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Search of human proteins with 71040111
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|71040111 fibromodulin precursor [Homo sapiens]
(376 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|71040111 fibromodulin precursor [Homo sapiens] 780 0.0
gi|4505047 lumican precursor [Homo sapiens] 310 2e-84
gi|41349454 proline arginine-rich end leucine-rich repeat protei... 265 4e-71
gi|4506041 proline arginine-rich end leucine-rich repeat protein... 265 4e-71
gi|5901992 keratocan [Homo sapiens] 255 5e-68
gi|4826876 osteomodulin [Homo sapiens] 225 4e-59
gi|226342933 podocan-like 1 isoform 2 [Homo sapiens] 137 1e-32
gi|226342931 podocan-like 1 isoform 1 [Homo sapiens] 137 1e-32
gi|4557543 extracellular matrix protein 2 precursor [Homo sapiens] 125 8e-29
gi|7019381 fibronectin leucine rich transmembrane protein 2 [Hom... 123 2e-28
gi|38202222 fibronectin leucine rich transmembrane protein 3 pre... 122 4e-28
gi|7019383 fibronectin leucine rich transmembrane protein 3 prec... 122 4e-28
gi|41350214 asporin [Homo sapiens] 122 7e-28
gi|19743846 decorin isoform a preproprotein [Homo sapiens] 120 2e-27
gi|4503271 decorin isoform a preproprotein [Homo sapiens] 120 2e-27
gi|34577057 fibronectin leucine rich transmembrane protein 1 [Ho... 119 3e-27
gi|45505137 podocan [Homo sapiens] 117 1e-26
gi|226342935 podocan-like 1 isoform 3 [Homo sapiens] 117 2e-26
gi|4502403 biglycan preproprotein [Homo sapiens] 113 2e-25
gi|225579152 insulin-like growth factor binding protein, acid la... 93 4e-19
gi|4826772 insulin-like growth factor binding protein, acid labi... 93 4e-19
gi|7662320 leucine-rich repeats and immunoglobulin-like domains ... 91 2e-18
gi|157694513 leucine-rich repeat-containing G protein-coupled re... 90 4e-18
gi|40255157 leucine-rich repeats and immunoglobulin-like domains... 89 5e-18
gi|209862903 leucine-rich repeats and immunoglobulin-like domain... 89 5e-18
gi|109809759 leucine rich repeat transmembrane neuronal 3 [Homo ... 89 8e-18
gi|153251229 chondroadherin precursor [Homo sapiens] 88 1e-17
gi|86990456 leucine rich repeat transmembrane neuronal 1 [Homo s... 87 2e-17
gi|62912470 leucine-rich repeat-containing G protein-coupled rec... 87 2e-17
gi|76880480 hypothetical protein LOC9865 [Homo sapiens] 85 1e-16
>gi|71040111 fibromodulin precursor [Homo sapiens]
Length = 376
Score = 780 bits (2015), Expect = 0.0
Identities = 376/376 (100%), Positives = 376/376 (100%)
Query: 1 MQWTSLLLLAGLFSLSQAQYEDDPHWWFHYLRSQQSTYYDPYDPYPYETYEPYPYGVDEG 60
MQWTSLLLLAGLFSLSQAQYEDDPHWWFHYLRSQQSTYYDPYDPYPYETYEPYPYGVDEG
Sbjct: 1 MQWTSLLLLAGLFSLSQAQYEDDPHWWFHYLRSQQSTYYDPYDPYPYETYEPYPYGVDEG 60
Query: 61 PAYTYGSPSPPDPRDCPQECDCPPNFPTAMYCDNRNLKYLPFVPSRMKYVYFQNNQITSI 120
PAYTYGSPSPPDPRDCPQECDCPPNFPTAMYCDNRNLKYLPFVPSRMKYVYFQNNQITSI
Sbjct: 61 PAYTYGSPSPPDPRDCPQECDCPPNFPTAMYCDNRNLKYLPFVPSRMKYVYFQNNQITSI 120
Query: 121 QEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLPRSLRE 180
QEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLPRSLRE
Sbjct: 121 QEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLPRSLRE 180
Query: 181 LHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVGSSMRGLRSLILLDLSYNHLRKVPD 240
LHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVGSSMRGLRSLILLDLSYNHLRKVPD
Sbjct: 181 LHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVGSSMRGLRSLILLDLSYNHLRKVPD 240
Query: 241 GLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNTFNSSSLLELDL 300
GLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNTFNSSSLLELDL
Sbjct: 241 GLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNTFNSSSLLELDL 300
Query: 301 SYNQLQKIPPVNTNLENLYLQGNRINEFSISSFCTVVDVVNFSKLQVLRLDGNEIKRSAM 360
SYNQLQKIPPVNTNLENLYLQGNRINEFSISSFCTVVDVVNFSKLQVLRLDGNEIKRSAM
Sbjct: 301 SYNQLQKIPPVNTNLENLYLQGNRINEFSISSFCTVVDVVNFSKLQVLRLDGNEIKRSAM 360
Query: 361 PADAPLCLRLASLIEI 376
PADAPLCLRLASLIEI
Sbjct: 361 PADAPLCLRLASLIEI 376
>gi|4505047 lumican precursor [Homo sapiens]
Length = 338
Score = 310 bits (793), Expect = 2e-84
Identities = 148/318 (46%), Positives = 221/318 (69%), Gaps = 8/318 (2%)
Query: 61 PAYTYGSPSPPDPRDCPQECDCPPNFPTAMYCDNRNLKYLPFVPSRMKYVYFQNNQITSI 120
P YG SP +C EC+CP ++P+AMYCD LK +P VP +KY+Y +NNQI I
Sbjct: 26 PLSIYGQSSP----NCAPECNCPESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQIDHI 81
Query: 121 QEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLPRSLRE 180
E F+N T L W+ L N + + K+ +VFSKL+ L++L+++HNNLT GPLP+SL +
Sbjct: 82 DEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLED 141
Query: 181 LHLDHNQISRVPNNALEGLENLTALYLQHNEIQE--VGSSMRGLRSLILLDLSYNHLRKV 238
L L HN+I+++ + EGL NLT ++LQHN ++E V ++ +GL+SL LDLS+N + ++
Sbjct: 142 LQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVSAAFKGLKSLEYLDLSFNQIARL 199
Query: 239 PDGLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNTFNSSSLLEL 298
P GLP +L LY+++N + +PD YF+ L Y+RLSHN L ++G+ N+FN SSL+EL
Sbjct: 200 PSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVEL 259
Query: 299 DLSYNQLQKIPPVNTNLENLYLQGNRINEFSISSFCTVVDVVNFSKLQVLRLDGNEIKRS 358
DLSYN+L+ IP VN NLEN YL+ N++ +F I SFC ++ +++SK++ LRLDGN I +
Sbjct: 260 DLSYNKLKNIPTVNENLENYYLEVNQLEKFDIKSFCKILGPLSYSKIKHLRLDGNRISET 319
Query: 359 AMPADAPLCLRLASLIEI 376
++P D CLR+A+ + +
Sbjct: 320 SLPPDMYECLRVANEVTL 337
>gi|41349454 proline arginine-rich end leucine-rich repeat protein
precursor [Homo sapiens]
Length = 382
Score = 265 bits (678), Expect = 4e-71
Identities = 145/352 (41%), Positives = 207/352 (58%), Gaps = 29/352 (8%)
Query: 41 PYDPYPYETYEPYPYGVDEGPAYTYGSPSPPDPR----DCPQECDCPPNFPTAMYCDNRN 96
P P P E EP D P P PP P DCP+EC CPP+FP+A+YCD+RN
Sbjct: 44 PSFPQPDEPAEP----TDLPP------PLPPGPPSIFPDCPRECYCPPDFPSALYCDSRN 93
Query: 97 LKYLPFVPSRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRH 156
L+ +P +P R+ Y+Y QNN IT + F NATGL WI L N+I K+ ++V KL
Sbjct: 94 LRKVPVIPPRIHYLYLQNNFITELPVESFQNATGLRWINLDNNRIR--KIDQRVLEKLPG 151
Query: 157 LERLYLDHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQE-- 214
L LY++ N L +P LPR+L +L L N ISR+P LENL L LQHN + +
Sbjct: 152 LVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGV 211
Query: 215 -VGSSMRGLRSLILLDLSYNHLRKVPDGLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYV 273
+ GL++L+ L+L++N LRK+P +P+A+ QLY++ N + T+P+ YF+ P L ++
Sbjct: 212 FKPDTFHGLKNLMQLNLAHNILRKMPPRVPTAIHQLYLDSNKIETIPNGYFKSFPNLAFI 271
Query: 274 RLSHNSLTNNGLASNTFNSSSLLELDLSYNQLQKIPPVNTNLENLYLQGNRINEFSISSF 333
RL++N LT+ GL N+FN S+LL L LS+N++ +P +N LE+LYL N I + + +
Sbjct: 272 RLNYNKLTDRGLPKNSFNISNLLVLHLSHNRISSVPAINNRLEHLYLNNNSIEKINGTQI 331
Query: 334 CT---------VVDVVNFSKLQVLRLDGNEIKRSAMPADAPLCLRLASLIEI 376
C D+ N L+ LRLDGN +K +P D +C RL + I
Sbjct: 332 CPNDLVAFHDFSSDLENVPHLRYLRLDGNYLK-PPIPLDLMMCFRLLQSVVI 382
>gi|4506041 proline arginine-rich end leucine-rich repeat protein
precursor [Homo sapiens]
Length = 382
Score = 265 bits (678), Expect = 4e-71
Identities = 145/352 (41%), Positives = 207/352 (58%), Gaps = 29/352 (8%)
Query: 41 PYDPYPYETYEPYPYGVDEGPAYTYGSPSPPDPR----DCPQECDCPPNFPTAMYCDNRN 96
P P P E EP D P P PP P DCP+EC CPP+FP+A+YCD+RN
Sbjct: 44 PSFPQPDEPAEP----TDLPP------PLPPGPPSIFPDCPRECYCPPDFPSALYCDSRN 93
Query: 97 LKYLPFVPSRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRH 156
L+ +P +P R+ Y+Y QNN IT + F NATGL WI L N+I K+ ++V KL
Sbjct: 94 LRKVPVIPPRIHYLYLQNNFITELPVESFQNATGLRWINLDNNRIR--KIDQRVLEKLPG 151
Query: 157 LERLYLDHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQE-- 214
L LY++ N L +P LPR+L +L L N ISR+P LENL L LQHN + +
Sbjct: 152 LVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGV 211
Query: 215 -VGSSMRGLRSLILLDLSYNHLRKVPDGLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYV 273
+ GL++L+ L+L++N LRK+P +P+A+ QLY++ N + T+P+ YF+ P L ++
Sbjct: 212 FKPDTFHGLKNLMQLNLAHNILRKMPPRVPTAIHQLYLDSNKIETIPNGYFKSFPNLAFI 271
Query: 274 RLSHNSLTNNGLASNTFNSSSLLELDLSYNQLQKIPPVNTNLENLYLQGNRINEFSISSF 333
RL++N LT+ GL N+FN S+LL L LS+N++ +P +N LE+LYL N I + + +
Sbjct: 272 RLNYNKLTDRGLPKNSFNISNLLVLHLSHNRISSVPAINNRLEHLYLNNNSIEKINGTQI 331
Query: 334 CT---------VVDVVNFSKLQVLRLDGNEIKRSAMPADAPLCLRLASLIEI 376
C D+ N L+ LRLDGN +K +P D +C RL + I
Sbjct: 332 CPNDLVAFHDFSSDLENVPHLRYLRLDGNYLK-PPIPLDLMMCFRLLQSVVI 382
>gi|5901992 keratocan [Homo sapiens]
Length = 352
Score = 255 bits (651), Expect = 5e-68
Identities = 131/313 (41%), Positives = 204/313 (65%), Gaps = 12/313 (3%)
Query: 75 DCPQECDCPPNFPTAMYCDNRNLKYLPFVPSRMKYVYFQNNQITSIQEGVFDNATGLLWI 134
+CP EC CPP+FPTA+YC+NR LK +P +PSR+ Y+Y QNN I +I E F+NAT L WI
Sbjct: 41 ECPMECFCPPSFPTALYCENRGLKEIPAIPSRIWYLYLQNNLIETIPEKPFENATQLRWI 100
Query: 135 ALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLPRSLRELHLDHNQISRVPNN 194
L+ N+IT+ + + S+L+ L L+L+ N L +P PLPRSL +L L N++SR+P
Sbjct: 101 NLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQG 160
Query: 195 ALEGLENLTALYLQHNEIQEVG---SSMRGLRSLILLDLSYNHLRKVPDGLPSALEQLYM 251
LENLT L LQ+N++ + + +GL++L+ L+++ N LR +P LP+ QL++
Sbjct: 161 TFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFL 220
Query: 252 EHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNTFNSSSLLELDLSYNQLQKIPPV 311
++N++ +P++YF PK+ ++RL+HN L++ GL S F+ SS+L+L LS+NQL K+P +
Sbjct: 221 DNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGFDVSSILDLQLSHNQLTKVPRI 280
Query: 312 NTNLENLYLQGNRINEFSISSFCTVVDVV-----NFS---KLQVLRLDGNEIKRSAMPAD 363
