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Search of human proteins with 74027249
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|74027249 tripartite motif-containing 33 protein isoform
alpha [Homo sapiens]
(1127 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|74027249 tripartite motif-containing 33 protein isoform alpha... 2295 0.0
gi|74027251 tripartite motif-containing 33 protein isoform beta ... 2253 0.0
gi|47419911 transcriptional intermediary factor 1 alpha isoform ... 953 0.0
gi|47419909 transcriptional intermediary factor 1 alpha isoform ... 928 0.0
gi|5032179 tripartite motif-containing 28 protein [Homo sapiens] 340 4e-93
gi|209977097 tripartite motif-containing 66 [Homo sapiens] 234 5e-61
gi|224548923 tripartite motif-containing 45 isoform 2 [Homo sapi... 140 9e-33
gi|224548921 tripartite motif-containing 45 isoform 1 [Homo sapi... 140 9e-33
gi|84993742 tripartite motif-containing 71 [Homo sapiens] 104 5e-22
gi|134133279 SP140 nuclear body protein-like [Homo sapiens] 103 9e-22
gi|217330601 SP140 nuclear body protein isoform 1 [Homo sapiens] 99 2e-20
gi|30794216 tripartite motif-containing 56 [Homo sapiens] 97 1e-19
gi|122939208 nuclear antigen Sp100 isoform 1 [Homo sapiens] 94 6e-19
gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo... 93 1e-18
gi|190343006 SP110 nuclear body protein isoform c [Homo sapiens] 93 1e-18
gi|32454739 tripartite motif-containing 3 [Homo sapiens] 91 5e-18
gi|32454737 tripartite motif-containing 3 [Homo sapiens] 91 5e-18
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 89 2e-17
gi|194248079 tripartite motif-containing 2 isoform 1 [Homo sapiens] 87 1e-16
gi|194248081 tripartite motif-containing 2 isoform 2 [Homo sapiens] 86 2e-16
gi|148833499 midline 1 [Homo sapiens] 84 8e-16
gi|4557753 midline 1 [Homo sapiens] 84 8e-16
gi|15451852 midline 1 [Homo sapiens] 84 8e-16
gi|67089160 promyelocytic leukemia protein isoform 11 [Homo sapi... 83 2e-15
gi|67089157 promyelocytic leukemia protein isoform 2 [Homo sapiens] 83 2e-15
gi|15451765 promyelocytic leukemia protein isoform 9 [Homo sapiens] 83 2e-15
gi|67089154 promyelocytic leukemia protein isoform 8 [Homo sapiens] 83 2e-15
gi|4505903 promyelocytic leukemia protein isoform 6 [Homo sapiens] 83 2e-15
gi|15451775 promyelocytic leukemia protein isoform 7 [Homo sapiens] 83 2e-15
gi|15451779 promyelocytic leukemia protein isoform 10 [Homo sapi... 83 2e-15
>gi|74027249 tripartite motif-containing 33 protein isoform alpha
[Homo sapiens]
Length = 1127
Score = 2295 bits (5948), Expect = 0.0
Identities = 1127/1127 (100%), Positives = 1127/1127 (100%)
Query: 1 MAENKGGGEAESGGGGSGSAPVTAGAAGPAAQEAEPPLTAVLVEEEEEEGGRAGAEGGAA 60
MAENKGGGEAESGGGGSGSAPVTAGAAGPAAQEAEPPLTAVLVEEEEEEGGRAGAEGGAA
Sbjct: 1 MAENKGGGEAESGGGGSGSAPVTAGAAGPAAQEAEPPLTAVLVEEEEEEGGRAGAEGGAA 60
Query: 61 GPDDGGVAAASSGSAQAASSPAASVGTGVAGGAVSTPAPAPASAPAPGPSAGPPPGPPAS 120
GPDDGGVAAASSGSAQAASSPAASVGTGVAGGAVSTPAPAPASAPAPGPSAGPPPGPPAS
Sbjct: 61 GPDDGGVAAASSGSAQAASSPAASVGTGVAGGAVSTPAPAPASAPAPGPSAGPPPGPPAS 120
Query: 121 LLDTCAVCQQSLQSRREAEPKLLPCLHSFCLRCLPEPERQLSVPIPGGSNGDIQQVGVIR 180
LLDTCAVCQQSLQSRREAEPKLLPCLHSFCLRCLPEPERQLSVPIPGGSNGDIQQVGVIR
Sbjct: 121 LLDTCAVCQQSLQSRREAEPKLLPCLHSFCLRCLPEPERQLSVPIPGGSNGDIQQVGVIR 180
Query: 181 CPVCRQECRQIDLVDNYFVKDTSEAPSSSDEKSEQVCTSCEDNASAVGFCVECGEWLCKT 240
CPVCRQECRQIDLVDNYFVKDTSEAPSSSDEKSEQVCTSCEDNASAVGFCVECGEWLCKT
Sbjct: 181 CPVCRQECRQIDLVDNYFVKDTSEAPSSSDEKSEQVCTSCEDNASAVGFCVECGEWLCKT 240
Query: 241 CIEAHQRVKFTKDHLIRKKEDVSESVGASGQRPVFCPVHKQEQLKLFCETCDRLTCRDCQ 300
CIEAHQRVKFTKDHLIRKKEDVSESVGASGQRPVFCPVHKQEQLKLFCETCDRLTCRDCQ
Sbjct: 241 CIEAHQRVKFTKDHLIRKKEDVSESVGASGQRPVFCPVHKQEQLKLFCETCDRLTCRDCQ 300
Query: 301 LLEHKEHRYQFLEEAFQNQKGAIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQ 360
LLEHKEHRYQFLEEAFQNQKGAIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQ
Sbjct: 301 LLEHKEHRYQFLEEAFQNQKGAIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQ 360
Query: 361 EIKVAIFTLINEINKKGKSLLQQLENVTKERQMKLLQQQNDITGLSRQVKHVMNFTNWAI 420
EIKVAIFTLINEINKKGKSLLQQLENVTKERQMKLLQQQNDITGLSRQVKHVMNFTNWAI
Sbjct: 361 EIKVAIFTLINEINKKGKSLLQQLENVTKERQMKLLQQQNDITGLSRQVKHVMNFTNWAI 420
Query: 421 ASGSSTALLYSKRLITFQLRHILKARCDPVPAANGAIRFHCDPTFWAKNVVNLGNLVIES 480
ASGSSTALLYSKRLITFQLRHILKARCDPVPAANGAIRFHCDPTFWAKNVVNLGNLVIES
Sbjct: 421 ASGSSTALLYSKRLITFQLRHILKARCDPVPAANGAIRFHCDPTFWAKNVVNLGNLVIES 480
Query: 481 KPAPGYTPNVVVGQVPPGTNHISKTPGQINLAQLRLQHMQQQVYAQKHQQLQQMRMQQPP 540
KPAPGYTPNVVVGQVPPGTNHISKTPGQINLAQLRLQHMQQQVYAQKHQQLQQMRMQQPP
Sbjct: 481 KPAPGYTPNVVVGQVPPGTNHISKTPGQINLAQLRLQHMQQQVYAQKHQQLQQMRMQQPP 540
Query: 541 APVPTTTTTTQQHPRQAAPQMLQQQPPRLISVQTMQRGNMNCGAFQAHQMRLAQNAARIP 600
APVPTTTTTTQQHPRQAAPQMLQQQPPRLISVQTMQRGNMNCGAFQAHQMRLAQNAARIP
Sbjct: 541 APVPTTTTTTQQHPRQAAPQMLQQQPPRLISVQTMQRGNMNCGAFQAHQMRLAQNAARIP 600
Query: 601 GIPRHSGPQYSMMQPHLQRQHSNPGHAGPFPVVSVHNTTINPTSPTTATMANANRGPTSP 660
GIPRHSGPQYSMMQPHLQRQHSNPGHAGPFPVVSVHNTTINPTSPTTATMANANRGPTSP
Sbjct: 601 GIPRHSGPQYSMMQPHLQRQHSNPGHAGPFPVVSVHNTTINPTSPTTATMANANRGPTSP 660
Query: 661 SVTAIELIPSVTNPENLPSLPDIPPIQLEDAGSSSLDNLLSRYISGSHLPPQPTSTMNPS 720
SVTAIELIPSVTNPENLPSLPDIPPIQLEDAGSSSLDNLLSRYISGSHLPPQPTSTMNPS
Sbjct: 661 SVTAIELIPSVTNPENLPSLPDIPPIQLEDAGSSSLDNLLSRYISGSHLPPQPTSTMNPS 720
Query: 721 PGPSALSPGSSGLSNSHTPVRPPSTSSTGSRGSCGSSGRTAEKTSLSFKSDQVKVKQEPG 780
PGPSALSPGSSGLSNSHTPVRPPSTSSTGSRGSCGSSGRTAEKTSLSFKSDQVKVKQEPG
Sbjct: 721 PGPSALSPGSSGLSNSHTPVRPPSTSSTGSRGSCGSSGRTAEKTSLSFKSDQVKVKQEPG 780
Query: 781 TEDEICSFSGGVKQEKTEDGRRSACMLSSPESSLTPPLSTNLHLESELDALASLENHVKI 840
TEDEICSFSGGVKQEKTEDGRRSACMLSSPESSLTPPLSTNLHLESELDALASLENHVKI
Sbjct: 781 TEDEICSFSGGVKQEKTEDGRRSACMLSSPESSLTPPLSTNLHLESELDALASLENHVKI 840
Query: 841 EPADMNESCKQSGLSSLVNGKSPIRSLMHRSARIGGDGNNKDDDPNEDWCAVCQNGGDLL 900
EPADMNESCKQSGLSSLVNGKSPIRSLMHRSARIGGDGNNKDDDPNEDWCAVCQNGGDLL
Sbjct: 841 EPADMNESCKQSGLSSLVNGKSPIRSLMHRSARIGGDGNNKDDDPNEDWCAVCQNGGDLL 900
Query: 901 CCEKCPKVFHLTCHVPTLLSFPSGDWICTFCRDIGKPEVEYDCDNLQHSKKGKTAQGLSP 960
CCEKCPKVFHLTCHVPTLLSFPSGDWICTFCRDIGKPEVEYDCDNLQHSKKGKTAQGLSP
Sbjct: 901 CCEKCPKVFHLTCHVPTLLSFPSGDWICTFCRDIGKPEVEYDCDNLQHSKKGKTAQGLSP 960
Query: 961 VDQRKCERLLLYLYCHELSIEFQEPVPASIPNYYKIIKKPMDLSTVKKKLQKKHSQHYQI 1020
VDQRKCERLLLYLYCHELSIEFQEPVPASIPNYYKIIKKPMDLSTVKKKLQKKHSQHYQI
Sbjct: 961 VDQRKCERLLLYLYCHELSIEFQEPVPASIPNYYKIIKKPMDLSTVKKKLQKKHSQHYQI 1020
Query: 1021 PDDFVADVRLIFKNCERFNEMMKVVQVYADTQEINLKADSEVAQAGKAVALYFEDKLTEI 1080
PDDFVADVRLIFKNCERFNEMMKVVQVYADTQEINLKADSEVAQAGKAVALYFEDKLTEI
Sbjct: 1021 PDDFVADVRLIFKNCERFNEMMKVVQVYADTQEINLKADSEVAQAGKAVALYFEDKLTEI 1080
Query: 1081 YSDRTFAPLPEFEQEEDDGEVTEDSDEDFIQPRRKRLKSDERPVHIK 1127
YSDRTFAPLPEFEQEEDDGEVTEDSDEDFIQPRRKRLKSDERPVHIK
Sbjct: 1081 YSDRTFAPLPEFEQEEDDGEVTEDSDEDFIQPRRKRLKSDERPVHIK 1127
>gi|74027251 tripartite motif-containing 33 protein isoform beta [Homo
sapiens]
Length = 1110
Score = 2253 bits (5837), Expect = 0.0
Identities = 1110/1127 (98%), Positives = 1110/1127 (98%), Gaps = 17/1127 (1%)
Query: 1 MAENKGGGEAESGGGGSGSAPVTAGAAGPAAQEAEPPLTAVLVEEEEEEGGRAGAEGGAA 60
MAENKGGGEAESGGGGSGSAPVTAGAAGPAAQEAEPPLTAVLVEEEEEEGGRAGAEGGAA
Sbjct: 1 MAENKGGGEAESGGGGSGSAPVTAGAAGPAAQEAEPPLTAVLVEEEEEEGGRAGAEGGAA 60
