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Search of human proteins with 13786123
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13786123 HMG-box transcription factor TCF-3 [Homo sapiens]
(588 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13786123 HMG-box transcription factor TCF-3 [Homo sapiens] 1197 0.0
gi|226371625 transcription factor 7-like 2 isoform 5 [Homo sapiens] 671 0.0
gi|170014696 transcription factor 7-like 2 isoform 2 [Homo sapiens] 665 0.0
gi|226371764 transcription factor 7-like 2 isoform 1 [Homo sapiens] 658 0.0
gi|226371627 transcription factor 7-like 2 isoform 6 [Homo sapiens] 600 e-172
gi|226371623 transcription factor 7-like 2 isoform 4 [Homo sapiens] 586 e-167
gi|226371620 transcription factor 7-like 2 isoform 3 [Homo sapiens] 582 e-166
gi|7705917 lymphoid enhancer-binding factor 1 isoform 1 [Homo sa... 397 e-110
gi|195222734 lymphoid enhancer-binding factor 1 isoform 3 [Homo ... 360 2e-99
gi|195222732 lymphoid enhancer-binding factor 1 isoform 2 [Homo ... 360 2e-99
gi|42518080 transcription factor 7 (T-cell specific, HMG-box) is... 262 7e-70
gi|198442849 transcription factor 7 (T-cell specific, HMG-box) 5... 236 6e-62
gi|42518078 transcription factor 7 (T-cell specific, HMG-box) is... 210 3e-54
gi|47419938 transcription factor 7 (T-cell specific, HMG-box) is... 210 3e-54
gi|42518074 transcription factor 7 (T-cell specific, HMG-box) is... 209 4e-54
gi|198442851 transcription factor 7 (T-cell specific, HMG-box) 6... 209 6e-54
gi|42714657 transcription factor 7 (T-cell specific, HMG-box) is... 209 6e-54
gi|4557853 transcription factor SOX9 [Homo sapiens] 73 8e-13
gi|112421108 capicua homolog [Homo sapiens] 67 6e-11
gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Hom... 66 8e-11
gi|41406089 SRY-box 13 [Homo sapiens] 66 1e-10
gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Hom... 65 1e-10
gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Hom... 65 1e-10
gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo... 65 1e-10
gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo... 65 1e-10
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 65 1e-10
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 65 1e-10
gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens] 65 1e-10
gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo... 62 1e-09
gi|5902108 SRY-box 21 [Homo sapiens] 61 3e-09
>gi|13786123 HMG-box transcription factor TCF-3 [Homo sapiens]
Length = 588
Score = 1197 bits (3096), Expect = 0.0
Identities = 588/588 (100%), Positives = 588/588 (100%)
Query: 1 MPQLGGGGGGGGGGSGGGGGSSAGAAGGGDDLGANDELIPFQDEGGEEQEPSSDSASAQR 60
MPQLGGGGGGGGGGSGGGGGSSAGAAGGGDDLGANDELIPFQDEGGEEQEPSSDSASAQR
Sbjct: 1 MPQLGGGGGGGGGGSGGGGGSSAGAAGGGDDLGANDELIPFQDEGGEEQEPSSDSASAQR 60
Query: 61 DLDEVKSSLVNESENQSSSSDSEAERRPQPVRDTFQKPRDYFAEVRRPQDSAFFKGPPYP 120
DLDEVKSSLVNESENQSSSSDSEAERRPQPVRDTFQKPRDYFAEVRRPQDSAFFKGPPYP
Sbjct: 61 DLDEVKSSLVNESENQSSSSDSEAERRPQPVRDTFQKPRDYFAEVRRPQDSAFFKGPPYP 120
Query: 121 GYPFLMIPDLSSPYLSNGPLSPGGARTYLQMKWPLLDVPSSATVKDTRSPSPAHLSNKVP 180
GYPFLMIPDLSSPYLSNGPLSPGGARTYLQMKWPLLDVPSSATVKDTRSPSPAHLSNKVP
Sbjct: 121 GYPFLMIPDLSSPYLSNGPLSPGGARTYLQMKWPLLDVPSSATVKDTRSPSPAHLSNKVP 180
Query: 181 VVQHPHHMHPLTPLITYSNDHFSPGSPPTHLSPEIDPKTGIPRPPHPSELSPYYPLSPGA 240
VVQHPHHMHPLTPLITYSNDHFSPGSPPTHLSPEIDPKTGIPRPPHPSELSPYYPLSPGA
Sbjct: 181 VVQHPHHMHPLTPLITYSNDHFSPGSPPTHLSPEIDPKTGIPRPPHPSELSPYYPLSPGA 240
Query: 241 VGQIPHPLGWLVPQQGQPMYSLPPGGFRHPYPALAMNASMSSLVSSRFSPHMVAPAHPGL 300
VGQIPHPLGWLVPQQGQPMYSLPPGGFRHPYPALAMNASMSSLVSSRFSPHMVAPAHPGL
Sbjct: 241 VGQIPHPLGWLVPQQGQPMYSLPPGGFRHPYPALAMNASMSSLVSSRFSPHMVAPAHPGL 300
Query: 301 PTSGIPHPAIVSPIVKQEPAPPSLSPAVSVKSPVTVKKEEEKKPHVKKPLNAFMLYMKEM 360
PTSGIPHPAIVSPIVKQEPAPPSLSPAVSVKSPVTVKKEEEKKPHVKKPLNAFMLYMKEM
Sbjct: 301 PTSGIPHPAIVSPIVKQEPAPPSLSPAVSVKSPVTVKKEEEKKPHVKKPLNAFMLYMKEM 360
Query: 361 RAKVVAECTLKESAAINQILGRKWHNLSREEQAKYYELARKERQLHSQLYPTWSARDNYG 420
RAKVVAECTLKESAAINQILGRKWHNLSREEQAKYYELARKERQLHSQLYPTWSARDNYG
Sbjct: 361 RAKVVAECTLKESAAINQILGRKWHNLSREEQAKYYELARKERQLHSQLYPTWSARDNYG 420
Query: 421 KKKKRKREKQLSQTQSQQQVQEAEGALASKSKKPCVQYLPPEKPCDSPASSHGSMLDSPA 480
KKKKRKREKQLSQTQSQQQVQEAEGALASKSKKPCVQYLPPEKPCDSPASSHGSMLDSPA
Sbjct: 421 KKKKRKREKQLSQTQSQQQVQEAEGALASKSKKPCVQYLPPEKPCDSPASSHGSMLDSPA 480
Query: 481 TPSAALASPAAPAATHSEQAQPLSLTTKPETRAQLALHSAAFLSAKAAASSSGQMGSQPP 540
TPSAALASPAAPAATHSEQAQPLSLTTKPETRAQLALHSAAFLSAKAAASSSGQMGSQPP
Sbjct: 481 TPSAALASPAAPAATHSEQAQPLSLTTKPETRAQLALHSAAFLSAKAAASSSGQMGSQPP 540
Query: 541 LLSRPLPLGSMPTALLASPPSFPATLHAHQALPVLQAQPLSLVTKSAH 588
LLSRPLPLGSMPTALLASPPSFPATLHAHQALPVLQAQPLSLVTKSAH
Sbjct: 541 LLSRPLPLGSMPTALLASPPSFPATLHAHQALPVLQAQPLSLVTKSAH 588
>gi|226371625 transcription factor 7-like 2 isoform 5 [Homo sapiens]
Length = 579
Score = 671 bits (1730), Expect = 0.0
Identities = 359/585 (61%), Positives = 426/585 (72%), Gaps = 39/585 (6%)
Query: 27 GGGDDLGANDELIPFQDEGGEEQEPSSDSASAQRDLDEVKSSLVNESE-NQSSSSDSEAE 85
GGGDDLGANDELI F+DEG E++E SS+++SA+RDL +VKSSLVNESE NQ+SSSDSEAE
Sbjct: 7 GGGDDLGANDELISFKDEG-EQEEKSSENSSAERDLADVKSSLVNESETNQNSSSDSEAE 65
Query: 86 RRPQPVRDTFQ-KPRDYFAEVRRPQDSAFFKGPPYPGYPFLMIPDLSSPYLSNGPLSPGG 144
RRP P ++F+ K R+ E + QD FKGPPYPGYPF+MIPDL+SPYL NG LSP
Sbjct: 66 RRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGSLSPT- 124
Query: 145 ARTYLQMKWPLLDVPSSA-----TVKDTRSPSPAHL-SNKVPVVQHPHHMHPLTPLITYS 198
ARTYLQMKWPLLDV + + +KD RSPSPAH+ SNKVPVVQHPHH+HPLTPLITYS
Sbjct: 125 ARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVVQHPHHVHPLTPLITYS 184
Query: 199 NDHFSPGSPPTHLSPEIDPKTGIPRPPHPSELSPYYPLSPGAVGQIPHPLGWLVPQQGQP 258
N+HF+PG+PP HL ++DPKTGIPRPPHP ++SPYYPLSPG VGQIPHPLGWLVPQQGQP
Sbjct: 185 NEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGWLVPQQGQP 244
Query: 259 MYSLPPGGFRHPYP-ALAMNASMSSLVSSRFSPHMVAPAHPGLPTSGIPHPAIVSPIVKQ 317
+Y + GGFRHPYP AL +NASMS RF PHMV P H L T+GIPHPAIV+P VKQ
Sbjct: 245 VYPITTGGFRHPYPTALTVNASMS-----RFPPHMVPPHHT-LHTTGIPHPAIVTPTVKQ 298
Query: 318 EPAPPSLSPAVSVKSPVTVKKEEEKKPHVKKPLNAFMLYMKEMRAKVVAECTLKESAAIN 377
E + + S K + K+EE+KKPH+KKPLNAFMLYMKEMRAKVVAECTLKESAAIN