+ +L++L+L N+I ++S C ++ +FS L+ LRLDGNEIK +P
Sbjct: 281 SAHLQHLHLDHNKIKSVNVSVICPSPSMLPAERDSFSYGPHLRYLRLDGNEIK-PPIPMA 339
Query: 364 APLCLRLASLIEI 376
C RL + I
Sbjct: 340 LMTCFRLLQAVII 352
>gi|4826876 osteomodulin [Homo sapiens]
Length = 421
Score = 225 bits (574), Expect = 4e-59
Identities = 127/331 (38%), Positives = 195/331 (58%), Gaps = 16/331 (4%)
Query: 34 QQSTYY--DPYDPYP---YETYEPYPYGVDEGPAYTYGSPSPPDPRDCPQECDCPPNFPT 88
Q TY + YD P Y+T P+ VD YG P C EC CP NFP+
Sbjct: 21 QYETYQWDEDYDQEPDDDYQTGFPFRQNVD------YGVPFHQYTLGCVSECFCPTNFPS 74
Query: 89 AMYCDNRNLKYLPFVPSRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGR 148
+MYCDNR LK +P +P ++ +Y Q N+I ++ F NAT L I L N+I S K+
Sbjct: 75 SMYCDNRKLKTIPNIPMHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDY 134
Query: 149 KVFSKLRHLERLYLDHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQ 208
VF+KL +L +L+L+HNNL P PLP+SL L L +N+IS++ NA++GL NLT L L
Sbjct: 135 GVFAKLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLC 194
Query: 209 HNEIQE---VGSSMRGLRSLILLDLSYNHLRKVPDGLPSALEQLYMEHNNVYTVPDSYFR 265
+N + + + L+ L+L N L +P GLPS+L L +E+N++ ++P+ YF
Sbjct: 195 YNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSLENNSISSIPEKYFD 254
Query: 266 GAPKLLYVRLSHNSLTNNGLASNTFNSSSLLELDLSYNQLQKIPPVNTNLENLYLQGNRI 325
PKL +R+SHN L + + N FN +++EL + +N+L++ + NLE+LYLQ N I
Sbjct: 255 KLPKLHTLRMSHNKLQD--IPYNIFNLPNIVELSVGHNKLKQAFYIPRNLEHLYLQNNEI 312
Query: 326 NEFSISSFCTVVDVVNFSKLQVLRLDGNEIK 356
+ +++ C +D +++ L +R+D N++K
Sbjct: 313 EKMNLTVMCPSIDPLHYHHLTYIRVDQNKLK 343
>gi|226342933 podocan-like 1 isoform 2 [Homo sapiens]
Length = 510
Score = 137 bits (346), Expect = 1e-32
Identities = 100/320 (31%), Positives = 156/320 (48%), Gaps = 14/320 (4%)
Query: 56 GVDEGPAYTYGSPSPPDPRDCPQECDCPPNFPTAMYCDNRNLKYLPFVPSRM-KYVYFQN 114
G+++ G P PR CP C CP + CD +L+ P +R +++ QN
Sbjct: 24 GLEDAAFPHLGESLQPLPRACPLRCSCPR--VDTVDCDGLDLRVFPDNITRAAQHLSLQN 81
Query: 115 NQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPL 174
NQ+ + +GL + LH N I+S+ + + F L L+ L + HN L+ P L
Sbjct: 82 NQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAHNKLSVAPQFL 141
Query: 175 PRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVG---SSMRGLRSLILLDLS 231
PRSLR L NQ+ + L ++YL +N++ G + RG ++ L LS
Sbjct: 142 PRSLRVADLAANQVMEIFPLTFGEKPALRSVYLHNNQLSNAGLPPDAFRGSEAIATLSLS 201
Query: 232 YNHLRKVPDGLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNTFN 291
N L +P LP +LE+L++++N + VP +L + L HN LT++GL + TF+
Sbjct: 202 NNQLSYLPPSLPPSLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFS 261
Query: 292 SSSLLE-LDLSYNQLQKIPP-VNTNLENLYLQGNRINEFSISSFCTVVDVVNFSKLQVLR 349
LE LDLS+NQL +P + L L+L NRI + + + L+ L
Sbjct: 262 KLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAAR------LHGARGLRYLL 315
Query: 350 LDGNEIKRSAMPADAPLCLR 369
L N++ S +PA A LR
Sbjct: 316 LQHNQLGSSGLPAGALRPLR 335
Score = 126 bits (317), Expect = 3e-29
Identities = 86/238 (36%), Positives = 120/238 (50%), Gaps = 6/238 (2%)
Query: 94 NRNLKYLP-FVPSRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFS 152
N L YLP +P ++ ++ QNN I+ + G T L + L NQ+T + FS
Sbjct: 202 NNQLSYLPPSLPPSLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFS 261
Query: 153 KLRHLERLYLDHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEI 212
KL LE L L HN LT +P LPR+L LHL N+I +V L G L L LQHN++
Sbjct: 262 KLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQL 321
Query: 213 QEVG---SSMRGLRSLILLDLSYNHLRKVPDGLPSALEQLYMEHNNVYTVPDSYFRGAPK 269
G ++R LR L L L N L +VP LP L L + HN+V + P
Sbjct: 322 GSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPG 381
Query: 270 LLYVRLSHNSLTNNGLASNTFNS-SSLLELDLSYNQLQKIP-PVNTNLENLYLQGNRI 325
L + L++N L + + F +L LDL+ NQL ++P + T L L LQ N++
Sbjct: 382 LTELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQL 439
Score = 115 bits (288), Expect = 6e-26
Identities = 78/229 (34%), Positives = 111/229 (48%), Gaps = 5/229 (2%)
Query: 102 FVPSRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLY 161
F+P ++ NQ+ I F L + LH NQ+++ + F + L
Sbjct: 140 FLPRSLRVADLAANQVMEIFPLTFGEKPALRSVYLHNNQLSNAGLPPDAFRGSEAIATLS 199
Query: 162 LDHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVG---SS 218
L +N L+ +P LP SL LHL +N IS+VP AL L LYLQHN++ + G ++
Sbjct: 200 LSNNQLSYLPPSLPPSLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATT 259
Query: 219 MRGLRSLILLDLSYNHLRKVPDGLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHN 278
L SL LDLS+N L VP GLP L L++ N + V + GA L Y+ L HN
Sbjct: 260 FSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHN 319
Query: 279 SLTNNGLASNTFNS-SSLLELDLSYNQLQKIPP-VNTNLENLYLQGNRI 325
L ++GL + L L L N L ++PP + L L L N +
Sbjct: 320 QLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHV 368
Score = 89.4 bits (220), Expect = 5e-18
Identities = 58/199 (29%), Positives = 94/199 (47%), Gaps = 3/199 (1%)
Query: 103 VPSRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYL 162
+P + ++ N+I ++ A GL ++ L NQ+ S + LR L L+L
Sbjct: 283 LPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHL 342
Query: 163 DHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVG---SSM 219
N L R+P LPR LR L L HN ++ + L LT L L +N + +
Sbjct: 343 YGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAF 402
Query: 220 RGLRSLILLDLSYNHLRKVPDGLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNS 279
R LR+L LDL+ N L ++P GLP+ L L ++ N + + G +L + L+HN
Sbjct: 403 RRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNR 462
Query: 280 LTNNGLASNTFNSSSLLEL 298
L + T++ L++
Sbjct: 463 LRVGDIGPGTWHELQALQV 481
Score = 63.9 bits (154), Expect = 2e-10
Identities = 37/113 (32%), Positives = 57/113 (50%)
Query: 101 PFVPSRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERL 160
P +P R++ + +N + ++ GL + L N++ S +V + F +LR L L
Sbjct: 352 PALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAFRRLRALRSL 411
Query: 161 YLDHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQ 213
L N LTR+P LP LR L L NQ+ + L GL+ L L L HN ++
Sbjct: 412 DLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRLR 464
>gi|226342931 podocan-like 1 isoform 1 [Homo sapiens]
Length = 512
Score = 137 bits (346), Expect = 1e-32
Identities = 100/320 (31%), Positives = 156/320 (48%), Gaps = 14/320 (4%)
Query: 56 GVDEGPAYTYGSPSPPDPRDCPQECDCPPNFPTAMYCDNRNLKYLPFVPSRM-KYVYFQN 114
G+++ G P PR CP C CP + CD +L+ P +R +++ QN
Sbjct: 26 GLEDAAFPHLGESLQPLPRACPLRCSCPR--VDTVDCDGLDLRVFPDNITRAAQHLSLQN 83
Query: 115 NQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPL 174
NQ+ + +GL + LH N I+S+ + + F L L+ L + HN L+ P L
Sbjct: 84 NQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAHNKLSVAPQFL 143
Query: 175 PRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVG---SSMRGLRSLILLDLS 231
PRSLR L NQ+ + L ++YL +N++ G + RG ++ L LS
Sbjct: 144 PRSLRVADLAANQVMEIFPLTFGEKPALRSVYLHNNQLSNAGLPPDAFRGSEAIATLSLS 203
Query: 232 YNHLRKVPDGLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNTFN 291
N L +P LP +LE+L++++N + VP +L + L HN LT++GL + TF+
Sbjct: 204 NNQLSYLPPSLPPSLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFS 263
Query: 292 SSSLLE-LDLSYNQLQKIPP-VNTNLENLYLQGNRINEFSISSFCTVVDVVNFSKLQVLR 349
LE LDLS+NQL +P + L L+L NRI + + + L+ L
Sbjct: 264 KLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAAR------LHGARGLRYLL 317
Query: 350 LDGNEIKRSAMPADAPLCLR 369
L N++ S +PA A LR
Sbjct: 318 LQHNQLGSSGLPAGALRPLR 337
Score = 126 bits (317), Expect = 3e-29
Identities = 86/238 (36%), Positives = 120/238 (50%), Gaps = 6/238 (2%)
Query: 94 NRNLKYLP-FVPSRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFS 152
N L YLP +P ++ ++ QNN I+ + G T L + L NQ+T + FS
Sbjct: 204 NNQLSYLPPSLPPSLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFS 263
Query: 153 KLRHLERLYLDHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEI 212
KL LE L L HN LT +P LPR+L LHL N+I +V L G L L LQHN++
Sbjct: 264 KLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQL 323
Query: 213 QEVG---SSMRGLRSLILLDLSYNHLRKVPDGLPSALEQLYMEHNNVYTVPDSYFRGAPK 269
G ++R LR L L L N L +VP LP L L + HN+V + P
Sbjct: 324 GSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPG 383
Query: 270 LLYVRLSHNSLTNNGLASNTFNS-SSLLELDLSYNQLQKIP-PVNTNLENLYLQGNRI 325
L + L++N L + + F +L LDL+ NQL ++P + T L L LQ N++
Sbjct: 384 LTELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQL 441
Score = 115 bits (288), Expect = 6e-26
Identities = 78/229 (34%), Positives = 111/229 (48%), Gaps = 5/229 (2%)
Query: 102 FVPSRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLY 161
F+P ++ NQ+ I F L + LH NQ+++ + F + L
Sbjct: 142 FLPRSLRVADLAANQVMEIFPLTFGEKPALRSVYLHNNQLSNAGLPPDAFRGSEAIATLS 201
Query: 162 LDHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVG---SS 218
L +N L+ +P LP SL LHL +N IS+VP AL L LYLQHN++ + G ++
Sbjct: 202 LSNNQLSYLPPSLPPSLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATT 261
Query: 219 MRGLRSLILLDLSYNHLRKVPDGLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHN 278
L SL LDLS+N L VP GLP L L++ N + V + GA L Y+ L HN
Sbjct: 262 FSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHN 321
Query: 279 SLTNNGLASNTFNS-SSLLELDLSYNQLQKIPP-VNTNLENLYLQGNRI 325
L ++GL + L L L N L ++PP + L L L N +
Sbjct: 322 QLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHV 370
Score = 89.4 bits (220), Expect = 5e-18
Identities = 58/199 (29%), Positives = 94/199 (47%), Gaps = 3/199 (1%)
Query: 103 VPSRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYL 162