Query: 61 GPDDGGVAAASSGSAQAASSPAASVGTGVAGGAVSTPAPAPASAPAPGPSAGPPPGPPAS 120
GPDDGGVAAASSGSAQAASSPAASVGTGVAGGAVSTPAPAPASAPAPGPSAGPPPGPPAS
Sbjct: 61 GPDDGGVAAASSGSAQAASSPAASVGTGVAGGAVSTPAPAPASAPAPGPSAGPPPGPPAS 120
Query: 121 LLDTCAVCQQSLQSRREAEPKLLPCLHSFCLRCLPEPERQLSVPIPGGSNGDIQQVGVIR 180
LLDTCAVCQQSLQSRREAEPKLLPCLHSFCLRCLPEPERQLSVPIPGGSNGDIQQVGVIR
Sbjct: 121 LLDTCAVCQQSLQSRREAEPKLLPCLHSFCLRCLPEPERQLSVPIPGGSNGDIQQVGVIR 180
Query: 181 CPVCRQECRQIDLVDNYFVKDTSEAPSSSDEKSEQVCTSCEDNASAVGFCVECGEWLCKT 240
CPVCRQECRQIDLVDNYFVKDTSEAPSSSDEKSEQVCTSCEDNASAVGFCVECGEWLCKT
Sbjct: 181 CPVCRQECRQIDLVDNYFVKDTSEAPSSSDEKSEQVCTSCEDNASAVGFCVECGEWLCKT 240
Query: 241 CIEAHQRVKFTKDHLIRKKEDVSESVGASGQRPVFCPVHKQEQLKLFCETCDRLTCRDCQ 300
CIEAHQRVKFTKDHLIRKKEDVSESVGASGQRPVFCPVHKQEQLKLFCETCDRLTCRDCQ
Sbjct: 241 CIEAHQRVKFTKDHLIRKKEDVSESVGASGQRPVFCPVHKQEQLKLFCETCDRLTCRDCQ 300
Query: 301 LLEHKEHRYQFLEEAFQNQKGAIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQ 360
LLEHKEHRYQFLEEAFQNQKGAIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQ
Sbjct: 301 LLEHKEHRYQFLEEAFQNQKGAIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQ 360
Query: 361 EIKVAIFTLINEINKKGKSLLQQLENVTKERQMKLLQQQNDITGLSRQVKHVMNFTNWAI 420
EIKVAIFTLINEINKKGKSLLQQLENVTKERQMKLLQQQNDITGLSRQVKHVMNFTNWAI
Sbjct: 361 EIKVAIFTLINEINKKGKSLLQQLENVTKERQMKLLQQQNDITGLSRQVKHVMNFTNWAI 420
Query: 421 ASGSSTALLYSKRLITFQLRHILKARCDPVPAANGAIRFHCDPTFWAKNVVNLGNLVIES 480
ASGSSTALLYSKRLITFQLRHILKARCDPVPAANGAIRFHCDPTFWAKNVVNLGNLVIES
Sbjct: 421 ASGSSTALLYSKRLITFQLRHILKARCDPVPAANGAIRFHCDPTFWAKNVVNLGNLVIES 480
Query: 481 KPAPGYTPNVVVGQVPPGTNHISKTPGQINLAQLRLQHMQQQVYAQKHQQLQQMRMQQPP 540
KPAPGYTPNVVVGQVPPGTNHISKTPGQINLAQLRLQHMQQQVYAQKHQQLQQMRMQQPP
Sbjct: 481 KPAPGYTPNVVVGQVPPGTNHISKTPGQINLAQLRLQHMQQQVYAQKHQQLQQMRMQQPP 540
Query: 541 APVPTTTTTTQQHPRQAAPQMLQQQPPRLISVQTMQRGNMNCGAFQAHQMRLAQNAARIP 600
APVPTTTTTTQQHPRQAAPQMLQQQPPRLISVQTMQRGNMNCGAFQAHQMRLAQNAARIP
Sbjct: 541 APVPTTTTTTQQHPRQAAPQMLQQQPPRLISVQTMQRGNMNCGAFQAHQMRLAQNAARIP 600
Query: 601 GIPRHSGPQYSMMQPHLQRQHSNPGHAGPFPVVSVHNTTINPTSPTTATMANANRGPTSP 660
GIPRHSGPQYSMMQPHLQRQHSNPGHAGPFPVVSVHNTTINPTSPTTATMANANRGPTSP
Sbjct: 601 GIPRHSGPQYSMMQPHLQRQHSNPGHAGPFPVVSVHNTTINPTSPTTATMANANRGPTSP 660
Query: 661 SVTAIELIPSVTNPENLPSLPDIPPIQLEDAGSSSLDNLLSRYISGSHLPPQPTSTMNPS 720
SVTAIELIPSVTNPENLPSLPDIPPIQLEDAGSSSLDNLLSRYISGSHLPPQPTSTMNPS
Sbjct: 661 SVTAIELIPSVTNPENLPSLPDIPPIQLEDAGSSSLDNLLSRYISGSHLPPQPTSTMNPS 720
Query: 721 PGPSALSPGSSGLSNSHTPVRPPSTSSTGSRGSCGSSGRTAEKTSLSFKSDQVKVKQEPG 780
PGPSALSPGSSGLSNSHTPVRPPSTSSTGSRGSCGSSGRTAEKTSLSFKSDQVKVKQEPG
Sbjct: 721 PGPSALSPGSSGLSNSHTPVRPPSTSSTGSRGSCGSSGRTAEKTSLSFKSDQVKVKQEPG 780
Query: 781 TEDEICSFSGGVKQEKTEDGRRSACMLSSPESSLTPPLSTNLHLESELDALASLENHVKI 840
TEDEICSFSGGVKQEKTEDGRRSACMLSSPESSLTPPLSTNLHLESELDALASLENHVKI
Sbjct: 781 TEDEICSFSGGVKQEKTEDGRRSACMLSSPESSLTPPLSTNLHLESELDALASLENHVKI 840
Query: 841 EPADMNESCKQSGLSSLVNGKSPIRSLMHRSARIGGDGNNKDDDPNEDWCAVCQNGGDLL 900
EPADMNESCKQSGLSSLVNGKSPIRSLMHRSARIGGDGNNKDDDPNEDWCAVCQNGGDLL
Sbjct: 841 EPADMNESCKQSGLSSLVNGKSPIRSLMHRSARIGGDGNNKDDDPNEDWCAVCQNGGDLL 900
Query: 901 CCEKCPKVFHLTCHVPTLLSFPSGDWICTFCRDIGKPEVEYDCDNLQHSKKGKTAQGLSP 960
CCEKCPKVFHLTCHVPTLLSFPSGDWICTFCRDIGKPEVEYDCDNLQHSKKGKTAQGLSP
Sbjct: 901 CCEKCPKVFHLTCHVPTLLSFPSGDWICTFCRDIGKPEVEYDCDNLQHSKKGKTAQGLSP 960
Query: 961 VDQRKCERLLLYLYCHELSIEFQEPVPASIPNYYKIIKKPMDLSTVKKKLQKKHSQHYQI 1020
VDQRKCERLLLYLYCHELSIEFQEPVPASIPNYYKIIKKPMDLSTVKKKLQKKHSQHYQI
Sbjct: 961 VDQRKCERLLLYLYCHELSIEFQEPVPASIPNYYKIIKKPMDLSTVKKKLQKKHSQHYQI 1020
Query: 1021 PDDFVADVRLIFKNCERFNEMMKVVQVYADTQEINLKADSEVAQAGKAVALYFEDKLTEI 1080
PDDFVADVRLIFKNCERFNE ADSEVAQAGKAVALYFEDKLTEI
Sbjct: 1021 PDDFVADVRLIFKNCERFNE-----------------ADSEVAQAGKAVALYFEDKLTEI 1063
Query: 1081 YSDRTFAPLPEFEQEEDDGEVTEDSDEDFIQPRRKRLKSDERPVHIK 1127
YSDRTFAPLPEFEQEEDDGEVTEDSDEDFIQPRRKRLKSDERPVHIK
Sbjct: 1064 YSDRTFAPLPEFEQEEDDGEVTEDSDEDFIQPRRKRLKSDERPVHIK 1110
>gi|47419911 transcriptional intermediary factor 1 alpha isoform a
[Homo sapiens]
Length = 1050
Score = 953 bits (2463), Expect = 0.0
Identities = 543/1100 (49%), Positives = 694/1100 (63%), Gaps = 103/1100 (9%)
Query: 67 VAAASSGSAQAASSPAASVGTGVAGGAVSTPAPAPASAPAPGP-SAGPPPGPPASLLDTC 125
VA + +A AA+S AAS GG + P+ + GP S +LLDTC
Sbjct: 3 VAVEKAVAAAAAASAAAS------GGPSAAPSGENEAESRQGPDSERGGEAARLNLLDTC 56
Query: 126 AVCQQSLQSRREAEPKLLPCLHSFCLRCLPEPERQLSVPIP------------------G 167
AVC Q++QSR PKLLPCLHSFC RCLP P+R L +P P
Sbjct: 57 AVCHQNIQSRA---PKLLPCLHSFCQRCLPAPQRYLMLPAPMLGSAETPPPVPAPGSPVS 113
Query: 168 GSNGDIQQVGVIRCPVCRQECRQIDLVDNYFVKDTSEAPSSSDEKSEQVCTSCEDNASAV 227
GS+ QVGVIRCPVC QEC + ++DN+FVKDT+E PSS+ EKS QVCTSCEDNA A
Sbjct: 114 GSSPFATQVGVIRCPVCSQECAERHIIDNFFVKDTTEVPSSTVEKSNQVCTSCEDNAEAN 173
Query: 228 GFCVECGEWLCKTCIEAHQRVKFTKDHLIRKKEDVS-ESVGASGQRPVFCPVHKQEQLKL 286
GFCVEC EWLCKTCI AHQRVKFTKDH +R+KE+VS E+VG + QRPVFCP HK+EQLKL
Sbjct: 174 GFCVECVEWLCKTCIRAHQRVKFTKDHTVRQKEEVSPEAVGVTSQRPVFCPFHKKEQLKL 233
Query: 287 FCETCDRLTCRDCQLLEHKEHRYQFLEEAFQNQKGAIENLLAKLLEKKNYVHFAATQVQN 346
+CETCD+LTCRDCQLLEHKEHRYQF+EEAFQNQK I+ L+ KL+EK Y+ F Q+QN
Sbjct: 234 YCETCDKLTCRDCQLLEHKEHRYQFIEEAFQNQKVIIDTLITKLMEKTKYIKFTGNQIQN 293
Query: 347 RIKEVNETNKRVEQEIKVAIFTLINEINKKGKSLLQQLENVTKERQMKLLQQQNDITGLS 406
RI EVN+ K+VEQ+IKVAIFTL+ EINKKGK+LL QLE++ K+ +MKL+QQQ ++ GLS
Sbjct: 294 RIIEVNQNQKQVEQDIKVAIFTLMVEINKKGKALLHQLESLAKDHRMKLMQQQQEVAGLS 353
Query: 407 RQVKHVMNFTNWAIASGSSTALLYSKRLITFQLRHILKARCDPVPAANGAIRFHCDPTFW 466
+Q++HVM+F+ WA++SGSSTALLYSKRLIT++LRH+L+ARCD P N I+FHCDP+FW
Sbjct: 354 KQLEHVMHFSKWAVSSGSSTALLYSKRLITYRLRHLLRARCDASPVTNNTIQFHCDPSFW 413
Query: 467 AKNVVNLGNLVIESKPA----PGYTPNVVVGQVPPG---TNHISKTPGQINLAQLRLQHM 519
A+N++NLG+LVIE K + P P V PP +N +SK P QI+LAQLRLQHM
Sbjct: 414 AQNIINLGSLVIEDKESQPQMPKQNPVVEQNSQPPSGLSSNQLSKFPTQISLAQLRLQHM 473
Query: 520 QQQVYAQKHQQLQQMRMQQPPAPVPTTTTTTQQHPRQAAPQMLQQQPPRLISVQTMQRGN 579
QQQV AQ+ Q +Q+ PAPV Q P Q QQ PPRLI+ Q
Sbjct: 474 QQQVMAQRQQ------VQRRPAPVGLPNPR-MQGPIQQPSISHQQPPPRLINFQN-HSPK 525
Query: 580 MNCGAFQAH--QMRLAQNAARIPGIPRHSGPQYSMMQPHLQRQHSNPGH--AGPFPVVSV 635
N H Q+R N IPR + + L +Q +G +
Sbjct: 526 PNGPVLPPHPQQLRYPPNQ----NIPRQAIKPNPLQMAFLAQQAIKQWQISSGQGTPSTT 581
Query: 636 HNTTINPTSPTTATMANAN-RGPTSPSVTAIELIPSVTNPENLPSLPDIPPIQLEDAGSS 694
++T+ P+SPT + A + + SP I+L V NLPSLPDI + + +
Sbjct: 582 NSTSSTPSSPTITSAAGYDGKAFGSPM---IDLSSPVGGSYNLPSLPDI-----DCSSTI 633
Query: 695 SLDNLLSRYISGSHLPPQPTSTMN-PSPGPSALSPGSSG---LSNSHTPVRPPSTSSTGS 750
LDN++ + + H P+P S SP S SPG +G +++ H P+R PS SS GS
Sbjct: 634 MLDNIVRKDTNIDHGQPRPPSNRTVQSPNSSVPSPGLAGPVTMTSVHPPIRSPSASSVGS 693
Query: 751 RGSCGSSGRTAEKTSLS----FKSDQVKVKQEPGTEDEICSFSGG-VKQEKTEDGRRSAC 805
RGS GSS + A S + +++KQE E F VKQE E+ R
Sbjct: 694 RGSSGSSSKPAGADSTHKVPVVMLEPIRIKQENSGPPENYDFPVVIVKQESDEESR---- 749
Query: 806 MLSSPESSLTP-PLSTNLHLESELDALASLENHVKIEPADMNESCKQSGLSSLVNGKSPI 864
P+++ P + T+L L S + S E ++ + D + NGKS
Sbjct: 750 ----PQNANYPRSILTSLLLNSSQSS-TSEETVLRSDAPDSTGDQPGLHQDNSSNGKSEW 804
Query: 865 RSLMHRSARIGGDGNNKDDDPNEDWCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPSG 924
+S G+ K+DDPNEDWCAVCQNGG+LLCCEKCPKVFHL+CHVPTL +FPSG
Sbjct: 805 LDPSQKSPLHVGE-TRKEDDPNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSG 863
