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Search of human proteins with 7019371
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7019371 TCF3 (E2A) fusion partner [Homo sapiens]
(253 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7019371 TCF3 (E2A) fusion partner [Homo sapiens] 509 e-145
gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1 [... 41 0.001
gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo sapi... 40 0.002
gi|122937241 SH3 and multiple ankyrin repeat domains 3 [Homo sap... 40 0.003
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 39 0.004
gi|33356148 formin-like 1 [Homo sapiens] 39 0.004
gi|156071470 hyperpolarization activated cyclic nucleotide-gated... 39 0.006
gi|21361118 DNA-damage-inducible transcript 3 [Homo sapiens] 38 0.007
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 38 0.007
gi|194294554 SET binding protein 1 isoform a [Homo sapiens] 38 0.007
gi|46094079 hepatitis delta antigen-interacting protein A [Homo ... 38 0.007
gi|187960090 SMG5 homolog nonsense mediated mRNA decay factor [H... 38 0.010
gi|109240550 paraspeckle protein 1 [Homo sapiens] 38 0.010
gi|21071077 dishevelled-associated activator of morphogenesis 1 ... 38 0.010
gi|38455396 neurogenin 1 [Homo sapiens] 37 0.013
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 37 0.013
gi|22035606 mitogen-activated protein kinase kinase kinase kinas... 37 0.016
gi|27734727 INO80 complex subunit E [Homo sapiens] 37 0.016
gi|33286446 opioid growth factor receptor [Homo sapiens] 37 0.022
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 37 0.022
gi|169202233 PREDICTED: hypothetical protein [Homo sapiens] 37 0.022
gi|12711674 UPF3 regulator of nonsense transcripts homolog B iso... 37 0.022
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 36 0.028
gi|223972704 hypothetical protein LOC284418 [Homo sapiens] 36 0.028
gi|51944974 tumor suppressor candidate 1 [Homo sapiens] 36 0.028
gi|158854042 hypothetical protein LOC222183 [Homo sapiens] 36 0.028
gi|157266264 pleckstrin homology-like domain, family B, member 3... 36 0.028
gi|195972857 Rho/Rac guanine nucleotide exchange factor 18 isofo... 36 0.037
gi|41327769 Rho/Rac guanine nucleotide exchange factor 18 isofor... 36 0.037
gi|38505268 voltage-dependent calcium channel alpha 1G subunit i... 36 0.037
>gi|7019371 TCF3 (E2A) fusion partner [Homo sapiens]
Length = 253
Score = 509 bits (1312), Expect = e-145
Identities = 253/253 (100%), Positives = 253/253 (100%)
Query: 1 MELEQREGTMAAVGFEEFSAPPGSELALPPLFGGHILESELETEVEFVSGGLGGSGLRER 60
MELEQREGTMAAVGFEEFSAPPGSELALPPLFGGHILESELETEVEFVSGGLGGSGLRER
Sbjct: 1 MELEQREGTMAAVGFEEFSAPPGSELALPPLFGGHILESELETEVEFVSGGLGGSGLRER 60
Query: 61 DEEEEAARGRRRRQRELNRRKYQALGRRCREIEQVNERVLNRLHQVQRITRRLQQERRFL 120
DEEEEAARGRRRRQRELNRRKYQALGRRCREIEQVNERVLNRLHQVQRITRRLQQERRFL
Sbjct: 61 DEEEEAARGRRRRQRELNRRKYQALGRRCREIEQVNERVLNRLHQVQRITRRLQQERRFL 120
Query: 121 MRVLDSYGDDYRASQFTIVLEDEGSQGTDAPTPGNAENEPPEKETLSPPRRTPAPPEPGS 180
MRVLDSYGDDYRASQFTIVLEDEGSQGTDAPTPGNAENEPPEKETLSPPRRTPAPPEPGS
Sbjct: 121 MRVLDSYGDDYRASQFTIVLEDEGSQGTDAPTPGNAENEPPEKETLSPPRRTPAPPEPGS 180
Query: 181 PAPGEGPSGRKRRRVPRDGRRAGNALTPELAPVQIKVEEDFGFEADEALDSSWVSRGPDK 240
PAPGEGPSGRKRRRVPRDGRRAGNALTPELAPVQIKVEEDFGFEADEALDSSWVSRGPDK
Sbjct: 181 PAPGEGPSGRKRRRVPRDGRRAGNALTPELAPVQIKVEEDFGFEADEALDSSWVSRGPDK 240
Query: 241 LLPYPTLASPASD 253
LLPYPTLASPASD
Sbjct: 241 LLPYPTLASPASD 253
>gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1 [Homo
sapiens]
Length = 2564
Score = 40.8 bits (94), Expect = 0.001
Identities = 53/193 (27%), Positives = 72/193 (37%), Gaps = 22/193 (11%)
Query: 61 DEEEEAARGRRRRQRELNRRKYQALGRRCREIEQVNERVLNRLHQVQRITRRLQQERRFL 120
D+ EEAAR RRR +R+ + A EQ+ R R + +R+ R+ E+
Sbjct: 2256 DQSEEAAR-RRRPERQESAEHEAAHSLTLGRYEQMERR---RERRERRLERQESSEQEMP 2311
Query: 121 MRVLDSYGDDYRASQFTIVLEDEGSQGTDA-PTPGNAENEPPEK--ETLSPPRRTPAPPE 177
+R G A + E E G A P+ PP + L P RTP P
Sbjct: 2312 IRGDLVKGKATLADIVEQLQEKEAGPGLPAGPSLPQPRELPPGRLPNGLELPERTPRPDR 2371
