Guide to the Human Genome
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Search of human proteins with 6912348

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|6912348 lysophosphatidic acid receptor 3 [Homo sapiens]
         (353 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|6912348 lysophosphatidic acid receptor 3 [Homo sapiens]            715   0.0  
gi|16950638 lysophosphatidic acid receptor 1 [Homo sapiens]           368   e-102
gi|16950636 lysophosphatidic acid receptor 1 [Homo sapiens]           368   e-102
gi|7305013 lysophosphatidic acid receptor 2 [Homo sapiens]            331   5e-91
gi|13027636 sphingosine-1-phosphate receptor 1 [Homo sapiens]         206   3e-53
gi|38788193 sphingosine-1-phosphate receptor 3 [Homo sapiens]         205   6e-53
gi|134244587 endothelial differentiation, sphingolipid G-protein...   186   2e-47
gi|13540517 endothelial differentiation, sphingolipid G-protein-...   174   1e-43
gi|4503459 sphingosine-1-phosphate receptor 4 precursor [Homo sa...   161   9e-40
gi|4885325 G protein-coupled receptor 3 [Homo sapiens]                131   1e-30
gi|237681179 cannabinoid receptor 1 isoform a [Homo sapiens]          129   3e-30
gi|237681175 cannabinoid receptor 1 isoform a [Homo sapiens]          129   3e-30
gi|237681173 cannabinoid receptor 1 isoform a [Homo sapiens]          129   3e-30
gi|237681067 cannabinoid receptor 1 isoform a [Homo sapiens]          129   3e-30
gi|38683844 cannabinoid receptor 1 isoform a [Homo sapiens]           129   3e-30
gi|237681065 cannabinoid receptor 1 isoform b [Homo sapiens]          129   3e-30
gi|4885295 G protein-coupled receptor 12 [Homo sapiens]               124   1e-28
gi|4885341 G protein-coupled receptor 6 [Homo sapiens]                119   5e-27
gi|5174535 melanocortin 5 receptor [Homo sapiens]                     116   3e-26
gi|119508433 melanocortin 4 receptor [Homo sapiens]                   114   2e-25
gi|170671732 melanocortin 3 receptor [Homo sapiens]                   103   2e-22
gi|4502929 cannabinoid receptor 2 (macrophage) [Homo sapiens]         100   2e-21
gi|4504533 5-hydroxytryptamine (serotonin) receptor 1B [Homo sap...    96   5e-20
gi|4501951 adenosine A2b receptor [Homo sapiens]                       89   6e-18
gi|5921992 adenosine A2a receptor [Homo sapiens]                       87   2e-17
gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]                 83   4e-16
gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens]          82   6e-16
gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]          82   7e-16
gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]          82   7e-16
gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens]          82   7e-16

>gi|6912348 lysophosphatidic acid receptor 3 [Homo sapiens]
          Length = 353

 Score =  715 bits (1845), Expect = 0.0
 Identities = 353/353 (100%), Positives = 353/353 (100%)

Query: 1   MNECHYDKHMDFFYNRSNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRK 60
           MNECHYDKHMDFFYNRSNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRK
Sbjct: 1   MNECHYDKHMDFFYNRSNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRK 60

Query: 61  FHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNL 120
           FHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNL
Sbjct: 61  FHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNL 120

Query: 121 LVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLA 180
           LVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLA
Sbjct: 121 LVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLA 180

Query: 181 PIYSRSYLVFWTVSNLMAFLIMVVVYLRIYVYVKRKTNVLSPHTSGSISRRRTPMKLMKT 240
           PIYSRSYLVFWTVSNLMAFLIMVVVYLRIYVYVKRKTNVLSPHTSGSISRRRTPMKLMKT
Sbjct: 181 PIYSRSYLVFWTVSNLMAFLIMVVVYLRIYVYVKRKTNVLSPHTSGSISRRRTPMKLMKT 240

Query: 241 VMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDM 300
           VMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDM
Sbjct: 241 VMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDM 300

Query: 301 YGTMKKMICCFSQENPERRPSRIPSTVLSRSDTGSQYIEDSISQGAVCNKSTS 353
           YGTMKKMICCFSQENPERRPSRIPSTVLSRSDTGSQYIEDSISQGAVCNKSTS
Sbjct: 301 YGTMKKMICCFSQENPERRPSRIPSTVLSRSDTGSQYIEDSISQGAVCNKSTS 353


>gi|16950638 lysophosphatidic acid receptor 1 [Homo sapiens]
          Length = 364

 Score =  368 bits (944), Expect = e-102
 Identities = 173/338 (51%), Positives = 250/338 (73%), Gaps = 11/338 (3%)

Query: 1   MNE--CHYDKHMDFFYNRSNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKN 58
           MNE  C Y++ + FFYNRS      +W  T   +V+ +G   C+FI  +N LV+ A+  N
Sbjct: 19  MNEPQCFYNESIAFFYNRSGKHLATEWN-TVSKLVMGLGITVCIFIMLANLLVMVAIYVN 77

Query: 59  RKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDSSLTASLT 118
           R+FHFP YYL+ANLAAADFFAG+AY +LMFNTGP ++ LTV+ W LRQGL+D+SLTAS+ 
Sbjct: 78  RRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVA 137

Query: 119 NLLVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSS 178
           NLL IA+ERH+++ RM++H+ ++ +RV ++I+++W +AI MGA+P++GWNC+C+I  CS+
Sbjct: 138 NLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSN 197

Query: 179 LAPIYSRSYLVFWTVSNLMAFLIMVVVYLRIYVYVKRKTNVLSPHTSGSISRRRTPMKLM 238
           +AP+YS SYLVFW + NL+ F++MVV+Y  I+ YV+++T  +S H+SG    R T M L+
Sbjct: 198 MAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMSRHSSGPRRNRDTMMSLL 257

Query: 239 KTVMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDE 298
           KTV+ VLGAF++CWTPGLV+LLLD + C QC V   +++FLLLA  NS +NPIIYSY+D+
Sbjct: 258 KTVVIVLGAFIICWTPGLVLLLLD-VCCPQCDVLAYEKFFLLLAEFNSAMNPIIYSYRDK 316

Query: 299 DMYGTMKKMICCFSQENP-------ERRPSRIPSTVLS 329
           +M  T ++++CC   ENP       +R  S +  T+L+
Sbjct: 317 EMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILA 354


>gi|16950636 lysophosphatidic acid receptor 1 [Homo sapiens]
          Length = 364

 Score =  368 bits (944), Expect = e-102
 Identities = 173/338 (51%), Positives = 250/338 (73%), Gaps = 11/338 (3%)

Query: 1   MNE--CHYDKHMDFFYNRSNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKN 58
           MNE  C Y++ + FFYNRS      +W  T   +V+ +G   C+FI  +N LV+ A+  N
Sbjct: 19  MNEPQCFYNESIAFFYNRSGKHLATEWN-TVSKLVMGLGITVCIFIMLANLLVMVAIYVN 77

Query: 59  RKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDSSLTASLT 118
           R+FHFP YYL+ANLAAADFFAG+AY +LMFNTGP ++ LTV+ W LRQGL+D+SLTAS+ 
Sbjct: 78  RRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVA 137