Sbjct: 299 ESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAIN 358
Query: 378 QILGRKWHNLSREEQAKYYELARKERQLHSQLYPTWSARDNYGKKKKRKREKQLSQTQSQ 437
QILGR+WH LSREEQAKYYELARKERQLH QLYP WSARDNYGKKKKRKR+KQ +T
Sbjct: 359 QILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNDL 418
Query: 438 QQVQEAEGALA----------SKSKKPCVQYLPPEKPCDSPASSHGSMLDSPATPSAALA 487
++ + KK CV+Y+ E C SP SS GS+LDSP L
Sbjct: 419 SAPKKCRARFGLDQQNNWCGPCRRKKKCVRYIQGEGSCLSPPSSDGSLLDSPPPSPNLLG 478
Query: 488 SPAAPAATHSEQAQPLSLTTKPETRAQLAL--HSAAFLSAKAAASSSGQMGS----QPPL 541
SP A + +EQ QPLSL+ KP+ A L++ A L A+A +S + PP
Sbjct: 479 SPPRDAKSQTEQTQPLSLSLKPDPLAHLSMMPPPPALLLAEATHKASALCPNGALDLPPA 538
Query: 542 LSRPLPLGSMPTALLASPPSFPATLHAHQALPVLQAQPLSLVTKS 586
+P + P++ +A P + ++LH+H +L Q QPLSLVTKS
Sbjct: 539 ALQP----AAPSSSIAQPST--SSLHSHSSLAGTQPQPLSLVTKS 577
>gi|170014696 transcription factor 7-like 2 isoform 2 [Homo sapiens]
Length = 596
Score = 665 bits (1716), Expect = 0.0
Identities = 360/602 (59%), Positives = 427/602 (70%), Gaps = 56/602 (9%)
Query: 27 GGGDDLGANDELIPFQDEGGEEQEPSSDSASAQRDLDEVKSSLVNESE-NQSSSSDSEAE 85
GGGDDLGANDELI F+DEG E++E SS+++SA+RDL +VKSSLVNESE NQ+SSSDSEAE
Sbjct: 7 GGGDDLGANDELISFKDEG-EQEEKSSENSSAERDLADVKSSLVNESETNQNSSSDSEAE 65
Query: 86 RRPQPVRDTFQ-KPRDYFAEVRRPQDSAFFKGPPYPGYPFLMIPDLSSPYLSNGPLSPGG 144
RRP P ++F+ K R+ E + QD FKGPPYPGYPF+MIPDL+SPYL NG LSP
Sbjct: 66 RRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGSLSPT- 124
Query: 145 ARTYLQMKWPLLDVPSSA-----TVKDTRSPSPAHL-SNKVPVVQHPHHMHPLTPLITYS 198
ARTYLQMKWPLLDV + + +KD RSPSPAH+ SNKVPVVQHPHH+HPLTPLITYS
Sbjct: 125 ARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVVQHPHHVHPLTPLITYS 184
Query: 199 NDHFSPGSPPTHLSPEIDPKTGIPRPPHPSELSPYYPLSPGAVGQIPHPLGWLVPQQGQP 258
N+HF+PG+PP HL ++DPKTGIPRPPHP ++SPYYPLSPG VGQIPHPLGWLVPQQGQP
Sbjct: 185 NEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGWLVPQQGQP 244
Query: 259 MYSLPPGGFRHPYP-ALAMNASMSSLVSSRFSPHMVAPAHPGLPTSGIPHPAIVSPIVKQ 317
+Y + GGFRHPYP AL +NASMS RF PHMV P H L T+GIPHPAIV+P VKQ
Sbjct: 245 VYPITTGGFRHPYPTALTVNASMS-----RFPPHMVPPHHT-LHTTGIPHPAIVTPTVKQ 298
Query: 318 EPAPPSLSPAVSVKSPVTVKKEEEKKPHVKKPLNAFMLYMKEMRAKVVAECTLKESAAIN 377
E + + S K + K+EE+KKPH+KKPLNAFMLYMKEMRAKVVAECTLKESAAIN
Sbjct: 299 ESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAIN 358
Query: 378 QILGRKWHNLSREEQAKYYELARKERQLHSQLYPTWSARDNYGKKKKRKREKQLSQTQSQ 437
QILGR+WH LSREEQAKYYELARKERQLH QLYP WSARDNYGKKKKRKR+KQ +T
Sbjct: 359 QILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNEH 418
Query: 438 QQV---------------------------QEAEGALASKSKKPCVQYLPPEKPCDSPAS 470
+ Q+ + KK CV+Y+ E C SP S
Sbjct: 419 SECFLNPCLSLPPITDLSAPKKCRARFGLDQQNNWCGPCRRKKKCVRYIQGEGSCLSPPS 478
Query: 471 SHGSMLDSPATPSAALASPAAPAATHSEQAQPLSLTTKPETRAQLAL--HSAAFLSAKAA 528
S GS+LDSP L SP A + +EQ QPLSL+ KP+ A L++ A L A+A
Sbjct: 479 SDGSLLDSPPPSPNLLGSPPRDAKSQTEQTQPLSLSLKPDPLAHLSMMPPPPALLLAEAT 538
Query: 529 ASSSGQMGS----QPPLLSRPLPLGSMPTALLASPPSFPATLHAHQALPVLQAQPLSLVT 584
+S + PP +P + P++ +A P + ++LH+H +L Q QPLSLVT
Sbjct: 539 HKASALCPNGALDLPPAALQP----AAPSSSIAQPST--SSLHSHSSLAGTQPQPLSLVT 592
Query: 585 KS 586
KS
Sbjct: 593 KS 594
>gi|226371764 transcription factor 7-like 2 isoform 1 [Homo sapiens]
Length = 602
Score = 658 bits (1697), Expect = 0.0
Identities = 359/608 (59%), Positives = 426/608 (70%), Gaps = 62/608 (10%)
Query: 27 GGGDDLGANDELIPFQDEGGEEQEPSSDSASAQRDLDEVKSSLVNESE-NQSSSSDSEAE 85
GGGDDLGANDELI F+DEG E++E SS+++SA+RDL +VKSSLVNESE NQ+SSSDSEAE
Sbjct: 7 GGGDDLGANDELISFKDEG-EQEEKSSENSSAERDLADVKSSLVNESETNQNSSSDSEAE 65
Query: 86 RRPQPVRDTFQ-KPRDYFAEVRRPQDSAFFKGPPYPGYPFLMIPDLSSPYLSNGPLSPGG 144
RRP P ++F+ K R+ E + QD FKGPPYPGYPF+MIPDL+SPYL NG LSP
Sbjct: 66 RRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGSLSPT- 124
Query: 145 ART-----------------------YLQMKWPLLDVPSSA-----TVKDTRSPSPAHL- 175
ART YLQMKWPLLDV + + +KD RSPSPAH+
Sbjct: 125 ARTLHFQSGSTHYSAYKTIEHQIAVQYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIV 184
Query: 176 SNKVPVVQHPHHMHPLTPLITYSNDHFSPGSPPTHLSPEIDPKTGIPRPPHPSELSPYYP 235
SNKVPVVQHPHH+HPLTPLITYSN+HF+PG+PP HL ++DPKTGIPRPPHP ++SPYYP
Sbjct: 185 SNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYP 244
Query: 236 LSPGAVGQIPHPLGWLVPQQGQPMYSLPPGGFRHPYP-ALAMNASMSSLVSSRFSPHMVA 294
LSPG VGQIPHPLGWLVPQQGQP+Y + GGFRHPYP AL +NASMS RF PHMV
Sbjct: 245 LSPGTVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMS-----RFPPHMVP 299
Query: 295 PAHPGLPTSGIPHPAIVSPIVKQEPAPPSLSPAVSVKSPVTVKKEEEKKPHVKKPLNAFM 354
P H L T+GIPHPAIV+P VKQE + + S K + K+EE+KKPH+KKPLNAFM
Sbjct: 300 PHHT-LHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFM 358
Query: 355 LYMKEMRAKVVAECTLKESAAINQILGRKWHNLSREEQAKYYELARKERQLHSQLYPTWS 414
LYMKEMRAKVVAECTLKESAAINQILGR+WH LSREEQAKYYELARKERQLH QLYP WS
Sbjct: 359 LYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWS 418
Query: 415 ARDNYGKKKKRKREKQLSQTQSQQQVQEAEGALA----------SKSKKPCVQYLPPEKP 464
ARDNYGKKKKRKR+KQ +T ++ + KK CV+Y+ E
Sbjct: 419 ARDNYGKKKKRKRDKQPGETNDANTPKKCRALFGLDRQTLWCKPCRRKKKCVRYIQGEGS 478
Query: 465 CDSPASSHGSMLDSPATPSAALASPAAPAATHSEQAQPLSLTTKPETRAQLAL--HSAAF 522
C SP SS GS+LDSP L SP A + +EQ QPLSL+ KP+ A L++ A
Sbjct: 479 CLSPPSSDGSLLDSPPPSPNLLGSPPRDAKSQTEQTQPLSLSLKPDPLAHLSMMPPPPAL 538
Query: 523 LSAKAAASSSGQMGS----QPPLLSRPLPLGSMPTALLASPPSFPATLHAHQALPVLQAQ 578
L A+A +S + PP +P + P++ +A P + ++LH+H +L Q Q
Sbjct: 539 LLAEATHKASALCPNGALDLPPAALQP----AAPSSSIAQPST--SSLHSHSSLAGTQPQ 592
Query: 579 PLSLVTKS 586
PLSLVTKS
Sbjct: 593 PLSLVTKS 600
>gi|226371627 transcription factor 7-like 2 isoform 6 [Homo sapiens]
Length = 442
Score = 600 bits (1548), Expect = e-172
Identities = 302/422 (71%), Positives = 347/422 (82%), Gaps = 17/422 (4%)
Query: 27 GGGDDLGANDELIPFQDEGGEEQEPSSDSASAQRDLDEVKSSLVNESE-NQSSSSDSEAE 85
GGGDDLGANDELI F+DEG E++E SS+++SA+RDL +VKSSLVNESE NQ+SSSDSEAE
Sbjct: 7 GGGDDLGANDELISFKDEG-EQEEKSSENSSAERDLADVKSSLVNESETNQNSSSDSEAE 65
Query: 86 RRPQPVRDTFQ-KPRDYFAEVRRPQDSAFFKGPPYPGYPFLMIPDLSSPYLSNGPLSPGG 144
RRP P ++F+ K R+ E + QD FKGPPYPGYPF+MIPDL+SPYL NG LSP
Sbjct: 66 RRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGSLSPT- 124
Query: 145 ARTYLQMKWPLLDVPSSA-----TVKDTRSPSPAHL-SNKVPVVQHPHHMHPLTPLITYS 198