Query: 178 PGS---------PAPGEGPSGRKRRRVPRDGRRAGNALTPELAPVQIKVEEDFGFEADE- 227
P + P P EG G RR + G+A P P E F E
Sbjct: 2372 PRARDRPKPRRRPRPREGGEGGGSRRSRSAPAQGGSAPAPPPPPTHTVQHEGFLLRKREL 2431
Query: 228 -----ALDSSWVS 235
+ + SWVS
Sbjct: 2432 DANRKSSNRSWVS 2444
>gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo
sapiens]
Length = 437
Score = 40.0 bits (92), Expect = 0.002
Identities = 39/143 (27%), Positives = 53/143 (37%), Gaps = 26/143 (18%)
Query: 58 RERDEEEEAARGRRRRQRELNRRKYQALGRRCREIEQVNERVLNRLHQVQRITRRLQQER 117
RERD+E E R R R +R +R + + RR RE + +R R R R ++ER
Sbjct: 246 RERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRKRRSSRSRERARRERER 305
Query: 118 RFLMRVLDSYGDDYRASQFTIVLEDEGSQGTDAPTPGNAENEPPEKETLSPPRRTPAPPE 177
+ E+ G D P A + PP+ PP P
Sbjct: 306 K----------------------EELRGGGGDMAEPSEAGDAPPDD---GPPGEL-GPDG 339
Query: 178 PGSPAPGEGPSGRKRRRVPRDGR 200
P P R+RRR R R
Sbjct: 340 PDGPEEKGRDRDRERRRSHRSER 362
>gi|122937241 SH3 and multiple ankyrin repeat domains 3 [Homo
sapiens]
Length = 1747
Score = 39.7 bits (91), Expect = 0.003
Identities = 26/78 (33%), Positives = 37/78 (47%), Gaps = 14/78 (17%)
Query: 127 YGDDYRASQFTIVLEDEGSQGTDAPTPGNAENEPPEKETLSPPRRTPAPPEPGSPAPGEG 186
Y + + ++ I+L+D + DAP P A PPE+ P+R P PP P SP G
Sbjct: 898 YPERQKRARSMIILQDSAPESGDAPRPPPAAT-PPER-----PKRRPRPPGPDSPYANLG 951
Query: 187 --------PSGRKRRRVP 196
PS +RR+ P
Sbjct: 952 AFSASLFAPSKPQRRKSP 969
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 38.9 bits (89), Expect = 0.004
Identities = 40/150 (26%), Positives = 64/150 (42%), Gaps = 22/150 (14%)
Query: 58 RERDEEEEAARGRRRRQRELNRRKYQALGRRCREIEQVNERVLNRLHQVQRITRRLQQER 117
RER+ E E +R R+RE R + + +R RE E+ +ER R QR ++ER
Sbjct: 402 RERERERERENRQRERERERERDRERERRQREREREREHERDKER----QRRKEEWERER 457
Query: 118 RFLMRVLDSYGDDYRASQFTIVLEDEGSQGTDAPTPGNAENEPPEKETLS---------- 167
+ D R + +++G +P P + + EPP+KE +
Sbjct: 458 AKRDEKDRQHRDRDREKERE---KEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADE 514
Query: 168 ---PPRRTPAPPEPGSPAPGEGPSGRKRRR 194
P RR+ +P + PS +RRR
Sbjct: 515 WKDPWRRSKSPKK--KLGVSVSPSRARRRR 542
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 38.9 bits (89), Expect = 0.004
Identities = 40/147 (27%), Positives = 56/147 (38%), Gaps = 14/147 (9%)
Query: 63 EEEAARGRRRRQRELNRRKYQ---ALG--RRCREIEQVNERVLNRLHQVQRITRRLQQER 117
E E + R++ E R ++ A+G RR E E+ R ++ L E
Sbjct: 428 ELEKQLSQARKELETLRERFSESTAMGASRRPPEPEKAPPAAPTRPSALELKVEEL--EE 485
Query: 118 RFLMRVLDSYGDDYRASQFTIVLEDEGSQGTDAPTPGNAENEP-----PEKETLSPPRRT 172
+ L+R+L GD + + G DAPTPG P P E
Sbjct: 486 KGLIRILRGPGDAVSIEILPVAVATPS--GGDAPTPGVPTGSPSPDLAPAAEPAPGAAPP 543
Query: 173 PAPPEPGSPAPGEGPSGRKRRRVPRDG 199
P PP PG P+P E P + P G
Sbjct: 544 PPPPLPGLPSPQEAPPSAPPQAPPLPG 570
Score = 33.5 bits (75), Expect = 0.18
Identities = 18/43 (41%), Positives = 19/43 (44%), Gaps = 6/43 (13%)
Query: 151 PTPGNAENEPPEKETLSPPRRTP------APPEPGSPAPGEGP 187
P PG A PP L P+ P APP PGSP P P
Sbjct: 536 PAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAP 578
Score = 29.3 bits (64), Expect = 3.4
Identities = 14/38 (36%), Positives = 15/38 (39%)
Query: 149 DAPTPGNAENEPPEKETLSPPRRTPAPPEPGSPAPGEG 186
D P P PP + PP P PP PG P G
Sbjct: 583 DLPPPPPPPPPPPGTDGPVPPPPPPPPPPPGGPPDALG 620
Score = 28.9 bits (63), Expect = 4.5
Identities = 18/47 (38%), Positives = 19/47 (40%), Gaps = 7/47 (14%)
Query: 151 PTPGNAENEPPEKETLSPPRRT----PAPPEPGSPAPGEGPSGRKRR 193
P PG+ PP PP T P PP P P PG P RR
Sbjct: 579 PLPGDLPPPPPPPP---PPPGTDGPVPPPPPPPPPPPGGPPDALGRR 622
>gi|156071470 hyperpolarization activated cyclic nucleotide-gated
potassium channel 2 [Homo sapiens]
Length = 889
Score = 38.5 bits (88), Expect = 0.006
Identities = 25/73 (34%), Positives = 34/73 (46%), Gaps = 8/73 (10%)
Query: 140 LEDEGSQGTDAPTPGNAENE-PPEKETLSPPRRTPAPPEPGSPAPGEGPSGRKRRRVPRD 198
++ G G +PG PP +PP++ P PP P +P PG GP+ P+
Sbjct: 1 MDARGGGGRPGESPGATPAPGPPPPPPPAPPQQQPPPPPPPAPPPGPGPA------PPQH 54
Query: 199 GRRAGNALTPELA 211
RA AL PE A
Sbjct: 55 PPRA-EALPPEAA 66
Score = 30.0 bits (66), Expect = 2.0
Identities = 15/45 (33%), Positives = 15/45 (33%)