+P + ++ N+I ++ A GL ++ L NQ+ S + LR L L+L
Sbjct: 285 LPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHL 344
Query: 163 DHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVG---SSM 219
N L R+P LPR LR L L HN ++ + L LT L L +N + +
Sbjct: 345 YGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAF 404
Query: 220 RGLRSLILLDLSYNHLRKVPDGLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNS 279
R LR+L LDL+ N L ++P GLP+ L L ++ N + + G +L + L+HN
Sbjct: 405 RRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNR 464
Query: 280 LTNNGLASNTFNSSSLLEL 298
L + T++ L++
Sbjct: 465 LRVGDIGPGTWHELQALQV 483
Score = 63.9 bits (154), Expect = 2e-10
Identities = 37/113 (32%), Positives = 57/113 (50%)
Query: 101 PFVPSRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERL 160
P +P R++ + +N + ++ GL + L N++ S +V + F +LR L L
Sbjct: 354 PALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAFRRLRALRSL 413
Query: 161 YLDHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQ 213
L N LTR+P LP LR L L NQ+ + L GL+ L L L HN ++
Sbjct: 414 DLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRLR 466
>gi|4557543 extracellular matrix protein 2 precursor [Homo sapiens]
Length = 699
Score = 125 bits (313), Expect = 8e-29
Identities = 84/266 (31%), Positives = 134/266 (50%), Gaps = 8/266 (3%)
Query: 67 SPSPPDPRDCPQ-ECDCPPNFPTAMYCDNRNLKYLP-FVPSRMKYVYFQNNQITSIQEGV 124
SP P PR + C ++ T + C N L +P ++ + N I SI +
Sbjct: 304 SPLPAPPRGTLRLPSGCSLSYRT-ISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEA 362
Query: 125 FDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLPRSLRELHLD 184
F+ L + L N ITS +G K F L+ L RL +D NNL ++P LP +L EL ++
Sbjct: 363 FNGLPNLERLDLSKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELKVN 422
Query: 185 HNQISRVPNNALEGLENLTALYLQHNEIQEVG---SSMRGLRSLILLDLSYNHLRKVPDG 241
N + + +L L L L L+ N + E + + L+SL L L N R +P G
Sbjct: 423 ENNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQG 482
Query: 242 LPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNTF-NSSSLLELDL 300
LP ++E+LY+E+N + + + F K+ + L +N + N +A + N +L +DL
Sbjct: 483 LPGSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDL 542
Query: 301 SYNQLQKIPP-VNTNLENLYLQGNRI 325
SYN+L +P + +L +L L GN+I
Sbjct: 543 SYNKLYHVPSYLPKSLLHLVLLGNQI 568
Score = 75.9 bits (185), Expect = 6e-14
Identities = 60/205 (29%), Positives = 101/205 (49%), Gaps = 14/205 (6%)
Query: 167 LTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVG---SSMRGLR 223
LT++P + L L N I+ +P+ A GL NL L L N I G + + L+
Sbjct: 334 LTQIPPLTAPQITSLELTGNSIASIPDEAFNGLPNLERLDLSKNNITSSGIGPKAFKLLK 393
Query: 224 SLILLDLSYNHLRKVPDGLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNN 283
L+ L++ N+L ++P LPS LE+L + NN+ + + +L+ + L N+L+
Sbjct: 394 KLMRLNMDGNNLIQIPSQLPSTLEELKVNENNLQAIDEESLSDLNQLVTLELEGNNLSEA 453
Query: 284 GLASNTFNS-SSLLELDLSYNQLQKIPP-VNTNLENLYLQGNRINEFSISSFCTVVDVVN 341
+ F SL L L N+ + IP + ++E LYL+ N+I E T + +
Sbjct: 454 NVNPLAFKPLKSLAYLRLGKNKFRIIPQGLPGSIEELYLENNQIEEI------TEICFNH 507
Query: 342 FSKLQVLRLDGNEIKRSAMPADAPL 366
K+ V+ L N+I+ + + APL
Sbjct: 508 TRKINVIVLRYNKIEENRI---APL 529
Score = 73.2 bits (178), Expect = 4e-13
Identities = 56/188 (29%), Positives = 88/188 (46%), Gaps = 7/188 (3%)
Query: 103 VPSRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYL 162
+P ++ +Y +NNQI I E F++ + I L N+I +++ + +LE + L
Sbjct: 483 LPGSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDL 542
Query: 163 DHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLE-NLTALYLQHNEIQEVG----S 217
+N L +P LP+SL L L NQI R+P +E L LYL N++ + G S
Sbjct: 543 SYNKLYHVPSYLPKSLLHLVLLGNQIERIPGYVFGHMEPGLEYLYLSFNKLADDGMDRVS 602
Query: 218 SMRGLRSLILLDLSYNHLRKVPDGLP--SALEQLYMEHNNVYTVPDSYFRGAPKLLYVRL 275
SL L L +N L+ +P G+ AL L + +N + + A + L
Sbjct: 603 FYGAYHSLRELFLDHNDLKSIPPGIQEMKALHFLRLNNNKIRNILPEEICNAEEDDDSNL 662
Query: 276 SHNSLTNN 283
H L NN
Sbjct: 663 EHLHLENN 670
>gi|7019381 fibronectin leucine rich transmembrane protein 2 [Homo
sapiens]
Length = 660
Score = 123 bits (309), Expect = 2e-28
Identities = 95/288 (32%), Positives = 133/288 (46%), Gaps = 41/288 (14%)
Query: 76 CPQECDCPPNFPTAMYCDNRNLKYLPF-VPSRMKYVYFQNNQITSIQEGVFDNATGLLWI 134
CP C C NF +YC+ R+L +P +P + +Y NNQI N G
Sbjct: 36 CPSVCRCDRNF---VYCNERSLTSVPLGIPEGVTVLYLHNNQI---------NNAGFP-A 82
Query: 135 ALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLPRSLRELHLDHNQISRVPNN 194
LH Q + +YL N L P LP+++R LHL N I +
Sbjct: 83 ELHNVQ---------------SVHTVYLYGNQLDEFPMNLPKNVRVLHLQENNIQTISRA 127
Query: 195 ALEGLENLTALYLQHNEIQEVG---SSMRGLRSLILLDLSYNHLRKVPDGLPSALEQLYM 251
AL L L L+L N I VG + R SL LL LS NHL VP GLP L++L +
Sbjct: 128 ALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPVDLQELRV 187
Query: 252 EHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNTFNS-SSLLELDLSYNQLQKIPP 310
+ N + + D F+ L + + N LTN G+A TF+ + L E + N L PP
Sbjct: 188 DENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPP 247
Query: 311 --VNTNLENLYLQGNRINEFSISSFCTVVDVVNFSKLQVLRLDGNEIK 356
T+L LYLQ N+IN +++F N KL+ L + N+++
Sbjct: 248 DLPGTHLIRLYLQDNQINHIPLTAFS------NLRKLERLDISNNQLR 289
Score = 30.0 bits (66), Expect = 3.5
Identities = 15/65 (23%), Positives = 30/65 (46%), Gaps = 8/65 (12%)
Query: 83 PPNFPTA----MYCDNRNLKYLPFVP----SRMKYVYFQNNQITSIQEGVFDNATGLLWI 134
PP+ P +Y + + ++P +++ + NNQ+ + +GVFDN + L +
Sbjct: 246 PPDLPGTHLIRLYLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFDNLSNLKQL 305
Query: 135 ALHGN 139
N
Sbjct: 306 TARNN 310
>gi|38202222 fibronectin leucine rich transmembrane protein 3
precursor [Homo sapiens]
Length = 649
Score = 122 bits (307), Expect = 4e-28
Identities = 98/296 (33%), Positives = 135/296 (45%), Gaps = 45/296 (15%)
Query: 74 RDCPQECDCPPNFPTAMYCDNRNLKYLPF-VPSRMKYVYFQNNQITSIQEGVFDNATGLL 132
+ CP C C F +YC++R L +P +P +Y QNNQI N G
Sbjct: 29 KSCPSVCRCDAGF---IYCNDRFLTSIPTGIPEDATTLYLQNNQI---------NNAG-- 74
Query: 133 WIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLPRSLRELHLDHNQISRVP 192
I SD L +ER+YL HN+L P LP+ ++ELHL N I +
Sbjct: 75 --------IPSD------LKNLLKVERIYLYHNSLDEFPTNLPKYVKELHLQENNIRTIT 120
Query: 193 NNALEGLENLTALYLQHNEIQEVG---SSMRGLRSLILLDLSYNHLRKVPDGLPSALEQL 249
++L + L L+L N + V + R L LL LS NHL +P GLP +E+L
Sbjct: 121 YDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEEL 180
Query: 250 YMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNT-FNSSSLLELDLSYNQLQKI 308
++ N + T+ +G L + L N L N+GL FN +L EL L N L
Sbjct: 181 RLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSL-TA 239
Query: 309 PPVN---TNLENLYLQGNRINEFSISSFCTVVDVVNFSKLQVLRLDGNEIKRSAMP 361
PVN TNL LYLQ N IN ++F + Q+ RLD + S +P
Sbjct: 240 APVNLPGTNLRKLYLQDNHINRVPPNAFSYL--------RQLYRLDMSNNNLSNLP 287
>gi|7019383 fibronectin leucine rich transmembrane protein 3
precursor [Homo sapiens]
Length = 649
Score = 122 bits (307), Expect = 4e-28
Identities = 98/296 (33%), Positives = 135/296 (45%), Gaps = 45/296 (15%)
Query: 74 RDCPQECDCPPNFPTAMYCDNRNLKYLPF-VPSRMKYVYFQNNQITSIQEGVFDNATGLL 132
+ CP C C F +YC++R L +P +P +Y QNNQI N G
Sbjct: 29 KSCPSVCRCDAGF---IYCNDRFLTSIPTGIPEDATTLYLQNNQI---------NNAG-- 74
Query: 133 WIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLPRSLRELHLDHNQISRVP 192
I SD L +ER+YL HN+L P LP+ ++ELHL N I +
Sbjct: 75 --------IPSD------LKNLLKVERIYLYHNSLDEFPTNLPKYVKELHLQENNIRTIT 120
Query: 193 NNALEGLENLTALYLQHNEIQEVG---SSMRGLRSLILLDLSYNHLRKVPDGLPSALEQL 249
++L + L L+L N + V + R L LL LS NHL +P GLP +E+L
Sbjct: 121 YDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEEL 180
Query: 250 YMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNT-FNSSSLLELDLSYNQLQKI 308
++ N + T+ +G L + L N L N+GL FN +L EL L N L
Sbjct: 181 RLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSL-TA 239
Query: 309 PPVN---TNLENLYLQGNRINEFSISSFCTVVDVVNFSKLQVLRLDGNEIKRSAMP 361
PVN TNL LYLQ N IN ++F + Q+ RLD + S +P
Sbjct: 240 APVNLPGTNLRKLYLQDNHINRVPPNAFSYL--------RQLYRLDMSNNNLSNLP 287
>gi|41350214 asporin [Homo sapiens]
Length = 380
Score = 122 bits (305), Expect = 7e-28
Identities = 83/290 (28%), Positives = 140/290 (48%), Gaps = 18/290 (6%)
Query: 76 CPQECDCPPNFPTAMYCDNRNLKYLPF-VPSRMKYVYFQNNQITSIQEGVFDNATGLLWI 134
CP C C + ++C + L +P +P + + QNN+I I+E F T L +
Sbjct: 75 CPFGCQC---YSRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGL 131
Query: 135 ALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLPRSLRELHLDHNQISRVPNN 194
L+ N++T K+ K F + L RLYL HN L+ +P LP+SL EL + N++ ++ +
Sbjct: 132 ILNNNKLT--KIHPKAFLTTKKLRRLYLSHNQLSEIPLNLPKSLAELRIHENKVKKIQKD 189
Query: 195 ALEGLENLTALYLQHNEIQEVGSSMRGLRSLIL--LDLSYNHLRKVPDGLPSALEQLYME 252
+G+ L L + N + G + + + ++ L VP GLP L +L+++
Sbjct: 190 TFKGMNALHVLEMSANPLDNNGIEPGAFEGVTVFHIRIAEAKLTSVPKGLPPTLLELHLD 249
Query: 253 HNNVYTVPDSYFRGAPKLLYVRLSHNSLT---NNGLASNTFNSSSLLELDLSYNQLQKIP 309
+N + TV F+ +L + L +N +T N LA N + E+ L N+L+KIP
Sbjct: 250 YNKISTVELEDFKRYKELQRLGLGNNKITDIENGSLA----NIPRVREIHLENNKLKKIP 305
Query: 310 ---PVNTNLENLYLQGNRINEFSISSFCTVVDVVNFSKLQVLRLDGNEIK 356
P L+ ++L N I ++ FC V + S + L N +K
Sbjct: 306 SGLPELKYLQIIFLHSNSIARVGVNDFCPTVPKMKKSLYSAISLFNNPVK 355
>gi|19743846 decorin isoform a preproprotein [Homo sapiens]
Length = 359
Score = 120 bits (301), Expect = 2e-27
Identities = 85/284 (29%), Positives = 140/284 (49%), Gaps = 25/284 (8%)
Query: 68 PSPPDPRD--------CPQECDCPPNFPTAMYCDNRNLKYLPF-VPSRMKYVYFQNNQIT 118
