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Search of human proteins with 72534680
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|72534680 sex comb on midleg 1 isoform 1 [Homo sapiens]
(660 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|72534680 sex comb on midleg 1 isoform 1 [Homo sapiens] 1366 0.0
gi|6912642 sex comb on midleg 1 isoform 2 [Homo sapiens] 1201 0.0
gi|5174669 sex comb on midleg-like 2 [Homo sapiens] 601 e-172
gi|158508495 sex comb on midleg-like 4 [Homo sapiens] 337 3e-92
gi|117938328 l(3)mbt-like isoform I [Homo sapiens] 167 3e-41
gi|117938330 l(3)mbt-like isoform II [Homo sapiens] 167 3e-41
gi|55770872 l(3)mbt-like 3 isoform b [Homo sapiens] 163 4e-40
gi|55770870 l(3)mbt-like 3 isoform a [Homo sapiens] 163 4e-40
gi|158138528 l(3)mbt-like 4 [Homo sapiens] 161 2e-39
gi|53692193 Scm-like with four mbt domains 1 [Homo sapiens] 148 2e-35
gi|53692191 Scm-like with four mbt domains 1 [Homo sapiens] 148 2e-35
gi|53692195 Scm-like with four mbt domains 1 [Homo sapiens] 148 2e-35
gi|158508476 mbt domain containing 1 [Homo sapiens] 130 4e-30
gi|20149698 l(3)mbt-like 2 [Homo sapiens] 129 7e-30
gi|71274154 Scm-like with four mbt domains 2 [Homo sapiens] 96 8e-20
gi|82830432 sex comb on midleg-like 1 isoform a [Homo sapiens] 96 1e-19
gi|82830436 sex comb on midleg-like 1 isoform c [Homo sapiens] 96 1e-19
gi|82830430 sex comb on midleg-like 1 isoform c [Homo sapiens] 96 1e-19
gi|82830426 sex comb on midleg-like 1 isoform b [Homo sapiens] 96 1e-19
gi|148612879 polyhomeotic like 3 [Homo sapiens] 69 2e-11
gi|37595530 polyhomeotic-like 2 isoform b [Homo sapiens] 65 2e-10
gi|37595528 polyhomeotic-like 2 isoform a [Homo sapiens] 65 2e-10
gi|62953127 polyhomeotic 1-like [Homo sapiens] 59 1e-08
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 58 3e-08
gi|32699038 sterile alpha motif domain containing 7 [Homo sapiens] 56 9e-08
gi|197927257 sterile alpha motif domain containing 13 isoform 2 ... 52 1e-06
gi|197927255 sterile alpha motif domain containing 13 isoform 2 ... 52 1e-06
gi|58293756 sterile alpha motif domain containing 13 isoform 1 [... 52 1e-06
gi|76881819 sterile alpha motif domain containing 11 [Homo sapiens] 52 2e-06
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 44 5e-04
>gi|72534680 sex comb on midleg 1 isoform 1 [Homo sapiens]
Length = 660
Score = 1366 bits (3536), Expect = 0.0
Identities = 660/660 (100%), Positives = 660/660 (100%)
Query: 1 MLVCYSVLACEILWDLPCSIMGSPLGHFTWDKYLKETCSVPAPVHCFKQSYTPPSNEFKI 60
MLVCYSVLACEILWDLPCSIMGSPLGHFTWDKYLKETCSVPAPVHCFKQSYTPPSNEFKI
Sbjct: 1 MLVCYSVLACEILWDLPCSIMGSPLGHFTWDKYLKETCSVPAPVHCFKQSYTPPSNEFKI 60
Query: 61 SMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNG 120
SMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNG
Sbjct: 61 SMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNG 120
Query: 121 GMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKN 180
GMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKN
Sbjct: 121 GMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKN 180
Query: 181 PHFICPATIGEVRGSEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQPPGTKVV 240
PHFICPATIGEVRGSEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQPPGTKVV
Sbjct: 181 PHFICPATIGEVRGSEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQPPGTKVV 240
Query: 241 IPKNPYPASDVNTEKPSIHSSTKTVLEHQPGQRGRKPGKKRGRTPKTLISHPISAPSKTA 300
IPKNPYPASDVNTEKPSIHSSTKTVLEHQPGQRGRKPGKKRGRTPKTLISHPISAPSKTA
Sbjct: 241 IPKNPYPASDVNTEKPSIHSSTKTVLEHQPGQRGRKPGKKRGRTPKTLISHPISAPSKTA 300
Query: 301 EPLKFPKKRGPKPGSKRKPRTLLNPPPASPTTSTPEPDTSTVPQDAATIPSSAMQAPTVC 360
EPLKFPKKRGPKPGSKRKPRTLLNPPPASPTTSTPEPDTSTVPQDAATIPSSAMQAPTVC
Sbjct: 301 EPLKFPKKRGPKPGSKRKPRTLLNPPPASPTTSTPEPDTSTVPQDAATIPSSAMQAPTVC 360
Query: 361 IYLNKNGSTGPHLDKKKVQQLPDHFGPARASVVLQQAVQACIDCAYHQKTVFSFLKQGHG 420
IYLNKNGSTGPHLDKKKVQQLPDHFGPARASVVLQQAVQACIDCAYHQKTVFSFLKQGHG
Sbjct: 361 IYLNKNGSTGPHLDKKKVQQLPDHFGPARASVVLQQAVQACIDCAYHQKTVFSFLKQGHG 420
Query: 421 GEVISAVFDREQHTLNLPAVNSITYVLRFLEKLCHNLRSDNLFGNQPFTQTHLSLTAIEY 480
GEVISAVFDREQHTLNLPAVNSITYVLRFLEKLCHNLRSDNLFGNQPFTQTHLSLTAIEY
Sbjct: 421 GEVISAVFDREQHTLNLPAVNSITYVLRFLEKLCHNLRSDNLFGNQPFTQTHLSLTAIEY 480
Query: 481 SHSHDRYLPGETFVLGNSLARSLEPHSDSMDSASNPTNLVSTSQRHRPLLSSCGLPPSTA 540
SHSHDRYLPGETFVLGNSLARSLEPHSDSMDSASNPTNLVSTSQRHRPLLSSCGLPPSTA
Sbjct: 481 SHSHDRYLPGETFVLGNSLARSLEPHSDSMDSASNPTNLVSTSQRHRPLLSSCGLPPSTA 540
Query: 541 SAVRRLCSRGVLKGSNERRDMESFWKLNRSPGSDRYLESRDASRLSGRDPSSWTVEDVMQ 600
SAVRRLCSRGVLKGSNERRDMESFWKLNRSPGSDRYLESRDASRLSGRDPSSWTVEDVMQ
Sbjct: 541 SAVRRLCSRGVLKGSNERRDMESFWKLNRSPGSDRYLESRDASRLSGRDPSSWTVEDVMQ 600
Query: 601 FVREADPQLGPHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKLSYHIDRLKQGKF 660
FVREADPQLGPHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKLSYHIDRLKQGKF
Sbjct: 601 FVREADPQLGPHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKLSYHIDRLKQGKF 660
>gi|6912642 sex comb on midleg 1 isoform 2 [Homo sapiens]
Length = 591
Score = 1201 bits (3107), Expect = 0.0
Identities = 590/612 (96%), Positives = 590/612 (96%), Gaps = 22/612 (3%)
Query: 49 QSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSA 108
QSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSA
Sbjct: 2 QSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSA 61
Query: 109 EIQPIGNCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFFK 168
EIQPIGNCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFFK
Sbjct: 62 EIQPIGNCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFFK 121
Query: 169 MGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLT 228
MGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLT
Sbjct: 122 MGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLT 181
Query: 229 GDNLQPPGTKVVIPKNPYPASDVNTEKPSIHSSTKTVLEHQPGQRGRKPGKKRGRTPKTL 288
GDNLQPPGTKVVIPKNPYPASDVNTEKPSIHSSTKTVLEHQPGQRGRKPGKKRGRTPKTL
Sbjct: 182 GDNLQPPGTKVVIPKNPYPASDVNTEKPSIHSSTKTVLEHQPGQRGRKPGKKRGRTPKTL 241
Query: 289 ISHPISAPSKTAEPLKFPKKRGPKPGSKRKPRTLLNPPPASPTTSTPEPDTSTVPQDAAT 348
ISHPISAPSKTAEPLKFPKKRGPKPGSKRKPRTLLNPPPASPTTSTPEPDTSTVPQDAAT
Sbjct: 242 ISHPISAPSKTAEPLKFPKKRGPKPGSKRKPRTLLNPPPASPTTSTPEPDTSTVPQDAAT 301
Query: 349 IPSSAMQAPTVCIYLNKNGSTGPHLDKKKVQQLPDHFGPARASVVLQQAVQACIDCAYHQ 408
IPSSAMQAPTVCIYLNKNGSTGPHLDKKKVQQLPDHFGPARASVVLQQAVQACIDCAYHQ
Sbjct: 302 IPSSAMQAPTVCIYLNKNGSTGPHLDKKKVQQLPDHFGPARASVVLQQAVQACIDCAYHQ 361
Query: 409 KTVFSFLKQGHGGEVISAVFDREQHTLNLPAVNSITYVLRFLEKLCHNLRSDNLFGNQPF 468
KTVFSFLKQGHGGEVISAVFDREQHTLNLPAVNSITYVLRFLEKLCHNLRSDNLFGNQPF
Sbjct: 362 KTVFSFLKQGHGGEVISAVFDREQHTLNLPAVNSITYVLRFLEKLCHNLRSDNLFGNQPF 421
Query: 469 TQTHLSLTAIEYSHSHDRYLPGETFVLGNSLARSLEPHSDSMDSASNPTNLVSTSQRHRP 528
TQTHLSLTAIEYSHSHDRYLPGETFVLGNSLARSLEPHSDSMDSASNPTNLVSTSQRHRP
Sbjct: 422 TQTHLSLTAIEYSHSHDRYLPGETFVLGNSLARSLEPHSDSMDSASNPTNLVSTSQRHRP 481
Query: 529 LLSSCGLPPSTASAVRRLCSRGVLKGSNERRDMESFWKLNRSPGSDRYLESRDASRLSGR 588
LLSSCGLPPSTASAVRRLCSR GSDRYLESRDASRLSGR
Sbjct: 482 LLSSCGLPPSTASAVRRLCSR----------------------GSDRYLESRDASRLSGR 519
Query: 589 DPSSWTVEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKL 648
DPSSWTVEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKL
Sbjct: 520 DPSSWTVEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKL 579
Query: 649 SYHIDRLKQGKF 660
SYHIDRLKQGKF
Sbjct: 580 SYHIDRLKQGKF 591
Score = 65.9 bits (159), Expect = 1e-10
Identities = 39/109 (35%), Positives = 57/109 (52%), Gaps = 3/109 (2%)
Query: 21 MGSPLGHFTWDKYLKETCSVP--APVHCF-KQSYTPPSNEFKISMKLEAQDPRNTTSTCI 77
+G L +W +L +T + AP+ F K+ +P N FK+ MKLEA D +N C
Sbjct: 80 LGFRLNASSWPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICP 139
Query: 78 ATVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPP 126
AT+ + G+ + + DG D+W DS +I P+G C G LQPP
Sbjct: 140 ATIGEVRGSEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQPP 188
>gi|5174669 sex comb on midleg-like 2 [Homo sapiens]
Length = 700
Score = 601 bits (1549), Expect = e-172
Identities = 326/676 (48%), Positives = 428/676 (63%), Gaps = 52/676 (7%)