Query: 168 PPRRTPAPPEPGSPAPGEGPSGRKRRRVPRDGRRAGNALTPELAP 212
PP PA PG P P P R PR G P P
Sbjct: 762 PPGPAPAAASPGPPPPASPPGAPASPRAPRTSPYGGLPAAPLAGP 806
Score = 28.1 bits (61), Expect = 7.7
Identities = 17/44 (38%), Positives = 19/44 (43%), Gaps = 1/44 (2%)
Query: 167 SPPRRTPAPPEPGSPAPGEGPSGRKRRRVPRDGRRAGNALTPEL 210
+P +P PP P SP PG S R R P G A P L
Sbjct: 766 APAAASPGPPPPASP-PGAPASPRAPRTSPYGGLPAAPLAGPAL 808
>gi|21361118 DNA-damage-inducible transcript 3 [Homo sapiens]
Length = 169
Score = 38.1 bits (87), Expect = 0.007
Identities = 22/68 (32%), Positives = 39/68 (57%), Gaps = 8/68 (11%)
Query: 62 EEEEAARGRRRRQRELNRRKYQALGRRCREIEQVNERVLNRL--------HQVQRITRRL 113
EEEE +GR R++++ +A +R +E EQ NER + +L +++R+TR +
Sbjct: 93 EEEEEDQGRTRKRKQSGHSPARAGKQRMKEKEQENERKVAQLAEENERLKQEIERLTREV 152
Query: 114 QQERRFLM 121
+ RR L+
Sbjct: 153 EATRRALI 160
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 38.1 bits (87), Expect = 0.007
Identities = 34/112 (30%), Positives = 53/112 (47%), Gaps = 21/112 (18%)
Query: 57 LRERDEEEEAARGRRRRQRELNRRKYQALGRRCREIEQVNERVLNRLHQVQRITRRLQQE 116
L+ER+E E A R +R + R+YQ R +++E+V + R +++ RR ++E
Sbjct: 823 LKEREERERAERAKREEEL----REYQ---ERVKKLEEVERKKRQRELEIEERERRREEE 875
Query: 117 RRFLMRVLDSYGDDYRASQFTIVLEDEGSQGTDAPTPGNAENE----PPEKE 164
RR D S+ D S+GT P A++E PPEKE
Sbjct: 876 RRL---------GDSSLSRKDSRWGDRDSEGTWRKGP-EADSEWRRGPPEKE 917
>gi|194294554 SET binding protein 1 isoform a [Homo sapiens]
Length = 1596
Score = 38.1 bits (87), Expect = 0.007
Identities = 41/160 (25%), Positives = 61/160 (38%), Gaps = 10/160 (6%)
Query: 90 REIEQVNERVLNRLHQVQRITRRLQQERRFLMRVLDSYGD-----DYRASQFTIVLEDEG 144
R+ + N V R + ++ + ++ R M VL+ D + S +VLE
Sbjct: 1441 RQSKTGNNFVKKRRGRPRKQPTQFDEDSRDQMPVLEKCIDLPSKRGQKPSLSPLVLEPAA 1500
Query: 145 SQGTDAPTPGNAENEPPEKETLSPPRRTPAPPEPGSPAPGEGPSGRKRRRVPRDGRRAGN 204
SQ T T + E L PP P PP P P P P + PR G+R
Sbjct: 1501 SQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPPPPLPPPPP----LPKTPRGGKRKHK 1556
Query: 205 ALTPELAPVQIKVEEDFGFEADEALDSSWVSRGPD-KLLP 243
P P Q ++ E + SRG + ++LP
Sbjct: 1557 PQAPAQPPQQSPPQQPLPQEEEVKAKRQRKSRGSESEVLP 1596
>gi|46094079 hepatitis delta antigen-interacting protein A [Homo
sapiens]
Length = 202
Score = 38.1 bits (87), Expect = 0.007
Identities = 25/71 (35%), Positives = 40/71 (56%), Gaps = 6/71 (8%)
Query: 56 GLRERDEEEEAARGRRRRQRELNRR---KYQALGRRCREIEQVNERV---LNRLHQVQRI 109
GL E +EE AA G+ R L R + AL +R R +++VN ++ L + +++++
Sbjct: 7 GLEELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEIRELKQL 66
Query: 110 TRRLQQERRFL 120
RRLQ E R L
Sbjct: 67 NRRLQAENREL 77
Score = 29.6 bits (65), Expect = 2.6
Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 6/83 (7%)
Query: 41 LETEVEFVSGGLGGSGLRERDEEEEAAR-----GRRRRQRELNRRKYQALGRRCREIEQV 95
LE + LG L R EEAAR R R +E+NR+ LG RE++Q+
Sbjct: 8 LEELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGE-IRELKQL 66
Query: 96 NERVLNRLHQVQRITRRLQQERR 118
N R+ +++ + L ER+
Sbjct: 67 NRRLQAENRELRDLCCFLDSERQ 89
>gi|187960090 SMG5 homolog nonsense mediated mRNA decay factor [Homo
sapiens]
Length = 1016
Score = 37.7 bits (86), Expect = 0.010
Identities = 32/97 (32%), Positives = 41/97 (42%), Gaps = 19/97 (19%)
Query: 145 SQGTDAPTPGNAENEPPEKETLSPPRRTPAPPEPGSPAPGEGPSGRKRRRVPRDGRRAGN 204
S GTD P EP EKE P P P +P GEG RK R+ +
Sbjct: 415 SDGTDEPE----SKEPVEKEEEPDPE-----PPPVTPQVGEGRKSRKFSRL--------S 457
Query: 205 ALTPELAPVQIKVEEDF--GFEADEALDSSWVSRGPD 239
L P ++ + D GFE+D + DS+ S G D
Sbjct: 458 CLRRRRHPPKVGDDSDLSEGFESDSSHDSARASEGSD 494
>gi|109240550 paraspeckle protein 1 [Homo sapiens]
Length = 523
Score = 37.7 bits (86), Expect = 0.010
Identities = 43/181 (23%), Positives = 72/181 (39%), Gaps = 24/181 (13%)
Query: 57 LRERDEEEEAARGRRRRQRELNRRKYQALGRR--CREIEQVNERVLNRLHQVQ------- 107
+RE E+ EA R + +L + + R+ R +E++ + L + Q+Q
Sbjct: 297 IREAKEKLEAEMEAARHEHQLMLMRQDLMRRQEELRRLEELRNQELQKRKQIQLRHEEEH 356
Query: 108 -----RITRRLQQERRFLMRVLDSYGDDYRAS-QFTIVLEDEGSQGT----DAPTPGNAE 157
+ R +QE L R + + +Y + + + + D G +G DA +P A
Sbjct: 357 RRREEEMIRHREQEE--LRRQQEGFKPNYMENREQEMRMGDMGPRGAINMGDAFSPAPAG 414