Query: 119 NLLVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSS 178
           NLL IA+ERH+++ RM++H+ ++ +RV ++I+++W +AI MGA+P++GWNC+C+I  CS+
Sbjct: 138 NLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSN 197

Query: 179 LAPIYSRSYLVFWTVSNLMAFLIMVVVYLRIYVYVKRKTNVLSPHTSGSISRRRTPMKLM 238
           +AP+YS SYLVFW + NL+ F++MVV+Y  I+ YV+++T  +S H+SG    R T M L+
Sbjct: 198 MAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMSRHSSGPRRNRDTMMSLL 257

Query: 239 KTVMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDE 298
           KTV+ VLGAF++CWTPGLV+LLLD + C QC V   +++FLLLA  NS +NPIIYSY+D+
Sbjct: 258 KTVVIVLGAFIICWTPGLVLLLLD-VCCPQCDVLAYEKFFLLLAEFNSAMNPIIYSYRDK 316

Query: 299 DMYGTMKKMICCFSQENP-------ERRPSRIPSTVLS 329
           +M  T ++++CC   ENP       +R  S +  T+L+
Sbjct: 317 EMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILA 354


>gi|7305013 lysophosphatidic acid receptor 2 [Homo sapiens]
          Length = 351

 Score =  331 bits (849), Expect = 5e-91
 Identities = 157/310 (50%), Positives = 217/310 (70%), Gaps = 1/310 (0%)

Query: 1   MNECHYDKHMDFFYNRSNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRK 60
           M +C+Y++ + FFYN S  +    W   K V+V+ +G    + +  +N LVIAA+  NR+
Sbjct: 4   MGQCYYNETIGFFYNNSGKELSSHWR-PKDVVVVALGLTVSVLVLLTNLLVIAAIASNRR 62

Query: 61  FHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNL 120
           FH P YYLL NLAAAD FAG+AY+FLMF+TGP +  L++  WFLRQGLLD+SLTAS+  L
Sbjct: 63  FHQPIYYLLGNLAAADLFAGVAYLFLMFHTGPRTARLSLEGWFLRQGLLDTSLTASVATL 122

Query: 121 LVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLA 180
           L IAVERH S+M +++HS L + RV +LI+ VW  A+ +G +P   W+CLC +  CS +A
Sbjct: 123 LAIAVERHRSVMAVQLHSRLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMA 182

Query: 181 PIYSRSYLVFWTVSNLMAFLIMVVVYLRIYVYVKRKTNVLSPHTSGSISRRRTPMKLMKT 240
           P+ SRSYL  W +S+L+ FL+MV VY RI+ YV+R+   ++ H S     R T + L+KT
Sbjct: 183 PLLSRSYLAVWALSSLLVFLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRETTLSLVKT 242

Query: 241 VMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDM 300
           V+ +LGAFVVCWTPG VVLLLDGL C  C V  V+++FLLLA  NS+VN  +YS +D +M
Sbjct: 243 VVIILGAFVVCWTPGQVVLLLDGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDAEM 302

Query: 301 YGTMKKMICC 310
             T ++++CC
Sbjct: 303 RRTFRRLLCC 312


>gi|13027636 sphingosine-1-phosphate receptor 1 [Homo sapiens]
          Length = 382

 Score =  206 bits (523), Expect = 3e-53
 Identities = 103/293 (35%), Positives = 176/293 (60%), Gaps = 5/293 (1%)

Query: 21  TVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFHFPFYYLLANLAAADFFAG 80
           + D     KL  V+ +    C FI   N  V+  + K +KFH P YY + NLA +D  AG
Sbjct: 38  SADKENSIKLTSVVFI--LICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAG 95

Query: 81  IAYVFLMFNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNLLVIAVERHMSIMRMRVHSNL 140
           +AY   +  +G  +  LT  +WFLR+G +  +L+AS+ +LL IA+ER++++++M++H+  
Sbjct: 96  VAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGS 155

Query: 141 TKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAFL 200
              R+ LLI   W I++ +G +P +GWNC+  +S+CS++ P+Y + Y++F T    +  L
Sbjct: 156 NNFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLL 215

Query: 201 IMVVVYLRIYVYVKRKTNVLSPHTSGSISRRRT--PMKLMKTVMTVLGAFVVCWTPGLVV 258
            +V++Y RIY  V+ ++  L+   + S + R +   + L+KTV+ VL  F+ CW P  ++
Sbjct: 216 SIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFIL 275

Query: 259 LLLD-GLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKMICC 310
           LLLD G   + C +     +FL+LA+LNS  NPIIY+  +++M     +++ C
Sbjct: 276 LLLDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSC 328


>gi|38788193 sphingosine-1-phosphate receptor 3 [Homo sapiens]
          Length = 378

 Score =  205 bits (521), Expect = 6e-53
 Identities = 115/313 (36%), Positives = 183/313 (58%), Gaps = 13/313 (4%)

Query: 27  GTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFHFPFYYLLANLAAADFFAGIAYVFL 86
           G+ L  VL +    C FI   N +V+ A+ KN KFH   Y+ + NLA  D  AGIAY   
Sbjct: 38  GSTLTTVLFL--VICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVN 95

Query: 87  MFNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNLLVIAVERHMSIMRMRVHSNLTKKRVT 146
           +  +G  + +L+   WFLR+G +  +L AS  +LL IA+ERH+++++MR +    + RV 
Sbjct: 96  ILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVF 155

Query: 147 LLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAFLI-MVVV 205
           LLI + W IA  +GA+P LGWNCL N+  CS++ P+YS+ Y+ F  +S   A L+ +V++
Sbjct: 156 LLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAF-CISIFTAILVTIVIL 214

Query: 206 YLRIYVYVKRKTNVLSPHTSGSISRRRTPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLN 265
           Y RIY  VK  +  ++ H +   S     M L++TV+ V+  F+ CW+P  ++ L+D + 
Sbjct: 215 YARIYFLVKSSSRKVANHNNSERS-----MALLRTVVIVVSVFIACWSPLFILFLID-VA 268

Query: 266 CR--QCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKMIC-CFSQENPERRPSR 322
           CR   C +    +WF++LA+LNS +NP+IY+   ++M     +++C C  +    R    
Sbjct: 269 CRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLVRGRGARASPI 328

Query: 323 IPSTVLSRSDTGS 335
            P+   SRS + S
Sbjct: 329 QPALDPSRSKSSS 341


>gi|134244587 endothelial differentiation, sphingolipid
           G-protein-coupled receptor, 5 [Homo sapiens]
          Length = 353

 Score =  186 bits (473), Expect = 2e-47
 Identities = 99/294 (33%), Positives = 168/294 (57%), Gaps = 18/294 (6%)

Query: 20  DTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFHFPFYYLLANLAAADFFA 79
           +T      +  +++LC        I   N LV+ AV +N KFH   Y  L NLAA+D  A
Sbjct: 29  ETTSRQVASAFIVILCCA------IVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLA 82

Query: 80  GIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNLLVIAVERHMSIMRMRVHSN 139
           G+A+V     +G V+  LT  +WF R+G    +L+AS+ +LL IA+ERH++I +++++ +
Sbjct: 83  GVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGS 142

