Guide to the Human Genome
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Search of human proteins with 70167127

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|70167127 carbonic anhydrase VI precursor [Homo sapiens]
         (308 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|70167127 carbonic anhydrase VI precursor [Homo sapiens]            642   0.0  
gi|6912284 carbonic anhydrase XIV precursor [Homo sapiens]            193   1e-49
gi|169636420 carbonic anhydrase IX precursor [Homo sapiens]           192   2e-49
gi|45935383 carbonic anhydrase XII isoform 2 precursor [Homo sap...   186   2e-47
gi|4502515 carbonic anhydrase XII isoform 1 precursor [Homo sapi...   186   2e-47
gi|4885101 carbonic anhydrase VII isoform 1 [Homo sapiens]            155   3e-38
gi|4557395 carbonic anhydrase II [Homo sapiens]                       151   8e-37
gi|4885099 carbonic anhydrase III [Homo sapiens]                      149   2e-36
gi|38348436 carbonic anhydrase XIII [Homo sapiens]                    146   2e-35
gi|4502519 carbonic anhydrase IV precursor [Homo sapiens]             135   3e-32
gi|192447434 carbonic anhydrase I [Homo sapiens]                      135   3e-32
gi|192447432 carbonic anhydrase I [Homo sapiens]                      135   3e-32
gi|192447430 carbonic anhydrase I [Homo sapiens]                      135   3e-32
gi|4502517 carbonic anhydrase I [Homo sapiens]                        135   3e-32
gi|22027500 carbonic anhydrase VIII [Homo sapiens]                    133   2e-31
gi|91208428 protein tyrosine phosphatase, receptor-type, zeta1 p...   130   2e-30
gi|4502521 carbonic anhydrase VA, mitochondrial precursor [Homo ...   130   2e-30
gi|62240989 carbonic anhydrase VII isoform 2 [Homo sapiens]           127   2e-29
gi|194097398 protein tyrosine phosphatase, receptor type, G prec...   112   3e-25
gi|6005723 carbonic anhydrase VB, mitochondrial precursor [Homo ...   111   7e-25
gi|130979954 carbonic anhydrase X [Homo sapiens]                      103   1e-22
gi|130979679 carbonic anhydrase X [Homo sapiens]                      103   1e-22
gi|9910366 carbonic anhydrase X [Homo sapiens]                        103   1e-22
gi|9951923 carbonic anhydrase XI precursor [Homo sapiens]              89   5e-18
gi|239757628 PREDICTED: similar to hCG1646661 [Homo sapiens]           42   5e-04
gi|239752124 PREDICTED: similar to hCG1646661 [Homo sapiens]           42   5e-04
gi|239746634 PREDICTED: similar to hCG1646661 [Homo sapiens]           42   5e-04
gi|239757641 PREDICTED: similar to hCG1646661 [Homo sapiens]           42   7e-04
gi|239746647 PREDICTED: similar to hCG1646661 [Homo sapiens]           42   7e-04
gi|14917119 keratin 34 [Homo sapiens]                                  31   1.2  

>gi|70167127 carbonic anhydrase VI precursor [Homo sapiens]
          Length = 308

 Score =  642 bits (1657), Expect = 0.0
 Identities = 308/308 (100%), Positives = 308/308 (100%)

Query: 1   MRALVLLLSLFLLGGQAQHVSDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYN 60
           MRALVLLLSLFLLGGQAQHVSDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYN
Sbjct: 1   MRALVLLLSLFLLGGQAQHVSDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYN 60

Query: 61  PSLKGLNMTGYETQAGEFPMVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSE 120
           PSLKGLNMTGYETQAGEFPMVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSE
Sbjct: 61  PSLKGLNMTGYETQAGEFPMVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSE 120

Query: 121 ISGSEHTVDGIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNF 180
           ISGSEHTVDGIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNF
Sbjct: 121 ISGSEHTVDGIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNF 180

Query: 181 ISHLANIKYPGQRTTLTGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLS 240
           ISHLANIKYPGQRTTLTGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLS
Sbjct: 181 ISHLANIKYPGQRTTLTGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLS 240

Query: 241 RTQVWKLENSLLDHRNKTIHNDYRRTQPLNHRVVESNFPNQEYTLGSEFQFYLHKIEEIL 300
           RTQVWKLENSLLDHRNKTIHNDYRRTQPLNHRVVESNFPNQEYTLGSEFQFYLHKIEEIL
Sbjct: 241 RTQVWKLENSLLDHRNKTIHNDYRRTQPLNHRVVESNFPNQEYTLGSEFQFYLHKIEEIL 300

Query: 301 DYLRRALN 308
           DYLRRALN
Sbjct: 301 DYLRRALN 308


>gi|6912284 carbonic anhydrase XIV precursor [Homo sapiens]
          Length = 337

 Score =  193 bits (491), Expect = 1e-49
 Identities = 113/291 (38%), Positives = 164/291 (56%), Gaps = 14/291 (4%)

Query: 3   ALVLLLSLFLLGGQAQHVSDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPS 62
           AL+L +   L     QH   WTY EG   + HWP  YP CG   QSPI++Q   V ++P 
Sbjct: 5   ALLLEVIWILAADGGQH---WTY-EGPHGQDHWPASYPECGNNAQSPIDIQTDSVTFDPD 60

Query: 63  LKGLNMTGYETQAGE-FPMVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEI 121
           L  L   GY+    E   + NNGHTVQ+SLPST+ +       Y+A Q+H HWG   S  
Sbjct: 61  LPALQPHGYDQPGTEPLDLHNNGHTVQLSLPSTLYLGGLPRK-YVAAQLHLHWGQKGSP- 118

Query: 122 SGSEHTVDGIRHVIEIHIVHYNS-KYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNF 180
            GSEH ++      E+HIVHY+S  Y S   A + P GLAVL   +EV    +N  Y + 
Sbjct: 119 GGSEHQINSEATFAELHIVHYDSDSYDSLSEAAERPQGLAVLGILIEVGE-TKNIAYEHI 177

Query: 181 ISHLANIKYPGQRTTLTGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLS 240
           +SHL  +++  Q+T++   +++++LP+ L  Y+ Y+GSLTTPPC ++V W V     ++S
Sbjct: 178 LSHLHEVRHKDQKTSVPPFNLRELLPKQLGQYFRYNGSLTTPPCYQSVLWTVFYRRSQIS 237