ARTYLQMKWPLLDV + + +KD RSPSPAH+ SNKVPVVQHPHH+HPLTPLITYS
Sbjct: 125 ARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVVQHPHHVHPLTPLITYS 184
Query: 199 NDHFSPGSPPTHLSPEIDPKTGIPRPPHPSELSPYYPLSPGAVGQIPHPLGWLVPQQGQP 258
N+HF+PG+PP HL ++DPKTGIPRPPHP ++SPYYPLSPG VGQIPHPLGWLVPQQGQP
Sbjct: 185 NEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGWLVPQQGQP 244
Query: 259 MYSLPPGGFRHPYP-ALAMNASMSSLVSSRFSPHMVAPAHPGLPTSGIPHPAIVSPIVKQ 317
+Y + GGFRHPYP AL +NASMS RF PHMV P H L T+GIPHPAIV+P VKQ
Sbjct: 245 VYPITTGGFRHPYPTALTVNASMS-----RFPPHMVPPHHT-LHTTGIPHPAIVTPTVKQ 298
Query: 318 EPAPPSLSPAVSVKSPVTVKKEEEKKPHVKKPLNAFMLYMKEMRAKVVAECTLKESAAIN 377
E + + S K + K+EE+KKPH+KKPLNAFMLYMKEMRAKVVAECTLKESAAIN
Sbjct: 299 ESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAIN 358
Query: 378 QILGRKWHNLSREEQAKYYELARKERQLHSQLYPTWSARDNYGKKKKRKREKQLSQTQSQ 437
QILGR+WH LSREEQAKYYELARKERQLH QLYP WSARDNYGKKKKRKR+KQ +T +
Sbjct: 359 QILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNGE 418
Query: 438 QQ 439
++
Sbjct: 419 KK 420
>gi|226371623 transcription factor 7-like 2 isoform 4 [Homo sapiens]
Length = 455
Score = 586 bits (1511), Expect = e-167
Identities = 298/422 (70%), Positives = 341/422 (80%), Gaps = 21/422 (4%)
Query: 27 GGGDDLGANDELIPFQDEGGEEQEPSSDSASAQRDLDEVKSSLVNESE-NQSSSSDSEAE 85
GGGDDLGANDELI F+DEG E++E SS+++SA+RDL +VKSSLVNESE NQ+SSSDSEAE
Sbjct: 7 GGGDDLGANDELISFKDEG-EQEEKSSENSSAERDLADVKSSLVNESETNQNSSSDSEAE 65
Query: 86 RRPQPVRDTFQ-KPRDYFAEVRRPQDSAFFKGPPYPGYPFLMIPDLSSPYLSNGPLSPGG 144
RRP P ++F+ K R+ E + QD FKGPPYPGYPF+MIPDL+SPYL NG LSP
Sbjct: 66 RRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGSLSPT- 124
Query: 145 ARTYLQMKWPLLDVPSSA-----TVKDTRSPSPAHL-SNKVPVVQHPHHMHPLTPLITYS 198
ARTYLQMKWPLLDV + + +KD RSPSPAH+ SNKVPVVQHPHH+HPLTPLITYS
Sbjct: 125 ARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVVQHPHHVHPLTPLITYS 184
Query: 199 NDHFSPGSPPTHLSPEIDPKTGIPRPPHPSELSPYYPLSPGAVGQIPHPLGWLVPQQGQP 258
N+HF+PG+PP HL ++DPKTGIPRPPHP ++SPYYPLSPG VGQIPHPLGW QGQP
Sbjct: 185 NEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGW----QGQP 240
Query: 259 MYSLPPGGFRHPYP-ALAMNASMSSLVSSRFSPHMVAPAHPGLPTSGIPHPAIVSPIVKQ 317
+Y + GGFRHPYP AL +NASMS RF PHMV P H L T+GIPHPAIV+P VKQ
Sbjct: 241 VYPITTGGFRHPYPTALTVNASMS-----RFPPHMVPPHHT-LHTTGIPHPAIVTPTVKQ 294
Query: 318 EPAPPSLSPAVSVKSPVTVKKEEEKKPHVKKPLNAFMLYMKEMRAKVVAECTLKESAAIN 377
E + + S K + K+EE+KKPH+KKPLNAFMLYMKEMRAKVVAECTLKESAAIN
Sbjct: 295 ESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAIN 354
Query: 378 QILGRKWHNLSREEQAKYYELARKERQLHSQLYPTWSARDNYGKKKKRKREKQLSQTQSQ 437
QILGR+WH LSREEQAKYYELARKERQLH QLYP WSARDNYGKKKKRKR+KQ +T
Sbjct: 355 QILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNEH 414
Query: 438 QQ 439
+
Sbjct: 415 SE 416
>gi|226371620 transcription factor 7-like 2 isoform 3 [Homo sapiens]
Length = 489
Score = 582 bits (1501), Expect = e-166
Identities = 303/469 (64%), Positives = 346/469 (73%), Gaps = 64/469 (13%)
Query: 27 GGGDDLGANDELIPFQDEGGEEQEPSSDSASAQRDLDEVKSSLVNESE-NQSSSSDSEAE 85
GGGDDLGANDELI F+DEG E++E SS+++SA+RDL +VKSSLVNESE NQ+SSSDSEAE
Sbjct: 7 GGGDDLGANDELISFKDEG-EQEEKSSENSSAERDLADVKSSLVNESETNQNSSSDSEAE 65
Query: 86 RRPQPVRDTFQ-KPRDYFAEVRRPQDSAFFKGPPYPGYPFLMIPDLSSPYLSNGPLSPGG 144
RRP P ++F+ K R+ E + QD FKGPPYPGYPF+MIPDL+SPYL NG LSP
Sbjct: 66 RRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGSLSP-T 124
Query: 145 ARTYLQMKWPLLDV-----PSSATVKDTRSPSPAHL------------------------ 175
ARTYLQMKWPLLDV S +KD RSPSPAH+
Sbjct: 125 ARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSPLPCCTQGHDCQHFYPPSDFTV 184
Query: 176 ------------------------SNKVPVVQHPHHMHPLTPLITYSNDHFSPGSPPTHL 211
SNKVPVVQHPHH+HPLTPLITYSN+HF+PG+PP HL
Sbjct: 185 STQVFRDMKRSHSLQKVGEPWCIESNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHL 244
Query: 212 SPEIDPKTGIPRPPHPSELSPYYPLSPGAVGQIPHPLGWLVPQQGQPMYSLPPGGFRHPY 271
++DPKTGIPRPPHP ++SPYYPLSPG VGQIPHPLGWLVPQQGQP+Y + GGFRHPY
Sbjct: 245 PADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGWLVPQQGQPVYPITTGGFRHPY 304
Query: 272 P-ALAMNASMSSLVSSRFSPHMVAPAHPGLPTSGIPHPAIVSPIVKQEPAPPSLSPAVSV 330
P AL +NASM SRF PHMV P H L T+GIPHPAIV+P VKQE + + S
Sbjct: 305 PTALTVNASM-----SRFPPHMVPPHHT-LHTTGIPHPAIVTPTVKQESSQSDVGSLHSS 358
Query: 331 KSPVTVKKEEEKKPHVKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRKWHNLSRE 390
K + K+EE+KKPH+KKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGR+WH LSRE
Sbjct: 359 KHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSRE 418
Query: 391 EQAKYYELARKERQLHSQLYPTWSARDNYGKKKKRKREKQLSQTQSQQQ 439
EQAKYYELARKERQLH QLYP WSARDNYGKKKKRKR+KQ +T +++
Sbjct: 419 EQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNGEKK 467
>gi|7705917 lymphoid enhancer-binding factor 1 isoform 1 [Homo
sapiens]
Length = 399
Score = 397 bits (1019), Expect = e-110
Identities = 230/437 (52%), Positives = 285/437 (65%), Gaps = 63/437 (14%)
Query: 1 MPQLGGGGGGGGGGSGGGGGSSAGAAGGGDDLGANDELIPFQDEGGEEQEPSSDSAS--- 57
MPQL GGGGGGGG +L A DE+IPF+DEG ++E S
Sbjct: 1 MPQLSGGGGGGGGDP---------------ELCATDEMIPFKDEGDPQKEKIFAEISHPE 45
Query: 58 AQRDLDEVKSSLVNESENQSSSSDSEAERRPQPVRDTFQ-KPRDYFAEVRRPQDSAFFKG 116
+ DL ++KSSLVNESE +S+ E R+ Q ++ + K R++ + + P + KG
Sbjct: 46 EEGDLADIKSSLVNESEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKG 105
Query: 117 PPYPGYP-FLMIPDLSS-PYLSNGPLSPGGARTYLQMKWPLLDVPSSATVKDTRSPSPAH 174
P Y Y ++M+P++++ PY+SNG LSP RT
Sbjct: 106 PSYSSYSGYIMMPNMNNDPYMSNGSLSPPIPRT--------------------------- 138
Query: 175 LSNKVPVVQHPHHMHPLTPLITYSNDHFSPGSPPTHLSPEIDPKTGIPRPPHPSELSPYY 234
SNKVPVVQ H +HPLTPLITYS++HFSPGS P+H+ +++ K G+ R P ++ +Y
Sbjct: 139 -SNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFY 197
Query: 235 PLSPGAVGQIPHPLGWLVPQQGQPMYSLPPGGFRHPYPA-LAMNASMSSLVSSRFSPHMV 293
PLSPG VGQI PLGW QGQP+Y + GGFR PYP+ L+++ SMS RFS HM+
Sbjct: 198 PLSPGGVGQITPPLGW----QGQPVYPIT-GGFRQPYPSSLSVDTSMS-----RFSHHMI 247
Query: 294 APAHPGLPTSGIPHPAIVSPIVKQEPAPPSLSPAVSVKSPVTVKKEEE-KKPHVKKPLNA 352
P PG T+GIPHPAIV+P VKQE P + S + VK +KE+E K+PH+KKPLNA
Sbjct: 248 -PGPPGPHTTGIPHPAIVTPQVKQEH-PHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNA 305