P PD RD CP C C + C + L +P +P + QNN+IT
Sbjct: 38 PEVPDDRDFEPSLGPVCPFRCQCHLR---VVQCSDLGLDKVPKDLPPDTTLLDLQNNKIT 94
Query: 119 SIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLPRSL 178
I++G F N L + L N+I+ KV F+ L LERLYL N L +P +P++L
Sbjct: 95 EIKDGDFKNLKNLHALILVNNKIS--KVSPGAFTPLVKLERLYLSKNQLKELPEKMPKTL 152
Query: 179 RELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVG---SSMRGLRSLILLDLSYNHL 235
+EL N+I++V GL + + L N ++ G + +G++ L + ++ ++
Sbjct: 153 QELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNI 212
Query: 236 RKVPDGLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLT--NNGLASNTFNSS 293
+P GLP +L +L+++ N + V + +G L + LS NS++ +NG +NT
Sbjct: 213 TSIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANT---P 269
Query: 294 SLLELDLSYNQLQKIP---PVNTNLENLYLQGNRINEFSISSFC 334
L EL L N+L ++P + ++ +YL N I+ S FC
Sbjct: 270 HLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFC 313
>gi|4503271 decorin isoform a preproprotein [Homo sapiens]
Length = 359
Score = 120 bits (301), Expect = 2e-27
Identities = 85/284 (29%), Positives = 140/284 (49%), Gaps = 25/284 (8%)
Query: 68 PSPPDPRD--------CPQECDCPPNFPTAMYCDNRNLKYLPF-VPSRMKYVYFQNNQIT 118
P PD RD CP C C + C + L +P +P + QNN+IT
Sbjct: 38 PEVPDDRDFEPSLGPVCPFRCQCHLR---VVQCSDLGLDKVPKDLPPDTTLLDLQNNKIT 94
Query: 119 SIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLPRSL 178
I++G F N L + L N+I+ KV F+ L LERLYL N L +P +P++L
Sbjct: 95 EIKDGDFKNLKNLHALILVNNKIS--KVSPGAFTPLVKLERLYLSKNQLKELPEKMPKTL 152
Query: 179 RELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVG---SSMRGLRSLILLDLSYNHL 235
+EL N+I++V GL + + L N ++ G + +G++ L + ++ ++
Sbjct: 153 QELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNI 212
Query: 236 RKVPDGLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLT--NNGLASNTFNSS 293
+P GLP +L +L+++ N + V + +G L + LS NS++ +NG +NT
Sbjct: 213 TSIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANT---P 269
Query: 294 SLLELDLSYNQLQKIP---PVNTNLENLYLQGNRINEFSISSFC 334
L EL L N+L ++P + ++ +YL N I+ S FC
Sbjct: 270 HLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFC 313
>gi|34577057 fibronectin leucine rich transmembrane protein 1 [Homo
sapiens]
Length = 674
Score = 119 bits (299), Expect = 3e-27
Identities = 94/292 (32%), Positives = 135/292 (46%), Gaps = 43/292 (14%)
Query: 72 DPRDCPQECDCPPNFPTAMYCDNRNLKYLPF-VPSRMKYVYFQNNQITSIQEGVFDNATG 130
D CP C C F +YC++R L +P +P +Y QNNQI N G
Sbjct: 50 DSTTCPSVCRCDNGF---IYCNDRGLTSIPADIPDDATTLYLQNNQI---------NNAG 97
Query: 131 LLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLPRSLRELHLDHNQISR 190
+ Q KV +V +YL N+L P LPRSLRELHL N +
Sbjct: 98 I-------PQDLKTKVNVQV---------IYLYENDLDEFPINLPRSLRELHLQDNNVRT 141
Query: 191 VPNNALEGLENLTALYLQHNEIQEVG---SSMRGLRSLILLDLSYNHLRKVPDGLPSALE 247
+ ++L + L L+L N + V + + L LL LS NHL +P GLP LE
Sbjct: 142 IARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLE 201
Query: 248 QLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNTFNS-SSLLELDLSYNQLQ 306
+L ++ N + T+P F+G L + L N L N +A +TF+ +L EL L N L
Sbjct: 202 ELRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSL- 260
Query: 307 KIPPVN---TNLENLYLQGNRINEFSISSFCTVVDVVNFSKLQVLRLDGNEI 355
PP+N +L+ LYLQ N I+ ++ + +L+ L L N +
Sbjct: 261 AAPPLNLPSAHLQKLYLQDNAISHIPYNT------LAKMRELERLDLSNNNL 306
Score = 84.7 bits (208), Expect = 1e-16
Identities = 62/214 (28%), Positives = 107/214 (50%), Gaps = 7/214 (3%)
Query: 90 MYCDNRNLKYLPF-VPSRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGR 148
+Y +L P +P ++ ++ Q+N + +I L + L N +++ +
Sbjct: 111 IYLYENDLDEFPINLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEE 170
Query: 149 KVFSKLRHLERLYLDHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQ 208
F+ + L+ L+L N+L+ +P LP +L EL LD N+IS +P +A +GL +L L L
Sbjct: 171 DAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELRLDDNRISTIPLHAFKGLNSLRRLVLD 230
Query: 209 HNEIQE---VGSSMRGLRSLILLDLSYNHLRKVPDGLPSA-LEQLYMEHNNVYTVPDSYF 264
N + + L++L L L N L P LPSA L++LY++ N + +P +
Sbjct: 231 GNLLANQRIADDTFSRLQNLTELSLVRNSLAAPPLNLPSAHLQKLYLQDNAISHIPYNTL 290
Query: 265 RGAPKLLYVRLSHNSLTN--NGLASNTFNSSSLL 296
+L + LS+N+LT GL + N + LL
Sbjct: 291 AKMRELERLDLSNNNLTTLPRGLFDDLGNLAQLL 324
>gi|45505137 podocan [Homo sapiens]
Length = 661
Score = 117 bits (294), Expect = 1e-26
Identities = 87/286 (30%), Positives = 145/286 (50%), Gaps = 12/286 (4%)
Query: 97 LKYLP-FVPSRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLR 155
L+++P +P + ++ +NN++ I G F + L + L N +T + + + F KL
Sbjct: 277 LRHVPKHLPPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLS 336
Query: 156 HLERLYLDHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEV 215
LE L L NNL+R+P LPRSL LHL+ N I V N L + +L L L N+++E
Sbjct: 337 SLEYLDLSSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQ 396
Query: 216 G---SSMRGLRSLILLDLSYNHLRKVPDGLPSALEQLYMEHNNVYTVPDSYFRGAPKLLY 272
G + +GL+ L + L N L +VP GLP + L + HN + + F L
Sbjct: 397 GIHPLAFQGLKRLHTVHLYNNALERVPSGLPRRVRTLMILHNQITGIGREDFATTYFLEE 456
Query: 273 VRLSHNSLTNNGLASNTFNSSSLL-ELDLSYNQLQKIPP-VNTNLENLYLQGNRINEFSI 330
+ LS+N +T+ + + F LL LDLS N+L +PP + N+ L ++ N + +
Sbjct: 457 LNLSYNRITSPQVHRDAFRKLRLLRSLDLSGNRLHTLPPGLPRNVHVLKVKRNELAALAR 516
Query: 331 SSFCTVVDVVNFSKLQVLRLDGNEIKRSAMPADAPLCLRLASLIEI 376
+ +V ++L+ L L N ++ A+ A + L L++I
Sbjct: 517 GA------LVGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLLDI 556
Score = 115 bits (287), Expect = 8e-26
Identities = 88/304 (28%), Positives = 143/304 (47%), Gaps = 18/304 (5%)
Query: 67 SPSPPDPR----DCPQECDCPPNFPTAMYCDNRNLKYLPF-VPSRMKYVYFQNNQITSIQ 121
SP P P CP++C C + C +L+ P +P ++ QNNQ+ I
Sbjct: 103 SPEEPGPGPAAVSCPRDCACSQE--GVVDCGGIDLREFPGDLPEHTNHLSLQNNQLEKIY 160
Query: 122 EGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLPRSLREL 181
L + L N++TS + K F L +L LYL +N LT P LP +L +
Sbjct: 161 PEELSRLHRLETLNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLTLAPRFLPNALISV 220
Query: 182 HLDHNQISRVPNNALEGLENLTALYLQHNEIQEVG---SSMRGLRSLILLDLSYNHLRKV 238
N ++++ NL ++YL +N++ + G + G ++ +L LS N LR V
Sbjct: 221 DFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHV 280
Query: 239 PDGLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNTF-NSSSLLE 297
P LP AL +L++++N + +P F L + L +N LT+ GL + TF SSL
Sbjct: 281 PKHLPPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEY 340
Query: 298 LDLSYNQLQKIPP-VNTNLENLYLQGNRINEFSISSFCTVVDVVNFSKLQVLRLDGNEIK 356
LDLS N L ++P + +L L+L+ N I + + L+ L L N+++
Sbjct: 341 LDLSSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPI------RSLEYLLLHSNQLR 394
Query: 357 RSAM 360
+
Sbjct: 395 EQGI 398
Score = 107 bits (266), Expect = 2e-23
Identities = 86/293 (29%), Positives = 135/293 (46%), Gaps = 12/293 (4%)
Query: 90 MYCDNRNLKYLP-FVPSRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGR 148
+Y N L P F+P+ + V F N +T I F L + LH N++ +
Sbjct: 199 LYLANNKLTLAPRFLPNALISVDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPD 258
Query: 149 KVFSKLRHLERLYLDHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQ 208
+F+ ++E L L N L +P LP +L +LHL +N++ ++P A L +L LYLQ
Sbjct: 259 NMFNGSSNVEVLILSSNFLRHVPKHLPPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQ 318
Query: 209 HNEIQEVG---SSMRGLRSLILLDLSYNHLRKVPDGLPSALEQLYMEHNNVYTVPDSYFR 265
+N + + G + L SL LDLS N+L +VP GLP +L L++E N + +V +
Sbjct: 319 NNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLT 378
Query: 266 GAPKLLYVRLSHNSLTNNGLASNTFNSSSLLE-LDLSYNQLQKIPP-VNTNLENLYLQGN 323
L Y+ L N L G+ F L + L N L+++P + + L + N
Sbjct: 379 PIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGLPRRVRTLMILHN 438
Query: 324 RINEFSISSFCTVVDVVNFSKLQVLRLDGNEIKRSAMPADAPLCLRLASLIEI 376
+I F T L+ L L N I + DA LRL +++
Sbjct: 439 QITGIGREDFATTY------FLEELNLSYNRITSPQVHRDAFRKLRLLRSLDL 485
Score = 105 bits (263), Expect = 5e-23
Identities = 72/215 (33%), Positives = 109/215 (50%), Gaps = 5/215 (2%)
Query: 94 NRNLKYLPF-VPSRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFS 152
N L+ +P +P R++ + +NQIT I F L + L N+ITS +V R F
Sbjct: 416 NNALERVPSGLPRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRITSPQVHRDAFR 475
Query: 153 KLRHLERLYLDHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEI 212
KLR L L L N L +P LPR++ L + N+++ + AL G+ L LYL N +
Sbjct: 476 KLRLLRSLDLSGNRLHTLPPGLPRNVHVLKVKRNELAALARGALVGMAQLRELYLTSNRL 535
Query: 213 QEVGSSMRG---LRSLILLDLSYNHLRKVPDGLPSALEQLYMEHNNVYTVPDSYFRGAPK 269
+ R L L LLD++ N L ++P+GLP +LE LY+++N + VP + F P
Sbjct: 536 RSRALGPRAWVDLAHLQLLDIAGNQLTEIPEGLPESLEYLYLQNNKISAVPANAFDSTPN 595
Query: 270 LLYVRLSHNSLTNNGLASNTFNSSSLLE-LDLSYN 303
L + L N L + + F L+ LD+ N
Sbjct: 596 LKGIFLRFNKLAVGSVVDSAFRRLKHLQVLDIEGN 630
Score = 102 bits (254), Expect = 6e-22
Identities = 79/264 (29%), Positives = 129/264 (48%), Gaps = 10/264 (3%)
Query: 94 NRNLKYLPF-VPSRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFS 152
+ NL +P +P + ++ + N I S+ V L ++ LH NQ+ + F
Sbjct: 345 SNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQ 404
Query: 153 KLRHLERLYLDHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEI 212
L+ L ++L +N L R+P LPR +R L + HNQI+ + L L L +N I
Sbjct: 405 GLKRLHTVHLYNNALERVPSGLPRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRI 464
Query: 213 ---QEVGSSMRGLRSLILLDLSYNHLRKVPDGLPSALEQLYMEHNNVYTVPDSYFRGAPK 269
Q + R LR L LDLS N L +P GLP + L ++ N + + G +
Sbjct: 465 TSPQVHRDAFRKLRLLRSLDLSGNRLHTLPPGLPRNVHVLKVKRNELAALARGALVGMAQ 524