Query: 158 NE-PPEKETLSPPRRTPAPPEPGSPAPGEGPSGRKRRRVPR--DGRRAGNALTPELAPVQ 214
N+ PP ++ R P P P P GP G P D N P+ P Q
Sbjct: 415 NQGPPPMMGMNMNNRATIPGPPMGPGPAMGPEGAANMGTPMMPDNGAVHNDRFPQGPPSQ 474
Query: 215 I 215
+
Sbjct: 475 M 475
>gi|21071077 dishevelled-associated activator of morphogenesis 1
[Homo sapiens]
Length = 1078
Score = 37.7 bits (86), Expect = 0.010
Identities = 38/171 (22%), Positives = 65/171 (38%), Gaps = 15/171 (8%)
Query: 64 EEAARGRRRRQRELNRRKYQALGRRCREIEQVNERVLNRLHQV-QRITRRLQQERRFLMR 122
+E A R+ EL ++K + R C Q E ++ L+++ +++ + + ++ +
Sbjct: 449 KEQAEKMRKEHNEL-QQKLEKKERECDAKTQEKEEMMQTLNKMKEKLEKETTEHKQVKQQ 507
Query: 123 VLDSYGDDYRASQFTIVLEDEGSQGTDAP-------TPGNAENEPPEKET---LSPPRRT 172
V D + S+ + G AP PG+ PP + PP
Sbjct: 508 VADLTAQLHELSRRAVCASIPGGPSPGAPGGPFPSSVPGSLLPPPPPPPLPGGMLPPPPP 567
Query: 173 PAPPEPGSPAPGEGPSGRKRRRVPRDGRRAGNALTPELAPVQIKVEEDFGF 223
P PP P PG P G +P G G AL + P + F +
Sbjct: 568 PLPPGGPPPPPGPPPLG---AIMPPPGAPMGLALKKKSIPQPTNALKSFNW 615
>gi|38455396 neurogenin 1 [Homo sapiens]
Length = 237
Score = 37.4 bits (85), Expect = 0.013
Identities = 39/140 (27%), Positives = 58/140 (41%), Gaps = 41/140 (29%)
Query: 60 RDEEEEAARGRRRRQRELNRRKYQALGRRCREIEQV--NERVLNRLHQVQRITRRLQQER 117
+D+E+E RRR+R R + +AL R +V N+R NR+H + L+
Sbjct: 65 QDDEQE-----RRRRRGRTRVRSEALLHSLRRSRRVKANDRERNRMHNLNAALDALRS-- 117
Query: 118 RFLMRVLDSYGDDYRASQF---------------TIVLEDEGSQGTDAPTPGNAENEPPE 162
VL S+ DD + ++ T+ L D+G G A
Sbjct: 118 -----VLPSFPDDTKLTKIETLRFAYNYIWALAETLRLADQGLPGGGA------------ 160
Query: 163 KETLSPPRRTPAPPEPGSPA 182
+E L PP+ P P P SPA
Sbjct: 161 RERLLPPQCVPCLPGPPSPA 180
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 37.4 bits (85), Expect = 0.013
Identities = 40/158 (25%), Positives = 62/158 (39%), Gaps = 28/158 (17%)
Query: 58 RERDEEEEAARGR---------RRRQRELNRRKYQALGRRCREIEQVNERVLNRLHQVQR 108
RER+ E+E R R R R+RE +R K + R RE E+ ER R + +R
Sbjct: 715 REREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERER 774
Query: 109 ITRRLQQERRFLMRVLD--SYGDDYRASQFTIVLEDEGSQGTDAPTPGNAENEPPEKETL 166
R + + R R + G D R + + ED P G+ E + ++
Sbjct: 775 ERARERDKERERQRDWEDKDKGRDDRREKREEIREDRN------PRDGHDERKSKKRYR- 827
Query: 167 SPPRRTPAPPEPGSPAPGEGPSGRKRRRVPRDGRRAGN 204
GSP+P + P R+ D +G+
Sbjct: 828 ----------NEGSPSPRQSPKRRREHSPDSDAYNSGD 855
Score = 31.2 bits (69), Expect = 0.91
Identities = 24/65 (36%), Positives = 32/65 (49%), Gaps = 4/65 (6%)
Query: 58 RERDEEEEAARGR---RRRQRELNRRKYQALGR-RCREIEQVNERVLNRLHQVQRITRRL 113
RERD E E R R R R+R+ R K + L R R RE E+ E+ +R R R
Sbjct: 677 RERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRE 736
Query: 114 QQERR 118
++ R
Sbjct: 737 RERER 741
>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
isoform 3 [Homo sapiens]
Length = 1212
Score = 37.0 bits (84), Expect = 0.016
Identities = 38/160 (23%), Positives = 65/160 (40%), Gaps = 7/160 (4%)
Query: 57 LRERDEEEEAARGRRRRQRELNRRKYQALGRRCREIEQVNERVLNRLHQVQR------IT 110
L ER + E + +RRR E RR+ +A ++ RE + + RL +++R
Sbjct: 392 LAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEER 451
Query: 111 RRLQQERRFLMRVLDSYGDDYRASQFTI-VLEDEGSQGTDAPTPGNAENEPPEKETLSPP 169
RR ++E+R + R + Q + VL+ + Q + P + PP
Sbjct: 452 RRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLHDHRRPHPQHSQQPPPP 511
Query: 170 RRTPAPPEPGSPAPGEGPSGRKRRRVPRDGRRAGNALTPE 209
++ + P +P P R R D R N +PE
Sbjct: 512 QQERSKPSFHAPEPKAHYEPADRAREVEDRFRKTNHSSPE 551
>gi|27734727 INO80 complex subunit E [Homo sapiens]
Length = 244
Score = 37.0 bits (84), Expect = 0.016
Identities = 29/107 (27%), Positives = 52/107 (48%), Gaps = 13/107 (12%)
Query: 79 RRKYQALGRRCREIEQVNERVLNRLHQVQRITRRLQQERRFLMRVLDSYGDDYRASQFTI 138
++KY+ L R+ + + +E L + QR ++ +++ FL+ L Y +
Sbjct: 12 KKKYRNLKRKLKFLIYEHECFQEELRKAQRKLLKVSRDKSFLLDRLLQYEN--------- 62
Query: 139 VLEDEGSQGTDAPTPG-NAENEPPEKETLSP-PRRTPAPPEPGSPAP 183
DE S +DA N+E E K + +P P+R +PP G+P+P
Sbjct: 63 --VDEDSSDSDATASSDNSETEGTPKLSDTPAPKRKRSPPLGGAPSP 107
>gi|33286446 opioid growth factor receptor [Homo sapiens]
Length = 677
