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Search of human proteins with 68303565
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|68303565 proteasome alpha 8 subunit isoform 3 [Homo sapiens]
(212 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|68303565 proteasome alpha 8 subunit isoform 3 [Homo sapiens] 411 e-115
gi|68303563 proteasome alpha 8 subunit isoform 2 [Homo sapiens] 392 e-110
gi|68303561 proteasome alpha 8 subunit isoform 1 [Homo sapiens] 390 e-109
gi|4506189 proteasome alpha 7 subunit [Homo sapiens] 330 7e-91
gi|156713442 proteasome alpha 4 subunit isoform 1 [Homo sapiens] 137 7e-33
gi|4506185 proteasome alpha 4 subunit isoform 1 [Homo sapiens] 137 7e-33
gi|23110942 proteasome alpha 5 subunit [Homo sapiens] 120 1e-27
gi|156713444 proteasome alpha 4 subunit isoform 2 [Homo sapiens] 116 1e-26
gi|4506181 proteasome subunit alpha type 2 [Homo sapiens] 114 5e-26
gi|4506179 proteasome alpha 1 subunit isoform 2 [Homo sapiens] 113 1e-25
gi|23110935 proteasome alpha 1 subunit isoform 1 [Homo sapiens] 113 1e-25
gi|23110944 proteasome alpha 6 subunit [Homo sapiens] 92 2e-19
gi|4506183 proteasome alpha 3 subunit isoform 1 [Homo sapiens] 81 7e-16
gi|23110939 proteasome alpha 3 subunit isoform 2 [Homo sapiens] 77 1e-14
gi|221316716 proteasome alpha 1 subunit isoform 3 [Homo sapiens] 57 2e-08
gi|169206322 PREDICTED: similar to hCG30646 [Homo sapiens] 43 2e-04
gi|239750562 PREDICTED: similar to hCG30646 [Homo sapiens] 43 2e-04
gi|239744861 PREDICTED: similar to hCG30646 [Homo sapiens] 43 2e-04
gi|70980531 GGA binding partner [Homo sapiens] 34 0.080
gi|4506191 proteasome beta 10 subunit proprotein [Homo sapiens] 33 0.14
gi|4506193 proteasome beta 1 subunit [Homo sapiens] 32 0.30
gi|23110932 proteasome beta 9 subunit isoform 2 proprotein [Homo... 29 2.6
gi|4506205 proteasome beta 9 subunit isoform 1 proprotein [Homo ... 29 2.6
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 29 2.6
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 29 3.4
gi|71773415 annexin VI isoform 2 [Homo sapiens] 29 3.4
gi|71773329 annexin VI isoform 1 [Homo sapiens] 29 3.4
gi|109255234 centrosomal protein 290kDa [Homo sapiens] 28 4.4
gi|4506411 Ran GTPase activating protein 1 [Homo sapiens] 28 4.4
gi|95089461 discs large homolog 5 [Homo sapiens] 28 5.7
>gi|68303565 proteasome alpha 8 subunit isoform 3 [Homo sapiens]
Length = 212
Score = 411 bits (1057), Expect = e-115
Identities = 212/212 (100%), Positives = 212/212 (100%)
Query: 1 MASRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRGLTADARVVINRARVECQSHKL 60
MASRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRGLTADARVVINRARVECQSHKL
Sbjct: 1 MASRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRGLTADARVVINRARVECQSHKL 60
Query: 61 TVEDPVTVEYITRFIATLKQKYTQSNGRRPFGISALIVGFDDDGISRLYQTDPSGTYHAW 120
TVEDPVTVEYITRFIATLKQKYTQSNGRRPFGISALIVGFDDDGISRLYQTDPSGTYHAW
Sbjct: 61 TVEDPVTVEYITRFIATLKQKYTQSNGRRPFGISALIVGFDDDGISRLYQTDPSGTYHAW 120
Query: 121 KANAIGRSAKTVREFLEKNYTEDAIASDSEAIKLAIKALLEVVQSGGKNIELAIIRRNQP 180
KANAIGRSAKTVREFLEKNYTEDAIASDSEAIKLAIKALLEVVQSGGKNIELAIIRRNQP
Sbjct: 121 KANAIGRSAKTVREFLEKNYTEDAIASDSEAIKLAIKALLEVVQSGGKNIELAIIRRNQP 180
Query: 181 LKMFSAKEVELYVTEIEKEKEEAEKKKSKKSV 212