Query: 270 LLYVRLSHNSLTNNGLASNTFNSSSLLEL-DLSYNQLQKIPP-VNTNLENLYLQGNRINE 327
L + L+ N L + L + + L+L D++ NQL +IP + +LE LYLQ N+I+
Sbjct: 525 LRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIPEGLPESLEYLYLQNNKISA 584
Query: 328 FSISSFCTVVDV----VNFSKLQV 347
++F + ++ + F+KL V
Sbjct: 585 VPANAFDSTPNLKGIFLRFNKLAV 608
>gi|226342935 podocan-like 1 isoform 3 [Homo sapiens]
Length = 421
Score = 117 bits (292), Expect = 2e-26
Identities = 86/276 (31%), Positives = 126/276 (45%), Gaps = 26/276 (9%)
Query: 56 GVDEGPAYTYGSPSPPDPRDCPQECDCPPNFPTAMYCDNRNLKYLPFVPSRM-KYVYFQN 114
G+++ G P PR CP C CP + CD +L+ P +R +++ QN
Sbjct: 24 GLEDAAFPHLGESLQPLPRACPLRCSCPR--VDTVDCDGLDLRVFPDNITRAAQHLSLQN 81
Query: 115 NQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPL 174
NQ+ + +GL + LH N I+S+ + + F L L+ L + HN
Sbjct: 82 NQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAHNK-------- 133
Query: 175 PRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVG---SSMRGLRSLILLDLS 231
+N IS+VP AL L LYLQHN++ + G ++ L SL LDLS
Sbjct: 134 ----------NNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLS 183
Query: 232 YNHLRKVPDGLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNTFN 291
+N L VP GLP L L++ N + V + GA L Y+ L HN L ++GL +
Sbjct: 184 HNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALR 243
Query: 292 S-SSLLELDLSYNQLQKIPP-VNTNLENLYLQGNRI 325
L L L N L ++PP + L L L N +
Sbjct: 244 PLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHV 279
Score = 115 bits (289), Expect = 5e-26
Identities = 79/218 (36%), Positives = 109/218 (50%), Gaps = 5/218 (2%)
Query: 113 QNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPG 172
+NN I+ + G T L + L NQ+T + FSKL LE L L HN LT +P
Sbjct: 133 KNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPA 192
Query: 173 PLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVG---SSMRGLRSLILLD 229
LPR+L LHL N+I +V L G L L LQHN++ G ++R LR L L
Sbjct: 193 GLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLH 252
Query: 230 LSYNHLRKVPDGLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNT 289
L N L +VP LP L L + HN+V + P L + L++N L + +
Sbjct: 253 LYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRA 312
Query: 290 FNS-SSLLELDLSYNQLQKIP-PVNTNLENLYLQGNRI 325
F +L LDL+ NQL ++P + T L L LQ N++
Sbjct: 313 FRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQL 350
Score = 89.4 bits (220), Expect = 5e-18
Identities = 58/199 (29%), Positives = 94/199 (47%), Gaps = 3/199 (1%)
Query: 103 VPSRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYL 162
+P + ++ N+I ++ A GL ++ L NQ+ S + LR L L+L
Sbjct: 194 LPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHL 253
Query: 163 DHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEV---GSSM 219
N L R+P LPR LR L L HN ++ + L LT L L +N + +
Sbjct: 254 YGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAF 313
Query: 220 RGLRSLILLDLSYNHLRKVPDGLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNS 279
R LR+L LDL+ N L ++P GLP+ L L ++ N + + G +L + L+HN
Sbjct: 314 RRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNR 373
Query: 280 LTNNGLASNTFNSSSLLEL 298
L + T++ L++
Sbjct: 374 LRVGDIGPGTWHELQALQV 392
Score = 63.9 bits (154), Expect = 2e-10
Identities = 37/113 (32%), Positives = 57/113 (50%)
Query: 101 PFVPSRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERL 160
P +P R++ + +N + ++ GL + L N++ S +V + F +LR L L
Sbjct: 263 PALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAFRRLRALRSL 322
Query: 161 YLDHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQ 213
L N LTR+P LP LR L L NQ+ + L GL+ L L L HN ++
Sbjct: 323 DLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRLR 375
>gi|4502403 biglycan preproprotein [Homo sapiens]
Length = 368
Score = 113 bits (283), Expect = 2e-25
Identities = 93/333 (27%), Positives = 147/333 (44%), Gaps = 25/333 (7%)
Query: 9 LAGLFSLSQAQYEDDPHWWFHYLRSQQSTYYDPYDPYPYETYEPYPYGVDEGPAYTYGSP 68
L L +LSQA + +W L D P+ + G D S
Sbjct: 7 LVSLLALSQALPFEQRGFWDFTL-----------DDGPFMMNDEEASGADTSGVLDPDSV 55
Query: 69 SPPDPRDCPQECDCPPNFPTAMYCDNRNLKYLPF-VPSRMKYVYFQNNQITSIQEGVFDN 127
+P CP C C + C + LK +P + + QNN I+ +++ F
Sbjct: 56 TPTYSAMCPFGCHCHLR---VVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKG 112
Query: 128 ATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLPRSLRELHLDHNQ 187
L + L N+I+ K+ K FS LR L++LY+ N+L +P LP SL EL + N+
Sbjct: 113 LQHLYALVLVNNKIS--KIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNR 170
Query: 188 ISRVPNNALEGLENLTALYLQHNEIQEVG---SSMRGLRSLILLDLSYNHLRKVPDGLPS 244
I +VP GL N+ + + N ++ G + GL+ L L +S L +P LP
Sbjct: 171 IRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLK-LNYLRISEAKLTGIPKDLPE 229
Query: 245 ALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNTFNSSSLLELDLSYNQ 304
L +L+++HN + + KL + L HN + S +F +L EL L N+
Sbjct: 230 TLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSF-LPTLRELHLDNNK 288
Query: 305 LQKIP---PVNTNLENLYLQGNRINEFSISSFC 334
L ++P P L+ +YL N I + ++ FC
Sbjct: 289 LARVPSGLPDLKLLQVVYLHSNNITKVGVNDFC 321
>gi|225579152 insulin-like growth factor binding protein, acid
labile subunit isoform 1 precursor [Homo sapiens]
Length = 643
Score = 92.8 bits (229), Expect = 4e-19
Identities = 97/331 (29%), Positives = 151/331 (45%), Gaps = 50/331 (15%)
Query: 66 GSPSPPDPRDCPQECDCPPNFPT---AMYCDNRNLKYLPF-VPSRMKYVYFQNNQITSIQ 121
G+P + CP C C + +++C +RNL LP VP + ++ N ++S+
Sbjct: 69 GTPGEAEGPACPAACVCSYDDDADELSVFCSSRNLTRLPDGVPGGTQALWLDGNNLSSVP 128
Query: 122 EGVFDNATGLLWIALHGNQITSDK----VGRKVFSKLRHLER------------------ 159
F N + L ++ L G Q+ S + +G + L HLER
Sbjct: 129 PAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHL-HLERNQLRSLALGTFAHTPALA 187
Query: 160 -LYLDHNNLTRMPGPLPR---SLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEV 215
L L +N L+R+ L SL +L+L N ++ +P+ A GL +L L L N + +
Sbjct: 188 SLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYL 247
Query: 216 GSSM-RGLRSLILLDLSYNHLRKVPDG----LPSALEQLYMEHNNVYTVPDSYFRGAPKL 270
++ GL L LDLS N LR + LP L++LY++ N + V F G L
Sbjct: 248 QPALFSGLAELRELDLSRNALRAIKANVFVQLP-RLQKLYLDRNLIAAVAPGAFLGLKAL 306
Query: 271 LYVRLSHNSLTNNGLASNTF-NSSSLLELDLSYNQLQKIPPVNTN----LENLYLQGNRI 325
++ LSHN + GL +TF L L LS+N + + P LE L L NRI
Sbjct: 307 RWLDLSHNRVA--GLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRI 364
Query: 326 NEFSISSFCTVVDVVNFSKLQVLRLDGNEIK 356
+ + SF +L+VL LD N+++
Sbjct: 365 RQLAERSF------EGLGQLEVLTLDHNQLQ 389
Score = 83.6 bits (205), Expect = 3e-16
Identities = 73/238 (30%), Positives = 114/238 (47%), Gaps = 24/238 (10%)
Query: 106 RMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHN 165
R++ +Y N I ++ G F L W+ L N++ + F L L L L HN
Sbjct: 281 RLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAG--LLEDTFPGLLGLRVLRLSHN 338
Query: 166 NLTRMPGPLPRSLRELH------LDHNQISRVPNNALEGLENLTALYLQHNEIQEV-GSS 218
+ + PR+ ++LH L HN+I ++ + EGL L L L HN++QEV +
Sbjct: 339 AIASLR---PRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGA 395
Query: 219 MRGLRSLILLDLSYNHLRKVPD----GLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVR 274
GL ++ +++LS N LR +P+ GL L L++E + + + F G L +
Sbjct: 396 FLGLTNVAVMNLSGNCLRNLPEQVFRGL-GKLHSLHLEGSCLGRIRPHTFTGLSGLRRLF 454
Query: 275 LSHNSLTNNGLASNT-FNSSSLLELDLSYNQLQKIP----PVNTNLENLYLQGNRINE 327
L N L G+ + + + LLELDL+ NQL +P LE L L NR+ E
Sbjct: 455 LKDNGLV--GIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAE 510
Score = 54.7 bits (130), Expect = 1e-07
Identities = 49/182 (26%), Positives = 87/182 (47%), Gaps = 9/182 (4%)
Query: 106 RMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHN 165
+++ + +NQ+ ++ G F T + + L GN + + + +VF L L L+L+ +
Sbjct: 377 QLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRN--LPEQVFRGLGKLHSLHLEGS 434
Query: 166 NLTRM-PGPLP--RSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVGSSM-RG 221
L R+ P LR L L N + + +L GL L L L N++ + + +G
Sbjct: 435 CLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQG 494
Query: 222 LRSLILLDLSYNHLRKVPDGLPSALEQLY---MEHNNVYTVPDSYFRGAPKLLYVRLSHN 278
L L L LS N L ++P L++ + + HN + +P+S +L Y+ L +N
Sbjct: 495 LGKLEYLLLSRNRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNN 554
Query: 279 SL 280
SL
Sbjct: 555 SL 556
Score = 50.4 bits (119), Expect = 3e-06
Identities = 38/127 (29%), Positives = 62/127 (48%), Gaps = 7/127 (5%)
Query: 105 SRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDH 164
S ++ ++ ++N + I+E LL + L NQ+T + ++F L LE L L
Sbjct: 448 SGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTH--LPHRLFQGLGKLEYLLLSR 505
Query: 165 NNLTRMP----GPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVGSSMR 220
N L +P GPL R+ L + HN++ +PN+ L L L L L++N ++
Sbjct: 506 NRLAELPADALGPLQRAFW-LDVSHNRLEALPNSLLAPLGRLRYLSLRNNSLRTFTPQPP 564
Query: 221 GLRSLIL 227
GL L L
Sbjct: 565 GLERLWL 571
>gi|4826772 insulin-like growth factor binding protein, acid labile
subunit isoform 2 precursor [Homo sapiens]
Length = 605
Score = 92.8 bits (229), Expect = 4e-19
Identities = 97/331 (29%), Positives = 151/331 (45%), Gaps = 50/331 (15%)
Query: 66 GSPSPPDPRDCPQECDCPPNFPT---AMYCDNRNLKYLPF-VPSRMKYVYFQNNQITSIQ 121
G+P + CP C C + +++C +RNL LP VP + ++ N ++S+
Sbjct: 31 GTPGEAEGPACPAACVCSYDDDADELSVFCSSRNLTRLPDGVPGGTQALWLDGNNLSSVP 90
Query: 122 EGVFDNATGLLWIALHGNQITSDK----VGRKVFSKLRHLER------------------ 159
F N + L ++ L G Q+ S + +G + L HLER