Score = 36.6 bits (83), Expect = 0.022
Identities = 28/96 (29%), Positives = 37/96 (38%), Gaps = 3/96 (3%)
Query: 143 EGSQGTDAPTPGNAENEPPEKETLSPPRRTPAPPEPGSPAPGEGPSGRKRRRVPRDGRRA 202
EG+ G+ + TPG + P E P TP P P PA E PR A
Sbjct: 512 EGTPGSPSETPGPSPAGPAGDEPAESPSETPG-PRPAGPAGDEPAESPSETPGPRPAGPA 570
Query: 203 GNALTPELAPVQIKVEEDFGFEADEALDSSWVSRGP 238
G+ P +P + G DE +S + GP
Sbjct: 571 GD--EPAESPSETPGPSPAGPTRDEPAESPSETPGP 604
Score = 28.5 bits (62), Expect = 5.9
Identities = 18/50 (36%), Positives = 22/50 (44%), Gaps = 6/50 (12%)
Query: 144 GSQGTDAP--TPGNAENEPPEKETLSPPRRTPAPPEPGSPA---PGEGPS 188
G + ++P TPG + P E P TP P P PA P E PS
Sbjct: 571 GDEPAESPSETPGPSPAGPTRDEPAESPSETPG-PRPAGPAGDEPAESPS 619
Score = 28.5 bits (62), Expect = 5.9
Identities = 23/67 (34%), Positives = 28/67 (41%), Gaps = 8/67 (11%)
Query: 143 EGSQGTDAPTP-GNAENEPPEKETLSPPRRTPAPPEPGSPA------PGEGPSGRKRRRV 195
E T P P G A +EP E + +P R PA P PA PG P+G R
Sbjct: 596 ESPSETPGPRPAGPAGDEPAESPSETPGPR-PAGPAGDEPAESPSETPGPSPAGPTRDEP 654
Query: 196 PRDGRRA 202
+ G A
Sbjct: 655 AKAGEAA 661
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 36.6 bits (83), Expect = 0.022
Identities = 39/141 (27%), Positives = 57/141 (40%), Gaps = 5/141 (3%)
Query: 58 RERDEEEEAARGRRRR---QRELNRRKYQALGRRCREIEQVNERVLNRLHQVQRITRRLQ 114
RER+ E E RGR R+ QRE R++ A R R+ ++ +R R Q +R + +
Sbjct: 127 RERETEREGERGRDRQTDGQRERERQR-DAEKERERQTDRERQRQTERNRQKEREREKNR 185
Query: 115 QERRFLMRVLDSYG-DDYRASQFTIVLEDEGSQGTDAPTPGNAENEPPEKETLSPPRRTP 173
QERR R + + R S+ E E T+ + E + R
Sbjct: 186 QERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQ 245
Query: 174 APPEPGSPAPGEGPSGRKRRR 194
A E S E R+R R
Sbjct: 246 AERERASERETERDKERERER 266
Score = 35.8 bits (81), Expect = 0.037
Identities = 23/64 (35%), Positives = 33/64 (51%), Gaps = 3/64 (4%)
Query: 58 RERDEEEEAARGRRRRQRELNR---RKYQALGRRCREIEQVNERVLNRLHQVQRITRRLQ 114
+ER+ E + R R RRQ+E R RK Q R RE E+ ER R + +R +R +
Sbjct: 260 KERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRER 319
Query: 115 QERR 118
+ R
Sbjct: 320 ERER 323
Score = 34.3 bits (77), Expect = 0.11
Identities = 32/104 (30%), Positives = 48/104 (46%), Gaps = 9/104 (8%)
Query: 58 RERDEEEEAARGRRRRQ--RELNRRKYQALGRRCREIEQVNERVLNRLHQVQRITRRLQQ 115
RER+ ++E R R +RQ RE +R++ R RE ++ +R +R Q R R +Q
Sbjct: 54 RERNRQKERERRREKRQTERETDRKR-----ERRREKDRHRKRDRHRERQRDREKERERQ 108
Query: 116 ERRFLMRVLDSYGDDYRASQFTIVLEDEGSQGTDAPTPGNAENE 159
R R + + R + E EG +G D T G E E
Sbjct: 109 TDRERDRQREK--ERNRQKERERETEREGERGRDRQTDGQRERE 150
Score = 32.3 bits (72), Expect = 0.41
Identities = 21/60 (35%), Positives = 33/60 (55%), Gaps = 2/60 (3%)
Query: 59 ERDEEEEAARGRRRRQRELNRRKYQALGRR-CREIEQVNERVLNRLHQVQRITRRLQQER 117
ERD E+E R +R+RQ E++R + + GR R+ E+ ER R Q R +++R
Sbjct: 334 ERDREKERER-KRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDR 392
Score = 31.2 bits (69), Expect = 0.91
Identities = 22/60 (36%), Positives = 33/60 (55%), Gaps = 6/60 (10%)
Query: 59 ERDEEEEAARGRRR---RQRELNRRKYQALGRRCREIEQVNERVLNRLHQVQRITRRLQQ 115
ERD E E R R+R R+RE NR++ + R RE E+ +R R + +R +R +Q
Sbjct: 292 ERDRETERKRERQRERERERERNRKRER---ERERERERERQRETERDREKERERKRKRQ 348
Score = 29.6 bits (65), Expect = 2.6
Identities = 30/89 (33%), Positives = 40/89 (44%), Gaps = 8/89 (8%)
Query: 38 ESELETEVEFVSGGLGGSGLRERDEEEEAARGR-----RRRQRELNR-RKYQALGRRC-- 89
+ E E + E G RER+ E E R R R RQR+ R R+ QA R
Sbjct: 194 QREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASE 253
Query: 90 REIEQVNERVLNRLHQVQRITRRLQQERR 118
RE E+ ER R R R+ ++ER+
Sbjct: 254 RETERDKERERERDRDRDRDRRQKERERQ 282
Score = 29.6 bits (65), Expect = 2.6
Identities = 40/166 (24%), Positives = 67/166 (40%), Gaps = 26/166 (15%)
Query: 58 RERDEEEEAARGRRRRQRELNRRKYQALGRRC-------REIEQVNERVLNRLHQVQRIT 110
RER+ + ++AR R R+R+ +R + + R+ RE E+ ER +R + R
Sbjct: 373 RERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRER 432
Query: 111 RRLQQERRFLMRVLDSYGDDYRASQFTIVLEDEGSQGTDAPTPGNAENEPPEKETLSPPR 170
R +++++ R D R + + + S P P A + + + P R
Sbjct: 433 GREREKQKGRER------DRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTR 486