LKMFSAKEVELYVTEIEKEKEEAEKKKSKKSV
Sbjct: 181 LKMFSAKEVELYVTEIEKEKEEAEKKKSKKSV 212
>gi|68303563 proteasome alpha 8 subunit isoform 2 [Homo sapiens]
Length = 250
Score = 392 bits (1008), Expect = e-110
Identities = 212/250 (84%), Positives = 212/250 (84%), Gaps = 38/250 (15%)
Query: 1 MASRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRG--------------------- 39
MASRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRG
Sbjct: 1 MASRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRGTNIVVLGVEKKSVAKLQDERT 60
Query: 40 -----------------LTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQKY 82
LTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQKY
Sbjct: 61 VRKICALDDHVCMAFAGLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQKY 120
Query: 83 TQSNGRRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYTE 142
TQSNGRRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYTE
Sbjct: 121 TQSNGRRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYTE 180
Query: 143 DAIASDSEAIKLAIKALLEVVQSGGKNIELAIIRRNQPLKMFSAKEVELYVTEIEKEKEE 202
DAIASDSEAIKLAIKALLEVVQSGGKNIELAIIRRNQPLKMFSAKEVELYVTEIEKEKEE
Sbjct: 181 DAIASDSEAIKLAIKALLEVVQSGGKNIELAIIRRNQPLKMFSAKEVELYVTEIEKEKEE 240
Query: 203 AEKKKSKKSV 212
AEKKKSKKSV
Sbjct: 241 AEKKKSKKSV 250
>gi|68303561 proteasome alpha 8 subunit isoform 1 [Homo sapiens]
Length = 256
Score = 390 bits (1002), Expect = e-109
Identities = 212/256 (82%), Positives = 212/256 (82%), Gaps = 44/256 (17%)
Query: 1 MASRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRG--------------------- 39
MASRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRG
Sbjct: 1 MASRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRGTNIVVLGVEKKSVAKLQDERT 60
Query: 40 -----------------------LTADARVVINRARVECQSHKLTVEDPVTVEYITRFIA 76
LTADARVVINRARVECQSHKLTVEDPVTVEYITRFIA
Sbjct: 61 VRKICALDDHVCMAFAVLTIFIGLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIA 120
Query: 77 TLKQKYTQSNGRRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFL 136
TLKQKYTQSNGRRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFL
Sbjct: 121 TLKQKYTQSNGRRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFL 180
Query: 137 EKNYTEDAIASDSEAIKLAIKALLEVVQSGGKNIELAIIRRNQPLKMFSAKEVELYVTEI 196
EKNYTEDAIASDSEAIKLAIKALLEVVQSGGKNIELAIIRRNQPLKMFSAKEVELYVTEI
Sbjct: 181 EKNYTEDAIASDSEAIKLAIKALLEVVQSGGKNIELAIIRRNQPLKMFSAKEVELYVTEI 240
Query: 197 EKEKEEAEKKKSKKSV 212
EKEKEEAEKKKSKKSV
Sbjct: 241 EKEKEEAEKKKSKKSV 256
>gi|4506189 proteasome alpha 7 subunit [Homo sapiens]
Length = 248
Score = 330 bits (845), Expect = 7e-91
Identities = 173/245 (70%), Positives = 191/245 (77%), Gaps = 38/245 (15%)
Query: 5 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRG------------------------- 39
YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVG+RG
Sbjct: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVRKI 62
Query: 40 -------------LTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQKYTQSN 86
LTADAR+VINRARVECQSH+LTVEDPVTVEYITR+IA+LKQ+YTQSN
Sbjct: 63 CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122
Query: 87 GRRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYTEDAIA 146
GRRPFGISALIVGFD DG RLYQTDPSGTYHAWKANAIGR AK+VREFLEKNYT++AI
Sbjct: 123 GRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDEAIE 182