Query: 28 FTWDKYLKETCSVPAPVHCFKQSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGAR 87
F W++YLKET S+ AP CF+QS PP N+FK+ MKLEA+DPRN TS CIATV+G+TGAR
Sbjct: 33 FHWEEYLKETGSISAPSECFRQSQIPPVNDFKVGMKLEARDPRNATSVCIATVIGITGAR 92
Query: 88 LRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGA 147
LRLRLDGSDN+NDFWRLVDS +IQP+G CEK G +LQPPLG+++N SSWPMFLLKTLNG+
Sbjct: 93 LRLRLDGSDNRNDFWRLVDSPDIQPVGTCEKEGDLLQPPLGYQMNTSSWPMFLLKTLNGS 152
Query: 148 EMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFDGWRGA 207
EMA +F KEPP P N FK+GMKLEA+D+KNP+ ICPATIG+V+G EV +TFDGW GA
Sbjct: 153 EMASATLFKKEPPKPPLNNFKVGMKLEAIDKKNPYLICPATIGDVKGDEVHITFDGWSGA 212
Query: 208 FDYWCRFDSRDIFPVGWCSLTGDNLQPPGTKVVIPKN--PYPASDVNTEKPSIHSSTKTV 265
FDYWC++DSRDIFP GWC LTGD LQPPGT V I KN +S + S+ S KT
Sbjct: 213 FDYWCKYDSRDIFPAGWCRLTGDVLQPPGTSVPIVKNIAKTESSPSEASQHSMQSPQKTT 272
Query: 266 LEHQPGQRGRKPGKKRGRTPKTLISHPISAPSKTAEPLKFPKKRGPKPGSKRKPRTLLNP 325
L P Q+ R+ + + P + S + T P+K+GP G K KP ++
Sbjct: 273 L-ILPTQQVRRSSRIKPPGPTAVPKRSSSVKNIT------PRKKGPNSGKKEKPLPVICS 325
Query: 326 PPASPTTSTPEPDTSTVPQDAATIPSSAMQAPTVCIYLNKNGSTGPHLDKKKVQQLPDHF 385
A+ S D + +D A+ P + + TVC+Y+NK+G+ GPHLD K++QQLPDHF
Sbjct: 326 TSAASLKSLTR-DRGMLYKDVASGPCKIVMS-TVCVYVNKHGNFGPHLDPKRIQQLPDHF 383
Query: 386 GPARASVVLQQAVQACIDCAYHQKTVFSFLK-QGHGGEVISAVFDREQHTLNLPAVNSIT 444
GP +VVL++ VQAC+DCA KTVF +LK GGEVI+A FD E H++ LP VNS +
Sbjct: 384 GPGPVNVVLRRIVQACVDCALETKTVFGYLKPDNRGGEVITASFDGETHSIQLPPVNSAS 443
Query: 445 YVLRFLEKLCHNLRSDNLFGNQPFT----QTHLSL-----------------------TA 477
+ LRFLE CH+L+ DNL +QPF+ TH S
Sbjct: 444 FALRFLENFCHSLQCDNLLSSQPFSSSRGHTHSSAEHDKNQSAKEDVTERQSTKRSPQQT 503
Query: 478 IEYSHSHDRYLP--------GE-TFVLGNSLARSLEPHSDSMDSASNPTNLVSTSQRHRP 528
+ Y LP GE F G+++ + DS S+ N N ++ + R+
Sbjct: 504 VPYVVPLSPKLPKTKEYASEGEPLFAGGSAIPKEENLSEDSKSSSLNSGNYLNPACRNPM 563
Query: 529 LLSSCGLPPSTASAVRRLCSRGVLKGSNERRDMESFWKLNRSPGSDRYLESRDASRLS-- 586
+ + + S S V S + E +++ R + Y+ D S L
Sbjct: 564 YIHTSVSQDFSRSVPGTTSSPLVGDISPKSSPHEVKFQMQRKSEAPSYIAVPDPSVLKQG 623
Query: 587 -GRDPSSWTVEDVMQFVREADPQL-GPHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGP 644
+DPS+W+V++V+QF++ DPQ+ GP ADLFR+HEIDGKAL LL+SD+MMKYMGLKLGP
Sbjct: 624 FSKDPSTWSVDEVIQFMKHTDPQISGPLADLFRQHEIDGKALFLLKSDVMMKYMGLKLGP 683
Query: 645 ALKLSYHIDRLKQGKF 660
ALKL Y+I++LK+GK+
Sbjct: 684 ALKLCYYIEKLKEGKY 699
>gi|158508495 sex comb on midleg-like 4 [Homo sapiens]
Length = 414
Score = 337 bits (863), Expect = 3e-92
Identities = 201/416 (48%), Positives = 266/416 (63%), Gaps = 30/416 (7%)
Query: 272 QRGRKPGKKRGR-----TPKTLISHPISAPSKTAEP-LKFPKKRGPKPGSKRKPRTLLNP 325
Q R PG+KRGR TP + H + + S + P +K PKKRG KPG K K R L+ P
Sbjct: 2 QSQRIPGRKRGRPSLHSTPMKMAVHNLYSASAGSLPAVKIPKKRGRKPGYKIKSRVLMTP 61
Query: 326 PPASPTTSTPEPDTSTVPQDAATIPS-SAMQAPTVCIYLNKNGSTGPHLDKKKVQQLPDH 384
SP STPEPD S++PQDAAT+PS +A QA TVC+Y+NK + GP+L++KKVQQLP+H
Sbjct: 62 LALSPPRSTPEPDLSSIPQDAATVPSLAAPQALTVCLYINKQANAGPYLERKKVQQLPEH 121
Query: 385 FGPARASVVLQQAVQACIDCAYHQKTVFSFLKQGHGGEV--ISAVFDREQHTLNLPAVNS 442
FGP R S VLQQAVQACIDCA+ QK VFS +KQG+GGE+ +SA FD +QH +LP VNS
Sbjct: 122 FGPERPSAVLQQAVQACIDCAHQQKLVFSLVKQGYGGEMVSVSASFDGKQHLRSLPVVNS 181
Query: 443 ITYVLRFLEKLCHNLRSDNLFGNQPFTQTHLSLTAIEYSHSHDRYLPGETFVLGNSLARS 502
I YVLRFL KLC +L D+LF +QPF + + ++ R +T L
Sbjct: 182 IGYVLRFLAKLCRSLLCDDLFSHQPFPRGCSASEKVQ-EKEEGRMESVKTVTTEEYLVNP 240
Query: 503 LEPHSDSMDSAS---------NPTNLVSTSQRHRPLLSSCGLPPSTASAVRR--LCSRGV 551
+ + S+D+++ +P++ + +++ G P +TA R + S G
Sbjct: 241 VGMNRYSVDTSASTFNHRGSLHPSSSLYCKRQNSGDSHLGGGPAATAGGPRTSPMSSGGP 300
Query: 552 L------KGSNERRDMESFWKLNRSPGSDRYLESRDASRLSGRDPSSWTVEDVMQFVREA 605
S+ +R+ S + NR S +++DA R R+PS+WTVEDV+ FV++A
Sbjct: 301 SAPGLRPPASSPKRNTTSL-EGNRCASSPSQ-DAQDARRPRSRNPSAWTVEDVVWFVKDA 358
Query: 606 DPQ-LGPHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKLSYHIDRLKQGKF 660
DPQ LGPH +LFRKHEIDG ALLLL+SDM+MKY+GLKLGPALKL YHID+LKQ KF
Sbjct: 359 DPQALGPHVELFRKHEIDGNALLLLKSDMVMKYLGLKLGPALKLCYHIDKLKQAKF 414
>gi|117938328 l(3)mbt-like isoform I [Homo sapiens]
Length = 772
Score = 167 bits (423), Expect = 3e-41
Identities = 90/210 (42%), Positives = 119/210 (56%), Gaps = 4/210 (1%)
Query: 28 FTWDKYLKETCSVPAPVHCFK--QSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTG 85
++W+ YL+E ++ APV F+ Q+ T N FK+ MKLE DP++ + I TV + G
Sbjct: 206 WSWESYLEEQKAITAPVSLFQDSQAVTHNKNGFKLGMKLEGIDPQHPSMYFILTVAEVCG 265
Query: 86 ARLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLGFRLNASSWPMFLLKTLN 145
RLRL DG +DFW +S +I P G EK G LQPP G++ SW +L T
Sbjct: 266 YRLRLHFDGYSECHDFWVNANSPDIHPAGWFEKTGHKLQPPKGYKEEEFSWSQYLRSTR- 324
Query: 146 GAEMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFDGWR 205
A+ AP +F + SP F++GMKLEAVDR NP +C A++ +V S LV FD W
Sbjct: 325 -AQAAPKHLFVSQSHSPPPLGFQVGMKLEAVDRMNPSLVCVASVTDVVDSRFLVHFDNWD 383
Query: 206 GAFDYWCRFDSRDIFPVGWCSLTGDNLQPP 235
+DYWC S I PVGWC G L PP
Sbjct: 384 DTYDYWCDPSSPYIHPVGWCQKQGKPLTPP 413
Score = 152 bits (385), Expect = 7e-37
Identities = 87/224 (38%), Positives = 121/224 (54%), Gaps = 12/224 (5%)
Query: 28 FTWDKYLKETCSVPAPVHCF-KQSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGA 86
F+W +YL+ T + AP H F QS++PP F++ MKLEA D N + C+A+V + +
Sbjct: 314 FSWSQYLRSTRAQAAPKHLFVSQSHSPPPLGFQVGMKLEAVDRMNPSLVCVASVTDVVDS 373
Query: 87 RLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLGFR-LNASSWPMFLLKTLN 145
R + D D+ D+W S I P+G C+K G L PP + + W +L +T
Sbjct: 374 RFLVHFDNWDDTYDYWCDPSSPYIHPVGWCQKQGKPLTPPQDYPDPDNFCWEKYLEET-- 431
Query: 146 GAEMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFDGWR 205
GA P F PP H+F + MKLEAVDR+NP I A++ +V + + FDGW
Sbjct: 432 GASAVPTWAFKVRPP---HSFL-VNMKLEAVDRRNPALIRVASVEDVEDHRIKIHFDGWS 487
Query: 206 GAFDYWCRFDSRDIFPVGWCSLTGDNLQPPGTKVVIPKNPYPAS 249
+D+W D DI P GWCS TG LQPP + P+ P AS
Sbjct: 488 HGYDFWIDADHPDIHPAGWCSKTGHPLQPP----LGPREPSSAS 527
Score = 82.4 bits (202), Expect = 1e-15
Identities = 52/158 (32%), Positives = 75/158 (47%), Gaps = 16/158 (10%)
Query: 18 CSIMGSPL---------GHFTWDKYLKETCSVPAPVHCFKQSYTPPSNEFKISMKLEAQD 68
C G PL +F W+KYL+ET + P FK P + F ++MKLEA D
Sbjct: 403 CQKQGKPLTPPQDYPDPDNFCWEKYLEETGASAVPTWAFK---VRPPHSFLVNMKLEAVD 459
Query: 69 PRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLG 128
RN +A+V + R+++ DG + DFW D +I P G C K G LQPPLG
Sbjct: 460 RRNPALIRVASVEDVEDHRIKIHFDGWSHGYDFWIDADHPDIHPAGWCSKTGHPLQPPLG 519
Query: 129 FRLNASS----WPMFLLKTLNGAEMAPIRIFHKEPPSP 162
R +S+ P ++L + H++ P+P
Sbjct: 520 PREPSSASPGGCPPLSYRSLPHTRTSKYSFHHRKCPTP 557
>gi|117938330 l(3)mbt-like isoform II [Homo sapiens]
Length = 738
Score = 167 bits (423), Expect = 3e-41
Identities = 90/210 (42%), Positives = 119/210 (56%), Gaps = 4/210 (1%)
Query: 28 FTWDKYLKETCSVPAPVHCFK--QSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTG 85
++W+ YL+E ++ APV F+ Q+ T N FK+ MKLE DP++ + I TV + G
Sbjct: 206 WSWESYLEEQKAITAPVSLFQDSQAVTHNKNGFKLGMKLEGIDPQHPSMYFILTVAEVCG 265
Query: 86 ARLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLGFRLNASSWPMFLLKTLN 145
RLRL DG +DFW +S +I P G EK G LQPP G++ SW +L T
Sbjct: 266 YRLRLHFDGYSECHDFWVNANSPDIHPAGWFEKTGHKLQPPKGYKEEEFSWSQYLRSTR- 324
Query: 146 GAEMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFDGWR 205
A+ AP +F + SP F++GMKLEAVDR NP +C A++ +V S LV FD W
Sbjct: 325 -AQAAPKHLFVSQSHSPPPLGFQVGMKLEAVDRMNPSLVCVASVTDVVDSRFLVHFDNWD 383
Query: 206 GAFDYWCRFDSRDIFPVGWCSLTGDNLQPP 235
+DYWC S I PVGWC G L PP
Sbjct: 384 DTYDYWCDPSSPYIHPVGWCQKQGKPLTPP 413
Score = 152 bits (385), Expect = 7e-37
Identities = 87/224 (38%), Positives = 121/224 (54%), Gaps = 12/224 (5%)
Query: 28 FTWDKYLKETCSVPAPVHCF-KQSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGA 86
F+W +YL+ T + AP H F QS++PP F++ MKLEA D N + C+A+V + +
Sbjct: 314 FSWSQYLRSTRAQAAPKHLFVSQSHSPPPLGFQVGMKLEAVDRMNPSLVCVASVTDVVDS 373
Query: 87 RLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLGFR-LNASSWPMFLLKTLN 145
R + D D+ D+W S I P+G C+K G L PP + + W +L +T
Sbjct: 374 RFLVHFDNWDDTYDYWCDPSSPYIHPVGWCQKQGKPLTPPQDYPDPDNFCWEKYLEET-- 431
Query: 146 GAEMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFDGWR 205
GA P F PP H+F + MKLEAVDR+NP I A++ +V + + FDGW