Query: 241 RTQVWKLENSLL---DHRNKTIHNDYRRTQPLNHRVVESNF--PNQEYTLG 286
             Q+ KL+ +L    +  +K +  +YR  QPLN R+V ++F      YT G
Sbjct: 238 MEQLEKLQGTLFSTEEEPSKLLVQNYRALQPLNQRMVFASFIQAGSSYTTG 288


>gi|169636420 carbonic anhydrase IX precursor [Homo sapiens]
          Length = 459

 Score =  192 bits (489), Expect = 2e-49
 Identities = 103/260 (39%), Positives = 148/260 (56%), Gaps = 8/260 (3%)

Query: 21  SDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQA-GEFP 79
           S W Y      +  WP+  PAC G+ QSP++++     + P+L+ L + G++     E  
Sbjct: 139 SHWRYG----GDPPWPRVSPACAGRFQSPVDIRPQLAAFCPALRPLELLGFQLPPLPELR 194

Query: 80  MVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHI 139
           + NNGH+VQ++LP  + M +  G  Y A Q+H HWG A     GSEHTV+G R   EIH+
Sbjct: 195 LRNNGHSVQLTLPPGLEMALGPGREYRALQLHLHWGAAGRP--GSEHTVEGHRFPAEIHV 252

Query: 140 VHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTGL 199
           VH ++ +   D A   P GLAVLAAF+E +   EN+ Y   +S L  I   G  T + GL
Sbjct: 253 VHLSTAFARVDEALGRPGGLAVLAAFLE-EGPEENSAYEQLLSRLEEIAEEGSETQVPGL 311

Query: 200 DVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNKTI 259
           D+  +LP +   Y+ Y GSLTTPPC + V W V    V LS  Q+  L ++L    +  +
Sbjct: 312 DISALLPSDFSRYFQYEGSLTTPPCAQGVIWTVFNQTVMLSAKQLHTLSDTLWGPGDSRL 371

Query: 260 HNDYRRTQPLNHRVVESNFP 279
             ++R TQPLN RV+E++FP
Sbjct: 372 QLNFRATQPLNGRVIEASFP 391


>gi|45935383 carbonic anhydrase XII isoform 2 precursor [Homo
           sapiens]
          Length = 343

 Score =  186 bits (473), Expect = 2e-47
 Identities = 104/265 (39%), Positives = 149/265 (56%), Gaps = 12/265 (4%)

Query: 21  SDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAG-EFP 79
           S WTY  G   E  W + YP+CGG  QSPI+L    ++Y+ SL  L   GY   A  +F 
Sbjct: 30  SKWTYF-GPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFL 88

Query: 80  MVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHI 139
           + NNGH+V+++LPS M +       Y A Q+H HWG  +    GSEHTV G     E+HI
Sbjct: 89  LTNNGHSVKLNLPSDMHIQGLQSR-YSATQLHLHWGNPNDP-HGSEHTVSGQHFAAELHI 146

Query: 140 VHYNSK-YKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTG 198
           VHYNS  Y     A +  +GLAVLA  +E+ ++  N  Y    SHL ++KY GQ   + G
Sbjct: 147 VHYNSDLYPDASTASNKSEGLAVLAVLIEMGSF--NPSYDKIFSHLQHVKYKGQEAFVPG 204

Query: 199 LDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLL-----D 253
            +++++LP     YY Y GSLTTPPC   V W V  + V++S+ Q+  LE +L      D
Sbjct: 205 FNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDD 264

Query: 254 HRNKTIHNDYRRTQPLNHRVVESNF 278
              + + N++R+ Q  + R+V ++F
Sbjct: 265 PSPREMINNFRQVQKFDERLVYTSF 289


>gi|4502515 carbonic anhydrase XII isoform 1 precursor [Homo
           sapiens]
          Length = 354

 Score =  186 bits (473), Expect = 2e-47
 Identities = 104/265 (39%), Positives = 149/265 (56%), Gaps = 12/265 (4%)

Query: 21  SDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAG-EFP 79
           S WTY  G   E  W + YP+CGG  QSPI+L    ++Y+ SL  L   GY   A  +F 
Sbjct: 30  SKWTYF-GPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFL 88

Query: 80  MVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHI 139
           + NNGH+V+++LPS M +       Y A Q+H HWG  +    GSEHTV G     E+HI
Sbjct: 89  LTNNGHSVKLNLPSDMHIQGLQSR-YSATQLHLHWGNPNDP-HGSEHTVSGQHFAAELHI 146

Query: 140 VHYNSK-YKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTG 198
           VHYNS  Y     A +  +GLAVLA  +E+ ++  N  Y    SHL ++KY GQ   + G
Sbjct: 147 VHYNSDLYPDASTASNKSEGLAVLAVLIEMGSF--NPSYDKIFSHLQHVKYKGQEAFVPG 204

Query: 199 LDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLL-----D 253
            +++++LP     YY Y GSLTTPPC   V W V  + V++S+ Q+  LE +L      D
Sbjct: 205 FNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDD 264

Query: 254 HRNKTIHNDYRRTQPLNHRVVESNF 278
              + + N++R+ Q  + R+V ++F
Sbjct: 265 PSPREMINNFRQVQKFDERLVYTSF 289


>gi|4885101 carbonic anhydrase VII isoform 1 [Homo sapiens]
          Length = 264

 Score =  155 bits (393), Expect = 3e-38
 Identities = 97/264 (36%), Positives = 148/264 (56%), Gaps = 16/264 (6%)

Query: 23  WTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMVN 82
           W Y +     +HW + YP   G RQSPIN+  ++  Y+PSL+ L ++ YE       + N
Sbjct: 7   WGYGQDD-GPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELS-YEA-CMSLSITN 63

Query: 83  NGHTVQISLPSTMRMTVADGTV----YIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIH 138
           NGH+VQ+    +   TV  G      Y  +Q HFHWG       GSEHTVDG     E+H
Sbjct: 64  NGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWG--KKHDVGSEHTVDGKSFPSELH 121

Query: 139 IVHYNSK-YKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLT 197
           +VH+N+K Y ++  A  APDGLAV+  F+E  +  E+   +     L  +++ G +   +
Sbjct: 122 LVHWNAKKYSTFGEAASAPDGLAVVGVFLETGD--EHPSMNRLTDALYMVRFKGTKAQFS 179