Query: 353 FMLYMKEMRAKVVAECTLKESAAINQILGRKWHNLSREEQAKYYELARKERQLHSQLYPT 412
FMLYMKEMRA VVAECTLKESAAINQILGR+WH LSREEQAKYYELARKERQLH QLYP
Sbjct: 306 FMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPG 365
Query: 413 WSARDNYGKKKKRKREK 429
WSARDNYGKKKKRKREK
Sbjct: 366 WSARDNYGKKKKRKREK 382
>gi|195222734 lymphoid enhancer-binding factor 1 isoform 3 [Homo
sapiens]
Length = 386
Score = 360 bits (925), Expect = 2e-99
Identities = 213/436 (48%), Positives = 262/436 (60%), Gaps = 89/436 (20%)
Query: 1 MPQLGGGGGGGGGGSGGGGGSSAGAAGGGDDLGANDELIPFQDEGGEEQEPSSDSAS--- 57
MPQL GGGGGGGG +L A DE+IPF+DEG ++E S
Sbjct: 1 MPQLSGGGGGGGGDP---------------ELCATDEMIPFKDEGDPQKEKIFAEISHPE 45
Query: 58 AQRDLDEVKSSLVNESENQSSSSDSEAERRPQPVRDTFQ-KPRDYFAEVRRPQDSAFFKG 116
+ DL ++KSSLVNESE +S+ E R+ Q ++ + K R++ + + P + KG
Sbjct: 46 EEGDLADIKSSLVNESEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKG 105
Query: 117 PPYPGYP-FLMIPDLSS-PYLSNGPLSPGGARTYLQMKWPLLDVPSSATVKDTRSPSPAH 174
P Y Y ++M+P++++ PY+SNG LSP RT
Sbjct: 106 PSYSSYSGYIMMPNMNNDPYMSNGSLSPPIPRT--------------------------- 138
Query: 175 LSNKVPVVQHPHHMHPLTPLITYSNDHFSPGSPPTHLSPEIDPKTGIPRPPHPSELSPYY 234
SNKVPVVQ H +HPLTPLITYS++HFSPGS P+H+ +++ K G+ R P ++ +Y
Sbjct: 139 -SNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFY 197
Query: 235 PLSPGAVGQIPHPLGWLVPQQGQPMYSLPPGGFRHPYPALAMNASMSSLVSSRFSPHMVA 294
PLSPG VGQI PLGW FS HM+
Sbjct: 198 PLSPGGVGQITPPLGW-------------------------------------FSHHMI- 219
Query: 295 PAHPGLPTSGIPHPAIVSPIVKQEPAPPSLSPAVSVKSPVTVKKEEE-KKPHVKKPLNAF 353
P PG T+GIPHPAIV+P VKQE P + S + VK +KE+E K+PH+KKPLNAF
Sbjct: 220 PGPPGPHTTGIPHPAIVTPQVKQEH-PHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAF 278
Query: 354 MLYMKEMRAKVVAECTLKESAAINQILGRKWHNLSREEQAKYYELARKERQLHSQLYPTW 413
MLYMKEMRA VVAECTLKESAAINQILGR+WH LSREEQAKYYELARKERQLH QLYP W
Sbjct: 279 MLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGW 338
Query: 414 SARDNYGKKKKRKREK 429
SARDNYGKKKKRKREK
Sbjct: 339 SARDNYGKKKKRKREK 354
>gi|195222732 lymphoid enhancer-binding factor 1 isoform 2 [Homo
sapiens]
Length = 371
Score = 360 bits (925), Expect = 2e-99
Identities = 213/436 (48%), Positives = 262/436 (60%), Gaps = 89/436 (20%)
Query: 1 MPQLGGGGGGGGGGSGGGGGSSAGAAGGGDDLGANDELIPFQDEGGEEQEPSSDSAS--- 57
MPQL GGGGGGGG +L A DE+IPF+DEG ++E S
Sbjct: 1 MPQLSGGGGGGGGDP---------------ELCATDEMIPFKDEGDPQKEKIFAEISHPE 45
Query: 58 AQRDLDEVKSSLVNESENQSSSSDSEAERRPQPVRDTFQ-KPRDYFAEVRRPQDSAFFKG 116
+ DL ++KSSLVNESE +S+ E R+ Q ++ + K R++ + + P + KG
Sbjct: 46 EEGDLADIKSSLVNESEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKG 105
Query: 117 PPYPGYP-FLMIPDLSS-PYLSNGPLSPGGARTYLQMKWPLLDVPSSATVKDTRSPSPAH 174
P Y Y ++M+P++++ PY+SNG LSP RT
Sbjct: 106 PSYSSYSGYIMMPNMNNDPYMSNGSLSPPIPRT--------------------------- 138
Query: 175 LSNKVPVVQHPHHMHPLTPLITYSNDHFSPGSPPTHLSPEIDPKTGIPRPPHPSELSPYY 234
SNKVPVVQ H +HPLTPLITYS++HFSPGS P+H+ +++ K G+ R P ++ +Y
Sbjct: 139 -SNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFY 197
Query: 235 PLSPGAVGQIPHPLGWLVPQQGQPMYSLPPGGFRHPYPALAMNASMSSLVSSRFSPHMVA 294
PLSPG VGQI PLGW FS HM+
Sbjct: 198 PLSPGGVGQITPPLGW-------------------------------------FSHHMI- 219
Query: 295 PAHPGLPTSGIPHPAIVSPIVKQEPAPPSLSPAVSVKSPVTVKKEEE-KKPHVKKPLNAF 353
P PG T+GIPHPAIV+P VKQE P + S + VK +KE+E K+PH+KKPLNAF
Sbjct: 220 PGPPGPHTTGIPHPAIVTPQVKQEH-PHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAF 278
Query: 354 MLYMKEMRAKVVAECTLKESAAINQILGRKWHNLSREEQAKYYELARKERQLHSQLYPTW 413
MLYMKEMRA VVAECTLKESAAINQILGR+WH LSREEQAKYYELARKERQLH QLYP W
Sbjct: 279 MLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGW 338
Query: 414 SARDNYGKKKKRKREK 429
SARDNYGKKKKRKREK
Sbjct: 339 SARDNYGKKKKRKREK 354
>gi|42518080 transcription factor 7 (T-cell specific, HMG-box)
isoform 1 [Homo sapiens]
Length = 384
Score = 262 bits (669), Expect = 7e-70
Identities = 189/479 (39%), Positives = 241/479 (50%), Gaps = 118/479 (24%)
Query: 1 MPQLGGGGGGGGGGSGGGGGSSAGAAGGGDDLGANDELIPFQDEGGEEQEPSSDSASA-Q 59
MPQL GGGG AGGGDDLGA DEL+ FQDEG E+ + S DSA+ +
Sbjct: 1 MPQLDSGGGG---------------AGGGDDLGAPDELLAFQDEGEEQDDKSRDSAAGPE 45
Query: 60 RDLDEVKSSLVNESENQSSSS--------------DSEAERRPQPVRDTF--QKPRDYFA 103
RDL E+KSSLVNESE + + ++EA R + F + P
Sbjct: 46 RDLAELKSSLVNESEGAAGGAGIPGVPGAGAGARGEAEALGREHAAQRLFPDKLPEPLED 105
Query: 104 EVRRPQ-DSAFFKGPPYPGYPFLMIPDLSSPYLSNGPLSPGGARTYLQMKWPLLDVPSSA 162
++ P+ S +K Y + LM +P P S
Sbjct: 106 GLKAPECTSGMYKETVYSAFNLLM-------------------------HYP----PPSG 136
Query: 163 TVKDTRSPSPAHLSNKVPVVQHPHHMHPLTPLITYSNDHFSPGSP-PTHLSPEIDPKTGI 221
+ + P H +N+ P H + L Y +HF+ SP PT +I K +
Sbjct: 137 AGQHPQPQPPLHKANQPP--------HGVPQLSLY--EHFN--SPHPTPAPADISQKQ-V 183
Query: 222 PRPPHPSELSPYYPLSPGAVGQIPHPLGWLVPQQGQPMYSLPPGGFRHPYPALAMNASMS 281
RP +LS +Y L+ G++GQ+PH + W +P+L + + +
Sbjct: 184 HRPLQTPDLSGFYSLTSGSMGQLPHTVSWFT------------------HPSLMLGSGV- 224
Query: 282 SLVSSRFSPHMVAPAHPGLPTSGIPHPAIVSPIVKQEPAPPSLSPAVSVKSPVTVKKEEE 341
P HP + IPHPAIV P KQE P + +S ++E
Sbjct: 225 -------------PGHP----AAIPHPAIVPPSGKQELQPFDRNLKTQAESKA---EKEA 264
Query: 342 KKPHVKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRKWHNLSREEQAKYYELARK 401
KKP +KKPLNAFMLYMKEMRAKV+AECTLKESAAINQILGR+WH LSREEQAKYYELARK
Sbjct: 265 KKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARK 324
Query: 402 ERQLHSQLYPTWSARDNYGKKKKRKREKQLSQTQSQQQVQEAEGALASKSKKPCVQYLP 460
ERQLH QLYP WSARDNYGKKK+R REK T + + A G K+ P +LP
Sbjct: 325 ERQLHMQLYPGWSARDNYGKKKRRSREKHQESTTGGK--RNAFGTYPEKAAAP-APFLP 380
>gi|198442849 transcription factor 7 (T-cell specific, HMG-box) 5
[Homo sapiens]
Length = 366
Score = 236 bits (601), Expect = 6e-62
Identities = 155/375 (41%), Positives = 193/375 (51%), Gaps = 78/375 (20%)
Query: 159 PSSATVKDTRSPSPAHLSNKVPVVQHPHHMHPLTPLITYSNDHFSPGSP-PTHLSPEIDP 217
P S + + P H +N+ P H + L Y +HF+ SP PT +I
Sbjct: 18 PPSGAGQHPQPQPPLHKANQPP--------HGVPQLSLY--EHFN--SPHPTPAPADISQ 65
Query: 218 KTGIPRPPHPSELSPYYPLSPGAVGQIPHPLGWLVPQQGQPMYSLPPGGFRHPYPALAMN 277
K + RP +LS +Y L+ G++GQ+PH + W +P+L +
Sbjct: 66 KQ-VHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFT------------------HPSLMLG 106
Query: 278 ASMSSLVSSRFSPHMVAPAHPGLPTSGIPHPAIVSPIVKQEPAPPSLSPAVSVKSPVTVK 337