Query: 140 LTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAF 199
               R+ LLI   W I++ +G +P LGWNCL ++ ACS++ P+Y++ Y++       +  
Sbjct: 143 DKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIIL 202

Query: 200 LIMVVVYLRIYVYVKRK-TNVLSPHTSGSISRRRTPMKLMKTVMTVLGAFVVCWTPGLVV 258
           L +V +Y+RIY  V+    ++ +P T          + L+KTV  VLG F+VCW P   +
Sbjct: 203 LAIVALYVRIYCVVRSSHADMAAPQT----------LALLKTVTIVLGVFIVCWLPAFSI 252

Query: 259 LLLD-GLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKMICCF 311
           LLLD       C + +   +F  ++ LNS++NP+IY+++  D+   + + + C+
Sbjct: 253 LLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCW 306


>gi|13540517 endothelial differentiation, sphingolipid
           G-protein-coupled receptor, 8 [Homo sapiens]
          Length = 398

 Score =  174 bits (440), Expect = 1e-43
 Identities = 98/291 (33%), Positives = 164/291 (56%), Gaps = 9/291 (3%)

Query: 27  GTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFHFPFYYLLANLAAADFFAGIAYVFL 86
           G +   V+C+    C FI   N  V+  + ++ +FH P + LL +L  +D  AG AY   
Sbjct: 35  GLRADAVVCLAV--CAFIVLENLAVLLVLGRHPRFHAPMFLLLGSLTLSDLLAGAAYAAN 92

Query: 87  MFNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNLLVIAVERHMSIMRMRVHSNLTKKRVT 146
           +  +GP++  L+   WF R+G +  +LTAS+ +LL IA+ER +++ R       ++ R  
Sbjct: 93  ILLSGPLTLKLSPALWFAREGGVFVALTASVLSLLAIALERSLTMARRGPAPVSSRGRTL 152

Query: 147 LLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAFLIMVVVY 206
            +    W +++ +G +P LGWNCL  + ACS++ P+Y+++Y++F  ++ +     +  +Y
Sbjct: 153 AMAAAAWGVSLLLGLLPALGWNCLGRLDACSTVLPLYAKAYVLFCVLAFVGILAAICALY 212

Query: 207 LRIYVYVKRKTNVL--SPHTSGSIS--RRRTP--MKLMKTVMTVLGAFVVCWTPGLVVLL 260
            RIY  V+     L   P T+G+ S   RR P  + L++T+  VL AFV CW P  ++LL
Sbjct: 213 ARIYCQVRANARRLPARPGTAGTTSTRARRKPRSLALLRTLSVVLLAFVACWGPLFLLLL 272

Query: 261 LD-GLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKMICC 310
           LD     R C V      FL LA+ NS++NPIIY+  + D+   + +++CC
Sbjct: 273 LDVACPARTCPVLLQADPFLGLAMANSLLNPIIYTLTNRDLRHALLRLVCC 323


>gi|4503459 sphingosine-1-phosphate receptor 4 precursor [Homo
           sapiens]
          Length = 384

 Score =  161 bits (407), Expect = 9e-40
 Identities = 97/273 (35%), Positives = 148/273 (54%), Gaps = 9/273 (3%)

Query: 41  CLFIFFSNSLVIAAVIKNRKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVN 100
           CL +   N LV+AA+  + +     YY L N+  +D   G AY+  +  +G  +  L   
Sbjct: 58  CLVVL-ENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPA 116

Query: 101 RWFLRQGLLDSSLTASLTNLLVIAVERHMSIMRMRVHSNLTK-KRVTLLILLVWAIAIFM 159
           +WFLR+GLL ++L AS  +LL  A ER  +++R    S  TK  RV   I L W +A  +
Sbjct: 117 QWFLREGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALL 176

Query: 160 GAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAFLIMVVVYLRIYVYVKRKTNV 219
           G +P LGWNCLC    CSSL P+YS+ Y++F     L+ F  ++   + +Y  + R    
Sbjct: 177 GMLPLLGWNCLCAFDRCSSLLPLYSKRYILFC----LVIFAGVLATIMGLYGAIFRLVQA 232

Query: 220 LSPHTSGSISRRRTPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVK--RW 277
            S   +   + RR   +L+KTV+ +L AF+VCW P   +LL D         ++++   W
Sbjct: 233 -SGQKAPRPAARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDW 291

Query: 278 FLLLALLNSVVNPIIYSYKDEDMYGTMKKMICC 310
            L LA+LNS VNPIIYS++  ++   +   +CC
Sbjct: 292 ILALAVLNSAVNPIIYSFRSREVCRAVLSFLCC 324


>gi|4885325 G protein-coupled receptor 3 [Homo sapiens]
          Length = 330

 Score =  131 bits (329), Expect = 1e-30
 Identities = 98/307 (31%), Positives = 154/307 (50%), Gaps = 32/307 (10%)

Query: 32  IVLCV-GTFFCLFIFFSNSLVIAAVIKNRKFHFPFYYLLANLAAADFFAGIAYVF---LM 87
           +VLC+ GT     +   N+LV+A ++    F  P + L+ +LA AD  AG+  V     +
Sbjct: 45  VVLCISGTL----VSCENALVVAIIVGTPAFRAPMFLLVGSLAVADLLAGLGLVLHFAAV 100

Query: 88  FNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNLLVIAVERHMSIMR-MRVHSNLTKKRVT 146
           F  G    +L +       G+L  + TAS+ +LL I V+R++S+   +  +S  T  R  
Sbjct: 101 FCIGSAEMSLVL------VGVLAMAFTASIGSLLAITVDRYLSLYNALTYYSETTVTRTY 154

Query: 147 LLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAFLIMVVVY 206
           +++ LVW  A+ +G +P L WNCL  ++ C  + P+ S+++LV   ++  M F IM+ +Y
Sbjct: 155 VMLALVWGGALGLGLLPVLAWNCLDGLTTCGVVYPL-SKNHLVVLAIAFFMVFGIMLQLY 213

Query: 207 LRIYVYVKRKTN--VLSPHTSGSISRRRTPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGL 264
            +I   V R      L  H   + S      K + T+  VLGAF  CW P  V  LL   
Sbjct: 214 AQICRIVCRHAQQIALQRHLLPA-SHYVATRKGIATLAVVLGAFAACWLPFTVYCLL--- 269

Query: 265 NCRQCGVQHVKRWFLLLALL----NSVVNPIIYSYKDEDMYGTMKKMICCFSQENPERRP 320
                G  H    +  L LL    NS++NPIIY+++++D+   +  + CC S      R 
Sbjct: 270 -----GDAHSPPLYTYLTLLPATYNSMINPIIYAFRNQDVQKVLWAVCCCCSSSKIPFR- 323

Query: 321 SRIPSTV 327
           SR PS V
Sbjct: 324 SRSPSDV 330


>gi|237681179 cannabinoid receptor 1 isoform a [Homo sapiens]
          Length = 472

 Score =  129 bits (325), Expect = 3e-30
 Identities = 80/297 (26%), Positives = 149/297 (50%), Gaps = 26/297 (8%)

Query: 31  VIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFHF-PFYYLLANLAAADFFAGIAYVFLMFN 89
           V+ L +GTF  L     N LV+  ++ +R     P Y+ + +LA AD    + +V+   +
Sbjct: 121 VLSLTLGTFTVL----ENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFID 176