Query: 147 SDSEAIKLAIKALLEVVQSGGKNIELAIIRRNQPLKMFSAKEVELYVTEIEKEKEEAEKK 206
+D IKL IKALLEVVQSGGKNIELA++RR+Q LK+ + +E+E YV EIEKEKEE EKK
Sbjct: 183 TDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQSLKILNPEEIEKYVAEIEKEKEENEKK 242
Query: 207 KSKKS 211
K KK+
Sbjct: 243 KQKKA 247
>gi|156713442 proteasome alpha 4 subunit isoform 1 [Homo sapiens]
Length = 261
Score = 137 bits (345), Expect = 7e-33
Identities = 82/255 (32%), Positives = 130/255 (50%), Gaps = 46/255 (18%)
Query: 1 MASRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGI----------------------- 37
M+ RYD T+FSP+G L+QVEYA EA+ T +GI
Sbjct: 1 MSRRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVF 60
Query: 38 ----------------RGLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQK 81
G+T+DA V+ N R+ Q + L ++P+ E + + +KQ
Sbjct: 61 FSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQA 120
Query: 82 YTQSNGRRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYT 141
YTQ G+RPFG+S L +G+D +LYQ+DPSG Y WKA IG ++ L+++Y
Sbjct: 121 YTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYK 180
Query: 142 EDAIASDSEAIKLAIKAL---LEVVQSGGKNIELAIIRRNQ---PLKMFSAKEVELYVTE 195
E + S A+ LAIK L ++V + + +E+A + R +++ KEVE + +
Sbjct: 181 EGEMTLKS-ALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKK 239
Query: 196 IEKEKEEAEKKKSKK 210
E+E+ +AE++K +K
Sbjct: 240 HEEEEAKAEREKKEK 254
>gi|4506185 proteasome alpha 4 subunit isoform 1 [Homo sapiens]
Length = 261
Score = 137 bits (345), Expect = 7e-33
Identities = 82/255 (32%), Positives = 130/255 (50%), Gaps = 46/255 (18%)
Query: 1 MASRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGI----------------------- 37
M+ RYD T+FSP+G L+QVEYA EA+ T +GI
Sbjct: 1 MSRRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVF 60
Query: 38 ----------------RGLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQK 81
G+T+DA V+ N R+ Q + L ++P+ E + + +KQ
Sbjct: 61 FSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQA 120
Query: 82 YTQSNGRRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYT 141
YTQ G+RPFG+S L +G+D +LYQ+DPSG Y WKA IG ++ L+++Y
Sbjct: 121 YTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYK 180
Query: 142 EDAIASDSEAIKLAIKAL---LEVVQSGGKNIELAIIRRNQ---PLKMFSAKEVELYVTE 195
E + S A+ LAIK L ++V + + +E+A + R +++ KEVE + +
Sbjct: 181 EGEMTLKS-ALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKK 239
Query: 196 IEKEKEEAEKKKSKK 210
E+E+ +AE++K +K
Sbjct: 240 HEEEEAKAEREKKEK 254
>gi|23110942 proteasome alpha 5 subunit [Homo sapiens]
Length = 241
Score = 120 bits (300), Expect = 1e-27
Identities = 79/239 (33%), Positives = 124/239 (51%), Gaps = 48/239 (20%)
Query: 3 SRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIR------------------------ 38
S YDR + FSP+G LFQVEYA EA+K GSTA+GI+
Sbjct: 6 SEYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLMEPSSIE 65
Query: 39 --------------GLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQKYTQ 84
GL ADA+ +I++ARVE Q+H T + +TVE +T+ ++ L ++ +
Sbjct: 66 KIVEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLALQFGE 125
Query: 85 SNG-----RRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKN 139
+ RPFG++ L G D+ G +L+ DPSGT+ A AIG +++ + L++
Sbjct: 126 EDADPGAMSRPFGVALLFGGVDEKG-PQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEV 184