Query: 925 DWICTFCRDIGKPEVEYDCDNLQHSKKGKTAQGL---SPVDQRKCERLLLYLYCHELSIE 981
+WICTFCRD+ KPEVEYDCD H+ + K +GL +P+D+RKCERLLL+LYCHE+S+
Sbjct: 864 EWICTFCRDLSKPEVEYDCDAPSHNSEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLA 923
Query: 982 FQEPVPASIPNYYKIIKKPMDLSTVKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFNEM 1041
FQ+PVP ++P+YYKIIK PMDLST+KK+LQ+ +S Y P+DFVAD RLIF+NC FNE
Sbjct: 924 FQDPVPLTVPDYYKIIKNPMDLSTIKKRLQEDYSM-YSKPEDFVADFRLIFQNCAEFNE- 981
Query: 1042 MKVVQVYADTQEINLKADSEVAQAGKAVALYFEDKLTEIYSDRTFAPLPEFEQEEDDGEV 1101
DSEVA AG + YFE+ L +Y ++ F P PEF E +D +
Sbjct: 982 ----------------PDSEVANAGIKLENYFEELLKNLYPEKRF-PKPEFRNESEDNKF 1024
Query: 1102 TEDSDEDFIQPRRKRLKSDE 1121
++DSD+DF+QPR+KRLKS E
Sbjct: 1025 SDDSDDDFVQPRKKRLKSIE 1044
>gi|47419909 transcriptional intermediary factor 1 alpha isoform b
[Homo sapiens]
Length = 1016
Score = 928 bits (2399), Expect = 0.0
Identities = 526/1096 (47%), Positives = 683/1096 (62%), Gaps = 129/1096 (11%)
Query: 67 VAAASSGSAQAASSPAASVGTGVAGGAVSTPAPAPASAPAPGP-SAGPPPGPPASLLDTC 125
VA + +A AA+S AAS GG + P+ + GP S +LLDTC
Sbjct: 3 VAVEKAVAAAAAASAAAS------GGPSAAPSGENEAESRQGPDSERGGEAARLNLLDTC 56
Query: 126 AVCQQSLQSRREAEPKLLPCLHSFCLRCLPEPERQLSVPIP------------------G 167
AVC Q++QSR PKLLPCLHSFC RCLP P+R L +P P
Sbjct: 57 AVCHQNIQSRA---PKLLPCLHSFCQRCLPAPQRYLMLPAPMLGSAETPPPVPAPGSPVS 113
Query: 168 GSNGDIQQVGVIRCPVCRQECRQIDLVDNYFVKDTSEAPSSSDEKSEQVCTSCEDNASAV 227
GS+ QVGVIRCPVC QEC + ++DN+FVKDT+E PSS+ EKS QVCTSCEDNA A
Sbjct: 114 GSSPFATQVGVIRCPVCSQECAERHIIDNFFVKDTTEVPSSTVEKSNQVCTSCEDNAEAN 173
Query: 228 GFCVECGEWLCKTCIEAHQRVKFTKDHLIRKKEDVS-ESVGASGQRPVFCPVHKQEQLKL 286
GFCVEC EWLCKTCI AHQRVKFTKDH +R+KE+VS E+VG + QRPVFCP HK+EQLKL
Sbjct: 174 GFCVECVEWLCKTCIRAHQRVKFTKDHTVRQKEEVSPEAVGVTSQRPVFCPFHKKEQLKL 233
Query: 287 FCETCDRLTCRDCQLLEHKEHRYQFLEEAFQNQKGAIENLLAKLLEKKNYVHFAATQVQN 346
+CETCD+LTCRDCQLLEHKEHRYQF+EEAFQNQK I+ L+ KL+EK Y+ F Q+QN
Sbjct: 234 YCETCDKLTCRDCQLLEHKEHRYQFIEEAFQNQKVIIDTLITKLMEKTKYIKFTGNQIQN 293
Query: 347 RIKEVNETNKRVEQEIKVAIFTLINEINKKGKSLLQQLENVTKERQMKLLQQQNDITGLS 406
RI EVN+ K+VEQ+IKVAIFTL+ EINKKGK+LL QLE++ K+ +MKL+QQQ ++ GLS
Sbjct: 294 RIIEVNQNQKQVEQDIKVAIFTLMVEINKKGKALLHQLESLAKDHRMKLMQQQQEVAGLS 353
Query: 407 RQVKHVMNFTNWAIASGSSTALLYSKRLITFQLRHILKARCDPVPAANGAIRFHCDPTFW 466
+Q++HVM+F+ WA++SGSSTALLYSKRLIT++LRH+L+ARCD P N I+FHCDP+FW
Sbjct: 354 KQLEHVMHFSKWAVSSGSSTALLYSKRLITYRLRHLLRARCDASPVTNNTIQFHCDPSFW 413
Query: 467 AKNVVNLGNLVIESKPA----PGYTPNVVVGQVPP---GTNHISKTPGQINLAQLRLQHM 519
A+N++NLG+LVIE K + P P V PP +N +SK P QI+LAQLRLQHM
Sbjct: 414 AQNIINLGSLVIEDKESQPQMPKQNPVVEQNSQPPSGLSSNQLSKFPTQISLAQLRLQHM 473
Query: 520 QQQVYAQKHQQLQQMRMQQPPAPVPTTTTTTQQHPRQAAPQMLQQQPPRLISVQTMQRGN 579
QQ QQPP P P+ P + PP ++ N
Sbjct: 474 QQ---------------QQPP---PRLINFQNHSPKPNGPVL----PPHPQQLRYPPNQN 511
Query: 580 MNCGAFQAHQMRLAQNAARIPGIPRHSGPQYSMMQPHLQRQHSNPGHAGPFPVVSVHNTT 639
+ A + + +++A + Q +++ + G P + ++T+
Sbjct: 512 IPRQAIKPNPLQMA-----------------FLAQQAIKQWQISSGQGTP---STTNSTS 551
Query: 640 INPTSPTTATMANAN-RGPTSPSVTAIELIPSVTNPENLPSLPDIPPIQLEDAGSSSLDN 698
P+SPT + A + + SP I+L V NLPSLPDI + + + LDN
Sbjct: 552 STPSSPTITSAAGYDGKAFGSP---MIDLSSPVGGSYNLPSLPDI-----DCSSTIMLDN 603
Query: 699 LLSRYISGSHLPPQPTSTMN-PSPGPSALSPGSSG---LSNSHTPVRPPSTSSTGSRGSC 754
++ + + H P+P S SP S SPG +G +++ H P+R PS SS GSRGS
Sbjct: 604 IVRKDTNIDHGQPRPPSNRTVQSPNSSVPSPGLAGPVTMTSVHPPIRSPSASSVGSRGSS 663
Query: 755 GSSGRTAEKTSLS----FKSDQVKVKQEPGTEDEICSFSGG-VKQEKTEDGRRSACMLSS 809
GSS + A S + +++KQE E F VKQE E+ R
Sbjct: 664 GSSSKPAGADSTHKVPVVMLEPIRIKQENSGPPENYDFPVVIVKQESDEESR-------- 715
Query: 810 PESSLTP-PLSTNLHLESELDALASLENHVKIEPADMNESCKQSGLSSLVNGKSPIRSLM 868
P+++ P + T+L L S + S E ++ + D + NGKS
Sbjct: 716 PQNANYPRSILTSLLLNSS-QSSTSEETVLRSDAPDSTGDQPGLHQDNSSNGKSEWLDPS 774
Query: 869 HRSARIGGDGNNKDDDPNEDWCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPSGDWIC 928
+S G+ K+DDPNEDWCAVCQNGG+LLCCEKCPKVFHL+CHVPTL +FPSG+WIC
Sbjct: 775 QKSPLHVGE-TRKEDDPNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWIC 833
Query: 929 TFCRDIGKPEVEYDCDNLQHSKKGKTAQG---LSPVDQRKCERLLLYLYCHELSIEFQEP 985
TFCRD+ KPEVEYDCD H+ + K +G L+P+D+RKCERLLL+LYCHE+S+ FQ+P
Sbjct: 834 TFCRDLSKPEVEYDCDAPSHNSEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDP 893
Query: 986 VPASIPNYYKIIKKPMDLSTVKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFNEMMKVV 1045
VP ++P+YYKIIK PMDLST+KK+LQ+ +S Y P+DFVAD RLIF+NC FNE
Sbjct: 894 VPLTVPDYYKIIKNPMDLSTIKKRLQEDYSM-YSKPEDFVADFRLIFQNCAEFNE----- 947
Query: 1046 QVYADTQEINLKADSEVAQAGKAVALYFEDKLTEIYSDRTFAPLPEFEQEEDDGEVTEDS 1105
DSEVA AG + YFE+ L +Y ++ F P PEF E +D + ++DS
Sbjct: 948 ------------PDSEVANAGIKLENYFEELLKNLYPEKRF-PKPEFRNESEDNKFSDDS 994
Query: 1106 DEDFIQPRRKRLKSDE 1121
D+DF+QPR+KRLKS E
Sbjct: 995 DDDFVQPRKKRLKSIE 1010
>gi|5032179 tripartite motif-containing 28 protein [Homo sapiens]
Length = 835
Score = 340 bits (872), Expect = 4e-93
Identities = 178/436 (40%), Positives = 266/436 (61%), Gaps = 20/436 (4%)
Query: 68 AAASSGSAQAASSPAASVGTGVAGGAVSTPAPAPASAPAPGPSAGPPPGPPAS---LLDT 124
AAA+S +A +A+S + G G AGG + AP+ A++ + +A P G A LL+
Sbjct: 5 AAAASAAAASAASGSPGPGEGSAGGEKRSTAPSAAASASASAAASSPAGGGAEALELLEH 64
Query: 125 CAVCQQSLQSRREAEPKLLPCLHSFCLRCLPEPERQLSVPIPGGSNGDIQQVG---VIRC 181
C VC++ L R E EP+LLPCLHS C CL + P S+GD G V+ C
Sbjct: 65 CGVCRERL--RPEREPRLLPCLHSACSACLGP-----AAPAAANSSGDGGAAGDGTVVDC 117
Query: 182 PVCRQECRQIDLVDNYFVKDTSEAPSSSDEKSEQVCTSCEDNASAVGFCVECGEWLCKTC 241
PVC+Q+C D+V+NYF++D+ ++ + + Q CTSCEDNA A +CVEC E LC+TC
Sbjct: 118 PVCKQQCFSKDIVENYFMRDSGSKAATDAQDANQCCTSCEDNAPATSYCVECSEPLCETC 177
Query: 242 IEAHQRVKFTKDHLIRKKEDVSESVGASGQRPVFCPVHKQEQLKLFCETCDRLTCRDCQL 301
+EAHQRVK+TKDH +R + G+R V+C VHK E L LFCE+CD LTCRDCQL
Sbjct: 178 VEAHQRVKYTKDHTVRS---TGPAKSRDGERTVYCNVHKHEPLVLFCESCDTLTCRDCQL 234
Query: 302 LEHKEHRYQFLEEAFQNQKGAIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQE 361
HK+H+YQFLE+A +NQ+ + +L+ +L +K + + +V++ I++V++ KRV+ +
Sbjct: 235 NAHKDHQYQFLEDAVRNQRKLLASLVKRLGDKHATLQKSTKEVRSSIRQVSDVQKRVQVD 294
Query: 362 IKVAIFTLINEINKKGKSLLQQLENVTKERQMKLLQQQNDITGLSRQVKHVMNFTNWAIA 421
+K+AI ++ E+NK+G+ L+ + VT+ +Q +L +Q +T + + +H++ F +WA+
Sbjct: 295 VKMAILQIMKELNKRGRVLVNDAQKVTEGQQERLERQHWTMTKIQKHQEHILRFASWALE 354
Query: 422 SGSSTALLYSKRLITFQLRHILKARCDPVPAANGAIRFHCDPTFWAKNVVNLGNLVIESK 481
S ++TALL SK+LI FQL LK DPV +G ++F D W K+ G +V E
Sbjct: 355 SDNNTALLLSKKLIYFQLHRALKMIVDPV-EPHGEMKFQWDLNAWTKSAEAFGKIVAE-- 411
Query: 482 PAPGYTPNVVVGQVPP 497
PG PP
Sbjct: 412 -RPGTNSTGPAPMAPP 426
Score = 103 bits (256), Expect = 1e-21
Identities = 70/220 (31%), Positives = 104/220 (47%), Gaps = 28/220 (12%)
Query: 871 SARIGGDGNNKDDDPNEDWCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPSGDWICTF 930
SA GG G D + C VCQ GDL+ C +C FHL CH+P L P +W C+
Sbjct: 612 SAPGGGPGTLDD---SATICRVCQKPGDLVMCNQCEFCFHLDCHLPALQDVPGEEWSCSL 668
Query: 931 CRDIGKPEVEYDCDNLQHSKKGKTAQGLSPVDQRKCERLLLYLYCHELSIEFQEPVPASI 990
C + + E +L + LSP +QRKCER+LL L+CHE P+
Sbjct: 669 CHVLPDLKEEDGSLSLDGADSTGVVAKLSPANQRKCERVLLALFCHEPC----RPLHQLA 724
Query: 991 PNYYKIIKKP---MDLSTVKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFNEMMKVVQV 1047
+ + +P +DL+ ++ +LQ+K S Y P +F DV +FK +FN K+ +
Sbjct: 725 TDSTFSLDQPGGTLDLTLIRARLQEKLSPPYSSPQEFAQDVGRMFK---QFN---KLTED 778