Query: 90  TGPVSKTLTVNRWFLRQGLLDSSLTASLTNLLVIAVERHMSIMRMRVHSNL-TKKRVTLL 148
                +  + N +  + G + +S TAS+ +L + A++R++SI R   +  + T+ +  + 
Sbjct: 177 FHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVA 236

Query: 149 ILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAFLIMVVVYLR 208
             L+W IAI +  +P LGWNC    S CS + P    +YL+FW    + + L++ +VY  
Sbjct: 237 FCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWI--GVTSVLLLFIVYAY 294

Query: 209 IYVYVK-------------RKTNVLSPHTSGSI-----SRRRTPMKLMKTVMTVLGAFVV 250
           +Y+  K             +K+ ++     G +      + R  ++L KT++ +L   ++
Sbjct: 295 MYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLII 354

Query: 251 CWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKM 307
           CW P L +++ D        ++ V  +  +L LLNS VNPIIY+ + +D+    + M
Sbjct: 355 CWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSM 411


>gi|237681175 cannabinoid receptor 1 isoform a [Homo sapiens]
          Length = 472

 Score =  129 bits (325), Expect = 3e-30
 Identities = 80/297 (26%), Positives = 149/297 (50%), Gaps = 26/297 (8%)

Query: 31  VIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFHF-PFYYLLANLAAADFFAGIAYVFLMFN 89
           V+ L +GTF  L     N LV+  ++ +R     P Y+ + +LA AD    + +V+   +
Sbjct: 121 VLSLTLGTFTVL----ENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFID 176

Query: 90  TGPVSKTLTVNRWFLRQGLLDSSLTASLTNLLVIAVERHMSIMRMRVHSNL-TKKRVTLL 148
                +  + N +  + G + +S TAS+ +L + A++R++SI R   +  + T+ +  + 
Sbjct: 177 FHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVA 236

Query: 149 ILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAFLIMVVVYLR 208
             L+W IAI +  +P LGWNC    S CS + P    +YL+FW    + + L++ +VY  
Sbjct: 237 FCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWI--GVTSVLLLFIVYAY 294

Query: 209 IYVYVK-------------RKTNVLSPHTSGSI-----SRRRTPMKLMKTVMTVLGAFVV 250
           +Y+  K             +K+ ++     G +      + R  ++L KT++ +L   ++
Sbjct: 295 MYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLII 354

Query: 251 CWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKM 307
           CW P L +++ D        ++ V  +  +L LLNS VNPIIY+ + +D+    + M
Sbjct: 355 CWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSM 411


>gi|237681173 cannabinoid receptor 1 isoform a [Homo sapiens]
          Length = 472

 Score =  129 bits (325), Expect = 3e-30
 Identities = 80/297 (26%), Positives = 149/297 (50%), Gaps = 26/297 (8%)

Query: 31  VIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFHF-PFYYLLANLAAADFFAGIAYVFLMFN 89
           V+ L +GTF  L     N LV+  ++ +R     P Y+ + +LA AD    + +V+   +
Sbjct: 121 VLSLTLGTFTVL----ENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFID 176

Query: 90  TGPVSKTLTVNRWFLRQGLLDSSLTASLTNLLVIAVERHMSIMRMRVHSNL-TKKRVTLL 148
                +  + N +  + G + +S TAS+ +L + A++R++SI R   +  + T+ +  + 
Sbjct: 177 FHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVA 236

Query: 149 ILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAFLIMVVVYLR 208
             L+W IAI +  +P LGWNC    S CS + P    +YL+FW    + + L++ +VY  
Sbjct: 237 FCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWI--GVTSVLLLFIVYAY 294

Query: 209 IYVYVK-------------RKTNVLSPHTSGSI-----SRRRTPMKLMKTVMTVLGAFVV 250
           +Y+  K             +K+ ++     G +      + R  ++L KT++ +L   ++
Sbjct: 295 MYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLII 354

Query: 251 CWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKM 307
           CW P L +++ D        ++ V  +  +L LLNS VNPIIY+ + +D+    + M
Sbjct: 355 CWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSM 411


>gi|237681067 cannabinoid receptor 1 isoform a [Homo sapiens]
          Length = 472

 Score =  129 bits (325), Expect = 3e-30
 Identities = 80/297 (26%), Positives = 149/297 (50%), Gaps = 26/297 (8%)

Query: 31  VIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFHF-PFYYLLANLAAADFFAGIAYVFLMFN 89
           V+ L +GTF  L     N LV+  ++ +R     P Y+ + +LA AD    + +V+   +
Sbjct: 121 VLSLTLGTFTVL----ENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFID 176

Query: 90  TGPVSKTLTVNRWFLRQGLLDSSLTASLTNLLVIAVERHMSIMRMRVHSNL-TKKRVTLL 148
                +  + N +  + G + +S TAS+ +L + A++R++SI R   +  + T+ +  + 
Sbjct: 177 FHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVA 236

Query: 149 ILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAFLIMVVVYLR 208
             L+W IAI +  +P LGWNC    S CS + P    +YL+FW    + + L++ +VY  
Sbjct: 237 FCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWI--GVTSVLLLFIVYAY 294

Query: 209 IYVYVK-------------RKTNVLSPHTSGSI-----SRRRTPMKLMKTVMTVLGAFVV 250
           +Y+  K             +K+ ++     G +      + R  ++L KT++ +L   ++
Sbjct: 295 MYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLII 354

Query: 251 CWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKM 307
           CW P L +++ D        ++ V  +  +L LLNS VNPIIY+ + +D+    + M
Sbjct: 355 CWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSM 411


>gi|38683844 cannabinoid receptor 1 isoform a [Homo sapiens]
          Length = 472

 Score =  129 bits (325), Expect = 3e-30
 Identities = 80/297 (26%), Positives = 149/297 (50%), Gaps = 26/297 (8%)

Query: 31  VIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFHF-PFYYLLANLAAADFFAGIAYVFLMFN 89
           V+ L +GTF  L     N LV+  ++ +R     P Y+ + +LA AD    + +V+   +
Sbjct: 121 VLSLTLGTFTVL----ENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFID 176

Query: 90  TGPVSKTLTVNRWFLRQGLLDSSLTASLTNLLVIAVERHMSIMRMRVHSNL-TKKRVTLL 148
                +  + N +  + G + +S TAS+ +L + A++R++SI R   +  + T+ +  + 
Sbjct: 177 FHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVA 236

Query: 149 ILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAFLIMVVVYLR 208
             L+W IAI +  +P LGWNC    S CS + P    +YL+FW    + + L++ +VY  
Sbjct: 237 FCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWI--GVTSVLLLFIVYAY 294

Query: 209 IYVYVK-------------RKTNVLSPHTSGSI-----SRRRTPMKLMKTVMTVLGAFVV 250
           +Y+  K             +K+ ++     G +      + R  ++L KT++ +L   ++
Sbjct: 295 MYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLII 354

Query: 251 CWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKM 307
           CW P L +++ D        ++ V  +  +L LLNS VNPIIY+ + +D+    + M
Sbjct: 355 CWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSM 411