+ + P HP + IPHPAIV P KQE P + +S
Sbjct: 107 SGV--------------PGHP----AAIPHPAIVPPSGKQELQPFDRNLKTQAESKA--- 145
Query: 338 KEEEKKPHVKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRKWHNLSREEQAKYYE 397
++E KKP +KKPLNAFMLYMKEMRAKV+AECTLKESAAINQILGR+WH LSREEQAKYYE
Sbjct: 146 EKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYE 205
Query: 398 LARKERQLHSQLYPTWSARDNYGKKKKRKREKQLSQTQSQQQV----------QEAEGAL 447
LARKERQLH QLYP WSARDNYGKKK+R REK T Q+ +
Sbjct: 206 LARKERQLHMQLYPGWSARDNYGKKKRRSREKHQESTTDPGSPKKCRARFGLNQQTDWCG 265
Query: 448 ASKSKKPCVQYLPPEKPCDSPASSHGSMLDSPAT---------------PSAALASPAAP 492
+ KK C++YLP E C SP S S L P + P+ L SPA P
Sbjct: 266 PCRRKKKCIRYLPGEGRCPSPVPSDDSALGCPGSPAPQDSPSYHLLPRFPTELLTSPAEP 325
Query: 493 AATHSEQAQPLSLTT 507
A T + LSL T
Sbjct: 326 APTSPGLSTALSLPT 340
>gi|42518078 transcription factor 7 (T-cell specific, HMG-box)
isoform 2 [Homo sapiens]
Length = 269
Score = 210 bits (535), Expect = 3e-54
Identities = 134/303 (44%), Positives = 168/303 (55%), Gaps = 56/303 (18%)
Query: 159 PSSATVKDTRSPSPAHLSNKVPVVQHPHHMHPLTPLITYSNDHFSPGSP-PTHLSPEIDP 217
P S + + P H +N+ P H + L Y +HF+ SP PT +I
Sbjct: 18 PPSGAGQHPQPQPPLHKANQPP--------HGVPQLSLY--EHFN--SPHPTPAPADISQ 65
Query: 218 KTGIPRPPHPSELSPYYPLSPGAVGQIPHPLGWLVPQQGQPMYSLPPGGFRHPYPALAMN 277
K + RP +LS +Y L+ G++GQ+PH + W +P+L +
Sbjct: 66 KQ-VHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFT------------------HPSLMLG 106
Query: 278 ASMSSLVSSRFSPHMVAPAHPGLPTSGIPHPAIVSPIVKQEPAPPSLSPAVSVKSPVTVK 337
+ + P HP + IPHPAIV P KQE P + +S
Sbjct: 107 SGV--------------PGHP----AAIPHPAIVPPSGKQELQPFDRNLKTQAESKA--- 145
Query: 338 KEEEKKPHVKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRKWHNLSREEQAKYYE 397
++E KKP +KKPLNAFMLYMKEMRAKV+AECTLKESAAINQILGR+WH LSREEQAKYYE
Sbjct: 146 EKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYE 205
Query: 398 LARKERQLHSQLYPTWSARDNYGKKKKRKREKQLSQTQSQQQVQEAEGALASKSKKPCVQ 457
LARKERQLH QLYP WSARDNYGKKK+R REK T + + A G K+ P
Sbjct: 206 LARKERQLHMQLYPGWSARDNYGKKKRRSREKHQESTTGGK--RNAFGTYPEKAAAP-AP 262
Query: 458 YLP 460
+LP
Sbjct: 263 FLP 265
>gi|47419938 transcription factor 7 (T-cell specific, HMG-box)
isoform 2 [Homo sapiens]
Length = 269
Score = 210 bits (535), Expect = 3e-54
Identities = 134/303 (44%), Positives = 168/303 (55%), Gaps = 56/303 (18%)
Query: 159 PSSATVKDTRSPSPAHLSNKVPVVQHPHHMHPLTPLITYSNDHFSPGSP-PTHLSPEIDP 217
P S + + P H +N+ P H + L Y +HF+ SP PT +I
Sbjct: 18 PPSGAGQHPQPQPPLHKANQPP--------HGVPQLSLY--EHFN--SPHPTPAPADISQ 65
Query: 218 KTGIPRPPHPSELSPYYPLSPGAVGQIPHPLGWLVPQQGQPMYSLPPGGFRHPYPALAMN 277
K + RP +LS +Y L+ G++GQ+PH + W +P+L +
Sbjct: 66 KQ-VHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFT------------------HPSLMLG 106
Query: 278 ASMSSLVSSRFSPHMVAPAHPGLPTSGIPHPAIVSPIVKQEPAPPSLSPAVSVKSPVTVK 337
+ + P HP + IPHPAIV P KQE P + +S
Sbjct: 107 SGV--------------PGHP----AAIPHPAIVPPSGKQELQPFDRNLKTQAESKA--- 145
Query: 338 KEEEKKPHVKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRKWHNLSREEQAKYYE 397
++E KKP +KKPLNAFMLYMKEMRAKV+AECTLKESAAINQILGR+WH LSREEQAKYYE
Sbjct: 146 EKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYE 205
Query: 398 LARKERQLHSQLYPTWSARDNYGKKKKRKREKQLSQTQSQQQVQEAEGALASKSKKPCVQ 457
LARKERQLH QLYP WSARDNYGKKK+R REK T + + A G K+ P
Sbjct: 206 LARKERQLHMQLYPGWSARDNYGKKKRRSREKHQESTTGGK--RNAFGTYPEKAAAP-AP 262
Query: 458 YLP 460
+LP
Sbjct: 263 FLP 265
>gi|42518074 transcription factor 7 (T-cell specific, HMG-box)
isoform 3 [Homo sapiens]
Length = 269
Score = 209 bits (533), Expect = 4e-54
Identities = 130/294 (44%), Positives = 163/294 (55%), Gaps = 53/294 (18%)
Query: 159 PSSATVKDTRSPSPAHLSNKVPVVQHPHHMHPLTPLITYSNDHFSPGSP-PTHLSPEIDP 217
P S + + P H +N+ P H + L Y +HF+ SP PT +I
Sbjct: 18 PPSGAGQHPQPQPPLHKANQPP--------HGVPQLSLY--EHFN--SPHPTPAPADISQ 65
Query: 218 KTGIPRPPHPSELSPYYPLSPGAVGQIPHPLGWLVPQQGQPMYSLPPGGFRHPYPALAMN 277
K + RP +LS +Y L+ G++GQ+PH + W +P+L +
Sbjct: 66 KQ-VHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFT------------------HPSLMLG 106
Query: 278 ASMSSLVSSRFSPHMVAPAHPGLPTSGIPHPAIVSPIVKQEPAPPSLSPAVSVKSPVTVK 337
+ + P HP + IPHPAIV P KQE P + +S
Sbjct: 107 SGV--------------PGHP----AAIPHPAIVPPSGKQELQPFDRNLKTQAESKA--- 145
Query: 338 KEEEKKPHVKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRKWHNLSREEQAKYYE 397
++E KKP +KKPLNAFMLYMKEMRAKV+AECTLKESAAINQILGR+WH LSREEQAKYYE
Sbjct: 146 EKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYE 205
Query: 398 LARKERQLHSQLYPTWSARDNYGKKKKRKREKQLSQTQSQQQVQEAEGALASKS 451
LARKERQLH QLYP WSARDNYGKKK+R REK T +E + +S
Sbjct: 206 LARKERQLHMQLYPGWSARDNYGKKKRRSREKHQESTTETNWPRELKDGNGQES 259
>gi|198442851 transcription factor 7 (T-cell specific, HMG-box) 6
[Homo sapiens]
Length = 250
Score = 209 bits (532), Expect = 6e-54
Identities = 128/277 (46%), Positives = 158/277 (57%), Gaps = 53/277 (19%)
Query: 159 PSSATVKDTRSPSPAHLSNKVPVVQHPHHMHPLTPLITYSNDHFSPGSP-PTHLSPEIDP 217
P S + + P H +N+ P H + L Y +HF+ SP PT +I
Sbjct: 18 PPSGAGQHPQPQPPLHKANQPP--------HGVPQLSLY--EHFN--SPHPTPAPADISQ 65
Query: 218 KTGIPRPPHPSELSPYYPLSPGAVGQIPHPLGWLVPQQGQPMYSLPPGGFRHPYPALAMN 277
K + RP +LS +Y L+ G++GQ+PH + W +P+L +
Sbjct: 66 KQ-VHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFT------------------HPSLMLG 106
Query: 278 ASMSSLVSSRFSPHMVAPAHPGLPTSGIPHPAIVSPIVKQEPAPPSLSPAVSVKSPVTVK 337
+ + P HP + IPHPAIV P KQE P + +S
Sbjct: 107 SGV--------------PGHP----AAIPHPAIVPPSGKQELQPFDRNLKTQAESKA--- 145
Query: 338 KEEEKKPHVKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRKWHNLSREEQAKYYE 397
++E KKP +KKPLNAFMLYMKEMRAKV+AECTLKESAAINQILGR+WH LSREEQAKYYE
Sbjct: 146 EKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYE 205
Query: 398 LARKERQLHSQLYPTWSARDNYGKKKKRKREKQLSQT 434
LARKERQLH QLYP WSARDNYGKKK+R REK T
Sbjct: 206 LARKERQLHMQLYPGWSARDNYGKKKRRSREKHQEST 242
>gi|42714657 transcription factor 7 (T-cell specific, HMG-box)
isoform 4 [Homo sapiens]
Length = 268
Score = 209 bits (532), Expect = 6e-54
Identities = 128/277 (46%), Positives = 158/277 (57%), Gaps = 53/277 (19%)
Query: 159 PSSATVKDTRSPSPAHLSNKVPVVQHPHHMHPLTPLITYSNDHFSPGSP-PTHLSPEIDP 217
