAEGDQRAGGYYLEEDTLSEGSGVASLEVDCAKEGNPHSSEMEE-- 887
Query: 266 YSRAKSPQPPVEEEDE 281
+PQPP EE E
Sbjct: 888 ----VAPQPPQPEEME 899
Score = 39.3 bits (90), Expect = 0.015
Identities = 32/118 (27%), Positives = 53/118 (44%), Gaps = 18/118 (15%)
Query: 76 QEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGPMEEEEAASEDENGDD 135
Q+ A G E+E++ + E+G DQ + GE++ + AA G E E +G+
Sbjct: 787 QKQEAEGVREDEDKGQREKGYHEARKDQGD-GEDSRSPEAATEGGAGEVSKERESGDGEA 845
Query: 136 QGFQEG------EDELGD-------EEEGAGDENGHGEQQ----PQPPATQQQQPQQQ 176
+G Q ED L + E + A + N H + PQPP ++ +P+ Q
Sbjct: 846 EGDQRAGGYYLEEDTLSEGSGVASLEVDCAKEGNPHSSEMEEVAPQPPQPEEMEPEGQ 903
Score = 31.6 bits (70), Expect = 3.1
Identities = 45/178 (25%), Positives = 76/178 (42%), Gaps = 14/178 (7%)
Query: 79 AAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGPMEEEEAASEDENGDDQGF 138
+AG E EEE EE +SA D LG + SG +E E A + G
Sbjct: 593 SAGPRPEVEEENGEEVFLSAYDDLSPLLGPKPPI--WKGSGSLEGEAAGCGRQALGQGGE 650
Query: 139 QEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAAKEAAGKSSG--PTSLFAV 196
++ E+G++++ E G G + A + + + G A E G++ G T +
Sbjct: 651 EQACWEVGEDKQA---EPG-GRLDIREEAEGSPETKVEAGKASEDRGEAGGSQETKVRLR 706
Query: 197 TVAPPGARQGQQQAGGKKKAEG--GGGGGRPGAPAAGDGKTEQKGGDKKRGVKRPRED 252
+ ++++ G+KKA+ G PG GD T++K + +R RE+
Sbjct: 707 EGSREETEAKEEKSKGQKKADSMEAKGVEEPG----GDEYTDEKEKEIEREEDEQREE 760
>gi|158966674 proline-rich protein HaeIII subfamily 2 [Homo sapiens]
Length = 166
Score = 54.3 bits (129), Expect = 5e-07
Identities = 39/146 (26%), Positives = 61/146 (41%), Gaps = 9/146 (6%)
Query: 97 SALDGDQMELGEENGAAGAADSGPMEEEEAASEDENGDDQGFQEGEDELGD------EEE 150
SA D D+ ++ +E+ +D G + E+ E+ G G Q+ + GD ++
Sbjct: 15 SAQDLDE-DVSQEDVPLVISDGG--DSEQFIDEERQGPPLGGQQSQPSAGDGNQNDGPQQ 71
Query: 151 GAGDENGHGEQQPQPPATQQQQPQQQRGAAKEAAGKSSGPTSLFAVTVAPPGARQGQQQA 210
G + G +Q P PP + Q P QQ G G+ GP P G QG Q
Sbjct: 72 GPPQQGGQQQQGPPPPQGKPQGPPQQGGHPPPPQGRPQGPPQQGGHPRPPRGRPQGPPQQ 131
Query: 211 GGKKKAEGGGGGGRPGAPAAGDGKTE 236
GG ++ G+P P G+ +
Sbjct: 132 GGHQQGPPPPPPGKPQGPPPQGGRPQ 157
Score = 35.0 bits (79), Expect = 0.28
Identities = 37/149 (24%), Positives = 52/149 (34%), Gaps = 30/149 (20%)
Query: 81 GGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGPMEEEEAASEDENGDD--QGF 138
GGD E+ +EE + Q G+ N G P + + + G QG
Sbjct: 35 GGDSEQFIDEERQGPPLGGQQSQPSAGDGNQNDGPQQGPPQQ----GGQQQQGPPPPQGK 90
Query: 139 QEGEDELGDEE-------EGAGDENGHGEQQPQPPATQQQQPQQQRGAAKEAAGKSSGPT 191
+G + G +G + GH P+PP + Q P QQ G GP
Sbjct: 91 PQGPPQQGGHPPPPQGRPQGPPQQGGH----PRPPRGRPQGPPQQ-------GGHQQGPP 139
Query: 192 SLFAVTVAPPGARQGQQQAGGKKKAEGGG 220
PPG QG GG+ + G
Sbjct: 140 P------PPPGKPQGPPPQGGRPQGPPQG 162
>gi|4826944 proline-rich protein HaeIII subfamily 2 [Homo sapiens]
Length = 166
Score = 54.3 bits (129), Expect = 5e-07
Identities = 39/146 (26%), Positives = 61/146 (41%), Gaps = 9/146 (6%)
Query: 97 SALDGDQMELGEENGAAGAADSGPMEEEEAASEDENGDDQGFQEGEDELGD------EEE 150
SA D D+ ++ +E+ +D G + E+ E+ G G Q+ + GD ++
Sbjct: 15 SAQDLDE-DVSQEDVPLVISDGG--DSEQFIDEERQGPPLGGQQSQPSAGDGNQNDGPQQ 71
Query: 151 GAGDENGHGEQQPQPPATQQQQPQQQRGAAKEAAGKSSGPTSLFAVTVAPPGARQGQQQA 210
G + G +Q P PP + Q P QQ G G+ GP P G QG Q
Sbjct: 72 GPPQQGGQQQQGPPPPQGKPQGPPQQGGHPPPPQGRPQGPPQQGGHPRPPRGRPQGPPQQ 131
Query: 211 GGKKKAEGGGGGGRPGAPAAGDGKTE 236
GG ++ G+P P G+ +
Sbjct: 132 GGHQQGPPPPPPGKPQGPPPQGGRPQ 157