Query: 198 GLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLL-DHRN 256
             + + +LP + +HY+TY GSLTTPP +E+V W VL + + +S  Q+ K  + L     +
Sbjct: 180 CFNPKCLLPAS-RHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDD 238

Query: 257 KTIH--NDYRRTQPLNHRVVESNF 278
           + IH  N++R  QPL  RVV+++F
Sbjct: 239 ERIHMVNNFRPPQPLKGRVVKASF 262


>gi|4557395 carbonic anhydrase II [Homo sapiens]
          Length = 260

 Score =  151 bits (381), Expect = 8e-37
 Identities = 93/264 (35%), Positives = 142/264 (53%), Gaps = 17/264 (6%)

Query: 23  WTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMVN 82
           W Y +    E HW + +P   G+RQSP+++     +Y+PSLK L+++ Y+ QA    ++N
Sbjct: 5   WGYGKHNGPE-HWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVS-YD-QATSLRILN 61

Query: 83  NGHTVQISLPSTMRMTVA-----DGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEI 137
           NGH   +    +    V      DGT Y   Q HFHWG    +  GSEHTVD  ++  E+
Sbjct: 62  NGHAFNVEFDDSQDKAVLKGGPLDGT-YRLIQFHFHWGSLDGQ--GSEHTVDKKKYAAEL 118

Query: 138 HIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLT 197
           H+VH+N+KY  +  A   PDGLAVL  F++V +          +  L +IK  G+    T
Sbjct: 119 HLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPG--LQKVVDVLDSIKTKGKSADFT 176

Query: 198 GLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLD---H 254
             D + +LP +L  Y+TY GSLTTPP  E V W VL + + +S  QV K      +    
Sbjct: 177 NFDPRGLLPESLD-YWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGE 235

Query: 255 RNKTIHNDYRRTQPLNHRVVESNF 278
             + + +++R  QPL +R ++++F
Sbjct: 236 PEELMVDNWRPAQPLKNRQIKASF 259


>gi|4885099 carbonic anhydrase III [Homo sapiens]
          Length = 260

 Score =  149 bits (377), Expect = 2e-36
 Identities = 85/252 (33%), Positives = 143/252 (56%), Gaps = 14/252 (5%)

Query: 34  HWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMVNNGHTVQISLPS 93
           HW + +P   G+ QSP+ L    +R++PSL+  +++ Y+  + +  ++NNG T ++    
Sbjct: 15  HWHELFPNAKGENQSPVELHTKDIRHDPSLQPWSVS-YDGGSAK-TILNNGKTCRVVFDD 72

Query: 94  TMRMTVADGTV----YIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHIVHYNSKYKSY 149
           T   ++  G      Y  +Q H HWG  SS+  GSEHTVDG+++  E+H+VH+N KY ++
Sbjct: 73  TYDRSMLRGGPLPGPYRLRQFHLHWG--SSDDHGSEHTVDGVKYAAELHLVHWNPKYNTF 130

Query: 150 DIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTGLDVQDMLPRNL 209
             A    DG+AV+  F+++ +  EN  +  F+  L  IK  G+    T  D   + P   
Sbjct: 131 KEALKQRDGIAVIGIFLKIGH--ENGEFQIFLDALDKIKTKGKEAPFTKFDPSCLFPA-C 187

Query: 210 QHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNK---TIHNDYRRT 266
           + Y+TY GS TTPPC E + W +L + + +S  Q+ KL + L    N+    + +++R  
Sbjct: 188 RDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPLVSNWRPP 247

Query: 267 QPLNHRVVESNF 278
           QP+N+RVV ++F
Sbjct: 248 QPINNRVVRASF 259


>gi|38348436 carbonic anhydrase XIII [Homo sapiens]
          Length = 262

 Score =  146 bits (369), Expect = 2e-35
 Identities = 90/264 (34%), Positives = 140/264 (53%), Gaps = 16/264 (6%)

Query: 23  WTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMVN 82
           W Y E      HW + +P   G +QSPI ++  +V+Y+ SL+ L++  Y+  + +  + N
Sbjct: 6   WGYREHN-GPIHWKEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIK-YDPSSAKI-ISN 62

Query: 83  NGHTVQISLPSTMRMTVADGTV----YIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIH 138
           +GH+  +    T   +V  G      Y  +Q+H HWG A     GSEH VDG+ +  E+H
Sbjct: 63  SGHSFNVDFDDTENKSVLRGGPLTGSYRLRQVHLHWGSADDH--GSEHIVDGVSYAAELH 120

Query: 139 IVHYNS-KYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLT 197
           +VH+NS KY S+  A   PDGLAVL  F+++     N+        L +IK  G++T  T
Sbjct: 121 VVHWNSDKYPSFVEAAHEPDGLAVLGVFLQIGE--PNSQLQKITDTLDSIKEKGKQTRFT 178

Query: 198 GLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNK 257
             D+  +LP +   Y+TY GSLT PP  E+V W VL   + +S  Q+ K  + L     +
Sbjct: 179 NFDLLSLLPPSWD-YWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGE 237

Query: 258 T---IHNDYRRTQPLNHRVVESNF 278
               + +++R  QPL  R V ++F
Sbjct: 238 AAAFLVSNHRPPQPLKGRKVRASF 261


>gi|4502519 carbonic anhydrase IV precursor [Homo sapiens]
          Length = 312

 Score =  135 bits (341), Expect = 3e-32
 Identities = 98/296 (33%), Positives = 151/296 (51%), Gaps = 22/296 (7%)

Query: 1   MRALVLLLSLFLLGGQAQHVSDWTYSEGALDEAHWPQHYPA-----CGGQRQSPINLQRT 55
           MR L+ LL+L      A   S W Y   A + +++P   P      C   RQSPIN+  T
Sbjct: 1   MRMLLALLALSAARPSASAESHWCYEVQA-ESSNYPCLVPVKWGGNCQKDRQSPINIVTT 59

Query: 56  KVRYNPSLKGLNMTGYETQAGEFPMVNNGHTVQISLPSTMRMTVADGTV---YIAQQMHF 112
           K + +  L     +GY+ +   + + NNGH+V + L +  + +++ G +   Y A+Q+H 
Sbjct: 60  KAKVDKKLGRFFFSGYDKKQ-TWTVQNNGHSVMMLLEN--KASISGGGLPAPYQAKQLHL 116