P S + + P H +N+ P H + L Y +HF+ SP PT +I
Sbjct: 18 PPSGAGQHPQPQPPLHKANQPP--------HGVPQLSLY--EHFN--SPHPTPAPADISQ 65
Query: 218 KTGIPRPPHPSELSPYYPLSPGAVGQIPHPLGWLVPQQGQPMYSLPPGGFRHPYPALAMN 277
K + RP +LS +Y L+ G++GQ+PH + W +P+L +
Sbjct: 66 KQ-VHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFT------------------HPSLMLG 106
Query: 278 ASMSSLVSSRFSPHMVAPAHPGLPTSGIPHPAIVSPIVKQEPAPPSLSPAVSVKSPVTVK 337
+ + P HP + IPHPAIV P KQE P + +S
Sbjct: 107 SGV--------------PGHP----AAIPHPAIVPPSGKQELQPFDRNLKTQAESKA--- 145
Query: 338 KEEEKKPHVKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRKWHNLSREEQAKYYE 397
++E KKP +KKPLNAFMLYMKEMRAKV+AECTLKESAAINQILGR+WH LSREEQAKYYE
Sbjct: 146 EKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYE 205
Query: 398 LARKERQLHSQLYPTWSARDNYGKKKKRKREKQLSQT 434
LARKERQLH QLYP WSARDNYGKKK+R REK T
Sbjct: 206 LARKERQLHMQLYPGWSARDNYGKKKRRSREKHQEST 242
>gi|4557853 transcription factor SOX9 [Homo sapiens]
Length = 509
Score = 72.8 bits (177), Expect = 8e-13
Identities = 57/234 (24%), Positives = 100/234 (42%), Gaps = 34/234 (14%)
Query: 330 VKSPVTVKKEEEKKPHVKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRKWHNLSR 389
V PV V + KPHVK+P+NAFM++ + R K+ + +A +++ LG+ W L+
Sbjct: 89 VPMPVRVNGSSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNE 148
Query: 390 EEQAKYYELARKERQLHSQLYPTWSARDNYGKKKKRKREKQLSQTQSQQQVQEAEGALAS 449
E+ + E A + R H + +P + K + +R K + Q++ + + ++
Sbjct: 149 SEKRPFVEEAERLRVQHKKDHPDY--------KYQPRRRKSVKNGQAEAEEATEQTHISP 200
Query: 450 KSKKPCVQYLPPEKPCDSPASSHG-SMLDSPATPSAALASPAAPAATHSEQAQPLSLTTK 508
+ +Q DSP SS G S + SP S P P T QP K
Sbjct: 201 NAIFKALQ-------ADSPHSSSGMSEVHSPGEHSGQSQGPPTPPTTPKTDVQPGKADLK 253
Query: 509 PETRAQLALHSAAFLSAKAAASSSGQMGSQPPLLSRPLPLGSMPTALLASPPSF 562
E R + G QPP+ R + +G + + ++++ +F
Sbjct: 254 REGR------------------PLPEGGRQPPIDFRDVDIGELSSDVISNIETF 289
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 66.6 bits (161), Expect = 6e-11
Identities = 69/264 (26%), Positives = 108/264 (40%), Gaps = 49/264 (18%)
Query: 219 TGIPRPPHPSELSPYYPLSPGAVGQIPHPLGWLVPQQGQPMY-----SLPPGGFRHPYPA 273
TG P P + P SPG PHPLG + +G P S PPG P
Sbjct: 89 TGSADPERPPGAT--CPESPGPGP--PHPLGVVESGKGPPPTTEEEASGPPG---EPRLD 141
Query: 274 LAMNASMSSLVSSRFSPHMVAPAHPGLPTSGIPHPAIVSPIVKQEPAPPSLSPAVSVKSP 333
+ S SP + P PG + + A P + S K
Sbjct: 142 SETESDHDDAFLSIMSPEIQLPLPPGKRRT------------QSLSALPKERDSSSEKDG 189
Query: 334 VTVKKEEEKKPHVKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRKWHNLSREEQA 393
+ K E K H+++P+NAFM++ K RA V +++ +++ILG W+ L +E+
Sbjct: 190 RSPNKRE--KDHIRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQ 247
Query: 394 KYYELARKERQLHSQLYPTWSARDNYGKKK---------------KRKREKQLSQT---- 434
KY++LA + ++ H + +P W + KK K RE+ +S+T
Sbjct: 248 KYHDLAFQVKEAHFKAHPDWKWCNKDRKKSSSEAKPTSLGLAGGHKETRERSMSETGTAA 307
Query: 435 ----QSQQQVQEAEGALASKSKKP 454
S+ A+ L+S +K P
Sbjct: 308 APGVSSELLSVAAQTLLSSDTKAP 331
Score = 33.9 bits (76), Expect = 0.43
Identities = 85/358 (23%), Positives = 122/358 (34%), Gaps = 49/358 (13%)
Query: 6 GGGGGGGGGSGGGGG------------SSAGAAGGGDDLGANDELIPFQDEGGEEQEPS- 52
GGG G G+G G G + G AGG + +P Q + P+
Sbjct: 787 GGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAP 846
Query: 53 SDSASAQRDLDEVKSSLVNESENQSSSSDSEAERRPQPVRDTFQKPRDYFAEVRRPQDSA 112
A+A S S++ A P P Q A + Q +
Sbjct: 847 GTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPS--APPPKAQSVS 904
Query: 113 FFKGPPYPG----YPFLMIPDLSSPYLSNGPLSPGGARTYLQMKWPLLDVPSSATVKDTR 168
+ PP G P ++ L++P +S + GGA L PL+ P S V++
Sbjct: 905 PVQAPPPGGSAQLLPGKVLVPLAAPSMS---VRGGGAGQPL----PLVSPPFSVPVQNGA 957
Query: 169 SPSPAHLSNKVPV-VQHPHHMHPLTPLITYSNDHFSPGSPPTHLSPEID----------P 217
P P+ + PV V P + P T P S I P
Sbjct: 958 QP-PSKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALP 1016
Query: 218 KTGIPRPPHPSELSPYYPLSPGAVGQIPHPLGWLVPQQGQPMYSLPPGGFRHPYPALAM- 276
P ++ Y P S A+G LG P QP+ S P LA
Sbjct: 1017 LGTSPASSQAGTVTSYGPTSSVALGFT--SLGPSGPAFVQPLLSAGQA------PLLAPG 1068
Query: 277 NASMSSLVSSRFSPHMVAPAHPGLPT--SGIPHPAIVSPIVKQEPAPPSLSPAVSVKS 332
+S + S + P AP P + SG P P +P+ + APPSL V+ +
Sbjct: 1069 QVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATST 1126
>gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Homo
sapiens]
Length = 753
Score = 66.2 bits (160), Expect = 8e-11
Identities = 62/288 (21%), Positives = 115/288 (39%), Gaps = 17/288 (5%)
Query: 309 AIVSPIVKQEPAPPSLSPAVSVKSPVTVKKEEEKKPHVKKPLNAFMLYMKEMRAKVVAEC 368
+++ P VK E L+ S +++ HVK+P+NAFM++ + R +
Sbjct: 300 SLLEPSVKIETKDVPLTVLPSDAGIPDTPFSKDRNGHVKRPMNAFMVWARIHRPALAKAN 359
Query: 369 TLKESAAINQILGRKWHNLSREEQAKYYELARKERQLHSQLYPTWSARDNYGKKKKRKRE 428
+A I+ LG +W+ LS E++ YY+ A+K ++ H + +P W + GK+K+
Sbjct: 360 PAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKEKHREEFPGWVYQPRPGKRKRFPLS 419
Query: 429 KQLSQTQSQQQVQEAEGALASKSKKPCVQYLPP--EKPCDSPA--SSHGSMLDSPATPSA 484
+ + Q + + P + P + P P +S L +PA S
Sbjct: 420 VSNVFSGTTQNIISTNPTTVYPYRSPTYSVVIPSLQNPITHPVGETSPAIQLPTPAVQSP 479
Query: 485 ALASPAAPAATHSEQ------------AQPLSLTTKPETRAQLALHSAAFLSAKAAASSS 532
+ + P+ + + Q A P T P LHS A + K S
Sbjct: 480 SPVTLFQPSVSSAAQVAVQDPSLPVYPALPPQRFTGPSQTDTHQLHSEATHTVKQPTPVS 539
Query: 533 GQMGSQPPLLSRPLPLGSMPTALLASPPSFPATLHAHQALPVLQAQPL 580
+ ++ S T+ + P + + ++ P+ QA P+
Sbjct: 540 LESANRIS-SSASTAHARFATSTIQPPREYSSVSPCPRSAPIPQASPI 586
>gi|41406089 SRY-box 13 [Homo sapiens]
Length = 622
Score = 65.9 bits (159), Expect = 1e-10
Identities = 85/341 (24%), Positives = 136/341 (39%), Gaps = 61/341 (17%)
Query: 123 PFLMIPDLSSPYLSNGPLSPGGARTYLQMKWPLLDVPSSATVKDTRSPSPAHLSNKVPVV 182
P++MIP P P++P Q+ P+ +P K P S PVV
Sbjct: 225 PYVMIPAFP-PSHQPLPVTPDS-----QLALPIQPIPC----KPVEYPLQLLHSPPAPVV 274
Query: 183 QHPHHM---HPL---TPLITYSNDHFSPGSPPTHLSPEIDPKTGIPRPPHPSELSPYYPL 236
+ P M HPL + + + +P P T SP + + +PRPP +
Sbjct: 275 KRPGAMATHHPLQEPSQPLNLTAKPKAPELPNTSSSPSLKMSSCVPRPPSHGGPTRDLQS 334
Query: 237 SPGAVGQIPHPLGWL---------VPQQGQPMYSLPPGGFRHPYPALAMNASMSSLVSSR 287
SP ++ PLG+L + Q ++S G P + SL SS
Sbjct: 335 SPPSL-----PLGFLGEGDAVTKAIQDARQLLHS--HSGALDGSPNTPFRKDLISLDSS- 386
Query: 288 FSPHMVAPAHPGLPTSGIPHPAIVSPIVKQEPAPPSLSPAVSVKSPVTVKKEEEKKPHVK 347