Query: 1048 YADTQEINLKADSEVAQAGKAVALYFEDKLTEIYSDRTFA 1087
AD Q I + +FE ++ E + D F+
Sbjct: 779 KADVQSI------------IGLQRFFETRMNEAFGDTKFS 806
Score = 40.4 bits (93), Expect = 0.010
Identities = 34/116 (29%), Positives = 44/116 (37%), Gaps = 10/116 (8%)
Query: 18 GSAPVTAGAAG--PAAQEAEPPLTAVLVEEEEEEGGRAGAEGGAA-GPDDGGVAAASSGS 74
G+A G G PA PPL + + +EEE GA A GP+ V A +
Sbjct: 525 GAAAAATGQPGTAPAGTPGAPPLAGMAIVKEEETEAAIGAPPTATEGPETKPVLMALA-E 583
Query: 75 AQAASSPAASVGTGVAGGAVSTPAPAPASAPAPGPSAGPPPGPPASLLDTCAVCQQ 130
A P + +G + AP SAP G PG C VCQ+
Sbjct: 584 GPGAEGPRLASPSGSTSSGLEVVAPEGTSAPGGG------PGTLDDSATICRVCQK 633
>gi|209977097 tripartite motif-containing 66 [Homo sapiens]
Length = 1216
Score = 234 bits (596), Expect = 5e-61
Identities = 114/245 (46%), Positives = 162/245 (66%), Gaps = 33/245 (13%)
Query: 886 NEDWCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPSGDWICTFCRDIGKPEVEYDCDN 945
NED+CAVC NGG+LLCC++CPKVFHL+CHVP LLSFP G+W+CT CR + +PE+EYDC+N
Sbjct: 969 NEDFCAVCLNGGELLCCDRCPKVFHLSCHVPALLSFPGGEWVCTLCRSLTQPEMEYDCEN 1028
Query: 946 LQHSKKG-KTAQGLSPVDQRKCERLLLYLYCHELSIEFQEPVPASIPNYYKIIKKPMDLS 1004
+++ G + + GLS DQ+KCE+L+L L C+ LS+ F EPV +YY+IIK+PMDLS
Sbjct: 1029 ACYNQPGMRASPGLSMYDQKKCEKLVLSLCCNNLSLPFHEPVSPLARHYYQIIKRPMDLS 1088
Query: 1005 TVKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFNEMMKVVQVYADTQEINLKADSEVAQ 1064
+++KLQKK HY P++ V+DVRL+F NC +FN DSEVA+
Sbjct: 1089 IIRRKLQKKDPAHYTTPEEVVSDVRLMFWNCAKFN-----------------YPDSEVAE 1131
Query: 1065 AGKAVALYFEDKLTEIYSDRTFAPLPEFEQEEDDGEVTEDSD-------------EDFIQ 1111
AG+ + ++FE L EIY ++ FA +++ D EV+ +S ++ IQ
Sbjct: 1132 AGRCLEVFFEGWLKEIYPEKRFA--QPRQEDSDSEEVSSESGCSTPQGFPWPPYMQEGIQ 1189
Query: 1112 PRRKR 1116
P+R+R
Sbjct: 1190 PKRRR 1194
Score = 228 bits (582), Expect = 2e-59
Identities = 129/393 (32%), Positives = 199/393 (50%), Gaps = 39/393 (9%)
Query: 217 CTSCEDNASAVGFCVECGEWLCKTCIEAHQRVKFTKDHLIRKKEDVSESV-GASGQRPVF 275
C+ C++ +A C C WLC +C E H+ + + S V G G ++
Sbjct: 5 CSECKEKRAAHILCTYCNRWLCSSCTEEHRHSPVPGGPFFPRAQKGSPGVNGGPGDFTLY 64
Query: 276 CPVHKQEQLKLFCETCDRLTCRDCQLLEHKEHRYQFLEEAFQNQKGAIENLLAKLLEKKN 335
CP+H QE LKLFCETCD LTC C ++EHKEHR + +EE QNQ+ +E + ++ KK+
Sbjct: 65 CPLHTQEVLKLFCETCDMLTCHSCLVVEHKEHRCRHVEEVLQNQRMLLEGVTTQVAHKKS 124
Query: 336 YVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLINEINKKGKSLLQQLENVTKERQMKL 395
+ +A Q+++RI EV +++VE +IK+A L+NE+NK+ L+++LE +T ER+ KL
Sbjct: 125 SLQTSAKQIEDRIFEVKHQHRKVENQIKMAKMVLMNELNKQANGLIEELEGITNERKRKL 184
Query: 396 LQQQNDITGLSRQVKHVMNFTNWAIASGSSTALLYSKRLITFQLRHILKARCDPVPAANG 455
QQ I L+RQ +HV NF NWA+ S +S L+SK LI FQ++ +L+ C+ P +
Sbjct: 185 EQQLQSIMVLNRQFEHVQNFINWAVCSKTSVPFLFSKELIVFQMQRLLETSCNTDPGSPW 244
Query: 456 AIRFHCDPTFWAKNVVNLGNLVIES-----KPAPGYTPNVVVGQVPPGTNHISKTPGQIN 510
+IRF +P FW K + +LG + E AP Y + G P +H S
Sbjct: 245 SIRFTWEPNFWTKQLASLGCITTEGGQMSRADAPAY--GGLQGSSPFYQSHQSPV----- 297
Query: 511 LAQLRLQHMQQQVYAQKHQQLQQMRMQQPPAPVPTTTTTTQQHPRQAAPQMLQQQPPRLI 570
QQ+ + + Q +P +++ H +P + Q PP I
Sbjct: 298 --------AQQEALSHPSHKFQ--------SPAVCSSSVCCSHCSPVSPSLKGQVPPPSI 341
Query: 571 ----------SVQTMQRGNMNCGAFQAHQMRLA 593
+ Q G++ C A + LA
Sbjct: 342 HPAHSFRQPPEMVPQQLGSLQCSALLPREKELA 374
Score = 40.8 bits (94), Expect = 0.007
Identities = 77/347 (22%), Positives = 132/347 (38%), Gaps = 67/347 (19%)
Query: 513 QLRLQHMQQQVYAQKHQQLQQMRMQQPPAPVPTTTTTTQQHP---RQAAPQMLQQQPPRL 569
+ L+ MQ+ + Q +++ Q +P T Q RQ AP Q Q L
Sbjct: 511 KFELEEMQKDLELLLQAQQPSLQLSQTKSPQHLQQTIVGQINYIVRQPAPVQSQSQEETL 570
Query: 570 ISVQTMQRGNMNCGAFQAHQMRLAQNAARIPGIPRHSGPQYSMMQPHLQR--QHSNPGHA 627
+ A Q + L + +P+ SG + + P + QHS+P
Sbjct: 571 QATDEPP-------ASQGSKPALPLDKNTAAALPQASGEETPLSVPPVDSTIQHSSPN-- 621
Query: 628 GPFPVVSVHNTTINPTS-PTTATMANANRGPTSPSVTAIELIPSVTN--PENLPSLPDIP 684
VV H+T+++ T M ++ P I+ + ++T P+ +PSL P
Sbjct: 622 ----VVRKHSTSLSIMGFSNTLEMELSSTRLERPLEPQIQSVSNLTAGAPQAVPSLLSAP 677
Query: 685 PIQLEDAGSSSLDNLLSRYISGSHLPPQPT-----------------------STMNPSP 721
P + +S+ N ++ SHL P+ ++ +P
Sbjct: 678 PKMVSSL--TSVQNQAMPSLTTSHLQTVPSLVHSTFQSMPNLISDSPQAMASLASDHPQA 735
Query: 722 GPSALSPGSSGLSNSHT-PVR--PPSTSSTGSRGSCGSSGRTAEKTSLSFKSDQVKVKQE 778
GPS +S + + + T P++ PP + GS SSGRT+ +D
Sbjct: 736 GPSLMSGHTQAVPSLATCPLQSIPPVSDMQPETGSSSSSGRTSGSLCPRDGAD------- 788
Query: 779 PGTEDEICSFSGGVKQEKTEDGRRSACMLSSPESSLTPPLSTNLHLE 825
P E+ +C VK E+ + LS + L P +ST+ L+
Sbjct: 789 PSLENALCK----VKLEEPIN-------LSVKKPPLAPVVSTSTALQ 824
>gi|224548923 tripartite motif-containing 45 isoform 2 [Homo
sapiens]
Length = 562
Score = 140 bits (352), Expect = 9e-33
Identities = 102/346 (29%), Positives = 154/346 (44%), Gaps = 36/346 (10%)
Query: 140 PKLLPCLHSFCLRCLPEPERQLSVPIPGG-----SNGDI----------QQVGVIRCPVC 184
P+LLPCLH+ C CL + E V I GG S G I Q+G++ CPVC
Sbjct: 39 PRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQSQIGIL-CPVC 97
Query: 185 RQECRQIDL---------VDNYFVKDTSEAPSSSDEKSEQVCTSCEDNASAVGFCVECGE 235
Q+DL +D+ V D S E VC C D C C
Sbjct: 98 DA---QVDLPMGGVKALTIDHLAVNDVM-LESLRGEGQGLVCDLCNDR-EVEKRCQTCKA 152
Query: 236 WLCKTCIEAHQRVKFTKDHLIRKKEDVS--ESVGASGQRPVFCPVHKQEQLKLFCETCDR 293
LC C +AH+R K T H + +D+ +G +P+ CPVH E+L+LFCE CDR
Sbjct: 153 NLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSRIG----KPILCPVHPAEELRLFCEFCDR 208
Query: 294 LTCRDCQLLEHKEHRYQFLEEAFQNQKGAIENLLAKLLEKKNYVHFAATQVQNRIKEVNE 353
C+DC + EH+EH F ++ LL + A Q+ + +
Sbjct: 209 PVCQDCVVGEHREHPCDFTSNVIHKHGDSVWELLKGTQPHVEALEEALAQIHIINSALQK 268
Query: 354 TNKRVEQEIKVAIFTLINEINKKGKSLLQQLENVTKERQMKLLQQQNDITGLSRQVKHVM 413
+ V +++ I I + LL+QLE++ +++ L Q+ + L ++ +
Sbjct: 269 RVEAVAADVRTFSEGYIKAIEEHRDKLLKQLEDIRAQKENSLQLQKAQLEQLLADMRTGV 328
Query: 414 NFTNWAIASGSSTALLYSKRLITFQLRHILKARCDPVPAANGAIRF 459
FT + SGS +L +KR++ +LR + K + P N IRF
Sbjct: 329 EFTEHLLTSGSDLEILITKRVVVERLRKLNKVQYSTRPGVNDKIRF 374
>gi|224548921 tripartite motif-containing 45 isoform 1 [Homo
sapiens]
Length = 580
Score = 140 bits (352), Expect = 9e-33
Identities = 102/346 (29%), Positives = 154/346 (44%), Gaps = 36/346 (10%)
Query: 140 PKLLPCLHSFCLRCLPEPERQLSVPIPGG-----SNGDI----------QQVGVIRCPVC 184
P+LLPCLH+ C CL + E V I GG S G I Q+G++ CPVC
Sbjct: 39 PRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQSQIGIL-CPVC 97
Query: 185 RQECRQIDL---------VDNYFVKDTSEAPSSSDEKSEQVCTSCEDNASAVGFCVECGE 235
Q+DL +D+ V D S E VC C D C C
Sbjct: 98 DA---QVDLPMGGVKALTIDHLAVNDVM-LESLRGEGQGLVCDLCNDR-EVEKRCQTCKA 152
Query: 236 WLCKTCIEAHQRVKFTKDHLIRKKEDVS--ESVGASGQRPVFCPVHKQEQLKLFCETCDR 293
LC C +AH+R K T H + +D+ +G +P+ CPVH E+L+LFCE CDR
Sbjct: 153 NLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSRIG----KPILCPVHPAEELRLFCEFCDR 208
Query: 294 LTCRDCQLLEHKEHRYQFLEEAFQNQKGAIENLLAKLLEKKNYVHFAATQVQNRIKEVNE 353
C+DC + EH+EH F ++ LL + A Q+ + +
Sbjct: 209 PVCQDCVVGEHREHPCDFTSNVIHKHGDSVWELLKGTQPHVEALEEALAQIHIINSALQK 268
Query: 354 TNKRVEQEIKVAIFTLINEINKKGKSLLQQLENVTKERQMKLLQQQNDITGLSRQVKHVM 413
+ V +++ I I + LL+QLE++ +++ L Q+ + L ++ +
Sbjct: 269 RVEAVAADVRTFSEGYIKAIEEHRDKLLKQLEDIRAQKENSLQLQKAQLEQLLADMRTGV 328
Query: 414 NFTNWAIASGSSTALLYSKRLITFQLRHILKARCDPVPAANGAIRF 459
FT + SGS +L +KR++ +LR + K + P N IRF
Sbjct: 329 EFTEHLLTSGSDLEILITKRVVVERLRKLNKVQYSTRPGVNDKIRF 374
>gi|84993742 tripartite motif-containing 71 [Homo sapiens]