Sbjct: 91 PAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHL-HLERNQLRSLALGTFAHTPALA 149
Query: 160 -LYLDHNNLTRMPGPLPR---SLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEV 215
L L +N L+R+ L SL +L+L N ++ +P+ A GL +L L L N + +
Sbjct: 150 SLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYL 209
Query: 216 GSSM-RGLRSLILLDLSYNHLRKVPDG----LPSALEQLYMEHNNVYTVPDSYFRGAPKL 270
++ GL L LDLS N LR + LP L++LY++ N + V F G L
Sbjct: 210 QPALFSGLAELRELDLSRNALRAIKANVFVQLP-RLQKLYLDRNLIAAVAPGAFLGLKAL 268
Query: 271 LYVRLSHNSLTNNGLASNTF-NSSSLLELDLSYNQLQKIPPVNTN----LENLYLQGNRI 325
++ LSHN + GL +TF L L LS+N + + P LE L L NRI
Sbjct: 269 RWLDLSHNRVA--GLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRI 326
Query: 326 NEFSISSFCTVVDVVNFSKLQVLRLDGNEIK 356
+ + SF +L+VL LD N+++
Sbjct: 327 RQLAERSF------EGLGQLEVLTLDHNQLQ 351
Score = 83.6 bits (205), Expect = 3e-16
Identities = 73/238 (30%), Positives = 114/238 (47%), Gaps = 24/238 (10%)
Query: 106 RMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHN 165
R++ +Y N I ++ G F L W+ L N++ + F L L L L HN
Sbjct: 243 RLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAG--LLEDTFPGLLGLRVLRLSHN 300
Query: 166 NLTRMPGPLPRSLRELH------LDHNQISRVPNNALEGLENLTALYLQHNEIQEV-GSS 218
+ + PR+ ++LH L HN+I ++ + EGL L L L HN++QEV +
Sbjct: 301 AIASLR---PRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGA 357
Query: 219 MRGLRSLILLDLSYNHLRKVPD----GLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVR 274
GL ++ +++LS N LR +P+ GL L L++E + + + F G L +
Sbjct: 358 FLGLTNVAVMNLSGNCLRNLPEQVFRGL-GKLHSLHLEGSCLGRIRPHTFTGLSGLRRLF 416
Query: 275 LSHNSLTNNGLASNT-FNSSSLLELDLSYNQLQKIP----PVNTNLENLYLQGNRINE 327
L N L G+ + + + LLELDL+ NQL +P LE L L NR+ E
Sbjct: 417 LKDNGLV--GIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAE 472
Score = 54.7 bits (130), Expect = 1e-07
Identities = 49/182 (26%), Positives = 87/182 (47%), Gaps = 9/182 (4%)
Query: 106 RMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHN 165
+++ + +NQ+ ++ G F T + + L GN + + + +VF L L L+L+ +
Sbjct: 339 QLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRN--LPEQVFRGLGKLHSLHLEGS 396
Query: 166 NLTRM-PGPLP--RSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVGSSM-RG 221
L R+ P LR L L N + + +L GL L L L N++ + + +G
Sbjct: 397 CLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQG 456
Query: 222 LRSLILLDLSYNHLRKVPDGLPSALEQLY---MEHNNVYTVPDSYFRGAPKLLYVRLSHN 278
L L L LS N L ++P L++ + + HN + +P+S +L Y+ L +N
Sbjct: 457 LGKLEYLLLSRNRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNN 516
Query: 279 SL 280
SL
Sbjct: 517 SL 518
Score = 50.4 bits (119), Expect = 3e-06
Identities = 38/127 (29%), Positives = 62/127 (48%), Gaps = 7/127 (5%)
Query: 105 SRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDH 164
S ++ ++ ++N + I+E LL + L NQ+T + ++F L LE L L
Sbjct: 410 SGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTH--LPHRLFQGLGKLEYLLLSR 467
Query: 165 NNLTRMP----GPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVGSSMR 220
N L +P GPL R+ L + HN++ +PN+ L L L L L++N ++
Sbjct: 468 NRLAELPADALGPLQRAFW-LDVSHNRLEALPNSLLAPLGRLRYLSLRNNSLRTFTPQPP 526
Query: 221 GLRSLIL 227
GL L L
Sbjct: 527 GLERLWL 533
>gi|7662320 leucine-rich repeats and immunoglobulin-like domains 2
[Homo sapiens]
Length = 1065
Score = 90.9 bits (224), Expect = 2e-18
Identities = 84/275 (30%), Positives = 138/275 (50%), Gaps = 27/275 (9%)
Query: 97 LKYLPFVPSRMKYVYFQNNQITSIQEGVFDN-ATGLLWIALHGNQITSDKVGRKVFSKLR 155
+K F ++KY+ NN+IT+++ G FDN ++ LL + L+ N+++ + K+F KL
Sbjct: 159 IKTSSFPRMQLKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRMSM--IPPKIF-KLP 215
Query: 156 HLERLYLDHNNLTRMPGPLPR---SLRELHLDHNQISRVPNNALEGLENLTALYLQHNEI 212
HL+ L L N + + G + SLR L + N IS++ + A GL N+ L L+HN +
Sbjct: 216 HLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNL 275
Query: 213 QEVGSS-MRGLRSLILLDLSYNHLRKV-PDG--LPSALEQLYMEHNNVYTVPDSYFRGAP 268
V + GLR L L +S N + ++ PD L +L + +N + + +S F G
Sbjct: 276 TRVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLS 335
Query: 269 KLLYVRLSHNSLTNNGLASNTFN-SSSLLELDLSYNQLQ-KIPPVN------TNLENLYL 320
L + L N +T+ +A F S+L LDL N++ I + T+L L L
Sbjct: 336 LLERLNLGDNRVTH--IADGVFRFLSNLQTLDLRNNEISWAIEDASEAFAGLTSLTKLIL 393
Query: 321 QGNRINEFSISSFCTVVDVVNFSKLQVLRLDGNEI 355
QGN+I + +F + L+ L L+ N I
Sbjct: 394 QGNQIKSITKKAF------IGLESLEHLDLNNNAI 422
Score = 47.0 bits (110), Expect = 3e-05
Identities = 54/203 (26%), Positives = 92/203 (45%), Gaps = 27/203 (13%)
Query: 160 LYLDHNNLTRMPGPLP-RSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVGSS 218
L HN L+ L ++L+E+ +++N+++ +P E N+T L L HN I E+ +
Sbjct: 80 LDFSHNRLSNWNISLESQTLQEVKMNYNELTEIPYFG-EPTSNITLLSLVHNIIPEINAQ 138
Query: 219 MRGLRSLILLDLSYNHLRKVPDGLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHN 278
L+ P ALE L + N + + S F +L Y+ LS+N
Sbjct: 139 A---------------LQFYP-----ALESLDLSSNIISEIKTSSFPRM-QLKYLNLSNN 177
Query: 279 SLTNNGLASNTFN--SSSLLELDLSYNQLQKIPPVNTNLENLYLQGNRINEFSISSFCTV 336
+T L + F+ SSSLL + L+ N++ IPP L +L + N I T
Sbjct: 178 RITT--LEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFKLPHLQFLELKRNRIKIVEGLTF 235
Query: 337 VDVVNFSKLQVLRLDGNEIKRSA 359
+ + L++ R +++K A
Sbjct: 236 QGLDSLRSLKMQRNGISKLKDGA 258
Score = 40.4 bits (93), Expect = 0.003
Identities = 41/131 (31%), Positives = 59/131 (45%), Gaps = 11/131 (8%)
Query: 106 RMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHN 165
R+ + NQ+T + E F + L + L N++T G VF L +L+ L L +N
Sbjct: 312 RLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADG--VFRFLSNLQTLDLRNN 369
Query: 166 NLTRMPGPLPR------SLRELHLDHNQISRVPNNALEGLENLTALYLQHN---EIQEVG 216
++ SL +L L NQI + A GLE+L L L +N IQE
Sbjct: 370 EISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNNNAIMSIQENA 429
Query: 217 SSMRGLRSLIL 227
S L+ LIL
Sbjct: 430 FSQTHLKELIL 440
>gi|157694513 leucine-rich repeat-containing G protein-coupled
receptor 4 [Homo sapiens]
Length = 951
Score = 89.7 bits (221), Expect = 4e-18
Identities = 74/229 (32%), Positives = 118/229 (51%), Gaps = 12/229 (5%)
Query: 107 MKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNN 166
+K + QNNQ+ ++ + L + L N ITS V F L L L+LD N+
Sbjct: 107 LKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITS--VPEDSFEGLVQLRHLWLDDNS 164
Query: 167 LTRMP-GPLPR--SLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVGS-SMRGL 222
LT +P PL +L+ L L N+IS +P+ A L +L L+L +N+I+ + GL
Sbjct: 165 LTEVPVHPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGL 224
Query: 223 RSLILLDLSYNHLRKVPDGLPS--ALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSL 280
+L LDL+YN+L + P + + +L++L N++ +PD F G P L + L N L
Sbjct: 225 DNLETLDLNYNNLGEFPQAIKALPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPL 284
Query: 281 TNNGLASNTFNSSSLLELDL-SYNQLQKIPPV--NTNLENLYLQGNRIN 326
+ G S N S L L + + +Q+ P + +LE+L L G +I+
Sbjct: 285 SFVG-NSAFHNLSDLHSLVIRGASMVQQFPNLTGTVHLESLTLTGTKIS 332
Score = 78.2 bits (191), Expect = 1e-14
Identities = 79/284 (27%), Positives = 123/284 (43%), Gaps = 18/284 (6%)
Query: 68 PSPPDPRDCPQECDCPPNFPTAMYCDNRNLKYLPFVPSRMKYVY-FQNNQITSIQEGVFD 126
PS P C C C + + C + L +P S N IT + E F
Sbjct: 21 PSGAAPPLCAAPCSCDGD--RRVDCSGKGLTAVPEGLSAFTQALDISMNNITQLPEDAFK 78
Query: 127 NATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLPR---SLRELHL 183
N L + L GN ++ + K S L+ L+ L L +N L +P R +L+ L L
Sbjct: 79 NFPFLEELQLAGNDLSF--IHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRL 136
Query: 184 DHNQISRVPNNALEGLENLTALYLQHNEIQEVG-SSMRGLRSLILLDLSYNHLRKVPDGL 242
D N I+ VP ++ EGL L L+L N + EV + L +L L L+ N + +PD
Sbjct: 137 DANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFA 196
Query: 243 ---PSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNTFNSSSLLELD 299
S+L L++ +N + ++ F G L + L++N+L A SL EL
Sbjct: 197 FTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEFPQAIKAL--PSLKELG 254
Query: 300 LSYNQLQKIP----PVNTNLENLYLQGNRINEFSISSFCTVVDV 339
N + IP N L ++L N ++ S+F + D+
Sbjct: 255 FHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDL 298
Score = 46.6 bits (109), Expect = 4e-05
Identities = 40/135 (29%), Positives = 64/135 (47%), Gaps = 7/135 (5%)
Query: 125 FDNATGLLWI---ALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLP-RSLRE 180
F N TG + + L G +I+S + + + + L L L +NN+ +P +L E
Sbjct: 312 FPNLTGTVHLESLTLTGTKISS--IPNNLCQEQKMLRTLDLSYNNIRDLPSFNGCHALEE 369
Query: 181 LHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVGS-SMRGLRSLILLDLSYNHLRKVP 239
+ L NQI ++ +GL +L L L N I E+ S + L + LD+S+N L P
Sbjct: 370 ISLQRNQIYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFATLGPITNLDVSFNELTSFP 429
Query: 240 DGLPSALEQLYMEHN 254
+ L QL + N
Sbjct: 430 TEGLNGLNQLKLVGN 444
Score = 37.7 bits (86), Expect = 0.017
Identities = 37/132 (28%), Positives = 61/132 (46%), Gaps = 11/132 (8%)
Query: 228 LDLSYNHLRKVPDGLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLAS 287
+D S L VP+GL + + L + NN+ +P+ F+ P L ++L+ N L+ +
Sbjct: 41 VDCSGKGLTAVPEGLSAFTQALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKA 100
Query: 288 NTFNSSSLLELDLSYNQLQKIPPVN----TNLENLYLQGNRINEFSISSFCTVVDVVNFS 343
+ L L L NQL+ +P + L++L L N I SF +V
Sbjct: 101 LS-GLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLV------ 153
Query: 344 KLQVLRLDGNEI 355
+L+ L LD N +
Sbjct: 154 QLRHLWLDDNSL 165
>gi|40255157 leucine-rich repeats and immunoglobulin-like domains 3
isoform 2 [Homo sapiens]
Length = 1119