Query: 113 HWGGASSEISGSEHTVDGIRHVIEIHIVHYNSKYKSYDI--AQDAPDGLAVLAAFVEVKN 170
           HW  +     GSEH++DG    +E+HIVH   K  S ++  AQD  D +AVLA  VE   
Sbjct: 117 HW--SDLPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGT 174

Query: 171 YPENTYYSNFISHLANIKYPGQRTTLTGLDVQDMLPRN--LQHYYTYHGSLTTPPCTENV 228
              N  +   +  L+NI  P   TT+    + D+LP+   L+HY+ Y GSLTTP C E V
Sbjct: 175 QV-NEGFQPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKV 233

Query: 229 HWFVLADFVKLSRTQVWKLENSLLDHRNKTI--HNDYRRTQPLNHR-VVESNFPNQ 281
            W V  + ++L R Q+      L   + +T+   ++ R  Q L  R V++S  P +
Sbjct: 234 VWTVFREPIQLHREQILAFSQKLYYDKEQTVSMKDNVRPLQQLGQRTVIKSGAPGR 289


>gi|192447434 carbonic anhydrase I [Homo sapiens]
          Length = 261

 Score =  135 bits (341), Expect = 3e-32
 Identities = 88/266 (33%), Positives = 136/266 (51%), Gaps = 18/266 (6%)

Query: 22  DWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMV 81
           DW Y +    E  W + YP   G  QSP++++ ++ +++ SLK ++++     A E  ++
Sbjct: 5   DWGYDDKNGPE-QWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKE--II 61

Query: 82  NNGHTVQISLPSTMRMTVADG----TVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEI 137
           N GH+  ++       +V  G      Y   Q HFHWG  +    GSEHTVDG+++  E+
Sbjct: 62  NVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEH--GSEHTVDGVKYSAEL 119

Query: 138 HIVHYNS-KYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTL 196
           H+ H+NS KY S   A    DGLAV+   ++V     N      +  L  IK  G+R   
Sbjct: 120 HVAHWNSAKYSSLAEAASKADGLAVIGVLMKVGE--ANPKLQKVLDALQAIKTKGKRAPF 177

Query: 197 TGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWK----LENSLL 252
           T  D   +LP +L  ++TY GSLT PP  E+V W +  + + +S  Q+ +    L N   
Sbjct: 178 TNFDPSTLLPSSLD-FWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEG 236

Query: 253 DHRNKTIHNDYRRTQPLNHRVVESNF 278
           D+     HN+ R TQPL  R V ++F
Sbjct: 237 DNAVPMQHNN-RPTQPLKGRTVRASF 261


>gi|192447432 carbonic anhydrase I [Homo sapiens]
          Length = 261

 Score =  135 bits (341), Expect = 3e-32
 Identities = 88/266 (33%), Positives = 136/266 (51%), Gaps = 18/266 (6%)

Query: 22  DWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMV 81
           DW Y +    E  W + YP   G  QSP++++ ++ +++ SLK ++++     A E  ++
Sbjct: 5   DWGYDDKNGPE-QWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKE--II 61

Query: 82  NNGHTVQISLPSTMRMTVADG----TVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEI 137
           N GH+  ++       +V  G      Y   Q HFHWG  +    GSEHTVDG+++  E+
Sbjct: 62  NVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEH--GSEHTVDGVKYSAEL 119

Query: 138 HIVHYNS-KYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTL 196
           H+ H+NS KY S   A    DGLAV+   ++V     N      +  L  IK  G+R   
Sbjct: 120 HVAHWNSAKYSSLAEAASKADGLAVIGVLMKVGE--ANPKLQKVLDALQAIKTKGKRAPF 177

Query: 197 TGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWK----LENSLL 252
           T  D   +LP +L  ++TY GSLT PP  E+V W +  + + +S  Q+ +    L N   
Sbjct: 178 TNFDPSTLLPSSLD-FWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEG 236

Query: 253 DHRNKTIHNDYRRTQPLNHRVVESNF 278
           D+     HN+ R TQPL  R V ++F
Sbjct: 237 DNAVPMQHNN-RPTQPLKGRTVRASF 261


>gi|192447430 carbonic anhydrase I [Homo sapiens]
          Length = 261

 Score =  135 bits (341), Expect = 3e-32
 Identities = 88/266 (33%), Positives = 136/266 (51%), Gaps = 18/266 (6%)

Query: 22  DWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMV 81
           DW Y +    E  W + YP   G  QSP++++ ++ +++ SLK ++++     A E  ++
Sbjct: 5   DWGYDDKNGPE-QWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKE--II 61

Query: 82  NNGHTVQISLPSTMRMTVADG----TVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEI 137
           N GH+  ++       +V  G      Y   Q HFHWG  +    GSEHTVDG+++  E+
Sbjct: 62  NVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEH--GSEHTVDGVKYSAEL 119

Query: 138 HIVHYNS-KYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTL 196
           H+ H+NS KY S   A    DGLAV+   ++V     N      +  L  IK  G+R   
Sbjct: 120 HVAHWNSAKYSSLAEAASKADGLAVIGVLMKVGE--ANPKLQKVLDALQAIKTKGKRAPF 177

Query: 197 TGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWK----LENSLL 252
           T  D   +LP +L  ++TY GSLT PP  E+V W +  + + +S  Q+ +    L N   
Sbjct: 178 TNFDPSTLLPSSLD-FWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEG 236

Query: 253 DHRNKTIHNDYRRTQPLNHRVVESNF 278
           D+     HN+ R TQPL  R V ++F
Sbjct: 237 DNAVPMQHNN-RPTQPLKGRTVRASF 261


>gi|4502517 carbonic anhydrase I [Homo sapiens]
          Length = 261

 Score =  135 bits (341), Expect = 3e-32
 Identities = 88/266 (33%), Positives = 136/266 (51%), Gaps = 18/266 (6%)

Query: 22  DWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMV 81
           DW Y +    E  W + YP   G  QSP++++ ++ +++ SLK ++++     A E  ++
Sbjct: 5   DWGYDDKNGPE-QWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKE--II 61

Query: 82  NNGHTVQISLPSTMRMTVADG----TVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEI 137
           N GH+  ++       +V  G      Y   Q HFHWG  +    GSEHTVDG+++  E+
Sbjct: 62  NVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEH--GSEHTVDGVKYSAEL 119