>gi|237681065 cannabinoid receptor 1 isoform b [Homo sapiens]
          Length = 439

 Score =  129 bits (325), Expect = 3e-30
 Identities = 80/297 (26%), Positives = 149/297 (50%), Gaps = 26/297 (8%)

Query: 31  VIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFHF-PFYYLLANLAAADFFAGIAYVFLMFN 89
           V+ L +GTF  L     N LV+  ++ +R     P Y+ + +LA AD    + +V+   +
Sbjct: 88  VLSLTLGTFTVL----ENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFID 143

Query: 90  TGPVSKTLTVNRWFLRQGLLDSSLTASLTNLLVIAVERHMSIMRMRVHSNL-TKKRVTLL 148
                +  + N +  + G + +S TAS+ +L + A++R++SI R   +  + T+ +  + 
Sbjct: 144 FHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVA 203

Query: 149 ILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAFLIMVVVYLR 208
             L+W IAI +  +P LGWNC    S CS + P    +YL+FW    + + L++ +VY  
Sbjct: 204 FCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWI--GVTSVLLLFIVYAY 261

Query: 209 IYVYVK-------------RKTNVLSPHTSGSI-----SRRRTPMKLMKTVMTVLGAFVV 250
           +Y+  K             +K+ ++     G +      + R  ++L KT++ +L   ++
Sbjct: 262 MYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLII 321

Query: 251 CWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKM 307
           CW P L +++ D        ++ V  +  +L LLNS VNPIIY+ + +D+    + M
Sbjct: 322 CWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSM 378


>gi|4885295 G protein-coupled receptor 12 [Homo sapiens]
          Length = 334

 Score =  124 bits (312), Expect = 1e-28
 Identities = 87/303 (28%), Positives = 154/303 (50%), Gaps = 24/303 (7%)

Query: 32  IVLCV-GTFFCLFIFFSNSLVIAAVIKNRKFHFPFYYLLANLAAADFFAGIA----YVFL 86
           IVLC  GT     I   N++V+  +  N     P + L+ +LA AD  AGI     +VF 
Sbjct: 49  IVLCTSGTL----ISCENAIVVLIIFHNPSLRAPMFLLIGSLALADLLAGIGLITNFVFA 104

Query: 87  MFNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNLLVIAVERHMSIM-RMRVHSNLTKKRV 145
                  +K +T+       GL+ +S +AS+ +LL I V+R++S+   +  HS  T    
Sbjct: 105 YLLQSEATKLVTI-------GLIVASFSASVCSLLAITVDRYLSLYYALTYHSERTVTFT 157

Query: 146 TLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAFLIMVVV 205
            ++++++W  +I +G +P +GWNCL + S CS + P+ +++     +VS L  F +M+ +
Sbjct: 158 YVMLVMLWGTSICLGLLPVMGWNCLRDESTCSVVRPL-TKNNAAILSVSFLFMFALMLQL 216

Query: 206 YLRIYVYVKRKTNVLS-PHTSGSISRRRTPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGL 264
           Y++I   V R  + ++  H   + S   T  K + T+  +LG F  CW P  +  L+   
Sbjct: 217 YIQICKIVMRHAHQIALQHHFLATSHYVTTRKGVSTLAIILGTFAACWMPFTLYSLIADY 276

Query: 265 NCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKMICCFSQENPERRPSRIP 324
                         LL A  NS++NP+IY+++++++   +  +ICC    +   + +R P
Sbjct: 277 TYPSIYTYAT----LLPATYNSIINPVIYAFRNQEIQKAL-CLICCGCIPSSLAQRARSP 331

Query: 325 STV 327
           S V
Sbjct: 332 SDV 334


>gi|4885341 G protein-coupled receptor 6 [Homo sapiens]
          Length = 362

 Score =  119 bits (297), Expect = 5e-27
 Identities = 92/308 (29%), Positives = 156/308 (50%), Gaps = 34/308 (11%)

Query: 32  IVLCV-GTFFCLFIFFSNSLVIAAVIKNRKFHFPFYYLLANLAAADFFAGIAYVF-LMFN 89
           ++LCV GT     I   N+LV+A +        P + L+ +LA AD  AG   +   +F 
Sbjct: 77  VLLCVSGTV----IAGENALVVALIASTPALRTPMFVLVGSLATADLLAGCGLILHFVFQ 132

Query: 90  TGPVSKTLTVNRWFLRQGLLDSSLTASLTNLLVIAVERHMSIMR-MRVHSNLTKKRVTLL 148
               S+T+++    L  G L +S  AS+++LL I V+R++S+   +  +S  T   V LL
Sbjct: 133 YLVPSETVSL----LTVGFLVASFAASVSSLLAITVDRYLSLYNALTYYSRRTLLGVHLL 188

Query: 149 ILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAFLIMVVVYLR 208
           +   W +++ +G +P LGWNCL   +ACS + P+ +RS++   + +  M F IM+ +Y+R
Sbjct: 189 LAATWTVSLGLGLLPVLGWNCLAERAACSVVRPL-ARSHVALLSAAFFMVFGIMLHLYVR 247

Query: 209 IYVYVKRKTNVLS--------PHTSGSISRRRTPMKLMKTVMTVLGAFVVCWTPGLVVLL 260
           I   V R  + ++        PH + +        K + T+  VLG F   W P  +  +
Sbjct: 248 ICQVVWRHAHQIALQQHCLAPPHLAAT-------RKGVGTLAVVLGTFGASWLPFAIYCV 300

Query: 261 LDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKMIC-CFSQENPERR 319
           +                 LL A  NS++NPIIY+++++++   +  ++C CF  + P R 
Sbjct: 301 VGSHEDPAVYTYAT----LLPATYNSMINPIIYAFRNQEIQRALWLLLCGCFQSKVPFR- 355

Query: 320 PSRIPSTV 327
            SR PS V
Sbjct: 356 -SRSPSEV 362


>gi|5174535 melanocortin 5 receptor [Homo sapiens]
          Length = 325

 Score =  116 bits (291), Expect = 3e-26
 Identities = 90/316 (28%), Positives = 157/316 (49%), Gaps = 48/316 (15%)

Query: 15  NRSNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFHFPFYYLLANLAA 74
           N  N  +  +  G  + + L +G    L     N LVI A++KN+  H P Y+ + +LA 
Sbjct: 25  NVKNKSSPCEDMGIAVEVFLTLGVISLL----ENILVIGAIVKNKNLHSPMYFFVCSLAV 80

Query: 75  ADFFAGIAY------VFLMFNTGPVSKTLTVNRWFLRQ--GLLDS----SLTASLTNLLV 122
           AD    ++       ++L+ N     K L +   F+R    + DS    S+ AS+ +LL 
Sbjct: 81  ADMLVSMSSAWETITIYLLNN-----KHLVIADAFVRHIDNVFDSMICISVVASMCSLLA 135

Query: 123 IAVERHMSIM-RMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAP 181
           IAV+R+++I   +R H  +T +R   +I  +WA                   + C  +  
Sbjct: 136 IAVDRYVTIFYALRYHHIMTARRSGAIIAGIWAFC-----------------TGCGIVFI 178