Query: 140 YTEDAIASDSEAIKLAIKALLEVVQS--GGKNIELAIIRRNQPLKMFSAKEVELYVTEI 196
Y + EAIK ++ L +V++ NIELA ++ Q MF+ +E+E + +I
Sbjct: 185 YHKSMTL--KEAIKSSLIILKQVMEEKLNATNIELATVQPGQNFHMFTKEELEEVIKDI 241
>gi|156713444 proteasome alpha 4 subunit isoform 2 [Homo sapiens]
Length = 190
Score = 116 bits (291), Expect = 1e-26
Identities = 63/183 (34%), Positives = 106/183 (57%), Gaps = 7/183 (3%)
Query: 34 AVGIRGLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQKYTQSNGRRPFGI 93
A + G+T+DA V+ N R+ Q + L ++P+ E + + +KQ YTQ G+RPFG+
Sbjct: 2 ACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGV 61
Query: 94 SALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYTEDAIASDSEAIK 153
S L +G+D +LYQ+DPSG Y WKA IG ++ L+++Y E + S A+
Sbjct: 62 SLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKS-ALA 120
Query: 154 LAIKAL---LEVVQSGGKNIELAIIRRNQ---PLKMFSAKEVELYVTEIEKEKEEAEKKK 207
LAIK L ++V + + +E+A + R +++ KEVE + + E+E+ +AE++K
Sbjct: 121 LAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREK 180
Query: 208 SKK 210
+K
Sbjct: 181 KEK 183
>gi|4506181 proteasome subunit alpha type 2 [Homo sapiens]
Length = 234
Score = 114 bits (286), Expect = 5e-26
Identities = 82/237 (34%), Positives = 117/237 (49%), Gaps = 45/237 (18%)
Query: 1 MASR-YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIR--------------------- 38
MA R Y ++T FSP G L Q+EYA AV G+ +VGI+
Sbjct: 1 MAERGYSFSLTTFSPSGKLVQIEYALAAVAGGAPSVGIKAANGVVLATEKKQKSILYDER 60
Query: 39 -----------------GLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQK 81
G+ D RV+++RAR Q + L ++P+ + + +A++ Q+
Sbjct: 61 SVHKVEPITKHIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQE 120
Query: 82 YTQSNGRRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYT 141
YTQS G RPFG+S LI G+ ++G L+Q+DPSG Y AWKA A+G++ + FLEK Y
Sbjct: 121 YTQSGGVRPFGVSLLICGW-NEGRPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYN 179
Query: 142 EDAIASDSEAIKLAIKALLEVV--QSGGKNIELAIIRRNQPLKMFSAKEVELYVTEI 196
ED D AI AI L E Q NIE+ I + + EV+ Y+ I
Sbjct: 180 EDLELED--AIHTAILTLKESFEGQMTEDNIEVGIC-NEAGFRRLTPTEVKDYLAAI 233
>gi|4506179 proteasome alpha 1 subunit isoform 2 [Homo sapiens]
Length = 263
Score = 113 bits (283), Expect = 1e-25
Identities = 69/239 (28%), Positives = 119/239 (49%), Gaps = 41/239 (17%)
Query: 3 SRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIR------------------------ 38
++YD +TV+SP G + Q+EYA EAVK+GS VG++
Sbjct: 4 NQYDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQKKI 63
Query: 39 ------------GLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQKYTQSN 86
GLTADAR++ N R EC + + P+ V + I + Q TQ
Sbjct: 64 LHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRY 123
Query: 87 GRRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYTEDAIA 146
GRRP+G+ LI G+DD G ++QT PS Y +A +IG +++ R +LE++ +E
Sbjct: 124 GRRPYGVGLLIAGYDDMG-PHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFMEC 182
Query: 147 SDSEAIKLAIKALLEVVQS----GGKNIELAIIRRNQPLKMFSAKEVELYVTEIEKEKE 201
+ +E +K ++AL E + + KN+ + I+ ++ ++ +V ++ +E+ +
Sbjct: 183 NLNELVKHGLRALRETLPAEQDLTTKNVSIGIVGKDLEFTIYDDDDVSPFLEGLEERPQ 241
>gi|23110935 proteasome alpha 1 subunit isoform 1 [Homo sapiens]
Length = 269
Score = 113 bits (283), Expect = 1e-25