Query: 138 HIVHYNS-KYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTL 196
           H+ H+NS KY S   A    DGLAV+   ++V     N      +  L  IK  G+R   
Sbjct: 120 HVAHWNSAKYSSLAEAASKADGLAVIGVLMKVGE--ANPKLQKVLDALQAIKTKGKRAPF 177

Query: 197 TGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWK----LENSLL 252
           T  D   +LP +L  ++TY GSLT PP  E+V W +  + + +S  Q+ +    L N   
Sbjct: 178 TNFDPSTLLPSSLD-FWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEG 236

Query: 253 DHRNKTIHNDYRRTQPLNHRVVESNF 278
           D+     HN+ R TQPL  R V ++F
Sbjct: 237 DNAVPMQHNN-RPTQPLKGRTVRASF 261


>gi|22027500 carbonic anhydrase VIII [Homo sapiens]
          Length = 290

 Score =  133 bits (334), Expect = 2e-31
 Identities = 82/270 (30%), Positives = 140/270 (51%), Gaps = 21/270 (7%)

Query: 22  DWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMV 81
           +W Y EG      W   +P   G+ QSPINL   + RY+PSL  + ++       +  + 
Sbjct: 28  EWGYEEGV----EWGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSPNYVVCRDCEVT 83

Query: 82  NNGHTVQISLPSTMRMT---VADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIH 138
           N+GHT+Q+ L S   ++   +  G  +   ++ FHWG  +    GSEHTV+     +E+H
Sbjct: 84  NDGHTIQVILKSKSVLSGGPLPQGHEFELYEVRFHWGRENQR--GSEHTVNFKAFPMELH 141

Query: 139 IVHYNSK-YKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLT 197
           ++H+NS  + S D A   P G+A++A FV++    E+         L +I+Y G+  T+ 
Sbjct: 142 LIHWNSTLFGSIDEAVGKPHGIAIIALFVQIGK--EHVGLKAVTEILQDIQYKGKSKTIP 199

Query: 198 GLDVQDMLPRN-LQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLEN------- 249
             +   +LP   L+ Y+ Y GSLT PPC+E V W +    + +S+ Q+ +          
Sbjct: 200 CFNPNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKG 259

Query: 250 -SLLDHRNKTIHNDYRRTQPLNHRVVESNF 278
             L++  +  + +++R TQPL+ RV+ + F
Sbjct: 260 AELVEGCDGILGDNFRPTQPLSDRVIRAAF 289


>gi|91208428 protein tyrosine phosphatase, receptor-type, zeta1
           precursor [Homo sapiens]
          Length = 2315

 Score =  130 bits (326), Expect = 2e-30
 Identities = 82/273 (30%), Positives = 145/273 (53%), Gaps = 19/273 (6%)

Query: 23  WTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMVN 82
           W+Y+ GAL++ +W + YP C   +QSPIN+     + N +LK L   G++  + E   ++
Sbjct: 38  WSYT-GALNQKNWGKKYPTCNSPKQSPINIDEDLTQVNVNLKKLKFQGWDKTSLENTFIH 96

Query: 83  N-GHTVQISLPSTMRMTVA-DGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHIV 140
           N G TV+I+L +  R++      V+ A ++ FHWG  +    GSEH+++G +  +E+ I 
Sbjct: 97  NTGKTVEINLTNDYRVSGGVSEMVFKASKITFHWGKCNMSSDGSEHSLEGQKFPLEMQIY 156

Query: 141 HYNS-KYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTGL 199
            +++ ++ S++ A      L  L+   EV    EN  +   I  + ++   G++  L   
Sbjct: 157 CFDADRFSSFEEAVKGKGKLRALSILFEVGT-EENLDFKAIIDGVESVSRFGKQAALDPF 215

Query: 200 DVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQ------VWKLENS--- 250
            + ++LP +   YY Y+GSLT+PPCT+ V W V  D V +S +Q      V  ++ S   
Sbjct: 216 ILLNLLPNSTDKYYIYNGSLTSPPCTDTVDWIVFKDTVSISESQLAVFCEVLTMQQSGYV 275

Query: 251 -LLDHRNKTIHNDYRRTQPLNHRVVESNFPNQE 282
            L+D+    + N++R  Q    R V S++  +E
Sbjct: 276 MLMDY----LQNNFREQQYKFSRQVFSSYTGKE 304


>gi|4502521 carbonic anhydrase VA, mitochondrial precursor [Homo
           sapiens]
          Length = 305

 Score =  130 bits (326), Expect = 2e-30
 Identities = 90/270 (33%), Positives = 134/270 (49%), Gaps = 16/270 (5%)

Query: 17  AQHVSDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAG 76
           +Q    W  S   L    W       GG RQSPIN+Q     Y+P LK L ++ YE  + 
Sbjct: 35  SQRSCAWQTSNNTLHPL-WTVPVSVPGGTRQSPINIQWRDSVYDPQLKPLRVS-YEAASC 92

Query: 77  EFPMVNNGHTVQISLPSTMRMTVADG----TVYIAQQMHFHWGGASSEISGSEHTVDGIR 132
            + + N G+  Q+        +   G      Y  +Q HFHWG  +    GSEHTVDG  
Sbjct: 93  LY-IWNTGYLFQVEFDDATEASGISGGPLENHYRLKQFHFHWGAVNE--GGSEHTVDGHA 149

Query: 133 HVIEIHIVHYNS-KYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPG 191
           +  E+H+VH+NS KY++Y  A    +GLAV+  F+++  + +       +  L  IK+  
Sbjct: 150 YPAELHLVHWNSVKYQNYKEAVVGENGLAVIGVFLKLGAHHQTL--QRLVDILPEIKHKD 207

Query: 192 QRTTLTGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLEN-- 249
            R  +   D   +LP     Y+TY GSLTTPP TE+V W +  + V+++ +Q+       
Sbjct: 208 ARAAMRPFDPSTLLP-TCWDYWTYAGSLTTPPLTESVTWIIQKEPVEVAPSQLSAFRTLL 266

Query: 250 -SLLDHRNKTIHNDYRRTQPLNHRVVESNF 278
            S L    K + N+YR  QPL +R V ++F
Sbjct: 267 FSALGEEEKMMVNNYRPLQPLMNRKVWASF 296


>gi|62240989 carbonic anhydrase VII isoform 2 [Homo sapiens]
          Length = 208