Query: 182 IYSRS-YLVFWTVSNLMAFLIMVV-VYLRIYVYVKRKTNVLSPHTSGSISRRRTPMKLMK 239
           +YS S Y++   +S   A L ++V +Y+ +++  +     ++     S +R+RT M+   
Sbjct: 179 LYSESTYVILCLISMFFAMLFLLVSLYIHMFLLARTHVKRIAALPGASSARQRTSMQGAV 238

Query: 240 TVMTVLGAFVVCWTPGLVVLLLDGLNCRQ---CG--VQHVKRWFLLLALLNSVVNPIIYS 294
           TV  +LG F VCW P  + L L  L+C Q   C   + H    +L+L + NSV++P+IY+
Sbjct: 239 TVTMLLGVFTVCWAPFFLHLTLM-LSCPQNLYCSRFMSHFNM-YLILIMCNSVMDPLIYA 296

Query: 295 YKDEDMYGTMKKMICC 310
           ++ ++M  T K++ICC
Sbjct: 297 FRSQEMRKTFKEIICC 312


>gi|119508433 melanocortin 4 receptor [Homo sapiens]
          Length = 332

 Score =  114 bits (284), Expect = 2e-25
 Identities = 89/283 (31%), Positives = 151/283 (53%), Gaps = 43/283 (15%)

Query: 48  NSLVIAAVIKNRKFHFPFYYLLANLAAADFFAGIA------YVFLMFNTGPVSKTLTVNR 101
           N LVI A+ KN+  H P Y+ + +LA AD    ++       + L+ +T   +++ TVN 
Sbjct: 62  NILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNI 121

Query: 102 WFLRQGLLDSSLTASLTNLLVIAVERHMSIM-RMRVHSNLTKKRVTLLILLVWAIAIFMG 160
             +   ++ SSL AS+ +LL IAV+R+ +I   ++ H+ +T KRV ++I  +WA      
Sbjct: 122 DNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAA----- 176

Query: 161 AVPTLGWNCLCNISACSSLAPIYSRSYLV-------FWTVSNLMAFLIMVVVYLRIYVYV 213
                     C +S    L  IYS S  V       F+T+  LMA L  V ++L   +++
Sbjct: 177 ----------CTVSGI--LFIIYSDSSAVIICLITMFFTMLALMASLY-VHMFLMARLHI 223

Query: 214 KRKTNVLSPHTSGSISRRRTPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCRQ----- 268
           KR    + P T G+I R+   MK   T+  ++G FVVCW P  + L+   ++C Q     
Sbjct: 224 KRIA--VLPGT-GAI-RQGANMKGAITLTILIGVFVVCWAPFFLHLIFY-ISCPQNPYCV 278

Query: 269 CGVQHVKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKMICCF 311
           C + H    +L+L + NS+++P+IY+ + +++  T K++ICC+
Sbjct: 279 CFMSHFNL-YLILIMCNSIIDPLIYALRSQELRKTFKEIICCY 320


>gi|170671732 melanocortin 3 receptor [Homo sapiens]
          Length = 323

 Score =  103 bits (257), Expect = 2e-22
 Identities = 76/279 (27%), Positives = 136/279 (48%), Gaps = 36/279 (12%)

Query: 48  NSLVIAAVIKNRKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPV-SKTLTVNRWFLR- 105
           N LVI AV++N   H P Y+ L +LA AD    ++          V S  LT    F++ 
Sbjct: 56  NILVILAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQH 115

Query: 106 -QGLLDS----SLTASLTNLLVIAVERHMSIM-RMRVHSNLTKKRVTLLILLVWAIAIFM 159
              + DS    SL AS+ NLL IAV+R+++I   +R HS +T ++   LI+ +W      
Sbjct: 116 MDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWV----- 170

Query: 160 GAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLM--AFLIMVVVYLRIYVYVKRKT 217
                      C +  C  +  +YS S +V   +  +     L+M  +Y+ ++++ +   
Sbjct: 171 ----------CCGV--CGVVFIVYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHV 218

Query: 218 NVLS--PHTSGSISRRRTPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCRQ-----CG 270
             ++  P   G   ++ + MK   T+  +LG F+ CW P  + L+L  + C       C 
Sbjct: 219 KRIAALPPADGVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLI-ITCPTNPYCICY 277

Query: 271 VQHVKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKMIC 309
             H    +L+L + NSV++P+IY+++  ++  T ++++C
Sbjct: 278 TAHFNT-YLVLIMCNSVIDPLIYAFRSLELRNTFREILC 315


>gi|4502929 cannabinoid receptor 2 (macrophage) [Homo sapiens]
          Length = 360

 Score =  100 bits (249), Expect = 2e-21
 Identities = 76/281 (27%), Positives = 138/281 (49%), Gaps = 21/281 (7%)

Query: 31  VIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFHF-PFYYLLANLAAADFFAGIAYV--FLM 87
           V VLC  T   L     N  V+  ++ + +    P Y  + +LA ADF A + +   F+ 
Sbjct: 36  VAVLC--TLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVN 93

Query: 88  FNT--GPVSKTLTVNRWFLRQGLLDSSLTASLTNLLVIAVERHMSIMRMRVHSNL-TKKR 144
           F+   G  SK +    + L+ G +  + TAS+ +LL+ A++R++ +     +  L T+ R
Sbjct: 94  FHVFHGVDSKAV----FLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGR 149

Query: 145 VTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAFLIMVV 204
             + + ++W ++  +  +P +GW C      CS L P+    YL+ W +   +AFL   +
Sbjct: 150 ALVTLGIMWVLSALVSYLPLMGWTCCPR--PCSELFPLIPNDYLLSWLL--FIAFLFSGI 205

Query: 205 VYLRIYVYVKRKTNV--LSPHTSGSI---SRRRTPMKLMKTVMTVLGAFVVCWTPGLVVL 259
           +Y   +V  K   +V  LS H    +   +R R  ++L KT+  VL   ++CW P L ++
Sbjct: 206 IYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALM 265

Query: 260 LLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDM 300
                      V+    +  +L L+NS+VNP+IY+ +  ++
Sbjct: 266 AHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEI 306


>gi|4504533 5-hydroxytryptamine (serotonin) receptor 1B [Homo
           sapiens]
          Length = 390

 Score = 95.9 bits (237), Expect = 5e-20
 Identities = 93/349 (26%), Positives = 151/349 (43%), Gaps = 85/349 (24%)

Query: 31  VIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFHFPFYYLLANLAAADFFAGIAYVFLMFNT 90
           V+++ +     L    SN+ VIA V + RK H P  YL+A+LA  D    I  +      
Sbjct: 50  VLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVM------ 103

Query: 91  GPVSKTLTV-NRWFLRQGLLD-------SSLTASLTNLLVIAVERHMSIM-RMRVHSNLT 141
            P+S   TV  RW L Q + D       +  TAS+ +L VIA++R+ +I   +   +  T
Sbjct: 104 -PISTMYTVTGRWTLGQVVCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRT 162

Query: 142 KKRVTLLILLVWAIAIFMGAVPTLGW---NCLCNISACSSLAPIYSRSYLVFWTVSNLMA 198
            KR  ++I LVW  +I + ++P   W        +S C     + +  ++++   S + A
Sbjct: 163 PKRAAVMIALVWVFSISI-SLPPFFWRQAKAEEEVSEC-----VVNTDHILYTVYSTVGA 216