Query: 171 --RTPAPPEPGSPAPGEGPSGR-----------KRRRVPRDGRRAG 203
R + PE A P GR +RR PR G + G
Sbjct: 487 GIRWKSSPEDPKAASTRFPWGRPAKASRGRVAGRRRWEPRLGEKRG 532
Score = 28.5 bits (62), Expect = 5.9
Identities = 24/73 (32%), Positives = 34/73 (46%), Gaps = 10/73 (13%)
Query: 58 RERDEEEEAARGR-----RRRQRELNRRKYQALGRRCREIEQVNERVLNRLHQVQRITRR 112
R+RD E+E R R+R++E NR+K R RE E+ ER +R QR R
Sbjct: 97 RQRDREKERERQTDRERDRQREKERNRQK-----ERERETEREGERGRDRQTDGQRERER 151
Query: 113 LQQERRFLMRVLD 125
+ + R D
Sbjct: 152 QRDAEKERERQTD 164
>gi|169202233 PREDICTED: hypothetical protein [Homo sapiens]
Length = 381
Score = 36.6 bits (83), Expect = 0.022
Identities = 34/123 (27%), Positives = 48/123 (39%), Gaps = 9/123 (7%)
Query: 90 REIEQVNERVLNRLHQVQRITRRLQQERRFLMRVLDSYGDDYRASQFTIVLEDEGSQGTD 149
R++EQ+ R HQ +R ++L + + L RA+ T + D
Sbjct: 241 RQVEQLQHR-----HQHERGQQQLVEGAPDGVGHLHGSRGSGRAATTTRPQTTPAAASPD 295
Query: 150 APTPGN-AENEPPEKETLSPPRRTPA---PPEPGSPAPGEGPSGRKRRRVPRDGRRAGNA 205
P P + EP E +PPR PA PP +P+P S R PR R A
Sbjct: 296 LPQPAERSRGEPRPAEPRAPPRPPPAARRPPPATAPSPRRAGSPPTREEEPRPRRSAARP 355
Query: 206 LTP 208
P
Sbjct: 356 QCP 358
>gi|12711674 UPF3 regulator of nonsense transcripts homolog B
isoform 2 [Homo sapiens]
Length = 470
Score = 36.6 bits (83), Expect = 0.022
Identities = 41/167 (24%), Positives = 72/167 (43%), Gaps = 21/167 (12%)
Query: 58 RERDEEEEAARGR---RRRQRELNRRKYQALGRRCREIEQVNERVLNRLHQVQRITRR-- 112
R R+E+ E R R R+RQRE RRK+ +E E+ + + +L ++ RI R
Sbjct: 209 RMREEKREERRRREIERKRQREEERRKW-------KEEEKRKRKDIEKLKKIDRIPERDK 261
Query: 113 LQQERRFLMRVLDSYGDDYRASQFTIVLEDEGSQGTDAPTPGNAENEPPEKETLSPPRRT 172
L+ E + + GD+ + E ++ D N +E ++ + P+R+
Sbjct: 262 LKDEPKIKLLKKPEKGDEKELD------KREKAKKLDKE---NLSDERASGQSCTLPKRS 312
Query: 173 PAPPEPGSPAPGEGPSGRKRRRVPRDGRRAGNALTPELAPVQIKVEE 219
+ + P E SGR R R+ R + E ++ + EE
Sbjct: 313 DSELKDEKPKRPEDESGRDYREREREYERDQERILRERERLKRQEEE 359
Score = 32.3 bits (72), Expect = 0.41
Identities = 34/143 (23%), Positives = 60/143 (41%), Gaps = 16/143 (11%)
Query: 63 EEEAARGRRRRQRELNRRKYQALGRRCREIEQVNERVLNRLHQVQRITRRLQQERRFLMR 122
E+E+ R R R+RE R + + L R R Q ER +R R ++E+ F +
Sbjct: 325 EDESGRDYREREREYERDQERILRERERLKRQEEER--------RRQKERYEKEKTFKRK 376
Query: 123 VLDSYGDDYRASQFTIVLEDEGSQGTDAPTPGNAENEPPEKETLSPPRRTPAPPEPGSPA 182
++ + + T L D+G + + G++E + +KE + R P
Sbjct: 377 -----EEEMKKEKDT--LRDKGKKAESTESIGSSE-KTEKKEEVVKRDRIRNKDRPAMQL 428
Query: 183 PGEGPSGRKRRRVPRDGRRAGNA 205
G R R P D ++G++
Sbjct: 429 YQPGARSRNRLCPPDDSTKSGDS 451
Score = 28.9 bits (63), Expect = 4.5
Identities = 36/157 (22%), Positives = 57/157 (36%), Gaps = 10/157 (6%)
Query: 38 ESELETEVEFVSGGLGGSGLRERDEEEEAARGRRRRQRELNRRKYQALGRRCREIEQVNE 97
+SEL+ E G RER+ E E R + R RE R K Q RR ++ E
Sbjct: 313 DSELKDEKPKRPEDESGRDYREREREYE--RDQERILRERERLKRQEEERRRQKERYEKE 370
Query: 98 RVLNRLHQVQRITRRLQQERRFLMRVLDSYGDDYRASQFTIVLEDEGSQGTDAPT----- 152
+ R + + + +++ +S G + + V++ + + D P
Sbjct: 371 KTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEVVKRDRIRNKDRPAMQLYQ 430
Query: 153 PGNAENE---PPEKETLSPPRRTPAPPEPGSPAPGEG 186
PG PP+ T S E G EG
Sbjct: 431 PGARSRNRLCPPDDSTKSGDSAAERKQESGISHRKEG 467
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 36.2 bits (82), Expect = 0.028
Identities = 40/169 (23%), Positives = 69/169 (40%), Gaps = 35/169 (20%)
Query: 57 LRERDEEEEAARGRRRRQRELNRRKYQALGRRCREIEQVNERVLNRLH-----QVQRITR 111
LR+R++E EA R+R++E E+E++ +R+L H ++QR+ +
Sbjct: 522 LRDREKEMEADERDRKREKE--------------ELEEIRQRLLAEGHPDPDAELQRMEQ 567
Query: 112 RLQQERRFLMRVLDSYGDDYRASQFTIVLEDEGSQGTDAPTPGNAENEPPEKETLSPPRR 171
++ R+ ++ ++ E++ + P E EP +K L P R
Sbjct: 568 EAERRRQPQIKQEPESEEEE---------EEKQEKEEKREEPMEEEEEPEQKPCLKPTLR 618
Query: 172 TPAPPEPGSPAPG-EGPSGRKRRRVPRDGRRAGNALTPELAPVQIKVEE 219
P S AP SG P D G + E +P Q + EE
Sbjct: 619 ------PISSAPSVSSASGNATPNTPGDESPCGIIIPHENSPDQQQPEE 661
Score = 31.6 bits (70), Expect = 0.69
Identities = 36/159 (22%), Positives = 59/159 (37%), Gaps = 1/159 (0%)
Query: 58 RERDEEEEAARGRRRRQRELNRRKYQALGRRCREIEQVNERVLNRLHQVQRITRRLQQER 117
RER+ E E R RR R+RE R + + + RE E+ +R +R + R R +