 Score =  127 bits (318), Expect = 2e-29
 Identities = 77/207 (37%), Positives = 118/207 (57%), Gaps = 13/207 (6%)

Query: 80  MVNNGHTVQISLPSTMRMTVADGTV----YIAQQMHFHWGGASSEISGSEHTVDGIRHVI 135
           + NNGH+VQ+    +   TV  G      Y  +Q HFHWG       GSEHTVDG     
Sbjct: 5   ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWG--KKHDVGSEHTVDGKSFPS 62

Query: 136 EIHIVHYNSK-YKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRT 194
           E+H+VH+N+K Y ++  A  APDGLAV+  F+E  +  E+   +     L  +++ G + 
Sbjct: 63  ELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGD--EHPSMNRLTDALYMVRFKGTKA 120

Query: 195 TLTGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLL-D 253
             +  + + +LP + +HY+TY GSLTTPP +E+V W VL + + +S  Q+ K  + L   
Sbjct: 121 QFSCFNPKCLLPAS-RHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTS 179

Query: 254 HRNKTIH--NDYRRTQPLNHRVVESNF 278
             ++ IH  N++R  QPL  RVV+++F
Sbjct: 180 EDDERIHMVNNFRPPQPLKGRVVKASF 206


>gi|194097398 protein tyrosine phosphatase, receptor type, G
           precursor [Homo sapiens]
          Length = 1445

 Score =  112 bits (281), Expect = 3e-25
 Identities = 81/264 (30%), Positives = 128/264 (48%), Gaps = 12/264 (4%)

Query: 23  WTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFP-MV 81
           W YS GA    HW     +CGG+ QSPI++     R     + L + G++ ++     M 
Sbjct: 60  WAYS-GAYGPEHWVTSSVSCGGRHQSPIDILDQYARVGEEYQELQLDGFDNESSNKTWMK 118

Query: 82  NNGHTVQISLPSTMRMTVAD-GTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHIV 140
           N G TV I L     ++ A     + A+++ FHWG ++   +GSEH+++G R  +E+ I 
Sbjct: 119 NTGKTVAILLKDDYFVSGAGLPGRFKAEKVEFHWGHSNGS-AGSEHSINGRRFPVEMQIF 177

Query: 141 HYN-SKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTGL 199
            YN   + S+  A      +  +A F +V    +N+     I  L  + +  + T L   
Sbjct: 178 FYNPDDFDSFQTAISENRIIGAMAIFFQVSPR-DNSALDPIIHGLKGVVHHEKETFLDPF 236

Query: 200 DVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLL----DHR 255
            ++D+LP +L  YY Y GSLTTPPC+E V W V    V +S  Q+    +       DH 
Sbjct: 237 VLRDLLPASLGSYYRYTGSLTTPPCSEIVEWIVFRRPVPISYHQLEAFYSIFTTEQQDHV 296

Query: 256 NKT--IHNDYRRTQPLNHRVVESN 277
                + N++R  Q L+ RVV  +
Sbjct: 297 KSVEYLRNNFRPQQRLHDRVVSKS 320


>gi|6005723 carbonic anhydrase VB, mitochondrial precursor [Homo
           sapiens]
          Length = 317

 Score =  111 bits (278), Expect = 7e-25
 Identities = 78/251 (31%), Positives = 131/251 (52%), Gaps = 16/251 (6%)

Query: 43  GGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMVNNGHTVQISLP-STMRMTVAD 101
           GG RQSPIN++     Y+P LK L ++ Y+  A    + NNG++  +    ST +  +  
Sbjct: 60  GGDRQSPINIRWRDSVYDPGLKPLTIS-YDP-ATCLHVWNNGYSFLVEFEDSTDKSVIKG 117

Query: 102 GTV---YIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHIVHYNS-KYKSYDIAQDAPD 157
           G +   Y  +Q HFHWG   +   GSEHTVD      E+H+VH+N+ ++++++ A    +
Sbjct: 118 GPLEHNYRLKQFHFHWGAIDAW--GSEHTVDSKCFPAELHLVHWNAVRFENFEDAALEEN 175

Query: 158 GLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTGLDVQDMLPRNLQHYYTYHG 217
           GLAV+  F+++  + +       +  L +IK+          D   ++P     Y+TY G
Sbjct: 176 GLAVIGVFLKLGKHHKEL--QKLVDTLPSIKHKDALVEFGSFDPSCLMP-TCPDYWTYSG 232

Query: 218 SLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLL---DHRNKTIHNDYRRTQPLNHRVV 274
           SLTTPP +E+V W +    V++   Q+ +    L      + K + +++R  QPL +R V
Sbjct: 233 SLTTPPLSESVTWIIKKQPVEVDHDQLEQFRTLLFTSEGEKEKRMVDNFRPLQPLMNRTV 292

Query: 275 ESNFPNQEYTL 285
            S+F   +Y L
Sbjct: 293 RSSF-RHDYVL 302


>gi|130979954 carbonic anhydrase X [Homo sapiens]
          Length = 328

 Score =  103 bits (258), Expect = 1e-22
 Identities = 68/246 (27%), Positives = 128/246 (52%), Gaps = 20/246 (8%)

Query: 44  GQRQSPINLQRTKVRYNPSLKGLNM-TGYETQAGEFPMVNNGHTVQISLPSTMRMTVADG 102
           G+RQSP+N++ + + ++P L  L + TG    +G   M N G  V + L     + ++ G
Sbjct: 63  GKRQSPVNIETSHMIFDPFLTPLRINTGGRKVSGT--MYNTGRHVSLRLDKEHLVNISGG 120

Query: 103 TVYIA---QQMHFHWGGASSEISGSEHTVDGIRHVIEIHIVHYNSK-YKSYDIAQDAPDG 158
            +  +   +++  H+G   S+  GSEH ++G     E+ ++HYN + Y +   A  +P+G
Sbjct: 121 PMTYSHRLEEIRLHFGSEDSQ--GSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNG 178

Query: 159 LAVLAAFVEVKNYPENTYYSNFISH--LANIKYPGQRTTLTGLDVQDMLPRNLQHYYTYH 216
           L V++ F++V +   N + +  ++   +  I Y      L GL+++++ P     + TY 
Sbjct: 179 LVVVSIFIKVSD-SSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPET-SSFITYD 236