Identities = 69/239 (28%), Positives = 119/239 (49%), Gaps = 41/239 (17%)
Query: 3 SRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIR------------------------ 38
++YD +TV+SP G + Q+EYA EAVK+GS VG++
Sbjct: 10 NQYDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQKKI 69
Query: 39 ------------GLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQKYTQSN 86
GLTADAR++ N R EC + + P+ V + I + Q TQ
Sbjct: 70 LHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRY 129
Query: 87 GRRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYTEDAIA 146
GRRP+G+ LI G+DD G ++QT PS Y +A +IG +++ R +LE++ +E
Sbjct: 130 GRRPYGVGLLIAGYDDMG-PHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFMEC 188
Query: 147 SDSEAIKLAIKALLEVVQS----GGKNIELAIIRRNQPLKMFSAKEVELYVTEIEKEKE 201
+ +E +K ++AL E + + KN+ + I+ ++ ++ +V ++ +E+ +
Sbjct: 189 NLNELVKHGLRALRETLPAEQDLTTKNVSIGIVGKDLEFTIYDDDDVSPFLEGLEERPQ 247
>gi|23110944 proteasome alpha 6 subunit [Homo sapiens]
Length = 246
Score = 92.4 bits (228), Expect = 2e-19
Identities = 63/234 (26%), Positives = 109/234 (46%), Gaps = 42/234 (17%)
Query: 5 YDRAITVFSPDGHLFQVEYAQEAVKKGS-TAVGIRG------------------------ 39
+DR IT+FSP+G L+QVEYA +A+ +G T+V +RG
Sbjct: 9 FDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTH 68
Query: 40 --------------LTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQKYTQS 85
+TAD+R + RAR E + K + V+ + + IA + Q YTQ+
Sbjct: 69 LFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQN 128
Query: 86 NGRRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYTEDAI 145
RP G +++G D++ ++Y+ DP+G Y +KA A G FLEK +
Sbjct: 129 AEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFD 188
Query: 146 ASDSEAIKLAIKALLEVVQSGGK--NIELAIIR-RNQPLKMFSAKEVELYVTEI 196
+ + ++ AI L V+ K IE+ ++ N ++ + E++ ++ +
Sbjct: 189 WTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLVAL 242
>gi|4506183 proteasome alpha 3 subunit isoform 1 [Homo sapiens]
Length = 255
Score = 80.9 bits (198), Expect = 7e-16
Identities = 64/245 (26%), Positives = 111/245 (45%), Gaps = 46/245 (18%)
Query: 5 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIR-------------------------- 38
YD + + FSPDG +FQVEYA +AV+ STA+GIR
Sbjct: 8 YDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRL 67
Query: 39 ------------GLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQKYTQSN 86
GL ADAR + + AR E + + + ++++ +A YT +
Sbjct: 68 FNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYS 127
Query: 87 GRRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYTEDAIA 146
RPFG S ++ + + ++LY DPSG + + AIG++ + + +EK ++
Sbjct: 128 AVRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKEMTC 187
Query: 147 SD--SEAIKLAIKALLEVVQSGGKNIELAII-----RRNQPLKMFSAKEVELYVTEIEKE 199
D E K+ I + + V+ +EL+ + R++ + +E E Y E KE
Sbjct: 188 RDIVKEVAKI-IYIVHDEVKDKAFELELSWVGELTNGRHEIVPKDIREEAEKYAKESLKE 246
Query: 200 KEEAE 204
++E++
Sbjct: 247 EDESD 251
>gi|23110939 proteasome alpha 3 subunit isoform 2 [Homo sapiens]
Length = 248
Score = 76.6 bits (187), Expect = 1e-14
Identities = 66/245 (26%), Positives = 110/245 (44%), Gaps = 53/245 (21%)
Query: 5 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIR-------------------------- 38
YD + + FSPDG +FQVEYA +AV+ STA+GIR