Query: 199 F----LIMVVVYLRIYVYVKRKTNVLSPHTSGSISRR-------------------RTP- 234
           F    L+++ +Y RIYV  + +    +P+ +G    R                   R P 
Sbjct: 217 FYFPTLLLIALYGRIYVEARSRILKQTPNRTGKRLTRAQLITDSPGSTSSVTSINSRVPD 276

Query: 235 -------------------------MKLM--------KTVMTVLGAFVVCWTPGLVVLLL 261
                                     KLM        KT+  +LGAF+VCW P  ++ L+
Sbjct: 277 VPSESGSPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLV 336

Query: 262 DGLNCRQCGVQH--VKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKMI 308
             + C+     H  +  +F  L  LNS++NPIIY+  +ED      K+I
Sbjct: 337 MPI-CKDACWFHLAIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLI 384


>gi|4501951 adenosine A2b receptor [Homo sapiens]
          Length = 332

 Score = 89.0 bits (219), Expect = 6e-18
 Identities = 80/291 (27%), Positives = 135/291 (46%), Gaps = 40/291 (13%)

Query: 48  NSLVIAAVIKNRKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQG 107
           N LV AAV        P  Y L +LAAAD   G+  +           T      FL   
Sbjct: 25  NVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFAIPFAITISLGFCTDFYGCLFLACF 84

Query: 108 LLDSSLTASLTNLLVIAVERHMSI-MRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLG 166
           +L  +  +S+ +LL +AV+R+++I + +R  S +T  R   +I ++W +A  +G  P LG
Sbjct: 85  VLVLT-QSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRARGVIAVLWVLAFGIGLTPFLG 143

Query: 167 WNC--------------LCNISAC---SSLAPIYSRSYLVFWTVSN--LMAFLIMVVVYL 207
           WN                 N S C        +   SY+V++      L   LIM+V+Y+
Sbjct: 144 WNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIYI 203

Query: 208 RIYVYVKRKTN--VLSPHTSGSISRRRTPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLN 265
           +I++   R+     L  H+  ++ R    +   K++  ++G F +CW P      +  +N
Sbjct: 204 KIFLVACRQLQRTELMDHSRTTLQRE---IHAAKSLAMIVGIFALCWLP------VHAVN 254

Query: 266 C----RQCGVQHVKRWFLLLALL----NSVVNPIIYSYKDEDMYGTMKKMI 308
           C    +    ++  +W + +A+L    NSVVNPI+Y+Y++ D   T  K+I
Sbjct: 255 CVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKII 305


>gi|5921992 adenosine A2a receptor [Homo sapiens]
          Length = 412

 Score = 87.4 bits (215), Expect = 2e-17
 Identities = 78/307 (25%), Positives = 135/307 (43%), Gaps = 41/307 (13%)

Query: 32  IVLCVGTFFCLFIFFSNSLVIAAVIKNRKFHFPFYYLLANLAAADFFAGIAYVFLMFNTG 91
           + + V     +     N LV  AV  N        Y + +LAAAD   G+  +       
Sbjct: 8   VYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI------- 60

Query: 92  PVSKTLTVNRWFLRQGLLDSSL------TASLTNLLVIAVERHMSI-MRMRVHSNLTKKR 144
           P + T++        G L  +        +S+ +LL IA++R+++I + +R +  +T  R
Sbjct: 61  PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR 120

Query: 145 VTLLILLVWAIAIFMGAVPTLGWN--------------CLCNISACSSLAPIYSRSYLVF 190
              +I + W ++  +G  P LGWN              C     AC     +   +Y+V+
Sbjct: 121 AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACL-FEDVVPMNYMVY 179

Query: 191 WT--VSNLMAFLIMVVVYLRIYVYVKRKTNVLSPHTSGSISRRRTPMKLM---KTVMTVL 245
           +      L+  L+M+ VYLRI++  +R+   +          R T  K +   K++  ++
Sbjct: 180 FNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIV 239

Query: 246 GAFVVCWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALL----NSVVNPIIYSYKDEDMY 301
           G F +CW P L ++      C  C   H   W + LA++    NSVVNP IY+Y+  +  
Sbjct: 240 GLFALCWLP-LHIINCFTFFCPDCS--HAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFR 296

Query: 302 GTMKKMI 308
            T +K+I
Sbjct: 297 QTFRKII 303


>gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]
          Length = 520

 Score = 82.8 bits (203), Expect = 4e-16
 Identities = 86/356 (24%), Positives = 140/356 (39%), Gaps = 60/356 (16%)

Query: 17  SNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFHFPFYYLLANLAAAD 76
           S+  T+     T+ + V  V   F LF    N LVI +V  NR    P  Y + NLA AD
Sbjct: 32  SSNSTLPQLDITRAISVGLVLGAFILFAIVGNILVILSVACNRHLRTPTNYFIVNLAMAD 91

Query: 77  FFAGIAYVFLMFNTGPVSKTLTV-NRWFLRQGLLD-------SSLTASLTNLLVIAVERH 128
                  + L F   P S  L V   W L +   D          TAS+ +L  I+++R+
Sbjct: 92  -------LLLSFTVLPFSAALEVLGYWVLGRIFCDIWAAVDVLCCTASILSLCAISIDRY 144

Query: 129 MSI-MRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWN--CLCNISACSSLAPIYSR 185
           + +   ++  + +T+++  L +L VW ++  +   P LGW      +   C      +  
Sbjct: 145 IGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPLLGWKEPAPNDDKECGVTEEPF-- 202

Query: 186 SYLVFWTVSNL-MAFLIMVVVYLRIYVYVKRKTNVL------------------------ 220
            Y +F ++ +  +   +++V+Y R+Y+  KR T  L                        
Sbjct: 203 -YALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKELTLRIHSKNFH 261

Query: 221 -----SPHTSGSISRRRTPMKLM---------KTVMTVLGAFVVCWTPGLVVLLLDGLNC 266
                S    G   R    +KL          KT+  V+G F++CW P  + L L  L  
Sbjct: 262 EDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPFFIALPLGSLFS 321

Query: 267 RQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKMICCFSQENPERRPSR 322
                  V +    L   NS +NPIIY    ++      +++ C  +    RR  R
Sbjct: 322 TLKPPDAVFKVVFWLGYFNSCLNPIIYPCSSKEFKRAFVRILGCQCRGRGRRRRRR 377


>gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens]
          Length = 388

 Score = 82.4 bits (202), Expect = 6e-16
 Identities = 92/369 (24%), Positives = 161/369 (43%), Gaps = 49/369 (13%)

Query: 17  SNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFH-FPFYYLLANLAAA 75
           +N  + + +   + V++L   +   L     N LV+ AV  +R+       Y + +LA A
Sbjct: 6   ANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFA 65

Query: 76  DFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQG--LLDSSL-----TASLTNLLVIAVERH 128
           D    +    L+   G +   L  + W   +   L+ +SL     TAS+ +L  I+++R+
Sbjct: 66  DLLVSV----LVMPFGAIE--LVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRY 119