Query: 217 GSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNK-----TIHNDYRRTQPLNH 271
           GS+T PPC E   W ++   V ++R Q+  L   LL          ++ +++R  QPLN+
Sbjct: 237 GSMTIPPCYETASWIIMNKPVYITRMQMHSLR--LLSQNQPSQIFLSMSDNFRPVQPLNN 294

Query: 272 RVVESN 277
           R + +N
Sbjct: 295 RCIRTN 300


>gi|130979679 carbonic anhydrase X [Homo sapiens]
          Length = 328

 Score =  103 bits (258), Expect = 1e-22
 Identities = 68/246 (27%), Positives = 128/246 (52%), Gaps = 20/246 (8%)

Query: 44  GQRQSPINLQRTKVRYNPSLKGLNM-TGYETQAGEFPMVNNGHTVQISLPSTMRMTVADG 102
           G+RQSP+N++ + + ++P L  L + TG    +G   M N G  V + L     + ++ G
Sbjct: 63  GKRQSPVNIETSHMIFDPFLTPLRINTGGRKVSGT--MYNTGRHVSLRLDKEHLVNISGG 120

Query: 103 TVYIA---QQMHFHWGGASSEISGSEHTVDGIRHVIEIHIVHYNSK-YKSYDIAQDAPDG 158
            +  +   +++  H+G   S+  GSEH ++G     E+ ++HYN + Y +   A  +P+G
Sbjct: 121 PMTYSHRLEEIRLHFGSEDSQ--GSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNG 178

Query: 159 LAVLAAFVEVKNYPENTYYSNFISH--LANIKYPGQRTTLTGLDVQDMLPRNLQHYYTYH 216
           L V++ F++V +   N + +  ++   +  I Y      L GL+++++ P     + TY 
Sbjct: 179 LVVVSIFIKVSD-SSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPET-SSFITYD 236

Query: 217 GSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNK-----TIHNDYRRTQPLNH 271
           GS+T PPC E   W ++   V ++R Q+  L   LL          ++ +++R  QPLN+
Sbjct: 237 GSMTIPPCYETASWIIMNKPVYITRMQMHSLR--LLSQNQPSQIFLSMSDNFRPVQPLNN 294

Query: 272 RVVESN 277
           R + +N
Sbjct: 295 RCIRTN 300


>gi|9910366 carbonic anhydrase X [Homo sapiens]
          Length = 328

 Score =  103 bits (258), Expect = 1e-22
 Identities = 68/246 (27%), Positives = 128/246 (52%), Gaps = 20/246 (8%)

Query: 44  GQRQSPINLQRTKVRYNPSLKGLNM-TGYETQAGEFPMVNNGHTVQISLPSTMRMTVADG 102
           G+RQSP+N++ + + ++P L  L + TG    +G   M N G  V + L     + ++ G
Sbjct: 63  GKRQSPVNIETSHMIFDPFLTPLRINTGGRKVSGT--MYNTGRHVSLRLDKEHLVNISGG 120

Query: 103 TVYIA---QQMHFHWGGASSEISGSEHTVDGIRHVIEIHIVHYNSK-YKSYDIAQDAPDG 158
            +  +   +++  H+G   S+  GSEH ++G     E+ ++HYN + Y +   A  +P+G
Sbjct: 121 PMTYSHRLEEIRLHFGSEDSQ--GSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNG 178

Query: 159 LAVLAAFVEVKNYPENTYYSNFISH--LANIKYPGQRTTLTGLDVQDMLPRNLQHYYTYH 216
           L V++ F++V +   N + +  ++   +  I Y      L GL+++++ P     + TY 
Sbjct: 179 LVVVSIFIKVSD-SSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPET-SSFITYD 236

Query: 217 GSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNK-----TIHNDYRRTQPLNH 271
           GS+T PPC E   W ++   V ++R Q+  L   LL          ++ +++R  QPLN+
Sbjct: 237 GSMTIPPCYETASWIIMNKPVYITRMQMHSLR--LLSQNQPSQIFLSMSDNFRPVQPLNN 294

Query: 272 RVVESN 277
           R + +N
Sbjct: 295 RCIRTN 300


>gi|9951923 carbonic anhydrase XI precursor [Homo sapiens]
          Length = 328

 Score = 89.0 bits (219), Expect = 5e-18
 Identities = 66/244 (27%), Positives = 119/244 (48%), Gaps = 16/244 (6%)

Query: 44  GQRQSPINLQRTKVRYNPSLKGLNM-TGYETQAGEFPMVNNGHTVQISLPSTMRMTVADG 102
           G+RQSP++++  +V Y+P L  L + TG E   G   + N G  V         + V+ G
Sbjct: 65  GKRQSPVDVELKRVLYDPFLPPLRLSTGGEKLRGT--LYNTGRHVSFLPAPRPVVNVSGG 122

Query: 103 TVYIAQQM-HFHWGGASSEISGSEHTVDGIRHVIEIHIVHYNSK-YKSYDIAQDAPDGLA 160
            +  + ++        + + +GSEH ++      E+ ++H+N + Y ++  A   P+GLA
Sbjct: 123 PLLYSHRLSELRLLFGARDGAGSEHQINHQGFSAEVQLIHFNQELYGNFSAASRGPNGLA 182

Query: 161 VLAAFVEVKNYPENTYYSNFISH--LANIKYPGQRTTLTGLDVQDMLPRNLQHYYTYHGS 218
           +L+ FV V +   N + S  ++   +  I Y      L  L ++ + P +   + TY GS
Sbjct: 183 ILSLFVNVAS-TSNPFLSRLLNRDTITRISYKNDAYFLQDLSLELLFPESFG-FITYQGS 240

Query: 219 LTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRN-----KTIHNDYRRTQPLNHRV 273
           L+TPPC+E V W ++   + ++  Q+  L   LL         +++  + R  QPL HR 
Sbjct: 241 LSTPPCSETVTWILIDRALNITSLQMHSLR--LLSQNPPSQIFQSLSGNSRPLQPLAHRA 298

Query: 274 VESN 277
           +  N
Sbjct: 299 LRGN 302


>gi|239757628 PREDICTED: similar to hCG1646661 [Homo sapiens]
          Length = 190

 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 35/137 (25%), Positives = 57/137 (41%), Gaps = 16/137 (11%)