Score = 35.0 bits (79), Expect = 0.28
Identities = 37/149 (24%), Positives = 52/149 (34%), Gaps = 30/149 (20%)
Query: 81 GGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGPMEEEEAASEDENGDD--QGF 138
GGD E+ +EE + Q G+ N G P + + + G QG
Sbjct: 35 GGDSEQFIDEERQGPPLGGQQSQPSAGDGNQNDGPQQGPPQQ----GGQQQQGPPPPQGK 90
Query: 139 QEGEDELGDEE-------EGAGDENGHGEQQPQPPATQQQQPQQQRGAAKEAAGKSSGPT 191
+G + G +G + GH P+PP + Q P QQ G GP
Sbjct: 91 PQGPPQQGGHPPPPQGRPQGPPQQGGH----PRPPRGRPQGPPQQ-------GGHQQGPP 139
Query: 192 SLFAVTVAPPGARQGQQQAGGKKKAEGGG 220
PPG QG GG+ + G
Sbjct: 140 P------PPPGKPQGPPPQGGRPQGPPQG 162
>gi|228008295 synaptotagmin binding, cytoplasmic RNA interacting
protein isoform 4 [Homo sapiens]
Length = 588
Score = 53.9 bits (128), Expect = 6e-07
Identities = 64/221 (28%), Positives = 82/221 (37%), Gaps = 60/221 (27%)
Query: 655 VELQKEEAQKLLEQYKEESKKALPPEKKQNTGSKKSNKNKSGKNQF-------------- 700
V+ +E K LE E A PP++K+ ++ + ++ KNQ
Sbjct: 350 VKAMEEMNGKDLEGENIEIVFAKPPDQKRK---ERKAQRQAAKNQMYDDYYYYGPPHMPP 406
Query: 701 -NRGGGHRGRGGF---------------------NMRGG---------NFRGGAPGNRGG 729
RG G GRGG+ N RGG +F+ GA G RGG
Sbjct: 407 PTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGGYEDPYYGYEDFQVGARG-RGG 465
Query: 730 YNRRGNMPQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRGNYNQNFRG- 788
RG P RG G G R RG RG G RG + RG
Sbjct: 466 RGARGAAPSRGRGAAPPRGRAGYSQRGGPGSARGVRGARG----GAQQQRGRGVRGARGG 521
Query: 789 RGNNRGYKNQSQGYNQ------WQQGQFWGQKPWSQHYHQG 823
RG N G K ++ GYNQ Q WG +P +Q QG
Sbjct: 522 RGGNVGGKRKADGYNQPDSKRRQTNNQNWGSQPIAQQPLQG 562
Score = 43.5 bits (101), Expect = 8e-04
Identities = 41/133 (30%), Positives = 51/133 (38%), Gaps = 30/133 (22%)
Query: 705 GHRGRGGFNMRGG---NFRGGAPGN-RGGYNRRGNMPQRGGGGGGSGGIGYPYPRAPVFP 760
G RGRGG RG RG AP R GY++RG G G GG R
Sbjct: 459 GARGRGGRGARGAAPSRGRGAAPPRGRAGYSQRGGPGSARGVRGARGGAQQQRGRGV--- 515
Query: 761 GRGSYSNRGN----------YNRGGMPNRGNYNQNFRGR------------GNNRGYKNQ 798
RG+ RG YN+ R NQN+ + N GYK++
Sbjct: 516 -RGARGGRGGNVGGKRKADGYNQPDSKRRQTNNQNWGSQPIAQQPLQGGDHSGNYGYKSE 574
Query: 799 SQGYNQWQQGQFW 811
+Q + Q GQ W
Sbjct: 575 NQEFYQDTFGQQW 587
Score = 31.2 bits (69), Expect = 4.1
Identities = 30/108 (27%), Positives = 40/108 (37%), Gaps = 10/108 (9%)
Query: 137 GFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAAKEAAGKSSGPTSLFAV 196
G+++ D + GA G G + P + P + R + G P S V
Sbjct: 445 GYEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAGYSQRGG----PGSARGV 500
Query: 197 TVAPPGARQGQQQAGGKKKAEGGGGGGRPGAPAAGDGKTEQKGGDKKR 244
A GA QQQ G + GG GG G DG + D KR
Sbjct: 501 RGARGGA---QQQRGRGVRGARGGRGGNVGGKRKADGYNQP---DSKR 542
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.133 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,152,953
Number of Sequences: 37866
Number of extensions: 2404947
Number of successful extensions: 37672
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 477
Number of HSP's successfully gapped in prelim test: 1084
Number of HSP's that attempted gapping in prelim test: 17065
Number of HSP's gapped (non-prelim): 10851
length of query: 825
length of database: 18,247,518
effective HSP length: 111
effective length of query: 714
effective length of database: 14,044,392
effective search space: 10027695888
effective search space used: 10027695888
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.