Length = 868
Score = 104 bits (259), Expect = 5e-22
Identities = 100/450 (22%), Positives = 169/450 (37%), Gaps = 56/450 (12%)
Query: 58 GAAGPDDGGVAAASSGSAQAASSPAASVGTGVAGG---------AVSTPAPAPASAPAPG 108
G+ P +A+SS S + SS G G A A P PA G
Sbjct: 20 GSPAPLSSNSSASSSSSQTSTSSGGGGGGPGAAARRLHVLPCLHAFCRPCLEAHRLPAAG 79
Query: 109 PSAGPPPGPPASLLDTCAVCQQSLQSRREAEPKLLPCLHSFCLRCLPE---------PER 159
A G P L C VC Q + A LP +F L L + P +
Sbjct: 80 GGAA---GEPLKL--RCPVCDQKVVLAEAAGMDALPS-SAFLLSNLLDAVVATADEPPPK 133
Query: 160 QLSVPIPGGSNGDIQ----------QVGVIRCPVCRQECRQIDLVDNYFVKDTSEAPSSS 209
P G+ G + P+ + Q + +PS+
Sbjct: 134 NGRAGAPAGAGGHSNHRHHAHHAHPRASASAPPL--PQAPQPPAPSRSAPGGPAASPSAL 191
Query: 210 DEKSEQVCTSCEDNASAVGFCVECGEWLCKTCIEAHQRVKFTKDHLIRKKEDVSESVGAS 269
+ C+SC++ +A C++C E LC C+ AHQRV+ TKDH I + + A+
Sbjct: 192 LLRRPHGCSSCDEGNAASSRCLDCQEHLCDNCVRAHQRVRLTKDHYIERGPPGPGAAAAA 251
Query: 270 GQ--------------------RPVFCPVHKQEQLKLFCETCDRLTCRDCQLLEHKEHRY 309
Q R FC H E L L+C+TC CR+C + H H +
Sbjct: 252 QQLGLGPPFPGPPFSILSVFPERLGFCQHHDDEVLHLYCDTCSVPICRECTMGRHGGHSF 311
Query: 310 QFLEEAFQNQKGAIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTL 369
+L+EA Q+ + LLA + + + + Q Q ++V K V+ E+K
Sbjct: 312 IYLQEALQDSRALTIQLLADAQQGRQAIQLSIEQAQTVAEQVEMKAKVVQSEVKAVTARH 371
Query: 370 INEINKKGKSLLQQLENVTKERQMKLLQQQNDITGLSRQVKHVMNFTNWAIASGSSTALL 429
+ ++ LL ++E + + + L Q + +++ ++ + G + +L
Sbjct: 372 KKALEERECELLWKVEKIRQVKAKSLYLQVEKLRQNLNKLESTISAVQQVLEEGRALDIL 431
Query: 430 YSKRLITFQLRHILKARCDPVPAANGAIRF 459
++ + Q++ + R P + + F
Sbjct: 432 LARDRMLAQVQELKTVRSLLQPQEDDRVMF 461
Score = 37.7 bits (86), Expect = 0.062
Identities = 44/174 (25%), Positives = 63/174 (36%), Gaps = 47/174 (27%)
Query: 12 SGGGGSGSAP------------VTAGAAGPAAQEAEPPLTAVLVE-------EEEEEGGR 52
+ GGG+ P V A AAG A + L + L++ E + GR
Sbjct: 77 AAGGGAAGEPLKLRCPVCDQKVVLAEAAGMDALPSSAFLLSNLLDAVVATADEPPPKNGR 136
Query: 53 AGAEGGAAGPDDGGVAAASSGSAQAASSPAASVGTGVAGGAVSTPAPAPASAPAPGPSAG 112
AGA GA G + A + +AS+P P P + P PS
Sbjct: 137 AGAPAGAGGHSNHRHHAHHAHPRASASAP-----------------PLPQAPQPPAPSRS 179
Query: 113 PPPGP---PASLL----DTCAVCQQSLQSRREAEPKLLPCLHSFCLRCLPEPER 159
P GP P++LL C+ C + A + L C C C+ +R
Sbjct: 180 APGGPAASPSALLLRRPHGCSSCDEG----NAASSRCLDCQEHLCDNCVRAHQR 229
>gi|134133279 SP140 nuclear body protein-like [Homo sapiens]
Length = 580
Score = 103 bits (257), Expect = 9e-22
Identities = 90/296 (30%), Positives = 131/296 (44%), Gaps = 49/296 (16%)
Query: 790 GGVK----QEKTEDGRRSACMLSSPESSLTPPLSTNLHLESELDALASLENHVKIEPADM 845
GGVK +EK E G + C+ + TP +E E+ + + + +
Sbjct: 308 GGVKGILHKEKLEQGTLAKCIQTEDGKWFTP-------MEFEIKG-----GYARSKNWRL 355
Query: 846 NESCKQSGLSSLVNGKS---PIRSLMHRSARIGGDGNNKDDDP---NEDWCAVCQNGGDL 899
+ C L L+ S P R RI NN DP N D C VC++GG+L
Sbjct: 356 SVRCGGWPLRRLMEEGSLPNPPRIYYRNKKRILKSQNNSSVDPCMRNLDECEVCRDGGEL 415
Query: 900 LCCEKCPKVFHLTCHVPTLLSFPSGDWICTFCRDIGKPEVEYDCDNLQHSKKGKTAQGLS 959
CC+ C +VFH CH+P + S W C FCR P + C + ++ +
Sbjct: 416 FCCDTCSRVFHEDCHIPPVES-EKTPWNCIFCRMKESPGSQQCCQESEVLER-----QMC 469
Query: 960 PVDQRKCERLLLYLYCHELSIEFQEPVPASIPNYYKI------IKKPMDLSTVKKKLQKK 1013
P +Q KCE LLL +YC S F A IP YY I +K+PM L +KK+L
Sbjct: 470 PEEQLKCEFLLLKVYCCSESSFF-----AKIPYYYYIREACQGLKEPMWLDKIKKRL--- 521
Query: 1014 HSQHYQIPDDFVADVRLIFKNCERFNEMMKVVQVYADTQEINLKADSEVAQAGKAV 1069
+ Y + FV D+RLIF+N + Y D ++ L+ ++E + K V
Sbjct: 522 NEHGYPQVEGFVQDMRLIFQN-------HRASYKYKDFGQMGLRLEAEFEKDFKEV 570
>gi|217330601 SP140 nuclear body protein isoform 1 [Homo sapiens]
Length = 867
Score = 99.4 bits (246), Expect = 2e-20
Identities = 66/181 (36%), Positives = 89/181 (49%), Gaps = 23/181 (12%)
Query: 863 PIRSLMHRSARIGGDGNNKDDDP---NEDWCAVCQNGGDLLCCEKCPKVFHLTCHVPTLL 919
P R + RI NN DP N D C VC++GG+L CC+ C +VFH CH+P +
Sbjct: 663 PPRIRYRKKKRILKSQNNSSVDPCMRNLDECEVCRDGGELFCCDTCSRVFHEDCHIPP-V 721
Query: 920 SFPSGDWICTFCRDIGKPEVEYDCDNLQHSKKGKTAQGLSPVDQRKCERLLLYLYCHELS 979
W C FCR P + C + ++ + P +Q KCE LLL +YC S
Sbjct: 722 EAERTPWNCIFCRMKESPGSQQCCQESEVLER-----QMCPEEQLKCEFLLLKVYCCSES 776
Query: 980 IEFQEPVPASIPNYYKI------IKKPMDLSTVKKKLQKKHSQHYQIPDDFVADVRLIFK 1033
F A IP YY I +K+PM L +KK+L + Y + FV D+RLIF+
Sbjct: 777 SFF-----AKIPYYYYIREACQGLKEPMWLDKIKKRL---NEHGYPQVEGFVQDMRLIFQ 828
Query: 1034 N 1034
N
Sbjct: 829 N 829
>gi|30794216 tripartite motif-containing 56 [Homo sapiens]
Length = 755
Score = 96.7 bits (239), Expect = 1e-19
Identities = 79/348 (22%), Positives = 143/348 (41%), Gaps = 43/348 (12%)
Query: 125 CAVCQQSLQSRREAEPKLLPCLHSFCLRCLPEPERQLSVPIPGGSNGDIQQVGVIRCPVC 184
C +C + L++ PK LPCLH++C CL + + G +RCP C
Sbjct: 21 CKICLEQLRA-----PKTLPCLHTYCQDCLAQ----------------LADGGRVRCPEC 59
Query: 185 RQECRQ-----IDLVDNYFVK---DTSEAPSSSDEKS-EQVCTSC------EDNASAVGF 229
R+ N+FV D +A + D ++ + C C A
Sbjct: 60 RETVPVPPEGVASFKTNFFVNGLLDLVKARACGDLRAGKPACALCPLVGGTSTGGPATAR 119
Query: 230 CVECGEWLCKTCIEAHQRVKFTKDHLIRKKEDVSESVG-----ASGQRPVFCPVHKQEQL 284
C++C + LC+ C + H+ + T H R + V G A ++ CP H E L
Sbjct: 120 CLDCADDLCQACADGHRCTRQTHTH--RVVDLVGYRAGWYDEEARERQAAQCPQHPGEAL 177
Query: 285 KLFCETCDRLTCRDCQLLEHKEHRYQFLEEAFQNQKGAIENLLAKLLEKKNYVHFAATQV 344
+ C+ C +L CR+C+L H +H L EA + ++ +E LLA + + A
Sbjct: 178 RFLCQPCSQLLCRECRLDPHLDHPCLPLAEAVRARRPGLEGLLAGVDNNLVELEAARRVE 237
Query: 345 QNRIKEVNETNKRVEQEIKVAIFTLINEINKKGKSLLQQLENVTKERQMKLLQQQNDITG 404
+ + + E RV +++ A ++ + + + +L QL + + ++ ++ G
Sbjct: 238 KEALARLREQAARVGTQVEEAAEGVLRALLAQKQEVLGQLRAHVEAAEEAARERLAELEG 297
Query: 405 LSRQVKHVMNFTNWAIASGSSTALLYSKRLITFQLRHILKARCDPVPA 452
+ + F ++ G +L + I +LR + P PA
Sbjct: 298 REQVARAAAAFARRVLSLGREAEILSLEGAIAQRLRQLQGCPWAPGPA 345
>gi|122939208 nuclear antigen Sp100 isoform 1 [Homo sapiens]
Length = 885
Score = 94.4 bits (233), Expect = 6e-19
Identities = 90/297 (30%), Positives = 124/297 (41%), Gaps = 38/297 (12%)
Query: 769 KSDQVKVKQE--PGTEDEICSFSGGVKQEKTEDGRRSACMLSSPESSLTPPLSTNLHLES 826
K + + KQ P T E+ G + +E+ + G C+ S + TP E
Sbjct: 594 KDENINFKQSELPVTCGEV---KGTLYKERFKQGTSKKCIQSEDKKWFTPR-----EFEI 645
Query: 827 ELDALASLENHVKIEPADMNESCKQSGLSSLVNGKSPIRSLMHRSARIGGDGNNKDDDP- 885
E D AS + I C L L+ K R RI NN DP
Sbjct: 646 EGDRGASKNWKLSIR-------CGGYTLKVLMENKFLPEPPSTRKKRILESHNNTLVDPC 698
Query: 886 --NEDWCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPSGDWICTFCRDIGKPEVEYDC 943
N + C VC G L CC+ CP+ FH CH+P+ + W C FCR ++ C
Sbjct: 699 PENSNICEVCNKWGRLFCCDTCPRSFHEHCHIPS-VEANKNPWSCIFCR---IKTIQERC 754
Query: 944 DNLQ--HSKKGKTAQGLSPVDQRKCERLLLYLYCHELSIEFQEPVPASIPNYYKI----I 997
Q H + + + P +Q KCE LLL +YC S F AS P Y +
Sbjct: 755 PESQSGHQESEVLMRQMLPEEQLKCEFLLLKVYCDSKSCFF-----ASEPYYNREGSQGP 809
Query: 998 KKPMDLSTVKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFNEMMKVVQVYADTQEI 1054
+KPM L+ VK L + Q Y + FV D+RLIF N + F K ++ Q+I
Sbjct: 810 QKPMWLNKVKTSL---NEQMYTRVEGFVQDMRLIFHNHKEFYREDKFTRLGIQVQDI 863
>gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo
sapiens]
Length = 1905
Score = 93.2 bits (230), Expect = 1e-18
Identities = 70/247 (28%), Positives = 108/247 (43%), Gaps = 68/247 (27%)
Query: 886 NEDWCAVCQNGGD---LLCCEKCPKVFHLTCHVPTLLSFPSGDWICTFC----------R 932
N+ C VC+ G + LL C+ C + H+ CH P + + P GDW CT C +
Sbjct: 1675 NKVTCLVCRKGDNDEFLLLCDGCDRGCHIYCHRPKMEAVPEGDWFCTVCLAQQVEGEFTQ 1734