Sbjct: 432 GASAVPTWAFKVRPP---HSFL-VNMKLEAVDRRNPALIRVASVEDVEDHRIKIHFDGWS 487
Query: 206 GAFDYWCRFDSRDIFPVGWCSLTGDNLQPPGTKVVIPKNPYPAS 249
+D+W D DI P GWCS TG LQPP + P+ P AS
Sbjct: 488 HGYDFWIDADHPDIHPAGWCSKTGHPLQPP----LGPREPSSAS 527
Score = 82.4 bits (202), Expect = 1e-15
Identities = 52/158 (32%), Positives = 75/158 (47%), Gaps = 16/158 (10%)
Query: 18 CSIMGSPL---------GHFTWDKYLKETCSVPAPVHCFKQSYTPPSNEFKISMKLEAQD 68
C G PL +F W+KYL+ET + P FK P + F ++MKLEA D
Sbjct: 403 CQKQGKPLTPPQDYPDPDNFCWEKYLEETGASAVPTWAFK---VRPPHSFLVNMKLEAVD 459
Query: 69 PRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLG 128
RN +A+V + R+++ DG + DFW D +I P G C K G LQPPLG
Sbjct: 460 RRNPALIRVASVEDVEDHRIKIHFDGWSHGYDFWIDADHPDIHPAGWCSKTGHPLQPPLG 519
Query: 129 FRLNASS----WPMFLLKTLNGAEMAPIRIFHKEPPSP 162
R +S+ P ++L + H++ P+P
Sbjct: 520 PREPSSASPGGCPPLSYRSLPHTRTSKYSFHHRKCPTP 557
>gi|55770872 l(3)mbt-like 3 isoform b [Homo sapiens]
Length = 755
Score = 163 bits (413), Expect = 4e-40
Identities = 87/210 (41%), Positives = 119/210 (56%), Gaps = 5/210 (2%)
Query: 30 WDKYLKETCSVPAPVHCFK--QSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGAR 87
W YL+E +V P FK QS+ N FK+ MKLE DP + + C+ TV + G R
Sbjct: 209 WASYLEEEKAVAVPAKLFKEHQSFPYNKNGFKVGMKLEGVDPEHQSVYCVLTVAEVCGYR 268
Query: 88 LRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGA 147
++L DG + DFW D+ +I P+G CEK G L PP G++ +W + LKT A
Sbjct: 269 IKLHFDGYSDCYDFWVNADALDIHPVGWCEKTGHKLHPPKGYKEEEFNWQTY-LKTCK-A 326
Query: 148 EMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFDGWRGA 207
+ AP +F + + + F++GMKLEAVD+KNP FIC AT+ ++ + LV FD W +
Sbjct: 327 QAAPKSLFENQNITVIPSGFRVGMKLEAVDKKNPSFICVATVTDMVDNRFLVHFDNWDES 386
Query: 208 FDYWCRFDSRDIFPVGWCSLTGDNL-QPPG 236
+DYWC S I PVGWC L PPG
Sbjct: 387 YDYWCEASSPHIHPVGWCKEHRRTLITPPG 416
Score = 147 bits (372), Expect = 2e-35
Identities = 85/210 (40%), Positives = 112/210 (53%), Gaps = 8/210 (3%)
Query: 28 FTWDKYLKETCSVPAPVHCFK-QSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGA 86
F W YLK + AP F+ Q+ T + F++ MKLEA D +N + C+ATV +
Sbjct: 315 FNWQTYLKTCKAQAAPKSLFENQNITVIPSGFRVGMKLEAVDKKNPSFICVATVTDMVDN 374
Query: 87 RLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLGF-RLNASSWPMFLLKTLN 145
R + D D D+W S I P+G C+++ L P G+ + SW +L +T
Sbjct: 375 RFLVHFDNWDESYDYWCEASSPHIHPVGWCKEHRRTLITPPGYPNVKHFSWDKYLEET-- 432
Query: 146 GAEMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFDGWR 205
+ AP R F +PP H F K MKLE VD++NP FI AT+ + V V FDGW
Sbjct: 433 NSLPAPARAFKVKPP---HGFQKK-MKLEVVDKRNPMFIRVATVADTDDHRVKVHFDGWN 488
Query: 206 GAFDYWCRFDSRDIFPVGWCSLTGDNLQPP 235
+DYW DS DI PVGWCS TG LQPP
Sbjct: 489 NCYDYWIDADSPDIHPVGWCSKTGHPLQPP 518
Score = 90.1 bits (222), Expect = 6e-18
Identities = 46/101 (45%), Positives = 59/101 (58%), Gaps = 3/101 (2%)
Query: 27 HFTWDKYLKETCSVPAPVHCFKQSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGA 86
HF+WDKYL+ET S+PAP FK P + F+ MKLE D RN +ATV
Sbjct: 422 HFSWDKYLEETNSLPAPARAFK---VKPPHGFQKKMKLEVVDKRNPMFIRVATVADTDDH 478
Query: 87 RLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPL 127
R+++ DG +N D+W DS +I P+G C K G LQPPL
Sbjct: 479 RVKVHFDGWNNCYDYWIDADSPDIHPVGWCSKTGHPLQPPL 519
Score = 49.3 bits (116), Expect = 1e-05
Identities = 22/58 (37%), Positives = 37/58 (63%), Gaps = 1/58 (1%)
Query: 591 SSWTVEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKL 648
S W+ ++V +F++ P H +F+ +IDG+A LL+ ++K M +KLGPALK+
Sbjct: 681 SKWSTDEVSEFIQSL-PGCEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALKI 737
>gi|55770870 l(3)mbt-like 3 isoform a [Homo sapiens]
Length = 780
Score = 163 bits (413), Expect = 4e-40
Identities = 87/210 (41%), Positives = 119/210 (56%), Gaps = 5/210 (2%)
Query: 30 WDKYLKETCSVPAPVHCFK--QSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGAR 87
W YL+E +V P FK QS+ N FK+ MKLE DP + + C+ TV + G R
Sbjct: 234 WASYLEEEKAVAVPAKLFKEHQSFPYNKNGFKVGMKLEGVDPEHQSVYCVLTVAEVCGYR 293
Query: 88 LRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGA 147
++L DG + DFW D+ +I P+G CEK G L PP G++ +W + LKT A
Sbjct: 294 IKLHFDGYSDCYDFWVNADALDIHPVGWCEKTGHKLHPPKGYKEEEFNWQTY-LKTCK-A 351
Query: 148 EMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFDGWRGA 207
+ AP +F + + + F++GMKLEAVD+KNP FIC AT+ ++ + LV FD W +
Sbjct: 352 QAAPKSLFENQNITVIPSGFRVGMKLEAVDKKNPSFICVATVTDMVDNRFLVHFDNWDES 411
Query: 208 FDYWCRFDSRDIFPVGWCSLTGDNL-QPPG 236
+DYWC S I PVGWC L PPG
Sbjct: 412 YDYWCEASSPHIHPVGWCKEHRRTLITPPG 441
Score = 147 bits (372), Expect = 2e-35
Identities = 85/210 (40%), Positives = 112/210 (53%), Gaps = 8/210 (3%)
Query: 28 FTWDKYLKETCSVPAPVHCFK-QSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGA 86
F W YLK + AP F+ Q+ T + F++ MKLEA D +N + C+ATV +
Sbjct: 340 FNWQTYLKTCKAQAAPKSLFENQNITVIPSGFRVGMKLEAVDKKNPSFICVATVTDMVDN 399
Query: 87 RLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLGF-RLNASSWPMFLLKTLN 145
R + D D D+W S I P+G C+++ L P G+ + SW +L +T
Sbjct: 400 RFLVHFDNWDESYDYWCEASSPHIHPVGWCKEHRRTLITPPGYPNVKHFSWDKYLEET-- 457
Query: 146 GAEMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFDGWR 205
+ AP R F +PP H F K MKLE VD++NP FI AT+ + V V FDGW
Sbjct: 458 NSLPAPARAFKVKPP---HGFQKK-MKLEVVDKRNPMFIRVATVADTDDHRVKVHFDGWN 513
Query: 206 GAFDYWCRFDSRDIFPVGWCSLTGDNLQPP 235
+DYW DS DI PVGWCS TG LQPP
Sbjct: 514 NCYDYWIDADSPDIHPVGWCSKTGHPLQPP 543
Score = 90.1 bits (222), Expect = 6e-18
Identities = 46/101 (45%), Positives = 59/101 (58%), Gaps = 3/101 (2%)
Query: 27 HFTWDKYLKETCSVPAPVHCFKQSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGA 86
HF+WDKYL+ET S+PAP FK P + F+ MKLE D RN +ATV
Sbjct: 447 HFSWDKYLEETNSLPAPARAFK---VKPPHGFQKKMKLEVVDKRNPMFIRVATVADTDDH 503
Query: 87 RLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPL 127
R+++ DG +N D+W DS +I P+G C K G LQPPL
Sbjct: 504 RVKVHFDGWNNCYDYWIDADSPDIHPVGWCSKTGHPLQPPL 544
Score = 49.3 bits (116), Expect = 1e-05
Identities = 22/58 (37%), Positives = 37/58 (63%), Gaps = 1/58 (1%)
Query: 591 SSWTVEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKL 648
S W+ ++V +F++ P H +F+ +IDG+A LL+ ++K M +KLGPALK+
Sbjct: 706 SKWSTDEVSEFIQSL-PGCEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALKI 762
>gi|158138528 l(3)mbt-like 4 [Homo sapiens]
Length = 623
Score = 161 bits (408), Expect = 2e-39
Identities = 89/213 (41%), Positives = 121/213 (56%), Gaps = 5/213 (2%)
Query: 26 GHFTWDKYLKETCSVPAPVHCFK--QSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGL 83
G ++W+ YLKE +V APV F QS+ N F+I M+LE DPR+ + C+ +V +
Sbjct: 50 GAWSWEWYLKEQKAVAAPVELFSKDQSFPEHENGFQIGMRLEGIDPRHPSVFCVLSVAEV 109
Query: 84 TGARLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLGFRLNASSWPMFLLKT 143
G RLRL DG + DFW S +I P+G CEK L P G+R + W M LK
Sbjct: 110 CGYRLRLHFDGYLSCYDFWTNAGSPDIHPVGWCEKTKHELHIPKGYRKDKFVW-MDYLKA 168
Query: 144 LNGAEMAPIRIF-HKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFD 202
+ AP ++F ++ P P F++GMKLEAVDRKNP +C ATI ++ +LV FD
Sbjct: 169 CK-LQNAPKKLFRNRSPNGPMSKEFQVGMKLEAVDRKNPSLVCVATIADIVEDRLLVHFD 227
Query: 203 GWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQPP 235
W ++DYWC +S + PVGWC G L P
Sbjct: 228 NWDDSYDYWCDVNSPYVQPVGWCQENGRTLIAP 260
Score = 143 bits (361), Expect = 4e-34
Identities = 83/211 (39%), Positives = 111/211 (52%), Gaps = 9/211 (4%)
Query: 28 FTWDKYLKETCSVPAPVHCFKQSYT--PPSNEFKISMKLEAQDPRNTTSTCIATVVGLTG 85
F W YLK AP F+ P S EF++ MKLEA D +N + C+AT+ +
Sbjct: 160 FVWMDYLKACKLQNAPKKLFRNRSPNGPMSKEFQVGMKLEAVDRKNPSLVCVATIADIVE 219
Query: 86 ARLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLGFRLNAS-SWPMFLLKTL 144
RL + D D+ D+W V+S +QP+G C++NG L P G+ + SW +L T
Sbjct: 220 DRLLVHFDNWDDSYDYWCDVNSPYVQPVGWCQENGRTLIAPQGYPNPENFSWTEYLEATQ 279
Query: 145 NGAEMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFDGW 204
A P ++F P H F MKLE VD++NP I ATI +V V V FDGW
Sbjct: 280 TNA--VPAKVFKMRLP---HGFLP-NMKLEVVDKRNPRLIRVATIVDVDDQRVKVHFDGW 333
Query: 205 RGAFDYWCRFDSRDIFPVGWCSLTGDNLQPP 235
+DYW DS DI P+GWC +TG L+ P
Sbjct: 334 DHKYDYWVEADSPDIHPIGWCDVTGHPLEVP 364
Score = 67.0 bits (162), Expect = 5e-11