Score = 89.4 bits (220), Expect = 5e-18
Identities = 86/291 (29%), Positives = 145/291 (49%), Gaps = 25/291 (8%)
Query: 102 FVPSRMKYVYFQNNQITSIQEGVFDN-ATGLLWIALHGNQITSDKVGRKVFSKLRHLERL 160
F ++KY+Y +N++TS++ G FDN A LL + L+ N+I++ + K+F KL L+ L
Sbjct: 164 FPALQLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISA--IPPKMF-KLPQLQHL 220
Query: 161 YLDHNNLTRMPGPLPR---SLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVGS 217
L+ N + + G + +L+ L + N ++++ + A GL N+ L L HN + E+
Sbjct: 221 ELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITK 280
Query: 218 S-MRGLRSLILLDLSYNHLRKV-PDG--LPSALEQLYMEHNNVYTVPDSYFRGAPKLLYV 273
+ GL L L LS N + ++ PD L +L + N++ + DS F G L +
Sbjct: 281 GWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTL 340
Query: 274 RLSHNSLTNNGLASNTFNS-SSLLELDLSYNQLQ-KIPPVN------TNLENLYLQGNRI 325
+ +N ++ +A F SSL LDL N++ I +N L L LQGNRI
Sbjct: 341 HIGNNRVSY--IADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRI 398
Query: 326 NEFSISSF--CTVVDVVNFSKLQVLRLDGNEIKRSAMPADAPLCLRLASLI 374
+ +F ++ ++ S ++ L GN S M L L +SL+
Sbjct: 399 RSITKKAFTGLDALEHLDLSDNAIMSLQGNAF--SQMKKLQQLHLNTSSLL 447
Score = 64.3 bits (155), Expect = 2e-10
Identities = 58/219 (26%), Positives = 102/219 (46%), Gaps = 38/219 (17%)
Query: 167 LTRMPGPLPRSLRELHLDHNQIS----------------RVPNNALEGLENL-------T 203
L R+P PLP + L L HN++S ++ NN LE + NL T
Sbjct: 65 LARLPEPLPSWVARLDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIPNLGPVSANIT 124
Query: 204 ALYLQHNEIQEV-GSSMRGLRSLILLDLSYNHLRKVPDGLPS-ALEQLYMEHNNVYTVPD 261
L L N I E+ ++ +SL LDLS N++ ++ P+ L+ LY+ N V ++
Sbjct: 125 LLSLAGNRIVEILPEHLKEFQSLETLDLSSNNISELQTAFPALQLKYLYLNSNRVTSMEP 184
Query: 262 SYFRG-APKLLYVRLSHNSLTNNGLASNTFNSSSLLELDLSYNQLQKIPPVNTN----LE 316
YF A LL ++L+ N + + + F L L+L+ N+++ + + L+
Sbjct: 185 GYFDNLANTLLVLKLNRNRI--SAIPPKMFKLPQLQHLELNRNKIKNVDGLTFQGLGALK 242
Query: 317 NLYLQGNRINEFSISSFCTVVDVVNFSKLQVLRLDGNEI 355
+L +Q N + + +F S +++L+LD N +
Sbjct: 243 SLKMQRNGVTKLMDGAFW------GLSNMEILQLDHNNL 275
Score = 44.7 bits (104), Expect = 1e-04
Identities = 42/141 (29%), Positives = 64/141 (45%), Gaps = 36/141 (25%)
Query: 227 LLDLSYNHLRKVPDGLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLA 286
LLD S L ++P+ LPS + +L + HN +L +++ A
Sbjct: 57 LLDCSRKRLARLPEPLPSWVARLDLSHN--------------RLSFIK-----------A 91
Query: 287 SNTFNSSSLLELDLSYNQLQKIP---PVNTNLENLYLQGNRINEFSISSFCTVVDVVNFS 343
S+ + SL E+ L+ N+L+ IP PV+ N+ L L GNRI E + F
Sbjct: 92 SSMSHLQSLREVKLNNNELETIPNLGPVSANITLLSLAGNRIVEI------LPEHLKEFQ 145
Query: 344 KLQVLRLDGNEIK--RSAMPA 362
L+ L L N I ++A PA
Sbjct: 146 SLETLDLSSNNISELQTAFPA 166
>gi|209862903 leucine-rich repeats and immunoglobulin-like domains 3
isoform 1 [Homo sapiens]
Length = 1059
Score = 89.4 bits (220), Expect = 5e-18
Identities = 86/291 (29%), Positives = 145/291 (49%), Gaps = 25/291 (8%)
Query: 102 FVPSRMKYVYFQNNQITSIQEGVFDN-ATGLLWIALHGNQITSDKVGRKVFSKLRHLERL 160
F ++KY+Y +N++TS++ G FDN A LL + L+ N+I++ + K+F KL L+ L
Sbjct: 104 FPALQLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISA--IPPKMF-KLPQLQHL 160
Query: 161 YLDHNNLTRMPGPLPR---SLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVGS 217
L+ N + + G + +L+ L + N ++++ + A GL N+ L L HN + E+
Sbjct: 161 ELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITK 220
Query: 218 S-MRGLRSLILLDLSYNHLRKV-PDG--LPSALEQLYMEHNNVYTVPDSYFRGAPKLLYV 273
+ GL L L LS N + ++ PD L +L + N++ + DS F G L +
Sbjct: 221 GWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTL 280
Query: 274 RLSHNSLTNNGLASNTFNS-SSLLELDLSYNQLQ-KIPPVN------TNLENLYLQGNRI 325
+ +N ++ +A F SSL LDL N++ I +N L L LQGNRI
Sbjct: 281 HIGNNRVSY--IADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRI 338
Query: 326 NEFSISSF--CTVVDVVNFSKLQVLRLDGNEIKRSAMPADAPLCLRLASLI 374
+ +F ++ ++ S ++ L GN S M L L +SL+
Sbjct: 339 RSITKKAFTGLDALEHLDLSDNAIMSLQGNAF--SQMKKLQQLHLNTSSLL 387
Score = 51.6 bits (122), Expect = 1e-06
Identities = 51/203 (25%), Positives = 93/203 (45%), Gaps = 38/203 (18%)
Query: 183 LDHNQIS----------------RVPNNALEGLENL-------TALYLQHNEIQEV-GSS 218
L HN++S ++ NN LE + NL T L L N I E+
Sbjct: 21 LSHNRLSFIKASSMSHLQSLREVKLNNNELETIPNLGPVSANITLLSLAGNRIVEILPEH 80
Query: 219 MRGLRSLILLDLSYNHLRKVPDGLPS-ALEQLYMEHNNVYTVPDSYFRG-APKLLYVRLS 276
++ +SL LDLS N++ ++ P+ L+ LY+ N V ++ YF A LL ++L+
Sbjct: 81 LKEFQSLETLDLSSNNISELQTAFPALQLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLN 140
Query: 277 HNSLTNNGLASNTFNSSSLLELDLSYNQLQKIPPVNTN----LENLYLQGNRINEFSISS 332
N + + + F L L+L+ N+++ + + L++L +Q N + + +
Sbjct: 141 RNRI--SAIPPKMFKLPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGA 198
Query: 333 FCTVVDVVNFSKLQVLRLDGNEI 355
F S +++L+LD N +
Sbjct: 199 FW------GLSNMEILQLDHNNL 215
Score = 51.2 bits (121), Expect = 1e-06
Identities = 63/234 (26%), Positives = 105/234 (44%), Gaps = 24/234 (10%)
Query: 152 SKLRHLERLYLDHNNLTRMP--GPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQH 209
S L+ L + L++N L +P GP+ ++ L L N+I + L+ ++L L L
Sbjct: 35 SHLQSLREVKLNNNELETIPNLGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSS 94
Query: 210 NEIQEVGSSMRGLRSLILLDLSYNHLRKVP----DGLPSALEQLYMEHNNVYTVPDSYFR 265
N I E+ ++ L+ L L L+ N + + D L + L L + N + +P F+
Sbjct: 95 NNISELQTAFPALQ-LKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFK 153
Query: 266 GAPKLLYVRLSHNSLTN-NGLASNTFNS-SSLLELDLSYNQLQKIPPVN----TNLENLY 319
P+L ++ L+ N + N +GL TF +L L + N + K+ +N+E L
Sbjct: 154 -LPQLQHLELNRNKIKNVDGL---TFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQ 209
Query: 320 LQGNRINEFSISSFCTVVDVVNFSKLQVLRLDGNEIKRSAMPADAPLCLRLASL 373
L N + E T + LQ L L N I R + P C +L+ L
Sbjct: 210 LDHNNLTEI------TKGWLYGLLMLQELHLSQNAINRIS-PDAWEFCQKLSEL 256
>gi|109809759 leucine rich repeat transmembrane neuronal 3 [Homo
sapiens]
Length = 581
Score = 88.6 bits (218), Expect = 8e-18
Identities = 85/296 (28%), Positives = 131/296 (44%), Gaps = 62/296 (20%)
Query: 74 RDCPQECDCPPNFPTAMYCDNRNLKYLPFVPSRMKYVYFQNNQITSIQEGVFDNATGLLW 133
R CP+ C C +YC+++ L+ +P +SI + G L
Sbjct: 32 RGCPKGCRCEGKM---VYCESQKLQEIP----------------SSI-------SAGCLG 65
Query: 134 IALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPL---PRSLRELHLDHNQISR 190
++L N + K + F L L LYLDHN+++ + R L+EL L N+IS
Sbjct: 66 LSLRYNSLQKLKYNQ--FKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISY 123
Query: 191 VPNNALEGLENLTALYLQHNEIQEVGS-SMRGLRSLILLDLSYNHLRKVPDGL---PSAL 246
NN + NL L L +N++ +GS RGLR L+ L L N LR +P + L
Sbjct: 124 FLNNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNL 183
Query: 247 EQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNTFNSSSLLELDLSYNQLQ 306
E L + +N + ++ + F G +L + L HN + LA
Sbjct: 184 ELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLA-------------------- 223
Query: 307 KIPPVNTNLENLYLQGNRINEFSISSFCTVVDVVNFSKLQVLRLDGNEIKRSAMPA 362
+ P +L+NLYLQ N+I+ + T +S LQ L L GNEI+ + P+
Sbjct: 224 -LFPRLVSLQNLYLQWNKISVIGQTMSWT------WSSLQRLDLSGNEIEAFSGPS 272
Score = 36.2 bits (82), Expect = 0.049
Identities = 32/136 (23%), Positives = 63/136 (46%), Gaps = 10/136 (7%)
Query: 106 RMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHN 165
R+K ++ ++NQ + + +F L + L N+I+ +G+ + L+RL L N
Sbjct: 206 RLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKIS--VIGQTMSWTWSSLQRLDLSGN 263
Query: 166 NLTRMPGP----LPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVGSSMRG 221
+ GP +L+ L+LD N+++ + L+ +L + L N + R
Sbjct: 264 EIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLNDISLAGN----IWECSRN 319
Query: 222 LRSLILLDLSYNHLRK 237
+ SL+ S+ LR+
Sbjct: 320 ICSLVNWLKSFKGLRE 335
Score = 32.0 bits (71), Expect = 0.93
Identities = 25/73 (34%), Positives = 40/73 (54%), Gaps = 2/73 (2%)
Query: 96 NLKYLPFVPSRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLR 155
NL P + S ++ +Y Q N+I+ I + + + L + L GN+I + G VF +
Sbjct: 221 NLALFPRLVS-LQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFS-GPSVFQCVP 278
Query: 156 HLERLYLDHNNLT 168
+L+RL LD N LT
Sbjct: 279 NLQRLNLDSNKLT 291
>gi|153251229 chondroadherin precursor [Homo sapiens]
Length = 359
Score = 87.8 bits (216), Expect = 1e-17
Identities = 82/294 (27%), Positives = 130/294 (44%), Gaps = 26/294 (8%)
Query: 76 CPQECDCPPNFPTAMYCDNRNLKYLPFVPSRMKYVYFQNNQITSIQEGVFDNATGLLWIA 135
CPQ C C + + CD L+ +P V + K + Q N + F L ++
Sbjct: 23 CPQNCHCHSDLQHVI-CDKVGLQKIPKVSEKTKLLNLQRNNFPVLAANSFRAMPNL--VS 79
Query: 136 LHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLPRSLRE---LHLDHNQISRVP 192
LH +V F L+ L LYL HN++ + L E L+LDHN+++ +P
Sbjct: 80 LHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELP 139
Query: 193 NNALEGLENLTALYLQHNEIQEV-GSSMRGLRSLILLDLSYNHLRKVPDGLPSALEQL-- 249
L L NL L L +N+I+E+ + +G + L L LS N L + G +E L
Sbjct: 140 RGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVENLAK 199
Query: 250 -YMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNTFNSSS--LLELDLSYNQLQ 306
+++ N + + P + + ++LSHN L + N F S L L L L+
Sbjct: 200 FHVDRNQLSSYPSAALSKLRVVEELKLSHNPL--KSIPDNAFQSFGRYLETLWLDNTNLE 257
Query: 307 KIPPVN----TNLENLYLQGNRINEFSISSFCTVVDVVNFSKLQVLRLDGNEIK 356
K T L++++L+ NR+N+ S+F F L+ L L N K
Sbjct: 258 KFSDGAFLGVTTLKHVHLENNRLNQLP-SNF-------PFDSLETLALTNNPWK 303
Score = 72.0 bits (175), Expect = 8e-13
Identities = 74/261 (28%), Positives = 117/261 (44%), Gaps = 44/261 (16%)
Query: 141 ITSDKVGRKVFSKLRHLERLY-LDHNNLTRMPGPLPRS---LRELHLDHNQISRVPNNAL 196
+ DKVG + K+ +L L NN + R+ L LHL H QI V A