Sbjct: 8 YDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRL 67
Query: 39 ------------GLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQKYTQSN 86
GL ADAR + + AR E + + + ++++ +A YT +
Sbjct: 68 FNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYS 127
Query: 87 GRRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYTEDAIA 146
RPFG S +DG ++LY DPSG + + AIG++ + + +EK ++
Sbjct: 128 AVRPFGCSV------NDG-AQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKEMTC 180
Query: 147 SD--SEAIKLAIKALLEVVQSGGKNIELAII-----RRNQPLKMFSAKEVELYVTEIEKE 199
D E K+ I + + V+ +EL+ + R++ + +E E Y E KE
Sbjct: 181 RDIVKEVAKI-IYIVHDEVKDKAFELELSWVGELTNGRHEIVPKDIREEAEKYAKESLKE 239
Query: 200 KEEAE 204
++E++
Sbjct: 240 EDESD 244
>gi|221316716 proteasome alpha 1 subunit isoform 3 [Homo sapiens]
Length = 130
Score = 56.6 bits (135), Expect = 2e-08
Identities = 25/57 (43%), Positives = 38/57 (66%)
Query: 3 SRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRGLTADARVVINRARVECQSHK 59
++YD +TV+SP G + Q+EYA EAVK+GS VG++ T V + RA+ E +H+
Sbjct: 4 NQYDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQ 60
>gi|169206322 PREDICTED: similar to hCG30646 [Homo sapiens]
Length = 272
Score = 43.1 bits (100), Expect = 2e-04
Identities = 38/141 (26%), Positives = 66/141 (46%), Gaps = 17/141 (12%)
Query: 5 YDRAITVFSPDGHLFQVEYAQEAVKKGS-TAVGIRGLTADARVVINRARV-----ECQSH 58
+DR + +FSP L+QV+YA +A+ +G T+V +R D V++ V + ++H
Sbjct: 93 FDRHLIIFSPKVQLYQVQYAFKAINQGGLTSVAVR--KKDCAVIVTHKIVPDKLLDSRTH 150
Query: 59 --KLTVEDPVTVEYITRFIATLKQKYTQSNGRRPFGISALIVGFDDDGISRLYQTDPSGT 116
K+T + +T + +Q+ + I F++ G R+Y+ D +G
Sbjct: 151 LFKMTKNTGRVITGVTADSRSREQRAQYKAANCKYNI------FEELG-PRVYKCDAAGY 203
Query: 117 YHAWKANAIGRSAKTVREFLE 137
Y +KA A G FLE
Sbjct: 204 YCGFKATAAGVKQAESTSFLE 224
>gi|239750562 PREDICTED: similar to hCG30646 [Homo sapiens]
Length = 272
Score = 43.1 bits (100), Expect = 2e-04
Identities = 38/141 (26%), Positives = 66/141 (46%), Gaps = 17/141 (12%)
Query: 5 YDRAITVFSPDGHLFQVEYAQEAVKKGS-TAVGIRGLTADARVVINRARV-----ECQSH 58
+DR + +FSP L+QV+YA +A+ +G T+V +R D V++ V + ++H
Sbjct: 93 FDRHLIIFSPKVQLYQVQYAFKAINQGGLTSVAVR--KKDCAVIVTHKIVPDKLLDSRTH 150
Query: 59 --KLTVEDPVTVEYITRFIATLKQKYTQSNGRRPFGISALIVGFDDDGISRLYQTDPSGT 116
K+T + +T + +Q+ + I F++ G R+Y+ D +G
Sbjct: 151 LFKMTKNTGRVITGVTADSRSREQRAQYKAANCKYNI------FEELG-PRVYKCDAAGY 203
Query: 117 YHAWKANAIGRSAKTVREFLE 137
Y +KA A G FLE
Sbjct: 204 YCGFKATAAGVKQAESTSFLE 224
>gi|239744861 PREDICTED: similar to hCG30646 [Homo sapiens]
Length = 272
Score = 43.1 bits (100), Expect = 2e-04
Identities = 38/141 (26%), Positives = 66/141 (46%), Gaps = 17/141 (12%)
Query: 5 YDRAITVFSPDGHLFQVEYAQEAVKKGS-TAVGIRGLTADARVVINRARV-----ECQSH 58
+DR + +FSP L+QV+YA +A+ +G T+V +R D V++ V + ++H
Sbjct: 93 FDRHLIIFSPKVQLYQVQYAFKAINQGGLTSVAVR--KKDCAVIVTHKIVPDKLLDSRTH 150
Query: 59 --KLTVEDPVTVEYITRFIATLKQKYTQSNGRRPFGISALIVGFDDDGISRLYQTDPSGT 116
K+T + +T + +Q+ + I F++ G R+Y+ D +G
Sbjct: 151 LFKMTKNTGRVITGVTADSRSREQRAQYKAANCKYNI------FEELG-PRVYKCDAAGY 203
Query: 117 YHAWKANAIGRSAKTVREFLE 137
Y +KA A G FLE
Sbjct: 204 YCGFKATAAGVKQAESTSFLE 224
>gi|70980531 GGA binding partner [Homo sapiens]
Length = 441
Score = 34.3 bits (77), Expect = 0.080
Identities = 25/77 (32%), Positives = 45/77 (58%), Gaps = 2/77 (2%)