PA L G HP E A S S P E H+K
Sbjct: 387 -------PAKERLE-DGCVHPL--------EEAMLSCDMDGSRHFP-----ESRNSSHIK 425
Query: 348 KPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRKWHNLSREEQAKYYELARKERQLHS 407
+P+NAFM++ K+ R K++ +++I++ILG +W +++ +E+ YYE + + H
Sbjct: 426 RPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARLSRQHL 485
Query: 408 QLYPTWSARDN-------YGKKKKRKREKQLSQTQSQQQVQ 441
+ YP + + GK+ + K L +T+ Q Q
Sbjct: 486 EKYPDYKYKPRPKRTCIVEGKRLRVGEYKALMRTRRQDARQ 526
Score = 38.1 bits (87), Expect = 0.023
Identities = 76/315 (24%), Positives = 112/315 (35%), Gaps = 72/315 (22%)
Query: 301 PTSGIPHPAIVSPIVKQEPAPPSLSPAVSVKSPVTVKKEEEKKPHVKKPLNAF---MLYM 357
P G P A Q PA + + SP E K+P V + + + +
Sbjct: 46 PQPGDPARASQDSADPQAPAQGNFRGSWDCSSPEGNGSPEPKRPGVSEAASGSQEKLDFN 105
Query: 358 KEMRAKVVAECTLKESAAINQILGRKWHNLSREEQAKYYELARKERQL----------HS 407
+ ++ V A L S + LGR +++ + LA KE QL
Sbjct: 106 RNLKEVVPAIEKLLSSDWKERFLGRNSME-AKDVKGTQESLAEKELQLLVMIHQLSTLRD 164
Query: 408 QLYPTWSARDNYGKKKKRKREKQLSQT-QSQQQVQEAEGALASKSKK------------- 453
QL S + N K+++Q+ Q Q+Q+ + + L + K
Sbjct: 165 QLLTAHSEQKNMAAMLFEKQQQQMELARQQQEQIAKQQQQLIQQQHKINLLQQQIQQVNM 224
Query: 454 ---------PCVQYLP--------------PEKPCDSPASSHGSMLDSPATPSAALASPA 490
P Q LP P KP + P +L SP P+ + P
Sbjct: 225 PYVMIPAFPPSHQPLPVTPDSQLALPIQPIPCKPVEYPLQ----LLHSP--PAPVVKRPG 278
Query: 491 APAATH--SEQAQPLSLTTKPETRAQLALHSAAFLSAKAAASSSGQMGSQPPLLSRPLPL 548
A A H E +QPL+LT KP+ A ++S S +M S P RP
Sbjct: 279 AMATHHPLQEPSQPLNLTAKPK----------APELPNTSSSPSLKMSSCVP---RPPSH 325
Query: 549 GSMPTALLASPPSFP 563
G L +SPPS P
Sbjct: 326 GGPTRDLQSSPPSLP 340
>gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Homo
sapiens]
Length = 841
Score = 65.5 bits (158), Expect = 1e-10
Identities = 32/106 (30%), Positives = 61/106 (57%), Gaps = 7/106 (6%)
Query: 343 KPHVKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRKWHNLSREEQAKYYELARKE 402
+PH+K+P+NAFM++ K+ R K++ ++ I++ILG +W ++S +E+ YYE +
Sbjct: 631 EPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARL 690
Query: 403 RQLHSQLYPTWSARDN-------YGKKKKRKREKQLSQTQSQQQVQ 441
++H + YP + + GKK + KQL +++ Q+ Q
Sbjct: 691 SKIHLEKYPNYKYKPRPKRTCIVDGKKLRIGEYKQLMRSRRQEMRQ 736
>gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Homo
sapiens]
Length = 801
Score = 65.5 bits (158), Expect = 1e-10
Identities = 32/106 (30%), Positives = 61/106 (57%), Gaps = 7/106 (6%)
Query: 343 KPHVKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRKWHNLSREEQAKYYELARKE 402
+PH+K+P+NAFM++ K+ R K++ ++ I++ILG +W ++S +E+ YYE +
Sbjct: 591 EPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARL 650
Query: 403 RQLHSQLYPTWSARDN-------YGKKKKRKREKQLSQTQSQQQVQ 441
++H + YP + + GKK + KQL +++ Q+ Q
Sbjct: 651 SKIHLEKYPNYKYKPRPKRTCIVDGKKLRIGEYKQLMRSRRQEMRQ 696
>gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo
sapiens]
Length = 804
Score = 65.5 bits (158), Expect = 1e-10
Identities = 32/106 (30%), Positives = 61/106 (57%), Gaps = 7/106 (6%)
Query: 343 KPHVKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRKWHNLSREEQAKYYELARKE 402
+PH+K+P+NAFM++ K+ R K++ ++ I++ILG +W ++S +E+ YYE +
Sbjct: 594 EPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARL 653
Query: 403 RQLHSQLYPTWSARDN-------YGKKKKRKREKQLSQTQSQQQVQ 441
++H + YP + + GKK + KQL +++ Q+ Q
Sbjct: 654 SKIHLEKYPNYKYKPRPKRTCIVDGKKLRIGEYKQLMRSRRQEMRQ 699
>gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo
sapiens]
Length = 808
Score = 65.5 bits (158), Expect = 1e-10
Identities = 32/106 (30%), Positives = 61/106 (57%), Gaps = 7/106 (6%)
Query: 343 KPHVKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRKWHNLSREEQAKYYELARKE 402
+PH+K+P+NAFM++ K+ R K++ ++ I++ILG +W ++S +E+ YYE +
Sbjct: 598 EPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARL 657
Query: 403 RQLHSQLYPTWSARDN-------YGKKKKRKREKQLSQTQSQQQVQ 441
++H + YP + + GKK + KQL +++ Q+ Q
Sbjct: 658 SKIHLEKYPNYKYKPRPKRTCIVDGKKLRIGEYKQLMRSRRQEMRQ 703
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 65.5 bits (158), Expect = 1e-10
Identities = 92/338 (27%), Positives = 118/338 (34%), Gaps = 40/338 (11%)
Query: 5 GGGGGGGGGGSGGGGGSSAGAAGGGDDL--GANDELIPFQDEGGEEQEPSSDSASAQRDL 62
G G GGGGGG GGGGG G GGG G + + G + S +A+ D
Sbjct: 64 GAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRS--TANRDNDS 121
Query: 63 DEVKSSLVNESENQSSS---------------SDSEAERRPQPVRDTFQKPRDYFAEVRR 107
+ L+ +S+ S P+P R+ PR +V
Sbjct: 122 GGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPR---PDVGS 178
Query: 108 PQDSAFFKGPPYPGYPFLMIPDLSSPYLSNGPLSPGGARTYLQMKWPLLDVPSSATVKDT 167
DS PP P P P SSP+ P PGG R P + T
Sbjct: 179 KPDSI---PPPVPSTP---RPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGG 232
Query: 168 RSPSPAHLSNKVPVVQHPHHMHPLTPLITYSNDHFSPGSPPTHLSPEIDPKTGIPRPPHP 227
S + LS+ P P PL P + + D P PP + + +P PP P
Sbjct: 233 GSIRQSPLSSSSPFSNRP----PLPPTPSRALDDKPPPPPPPVGNRPSIHREAVP-PPPP 287
Query: 228 SELSPYYPLS--PGAVGQIPHPLGWLVPQQGQPMYSLPPGGFRHPYPALAM-NASMSSLV 284
P P + P A Q P P P + P P P L N S+SS
Sbjct: 288 QNNKPPVPSTPRPSASSQAPPPPP--PPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSST 345
Query: 285 SSRFSPHMVAPAHPGLPTSGIPHPAIVSPIVKQEPAPP 322
SP P P P S P P + P + P PP
Sbjct: 346 PPLPSPGRSGPLPP--PPSERPPPPVRDPPGRSGPLPP 381
Score = 63.9 bits (154), Expect = 4e-10
Identities = 104/386 (26%), Positives = 136/386 (35%), Gaps = 79/386 (20%)
Query: 5 GGGGGGGGGGSGGGGGSSAGAAGGGDDLG-------------ANDELIPFQDEGGEEQE- 50
GGGGG GGGG GGGGGS G GG LG AN + D GG
Sbjct: 75 GGGGGFGGGGGGGGGGSFGG--GGPPGLGGLFQAGMPKLRSTANRD----NDSGGSRPPL 128
Query: 51 --PSSDSASAQRDLDEVKSSL--VNESENQSSSSDSEAERRPQPVRDTFQKPRDYFAEV- 105
P S SA+ V ++S + + R P P D KP V
Sbjct: 129 LPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVP 188
Query: 106 ---RRPQDSAFFKG-PPYPGYPFLMIPDLSSP--------YLSNGPL--SPGGARTYLQM 151
R Q S +G PP PG P P + P L G + SP + +
Sbjct: 189 STPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSN 248
Query: 152 KWPLLDVPSSATVKDTRSPSPAHLSNKVPVVQHPHHMHPLTPLITYSNDHFSPGSPPTHL 211
+ PL PS A + D P P + N+ + H + P +N PP
Sbjct: 249 RPPLPPTPSRA-LDDKPPPPPPPVGNRPSI-----HREAVPPPPPQNN------KPPVPS 296
Query: 212 SPEIDPKTGIPRPPHPSELSPYYPLSPGAVGQIPHPLGWLVPQQGQPMYS---------- 261