Query: 933 DIGKPE-------------VEYDCDNLQHSKKGKTA---------QGLSPVDQRK----- 965
G P+ E D + +G+ + +GLSP +R+
Sbjct: 1735 KPGFPKRGQKRKSGYSLNFSEGDGRRRRVLLRGRESPAAGPRYSEEGLSPSKRRRLSMRN 1794
Query: 966 -------CERLLLYLYCHELSIEFQEPV-PASIPNYYKIIKKPMDLSTVKKKLQKKHSQH 1017
CE +L+ + H+ + F EPV P + Y +IIK PMD ST++++L +
Sbjct: 1795 HHSDLTFCEIILMEMESHDAAWPFLEPVNPRLVSGYRRIIKNPMDFSTMRERLLRGG--- 1851
Query: 1018 YQIPDDFVADVRLIFKNCERFNEMMKVVQVYADTQEINLKADSEVAQAGKAVALYFEDKL 1077
Y ++F AD L+F NC+ FNE DSEV +AG + +FE +
Sbjct: 1852 YTSSEEFAADALLVFDNCQTFNE-----------------DDSEVGKAGHIMRRFFESRW 1894
Query: 1078 TEIYSDR 1084
E Y +
Sbjct: 1895 EEFYQGK 1901
>gi|190343006 SP110 nuclear body protein isoform c [Homo sapiens]
Length = 713
Score = 93.2 bits (230), Expect = 1e-18
Identities = 61/167 (36%), Positives = 85/167 (50%), Gaps = 11/167 (6%)
Query: 886 NEDWCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPSGDWICTFCRDIGKPEVEYDCDN 945
N D C VC GG LLCC CP+VFH CH+P + W CTFCR + + C
Sbjct: 533 NSDECEVCCQGGQLLCCGTCPRVFHEDCHIPP-VEAKRMLWSCTFCR-MKRSSGSQQC-- 588
Query: 946 LQHSKKGKTAQGLSPVDQRKCERLLLYLYCHELSIEFQEPVPASIPNYYKIIKKPMDLST 1005
H + + P DQ KCE LLL YCH S F +P +I +Y + ++ M L
Sbjct: 589 --HHVSKTLERQMQPQDQLKCEFLLLKAYCHPQS-SFFTGIPFNIRDYGEPFQEAMWLDL 645
Query: 1006 VKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFNEMMKVVQVYADTQ 1052
VK++L ++ Y + FV D+RL+F+N + F + QV D +
Sbjct: 646 VKERL---ITEMYTVA-WFVRDMRLMFRNHKTFYKASDFGQVGLDLE 688
>gi|32454739 tripartite motif-containing 3 [Homo sapiens]
Length = 744
Score = 91.3 bits (225), Expect = 5e-18
Identities = 86/373 (23%), Positives = 150/373 (40%), Gaps = 62/373 (16%)
Query: 115 PGPPASLLD----TCAVCQQSLQSRREAEPKLLPCLHSFCLRCLPEPERQLSVPIPGGSN 170
PGP +D C++C Q PK+LPCLH+FC RCL Q +P
Sbjct: 8 PGPEVQPMDKQFLVCSICLDRYQC-----PKVLPCLHTFCERCL-----QNYIPA----- 52
Query: 171 GDIQQVGVIRCPVCRQECRQIDLVDNYFVKDTSEAPSSSDEKSEQVCTSCEDNASAVGFC 230
Q + CPVCRQ TS P EQ ++ ++N
Sbjct: 53 ----QSLTLSCPVCRQ---------------TSILP-------EQGVSALQNN------- 79
Query: 231 VECGEWLCKTCIEAHQRVKFTKDHLIRKKEDVSESVGASGQRPVFCPVHKQEQLKLFCET 290
+ + +EA Q+ D ++ SV A RP+ CP H+ + ++ +CE
Sbjct: 80 -----FFISSLMEAMQQAP---DGAHDPEDPHPLSVVAG--RPLSCPNHEGKTMEFYCEA 129
Query: 291 CDRLTCRDCQLLEHKEHRYQFLEEAFQNQKGAIENLLAKLLEKKNYVHFAATQVQNRIKE 350
C+ C +C+ EH+EH L + + K A++ L + + + A V ++
Sbjct: 130 CETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAIALVGGISQQ 189
Query: 351 VNETNKRVEQEIKVAIFTLINEINKKGKSLLQQLENVTKERQMKLLQQQNDITGLSRQVK 410
+ E +I A L + ++ ++L+ LE + +Q L Q + + +
Sbjct: 190 LQERKAEALAQISAAFEDLEQALQQRKQALVSDLETICGAKQKVLQSQLDTLRQGQEHIG 249
Query: 411 HVMNFTNWAIASGSSTALLYSKRLITFQLRHILKARCDPVPAANGAIRFHCDPTFWAKNV 470
+F A+ GS+ +L ++ + +L + P N + + ++V
Sbjct: 250 SSCSFAEQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQLELVLEVDGLRRSV 309
Query: 471 VNLGNLVIESKPA 483
+NLG L+ S A
Sbjct: 310 LNLGALLTTSATA 322
>gi|32454737 tripartite motif-containing 3 [Homo sapiens]
Length = 744
Score = 91.3 bits (225), Expect = 5e-18
Identities = 86/373 (23%), Positives = 150/373 (40%), Gaps = 62/373 (16%)
Query: 115 PGPPASLLD----TCAVCQQSLQSRREAEPKLLPCLHSFCLRCLPEPERQLSVPIPGGSN 170
PGP +D C++C Q PK+LPCLH+FC RCL Q +P
Sbjct: 8 PGPEVQPMDKQFLVCSICLDRYQC-----PKVLPCLHTFCERCL-----QNYIPA----- 52
Query: 171 GDIQQVGVIRCPVCRQECRQIDLVDNYFVKDTSEAPSSSDEKSEQVCTSCEDNASAVGFC 230
Q + CPVCRQ TS P EQ ++ ++N
Sbjct: 53 ----QSLTLSCPVCRQ---------------TSILP-------EQGVSALQNN------- 79
Query: 231 VECGEWLCKTCIEAHQRVKFTKDHLIRKKEDVSESVGASGQRPVFCPVHKQEQLKLFCET 290
+ + +EA Q+ D ++ SV A RP+ CP H+ + ++ +CE
Sbjct: 80 -----FFISSLMEAMQQAP---DGAHDPEDPHPLSVVAG--RPLSCPNHEGKTMEFYCEA 129
Query: 291 CDRLTCRDCQLLEHKEHRYQFLEEAFQNQKGAIENLLAKLLEKKNYVHFAATQVQNRIKE 350
C+ C +C+ EH+EH L + + K A++ L + + + A V ++
Sbjct: 130 CETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAIALVGGISQQ 189
Query: 351 VNETNKRVEQEIKVAIFTLINEINKKGKSLLQQLENVTKERQMKLLQQQNDITGLSRQVK 410
+ E +I A L + ++ ++L+ LE + +Q L Q + + +
Sbjct: 190 LQERKAEALAQISAAFEDLEQALQQRKQALVSDLETICGAKQKVLQSQLDTLRQGQEHIG 249
Query: 411 HVMNFTNWAIASGSSTALLYSKRLITFQLRHILKARCDPVPAANGAIRFHCDPTFWAKNV 470
+F A+ GS+ +L ++ + +L + P N + + ++V
Sbjct: 250 SSCSFAEQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQLELVLEVDGLRRSV 309
Query: 471 VNLGNLVIESKPA 483
+NLG L+ S A
Sbjct: 310 LNLGALLTTSATA 322
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 89.4 bits (220), Expect = 2e-17
Identities = 69/253 (27%), Positives = 99/253 (39%), Gaps = 80/253 (31%)
Query: 889 WCAVCQNGGD---LLCCEKCPKVFHLTCHVPTLLSFPSGDWICTFC------RDIGKPEV 939
+C +C+ G + LL C+ C K H CH P + + P GDW C C + + ++
Sbjct: 1933 YCQICRKGDNEELLLLCDGCDKGCHTYCHRPKITTIPDGDWFCPACIAKASGQTLKIKKL 1992
Query: 940 EYDCDNLQHSKKGKTA-------------------QGLSPVDQRK--------------- 965
SKKGK +G + +RK
Sbjct: 1993 HVKGKKTNESKKGKKVTLTGDTEDEDSASTSSSLKRGNKDLKKRKMEENTSINLSKQESF 2052
Query: 966 ----------------CERLLLYLYCHELSIEFQEPVPAS-IPNYYKIIKKPMDLSTVKK 1008
C +L + HE + F PV +P Y K+IKKPMD ST+++
Sbjct: 2053 TSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIRE 2112
Query: 1009 KLQKKHSQHYQIPDDFVADVRLIFKNCERFNEMMKVVQVYADTQEINLKADSEVAQAGKA 1068
KL S Y + F DVRL+F NCE FNE DS++ +AG
Sbjct: 2113 KLS---SGQYPNLETFALDVRLVFDNCETFNE-----------------DDSDIGRAGHN 2152
Query: 1069 VALYFEDKLTEIY 1081
+ YFE K T+ +
Sbjct: 2153 MRKYFEKKWTDTF 2165
>gi|194248079 tripartite motif-containing 2 isoform 1 [Homo sapiens]
Length = 771
Score = 86.7 bits (213), Expect = 1e-16
Identities = 93/399 (23%), Positives = 156/399 (39%), Gaps = 93/399 (23%)
Query: 106 APGPSAGPP-------------PGPPASLLDT----CAVCQQSLQSRREAEPKLLPCLHS 148
A +AGPP P P +D C++C + R PK+LPCLH+
Sbjct: 14 AGSKTAGPPCQWSRMASEGTNIPSPVVRQIDKQFLICSICLE-----RYKNPKVLPCLHT 68
Query: 149 FCLRCLPEPERQLSVPIPGGSNGDIQQVGVIRCPVCRQ-----ECRQIDLVDNYFVKDTS 203
FC RCL IP S + CPVCRQ E L +N+F+ +
Sbjct: 69 FCERCLQNY-------IPAHSL-------TLSCPVCRQTSILPEKGVAALQNNFFITNLM 114
Query: 204 EA----PSSSDEKSEQVCTSCEDNASAVGFCVECGEWLCKTCIEAHQRVKFTKDHLIRKK 259
+ P S+ E+S S + +AV
Sbjct: 115 DVLQRTPGSNAEES-----SILETVTAV-------------------------------- 137
Query: 260 EDVSESVGASGQRPVFCPVHKQEQLKLFCETCDRLTCRDCQLLEHKEHRYQFLEEAFQNQ 319
A+G +P+ CP H ++ +C++C+ CR+C EH EH L++ +
Sbjct: 138 --------AAG-KPLSCPNHDGNVMEFYCQSCETAMCRECTEGEHAEHPTVPLKDVVEQH 188
Query: 320 KGAIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLINEINKKGKS 379
K +++ L + ++ + A + I ++ + +I L +N +
Sbjct: 189 KASLQVQLDAVNKRLPEIDSALQFISEIIHQLTNQKASIVDDIHSTFDELQKTLNVRKSV 248
Query: 380 LLQQLENVTKERQMKLLQQQND-ITGLSRQVKHVMNFTNWAIASGSSTALLYSKRLITFQ 438
LL +LE V + K+LQ Q D + +K NFT A+ G+ T +L K+ ++ +
Sbjct: 249 LLMELE-VNYGLKHKVLQSQLDTLLQGQESIKSCSNFTAQALNHGTETEVLLVKKQMSEK 307
Query: 439 LRHILKARCDPVPAANGAIRFHCDPTFWAKNVVNLGNLV 477
L + P N + F + K++ NLG ++
Sbjct: 308 LNELADQDFPLHPRENDQLDFIVETEGLKKSIHNLGTIL 346
>gi|194248081 tripartite motif-containing 2 isoform 2 [Homo sapiens]
Length = 744
Score = 85.9 bits (211), Expect = 2e-16
Identities = 88/377 (23%), Positives = 150/377 (39%), Gaps = 80/377 (21%)
Query: 115 PGPPASLLDT----CAVCQQSLQSRREAEPKLLPCLHSFCLRCLPEPERQLSVPIPGGSN 170
P P +D C++C + R PK+LPCLH+FC RCL IP S
Sbjct: 9 PSPVVRQIDKQFLICSICLE-----RYKNPKVLPCLHTFCERCLQNY-------IPAHSL 56
Query: 171 GDIQQVGVIRCPVCRQ-----ECRQIDLVDNYFVKDTSEA----PSSSDEKSEQVCTSCE 221