Query: 114 WGGASSEISGSEHTVDGIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVK---- 169
           WGG S+     E          ++H+VH N+KY+S + A    DGL              
Sbjct: 9   WGGRSAPTEVRES---------KMHVVHSNTKYQSMEEAPRHGDGLECRPCCWRTPRTWS 59

Query: 170 -NYPENTYYSNFISHLANI-KYPGQRTTLTGLDVQDMLPRNLQHYYTYHGSLTTPPCTEN 227
            +  ++   +NF + ++ + K P     ++   +  M P N   Y  + GSLT P C   
Sbjct: 60  PSQEQDCSNTNFCAIVSGLRKVPEPVNLMSTFPLASMRP-NTSSYCRFAGSLTPPDCEPT 118

Query: 228 VHWFVLADFVKLSRTQV 244
           V W V  D + +   Q+
Sbjct: 119 VLWTVFEDPIPIRWVQM 135


>gi|239752124 PREDICTED: similar to hCG1646661 [Homo sapiens]
          Length = 190

 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 35/137 (25%), Positives = 57/137 (41%), Gaps = 16/137 (11%)

Query: 114 WGGASSEISGSEHTVDGIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVK---- 169
           WGG S+     E          ++H+VH N+KY+S + A    DGL              
Sbjct: 9   WGGRSAPTEVRES---------KMHVVHSNTKYQSMEEAPRHGDGLECRPCCWRTPRTWS 59

Query: 170 -NYPENTYYSNFISHLANI-KYPGQRTTLTGLDVQDMLPRNLQHYYTYHGSLTTPPCTEN 227
            +  ++   +NF + ++ + K P     ++   +  M P N   Y  + GSLT P C   
Sbjct: 60  PSQEQDCSNTNFCAIVSGLRKVPEPVNLMSTFPLASMRP-NTSSYCRFAGSLTPPDCEPT 118

Query: 228 VHWFVLADFVKLSRTQV 244
           V W V  D + +   Q+
Sbjct: 119 VLWTVFEDPIPIRWVQM 135


>gi|239746634 PREDICTED: similar to hCG1646661 [Homo sapiens]
          Length = 190

 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 35/137 (25%), Positives = 57/137 (41%), Gaps = 16/137 (11%)

Query: 114 WGGASSEISGSEHTVDGIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVK---- 169
           WGG S+     E          ++H+VH N+KY+S + A    DGL              
Sbjct: 9   WGGRSAPTEVRES---------KMHVVHSNTKYQSMEEAPRHGDGLECRPCCWRTPRTWS 59

Query: 170 -NYPENTYYSNFISHLANI-KYPGQRTTLTGLDVQDMLPRNLQHYYTYHGSLTTPPCTEN 227
            +  ++   +NF + ++ + K P     ++   +  M P N   Y  + GSLT P C   
Sbjct: 60  PSQEQDCSNTNFCAIVSGLRKVPEPVNLMSTFPLASMRP-NTSSYCRFAGSLTPPDCEPT 118

Query: 228 VHWFVLADFVKLSRTQV 244
           V W V  D + +   Q+
Sbjct: 119 VLWTVFEDPIPIRWVQM 135


>gi|239757641 PREDICTED: similar to hCG1646661 [Homo sapiens]
          Length = 190

 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 32/136 (23%), Positives = 55/136 (40%), Gaps = 14/136 (10%)

Query: 114 WGGASSEISGSEHTVDGIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVK---- 169
           WGG S+     E          ++H+VH N+KY+S + A    DGL              
Sbjct: 9   WGGRSAPTEMRES---------KMHVVHSNTKYQSMEEAPRHGDGLECRPCCWRTPRTWS 59

Query: 170 -NYPENTYYSNFISHLANIKYPGQRTTLTGLDVQDMLPRNLQHYYTYHGSLTTPPCTENV 228
            +  ++   +NF + ++ ++   +   L    +   +  N   Y  + GSLT P C   V
Sbjct: 60  PSQEQDCSNTNFCAIVSGLRKVPEPVNLRSTFLLASMRPNTSSYCRFAGSLTPPDCEPTV 119

Query: 229 HWFVLADFVKLSRTQV 244
            W V  D + +   Q+
Sbjct: 120 LWTVFEDPIPIRWVQM 135


>gi|239746647 PREDICTED: similar to hCG1646661 [Homo sapiens]
          Length = 190

 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 32/136 (23%), Positives = 55/136 (40%), Gaps = 14/136 (10%)

Query: 114 WGGASSEISGSEHTVDGIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVK---- 169
           WGG S+     E          ++H+VH N+KY+S + A    DGL              
Sbjct: 9   WGGRSAPTEMRES---------KMHVVHSNTKYQSMEEAPRHGDGLECRPCCWRTPCTWS 59

Query: 170 -NYPENTYYSNFISHLANIKYPGQRTTLTGLDVQDMLPRNLQHYYTYHGSLTTPPCTENV 228
            +  ++   +NF + ++ ++   +   L    +   +  N   Y  + GSLT P C   V
Sbjct: 60  PSQEQDCSNTNFCAIVSGLRKVPEPVNLMSTFLLASMRPNTSSYCRFAGSLTPPDCEPTV 119

Query: 229 HWFVLADFVKLSRTQV 244
            W V  D + +   Q+
Sbjct: 120 LWTVFEDPIPIRWVQM 135


>gi|14917119 keratin 34 [Homo sapiens]
          Length = 436

 Score = 31.2 bits (69), Expect = 1.2
 Identities = 21/89 (23%), Positives = 33/89 (37%), Gaps = 2/89 (2%)

Query: 211 HYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNKTIHNDYRRTQPLN 270
           H YT  G+   P    N +WF    F    +  +  L + L  +  K       R     
Sbjct: 69  HGYTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKV--RQLERDNAEL 126

Query: 271 HRVVESNFPNQEYTLGSEFQFYLHKIEEI 299
            ++++     QE  L   +Q Y   IEE+
Sbjct: 127 EKLIQERSQQQEPLLCPSYQSYFKTIEEL 155


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.413 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,767,084
Number of Sequences: 37866
Number of extensions: 507520
Number of successful extensions: 1138
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1008
Number of HSP's gapped (non-prelim): 37
length of query: 308
length of database: 18,247,518
effective HSP length: 102
effective length of query: 206
effective length of database: 14,385,186
effective search space: 2963348316
effective search space used: 2963348316
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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