Identities = 36/100 (36%), Positives = 54/100 (54%), Gaps = 3/100 (3%)
Query: 27 HFTWDKYLKETCSVPAPVHCFKQSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGA 86
+F+W +YL+ T + P FK + F +MKLE D RN +AT+V +
Sbjct: 268 NFSWTEYLEATQTNAVPAKVFKMRL---PHGFLPNMKLEVVDKRNPRLIRVATIVDVDDQ 324
Query: 87 RLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPP 126
R+++ DG D+K D+W DS +I PIG C+ G L+ P
Sbjct: 325 RVKVHFDGWDHKYDYWVEADSPDIHPIGWCDVTGHPLEVP 364
Score = 53.1 bits (126), Expect = 8e-07
Identities = 29/58 (50%), Positives = 39/58 (67%), Gaps = 5/58 (8%)
Query: 593 WTVEDVMQFVREADPQLG--PHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKL 648
WTV++V +FV+ LG HA F+K +IDGKA LLL ++K M +KLGPALK+
Sbjct: 543 WTVDEVAEFVQSL---LGCEEHAKCFKKEQIDGKAFLLLTQTDIVKVMKIKLGPALKI 597
>gi|53692193 Scm-like with four mbt domains 1 [Homo sapiens]
Length = 866
Score = 148 bits (373), Expect = 2e-35
Identities = 183/738 (24%), Positives = 285/738 (38%), Gaps = 121/738 (16%)
Query: 30 WDKYLKET----CSVPAPVHCFKQSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTG 85
WD++L++T CS P P+ ++ P + +LE Q +++ ST I TVV G
Sbjct: 130 WDEFLRQTLIGACSPPVPLLEGLRNGRNPLDLIAPGSRLECQAFQDSLSTWIVTVVENIG 189
Query: 86 ARLRLRLDGSDNKNDF--WRLVDSAEIQPIGNCEKNGGMLQPPLGFR--LNASSWPMFLL 141
RL+LR +G ++ +++ W + +G + G LQPP R N + W L
Sbjct: 190 GRLKLRYEGLESSDNYEHWLYYLDPFLHHVGWAAQQGYELQPPSAIRHLKNEAEWQEILA 249
Query: 142 KTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEV-LVT 200
K E K+ + F + MKLEAVD +P I PAT+ +V + LV
Sbjct: 250 KVKEEEEEPLPSYLFKDKQVIGIHTFSVNMKLEAVDPWSPFGISPATVVKVFDEKYFLVE 309
Query: 201 FDGWR----GAFDYWCRFDSRDIFPVGWCSLTGDNLQPPGTKVVIPKNPYPASDVN---- 252
D R + C DS IFPV W G ++ PP YP+ D +
Sbjct: 310 MDDLRPENHARRSFVCHADSPGIFPVQWSLKNGLHISPPPG--------YPSQDFDWADY 361
Query: 253 -----TEKPSIHSSTKTVLEHQ-----------------------PGQRGRKPGKKRGRT 284
E + EH+ RG + +
Sbjct: 362 LKQCGAEAAPQRCFPPLISEHEFKENMKLEAVNPILPEEVCVATITAVRGSYLWLQLEGS 421
Query: 285 PKTLISHPISAPSKTAEPLKFPKKRGPKPGSKRKPRTLLNPPPASPTTSTPEPDTSTVP- 343
K + +S S PL + + G + R+ R A P + TV
Sbjct: 422 KKPIPECIVSVESMDIFPLGWCETNGHPLSTPRRARVYKQRKIAVVQPEKQVPSSRTVHE 481
Query: 344 ----QDAATIPSSAMQAPTVC--IYLNKNGSTGPHLDKKKVQQLPDHFGPARASVVLQQA 397
Q+ + S + C IY N +GP+L+K ++ +LP GP +VL++
Sbjct: 482 GLRNQELNSTESVMINGKYCCPKIYFNHRCFSGPYLNKGRIAELPQCVGPGNCVLVLREV 541
Query: 398 VQACIDCAYHQKTVFSFLKQG-----HG-GEVISAVFDREQHTLNLPAVNSITYVLRFLE 451
+ I+ AY V L+ HG GEV+ A + + + + V + V F
Sbjct: 542 LTLLINAAYKPSRVLRELQLDKDSVWHGCGEVLKAKYKGKSYRATVEIVKTADRVTEFCR 601
Query: 452 KLCHNLRS-DNLFGNQPF----TQTHLSLTAIEYSHSHDRYL-------PGETFVLGNSL 499
+ C L NLFG + ++ LT +Y+H + + PG L +L
Sbjct: 602 QTCIKLECCPNLFGPRMVLDKCSENCSVLTKTKYTHYYGKKKNKRIGRPPGGHSNLACAL 661
Query: 500 ARSLEPHSDSMDSASNPTNLVSTSQRHRPLLSSCG------------------------- 534
++ + + + S S + P S G
Sbjct: 662 KKASKRRKRRKNVFVHKKKRSSASVDNTPAGSPQGSGGEDEDDPDEGDDDSLSEGSTSEQ 721
Query: 535 ---LPPSTASAVRRLCSRGV--------LKGSNERRDME----SFWKLNRSPGSDRYLES 579
L + + ++ CS L +RR E SF P S + +
Sbjct: 722 QDELQEESEMSEKKSCSSSPTQSEISTSLPPDRQRRKRELRTFSFSDDENKPPSPKEIRI 781
Query: 580 RDASRLS-GRDPSSWTVEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRSDMMMKYM 638
A RL +P W+V DV++F+R D P A +F EIDG+ALLLL + + M
Sbjct: 782 EVAERLHLDSNPLKWSVADVVRFIRSTD--CAPLARIFLDQEIDGQALLLLTLPTVQECM 839
Query: 639 GLKLGPALKLSYHIDRLK 656
LKLGPA+KL +HI+R+K
Sbjct: 840 DLKLGPAIKLCHHIERIK 857
Score = 92.4 bits (228), Expect = 1e-18
Identities = 65/213 (30%), Positives = 99/213 (46%), Gaps = 7/213 (3%)
Query: 29 TWDKYLKETCSVPAPVHCFKQSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGARL 88
+W+ YL+ET S P FK T N F MKLE + + +ATV+ L
Sbjct: 21 SWEDYLEETGSTAVPYGSFKHVDTRLQNGFAPGMKLEVAVRTDPETYWVATVITTCEQLL 80
Query: 89 RLRLDG--SDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLGFRLNASSWPMFLLKTLNG 146
LR DG D + DFW + A++ PIG CE+N L+ P G R S W FL +TL G
Sbjct: 81 LLRYDGYGEDRRADFWCDIRKADLYPIGWCEQNKKTLEAPEGIRDKVSDWDEFLRQTLIG 140
Query: 147 AEMAPIRIFH--KEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFDGW 204
A P+ + + +P + G +LE ++ T+ E G + + ++G
Sbjct: 141 ACSPPVPLLEGLRNGRNPL-DLIAPGSRLECQAFQDSLSTWIVTVVENIGGRLKLRYEGL 199
Query: 205 RGA--FDYWCRFDSRDIFPVGWCSLTGDNLQPP 235
+ +++W + + VGW + G LQPP
Sbjct: 200 ESSDNYEHWLYYLDPFLHHVGWAAQQGYELQPP 232
Score = 64.7 bits (156), Expect = 3e-10
Identities = 42/109 (38%), Positives = 57/109 (52%), Gaps = 9/109 (8%)
Query: 22 GSPLGHFTWDKYLKETCSVPAPVHCFKQSYTPP---SNEFKISMKLEAQDPRNTTSTCIA 78
G P F W YLK+ + AP CF PP +EFK +MKLEA +P C+A
Sbjct: 350 GYPSQDFDWADYLKQCGAEAAPQRCF-----PPLISEHEFKENMKLEAVNPILPEEVCVA 404
Query: 79 TVVGLTGARLRLRLDGSDNK-NDFWRLVDSAEIQPIGNCEKNGGMLQPP 126
T+ + G+ L L+L+GS + V+S +I P+G CE NG L P
Sbjct: 405 TITAVRGSYLWLQLEGSKKPIPECIVSVESMDIFPLGWCETNGHPLSTP 453
>gi|53692191 Scm-like with four mbt domains 1 [Homo sapiens]
Length = 866
Score = 148 bits (373), Expect = 2e-35
Identities = 183/738 (24%), Positives = 285/738 (38%), Gaps = 121/738 (16%)
Query: 30 WDKYLKET----CSVPAPVHCFKQSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTG 85
WD++L++T CS P P+ ++ P + +LE Q +++ ST I TVV G
Sbjct: 130 WDEFLRQTLIGACSPPVPLLEGLRNGRNPLDLIAPGSRLECQAFQDSLSTWIVTVVENIG 189
Query: 86 ARLRLRLDGSDNKNDF--WRLVDSAEIQPIGNCEKNGGMLQPPLGFR--LNASSWPMFLL 141
RL+LR +G ++ +++ W + +G + G LQPP R N + W L
Sbjct: 190 GRLKLRYEGLESSDNYEHWLYYLDPFLHHVGWAAQQGYELQPPSAIRHLKNEAEWQEILA 249
Query: 142 KTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEV-LVT 200
K E K+ + F + MKLEAVD +P I PAT+ +V + LV
Sbjct: 250 KVKEEEEEPLPSYLFKDKQVIGIHTFSVNMKLEAVDPWSPFGISPATVVKVFDEKYFLVE 309
Query: 201 FDGWR----GAFDYWCRFDSRDIFPVGWCSLTGDNLQPPGTKVVIPKNPYPASDVN---- 252
D R + C DS IFPV W G ++ PP YP+ D +
Sbjct: 310 MDDLRPENHARRSFVCHADSPGIFPVQWSLKNGLHISPPPG--------YPSQDFDWADY 361
Query: 253 -----TEKPSIHSSTKTVLEHQ-----------------------PGQRGRKPGKKRGRT 284
E + EH+ RG + +
Sbjct: 362 LKQCGAEAAPQRCFPPLISEHEFKENMKLEAVNPILPEEVCVATITAVRGSYLWLQLEGS 421
Query: 285 PKTLISHPISAPSKTAEPLKFPKKRGPKPGSKRKPRTLLNPPPASPTTSTPEPDTSTVP- 343
K + +S S PL + + G + R+ R A P + TV
Sbjct: 422 KKPIPECIVSVESMDIFPLGWCETNGHPLSTPRRARVYKQRKIAVVQPEKQVPSSRTVHE 481
Query: 344 ----QDAATIPSSAMQAPTVC--IYLNKNGSTGPHLDKKKVQQLPDHFGPARASVVLQQA 397
Q+ + S + C IY N +GP+L+K ++ +LP GP +VL++
Sbjct: 482 GLRNQELNSTESVMINGKYCCPKIYFNHRCFSGPYLNKGRIAELPQCVGPGNCVLVLREV 541
Query: 398 VQACIDCAYHQKTVFSFLKQG-----HG-GEVISAVFDREQHTLNLPAVNSITYVLRFLE 451
+ I+ AY V L+ HG GEV+ A + + + + V + V F
Sbjct: 542 LTLLINAAYKPSRVLRELQLDKDSVWHGCGEVLKAKYKGKSYRATVEIVKTADRVTEFCR 601
Query: 452 KLCHNLRS-DNLFGNQPF----TQTHLSLTAIEYSHSHDRYL-------PGETFVLGNSL 499
+ C L NLFG + ++ LT +Y+H + + PG L +L
Sbjct: 602 QTCIKLECCPNLFGPRMVLDKCSENCSVLTKTKYTHYYGKKKNKRIGRPPGGHSNLACAL 661
Query: 500 ARSLEPHSDSMDSASNPTNLVSTSQRHRPLLSSCG------------------------- 534
++ + + + S S + P S G
Sbjct: 662 KKASKRRKRRKNVFVHKKKRSSASVDNTPAGSPQGSGGEDEDDPDEGDDDSLSEGSTSEQ 721
Query: 535 ---LPPSTASAVRRLCSRGV--------LKGSNERRDME----SFWKLNRSPGSDRYLES 579
L + + ++ CS L +RR E SF P S + +
Sbjct: 722 QDELQEESEMSEKKSCSSSPTQSEISTSLPPDRQRRKRELRTFSFSDDENKPPSPKEIRI 781
Query: 580 RDASRLS-GRDPSSWTVEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRSDMMMKYM 638
A RL +P W+V DV++F+R D P A +F EIDG+ALLLL + + M
Sbjct: 782 EVAERLHLDSNPLKWSVADVVRFIRSTD--CAPLARIFLDQEIDGQALLLLTLPTVQECM 839
Query: 639 GLKLGPALKLSYHIDRLK 656
LKLGPA+KL +HI+R+K
Sbjct: 840 DLKLGPAIKLCHHIERIK 857
Score = 92.4 bits (228), Expect = 1e-18
Identities = 65/213 (30%), Positives = 99/213 (46%), Gaps = 7/213 (3%)
Query: 29 TWDKYLKETCSVPAPVHCFKQSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGARL 88
+W+ YL+ET S P FK T N F MKLE + + +ATV+ L
Sbjct: 21 SWEDYLEETGSTAVPYGSFKHVDTRLQNGFAPGMKLEVAVRTDPETYWVATVITTCEQLL 80
Query: 89 RLRLDG--SDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLGFRLNASSWPMFLLKTLNG 146
LR DG D + DFW + A++ PIG CE+N L+ P G R S W FL +TL G
Sbjct: 81 LLRYDGYGEDRRADFWCDIRKADLYPIGWCEQNKKTLEAPEGIRDKVSDWDEFLRQTLIG 140
Query: 147 AEMAPIRIFH--KEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFDGW 204
A P+ + + +P + G +LE ++ T+ E G + + ++G
Sbjct: 141 ACSPPVPLLEGLRNGRNPL-DLIAPGSRLECQAFQDSLSTWIVTVVENIGGRLKLRYEGL 199