+ CPVCRQ E L +N+F+ + + P S+ E+S S
Sbjct: 57 -------TLSCPVCRQTSILPEKGVAALQNNFFITNLMDVLQRTPGSNAEES-----SIL 104
Query: 222 DNASAVGFCVECGEWLCKTCIEAHQRVKFTKDHLIRKKEDVSESVGASGQRPVFCPVHKQ 281
+ +AV A+G +P+ CP H
Sbjct: 105 ETVTAV----------------------------------------AAG-KPLSCPNHDG 123
Query: 282 EQLKLFCETCDRLTCRDCQLLEHKEHRYQFLEEAFQNQKGAIENLLAKLLEKKNYVHFAA 341
++ +C++C+ CR+C EH EH L++ + K +++ L + ++ + A
Sbjct: 124 NVMEFYCQSCETAMCRECTEGEHAEHPTVPLKDVVEQHKASLQVQLDAVNKRLPEIDSAL 183
Query: 342 TQVQNRIKEVNETNKRVEQEIKVAIFTLINEINKKGKSLLQQLENVTKERQMKLLQQQND 401
+ I ++ + +I L +N + LL +LE V + K+LQ Q D
Sbjct: 184 QFISEIIHQLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELE-VNYGLKHKVLQSQLD 242
Query: 402 -ITGLSRQVKHVMNFTNWAIASGSSTALLYSKRLITFQLRHILKARCDPVPAANGAIRFH 460
+ +K NFT A+ G+ T +L K+ ++ +L + P N + F
Sbjct: 243 TLLQGQESIKSCSNFTAQALNHGTETEVLLVKKQMSEKLNELADQDFPLHPRENDQLDFI 302
Query: 461 CDPTFWAKNVVNLGNLV 477
+ K++ NLG ++
Sbjct: 303 VETEGLKKSIHNLGTIL 319
>gi|148833499 midline 1 [Homo sapiens]
Length = 667
Score = 84.0 bits (206), Expect = 8e-16
Identities = 86/354 (24%), Positives = 146/354 (41%), Gaps = 72/354 (20%)
Query: 124 TCAVCQQSLQSRREAEPKLLPCLHSFCLRCLPEPERQLSVPIPGGSNGDIQQVGVIRCPV 183
TC +C + + +P LLPC HS C C + +N ++ + +CP
Sbjct: 9 TCPICLELFE-----DPLLLPCAHSLCFNCAHR-----ILVSHCATNESVESITAFQCPT 58
Query: 184 CRQEC----RQID----------LVDNYFVKDTSEAPSSSDEKSEQ-------------V 216
CR R +D ++D + S S S+ + E+ +
Sbjct: 59 CRHVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVL 118
Query: 217 CTSCEDNAS--AVGFCVECGEWLCKTCIEA-HQRVK-FTKDHLIRKKEDVSESVGASGQR 272
C C+ + + AV CV C C C++A H K FT LI E + S R
Sbjct: 119 CQFCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLI-------EPIPDSHIR 171
Query: 273 PVFCPVHKQEQLKLFCETCDRLTCRDCQLL-EHKEHRYQFLEEAFQNQK----------- 320
+ C H+ E++ ++C T D+L C C+L+ H++H+ L E + K
Sbjct: 172 GLMCLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLI 231
Query: 321 ---GAIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLINEIN-KK 376
+E LLAKL++ +V A++ + ++ E + + Q+ + I T I E +
Sbjct: 232 KRNTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMR 291
Query: 377 GKSLLQQLENVTK--ERQMKLLQQ------QNDITGLSRQVKHVMNFTNWAIAS 422
+ L QQ+ N + ER L+ Q +ND + K++ + A AS
Sbjct: 292 LRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATAS 345
>gi|4557753 midline 1 [Homo sapiens]
Length = 667
Score = 84.0 bits (206), Expect = 8e-16
Identities = 86/354 (24%), Positives = 146/354 (41%), Gaps = 72/354 (20%)
Query: 124 TCAVCQQSLQSRREAEPKLLPCLHSFCLRCLPEPERQLSVPIPGGSNGDIQQVGVIRCPV 183
TC +C + + +P LLPC HS C C + +N ++ + +CP
Sbjct: 9 TCPICLELFE-----DPLLLPCAHSLCFNCAHR-----ILVSHCATNESVESITAFQCPT 58
Query: 184 CRQEC----RQID----------LVDNYFVKDTSEAPSSSDEKSEQ-------------V 216
CR R +D ++D + S S S+ + E+ +
Sbjct: 59 CRHVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVL 118
Query: 217 CTSCEDNAS--AVGFCVECGEWLCKTCIEA-HQRVK-FTKDHLIRKKEDVSESVGASGQR 272
C C+ + + AV CV C C C++A H K FT LI E + S R
Sbjct: 119 CQFCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLI-------EPIPDSHIR 171
Query: 273 PVFCPVHKQEQLKLFCETCDRLTCRDCQLL-EHKEHRYQFLEEAFQNQK----------- 320
+ C H+ E++ ++C T D+L C C+L+ H++H+ L E + K
Sbjct: 172 GLMCLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLI 231
Query: 321 ---GAIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLINEIN-KK 376
+E LLAKL++ +V A++ + ++ E + + Q+ + I T I E +
Sbjct: 232 KRNTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMR 291
Query: 377 GKSLLQQLENVTK--ERQMKLLQQ------QNDITGLSRQVKHVMNFTNWAIAS 422
+ L QQ+ N + ER L+ Q +ND + K++ + A AS
Sbjct: 292 LRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATAS 345
>gi|15451852 midline 1 [Homo sapiens]
Length = 667
Score = 84.0 bits (206), Expect = 8e-16
Identities = 86/354 (24%), Positives = 146/354 (41%), Gaps = 72/354 (20%)
Query: 124 TCAVCQQSLQSRREAEPKLLPCLHSFCLRCLPEPERQLSVPIPGGSNGDIQQVGVIRCPV 183
TC +C + + +P LLPC HS C C + +N ++ + +CP
Sbjct: 9 TCPICLELFE-----DPLLLPCAHSLCFNCAHR-----ILVSHCATNESVESITAFQCPT 58
Query: 184 CRQEC----RQID----------LVDNYFVKDTSEAPSSSDEKSEQ-------------V 216
CR R +D ++D + S S S+ + E+ +
Sbjct: 59 CRHVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVL 118
Query: 217 CTSCEDNAS--AVGFCVECGEWLCKTCIEA-HQRVK-FTKDHLIRKKEDVSESVGASGQR 272
C C+ + + AV CV C C C++A H K FT LI E + S R
Sbjct: 119 CQFCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLI-------EPIPDSHIR 171
Query: 273 PVFCPVHKQEQLKLFCETCDRLTCRDCQLL-EHKEHRYQFLEEAFQNQK----------- 320
+ C H+ E++ ++C T D+L C C+L+ H++H+ L E + K
Sbjct: 172 GLMCLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLI 231
Query: 321 ---GAIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLINEIN-KK 376
+E LLAKL++ +V A++ + ++ E + + Q+ + I T I E +
Sbjct: 232 KRNTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMR 291
Query: 377 GKSLLQQLENVTK--ERQMKLLQQ------QNDITGLSRQVKHVMNFTNWAIAS 422
+ L QQ+ N + ER L+ Q +ND + K++ + A AS
Sbjct: 292 LRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATAS 345
>gi|67089160 promyelocytic leukemia protein isoform 11 [Homo
sapiens]
Length = 781
Score = 82.8 bits (203), Expect = 2e-15
Identities = 73/304 (24%), Positives = 124/304 (40%), Gaps = 41/304 (13%)
Query: 97 PAPAPASAPAPGPSAGPPPGPPASLLDTCAVCQQSLQSRREAEPKLLPCLHSFCLRCLPE 156
P P+ P PS P PAS + + Q Q+ + PKLLPCLH+ C CL
Sbjct: 25 PPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQCQAEAKC-PKLLPCLHTLCSGCL-- 81
Query: 157 PERQLSVPIPGGSNGDIQQVGVIRCPVCRQEC---RQIDLVDNYFVKDTSEAPSSSDE-- 211
+ ++CP+C+ +DN F + S +
Sbjct: 82 ------------------EASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYRQIV 123
Query: 212 KSEQVCTSCEDNASAVGFCVECGEWLCKTCIEAHQRVKFTKDHLIRKKEDVSESV----- 266
++ VCT C+++A +C EC + LC C EAHQ F K E ++SV
Sbjct: 124 DAQAVCTRCKESADF--WCFECEQLLCAKCFEAHQ--WFLKHEARPLAELRNQSVREFLD 179
Query: 267 GASGQRPVFC--PVHKQEQL-KLFCETCDRLTCRDCQLLE--HKEHRYQFLEEAFQNQKG 321
G +FC P H+ L ++C C + C C LL+ H E + E Q Q+
Sbjct: 180 GTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQE- 238
Query: 322 AIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLINEINKKGKSLL 381
++ + L E+ + Q+ + ++ E+ I+ + ++ + + + LL
Sbjct: 239 ELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELL 298
Query: 382 QQLE 385
+ ++
Sbjct: 299 EAVD 302
>gi|67089157 promyelocytic leukemia protein isoform 2 [Homo sapiens]
Length = 611
Score = 82.8 bits (203), Expect = 2e-15
Identities = 73/304 (24%), Positives = 124/304 (40%), Gaps = 41/304 (13%)
Query: 97 PAPAPASAPAPGPSAGPPPGPPASLLDTCAVCQQSLQSRREAEPKLLPCLHSFCLRCLPE 156
P P+ P PS P PAS + + Q Q+ + PKLLPCLH+ C CL
Sbjct: 25 PPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQCQAEAKC-PKLLPCLHTLCSGCL-- 81
Query: 157 PERQLSVPIPGGSNGDIQQVGVIRCPVCRQEC---RQIDLVDNYFVKDTSEAPSSSDE-- 211
+ ++CP+C+ +DN F + S +
Sbjct: 82 ------------------EASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYRQIV 123
Query: 212 KSEQVCTSCEDNASAVGFCVECGEWLCKTCIEAHQRVKFTKDHLIRKKEDVSESV----- 266
++ VCT C+++A +C EC + LC C EAHQ F K E ++SV
Sbjct: 124 DAQAVCTRCKESADF--WCFECEQLLCAKCFEAHQ--WFLKHEARPLAELRNQSVREFLD 179
Query: 267 GASGQRPVFC--PVHKQEQL-KLFCETCDRLTCRDCQLLE--HKEHRYQFLEEAFQNQKG 321
G +FC P H+ L ++C C + C C LL+ H E + E Q Q+