Sbjct: 36 VICDKVGLQKIPKVSEKTKLLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAF 95
Query: 197 EGLENLTALYLQHNEIQEV-GSSMRGLRSLILLDLSYNHLRKVPDGLPSALEQLY---ME 252
GL+ L LYL HN+I+ + + L L L L +N + ++P GL S L L+ +
Sbjct: 96 RGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLN 155
Query: 253 HNNVYTVPDSYFRGAPKLLYVRLSHNSLTN-------------------NGLASNTFNSS 293
+N + + F+GA L ++ LS N+L++ N L+S +
Sbjct: 156 NNKIRELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAAL 215
Query: 294 SLL----ELDLSYNQLQKIP-----PVNTNLENLYLQGNRINEFSISSFCTVVDVVNFSK 344
S L EL LS+N L+ IP LE L+L + +FS +F V +
Sbjct: 216 SKLRVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGV------TT 269
Query: 345 LQVLRLDGNEIKRSAMPADAP 365
L+ + L+ N + + +P++ P
Sbjct: 270 LKHVHLENNRLNQ--LPSNFP 288
>gi|86990456 leucine rich repeat transmembrane neuronal 1 [Homo
sapiens]
Length = 522
Score = 87.0 bits (214), Expect = 2e-17
Identities = 84/299 (28%), Positives = 130/299 (43%), Gaps = 52/299 (17%)
Query: 70 PPDPRDCPQECDCPPNFPTAMYCDNRNLKYLPFVPSRMKYVYFQNNQITSIQEGVFDNAT 129
P P CPQ C C +YC+ NL P N +
Sbjct: 33 PAAPSGCPQLCRCEGRL---LYCEALNLTEAPH------------------------NLS 65
Query: 130 GLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLPRSLR---ELHLDHN 186
GLL ++L N ++ + G+ F+ L L LYLDHN++ + G + LR EL L N
Sbjct: 66 GLLGLSLRYNSLSELRAGQ--FTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSN 123
Query: 187 QISRVPNNALEGLENLTALYLQHNEIQEVGSSM-RGLRSLILLDLSYNHLRKVPDGL--- 242
QI+++PN + NL ++ L +N++Q + + GLR L L + N ++ VP +
Sbjct: 124 QITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQD 183
Query: 243 PSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNTFNSSSLLELDLSY 302
+L+ L + +N + ++ + F G KL + L HN L A + L+ L
Sbjct: 184 CRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKVNFA----HFPRLISLHSLC 239
Query: 303 NQLQKIPPVNT------NLENLYLQGNRINEFSISSFCTVVDVVNFSKLQVLRLDGNEI 355
+ K+ V + NLE + L GN I F TV LQ L+LD N +
Sbjct: 240 LRRNKVAIVVSSLDWVWNLEKMDLSGNEIEYMEPHVFETV------PHLQSLQLDSNRL 292
>gi|62912470 leucine-rich repeat-containing G protein-coupled
receptor 6 isoform 1 [Homo sapiens]
Length = 967
Score = 87.0 bits (214), Expect = 2e-17
Identities = 81/279 (29%), Positives = 127/279 (45%), Gaps = 36/279 (12%)
Query: 66 GSPSP-PDPRDCPQECDCPPN-FPTAMYCDNRNLKYLPF-VPSRMKYVYFQNNQITSIQE 122
G+P P P P CP C C + + C L +P + Y+ N +T +Q
Sbjct: 24 GAPQPGPGPTACPAPCHCQEDGIMLSADCSELGLSAVPGDLDPLTAYLDLSMNNLTELQP 83
Query: 123 GVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGP----LPRSL 178
G+F + L + L GN ++ + + FS L L+ L L +N L +P LP SL
Sbjct: 84 GLFHHLRFLEELRLSGNHLSH--IPGQAFSGLYSLKILMLQNNQLGGIPAEALWELP-SL 140
Query: 179 RELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVGSSMRGLRSLILLDLSYNHLRKV 238
+ L LD N IS VP + EGL +L L+L N + E+ +R L +L
Sbjct: 141 QSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEI--PVRALNNL------------- 185
Query: 239 PDGLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNTFNSSSLLE- 297
AL+ + + N + +PD F+ L+ + L +N + + L +++F LE
Sbjct: 186 -----PALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQH--LGTHSFEGLHNLET 238
Query: 298 LDLSYNQLQKIP-PVNT--NLENLYLQGNRINEFSISSF 333
LDL+YN+LQ+ P + T L+ L N I +F
Sbjct: 239 LDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAF 277
Score = 77.4 bits (189), Expect = 2e-14
Identities = 81/290 (27%), Positives = 125/290 (43%), Gaps = 49/290 (16%)
Query: 115 NQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPL 174
N+I+ I + F N T L+ + LH N+I +G F L +LE L L++N L P +
Sbjct: 196 NRISHIPDYAFQNLTSLVVLHLHNNRI--QHLGTHSFEGLHNLETLDLNYNKLQEFPVAI 253
Query: 175 PR--SLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVGSS-------------- 218
L+EL +N I +P A G L ++ N IQ VG S
Sbjct: 254 RTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLN 313
Query: 219 ----------MRGLRSLILLDLSYNHLRKVPDGLPSALEQLY---MEHNNVYTVPDSYFR 265
++G SL +L L+ +R +P G+ L +L + HN + +P +
Sbjct: 314 GAMDIQEFPDLKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPSLH-- 371
Query: 266 GAPKLLYVRLSHNSLTNNGLASNTFNS-SSLLELDLSYNQLQKIPP----VNTNLENLYL 320
KL + L HN + G ++TF+ SSL LDLS+N ++ I P +L L L
Sbjct: 372 RCQKLEEIGLQHNRIWEIG--ADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDL 429
Query: 321 QGNRINEFSISSFCTVVDVVNFSKLQVLRLDGNEIKRSAMPADAPLCLRL 370
N++ T + + L L+L GN A D+ LR+
Sbjct: 430 TDNQL---------TTLPLAGLGGLMHLKLKGNLALSQAFSKDSFPKLRI 470
Score = 72.0 bits (175), Expect = 8e-13
Identities = 83/305 (27%), Positives = 127/305 (41%), Gaps = 64/305 (20%)
Query: 107 MKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNN 166
+K + QNNQ+ I L + L N I+ V + F L L L+LD N
Sbjct: 116 LKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISL--VPERSFEGLSSLRHLWLDDNA 173
Query: 167 LTRMP----GPLPR-----------------------SLRELHLDHNQISRVPNNALEGL 199
LT +P LP SL LHL +N+I + ++ EGL
Sbjct: 174 LTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGL 233
Query: 200 ENLTALYLQHNEIQEVGSSMRGLRSLILLDLSYNHLRKVPD----GLPSALEQLYMEHNN 255
NL L L +N++QE ++R L L L N+++ +P+ G P L+ ++ N
Sbjct: 234 HNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNP-LLQTIHFYDNP 292
Query: 256 VYTVPDSYFRGAPKLLYVRLSHN------------------SLTNNGL----ASNTFNSS 293
+ V S F+ PKL + L+ +LT G+ +
Sbjct: 293 IQFVGRSAFQYLPKLHTLSLNGAMDIQEFPDLKGTTSLEILTLTRAGIRLLPSGMCQQLP 352
Query: 294 SLLELDLSYNQLQKIPPVN--TNLENLYLQGNRINEFSISSFCTVVDVVNFSKLQVLRLD 351
L L+LS+NQ++++P ++ LE + LQ NRI E +F S LQ L L
Sbjct: 353 RLRVLELSHNQIEELPSLHRCQKLEEIGLQHNRIWEIGADTFS------QLSSLQALDLS 406
Query: 352 GNEIK 356
N I+
Sbjct: 407 WNAIR 411
Score = 53.1 bits (126), Expect = 4e-07
Identities = 62/224 (27%), Positives = 94/224 (41%), Gaps = 34/224 (15%)
Query: 106 RMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYL--- 162
R++ + F NN I +I E F L I + N I VGR F L L L L
Sbjct: 258 RLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQF--VGRSAFQYLPKLHTLSLNGA 315
Query: 163 -DHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVGSSMRG 221
D + G SL L L I +P+ + L L L L HN+I+E+ S R
Sbjct: 316 MDIQEFPDLKGTT--SLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPSLHRC 373
Query: 222 LRSLILLDLSYNHLRKVPDGLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLT 281
+ LE++ ++HN ++ + F L + LS N++
Sbjct: 374 QK----------------------LEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAI- 410
Query: 282 NNGLASNTFNS-SSLLELDLSYNQLQKIPPVNT-NLENLYLQGN 323
+ F++ SL++LDL+ NQL +P L +L L+GN
Sbjct: 411 -RSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGGLMHLKLKGN 453
>gi|76880480 hypothetical protein LOC9865 [Homo sapiens]
Length = 811
Score = 84.7 bits (208), Expect = 1e-16
Identities = 94/302 (31%), Positives = 138/302 (45%), Gaps = 51/302 (16%)
Query: 76 CPQECDCPPNFPTAMYCDNRNLKYLP---FVPSRMKYVYFQ--NNQITSIQEGVFDNATG 130
CP+ CDC P + C NR L+ +P +PS + + N IT+I F
Sbjct: 27 CPERCDC--QHPQHLLCTNRGLRVVPKTSSLPSPHDVLTYSLGGNFITNITAFDFHRLGQ 84
Query: 131 LLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRM-PGPLP--RSLRELHLDHNQ 187
L + L NQI S + K F KL LE LYL +N L + PG L R LR L+ + N+
Sbjct: 85 LRRLDLQYNQIRS--LHPKTFEKLSRLEELYLGNNLLQALAPGTLAPLRKLRILYANGNE 142
Query: 188 ISRVPNNALEGLENLTA------------------------LYLQHNEIQEVG-SSMRGL 222
ISR+ + EGLE+L L+L+ N I+ +G ++ L
Sbjct: 143 ISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNAFAQL 202
Query: 223 RSLILLDLSYNH----LRKVPDGLP-SALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSH 277
L L+LS N LR P +L L + NN+ + F+ P+L + L
Sbjct: 203 GKLRFLNLSANELQPSLRHAATFAPLRSLSSLILSANNLQHLGPRIFQHLPRLGLLSLRG 262
Query: 278 NSLTNNGLASNTF-NSSSLLELDLSYNQLQKIP-----PVNTNLENLYLQGNRINEFSIS 331
N LT+ LA F +L EL L N+L ++P P++ +LE L L GN ++ +
Sbjct: 263 NQLTH--LAPEAFWGLEALRELRLEGNRLSQLPTALLEPLH-SLEALDLSGNELSALHPA 319
Query: 332 SF 333
+F
Sbjct: 320 TF 321
Score = 50.1 bits (118), Expect = 3e-06
Identities = 56/221 (25%), Positives = 88/221 (39%), Gaps = 53/221 (23%)
Query: 93 DNRNLKYLP---FVP-SRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGR 148
D L LP F P + Y++ ++N+I + + F L ++ L N++
Sbjct: 163 DGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNAFAQLGKLRFLNLSANELQPSLRHA 222
Query: 149 KVFSKLRHLERLYLDHNNLTRMPGP-----LPR-----------------------SLRE 180
F+ LR L L L NNL + GP LPR +LRE
Sbjct: 223 ATFAPLRSLSSLILSANNLQHL-GPRIFQHLPRLGLLSLRGNQLTHLAPEAFWGLEALRE 281
Query: 181 LHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVGSSMRGLRSLILLDLSYNHLRKVPD 240
L L+ N++S++P LE L +L AL L NE+ L ++ HL +
Sbjct: 282 LRLEGNRLSQLPTALLEPLHSLEALDLSGNELS------------ALHPATFGHLGR--- 326
Query: 241 GLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLT 281
L +L + +N + + F +P L + L N T
Sbjct: 327 -----LRELSLRNNALSALSGDIFAASPALYRLDLDGNGWT 362
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.137 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,839,788
Number of Sequences: 37866
Number of extensions: 810392
Number of successful extensions: 5050
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 197
Number of HSP's successfully gapped in prelim test: 104
Number of HSP's that attempted gapping in prelim test: 2658
Number of HSP's gapped (non-prelim): 965
length of query: 376
length of database: 18,247,518
effective HSP length: 104
effective length of query: 272
effective length of database: 14,309,454
effective search space: 3892171488
effective search space used: 3892171488
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.