Query: 205 RGA--FDYWCRFDSRDIFPVGWCSLTGDNLQPP 235
+ +++W + + VGW + G LQPP
Sbjct: 200 ESSDNYEHWLYYLDPFLHHVGWAAQQGYELQPP 232
Score = 64.7 bits (156), Expect = 3e-10
Identities = 42/109 (38%), Positives = 57/109 (52%), Gaps = 9/109 (8%)
Query: 22 GSPLGHFTWDKYLKETCSVPAPVHCFKQSYTPP---SNEFKISMKLEAQDPRNTTSTCIA 78
G P F W YLK+ + AP CF PP +EFK +MKLEA +P C+A
Sbjct: 350 GYPSQDFDWADYLKQCGAEAAPQRCF-----PPLISEHEFKENMKLEAVNPILPEEVCVA 404
Query: 79 TVVGLTGARLRLRLDGSDNK-NDFWRLVDSAEIQPIGNCEKNGGMLQPP 126
T+ + G+ L L+L+GS + V+S +I P+G CE NG L P
Sbjct: 405 TITAVRGSYLWLQLEGSKKPIPECIVSVESMDIFPLGWCETNGHPLSTP 453
>gi|53692195 Scm-like with four mbt domains 1 [Homo sapiens]
Length = 866
Score = 148 bits (373), Expect = 2e-35
Identities = 183/738 (24%), Positives = 285/738 (38%), Gaps = 121/738 (16%)
Query: 30 WDKYLKET----CSVPAPVHCFKQSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTG 85
WD++L++T CS P P+ ++ P + +LE Q +++ ST I TVV G
Sbjct: 130 WDEFLRQTLIGACSPPVPLLEGLRNGRNPLDLIAPGSRLECQAFQDSLSTWIVTVVENIG 189
Query: 86 ARLRLRLDGSDNKNDF--WRLVDSAEIQPIGNCEKNGGMLQPPLGFR--LNASSWPMFLL 141
RL+LR +G ++ +++ W + +G + G LQPP R N + W L
Sbjct: 190 GRLKLRYEGLESSDNYEHWLYYLDPFLHHVGWAAQQGYELQPPSAIRHLKNEAEWQEILA 249
Query: 142 KTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEV-LVT 200
K E K+ + F + MKLEAVD +P I PAT+ +V + LV
Sbjct: 250 KVKEEEEEPLPSYLFKDKQVIGIHTFSVNMKLEAVDPWSPFGISPATVVKVFDEKYFLVE 309
Query: 201 FDGWR----GAFDYWCRFDSRDIFPVGWCSLTGDNLQPPGTKVVIPKNPYPASDVN---- 252
D R + C DS IFPV W G ++ PP YP+ D +
Sbjct: 310 MDDLRPENHARRSFVCHADSPGIFPVQWSLKNGLHISPPPG--------YPSQDFDWADY 361
Query: 253 -----TEKPSIHSSTKTVLEHQ-----------------------PGQRGRKPGKKRGRT 284
E + EH+ RG + +
Sbjct: 362 LKQCGAEAAPQRCFPPLISEHEFKENMKLEAVNPILPEEVCVATITAVRGSYLWLQLEGS 421
Query: 285 PKTLISHPISAPSKTAEPLKFPKKRGPKPGSKRKPRTLLNPPPASPTTSTPEPDTSTVP- 343
K + +S S PL + + G + R+ R A P + TV
Sbjct: 422 KKPIPECIVSVESMDIFPLGWCETNGHPLSTPRRARVYKQRKIAVVQPEKQVPSSRTVHE 481
Query: 344 ----QDAATIPSSAMQAPTVC--IYLNKNGSTGPHLDKKKVQQLPDHFGPARASVVLQQA 397
Q+ + S + C IY N +GP+L+K ++ +LP GP +VL++
Sbjct: 482 GLRNQELNSTESVMINGKYCCPKIYFNHRCFSGPYLNKGRIAELPQCVGPGNCVLVLREV 541
Query: 398 VQACIDCAYHQKTVFSFLKQG-----HG-GEVISAVFDREQHTLNLPAVNSITYVLRFLE 451
+ I+ AY V L+ HG GEV+ A + + + + V + V F
Sbjct: 542 LTLLINAAYKPSRVLRELQLDKDSVWHGCGEVLKAKYKGKSYRATVEIVKTADRVTEFCR 601
Query: 452 KLCHNLRS-DNLFGNQPF----TQTHLSLTAIEYSHSHDRYL-------PGETFVLGNSL 499
+ C L NLFG + ++ LT +Y+H + + PG L +L
Sbjct: 602 QTCIKLECCPNLFGPRMVLDKCSENCSVLTKTKYTHYYGKKKNKRIGRPPGGHSNLACAL 661
Query: 500 ARSLEPHSDSMDSASNPTNLVSTSQRHRPLLSSCG------------------------- 534
++ + + + S S + P S G
Sbjct: 662 KKASKRRKRRKNVFVHKKKRSSASVDNTPAGSPQGSGGEDEDDPDEGDDDSLSEGSTSEQ 721
Query: 535 ---LPPSTASAVRRLCSRGV--------LKGSNERRDME----SFWKLNRSPGSDRYLES 579
L + + ++ CS L +RR E SF P S + +
Sbjct: 722 QDELQEESEMSEKKSCSSSPTQSEISTSLPPDRQRRKRELRTFSFSDDENKPPSPKEIRI 781
Query: 580 RDASRLS-GRDPSSWTVEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRSDMMMKYM 638
A RL +P W+V DV++F+R D P A +F EIDG+ALLLL + + M
Sbjct: 782 EVAERLHLDSNPLKWSVADVVRFIRSTD--CAPLARIFLDQEIDGQALLLLTLPTVQECM 839
Query: 639 GLKLGPALKLSYHIDRLK 656
LKLGPA+KL +HI+R+K
Sbjct: 840 DLKLGPAIKLCHHIERIK 857
Score = 92.4 bits (228), Expect = 1e-18
Identities = 65/213 (30%), Positives = 99/213 (46%), Gaps = 7/213 (3%)
Query: 29 TWDKYLKETCSVPAPVHCFKQSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGARL 88
+W+ YL+ET S P FK T N F MKLE + + +ATV+ L
Sbjct: 21 SWEDYLEETGSTAVPYGSFKHVDTRLQNGFAPGMKLEVAVRTDPETYWVATVITTCEQLL 80
Query: 89 RLRLDG--SDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLGFRLNASSWPMFLLKTLNG 146
LR DG D + DFW + A++ PIG CE+N L+ P G R S W FL +TL G
Sbjct: 81 LLRYDGYGEDRRADFWCDIRKADLYPIGWCEQNKKTLEAPEGIRDKVSDWDEFLRQTLIG 140
Query: 147 AEMAPIRIFH--KEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFDGW 204
A P+ + + +P + G +LE ++ T+ E G + + ++G
Sbjct: 141 ACSPPVPLLEGLRNGRNPL-DLIAPGSRLECQAFQDSLSTWIVTVVENIGGRLKLRYEGL 199
Query: 205 RGA--FDYWCRFDSRDIFPVGWCSLTGDNLQPP 235
+ +++W + + VGW + G LQPP
Sbjct: 200 ESSDNYEHWLYYLDPFLHHVGWAAQQGYELQPP 232
Score = 64.7 bits (156), Expect = 3e-10
Identities = 42/109 (38%), Positives = 57/109 (52%), Gaps = 9/109 (8%)
Query: 22 GSPLGHFTWDKYLKETCSVPAPVHCFKQSYTPP---SNEFKISMKLEAQDPRNTTSTCIA 78
G P F W YLK+ + AP CF PP +EFK +MKLEA +P C+A
Sbjct: 350 GYPSQDFDWADYLKQCGAEAAPQRCF-----PPLISEHEFKENMKLEAVNPILPEEVCVA 404
Query: 79 TVVGLTGARLRLRLDGSDNK-NDFWRLVDSAEIQPIGNCEKNGGMLQPP 126
T+ + G+ L L+L+GS + V+S +I P+G CE NG L P
Sbjct: 405 TITAVRGSYLWLQLEGSKKPIPECIVSVESMDIFPLGWCETNGHPLSTP 453
>gi|158508476 mbt domain containing 1 [Homo sapiens]
Length = 628
Score = 130 bits (327), Expect = 4e-30
Identities = 85/241 (35%), Positives = 120/241 (49%), Gaps = 22/241 (9%)
Query: 15 DLPCSIMGSPLGHFTWDKYL-----------KETCSVPAPVHCF-KQSYTPPSNE-FKIS 61
D C + + H W + + K+ P H F K S E FK
Sbjct: 328 DFWCHMHSPLIHHIGWSRSIGHRFKRSDITKKQDGHFDTPPHLFAKVKEVDQSGEWFKEG 387
Query: 62 MKLEAQDPRNTTSTCIATVVG-LTGARLRLRLDGS---DNKNDFWRLVDSAEIQPIGNCE 117
MKLEA DP N ++ C+AT+ L L + +DGS D + F S I P+G CE
Sbjct: 388 MKLEAIDPLNLSTICVATIRKVLADGFLMIGIDGSEAADGSDWFCYHATSPSIFPVGFCE 447
Query: 118 KNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKLEAVD 177
N L PP G+ W +L +T G+ AP+++F+K+ P+ F++GMKLEAVD
Sbjct: 448 INMIELTPPRGYTKLPFKWFDYLRET--GSIAAPVKLFNKDVPNHG---FRVGMKLEAVD 502
Query: 178 RKNPHFICPATIGEVRGSEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQPPGT 237
P IC AT+ + + + FDGW +D W +S D++PVGWC LTG LQPP +
Sbjct: 503 LMEPRLICVATVTRIIHRLLRIHFDGWEEEYDQWVDCESPDLYPVGWCQLTGYQLQPPAS 562
Query: 238 K 238
+
Sbjct: 563 Q 563
Score = 83.2 bits (204), Expect = 7e-16
Identities = 63/211 (29%), Positives = 95/211 (45%), Gaps = 12/211 (5%)
Query: 28 FTWDKYLKETCSVPAPVHCFKQSYTPPSNEF-KISMKLEAQDPRNTTST-----CIATVV 81
F+W Y+ + APV CFK + P + IS + + P S IA +V
Sbjct: 141 FSWGNYINSNSFIAAPVTCFK--HAPMGTCWGDISENVRVEVPNTDCSLPTKVFWIAGIV 198
Query: 82 GLTGARLRLRLDGSDNKN--DFWRLVDSAEIQPIGNCEKNGGMLQPPLGFRLNASSWPMF 139
L G LR +G +N + DFW + ++I P+G C +G L PP + ++W F
Sbjct: 199 KLAGYNALLRYEGFENDSGLDFWCNICGSDIHPVGWCAASGKPLVPPRTIQHKYTNWKAF 258
Query: 140 LLKTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEV-L 198
L+K L GA+ P K S + FK M++E VD+++ A + V G + L
Sbjct: 259 LVKRLTGAKTLPPDFSQKVSESMQYP-FKPCMRVEVVDKRHLCRTRVAVVESVIGGRLRL 317
Query: 199 VTFDGWRGAFDYWCRFDSRDIFPVGWCSLTG 229
V + D+WC S I +GW G
Sbjct: 318 VYEESEDRTDDFWCHMHSPLIHHIGWSRSIG 348
Score = 72.8 bits (177), Expect = 1e-12
Identities = 64/191 (33%), Positives = 89/191 (46%), Gaps = 18/191 (9%)
Query: 58 FKISMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNK-NDFWRLVDSAEIQPIGNC 116
FK M++E D R+ T +A V + G RLRL + S+++ +DFW + S I IG
Sbjct: 285 FKPCMRVEVVDKRHLCRTRVAVVESVIGGRLRLVYEESEDRTDDFWCHMHSPLIHHIGWS 344
Query: 117 EKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIRIFHK-EPPSPSHNFFKMGMKLEA 175
+G R S + K +G P +F K + S +FK GMKLEA
Sbjct: 345 RS--------IGHRFKRSD----ITKKQDGHFDTPPHLFAKVKEVDQSGEWFKEGMKLEA 392
Query: 176 VDRKNPHFICPATIGEVRGSEVL-VTFDGWRGA--FDYWC-RFDSRDIFPVGWCSLTGDN 231
+D N IC ATI +V L + DG A D++C S IFPVG+C +
Sbjct: 393 IDPLNLSTICVATIRKVLADGFLMIGIDGSEAADGSDWFCYHATSPSIFPVGFCEINMIE 452
Query: 232 LQPPGTKVVIP 242
L PP +P
Sbjct: 453 LTPPRGYTKLP 463
Score = 45.1 bits (105), Expect = 2e-04
Identities = 20/53 (37%), Positives = 29/53 (54%), Gaps = 2/53 (3%)
Query: 187 ATIGEVRGSEVLVTFDGWRG--AFDYWCRFDSRDIFPVGWCSLTGDNLQPPGT 237
A I ++ G L+ ++G+ D+WC DI PVGWC+ +G L PP T
Sbjct: 195 AGIVKLAGYNALLRYEGFENDSGLDFWCNICGSDIHPVGWCAASGKPLVPPRT 247
>gi|20149698 l(3)mbt-like 2 [Homo sapiens]
Length = 705
Score = 129 bits (325), Expect = 7e-30
Identities = 100/292 (34%), Positives = 137/292 (46%), Gaps = 33/292 (11%)
Query: 58 FKISMKLEAQDPRNTTSTCIATVVG-LTGARLRLRLDG---SDNKNDFWRLVDSAEIQPI 113
F+ MKLEA DP N + C+ATV L L + +DG +D + F S I P
Sbjct: 428 FEEGMKLEAIDPLNLGNICVATVCKVLLDGYLMICVDGGPSTDGLDWFCYHASSHAIFPA 487
Query: 114 GNCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKL 173
C+KN L PP G+ +W +L KT + A AP R+F+ + P+H F K+GMKL