Query: 129 MSI--MRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTL-GWNCLCNISACSS--LAPIY 183
            +I    +   + +T  R+ L++   W I  F+  +P + GWN +  I            
Sbjct: 120 YAICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNS 179

Query: 184 SRSYLVFWT----------VSNLMAFLIMVVVYLRIYVYVKRKTNVLS------------ 221
           + +Y VF            V+  + FL+MV+ Y RIYV  K   + +             
Sbjct: 180 NSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESR 239

Query: 222 PHTSG--SISRRRTPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVKRWFL 279
           P ++   S  R RT  K  KT+  ++G F +CW P  V  ++D         Q V   FL
Sbjct: 240 PQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQ-VWTAFL 298

Query: 280 LLALLNSVVNPIIYSYKDEDMYGTMKKMICCFSQENPERRPSRIPSTVLSRSDT--GSQY 337
            L  +NS +NP +Y++ ++        ++CC   +   RRPS +  TV   + T  GS +
Sbjct: 299 WLGYINSGLNPFLYAFLNKSFRRAFLIILCC--DDERYRRPSILGQTVPCSTTTINGSTH 356

Query: 338 I-EDSISQG 345
           +  D++  G
Sbjct: 357 VLRDAVECG 365


>gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]
          Length = 359

 Score = 82.0 bits (201), Expect = 7e-16
 Identities = 90/361 (24%), Positives = 157/361 (43%), Gaps = 48/361 (13%)

Query: 17  SNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFH-FPFYYLLANLAAA 75
           +N  + + +   + V++L   +   L     N LV+ AV  +R+       Y + +LA A
Sbjct: 6   ANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFA 65

Query: 76  DFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQG--LLDSSL-----TASLTNLLVIAVERH 128
           D    +    L+   G +   L  + W   +   L+ +SL     TAS+ +L  I+++R+
Sbjct: 66  DLLVSV----LVMPFGAIE--LVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRY 119

Query: 129 MSI--MRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTL-GWNCLCNISACSS--LAPIY 183
            +I    +   + +T  R+ L++   W I  F+  +P + GWN +  I            
Sbjct: 120 YAICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNS 179

Query: 184 SRSYLVFWT----------VSNLMAFLIMVVVYLRIYVYVKRKTNVLS------------ 221
           + +Y VF            V+  + FL+MV+ Y RIYV  K   + +             
Sbjct: 180 NSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESR 239

Query: 222 PHTSG--SISRRRTPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVKRWFL 279
           P ++   S  R RT  K  KT+  ++G F +CW P  V  ++D         Q V   FL
Sbjct: 240 PQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQ-VWTAFL 298

Query: 280 LLALLNSVVNPIIYSYKDEDMYGTMKKMICCFSQENPERRPSRIPSTVLSRSDT--GSQY 337
            L  +NS +NP +Y++ ++        ++CC   +   RRPS +  TV   + T  GS +
Sbjct: 299 WLGYINSGLNPFLYAFLNKSFRRAFLIILCC--DDERYRRPSILGQTVPCSTTTINGSTH 356

Query: 338 I 338
           +
Sbjct: 357 V 357


>gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]
          Length = 428

 Score = 82.0 bits (201), Expect = 7e-16
 Identities = 90/361 (24%), Positives = 157/361 (43%), Gaps = 48/361 (13%)

Query: 17  SNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFH-FPFYYLLANLAAA 75
           +N  + + +   + V++L   +   L     N LV+ AV  +R+       Y + +LA A
Sbjct: 6   ANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFA 65

Query: 76  DFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQG--LLDSSL-----TASLTNLLVIAVERH 128
           D    +    L+   G +   L  + W   +   L+ +SL     TAS+ +L  I+++R+
Sbjct: 66  DLLVSV----LVMPFGAIE--LVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRY 119

Query: 129 MSI--MRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTL-GWNCLCNISACSS--LAPIY 183
            +I    +   + +T  R+ L++   W I  F+  +P + GWN +  I            
Sbjct: 120 YAICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNS 179

Query: 184 SRSYLVFWT----------VSNLMAFLIMVVVYLRIYVYVKRKTNVLS------------ 221
           + +Y VF            V+  + FL+MV+ Y RIYV  K   + +             
Sbjct: 180 NSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESR 239

Query: 222 PHTSG--SISRRRTPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVKRWFL 279
           P ++   S  R RT  K  KT+  ++G F +CW P  V  ++D         Q V   FL
Sbjct: 240 PQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQ-VWTAFL 298

Query: 280 LLALLNSVVNPIIYSYKDEDMYGTMKKMICCFSQENPERRPSRIPSTVLSRSDT--GSQY 337
            L  +NS +NP +Y++ ++        ++CC   +   RRPS +  TV   + T  GS +
Sbjct: 299 WLGYINSGLNPFLYAFLNKSFRRAFLIILCC--DDERYRRPSILGQTVPCSTTTINGSTH 356

Query: 338 I 338
           +
Sbjct: 357 V 357


>gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens]
          Length = 360

 Score = 82.0 bits (201), Expect = 7e-16
 Identities = 90/361 (24%), Positives = 157/361 (43%), Gaps = 48/361 (13%)

Query: 17  SNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFH-FPFYYLLANLAAA 75
           +N  + + +   + V++L   +   L     N LV+ AV  +R+       Y + +LA A
Sbjct: 6   ANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFA 65

Query: 76  DFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQG--LLDSSL-----TASLTNLLVIAVERH 128
           D    +    L+   G +   L  + W   +   L+ +SL     TAS+ +L  I+++R+
Sbjct: 66  DLLVSV----LVMPFGAIE--LVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRY 119

Query: 129 MSI--MRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTL-GWNCLCNISACSS--LAPIY 183
            +I    +   + +T  R+ L++   W I  F+  +P + GWN +  I            
Sbjct: 120 YAICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNS 179

Query: 184 SRSYLVFWT----------VSNLMAFLIMVVVYLRIYVYVKRKTNVLS------------ 221
           + +Y VF            V+  + FL+MV+ Y RIYV  K   + +             
Sbjct: 180 NSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESR 239

Query: 222 PHTSG--SISRRRTPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVKRWFL 279
           P ++   S  R RT  K  KT+  ++G F +CW P  V  ++D         Q V   FL
Sbjct: 240 PQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQ-VWTAFL 298

Query: 280 LLALLNSVVNPIIYSYKDEDMYGTMKKMICCFSQENPERRPSRIPSTVLSRSDT--GSQY 337
            L  +NS +NP +Y++ ++        ++CC   +   RRPS +  TV   + T  GS +
Sbjct: 299 WLGYINSGLNPFLYAFLNKSFRRAFLIILCC--DDERYRRPSILGQTVPCSTTTINGSTH 356

Query: 338 I 338
           +
Sbjct: 357 V 357


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.329    0.138    0.434 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,892,188
Number of Sequences: 37866
Number of extensions: 469311
Number of successful extensions: 2772
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 222
Number of HSP's successfully gapped in prelim test: 344
Number of HSP's that attempted gapping in prelim test: 1928
Number of HSP's gapped (non-prelim): 727
length of query: 353
length of database: 18,247,518
effective HSP length: 103
effective length of query: 250
effective length of database: 14,347,320
effective search space: 3586830000
effective search space used: 3586830000
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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