+P + P PP P PL P + G P +PQ+ + S
Sbjct: 297 TPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETP---RLPQRNLSLSSSTPPLPSPGR 353
Query: 262 ---LPPGGFRHPYPALAMNASMSS------LVSSRFSPHMVAPAHPGLPT-SGI--PHPA 309
LPP P P + S VS S PA P LP+ SG+ P
Sbjct: 354 SGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSG 413
Query: 310 IVSPIVKQEP---APPSLSPAVSVKS 332
P+ P APP P+ S+++
Sbjct: 414 PRPPLPPDRPSAGAPPPPPPSTSIRN 439
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 65.5 bits (158), Expect = 1e-10
Identities = 92/338 (27%), Positives = 118/338 (34%), Gaps = 40/338 (11%)
Query: 5 GGGGGGGGGGSGGGGGSSAGAAGGGDDL--GANDELIPFQDEGGEEQEPSSDSASAQRDL 62
G G GGGGGG GGGGG G GGG G + + G + S +A+ D
Sbjct: 64 GAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRS--TANRDNDS 121
Query: 63 DEVKSSLVNESENQSSS---------------SDSEAERRPQPVRDTFQKPRDYFAEVRR 107
+ L+ +S+ S P+P R+ PR +V
Sbjct: 122 GGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPR---PDVGS 178
Query: 108 PQDSAFFKGPPYPGYPFLMIPDLSSPYLSNGPLSPGGARTYLQMKWPLLDVPSSATVKDT 167
DS PP P P P SSP+ P PGG R P + T
Sbjct: 179 KPDSI---PPPVPSTP---RPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGG 232
Query: 168 RSPSPAHLSNKVPVVQHPHHMHPLTPLITYSNDHFSPGSPPTHLSPEIDPKTGIPRPPHP 227
S + LS+ P P PL P + + D P PP + + +P PP P
Sbjct: 233 GSIRQSPLSSSSPFSNRP----PLPPTPSRALDDKPPPPPPPVGNRPSIHREAVP-PPPP 287
Query: 228 SELSPYYPLS--PGAVGQIPHPLGWLVPQQGQPMYSLPPGGFRHPYPALAM-NASMSSLV 284
P P + P A Q P P P + P P P L N S+SS
Sbjct: 288 QNNKPPVPSTPRPSASSQAPPPPP--PPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSST 345
Query: 285 SSRFSPHMVAPAHPGLPTSGIPHPAIVSPIVKQEPAPP 322
SP P P P S P P + P + P PP
Sbjct: 346 PPLPSPGRSGPLPP--PPSERPPPPVRDPPGRSGPLPP 381
Score = 63.9 bits (154), Expect = 4e-10
Identities = 104/386 (26%), Positives = 136/386 (35%), Gaps = 79/386 (20%)
Query: 5 GGGGGGGGGGSGGGGGSSAGAAGGGDDLG-------------ANDELIPFQDEGGEEQE- 50
GGGGG GGGG GGGGGS G GG LG AN + D GG
Sbjct: 75 GGGGGFGGGGGGGGGGSFGG--GGPPGLGGLFQAGMPKLRSTANRD----NDSGGSRPPL 128
Query: 51 --PSSDSASAQRDLDEVKSSL--VNESENQSSSSDSEAERRPQPVRDTFQKPRDYFAEV- 105
P S SA+ V ++S + + R P P D KP V
Sbjct: 129 LPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVP 188
Query: 106 ---RRPQDSAFFKG-PPYPGYPFLMIPDLSSP--------YLSNGPL--SPGGARTYLQM 151
R Q S +G PP PG P P + P L G + SP + +
Sbjct: 189 STPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSN 248
Query: 152 KWPLLDVPSSATVKDTRSPSPAHLSNKVPVVQHPHHMHPLTPLITYSNDHFSPGSPPTHL 211
+ PL PS A + D P P + N+ + H + P +N PP
Sbjct: 249 RPPLPPTPSRA-LDDKPPPPPPPVGNRPSI-----HREAVPPPPPQNN------KPPVPS 296
Query: 212 SPEIDPKTGIPRPPHPSELSPYYPLSPGAVGQIPHPLGWLVPQQGQPMYS---------- 261
+P + P PP P PL P + G P +PQ+ + S
Sbjct: 297 TPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETP---RLPQRNLSLSSSTPPLPSPGR 353
Query: 262 ---LPPGGFRHPYPALAMNASMSS------LVSSRFSPHMVAPAHPGLPT-SGI--PHPA 309
LPP P P + S VS S PA P LP+ SG+ P
Sbjct: 354 SGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSG 413
Query: 310 IVSPIVKQEP---APPSLSPAVSVKS 332
P+ P APP P+ S+++
Sbjct: 414 PRPPLPPDRPSAGAPPPPPPSTSIRN 439
>gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens]
Length = 466
Score = 65.5 bits (158), Expect = 1e-10
Identities = 47/185 (25%), Positives = 84/185 (45%), Gaps = 11/185 (5%)
Query: 330 VKSPVTVKKEEEKKPHVKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRKWHNLSR 389
V PV V + KPHVK+P+NAFM++ + R K+ + +A +++ LG+ W L+
Sbjct: 88 VPMPVRVNGASKSKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNE 147
Query: 390 EEQAKYYELARKERQLHSQLYPTWSARDNYGKKKKRKREKQLSQTQSQQQVQEAE-GALA 448
++ + E A + R H + +P +Y + +R++ + +Q +++ EAE G A
Sbjct: 148 SDKRPFIEEAERLRMQHKKDHP------DYKYQPRRRKNGKAAQGEAECPGGEAEQGGTA 201
Query: 449 SKSKKPCVQYLPPEKPCDSPASSHGSMLDSPATPSAALASPAAPAATHSEQAQPLSLTTK 508
+ +L P + S G +P PS P P T + Q K
Sbjct: 202 AIQAHYKSAHLDHRHPGEGSPMSDG----NPEHPSGQSHGPPTPPTTPKTELQSGKADPK 257
Query: 509 PETRA 513
+ R+
Sbjct: 258 RDGRS 262
>gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo
sapiens]
Length = 501
Score = 62.4 bits (150), Expect = 1e-09
Identities = 33/116 (28%), Positives = 61/116 (52%)
Query: 309 AIVSPIVKQEPAPPSLSPAVSVKSPVTVKKEEEKKPHVKKPLNAFMLYMKEMRAKVVAEC 368
+++ P VK E L+ S +++ HVK+P+NAFM++ + R +
Sbjct: 300 SLLEPSVKIETKDVPLTVLPSDAGIPDTPFSKDRNGHVKRPMNAFMVWARIHRPALAKAN 359
Query: 369 TLKESAAINQILGRKWHNLSREEQAKYYELARKERQLHSQLYPTWSARDNYGKKKK 424
+A I+ LG +W+ LS E++ YY+ A+K ++ H + +P W + GK+K+
Sbjct: 360 PAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKEKHREEFPGWVYQPRPGKRKR 415
>gi|5902108 SRY-box 21 [Homo sapiens]
Length = 276
Score = 61.2 bits (147), Expect = 3e-09
Identities = 55/222 (24%), Positives = 95/222 (42%), Gaps = 28/222 (12%)
Query: 345 HVKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRKWHNLSREEQAKYYELARKERQ 404
HVK+P+NAFM++ + R K+ E ++ I++ LG +W L+ E+ + + A++ R
Sbjct: 7 HVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRA 66
Query: 405 LHSQLYPTWSARDNYGKKKKRKREKQL--------SQTQSQQQVQEAEGAL---ASKSKK 453
+H + +P + R K K++K ++ +A L A
Sbjct: 67 MHMKEHPDYKYRPRRKPKTLLKKDKFAFPVPYGLGGVADAEHPALKAGAGLHAGAGGGLV 126
Query: 454 PCVQYLPPEKPCDSPASSHGSMLDSPATPSAALASPAAPAA----------------THS 497
P PEK + A++ + + P + +AA A+ AA AA + S
Sbjct: 127 PESLLANPEKAA-AAAAAAAARVFFPQSAAAAAAAAAAAAAGSPYSLLDLGSKMAEISSS 185
Query: 498 EQAQPLSLTTKPETRAQLALHSAAFLSAKAAASSSGQMGSQP 539
P + + T A H AA +A AAA++ G S P
Sbjct: 186 SSGLPYASSLGYPTAGAGAFHGAAAAAAAAAAAAGGHTHSHP 227
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.128 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,676,738
Number of Sequences: 37866
Number of extensions: 1900334
Number of successful extensions: 32443
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 521
Number of HSP's successfully gapped in prelim test: 887
Number of HSP's that attempted gapping in prelim test: 16279
Number of HSP's gapped (non-prelim): 9735
length of query: 588
length of database: 18,247,518
effective HSP length: 108
effective length of query: 480
effective length of database: 14,157,990
effective search space: 6795835200
effective search space used: 6795835200
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.