Sbjct: 488 TFCQKNDIELTPPKGYEAQTFNWENYLEKTKSKA--APSRLFNMD--CPNHGF-KVGMKL 542
Query: 174 EAVDRKNPHFICPATIGEVRGSEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQ 233
EAVD P IC AT+ V + + FDGW +D W +S DI+PVGWC LTG LQ
Sbjct: 543 EAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQLQ 602
Query: 234 PPGTKVVIPKNPYPASDVNTEKPSIHSSTKTVLEHQPGQRGRKPGKKRGRTPKTLISHPI 293
PP P P A + +K ++ GKKR R P T + P+
Sbjct: 603 PP--VAAEPATPLKAKEATKKKK------------------KQFGKKRKRIPPTK-TRPL 641
Query: 294 SAPSKTAEPLKFPKKRGP-KPGSKRKPRTLLNPPPASPTTSTPEPDTSTVPQ 344
SK +PL +G K S+ P ++ PD ++ P+
Sbjct: 642 RQGSK--KPLLEDDPQGARKISSEPVPGEIIAVRVKEEHLDVASPDKASSPE 691
Score = 98.2 bits (243), Expect = 2e-20
Identities = 66/226 (29%), Positives = 105/226 (46%), Gaps = 17/226 (7%)
Query: 22 GSPLGH------FTWDKYLKETCSVPAPVHCFKQSYTPPSNEFKISMKLEAQDPRNTTST 75
G+P G F W K+LK+ APV CFK + P ++++ MK + N+ +
Sbjct: 167 GTPTGQDALVLGFDWGKFLKDHSYKAAPVSCFK--HVPLYDQWEDVMKGMKVEVLNSDAV 224
Query: 76 C------IATVVGLTGARLRLRLDGSDN--KNDFWRLVDSAEIQPIGNCEKNGGMLQPPL 127
IA+V+ G R+ LR +G +N +DFW + + ++ PIG C N +L PP
Sbjct: 225 LPSRVYWIASVIQTAGYRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPPR 284
Query: 128 GFRLNASSWPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPA 187
+ W +L+K L G+ P+ FH + F+ GM+LE VD+ A
Sbjct: 285 TIHAKFTDWKGYLMKRLVGSRTLPVD-FHIKMVESMKYPFRQGMRLEVVDKSQVSRTRMA 343
Query: 188 TIGEVRGSEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQ 233
+ V G + + ++ D+WC S I PVGW G ++
Sbjct: 344 VVDTVIGGRLRLLYEDGDSDDDFWCHMWSPLIHPVGWSRRVGHGIK 389
Score = 72.8 bits (177), Expect = 1e-12
Identities = 39/100 (39%), Positives = 54/100 (54%), Gaps = 2/100 (2%)
Query: 28 FTWDKYLKETCSVPAPVHCFKQSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGAR 87
F W+ YL++T S AP F P++ FK+ MKLEA D C+ATV +
Sbjct: 508 FNWENYLEKTKSKAAPSRLFNMDC--PNHGFKVGMKLEAVDLMEPRLICVATVKRVVHRL 565
Query: 88 LRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPL 127
L + DG D++ D W +S +I P+G CE G LQPP+
Sbjct: 566 LSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQLQPPV 605
Score = 60.8 bits (146), Expect = 4e-09
Identities = 54/192 (28%), Positives = 81/192 (42%), Gaps = 28/192 (14%)
Query: 58 FKISMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIG--- 114
F+ M+LE D + T +A V + G RLRL + D+ +DFW + S I P+G
Sbjct: 323 FRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLYEDGDSDDDFWCHMWSPLIHPVGWSR 382
Query: 115 -------NCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFF 167
E+ M P ++ + P K +R + E +F
Sbjct: 383 RVGHGIKMSERRSDMAHHPTFRKIYCDAVPYLFKK---------VRAVYTEG-----GWF 428
Query: 168 KMGMKLEAVDRKNPHFICPATIGEV-RGSEVLVTFDGW--RGAFDYWC-RFDSRDIFPVG 223
+ GMKLEA+D N IC AT+ +V +++ DG D++C S IFP
Sbjct: 429 EEGMKLEAIDPLNLGNICVATVCKVLLDGYLMICVDGGPSTDGLDWFCYHASSHAIFPAT 488
Query: 224 WCSLTGDNLQPP 235
+C L PP
Sbjct: 489 FCQKNDIELTPP 500
Score = 48.9 bits (115), Expect = 1e-05
Identities = 30/110 (27%), Positives = 50/110 (45%), Gaps = 13/110 (11%)
Query: 136 WPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICP------ATI 189
W FL + + AP+ F P GMK+E + N + P A++
Sbjct: 181 WGKFLKD--HSYKAAPVSCFKHVPLYDQWEDVMKGMKVEVL---NSDAVLPSRVYWIASV 235
Query: 190 GEVRGSEVLVTFDGWRG--AFDYWCRFDSRDIFPVGWCSLTGDNLQPPGT 237
+ G VL+ ++G+ + D+WC + D+ P+GWC++ L PP T
Sbjct: 236 IQTAGYRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRT 285
>gi|71274154 Scm-like with four mbt domains 2 [Homo sapiens]
Length = 894
Score = 96.3 bits (238), Expect = 8e-20
Identities = 110/475 (23%), Positives = 180/475 (37%), Gaps = 81/475 (17%)
Query: 54 PSNEFKISMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDF--WRLVDSAEIQ 111
P + + +E QD +N I +V+ G RLRLR G ++ + W ++
Sbjct: 182 PIDLITVGSLIELQDSQNPFQYWIVSVIENVGGRLRLRYVGLEDTESYDQWLFYLDYRLR 241
Query: 112 PIGNCEKNGGMLQPPLGFR--LNASSWPMFLLKTLNGAEMAPI--RIFHKEPPSPSHNFF 167
P+G C++N + PP AS W L K+L A P+ +F SH FF
Sbjct: 242 PVGWCQENKYRMDPPSEIYPLKMASEWKCTLEKSLIDAAKFPLPMEVFKDHADLRSH-FF 300
Query: 168 KMGMKLEAVDRKNPHFICPATIGEVRGSEVL-VTFDGWR---GAFDYWCRFDSRDIFPVG 223
+GMKLE V+ P +I PA++ +V + VT D R C DS I PV
Sbjct: 301 TVGMKLETVNMCEPFYISPASVTKVFNNHFFQVTIDDLRPEPSKLSMLCHADSLGILPVQ 360
Query: 224 WCSLTGDNLQPPGTKVVIPKNPYPASDVN----TEKPSIHSSTKTVLEHQPGQRG----- 274
WC G +L PP Y D + ++ + + RG
Sbjct: 361 WCLKNGVSLTPP--------KGYSGQDFDWADYHKQHGAQEAPPFCFRNTSFSRGFTKNM 412
Query: 275 -------RKPGK--------KRGR------------TPKTLIS------HPISAPSKTAE 301
R PG+ +GR P+ ++ P+ +
Sbjct: 413 KLEAVNPRNPGELCVASVVSVKGRLMWLHLEGLQTPVPEVIVDVESMDIFPVGWCEANSY 472
Query: 302 PLKFPKKRGPKPGSKRKPRTLLNPPPASPTTSTPEPDTSTVPQDAATIP----SSAMQAP 357
PL P K K++ ++ P P P +P D P + +
Sbjct: 473 PLTAPHK---TVSQKKRKIAVVQPEKQLP----PTVPVKKIPHDLCLFPHLDTTGTVNGK 525
Query: 358 TVC--IYLNKNGSTGPHLDKKKVQQLPDHFGPARASVVLQQAVQACIDCAYHQKTV---F 412
C +++N +GP+L+K ++ +LP GP + +VL++ + I+ AY V
Sbjct: 526 YCCPQLFINHRCFSGPYLNKGRIAELPQSVGPGKCVLVLKEVLSMIINAAYKPGRVLREL 585
Query: 413 SFLKQGHGG---EVISAVFDREQHTLNLPAVNSITYVLRFLEKLCHNLR-SDNLF 463
++ H E + A + + + + V + V F ++C L NLF
Sbjct: 586 QLVEDPHWNFQEETLKAKYRGKTYRAVVKIVRTSDQVANFCRRVCAKLECCPNLF 640
Score = 95.5 bits (236), Expect = 1e-19
Identities = 62/215 (28%), Positives = 98/215 (45%), Gaps = 9/215 (4%)
Query: 28 FTWDKYLKETCSVPAPVHCFKQSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGAR 87
F W +YL+ET + AP FK + F+ MKLE + N + +AT++ G
Sbjct: 44 FNWGEYLEETGASAAPHTSFKHVEISIQSNFQPGMKLEVANKNNPDTYWVATIITTCGQL 103
Query: 88 LRLRLDG--SDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLGFRLNASSWPMFLLKTLN 145
L LR G D + DFW V A++ P+G C +N +L PP + + W FL++ L
Sbjct: 104 LLLRYCGYGEDRRADFWCDVVIADLHPVGWCTQNNKVLMPPDAIKEKYTDWTEFLIRDLT 163
Query: 146 GAEMAPIRIFHKEPPSPSH---NFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFD 202
G+ AP + E P + +G +E D +NP ++ E G + + +
Sbjct: 164 GSRTAPANLL--EGPLRGKGPIDLITVGSLIELQDSQNPFQYWIVSVIENVGGRLRLRYV 221
Query: 203 GWRG--AFDYWCRFDSRDIFPVGWCSLTGDNLQPP 235
G ++D W + + PVGWC + PP
Sbjct: 222 GLEDTESYDQWLFYLDYRLRPVGWCQENKYRMDPP 256
Score = 69.3 bits (168), Expect = 1e-11
Identities = 63/212 (29%), Positives = 93/212 (43%), Gaps = 10/212 (4%)
Query: 29 TWDKYLKETCSVPAPVHCFKQSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGARL 88
T +K L + P P+ FK S+ F + MKLE + A+V +
Sbjct: 271 TLEKSLIDAAKFPLPMEVFKDHADLRSHFFTVGMKLETVNMCEPFYISPASVTKVFNNHF 330
Query: 89 -RLRLDG---SDNKNDFWRLVDSAEIQPIGNCEKNGGMLQPPLGFRLNASSWPMFLLKTL 144
++ +D +K DS I P+ C KNG L PP G+ W + +
Sbjct: 331 FQVTIDDLRPEPSKLSMLCHADSLGILPVQWCLKNGVSLTPPKGYSGQDFDWADYHKQ-- 388
Query: 145 NGAEMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFDGW 204
+GA+ AP F S S F K MKLEAV+ +NP +C A++ V+G + + +G
Sbjct: 389 HGAQEAPPFCFRNT--SFSRGFTK-NMKLEAVNPRNPGELCVASVVSVKGRLMWLHLEGL 445
Query: 205 RGAF-DYWCRFDSRDIFPVGWCSLTGDNLQPP 235
+ + +S DIFPVGWC L P
Sbjct: 446 QTPVPEVIVDVESMDIFPVGWCEANSYPLTAP 477
Score = 62.4 bits (150), Expect = 1e-09
Identities = 31/68 (45%), Positives = 47/68 (69%), Gaps = 2/68 (2%)
Query: 589 DPSSWTVEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKL 648
+P WTV DV++F++ D P A +F++ +IDG+ALLLL + + M LKLGPA+KL
Sbjct: 820 NPLEWTVTDVVRFIKLTD--CAPLAKIFQEQDIDGQALLLLTLPTVQECMELKLGPAIKL 877
Query: 649 SYHIDRLK 656
+ I+R+K
Sbjct: 878 CHQIERVK 885
Score = 56.2 bits (134), Expect = 9e-08
Identities = 37/100 (37%), Positives = 51/100 (51%), Gaps = 3/100 (3%)
Query: 28 FTWDKYLKETCSVPAPVHCFKQSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGAR 87
F W Y K+ + AP CF+ T S F +MKLEA +PRN C+A+VV + G
Sbjct: 380 FDWADYHKQHGAQEAPPFCFRN--TSFSRGFTKNMKLEAVNPRNPGELCVASVVSVKGRL 437
Query: 88 LRLRLDGSDNK-NDFWRLVDSAEIQPIGNCEKNGGMLQPP 126
+ L L+G + V+S +I P+G CE N L P
Sbjct: 438 MWLHLEGLQTPVPEVIVDVESMDIFPVGWCEANSYPLTAP 477
>gi|82830432 sex comb on midleg-like 1 isoform a [Homo sapiens]
Length = 329
Score = 95.9 bits (237), Expect = 1e-19
Identities = 51/95 (53%), Positives = 70/95 (73%), Gaps = 6/95 (6%)
Query: 567 LNRSP-GSDRYLESRDASRLSGRDPSSWTVEDVMQFVREADP-QLGPHADLFRKHEIDGK 624
+ RSP +D Y+E ++ PS+W+VE V+ F+++ DP L P DLFR HEIDGK
Sbjct: 235 VTRSPVENDGYIEEGSITK----HPSTWSVEAVVLFLKQTDPLALCPLVDLFRSHEIDGK 290