Query: 137 EKNYTEDAIASDSEAIKLAIK-ALLEVVQSGGKNIELAIIRRNQPLKMFSAKEVELYVTE 195
E+ ++A+ S ++ K A+K A+L+VV+ KN+E A + K AK+ E E
Sbjct: 295 ERQRNKEALVSAAKLEKEAVKDAVLKVVEEERKNLEKAHAEERELWKTEHAKDQEKVSQE 354
Query: 196 IEKEKEEAEKKKSKKSV 212
I+K +E ++K S+++V
Sbjct: 355 IQKAIQE-QRKISQETV 370
>gi|4506191 proteasome beta 10 subunit proprotein [Homo sapiens]
Length = 273
Score = 33.5 bits (75), Expect = 0.14
Identities = 32/141 (22%), Positives = 56/141 (39%), Gaps = 9/141 (6%)
Query: 39 GLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQKYTQSNGRRPFGISALIV 98
G+ ADA + + + H L+ V +TR + +Y G ++LIV
Sbjct: 86 GVAADAEMTTRMVASKMELHALSTGREPRVATVTRILRQTLFRYQGHVG------ASLIV 139
Query: 99 GFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYTEDAI--ASDSEAIKLAI 156
G D +LY P G+Y A+G LE + + A+ ++
Sbjct: 140 GGVDLTGPQLYGVHPHGSYSRLPFTALGSGQDAALAVLEDRFQPNMTLEAAQGLLVEAVT 199
Query: 157 KALLEVVQSGGKNIELAIIRR 177
+L + SGG N++ +I +
Sbjct: 200 AGILGDLGSGG-NVDACVITK 219
>gi|4506193 proteasome beta 1 subunit [Homo sapiens]
Length = 241
Score = 32.3 bits (72), Expect = 0.30
Identities = 22/105 (20%), Positives = 43/105 (40%), Gaps = 4/105 (3%)
Query: 33 TAVGIRGLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQKYTQSNGRRPFG 92
T +G G D + + +K + +T I ++T+ S P+
Sbjct: 78 TVIGCSGFHGDCLTLTKIIEARLKMYKHSNNKAMTTGAIAAMLSTI----LYSRRFFPYY 133
Query: 93 ISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLE 137
+ +I G D++G +Y DP G+Y A G ++ ++ L+
Sbjct: 134 VYNIIGGLDEEGKGAVYSFDPVGSYQRDSFKAGGSASAMLQPLLD 178
>gi|23110932 proteasome beta 9 subunit isoform 2 proprotein [Homo
sapiens]
Length = 209
Score = 29.3 bits (64), Expect = 2.6
Identities = 17/75 (22%), Positives = 32/75 (42%), Gaps = 5/75 (6%)
Query: 37 IRGLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQKYTQSNGRRPFGISAL 96
+ G ADA+ V + A + + H + +E+P V + + KY R +
Sbjct: 55 LSGSAADAQAVADMAAYQLELHGIELEEPPLVLAAANVVRNISYKY-----REDLSAHLM 109
Query: 97 IVGFDDDGISRLYQT 111
+ G+D ++Y T
Sbjct: 110 VAGWDQREGGQVYGT 124
>gi|4506205 proteasome beta 9 subunit isoform 1 proprotein [Homo
sapiens]
Length = 219
Score = 29.3 bits (64), Expect = 2.6
Identities = 17/75 (22%), Positives = 32/75 (42%), Gaps = 5/75 (6%)
Query: 37 IRGLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQKYTQSNGRRPFGISAL 96
+ G ADA+ V + A + + H + +E+P V + + KY R +
Sbjct: 65 LSGSAADAQAVADMAAYQLELHGIELEEPPLVLAAANVVRNISYKY-----REDLSAHLM 119
Query: 97 IVGFDDDGISRLYQT 111
+ G+D ++Y T
Sbjct: 120 VAGWDQREGGQVYGT 134
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 29.3 bits (64), Expect = 2.6
Identities = 18/52 (34%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Query: 159 LLEVVQSGGKNIELAIIRRNQPLKMFSAKEVELYVTEIEKEKEEAEKKKSKK 210
+L S +++ + I+RN PL+M KE E E + KEEAE+ + +K
Sbjct: 504 MLMTPTSAPRSVMKSFIKRNTPLRM-DPKEKERQRLENLRRKEEAEQLRRQK 554
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 28.9 bits (63), Expect = 3.4
Identities = 20/63 (31%), Positives = 33/63 (52%), Gaps = 11/63 (17%)
Query: 156 IKALLEVVQSGGKNIELAIIR---------RNQPLKMFSAKEVELYVTEIEKEKEEAEKK 206
+K LLE + + EL +++ +N PL S KE+E + +EKE +E E+K
Sbjct: 909 LKPLLEQKELRDRRAELILLKDSLAKSPSVKNDPLS--SVKELEEKIENLEKECKEKEEK 966
Query: 207 KSK 209
+K
Sbjct: 967 INK 969
>gi|71773415 annexin VI isoform 2 [Homo sapiens]
Length = 667