Sbjct: 310 RERERERERERERREREREREREREREKEKE-RERERERDRDRDRTKERDRDRDRERDRD 368
Query: 118 RFLMRVLDSYGDDYRASQFTIVLEDEGSQGTDAPTPGNAENEPPEKETLSPPRRTPAPPE 177
R R D D R+ + + E E + + E E + R +
Sbjct: 369 RDRERSSDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKD 428
Query: 178 PGSPAPGEGPSGRKRRRVPRDGRRAGNALTPELAPVQIK 216
+ +RR++ R R A L +I+
Sbjct: 429 KKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIR 467
Score = 29.3 bits (64), Expect = 3.4
Identities = 28/82 (34%), Positives = 38/82 (46%), Gaps = 3/82 (3%)
Query: 54 GSGLRERDEEEEAARGRRR-RQRELNRRKYQALGRRCREIEQVNERVLNRLHQVQRITRR 112
G +ER E E+ R R R R+RE RR+ + R RE E+ ER R + R R
Sbjct: 296 GKKEKERQEIEKERRERERERERERERREREREREREREREKEKER--ERERERDRDRDR 353
Query: 113 LQQERRFLMRVLDSYGDDYRAS 134
++ R R D D R+S
Sbjct: 354 TKERDRDRDRERDRDRDRERSS 375
Score = 28.9 bits (63), Expect = 4.5
Identities = 33/151 (21%), Positives = 58/151 (38%), Gaps = 19/151 (12%)
Query: 58 RERDEEEEAARGRRRRQRELNRRKYQALGRRCREIEQVNERVLNRLHQ-----VQRITRR 112
++RD EE+ RR+ E R+ +A + + ++ ER R ++ + R
Sbjct: 429 KKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRRE 488
Query: 113 LQQERRFLMRVLDSYGDD------YRASQFTIVLEDEGSQGTDAPTPGNAENEPPEKETL 166
+ +E + L L+ Y DD YR S L D + + + EKE L
Sbjct: 489 MAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDR-----EKEMEADERDRKREKEEL 543
Query: 167 SPPRR---TPAPPEPGSPAPGEGPSGRKRRR 194
R+ P+P + +RR+
Sbjct: 544 EEIRQRLLAEGHPDPDAELQRMEQEAERRRQ 574
>gi|223972704 hypothetical protein LOC284418 [Homo sapiens]
Length = 922
Score = 36.2 bits (82), Expect = 0.028
Identities = 21/57 (36%), Positives = 27/57 (47%), Gaps = 5/57 (8%)
Query: 151 PTPGNAENEPPEKETLS--PPRRTPAPPEPGSPAPGEGPSGRKRRRVPRDGRRAGNA 205
P PG A PP+K + PPR+ PA P P AP +K +P R+A A
Sbjct: 432 PPPGLA---PPQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKAPAIPAPSRKASAA 485
Score = 28.5 bits (62), Expect = 5.9
Identities = 18/64 (28%), Positives = 23/64 (35%), Gaps = 2/64 (3%)
Query: 147 GTDAPTPGNAENEPPEKETL--SPPRRTPAPPEPGSPAPGEGPSGRKRRRVPRDGRRAGN 204
G P A + PP K +P ++ PA P P AP RK R+A
Sbjct: 435 GLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKAPAIPAPSRKASAASASPRKASA 494
Query: 205 ALTP 208
P
Sbjct: 495 VPAP 498
>gi|51944974 tumor suppressor candidate 1 [Homo sapiens]
Length = 212
Score = 36.2 bits (82), Expect = 0.028
Identities = 39/133 (29%), Positives = 54/133 (40%), Gaps = 20/133 (15%)
Query: 49 SGGLGGSGLRERDEEEEAARGRRRRQRELNRRKYQALGRRCREIEQVNERVLNRLHQVQR 108
SGG GG G R R + A + R +L +A+ R E ++ N R+ +++
Sbjct: 42 SGGGGGVGWRGR--ADGARQQLEERFADLAASHLEAIRAR-DEWDRQNARLRQENARLRL 98
Query: 109 ITRRLQQERRFLMRVLDSYGDDYRASQFTIVLEDEGSQGTDAPTPGNAENEPPEKETLSP 168
RRL++E R L R + L EG GT P A P E T
Sbjct: 99 ENRRLKRENRSLFRQ-------------ALRLPGEGGNGT----PAEARRVPEEASTNRR 141
Query: 169 PRRTPAPPEPGSP 181
R + EPGSP
Sbjct: 142 ARDSGREDEPGSP 154
>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
Length = 653
Score = 36.2 bits (82), Expect = 0.028
Identities = 49/229 (21%), Positives = 77/229 (33%), Gaps = 54/229 (23%)
Query: 33 GGHILESELETEVEFVSGGLGGSGLRERDEEEEAARGRRRRQRELNRRKYQALGRRCREI 92
GGH S + +E S LR++ + + R R +R++++ +C+
Sbjct: 176 GGH-RRSRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRK 234
Query: 93 EQVNERVLNRLHQVQRITRRLQQERRFLMRVLDSYGDDYRASQFTIVLEDEG-------S 145
E+ E+ R + R + Y D S+ + DEG S
Sbjct: 235 EKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRS 294
Query: 146 QGTDAPTPGNAE-------------------------NEPPEKETLSPPR-------RTP 173
G+ +P+P + PP+K + PR P
Sbjct: 295 SGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAP 354
Query: 174 APPEPG--SPAPGEGPS------------GRKRRRVPRDGRRAGNALTP 208
PP G SP+P PS GR+RRR R R +A P
Sbjct: 355 TPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAP 403
>gi|157266264 pleckstrin homology-like domain, family B, member 3
[Homo sapiens]
Length = 640
Score = 36.2 bits (82), Expect = 0.028
Identities = 35/138 (25%), Positives = 56/138 (40%), Gaps = 10/138 (7%)
Query: 37 LESELETEVEFVSGGLGGSGLRERDEEEE---------AARGRRRRQRELNRRKYQALGR 87