Query: 625 ALLLLRSDMMMKYMGLKLGPALKLSYHIDRLKQGK 659
ALLLL SD+++K++G+KLG A+KL Y+IDRLKQGK
Sbjct: 291 ALLLLTSDVLLKHLGVKLGTAVKLCYYIDRLKQGK 325
>gi|82830436 sex comb on midleg-like 1 isoform c [Homo sapiens]
Length = 208
Score = 95.9 bits (237), Expect = 1e-19
Identities = 51/95 (53%), Positives = 70/95 (73%), Gaps = 6/95 (6%)
Query: 567 LNRSP-GSDRYLESRDASRLSGRDPSSWTVEDVMQFVREADP-QLGPHADLFRKHEIDGK 624
+ RSP +D Y+E ++ PS+W+VE V+ F+++ DP L P DLFR HEIDGK
Sbjct: 114 VTRSPVENDGYIEEGSITK----HPSTWSVEAVVLFLKQTDPLALCPLVDLFRSHEIDGK 169
Query: 625 ALLLLRSDMMMKYMGLKLGPALKLSYHIDRLKQGK 659
ALLLL SD+++K++G+KLG A+KL Y+IDRLKQGK
Sbjct: 170 ALLLLTSDVLLKHLGVKLGTAVKLCYYIDRLKQGK 204
>gi|82830430 sex comb on midleg-like 1 isoform c [Homo sapiens]
Length = 208
Score = 95.9 bits (237), Expect = 1e-19
Identities = 51/95 (53%), Positives = 70/95 (73%), Gaps = 6/95 (6%)
Query: 567 LNRSP-GSDRYLESRDASRLSGRDPSSWTVEDVMQFVREADP-QLGPHADLFRKHEIDGK 624
+ RSP +D Y+E ++ PS+W+VE V+ F+++ DP L P DLFR HEIDGK
Sbjct: 114 VTRSPVENDGYIEEGSITK----HPSTWSVEAVVLFLKQTDPLALCPLVDLFRSHEIDGK 169
Query: 625 ALLLLRSDMMMKYMGLKLGPALKLSYHIDRLKQGK 659
ALLLL SD+++K++G+KLG A+KL Y+IDRLKQGK
Sbjct: 170 ALLLLTSDVLLKHLGVKLGTAVKLCYYIDRLKQGK 204
>gi|82830426 sex comb on midleg-like 1 isoform b [Homo sapiens]
Length = 302
Score = 95.9 bits (237), Expect = 1e-19
Identities = 51/95 (53%), Positives = 70/95 (73%), Gaps = 6/95 (6%)
Query: 567 LNRSP-GSDRYLESRDASRLSGRDPSSWTVEDVMQFVREADP-QLGPHADLFRKHEIDGK 624
+ RSP +D Y+E ++ PS+W+VE V+ F+++ DP L P DLFR HEIDGK
Sbjct: 208 VTRSPVENDGYIEEGSITK----HPSTWSVEAVVLFLKQTDPLALCPLVDLFRSHEIDGK 263
Query: 625 ALLLLRSDMMMKYMGLKLGPALKLSYHIDRLKQGK 659
ALLLL SD+++K++G+KLG A+KL Y+IDRLKQGK
Sbjct: 264 ALLLLTSDVLLKHLGVKLGTAVKLCYYIDRLKQGK 298
>gi|148612879 polyhomeotic like 3 [Homo sapiens]
Length = 995
Score = 68.6 bits (166), Expect = 2e-11
Identities = 37/80 (46%), Positives = 50/80 (62%), Gaps = 1/80 (1%)
Query: 578 ESRDASRLSGRDPSSWTVEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRSDMMMKY 637
E+ D ++ +PS WTV+DV F+ P AD FR EIDG+ALLLL+ D +M
Sbjct: 916 ENSDLLPVAQTEPSIWTVDDVWAFIHSL-PGCQDIADEFRAQEIDGQALLLLKEDHLMSA 974
Query: 638 MGLKLGPALKLSYHIDRLKQ 657
M +KLGPALK+ I+ LK+
Sbjct: 975 MNIKLGPALKICARINSLKE 994
>gi|37595530 polyhomeotic-like 2 isoform b [Homo sapiens]
Length = 323
Score = 65.5 bits (158), Expect = 2e-10
Identities = 34/68 (50%), Positives = 44/68 (64%), Gaps = 1/68 (1%)
Query: 589 DPSSWTVEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKL 648
+P+ W VEDV +F+R P A+ FR EIDG+ALLLL+ D +M M +KLGPALK+
Sbjct: 255 EPTKWNVEDVYEFIRSL-PGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKI 313
Query: 649 SYHIDRLK 656
I LK
Sbjct: 314 YARISMLK 321
>gi|37595528 polyhomeotic-like 2 isoform a [Homo sapiens]
Length = 858
Score = 65.5 bits (158), Expect = 2e-10
Identities = 34/68 (50%), Positives = 44/68 (64%), Gaps = 1/68 (1%)
Query: 589 DPSSWTVEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKL 648
+P+ W VEDV +F+R P A+ FR EIDG+ALLLL+ D +M M +KLGPALK+
Sbjct: 790 EPTKWNVEDVYEFIRSL-PGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKI 848
Query: 649 SYHIDRLK 656
I LK
Sbjct: 849 YARISMLK 856
Score = 32.3 bits (72), Expect = 1.4
Identities = 33/129 (25%), Positives = 53/129 (41%), Gaps = 16/129 (12%)
Query: 245 PYPASDVNTEKPSIHSSTKTVLEH--QPGQRG----RKPGKKRGR-----TPKTLISHPI 293
P PA NT + S + + + +P ++G PG GR T + +HP+
Sbjct: 263 PTPAQSRNTAQASPAGAKPGIADSVMEPHKKGDGNSSVPGSMEGRAGLSRTVPAVAAHPL 322
Query: 294 SAPSKTAEPLKFPKKRGPKPGSKR-KPRTLLNPPPASPTTSTPEPDTSTVPQDAATIPSS 352
AP+ P + P+P SK +P+ ++ P P P P S A P
Sbjct: 323 IAPAYAQLQ---PHQLLPQPSSKHLQPQFVIQQQP-QPQQQQPPPQQSRPVLQAEPHPQL 378
Query: 353 AMQAPTVCI 361
A +P+V +
Sbjct: 379 ASVSPSVAL 387
>gi|62953127 polyhomeotic 1-like [Homo sapiens]
Length = 1004
Score = 58.9 bits (141), Expect = 1e-08
Identities = 31/69 (44%), Positives = 45/69 (65%), Gaps = 1/69 (1%)
Query: 589 DPSSWTVEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKL 648
+PS W+VE+V +F+ A+ FR EIDG+ALLLL+ + +M M +KLGPALK+
Sbjct: 936 NPSRWSVEEVYEFIASLQG-CQEIAEEFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKI 994
Query: 649 SYHIDRLKQ 657
I+ LK+
Sbjct: 995 CAKINVLKE 1003
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 57.8 bits (138), Expect = 3e-08
Identities = 31/73 (42%), Positives = 47/73 (64%), Gaps = 3/73 (4%)
Query: 589 DPSSWTVEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKL 648
DP WTV DV+++ EA A F++ EIDGK+LLL++ ++ + ++LGPALK+
Sbjct: 458 DPVEWTVMDVVEYFTEAG--FPEQATAFQEQEIDGKSLLLMQRTDVLTGLSIRLGPALKI 515
Query: 649 -SYHIDRLKQGKF 660
+HI L+QG F
Sbjct: 516 YEHHIKVLQQGHF 528
Score = 41.2 bits (95), Expect = 0.003
Identities = 40/162 (24%), Positives = 55/162 (33%), Gaps = 10/162 (6%)
Query: 234 PPGTKVVIPKNPYPASDVNTEKPSIHSSTKTVLEHQPGQRG-RKPGKKRGRTPKTLISHP 292
PP T P P P + V P+ P G +PG + R P
Sbjct: 127 PPPT----PAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPP 182
Query: 293 ISAPSKTAEPLKFPKKRGPKPGSKRKPRTLLNP-PPASPTTSTPEPDTSTVPQDAATIPS 351
A P P++ P + R+P P PPA P P P P + + +
Sbjct: 183 APAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRA 242
Query: 352 SAMQAPT----VCIYLNKNGSTGPHLDKKKVQQLPDHFGPAR 389
P V YL +G G L + +VQ L + AR
Sbjct: 243 GGAARPVSLREVVRYLGGSGGAGGRLTRGRVQGLLEEEAAAR 284
>gi|32699038 sterile alpha motif domain containing 7 [Homo sapiens]
Length = 446
Score = 56.2 bits (134), Expect = 9e-08
Identities = 28/66 (42%), Positives = 39/66 (59%), Gaps = 1/66 (1%)
Query: 589 DPSSWTVEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKL 648
D WTV+DV F+R P +A +F+ H IDG+ L LL + + MGLKLGPALK+
Sbjct: 323 DIQKWTVDDVHSFIRSL-PGCSDYAQVFKDHAIDGETLPLLTEEHLRGTMGLKLGPALKI 381
Query: 649 SYHIDR 654
+ +
Sbjct: 382 QSQVSQ 387
>gi|197927257 sterile alpha motif domain containing 13 isoform 2
[Homo sapiens]
Length = 102
Score = 52.4 bits (124), Expect = 1e-06
Identities = 38/100 (38%), Positives = 56/100 (56%), Gaps = 14/100 (14%)
Query: 560 DMESFWKLNRSPGSDRYLESRDASRLSGR--DPSSWTVEDVMQFVREADPQLGPHADLFR 617
DME+ K N S G +E+ GR DP+ W V DV+ + R + A F+
Sbjct: 5 DMEN--KENGSVGVKNSMEN-------GRPPDPADWAVMDVVNYFRTVGFE--EQASAFQ 53
Query: 618 KHEIDGKALLLLRSDMMMKYMGLKLGPALKL-SYHIDRLK 656
+ EIDGK+LLL+ + ++ + LKLGPALK+ YH+ L+
Sbjct: 54 EQEIDGKSLLLMTRNDVLTGLQLKLGPALKIYEYHVKPLQ 93
>gi|197927255 sterile alpha motif domain containing 13 isoform 2
[Homo sapiens]
Length = 102
Score = 52.4 bits (124), Expect = 1e-06
Identities = 38/100 (38%), Positives = 56/100 (56%), Gaps = 14/100 (14%)
Query: 560 DMESFWKLNRSPGSDRYLESRDASRLSGR--DPSSWTVEDVMQFVREADPQLGPHADLFR 617
DME+ K N S G +E+ GR DP+ W V DV+ + R + A F+
Sbjct: 5 DMEN--KENGSVGVKNSMEN-------GRPPDPADWAVMDVVNYFRTVGFE--EQASAFQ 53
Query: 618 KHEIDGKALLLLRSDMMMKYMGLKLGPALKL-SYHIDRLK 656
+ EIDGK+LLL+ + ++ + LKLGPALK+ YH+ L+
Sbjct: 54 EQEIDGKSLLLMTRNDVLTGLQLKLGPALKIYEYHVKPLQ 93
>gi|58293756 sterile alpha motif domain containing 13 isoform 1
[Homo sapiens]
Length = 116
Score = 52.4 bits (124), Expect = 1e-06
Identities = 38/100 (38%), Positives = 56/100 (56%), Gaps = 14/100 (14%)
Query: 560 DMESFWKLNRSPGSDRYLESRDASRLSGR--DPSSWTVEDVMQFVREADPQLGPHADLFR 617
DME+ K N S G +E+ GR DP+ W V DV+ + R + A F+
Sbjct: 19 DMEN--KENGSVGVKNSMEN-------GRPPDPADWAVMDVVNYFRTVGFE--EQASAFQ 67
Query: 618 KHEIDGKALLLLRSDMMMKYMGLKLGPALKL-SYHIDRLK 656
+ EIDGK+LLL+ + ++ + LKLGPALK+ YH+ L+
Sbjct: 68 EQEIDGKSLLLMTRNDVLTGLQLKLGPALKIYEYHVKPLQ 107
>gi|76881819 sterile alpha motif domain containing 11 [Homo sapiens]
Length = 681
Score = 52.0 bits (123), Expect = 2e-06
Identities = 28/66 (42%), Positives = 39/66 (59%), Gaps = 1/66 (1%)
Query: 589 DPSSWTVEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKL 648
D + WTV+DV FV G + +FR+ IDG+ L LL + ++ MGLKLGPALK+
Sbjct: 539 DVTKWTVDDVCSFVGGLSG-CGEYTRVFREQGIDGETLPLLTEEHLLTNMGLKLGPALKI 597
Query: 649 SYHIDR 654
+ R
Sbjct: 598 RAQVAR 603
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 43.9 bits (102), Expect = 5e-04
Identities = 38/135 (28%), Positives = 49/135 (36%), Gaps = 13/135 (9%)
Query: 234 PPGTKVVIPKNPYPASDVNTEKPSIHSSTKTVLEHQPGQRGRKPGKK-------RGRTPK 286