Score = 28.9 bits (63), Expect = 3.4
Identities = 28/138 (20%), Positives = 57/138 (41%), Gaps = 12/138 (8%)
Query: 22 EYAQEAVKKGSTAVGIRGLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQK 81
EY E + K +G R T R++++R+ ++ L + + +Y + +K
Sbjct: 254 EYFAERLFKAMKGLGTRDNTL-IRIMVSRSELDM----LDIREIFRTKYEKSLYSMIKND 308
Query: 82 YTQSNGRRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYT 141
+ + +S G DDD + + Y W+ +A+ R ++
Sbjct: 309 TSGEYKKTLLKLS----GGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVRPANDFN 364
Query: 142 EDAIASDSEAIKLAIKAL 159
DA D++A++ A+K L
Sbjct: 365 PDA---DAKALRKAMKGL 379
>gi|71773329 annexin VI isoform 1 [Homo sapiens]
Length = 673
Score = 28.9 bits (63), Expect = 3.4
Identities = 28/138 (20%), Positives = 57/138 (41%), Gaps = 12/138 (8%)
Query: 22 EYAQEAVKKGSTAVGIRGLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQK 81
EY E + K +G R T R++++R+ ++ L + + +Y + +K
Sbjct: 254 EYFAERLFKAMKGLGTRDNTL-IRIMVSRSELDM----LDIREIFRTKYEKSLYSMIKND 308
Query: 82 YTQSNGRRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYT 141
+ + +S G DDD + + Y W+ +A+ R ++
Sbjct: 309 TSGEYKKTLLKLS----GGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVRPANDFN 364
Query: 142 EDAIASDSEAIKLAIKAL 159
DA D++A++ A+K L
Sbjct: 365 PDA---DAKALRKAMKGL 379
>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
Length = 2479
Score = 28.5 bits (62), Expect = 4.4
Identities = 19/59 (32%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
Query: 147 SDSEAIKLAIKALLEVVQSGGKNIELAIIRRNQPLKMFSAKEVELYVTEIEKEKEEAEK 205
+D+ I L+ + E+ +N+ + + R Q L A+EVEL + E+EK EE K
Sbjct: 25 ADNLLISLSKVEVNELKSEKQENV-IHLFRITQSLMKMKAQEVELALEEVEKAGEEQAK 82
>gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]
Length = 587
Score = 28.5 bits (62), Expect = 4.4
Identities = 35/134 (26%), Positives = 59/134 (44%), Gaps = 14/134 (10%)
Query: 73 RFIATLKQKYTQSNGRRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTV 132
R I TL++ + NG GI+AL F + + R+ + T+ A A+ + KT+
Sbjct: 205 RVIGTLEEVHMPQNGINHPGITALAQAFAVNPLLRVINLN-DNTFTEKGAVAMAETLKTL 263
Query: 133 REFLEKNYTEDAIAS-DSEAIKLAIKALLEVVQSGGKNIELAIIRRNQPLKMFSAKEVEL 191
R+ N+ + + S + AI AI+ L ++ N+ I+R + L
Sbjct: 264 RQVEVINFGDCLVRSKGAVAIADAIRGGLPKLKE--LNLSFCEIKR----------DAAL 311
Query: 192 YVTEIEKEKEEAEK 205
V E +K E EK
Sbjct: 312 AVAEAMADKAELEK 325
>gi|95089461 discs large homolog 5 [Homo sapiens]
Length = 1919
Score = 28.1 bits (61), Expect = 5.7
Identities = 15/48 (31%), Positives = 27/48 (56%)
Query: 27 AVKKGSTAVGIRGLTADARVVINRARVECQSHKLTVEDPVTVEYITRF 74
A K+GS AVG R + + + N++ EC+S + +D +T+ + F
Sbjct: 749 AAKEGSLAVGDRIVAINGIALDNKSLNECESLLRSCQDSLTLSLLKVF 796
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.130 0.353
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,723,505
Number of Sequences: 37866
Number of extensions: 255488
Number of successful extensions: 1458
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 1386
Number of HSP's gapped (non-prelim): 78
length of query: 212
length of database: 18,247,518
effective HSP length: 98
effective length of query: 114
effective length of database: 14,536,650
effective search space: 1657178100
effective search space used: 1657178100
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.