L E+E EV + G L G + R EEE+ A+ R R+QRE +R+
Sbjct: 129 LRIEMEVEVALLRGELAGERVAARREEEQLRELLEQQAASEQRGRQQREQEQRRLSQERD 188
Query: 88 RCREIEQVNERVLNRL-HQVQRITRRLQQERRFLMRVLDSYGDDYRASQFTIVLEDEGSQ 146
R + Q + +L Q + RL Q + + LD Y +F + + +
Sbjct: 189 RLEGLRQRLRKAQGQLDSQPEDQRERLLQGVQEMREQLDVAQRAYEDLEFQQLERESRQE 248
Query: 147 GTDAPTPGNAENEPPEKE 164
D +PG +P +E
Sbjct: 249 EEDRDSPGPQVPDPKVQE 266
>gi|195972857 Rho/Rac guanine nucleotide exchange factor 18 isoform b
[Homo sapiens]
Length = 1173
Score = 35.8 bits (81), Expect = 0.037
Identities = 42/172 (24%), Positives = 71/172 (41%), Gaps = 15/172 (8%)
Query: 59 ERDEEEEAARGRRRRQRELNRRKYQALGR-RCREIEQVNERVLNRLHQVQRITRRLQQER 117
E+ EE AA + + Q +++++ + + +E+E+ R+ R + +++ RL+QER
Sbjct: 859 EKQREERAALEKLQSQLRHEQQRWERERQWQHQELERAGARLQEREGEARQLRERLEQER 918
Query: 118 RFLMRVLDSYGDD---YRASQFTIVLEDEGSQGTDAPTPGNAENEPPEKETLS---PPRR 171
L R +Y D R +Q + E E + N +TL+ PP
Sbjct: 919 AELERQRQAYQHDLERLREAQRAVERERERLELLRRLKKQNTAPGALPPDTLAEAQPPSH 978
Query: 172 TPAPPEPGSPAP-------GEGPSGRKRRRVP-RDGRRAGNALTPELAPVQI 215
P+ G P G GP +R V RD N L P+Q+
Sbjct: 979 PPSFNGEGLEGPRVSMLPSGVGPEYAERPEVARRDSAPTENRLAKSDVPIQL 1030
Score = 30.8 bits (68), Expect = 1.2
Identities = 23/66 (34%), Positives = 30/66 (45%), Gaps = 13/66 (19%)
Query: 147 GTDAPTPGNAENEPPEKETLSPPRRTPAPP-EPGSPAPGEGPSGRKRRRVPRDG---RRA 202
G D T N + P + P R +PAPP +PG PAP P+ P +G +
Sbjct: 1090 GKDESTSRNRRSLSP----ILPGRHSPAPPPDPGFPAPSPPPADS-----PSEGFSLKAG 1140
Query: 203 GNALTP 208
G AL P
Sbjct: 1141 GTALLP 1146
>gi|41327769 Rho/Rac guanine nucleotide exchange factor 18 isoform a
[Homo sapiens]
Length = 1015
Score = 35.8 bits (81), Expect = 0.037
Identities = 42/172 (24%), Positives = 71/172 (41%), Gaps = 15/172 (8%)
Query: 59 ERDEEEEAARGRRRRQRELNRRKYQALGR-RCREIEQVNERVLNRLHQVQRITRRLQQER 117
E+ EE AA + + Q +++++ + + +E+E+ R+ R + +++ RL+QER
Sbjct: 701 EKQREERAALEKLQSQLRHEQQRWERERQWQHQELERAGARLQEREGEARQLRERLEQER 760
Query: 118 RFLMRVLDSYGDD---YRASQFTIVLEDEGSQGTDAPTPGNAENEPPEKETLS---PPRR 171
L R +Y D R +Q + E E + N +TL+ PP
Sbjct: 761 AELERQRQAYQHDLERLREAQRAVERERERLELLRRLKKQNTAPGALPPDTLAEAQPPSH 820
Query: 172 TPAPPEPGSPAP-------GEGPSGRKRRRVP-RDGRRAGNALTPELAPVQI 215
P+ G P G GP +R V RD N L P+Q+
Sbjct: 821 PPSFNGEGLEGPRVSMLPSGVGPEYAERPEVARRDSAPTENRLAKSDVPIQL 872
Score = 30.8 bits (68), Expect = 1.2
Identities = 23/66 (34%), Positives = 30/66 (45%), Gaps = 13/66 (19%)
Query: 147 GTDAPTPGNAENEPPEKETLSPPRRTPAPP-EPGSPAPGEGPSGRKRRRVPRDG---RRA 202
G D T N + P + P R +PAPP +PG PAP P+ P +G +
Sbjct: 932 GKDESTSRNRRSLSP----ILPGRHSPAPPPDPGFPAPSPPPADS-----PSEGFSLKAG 982
Query: 203 GNALTP 208
G AL P
Sbjct: 983 GTALLP 988
>gi|38505268 voltage-dependent calcium channel alpha 1G subunit
isoform 14 [Homo sapiens]
Length = 2171
Score = 35.8 bits (81), Expect = 0.037
Identities = 38/136 (27%), Positives = 49/136 (36%), Gaps = 18/136 (13%)
Query: 70 RRRRQRELNRRKYQALGRR---CREIEQVNERVLNRLHQVQRITRRLQQERRFLMRVLDS 126
RR+ + Q LG R E E + R L + + V E + R S
Sbjct: 2004 RRQAAIRTDSLDVQGLGSREDLLAEEEPPSPRDLKKCYSV---------EAQSCQRRPTS 2054
Query: 127 YGDDYRASQFTIVLEDEGSQGTDAPTPGNAENEP------PEKETLSPPRRTPAPPEPGS 180
+ D+ R + D GSQ P N +P K+ LSPP T PPE
Sbjct: 2055 WLDEQRRHSIAVSCLDSGSQPHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQG 2114
Query: 181 PAPGEGPSGRKRRRVP 196
P P RRR P
Sbjct: 2115 PRTPPSPGICLRRRAP 2130
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.134 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,709,297
Number of Sequences: 37866
Number of extensions: 794269
Number of successful extensions: 11247
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 248
Number of HSP's successfully gapped in prelim test: 596
Number of HSP's that attempted gapping in prelim test: 8169
Number of HSP's gapped (non-prelim): 3216
length of query: 253
length of database: 18,247,518
effective HSP length: 100
effective length of query: 153
effective length of database: 14,460,918
effective search space: 2212520454
effective search space used: 2212520454
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.