P GT PK P P + + + T L+ +KP K +G T
Sbjct: 620 PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTST 679
Query: 287 TLISHPISAPSKTAEPLKFPKKRGPKPGSKRKPRTLLNPPPASPTTSTP----EPDTSTV 342
T + P +TA PK+ P K P T PPP + STP EP T
Sbjct: 680 TSDKPAPTTPKETAPTT--PKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHK 737
Query: 343 PQDAATIPSSAMQAP 357
D +T SA P
Sbjct: 738 SPDESTPELSAEPTP 752
Score = 38.1 bits (87), Expect = 0.026
Identities = 29/115 (25%), Positives = 46/115 (40%), Gaps = 6/115 (5%)
Query: 236 GTKVVIPKNPYPASDVNTEKPSIHSSTKTVLEHQPGQRGRKPGKKRGRTPKTLISHPISA 295
G + PK P P + + T T ++ P ++P ++ T P A
Sbjct: 207 GPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAP-TTPKEPAPTTTKSAPTTPKEP--A 263
Query: 296 PSKTAEPL-KFPKKRGPKPGSKRKPRTLLNPP--PASPTTSTPEPDTSTVPQDAA 347
P+ T EP PK+ P + P T + P P P +TP+ T P++ A
Sbjct: 264 PTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA 318
Score = 38.1 bits (87), Expect = 0.026
Identities = 39/155 (25%), Positives = 51/155 (32%), Gaps = 13/155 (8%)
Query: 234 PPGTKVVIPKNPYPASDVNTEKPSIHSSTKTVLEHQPGQRGRKPGKKRGRTPKTLISHPI 293
P K P P + T++PS T E P P + P T S P
Sbjct: 358 PTTPKEPAPTTPKEPAPTTTKEPS----PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 413
Query: 294 SAPSKTAEPLKFPKKRGPKPGSKRKPRTLLNPPPASPTTSTP-EPDTSTVPQDAATIPSS 352
+ + K P PK + P+ P P +TP EP +T + A T P
Sbjct: 414 TPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE 473
Query: 353 AMQAPTVCIYLNKNGSTGPHLDKKKVQQLPDHFGP 387
APT T P KK P+ P
Sbjct: 474 --PAPTT------PKETAPTTPKKLTPTTPEKLAP 500
Score = 36.6 bits (83), Expect = 0.076
Identities = 32/136 (23%), Positives = 46/136 (33%), Gaps = 12/136 (8%)
Query: 234 PPGTKVVIPKNPYPASDVNTEKPSIHSSTKTVLEHQPGQRGRKPGKKRGRTPKTLISHPI 293
P TK P P + T++P+ ++TK+ P K TPK
Sbjct: 264 PTTTKEPAPTTPKEPAPTTTKEPA-PTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTP 322
Query: 294 SAPSKTAEPLKFPKKRGPKPGSKRKPRTLLNPPPASPTTSTPEPDTSTVPQDAAT----- 348
P+ T P + P P + ++P PA T P P T P T
Sbjct: 323 KEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSP 382
Query: 349 ------IPSSAMQAPT 358
P++ APT
Sbjct: 383 TTPKEPAPTTTKSAPT 398
Score = 36.6 bits (83), Expect = 0.076
Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 12/93 (12%)
Query: 253 TEKPSIHSSTKTVLEHQPGQRGRKPGKKRGRTPKTLISHPISAPSKTAEPLKFPKKRGPK 312
T P + ++ KT+ + + + K + R + + P K +P K PKK
Sbjct: 846 TLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTP-----KPQKPTKAPKK---- 896
Query: 313 PGSKRKPRTLLNPPPASP-TTSTPEPDTSTVPQ 344
P S +KP+T+ P P TT TP TST+P+
Sbjct: 897 PTSTKKPKTM--PRVRKPKTTPTPRKMTSTMPE 927
Score = 35.8 bits (81), Expect = 0.13
Identities = 34/129 (26%), Positives = 50/129 (38%), Gaps = 17/129 (13%)
Query: 235 PGTKVVIPKNPYPASDVNTEKPSIHSSTKTVLEHQPGQRGRKPGKKRGRTPKTL--ISHP 292
P K + P + ++KP+ + +T P K TP+T +
Sbjct: 663 PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSE 722
Query: 293 ISAPSKTAEPL---KFPKKRGPKPGSKRKPRTLLNPP--PASPTTSTPEPDTSTVPQDAA 347
+S P+ T EP K P + P+ ++ P+ L N P P PTT TP AA
Sbjct: 723 VSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTP----------AA 772
Query: 348 TIPSSAMQA 356
T P A
Sbjct: 773 TKPEMTTTA 781
Score = 35.4 bits (80), Expect = 0.17
Identities = 35/124 (28%), Positives = 48/124 (38%), Gaps = 15/124 (12%)
Query: 235 PGTKVVIPKNPYPASDVNTEKPSIHSSTKTVLEHQPGQRGRKPGKKRGRTPKTLISHPI- 293
P +KV+ P P ++ T+ P++ T E P P + TPK I
Sbjct: 189 PTSKVLA--KPTPKAETTTKGPAL----TTPKEPTP----TTPKEPASTTPKEPTPTTIK 238
Query: 294 SAPSKTAEPLKFPKKRGPKPGSKRKPRTLLNPPPASPTTSTPEPDTSTVPQDAATIPSSA 353
SAP+ EP K P + P T P P +P EP +T + A T SA
Sbjct: 239 SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTP----KEPAPTTTKEPAPTTTKSA 294
Query: 354 MQAP 357
P
Sbjct: 295 PTTP 298
Score = 35.0 bits (79), Expect = 0.22
Identities = 30/121 (24%), Positives = 44/121 (36%), Gaps = 8/121 (6%)
Query: 242 PKNPYPASDVNTEKPSIHSSTKTVLEHQPGQRGRKPGKKRGRTPKTLISHPISAPSKTAE 301
PK P P + + T + ++P + P + SAP+ T E
Sbjct: 345 PKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTK--SAPTTTKE 402
Query: 302 PLKFPKKRGPKPGSKRKPRTLLNPPPAS---PTTSTPEPDTSTVPQD-AATIPSSAMQAP 357
P K P + P T P P + P +TP+ T P++ A T P AP
Sbjct: 403 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE--PAP 460
Query: 358 T 358
T
Sbjct: 461 T 461
Score = 33.5 bits (75), Expect = 0.64
Identities = 31/118 (26%), Positives = 42/118 (35%), Gaps = 8/118 (6%)
Query: 242 PKNPYPASDVNTEKPSIHSSTKTVLEHQPGQRGRKPGKKRGRTPKTLISHPISAPSKTAE 301
PK P P + T + T T E KP TP+ L P+ T
Sbjct: 471 PKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPT---TPEELAPTTPEEPTPTTP 527
Query: 302 PLKFPKKRGPKPGSKRKPRTLLNPPPASPTTSTPEPDTSTVPQDAA-TIPSSAMQAPT 358
+ P PK + P+ P P +TP+ T P++ A T P APT
Sbjct: 528 --EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT--APT 581
Score = 32.7 bits (73), Expect = 1.1
Identities = 30/125 (24%), Positives = 51/125 (40%), Gaps = 8/125 (6%)
Query: 238 KVVIPKNPYPASDVNTEKPSIHSSTKTVLEHQPGQRGRKPGKKRGRTPKTLISHPISAPS 297
K + P+ P + +++ S+ + +T +E + K G+ T S
Sbjct: 122 KPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEK 181
Query: 298 KTAEPL----KFPKKRGPKPGSKRKPRTLLNPPPASPTTSTPEPDTSTVPQDAATIPSSA 353
+A+ L K K PK + K L P PT +TP+ ST P++ P++
Sbjct: 182 TSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKE--PTPTTPKEPASTTPKEPT--PTTI 237
Query: 354 MQAPT 358
APT
Sbjct: 238 KSAPT 242
Score = 32.3 bits (72), Expect = 1.4
Identities = 32/126 (25%), Positives = 46/126 (36%), Gaps = 11/126 (8%)
Query: 242 PKNPYP----ASDVNTEKPSIHSSTKTVLEHQPGQRG-RKPGKKRGRTPKTLISHPISAP 296
P+ P P A+ NT K ++ K P + P + TPK + P
Sbjct: 527 PEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP 586
Query: 297 SKTAEPLKFPKKRGPKPGSKRKPRTLLNPPPASPTTSTP----EPDTSTVPQDAATIPSS 352
+ T PK+ P + T P P +P + P EP +T + A T P
Sbjct: 587 APTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG 646
Query: 353 AMQAPT 358
APT
Sbjct: 647 T--APT 650
Score = 32.0 bits (71), Expect = 1.9
Identities = 32/107 (29%), Positives = 41/107 (38%), Gaps = 15/107 (14%)
Query: 242 PKNPYPASDVNTEKPSIHSSTKTVLEHQPGQRG-RKPGKKRGRTPKTLISHPISAPSKTA 300
PK P P T K ++TK P + P + TPK L + P K A
Sbjct: 447 PKEPAPT----TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTP---TTPEKLA 499
Query: 301 EPLKFPKKRGPKPGSKRKPRTLLNPPPASPTTSTPEPDTSTVPQDAA 347
P+K P + P T P PT +TPE T P+ AA
Sbjct: 500 PTT--PEKPAPTTPEELAPTT-----PEEPTPTTPEEPAPTTPKAAA 539
Score = 30.8 bits (68), Expect = 4.2
Identities = 30/122 (24%), Positives = 45/122 (36%), Gaps = 19/122 (15%)
Query: 242 PKNPYPASDVNTEKPSIHSSTKTVLEHQPGQRGRKPGKKRGRTPKTLISHPISAPSKTAE 301
PK P P + + T T + +P ++P + P +AP K A
Sbjct: 306 PKKPAPTTPKEPAPTTPKEPTPTTPK-EPAPTTKEPAPTTPKEPAP------TAPKKPAP 358
Query: 302 PLKFPKKRGPKPGSKRKPRTLLNPPPASP-----TTSTPEPDTSTVPQDAATIPSSAMQA 356
PK+ P + P T P P +P TT+ P T+ P P++ A
Sbjct: 359 TT--PKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP-----APTTTKSA 411
Query: 357 PT 358
PT
Sbjct: 412 PT 413
Score = 30.4 bits (67), Expect = 5.4
Identities = 35/121 (28%), Positives = 44/121 (36%), Gaps = 17/121 (14%)
Query: 243 KNPYPASDVNTEKPSIHSSTKTVLEHQPGQRGRKPGKKRGRTPKTLISHPISAPSKTAEP 302
K P P + + S T E P P + TPK AP+ EP
Sbjct: 401 KEPAPTTTKSAPTTPKEPSPTTTKEPAP----TTPKEPAPTTPKK------PAPTTPKEP 450
Query: 303 LKF-PKKRGPKPGSKRKPRTLLNPPPASP---TTSTPEPDTSTVPQD-AATIPSSAMQAP 357
PK+ P K P T P P +P +TP+ T T P+ A T P AP
Sbjct: 451 APTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK--PAP 508
Query: 358 T 358
T
Sbjct: 509 T 509
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,972,586
Number of Sequences: 37866
Number of extensions: 1584179
Number of successful extensions: 9745
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 72
Number of HSP's successfully gapped in prelim test: 417
Number of HSP's that attempted gapping in prelim test: 7733
Number of HSP's gapped (non-prelim): 1685
length of query: 660
length of database: 18,247,518
effective HSP length: 109
effective length of query: 551
effective length of database: 14,120,124
effective search space: 7780188324
effective search space used: 7780188324
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.