Sbjct: 180 GTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQE- 238
Query: 322 AIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLINEINKKGKSLL 381
++ + L E+ + Q+ + ++ E+ I+ + ++ + + + LL
Sbjct: 239 ELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELL 298
Query: 382 QQLE 385
+ ++
Sbjct: 299 EAVD 302
>gi|15451765 promyelocytic leukemia protein isoform 9 [Homo sapiens]
Length = 829
Score = 82.8 bits (203), Expect = 2e-15
Identities = 73/304 (24%), Positives = 124/304 (40%), Gaps = 41/304 (13%)
Query: 97 PAPAPASAPAPGPSAGPPPGPPASLLDTCAVCQQSLQSRREAEPKLLPCLHSFCLRCLPE 156
P P+ P PS P PAS + + Q Q+ + PKLLPCLH+ C CL
Sbjct: 25 PPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQCQAEAKC-PKLLPCLHTLCSGCL-- 81
Query: 157 PERQLSVPIPGGSNGDIQQVGVIRCPVCRQEC---RQIDLVDNYFVKDTSEAPSSSDE-- 211
+ ++CP+C+ +DN F + S +
Sbjct: 82 ------------------EASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYRQIV 123
Query: 212 KSEQVCTSCEDNASAVGFCVECGEWLCKTCIEAHQRVKFTKDHLIRKKEDVSESV----- 266
++ VCT C+++A +C EC + LC C EAHQ F K E ++SV
Sbjct: 124 DAQAVCTRCKESADF--WCFECEQLLCAKCFEAHQ--WFLKHEARPLAELRNQSVREFLD 179
Query: 267 GASGQRPVFC--PVHKQEQL-KLFCETCDRLTCRDCQLLE--HKEHRYQFLEEAFQNQKG 321
G +FC P H+ L ++C C + C C LL+ H E + E Q Q+
Sbjct: 180 GTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQE- 238
Query: 322 AIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLINEINKKGKSLL 381
++ + L E+ + Q+ + ++ E+ I+ + ++ + + + LL
Sbjct: 239 ELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELL 298
Query: 382 QQLE 385
+ ++
Sbjct: 299 EAVD 302
>gi|67089154 promyelocytic leukemia protein isoform 8 [Homo sapiens]
Length = 435
Score = 82.8 bits (203), Expect = 2e-15
Identities = 73/304 (24%), Positives = 124/304 (40%), Gaps = 41/304 (13%)
Query: 97 PAPAPASAPAPGPSAGPPPGPPASLLDTCAVCQQSLQSRREAEPKLLPCLHSFCLRCLPE 156
P P+ P PS P PAS + + Q Q+ + PKLLPCLH+ C CL
Sbjct: 25 PPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQCQAEAKC-PKLLPCLHTLCSGCL-- 81
Query: 157 PERQLSVPIPGGSNGDIQQVGVIRCPVCRQEC---RQIDLVDNYFVKDTSEAPSSSDE-- 211
+ ++CP+C+ +DN F + S +
Sbjct: 82 ------------------EASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYRQIV 123
Query: 212 KSEQVCTSCEDNASAVGFCVECGEWLCKTCIEAHQRVKFTKDHLIRKKEDVSESV----- 266
++ VCT C+++A +C EC + LC C EAHQ F K E ++SV
Sbjct: 124 DAQAVCTRCKESADF--WCFECEQLLCAKCFEAHQ--WFLKHEARPLAELRNQSVREFLD 179
Query: 267 GASGQRPVFC--PVHKQEQL-KLFCETCDRLTCRDCQLLE--HKEHRYQFLEEAFQNQKG 321
G +FC P H+ L ++C C + C C LL+ H E + E Q Q+
Sbjct: 180 GTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQE- 238
Query: 322 AIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLINEINKKGKSLL 381
++ + L E+ + Q+ + ++ E+ I+ + ++ + + + LL
Sbjct: 239 ELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELL 298
Query: 382 QQLE 385
+ ++
Sbjct: 299 EAVD 302
>gi|4505903 promyelocytic leukemia protein isoform 6 [Homo sapiens]
Length = 633
Score = 82.8 bits (203), Expect = 2e-15
Identities = 73/304 (24%), Positives = 124/304 (40%), Gaps = 41/304 (13%)
Query: 97 PAPAPASAPAPGPSAGPPPGPPASLLDTCAVCQQSLQSRREAEPKLLPCLHSFCLRCLPE 156
P P+ P PS P PAS + + Q Q+ + PKLLPCLH+ C CL
Sbjct: 25 PPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQCQAEAKC-PKLLPCLHTLCSGCL-- 81
Query: 157 PERQLSVPIPGGSNGDIQQVGVIRCPVCRQEC---RQIDLVDNYFVKDTSEAPSSSDE-- 211
+ ++CP+C+ +DN F + S +
Sbjct: 82 ------------------EASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYRQIV 123
Query: 212 KSEQVCTSCEDNASAVGFCVECGEWLCKTCIEAHQRVKFTKDHLIRKKEDVSESV----- 266
++ VCT C+++A +C EC + LC C EAHQ F K E ++SV
Sbjct: 124 DAQAVCTRCKESADF--WCFECEQLLCAKCFEAHQ--WFLKHEARPLAELRNQSVREFLD 179
Query: 267 GASGQRPVFC--PVHKQEQL-KLFCETCDRLTCRDCQLLE--HKEHRYQFLEEAFQNQKG 321
G +FC P H+ L ++C C + C C LL+ H E + E Q Q+
Sbjct: 180 GTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQE- 238
Query: 322 AIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLINEINKKGKSLL 381
++ + L E+ + Q+ + ++ E+ I+ + ++ + + + LL
Sbjct: 239 ELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELL 298
Query: 382 QQLE 385
+ ++
Sbjct: 299 EAVD 302
>gi|15451775 promyelocytic leukemia protein isoform 7 [Homo sapiens]
Length = 423
Score = 82.8 bits (203), Expect = 2e-15
Identities = 73/304 (24%), Positives = 124/304 (40%), Gaps = 41/304 (13%)
Query: 97 PAPAPASAPAPGPSAGPPPGPPASLLDTCAVCQQSLQSRREAEPKLLPCLHSFCLRCLPE 156
P P+ P PS P PAS + + Q Q+ + PKLLPCLH+ C CL
Sbjct: 25 PPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQCQAEAKC-PKLLPCLHTLCSGCL-- 81
Query: 157 PERQLSVPIPGGSNGDIQQVGVIRCPVCRQEC---RQIDLVDNYFVKDTSEAPSSSDE-- 211
+ ++CP+C+ +DN F + S +
Sbjct: 82 ------------------EASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYRQIV 123
Query: 212 KSEQVCTSCEDNASAVGFCVECGEWLCKTCIEAHQRVKFTKDHLIRKKEDVSESV----- 266
++ VCT C+++A +C EC + LC C EAHQ F K E ++SV
Sbjct: 124 DAQAVCTRCKESADF--WCFECEQLLCAKCFEAHQ--WFLKHEARPLAELRNQSVREFLD 179
Query: 267 GASGQRPVFC--PVHKQEQL-KLFCETCDRLTCRDCQLLE--HKEHRYQFLEEAFQNQKG 321
G +FC P H+ L ++C C + C C LL+ H E + E Q Q+
Sbjct: 180 GTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQE- 238
Query: 322 AIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLINEINKKGKSLL 381
++ + L E+ + Q+ + ++ E+ I+ + ++ + + + LL
Sbjct: 239 ELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELL 298
Query: 382 QQLE 385
+ ++
Sbjct: 299 EAVD 302
>gi|15451779 promyelocytic leukemia protein isoform 10 [Homo
sapiens]
Length = 585
Score = 82.8 bits (203), Expect = 2e-15
Identities = 73/304 (24%), Positives = 124/304 (40%), Gaps = 41/304 (13%)
Query: 97 PAPAPASAPAPGPSAGPPPGPPASLLDTCAVCQQSLQSRREAEPKLLPCLHSFCLRCLPE 156
P P+ P PS P PAS + + Q Q+ + PKLLPCLH+ C CL
Sbjct: 25 PPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQCQAEAKC-PKLLPCLHTLCSGCL-- 81
Query: 157 PERQLSVPIPGGSNGDIQQVGVIRCPVCRQEC---RQIDLVDNYFVKDTSEAPSSSDE-- 211
+ ++CP+C+ +DN F + S +
Sbjct: 82 ------------------EASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYRQIV 123
Query: 212 KSEQVCTSCEDNASAVGFCVECGEWLCKTCIEAHQRVKFTKDHLIRKKEDVSESV----- 266
++ VCT C+++A +C EC + LC C EAHQ F K E ++SV
Sbjct: 124 DAQAVCTRCKESADF--WCFECEQLLCAKCFEAHQ--WFLKHEARPLAELRNQSVREFLD 179
Query: 267 GASGQRPVFC--PVHKQEQL-KLFCETCDRLTCRDCQLLE--HKEHRYQFLEEAFQNQKG 321
G +FC P H+ L ++C C + C C LL+ H E + E Q Q+
Sbjct: 180 GTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQE- 238
Query: 322 AIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLINEINKKGKSLL 381
++ + L E+ + Q+ + ++ E+ I+ + ++ + + + LL
Sbjct: 239 ELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELL 298
Query: 382 QQLE 385
+ ++
Sbjct: 299 EAVD 302
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,470,969
Number of Sequences: 37866
Number of extensions: 3033505
Number of successful extensions: 40283
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 561
Number of HSP's successfully gapped in prelim test: 1681
Number of HSP's that attempted gapping in prelim test: 22155
Number of HSP's gapped (non-prelim): 14391
length of query: 1127
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1014
effective length of database: 13,968,660
effective search space: 14164221240
effective search space used: 14164221240
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.